Podcasts about Howard Hughes Medical Institute

Episode 130 In part 23 of our Sinai and Synapses interview series, we are talking with Dr Fred Ledley. He is a professor of natural & applied science and management at Bentley University in Waltham, MA and director of the center for integration of science and industry. A physician and pediatrician by training, he has performed research in genomics on the faculties of the Baylor College of Medicine, Texas Children's Hospital, and Howard Hughes Medical Institute and founded several biotechnology companies focused on gene therapy or personalized medicine. A widely published researcher, his current work focuses on advancing the translation of scientific discoveries for public value by developing synergies between science, medicine, business, and public policy. He has previously participated in the national, NIH-funded program in “Genetics, Religion and Ethics”, part of the ELSI program of the Human Genome project, and a Templeton-funded program “New Visions in Science, Nature and Religion” at US Santa Barbara. He has written a novel, Sputnik's Child, which explores how science and technology became a faith for members of the baby boom generation and the limits of this faith. He plays clarinet in Shpilkes Klezmer Band and has served on the board of the Boston Jewish Music Festival, Jewish Arts Collaborative, and Celebrity Series of Boston. He joined in a Bnai Mitzvah with his wife, Tamara, at age 31, occasionally reads Torah and serves as darshan as a member of Temple Aliyah in Needham MA, and considers music, hiking the forest, and observing solar eclipses to be spiritual experiences. Check out his book, "Sputnik's Child" here - https://amzn.to/4dgiZAD   Sinai and Synapses - https://sinaiandsynapses.org/   Support this podcast on Patreon at https://www.patreon.com/DowntheWormholepodcast   More information at https://www.downthewormhole.com/   produced by Zack Jackson music by Zack Jackson and Barton Willis 

Eccentric billionaire Howard Hughes founded his eponymous Medical Institute over 70 years ago devoted to “unlocking the fundamentals of biology and building an open, inclusive future for science.”Some say Howard Hughes Medical Institute is bringing its founder's vision into the future with its one-of-a-kind Janelia Research Campus in Ashburn, Virginia. On this 281-acre parcel of land, integrated teams of lab scientists and tool-builders pursue a small number of scientific questions with potential for transformative impact. To drive science forward, they share their methods, results, and tools with the scientific community.Nelson Spruston, Ph.D., the executive director at HHMI's Janelia research campus, also tells hosts Mark Masselli and Margaret Flinter about AI@HHMI, its new $500 million initiative to embed AI systems throughout every stage of the scientific process.Spruston says, “Our approach is to identify people who have a very strong track record of making important discoveries in biomedical research and letting them pursue their best ideas without asking for our permission. What we're trying to do at HHMI is to use the deep bench of talent … to come up with ideas for problems [and address] long-standing open questions in the biological sciences.” Learn more about your ad choices. Visit podcastchoices.com/adchoicesSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Originally broadcast April 10, 2025 Eccentric billionaire Howard Hughes founded his eponymous Medical Institute over 70 years ago devoted to “unlocking the fundamentals of biology and building an open, inclusive future for science.” Some say Howard Hughes Medical Institute is bringing its founder's vision into the future with its one-of-a-kind Janelia Research Campus in Ashburn, Virginia. On this 281-acre parcel of land, integrated teams of lab scientists and tool-builders pursue a small number of scientific questions with potential for transformative... Read More Read More The post Mystery No More: Howard Hughes' Legacy Advances Science appeared first on Healthy Communities Online.

Dr. Joseph S. Takahashi is Professor and Chair of Neuroscience and the Loyd B. Sands Distinguished Chair in Neuroscience at the University of Texas Southwestern Medical Center. He is also an Investigator in the Howard Hughes Medical Institute. Joe and his lab members are trying to better understand the biological clocks in our bodies that control our 24-hour schedules. Within each of us are internal clocks that are genetically controlled. A special set of genes within nearly all of our cells turns on and off each day to regulate a wide variety of biological functions, and Joe is studying these genes and how they contribute to our biological rhythms. Functions influenced by our biological clocks include our sleep schedules, blood sugar, body temperature, liver metabolism, and many other aspects of our physiology. When Joe isn't at work, he enjoys playing tennis, skiing, hiking, eating delicious food, and drinking great wine. Joe received his B.A. in biology from Swarthmore College and he was awarded his Ph.D. in neuroscience from the University of Oregon in Eugene. Afterwards, he conducted postdoctoral research as a pharmacology research associate at the National Institute of Mental Health. Before moving to UT Southwestern, Joe served on the faculty of Northwestern University for 26 years. Over the course of his career, Joe has received numerous awards and honors including the Honma Prize in Biological Rhythms Research, the NSF Presidential Young Investigator Award, the Searle Scholars Award, the Bristol-Myers Squibb Unrestricted Grant in Neuroscience, the C. U. Ariens Kappers Medal, the Outstanding Scientific Achievement Award from the Sleep Research Society, the W. Alden Spencer Award in Neuroscience from Columbia University, and the Peter C. Farrell Prize in Sleep Medicine from the Harvard Medical School Division of Sleep Medicine. He has also been elected as a Fellow of the American Academy of Arts and Sciences, a Fellow of the American Association for the Advancement of Science, a Member of the National Academy of Sciences, a Member of the National Academy of Medicine, and an Honorary Member of The Japanese Biochemical Society. In our interview, Joe shared his experiences in life and science.

After television, a big part of the ad budget for fast-food restaurants' is spent on outdoor advertising like billboards. This episode begins with the impact of that advertising and some insight into how fast-food restaurants get you to eat their food. https://www.apa.org/topics/obesity/food-advertising-children You have undoubtedly had people in your life who inspired you. What was it that made them so inspiring? What are the necessary traits of an inspiring person? How can you be more inspiring to others? That is what Adam Galinsky is here to discuss, and it is something he knows a lot about. Adam is social psychologist and Professor of Leadership and Ethics at Columbia Business School as well as the author of the book Inspire: The Universal Path for Leading Yourself and Others (https://amzn.to/3EeUYN6). Nature has a lot of rules and regulations. And those rules are what allow all the creatures and plants on earth to co-exist. We humans rely on other plants and species to do what they do to help create an environment that allows us to survive and thrive. Many of these other species we never interact with or even know about – but we are all following the rules. Here to explains these rules of how life works is Sean B. Carroll, an award-winning scientist who is vice president for science education at the Howard Hughes Medical Institute and professor of molecular biology and genetics at the University of Wisconsin–Madison. He is author of the book The Serengeti Rules: The Quest to Discover How Life Works and Why It Matters (https://amzn.to/3E69uq8). What makes a relationship work? Listen to discover what 700 married couples said was most important for a long and happy relationship – and they are things that are so simple. Source: Dr. Karl Pillemer, author of 30 Lessons For Loving (https://amzn.to/3EcsovL). Learn more about your ad choices. Visit megaphone.fm/adchoices

In the fifth Season of the National Institute of Neurological Disorders and Stroke's Building Up the Nerve podcast, we help you strengthen your science communication skills with tools and advice to use throughout your career. We know that navigating your career can be daunting, but we're here to help—it's our job!In the eighth episode of the season, we talk about Establishing Your Professional Identity, focusing on tips for defining who you are in your career, and developing skills and strategies to create and communicate who you are, or what your “brand” is, in your field and in the public.Featuring Thiago Arzua, PhD, Postdoctoral Fellow at Columbia University's Zuckerman Institute; Carmen Maldonado-Vlaar, PhD, Professor at University of Puerto Rico-Río Piedras Campus; and Erich Jarvis, PhD, Professor at Rockefeller University and Investigator at Howard Hughes Medical Institute.ResourcesPicture a Scientist: https://www.pictureascientist.com/ Black in Neuro: https://blackinneuro.com/ Ciencia Puerto Rico: https://www.cienciapr.org/ NIH Blueprint and BRAIN Initiative® ENDURE R25 Program: https://neuroscienceblueprint.nih.gov/training/endure-undergraduate-education NEURO-ID Program: https://neuroid.uprrp.edu/NeuroBoricuas at UPR Cayey: https://neuroboricuasuprcayey.wordpress.com/ Transcript available at http://ninds.buzzsprout.com/.

In this episode of the Dakota Fundraising News Podcast, Pat and Konch highlight recent job changes, including Michael Ardill joining Hymans Robertson, Bethan Brown joining Howard Hughes Medical Institute, and Michael Brand being appointed Co-head of Real Assets at Aksia. In RIA/FA M&A updates, LPL Financial recruits a $540M team from US Bank in San Diego, UBS hires Ryan Lurie to lead its Arizona wealth management team, and Wedbush expands its Philadelphia office with the McCall Connelly Group. Institutional coverage includes updates on the Davie Police Pension Plan hiring Loomis Sayles as its core fixed income manager, upcoming manager searches for the Teachers Retirement System of Louisiana, and significant commitments from plans like Maine Public Employees' Retirement System and Border to Coast. Fundraising highlights feature Pearlmark's second close on its $300M+ Mezzanine VI fund, CION and GCM Grosvenor's launch of a $300M infrastructure fund, and Prospect Capital's partnership with iCapital to boost access to its closed-end funds and BDCs. Tune in for these updates and more from the world of institutional and wealth management. 

The fifth Season of the National Institute of Neurological Disorders and Stroke's Building Up the Nerve podcast, where we help you strengthen your science communication skills with tools and advice to use throughout your career. We know that navigating your career can be daunting, but we're here to help—it's our job!In the fourth episode of the season, we talk about Crafting Effective Presentations, focusing on how presentations are used in traditional science communication and how to effectively present in different forms and venues, with accessibility built in by design.Featuring Alfredo Quiñones-Hinojosa, MD, Professor, Endowed Chair, and Dean of Research at Mayo Clinic Florida; Alicia Wooten, PhD, Co-Founder of Atomic Hands, and Associate Professor at Gallaudet University; Huda Zoghbi, MD, Professor at Baylor College of Medicine, Investigator at Howard Hughes Medical Institute, and Director at Texas Children's Hospital.Please note that Dr. Alicia Wooten conducts the interview via ASL with a voice interpreter. To watch this podcast episode with ASL interpretation, please visit: https://www.youtube.com/watch?v=6gNut7ou55g. ResourcesAtomic Hands: https://atomichands.com/Transcript available at http://ninds.buzzsprout.com/.

Michele Pagano, Chairman of the Department of Biochemistry and Molecular Pharmacology at NYU School of Medicine, takes us through his groundbreaking research on the Ubiquitin-Proteasome System and Cullin-RING Ligases. As a leading Investigator at the Howard Hughes Medical Institute, Professor Pagano shares insights into targeted protein degradation and its potential for treating “undruggable” cancer proteins. Reflecting on the evolving dynamics within academia, he discusses the challenges and intricacies of managing a research lab and offers his perspectives on the current publishing and peer review systems in scientific journals. Don't miss this engaging conversation on the challenges and opportunities shaping the future of biomedical science. Link to the paper mentioned in the show: https://breast-cancer-research.biomedcentral.com/articles/10.1186/bcr2742

All organisms from fruit flies to humans share the same mechanism for controlling the day and night rhythms also called the circadian rhythms. This mechanism is considered fundamental to all advanced life forms, and it has a surprising feature. It binds us genetically to live on earth. Michael Rosbash received the Nobel Prize in Medicine in 2017 for the discovery of the circadian rhythms together with Jeffrey Hall and Michael Young. He is a professor and Howard Hughes Medical Institute investigator at Brandeis University. In 2019 he was invited by The Royal Danish Academy of Sciences and Letters to give the nineteenth Royal Academy Nobel Laureate Lecture in Copenhagen and was interviewed by science journalist Jens Degett. Photo credit: Chris Heller for Science Stories.

The fifth Season of the National Institute of Neurological Disorders and Stroke's Building Up the Nerve podcast, where we help you strengthen your science communication skills with tools and advice to use throughout your career. We know that navigating your career can be daunting, but we're here to help—it's our job!In the first episode of the season, we talk about Composing Scientific Narratives which focused on how to compose scientific narratives to communicate our findings and how to tell a scientific story in a way that is compelling, but also transparent and objective.Featuring Sean Carroll, PhD, Balo-Simon Endowed Chair of Biology, University of Maryland; Investigator, Howard Hughes Medical Institute; Mónica Feliú Mójer, PhD, Director, Public Engagement with Science, Ciencia Puerto Rico; Director, Inclusive Science Communication & Engagement | Science Communication Lab; and Gina Poe, PhD, Director, UCLA Brain Research Institute; Lorre Scholars Faculty Chair; Professor, University of California, Los Angeles.ResourcesScience Communication Lab: https://sciencecommunicationlab.org/ Dr. Mónica Feliú Mójer's documentary: https://www.youtube.com/watch?v=WNdX_C2jaac Transcript available at http://ninds.buzzsprout.com/.

In this episode of the Award-winning PRS Journal Club Podcast, 2024 Resident Ambassadors to the PRS Editorial Board – Rami Kantar, Yoshi Toyoda, and Amanda Sergesketter- and special guest Valeriy Shubinets, MD, discuss the following articles from the September 2024 issue: “Radial and Ulnar Forearm Free Flaps: A Critical Comparison of Donor-Site Morbidity and Its Impact on Quality of Life” Al-Aroomi, Duan, Al-Worafi, et al. Read the article for FREE: https://bit.ly/RadialUlnarFF Special guest, Dr. Valeriy Shubinets, is a faculty member at The Curtis National Hand Center and MedStar Health. Originally from Ukraine, he obtained his medical degree from Harvard Medical School. He was awarded the Howard Hughes Medical Institute fellowship for a research year before he completed his plastic surgery residency at the University of Pennsylvania, followed by an orthopedic hand fellowship at The Curtis National Hand Center and Union Memorial Hospital. Dr. Shubinets has a diverse clinical practice in hand surgery with a focus on reconstruction and microsurgery including very complex replantations, and he also conducts research to better understand vascular anatomy.  READ the articles discussed in this podcast as well as free related content: https://bit.ly/JCSept24Collection

“Wisdom is not just about knowledge. Wisdom adds to knowledge with discernment, with understanding, with a moral sense of what's right and wrong.” We live in a time of overflowing and interweaving crises. A global pandemic exacerbates a mental health crisis caused social media technology. The upheaval of American electoral politics caused by an erosion (or breakdown?) of social and relational trust. The rise of nationalism, the proliferation of war, and longing for justice in the realms of gender and race. Underneath it all appears to be a crisis of knowledge and its convergence around skepticism of science, a culture of suspicion, and confusion about basic factual information, let alone right and wrong. We need wisdom. Badly. But in times of crisis and chaos, where are we to turn for wisdom? In this episode Mark Labberton is joined by longtime friend Francis Collins, physician, researcher, and former director of the National Institutes of Health (NIH). Known for his leadership in mapping the human genome, his public service at the NIH spanned three presidencies and culminated with overseeing the national response to Covid-19 pandemic. The author of many books, including his bestselling The Language of God, Collins's new book is *The Road to Wisdom: On Truth, Science, Faith, and Trust,* a reflection on the crisis of truth, science, faith, and trust, and how the exhausted middle might chart a path toward a better future. About Francis Collins Francis S. Collins, MD, PhD, is the former director of the National Institutes of Health (NIH). As the longest serving director of NIH—spanning twelve years and three presidencies—he oversaw the work of the largest supporter of biomedical research in the world, from basic to clinical research. Collins is a physician-geneticist noted for his landmark discoveries of disease genes and his leadership of the international Human Genome Project, which culminated in April 2003 with the completion of a finished sequence of the human DNA instruction book. He served as director of the National Human Genome Research Institute at the NIH from 1993 to 2008. Collins's research laboratory has discovered a number of important genes, including those responsible for cystic fibrosis, neurofibromatosis, Huntington's disease, a familial endocrine cancer syndrome, and most recently, genes for type 2 diabetes, and the gene that causes Hutchinson-Gilford progeria syndrome, a rare condition that causes premature aging. Collins received a BS in chemistry from the University of Virginia, a PhD in physical chemistry from Yale University, and an MD with honours from the University of North Carolina at Chapel Hill. Prior to coming to the NIH in 1993, he spent nine years on the faculty of the University of Michigan, where he was a Howard Hughes Medical Institute investigator. He is an elected member of the Institute of Medicine and the National Academy of Sciences. Collins was awarded the Presidential Medal of Freedom in November 2007 and the National Medal of Science in 2009. Show Notes Get your copy of The Road to Wisdom: On Truth, Science, Faith, and Trust “The crisis behind the crisis. It's the crisis of culture. It's the crisis of mind and heart. It's the crisis of society. It's the crisis of faith.” Collins occupying various roles through this book: professor, advocate, mentor, philosopher, coach, scientist, pathologist, and perhaps most saliently, cultural diagnostician. Being on the road to wisdom Helping those in the exhausted middle, to offer ways to do something to address cultural crises Collins summarizes the arc of the book TRUTH: “There is such a thing as objective truth. But it is not necessarily very popular in many circumstances.” “Facts—*established facts—*are now sometimes called into question because somebody doesn't like the fact.” Jonathan Rauch on the “Constitution of Knowledge” “You will know the truth and the truth will set you free. He doesn't say the counter that lies will imprison you, but you might have to think about that.” Science as a pathway to the truth Anecdotes vs. empirical science “We have to bring faith into this conversation if we're trying to shape a future that it gives you a chance to tap into all the wisdom that's there.” TRUST: “I found in my own experience, some of the information that turned out to be most life-changing came from a source that I never would have considered as part of my reliable circle of buddies, but I needed to hear it.” “Wisdom is not just about knowledge. Wisdom adds to knowledge with discernment, with understanding, with a moral sense of what's right and wrong.” “Our society is in trouble.” Where will the solution come from? No politicians, not media, but only us. Empowering people to be part of the solution “Love is your calling. Anger and fear are not your calling.” “Listen to understand.” Don't distribute information unless you're sure it's true. Build bridges with neighbours and within communities. Braver Angels Website “If you put information in front of people that's well established, they'll make rational decisions. And I assume that's what science is all about.” Collins's experience leading the charge to develop Covid-19 vaccines, and then managing the resistance to vaccines “People of faith in many instances were the most likely to fall into the category of not trusting what science had to say.” The cultural crisis beneath the medical crisis of Covid vaccine skepticism Collins reflects on public health responses to Covid-19 (school closures, mask mandates, etc.) Systemic breakdown caused by fear, anxiety, distrust, and suspicion Collins comments on Anthony Fauci's public service throughout Covid-19 Discrediting and redefining science, subverting faith Postmodernism and the erasure of objectivity and reason in science “Nothing is true except our perspective.” Francis Collins's perspectives on the Christian church Christians' ungrounded fear that this is a war Tim Alberta's book The Kingdom, the Power, and the Glory “Seeing through a glass darkly.” (1 Cor 13) A book of hope and whole human experience “There are profound reasons for each of us to engage. This is an argument about not standing aside. It's crucial to see that what we are fighting for is great and glorious, and worth every bit of the effort from each of us. Truth, science, faith, and trust are not just sources of relief from a painful period in our country's life. They represent the grandest achievements and insights of human civilization. They literally hold down the promise of a better life for every person on this planet in material terms, in spiritual terms, and in social and cultural terms. To take up this challenge is therefore not an act one of exhaustion or desperation. But one arising from the hopeful pursuit of the promise of greater flourishing of our entire humandom.” Production Credits Conversing is produced and distributed in partnership with Comment magazine and Fuller Seminary.

In this episode of the Award-winning PRS Journal Club Podcast, 2024 Resident Ambassadors to the PRS Editorial Board – Rami Kantar, Yoshi Toyoda, and Amanda Sergesketter- and special guest Valeriy Shubinets, MD, discuss the following articles from the September 2024 issue: “Wrist-Level Tendon Repairs Utilizing a Novel Tendon Stapler Device: An Efficiency and Biomechanical Study” by Reed, Hendrycks, Graham, et al. Read the article for FREE: https://bit.ly/StaplerDevice Special guest, Dr. Valeriy Shubinets, is a faculty member at The Curtis National Hand Center and MedStar Health. Originally from Ukraine, he obtained his medical degree from Harvard Medical School. He was awarded the Howard Hughes Medical Institute fellowship for a research year before he completed his plastic surgery residency at the University of Pennsylvania, followed by an orthopedic hand fellowship at The Curtis National Hand Center and Union Memorial Hospital. Dr. Shubinets has a diverse clinical practice in hand surgery with a focus on reconstruction and microsurgery including very complex replantations, and he also conducts research to better understand vascular anatomy.  READ the articles discussed in this podcast as well as free related content: https://bit.ly/JCSept24Collection

In this episode of the Award-winning PRS Journal Club Podcast, 2024 Resident Ambassadors to the PRS Editorial Board – Rami Kantar, Yoshi Toyoda, and Amanda Sergesketter- and special guest Valeriy Shubinets, MD, discuss the following articles from the September 2024 issue:  “Predicting Persistent Opioid Use after Hand Surgery: A Machine Learning Approach” by Baxter, Ho, Byrd, et al. Read the article for FREE: https://bit.ly/PredictingOpioidUse Special guest, Dr. Valeriy Shubinets, is a faculty member at The Curtis National Hand Center and MedStar Health. Originally from Ukraine, he obtained his medical degree from Harvard Medical School. He was awarded the Howard Hughes Medical Institute fellowship for a research year before he completed his plastic surgery residency at the University of Pennsylvania, followed by an orthopedic hand fellowship at The Curtis National Hand Center and Union Memorial Hospital. Dr. Shubinets has a diverse clinical practice in hand surgery with a focus on reconstruction and microsurgery including very complex replantations, and he also conducts research to better understand vascular anatomy.  READ the articles discussed in this podcast as well as free related content: https://bit.ly/JCSept24Collection

About the sponsor: Empower yourself with access to diverse perspectives and improve your media consumption habits by subscribing through this link: https://ground.news/bigthink for 40% off unlimited access this month with the Vantage Subscription and be the change you want to see. About the video: Biological evolution in humans has slowed. Can AI, culture wars, and modern tech explain why? Up next, What are the chances of YOU existing? A biologist explains ►   • What are the chances of YOU existing?...   In modern times, our lives have changed tremendously by gaining control over nature. The advent of vaccines, antibiotics, antivirals, and better sanitation has dramatically reduced our physiological challenges. In the present day, we enjoy a much more secure food supply than we did a hundred years ago. We live at a time where cultural evolution can be very, very, very rapid, but our biological evolution seems relatively stunted. Why is this? Why is everything about our civilization changing constantly, except our bodies? Biologist and author Sean B. Carroll unveils why biology isn't evolving as rapidly as culture. -------------------------------------------------------------- About Sean B. Carroll: Sean B. Carroll is an award-winning scientist, author, educator, and film producer. He is Distinguished University Professor and the Andrew and Mary Balo and NIcholas and Susan Simon Chair of Biology at the University of Maryland, and an Investigator of the Howard Hughes Medical Institute. He was formerly Head of HHMI Tangled Bank Studios, and led the Department of Science Education from 2010-2023. He is also Professor Emeritus of Genetics and Molecular Biology at the University of Wisconsin Learn more about your ad choices. Visit megaphone.fm/adchoices

- Ph.D. degree in Biochemistry and Molecular Biology. School of Medicine. Universidad Autónoma de Madrid (Spain) - Postdoctoral researcher at the Howard Hughes Medical Institute and Department of Biology, University of California, San Diego (USA) - Associate Researcher at the Medical Research Center, Laboratory of Molecular Biology, Cambridge (UK) - Staff Researcher at the Spanish Council for Scientific Research - Topics of research: molecular genetics, neurobiology, and cancer - Over 1200 scientific citations - Currently unaffiliated with academic institutions The main points from the presentation are: 1. Any annual deviation from the long-term warming trend is due to natural variability. It cannot be due to human causes. 2. Years that are warmer than the long-term trend are eventually compensated by cooler years, so the long-term trend remains, but only the warmer years become newsworthy. 3. The 2023-2024 climate event cannot be reproduced by models because they are notoriously bad at reproducing natural variability, and the Hunga Tonga eruption is unprecedented, so its full effects are unknown. The effect of the eruption is uncharted territory, not the current climate situation. 4. Although 2023 and 2024 are natural deviations from the long-term trend, there is a concerted effort by the UN and some scientists to blame them on human emissions in order to advance the energy transition agenda. 5. After a series of years that are warmer than the long-term trend, we should have a series of years that are cooler than the long-term trend because the cause of global warming responsible for the trend has not been affected. So just waiting will fix the volcanic anomaly. 00:00 Introduction and Importance of Climate Events 00:47 Analyzing the 2023 Climate Event 01:37 Temperature Records and Trends 03:24 Ocean Temperature Anomalies 05:28 Unprecedented Warming and Scientific Puzzles 06:22 Potential Causes of Abrupt Warming 12:27 Volcanic Eruptions and Climate Impact 19:46 Natural Variability vs. Human Impact 25:20 Future Climate Predictions and Adaptation 35:42 Conclusion and Final Thoughts Vinos' “Science and Climate” YouTube channel: https://www.youtube.com/@ScienceClimate-uf4xm More of Javier's work on Andy May's site: https://andymaypetrophysicist.com/ ========= AI summaries of all of my podcasts: https://tomn.substack.com/p/podcast-summaries My Linktree: https://linktr.ee/tomanelson1 YouTube: https://www.youtube.com/playlist?list=PL89cj_OtPeenLkWMmdwcT8Dt0DGMb8RGR X: https://twitter.com/TomANelson Substack: https://tomn.substack.com/ About Tom: https://tomn.substack.com/about

Aging may be on your mind this week. And it's an often overlooked aspect of planning for retirement. Coleen T. Murphy, a leading scholar of aging, and the author of How We Age: The Science of Longevity, details how recent research on model systems, combined with breakthroughs in genomic methods, have allowed scientists to probe the molecular mechanisms of longevity and aging, This research is helping us understand the fundamental biological rules that govern aging - and it may be bringing us closer to extending healthspans and slowing the effects of aging. She joins us here in Princeton, New Jersey. __________________________ Bio Coleen T. Murphy is professor of genomics and molecular biology at Princeton University. She is director of Princeton's Glenn Foundation for Research on Aging and director of the Simons Collaboration on Plasticity in the Aging Brain. She is director of the Paul F. Glenn Laboratories For Aging Research at Princeton. Murphy completed a B.S. with honors in biochemical and biophysical sciences at the University of Houston and earned a Ph.D. at Stanford University. She was awarded a graduate fellowship at Howard Hughes Medical Institute and completed her postdoctoral work at the University of California, San Francisco. ___________________________ For More on Coleen T. Murphy How We Age: The Science of Longevity ___________________________ Podcast Episodes You May Like Why We Remember – Charan Ranganath How Not to Age – Dr. Michael Greger The Mindful Body – Ellen Langer ___________________________ Wise Quotes On Why We Age "I think if the better question is why wouldn't we age? Like in the entire universe, entropy is at work. So things fall apart and unless you put in energy to repair them, those things will fall apart. So we're no different, but just we're better at repairing all of our cells and tissues and everything else when we're young, right? My kids, if they get a cut, it heals up in like two days. And if I do, it doesn't. So we see those repair processes decline with age. And so that's really why we age because the amount that our body's put into repair actually gets overwhelmed at some point." On Cognitive Aging "So, by studying processes that change with age, my lab is extremely interested in cognitive aging. So we want to make that extend as long as possible. Even if it didn't extend lifespan, if we found a mechanism to maintain your cognitive function as long as possible, that would be super valuable for all of us. And so, that's what we're talking about when we're talking about healthspan. A lot of these age -related diseases that we care about in humans and then we understand the molecular mechanisms so that we can find ways to extend that in humans as well...Can we actually extend the you know the time of normal cognitive function? And it turns out we've been able to uncover pathways that do control that. So I'm really excited about some work that we did where we you know we found some we found a genetic pathway where if we flipped on just one protein made it more active in one neuron of the cell. Admittedly they have hardly any neurons - they have only 302. But this particular neuron is one that's really important for regulating their memory and we turn that on a super old worm and it rescued their memory. Nobody really cares until you show it in a mouse. And so we collaborated with friends of ours at UCSF and they put in into the hippocampus so the brain of the two -year -old mice. So that's like a 75 to 80 year old person. They put in the same activated protein in these it. rescue their memory. So that shows that we can use these pathways to find something in worms and apply it to mammals. And by the way, that protein is exactly the same in mice and humans. So that gives us sort of a way into this problem where we could start to address it pharmaceutically. So that's an example. I don't think it's the only way.

- Ph.D. degree in Biochemistry and Molecular Biology. School of Medicine. Universidad Autónoma de Madrid (Spain) - Postdoctoral researcher at the Howard Hughes Medical Institute and Department of Biology, University of California, San Diego (USA) - Associate Researcher at the Medical Research Center, Laboratory of Molecular Biology, Cambridge (UK) - Staff Researcher at the Spanish Council for Scientific Research - Topics of research: molecular genetics, neurobiology, and cancer - Over 1200 scientific citations - Currently unaffiliated with academic institutions "The Winter Gatekeeper is a thermodynamic theory of climate change. Changes in winter heat transport to the Arctic alter the infrared emissions of the planet because the greenhouse effect is much weaker there. The Sun changes the climate through this mechanism." 00:00 Introduction to Javier Vinos and His Work 00:46 The Sun's Influence on Climate 03:09 Evidence from the Holocene Period 07:58 Grand Solar Minima and Climate Impact 09:31 Human Population and Climate Correlation 10:46 Challenges to IPCC and NASA's Views 11:27 Solar Activity and Modern Climate 20:33 Solar Influence on Atmospheric Circulation 23:51 The Earth's Rotation and Solar Activity 29:00 Alternative Theories and IPCC Critique 30:57 Cosmic Rays and Climate Change 31:21 The Svensmark Theory 31:47 Introducing the Third Theory 32:28 Heat Transport and Climate 33:19 Challenges in Measuring Heat Transport 34:19 Heat Transport's Role in Climate Change 37:28 The Winter Gatekeeper Theory 38:20 Solar Activity and Planetary Waves 42:41 Implications of the Winter Gatekeeper Theory 47:26 Concluding Thoughts and Future Research Author of the Nov. 2023 book: “Solving the Climate Puzzle”: https://a.co/d/fsIts54 Author of the 2022 book: “Climate of the Past, Present and Future. A scientific debate, 2nd ed.”: https://www.amazon.com/Climate-Past-Present-Future-scientific-ebook/dp/B0BCF5BLQ5/ Three-part “How we know that the sun changes the Climate” series on Judith Curry's blog: https://judithcurry.com/2024/06/11/how-we-know-the-sun-changes-the-climate-iii-theories/ Vinos' “Science and Climate” YouTube channel: https://www.youtube.com/@ScienceClimate-uf4xm More of Javier's work on Andy May's site: https://andymaypetrophysicist.com/ ========= AI summaries of all of my podcasts: https://tomn.substack.com/p/podcast-summaries My Linktree: https://linktr.ee/tomanelson1 YouTube: https://www.youtube.com/playlist?list=PL89cj_OtPeenLkWMmdwcT8Dt0DGMb8RGR X: https://twitter.com/TomANelson Substack: https://tomn.substack.com/ About Tom: https://tomn.substack.com/about

Ready to reduce your caffeine? Visit https://MUDWTR.com/bigthink and receive $20 off and free frother. “If given a chance, nature can rebound, and nature can rebound dramatically.” Biologist Sean B. Carroll discusses the resilience of nature and how humans can help it thrive. Humans litter, start wars, hunt, and poach, but history has also shown we are capable of undoing our damage. Carroll highlights Gorongosa National Park in Mozambique, where a brutal civil war decimated 98% of the large animal population. Yet, through dedicated conservation efforts, the park has seen a remarkable recovery – and this is not the only example. This video explores the power of awareness and action—no matter how small. While humans have caused significant damage to wildlife, we also possess the ability to restore and protect our planet's biodiversity. Carroll shares insights on how we can coexist with nature, ensuring a healthy and happy future for both humans and other creatures on Earth. ---------------------------------------------------------------------------------------------------------------- Go Deeper with Big Think: ►Become a Big Think Member Get exclusive access to full interviews, early access to new releases, Big Think merch and more ►Get Big Think+ for Business Guide, inspire and accelerate leaders at all levels of your company with the biggest minds in business ---------------------------------------------------------------------------------- About Sean B. Carroll: Sean B. Carroll is an award-winning scientist, author, educator, and film producer. He is Distinguished University Professor and the Andrew and Mary Balo and NIcholas and Susan Simon Chair of Biology at the University of Maryland, and an Investigator of the Howard Hughes Medical Institute. He was formerly Head of HHMI Tangled Bank Studios, and led the Department of Science Education from 2010-2023. He is also Professor Emeritus of Genetics and Molecular Biology at the University of Wisconsin. An internationally-recognized evolutionary biologist, Carroll's laboratory research has centered on the genes that control animal body patterns and play major roles in the evolution of animal diversity. In recognition of his scientific contributions, Carroll has received the Benjamin Franklin Medal in Life Sciences, been elected to the National Academy of Sciences and the American Philosophical Society, named a Fellow of the American Academy of Arts and Sciences and the American Association for the Advancement of Science, and elected an Associate Member of the European Molecular Biology Organization. His latest book is A Series of Fortunate Events ► https://press.princeton.edu/books/har... Learn more about your ad choices. Visit megaphone.fm/adchoices

Welcome to the Empowerment Hour with Host Michelle Bolden and Special Guests Phyllis Box and her son Anthony Box. Topic:  Peace of Mind:  A Mother and Son's Story Tune in to this touching episode as a mother and son share their story and journey living with mental illness. Phyllis (the mom) is the founder of "Phyl Good...About Your Health", and skilled at helping you create a healthy lifestyle. She has been working in the field of health promotion with clients in corporate settings, groups and one on one. Clients include JPMorgan Chase, USPS corporate headquarters, Exxon Mobil, Howard Hughes Medical Institute, YMCA, and a host of federal agencies. Whether in a group or an individual setting, she brings compassion, listening skills and joy for helping you reach your goals. With a BS in Business Administration from Florida A&M University and a MS in Health Promotion Management from American University, Phyllis is poised and ready with years of experience. Anthony Box Jr. ("AJ" Phyllis's son) is a 26 year old Accounting Major at Morehouse College. AJ has been diagnosed with schizophrenia for 5+ years and in is interested in sharing his experience with those who are in similar situations. We want to hear from you!  Leave us a comment and subscribe to the show at www.up2meradio.com/call-for-caring-presents-the-empowerment-hour/ Like and follow us on Facebook at Up2Me Radio and Instagram at Up2Me.radio. Thank you for tuning in!

Akiko Iwasaki, Ph.D., is a Sterling Professor of Immunobiology and Molecular, Cellular, and Developmental Biology at Yale University, and an Investigator of the Howard Hughes Medical Institute. She received her Ph.D. from the University of Toronto in Canada and her postdoctoral training from the National Institutes of Health. Her research focuses on the mechanisms of immune defense against viruses at the mucosal surfaces, and the development of mucosal vaccine strategies. She is the co-Lead Investigator of the Yale COVID-19 Recovery Study, which aims to determine the changes in the immune response of people with long COVID after vaccination. Dr. Iwasaki also leads multiple other studies to interrogate the pathobiology of long COVID, both in patients, and through developing animal models of long COVID. Dr. Iwasaki was elected to the National Academy of Sciences in 2018, to the National Academy of Medicine in 2019, to the European Molecular Biology Organization in 2021, and to the American Academy of Arts and Sciences in 2021.

*The award lecture and its accompanying slides are also available to watch here: https://youtu.be/h8-_Kyqyoq0. The ASBMB William C. Rose Award for Exemplary Contributions to Education recognizes an individual who demonstrates an exceptional contribution to the teaching of biochemistry and molecular biology. Peter J. Kennelly is a professor at the Virginia Polytechnic Institute and State University, where he also serves as interim head of the biochemistry department. Kennelly earned his Ph.D. from Purdue University in 1985 and completed postdoctoral research at the University of Washington School of Medicine with support from the Howard Hughes Medical Institute. Learn more: https://www.asbmb.org/asbmb-today/people/081623/asbmb-names-2024-award-winners.

About the guest: Andrew Dillin, PhD is Professoer of Molecular & Cell Biology at UC-Berkeley and Howard Hughes Medical Institute investigator. His lab studies mechanisms of aging, mitochondrial biology, and related subjects.Episode summary: Nick and Dr. Dillin discuss: cell biology; mitochondria & the endoplasmic reticulum; aging & autophagy; mitochondrial biology in neurons; diet, exercise, and oxygen effects on mitochondrial health; and more.*This content is never meant to serve as medical advice.Support the Show.All episodes (audio & video), show notes, transcripts, and more at the M&M Substack Try Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.Try SiPhox Health—Affordable, at-home bloodwork w/ a comprehensive set of key health marker. Use code TRIKOMES for a 10% discount.Try the Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for $50 off.Learn all the ways you can support my efforts

Compare coverage and stay informed on breaking news by subscribing through my link https://ground.news/bigthink to receive 40% off unlimited access through the Vantage subscription. Humanity has two giant collisions to thank for its existence, explains biologist Sean B. Carroll. When an asteroid landed on the Yucatan peninsula 66 million years ago, it turned our planet into a debris field of chemicals that, eventually, fostered human life. Sean B. Carroll, author and esteemed biologist, unpacks the consequences of this collision, and claims we, as a species, should feel fortunate that we're on this planet at all. This historical cosmic event, paired with the tectonic movement of Earth's plates and the initiation of the Ice Age, ultimately led to existence as we know it today. Without these random, chance environmental and biological encounters, the development of life would have been stunted, or even entirely nonexistent. Even the sequence of human conception is random and unlikely, Carroll explains, leading us to reevaluate our understanding of evolution, true survival, and the significance of each individual life. ---------------------------------------------------------------------------------- Go Deeper with Big Think: ►Become a Big Think Member Get exclusive access to full interviews, early access to new releases, Big Think merch and more ►Get Big Think+ for Business Guide, inspire and accelerate leaders at all levels of your company with the biggest minds in business ---------------------------------------------------------------------------------- About Sean B Carroll: Sean B. Carroll is an award-winning scientist, author, educator, and film producer. He is Distinguished University Professor and the Andrew and Mary Balo and NIcholas and Susan Simon Chair of Biology at the University of Maryland, and an Investigator of the Howard Hughes Medical Institute. He was formerly Head of HHMI Tangled Bank Studios, and led the Department of Science Education from 2010-2023. He is also Professor Emeritus of Genetics and Molecular Biology at the University of Wisconsin. An internationally-recognized evolutionary biologist, Carroll's laboratory research has centered on the genes that control animal body patterns and play major roles in the evolution of animal diversity. In recognition of his scientific contributions, Carroll has received the Benjamin Franklin Medal in Life Sciences, been elected to the National Academy of Sciences and the American Philosophical Society, named a Fellow of the American Academy of Arts and Sciences and the American Association for the Advancement of Science, and elected an Associate Member of the European Molecular Biology Organization. Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Bob Lefkowitz is currently the Chancellor's Distinguished Professor of Medicine and Professor of Biochemistry and Chemistry at the Duke University Medical Center. He's been an investigator of the Howard Hughes Medical Institute since 1976, and he began his research career in the late 1960s and early 1970s when there was not a clear consensus that specific receptors for drugs and hormones even existed. He's a trailblazer. He's a ground breaker. He's a Nobel Prize winner. He's an author; his memoir, A Funny Thing Happened on the Way to Stockholm, recounts his early career as a cardiologist and his transition to biochemistry. He is a researcher, he's a teacher, and he's just very very wise. And sometimes you meet knowledgeable people, smart people, who lack wisdom and emotional intelligence; that's not what you're going to find in this conversation. We talk as much about philosophy as we do about his groundbreaking research. This conversation was inspiring, it made me think, and it made me question how I think, which is the sign of a great conversation. He has won numerous awards as well; he's been acknowledged by his field in a multitude of ways and at Duke University. The work that he's done finding these receptors and working on proteins has led to a discovery that impacts 30-50% of all medications that we take. He is someone who cares deeply about making an impact and influencing our society for the better. Bob had several amazing insights during our conversation. Some of them include: “Tell me your strongest asset and it will also be your biggest deficiency” (6:30). “The most important characteristic necessary for success at anything is focus” (7:05). “A totally fulfilling life needs to be one that embraces not just whatever your passion and obsession is, but a host of other things” (7:30). “I'll continue to be a work in progress” (9:00). “I have found as I'm aging that friendships have become more and more important to me” (13:10). “Life is so filled with surprises and twists and turns” (16:20). “Nobody's smart enough to make truly amazing discoveries because they're so far outside the frame of how we currently understand things that nobody's that smart” (19:50). “What I loved the most when I was younger and was at the peak of my power was making discoveries” (25:50). “The more you know, the less able you are to make discoveries” (29:30). “Each of us has a unique personality which is shaped in varying extents by the nature and the nurture” (30:50). “Education is a double-edged sword. On one hand we need education to get certain facts and ways of thinking, but also it constrains us” (31:25). “This inherent skepticism I've always had led to burning curiosity” (34:10). “What drives me the most and gives me the most satisfaction is mentoring young people” (34:50). “It is an interesting and a life-changing experience to win the Nobel Prize” (40:55). “Winning awards was not a factor. I was just driven because I was driven [to discover]” (41:15). “The whole nature of science is that whatever it is, you have to do it first. You don't get any credit for doing something second” (46:45). “Questions are a reflection of curiosity” (56:35). “Every experiment is a question. The better framed the experiment, the more likely you are to get an informative answer” (56:45). “The best outcomes in medicine are when the patient and doctor form an alliance” (57:40). “I thought [when I was younger] the most heroic thing you could do was become a physician because you could alleviate human suffering” (1:04:40). “I'm so focused in what I'm doing or who I'm interacting with that the time just disappears” (1:16:45). Additionally, you can learn more about Bob and his work here. Thank you so much to Bob for coming on the podcast! I wrote a book called “Shift Your Mind” that was released in October of 2020, and you can order it on Amazon and Barnes and Noble. Additionally, I have launched a company called Strong Skills, and I encourage you to check out our new website https://www.strongskills.co/. If you liked this episode and/or any others, please follow me on Twitter: @brianlevenson or Instagram: @Intentional_Performers. Thanks for listening.

Dr. Lin Tian is a Scientific Director at the Max Planck Florida Institute for Neuroscience and Clinical Professor at the University of California, Davis. The main goal of Lin's lab is to develop, leverage, and also share novel optical and molecular tools that can help us to characterize neural signaling and find new treatment targets for neuropsychiatric disorders. In addition to her scientific and leadership roles, Lin is a mom, wife, and daughter. She often spends her free time with her family, driving her two sons to different activities, cheering for them at their swim meets and baseball games, and helping them with homework. Lin also enjoys walking her dog and doing things around the house. She earned her B.S. in Neuroscience from the University of Science and Technology of China and her Ph.D. in Biochemistry, Molecular, and Cellular Biology from Northwestern University. She then completed postdoctoral training at Howard Hughes Medical Institute's Janelia Research Campus. Lin remained at HHMI as a Research Specialist before joining the faculty at the University of California, Davis School of Medicine in 2012. She began her current position at Max Planck in 2023. Lin has received multiple awards and honors, including an NIH New Innovator Award, the W.M. Keck Foundation Award, the Human Frontier Science Program Young Investigator Award, and she has been named a Rita Allen Scholar and Hartwell Scholar. In our interview, she shares more about her life and science.

On April 4, 2024 we had a chance to talk to Kara Marshall about the membrane protein PIEZO2, which is responsible for sensory transduction of many of the mechanical senses, including light touch, vibration, and proprioception. We especially focused on its function in sensing internal pressure and movement, including bladder pressure and blood pressure. Guest: Kara Marshall, Assistant Professor, Department of Neuroscience and Howard Hughes Medical Institute, Baylor College of Medicine Participating: Lindsey Macpherson, Department of Neuroscience, Developmental and Regenerative Biology, UTSA Host: Charles Wilson, Department of Neuroscience, Developmental and Regenerative Biology, UTSA Thanks to Jim Tepper for original music

The Howard Hughes Medical Institute investigator discusses what drew him to study the brain and his current work at the University of California, San Francisco.

The Howard Hughes Medical Institute investigator discusses what drew him to study the brain and his current work at the University of California, San Francisco.

In this episode, we are delving into the fascinating topic of mind uploading. We suspect this idea is about to explode into public consciousness, because Nick Bostrom has a new book out shortly called “Deep Utopia”, which addresses what happens if superintelligence arrives and everything goes well. It was Bostrom's last book, “Superintelligence”, that ignited the great robot freak-out of 2015.Our guest is Dr Kenneth Hayworth, a Senior Scientist at the Howard Hughes Medical Institute's Janelia Farm Research Campus in Ashburn, Virginia. Janelia is probably America's leading research institution in the field of connectomics – the precise mapping of the neurons in the human brain.Kenneth is a co-inventor of a process for imaging neural circuits at the nanometre scale, and he has designed and built several automated machines to do it. He is currently researching ways to extend Focused Ion Beam Scanning Electron Microscopy imaging of brain tissue to encompass much larger volumes than are currently possible.Along with John Smart, Kenneth co-founded the Brain Preservation Foundation in 2010, a non-profit organization with the goal of promoting research in the field of whole brain preservation.During the conversation, Kenneth made a strong case for putting more focus on preserving human brains via a process known as aldehyde fixation, as a way of enabling people to be uploaded in due course into new bodies. He also issued a call for action by members of the global cryonics community.Selected follow-ups:Kenneth HayworthThe Brain Preservation FoundationAn essay by Kenneth Hayworth: Killed by Bad PhilosophyThe short story Psychological Counseling for First-time Teletransport Users (PDF)21st Century MedicineJanelia Research CampusMusic: Spike Protein, by Koi Discovery, available under CC0 1.0 Public Domain Declaration

We kick off this episode with a communication game, then are joined by our guest, Hazel Meda. Hazel Meda is the Internal Communications Manager at Howard Hughes Medical Institute, Inc. She shares her top guidelines to ensure your communications are strategic, effective, and efficient. Hazel's framework for communication: ASSET - audience centered, simple, short, engaging, and tidy. If you enjoy our show, share it with a friend! Share it online with your network! Follow/subscribe to make sure you never miss an episode.

Sean B. Carroll, PhD is an evolutionary developmental biologist at the University of Maryland, who recently stepped down as VP of Education at the Howard Hughes Medical Institute. He is the author of many popular science books, such as "Endless Forms Most Beautiful." They discuss: developmental biology & genetics; evolutionary biology; genetics, genome size & genetic mutation; animal diversity; snake venom; human brain evolution; and more.Support the showFind all podcast & written content at the M&M Substack:[https://mindandmatter.substack.com/?sort=top]Learn how you can further support the podcast: [https://mindandmatter.substack.com/p/how-to-support-mind-and-matter]Try Athletic Greens: Comprehensive & convenient daily nutrition product. Free 1-year supply of vitamin D with purchase.[https://drinkag1.com/partner/nutrition/ctr?utm_medium=influencer&utm_term=variable__a2139__o19&utm_content=health__a2139__o19&utm_source=podcast&utm_campaign=mindandmatter_d35ct__a2139__o19]Try SiPhox Health—Affordable, at-home bloodwork w/ a comprehensive set of key health marker. Use code TRIKOMES for a 10% discount.

I got the opportunity to talk to Dr. Robert Tjian, former President of the Howard Hughes Medical Institute, about how Amygen acquired his startup, Tularik, for more than a billion dollars, venture capitalist experience, and transcription factors.Thanks to the sponsors:Audible:Use my link for a 30-day free trial: http://audibletrial.com/diamondgoatNewsly:https://newsly.me promo code to receive a 1-month free premium subscription: EARLYMORNINGLibysnhttps://libsyn.compromo code: DGDubby Energyhttps://www.dubby.ggpromo code for 10% off: DIAMONDGOATspikeviewhttps://www.spikeview.comhttps://www.instagram.com/spikeviewSwift Gripshttps://swiftgrips.netPromo code for 10% off: Diamondgoat----------------------------------------------------------------------------------Listen on:Podcast website: https://anchor.fm/diamondgoatSpotify: https://open.spotify.com/show/0EuhA6WyuerHtVAqcFrFeOApple Podcast: https://podcasts.apple.com/us/podcast/dg-early-morning-show/id1575451533 Amazon Music: https://music.amazon.com/podcasts/f050b86c-1dad-4bc3-b12f-6aa5fa62438c Tiktok: @dgearlymorningshowPodcast YT channel clips: https://www.youtube.com/@dgearlymorningshowGoogle Podcast: https://www.google.com/podcasts?feed=aHR0cHM6Ly9hbmNob3IuZm0vcy80NzE4MzM5MC9wb2RjYXN0L3Jzcw==RadioPublic: https://radiopublic.com/dg-earlymorning-show-WoML4rBreaker: https://www.breaker.audio/dg-early-morning-show Reason: https://reason.fm/podcast/dg-earlymorning-show--------------------------------------Check out my other stuff:Instagram: @itzdiamondgoatTwitter: @lildiamondgoatMain YT channel: youtube.com/diamondgoatTiktok: @lildiamondgoatSoundcloud: @Lil DiamondgoatSpotify: @Lil DiamondgoatMerch store: https://diamondgoat.creator-spring.com

What if AI could tell us we have cancer before we show a single symptom? Steve Quake, head of science at the Chan Zuckerberg Initiative, explains how AI can revolutionize science. AI can help us understand complex systems like our cells. better. The Chan Zuckerberg Initiative is committed to building one of the world's biggest non-profit life science AI computing clusters to help build digital models of what goes wrong in cells when we get diseases like diabetes or cancer and more. We created this video in partnership with the Chan Zuckerberg Initiative. ---------------------------------------------------------------------------------- About Steve Quake: Steve Quake oversees a shared, comprehensive strategy across the CZ Science program and technology teams, the CZ Biohub Network, and the Chan Zuckerberg Institute for Advanced Biological Imaging. His research is at the nexus of biology, physics, and technology development. He has invented many measurement tools for biology, including new DNA sequencing technologies that have enabled rapid analysis of the human genome, and microfluidic automation that allows scientists to efficiently isolate cells for single-cell biology. Quake is also the Lee Otterson Professor of Bioengineering and professor of applied physics at Stanford University. He joined Stanford in 2005 to help found and lead Stanford's then-new bioengineering department as it grew to nearly two dozen faculty members. He was an Investigator at the Howard Hughes Medical Institute from 2006 to 2016. Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr Robert Joseph Lefkowitz is an American physician, biochemist and Nobel Prize winner. He is best known for his groundbreaking discoveries that reveal the inner workings of an important family G protein-coupled receptors, for which he was awarded the 2012 Nobel Prize for Chemistry with Brian Kobilka. He is currently an Investigator with the Howard Hughes Medical Institute as well as a James B. Duke Professor of Medicine and Professor of Biochemistry and Chemistry at Duke University. Connect with us: https://freedompact.co.uk/newsletter​ (Healthy, Wealthy & Wise Newsletter) https://instagram.com/freedompact​ https://tiktok.com/personaldevelopment https://twitter.com/freedompactpod freedompact@gmail.com Connect with Dr Lefkowitz: https://medicine.duke.edu/profile/robert-j-lefkowitz http://pegasusbooks.com/books/a-funny-thing-happened-on-the-way-to-stockholm-9781643136387-hardcover

Darrell Irvine obtained an Honors Bachelor's degree in engineering physics from the University of Pittsburgh. As a National Science Foundation graduate fellow, he then studied Polymer Science at MIT. Following completion of his PhD, he was a Damon Runyon-Walter Winchell postdoctoral fellow in immunology at the Beckman Center for Molecular and Genetic Medicine. He is presently a professor at the Massachusetts Institute of Technology and an investigator of the Howard Hughes Medical Institute. He is also an Associate Director for the Koch Institute and serves on the steering committee of the Ragon Institute of MGH, MIT, and Harvard. Irvine is the founder of Elicio Therapeutics, Strand Therapeutics, and Ankyra Therapeutics. He serves on the Scientific Advisory Boards of the MGH Cancer Center, the University of Toronto Medicine by Design Consortium, Venn Therapeutics, Alloy Therapeutics, Jupiter Therapeutics, Parallel Bio, Surge Therapeutics, and Gensaic Therapeutics.w/ Special Guest Host: Jacob Becraft - Co-Founder & CEO @ Strand TherapeuticsJake Becraft is a synthetic biologist and entrepreneur. He is the co-founder and CEO of Strand Therapeutics, and serves on its Board of Directors. Together with colleagues at MIT's renowned Synthetic Biology Center, he led the development of the world's first synthetic biology programming language for mRNA. Jake has been featured in Fierce Biotech, Bloomberg, the Boston Business Journal, and BioCentury, among others, for his vision and mission at Strand of applying this unique platform for real world disease applications. He has also been the recipient of prestigious national and international awards for his scientific and entrepreneurial achievements, including the Barry Goldwater Scholarship and Excellence in Education Award, the Andrew Viterbi Fellowship of MIT, Amgen Fellowship, and the Bristol-Myers Squibb 2018 Golden Ticket for recognition of Strand as an innovative startup. Beyond his work at Strand, Jake's broader interests span synthetic biology, biologically engineered organism-machine interfaces, and the intersection of tech and biotech methodologies. He is an advocate among the life science entrepreneurial ecosystem for supporting young founders in biotech entrepreneurship. Currently, he serves on the advisory board of Starlight Ventures, an early stage venture firm, and also serves on the Executive Board of Public Health United, a non-profit focused on helping scientists better communicate their research for maximum impact. Previously, he served as a Science and Technology advisor to legislators in the Massachusetts State Legislature. Jake received his Ph.D. in Biological Engineering and Synthetic Biology from MIT and his B.S. in Chemical and Biomolecular Engineering from the University of Illinois at Urbana-Champaign, graduating Magna cum Laude with distinction. He is an author or inventor on numerous high profile publications, patents and white papers, including in top tier journals such as Nature Chemical Biology and PNAS.Alix Ventures, by way of BIOS Community, is providing this content for general information purposes only. Reference to any specific product or entity does not constitute an endorsement nor recommendation by Alix Ventures, BIOS Community, or its affiliates. The views & opinions expressed by guests are their own & their appearance on the program does not imply an endorsement of them nor any entity they represent. Views & opinions expressed by Alix Ventures employees are those of the employees & do not necessarily reflect the view of Alix Ventures, BIOS Community, affiliates, nor its content sponsors.Thank you for listening!BIOS (@BIOS_Community) unites a community of Life Science innovators dedicated to driving patient impact. Alix Ventures (@AlixVentures) is a San Francisco based venture capital firm supporting early stage Life Science startups engineering biology to create radical advances in human health.Music: Danger Storm by Kevin MacLeod (link & license)

In December 2023, a Montgomery County jury heard a disability discrimination case against one of the world's largest medical science philanthropies, the Chevy Chase-based Howard Hughes Medical Institute, in a lawsuit brought by one of its former research scientists, Vivian Cheung. Sunil Dasgupta asked Cheung about the case and its implications for scientific rigor, peer review, and disability accommodation. Local news: new statewide housing legislation shapes up. Music for this episode comes from 1923; sound recordings from that year just entered the public domain. National Jukebox: https://t.ly/DDGgx.

In this episode of the podcast, host Roger Knecht engages in a dynamic conversation with Sam Mendelsohn, a CPA and Mergers and Acquisitions expert. Together, they dive deep into the world of accounting, business valuation, and the critical role accounting professionals can play in helping business owners realize their company's true potential.6   Your Host: Roger Knecht, president of Universal Accounting Center Guest Name: Sam Mendelsohn, CPA Sam Mendelsohn is the President and Chief Operating Officer at The Value Builder System™. Sam is also a former Vice President within an operating division of the Constellation Group (TSE:CSU). Sam has led marketing for over 20 different brands and is a highly-rated MacKay speaker on marketing. He has also delivered over 500 software deployments ranging from marketing systems to full Enterprise Resource Planning systems and corporate performance management systems at companies including Microsoft, Merck, Howard Hughes Medical Institute and Sun Media.   Highlights: Sam shares his journey from traditional accounting to specializing in mergers and acquisitions, emphasizing the importance of business valuation. They discuss how understanding a business's true value can make a significant difference in decision making, especially during a potential sale. Sam reveals how crucial it is for business owners to continuously monitor and improve eight key drivers of business value. Roger and Sam explore real-life scenarios where two seemingly identical businesses can have vastly different valuations. They emphasize the shift accountants can make into the CFO and advisory services space, helping business owners maximize profitability, navigate operational challenges, and achieve long-term growth. Sam introduces the concept of a "showroom-ready" business and discusses the pivotal role accountants can play in preparing businesses for potential sales. They share insights on how aspiring entrepreneurs can start an accounting business, a bookkeeping business, or a tax business, and highlight the importance of learning bookkeeping online and taking online tax courses. Discover how understanding business valuation and the eight key drivers can be the catalyst for both accountants and their clients to achieve extraordinary success in the world of CFO and advisory services. Notable Quotes from this episode: "Those eight drivers are similar to going and buying a home... You're going down this checklist of what that house is going to consist of. Well, it's the same thing with the business." "Your business should always be showroom ready." "Find a good framework that you're comfortable leveraging... show up and have that conversation with the client rather than being scared about what to talk about." "Accountants have such an opportunity to look beyond the income statement, balance sheet, and cash flow statement and really do a lot of good for business owners on the operational side." Join Roger and Sam in this thought-provoking discussion as they highlight the untapped potential accountants possess to become indispensable partners in business growth and transformation. Discover how understanding business valuation and the eight key drivers can be the catalyst for both accountants and their clients to achieve extraordinary success while offering CFO and advisory services. If you're considering starting an accounting business, a bookkeeping business, or a tax business, or if you want to learn bookkeeping online and explore online tax courses, this episode is packed with valuable insights for aspiring entrepreneurs.   Sponsors: Universal Accounting Center Helping accounting professionals confidently and competently offer quality accounting services to get paid what they are worth.   Offers:   Now's the time to get your Business Score.  See how the 8 drivers mentioned in the show today apply to your business.  Learn what you can do today to work ON your business and improve your valuation to build the business you want.  CLICK HERE to start, it will only take 15 minutes.   It's time to compliment your accounting and tax services with quality CFO & Advisory services.  Become a Profit & Growth Expert, apply the Universal Business Builder principles with your clients and learn what you can do to be a Value Builder Provider.   Get The Unlocking Small Business Market whitepaper.  Understand how smart advisors position their services to protect, grow and realize the value of a business.  Learn what it is you can do to become an author, leveraging your expertise to market effectively your services and get the clients you deserve.  This is a webinar you don't want to miss.  Learn from Mike Capuzzi what a Shook is and how you can use it to position yourself as the Premier Accounting Firm in your area.  This is a must-see presentation so get ready to take some great notes.   In addition to becoming an author, see what you can do to follow the Turnkey Business plan for accounting professionals.  After more than 40 years we've identified the best practices of successful accountants and this is a presentation we are happy to share.  Check it out and see what you can do to be in business for yourself but not by yourself with Universal Accounting Center.   For Additional FREE Resources for accounting professionals check out this collection HERE!   Be sure to join us for GrowCon, the LIVE event for accounting professionals to work ON their business. This is a conference you don't want to miss.   Remember this, Accounting Success IS Universal. Listen to our next episode and be sure to subscribe.   Also, let us know what you think of the podcast and please share any suggestions you may have.  We look forward to your input: Podcast Feedback For more information on how you can apply these principles to start and build your accounting, bookkeeping & tax business please visit us at www.universalaccountingschool.com or call us at 8012653777

Leonard Zon '79, is the Grousbeck Professor of Pediatric Medicine at Harvard Medical School, an Investigator with the Howard Hughes Medical Institute, and Director of the Stem Cell Program at Boston Children's Hospital.

Synopsis: Sean Bohen, M.D., Ph.D., is the President and CEO of Olema Oncology, a biopharmaceutical company developing innovative targeted therapies for women's cancers. We're excited to welcome Sean back to the podcast – he last appeared on episode 130 in late 2022. Sean provides an update on all the exciting things that have happened at Olema since then, including an update on their lead product candidate. Sean reflects on navigating the challenging biotech market environment over the past year, making careful spending decisions, and raising significant capital to extend Olema's runway. He also offers advice to first-time CEOs on building a strong support network to guide company growth. Biography: Dr. Bohen has served as Chief Executive Officer of Olema Oncology and a member of the Board of Directors since September 2020. He is also a non-executive director of Gyroscope Therapeutics, Ltd. and AltruBio, Inc. He has extensive oncology drug development experience, having served as Executive Vice President, Global Medicines Development, and Chief Medical Officer at AstraZeneca PLC. Before that, he held a number of senior leadership roles at Genentech, Inc., including Senior Vice President, Early Development, Genentech Research and Early Development. Prior to Genentech, he was a Clinical Instructor in Oncology at Stanford University School of Medicine; a research associate at the Howard Hughes Medical Institute; and a postdoctoral fellow at the National Cancer Institute (NCI). Dr. Bohen received a B.S. in bacteriology from the University of Wisconsin-Madison, and a Ph.D. in biochemistry and biophysics and an M.D. from the University of California, San Francisco.

Dr. Kien Vuu, or "Doctor V," exemplifies resilience, having survived as an infant refugee on a challenging journey to America. Overcoming diabetes and high blood pressure, Doctor V now champions optimal health, happiness, and human potential making him a sought-after speaker and consultant by Fortune 500 companies, professional sports teams, and association meetings from all industries.  With tenure at UCLA, National Institutes of Health, and Howard Hughes Medical Institute, Doctor V is triple-board certified in Interventional and Diagnostic Radiology, as well as Anti-Aging and Regenerative Medicine. Founder of VuuMD Performance and Longevity, Doctor V advises athletes, executives, celebrities, and organizations towards longevity and peak performance. Doctor V is also the #1 best selling author of Thrive State, media expert, keynote speaker, and workshop facilitator at prominent events, including engagements with Whole Foods, Bank of America, and JP Morgan. He has also appeared on platforms like ABC News, TEDx, The Doctors, and Access Hollywood, empowering others to activate the biology of longevity and human potential within themselves. thrivestatebreath.com (free breathwork lessons and longevity & performance resources) thrivestatebook.com  Connect more with Dr Kien Vuu: Website: https://kienvuu.com/ Instagram: https://www.instagram.com/doctorvmd/ @doctorvmd YouTube: https://www.youtube.com/c/doctorvmd Trive State Book Link: https://www.amazon.com/Thrive-State-Performance-Longevity-Activating/dp/1950367568?asc_campaign=15060983bede4eb0aeb62a796f451943&asc_source=01GXEDNQWSQEH64QAKSMD5QY4E&tag=namespacebran417-20

Episode 121 Today we are joined by Dr. Chris Impey to talk about exoplanets, the search for life in space, and the search for meaning on Earth.   Dr Impey is a University Distinguished Professor of Astronomy at the University of Arizona. He has over 220 refereed publications on observational cosmology, galaxies, and quasars, and his research has been supported by $20 million in NASA and NSF grants. He has won eleven teaching awards and has taught two online classes with over 300,000 enrolled and 4 million minutes of video lectures watched. He is a past Vice President of the American Astronomical Society, won its Education Prize, has been an NSF Distinguished Teaching Scholar, Carnegie Council's Arizona Professor of the Year, and a Howard Hughes Medical Institute Professor. He has written 70 popular articles on cosmology, astrobiology and education, two textbooks, a novel called Shadow World, and eight popular science books: The Living Cosmos, How It Ends, Talking About Life, How It Began, Dreams of Other Worlds, Humble Before the Void, Beyond: The Future of Space Travel, and Einstein's Monsters: The Life and Times of Black Holes.    Support this podcast on Patreon at https://www.patreon.com/DowntheWormholepodcast   More information at https://www.downthewormhole.com/   produced by Zack Jackson music by Zack Jackson and Barton Willis    Transcript (AI Generated) ian (01:16.703) Our guest today is a university distinguished professor of astronomy at the University of Arizona. He has over 220 refereed publications on observational cosmology, galaxies, and quasars, and his research has been supported by $20 million in NASA and NSF grants. He's won 11 teaching awards and has taught two online classes with over 300,000 enrolled and 4 million minutes of video lectures watched. He's a past vice president of the American Astronomical Society, has been an NSF Distinguished Teaching Scholar, Carnegie Council's Arizona Professor of the Year, and a Howard Hughes Medical Institute professor. He has written 70 popular articles on cosmology, astrobiology, and education, two textbooks, a novel called Shadow World and eight popular science books. I'm very excited to welcome Dr. Chris Impey to the podcast today. chris_impey (02:07.898) Yeah, delighted to be with you. zack_jackson (02:09.75) Welcome. That's quite an introduction. Ha ha ha. Thanks for watching. I hope you enjoyed this video. I'll see you in the next one. Bye. ian (02:12.983) Yeah. Obviously, I shortened down what you sent us, and it was tough for me to do that, Chris, because you've done a lot. You know, obviously, I was at fellow academic. I understand the need to do peer-reviewed research and those types of things in our field, but I was really impressed with how much writing you've done for the general public, both articles and also your books. You've written a novel. You've been on several podcasts. Can you kind of tell us a little bit about your background, what is you do, and then how you also got into that part of your profession of making sure you communicate with the general public as well? chris_impey (02:53.298) Sure, you won't hear it in my voice, my accent, but I was born into Edinburgh, I'm a Scott. I had a little transatlantic childhood that sort of wiped out the Scottish borough, but if you feed me single malt whiskey it would come back. And of course, I'm sure you noticed if you've gone to Britain that you look up and there are not many stars visible there. So once I decided to do astronomy I knew I was going to leave, so I did my undergrad work in London. zack_jackson (03:04.15) Thank you. Bye. Ha ha ha! chris_impey (03:22.938) and never look back and I'm a dual citizen now. So astronomy is big in Arizona. I've not looked elsewhere. The grass is never greener anywhere else. We're building the biggest telescopes in the world and we have five observatories within an hour's drive. So this is the perfect place to do observational astronomy. So I'm very happy. But then as people's careers evolve, you know, the writing research papers is important. It's the sort of stocking trade of the academic. But it's also, you know, the texture of the average research article is that of a three-day old bologna sandwich. It's almost designed to be indigestible writing. The constraints of an academic discourse make that happen. So I was always interested in more popular writing, so I segued into textbooks. And then I realized the problem with them is that you've written a textbook and that's a nice challenge. But then the publisher just wants you to update it every year or so. It's like, okay, that's not so exciting. I think I'm not going to do this anymore. And then I think more broadly, apart from just liking education and being very committed to teaching and mentoring students, you know, I've just seen the, well, even before the sort of large waves of misinformation and the assault on facts in our culture, it's, I viewed it as an obligation of a professional scientist to communicate to a larger audience because, well, to be blunt, we're paid by the taxpayer. zack_jackson (04:26.05) Thank you. Bye. zack_jackson (04:44.15) Hmm. chris_impey (04:54.118) And also, there's a lot of misinformation out there, and science is often misperceived or characterized in wrong and inappropriate ways. And so I think all scientists should not just stay in their little lane doing research, but they should, if they can, some better than others. And not everyone can be Neil deGrasse Tyson. That's fine. But I think there's an obligation to communicate to larger audiences. And once I got into it and got practiced and better at it, then I now understand that I mean, it's like I couldn't imagine not doing it. chris_impey (05:32.018) And the books just, okay. And so books just flow out of that because writing popular articles is just a sort of lighter version of writing a technical article. And then, you know, you want a meaty subject. You do a book-length version. So I've been writing about cosmology and astrobiology. And I've started about 10 years ago I say, I think this is my ninth book, Exoplanets. So books are fun. They're more challenging. ian (05:32.543) I almost had to sneeze. Sorry, go ahead. Ha ha ha. chris_impey (06:01.958) to take on a big subject and distill it down and make it, you gotta make it, have a resonance for a person with no, maybe with no background in astronomy or maybe just a little background and you're taking them through what could be a very esoteric subject. So that, I like the challenge of that. Although the books are exhausting. Once I've done a book, I don't wanna, I almost don't wanna look at a book or read a book or write a book for a while. zack_jackson (06:28.65) do people ask you like when's the next one coming out? Like right after you finish. It's like having a baby. I'm not sure if you can tell, but I'm not sure. I'm not sure. I'm not sure. I'm not sure. I'm not sure. I'm not sure. I'm not sure. I'm not sure. I'm not sure. I'm not sure. I'm not sure. I'm not sure. I'm not sure. I'm not sure. I'm not sure. I'm not sure. I'm not sure. I'm not sure. I'm not sure. I'm not sure. I'm not sure. I'm not sure. chris_impey (06:31.898) Of course. Yeah, they are. Yeah, it's like I'm not going to go there about the having a baby because my wife would my wife would give me a hard time. There's nothing like having a baby. You can't even imagine, you know, and and and she and yeah, and she's right. But like having a baby, you know, women may feel that and then they do it again, you know, so I write the book, have have a slight, you know, trauma afterwards or just let down. It's a little bit of a let down sometimes. zack_jackson (06:43.89) That is a good man. Good job. ian (06:45.766) Yes. chris_impey (07:01.918) you finished any big-ish thing. But I do like writing, so I'm committed to it. zack_jackson (07:02.094) Hmm. ian (07:09.303) Yeah. zack_jackson (07:10.05) So you're writing and thinking and studying a lot about exoplanets these days. So you're writing and thinking and studying a lot about exoplanets these days. So you're writing and thinking and studying a lot about exoplanets these days. So you're writing and thinking and studying a lot about exoplanets these days. So you're writing and thinking and studying a lot about exoplanets these days. So you're writing and thinking and studying a lot about exoplanets these days. So you're writing and thinking and studying a lot about exoplanets these days. So you're writing and thinking and studying a lot chris_impey (07:15.718) Yeah, it's a super hot field with the number has up to 5,300 last time I checked on NASA's website. And remember, you know, 1995, the number was zero. So this is all, this is all the last few decades and it's just growing gangbusters. And now it's a slightly unfortunate because I have, we have students here who are working on exoplanets or astrobiology. And, you know, there was a time when if you discovered one cool Earth-like planet or water world, ian (07:27.244) I remember that. chris_impey (07:45.818) about it. Well now you know you'd have to find a hundred interesting things to write a paper. So the bar has been raised just by the success of the field. But the interesting thing is that it's moving to a new phase. So the most of what's known about those 5300 exoplanets is not much at all. They're basically is either a mass or a size or maybe both and you get a density and know it's a gas planet or a rocky planet. And that's it. We can't characterize zack_jackson (07:46.792) Hmm. zack_jackson (07:54.15) Yeah. zack_jackson (08:04.316) Hmm. chris_impey (08:15.698) thousands of exoplanets. So the next stage of the game, everyone's taking a deep breath in the research field is to try and characterize the atmospheres and the geology and of course find life. And that's just a very hard experiment. It's just much harder than detecting an exoplanet in the first place. So there's sort of excitement in the air because if I were betting, I would say that within five to seven years, we will have done the experiment of looking for life or Earth planets that are nearest to us and will either know the answer. Either there will be microbes on those planets that have altered their atmospheres or there won't be and that will be an amazing experiment to have done. So it's really on the horizon. But it's daunting because it's a very difficult experiment. Earth-like planets are a billion times fainter than the stars they orbit. So you have to, and they're far away so they appear very close to their star. So you have to isolate the planet from the star, blot out the billion times brighter and then smear the feeble reflected light from the exoplanet into a spectrum and look for molecules that indicate life like oxygen, ozone, methane, water vapor and so on. ian (09:26.503) But the molecules you're looking for are always in the atmosphere itself, right? Like you wouldn't, and I understand that, and I think we all do, but, you know, some people listening may not realize that that's, that's what you're looking at. When you're talking about with the spectrum is that makeup of the atmosphere, nothing about like if there's, if it's a rocky planet, what's on the ground, I guess. zack_jackson (09:26.614) Now. chris_impey (09:30.458) there. chris_impey (09:45.358) Right, right. And it's important for people to realize that the characterizing the exoplanets is done in that indirect way. For instance, of those 5,300, only 150 have ever had an image made of them. You know, seeing is believing. It's nice to have images of exoplanets. That's a hard thing. And those images are, you know, they're pathetic, a few pixels. They're just pale blue dots in a far away. So there's no, and if you ask this, ian (10:02.488) Right. zack_jackson (10:03.35) Thank you. Thank you. chris_impey (10:15.678) The question of when will we be able to make an image of an exoplanet to be able to see continents and oceans? The answer is maybe never. The answer is decades or a very long time because it's just too hard to make images that sharp of things that far away, even with space telescopes. So astronomers have to be a little more indirect and the clever method that's on the table now and will be done, James Webb is doing some of this but was never built to do this experiment, it will actually be better done with the huge... set of ground-based telescopes under construction. So the experiment is you use the star to backlight the exoplanet when it crosses in front of it, and the backlit, the light from the star filters through the atmosphere of the exoplanet and imprints absorption from these relevant molecules called biosignatures. So that's the experiment you're doing. And it's still hard. And it's also not clear you'll get an unambiguous answer. You know, obviously, and its cousin ozone are the prime biomarkers because on Earth, the oxygen we breathe, one part and five of our air, was put there by microbes billions of years ago. So the reverse logic is if you see oxygen on an exoplanet or in the atmosphere of an exoplanet, it must have been put there by life because oxygen is so reactive, so volatile that it disappears. If there's not life to sustain it, say the biosphere of the Earth shut down overnight, the entire biosphere just shut down. ian (11:41.803) Thank you. Thank you. chris_impey (11:45.458) just imagine the thought experiment. Within five to seven billion, a million years, so very short time in geological terms, the oxygen, that one part in five we breathe, would be gone. It would rust things, it would dissolve in seawater, it would oxidize with rocks, and it would be gone. So if it were not put there originally by life and then sustained by photosynthesis and other life processes, it would disappear. So the logic, therefore, is if you see it elsewhere, bang, it's got to be microbes putting it there and causing it to be there. ian (12:16.845) Yeah. zack_jackson (12:16.95) Hmm, unless there's some hitherto unknown non-living process by which these things happen. chris_impey (12:24.058) Right. So that's a good point. And there is a debate there because the data that's going to come in, well, first of all, it'll be noisy. It won't be beautiful, perfect spectra. So they'll be ambiguous to interpret. And then when you see it, what is the, where's, does the bar set for being enough? And the geologists have weighed in on this. And so whereas the sort of simplistic view as well, if you see any significant level of oxygen, certainly 18% like on the earth, what's got to be biology. zack_jackson (12:41.694) Yeah. chris_impey (12:54.218) That's pretty much true, but geologists have figured out ways where without biology, just with geochemical reactions, if you conjure up a geochemistry, you can get 6%, 5%, 7% oxygen. That's quite a lot, more than most people would have expected. So the geologists are saying, well, hold on. Yes, a lot of oxygen is probably a biomarker, but you would have to know more about the planet to be sure that it didn't have some weird chemistry and geology going on. for any of the other biomarkers. Methane is a biomarker too because it's produced on earth, you know, mostly by life, a good fraction of that, cow farts I think. But so it's the same argument. So these wonderful and difficult to obtain spectra are going to be, everyone's going to jump all over them and hope they give an unambiguous answer, but they might not. Science is not always as cut and dried as that at the frontier, which is where we are. But it's the zack_jackson (13:34.511) Hmm. Sure. chris_impey (13:53.958) exciting experiment and it will be done fairly soon. ian (13:58.804) Okay. chris_impey (14:01.358) And then a sort of related issue is that it's not just microbes. I mean, that's just looking for life as we know it on the earth. You could also look with the same technique, and this is an interesting possibility, for what are called techno signatures. So biosignatures is just evidence of life, typically microbes, because we think most life in the universe is going to be microbial, even if it's not exactly like our form of biology. But you could also look for things technology like chlorofluorocarbons, which you know, were responsible for almost killing the ozone layer for a few decades until we sort of ruled them out of refrigeration units. And there are other chemicals that are produced by industrial activity in a civilization, which would normally be very trace ingredients in an atmosphere, barely, you know, not present at all really. And if you could detect them in an atmosphere, it would be indirect evidence of a technological or industrial civilization. Realization on that planet and that will be very exciting. So that's the same method being used to ask a very different question But it's a more challenging experiment because these are trace ingredients. I'll give you an example I mean, we're all aware of climate change global warming and we've seen the carbon dioxide content of our atmosphere Increased by 30% roughly in the last few decades. That's quite a lot. It's obviously concerning and we know the implications But if you step back and look at the earth from afar and say, well, shouldn't that just be obvious? Shouldn't some other alien civilization look at the Earth and say, oh, those people are really screwing up. They're killing their atmosphere with climate change and fossil fuel burning? The answer is probably not because carbon dioxide is a trace ingredient of our atmosphere, and 30% increase on a trace ingredient would actually be very hard to detect from a distance. So even that dramatic thing that we are all anxious about on our planet industrial activity and fossil fuels is not dramatically obvious from a distance. So these are quite difficult experiments. The techno-signature experiment is much harder than the biosignature experiment. zack_jackson (16:13.592) Hmm. ian (16:14.165) Interesting. rachael (16:17.101) One of the things that you had said when looking at these exoplanets was, you know, we look at them and we want to see them and what's going on with them. And then you added the line, and of course, detect life. And that's where our conversation has gone for the last couple of minutes. But I'm wondering, you added that phrase that seems to think that finding life is part, entire reason for studying exoplanets. And I'm wondering, A, why you think that? And B, what that says about, you know, making it very narcissistic and Earth-centered, what that says about us. chris_impey (16:54.799) Mm-hmm. chris_impey (17:02.778) Right. Okay. So good question. I can unpack that in parts. I mean, yes, if I were a geologist or a planetary scientist, I'd be just pleased as punch and happy as a pig in a poke to just study exoplanets. That's all that I'm happy. I've got 5300 new, new geological worlds to study. Whereas the solar system only has a handful. Oh, yeah. So depending on your discipline, you might be totally zack_jackson (17:16.049) Hehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehe rachael (17:19.507) Right! chris_impey (17:32.718) properties. But astrobiology, I mean astrobiology writ large is the study of life in the universe, and the context for that search for life in the universe is the fact that we only know of one example of life, and that's on this planet. And everything in astronomy and the history of astronomy, and the Copernicus onwards, has told us we're not special, has told us there's nothing singular zack_jackson (17:59.891) Thank you. Bye. chris_impey (18:02.718) about our solar system, about our galaxy, or our position in the galaxy, and so on. In space and time, we are not special. And so, you know, for biology to be unique to this planet, when the ingredients are widespread, we've detected carbon, nitrogen, oxygen, the biogenic elements out to distances of 12, 13 billion light years, almost to the birth of the universe. Water is one of the, you might think it's special. Earth is a water world. Well, actually, some of the exoplanets have 10 to 30 times more water. water than the Earth. So it's not, the Earth isn't really a water world even, pale blue dot, it's not that special. And water is one of the most abundant molecules in the universe too. So all the ingredients, the table is set for life in the universe. And as the universe is evolved and is quite old, more and more of those biogenic elements are made by stars and spat out into space to become part of new star systems and planets. And so in an old mature universe with a lot of heavy elements, and with many habitable locations now, we the best guess is 20 billion Earth-like habitable worlds just in our galaxy, then it just, whether or not it's central to astrobiology, it absolutely begs the question, is biology unique to this planet? Because it really shouldn't be statistically. However, logically, you know, to be correct and scientific, it's possible that there were a unique set of accidents and flukes that led to life on Earth, and it is unique. It would still chris_impey (19:33.038) It's historical science to wonder how life on earth developed and nobody's ever built a cell from scratch in the lab people have done various parts of that experiment and They can't connect all the dots, but they've done some very interesting experiments that certainly suggest It's not a fluke that the whole thing happened. You need time. You need the possibilities of Chemicals bumping into each other and getting more complex, but that tends to happen It happens if you do it in a computer it in a lab as well as you can. And so the context of the ingredients for life being so widespread and there not seeming to be any sort of bizarre, flukish occurrence in the development of at least replicating molecules that could store information, if not a full cell, would certainly lead you to anticipate life elsewhere. And then game on, because the big question then is, so there are two almost binary questions you're trying to answer, which is why the field is so exciting. Is there life beyond Earth, yes or no? And then if yes, is it like our life? Is it biology? Because everything on Earth, from a fungal spore to a butterfly to a blue whale, is the same biological experiment. They seem like very diverse things, but that's one genetic code. experiment that led to that diversity after a long time, after four billion years of evolution. And there's no reason to expect, even if the ingredients for life and the basis for biology exist far beyond Earth and in many locations, there's no real reason to expect that it would play out the same way elsewhere. And so that second question, is it like Earth life, is a very big question. rachael (21:27.201) Just as a curiosity, when did, if you know, when did microbes appear on Earth? chris_impey (21:39.158) So the earliest, the indications of life on Earth, the history of that is really tricky, because as you know, the Earth is a restless planet, and we weren't there, it's historical science, and it's possible you may never answer the question, but the big problem is the restless Earth. It's very hard, there's only a handful of places on Earth, Western Australia, Greenland, somewhere in South Africa, where you can find four billion year old rocks. They just don't exist. I mean, everything's been churned by geology and eroded rachael (21:46.661) We weren't there. Yeah. Yeah. Yeah. rachael (21:56.104) Right. chris_impey (22:09.338) Weathered and so on so just even and that's about when we think life started So you're dealing with you know a crime scene where the evidence has been trampled many times and the crowds have just Obliterated the evidence so that's a hard thing and then the second hard thing is that the incipient Traces of life as you get to cells are very indirect They're sort of just you they're biochemical tracers or sorry there. They're chemical imbalances isotopic imbalances of versus normal carbon and so on. Because you're not looking for fully fossilized cells. So if you're just looking at what would be called chemical tracers of life, they're pretty good, but argumentative, this field is not resolved, traces that go back about 3.8 billion years. If you're asking when do you have the first fossil life forms, fossilized microbes, single cells, rachael (23:00.421) Okay. chris_impey (23:09.238) to 3.4, 3.5 billion years, and that's people then stop arguing about it. I think they believe that evidence. And then there's this enormous long time between that and multi-celled organisms. That step in the evolution of life seems to have taken a long time. You could infer that that means it's difficult or doesn't happen very often, but that's a dangerous inference from data of one. All the inferences, hazardous. So astrobiologists have to keep pinching themselves and saying, it's a sample of one. It's a sample of one. rachael (23:30.921) Thank you. Thank you. zack_jackson (23:32.75) Thank you. Bye. rachael (23:39.721) One does not make a line. One day to... That's right. That's right. That's right. That's right. That's right. That's right. That's right. That's right. That's right. That's right. That's right. That's right. That's right. That's right. That's right. That's right. That's right. That's right. That's right. That's right. That's right. That's right. That's right. That's right. That's right. That's right. That's right. chris_impey (23:41.139) Don't draw too many conclusions. So, yeah, the cell formation, the evolution of the first cells and microbes seem to have taken 300 or 400 million years from the first chemical traces of life. But those chemical traces, we don't know. There's that Zircon that was found in Western Australia, 4.404 billion years accurately measured by radioactive dating. chris_impey (24:09.378) environment and so there's evidence really soon after the earth formed when it was just a hellhole of a place you know impacts and craters and geological activity that the earth surface was almost tacky like magma and yet there were there were any ingredients for life there so nobody would rule out life going back very close to the formation of the earth but then but tracing all these evolutionary paths is really hard I mean we have stromatolites which are modern descendants of the first microbial colonies. You can go to Western Australia, Shark's Bay, I've been there and it's great, they're stromatolites. These were just the same as they were now three billion years ago, it's really cool. One of the things you can't see behind me is my stromatolite collection. rachael (24:53.985) Yeah. rachael (24:59.962) One of the reasons, yeah, that's fascinating. It makes a collector about that. It makes a collector. Um. Yeah. zack_jackson (25:00.071) kind of a few collections chris_impey (25:01.578) Yeah. Oh, well, three. Does that make a collection? ian (25:05.749) It's good enough. chris_impey (25:07.958) Well, yes. It's like primitive counting systems, one, two, many. So I have many. I have many. I have many. I have many. I have many. I have many. I have many. I have many. I have many. I have many. I have many. I have many. I have many. I have many. I have many. I have many. I have many. I have many. I have many. I have many. I have many. I have many. I have many. I have many. rachael (25:13.941) That's right. zack_jackson (25:15.016) Ha! rachael (25:19.021) One of the reasons I was asking that question about Earth, because you were talking about these very far away planets and looking for microbial, likely microbial life, then showing up in the atmosphere by its various products. And so my question was stemming from how far back are these planets that we're looking at? a really long time to create its microbes, then perhaps, since we're looking so far back in time, that maybe those microbes exist now, but when we're looking at them, they didn't exist. Right, that lovely time, space question. chris_impey (25:51.579) Mm-hmm. chris_impey (26:02.098) Right. So in that context, it's important to say that the exoplanets we're finding are in our backyard. So Kepler, NASA's Kepler mission is really responsible for almost half the exoplanets, even though it stopped operating a few years ago. And so the most exoplanets we know of are within 100 to 1,000 light years. And that's our backyard. The Milky Way is 100,000 light years across. rachael (26:12.785) Okay. rachael (26:28.064) Oh, close. Yeah. chris_impey (26:32.398) And of course, logically, therefore, we're only seeing them as they were a century or millennium ago, which is no time geologically. So we can't see that far back. So we're not really looking at ancient history. However, the more important point, having mentioned that carbon nitrogen, oxygen, and water have been around in the universe for a long time, is that we now can very confidently say, even if we can't locate such objects, that an earth clone, rachael (26:32.606) Okay. rachael (26:38.901) Yeah, it's no time at all. Yeah. chris_impey (27:02.098) something as close to Earth as you could imagine, could have been created within a billion years of the Big Bang. And that's seven billion years before the Earth formed. So there are potential biological experiments out there that have a seven billion year head start on us and then add the four billion four and a half billion years of evolution. And that's boggling because you know, we can't imagine what evolution and biology might come up with given 10 or 12 billion years to evolve rather zack_jackson (27:11.75) Hmm. chris_impey (27:31.958) Maybe it makes no difference at all. Maybe these things are slow and they're hard and the Earth was actually one of the fastest kids on the block rather than one of the slowest kids on the block. We don't know. Sample of one again. We'll just put that as a big asterisk over almost everything I say so I don't have to keep saying sample of one. Okay. zack_jackson (27:32.014) Hmm. rachael (27:41.861) Simple of one. zack_jackson (27:42.808) Yeah. zack_jackson (27:48.834) No. rachael (27:49.221) That'll just be today's episode title, right? Today's sample of one. Okay. Okay. Okay. Okay. Okay. Okay. Okay. Okay. Okay. Okay. Okay. Okay. Okay. Okay. Okay. Okay. Okay. Okay. Okay. Okay. Okay. Okay. Okay. Okay. Okay. chris_impey (27:51.14) Yeah, right. zack_jackson (27:52.65) That's Apple F1. chris_impey (27:55.038) Yeah, induction is a bitch when you can't do it. zack_jackson (27:55.492) So. zack_jackson (28:02.51) So we've talked a lot about the how it's possible, how we might detect it, but what do you think it might do to our sense of self and our sense of spirituality, our sense of humanity, our sense of earth? Should we start discovering life outside of, or at least biological markers in other places? chris_impey (28:28.898) Right. I mean, I think it sort of bifurcates if we find microbial life elsewhere and improve it, you know, it's beyond a reasonable doubt. And even if we don't know if it's our biology or not, it's just a biomarker that's irrefutable or set of biomarkers. That will be a transformative, epochal event in the history of science. It'll be dramatic. But it will make front page headlines and then fade, I would say, fairly rapidly, because it's microbes. zack_jackson (28:44.618) Mm-hmm. chris_impey (28:58.858) Like, that's Ponskum or stuff on your shower curtain, like, okay, who cares? So, I mean being facetious, but not too facetious, because I think the public will just be interested and science interested people will be very interested, and books will be written, and documentaries will be made, and so on. But in the public consciousness, I don't think it will permeate very far or persist very long. Of course, the counterpoint of if we decide we found intelligent life in the universe through those techno markers. zack_jackson (29:03.391) Ha ha ha. chris_impey (29:28.978) you know, the search for artificial radio or optical signals from some civilization. So they're obviously artificial and they couldn't have been produced by nature. That will be more profound, of course, because that's companionship in the universe. And that will raise all sorts of questions. So I think it really divides that way. And since the universe logically, if life exists in the universe elsewhere, there'll be many more microbes than intelligent civilizations. You know. ian (29:29.523) Mm-hmm. chris_impey (29:58.858) seed in that first mode. Although SETI is a side bet. I mean SETI for 65 years has been placing this little side bet. Okay, yeah, we can look for microbes and those are hard experiments and now we can almost do it. But let's always place this side bet of jumping over the evolutionary path from microbes to men or humans and look for those intelligent technological civilizations directly. And so it's worth doing. I'm not science scientists are divided on SETI, even astronomers are divided on it, whether it's a worthwhile pursuit or not, whether it's even scientific or not. That's the strongest critique of SETI is that unlike, you know, if I wanted to go to the National Science Foundation and get a million dollar grant to study some issue of, you know, solid state physics or high energy physics, I'd have to propose an experiment and define my parameters and how I was going to control variables and say how I would interpret the data. could refute or confirm. SETI doesn't have that kind of situation. They don't know how to define success or failure even. Well, they can define success more or less, but they can't define failure and they can't say what the probability of success is. So it's not a normal scientific pursuit. So that's the critique of SETI from scientists, but I still think it's worth doing. ian (31:04.946) Right. ian (31:23.628) Yeah. rachael (31:24.842) You talked about, and I think you're probably right in terms of how much people will care in the long run or in their day-to-day life or, right? Okay, so we found some microbes from, you know, a thousand light years away. I don't, that didn't reduce my student loan at all. But like, didn't, thank you. It's nice, saw the headlines. It's now three years later. chris_impey (31:45.018) Right. rachael (31:54.441) But I've noticed that you did a lot of work with the Vatican and with monks, and I think that that's a different population that might respond to and other religious figures, but specifically those I'm asking you because those are the groups that you've worked with. They might respond a little bit differently to this existence. Could you speak a little bit ian (32:01.35) Yeah chris_impey (32:16.803) Right. rachael (32:23.726) in this idea of how it would change. chris_impey (32:25.658) Sure. And maybe preface it with just the cultural comment, with independent religion, that the other issue that will arise with, I mean, if microbial life is found elsewhere and astrobiology is a real field with the subject matter, finally, yeah, it's foundational for science. And of course, it terraforms biology because, you know, if you want to poke, if physicists want to poke at biologists who say, well, you just spent your whole life studying one form of biology, What about all the other forms? You don't have a general theory of biology like we have a standard model of particle physics because you've just been studying one thing like staring at your navel. Well, what about all that stuff out there? Okay, so so it'll be a big deal for biology for all of science but on the intelligent life or advanced life, the problem with what happens outside the scientific community is it's not a tabula rasa. It's not a blank slate. The popular culture, especially in the US ian (32:59.524) Hmm. ian (33:08.503) Thank you. Bye. chris_impey (33:25.718) but almost everywhere now, is so primed for the fact that, A, it's already there and sure, and B, it's visited, and three, it's abducted some of our people, and four, it can make a list of all the conspiracy theories and wild ideas about alien life. And they're just so embedded in the popular culture that it's like that the fact of the existence of intelligent aliens has been amortized. It's sort of been, it's just already been built in. zack_jackson (33:39.8) Thank you. chris_impey (33:55.698) in to the culture. And so, you know, that would lead to a collective shrug. Well, sure, we knew that, you know, the government's been hiding this stuff from us for 70 years, since Roswell. So, you know, and now your astronomers are coming along and telling us, oh, it exists and you're all excited, really? Oh, come on, you know. So I think that's the larger cultural issue or problem or whatever, it's not a problem, it's just amusing to me. But as far as a religious reaction to this, and I'll say, zack_jackson (34:02.271) Hmm. rachael (34:04.421) Thank you. Bye. zack_jackson (34:05.05) Thank you. Bye. zack_jackson (34:12.722) Ha! chris_impey (34:25.698) the gate that I'm an agnostic, which my wife's a pretty hardcore atheist. And so she gives me a hard time about being agnostic. She thinks that's a kind of, it's a kind of wussy position to take. But I, and I argue with her, we argue vigorously about that one. I argue with her and I use the phrase that was attributed to Feynman. And I think he did say this in the biography of Richard Feynman, famous physicist. His biographer said, zack_jackson (34:43.45) Fantastic. chris_impey (34:55.738) Feynman believed in the primacy of doubt and that he held as a high scientific mark and doubt skepticism and doubt is a is a very high mark of a scientist. So I'm proud to wear that mantle of skepticism doubt of not being sure and being okay with not being sure. So I'm an agnostic but I do keep bad company and some of that bad company is Jesuits. Don't you know, don't don't go drinking with Jesuits. You'll you'll you'll end up in a rachael (34:59.461) Thank you. Bye. ian (35:13.024) Right. zack_jackson (35:14.092) Yeah. chris_impey (35:25.798) and a Rome gutter somewhere and they'll be they'll have got back home safely. With the Buddhists, the other group I hang out with, you don't have to worry about being drunk in a gutter because they really don't drink. They do bend the rules a bit, you know, I've seen them eat a lot of meat for people who are supposed to be vegans and vegetarians. But anyway, those are the two tribes that I've sort of affiliated myself with. And their reactions or perspectives on life in the universe is are quite different. They're interesting. Each the Buddhists that I've been with and I've read behind this of course and read some of their More you know the scholarly articles written about this It is completely unexceptional in their tradition to contemplate a universe filled with life That could be more advanced It could be human like or it could be more advanced or different from humans in also a vast universe with cycles of time and birth and and death of the universe and rebirth of other universes. So the Byzantine possibilities of life in the universe are pretty standard stuff for them and would not surprise them at all. They do get into more tricky issues when they come to define life itself, which biologists of course have trouble with, or sentience, which is also a tricky issue. But on the larger issue of the existence of life in the universe far beyond Earth, that's just non-controversial. zack_jackson (36:48.35) Hmm. chris_impey (36:55.898) to them and when I say that's what we anticipate and that's what scientists expect it's like okay sure and the Jesuits are in a different slightly different space they're of course in an unusual space as we know within the Catholic Church because they're you know they're the scholarly branch you know they're they're devoted to scholarship they from Gregory and the calendar reform they were liberated to measure ian (37:17.944) Mm-hmm. chris_impey (37:25.678) the heavens and then eventually that just segwayed smoothly into doing astronomy research. The Jesuits have been doing pretty straight up astronomical research since certainly the early 19th century, so quite a long time. And they have that sort of intellectual independence of being able to pursue those ideas. All the Jesuit astronomers I know, there are I think 11 or 12 in the Vatican Observatory and they all live the double life. They're all PhD astronomers. rachael (37:37.221) Thank you. chris_impey (37:55.798) with parishes. So it's not a problem. Whoever else, whoever elsewhere might think there's a conflict between science and religion, they don't see it. They don't feel it. And if you ask... Yeah. Yeah. ian (38:05.145) Mm-hmm. zack_jackson (38:06.03) No. And if anyone out there wants to hear more about that, they can listen to episode episode 113 with brother guy, the, uh, the director. Yeah. ian (38:10.246) We have an episode. chris_impey (38:13.821) Right. ian (38:15.343) Director of the Vatican Observatory. chris_impey (38:16.418) Sure, sure. So I've known guys since, well, since he was a grad student actually, and a long time. And yes, and so they, they're pursuing it from a scholarly direction. And for them, it's also uncontroversial that there would be life elsewhere. Now, what is the, you know, what does that do to God's creation when you imagine that Earth and humans are no longer the centerpiece of it? That's a more interesting question. zack_jackson (38:22.034) Wow. chris_impey (38:46.298) I've had debates about that. And I heard Jose Funes, who was the previous director of the Vatican Observatory and Argentinian astronomer, in a press conference actually in the Vatican City State when we had a conference on astrobiology. In response to a question about astrobiology, because that was what the conference was about, he gave a very interesting answer. He said he gave a parable of Christ in the flock of sheep and how there was the sheep that was lost. you know, you had to gather back to the rest of the flock. And he didn't complete the story, he just left it hanging there. And so you were left wondering, are we the lost sheep, you know, and the other, and all the intelligent aliens out there are the rest of the flock? And what's the message, you know? So he sort of almost muddied the waters with his little parable. But in the manner of how they view the universe, zack_jackson (39:27.914) Hmm. rachael (39:28.621) Thank you. Bye. zack_jackson (39:33.792) Hmm. chris_impey (39:46.398) the rules of physics. I used to teach a team graduate cosmology with Bill Staker, who is one of their tribe. Sadly, he died a few years ago. We teach cosmology and he's a relativist. He works on general relativity and the Big Bang and all that. And if I was just wanting to pull his leg at breakfast, we had breakfast before we taught us to organize ourselves. I could do one of two things. I could say, oh, Bill, physics, we got you with physics. is squeezed back to the first 10 to the minus 43 seconds. Got to the gaps, there it is, that's a little gap. And then physics owns the rest, you know. And then if I was really feeling frisky, I'd sort of, since he was a Catholic, I'd tease him about the three impossible things he has to believe every morning before breakfast. Virgin birth, resurrection, et cetera, you know. So I don't know how all those circles are squared truly because we've had, you know, I've had conversations. zack_jackson (40:22.572) Hmm. zack_jackson (40:26.32) Hehehehehe zack_jackson (40:35.05) Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. Thank you. chris_impey (40:46.798) But I know that it's not a conflict or a tension or even a problem to imagine life in the universe and even intelligent life. So for neither of those two very different religious tribes, does it seem to be an issue? ian (41:06.443) So can you talk more about, especially how you got involved? Cause I think that science for the monks and nuns program was really interesting. And, you know, one, how you got involved, but you know, reading your book Humble Before the Void was just very interesting to kind of see about your experience from there. And you told us before we started recording that you wrote that after your first time going and that you've been there eight or nine times now. What has all of this been like for you? How has it had an impact on your work and also your personal life? if yes and what ways. chris_impey (41:38.798) Yeah, it was a sort of profound, it's been a profound experience since 2008, I guess, so it's almost 15 years and eight trips. So the first time was one of those great things of you come across the transom professionally. Sometimes I got a call from a colleague that I didn't know that well, who he knew I had an education, a good reputation as an educator. And he just called me, he's a postdoc at Berkeley actually, an environmental science postdoc. He said, how'd you like to go and teach the Dalai Lama's monks cosmology? And it's not a question you ruminate over or look at your skit, look at, oh, I'll check my calendar. Let me get back to you. No, you just say yes, and then you make it happen. So I said yes, and then it happened. And I was savvy enough in hindsight to take my 17-year-old Paul with me on that trip. And he'd never been anywhere out, he'd been to Europe a couple of times, but he'd never been to Asia or anywhere exotic. zack_jackson (42:14.65) Ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha rachael (42:17.821) Ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha zack_jackson (42:23.05) Thank you. Bye. chris_impey (42:38.738) if you like. And so that was a profound trip in that sense. It was a bonding with your 17-year-old and you know, we were a little more adventurous together than either of us might have been on our own. And so the context was that invitation. And then I learned that his holiness the Dalai Lama, who famously has said in his autobiography that if he hadn't been selected at age four to be the of compassion would have been an engineer. Fine, that's an interesting statement to make. But, and it meant that when he was a child in Eastern Tibet, in a pretty primitive village, you know, he would just infuriate his parents by taking apart their clocks and mechanical devices and never quite putting them together again. So he had this analytic and mechanical and engineering and scientific mindset even as a child. And then of course his future was cast into the role he had zack_jackson (43:11.134) Hmm. zack_jackson (43:25.992) Hmm. chris_impey (43:38.798) he took. But he's always had that strong interest in science. So he looked around 20 or so years ago and realized that the monastic tradition, his, the Gelug tradition, of course, or other traditions in Buddhism, was sort of outdated. You know, the monastic training was extremely rigorous. They take years and years of rhetoric and philosophy and theology and comparative religion and all sorts of things. But there's very little science, very little math. And in the schools, there's zack_jackson (43:39.972) Bye. chris_impey (44:08.718) very little science and very little math. And he just thought that was unacceptable. He said, my monks and nuns, the nun part actually did come later. And that was a good part of his work to make the level of playing field for monastic training to include nuns. But he just said, these my monastics cannot be prepared for life in the 21st century if they don't have science and math. And so in the manner that he does these things, he just looked around and waved his arm and said, make this happen, you know, and I've now zack_jackson (44:19.05) Thank you. Thank you. zack_jackson (44:30.035) Yeah. zack_jackson (44:37.45) Hehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehehe chris_impey (44:38.798) heard from proximity to people in his orbit that his holiness, the Dalai Lama says a lot of things. He has great ideas. He's very activist. He's very visionary. And he says all sorts of things. And people scurry around and sometimes they just ignore him. Sometimes nothing happens. But this one, they decided to make it happen. And what happened was they looked around Dharamsala chris_impey (45:08.658) the blue, who was an educator and a scientist, a young scientist. And they just glommed on to him and they said, Hey, can you help us with this? Can you set something up? And so he set up the science for monks program, then science for monks and nuns. When the nuns came on board and I was one of the early people he called. And so the model was to bring three to four Western teachers in different subjects. The Dalai Lama's core interest. it doesn't mirror a bit his interests, which are evolutionary biology, neuroscience, physics, math, and then environmental sciences come on board too. So it's not every field of science. So these, we would come out as Western teachers and there'd be cohorts of monks and then monks and nuns, about 24 in a group. And we do three week intensive workshops and they're very intense, you know, we're in the classroom six, seven hours a day and then our evening sessions or observing zack_jackson (45:50.671) Hmm. chris_impey (46:08.658) telescopes. So it's kind of grueling actually, but it's inspiring as well. And eventually, the idea is that enough of the monks and nuns will be trained to be educators themselves, and you won't need to depend on Westerners to come out and do this. And they're not really there yet, but they could get there. I don't want them to get there, because then I won't get invited out. So it was a singular experience. And the book I wrote, of course, was fresh, zack_jackson (46:24.494) Hmm. chris_impey (46:38.738) I was really, I wrote it not long after the first trip. And to your question of did it affect me or change me? Well, yes, in many ways, some of which I probably haven't fully appreciated. I mean, first of all, it was a deep embedding in a culture, in a way that I'd never done. I was pretty experienced world traveler, but in that sort of slightly superficial way of someone who goes to Asia and tries to hang out and go to a bar in a local restaurant and see the sights, but you don't really get to know the people ian (47:05.228) Mm-hmm chris_impey (47:08.838) you're moving around. So being three weeks, sometimes four weeks, and then traveling with them afterwards or during, you know, really you get to learn the culture. You also see in these northern Indian towns, most of the workshops are in northern India, there's now in southern India, Bidtabhatta, Nepal for this too. They're mixing very well. India has a, you know, kind of black mark on it right now with its current government of sort of sectarian strife and Most recently with the Sikhs, but also obviously with Muslims But in those little northern Indian villages where there are sometimes 50 percent Buddhist 50 percent Hindus They really get on pretty well. I mean that they're just they're sort of under the radar the geopolitics or the What the Modi government is doing at the time so? It works pretty well, and it's nice to see that So I learned that I saw the culture up close. I would be part of their rituals and go, you know and ian (47:50.666) Mm-hmm. chris_impey (48:08.758) see everything they saw and listen to their prayers and talk to their scholars. And so it was a pretty deep embedding. And then as far as my own life, when I come back, rather than just view it as, you know, amazing experience, I got some beautiful photos. I had these great memories. Um, it did sort of make me reflect a little, uh, because of their, the ethos they had. And their ethos is, is of course very, um, very different from most of a Western ethos. It's a Buddhist are all about compassion and suffering, suffering and compassion. They do go together. They're almost bedfellows. So I got the message, I think very early on, when I was walking towards the lecture hall and it was at one of these Tibetan children villages and they're very poignant places. They're about 11 or maybe now 14 Tibetan children villages in the northern part of India. And that's where the refugees go. ian (48:46.008) Mm-hmm. chris_impey (49:09.158) that escaped. So almost all the monks in my early workshops left Tibet when they were teenagers even younger, brought across the ice fields by family members at great risk. Some didn't make it, others lost toes and fingers from frostbite. They had to go in the winter because the Chinese troops would intercept them and even even then did in the winter. So they were orphans, And they grow up and go to these Tibetan children villages, sort of orphanages, really. And so I was walking towards the lecture hall, which is situated in one of these villages. And there was a hard, scrabble, packed dirt soccer pitch. You know, it looked really uncomfortable for falling. I am enough of a Brit to have experienced playing football soccer on really nice grass, because England does have good grass, you know. And I was thinking, the first thing I thought, damn, I don't want to play football. rachael (50:04.321) Ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ian (50:04.525) Right. zack_jackson (50:05.412) Hmm chris_impey (50:08.918) on that field. That would be brutal. So there was this football field and there was a 10-foot wall behind it running the length of the football field, painted white, and on top of it in 10-foot high letters was a slogan of the school, others before self. And I was just thinking, I wonder how many American high schools would have that as their slogan. How would that go down with the, you know, social media, me generation, whatever. rachael (50:10.621) Ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ian (50:31.167) Right. rachael (50:31.321) Ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha ha zack_jackson (50:32.25) Hmm ian (50:34.845) Yeah. chris_impey (50:38.918) So that was one thing. And then a series of those little messages sort of sink in about how they do operate differently from us or me. And so one thing it made me reflect on when I went back home was I immediately embedded back in my academic life and hustling the next grant and writing the next paper and talking to my collaborators. And I just realized how really how intensely pressured. rachael (50:40.763) Wow. chris_impey (51:08.658) Darwinian that science, Western science system is, it's kind of, you know, it kind of grinds you down. I mean, I've been hustling for grants from funding agencies for 40 years and I kind of burned out on it, you know, it's hard. It doesn't get any easier because there's younger whippersnappers that are very smart and, you know, they're going to get your grant. So it definitely made me reflect on the sort of hyper competitive nature of some parts of zack_jackson (51:21.042) Hmm. ian (51:21.047) Mm-hmm. rachael (51:28.721) Thank you. Bye. chris_impey (51:39.719) and just reflect on what is important. Is it important to know something, or to teach something, or to give something, or to what is important? And how does that work when you're a scientist and educator? And that's it. Thank you for watching. I hope you enjoyed this video. I'll see you in the next one. Bye. ian (51:56.043) Yeah. Well, it's just interesting reading the book and I told you before we're recording. I've not been on to finish it yet, but I look forward to finish it just because, you know, one, you know, as I've already said, you're a fantastic writer for the lay audience, the general public, which is not something, you know, I've, I've worked with many scientists as a science educator and many of the ones I've worked with have said they struggle with that. Right. So I always applaud that. Um, but then just the, the personal experiences you shared and. chris_impey (51:59.833) I'm ian (52:26.163) humble before the void was just very interesting to me, especially someone who I have embraced meditation and mindfulness over the past three or four years and gotten really into it. And so, you know, first when I, when you shared that book with us and saw that the Dalai Lama wrote, you know, the preface for it and everything, I just was immediately fascinated because I find him to be absolutely fascinating in his perspective on things. So chris_impey (52:47.298) Yeah, I mean, I was, I mean, I've been privileged to meet him a couple of times. And, uh, and it's always, uh, a singular experience. Uh, the first time was that first trip out actually. And, and it was in that same Tibetan children village. And that was, this was in the winter. I was a January is a very, um, very difficult time to be there. It's in the foothills of the Himalayas. Quite high up. Dharamsala has trivial factoid that a Brit will appreciate like me. Um, It has the world's highest cricket stadium. And so drum solo, there you go. Now you know, when you get asked that, now you know. So we were in this auditorium, this cold auditorium, very cold, and they'd given the Westerners blankets, put over their legs, and even a few little heaters around. But it was brutal. And he was going to give an opening address. And everyone was full of excitement and anticipation. It was probably 2,000 people. But it was a cold, it was an unadorned Spartan auditorium ian (53:20.331) Oh. zack_jackson (53:20.594) Hmm. Ha ha ha. ian (53:25.403) Exactly. zack_jackson (53:34.892) Hmm. chris_impey (53:47.498) on a below freezing day in the Himalayas. And along that football field outside, which is the way his little, he has the equivalent of a pokemobile, he has the DL mobile or whatever that he comes into a place with, that he was gonna come along the edge of the field. And I'd seen walking in that the school children were starting to assemble in a long row along the side of the football field along the place his vehicle would come. And we were waiting zack_jackson (54:01.775) Thank you. Bye. chris_impey (54:17.258) He was late and it was so cold and it was quiet. People were murmuring, nothing was happening. And then suddenly we heard this sound, this wave of singing. So they were singing him in as his vehicle arrived. And I was like, wow, that was so cool. Just the sound of that. And then he came and he just radiates when he's in a room. And he's a little frail. He had trouble getting up the three steps onto the stage. But his grin is just... Oh, it's just... anyone who remelt the hardest heart. He's just so... and his comments are always, you know, they're always kind of offhand and insightful and, you know, he has a very interesting and sensibility. So that's been a remarkable thing. But the monks all had their own insights and I learned a lot from them. I mean, I was teaching them but I was learning a lot from them. And they gave me, you know, when you teach, well, the other thing I didn't say about the ian (55:12.667) Mm-hmm. chris_impey (55:17.418) experience there, which was also restorative for me, is, you know, I depend on my high tech gadgets and my PowerPoints and my whatever. And I was pretty much warned. I said, you're going to be pretty much off the grid. And it was almost like that. And there were a couple of workshops where, you know, if the cold water, if the water was hot, you were lucky. If the power stayed on all day in the classroom, you were lucky. There was hardly any equipment. We make these, these runs rachael (55:25.325) Hmm. chris_impey (55:47.278) These equipment runs down to the local bazaar, and we buy matchsticks and cloth and cardboard and foil and just super primitive ingredients to make experiments back in the classroom, rather than bring stuff out from the West. So you had to improvise, and it was good to do that. It was good to have to lecture and talk and use simple analogies and simple equipment. And so they informed me about that, too, because I wondered how they understood zack_jackson (56:02.75) Thank you. Bye. chris_impey (56:17.278) these very abstract things of physics and cosmology. And I think the first striking little insight I had, because I was always reaching for a good analogy. And then, so I sort of turned the tab

Dr. Siwei Lyu, SUNY Empire Innovation Professor at the University at Buffalo Dr. Siwei Lyu received his B.S. degree (Information Science) in 1997 and his M.S. degree (Computer Science) in 2000, both from Peking University, China. He received his Ph.D. degree in Computer Science from Dartmouth College in 2005. From 1998 to 2000, he worked at the Founder Research and Development Center (Beijing, China) as a Software Engineer. From 2000 to 2001, he worked at Microsoft Research Asia (then Microsoft Research China) as an Assistant Researcher. From 2005 to 2008, he was a Post-Doctoral Research Associate at the Howard Hughes Medical Institute and the Center for Neural Science of New York University. Starting in 2008, he is Assistant Professor at the Computer Science Department of University at Albany, State University of New York. Dr. Lyu is the recipient of the Alumni Thesis Award of Dartmouth College in 2005, IEEE Signal Processing Society Best Paper Award in 2010, and the NSF CAREER Award in 2010. He has authored one book, and held two U.S. and one E.U. patents. He has published more than 50 conference and journal papers in the research fields of natural image statistics, digital image forensics, machine learning and computer vision. For links and resources discussed in this episode, please visit our show notes at https://www.forcepoint.com/govpodcast/e260

Dr. Kien Vuu or "Doctor V", illuminates us on how out Default Mode Network (DMN) is impacting our epigenetics, and how breaking from our old programming can free us (and free our DNA) to reach a state of health and harmony, thus bring about longevity.Doctor V exemplifies resilience, having survived as an infant refugee on a challenging journey to America. Overcoming diabetes and high blood pressure, he now champions optimal health, happiness, and human potential, making him a sought-after speaker and consultant by Fortune 500 companies, professional sports teams, and association meetings from all industries.With tenure at UCLA, National Institutes of Health, and Howard Hughes Medical Institute, Doctor V is triple-board certified in Interventional and Diagnostic Radiology, as well as Anti-Aging and Regenerative Medicine. Founder of VuuMD Performance and Longevity, he advises athletes, executives, celebrities, and organizations toward longevity and peak performance. Doctor V is also the #1 best-selling author of "Thrive State," as well as a media expert, keynote speaker, and workshop facilitator at prominent events, including engagements with Whole Foods, Bank of America, and JP Morgan. He has also appeared on platforms like ABC News, TEDx, The Doctors, and Access Hollywood, empowering others to activate the biology of longevity and human potential within themselves.In this episode, we cover practical steps that can help us loosen the grips of DMN, how to discern if your life decisions are made from ego vs if they align with your soul's needs, the impact of thoughts and emotions on our biology, understanding your life's "purpose," and how plant medicine or psychedelics can aid in expanding consciousness and self-awareness.Episode Resources:https://thrivestatestarter.com/ (free breathwork lessons and longevity & performance resources)https://thrivestatebook.com (Your blueprint for optimal health, longevity and peak performance - 2nd edition)To Connect with Dr. Kien Vuu:https://kienvuu.com/To Connect With Dr. Joy Kong:http://drjoykong.com/Watch Video Episodes on YouTube:https://www.youtube.com/channel/UCZj1GQBWFM5sRAL0iQfcMAQFollow Dr. Joy Kong on Social Media:https://www.instagram.com/dr_joy_kong/https://www.facebook.com/stemcelldrjoyhttps://www.linkedin.com/in/joy-kong-md-4b8627123/For more information about anti-aging regenerative medicine treatment visit:https://uplyftcenter.com *Our content is for informational purposes only and should not be treated as medical or health advice. Please consult with your doctor / healthcare provider if you have any questions about your medical conditions.*

For our latest episode we are talking with Dr. Aviv Regev. Dr. Regev is the head of Genentech Research and Early Development. Prior to Genentech, Regev served as Chair of the Faculty and Core Member at the Broad Institute of MIT and Harvard, and as Professor of Biology at MIT and Investigator at the Howard Hughes Medical Institute. She is a founding co-chair of the Human Cell Atlas.

This is Garrison Hardie with your CrossPolitic Daily News Brief for Tuesday, May 23rd, 2023. Concordis Education Partners: Classical Christian education has reminded us to aim education at truth, but the trivium has been used as a formula rather than a way of training students in discernment. To teach well, you must coach. Concordis Foundation is offering their third annual BOOT CAMP – a faculty summit – July 11-13th in Moscow, Idaho. This is a three-day intensive teaching training where you learn to coach students, using the trivium, so that you can meet students at all learning levels. Learn more at concordispartners.com https://www.westernjournal.com/two-women-told-broken-law-criticizing-male-attempting-breastfeed-child-report/ Two Women Are Told They've Broken the Law by Criticizing Male Attempting to Breastfeed a Child: Report Two Australian women were reportedly given notices informing them that they committed a crime by criticizing a male, who identifies as a woman, that was trying to breastfeed a baby. The news was first reported by the “Pro-Woman, Pro-Child Safeguarding, Anti-Bullsh*t,” media outlet Reduxx. According to the outlet, Twitter contacted the two women — Jasmine Sussex and Leah Whiston — on May 16, notifying them that they had violated Australian law in several of their tweets. The platform told the two that a “government entity or law enforcement agency” had informed them of their alleged crime, and that the platform had been forced to hide the content from Australian users. The posts in question had been critical of Jennifer Buckley, a female-identified male. Buckley had previously announced online that, after two years of transitioning, he had induced lactation and had begun breastfeeding his newborn son, who his wife had given birth to. Sussex was heavily critical of this, telling the U.K.’s Daily Mail that “men shouldn’t breastfeed because breastfeeding [is] for the baby,” and that “there is no evidence that any male-induced milk is equivalent to mother’s milk.” “We have no idea if the substance is even milk. It’s absolutely a human experiment on babies,” she told the outlet. As a volunteer breastfeeding counselor, Sussex was reportedly fired from her job in 2021 for failing to comply with the adoption of “gender neutral” language in breastfeeding care — a claim which the ABA denied to the Daily Mail. A year after, she was removed from the Australian Breastfeeding Association (ABA), Reduxx reported. “I was sacked for. … ‘Engaging in Sectarian Controversy’ in breach of the ABA constitution,” she told Reduxx. “In other words, continuing to talk about the dangers of gender identity ideology for mothers and babies, including how men were forcing their way into the breastfeeding relationship by attempting to induce lactation.” Whiston, meanwhile, is the representative for the Standing for Women Queensland (SFWQ) page. She had posted a Twitter thread on the page, revealing that an LGBT lobby group had allegedly given the ABA $20,000 for them to create an educational booklet about “chest feeding.” https://www.dailysignal.com/2023/05/22/exclusive-leaked-policy-exposes-fox-news-stances-on-woke-ideology/?fbclid=IwAR36KJiUko85jY6nRrQSX4DH2XOZAwUdyaTl-iEhQIfZe9w-ZPnsTY3cAnA Leaked Policy Exposes Fox News Stances on Woke Ideology Fox News employees are allowed to use bathrooms that align with their gender identity, rather than their biological sex, and permitted to dress in alignment with their preferred gender. They must also be addressed by their preferred name and pronouns in the workplace. These are just a few of the policies outlined in the company handbook, dated January 2021, a copy of which was shared with The Daily Signal. Fox also offers to help employees come up with a “Workplace Transition Plan” to ease their gender transition at work. The revelations comes amid conservative consternation at Fox Digital’s use of activist language like “gender affirming care” in stories on its website, as well as the site’s consistent use of female pronouns for biological males like TikTok celebrity Dylan Mulvaney and swimmer Lia Thomas (formerly known as Will Thomas). Fox also drew strong backlash for a June 2022 on-air segment praising a child’s gender transition as an “inspiration to others.” That segment briefly depicted California state Sen. Scott Weiner, a far-left Democrat who led the move to soften sex offender registry requirements for sodomy with minors, and highlighted the activist claim that a child might commit suicide if he or she is not permitted to transition. Carlson’s show was canceled April 24, days after he delivered a viral speech at The Heritage Foundation’s 50th anniversary gala. Fox News Media has not given a reason, simply stating that the two parties “agreed to part ways.” A source who still works at Fox News told The Daily Signal that after Carlson’s show was canceled in April, producers for the new 8 p.m. “Fox News Tonight” program were told not to bash Mulvaney. That directive came from high-level executives, the source said. Fox News did not respond to The Daily Signal’s multiple requests for comment. Under the category “Gender Transition,” Fox’s employee handbook promises that the company is dedicated to “expanding and strengthening” efforts to “sustain a more inclusive work environment.” The Fox employee handbook is posted on Workday, where employees can see company guidelines or policies, a former employee told The Daily Signal. “Employees who are transitioning their gender have the right to be open about their transition if they so choose, and to work in an environment free of harassment, discrimination, or retaliation, and without fear of consequences or transphobia for living openly,” the policy says. Citing the Human Rights Campaign, one of the most prominent LGBTQ organization in the country, the Fox handbook defines a slew of LGBTQ terms, including cisgender, gender expression, gender-fluid, gender identity, gender non-conforming, gender transition, LGBTQ, non-binary, and transgender. For the past several years, Fox received a perfect score on the Human Rights Campaign’s Corporate Equality Index, “the nation’s foremost benchmarking survey and report measuring corporate policies and practices related to LGBTQ+ workplace equality.” A former Fox News employee told The Daily Signal that the company frequently mentions this perfect score in employee training materials. “Fox News devotes hours of programming to attacking ‘woke companies,’ but ironically Fox is as woke as the rest of them,” another former Fox News employee told The Daily Signal, emphasizing that Fox viewers would be “astonished to find out what the company is like.” Fox’s policies appear to be aligned with the legal requirements in New York City, where the company is headquartered, as well as California, where a large number of its employees work. The handbook explicitly states that any employee “may access the restroom corresponding to their gender identity.” “If a transitioning employee expresses a desire for increased privacy they will be provided access to a single occupancy restroom where available,” the handbook says. “However, no employee shall be required to use a single occupancy restroom if they do not wish to do so.” When trans-identifying TikTok star Mulvaney was first gaining prominence last year, producers for “Tucker Carlson Tonight” had to fight to be able to refer to Mulvaney with male pronouns in the show’s chyrons, the former “Tucker Carlson Tonight” producer told The Daily Signal. Carlson’s team also fought to be able to host The Daily Wire’s Matt Walsh on trans issues, the producer said, but the team was repeatedly met with resistance from Fox on this due to Walsh’s frank condemnation of transgender ideology. This may have also been due in part to Fox’s view of The Daily Wire as a competitor, the former producer suggested. https://www.based-politics.com/2023/05/22/this-public-college-is-giving-out-paid-internships-that-openly-exclude-white-people/ This public college is giving out paid internships that openly exclude white people Martin Luther King Jr. famously dreamed of a day when Americans would be judged not by the color of their skin but by the content of their character. Well, keep dreaming, MLK, because segregation and open race discrimination are making a comeback—this time, in progressive bastions like our higher education system and in the name of “Diversity, Equity, and Inclusion.” The University of Minnesota just got hit with a federal civil rights complaint because it’s openly conditioning a paid internship program on the basis of race. Their “Multicultural Summer Research Opportunities Program” is “an intensive 10 week summer program in which undergraduate students of color work full-time with a faculty mentor on a research project.” It aims to help in “preparing students for graduate school and developing research skills,” and pays students a $6,000 stipend. A condition of the program is that it is only open to students who “identify” as “a student of color or Native American.” This program’s legality is being challenged by the Legal Insurrection Foundation’s Equal Protection Project (EPP), which “seeks to ensure equal protection under the law and non-discrimination by the government” and “opposes racial discrimination in any form.” They just filed a complaint with the Office of Civil Rights of the U.S. Department of Education arguing that this internship program violates the Civil Rights Act and the Equal Protection clause of the Constitution. “The U. Minnesota segregated summer program is inexcusable, and it’s shocking that a major university would so openly make educational opportunities open only to students of a certain skin color,” EPP President Bill told Fox News Digital. “There is no good form of racial discrimination. Depriving white students of educational opportunities does not promote racial or any other form of justice.” https://www.breitbart.com/politics/2023/05/21/census-new-york-city-loses-nearly-half-a-million-residents-in-two-years/ New York City Loses Nearly Half a Million Residents in Two Years New York City has lost nearly half a million residents over the course of just two years, newly released United States Census Bureau data reveals. The Census Bureau data, which shows population estimates for mid-2022, finds that fewer than 8.4 million residents remain living in New York City — still making the Big Apple the nation’s most populous city by several million. In April 2020, the very start of the Chinese coronavirus pandemic, more than 8.8 million residents lived in New York City. This figure indicates a population loss of more than five percent from April 2020 to July 2022 with almost half a million residents leaving the city. Americans moving out of deep blue cities is widespread, the Census Bureau data shows. The second largest city, Los Angeles, California, and the third largest city, Chicago, Illinois, also lost residents over the course of two years. In Los Angeles, for instance, about 3.8 million residents remain in the city as of July 2022 compared to about 3.9 million residents in April 2020, a loss of about 100,000 residents. Similarly, Chicago had about 2.67 million residents as of July 2022 but in April 2020, the city had about three percent more residents. Over the two years, about 85,000 residents left Chicago. And now for the rundown… https://andmagazine.substack.com/p/china-is-building-killer-robots-using Many of us have seen The Terminator, a 1984 film starring Arnold Schwarzenegger. It depicts an almost unstoppable robot sent back in time from 2029 to 1984. Its mission was to kill a woman whose unborn son will save humanity from Skynet, a 2029 artificial intelligence system that had become self-aware and then decided to destroy all of mankind because humans were interfering in their plans and programs. The Chinese Communist Party, the CCP, is now creating their version of the Terminator -- an army of battlefield killer robots that will not be managed by humans in any way and, instead, will be controlled by an artificial intelligence (AI) system. The Chinese plan for building such lethal autonomous robots was revealed by Zeng Yi, an executive in a Chinese government-owned company named Norinco. He said, “In future battlegrounds, there will be no people fighting,” adding that autonomous AI platforms are “inevitable.” https://www.washingtonexaminer.com/news/washington-secrets/explosion-of-ap-climate-change-stories-following-8m-enviro-grant In the year following a grant of more than $8 million to the Associated Press from key climate change advocates, the news service has poured out at least 64 stories warning of environmental calamity, according to a new media study.Media Research Center Business charted the stories and language used following the multimillion-dollar grant and found that AP also used over 500 environmental extremism buzzwords in the stories. The media giant, which feeds news outlets worldwide, received grants totaling $8 million from the William and Flora Hewlett Foundation, the Howard Hughes Medical Institute, Quadrivium, the Rockefeller Foundation, and the Walton Family Foundation in February 2022. AP said it would hire 20 new environmental writers with the money to create a climate swat team to “enhance the global understanding of climate change and its impact across the world.” https://www.outkick.com/trans-high-school-track-runner-robs-female-athlete-of-state-championship-bid/ Another day, another biological male taking opportunities from deserving females.Athena Ryan took second place Saturday in the high school women’s 1600 meter race at the North Coast Meet of Champions in California. The top three athletes advance to the CIF State Track & Field Championships next week. So the fourth-place finisher, Adeline Johnson, missed her chance to compete in State by just one spot. A spot taken by a boy. Ryan, a junior at Sonoma Academy, competed on the men’s team in 2021. But he’s been running in women’s events for the past two seasons. In Saturday’s meet, he clocked a season-record 4:55:91 in the 1600m finals. He would have finished last in the male category. The slowest male time in the preliminaries was 4:46:54. The slowest male time in the finals was 4:35:12. A group of advocates held a banner at the event that simply read, “Protect Female Sports.” They were eventually asked to leave and then escorted off the premises. But not before they had an interesting exchange with an angry passerby. How about we end with some cool news… https://www.dailyfetched.com/soldier-who-lost-both-legs-in-afghanistan-does-the-unimaginable-and-climbs-everest-anything-is-possible/ British army soldier Gurkha veteran Hari Budha Magar, who lost both his legs while serving in Afghanistan, has successfully climbed to the top of the world’s tallest mountain, Mount Everest. Magar, a father of three, served as a corporal in the Gurkha regiment in the British Army. After Magar lost his legs to an improvised explosive device in 2010, he thought his life was “completely finished.” The veteran, who now lives in Canterbury, England, battled depression and alcoholism following the explosion. But Magar persevered. The veteran helped strike down a ban on both double amputees and blind people climbing Everest, ensuring he would have a chance at overcoming both nature and his injuries. According to the BBC, Magar hoped to “inspire others” and “change perceptions on disability” and set off with a team of Nepalese climbers to combat Everest. He” set off on May 6 with a team of Nepalese climbers led by Krish Thapa, a fellow Gurkha veteran and British special forces mountain troop leader. Magar announced he “stood victorious” atop Everest around 3 p.m. on May 19, noting, “Disability is no barrier to reaching the 8,849-metre peak.”

This is Garrison Hardie with your CrossPolitic Daily News Brief for Tuesday, May 23rd, 2023. Concordis Education Partners: Classical Christian education has reminded us to aim education at truth, but the trivium has been used as a formula rather than a way of training students in discernment. To teach well, you must coach. Concordis Foundation is offering their third annual BOOT CAMP – a faculty summit – July 11-13th in Moscow, Idaho. This is a three-day intensive teaching training where you learn to coach students, using the trivium, so that you can meet students at all learning levels. Learn more at concordispartners.com https://www.westernjournal.com/two-women-told-broken-law-criticizing-male-attempting-breastfeed-child-report/ Two Women Are Told They've Broken the Law by Criticizing Male Attempting to Breastfeed a Child: Report Two Australian women were reportedly given notices informing them that they committed a crime by criticizing a male, who identifies as a woman, that was trying to breastfeed a baby. The news was first reported by the “Pro-Woman, Pro-Child Safeguarding, Anti-Bullsh*t,” media outlet Reduxx. According to the outlet, Twitter contacted the two women — Jasmine Sussex and Leah Whiston — on May 16, notifying them that they had violated Australian law in several of their tweets. The platform told the two that a “government entity or law enforcement agency” had informed them of their alleged crime, and that the platform had been forced to hide the content from Australian users. The posts in question had been critical of Jennifer Buckley, a female-identified male. Buckley had previously announced online that, after two years of transitioning, he had induced lactation and had begun breastfeeding his newborn son, who his wife had given birth to. Sussex was heavily critical of this, telling the U.K.’s Daily Mail that “men shouldn’t breastfeed because breastfeeding [is] for the baby,” and that “there is no evidence that any male-induced milk is equivalent to mother’s milk.” “We have no idea if the substance is even milk. It’s absolutely a human experiment on babies,” she told the outlet. As a volunteer breastfeeding counselor, Sussex was reportedly fired from her job in 2021 for failing to comply with the adoption of “gender neutral” language in breastfeeding care — a claim which the ABA denied to the Daily Mail. A year after, she was removed from the Australian Breastfeeding Association (ABA), Reduxx reported. “I was sacked for. … ‘Engaging in Sectarian Controversy’ in breach of the ABA constitution,” she told Reduxx. “In other words, continuing to talk about the dangers of gender identity ideology for mothers and babies, including how men were forcing their way into the breastfeeding relationship by attempting to induce lactation.” Whiston, meanwhile, is the representative for the Standing for Women Queensland (SFWQ) page. She had posted a Twitter thread on the page, revealing that an LGBT lobby group had allegedly given the ABA $20,000 for them to create an educational booklet about “chest feeding.” https://www.dailysignal.com/2023/05/22/exclusive-leaked-policy-exposes-fox-news-stances-on-woke-ideology/?fbclid=IwAR36KJiUko85jY6nRrQSX4DH2XOZAwUdyaTl-iEhQIfZe9w-ZPnsTY3cAnA Leaked Policy Exposes Fox News Stances on Woke Ideology Fox News employees are allowed to use bathrooms that align with their gender identity, rather than their biological sex, and permitted to dress in alignment with their preferred gender. They must also be addressed by their preferred name and pronouns in the workplace. These are just a few of the policies outlined in the company handbook, dated January 2021, a copy of which was shared with The Daily Signal. Fox also offers to help employees come up with a “Workplace Transition Plan” to ease their gender transition at work. The revelations comes amid conservative consternation at Fox Digital’s use of activist language like “gender affirming care” in stories on its website, as well as the site’s consistent use of female pronouns for biological males like TikTok celebrity Dylan Mulvaney and swimmer Lia Thomas (formerly known as Will Thomas). Fox also drew strong backlash for a June 2022 on-air segment praising a child’s gender transition as an “inspiration to others.” That segment briefly depicted California state Sen. Scott Weiner, a far-left Democrat who led the move to soften sex offender registry requirements for sodomy with minors, and highlighted the activist claim that a child might commit suicide if he or she is not permitted to transition. Carlson’s show was canceled April 24, days after he delivered a viral speech at The Heritage Foundation’s 50th anniversary gala. Fox News Media has not given a reason, simply stating that the two parties “agreed to part ways.” A source who still works at Fox News told The Daily Signal that after Carlson’s show was canceled in April, producers for the new 8 p.m. “Fox News Tonight” program were told not to bash Mulvaney. That directive came from high-level executives, the source said. Fox News did not respond to The Daily Signal’s multiple requests for comment. Under the category “Gender Transition,” Fox’s employee handbook promises that the company is dedicated to “expanding and strengthening” efforts to “sustain a more inclusive work environment.” The Fox employee handbook is posted on Workday, where employees can see company guidelines or policies, a former employee told The Daily Signal. “Employees who are transitioning their gender have the right to be open about their transition if they so choose, and to work in an environment free of harassment, discrimination, or retaliation, and without fear of consequences or transphobia for living openly,” the policy says. Citing the Human Rights Campaign, one of the most prominent LGBTQ organization in the country, the Fox handbook defines a slew of LGBTQ terms, including cisgender, gender expression, gender-fluid, gender identity, gender non-conforming, gender transition, LGBTQ, non-binary, and transgender. For the past several years, Fox received a perfect score on the Human Rights Campaign’s Corporate Equality Index, “the nation’s foremost benchmarking survey and report measuring corporate policies and practices related to LGBTQ+ workplace equality.” A former Fox News employee told The Daily Signal that the company frequently mentions this perfect score in employee training materials. “Fox News devotes hours of programming to attacking ‘woke companies,’ but ironically Fox is as woke as the rest of them,” another former Fox News employee told The Daily Signal, emphasizing that Fox viewers would be “astonished to find out what the company is like.” Fox’s policies appear to be aligned with the legal requirements in New York City, where the company is headquartered, as well as California, where a large number of its employees work. The handbook explicitly states that any employee “may access the restroom corresponding to their gender identity.” “If a transitioning employee expresses a desire for increased privacy they will be provided access to a single occupancy restroom where available,” the handbook says. “However, no employee shall be required to use a single occupancy restroom if they do not wish to do so.” When trans-identifying TikTok star Mulvaney was first gaining prominence last year, producers for “Tucker Carlson Tonight” had to fight to be able to refer to Mulvaney with male pronouns in the show’s chyrons, the former “Tucker Carlson Tonight” producer told The Daily Signal. Carlson’s team also fought to be able to host The Daily Wire’s Matt Walsh on trans issues, the producer said, but the team was repeatedly met with resistance from Fox on this due to Walsh’s frank condemnation of transgender ideology. This may have also been due in part to Fox’s view of The Daily Wire as a competitor, the former producer suggested. https://www.based-politics.com/2023/05/22/this-public-college-is-giving-out-paid-internships-that-openly-exclude-white-people/ This public college is giving out paid internships that openly exclude white people Martin Luther King Jr. famously dreamed of a day when Americans would be judged not by the color of their skin but by the content of their character. Well, keep dreaming, MLK, because segregation and open race discrimination are making a comeback—this time, in progressive bastions like our higher education system and in the name of “Diversity, Equity, and Inclusion.” The University of Minnesota just got hit with a federal civil rights complaint because it’s openly conditioning a paid internship program on the basis of race. Their “Multicultural Summer Research Opportunities Program” is “an intensive 10 week summer program in which undergraduate students of color work full-time with a faculty mentor on a research project.” It aims to help in “preparing students for graduate school and developing research skills,” and pays students a $6,000 stipend. A condition of the program is that it is only open to students who “identify” as “a student of color or Native American.” This program’s legality is being challenged by the Legal Insurrection Foundation’s Equal Protection Project (EPP), which “seeks to ensure equal protection under the law and non-discrimination by the government” and “opposes racial discrimination in any form.” They just filed a complaint with the Office of Civil Rights of the U.S. Department of Education arguing that this internship program violates the Civil Rights Act and the Equal Protection clause of the Constitution. “The U. Minnesota segregated summer program is inexcusable, and it’s shocking that a major university would so openly make educational opportunities open only to students of a certain skin color,” EPP President Bill told Fox News Digital. “There is no good form of racial discrimination. Depriving white students of educational opportunities does not promote racial or any other form of justice.” https://www.breitbart.com/politics/2023/05/21/census-new-york-city-loses-nearly-half-a-million-residents-in-two-years/ New York City Loses Nearly Half a Million Residents in Two Years New York City has lost nearly half a million residents over the course of just two years, newly released United States Census Bureau data reveals. The Census Bureau data, which shows population estimates for mid-2022, finds that fewer than 8.4 million residents remain living in New York City — still making the Big Apple the nation’s most populous city by several million. In April 2020, the very start of the Chinese coronavirus pandemic, more than 8.8 million residents lived in New York City. This figure indicates a population loss of more than five percent from April 2020 to July 2022 with almost half a million residents leaving the city. Americans moving out of deep blue cities is widespread, the Census Bureau data shows. The second largest city, Los Angeles, California, and the third largest city, Chicago, Illinois, also lost residents over the course of two years. In Los Angeles, for instance, about 3.8 million residents remain in the city as of July 2022 compared to about 3.9 million residents in April 2020, a loss of about 100,000 residents. Similarly, Chicago had about 2.67 million residents as of July 2022 but in April 2020, the city had about three percent more residents. Over the two years, about 85,000 residents left Chicago. And now for the rundown… https://andmagazine.substack.com/p/china-is-building-killer-robots-using Many of us have seen The Terminator, a 1984 film starring Arnold Schwarzenegger. It depicts an almost unstoppable robot sent back in time from 2029 to 1984. Its mission was to kill a woman whose unborn son will save humanity from Skynet, a 2029 artificial intelligence system that had become self-aware and then decided to destroy all of mankind because humans were interfering in their plans and programs. The Chinese Communist Party, the CCP, is now creating their version of the Terminator -- an army of battlefield killer robots that will not be managed by humans in any way and, instead, will be controlled by an artificial intelligence (AI) system. The Chinese plan for building such lethal autonomous robots was revealed by Zeng Yi, an executive in a Chinese government-owned company named Norinco. He said, “In future battlegrounds, there will be no people fighting,” adding that autonomous AI platforms are “inevitable.” https://www.washingtonexaminer.com/news/washington-secrets/explosion-of-ap-climate-change-stories-following-8m-enviro-grant In the year following a grant of more than $8 million to the Associated Press from key climate change advocates, the news service has poured out at least 64 stories warning of environmental calamity, according to a new media study.Media Research Center Business charted the stories and language used following the multimillion-dollar grant and found that AP also used over 500 environmental extremism buzzwords in the stories. The media giant, which feeds news outlets worldwide, received grants totaling $8 million from the William and Flora Hewlett Foundation, the Howard Hughes Medical Institute, Quadrivium, the Rockefeller Foundation, and the Walton Family Foundation in February 2022. AP said it would hire 20 new environmental writers with the money to create a climate swat team to “enhance the global understanding of climate change and its impact across the world.” https://www.outkick.com/trans-high-school-track-runner-robs-female-athlete-of-state-championship-bid/ Another day, another biological male taking opportunities from deserving females.Athena Ryan took second place Saturday in the high school women’s 1600 meter race at the North Coast Meet of Champions in California. The top three athletes advance to the CIF State Track & Field Championships next week. So the fourth-place finisher, Adeline Johnson, missed her chance to compete in State by just one spot. A spot taken by a boy. Ryan, a junior at Sonoma Academy, competed on the men’s team in 2021. But he’s been running in women’s events for the past two seasons. In Saturday’s meet, he clocked a season-record 4:55:91 in the 1600m finals. He would have finished last in the male category. The slowest male time in the preliminaries was 4:46:54. The slowest male time in the finals was 4:35:12. A group of advocates held a banner at the event that simply read, “Protect Female Sports.” They were eventually asked to leave and then escorted off the premises. But not before they had an interesting exchange with an angry passerby. How about we end with some cool news… https://www.dailyfetched.com/soldier-who-lost-both-legs-in-afghanistan-does-the-unimaginable-and-climbs-everest-anything-is-possible/ British army soldier Gurkha veteran Hari Budha Magar, who lost both his legs while serving in Afghanistan, has successfully climbed to the top of the world’s tallest mountain, Mount Everest. Magar, a father of three, served as a corporal in the Gurkha regiment in the British Army. After Magar lost his legs to an improvised explosive device in 2010, he thought his life was “completely finished.” The veteran, who now lives in Canterbury, England, battled depression and alcoholism following the explosion. But Magar persevered. The veteran helped strike down a ban on both double amputees and blind people climbing Everest, ensuring he would have a chance at overcoming both nature and his injuries. According to the BBC, Magar hoped to “inspire others” and “change perceptions on disability” and set off with a team of Nepalese climbers to combat Everest. He” set off on May 6 with a team of Nepalese climbers led by Krish Thapa, a fellow Gurkha veteran and British special forces mountain troop leader. Magar announced he “stood victorious” atop Everest around 3 p.m. on May 19, noting, “Disability is no barrier to reaching the 8,849-metre peak.”

Dr. Kevan M. Shokat is Professor in the Department of Cellular and Molecular Pharmacology at the University of California San Francisco, Professor in the Department of Chemistry at the University of California Berkeley, and an Investigator with the Howard Hughes Medical Institute. Kevan's lab uses approaches from chemistry to address unsolved challenges and opportunities for discovery in biology and medicine. His goal is to apply chemistry to biology in the most impactful, interesting, and meaningful ways while pursuing his curiosity. The lab has been investigating key signaling proteins in diseases such as cancer to develop new treatments. When he's not working, Kevan enjoys spending time with family, cycling with his friends, getting exercise, being out in nature, and reading biographies of scientists. Kevan received his B.A in chemistry from Reed College and his Ph.D. in organic chemistry from the University of California, Berkeley. Afterwards, he received a Life Sciences Research Foundation Fellowship to conduct postdoctoral research at Stanford University, and he served on the faculty at Princeton University before joining the faculty at his current institutions. Kevan has received numerous awards and honors over the course of his career, including the 2023 Sjöberg Prize from the The Royal Swedish Academy of Sciences, the 2023 National Academy of Sciences Award for Scientific Discovery, the 2023 Howard Vollum Award for Distinguished Accomplishment in Science and Technology from his alma mater Reed College, the 2022 American Association for Cancer Research's Award for Outstanding Achievement in Chemistry in Cancer Research, and many others. He was also named a Pew Scholar in the Biomedical Sciences, a Searle Scholar, a Cottrell Scholar, a Glaxo-Wellcome Scholar in Organic Chemistry, and an Alfred P. Sloan Research Fellow. In addition, Kevan is an elected Member of the National Academy of Sciences, a Member of the National Academy of Medicine, and a Fellow of the American Academy of Arts and Sciences. In our interview, he shares more about his life and science.

It all started with the Big Bang. We all know that. But what does that even mean? And how did the big bang lead to us?! Our body is made up of “starstuff”, and by by understanding how everything started, we can make better choices on living. Dan Levitt spent over twenty-five years writing, producing, and directing award-winning documentaries for National Geographic, Discovery, Science, History, PBS, and the Howard Hughes Medical Institute. He began his career as a Peace Corps volunteer in Kenya, teaching high school physics and biology. Dan's book, What's Gotten Into You: The Story of Your Body's Atoms, from the Big Bang Through Last Night's Dinner, is available now. Find out more about Dan at danlevitt.com. Support the Show - Become a Patron! Help us grow and become a Patron today: https://www.patreon.com/smartpeoplepodcast Sponsors: Huel – Go to huel.com/smart and get a free t-shirt and shaker with your first order. Notion - Try Notion AI for free when you go to notion.com/smart. Wonolo – Head over to wonolo.com/smart and learn how Wonolo makes finding hard workers easy. Learn more about your ad choices. Visit megaphone.fm/adchoices