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With recent challenges in online advertising, it's crucial to explore alternative avenues for customer acquisition. Learn how building products and marketing strategies based on your ICP can fuel quick success and scalability for your business.In today's episode, Jordan West and Michael Epstein, Co-Founder of PostPilot, discussed the challenges of Q4 and how to go beyond abandoned checkout communication and acquire customers through targeted direct mail campaigns. Listen and learn in this episode!Key takeaways from this episode:Leveraging first-party data and creating lookalike models based on best customers can help identify and target high-potential prospects.Retention campaigns are key for maximizing customer value, despite privacy updates limiting certain retargeting methods.Reactivating dormant customers can lead to significant returns on ad spend, even for customers who haven't made a purchase in years.Exploring alternative customer acquisition avenues outside of traditional online advertising platforms is important for long-term sustainability.Discount offers in direct mail campaigns should match or exceed those in email campaigns to incentivize customers on the verge of defecting.Targeting specific customer segments, such as expectant mothers or new parents, can yield successful results.Building lookalike audiences for cold acquisition, similar to Facebook's approach, can help identify new prospects with high potential.Recommended Podcast/Audiobook:Prof G: https://podcasts.voxmedia.com/show/the-prof-g-pod-with-scott-gallowayElon Musk Biography: https://www.amazon.com/Elon-Musk-Walter-Isaacson/dp/1982181281Recommended App/Tool:Sendlane: https://www.sendlane.com/Klaviyo: https://www.klaviyo.com/Shopify: https://www.shopify.com/Retention.com: https://retention.com/Hubspot: https://www.hubspot.com/Salvit Advisors: https://www.salvit.com/Salvit Advisors Leverage Playbook: https://bit.ly/3RFKaw6Why the 'Leverage Playbook'?Data-Driven Decisions: By connecting your analytics ecosystem—be it GA, Shopify, or Amazon—Salvit Advisors will identify 2-3 immediate wins that have been lurking right under your nose.Customized Strategy: Receive a pitch deck tailored specifically for your brand, combining your unique data.Immediate Impact: These insights aren't just theoretical. They're actionable recommendations that can drive tangible profit for your business.Get 5 Offers for 2 Products (10 in total) along with 10 highly engaging tried and true creatives, 30 captivating headlines, descriptions, and ad texts sent to you for only $99. Go to https://www.upgrowthcommerce.com/offer and order now - this offer is only available for a limited time.We love our podcast community and listeners so much that we have decided to offer a free eCommerce Growth Plan for your brand! To learn more and how we can help, click here: upgrowthcommerce.com/grow Join our community and connect with other eCommerce brand owners and marketers! https://www.facebook.com/groups/secretstoscalingpodcast
A network promoting disinformation to Irish TikTok users with the aim of “intensifying social conflict” has been discovered and removed by the social media giant. The information was disclosed in data reported by TikTok to the European Commission under a new code of conduct that requires major tech platforms to report disinformation on their networks and detail their efforts to combat it. The network originated in Ireland but little else has been revealed by the company. Irish Times Europe Correspondent Naomi O'Leary explains to In the News how disinformation is spreading on social media, how users are resistant to fact checking measures and what it means. Presented by Bernice Harrison. Produced by Suzanne Brennan Hosted on Acast. See acast.com/privacy for more information.
On today's episode of The American Land Man Podcast, we are back in the studio talking with Alec Marquette. We get into the importance of mindset and strategy, the concept of house hacking and using direct mail to find deals. We Discuss: He has grossed $438,000 in sales with a $138,000 gross income, doing this business as a side hustle House hacking allows Alec to live in a duplex while collecting rent from his sister-in-law as a tenant Alec follows an arbitrage model, finding sellers who undervalue their land and reselling it at market value Alec values stability and prefers to keep the rent below market rate to ensure a hassle-free living situation Targeting specific areas within a certain radius of a metro area can increase your chances of finding motivated sellers Analyzing flood zones, property access, nearby amenities, and tax information Setting up a landing page can help attract buyers and generate passive income He leverages his unique work schedule as a firefighter to devote time to his land investing business Targeting markets with high demand for land increases the chances of successful sales Targeting specific areas and property sizes can help narrow down potential buyers Motivation is the key when seeking land deals Understand the impact of subdivision potential on land prices Finding motivated sellers is essential for securing properties at a favorable price And So Much More! Connect: -https://bit.ly/NeilHaugerWhitetailProperties -https://bit.ly/NeilHaugerFacebook -https://bit.ly/NeilHaugerYouTube -https://bit.ly/NeilHaugerInstagram --- Support this podcast: https://podcasters.spotify.com/pod/show/neil-hauger/support
Patron of the podcast, Mathew, sent this question in. Are there accounts of artillery specifically targeting leaders, for example, a Legatus or centurion? Or dedicated expert archers, etc., to do the same? Imagine a sniper-type scenario. This seems like a tactic that could have been used to demoralise a force and eliminate command and control quickly. Join us on Patron patreon.com/ancientwarfarepodcast
Two teenagers now face murder charges in Las Vegas for a horrifying act of violence targeting a bicyclist. The authorities disclosed this shocking incident during a press conference on Tuesday, shedding light on a series of tragic events that transpired on the morning of August 14. Las Vegas police have linked the two teenagers to a string of at least three hit-and-run incidents on that morning, ultimately culminating in the tragic death of 64-year-old Andreas Rene Probst. Probst, a former police chief from Bell, California, met his untimely demise in what can only be described as a disturbing and callous act. The chilling incident was captured on video recorded from the front passenger seat of the teenagers' vehicle. The footage unfolds with Probst cycling along the side of a nearly deserted road near the curb. As those inside the vehicle laugh, the car approaches Probst from behind, then swerves violently toward him, striking his bicycle head-on. The impact sends Probst hurtling onto the car's hood and crashing through the windshield. The last frame of the video shows Probst lying motionless on the ground beside the curb. Deputy Police Chief Nick Farese did not mince words when he addressed the disturbing video, labeling it as appalling and characterizing the act as "cowardly." Clark County District Attorney Steve Wolfson has taken a personal interest in the case and has declared his intent to charge both teenagers as adults. However, he refrained from disclosing their identities at this time, stating that justice will be served in due course. At the Tuesday press conference, Taylor Probst, the victim's daughter, delivered a tearful tribute to her father, known affectionately as Andy. She described him as a man of honor and integrity who dedicated over 35 years to a career in law enforcement. In her emotional address, she expressed the profound devastation her family feels over the senseless murder of her father, emphasizing that "Andy's life was robbed by two individuals who did not believe that lives of others matter." The investigation took a significant turn when the 17-year-old driver was arrested on the day of the crashes, initially facing traffic-related charges related to the fatal hit-and-run incidents. However, it wasn't until several weeks later that a school resource officer provided investigators with the video evidence, leading to the elevation of charges to murder for the driver. This discovery also triggered a police search for the passenger who was present in the video. The second teenager was apprehended on Tuesday. According to the police, the horrifying spree of vehicular crimes began just before dawn when the teenagers struck a 72-year-old bicyclist before fleeing the scene and subsequently crashing into a Toyota Corolla. Remarkably, the driver of the Toyota emerged from the collision without injuries, as reported by the police. The extent of the injuries sustained by the initial bicyclist was not detailed. Shortly after colliding with the Toyota, the teenagers targeted Andreas Rene Probst as he was riding his bicycle in a designated bike lane. They fled the scene, leaving Probst gravely injured and stranded by the side of the road, their laughter echoing in the background, as recounted by Deputy Police Chief Farese. Want to listen to ALL of our podcasts AD-FREE? Subscribe through APPLE PODCASTS, and try it for three days free: https://tinyurl.com/ycw626tj Follow Our Other Cases: https://www.truecrimetodaypod.com The latest on Catching the Long Island Serial Killer, Awaiting Admission: BTK's Unconfessed Crimes, Chad & Lori Daybell, The Murder of Ana Walshe, Alex Murdaugh, Bryan Kohberger, Lucy Letby, Kouri Richins, Justice for Harmony Montgomery, The Murder of Stephen Smith, The Murder of Madeline Kingsbury, and much more! Listen at https://www.truecrimetodaypod.com
Day 580.Today, we discuss how the IOC has banned Russian athletes from the Asian Games, and look at the latest threats to undersea cables. Contributors:Dominic Nicholls (Host, Associate Editor, Defence). @DomNicholls on Twitter.Gareth Corfield (Senior Tech Reporter). @GazTheJourno on Twitter.Kateryna Stepanenko (Russia Deputy Team Lead, ISW). @KatStepanenko on Twitter. Find out more: Subscribe to The Telegraph: telegraph.co.uk/ukrainethelatestEmail: ukrainepod@telegraph.co.ukSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Naomi O'Leary, Europe Correspondent for the Irish Times, reports on a covert influence operation, involving inauthentic accounts, that post divisive content with the aim to intensify social conflict.
Ciaran O'Connor senior analyst with the Institute for Strategic Dialogue joins us
Featuring an interview with Dr Paul G Richardson, including the following topics: Biologic rationale for targeting protein degradation pathways as a therapeutic approach in multiple myeloma (MM); mechanism of action of CELMoDs (0:00) Similarities and differences between iberdomide, mezigdomide and standard immunomodulatory drugs (7:14) Compassionate use of melflufen and belantamab mafodotin (12:08) Current management strategies for newly diagnosed MM (16:30) DETERMINATION: Evaluation of trial findings on racial and ethnic disparities and differential outcomes (23:02) Tailoring of up-front daratumumab-based therapies; management of extramedullary disease (33:17) CME information and select publications
Featuring a slide presentation and related discussion from Dr Paul G Richardson, including the following topics: Biologic rationale for targeting protein degradation pathways as a therapeutic approach in multiple myeloma (MM); mechanism of action of CELMoDs (0:00) Published efficacy and safety findings with iberdomide-containing combination regimens from the Phase I/II CC-220-MM-001 study (6:30) Emerging data with mezigdomide/dexamethasone for relapsed/refractory MM (13:22) Early results with and ongoing investigations of mezigdomide/dexamethasone in combination with a proteasome inhibitor (29:54) CME information and select publications
In this episode of Being in the Arena, host Zach Arend addresses the concept of 'reluctant leadership.' Targeting entrepreneurs and business owners who are hesitant about their ability to lead, Zach delves into the reasons behind this reluctance and offers actionable advice for stepping into one's authentic power as a leader. He argues that reluctance to lead is actually a good thing, as it often means you care deeply about your team and business. He highlights the importance of shifting from task delegation to outcome delegation and urges listeners to invest in the 'who'—the right people—to make leadership less draining and more empowering. The episode is a practical guide for those looking to overcome their hesitations and embrace their roles as impactful leaders.
Dr Paul G Richardson from Dana-Farber Cancer Institute in Boston discusses the emerging role of CELMoDs and other novel approaches to targeting protein degradation pathways in the treatment of multiple myeloma, moderated by Dr Neil Love. Produced by Research To Practice. CME information and select publications here (https://www.researchtopractice.com/OncologyTodayCELMoDsMM23)
In 2001, Chris Carr launched a start-up in his spare time – a marketing company called Farotech. What started primarily as a web design firm quickly grew into a comprehensive digital marketing agency specializing in helping clients in the healthcare, orthopedics, manufacturing, SaaS, and cybersecurity fields see explosive growth through a proven marketing system. Since early 2020, Chris has become a thought leader in artificial intelligence (AI). Through years of analysis, workshops, and hands-on experience, he's observed the rise of modern AI and its potential to reshape the business landscape. Recognizing that most businesses are not ready for this massive disruption from AI, Chris offers workshops and lunch-and-learns to equip businesses for the future that's already here. Find out more at farotech.com. Today, we're going to talk about AI and branding. My guest, Chris Carr, is at the forefront of these topics. He will share actionable tips that you can start doing now to incorporate AI into your business so you aren't left behind when everyone else moves forward with that technology. “If you're an individual who's not willing to adopt that technology [AI], there's a chance you will get replaced by somebody who does. ” – Chris CarrThis week on SmallBizChat Podcast:Building hyper-personalization into your marketing. Why your marketing should start with your branding. The stages of solving a problem. How AI is changing every industry. Targeting your brand to your audience. Standing out in an AI-filled marketplace.Chat priming. Authenticity in branding. Resources Mentioned:Become Your Own Boss: https://smallbizladyuniversity.com/ Boss Quiz: https://smallbizladyuniversity.com/boss-quiz/ There's an AI for That: https://theresanaiforthat.com/ SparkToro: https://sparktoro.com/ BuzzSumo: https://buzzsumo.com/ Connect with Chris Carr:Website: https://farotech.com/ LinkedIn: https://www.linkedin.com/in/chris-carr-84b1a02/ Twitter: https://twitter.com/chris_carr YouTube: https://www.youtube.com/@Farotech Podcast: https://farotech.com/podcasts/ LinkedIn:Can your brand survive and thrive in an AI-centric world? Chris Carr of Farotech believes it can, but only with the right strategies in place. Join us on the SmallBizChat Podcast as we explore the role of AI in branding and the key shifts businesses must make to remain relevant. Listen in today!#SmallBizChat #business #AI #branding
This episode reports on phishing campaigns against the hospitality sector, a new ransomware operator and more
Nicholas Goldner, PhD, is the CEO and co-founder of resistanceBio, where he leads a mission to outsmart cancer by developing innovative therapies targeting treatment resistance mechanisms. He also serves as a venture partner at Pioneer Fund, actively investing in and supporting early-stage founders solving complex problems with science and technology. With a distinguished academic background, including a PhD in Molecular Cell Biology from Washington University in St. Louis, Nicholas combines scientific expertise with entrepreneurial prowess to create impactful solutions for pressing health challenges. Newsletter sign up (new and exciting developments) https://learningwithlowell.us12.list-manage.com/subscribe?u=08ed8a56013d8b3a3c01e27fc&id=6ecaa9189b Join this channel to get access to perks: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-Q/join Over 321 books from 170 plus interviews over 5 years https://www.learningwithlowell.com/over-321-books-from-170-interviews-over-5-years-for-autodidacts/ https://youtu.be/h-xQBKlgAoQ PODCAST INFO: The Learning With Lowell show is a series for the everyday mammal. In this show we'll learn about leadership, science, and people building their change into the world. The goal is to dig deeply into people who most of us wouldn't normally ever get to hear. The Host of the show – Lowell Thompson- is a lifelong autodidact, serial problem solver, and founder of startups. LINKS Spotify: https://open.spotify.com/show/66eFLHQclKe5p3bMXsCTRH RSS: https://www.learningwithlowell.com/feed/podcast/ Youtube: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-Q Youtube clips: https://www.youtube.com/channel/UC-B5x371AzTGgK-_q3U_KfA Website: https://www.learningwithlowell.com/ Nicholas Goldner links https://www.linkedin.com/in/nicholas-goldner/ https://www.resistance.bio/ Timestamps 00:00 Introducing Nicholas Goldner and ResistanceBIO 00:30 Saving 600,000 people a year 01:30 ENCER models for pharma 04:30 Importance of ResistanceBIO to understanding cancer 05:40 Why cancer comes back / resistance mechanisms 07:30 Cure vs treatment 09:00 Cancer is natural 10:30 Full ResistanceBIO platform explained 14:55 Last 3 years of development 17:30 Knowing they were on the right path, supportive data, and deeper understanding 24:50 Business incentive and business model explained 28:30 Hiding cure for cancer myth 31:00 Diagnostic potential 32:30 Last things pharma is looking for from them 34:30 Confidence in targeting/ therapy 35:45 Platform helping understand why failures happen 38:00 Adding 10,000,000,000 years of life 40:20 Nerding out and coffee 41:20 Headache caffeine 41:55 Looking to hire - cell culture scientist work 43:55 Key experiences that will translate into the role 45:55 Cellular agriculture / specialization 48:10 How do ENCER models differ from CRISPR, Organoids, and Animal models in terms of simulating resistance (FanQ) 54:30 What is left to do / what he needs help with 58:45 Immunotherapy and landscape change for cancer treatment and cure 01:01:40 Next 5 years and Lowell offers to chase Nick 01:03:50 Handling burnout and mental health 01:07:40 Art / being creative / painting 01:12:05 What books is he reading and what he recommends 01:14:23 Foundation apple tv show 01:15:10 Retirement for Nick 01:16:55 Police brutality episode https://www.youtube.com/watch?v=WgKBIb6Zb5c 01:17:40 Non resistance life
The All Local Afternoon Update for Tuesday, September 26th, 2023
Featuring a slide presentation and related discussion from Dr Debra Richardson, including the following topics: Targeting folate receptor alpha in ovarian cancer; activity, tolerability and ongoing investigation of the antibody-drug conjugate (ADC) mirvetuximab soravtansine (0:00) Other ADCs under investigation for patients with ovarian cancer (20:05) Mechanism of action and activity of upifitamab rilsodotin (UpRi) for patients with pretreated ovarian cancer (23:27) Emerging strategies for patients with platinum-resistant ovarian cancer (29:53) Rationale for the discontinuation of clinical development of UpRi (33:17) CME information and select publications
In this episode of the DU Podcast, dedicated Arkansas outdoorsman and freelance videographer Austin Brown joins host and DUTV producer John Gordon. Together, they dive into the fascinating world of waterfowl hunting TV, shedding light on the intricate challenges that come with capturing the essence of this beloved outdoor sport on camera.www.ducks.org/DUPodcast
In this episode, Lisa is joined by Logan Church, the National Political Director of Catholic Vote. They discuss the controversy surrounding the FBI's targeting of Catholics and the lawsuit filed by Catholic Vote against the FBI. The conversation delves into the reasons behind the targeting, the leaked memo encouraging surveillance of Catholics, and the concerns about who might be targeted next. They also touch on the broader implications of the attacks on Catholics and traditional values, including the erosion of parental rights and the push for moral relativism. Church highlights Catholic Vote's efforts in voter education and advocacy. Listen to new episodes of The Truth with Lisa Boothe every Monday & Thursday.See omnystudio.com/listener for privacy information.
This episode reports on a retaliation threat against Canadian websites, the impact of the Dallas ransomware attack, and more
Welcome to America's leading higher education podcast where we talk trending legal, regulatory and compliance matters - EdUp Legal! YOUR host is Deborah Solmor In this episode, her guests are Saul Ewing partners Joe Lipchitz & Sandy Bilus. Listen in as they talk about the rise of litigation focused on data collection by consumer facing websites, including what information is being collected and how. They also discuss the legal theories behind these class action lawsuits and offer practical guidance for businesses related to risk mitigation. Listen in to #EdUpLegal A link to some additional resources: · Protecting Your Business From Recent Trend of Wiretap Lawsuits Targeting Companies With Consumer-Facing Websites · Massachusetts seeing wave of ‘session replay' suits Listen in each week to get the buzz on the trending higher education legal, regulatory, and compliance questions without the legalese. We make higher education LegalEASY. Join YOUR EdUp community at The EdUp Experience! We make Education YOUR business
In this episode, Lisa is joined by Logan Church, the National Political Director of Catholic Vote. They discuss the controversy surrounding the FBI's targeting of Catholics and the lawsuit filed by Catholic Vote against the FBI. The conversation delves into the reasons behind the targeting, the leaked memo encouraging surveillance of Catholics, and the concerns about who might be targeted next. They also touch on the broader implications of the attacks on Catholics and traditional values, including the erosion of parental rights and the push for moral relativism. Church highlights Catholic Vote's efforts in voter education and advocacy. Listen to new episodes of The Truth with Lisa Boothe every Monday & Thursday.Follow Clay & Buck on YouTube: https://www.youtube.com/c/clayandbuckSee omnystudio.com/listener for privacy information.
International students are being bombarded by scams asking for money and personal information — and authorities say the bad actors are using increasingly sophisticated techniques. - स्क्यामरहरुले पछिल्लो समय पैसा र व्यक्तिगत विवरणको चोरीका लागि अन्तर्राष्ट्रिय विद्यार्थीहरूलाई आफ्नो निशाना बनाइरहेको बताइएको छ। नयाँ प्रविधिहरूको प्रयोग गरी अस्ट्रेलियन बासिन्दा विशेष गरी अन्तर्राष्ट्रिय विद्यार्थीलाई निशाना बनाइरहेका छन्। यस वर्ष मात्र १२०० भन्दा बढी यस्ता ठगीका रिपोर्ट परिसकेका छन् भने करिब ८७ लाख डलरको ठगी भइसकेको दि नेशनल एन्टी स्क्याम सेन्टरले बताएको छ।
A round-up of the main headlines in Sweden on September 22nd, 2023. You can hear more reports on our homepage radiosweden.se, or in the app Sveriges Radio Play. Presenter: Dave RussellProducer: Michael Walsh
Facebook, with its massive user base and sophisticated advertising platform, remains a go-to platform for businesses looking to connect with their target audience. However, as the digital landscape continues to evolve, so do the strategies that work best for Facebook Ads.On today's show, we've got the lowdown on all things Facebook advertising with none other than Andrea Vahl, a multifaceted expert in the field. Andrea is a Facebook Advertising Specialist, Author, and Social Media Consultant, making her the perfect guest to unravel the mysteries of Facebook Ads for us.We'll discuss the challenges of ad tracking, harnessing the potential of Google Analytics, and explore the rationale behind broad versus niche targeting. Andrea will provide invaluable insights into Facebook's ad recommendations, optimizing advertising budgets, and the strategic advantages of lead ads.For those dedicated to mastering Facebook advertising and ensuring their campaigns resonate in a competitive space, this episode offers indispensable insights. Don't miss it!In this episode, you'll learn:How to set up a Facebook ads funnel for trackingThe secrets of effective testing and targetingTips for optimizing your ad campaignsRick Mulready's Links:Visit Rick's websiteDM Rick on InstagramFull episodes of The Art of Online Business Podcast on YouTubeKwadwo [QUĀY.jo] Sampany-Kessie's Links:Become a Facebook Ads Lead Gen Cheat Code Founding Member!Visit Kwadwo's website for Facebook Ads helpVisit Kwadwo's website to learn how he can hire a VA for you:https://quayjo.com/hireyourvaSay hi to Kwadwo on InstagramSubscribe to Kwadwo's YouTube channel to learn with him as he learns about personal finance, financial freedom, foreign languages and enjoying life!Andrea Vahl's Links:Visit Andrea websiteDM Andrea on InstagramSubscribe to Andrea's YouTube ChannelTimestamps:00:00 - Introduction03:14 - About Andrea Vahl08:19 - Tracking conversions13:25 - Using Google Analytics18:19 - Targeting strategies21:36 - Facebook ad budgeting30:19 - Running lead and sales ads35:22 - Tracking leads and revenue41:12 - Running ads during launches46:39 - Connect with Andrea VahlPlease support the podcast by giving an honest Rating/Review for the show on iTunes!Leverage QUĀY.jo's three years of Facebook Ads experience to double your leads and set up your lead gen ads in days (not weeks) with the confidence to lower your lead costs like an expert. Become a Founding Member of the Lead Gen Cheat Code Facebook Ads course.Visit https://quayjo.com/foundingmember to secure one of the remaining spots.
Flounder season is upon us! Here are a few tips on how to get bit even when the flounder fishing pressure is high! -Checkout Outdoors by Owner- https://go-obo.com/ -40% Off EyeStrike & Zman- Code: EC10 https://eyestrikefishing.com -Florida Fishing Products- https://www.floridafishingproducts.com -Temple Fork Outfitters- https://tforods.com -Bonafide Kayaks- https://bonafidefishing.com -Carolina First Mate- https://carolinafirstmate.com Do you love Eastern Current and want to help support us as well as gain access to tons of extra content that has never been released to the public? Donate through our PATREON Account! https://www.patreon.com/user?u=31609753&fan_landing=true Be Sure to checkout Eastern Current on Youtube, Facebook and Instagram! Book a Fishing Trip -Jud Brock - https://www.easternangling.com/ Book a Hunt -Jud Brock- https://www.easternwaterfowl.com/
In this week's episode, we discuss real-world evidence for CAR T cell therapy in older patients with diffuse large B-cell lymphoma, inhibiting endogenous anticoagulant pathways in congenital factor deficiencies, and finally targeting the HSP90 epichaperome in acute myeloid leukemia.
Multiple myeloma (MM) is a type of blood cancer that affects plasma cells, which are responsible for producing antibodies. MM is characterized by the accumulation of abnormal plasma cells in the bone marrow, leading to bone damage, kidney failure, anemia, and increased susceptibility to infections. MM is a heterogeneous disease with different subtypes and genetic mutations that affect the prognosis and response to treatment. Therefore, there is a need for new biomarkers and therapeutic targets that can improve the outcomes of MM patients. One of the potential targets that has recently emerged is the fatty acid binding protein (FABP) family. FABPs are proteins that bind and transport fatty acids, which are essential for energy production, cell signaling and membrane synthesis. FABPs are expressed in various tissues and organs, and have different roles depending on their location and type. There are nine members of the FABP family, but FABP5 seems to be the most relevant for MM. In a recent editorial paper, researchers Heather Fairfield and Michaela R. Reagan from Maine Health Institute for Research, University of Maine and Tufts University School of Medicine summarized previous findings from their 2023 study and the current evidence on the role of FABPs in MM. On June 19, 2023, their editorial was published in Oncotarget, entitled, “The hope for targeting fatty acid binding proteins in multiple myeloma.” Full blog - https://www.oncotarget.org/2023/09/21/targeting-fatty-acid-binding-proteins-in-multiple-myeloma/ Paper DOI - https://doi.org/10.18632/oncotarget.28437 Correspondence to - Michaela R. Reagan - Michaela.Reagan@mainehealth.org Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28437 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, multiple myeloma, FABPs, fatty acid binding proteins, immunoncology, pre-clinical discovery About Oncotarget Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science. To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: SoundCloud - https://soundcloud.com/oncotarget Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Media Contact MEDIA@IMPACTJOURNALS.COM 18009220957
In this episode, Victor Davis Hanson and cohost Jack Fowler talk about the IRS targeting the middle class, the new US border is northern Texas, illegal immigration, AOC's "spouse" getting perks, pornhustling candidate for the Virginia legislature, Manchin the artifact, and appeasing Iran.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Go to https://factormeals.com/stt50 and use code stt50 for 50% off
Tim, Phil, & Carter join Chef Andrew Gruel & Harrison Smith to discuss the UK admitting it's going after Russell Brand, allegations against Tim Ballard surfacing only after he announces a run for Senate, Howard Stern promising his listeners that he is woke, & NeuraLink announcing it's beginning human trials. Learn more about your ad choices. Visit megaphone.fm/adchoices
PeerView Family Medicine & General Practice CME/CNE/CPE Video Podcast
Go online to PeerView.com/FRX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Atopic dermatitis (AD) is a chronic disease that affects a significant portion of the US population. The current treatment paradigm for AD is complex, involving multiple active drugs tailored to different body parts, stages of the disease, and severity levels, in addition to moisturizers, bathing practices, and lifestyle recommendations. However, the effectiveness of certain available treatment options is limited because of concerns regarding efficacy, tolerability, and safety. In recent years, there have been significant advancements in the treatment of AD, including the approval of the first biologic agent and the ongoing clinical development of targeted therapies. In this activity, a panel of experts discuss the severity of AD across different patient populations, considering the chronic and heterogeneous nature of the disease, and the underlying pathophysiologic processes that contribute to the development of AD. In addition, they explore individualizing treatment for patients with moderate to severe AD, with a goal of minimizing and preventing flares. Upon completion of this activity, participants should be better able to: Diagnose the severity of AD across different patient populations, considering the chronic and heterogeneous nature of the disease; Describe underlying pathophysiologic processes that contribute to the development of AD, and provide rationale for the use of targeted biologic therapy; and Select appropriate treatment for patients with moderate to severe AD, including biologic agents as appropriate, according to recent clinical evidence and current guidelines, with a goal of minimizing/preventing flares
Go online to PeerView.com/FRX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Atopic dermatitis (AD) is a chronic disease that affects a significant portion of the US population. The current treatment paradigm for AD is complex, involving multiple active drugs tailored to different body parts, stages of the disease, and severity levels, in addition to moisturizers, bathing practices, and lifestyle recommendations. However, the effectiveness of certain available treatment options is limited because of concerns regarding efficacy, tolerability, and safety. In recent years, there have been significant advancements in the treatment of AD, including the approval of the first biologic agent and the ongoing clinical development of targeted therapies. In this activity, a panel of experts discuss the severity of AD across different patient populations, considering the chronic and heterogeneous nature of the disease, and the underlying pathophysiologic processes that contribute to the development of AD. In addition, they explore individualizing treatment for patients with moderate to severe AD, with a goal of minimizing and preventing flares. Upon completion of this activity, participants should be better able to: Diagnose the severity of AD across different patient populations, considering the chronic and heterogeneous nature of the disease; Describe underlying pathophysiologic processes that contribute to the development of AD, and provide rationale for the use of targeted biologic therapy; and Select appropriate treatment for patients with moderate to severe AD, including biologic agents as appropriate, according to recent clinical evidence and current guidelines, with a goal of minimizing/preventing flares
Start your free trial today: http://www.Squarespace.com/Phil & enter offer code “Phil” to get 10% off your first purchase! Go Buy http://WakeandMakeCoffee.com 50% OFF select orders! This new batch won't last long. Catch up on our latest PDS: https://youtu.be/OaCarcKyOGg?si=TUZnaWaOyJ7Yzcat Check out our daily newsletter! http://dailydip.co/pds Follow me on Instagram: https://www.instagram.com/phillydefranco/?hl=en – ✩ TODAY'S STORIES ✩ – 00:00 - Cops Under Investigation After Saying 11-Year-Old Victim Could be Arrested 01:36 - Lawsuits Allege Louisiana Police Held Detainees in Unmarked “Torture Warehouse” 03:12 - Britain Passes Expansive Online Safety Law, Prompts Privacy Concerns 06:10 - Colleges Increasingly Outsource Student Housing to Private Companies 09:30 - Sponsored by Squarespace 10:16 - The Universe Could be Nearly Twice as Old as We Thought 12:19 - Pennsylvania Will Start Automatic Voter Registration 14:10 - Anti-Affirmative Action Group Sues West Point 16:34 - Azerbaijan Launches Offensive Against Ethnic Armenians in NK 18:08 - Your Thoughts on Yesterday's Stories —————————— Produced by: Cory Ray Edited by: James Girardier, Maxx Enright, Julie Goldberg, Christian Meeks Art Department: William Crespo Writing/Research: Philip DeFranco, Brian Espinoza, Lili Stenn, Maddie Crichton, Star Pralle, Chris Tolve ———————————— #DeFranco #AndrewTate #TaylorSwift ————————————
Beau Martonik is joined by Joe Martonik and Johnny Stewart. They are getting ready for the season to kick off in Pennsylvania and discuss hunting from a saddle, outlooks on this season, the full moon, weather fronts, accessing stand sites, thermal tsunamis, targeting a specific buck, and much more! Topics: 00:00:00 - Start 00:05:11 - Johnny and Joe starting to hunt out of saddles more 00:14:39 - Using the saddle as a hybrid system 00:15:52 - Johnny trying different bows and switching to a Prime 00:19:28 - Outlook for this hunting season 00:33:19 - Does the full moon affect deer movement and the rut? 00:36:48 - Weather fronts affecting deer movement 00:42:55 - Early season deer hunting talk 00:50:59 - Hunting buck bedding 00:53:12 - Access when trying to hunt scrapes in October 00:57:18 - Thermal Tsunamis 00:59:20 - More on accessing your stand 01:06:47 - Targeting a Specific Buck 01:16:39 - Hunting core area prediction days on Spartan Forge 01:21:43 - Hunt plans 01:28:30 - Goals tailored to you. Hunt the way that makes you happy. Note** timestamps might be off by roughly 4 minutes on the audio version due to ad length changes. Resources: GoWild: Beau Martonik (East Meets West Hunt) Instagram: @eastmeetswesthunt @beau.martonik @thejohnnystewart Facebook: East Meets West Outdoors Website/Apparel/Deals: https://www.eastmeetswesthunt.com/ YouTube: Beau Martonik - https://www.youtube.com/channel/UCQJon93sYfu9HUMKpCMps3w Partner Discounts and Affiliate Links: https://www.eastmeetswesthunt.com/partners Amazon Influencer Page https://www.amazon.com/shop/beau.martonik Learn more about your ad choices. Visit megaphone.fm/adchoices
Kash Patel files lawsuit against the FBI and Department of Justice after the agencies obtained a subpoena for his personal records in November 2017 during his time working as a investigator for House Intelligence Committee during its investigation into the DOJ's conduct during Crossfire Hurricane, now referred largely as RussiaGate. Patel was unaware of the subpoena until December 2022, when he was notified by Google about it. Patel says in 2017, that move, in and of itself was so shocking, that idea that essentially the Attorney General for the whole RussiaGate investigation threatened the chairman of the House Intelligence Committee and his senior staffers, because we were uncovering corruption that preceded them. And what we would learn later is they were in on the corruption cover up. That's why they threatened us, it wasn't a lie.” Additional interview Texas Representative Steve Toth over the acquittal of Ken Paxton. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this week's MBA Admissions podcast we began by discussing the upcoming Round 1 deadlines for this new season; for this week NYU / Stern, IESE, Cornell / Johnson and Chicago / Booth all have their Round 1 MBA application deadlines; Duke / Fuqua is scheduled to release interview invites for its Early Action round. Graham highlighted our next Essay Insights series, which continues on Wednesday of this week, with CMU / Tepper, Columbia, Georgetown / McDonough, Texas / McCombs and UNC / Kenan Flagler; these events are very popular and bring together the leading MBA programs to talk about their admissions essay topics. Signups are here: https://bit.ly/cafallessays Graham then shared some insights from a recently published Adcom Q&A from Shelly Heinrich at Georgetown McDonough. Our final discussion focused on the recently published MBA class profile for Duke / Fuqua. Their class profile matched some of the observations we identified with the class profile of UCLA / Anderson (the class profile we discussed on last week's show). Fuqua is reporting a smaller class size, while keeping the quality of the class close to constant. We did also discuss the ranges of test scores and GPAs, but we think candidates would prefer to know the medians, or both. As usual, for the candidate profile review portion of the show, Alex selected three ApplyWire entries: This week's first MBA admissions candidate is from India - and therefore is over-represented in the pool. At the same time, they appear to have very good numbers and strong work experience, balanced by decent volunteer activities outside of work. They are not over-reaching with their target programs in the first round, and we wonder if they should have targeted 1-2 M7 level programs. This week's second MBA candidate is also a strong candidate, based in the U.S. An All-American athlete from a top liberal arts college, they are working in consulting (MBB) with a focus on the climate. Their only weaker area is a slightly lower-than-average-for-top-programs GRE score. Should they apply in Round 1 with this score (325) or delay to Round 2 with a higher score. We think the latter might be a good strategy, or at least split the applications over two rounds. The final MBA candidate is an entrepreneur who has a great GRE score (333) but a poor GPA (2.9). While they have an upward trend for the GPA, they will need to use the optional essay to add context. They might also consider taking Business Fundamentals, or other similar options to show that they are prepared and committed to the academic aspect of the MBA experience. This episode was recorded in Paris, France and Cornwall, England. It was produced and engineered by the fabulous Dennis Crowley in Philadelphia, USA. Thanks to all of you who've been joining us and please remember to rate and review this show wherever you listen!
Interview with Alan Carter, President & CEO of Cabral Gold Inc.Our previous interview: https://www.cruxinvestor.com/posts/cabral-gold-tsxvcbr-5m-funds-pfs-improves-build-out-timeframe-3315Recording date: 14th September 2023Cabral Gold is advancing the Cuiú Cuiú gold project in northern Brazil, with the aim of bringing low-cost oxide gold production online rapidly. In a recent interview, President and CEO Alan Carter outlined plans to complete a pre-feasibility study on the oxide cap by January 2023 and potentially start construction by Q2 2023.With approximately $7 million in the bank, Cabral is funded to complete the pre-feasibility study on the oxide zone. This oxidized material sits above the primary gold resource and contains over 60 meters of free-digging material that can be processed via simple heap leach methods. By focusing first on the oxide cap, Cabral aims to generate early cash flow with low initial capex requirements.The larger Cuiú Cuiú project contains 1.2 million ounces of indicated and inferred hard rock gold resources. However, developing the full potential of the project will require substantially more capital investment. Targeting the oxide zone first is a lower-risk, faster route to production and revenue within 12-18 months.Cuiú Cuiú is located next to G Mining's large-scale gold project, which recently commenced construction. G Mining's development has improved infrastructure in the region and heightened attention on the district's potential. During historical gold rushes, streams on G Mining's land produced 200,000 ounces, while 2 million ounces were mined from Cabral's project area.With a current market cap around $25 million and approximately 15 million ounces in enterprise value per ounce, Cabral believes it is deeply undervalued. The company is engaged in project financing discussions to fund construction of the starter oxide mine, which requires relatively modest capital expenditure given the simple process flow sheet.Advancing the oxide zone provides a clear pathway to near-term cash flow for Cabral. It also de-risks future development of the full Cuiú Cuiú project and its multi-million ounce potential. For investors, the company offers speculative exposure to high-grade gold development in a proven region of Brazil.—View Cabral Gold's Company Profile: https://www.cruxinvestor.com/companies/cabral-goldSign up for Crux Investor: https://cruxinvestor.com
UR goes live to breakdown week 3 of the 2023 CFB season. -Tennessee looked awful. -Did Billy Napier save his job in the Swamp today? -What a win for Mizzou! -What should we do with Colorado? -Alabama may just not be very good....who will be their QB for the remained of 2023? -Targeting remains the worst rule in CFB -Oklahoma DOMINATED....are they for real? -Are we concerned about Texas' performance against Wyoming? -That and MUCH MUCH MORE! Thanks to our SPONSORS! Visit highnoonspirits.com before your next tailgate to find a pack near you. Find your next possibility on https://Cars.com. Where to next? Go to https://BarstoolGM.com and useYou can find every episode of this show on Apple Podcasts, Spotify or YouTube. Prime Members can listen ad-free on Amazon Music. For more, visit barstool.link/unnecroughness
Yesterday, Ukraine hit targets in Crimea, damaging or destroying one kilo-class Russian sub and one landing ship. The missiles used were StormShadows from the UK and the targeting was from the US Pentagon. How soon until Russia strikes back at increasingly direct NATO/US involvement in the war? Also today: too little too late - the Pentagon suddenly develops an interest in where the money to Ukraine is going. Finally - Agent Orange 2.0? US to "defoliate" Asian jungles to prepare for war with China.
The Wounded Blue with Lt. Randy Sutton – American Law Enforcement Officers are being prosecuted by “activist” District Attorneys and Prosecutors at a rate never before seen in our nation. These prosecutions are destroying the lives of the officers emotionally and financially. Officer James Fotis founded The National Center for Police Defense to help...
The Wounded Blue with Lt. Randy Sutton – American Law Enforcement Officers are being prosecuted by “activist” District Attorneys and Prosecutors at a rate never before seen in our nation. These prosecutions are destroying the lives of the officers emotionally and financially. Officer James Fotis founded The National Center for Police Defense to help...
South Dakota Guides and Tournament fisherman Cody and Tyler talk about targeting big walleye and what it takes to win tournaments. We also talked about Walleye Nation Creations and how their crank baits are tried and true. Thanks guys that was a lot of fun.
On this Thursday breakdown, we are covering some listener Q&A as well as some updates on Andrew's hunting club! Subjects include: Targeting creek crossings for big bucks The big 10 Andrew is chasing this year Tactics for hunting ridge tops Is Jacob's stage name Oliver Anthony? Best way to beat mosquitos and other bugs in early season Mentoring a hearing-impaired hunter. To visit Christensen Arms and learn how to CLAIM up to $750 in free gear, click here - https://l.linklyhq.com/l/1tadE Got a question for the show? Submit a listener Q&A form Use the promo code “southern” for a discount on your OnX Hunt membership here - https://try.onxmaps.com/hunt/app/hunt-smarter/?gclid=Cj0KCQiA7bucBhCeARIsAIOwr-_sBLib6xC3ibT5BMlTrBUdWdpGYOWOZ_06eZhJajTmMKne7e00Rd4aAtldEALw_wcB Save 10% on your next Vortex Optics order at MidwayUSA.com using the Promo Code "SOUTHERN1023" - https://www.midwayusa.com/ NEW Trace system from First Lite - New: Trace System Have you tagged a deer using something you heard on the show? Submit your listener success story here - Share Your Story Here Want to help keep the show on the air, and get some bonus content? Join our patreon - https://www.patreon.com/thesouthernoutdoorsmen Learn more about your ad choices. Visit megaphone.fm/adchoices
Facebook continues to be an effective platform for promoting your online business. This is why we have decided to dive deep into the world of Facebook Ads today. If you want Kwadwo to troubleshoot your ads, fix your sales funnel or are considering hiring someone to manage your ads, visit Kwadwo's website.In this episode, we'll share expert answers that will help you to drive positive results. We discuss the right mindset in budgeting for your Facebook Ads to see results, the power of targeting secondary audiences, and the importance of a simplified testing methodology. But we're not here just to talk about Facebook Ads concepts. Instead, we'll answer your most pressing questions by citing practical examples and techniques. We'll also go through a step-by-step demonstration of how to efficiently test your ads.If you want to maximize the power of Facebook Ads for your online business, this episode offers a wealth of valuable tips, insights, and strategies. Join us as we answer your burning questions and uncover the secrets to achieving success with Facebook Ads. In this episode, you'll learn:How to determine your ideal Facebook Ads budget based on dataThe power of targeting secondary audiences A step-by-step process for simplified testing and optimizing your Facebook AdsRick Mulready's Links:Visit Rick's websiteDM Rick on InstagramFull episodes of The Art of Online Business Podcast on YouTubeKwadwo [QUĀY.jo] Sampany-Kessie's Links:Visit Kwadwo's website for Facebook Ads helpSay hi to Kwadwo on InstagramSubscribe to Kwadwo's YouTube channel to learn with him as he learns about personal finance, financial freedom, foreign languages and enjoying life!Timestamps:00:00 — Introduction03:25—Are Facebook ads still viable in 2023?06:27 — Why Rick hates the term ‘tripwire'10:16 — Choosing SLO funnels and focusing on leads16:30 —Why Facebook wants course creators to succeed20:57 —Lower cost, higher profitability21:57 — Smarter AI learns from data to target ads26:53 —Simple math to guide your Facebook ads31:02—Targeting secondary audiences 33:53 — AI tools for research38:30 — Empathizing with the right questions42:25— Episode wrap-upPlease support the podcast by giving an honest Rating/Review for the show on iTunes! Head to Kwadwo's website https://quayjo.com tohave Kwadwo review your ads, ads strategy or funnel or tobook a call to talk with him about his ads management services.
In today's episode of "Beyond A Million", join Brad and Brian on an exciting entrepreneurial journey! Learn how to succeed in business by using your strengths, balancing work and life, and improving continuously. Brian shares smart tips for selling high-ticket products, focusing on happy customers, and shifting from coaching individuals to helping companies with purpose-driven leadership. Discover why matching your company's values with your employees' goals is vital and why being tough and learning from mistakes matter. Stay focused, don't get sidetracked by new opportunities, and make your entrepreneurial dreams come true with these valuable insights! Brian Bosché is the CEO of The Millennial Solution and a former national journalist. He started his first successful company at the age of 26 with a laptop, a phone, and 50 dollars. Brian is an expert on purpose at work and a consultant who helps business leaders and companies (big and small) keep their top talent. He has personally consulted Fortune 500 companies and A-list celebrities and designed strategies for leaders looking to remain on top in this competitive talent market. Brian's clients include some of America's top companies, and he has helped them cut massive losses related to employee churn. HIGHLIGHTS: Nurturing Passion and Strengths Throughout Business Growth Effective Task Delegation for CEOs The Importance of Visionary Leadership Teams Balancing Work and Life While Embracing Continuous Learning Prioritizing Strengths and Making Sacrifices for Success Aligning Company Values with Employee Goals Building Resilience through Learning from Mistakes Personal Growth as an Entrepreneurial Imperative SOCIAL MEDIA Website URL: https://www.brianbosche.com Social Media URL: Brian Bosché's FB
What's Trending: More crime targeting elderly victims, Whoopi Goldberg has COVID and a surgically removed tumor was lost. // Biden's poll numbers are absolutely tanking. // Environmentalists booed after protest halts U.S. Open match. See omnystudio.com/listener for privacy information.
0:00 Intro 1:02 Corporate Suicide 20:10 Transgender Cultists 31:41 Bioweaponized Mosquitoes 1:18:45 Interview with Josh Yoder from US Freedom Flyers - Liberty safe commits corporate suicide by colluding with FBI against its own customers - The FBI is a TERRORIST organization carrying out POLITICAL persecutions across America - BOYCOTT #LibertySafe and never buy their products again - #RFK Jr. says the CIA runs Rolling Stone, Daily Beast, Wash Post and other controlled media - Courageous woman blasts #transgender CULTISTS with the truth about "trans women," child mutilations and more - Bioweaponized mosquitoes are being dropped on migrant camps in #Panama - Malaria + Encephalitis (brain swelling) are current symptoms - Treasonous Alejandro Mayorkas FUNDED the migration invasion camps in #Darien Gap - Migrant INVADERS are being sickened before they make their way to the United States - Human vessels / carriers for the next round of biological warfare against the American people before 2024 election - USDA and FDA placing heavy new restrictions on food imports to worsen #famine and #starvation - Former Malaysian PM warns of the West's global #depopulation scheme, involving coercion, invasions, revolutions - The #dollar will collapse into hyperinflation as the Fed must print currency to buy up US #debt - Expect food prices to nearly DOUBLE in the next 12 months - One likely scenario is the collapse of the United States' centralized D.C. government - Regional nation states will rise up and self-organize - Those holding dollars will lose everything; those holding #gold or #silver will preserve their assets - Full interview with Josh Yoder from US Freedom Flyers, about commercial air pilots vs. #vaccine mandates For more updates, visit: http://www.brighteon.com/channel/hrreport NaturalNews videos would not be possible without you, as always we remain passionately dedicated to our mission of educating people all over the world on the subject of natural healing remedies and personal liberty (food freedom, medical freedom, the freedom of speech, etc.). Together, we're helping create a better world, with more honest food labeling, reduced chemical contamination, the avoidance of toxic heavy metals and vastly increased scientific transparency. ▶️ Every dollar you spend at the Health Ranger Store goes toward helping us achieve important science and content goals for humanity: https://www.healthrangerstore.com/ ▶️ Sign Up For Our Newsletter: https://www.naturalnews.com/Readerregistration.html ▶️ Brighteon: https://www.brighteon.com/channels/hrreport ▶️ Join Our Social Network: https://brighteon.social/@HealthRanger ▶️ Check In Stock Products at: https://PrepWithMike.com