Podcasts about AML

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Best podcasts about AML

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Latest podcast episodes about AML

Integrative Cancer Solutions with Dr. Karlfeldt
Finding Strength: Mollie Kallen's Journey from AML Diagnosis to Cancer Advocacy

Integrative Cancer Solutions with Dr. Karlfeldt

Play Episode Listen Later Aug 13, 2025 51:11


Mollie Kallen, a former elementary educator and counselor, shares her deeply personal journey after being unexpectedly diagnosed with acute myeloid leukemia (AML) in April 2023. Her story begins with the shock of diagnosis and the rapid transition from her professional life to becoming a full-time patient. Mollie describes the overwhelming emotions and uncertainty she faced, highlighting the importance of resilience and adaptability in the face of life-altering news. Throughout her treatment, which included multiple rounds of chemotherapy and a bone marrow transplant, Mollie emphasizes the critical role of self-advocacy. She discusses how taking an active role in her care—asking questions, seeking second opinions, and understanding her treatment options—empowered her to make informed decisions. Mollie encourages other patients to speak up and be proactive, stressing that self-advocacy can significantly impact outcomes and overall well-being. Mollie also underscores the value of building a strong support system, or a “village,” during cancer treatment. She credits her family, friends, and fellow patients for providing emotional and practical support throughout her journey. This network helped her navigate the physical and psychological challenges of treatment, offering encouragement, companionship, and assistance with daily tasks. Mollie's experience demonstrates that no one should face cancer alone, and that community is a vital resource for healing. In addition to her personal story, Mollie advocates for better communication between patients and healthcare providers. She believes that open, honest dialogue is essential for effective care and encourages patients to utilize available resources such as counseling, yoga, and music therapy. Mollie highlights the need for practical tools and information to help patients and caregivers manage the complexities of cancer treatment, from understanding medical terminology to coping with side effects. Looking ahead, Mollie is channeling her experiences into advocacy and education. She is writing a book aimed at guiding patients and caregivers through the cancer journey, offering insights, encouragement, and practical advice. Her goal is to empower others to navigate their own diagnoses with confidence and hope, ensuring that no one feels isolated or unprepared as they face the challenges of cancer.Mollie Kallen recounts her unexpected diagnosis with acute myeloid leukemia (AML) in April 2023 and the immediate upheaval it caused in her life.She highlights the importance of self-advocacy and being proactive in medical decision-making during cancer treatment.Building a supportive "village" of family, friends, and fellow patients was crucial to her emotional and practical well-being.Mollie advocates for open communication with healthcare providers and the use of resources like counseling, yoga, and music therapy.She is writing a book to help guide other patients and caregivers through the complexities of cancer treatment, drawing from her own experiences.----Grab my book A Better Way to Treat Cancer: A Comprehensive Guide to Understanding, Preventing and Most Effectively Treating Our Biggest Health Threat - https://www.amazon.com/dp/B0CM1KKD9X?ref_=pe_3052080_397514860 Unleashing 10X Power: A Revolutionary Approach to Conquering Cancerhttps://store.thekarlfeldtcenter.com/products/unleashing-10x-power-Price: $24.99-100% Off Discount Code: CANCERPODCAST1Healing Within: Unraveling the Emotional Roots of Cancerhttps://store.thekarlfeldtcenter.com/products/healing-within-Price: $24.99-100% Off Discount Code: CANCERPODCAST2----Integrative Cancer Solutions was created to instill hope and empowerment. Other people have been where you are right now and have already done the research for you. Listen to their stories and journeys and apply what they learned to achieve similar outcomes as they have, cancer remission and an even more fullness of life than before the diagnosis. Guests will discuss what therapies, supplements, and practitioners they relied on to beat cancer. Once diagnosed, time is of the essence. This podcast will dramatically reduce your learning curve as you search for your own solution to cancer. To learn more about the cutting-edge integrative cancer therapies Dr. Karlfeldt offer at his center, please visit www.TheKarlfeldtCenter.com

Research To Practice | Oncology Videos
Acute Myeloid Leukemia — An Interview with Dr Jorge Cortes on Optimal Management of FLT3 and IDH1/2 Mutations

Research To Practice | Oncology Videos

Play Episode Listen Later Aug 12, 2025 43:02


Featuring an interview with Dr Jorge Cortes, including the following topics: Overview of common molecular profiles in newly diagnosed acute myeloid leukemia (AML) (0:00) Clinical presentation of AML with a FLT3 mutation; implications of clinical data from the Phase III RATIFY trial of the FLT3 inhibitor midostaurin (5:38) Potential incorporation of a FLT3 inhibitor with azacitidine/venetoclax for transplant-ineligible patients with FLT3-mutant AML (10:32) Clinical benefit with quizartinib for patients with FLT3-like genetic profile; selection of FLT3 inhibitor as a component of initial therapy for individuals with AML with a FLT3-ITD mutation (14:04) Overview of FDA-approved IDH inhibitors enasidenib, ivosidenib and olutasidenib; differentiation syndrome as a class effect of IDH inhibitors in AML (20:31) Case: A woman in her late 60s with newly diagnosed AML with FLT3-ITD and NPM1 mutations receives 7+3 chemotherapy in combination with quizartinib (31:07) Case: A patient in their late 70s with multiple comorbidities and newly diagnosed IDH1-mutant AML (37:53) CME information and select publications

Every Day Oral Surgery: Surgeons Talking Shop
Hematology Series – Leukemia Types, Diagnosis, and Treatment Modalities (with Drs. Andrew Jenzer and Maxwell Lloyd)

Every Day Oral Surgery: Surgeons Talking Shop

Play Episode Listen Later Aug 11, 2025 80:41


Welcome back to part three of our hematology series here at Every Day Oral Surgery! Today, Drs. Andrew Jenzer and Maxwell Lloyd join Dr. Stucki to discuss all things leukemia. Tuning in, you'll hear all about the different kinds of leukemia, how we differentiate between them, symptoms of leukemia, and so much more! We delve into specific characteristics of acute myelogenous leukemia and how to avoid leukocytosis before discussing the role chemotherapy plays in treating different types of leukemia and the two different kinds of transplants these patients can have. We go on to discuss chronic myelogenous leukemia, the different phases associated with it, how chemotherapeutic medications may affect oral surgery procedures, how acute lymphocytic leukemia differs from other forms of leukemia, and how it's treated. Lastly, we dive into the most common kind of leukemia, chronic lymphocytic leukemia, the staging and prognosis of it, and so much more. This episode is jam-packed with important information that you don't want to miss out on, so be sure to press play now and tune in for the next episode!Key Points From This Episode:Welcoming today's guest, Dr. Maxwell Lloyd. A breakdown of some of the vocabulary doctors use in hematological care. What leukemia is and how we classify what kind of leukemia a patient has. Some general characteristics of all kinds of leukemia. Dr. Jenzer breaks down the characteristics of myeloid leukemia.What leukocytosis is, why it's so dangerous, and how we prevent it. How doctors treat AML (acute myelogenous leukemia). Using chemotherapy to treat leukemia and why it isn't enough on its own. The differences between autologous and allogeneic transplants. Breaking down CML (chronic myelogenous leukemia) and its phases.What ALL (acute lymphocytic leukemia) is and treatment options for it. We dive into the most common form of leukemia, CLL (chronic lymphocytic leukemia). Some important things to know about BTK inhibitors. Links Mentioned in Today's Episode:Dr. Andrew Jenzer — https://www.quintessence-publishing.com/usa/en/author/3920767/jenzer-andrew-clark Dr. Maxwell Lloyd Google Scholar — https://scholar.google.com/citations?user=D0agka0AAAAJ&hlSr. Louis OMFS Review — https://stlomfsreview.com/ Everyday Oral Surgery Website — https://www.everydayoralsurgery.com/ Everyday Oral Surgery on Instagram — https://www.instagram.com/everydayoralsurgery/ Everyday Oral Surgery on Facebook — https://www.facebook.com/EverydayOralSurgery/Dr. Grant Stucki Email — grantstucki@gmail.comDr. Grant Stucki Phone — 720-441-6059

AML Conversations
Cultural Racketeering, Crypto Kiosks, and the De-Banking Debate

AML Conversations

Play Episode Listen Later Aug 8, 2025 23:13


In this week's TWIA episode, John Byrne and Joe McNamara cover critical developments in financial crimes prevention across multiple jurisdictions. Cultural Racketeering Crisis Insights from a recent Atlantic Council program reveal Russia's systematic assault on Ukraine's cultural heritage: 200 million books destroyed, 35,000 artifacts stolen, and 2 million artifacts lost. Russian museum officials are personally complicit, prompting President Zelenskyy to issue sanctions against museum directors. Experts highlight AI's growing role in tracking stolen cultural property. Regulatory Updates FinCEN delays the investment advisor AML rule until 2028, citing deregulatory priorities despite acknowledging ongoing illicit finance risks. The President's working group releases digital asset market recommendations, while FinCEN warns about crypto kiosks being used for scams targeting older adults. International Developments The IMF's Canada financial stability assessment raises concerns about banking oversight gaps. New UK guidance addresses Russian sanctions evasion, while a British solicitor faces fines for AML failures in an Azerbaijan-linked property deal, highlighting ongoing gatekeeper compliance debates. The De-Banking Controversy Analysis of the proposed executive order targeting banks for alleged political discrimination. John Byrne challenges "Operation Choke Point 2.0" claims, emphasizing that banks make legitimate risk-based decisions considering credit worthiness and regulatory requirements. Discussion includes potential implications for suspicious activity reporting. Additional Coverage John Oliver's examination of deferred prosecution agreements in corporate crime cases provides context on this controversial prosecutorial tool's AML applications.

DACOM Digital
MiCA Masters: Surviving MICA in Poland: Compliance Tips and Hard Lessons

DACOM Digital

Play Episode Listen Later Aug 7, 2025 56:28


Łukasz Jabkowski and Maciej Grzegorczyk, attorneys at law at Kanga, reveal how they're preparing for MiCA amid Poland's delayed local law and strict AML oversight. From Travel Rule compliance to market abuse prevention, this episode is a must-hear for CASPs navigating high-risk jurisdictions.

The Laundry
Greatest Hits: A European fintech exposed as a billion dollar fraud

The Laundry

Play Episode Listen Later Aug 7, 2025 40:24


As a summer treat, we're bringing you some of the *top performing* episodes of The Laundry to date!This is a story about the wild rise and crushing fall of the tech giant, Wirecard, that was exposed as a billion dollar accounting fraud. It raises big questions about corporate fraud, money laundering and the need for strong financial regulations.In this episode (originally aired July 2022) your expert hosts, Marit Rodevand and Fredrik Riiser, are joined by Dan McCrum, investigative reporter and author of Money Men, to discuss: how a European fintech was exposed as a billion dollar fraudThe panel break down: Dan's investigations into Wirecard, the rollercoaster impact on his life, and what lessons have been learned from this case.Subscribe to our newsletter, Fresh Laundry, here____________________________________The Laundry podcast explores the complex world of financial crime, anti-money laundering (AML), compliance, sanctions, and global financial regulation.Hosted by Marit Rødevand, Fredrik Riiser, and Robin Lycka, each episode features in-depth conversations with leading experts from banking, fintech, regulatory bodies, and investigative journalism.Tune in as we dissect headline news, unpack regulatory trends, and examine the real-world consequences of non-compliance — all through a uniquely compliance-focused lens.The Laundry is proudly produced by Strise.Get in touch at: laundry@strise.ai The views, opinions, and statements expressed by guests of this podcast are solely their own and do not necessarily reflect the views, opinions, or positions of the podcast hosts, The Laundry team, or Strise. Hosted on Acast. See acast.com/privacy for more information.

Halal Money Matters
Episode 43: Scams and Schemes

Halal Money Matters

Play Episode Listen Later Aug 4, 2025


Our guest David Skade is a Financial Crime Executive and has over 20 years experience in risk management and financial crime prevention. He joins host Monem Salam to discuss the complexities of online scams, focusing on anti-money laundering (AML) regulations, affinity marketing, and how scammers play on sentiment and greed to exploit consumers.

iGaming Daily
Ep 573: KYC, Tech, and Women in Gaming, with Stake's Bárbara Teles

iGaming Daily

Play Episode Listen Later Aug 4, 2025 23:03


Welcome to iGaming Daily's 'Road to Lisbon', a limited  series spotlighting the standout themes and expert insights featured at the SBC Summit Lisbon, happening from September 16–18. In this episode, SBC Noticias's Business Journalist, Ana Maria Menezes speaks with Bárbara Teles, Legal and Compliance Director at Stake Latin America and Co-Founder of AMIG (Women in Gaming Association in Brazil). Together, they explore the panel topic “KYC: Lessons Out of Industry – What Can Tech Teach Us?”, offering listeners a strategic preview into how Know Your Customer practices from outside the gambling sector can elevate compliance within iGaming.Barbara dives deep into how technology-driven KYC models from sectors like banking can revolutionise fraud prevention, customer verification, and anti-money laundering efforts in betting. Drawing on Brazil's Pix payment system, she explains how speed, traceability, and user data insights can set a new compliance benchmark. However, adapting these fast-moving, app-based solutions to the rigor of gambling regulations poses unique challenges, from age verification to source of funds checks.The conversation also shines a light on diversity and accessibility in compliance technology. Barbara addresses Brazil's diverse user base, calling for multi-channel KYC strategies that extend beyond biometrics. Additionally, the episode amplifies the voice of women in gaming, spotlighting Barbara's leadership at Stake LatAm and the impactful work of AMIG and SBC's Women Empowerment Initiative.Host: Ana Maria MenezesGuest: Bárbara TelesProducer: Anaya McDonaldEditor: James RossiGaming Daily is also now on TikTok. Make sure to follow us at iGaming Daily Podcast (@igaming_daily_podcast) | TikTok for bite-size clips from your favourite podcast. Finally, remember to check out Optimove at https://hubs.la/Q02gLC5L0 or go to Optimove.com/sbc to get your first month free when buying the industry's leading customer-loyalty service.

Seize & Desist
Ep. 20: Global Standards, Local Challenges: Navigating FATF Compliance

Seize & Desist

Play Episode Listen Later Aug 1, 2025 39:29


In this episode, host Aidan Larkin delves into the intricate world of FATF compliance with Liz Lees, the former national coordinator for the Cayman Islands. They explore the unique challenges smaller jurisdictions face in aligning with global standards, emphasizing the pivotal role of asset recovery. Join us as Liz shares her insights on building effective compliance frameworks and overcoming resource constraints. As Aidan and Liz unpack the complexities of compliance in these unique environments, discover how these financial hubs balance the demands of international regulations with the need to preserve their local integrity. Timestamps00:00 - Introduction 05:12 - Understanding FATF Compliance 12:45 - Challenges in Smaller Jurisdictions 20:30 - The Role of Asset Recovery 28:15 - Building Effective Frameworks 35:50 - Overcoming Resource Constraints 42:00 - Balancing Global Standards and Local Integrity 50:10 - Conclusion and Key Takeaways About our Guest Liz Lees is a seasoned legal counsel and former National Coordinator to the Anti-Money Laundering Steering Group in the Cayman Islands. With extensive experience in financial compliance, Liz has been instrumental in shaping effective frameworks for smaller jurisdictions. As the co-founder of Claritas Legal, Liz specialises in regulatory law and financial crime, advising governments, law enforcement agencies, and supervisory bodies on compliance with FATF standards. Key Takeaways Understanding FATF Standards: Liz Lees explains the importance of FATF standards in shaping global financial compliance and the role they play in asset recovery. Challenges in Smaller Jurisdictions: The discussion highlights the unique challenges smaller jurisdictions face in implementing effective financial compliance frameworks. The Evolving Landscape of Financial Crime: Insights into how financial crime is evolving, particularly with the rise of digital assets and the need for updated compliance measures. Importance of Coordination: Emphasizes the need for coordinated efforts among governments, law enforcement, and financial institutions to effectively combat financial crime. Resources Mentioned FATF Official Website FATF's Recommendations Recent FATF Mutal Evaluation Reports Stay Connected Dive deeper into the world of asset recovery with Seize & Desist. Subscribe for exclusive insights into the stories that are redefining asset recovery. Disclaimer Our podcasts are for informational purposes only. They are not intended to provide legal, tax, financial, and/or investment advice. Listeners must consult their own advisors before making decisions on the topics discussed. Asset Reality has no responsibility or liability for any decision made or any other acts or omissions in connection with your use of this material. The views expressed by guests are their own and their appearance on the program does not imply an endorsement of them or any entity they represent. Views and opinions expressed by Asset Reality employees are those of the employees and do not necessarily reflect the views of the company. Asset Reality does not guarantee or warrant the accuracy, completeness, timeliness, suitability or validity of the information in any particular podcast and will not be responsible for any claim attributable to errors, omissions, or other inaccuracies of any part of such material. Unless stated otherwise, reference to any specific product or entity does not constitute an endorsement or recommendation by Asset Reality.

AML Conversations
Investigations, Bank Records, and Cooperation: The Keys to Following the Money

AML Conversations

Play Episode Listen Later Jul 31, 2025 32:30


David Tyree, Senior Advisor for Financial Crime Detection and AML for Valid 8, shares his views on the most essential ways to utilize bank data gleaned from his decades at DEA to his current work.

Cell & Gene: The Podcast
Navigating the Journey to Safer Stem Cell Therapies with Orca Bio's Nate Fernhoff

Cell & Gene: The Podcast

Play Episode Listen Later Jul 31, 2025 33:17


We love to hear from our listeners. Send us a message.Cell & Gene: The Podcast Host, Erin Harris, talks to Orca Bio CEO and Co-Founder Nathaniel Fernhoff as he recounts the company's origins and evolution, tracing its roots to pioneering stem cell research at Stanford University and Dr. Irv Weissman's lab. Seeking to create safer, more effective cures for blood cancers such as AML, ALL, and MDS, Orca Bio developed high-precision cell therapies that utilize purified regulatory T cells and stem cells to minimize complications, such as graft-versus-host disease. Orca Bio spun out of academia to establish its own scalable production platform and clinical pipeline, and Fernhoff explains Orca's flagship product, Orca T, which recently achieved a pivotal milestone by outperforming standard stem cell transplants in a Phase 3 trial.Subscribe to the podcast!Apple | Spotify | YouTube Visit my website: Cell & Gene Connect with me on LinkedIn

Blood Podcast
Hematopoietic stem cells with enhanced transplantability, ruxolitinib for refractory macrophage activation syndrome, and magrolimab in newly diagnosed acute myeloid leukemia

Blood Podcast

Play Episode Listen Later Jul 31, 2025 18:56


In this week's episode we'll learn more about enhanced transplant characteristics; targeting the JAK-STAT pathway with ruxolitinib in patients with adult-onset Still's disease and macrophage activation syndrome; and a pair of trials demonstrating lack of benefit for the anti-CD47 monoclonal antibody magrolimab in newly diagnosed acute myeloid leukemia.Featured ArticlesHeterogeneity of high-potency multilineage hematopoietic stem cells and identification of “Super” transplantabilityRuxolitinib targets JAK-STAT signaling to modulate neutrophil activation in refractory macrophage activation syndromeMagrolimab plus azacitidine vs physician's choice for untreated TP53-mutated acute myeloid leukemia: the ENHANCE-2 studyThe ENHANCE-3 study: venetoclax and azacitidine plus magrolimab or placebo for untreated AML unfit for intensive therapy

The Laundry
Greatest Hits: Is the EU's UBO ruling a gift to criminals?

The Laundry

Play Episode Listen Later Jul 31, 2025 41:11


As a summer treat, we're bringing you some of the *top performing* episodes of The Laundry to date! The EU's Ultimate Beneficial Ownership ruling made headlines all over Europe. It appeared to be a major win for those who think public UBO registers infringe on the right to privacy – but it also has massive consequences for financial criminals too. In this episode, originally aired December 2022, your expert host, Marit Rodevand, is joined by Thom Townsend, Executive Director of OpenOwnership, to discuss: Is the EU's UBO ruling a gift to criminals?The pair break down: the ruling from the Court Justice of the European Union, the right to privacy vs. criminality, and the impact of AML6 to potentially override the ruling. Subscribe to our newsletter, Fresh Laundry, here.____________________________________The Laundry podcast explores the complex world of financial crime, anti-money laundering (AML), compliance, sanctions, and global financial regulation.Hosted by Marit Rødevand, Fredrik Riiser, and Robin Lycka, each episode features in-depth conversations with leading experts from banking, fintech, regulatory bodies, and investigative journalism.Tune in as we dissect headline news, unpack regulatory trends, and examine the real-world consequences of non-compliance — all through a uniquely compliance-focused lens.The Laundry is proudly produced by Strise.Get in touch at: laundry@strise.ai The views, opinions, and statements expressed by guests of this podcast are solely their own and do not necessarily reflect the views, opinions, or positions of the podcast hosts, The Laundry team, or Strise. Hosted on Acast. See acast.com/privacy for more information.

TRM Talks
From Privacy to Policy: Building the Compliance Layer for DeFi with Nikhil Raghuveera

TRM Talks

Play Episode Listen Later Jul 30, 2025 33:56


This week on TRM Talks, Ari Redbord, Global Head of Policy, TRM Labs, sits down with Nikhil Raghuveera, CEO of Predicate, to talk about the future of compliance in decentralized finance — and why the next wave of policy innovation will be built directly into code.As DeFi matures and regulators sharpen their focus, projects are facing a new challenge: how to meet real-world policy and legal expectations without compromising decentralization. That conversation usually starts with the question — how do you regulate a world without intermediaries? The answer, as Ari and Nikhil explore, is technology.Through its recent partnership with TRM Labs, Predicate enables developers to enforce AML and sanctions safeguards in real time — at the smart contract level — using TRM's risk scoring and attribution. The goal isn't to rebuild the traditional financial system on-chain. It's to build new rails with market integrity, user privacy, and global risk in mind from day one.In this episode, Ari and Nikhil unpack:• Why “policy infrastructure” is critical to supporting both builders and regulators• How TRM and Predicate are powering programmable compliance for stablecoins, privacy protocols, and tokenized assets• What a decentralized transaction prerequisite system actually looks like in practice• The role of zero-knowledge proofs and verifiable risk tooling in preserving user privacy• And how ethical infrastructure can help unlock responsible DeFi growth at scaleThis isn't just a conversation about compliance — it's a blueprint for building trust into decentralized systems.

Oncology Brothers
Challenging Cases with Relapsed/Refractory FLT3+ Acute Myeloid Leukemia (AML)

Oncology Brothers

Play Episode Listen Later Jul 28, 2025 19:01


In this episode of the Oncology Brothers podcast, Drs. Rahul and Rohit Gosain dive into the complexities of relapsed refractory Acute Myeloid Leukemia (AML) with FLT3 mutations. Joined by leukemia specialists Dr. Uma Borate from the Ohio State University and Dr. Naval Daver from the MD Anderson Cancer Center, the discussion focused on real-life cases and the current standard of care for patients with FLT3-positive AML. Key topics included: •⁠  ⁠The importance of retesting for FLT3 mutations at the time of relapse •⁠  ⁠Treatment paradigms for fit vs. unfit patients •⁠  ⁠The role of Gilteritinib and combination therapies in relapsed settings •⁠  ⁠Management of side effects, including cytopenias and differentiation syndrome •⁠  ⁠Insights into the use of hypomethylating agents and the potential of oral therapies Whether you're a healthcare professional or someone interested in the latest advancements in cancer care, this episode provides valuable insights into the management of challenging AML cases. Follow us on social media: •⁠  ⁠X/Twitter: https://twitter.com/oncbrothers •⁠  ⁠Instagram: https://www.instagram.com/oncbrothers •⁠  Website: https://oncbrothers.com/ Don't forget to subscribe for more discussions on the latest in oncology!

AML Conversations
Treasury Postpones AML Rule, Crypto Crime Hits Midyear High, and Russian Universities Teach Sanctions Evasion

AML Conversations

Play Episode Listen Later Jul 25, 2025 22:58


This week, John Byrne and Joe McNamara discuss Treasury's decision to postpone the investment advisor AML rule from 2026 to 2028 and reopen the comment process, drawing criticism from anti-corruption groups who warn it sends the wrong signal during the US's ongoing FATF evaluation. The hosts review Chainalysis's midyear crypto crime report showing $2.17 billion already stolen in 2025, with North Korea's $1.5 billion Bybit hack representing the largest single cryptocurrency theft in history. They also examine the newly signed GENIUS Act on stablecoins and its upcoming regulatory requirements. International developments include Russian universities offering Kremlin-backed master's programs in sanctions evasion and the EU's toughest sanctions package in years, which lowers the Russian oil price cap to $48 per barrel. The episode concludes with updates from the Wolfsburg Group on risk-based approaches and previews upcoming webinars on AI in compliance and fraud prevention.

Oncology Brothers
Treating Acute Myeloid Leukemia in 2025 - Induction, Consolidation, Transplant, Target Therapies

Oncology Brothers

Play Episode Listen Later Jul 24, 2025 25:27


In this episode of The Oncology Brothers, Drs. Rahul and Rohit Gosain are joined by Dr. Anand Patel, a hematologist and Medical Director of Inpatient Leukemia Service at the University of Chicago. Together, they delved into the complexities of acute myeloid leukemia (AML), one of the most aggressive cancers encountered in clinical practice. Episode Highlights: • Understanding the current standard of care for AML, including diagnosis and risk stratification. • The importance of molecular profiling and how it influences treatment decisions. • A detailed discussion on induction chemotherapy options, including the classic 7+3 regimen and CPX351 for therapy-related AML. • Insights into the use of hypomethylating agents combined with venetoclax for patients unfit for intensive chemotherapy. • The role of targeted therapies in both upfront treatment and relapsed/refractory settings. • Key considerations for managing side effects, including cytopenias and infections. Follow us on social media: •⁠  ⁠X/Twitter: https://twitter.com/oncbrothers •⁠  ⁠Instagram: https://www.instagram.com/oncbrothers •⁠  Website: https://oncbrothers.com/ YouTube: https://youtu.be/gbgRbrjHxmQ Join us as we bridge the gap between academic research and community practice, providing valuable insights for healthcare professionals treating AML patients.  Don't forget to like, subscribe, and check out our other episodes for more discussions on challenging cases and treatment algorithms!

CCO Oncology Podcast
A New Revolution in AML Treatment: Can Menin Inhibitors Follow the Path of FLT3 and IDH Inhibitors?

CCO Oncology Podcast

Play Episode Listen Later Jul 24, 2025 22:23


In this episode, Eunice Wang, MD and Eytan Stein, MD explore the latest key clinical updates on menin inhibitors in AML. This episode unpacks evolving treatment strategies and what these developments mean for patient care.Presenters:Eytan M. Stein, MDChief, Leukemia ServiceDirector, Program for Drug Development in LeukemiaAssociate Attending PhysicianLeukemia Service, Department of MedicineMemorial Sloan Kettering Cancer CenterNew York, New YorkEunice S. Wang, MDChief, Leukemia ServiceProfessor of OncologyDepartment of MedicineRoswell Park Comprehensive Cancer CenterBuffalo, New YorkLink to full program: https://bit.ly/4f4an0O

The Laundry
The Soapbox E02: sanctions, fighting financial crime, and AMLA

The Laundry

Play Episode Listen Later Jul 24, 2025 13:47


Welcome to The Soapbox, a summer special from The Laundry. The humble soapbox has been used for free speech and the open sharing of views for over a century!We're channeling that spirit and inviting industry experts to share their hot takes on today's most pressing questions.This week: * Do sanctions make a real impact, or do they just help us feel like we're acting? * What motivates you to keep fighting financial crime?* Is AMLA driving real change, or just more paperwork? Producer: Matthew Dunne-MilesEditor: Dominic DelargyEngineer: Nicholas ThonSubscribe to our newsletter, Fresh Laundry, here.____________________________________The Laundry podcast explores the complex world of financial crime, anti-money laundering (AML), compliance, sanctions, and global financial regulation.Hosted by Marit Rødevand, Fredrik Riiser, and Robin Lycka, each episode features in-depth conversations with leading experts from banking, fintech, regulatory bodies, and investigative journalism.Tune in as we dissect headline news, unpack regulatory trends, and examine the real-world consequences of non-compliance — all through a uniquely compliance-focused lens.The Laundry is proudly produced by Strise.Get in touch at: laundry@strise.ai The views, opinions, and statements expressed by guests of this podcast are solely their own and do not necessarily reflect the views, opinions, or positions of the podcast hosts, The Laundry team, or Strise. Hosted on Acast. See acast.com/privacy for more information.

Banking on Fraudology
$1.2 million related to fraud with Erin O'Loughlin & Brian Svoboda-Kindle

Banking on Fraudology

Play Episode Listen Later Jul 23, 2025 59:34


Banking on Fraudology is part of the Fraudology Podcast Network.In this episode of Banking on Fraudology, host Hailey Windham sits down with Erin O'Loughlin and Brian Svoboda-Kindle from the Association of Certified Financial Crime Specialists (ACFCS) to discuss the critical importance of ongoing education and collaboration in the fight against financial crime. As the financial landscape rapidly evolves, fraud and compliance professionals must stay ahead of emerging threats. The guests highlight how ACFCS is breaking down silos between fraud, AML, cybersecurity and compliance to create a community of experts learning from each other. They dive into the comprehensive benefits of ACFCS membership, including access to cutting-edge training, webinars, virtual events, and networking opportunities. The conversation explores the value of the Certified Financial Crime Specialist (CFCS) credential in providing a broad understanding of financial crime risks beyond just AML or fraud. Listeners will gain insights into how this certification can enhance their skills and career prospects. The episode also previews the upcoming FinCrime Virtual Week in August, promising a wealth of expert sessions on topics ranging from cryptocurrency risks to human trafficking. Whether you're new to financial crime prevention or a seasoned professional, this episode offers valuable guidance on leveling up your expertise and making a bigger impact. Erin O'Loughlin Brian Svoboda-KindleAbout Hailey Windham:As a 2023 CU Rockstar Recipient, Hailey Windham, CFCS (Certified Financial Crimes Specialist) demonstrated unbounding passion for educating her community, organization and credit union membership on scams in the market and best practices to avoid them. She has implemented several programs within her previous organizations that aim at holistically learning about how to prevent and detect fraud targeted at membership and employees. Windham's initiatives to build strong relationships and partnerships throughout the credit union community and industry experts have led to countless success stories. Her applied knowledge of payments system programs combined with her experience in fraud investigations offers practical concepts that are transferable, no matter the organization's size. Connect with Hailey on LinkedIn: https://www.linkedin.com/in/hailey-windham/

a ModelersLife
Episode 267: Dave's Dad - Herman

a ModelersLife

Play Episode Listen Later Jul 21, 2025 78:46


If you live in the Chicago area and a fan of railroading, you will no doubt be well aware of the Indiana Harbor Belt Railroad that's been jointly owned by several railroads over the years. With over 320 miles of track in and around Chicago it's kind of hard to avoid seeing this famous railroad that began in 1896. We here at the ole' AML world headquarters wanted to find out more and it seemed like a natural progression to simply talk to Dave's dad Herman, who worked as a conductor on “the Belt” for over 30 years. Plus he spent time on the “City of New Orleans” and the “Broadway Limited” during a short stint with Amtrak. It's a great podcast and one we're sure you'll enjoy.

The Laundry
The Soapbox E01: one-day regulator, AI takeover, and industry frustrations

The Laundry

Play Episode Listen Later Jul 17, 2025 18:42


Welcome to The Soapbox, a summer special from The Laundry. The humble soapbox has been used for free speech and the open sharing of views for over a century!We're channeling that spirit and inviting industry experts to share their hot takes on today's most pressing questions.This week: * If you were the regulator for a day, what's the one thing you'd change?* What should AI take over — and what should it leave alone?* What's the most frustrating part of your work, and how would you fix it?Producer: Matthew Dunne-MilesEditor: Dominic DelargyEngineer: Nicholas ThonSubscribe to our newsletter, Fresh Laundry, here.____________________________________The Laundry podcast explores the complex world of financial crime, anti-money laundering (AML), compliance, sanctions, and global financial regulation.Hosted by Marit Rødevand, Fredrik Riiser, and Robin Lycka, each episode features in-depth conversations with leading experts from banking, fintech, regulatory bodies, and investigative journalism.Tune in as we dissect headline news, unpack regulatory trends, and examine the real-world consequences of non-compliance — all through a uniquely compliance-focused lens.The Laundry is proudly produced by Strise.Get in touch at: laundry@strise.ai The views, opinions, and statements expressed by guests of this podcast are solely their own and do not necessarily reflect the views, opinions, or positions of the podcast hosts, The Laundry team, or Strise. Hosted on Acast. See acast.com/privacy for more information.

OncLive® On Air
S13 Ep31: IHC Testing Leads to Early Detection of TP43-Mutant AML and MDS: With Jonathan M. Gerber, MD; and Shyam A. Patel, MD, PhD

OncLive® On Air

Play Episode Listen Later Jul 16, 2025 28:45


In today's episode, we had the pleasure of speaking with Jonathan M. Gerber, MD; and Shyam A. Patel, MD, PhD, about a study they conducted investigating the use of immunohistochemistry (IHC) as a biomarker for early TP53 mutation identification in patients with myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). Dr Gerber is a member of the faculty in the Department of Medicine at New York University (NYU) Grossman School of Medicine; as well as the chief clinical officer of the NYU Perlmutter Cancer Center. Dr Patel is an associate professor at the University of Massachusetts Chan Medical School; as well as a hematologist and oncologist at the UMass Memorial Medical Center in Worcester.  In our exclusive interview, Drs Gerber and Patel discussed the evaluation of p53 IHC as a surrogate biomarker for TP53-mutant MDS and AML. They shared how the presence of TP53 mutations in these diseases significantly worsens prognosis, necessitating urgent treatment. They also highlighted how IHC results are available within 48 to 72 hours. Gerber and Patel explained this study's design and patient population, as well as how IHC's inverse correlation with overall survival highlights its potential as an early biomarker, though it has lower sensitivity for certain mutations.

DACOM Digital
MiCA Masters: Risk assessments as a foundation

DACOM Digital

Play Episode Listen Later Jul 16, 2025 40:12


Hercle's Alessio Capriati shares how his team is aligning people, processes, and priorities to meet MiCA head-on. From market abuse to AML, Travel Rule to internal audits, it all starts with knowing your risk and building from there.

iGaming Daily
Ep 559: Why Fresh Capital is Critical for Regulated iGaming, with Cristina Romero

iGaming Daily

Play Episode Listen Later Jul 15, 2025 31:08


In this episode, in collaboration with the International Masters of Gaming Law (IMGL), Cristina Romero of Loyra Abogados, breaks down the complex, often-overlooked, world of fundraising in regulated iGaming markets.With nearly 15 years of experience advising on cross-border gaming finance and acquisitions, she explains why fresh capital is essential for driving innovation, market entry and long-term sustainability in an increasingly capital-intensive industry.From Spain and Sweden to Brazil and beyond, Cristina explores the investment landscape in both mature and emerging iGaming jurisdictions. She categorises the three dominant investor profiles, generalist private equity, gambling-savvy venture firms, and strategic industry players, unpacking what each seeks in a high-risk, high-reward environment.In the final segment, the conversation turns to the evolving relationship between traditional regulated operators and disruptive ‘adjacent' tech firms in Web3, blockchain and AI-powered marketing. Cristina explains how unregulated innovators are setting new benchmarks for speed and agility, often providing vital tools that solve operational pain points for legacy brands.To read more on the topic discussed in today's episode, click on the following link:- https://www.imgl.org/publications/imgl-magazine-volume-3-no-1/raising-capital-in-regulated-gambling-and-betting-markets/Host: Ted MenmuirGuest: Cristina RomeroProducer: Anaya McDonaldEditor: James RossiGaming Daily is also now on TikTok. Make sure to follow us at iGaming Daily Podcast (@igaming_daily_podcast) | TikTok for bite-size clips from your favourite podcast. Finally, remember to check out Optimove at https://hubs.la/Q02gLC5L0 or go to Optimove.com/sbc to get your first month free when buying the industry's leading customer-loyalty service.

Property Apprentice Podcast
Are You a Criminal Just for Selling Your Home? Big Changes to AML Rules in NZ

Property Apprentice Podcast

Play Episode Listen Later Jul 14, 2025 6:03


Send Us A Message! Let us know what you think.In this bonus episode of the Property Apprentice Podcast, host Debbie Roberts breaks down a major change in New Zealand's property regulations that could significantly ease the burden for families using trusts. The New Zealand government has announced key updates to anti-money laundering (AML) rules, aiming to reduce excessive compliance requirements for “low-risk” property transactions involving family trusts. This move is set to simplify the often complex and intrusive checks that everyday Kiwis have faced when selling a home held in a trust. 

WolverHeme Happy Hour
Episode 37: Spilling Drinks over Cytarabine Dosing

WolverHeme Happy Hour

Play Episode Listen Later Jul 11, 2025 58:36


In this episode, Bernie and Anthony talk about some BIG changes in cytarabine dosing in AML consolidation after a recent practice changing article. Will this change your practice? Hunault, et al. NEJM. 2025.https://evidence.nejm.org/doi/full/10.1056/EVIDoa2400326

DACOM Digital
MiCA Masters: The importance of a strong compliance program to scale up

DACOM Digital

Play Episode Listen Later Jul 10, 2025 45:30


Coinhouse's Yoann Briant breaks down what it really takes to scale a crypto firm under MiCA. From company-wide compliance alignment to navigating asset segregation and market abuse challenges, he shares lessons learned from the front lines. We also dive into risk appetite frameworks, France's unique AML requirements, and the rising regulatory tide across Europe. 

The Laundry
E130: What happens when stablecoins go mainstream?

The Laundry

Play Episode Listen Later Jul 10, 2025 34:17


Stablecoins are having a moment – with a bill moving through the U.S. system that could bring the tokens into mainstream regulation.These fiat-backed currencies are presented as the more trustworthy version of crypto, acceptable to the traditional financial system. But hold on – this is still crypto, and that wild west element hasn't been entirely tamed just yet!So what should compliance professionals know?Our expert host, Fredrik Riiser, is joined by Chris Mason, CEO & Co-Founder, Orbital: What happens when stablecoins go mainstream?The pair discuss: the current status of stablecoins, the financial crime challenges they pose, and what mainstream adoption could mean for compliance professionals.Producer: Matthew Dunne-MilesEditor: Dominic DelargyEngineer: Nicholas ThonSubscribe to our newsletter, Fresh Laundry, here.____________________________________The Laundry podcast explores the complex world of financial crime, anti-money laundering (AML), compliance, sanctions, and global financial regulation.Hosted by Marit Rødevand, Fredrik Riiser, and Robin Lycka, each episode features in-depth conversations with leading experts from banking, fintech, regulatory bodies, and investigative journalism.Tune in as we dissect headline news, unpack regulatory trends, and examine the real-world consequences of non-compliance — all through a uniquely compliance-focused lens.The Laundry is proudly produced by Strise.Get in touch at: laundry@strise.aiDisclaimer: The views and information shared here are for general informational purposes only and do not constitute financial, investment, legal, or other professional advice. Authors do not guarantee the accuracy or completeness of the content. Products and services mentioned may not be available in all jurisdictions and are subject to applicable regulations. Listeners and readers should conduct their own due diligence and consult with a qualified advisor before making any financial decisions. Hosted on Acast. See acast.com/privacy for more information.

AML Conversations
Integrating Risk, Fraud, and Technology: Evolving the Risk Assessment Process

AML Conversations

Play Episode Listen Later Jul 8, 2025 18:12


In this episode, Elliot Berman and Jeff Fischer delve into how financial institutions can modernize their risk assessment practices by integrating fraud and AML considerations, responding to regulatory change, and leveraging data more effectively. They discuss the importance of aligning assessments with organizational risk appetite, embracing technology and automation, and adopting a dynamic, proactive approach to risk monitoring. From targeted product assessments to continuous dashboards, this conversation outlines how to streamline complexity while maintaining robust risk intelligence.

AML Conversations
Fentanyl in North America, FinCEN on CIP, OCC, and FATF on VASPs

AML Conversations

Play Episode Listen Later Jul 4, 2025 17:42


In this episode of This Week in AML, Elliot Berman is joined by Joe McNamara to unpack efforts across North America to combat fentanyl trafficking—including Treasury's designation of Mexican financial institutions and Canada's new FinTRAC intelligence unit, FATF's latest update on virtual assets and VASPs, he OCC's report on key risks in the federal banking system, FinCEN's change on TIN collection under the CIP rule, and other issues affecting the financial crime prevention community.

Irish Tech News Audio Articles
Fenergo Creates 300 New Jobs in Ireland as part of €100 million Investment

Irish Tech News Audio Articles

Play Episode Listen Later Jul 4, 2025 10:16


Fenergo has announced 300 new jobs at its global HQ in Dublin. This is part of a €100 million Research, Development & Innovation (RD&I) expansion plan supported by Enterprise Ireland. In addition to the new roles in Ireland, which will double the domestic headcount, Fenergo is creating new jobs across its international markets to meet increasing demand for its AI-powered solutions. A total of 500 new positions will be filled by the company globally within the next three years. With support from Enterprise Ireland, Fenergo has also invested in a new RD&I Centre of Excellence at its Dublin HQ where the new Irish roles will be based, supporting Fenergo's innovation strategy. The new roles will enable Fenergo to further deliver on its mission to support financial institutions in fighting financial crime and creating a safer world. Fenergo will continue to build out its intelligent, AI-powered solutions for client lifecycle management (CLM), anti-money laundering (AML) and Know your Customer (KYC). This suite of solutions forms Fenergo's FinCrime Operating System, which addresses all anti-financial crime events and operations, transforming compliance from a burden into a strategic competitive advantage. Recruitment for the new roles is now underway, with candidates being sought for a wide range of mid-level engineering and R&D positions. Fenergo is also rolling out a graduate programme with the intention to appoint up to 30 university graduates. Interested candidates can find more information about the new jobs and submit applications via: Let's Grow Together | Fenergo. Minister for Enterprise, Tourism and Employment Peter Burke TD welcomed the jobs announcement: "The government and Enterprise Ireland are committed to supporting and accelerating the scaling of ambitious, innovation-led Irish companies. Fenergo is a clear example of ambition in action - a company that has expanded at pace since it first launched in 2009, and one which today represents a standout financial technology solutions provider both globally and domestically. Today's announcement not only represents significant job creation within the Irish market and excellent opportunities for our homegrown talent, but it also reinforces our position as one of the largest and most important tech hubs in Europe. I would like to commend Fenergo on this milestone expansion and their continued investment in Ireland, which I'm confident will underpin further growth for the company while supporting our economy." Marc Murphy, CEO and Founder of Fenergo, said: "I am delighted to announce Fenergo's significant expansion in Ireland with the creation of 300 jobs at our new RD&I Centre of Excellence, which was made possible with the considerable support and investment we have received from Enterprise Ireland. This investment and growth of our Irish operations reflect our confidence in the excellent talent pool we have in this country, and a market where innovative thinking, entrepreneurship and evolving technology will propel Fenergo to new heights. With AI at the core of our RD&I strategy, we are committed to delivering future-proof solutions for financial institutions in Ireland, across Europe, the UK, America, the Middle East and Asia - supporting them during times of intensifying geopolitical tension and regulatory uncertainty. "We are actively recruiting for the new roles already, and I would strongly encourage prospective candidates to consider applying and join our world-class team of change-makers at Fenergo - shaping the future of financial services operations through innovation and AI." Kevin Sherry, Interim CEO, Enterprise Ireland, said: "Ambitious companies like Fenergo embody Enterprise Ireland's mission that Irish-owned, globally focused companies will be the primary driver of our economy. Fenergo, announcing 500 new jobs today, is a great example of an innovative Irish company growing customers, adding RD&I to drive forward AI-powered solutions and creating an impact ...

a ModelersLife
It's Just Thomas

a ModelersLife

Play Episode Listen Later Jun 30, 2025 72:38


It's a return visit to White Rose Hobbies, in York, Pennsylvania. Only this time we're talking with the non-model railroad partner get Thomas who apparently is in charge of ordering paint. We still haven't gotten around to talking about some their great stories from the days of working on the Norfolk Southern but with White Rose agreeing to be the full-time sponsor of the podcast, we'll look forward to it in the future!! However, we here at the old AML nation enjoy hearing about the behind-the-scenes world model railroad retail and everything that goes into it along with it. This is just one of those classic ModelersLife conversations with a returning guest that really has no direction other than to enjoy each other‘s company. It's a great podcast and one we're sure you'll enjoy.

The HemOnc Pulse
Editor's Special Episode: ASCO 2025 Highlights in AML with Dr. Amir Fathi

The HemOnc Pulse

Play Episode Listen Later Jun 29, 2025 15:05


In this Editor's Special of The HemOnc Pulse, Blood Cancers Today Managing Editor, Nichole Tucker speaks with Amir Fathi, MD, of Massachusetts General Hospital, about key updates in AML from ASCO 2025. The discussion centers on a phase 2 study of an all-oral regimen—decitabine and cedazuridine plus venetoclax—for patients with newly diagnosed AML who are unfit for intensive induction. Dr. Fathi discusses the potential for these more convenient therapies to shift treatment into the outpatient setting while maintaining effectiveness. He also shares insights on promising triplet regimens incorporating targeted therapies and highlights the need for new strategies for patients with resistant disease subtypes, such as TP53-mutated or venetoclax-refractory AML. Looking ahead, Dr. Fathi previews anticipated data from menin inhibitor trials and the phase 3 Quantum Wild study. This episode is a must-listen for clinicians and researchers interested in the future of AML care.

AML Conversations
FinCEN 2024 Review, BSA Modernization, Fraud, and FATF Reports

AML Conversations

Play Episode Listen Later Jun 27, 2025 19:37


In this episode of This Week in AML, Elliot Berman is joined by Jennie Jonas to unpack FinCEN's 2024 Year in Review, BSA modernization efforts, and key takeaways from recent FATF reports. They also explore global fraud trends, regulatory shifts in the EU and UK, and the evolving role of digital currencies in financial crime prevention, and other issues affecting the financial crime prevention community.

Fintech Confidential
When Web3 Goes Mainstream, Who Will Be Ready? May 2025 Shows Signs of a Quickly Maturing Market

Fintech Confidential

Play Episode Listen Later Jun 27, 2025 50:25 Transcription Available


Get MoreHost Tedd Huff & Robert Musiala, co-leader of Baker Hostetler's Web3 Digital Assets team, break down May 2025's crypto developments.May 2025 just changed a lot for crypto and Web3. Bitcoin hit $111,970, total crypto assets reached $136 billion, & ETF inflows topped $3.3 billion in a 1 month. The SEC clarified that proof-of-stake mining isn't a security, while the DOJ dropped charges against Ethereum hackers, signaling a major shift in regulatory approach.Ethereum's Petra upgrade increased validator staking limits from 32 to 2,048 ETH, opening doors for massive institutional operations. Yield-bearing stablecoins crossed $9 billion, proving they're no longer experimental tokens. Courts in the US, UK, and EU approved using NFTs for legal service of process, creating new accountability in crypto disputes.The dark side persists: $244 million was stolen in hacks, with $157 million recovered. A Solana report found 98.7% of tokens on pump.fun showed pump-and-dump characteristics. Physical security threats against crypto executives are escalating globally.Institutional investors now represent 50% of trading volume. Circle launched real-time payment APIs, Ripple acquired Hidden Road for $1.25 billion. The convergence of regulatory clarity, institutional adoption, and technical improvements is creating perfect conditions for mainstream crypto adoption.Takeaways1️⃣ Track Validator Staking Changes2️⃣ Research Before Token Investments3️⃣ Explore Programmable Wallet Features4️⃣ Consider Legal NFT Applications5️⃣ Prepare for Staking ComplianceLinks:Guest:Robert A. Musiala Jr. LinkedIn: https://www.linkedin.com/in/robert-a-musiala-jr-esq-cfcs-b6534bb/Company:BakerHostetler: https://www.bakerlaw.com/The Blockchain Monitor: https://www.theblockchainmonitor.com/Fintech Confidential:Podcast: https://fintechconfidential.com/listenNotifications: https://fintechconfidential.com/accessLinkedIn: https://www.linkedin.com/company/fintechconfidentialX: https://x.com/FTconfidentialInstagram: https://www.instagram.com/fintechconfidentialFacebook: https://www.facebook.com/fintechconfidentialSupporters:DFNS - Offering Wallets as a Service with military-grade security and enterprise-grade scalability - https://fintechconfidential.com/dfnsSkyflow - Helping FinTechs build secure experiences without managing customer data directly - https://skyflowsecure.comUnder – Streamlines application and underwriting by digitizing PDF processes for fast digital signatures https://under.io/ftcHawk AI - Providing real-time fraud prevention and AML compliance for FinTechs - https://getHawkai.comAbout:Guest: Robert Musiala has been working in the blockchain and digital assets market since 2012 and has led multiple digital asset investigations, including as the court-appointed receiver over cryptocurrency investment funds used in a major fraud. He advises on various regulatory compliance issues involving digital assets and has drafted/negotiated agreements for a wide range of transactions in the fintech, digital assets, Web3, and NFT markets. He is the inventor of two blockchain patents and co-leader of the Web3 and Digital Assets team at BakerHostetler.Host: Tedd Huff is the founder of Voalyre and Diamond D3. He's spent over 24 years helping fintechs grow by improving payments, user experience, and go-to-market strategies. DD3 Media creates and produces content for Fintech Confidential.

Blood Cancer Talks
Episode 61. Menin Inhibitors in AML with Dr. Eytan Stein

Blood Cancer Talks

Play Episode Listen Later Jun 24, 2025 56:24


In this episode, we took a deep dive intro the landscape of menin inhibitors in AML with Dr. Eytan Stein from MSKCC. Here are the key trials and studies we discussed: ELN 2022 AML Classification https://ashpublications.org/blood/article/140/12/1345/485817/Diagnosis-and-management-of-AML-in-adults-2022Predictors of outcomes in adults with AML and KMT2A rearrangements: https://www.nature.com/articles/s41408-021-00557-6DOT1L inhibitor https://ashpublications.org/blood/article/131/24/2661/37193/The-DOT1L-inhibitor-pinometostat-reduces-H3K79AUGMENT 101: https://ascopubs.org/doi/10.1200/JCO.24.00826Menin inhibition with revumenib for NPM1-mutated relapsed or refractory acute myeloid leukemia: the AUGMENT-101 study: https://ashpublications.org/blood/article/doi/10.1182/blood.2025028357/537139/Menin-inhibition-with-revumenib-for-NPM1-mutatedKOMET-001: https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(24)00386-3/abstractSAVE trial: https://ashpublications.org/blood/article/144/Supplement%201/216/530724/Phase-I-II-Study-of-the-All-Oral-Combination-ofKOMET-007: https://library.ehaweb.org/eha/2025/eha2025-congress/4159213/harry.erba.ziftomenib.combined.with.intensive.induction.chemotherapy.2872B329.in.html?f=menu%3D6%2Abrowseby%3D8%2Asortby%3D2%2Amedia%3D3%2Ace_id%3D2882%2Aot_id%3D31560%2Amarker%3D5843%2Afeatured%3D19595MEN1 mutations: https://www.nature.com/articles/s41586-023-05755-9 

Title Agents Podcast
Cash Buyers, Shell Companies, and FinCEN: The 2025 Compliance Guide for Title Agents

Title Agents Podcast

Play Episode Listen Later Jun 24, 2025 25:16


FinCEN has officially dropped the hammer: a sweeping nationwide rule goes into effect December 1, 2025, requiring title professionals to report the real owners behind all-cash entity purchases of residential real estate. In this episode, Zina and Crosby walk you through the why, what, and how—giving you a clear roadmap to stay compliant and confident. If you've ever handled a deal involving an LLC, trust, or shell company, you need this breakdown before the deadline hits. What you'll learn from this episode Why FinCEN is targeting real estate and why it affects all agent s, not just banks How the GTO pilot evolved into a permanent nationwide mandate Transactions are covered under the new rule Who is responsible for filing and what must be reported Civil and criminal penalties for non-compliance and how to avoid them Practical steps to integrate reporting into your existing title workflows Resources mentioned in this episode  American Land Title Association FinCEn US Department of the Treasury Connect With UsLove what you're hearing? Don't miss an episode! Follow us on our social media channels and stay connected. Explore more on our website: www.alltechnational.com/podcast Stay updated with our newsletter: www.mochoumil.com Follow Mo on LinkedIn: Mo Choumil Stop waiting on underwriter emails or callbacks—TitleGPT.ai gives you instant, reliable answers to your title questions. Whether it's underwriting, compliance, or tricky closings, the information you need is just a click away. No more delays—work smarter, close faster. Try it now at www.TitleGPT.ai. Closing more deals starts with more appointments. At Alltech National Title, our inside sales team works behind the scenes to fill your pipeline, so you can focus on building relationships and closing business. No more cold calling—just real opportunities. Get started at AlltechNationalTitle.com. Extra hands without extra overhead—that's Safi Virtual. Our trained virtual assistants specialize in the title industry, handling admin work, client communication, and data entry so you can stay focused on closing deals. Scale smarter and work faster at SafiVirtual.com.

DACOM Digital
MiCA Masters: The importance of embedding compliance from the start

DACOM Digital

Play Episode Listen Later Jun 23, 2025 54:00


Alexandra Lloyd, Head of AML at YouHodler, joins Delphine Forma on MiCA Masters to explore practical MiCA and DORA compliance, travel rule interoperability, and the real-life process of embedding AML, fraud prevention, and token due diligence into a global crypto platform.

Blood Podcast
Social determinants of health and access to allogeneic hematopoietic cell transplantation, megakaryocyte growth factor receptor-based pretransplant conditioning for ex vivo autologous gene therapy, and novel protein biomarkers for risk stratification in a

Blood Podcast

Play Episode Listen Later Jun 23, 2025 19:38


In this week's episode, we'll learn more about social determinants of health that impact access to allogeneic hematopoietic cell transplantation in patients with acute myeloid leukemia, or AML; use of megakaryocyte growth factor receptor-based stem cell depletion as part of pretransplant conditioning in ex vivo autologous gene therapy; and identification of an eight-protein risk signature as well as a novel single protein biomarker, soluble oncostatin M receptor, for risk stratification in AML.Featured Articles:Social Determinants of Health and Access to Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid LeukemiacMPL-Based Purification and Depletion of Human Hematopoietic Stem Cells: Implications for Pretransplant ConditioningBlood-Based Proteomic Profiling Identifies OSMR as a Novel Biomarker of AML Outcomes

Oyster Stew - A Broth of Financial Services Commentary and Insights
AML in Action: Practical Strategies for Surveillance, Training, and SAR Reporting

Oyster Stew - A Broth of Financial Services Commentary and Insights

Play Episode Listen Later Jun 18, 2025 33:26 Transcription Available


In this episode of the Oyster Stew podcast, Oyster Consulting's Ed Wegener and Bryan Jacobsen break down how firms can implement risk-based monitoring, tailor training for frontline roles, conduct effective investigations, and ensure your firm's Suspicious Activity Report (SAR) filings are what regulators require.Key Takeaways What regulators expect from your AML compliance programRisk-based surveillance: Going beyond cookie-cutter monitoringHow to tailor red flag training by employee roleInvestigating suspicious activity: When to file a SAR, how to do it rightLeveraging third-party vendors for transaction surveillance and case managementCommon mistakes firms make—and how to avoid themOyster Consulting has the expertise, experience and licensed professionals you need, all under one roof. Follow us on LinkedIn to take advantage of our industry insights or subscribe to our monthly newsletter. Does your firm need help now? Contact us today!

The Broker Link
Annuity Awareness Month: Securing a Lifetime of Income

The Broker Link

Play Episode Listen Later Jun 17, 2025 11:02


In this episode, Cheryl Chapman, Annuities Specialist with 19 years of experience, joins Sherry Kelson, Director of the Life Team at The Brokerage Inc., to break down what agents need to know about annuities. Cheryl walks through the key requirements for selling annuities, including: A life and health license State-specific certifications Anti-money laundering (AML) training Errors & omissions (E&O) coverage Product-specific training She explains the main types of annuities—fixed, indexed, and single premium income annuities (SPIAs)—and shares how each can serve clients' long-term goals like retirement, college funding, or guaranteed income. With current interest rates around 5.3%, annuities are becoming an attractive, low-risk option offering tax-deferred growth and portfolio diversification. Cheryl also notes that annuities typically issue within a week, and agents can reach out to her directly for guidance and support. You can reach Cheryl through The Brokerage Inc. website. Learn more about partnering with The Brokerage Inc. by visiting our website, www.thebrokerageinc.com. Remember to like, share, and subscribe to our show!  New episodes are available every Tuesday. Join our Community! LinkedIn: https://www.linkedin.com/company/the-brokerage-inc-/   Facebook:  https://www.facebook.com/thebrokerageinc/  Instagram:  https://www.instagram.com/thebrokerageinc/  YouTube:  https://www.youtube.com/@TheBrokerageIncTexas  Website:  https://thebrokerageinc.com/ 

Stephan Livera Podcast
MEV, Censorship & Why We Need To Save Our Wallets with Matt Corallo | SLP667

Stephan Livera Podcast

Play Episode Listen Later Jun 16, 2025 102:52


Stephan & Matt discuss the ‘Save Our Wallets' campaign, which aims to protect non-custodial wallets from regulatory challenges posed by the U.S. government. He highlights the legal risks developers face due to broad interpretations of regulations and the potential consequences of future administrations. The importance of advocacy for legislative change, user engagement, and improving user experience in Bitcoin transactions are emphasized. Additionally, the conversation touches on the implications of AML and FATF regulations, the evolution of wallet technologies, and the need for research into Miner Extractable Value (MEV) in Bitcoin. They also discuss various aspects of Bitcoin and Ethereum, focusing on the implications of MEV (Miner Extractable Value), the risks of mining centralization, and the importance of investing in solutions rather than relying on consensus changes. They explore the challenges posed by private order flow, the philosophical differences in Bitcoin development, and the future of Bitcoin Core and node adoption.Takeaways

Stephan Livera Podcast
Your Financial Data Can Be Weaponized Against You with Lyudmyla Kozlovska | SLP665

Stephan Livera Podcast

Play Episode Listen Later Jun 13, 2025 36:27


Lyudmyla Kozlovska, President, Open Dialogue Foundation discusses the intersection of Bitcoin, human rights, and the weaponization of financial regulations. She highlights the dangers of transnational financial repression, where authoritarian regimes exploit financial action task force (FATF) and anti-money laundering (AML) regulations to target individuals and organizations. The discussion emphasizes the need for privacy protection, legislative change, and active advocacy to safeguard civil liberties in the face of increasing surveillance and repression.Takeaways

The Oncology Nursing Podcast
Episode 367: Pharmacology 101: PARP Inhibitors

The Oncology Nursing Podcast

Play Episode Listen Later Jun 13, 2025 28:25


Episode 367: Pharmacology 101: PARP Inhibitors “We know that in cells that are proliferating very quickly, including cancer cells, single-strand DNA breaks are very common. When that happens, these breaks are often repaired by the PARP enzyme, and the cells can continue their replication process. If we block PARP, that repair cannot happen. So in blocking that, these single-strand breaks then lead to double-strand breaks, which ultimately is leading to cell apoptosis,” Danielle Roman, PharmD, BCOP, manager of clinical pharmacy services at the Allegheny Health Network Cancer Institute in Pittsburgh, PA, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about the PARP inhibitor drug class. Music Credit: “Fireflies and Stardust” by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.5 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by June 13, 2026. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge related to the use of PARP inhibitors in cancer care. Episode Notes  Complete this evaluation for free NCPD.  ONS Podcast™ episodes: Pharmacology 101 series Episode 330: Stay Up to Date on Safe Handling of Hazardous Drugs Episode 232: Managing Fatigue During PARP Inhibitor Maintenance Therapy Episode 227: Biomarker Testing, PARP Inhibitors, and Oral Adherence During Ovarian Cancer Maintenance Therapy ONS Voice articles: PARP Inhibitors and Ovarian Cancer Genomics May Trick PARP Inhibitors to Treat More Cancers Oncology Drug Reference Sheet: Niraparib ONS books: Chemotherapy and Immunotherapy Guidelines and Recommendations for Practice (second edition) Clinical Guide to Antineoplastic Therapy: A Chemotherapy Handbook (fourth edition) Safe Handling of Hazardous Drugs (fourth edition) ONS courses: Safe Handling Basics Clinical Journal of Oncology Nursing articles: PARP Inhibition: Genomics-Informed Care for Patients With Malignancies Driven by BRCA1/BRCA2 Pathogenic Variants Talazoparib Plus Enzalutamide in Patients With HRR-Deficient mCRPC: Practical Implementation Steps for Oncology Nurses and Advanced Practice Providers Oncology Nursing Forum article: Familiarity and Perceptions of Ovarian Cancer Biomarker Testing and Targeted Therapy: A Survey of Oncology Nurses in the United States Oral Anticancer Medication Care Compass: Resources for Interprofessional Navigation ONS Biomarker Database ONS Oral Anticancer Medication Learning Library ONS Oral Anticancer Medication Toolkit Oral Chemotherapy Education Sheets To discuss the information in this episode with other oncology nurses, visit the ONS Communities. To find resources for creating an ONS Podcast Club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode “The big toxicities here to watch for are primarily hematologic toxicities. It is one of those targeted therapies that does affect blood cell counts. So I'd say the blood cell count that is most commonly affected here is the hemoglobin. So, anemia very frequent complication that we see, probably a little bit more with olaparib compared with other drugs, but we see it as a class side effect. And we can also see neutropenia and thrombocytopenia with these agents, probably a little bit more with niraparib versus the others, but again, you can see it across all of these drugs.” TS 8:16 “We mentioned that rare risk of MDS and AML. This isn't a particularly scary thing if you talk to patients about it. Because of the rarity that we see this, it isn't something that we need to overemphasize, but I think careful monitoring of blood counts in is stressing the importance of that and early intervention here is very important.” TS 16:55 “This is a collaborative effort. And because of the home administration here, these patients do need to be followed very closely. So we are not laying eyes on them usually with the frequency that we do when we have patients actually coming into our infusion centers for treatments—so making sure that there is a plan for regular follow-up with these patients to ensure that they're getting that lab work done, that that's being looked at closely, that we're adjusting the dose if we need to based on that lab work, that we are managing the patient's fatigue. Again, that potentially dose reductions may be needed if patients are having that extreme fatigue.” TS 19:34 “I think one of those [misconceptions] could be that they're only effective in patients that have that BRCA1/2 mutation. And again, remember here that there is some data in particular disease states that we can use them and that they work in the absence of those mutations.” TS 25:12

Artificial Intelligence in Industry with Daniel Faggella
Driving AI in Fraud and AML Compliance for Financial Services - with Nick Lewis of Standard Chartered Bank

Artificial Intelligence in Industry with Daniel Faggella

Play Episode Listen Later Jun 10, 2025 20:58


In this second of a two-part series, Nick Lewis, Managing Director for the High Risk Client Unit at Standard Chartered Bank, returns to the AI in Business podcast to unpack the ongoing transformation of anti-financial crime efforts in an increasingly digitized world. In this episode, Nick and Emerj Editorial Director Matthew DeMello examine the persistent tension between rule-based alert systems and the nuanced, judgment-driven work of human investigators in financial crime prevention. Nick highlights how current AML workflows still rely heavily on deterministic systems that struggle to distinguish legitimate anomalies from criminal behavior—and why AI solutions must be deployed carefully to avoid removing critical human oversight. Want to share your AI adoption story with executive peers? Click emerj.com/expert2 for more information and to be a potential future guest on the ‘AI in Business' podcast! If you've enjoyed or benefited from some of the insights of this episode, consider leaving us a five-star review on Apple Podcasts, and let us know what you learned, found helpful, or liked most about this show!

X22 Report
Trump Sends Message, Shall We Play A Game, It Had To Be This Way, Old Guard Threatened – Ep. 3634

X22 Report

Play Episode Listen Later May 4, 2025 97:50


Watch The X22 Report On Video No videos found Click On Picture To See Larger Picture The [DS]/[CB] green agenda is falling apart, everything they said the opposite is happening. Another solar company goes belly up. China is trying to skirt the tariffs, this will fail. The tariffs are working, companies are moving back. Trump messages that we are in a transition and soon the people will see the gold. The [DS] is going down the path that trump sent. They are now exposing their infiltration and people can now see the entrenched enemy. Trump and the patriots are playing the game and it had to be this way to show the people the criminal syndicate. Trump has removed the three sides of the triangle and now the old guard is threatened.   (function(w,d,s,i){w.ldAdInit=w.ldAdInit||[];w.ldAdInit.push({slot:13499335648425062,size:[0, 0],id:"ld-7164-1323"});if(!d.getElementById(i)){var j=d.createElement(s),p=d.getElementsByTagName(s)[0];j.async=true;j.src="//cdn2.customads.co/_js/ajs.js";j.id=i;p.parentNode.insertBefore(j,p);}})(window,document,"script","ld-ajs"); Economy https://twitter.com/KanekoaTheGreat/status/1918915519245381969  approximately 108 gigatons per year. https://twitter.com/TheCalvinCooli1/status/1918390219939934430 https://twitter.com/Rickster_75/status/1918331034493698275 TAKE A LISTEN   European Union To Ban Anonymous Crypto & Privacy Tokens By 2027   The European Union is set to impose sweeping Anti-Money Laundering (AML) rules that will ban privacy-preserving tokens and anonymous cryptocurrency accounts from 2027. Under the new Anti-Money Laundering Regulation (AMLR), credit institutions, financial institutions and crypto asset service providers (CASPs) will be prohibited from maintaining anonymous accounts or handling privacy-preserving cryptocurrencies, such as Monero and Zcash. “Article 79 of the AMLR establishes strict prohibitions on anonymous accounts [...]. Credit institutions, financial institutions, and crypto-asset service providers are prohibited from maintaining anonymous accounts,” according to the AML Handbook, published by European Crypto Initiative (EUCI).   The regulation is part of a broader AML framework that includes bank and payment accounts, passbooks and safe-deposit boxes, “crypto-asset accounts allowing anonymisation of transactions,” and “accounts using anonymity-enhancing coins.” Source: zerohedge.com https://twitter.com/KobeissiLetter/status/1919013699873821077   see a CEO with such a historic run again? https://twitter.com/KanekoaTheGreat/status/1918490939531657501  in homelessness. And they still called it "the best economy ever." China Reroutes Targeted Goods to Friendly North American Partner to Avoid Tariffs As if on cue, a short article from the Chamber of Shipping notes that cargo from China is being rerouted to avoid tariffs. The destination of the cargo is,   CANADA! USCoS –  experts caution that prolonged storage costs—estimated at $1,750 per container per week—and limited warehouse capacity could force sellers to offload discounted goods into the Canadian market, potentially disrupting domestic manufacturing. Others warn the strategy is risky and unsustainable, especially if the trade conflict drags into next year's U.S.-Mexico-Canada Agreement negotiations. (link) This will not end well…. … For Canada. Source: theconservativetreehouse.com When Americans' clothes were made in America U.S. Trade Representative posts shocking chart showing percentage of onshore manufacturing The post reads: "Reviving apparel production in America is not a pipe dream. It was not that long ago we were manufacturing 56% of U.S. apparel in America. 'Made in America' is an economic and national security priority of this administration." "@POTUS' trade actions are ushering in a reshoring renaissance as companies pledge billions of dollars to e...