Podcasts about Precision medicine

In 1987, Mary P. Lovato, a member of Kewa Pueblo in New Mexico, was diagnosed with acute leukemia. To receive a bone marrow transplant, she had to travel more than 800 miles from home because specialized cancer care was unavailable through the Indian Health Service. When she returned, she discovered another obstacle: many in her community feared cancer so deeply that they avoided speaking about it altogether.This episode examines how cancer survivorship exposed profound inequities in the American healthcare system. Long before health equity became a national priority, advocates from underserved communities were confronting disparities rooted in geography, poverty, racism, language, underfunded healthcare systems, and historical mistrust of medical institutions. Their work demonstrated that scientific advances alone cannot improve survival if patients cannot reach, afford, or trust the care available to them.The story follows pioneers including Mary P. Lovato, who built the first national Native-led cancer support and education program for Indigenous communities, and Maimah Karmo, founder of the Tigerlily Foundation, whose breast cancer diagnosis inspired a movement to improve early detection, clinical trial participation, and representation for Black women. Their advocacy challenged longstanding barriers to culturally competent care while highlighting persistent inequities in access to screening, fertility preservation, navigation, and innovative treatments.The episode also explores why diversity in clinical research matters. For decades, many cancer clinical trials disproportionately enrolled White patients, limiting both access to promising therapies and the scientific understanding of how treatments perform across different populations. Researchers, patient advocates, and community leaders responded by redesigning outreach, improving patient navigation, reducing logistical barriers, and insisting that affected communities help shape the research itself.Cancer survivorship cannot be measured solely by scientific breakthroughs. It also depends on whether every patient has a meaningful opportunity to benefit from them. The pursuit of health equity remains one of the defining challenges and enduring responsibilities of modern oncology.RELATED LINKSNational Cancer Institute | Cancer Health Disparities⁠Indian Health Service⁠Tigerlily Foundation⁠National Cancer Institute | Cancer Clinical Trials⁠American Indian Cancer Foundation⁠Abramson Cancer Center | University of Pennsylvania⁠FEEDBACKLike this episode? Rate and review The Cancer Mavericks: A History of Survivorship on your favorite podcast platform. For more information, visit CancerMavericks.com. Please send any questions to podcasts@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode, William Morice II, MD, PhD, President and Chief Executive Officer, Mayo Clinic Laboratories, discusses the evolving role of diagnostics, AI and precision medicine in improving patient care. He also shares Mayo Clinic Laboratories' growth priorities, the changing expectations of patients and the challenges of advancing innovation amid reimbursement pressures.

June 24th, 2006. Historic Fort York, Toronto. Twenty-two songs, and buried at number fourteen is a track The Tragically Hip only ever played nine times.That is the version we spin. Same night they pulled '38 Years Old' out of the vault for the first time since July of 1995. Nine plays for 'No Threat', per Hipbase and setlist.fm, and one of those nine got audited live on this stream. There was an entry claiming November 15th, 1991. Andrew went after it, Steve pulled the tape down to check, and the correction went in while the mics were still hot.'No Threat' opens "Yer Favourites", the November 2005 double disc where fans voted on every track except the two nobody had heard yet. This one, and 'The New Maybe' closing disc two. Adam Kasper made both, the same man who made "In Between Evolution" the year before. Track one is the brand new song. Track two is 'Grace, Too'. Kevin has a word for that sequencing decision, and the word is bold.It landed at 85 on the TTHTop40 Countdown, between 'Daredevil' and 'Sherpa'. Then the poll came back from the Facebook group with a stack of loves, which was nobody's prediction at this table, plus eight percent who came right out and said they dislike it. Steve did not vote. Steve tells us where he would have landed, and it opens something bigger than the song: what do you do with a band you love and songs you don't? He has a list. He is not sorry about the list.Then there is the guitar. Jeff from Vaughan puts it in the chat first, that it is the guitar that doesn't work here, and Kevin has been circling the same thing all week. A chord that goes somewhere your ear refuses to follow. He can tell you which side of the mix it comes from and which of the two of them is playing it.WHAT ELSE IS IN HERE• Yelly Gord. Andrew's name for the thing that starts here and does not stop, straight through 'Yer Not the Ocean' and into a version of 'Blow at High Dough' that is barely a word any more. Where it came from, and which album this song belonged on instead.• Kevin catches the flip. First person the whole way through, and then for one line it isn't, and there is a woman in the room.• The last thing Gord says in the song. Nobody here can explain it. Three theories, no verdict, and one line jD reads out that stops everybody cold: you die to your fans one window at a time.• Andrew went hunting the origin story. Nine or ten full shows from 1996, chasing a rant that is supposed to be the seed of this song. He did not find it. He found something else about peacekeeping that he cannot now unhear.• The Hip headlined the first two concerts ever held at the Air Canada Centre. Steve knows who opened, and who played the third night.• The anniversary weekend. jD in Kingston for Springer Market Square, murals and painted guitars all over a town that does not normally do it up. Steve stretched it over three days in Toronto and got a west end blackout two songs into the last show. Kevin was in Ireland.• The live record, and the two songs on it that are not live. Andrew has a fix.• End of summer picks. Steve's 'The Dire Wolf' and a whole summer in Kingston in 2002. Andrew's '11th Fret', a hangover song and he means that kindly. Kevin's 'Three Pistols', Tom Thomson and Algonquin Park. Steve's first answer was not one of theirs at all, and he owns it on air.Next week the wheel lands on 'Putting Down' from "Music @ Work". Which the band played at Fort York that same June night in 2006, four songs before this one. So there's that.THE PANEL• Kevin from Sarnia. First time at the table. He was buying every one of these records the week it came out and cannot remember buying this one, which tells you something. Plays in a cover band called 402 West, named for the highway between London and Sarnia.• Andrew from Winnipeg. Back again, and the closest thing this show has to a research department. Plays bass in Crooked Ice, whose record is "Dark Stars", and he cut the video too. His radio show and podcast is Soup Full of Radio.• Steve from Toronto. Fourth time on a jD show inside a month, which he points out himself. At Fort York in 2006, in the building in Kingston in 2016. He rides for the Tragically Clipped, a Princess Margaret Cancer Foundation team that began as an act of spite between two friends and has raised over $200,000 since. What happened to one of his riders at a rest stop is worth the wait.GEDFEST TORONTO - SATURDAY, OCTOBER 17The Horseshoe Tavern, with Grace, 2. Every dollar goes to Campfire Circle and the Murphy Family Fund in Precision Medicine in Pancreatic Cancer. Tickets through facebook.com/GEDfestYYZ.YER LETTEROnce a month, the whole network in one email. Where the shows are headed, what got made, and what did not fit anywhere else. Free. subscribe.tthpods.comTHE TIP JARIf the shows are worth something to you, buymeacoffee.com/tthtop40.FIND USHome: home.tthpods.comEmail: jd@tthpods.comFacebook community: community.tthpods.comInstagram: @tthpodsYouTube: youtube.com/@tthpodsYer Letter: subscribe.tthpods.comMORE THE TRAGICALLY HIP ON SHUFFLE LIVE STREAM'Tiger The Lion': https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/718fe20e-83d6-4c69-86eb-cc2b4af02834'Emperor Penguin': https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/a2f229b2-b5fc-41e4-8d78-632080d31a3b'Pigeon Camera': https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/49a9167c-6f8d-4641-8306-959189b38ec8Live performance counts, dates, and the Fort York set list come from Hipbase and setlist.fm, as cited on the stream. Production credits from the "Yer Favourites" liner notes.#TheTragicallyHip #YerFavourites #TTHOnShuffle #GordDownie #TheHip #TTHPodsSupport this podcast at — https://redcircle.com/tthtop40/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

In 2000, Katie Couric underwent a live colonoscopy on national television following the death of her husband, Jay Monahan, from colorectal cancer at age 42. The broadcast demystified a procedure many Americans feared, led to an estimated 20% increase in colonoscopy screenings, and became one of the clearest examples of how public storytelling can change healthcare behavior.This episode examines how celebrities, journalists, filmmakers, and entertainers helped reshape the public conversation about cancer during a period when survivorship was becoming increasingly visible. As breakthroughs in targeted therapies, immunotherapy, and early detection allowed more people to live beyond cancer, public figures used their platforms to encourage screening, reduce stigma, and accelerate research. Their influence extended far beyond awareness campaigns, helping transform cancer from a private diagnosis into a national public health conversation.Central to this story is Laura Ziskin, the Hollywood producer behind Pretty Woman and the Spider-Man films, whose metastatic breast cancer diagnosis inspired the creation of Stand Up To Cancer. Working alongside Couric and leaders from entertainment, journalism, and biomedical research, Ziskin championed a new funding model that required multidisciplinary scientific collaboration, helping accelerate discoveries that contributed to multiple FDA-approved cancer therapies. The episode also highlights the advocacy of actor Patrick Dempsey, whose family's experience with ovarian cancer led to the creation of the Dempsey Center, expanding support for patients and caregivers beyond medical treatment.The story also asks what celebrity advocacy often leaves unsaid. Financial toxicity, caregiver burden, chronic pain, mental health, and the long-term effects of treatment rarely receive the same attention as dramatic diagnoses or breakthrough cures. As cancer survivorship continues to evolve, the greatest challenge may not be convincing people to care about cancer, but helping them understand what it truly means to live with and beyond it.RELATED LINKSStand Up To Cancer⁠Katie Couric Media⁠Dempsey Center⁠American Association for Cancer Research⁠National Cancer Institute⁠Dana-Farber Cancer Institute | Adult Survivorship Program⁠FEEDBACKLike this episode? Rate and review The Cancer Mavericks: A History of Survivorship on your favorite podcast platform. For more information, visit CancerMavericks.com. Please send any questions to podcasts@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Wellness trends move fast, yet volume two of The Next Frontier Files proves some predictions age well. Revisiting year two of the show, host Jenn Trepeck tracks the guests who forecasted metabolic health, gut health, and body positivity long before they became mainstream conversations, and shows how precision medicine and permission became the defining threads of an entire year.Jenn Trepeck brings listeners of Salad with a Side of Fries a look back at the guest predictions that shaped the year two, August 2020 - August 2021, grading them against what really happened since.What You Will Learn in This Episode:✅ How telehealth and virtual training went from pandemic workaround to a permanent part of everyday healthcare✅ Why metabolic health and gut health became two of the most repeated topics in wellness over the following years✅ What guests predicted about wearable technology, gene editing, and the future of human biology✅ How body positivity and permission-based wellness reshaped the conversation around health and self-imageThe Salad With a Side of Fries podcast, hosted by Jenn Trepeck, explores real-life wellness and weight-loss topics, debunking myths, misinformation, and flawed science surrounding nutrition and the food industry. Let's dive into real-life wellness and weight loss, including drinking, eating out, and skipping the grocery store.TIMESTAMPS:00:00 Year two overview explains how telehealth shifted from workaround to permanent wellness trends infrastructure04:42 Chad Levy discusses virtual training, and Amy Marshall shares her perspective on Telehealth and Zoom technology06:55 Chris Burres introduces longevity as a frontier, and Natasa Billeci mentions AI and propels the precision medicine conversation08:49 Toxin exposure and cellular absorption enter the conversation through Tim James' product launch12:01 Corey Phelps highlights her views on meditation and breathwork12:58 Dr. Casey Means discusses metabolic health tools and using technology to return to basics15:53 Gut health gets its first mention by Mike Millner, predicting it is only 2% understood16:53 Dr. Anthony Balduzzi predicts gene therapy, CRISPR, and implantable technology merging with human biology18:25 Catharine Arnston embraces preventative medicine19:13 Sarah Nilsen expounds about CBD and cannabinoid research20:12 Jay Shifman comments on BMI and asks why is it still being used21:17 Sarah Malouf and Farah M. Green raise body positivity and the pressure to redefine beauty standards23:20 Jenn closes by tying the year's predictions together under precision and permissionKEY TAKEAWAYS:

In 2006, a landmark report titled Closing the Gap: Research and Care Imperatives for Adolescents and Young Adults with Cancer confirmed what young survivors had been saying for years. While survival rates for children and older adults had steadily improved, adolescents and young adults had experienced decades of stalled progress. They had become cancer's lost generation.This episode explores how young adult survivors transformed their shared isolation into one of the most influential grassroots movements in cancer advocacy. Diagnosed during the years typically devoted to education, careers, relationships, and starting families, patients between the ages of 15 and 39 confronted challenges that extended far beyond treatment. Fertility preservation, sexual health, employment, financial toxicity, insurance, and long-term quality of life were rarely discussed in oncology clinics, leaving many to navigate survivorship alone.The episode follows advocates including Tamika Felder, Lindsay Avner, Heidi Adams, Doug Ulman, and Dr. Archie Bleyer, whose research and advocacy fundamentally changed how medicine understands adolescent and young adult cancer. Through organizations including Planet Cancer, Fertile Hope, the Lance Armstrong Foundation, and later Stupid Cancer, survivors built online communities, educational resources, conferences, and national partnerships that challenged long-standing assumptions about cancer care. Their work helped establish fertility preservation as a standard discussion before treatment, expanded research dedicated to adolescent and young adult oncology, and elevated quality of life as a critical clinical outcome alongside survival.The movement also demonstrated the power of lived experience to reshape medicine. Survivors became researchers, educators, nonprofit founders, and policy advocates, insisting that cancer care account not only for years of life saved, but for the lives patients hoped to build afterward.What began as a search for peers evolved into a national movement that permanently transformed adolescent and young adult oncology. Today, dedicated research programs, clinical fellowships, survivorship resources, and patient advocacy organizations continue to build on the foundation these young cancer mavericks created.RELATED LINKSNational Cancer Institute | Adolescent and Young Adult (AYA) Cancer Program⁠Closing the Gap: Research and Care Imperatives for Adolescents and Young Adults with Cancer⁠American Society of Clinical Oncology | Fertility Preservation Guidelines⁠Stupid Cancer⁠Livestrong Foundation⁠Journal of Adolescent and Young Adult Oncology⁠FEEDBACKLike this episode? Rate and review The Cancer Mavericks: A History of Survivorship on your favorite podcast platform. For more information, visit CancerMavericks.com. Please send any questions to podcasts@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if healthcare wasn't just about treating disease—but helping people become the strongest, healthiest, most vibrant version of themselves?In this fascinating and forward-thinking episode, I sit down with John Goldman, Human Performance Advocate, visionary in Precision Medicine, and Founder & CEO of Rebel Health Alliance.John shares why he rebelled against the traditional healthcare system and created a revolutionary parallel healthcare model focused on prevention, optimization, and coordinated personalized care. Instead of waiting until people get sick, Rebel Health Alliance is designed to help individuals proactively improve their health, energy, resilience, and quality of life through data-driven, highly personalized support.We explore how modern lifestyles are quietly making many people sick and overweight—and why small daily habits, consistency, structure, and proactive health choices can dramatically transform our future.John explains how Rebel Health Alliance combines cutting-edge diagnostic technology with a carefully curated team of experts—including doctors, strength coaches, dieticians, and epigenetic counselors—all coordinated around the individual. Through virtual care, members gain convenient access to personalized support through text, voice, and video while keeping costs more affordable than traditional healthcare models.One of the most inspiring moments in the conversation is when John shares his personal goal of becoming a “bad ass grandpa”—living a long, healthy, energetic life filled with vitality and purpose. His mission is not simply helping people avoid illness, but helping them truly thrive.We also discuss:Why prevention matters more than waiting for diseaseThe limitations of insurance-based healthcareThe importance of discipline and daily habitsRebuilding energy, focus, and resiliencePrecision medicine and personalized careThe role of accountability and support in long-term transformationCost-sharing options for unexpected medical emergenciesWhy health optimization should feel personal and human—not transactionalJohn's passion for empowering people to take ownership of their health is contagious, and this episode offers hope for anyone searching for a more proactive and personalized approach to wellness.You can learn more about John and Rebel Health Alliance at: Rebel Health Alliance WebsiteConnect with John on social media:Twitter/X @JohnGoldmanInstagramLinkedInIf you enjoyed this episode, please share it with someone who is ready to take a proactive approach to their health and future.Listen, Share, and SupportIf this episode resonated with you, please share it with someone who may need hope today.Be sure to subscribe, leave a rating and review, and help us spread more healing and inspiration to the world.Free Resource for HealingIf you're ready to release stress, calm your mind, and begin healing from within, visit:

June 16th, 2000. The first of only 89 times The Tragically Hip ever played 'Tiger The Lion' live, and the last one is a long way off from there.Eighty-nine, per Hipbase and setlist.fm. That's the whole run, first to last, June 2000 to a night in November 2009. Fifteen of those as an opener, which makes sense to everybody at the table. Fifteen as an encore, which makes sense to nobody. It never went out as a single. The record it sits second on went two times platinum in Canada and took home the Juno, and it's the second of the two Steve Berlin made with the boys. 'Tiger The Lion' landed at number 65 on the TTHTop40 Countdown and not one person in this room is at peace with that.Then there's the poll. Just over half the Facebook group came back with love it, which the panel did not see coming, and close to eight in ten landed at like it or better. For a track this strange, sitting where it sits, that's a number worth chewing on. Somebody in the comments wanted an option between love it and like it. Jeff has a fix for that, and it's better than extra medium.Duxoop from Toledo dropped a question in the chat that stopped the table cold. What is that opening noise? Jeff had already gone looking earlier in the week, so we get the answer live: what the sound actually is, who made it, and the instrument buried underneath it that most of the congregation has never once picked out. Twenty-six years of listening and there it is, right in front of everybody the whole time.We spin the MuchMusic Intimate & Interactive version from that same summer, Chris Brown and Kate Fenner on stage with them, and then Jeff comes back with something none of us caught. Gord is reciting under Rob's outro. Not scatting. Reciting. From a poem, by a Canadian poet Gord loved enough to record in full for a tribute record years later. And the hotel that poem is named for is a ten minute walk from where Jeff grew up.WHAT ELSE IS IN HERE• John fucking Cage. Greg pulls the passage Gord was reading and puts it in a bigger frame, and it turns out to be about a whole lot more than music. Jeff, meanwhile, has listened to some John Cage and has thoughts about it that are not kind, and he says them anyway.• A song with no chorus. Not a bridge in the middle either, just a break. So how does it hook anybody? Dave takes a run at that one, and at what Rob does on the outro instead of what any other guitar player would have done with all that room.• Greg's theory that the catalogue splits into four groups, that this is where the art rock properly starts, and that this cut sits in the top five heaviest songs the band ever recorded. Bombs dropping. His words.• The sequencing. 'My Music At Work' into 'Tiger The Lion' into 'Lake Fever'. Dave would have moved it. Greg would not have moved a thing.• Where the lyrics turn. Dave on the shift that starts around this record and how much harder Gord makes you work from here on in, and Greg on the mouth shapes and the dancing and writing words that sound right before they mean anything.• First listens. A leaked MP3 that took seven hours to download. A boombox on a deck in Tacoma running the record two days straight. A Calgary apartment full of diehards filing this one under wait, what.Next week the wheel lands on 'No Threat', one of the two new tracks tucked onto "Yer Favourites". Brand new panel, brand new song.THE PANEL• Greg from Tacoma. Met the boys back around 'New Orleans Is Sinking', has seven to ten copies of every CD and gave most of them away. He makes music with AI under Hadees Market Music, spelled H-A-D-E-E-S, after his grandparents Hazel and Ira D.• Jeff from Belleville. Third time in the chair. Belleville sits on the Bay of Quinte, which is exactly why the last ten minutes of this one belong to him.• Dave from Halifax. First time at the table, and a musician, which shows the second the outro starts.GEDFEST TORONTO - SATURDAY, OCTOBER 17The Horseshoe Tavern, with Grace, 2. Every dollar goes to Campfire Circle and the Murphy Family Fund in Precision Medicine in Pancreatic Cancer. Tickets through facebook.com/GEDfestYYZ.THE TIP JARGreg asked for this link on mic, so here it is. If the shows are worth something to you, buymeacoffee.com/tthtop40.FIND USHome: home.tthpods.comEmail: jd@tthpods.comFacebook community: community.tthpods.comInstagram: @tthpodsYouTube: youtube.com/@tthpodsYer Letter: subscribe.tthpods.comMORE THE TRAGICALLY HIP ON SHUFFLE LIVE STREAM'Emperor Penguin': https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/a2f229b2-b5fc-41e4-8d78-632080d31a3b'Pigeon Camera': https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/49a9167c-6f8d-4641-8306-959189b38ec8'Gus: The Polar Bear From Central Park': https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/68d2991b-9074-43ef-bd71-aa832c59a787Live performance counts, dates, and chart details come from Hipbase and setlist.fm, as cited on the stream. Album details from the "Music @ Work" credits.#TheTragicallyHip #MusicAtWork #TTHOnShuffle #GordDownie #TheHip #TTHPodsSupport this podcast at — https://redcircle.com/tthtop40/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Hey, it's jD here. August 20th, 2026. Bath, Ontario. A stone coach house west of Kingston that the band turned into a recording room, where "Phantom Power", "Music @ Work", "We Are The Same", and "Man Machine Poem" were all made. Ten years to the day since the last show. This is the last one. Yer Hipstories: Reflections From The Final Tour ran the length of the Man Machine Poem Tour, city by city, Victoria east to Kingston, and it ends here, in the room where the last record was made. Three fans at the table, and not one of them tells August 20th the same way. One was on the floor. One was in the square with 25,000 people. One was on his couch in Brockville with a bottle of wine and a good reason.

Have you heard about the radioactive wolves in Chernobyl? Or the latest gene-editing tech that's curing rare diseases? Or that male birth control might be on the horizon? No?!Well, get ready, because while we've been busy living our lives, genomics has been moving – fast! Things that once read like science fiction are moving on over to the non-fiction section.This season on Nice Genes!, join Dr. Kaylee Byers as she engages in some big genomics breakthroughs – from personalized cancer treatments, to how our bodies react in space, to how animals adapt to the most extreme environments, and whether we can actually change how we age.It's a whole new gene-eration (if you will) of discoveries that you won't want to miss!New episodes every two weeks, starting September 8th. Make sure you follow Nice Genes! so you don't miss an episode!

August 20th, 2016. The Rogers K-Rock Centre, Kingston, Ontario. Thirty songs. Three encores, which was not a thing they did. And a country that put down whatever it was holding.Ten years later, jD asked fifteen people one question. Not what they made of it. Not where it ranks. Just this: where were you.The answers do not go where you would expect. An airplane hangar outside Olympia, Washington. A garage door in the country north of Superior with fifty people camped in the yard. A smoker in Calgary that had been running since sunrise. A lakeside deck in upstate New York with a bottle of Macallan 12 on it and a great blue heron that keeps turning up in the shape of an album cover. An arena in Chicago where a man from Detroit stood in a Gord Downie shirt underneath a Tigers jersey, missing the whole thing on purpose, waiting to find out whether two sentences he had typed five days earlier had reached anybody.They had. That is all yer getting.Who's HereAdam from Tampa had never seen The Hip play a note and owned five of the records. At 7:55 he told his houseguests he would be back in either five minutes or two and a half hours, went upstairs, and typed the words CBC and The Tragically Hip into a search bar. What he did the following morning cost him the next four years.Andy from London was three weeks deep into Scotland with a speaking gig in Pennsylvania waiting on the Monday. He flew home without his family for exactly one day. Where he watched it, and who was running the sound there, is the part that still gets him.Brian from Canastota got hooked by a Saturday Night Live performance in 1995 and never came unhooked. Bose rig on the deck, the lake in front of him, and a heron that has been showing up in a very particular silhouette for years. His wife found him out there at two in the morning.Brock from Kitchener was in the lower bowl. A ticket scanner went down and he ended up sitting inside a nearly empty K-Rock Centre while eight thousand people waited outside. Ten years on he has still never watched the broadcast. Not once, not one song.Colin from Winnipeg lost his mother and had his first child inside the same fortnight, and had to move a funeral to do it. He watched with a newborn who is ten years old now. He has a plan for the rewatch, and it involves all three kids.Dan from Buffalo and Colleen from Buffalo drove in from the Hamilton show with no tickets, no expectations, and their phones switched off at the border. Dan wandered down to look at a boat show at half past nine in the morning and got into a line without asking what the line was for. He was number twenty-eight.Duxoop from Toledo watched at home, alone, so that nobody could see him cry, pulling CBC down through a Windsor channel on Ohio cable. He knew twelve of the thirty songs that night. He is up to nineteen now, and the way he counts them is not the way you would count them.Greg from Tacoma spent the evening at his mother Rosalie's 79th birthday party in an airplane hangar, slipping off to a corner every ten minutes with a phone and no headphones. What he heard inside 'Grace, Too' that night he has never stopped hearing, and the people standing beside him in that hangar are a large part of why.Janice from Kitchener stopped for a photo at the Welcome to Kingston sign, signed the banners downtown, and walked into the arena at the exact moment it stopped letting anybody else in. She has a theory about how many people are eventually going to claim they were in that room.Jimmy from Detroit had tickets for the London and Toronto shows, and a promise to his wife that put him in Chicago on the 20th instead. Five days out he sat down and wrote two sentences on a message board. He will go to his grave believing somebody read them.Joanne from Thunder Bay had seen the August 12th show in Toronto and could not get to Kingston. A friend rigged a projector onto a garage door out in the country and fifty people camped in the yard to watch it. One song landed harder than everything around it, and it was not the closer.Spencer from Calgary made three racks of ribs, a couple dozen perogies by hand, and a house rule about side conversations. Gold glitter letters stuck to the fridge spelling out the songs he was hoping for. Then he walks the setlist album block by album block, and a decade later the surprises still surprise him.Steve from Toronto got a single ticket half an hour after they went on sale and watched from ten rows back. He has the sharpest disagreement in the whole episode, and it is not about the band. It is about whether the people watching it and the people inside it were even at the same event.Todd from Fort Mac says the words Fort Mac and 2016 and everybody already knows he means the fire. He watched at his grandfather's house in Louisdale, Cape Breton, with the family in from out west. It was the last time all of them were in that room together.What They Said"I'll start with the punchline, which was I was in an airplane hangar weeping."  - Greg from Tacoma"I went by myself, but I was not alone."  - Andy from London"When you're watching it on TV and Gord's breaking down at the end of the song, you feel completely helpless. But when you're at the show and that happens, you just start making as much noise as you know how to make to help your guy pull through."  - Steve from Toronto"To me, it's a celebration of Canadian culture. And I know that was never the intention, but it's just always what it turned out to be."  - Todd from Fort MacAbout That NightThirty songs at the Rogers K-Rock Centre. 'Fifty-Mission Cap' into 'Courage', 'Wheat Kings', and 'At the Hundredth Meridian' - four songs in and the whole country was already accounted for. Then 'Tired as Fuck', uncensored, on the national broadcaster. Then a thunderstorm nobody had been warned about. Then 'My Music at Work', 'Lake Fever', 'Toronto #4', and 'The Last of the Unplucked Gems', which is not a setlist, it is a dare. Three encores, closing on 'Ahead by a Century'. Setlist confirmed via setlist.fm.Fifteen people, one date, and not one of them tells it the same way. That is the whole point of this show, and Kingston is where it lands.GEDfest Toronto 2026Saturday, October 17th, 2026. The Horseshoe Tavern, Toronto, with Grace, 2 on the stage. GEDfest raises money for Campfire Circle and the Murphy Family Fund in Precision Medicine in Pancreatic Cancer, and this community has put nearly $40,000 toward causes like these since 2018. Tickets and details: facebook.com/GEDfestYYZThe CommunityYer Letter lands once a month with everything happening across the network. Subscribe at subscribe.tthpods.com. The Facebook group is roughly 7,500 fans deep and still climbing at community.tthpods.com. Leave yer own Hipstory any time - jD reads every one.Home: home.tthpods.comEmail: jd@tthpods.comInstagram: @tthpodsYouTube: youtube.com/@tthpodsTip JarEditing is hard and the battery needs charging. Buy jD a coffee at buymeacoffee.com/tthtop40More From The Final TourYer Hipstories: Reflections From The Final Tour - Ottawa: redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/7fb753ff-654b-4be4-ab44-3cbae3b7a68bYer Hipstories: Reflections From The Final Tour - Hamilton: redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/fae76ee3-738f-4007-80c8-7140729bb295ClosingThank you to Adam, Andy, Brian, Brock, Colin, Dan, Colleen, Duxoop, Greg, Janice, Jimmy, Joanne, Spencer, Steve, and Todd. Fifteen people handed over the most specific night of their lives and asked for nothing back. So there's that.#TheTragicallyHip #GordDownie #TTHPods #HipFans #CanadianMusic #InGordWeTrustSupport this podcast at — https://redcircle.com/tthtop40/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

In 2006, the Institute of Medicine published From Cancer Patient to Cancer Survivor: Lost in Transition, concluding that millions of Americans were surviving cancer only to find themselves navigating a healthcare system unprepared for life after treatment. The report challenged oncology to recognize that curing cancer was not the end of care, but the beginning of survivorship.This episode explores how the growing cancer survivorship movement exposed the long-term consequences of cancer treatment that medicine had largely overlooked. As survival rates improved following the National Cancer Act of 1971, millions of survivors faced chronic fatigue, neuropathy, infertility, cognitive impairment, financial hardship, employment discrimination, anxiety, depression, and post-traumatic stress. These were not rare complications. They became defining features of survivorship for many patients.Drawing on the work of oncologist Dr. Patricia Ganz, survivor advocate Ellen Stovall, and researchers, clinicians, and survivors across the country, the episode examines how survivorship research expanded beyond recurrence and mortality to include quality of life, psychosocial care, rehabilitation, and long-term follow-up. Their efforts helped establish survivorship care plans, multidisciplinary survivorship clinics, and a broader understanding that cancer affects every aspect of a person's life long after treatment ends.The episode also confronts persistent inequities in survivorship care. Insurance coverage often ends when treatment stops, supportive services remain inconsistent, financial toxicity continues to drive medical hardship, and racial, geographic, and socioeconomic disparities still influence who receives comprehensive follow-up care. For many survivors, finishing treatment simply marks the beginning of another struggle.Modern oncology increasingly recognizes that surviving cancer is measured by more than years of life. It is also measured by quality of life, dignity, access to care, and the ability to rebuild a future after treatment. That evolution remains one of the most significant legacies of the cancer survivorship movement.RELATED LINKSNational Academy of Medicine | ⁠From Cancer Patient to Cancer Survivor: Lost in Transition⁠National Cancer Institute Office of Cancer Survivorship⁠American Society of Clinical Oncology | Survivorship Compendium⁠CancerCare⁠HopeWell Cancer Support⁠National Coalition for Cancer Survivorship⁠FEEDBACKLike this episode? Rate and review The Cancer Mavericks: A History of Survivorship on your favorite podcast platform. For more information, visit CancerMavericks.com. Please send any questions to podcasts@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

August 18, 2016. Ottawa, the second last night, and two fans who were in that building take jD back inside - ten years to the day.Thursday, August 18, 2016. The Canadian Tire Centre, out past the ring of car dealerships in the west end, and The Tragically Hip had two nights left. Kingston was already a pipe dream by then. For most of the country, Ottawa was the last chance.Ten years to the day, jD sits down with two fans who were in that room. Shawn from Ottawa, who has been in this community since he was sixteen. And Justin from Bridport, who you know from Discovering Downie, and who only got to Ottawa because a stranger with long hair heard "Yer Favourites" playing over the PA at a dirt track in Vermont.Two ticket stories, and neither one lands where you would guess. Shawn's shows up in his inbox, out of a presale nobody has ever really talked about in public, and there is something waiting in the will call envelope that nobody warned him about. Justin's shows up from a man whose name he did not have yet. He said yes first and introduced himself second.The songs: Justin starts to say 'Grace, Too', catches himself, and lands somewhere else. Shawn takes a deep cut off "In Between Evolution", the first record that ever got its hooks into him. They both land on 'Summer's Killing Us', and Ottawa turned out to be the last place The Tragically Hip ever played it.Then they walk the set list, and it is not the greatest hits argument you would expect. 'Opiated' out of nowhere. Four from "In Between Evolution" and four from "Day for Night", and the moment mid-set when Shawn worked out that none of those songs were going to make it to Kingston. Justin honoured Gord's wishes and kept the phone in his pocket, right up until he didn't.There is the morning of the announcement, too. Justin spent it alone in a car in Vermont, listening to a DJ who could not finish a sentence, with nobody to call. Shawn spent it in a country where everybody already knew before he was properly awake. Ten years later, hearing each other's version, that gap is the thing that gets them both.And then there is what happened after the lights came up, which involves two flights of stairs, a room that was not supposed to be a party, and a conversation outside it with somebody's grandfather. That one belongs to Shawn.Two nights later, one of them was inside the K-Rock Centre, still convinced right up to the turnstile that his ticket could not possibly be real. The other was at a racetrack, deliberately not watching.THE PANEL• Shawn from Ottawa - on Hipbase since he was sixteen and the resident kid brother of that community. In the family section on the night. In Kingston two nights later on a ticket a stranger handed him for nothing.• Justin from Bridport - Discovering Downie panelist, and the PR guy, announcer, lawnmower, and toilet cleaner at a Vermont dirt track. The American in the upper bowl who felt Canadian for exactly one night.SOURCESSet list for August 18, 2016 at the Canadian Tire Centre in Ottawa, and the July 22, 2016 Victoria set list - source: setlist.fm. Thanks to Darren at The Tragically Hip Archive, and to the tapers, for the recordings Shawn listened back to before this one.THE GATHERING IN KINGSTONAugust 20 to 23, 2026, alongside Forever Hip - a mixer at the Merchant Pub, Choir! Choir! Choir! in Springer Market Square, a listening party for "The Tragically Hip Live, July 22 - August 20, 2016", a Long Time Running screening, and a farewell brunch at Morrison's. The CBC broadcast re-airs on the 22nd. Email jd@tthpods.com to get on the list. And if you spot a purple shirt or a purple lanyard in Kingston that weekend, that's a safe person to talk to.GEDFEST TORONTOSaturday, October 17, 2026 at the Horseshoe Tavern, with Grace, 2. Raising money for Campfire Circle and the Murphy Family Fund in Precision Medicine in Pancreatic Cancer. Tickets: facebook.com/GEDfestYYZThanks to Shawn and Justin, because without them, there's not a show. Next stop: Kingston, and the end of the line.MORE FROM THE TOURVictoria: https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/99071e40-9d10-48f8-9b5d-f92416e791c3Winnipeg: https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/bf776e9a-c431-41bc-b605-f73fff1155d3And because 'Gus: The Polar Bear from Central Park' turned up in the Ottawa set, The Tragically Hip On Shuffle - Live Stream: Gus: The Polar Bear From Central Park: https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/68d2991b-9074-43ef-bd71-aa832c59a787SUPPORT THE WORKThe tip jar: buymeacoffee.com/tthtop40Web: home.tthpods.com | Facebook: community.tthpods.com | Instagram: @tthpods | YouTube: youtube.com/@tthpods | Newsletter: subscribe.tthpods.com | Email: jd@tthpods.com#TheTragicallyHip #GordDownie #DayForNight #InBetweenEvolution #HipFans #TTHPodsSupport this podcast at — https://redcircle.com/tthtop40/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

In 1967, breast surgeon Dr. Harold P. Freeman arrived at Harlem Hospital expecting to treat cancer. Instead, he confronted a healthcare system where poverty, racism, lack of insurance, and institutional barriers often determined who lived long enough to receive treatment. Patients frequently arrived with advanced disease, not because medicine lacked answers, but because access to care had failed them.This episode explores how cancer survivorship expanded beyond medical breakthroughs to include healthcare access, health equity, and organized advocacy. Building on the early work of the National Coalition for Cancer Survivorship (NCCS), it examines the recognition that surviving cancer depended not only on research, but also on whether patients could navigate a fragmented healthcare system.Freeman responded by creating one of the nation's first patient navigation programs at Harlem Hospital in 1990. Community-based navigators helped patients overcome practical barriers including insurance, transportation, appointments, communication, and fear. The model dramatically improved timely diagnosis and treatment, increased breast cancer survival in Harlem, and ultimately inspired the Patient Navigator Outreach and Chronic Disease Prevention Act of 2005, establishing navigation as a cornerstone of modern oncology care.The episode also follows cancer survivor Ellen Stovall, whose leadership transformed survivorship into a national policy movement. Through the NCCS, she united advocates across cancer types, fought for insurance protections, expanded access to clinical trials, helped shape the creation of the Office of Cancer Survivorship at the National Cancer Institute, and organized the landmark 1998 National March for Cancer Survivorship in Washington, D.C. Her work reframed survivorship as a public policy issue rather than a personal experience.Together, Freeman and Stovall demonstrated that scientific progress alone could not eliminate disparities in cancer outcomes. Their work established two enduring principles that continue to shape oncology today: patients need someone to help them navigate care, and survivors must have a voice in the policies that govern it. Modern cancer survivorship depends on both.RELATED LINKSNational Coalition for Cancer Survivorship⁠Harold P. Freeman Patient Navigation Institute⁠National Cancer Institute Office of Cancer Survivorship⁠Patient Navigator Outreach and Chronic Disease Prevention Act of 2005⁠American Cancer Society⁠Tuskegee Study Timeline | Centers for Disease Control and Prevention⁠FEEDBACKLike this episode? Rate and review The Cancer Mavericks: A History of Survivorship on your favorite podcast platform. For more information, visit CancerMavericks.com. Please send any questions to podcasts@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

August 16, 2016. The Hip arrived in the Hammer, and three fans who were in the building take jD back inside - ten years to the day.Tuesday, August 16, 2016. FirstOntario Centre in Hamilton, four days out from the end of everything, and The Tragically Hip pulled into a city that watched them play to nobody once and never forgot it.Ten years to the day, jD sits down with three fans who were there for that room: Gino from Buffalo, Matt from Buffalo, and John from Mississauga. Two of them had never been on a podcast before in their lives. One of them never made it through the doors.The songs first, because the songs are always first. Gino takes 'Poets', the last one of the main set, the one where Gord stopped and told the room about The Hip's first Hamilton gig - a club, zero people, and an owner who told them nobody gets paid until every song gets sung. So they played another hour to an empty room. Ten years and a lifetime later, Gord looked out at a full arena and, the way Gino heard it, said something close to look at us, look at where we are now. Us, collectively. Hamilton and The Hip.Matt takes 'Scared', and the line it's been a pleasure doing business with you, and the small jump in the video he was shooting - the moment his buddy behind him lost his knees and fell into his back. John takes 'Courage', because of what it took Gord to get in the van at all. A residency somewhere would have been hard enough. He went across the country instead.Then the tickets, and three completely different scrambles. Matt's Buffalo crew split the presale up like a heist - one guy on London, one on each Toronto night, Matt on Hamilton - with orders that whoever got in bought all four. Matt was the only one who got into the queue, and he had four seats about ten minutes in. Gino got shut out in the fifteen minutes it took the show to vanish, then his friend Greg found VIP seats hours later and warned him they'd be expensive. Gino's answer: I don't care. Third row on the floor. If it was within a 500-mile radius, you weren't stopping me.The day itself: a friend on standby in Niagara Falls, U.S., in case one of Matt's four didn't clear the border, a cash-only scalper outside the arena with PDF printouts and a very loose grip on legitimacy, and their buddy Scott laying out most of the money for a pair of those dubious tickets so a friend from Lockport could drive up and slide in during the first song. Gino owns his company, so Gino gave himself the afternoon off, got to Hamilton by mid-afternoon, and ate Portuguese chicken at the Charred Rotisserie House down the road from the barn. We ate like kings. He has been back a few times since.And then there is John, who was downtown at the Toronto Stock Exchange that Tuesday, letting a vendor in to do a routine job. At 2:30 the vendor crashed the system. Eight hours to bring it back. John is standing on a floor you get onto with retina scans and palm prints, he cannot leave the vendor alone, and his company supplies data to the exchange at thousands of dollars an hour. He had a ticket in his pocket and a family carload heading to Hamilton without him. So he stood there and asked himself the only question he had. What would Gord do? What's the Canadian thing to do? He thought about '38 Years Old' - which is the plate on his car - and the father in that song who turns his own son in because it is the right thing. John stayed at his post. He called his sons and told them to give the ticket away. Every August 16th since has been one of the saddest days of his year.Inside the building, the two who made it describe the same night from two heights. The small stage, the band pressed in around each other, a band of brothers making life as easy for Gord as they could. Gord finding faces one at a time, holding them, nodding, gesturing, taking what Gino calls little memory snippets for himself. The monitor on the floor by his feet for the words that wouldn't come. Gino has seen this band more than forty times, and he puts Hamilton at the top for sheer energy. Matt's read is sharper still: the energy was all there, the memory just couldn't always match it.The set list gave Hamilton 'Fifty-Mission Cap', 'Eldorado', and 'At the Hundredth Meridian' early, four from "World Container" as the night's rare record, and the best four of the six "Man Machine Poem" songs that made the tour. 'Poets' to close the main set. 'Gift Shop', 'Don't Wake Daddy', and 'Ahead by a Century' in the first encore. Then 'Fiddler's Green' and 'Twist My Arm' in the second, and a song Gino had never heard live anywhere. Matt has one regret and it is a beer. He went for one during 'Escape Is at Hand for the Travellin' Man', found the concourse narrow and the taps in the basement, and came back up on 'Fireworks' having missed ten minutes he will never get back. So there's that.Gino's detour is worth the price of admission on its own - Highland Bowl in Rochester, a grass amphitheatre, a downpour with thunder and lightning, the band stopping for maybe ten minutes, Gord calling out to the lovers of music who stayed, and grown adults sliding down the wet hill on their bellies toward the stage. Second best night he ever had with this band. Hamilton was first.Then the lights. Gino describes an arena that felt like one family at a memorial service, except it wasn't a somber memorial service - it was everybody holding everybody else up while Gord stood there telling them from the stage that it was going to be okay. Half an hour after the last note the set list was sitting within arm's reach, so Gino took it, and they passed it around for photographs. Nobody wanted to leave. Matt walked over to the King George pub with seven other people and found something else entirely. It almost had the feeling of a wake. Nobody wanted another round. Everybody was thankful. Everybody knew.August 20th finds all three of them in very different rooms. John rigged an aerial in the backyard of his brother's cottage outside Montreal, set both PVRs at home, and asked the local bar in a small French-Canadian town whether they'd be showing it - they had no idea what he was talking about. Don't move that coat hanger outside. Matt spent three hours assembling a children's play kitchen for his two-year-old daughter with the broadcast on, which should have taken one. Gino watched with a dozen guys at a friend's place, where Greg leaned over and said the thing nobody else had thought: doesn't he look nervous? He did. Of course he did.The landing belongs to John, though. There was no goodbye for him that night, so it came slowly, over days and weeks, like a song fading out instead of ending. And it kept going. He has a nine-year-old granddaughter now who knows the words, and he took her to Chudleigh's in Milton to see the Practically Hip so she could dance to them. Another generation, flying the flag.THE PANEL• Gino from Buffalo - forty-plus shows with The Hip, third row on the floor in Hamilton on a VIP ticket his friend Greg found hours after the show sold out, and a plate of Portuguese chicken beforehand he still drives back for. He came home with the set list. He listens to this band every single day.• Matt from Buffalo - second row of section 120, with a photo from that night still hanging behind him on camera. He ran the Buffalo crew's presale plan, got the only four seats any of them landed, filmed 'Scared' through the moment his friend's knees went, and lost ten minutes of the night to a beer line in the basement.• John from Mississauga - the one who didn't get in. A crashed system on the Toronto Stock Exchange floor at 2:30 on show day, a ticket handed off to somebody else, and a decision he made by asking what Gord would do. He watched August 20th through a coat hanger aerial at a cottage. His granddaughter is nine and already knows the words.SOURCESSet list for August 16, 2016 at FirstOntario Centre in Hamilton (now TD Coliseum) - source: setlist.fm.THE GATHERING IN KINGSTONAugust 20 to 23, 2026, alongside Forever Hip - a mixer at the Merchant Pub, Choir! Choir! Choir! in Springer Market Square, a listening party for "The Tragically Hip Live, July 22 - August 20, 2016", a Long Time Running screening, and a farewell brunch at Morrison's. The CBC broadcast re-airs on the 22nd. Email jd@tthpods.com to get on the list. And if you spot a purple shirt or a purple lanyard in Kingston that weekend, that's a safe person to talk to.GEDFEST TORONTOSaturday, October 17, 2026 at the Horseshoe Tavern, with Grace, 2. Raising money for Campfire Circle and the Murphy Family Fund in Precision Medicine in Pancreatic Cancer. Tickets: facebook.com/GEDfestYYZThanks to Gino, Matt, and John, because without them, there's not a show. Next stop: Ottawa.MORE FROM THE TOURWinnipeg: https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/bf776e9a-c431-41bc-b605-f73fff1155d3Calgary Night 2: https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/98943c27-bdae-4f56-84d4-a57754be7719SUPPORT THE WORKThe tip jar: buymeacoffee.com/tthtop40Web: home.tthpods.com | Facebook: community.tthpods.com | Instagram: @tthpods | YouTube: youtube.com/@tthpods | Newsletter: subscribe.tthpods.com | Email: jd@tthpods.com#TheTragicallyHip #GordDownie #WorldContainer #RoadApples #HipFans #TTHPodsSupport this podcast at — https://redcircle.com/tthtop40/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

September 14th, 2009. Edmonton. The last time The Tragically Hip ever played 'Emperor Penguin', and not one person in that building knew it.Seventy-two performances. That's the whole run. The first on July 2nd, 1998, a couple of weeks before "Phantom Power" was even in stores, and the last one in Edmonton on the We Are The Same tour before the song went in a drawer for good. Justin pulled that off setlist.fm live on the stream, Hipbase backs it up, and it turned into the thing nobody saw coming, because one of the two guys at the table tonight is Shawn from Edmonton. He was at that show. He found out on mic.We're on a Thursday this week, which is the end of the Thursday experiment. Back to Wednesdays next week. It was nice while we had it.'Emperor Penguin' landed at number 32 on the TTHTop40 Countdown and neither panelist is at peace with it. One of them would have guessed somewhere around 65. The other would have shoved it higher. Nobody splits the difference. So there's that.Then we spin a live version from Massey Hall, 2009, and Gord introduces the song with a line about why they don't play it often that tells you everything about how the band felt about it. There's a ninety-second outro hanging off the back of it that belongs to Robbie and nobody else. And somewhere early on Gord comes in on the wrong verse and does something with the save that Justin had been chewing on all day before we even hit record.WHAT ELSE IS IN HERE• Two readings of the lyric that come at it from opposite ends and land in the same spot, and one of them hinges on which parent actually sits on the egg.• "I like the tone of your trumpet. Come on, let's spill some paint." The most abstract stretch on the whole record, a notebook theory, and a guess involving Josh Finlayson that may not survive contact with HipMuseum.• The late night call in radio show sitting underneath these lyrics, and the drive home through the Bible Belt that Justin still can't shake loose from this song.• Shawn plays bass, so he hears this as a Paul and Robbie record, with Gord Sinclair and Johnny Fay rock solid and deliberately out of the way. Then Robbie takes it home.• Steve Berlin, the first of his two with the band, and what having a producer in the room at the Bathhouse did to the atmosphere of this thing.• "Phantom Power" as the line in the sand. The last record of the first era, and what happened to a good chunk of the congregation immediately after it.• Shawn spent real time with the guys in the early days. Sound checks with six people in the room. Gord showing him the notebook. And a lyric on one of the most loved songs in the catalogue that he can tell you exactly where they were sitting when it came up. We get about ninety seconds of that story. It deserves its own episode, and we are going to get it.Next week is 'Tiger The Lion', which is track one on the record that follows the record that ends with this song. Brand new panel, brand new song, and yes, the shuffle is actually random. I promise.THE PANEL• Justin from Bridport, Vermont. He announces the sprint cars of New England, so if you're anywhere in the northeast, go find a dirt track. He's also a Discovering Downie panelist.• Shawn from Edmonton. The Port Bickerton Lighthouse Arts Festival goes August 24th in Port Bickerton, Nova Scotia, put on by the Port Bickerton Lighthouse Association. East Coast and Maritime acts, artists, and the biggest one they've done yet.THREE CHAIRS IN THE BATHHOUSEOn August 20th at 1:00 pm I'm filming the final episode of Yer Hipstories: Reflections From The Final Tour inside the Bathhouse in Bath, Ontario. Ten years to the day since Kingston. Three chairs are open to fans. Email jd@tthpods.com by August 15th with your name, email, phone number, whether you can be there in person, and a one minute video on why it should be you. Travel is on you. That's the only catch.THE GATHERING - KINGSTON, AUGUST 20 TO 23Alongside Forever Hip. A mixer at the Merchant Pub, Choir! Choir! Choir! in Springer Market Square, a listening party for "The Tragically Hip Live, July 22 - August 20, 2016", a screening of Long Time Running, the CBC re-airing on the 22nd, and a farewell brunch at Morrison's. Email jd@tthpods.com to get on the list.GEDFEST TORONTO - SATURDAY, OCTOBER 17The Horseshoe Tavern, with Grace, 2. Every dollar goes to Campfire Circle and the Murphy Family Fund in Precision Medicine in Pancreatic Cancer. Tickets through facebook.com/GEDfestYYZ.FIND USHome: home.tthpods.comEmail: jd@tthpods.comFacebook community: community.tthpods.comInstagram: @tthpodsYouTube: youtube.com/@tthpodsYer Letter: subscribe.tthpods.comTip jar: buymeacoffee.com/tthtop40MORE THE TRAGICALLY HIP ON SHUFFLE LIVE STREAM'Bobcaygeon': https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/dca7d1f5-6dea-4df8-b8d1-33008aa46cbd'Gus: The Polar Bear From Central Park': https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/68d2991b-9074-43ef-bd71-aa832c59a787Live performance counts and dates come from Hipbase and setlist.fm, as cited on the stream.#TheTragicallyHip #EmperorPenguin #PhantomPower #TTHPods #HipHeads #OnShuffleSupport this podcast at — https://redcircle.com/tthtop40/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Welcome to a very, very, very special bonus episode of Out of Patients, and one unlike anything published on this feed before. For nearly 20 years, Matthew Zachary has handed these microphones to patients, caregivers, doctors, advocates, troublemakers, and people with something worth saying. This time, he handed them to his daughter. Hannah Greenzweig grew up around this show, and now she has commandeered the studio with 3 of her wonderfully creative high school friends to talk about something they built entirely themselves. There is an enormous amount of Dad Pride baked into this episode, along with the strange and wonderful realization that sometimes your kid grows up, takes your chair, takes your microphone, and produces a better show without you.Hannah Greenzweig, Michael Aidinov, Gwendolyn Baldini, and Astronomy are student artists from the Roundabout Youth Ensemble at James Madison High School in Brooklyn. Working alongside teaching artists from Roundabout Theatre Company, they spent a school year creating an original play from the ground up, writing every scene, developing every character, and producing the performance themselves.Instead of discussing a Broadway production, they dissect one they invented.Their play, Subject Matter, began with a room full of improbable ideas. Murderous bounce houses, pirate family sagas, underwater adventures, courtroom dance battles, and birthday parties at math museums all competed before the group settled on an absurd rivalry between New York's fictional History Museum and Math Museum. From there, they built a fully staged comedy about institutional competition, sabotage, oversized personalities, and the unexpected discovery that history and mathematics need each other more than either side wants to admit.The conversation pulls back the curtain on a creative process most audiences never see. The students explain how scenes evolved through constant rewrites, how characters emerged from improvisation, how costumes came together with last minute ingenuity, and how rehearsals often collapsed into uncontrollable laughter. They recount cutting favorite ideas, solving production problems with limited resources, and trusting each other enough to keep rewriting until the story worked.The episode also captures something harder to script: teenagers speaking honestly about collaboration without adults translating their experience. They celebrate classmates who stepped into unexpected roles, teachers who quietly held the production together, and the strange joy of creating something that exists only because everyone showed up.It is a conversation about theater, friendship, education, creativity, and what happens when 4 young artists get the microphones and the adults get out of the way.RELATED LINKSRoundabout Theatre CompanyRoundabout Youth EnsembleJames Madison High SchoolFEEDBACKLike this bonus episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship email podcasts@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

August 14, 2016. The last night The Tragically Hip ever played Toronto, and three fans who were in the building take jD back inside - ten years to the day.Sunday, August 14, 2016. The Air Canada Centre, the last night of a three-night stand, and the last time The Tragically Hip ever played Toronto. Nobody in the building knew that for certain. Everybody in the building knew it anyway.Ten years to the day, jD steers into uncharted waters (they never do third ones) with three fans who were there: Dave from Thornhill, Jeff from Buffalo, and Jeff from Belleville.The news first, because the news is always first. Jeff from Buffalo came in from a morning run, read the email, and handed his wife the phone because he could not say the words. Dave was getting into his car at Yonge and Eglinton when his whole body sank (and one friend in the group chat skipped the first paragraph and celebrated the new tour - leave it to friends). Jeff from Belleville read it in the front foyer, flashed hot, and told his kids the only thing he could get out: Gord Downie is not doing well.Then the tickets. Jeff from Buffalo broke the algorithm by asking for one seat at a time - it kept offering him another, and two shutouts became four tickets. Dave had Kingston floors on his screen for five full minutes before the error message took them away. Jeff from Belleville stared down the spinning wheel of death for half an hour, then went to plan B. Plan B was this show. So there's that.The day itself: the recording booth outside the ACC that both Jeffs walked past and still regret, a stranger in the beer line who covered the round - "pay it forward, man" - and got the two people behind them too, and Dave breaking his own no-listening-on-show-day rule, blasting The Hip the whole drive down from camp in Haliburton before standing under the marquee, staring at the boys.Then the set list. 'Blow at High Dough' out of the gate, hitting everybody in the face exactly the way it should. 'Opiated', which Dave still can't quite believe he got. Four songs from "Now For Plan A", the rare record of the night. 'The Last of the Unplucked Gems' filling the room while Gord changed - reflection time, Dave calls it. The 'that night in Toronto' line in 'Bobcaygeon' that Gord missed and the whole building carried. And 'Daredevil' into 'Grace, Too' to close - the close-up on the big screen, everything pouring out of him, down to the last bead of sweat.Jeff from Buffalo kept notes from that week, and he read them back. Nervous on the QEW. No crying at the show. And one line that says it all: there's no way he's sick, because nobody sick could be that defiant. The whole evening was a magic spell, and it held right up until the house lights came on. Then it broke.There's a detour into the silver suit (hello, good evening folks, we are the Silver Poets) - armor, magician's misdirection, or just Gord radiating light in a purple hat, depending on which panelist you ask. Jeff from Belleville admits the outfits looked a little cringy in the photos beforehand. Then Gord strutted out. Case closed.And the thread runs where it always runs - to August 20th. A living room outside Buffalo with the kids and Pearl Jam dedications rolling in. The back of the floor at the Danforth Music Hall. And for Dave, a mystery ticket a few weeks later that turned out to be "Secret Path" at Roy Thomson Hall - which he now teaches to his grade 7 and 8 students every January, when it's cold and grey outside and Chanie Wenjack was about their age.The landing belongs to Jeff from Buffalo, though: a compromised man put on a show like that, and the rest of us have our health. We all have something terminal. Live like it.THE PANEL• Dave from Thornhill - a teacher who got one night away from camp in Haliburton and spent it at the last Toronto Hip show, watched Kingston floors dissolve into an error screen, and turned a mystery ticket into "Secret Path" at Roy Thomson Hall. His debut novel, "The Throwback Academy", arrives this October under the pen name TJ Thompson (Instagram: @tjthompsonbooks).• Jeff from Buffalo - four kids (including triplets), a ticket system broken one seat at a time, and notes written in 2016 that he read back on air. He writes feature stories for Buffalo Magazine - the newest one is about washed glass on the Lake Erie shore.• Jeff from Belleville - an hour and forty from home with his wife, Shannon, a plan-B ticket that turned into this episode, and the beer-line story this series will be retelling for a while. His internet fought him all night. He stayed anyway.SOURCESSet list for August 14, 2016 at the Air Canada Centre - source: setlist.fm.SIT IN THE THIRD CHAIRThe finale of Yer Hipstories: Reflections From The Final Tour films inside the Bathhouse in Bath, Ontario on August 20, 2026 at 1:00 pm - ten years to the day since Kingston. There are three fan chairs, and one of them could be yours. Email jd@tthpods.com by August 15 - the day after this episode drops - with your name, email, phone number, whether you can make it to Bath, and a one-minute video on why it should be you. Travel is on you. The chair is on jD.GEDFEST TORONTOSaturday, October 17, 2026 at the Horseshoe Tavern, with Grace, 2. Raising money for Campfire Circle and the Murphy Family Fund in Precision Medicine in Pancreatic Cancer. Tickets: facebook.com/GEDfestYYZTHE GATHERING IN KINGSTONAugust 20 to 23, 2026, alongside Forever Hip - a mixer at the Merchant Pub, Choir! Choir! Choir! in Springer Market Square, a listening party for "The Tragically Hip Live, July 22 - August 20, 2016", a Long Time Running screening, and a farewell brunch at Morrison's. Email jd@tthpods.com to get on the list. And if you spot a purple shirt or a purple lanyard in Kingston that weekend, that's a safe person to talk to.Thanks to Dave, Jeff, and Jeff, because without them, there's not a show. Next stop: Hamilton - the show Dave almost talked himself into.MORE FROM THE TOURVictoria: https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/99071e40-9d10-48f8-9b5d-f92416e791c3Winnipeg: https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/bf776e9a-c431-41bc-b605-f73fff1155d3SUPPORT THE WORKThe tip jar: buymeacoffee.com/tthtop40Web: home.tthpods.com | Facebook: community.tthpods.com | Instagram: @tthpods | YouTube: youtube.com/@tthpods | Newsletter: subscribe.tthpods.com | Email: jd@tthpods.com#TheTragicallyHip #GordDownie #ManMachinePoem #NowForPlanA #UpToHere #TTHPodsSupport this podcast at — https://redcircle.com/tthtop40/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

A man is struck by a car on the streets of Los Angeles. In the emergency department, a CT scan ordered to look for traumatic injuries reveals something nobody expected: a mass in his colon. Days later, sitting across from Dr. Belinda Waltman, he calls the accident “a blessing in disguise.” Then he changes the subject. He is less worried about cancer than about whether he can afford to miss another day of work. In this season finale of Standard Deviation, host Dr. Oliver Bogler explores what happens when biomedical science collides with the realities of the healthcare safety net. Dr. Waltman, a primary care physician in Los Angeles County, specializes in expedited cancer workups for uninsured and underinsured patients. Every diagnosis arrives carrying another set of questions about housing, transportation, food insecurity, wages, and survival that rarely appear in medical records or scientific literature. For years, Waltman carried those stories without knowing how to bring them into the academic record. As a full-time clinician without a research lab, grant funding, or publication pipeline, she faced barriers familiar to many working scientists and physicians whose most important observations happen outside traditional research settings. With support from the Life Science Editors Foundation's JEDI program, those experiences became The Margins Matter, a narrative medicine essay published in JAMA that argues the social realities surrounding cancer care are not background details. They are part of the disease itself. Bogler traces how editorial mentorship transformed lived clinical experience into published scholarship while asking a larger question about who gets to shape the scientific record. The conversation examines cancer care, Medicaid, health-related social needs, medical publishing, and the structural incentives that determine which stories become evidence and which disappear from view.The result is a conversation about documentation, visibility, and why the margins of medicine often determine who survives long enough to benefit from its advances.RELATED LINKSDr. Belinda Waltman⁠The Margins Matter | JAMA⁠The Margins Matter | PubMed⁠Life Science Editors Foundation⁠FEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship email podcasts@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

August 12, 2016. Night two of three at the Air Canada Centre. The rare record is "In Violet Light", and four fans who were in the building take jD back.Friday, August 12, 2016. The Air Canada Centre, night two of three - the middle child of the Toronto stand, the night Patrick calls the forgotten one. Which is a strange thing to call a show Steve ranks, out of the 32 Hip shows he saw, as the best one. Not the biggest. Not the saddest. The best.Ten years to the day, jD sits down with four fans who were in the building - Brian from Buffalo, Steve from Toronto, Patrick from Newmarket, and Katrusia from Hamilton. (He was there too. He'll get into that another time.)Brian opens with something he says he has never told anyone - not on the Hipbase, not even his wife. He heard the rumour about Gord months before the announcement, and spent that winter connecting dots he did not want to connect. Katrusia heard the news on CBC, which felt fitting. Patrick read the email in a newsroom, surrounded by people who suddenly had to cover the story he was living.The ticket tales alone are worth the price of admission (which, for this panel, was face value across the board - a point of pride). A friend in House of Blues accounting. A table in the Air Canada Club. Steve watching night one from the gondola - a bird's eye view of a bird's eye view - and securing his night two seat from a location he is brave enough to name on the record. So there's that.Then the set list. 'Courage' into 'Locked in the Trunk of a Car' into 'Eldorado' to open. 'Membership', the white whale, finally landed for two of the four. 'Throwing Off Glass', live, in 2016. 'What Blue' making its case as the best of the final stretch. 'Grace, Too' carrying more weight than anyone was ready for. And 'Ahead by a Century' to close - a strange choice until it wasn't, with every person in the building on their feet, singing every word.The panel follows the thread to August 20th - two bottles of wine and a laptop in a Buffalo living room, a three-hour detour to stand alone under the Bobcaygeon sign, pizza in residence and pints at the Brass in Kingston - and lands where this series keeps landing. You never regret the shows you see. You regret the ones you miss.(Also, one of these panelists played a living-room concert for a baby who has not arrived yet, and the first song was 'Wheat Kings'. You'll hear it.)THE PANEL• Brian from Buffalo - 54 Hip shows, a "Phantom Power" diehard, and a teacher who crossed the border for this band for years. 'Membership' was the last "Phantom Power" song he had never heard live. Not anymore.• Steve from Toronto - 32 Hip shows, engaged that Canada Day, and proof that "In Violet Light" belongs to Kingston in the summer of 2002. He calls this the best Hip show he ever saw.• Patrick from Newmarket - five of the final six shows, every ticket at face value, a journalist brain that deletes nothing, and a 25-year chase for 'The Luxury' that ended on night one of this stand.• Katrusia from Hamilton - a deadhead family (buy and sell for face only), four shows on this tour, and a 2009 wedding themed to 'That Night in Toronto'. She got 'Bobcaygeon' at this one, standing next to the man she married.SOURCESSet list for August 12, 2016 at the Air Canada Centre - source: setlist.fm.SIT IN THE THIRD CHAIRThe finale of Yer Hipstories: Reflections From The Final Tour films inside the Bathhouse in Bath, Ontario on August 20, 2026 at 1:00 pm - ten years to the day since Kingston. There are three fan chairs, and one of them could be yours. Email jd@tthpods.com by August 15 with your name, email, phone number, whether you can make it to Bath, and a one-minute video on why it should be you. Travel is on you. The chair is on jD.GEDFEST TORONTOSaturday, October 17, 2026 at the Horseshoe Tavern, with Grace, 2. Raising money for Campfire Circle and the Murphy Family Fund in Precision Medicine in Pancreatic Cancer. Tickets: facebook.com/GEDfestYYZTHE GATHERING IN KINGSTONAugust 20 to 23, 2026, alongside Forever Hip - a mixer at the Merchant Pub, Choir! Choir! Choir! in Springer Market Square, a listening party for "The Tragically Hip Live, July 22 - August 20, 2016", a Long Time Running screening, and a farewell brunch at Morrison's. Email jd@tthpods.com to get on the list.Thanks to Brian, Steve, Patrick, and Katrusia, because without them, there's not a show. Next stop: Toronto Night 3 - the night the concourse became a puddle.MORE FROM THE TOURWinnipeg: https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/bf776e9a-c431-41bc-b605-f73fff1155d3Calgary Night 2: https://redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/98943c27-bdae-4f56-84d4-a57754be7719SUPPORT THE WORKThe tip jar: buymeacoffee.com/tthtop40Web: home.tthpods.com | Facebook: community.tthpods.com | Instagram: @tthpods | YouTube: youtube.com/@tthpods | Newsletter: subscribe.tthpods.com | Email: jd@tthpods.com#TheTragicallyHip #GordDownie #ManMachinePoem #InVioletLight #HipFans #TTHPodsSupport this podcast at — https://redcircle.com/tthtop40/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

GLPs are everywhere right now — but do you actually know what they are or what they do? In this episode I break down the reality of GLP-1, what it is, how it works, and how your body already has the natural ability to activate it through a fasting-focused lifestyle. Whether you're considering the shot or just curious about how it all works, this episode gives you the full picture so you can make the best decision for your health and future. _____ Are you ready for real, compassionate support on your fasting journey from someone who has actually lived it? I've shed over 200 pounds through fasting and have maintained it through some of the hardest seasons of life. If you're tired of doing this alone, you don't have to anymore. Come find your people: The Fasting Support Club _____ REFERENCES Habener, J.F. (2004). The discovery of glucagon-like peptide 1. ScienceDirect — Molecular and Cellular Endocrinology. Retrieved from sciencedirect.com Mass General Brigham Newsroom. (2025). Joel Habener receives Breakthrough Prize in Life Sciences for contributions to GLP-1 medications. Retrieved from massgeneralbrigham.org Journal of Clinical Investigation. (2024). Joel Habener, Svetlana Mojsov, and Lotte Bjerre Knudsen awarded Lasker Prize for pioneering work on GLP-1. Retrieved from jci.org Eng, J. (1992). Discovery of exendin-4 in Gila monster venom. VA Medical Center, Bronx, NY. Referenced in: PlexusDx. (2026). History of GLP-1 drugs: Complete timeline from exenatide to tirzepatide. Retrieved from plexusdx.com Fella Health. (2025). What is GLP-1 lizard venom: Gila monster discovery to diabetes drugs. Retrieved from fellahealth.com U.S. Food and Drug Administration. (2005). Approval of exenatide (Byetta) for type 2 diabetes. FDA Drug Approval Database. Acosta, A. & Ghusn, W. (2023). Semaglutide shown to be effective for weight loss in multicentre, one-year real-world study. European Congress on Obesity (ECO2023). Presented by Precision Medicine for Obesity Program, Mayo Clinic. Retrieved from eurekalert.org Mayo Clinic Press. (2026). Health benefits of semaglutide beyond weight loss. Retrieved from mcpress.mayoclinic.org National Institutes of Health / NCBI. (2024). Patient perceptions of Ozempic (semaglutide) for weight loss: Mixed methods analysis of online medication reviews. Retrieved from ncbi.nlm.nih.gov National Institutes of Health / NCBI. (2024). Evaluation of pre-treatment assessment of semaglutide users: Balancing the benefits of weight loss vs. potential health consequences. Retrieved from ncbi.nlm.nih.gov Fung, J. (2016). The Obesity Code: Unlocking the secrets of weight loss. Greystone Books. Fung, J. (2025). The Hunger Code: Resetting your body's fat thermostat in the age of ultra-processed food. Greystone Books.

In 1986, 23 survivors, physicians, nurses, attorneys, and community organizers gathered in Albuquerque, New Mexico, for a weekend that would permanently change the language and politics of cancer. Working late into the night, they debated not only strategy, but identity, ultimately declaring that from the moment of diagnosis, every person with cancer is a survivor.This episode traces the social and political forces that gave birth to the modern cancer survivorship movement. As advances in early detection and treatment allowed more people to live beyond cancer, survivors discovered that finishing treatment did not mean returning to normal life. Many faced employment discrimination, loss of insurance, social stigma, infertility, chronic health complications, and a healthcare system that viewed survival as the end of care rather than the beginning of a new chapter.Against the backdrop of the civil rights, disability rights, and community health movements of the 1960s and 1970s, physicians, activists, and survivors challenged medicine's paternalistic culture and demanded a greater voice in decisions affecting their lives. Central to this story are physician and survivor Dr. Fitzhugh Mullan, whose landmark 1985 essay, Seasons of Survival, redefined survivorship as a lifelong continuum, and community organizer Katherine Logan, whose determination united dozens of grassroots organizations into what became the National Coalition for Cancer Survivorship.The coalition's founding established principles that continue to shape oncology today. Survivors were no longer defined solely by disease or treatment outcomes. Their experiences became evidence. Their voices became essential to clinical research, healthcare policy, and patient advocacy. By redefining survivorship as an ongoing experience rather than a destination, the movement challenged medicine to recognize the lasting physical, emotional, financial, and social consequences of cancer.The ideas forged during that weekend in Albuquerque became the foundation of modern cancer survivorship. Nearly 40 years later, the coalition's defining principle, that survivorship begins at diagnosis, continues to influence cancer care, research, policy, and the way millions of people understand life after cancer.RELATED LINKSNational Coalition for Cancer Survivorship⁠National Cancer Institute Office of Cancer Survivorship⁠The New England Journal of Medicine⁠Americans with Disabilities Act (ADA.gov)⁠Library of Congress | Civil Rights History Project⁠White Coat, Clenched Fist by Fitzhugh Mullan⁠FEEDBACKLike this episode? Rate and review The Cancer Mavericks: A History of Survivorship on your favorite podcast platform. For more information, visit CancerMavericks.com. Please send any questions to podcasts@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Tragically Hip Day in Toronto. 'The Luxury' out of the gate, a tour debut in the encore, and a family of four in seats a text message unlocked.DescriptionAugust 10th, 2016. The Air Canada Centre - the first of three Toronto nights on the Man Machine Poem Tour, and the day Ernie from Denville, New Jersey woke up in his hotel room, flipped on the news, and heard the mayor declare it Tragically Hip Day before he had even gotten out of bed. He had flown up alone for his first-ever Canadian show, eleven club nights deep. The city was already celebrating.Then the lights come up and it is 'The Luxury'. Ernie had waited eleven shows to hear it. Jeff from Vaughan, following this band since 1992, can count the times he has heard it live on one hand. Two songs later comes 'Fiddler's Green', and Scott from Huntsville is looking at grown men crying as far as he can see, understanding exactly how the night is going to go. Third song in. They could do whatever they wanted.The roads in are half the story. Everybody got the same email on the Tuesday morning after the May long weekend - the news of Gord Downie's diagnosis, and a tour nobody knew how to feel about. Scott locked down Kingston hotel rooms before tickets even went on sale, then sweated out the Ticketmaster scramble for four Toronto seats - the morning after watching John Mann and Spirit of the West play a fundraiser at the Horseshoe Tavern, two Canadian heartbreaks stacked onto one walk home. Jeff sent a hockey dad four paragraphs about his life following The Hip, hoping to bring his wife and two kids, and got the answer every fan dreams about: they're yours. Which is how, during 'Fifty-Mission Cap', with Bill Barilko's banner up in the rafters, Jeff came to be filming a verse and then swinging the camera around to catch both his kids singing it back.There is a lot of night in here. 'Nautical Disaster' landing in the first encore as a tour debut (confirmed via setlist.fm, and backed by the notebook Ernie filled out that same evening). The crowd carrying the Toronto line in 'Bobcaygeon', the way Scott remembers it. The “Phantom Power” pair that closed the building down. And then the back half of the conversation jumps ahead to August 20th - Scott behind the stage in Kingston, not breathing until the scanner turned his print-off ticket green, Jeff front row in front of Robby Baker for show number 93, and Ernie back in New Jersey with the Kingston broadcast on the big screen and his son beside him.Somewhere in the middle of it, Scott sums up the entire summer in one sentence: “I've never been so excited for something I didn't want to happen.” So there's that.The panelErnie from Denville, New Jersey - eleven Hip shows in clubs from New York City to Syracuse before this one, his first in Canada and his first in an arena, solo in section 313 and never once feeling alone. His daughter has since become one of The Hip's biggest listeners on Apple Music. He also made a horror movie, We Can't Leave, streaming on Amazon Prime (sequel already in the hopper).Scott from Huntsville - travels to Hip shows with his wife and his oldest concert buddy, and hit Toronto Nights 1 and 3 plus Kingston on the final tour, where his kids texted mid-show to check on him. He chairs the Huntsville Festival of the Arts, a year-round festival bringing Canadian acts to Muskoka - huntsvillefestivalofthearts.com.Jeff from Vaughan - following The Hip since 1992, with Kingston set to be show number 93. He did London, multiple Toronto nights, Hamilton, and Kingston on the final run in a custom “Live Between Us” shirt, and brought his wife and both kids to Toronto Night 1. David Bastedo photographed the four of them in their row and sent it to him after the show.Come say hiThe Gathering in Kingston, August 20th to 23rd - a mixer at the Merchant Pub, Choir! Choir! Choir! in Springer Market Square, a listening party for “The Tragically Hip Live, July 22 - August 20, 2016”, a Long Time Running screening, and a farewell brunch at Morrison's. Email jd@tthpods.com to get on the list.GEDfest Toronto - Saturday, October 17th at the Horseshoe Tavern with Grace, 2, raising money for Campfire Circle and the Murphy Family Fund in Precision Medicine in Pancreatic Cancer. Yes, the same room John Mann played the night before the on-sale. That building keeps showing up. Tickets: facebook.com/GEDfestYYZClosingThanks to Ernie, Scott, and Jeff for bringing August 10th back - the flag, the notebook, the kids checking in on their dads. The Tragically Hip play the same building two nights later. Toronto Night 2, August 12th, brand new panel. We go again.More from the seriesVictoria, where the final tour began: redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/99071e40-9d10-48f8-9b5d-f92416e791c3Calgary Night 1, from earlier on the run: redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/2937266e-6c5a-4435-87a8-dcc35b478f37CommunityFacebook community: community.tthpods.comInstagram: @tthpodsYouTube: youtube.com/@tthpodsYer Letter: subscribe.tthpods.comEmail: jd@tthpods.comTip jar (tips, never donations): buymeacoffee.com/tthtop40#TheTragicallyHip #GordDownie #ManMachinePoem #DayForNight #PhantomPower #TTHPodsSupport this podcast at — https://redcircle.com/tthtop40/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Clinicians and medical providers rely on data to tailor care plans to their patients. Aartik Sarma, MD, University of California, San Francisco, Pat Lyons, MD, Oregon Health & Science University, and host Lekshmi Santhosh, MD, the University of California, San Francisco, discuss the use of data science in critical care medicine and how it has evolved over time. They dive into how new technologies benefit ICU patients, and how the medical infrastructure can be further improved.

Three fans - one in the penalty box, one in the last row, one from down the street - relive the night The Hip said goodbye to London.DescriptionAugust 8th, 2016. Budweiser Gardens, London, Ontario - show nine of the Man Machine Poem Tour, and the last night The Tragically Hip would ever play that city. The lights drop, the band walks out, and the first song is 'Opiated'. Wade had more than 40 Hip shows under his belt and had never heard them open with it. Not once. That kind of night.This one is a full table - three Hipstories from three corners of the map. Dave from St. Louis made the 13-hour drive one week after hernia surgery, found two tickets through a fellow fan on the Facebook forum after a StubHub snafu, called ahead about a wheelchair, and walked out with penalty box seats 15 rows from the stage. Treated, in his words, like royalty. Dan from Buffalo rode in with his brother Matt - the same brother who took him to his first Hip show at the Aud in 1995 - on the way to London, Hamilton, and eventually Kingston. And Wade from London didn't have to travel at all. His city, his buddies up from Leamington, dinner on a patio two blocks from the arena with The Hip on the speakers.The panel walks the whole night. The pause after "I'll die before I quit" in 'It Can't Be Nashville Every Night', and the roar that filled it. "It's been a pleasure doing business with you" landing like a ton of bricks in 'Scared'. 'Pigeon Camera' in the first encore, and Wade suddenly finding dust in the air. The four-songs-per-album architecture of the set, the rarely played "In Between Evolution" material, and the 'Little Bones' that was planned for the night and never came - Gord stepping to the mic instead to thank London and remember the first time The Hip played there, when nine people showed up. Why no 'Little Bones'? The way Dave heard it, it had everything to do with keeping Johnny Fay healthy. So there's that.Then the ride home. A living wake that turned into a celebration, a 12-round boxing match where everybody came out a winner, and two separate no-tickets pacts - one made in London, one in Buffalo - that would carry all three of these guys to Kingston on August 20th. But that's a story the episode tells better.(Setlist details confirmed via setlist.fm - right down to the extended 'Daredevil' outro Dave remembered correctly.)The panelDave from St. Louis - a diehard from the middle of America who has chased The Hip through Chicago, Detroit, and Dallas, and who streamed the Kingston broadcast with friends from his living room on August 20th, 2016.Dan from Buffalo - first show at the Aud in 1995, three stops on the final tour, 28th in line the morning Kingston released 200 tickets, and visible in Long Time Running during 'Courage', singing in the front row of the penalty box.Wade from London - 40 plus shows, from a bouncer-assisted first night at Royal Oak at 17 to Budweiser Gardens, introduced to the band by the cassettes his brother brought home from Western on laundry weekends.Come say hiThe Gathering in Kingston, August 20th to 23rd - a mixer at the Merchant Pub, Choir! Choir! Choir! in Springer Market Square, a listening party for "The Tragically Hip Live, July 22 - August 20, 2016", a Long Time Running screening, and a farewell brunch at Morrison's. Email jd@tthpods.com to get on the list.GEDfest Toronto - Saturday, October 17th at the Horseshoe Tavern with Grace, 2, raising money for Campfire Circle and the Murphy Family Fund in Precision Medicine in Pancreatic Cancer. Tickets: gedfest. caGrace, 2 in London - Friday, August 21st at London Music Hall, playing this very setlist front to back. Wade's plug, and a good one.ClosingThanks to Dave, Dan, and Wade for bringing August 8th back to life - the wheelchair, the pacts, and the dust in the air. The reflections roll on down the 401 next time.More from the seriesVictoria, where the final tour began: redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/99071e40-9d10-48f8-9b5d-f92416e791c3Calgary Night 1, the latest stop: redcircle.com/shows/a01e8de3-1a04-4a44-ab9c-8fc6e3cb7474/ep/2937266e-6c5a-4435-87a8-dcc35b478f37CommunityFacebook community: community.tthpods.comInstagram: @tthpodsYouTube: youtube.com/@tthpodsYer Letter: subscribe.tthpods.comEmail: jd@tthpods.comTip jar: buymeacoffee.com/tthtop40#TheTragicallyHip #GordDownie #ManMachinePoem #HipFans #TTHPods #CanadianMusicSupport this podcast at — https://redcircle.com/tthtop40/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

In 1971, President Richard Nixon signed the National Cancer Act, transforming cancer research with an unprecedented federal investment and launching what became known as the War on Cancer. The legislation did not emerge from scientific discovery alone. It was the culmination of decades of relentless advocacy by researchers, philanthropists, journalists, and patients who believed cancer demanded the same national commitment that had put astronauts on the Moon.This episode traces the origins of the cancer survivorship movement by returning to a time when cancer was rarely discussed in public, many physicians withheld diagnoses from their patients, and surgery offered few lasting cures. It follows the pioneering work of pathologist Dr. Sidney Farber, whose early chemotherapy research challenged conventional thinking, and Mary Lasker, whose political strategy, fundraising, and public campaigns helped transform cancer from a private tragedy into a national public health priority. Together, they built the coalition that reshaped federal support for oncology research and forever changed the relationship between science, government, and the American public.The story then turns to journalist and breast cancer survivor Rose Kushner, whose refusal to accept the standard one-step radical mastectomy challenged nearly a century of surgical dogma. Working alongside surgeon Dr. Bernard Fisher, Kushner helped bring evidence-based medicine to breast cancer treatment through randomized clinical trials that demonstrated less invasive surgery could achieve equivalent outcomes. Their efforts changed clinical practice, strengthened informed consent, and helped establish the principle that patients should participate in decisions about their own care.The breakthroughs explored in this episode extended far beyond new treatments. They redefined the role of patients in medicine, accelerated clinical research, and laid the foundation for modern cancer survivorship. The movement that followed would not simply help more people live longer. It would change what surviving cancer meant.RELATED LINKSNational Cancer Institute⁠National Cancer Act of 1971⁠American Cancer Society⁠Dana-Farber Cancer Institute⁠National Library of Medicine⁠The New England Journal of Medicine⁠FEEDBACKLike this episode? Rate and review The Cancer Mavericks: A History of Survivorship on your favorite podcast platform. For more information, visit CancerMavericks.com. Please send any questions to podcasts@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The review ran with no star rating. Infinite stars out of five. Four fans who were inside the MTS Centre explain why that was the only honest math.Episode summaryAugust 5th, 2016. A Friday night, show eight of the Man Machine Poem Tour, and the MTS Centre sits smack in the middle of downtown Winnipeg with no room to breathe. The Tragically Hip open with four straight from "Fully Completely", and the second song is 'Pigeon Camera' - a tour debut nobody in the building saw coming. Ten years on, four fans who were there pass the night around the table with jD.Nicole from Winnipeg raised three daughters on this music and lived her whole life in Thunder Bay before Winnipeg claimed her. She loaded two teenagers into the car and drove eight hours west so her girls could finally see the band she had been singing to them since the car seat. Somewhere in the causeway, the opening notes of 'At the Hundredth Meridian' hit, and the cranky seventeen-year-old looked at her mother and got it.Kim from Cambridge has 41 Hip shows on her card, and Winnipeg came with a bonus night. Same hotel as the band, a waiter's tip to come back to the bar later, a hundred-dollar bar tab worth of nerve, and then a gracious Rob Baker outside the bathroom, a sit-down with Gord Downie's bus driver, and a photo with Gord Sinclair. The guitar picks Bernie Breen handed over are framed with her tour poster.Dave from Montreal got the email on a beach in Crete, day two of a vacation that never recovered. He went to seven shows on the final tour, and this one meant the most - August 5th was the one-year anniversary of his mother's passing. He landed from Calgary on a WestJet flight full of Hip fans, caught the band's tweet about seats beside the stage, and cabbed straight from the airport to the box office. In the hotel lobby he told Paul Langlois that 'Three Pistols' had dodged him for 65 shows. "I can promise you you're going to hear it," Paul said.Alicia from Winnipeg heard the news before almost anybody, because breaking news was her job - she was the editor at Metro Winnipeg. She reviewed the show on deadline, one ticket, scribbling in a row of stunned critics, and filed it with no star rating at all. Infinite stars out of five. You can't score a goodbye.They talk about the four-song "Now for Plan A" block and what it asked of the room. About Gord Downie stopping the show to thank the Winnipeg people who built the band an audience, and a local music writer's phone detonating in real time. About the scream at the end of 'New Orleans Is Sinking' that shut an entire arena up, Kim's Periscope stream that died the moment 'Springtime in Vienna' made holding a phone still impossible, and the moment Dave realized the rants were gone - no workshopping, because there was nothing coming next. And about August 20th, which found them in a second row in Kingston, a basement watch party, and a raucous Thunder Bay bar called The Foundry.Nobody at this table claims the full picture. They just know what that room felt like, and ten years has not dulled it. This is the Winnipeg night, told back by the people who lived it.Key takeaways• 'Pigeon Camera' and 'Streets Ahead' were both tour debuts that night, and the setlist held five songs from "Road Apples" and nothing from "Day for Night" - Calgary got that block two nights earlier (source: setlist.fm).• Kim from Cambridge spent the night before the show in the band's hotel bar. Rob Baker was gracious, a bus driver made the introductions, Gord Sinclair posed for photos, and Bernie Breen handed out guitar picks.• Dave from Montreal traded up to seats beside the stage the day of the show off a band tweet, then put his spare pair on StubHub at face value. He did it again in Hamilton and Ottawa. Ten years later, he is finally telling that secret.• Gord stopped the Winnipeg show to thank the local supporters who built the band an audience there - the panel can only remember it happening one other place, Hamilton. One Winnipeg music writer's phone exploded on the spot.• The night before the show, a Winnipeg lawyer fighting the same brain cancer threw a fundraiser - and the man Nicole from Winnipeg would marry years later was onstage in the band that played it.• Alicia from Winnipeg filed her Metro Winnipeg review as infinite stars out of five, and a Winnipeg Free Press reviewer independently refused to put a number on it too. https://web.archive.org/web/20160807202054/http://www.metronews.ca/news/winnipeg/2016/08/06/review-at-the-hundredth-meridian-tragically-hip.htmlQuotes“I always thought we had more time.”Nicole from Winnipeg“I said, infinite stars out of five, because there's no way to do it, whether you're a Hip fan or not.”Alicia from Winnipeg“When he stepped out in that green suit and just commanded that stage, it ended all of that. All of those nerves that I had before the show, they were gone in the first few notes.”Kim from Cambridge“I just had this moment of heartbreak of, oh, he's not workshopping because there's nothing coming next.”Dave from Montreal“If he saw me, I wanted him to know that Dave from Montreal was staring back at him.”Dave from MontrealGuest information• Nicole from Winnipeg - Thunder Bay born and raised, Winnipeg for the last six years. Raised three daughters on The Hip, and two of them made the 2016 drive with her. Her husband plays in Retro Radio, a Winnipeg classic rock band, and their love story runs through this music.• Kim from Cambridge - 41 Hip shows, Kingston included, second row, in a shirt she made herself. Drove out in a new Jeep with her cousin, camping at Pancake Bay and Sleeping Giant on the way. Keeper of feathers, tour-suit leather patches, and a Six String Nation story.• Dave from Montreal - Montreal journalist. Seven shows on the Man Machine Poem Tour, 65 Hip shows deep by that August. Wrote a pre-tour love letter in the National Post and a Rover essay on cover bands. A book is on the way, and that is all he will say for now.• Alicia from Winnipeg - journalist and then-editor at Metro Winnipeg, who reviewed the show that night. On weekends she fronts Whoopsie Daisy, a Winnipeg classic rock cover band, where 'New Orleans Is Sinking' gets the rage out the healthy way.  https://whoopsiedacey.wordpress.com/Resources, links and references• setlist.fm - the full Winnipeg, August 5 2016 setlist, including both tour debuts.• David Bastedo - The Tragically Hip's official concert photographer. His Winnipeg crowd shot is the one Dave found himself inside.• Dave's pre-tour love letter in the National Post. https://nationalpost.com/entertainment/music/the-tragically-hip-gord-downie• Dave's Rover essay on cover bands, The Strictly Hip, and letting the music live on. https://therover.ca/searching-for-the-tragically-hip/• The bands keeping the music live, named on mic: Killer Whale Tank (Winnipeg), The Incredibly Hip (Brandon), The Hip Experience (on tour across Canada), The Strictly Hip (Buffalo), and Whoopsie Daisy.• "Secret Path" and The Downie Wenjack Fund - the work Nicole's daughter carries forward from the final tour.Calls to actionMeet us in Kingston. The Gathering runs August 20 to 23 - a mixer at the Merchant Pub, Choir! Choir! Choir! in Springer Market Square, a first listen of "The Tragically Hip Live, July 22 - August 20, 2016" the day it drops, a Long Time Running screening, and a farewell brunch at Morrison's on the way out of town. Get on the list. email jd@tthpods.comGEDfest comes to Toronto. October 17th, the anniversary of Gord's passing, at the Horseshoe Tavern with Grace, 2. Nine years running, over $750,000 raised, and this year it is for Campfire Circle and the Murphy Family Fund in Precision Medicine in Pancreatic Cancer. gedfest.caBuy jD a coffee. Editing four loquacious guests is a labour of love. Tips only, no guilt. So there's that. [hyperlink: Buy jD a coffee - buymeacoffee.com/tthtop40Related episodes• Yer Hipstories - Edmonton 2, July 30, 2016 https://kite.link/Edmonton2• Yer Hipstories - Victoria, July 22 2016 https://kite.link/Victoria• Now for Plan A - Redux https://kite.link/nowforplanaClosing paragraphNicole, thank you for the sixteen-hour round trip and for the image of a two-year-old singing 'Boots or Hearts' from a car seat. Kim, thank you for holding your nerve at that hotel bar until it turned into guitar picks. Dave, thank you for bringing your mom into the room with you, and for owning every emotion Gord taught you to own. Alicia, thank you for infinite stars out of five, the only rating system this series recognizes.The band takes an extra day off, then it is Ontario the rest of the way home. Come back on August 8th for London, August 8 2016 - new building, new panel, and the home stretch beginning. If you were in one of these rooms, leave yer Hipstory. This series is stitched together from them.Socials and community• Facebook: facebook.com/groups/tthpods• Instagram: @tthpods]• YouTube: youtube.com/@tthpods]• Email: jd@tthpods.com]#TheTragicallyHip #GordDownie #ManMachinePoem #FullyCompletely #RoadApples #NowForPlanASupport this podcast at — https://redcircle.com/tthtop40/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we delve into the intricate web of scientific advancements, regulatory updates, and strategic maneuvers shaping the industry. Let's begin with Eli Lilly's impressive financial performance, clocking a record-breaking $23 billion in revenue for Q2 2023. This achievement, driven by the success of Mounjaro and Zepbound in metabolic diseases, underscores the competitive landscape of therapies targeting chronic conditions. However, the slower launch of Foundayo highlights ongoing challenges. Meanwhile, competition in obesity treatments is intensifying as Novo Nordisk's Wegovy continues to dominate despite new entrants like Eli Lilly's Foundayo. This scenario reflects growing patient preference for oral medications over injectables. Gilead Sciences' HIV prevention franchise has exceeded $1 billion in quarterly sales, reflecting an increasing reliance on effective small molecule therapies for infectious diseases. Gilead also remains a focal point with its HIV pre-exposure prophylaxis franchise reaching sales milestones amid legal victories defending their tenofovir-based treatments. These legal precedents could influence future innovation policies across the industry. Artificial intelligence continues to make waves in drug discovery and clinical trials. Icon's partnership with Anthropic aims to integrate AI capabilities to accelerate drug development timelines. Similarly, Phylo and Chugai Pharmaceutical are collaborating to optimize drug discovery workflows using advanced AI platforms. These collaborations highlight a strategic move towards enhancing efficiency in drug development processes. In oncology, Amplia Therapeutics and Eli Lilly are evaluating a combination therapy for non-small cell lung cancer, while Evexta Bio and Roche are exploring a joint study for metastatic breast cancer. These partnerships underscore the industry's focus on combination therapies and precision medicine to improve cancer treatment outcomes. Additionally, AstraZeneca's partnership with CSPC Pharmaceutical to enhance biologics manufacturing in China signifies the importance of localized production capabilities. On the regulatory front, Arrowhead Pharmaceuticals' acquisition of an FDA rare pediatric disease priority review voucher for Plozasiran represents a commitment to addressing unmet needs in rare diseases. This voucher could expedite new drug applications, potentially bringing life-saving treatments to patients more quickly. Despite these advancements, challenges persist. Novo Nordisk's Cagrisema failed to achieve its primary endpoint in a Phase 3 trial for type 2 diabetes, highlighting the complexities of developing combination therapies for metabolic disorders. Similarly, Eli Lilly's discontinuation of its Phase 1/2 trial for GBA1 gene therapy reflects the hurdles faced in advancing gene therapies. Looking at industry dynamics, Amgen's decision to discontinue its early-stage obesity drug signifies a strategic shift towards focusing on more promising pipeline candidates like Maritide. This move aligns with broader trends prioritizing candidates with significant potential impact on patient care. Amgen's 'Repatha' is experiencing renewed interest due to positive cardiovascular risk reduction data, showcasing how robust clinical results can rejuvenate existing products. In regulatory news, Merck's 'Lipfendra' has been spotlighted by the FDA as part of its Complex New Product Validation pilot program. This positions Lipfendra as a potential game-changer in the PCSK9 inhibitor category. Lastly, financial maneuvers such as Attovia Therapeutics' $289 million IPO and Expedition Therapeutics' $115 million Series B funding highlight investor confidence in novel therapeutic areas like dermatological and respiratory treatments. The pharmaceutical landscape remains dynamic with Johnson & Johnson investing heavily in gene therapy ventures like Sail Biomedicines for CAR-T therapies. Meanwhile, regulatory challenges persist as seen with Capricor's cell therapy setback due to statistical complexities during FDA reviews. Despite setbacks faced by some companies, innovations continue to thrive. The launch of personalized genetic therapy centers signals a shift towards individualized medicine while research into safer CAR-T therapies progresses. In conclusion, these developments reflect an industry driven by innovation amidst regulatory challenges and strategic adjustments. As companies navigate this evolving landscape, their decisions will shape future healthcare innovations and patient care outcomes. Thank you for joining us on Pharma Daily; stay tuned for more insights from the world of pharmaceuticals and biotech.Support the show

Long before cancer survivors organized into a movement, Hollywood had already shaped how Americans understood the disease. Films rarely used the word “cancer,” physicians often withheld diagnoses from patients, and the people who survived were almost nowhere to be found on screen.Recorded before The Cancer Mavericks: A History of Survivorship became a documentary series, this bonus conversation explores where the project first began. Matthew Zachary sits down with his mother, Roz Greenzweig, a retired educator and lifelong film enthusiast whose memories of classic cinema became an unexpected lens for understanding how cancer was portrayed throughout the twentieth century.Together, they revisit landmark films including Dark Victory, Love Story, and other iconic portrayals that reflected an era when cancer was treated as unspeakable, inevitable, and almost always fatal. Their conversation contrasts those carefully constructed Hollywood narratives with the lived reality of a family confronting a brain cancer diagnosis in 1995, revealing how popular culture both reflected and reinforced the fears surrounding the disease.The discussion also foreshadows many of the themes explored throughout the documentary series: the evolution of patient advocacy, the emergence of cancer survivorship, the role of caregivers, and the power of storytelling to influence public understanding. Before policy changed, before advocacy organizations grew into national movements, conversations like these were already challenging long-held assumptions about what cancer looked like and who had the right to tell its story.Consider this the prologue to The Cancer Mavericks. Before the movement found its history, it began with a family trying to make sense of the stories they had inherited.RELATED LINKSAmerican Cancer Society⁠National Cancer Institute⁠American Film Institute⁠ER (NBC)⁠50/50 (Official)⁠Chasing Life (ABC Family Archive)⁠FEEDBACKLike this episode? Rate and review The Cancer Mavericks: A History of Survivorship on your favorite podcast platform. For more information, visit CancerMavericks.com. Questions? Email podcasts@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode, I sit down with Dr. Jennifer Timmons, MD, a board-certified family physician and longevity doctor, to explore why fertility cannot be separated from whole-body health. After more than a decade in traditional primary care at UCLA Health, Dr. Timmons recognized how often the conventional system waits for disease rather than addressing the dysfunction beneath it. She now blends functional, precision, and longevity medicine to help her patients build true vitality from the inside out. We talk about why your terrain matters as much as any protocol, how gut health quietly drives inflammation and autoimmune conditions, and why so many seemingly unrelated symptoms trace back to a compromised gut lining. Dr. Timmons walks us through the role of leaky gut in fertility, the importance of blood sugar stability for egg and sperm quality, and the everyday lifestyle inputs that influence cellular health, including light exposure, circadian rhythm, time-restricted eating, and microplastic exposure. She also shares which longevity practices are accessible to everyone, why social connection turned out to be one of the strongest predictors of long life in Harvard research, and the simple food order and movement habits that move the needle most for metabolic health. This conversation is a thoughtful, grounded look at how to support the body so it can do what it already knows how to do. Key Takeaways: Fertility is a reflection of whole-body health, not an isolated system. Optimizing your terrain matters as much as any procedure or protocol. Gut health is foundational. Leaky gut and compromised intestinal lining can drive autoimmune conditions, inflammation, and impaired nutrient absorption, all of which affect fertility outcomes. Even a nutrient-rich diet cannot do its work if the gut barrier is inflamed. Healing the gut lining is often the missing piece in fertility preparation. Chronic inflammation is one of the biggest drivers of disease and reproductive dysfunction. Identifying and addressing inflammatory triggers can shift the entire picture. Blood sugar stability directly impacts egg and sperm quality. Simple shifts like eating fiber and protein before carbs, walking after meals, and avoiding late-night eating make a real difference. Light, circadian rhythm, and meal timing are powerful regulators of hormonal and cellular health. A simple 12-hour overnight fast offers measurable benefits without extreme restriction. Microplastics and environmental toxins are quietly impacting reproductive health. Fiber, NAC, sweating, and reducing plastic exposure all support your body's natural detox pathways. Longevity practices are accessible to everyone. Whole foods, movement, quality sleep, clean water, and strong social connection are the real foundations of a long, healthy life. Social connection is one of the strongest predictors of longevity, even more than diet or socioeconomic status in Harvard research. Community is medicine. Guest Bio: Dr. Jennifer Timmons, MD is a Longevity Physician and the Founder and Medical Director of Timmons Wellness, a concierge medical practice providing hyper-personalized healthcare. With over 10 years of experience practicing traditional primary care at UCLA Health, along with advanced training in Functional and Integrative Medicine, Precision Medicine, and Longevity Medicine, Dr. Timmons is committed to helping people enjoy longer, healthier lives through a customized care model. Her expertise includes hormone optimization, metabolic and cardiovascular health, proactive disease prevention, weight management, and more, encompassing both proven strategies and innovative technologies. As Founder and Medical Director of Timmons Wellness, she helps people move beyond basic wellness toward longevity medicine, and build sustainable habits that increase not just the years of their lives, but their number of healthy years. Website: TimmonsWellnessMD.com Instagram, TikTok, YouTube: @JenniferTimmonsMD Disclaimer: The information shared on this podcast is for educational and informational purposes only and is not intended as medical advice. Please consult with your healthcare provider before making any changes to your health or fertility care. Ready to discover what your body needs most on your fertility journey? Take the personalized quiz inside The Wholesome Fertility Journey and get tailored resources to meet you exactly where you are:  https://www.michelleoravitz.com/the-wholesome-fertility-journey For more about my work and offerings, visit: www.michelleoravitz.com Curious about ancient wisdom for fertility? Grab my book The Way of Fertility: https://www.michelleoravitz.com/thewayoffertility Join the Wholesome Fertility Facebook Group for free resources & community support: https://www.facebook.com/groups/2149554308396504/ Connect with me on social: Instagram: @thewholesomelotusfertilityFacebook: The Wholesome Lotus

Precision Hormone Health: Testosterone, Menopause, Muscle, Sleep, and Proactive Longevity: Endocrinologist Dr. Florence Comite details her book “Invincible: Defy Your Genetic Destiny to Live Better, Longer” and her precision-medicine approach to proactive longevity. She discusses testosterone decline beginning in the 30s in both sexes, stress-related low T (including in special forces), and testosterone's roles in energy, cognition, motivation, muscle, bone, and chronic disease risk. Comite argues genes are a “draft” and health destiny can be altered through epigenetic-like choices, individualized data, and early monitoring. For women, she emphasizes estrogen, progesterone, and testosterone in perimenopause/menopause, preferring bioidentical hormones and criticizing WHI's use of Premarin/Provera and older participants. She covers osteoporosis prevention, muscle as an “organ of longevity,” protein intake, resistance training, continuous glucose monitors for individualized diet, sleep quality tracking via wearables, and selective use of DHEA, pregnenolone, growth hormone pathways, and peptides with attention to sourcing and risk.

The band took their bow. The house lights came up, and nobody in the Saddledome moved. This is the night the ovation would not stop.Episode summaryAugust 3rd, 2016. A Wednesday. Two nights after the first Calgary show, The Tragically Hip walked back into the Scotiabank Saddledome and played the city goodbye. Ten years on, three fans who were in the building pass the night around the table with jD.Spencer from Calgary is back from the night one episode. This was his third show of the Man Machine Poem Tour and the last time he saw the band live, and he spent it with Alan and Chantel, old friends from ten years of Hitmen games and Saddledome nights. His friend Al's text said it best: heavy but celebratory, like we all knew what was happening but we chose to live in the moment.Julie from Calgary hadn't seen The Hip since 1997. The tickets were a first date anniversary present. She and Keith from Calgary went with her parents, still dating, married the next year, and 'Ahead by a Century' was the wedding song.They talk about the word glioblastoma and where it landed in Julie's family. About Spencer's Periscope vigil in a Calgary bar the night the tour opened in Victoria. About 'Scared' with the lights up, the Jaws shirt, and an ovation that went on so long Gord Downie just stood there in the house lights, telling Calgary it was beautiful.Nobody here claims to be the expert. They were in the room, and ten years later two of them run a charity festival because of it. That part comes up too.Key takeaways• The tickets were a first date anniversary present. Keith and Julie were still dating at the show, married the next year, and 'Ahead by a Century' was their wedding song. Spencer had it at his wedding too.• Spencer watched the Victoria opener through a stranger's Periscope stream in a Calgary bar, and only breathed again once Gord got through the first song.• The middle of the set was an "In Violet Light" collector's run: 'Use It Up' (first since 2006), 'It's a Good Life If You Don't Weaken' (tour debut), 'Throwing Off Glass' (first since 2009), and 'The Dire Wolf' (tour debut). Verified against setlist.fm, cross-referenced with Hipbase.• Julie marks 'Scared' as the moment the night turned - lights up, arms around strangers, the first cracks showing.• The morning the news broke, Keith wore The Hip under his suit to client meetings at the bank, and decided anyone put off by it was not his kind of client anyway.• GEDfest exists because of this show. Julie and Keith founded it after the tour, it turns nine this year, and Spencer signed on as an ambassador before the episode was over.Quotes"Everyone just became one. And for one night, there's very few nights in your life where everybody is connected, positive, happy, loving, sad. You could have hugged anyone in there. You could have kissed anyone in there. It would have been accepted."- Julie from Calgary"This might sound like hyperbole, but in a lot of ways that show changed my life."- Keith from CalgaryGuest information• Spencer from Calgary - back from night one. Three shows on the final tour, and this was the last time he saw The Hip live. His daughter's name is Grace. Draw your own conclusions.• Julie from Calgary - GEDfest co-founder. Had not seen The Hip since 1997. Her first podcast, ever. She did great.• Keith from Calgary - GEDfest co-founder. Still has the paper tickets. The poster is framed on the wall.Resources, links and references• setlist.fm - the full Calgary, August 3 2016 setlist, including both tour debuts and the ten year gap on 'Use It Up'. • Hipbase - primary source for The Tragically Hip setlists and discography, cross-referenced against setlist.fm. • GEDfest - live music for the life and legacy of Gord Edgar Downie, with proceeds to cancer charities across Canada. gedfest.ca]• Helping Families Handle Cancer - the Calgary charity Spencer's sister runs for families whose child is going through cancer.• Lilliput Hats - Karyn Ruiz's Toronto shop, where the hats Keith remembers came from. Related past episodes:• Yer Hipstories: Reflections From The Final Tour - Vancover Night 1 https://kite.link/Vancouver1. • Yer Hipstories: Reflections From The Final Tour - Victoria, July 22 2016 - the opening night Spencer watched through a stranger's phone. https://kite.link/Victoria• Fully & Completely: redux - Man Machine Poem - the record behind the four song block.https://kite.link/MMPreduxThings to knowGive the anniversary somewhere to go. GEDfest plays Toronto for the first time - Saturday, October 17th, the anniversary of Gord's passing, at the Horseshoe Tavern with Grace, 2. Every dollar raised goes to Campfire Circle and the Murphy Family Fund in Precision Medicine in Pancreatic Cancer. Julie and Keith built this festival out of the night you just heard about. Tickets are on sale now. So there's that. [hyperlink: Grab tickets - GEDfest.caCome home to Kingston. The Gathering runs August 20th to 23rd - a mixer at the Merchant Pub, Choir! Choir! Choir! in Springer Market Square, a listening party, a Long Time Running screening, and a farewell brunch at Morrison's. If you're making the trip, get on the list. [hyperlink: Email jd@tthpods.com]Buy jD a coffeeEditing is hard. Help keep the battery charged and buy jD a coffee. Tips only, no guilt. [hyperlink: Buy jD a coffee - buymeacoffee.com/tthtop40Closing paragraphJulie, thank you for doing your first podcast ever and for the bubble of love. Keith, thank you for the postcard: the whole dome on its feet, lights up, nobody leaving. Spencer, thank you for coming back, and for signing up as a GEDfest ambassador live on mic. That is how this community works. In a couple of days the tour crosses the Rockies - Winnipeg, August 5 2016, with a brand new panel. The Tragically Hip Podcast Series keeps heading east, all the way home.Socials and community• Facebook: facebook.com/groups/tthpods• Instagram: @tthpods• YouTube: youtube.com/@tthpods• Email: jd@tthpods.com#TheTragicallyHip #GordDownie #GordonEdgarDownie #ManMachinePoem #InVioletLight #HipFansSupport this podcast at — https://redcircle.com/tthtop40/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Longevity expert Dr Florence Comite joins me to explain why testosterone, not estrogen, drives body composition and ageing in midlife women. Decline isn't inevitable - it's programmable. She unpacks why testosterone (which women carry in larger amounts than estrogen) drives muscle, visceral fat and brain fog from your 30s on, why only a third of us should fast, and the five biomarkers - fasting glucose, HbA1c, fasting insulin, cholesterol risk ratio and free testosterone - that predict where your healthspan is headed and how to change it. WHAT YOU'LL LEARN Why women carry more circulating testosterone than estrogen, and what its decline does to muscle, visceral fat and cognition from your 30s What "I don't feel like myself anymore" is actually signalling beneath the surface How cortisol quietly drives the anxiety-out-of-nowhere, the 2am wake-ups and the stubborn weight around your middle Why only a third of women should fast, and the 3-hour glucose test that tells you which third you're in What the five non-negotiable biomarkers reveal about where your healthspan is headed TIMESTAMPS 00:00 Intro: Why You Don't Feel Like Yourself After 35 - Peak Health, Testosterone Decline & the 30s Shift 05:52 - Perimenopause, Cortisol & Anxiety Out of Nowhere: Belly Fat, Sleep and the Caregiver Load 13:28 - Wearables, CGM & the Fasting Third/Third/Third: Measuring How Your Body Really Ages 20:11 - Who Should Actually Fast: The 3-Hour Glucose Test, Protein at Every Meal & the Oatmeal Trap 27:00 - Testosterone for Body Composition & Energy: UK Access, the 2024 Study & Protein for Muscle 33:46 - The 5 Biomarkers That Predict How You Age - Plus the 7 Patterns of Health Decline 39:37 - Decade by Decade for Women vs Men: Bone Loss, Osteoporosis, Andropause & Owning Your Healthspan VALUABLE RESOURCES - Invincible (Dr Comite's new book): https://www.penguin.co.uk/books/475986/invincible-by-comite-florence/9781529977066  - Dr Florence Comite's website: https://www.comitemd.com/  - Follow Dr Comite on Instagram: https://www.instagram.com/drflorencecomite/  AlgaeCal Plus*‡: Science-backed supplements designed to support healthy aging

Dr. Anil Bajnath joins the show to discuss the future of integrative medicine, artificial intelligence, multi-omics, and how personalized healthcare is transforming the way clinicians identify and treat chronic disease. Together, we explore why moving beyond symptom management to uncover root causes is essential for improving patient outcomes and advancing the next generation of medicine.We dive into:What precision medicine really means and why it's reshaping healthcareHow AI can enhance clinical decision-making without replacing the clinicianThe role of multi-omics in identifying the root causes of chronic illnessEnvironmental toxins, lifestyle factors, and other hidden drivers of diseaseWhy biomarkers and personalized data are the foundation of preventive medicinePharmacogenomics and tailoring treatments to each individual's unique biologyThe concept of your "biological 401(k)" and investing in long-term healthspanWhy clinicians need to embrace systems biology and pattern recognitionThe future of precision health education and preparing providers for the next era of medicinePractical ways patients and practitioners can begin applying precision medicine today

Rebecca Bloom is a former employee benefits and executive compensation attorney who spent more than 25 years helping women navigate cancer, work, insurance, disability coverage, and financial survival. She is the founder and author of When Women Get Sick, a book built from decades inside the legal, workplace, and patient advocacy systems most people only discover after diagnosis.Bloom started in Big Law at Simpson Thacher handling employee benefits and compensation work she originally chose to pay off student loans. Then her mother was diagnosed with breast cancer. Suddenly the language she used in corporate law offices became the language of survival at home. Explanation of benefits forms. Coverage disputes. Second opinions. Disability protections. Medical leave. Bills no one could explain.That collision changed the direction of her life.In this episode, Bloom explains how serious illness quietly turns patients into unpaid administrators managing paperwork, logistics, financial risk, and emotional labor while trying to survive treatment. She breaks down how employer based health insurance shapes nearly every aspect of cancer care in America and why women often carry the invisible burden of protecting everyone else from discomfort while they themselves fall apart.The conversation digs into workplace power, the illusion of the healthcare “safety net,” caregiver exhaustion, and the class divide hiding underneath patient empowerment culture. Bloom explains why educated, insured women with resources still struggle to navigate healthcare bureaucracy and what happens to patients without those advantages.This episode explores cancer care, health insurance, employee benefits, patient advocacy, workplace protections, caregiving, and the structural incentives that force sick people to become project managers of their own survival.RELATED LINKSRebecca BloomWhen Women Get SickBay Area Cancer ConnectionsSimpson Thacher & BartlettFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship email podcasts@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Should you go natural or conventional? Dr. Pai explains how to combine treatments based on labs, cancer type, and risk—plus avoid unnecessary therapies. #IntegrativeOncology #CancerCare #SmartMedicine

Synopsis: In an industry often defined by rapid innovation and high-stakes science, long-term success in biotech requires more than breakthrough discoveries—it demands strategic clarity, resilient leadership, and a deep understanding of unmet patient needs. In this engaging conversation, Rahul Chaturvedi sits down with Robert Jacks, President & CEO of Sparrow Pharmaceuticals, to explore his unconventional journey from civil engineering to biotech leadership, the lessons learned from building and exiting successful companies, and why creating lasting value should take precedence over chasing acquisitions. Robert reflects on his career spanning Pfizer, entrepreneurship, venture capital at OrbiMed, and leading multiple biotech companies, sharing how his experiences shaped his approach to leadership, capital allocation, and company building. He explains why influence matters more than authority, how empathy creates stronger organizations, and why keeping biotech companies lean allows them to remain resilient throughout unpredictable funding cycles. The conversation then explores Sparrow Pharmaceuticals' evolution from a rare disease company into a precision medicine leader focused on difficult-to-control type 2 diabetes. Robert provides an in-depth look at the emerging science behind cortisol biology, HSD1 inhibition, and why excess intracellular cortisol may represent one of the industry's most overlooked drivers of metabolic disease. He also discusses Sparrow's recent clinical data, the rationale behind its strategic pivot, the future of patient stratification in cardiometabolic disease, and how Sparrow aims to complement—not compete with—the rapidly expanding GLP-1 landscape. From fundraising and leadership philosophy to clinical development strategy and the next frontier of precision medicine, this episode offers practical insights for biotech founders, investors, and industry leaders navigating the complexities of building enduring biotech companies. Biography: Robert has 25 years of experience in the biopharmaceutical industry. He has founded or co-founded multiple companies and raised more than $300 million. Previously, Robert was the President & CEO of Indalo Therapeutics, a clinical-stage biotechnology company developing therapeutics for serious fibrotic diseases, and President, CFO, and Co-Founder of Symbiomix Therapeutics, which was sold after achieving NDA approval for Solosec®. Robert also previously held the positions of Head of Corporate Development for Tobira Therapeutics, Head of Business Development for ACT Biotech, and Entrepreneur-in-Residence for OrbiMed Advisors. Robert began his pharmaceutical industry career in finance and product development at Pfizer, where he last worked as the Director of Business Development for Oncology and Infectious Diseases. Robert earned an MBA from Columbia Business School, an MSE in Civil Engineering from Stanford University, and a BSE in Civil Engineering from Duke University. When not solving intractable healthcare problems, Robert spends as much time as possible with his two daughters.

Vasanta Pundarika built her career inside healthcare investment banking before launching Lotuspring, an advisory firm focused on women's health and behavioral health. She spent nearly 20 years advising healthcare systems, treatment providers, and growth stage companies on mergers, financing, and operational strategy while watching the industry repeatedly misunderstand the people it claimed to serve.The conversation starts unexpectedly with anthropology, bread, and language. Vasanta explains how she spent years changing the pronunciation of her own name to make other people comfortable before eventually reclaiming it. That thread opens into a much larger discussion about adaptation, identity, and what institutions quietly train people to tolerate.From there, the discussion moves into behavioral health, women delaying care, and the invisible labor that healthcare business models routinely ignore. During COVID, Vasanta noticed men's behavioral health units refilled faster than women's units. The reason had nothing to do with demand. Women were still home managing caregiving responsibilities, children, aging parents, and households while their own mental health collapsed in the background.The episode examines what happens when healthcare companies become “snazzy big brands” before building real clinical substance underneath. Vasanta describes the tension between mission and margin inside healthcare startups, private equity backed care models, and behavioral health expansion. The conversation pushes on who benefits when healthcare scales aggressively, who absorbs the operational pressure, and how patient trust erodes long before executives notice it on a dashboard.They also discuss patient advocacy culture, anthropology as systems analysis, healthcare capitalism, prior authorization, investor language, and why some clinically excellent companies never survive long enough to scale.RELATED LINKSVasanta PundarikaLotuspringWomen's Health HorizonsSakhi for South Asian SurvivorsNACDPrinceton University Anthropology DepartmentFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship email podcasts@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if AI could help clinicians move beyond detection and make breast cancer treatment more precise and personalized? In this episode of Entrepreneur Rx, host John Shufeldt sits down with Stacey Stevens, CEO of SimBioSys, to discuss her career in medical technology, healthcare AI, women's health, and precision oncology. Stacey shares how her experience at Philips Healthcare, iCAD, and her own women's health advisory company shaped her path to leading SimBioSys. The conversation explores Stacey's early work helping bring some of the first AI tools in breast imaging to market, the long road to healthcare adoption, and why clinical evidence, trust, reimbursement, and enterprise-grade security all matter when selling AI into healthcare. Stacey also explains how SimBioSys is taking AI beyond breast cancer detection and applying it to treatment planning. The company's platform uses breast MRI data to create interactive 3D visual models of the breast and tumor, helping surgical oncologists better understand tumor location, volume, and whether a patient may be eligible for breast-conserving surgery. John and Stacey also discuss SimBioSys' next frontier: using image-based AI to help assess a patient's risk of breast cancer recurrence and support more personalized treatment decisions. Beyond the technology, the episode covers startup leadership, fundraising, the realities of building in regulated healthcare, and why trust, transparency, and patient impact must come first. About Stacey Stevens: Stacey Stevens is the CEO of SimBioSys and a healthcare technology executive with deep experience in medical imaging, AI, women's health, commercialization, fundraising, and strategic growth. Before joining SimBioSys, she held leadership roles at Philips Healthcare and iCAD, where she helped introduce early AI technologies in breast imaging. She also founded Ellevate, a women's health strategic advisory company focused on accelerating the adoption of meaningful scientific breakthroughs in women's health. About SimBioSys: SimBioSys is developing a precision medicine platform initially focused on breast cancer, with technology designed to support clinicians and patients across the cancer care journey. Its platform uses AI and spatial biophysics to turn breast MRI data into interactive 3D visual models that can support surgical planning, treatment decisions, and more personalized cancer care. About Xcellerant Ventures: Xcellerant Ventures is a venture capital firm that invests in innovative companies across healthcare, technology, defense, and other emerging industries. Through multiple funds and investment vehicles, including the Jetstream Venture Fund ($5,000 minimum interval fund), the firm partners with visionary founders, provides strategic guidance, and helps connect investors with opportunities in the private markets. Its portfolio includes companies developing solutions that have the potential to transform industries and improve lives.

Biochemist Suzanne Pfeffer is an expert on the molecular roots of Parkinson's disease. Her work focuses on mutated proteins linked to Parkinson's risk. She's discovered, for instance, that drugs inhibiting one of the proteins can help neurons regrow primary cilia and stave off cell death, reversing disease progression. Since similar drugs are in clinical trials, her findings bring great hope for people with a subtype of Parkinson's and hopefully can be linked to earlier detection through warning signs like REM sleep disruptions and loss of smell. “This is precision medicine,” Pfeffer tells host Russ Altman of the future of Parkinson's disease on this episode of Stanford Engineering's The Future of Everything podcast. Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu. Episode Reference Links: Stanford Profile: Suzanne Pfeffer Connect With Us: Episode Transcripts >>> The Future of Everything Website Connect with Russ >>> Threads / Bluesky / Mastodon Connect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / Facebook Chapters: (00:00:00) Introduction Russ Altman introduces guest Suzanne Pfeffer, a professor of biochemistry at Stanford University. (00:03:25) Path into Parkinson's Research How Pfeffer's protein work led to a life-changing work on Parkinson's disease. (00:05:28) Parkinson's Primer The various causes and the effects of the disease on the brain and body. (00:10:26) Lewy Bodies and Dementia How Lewy bodies, synuclein, and dementia relate to Parkinson's disease. (00:11:56) Molecular Trafficking Pfeffer breaks down the effects of LRRK2 and GBA mutations in the brain. (00:16:10) Early Disease Changes Some of the early changes in the body and how they show up as symptomatically. (00:20:04) Current Treatments The limitations of symptom-focused treatments. (00:21:46) Treating Earlier Opportunities for slowing or reversing disease progression when detected earlier. (00:22:32) Targeting LRRK2 Current research on disease treatment & trial challenges. (00:27:33) The Value of Basic Science Why curiosity-driven research can unexpectedly lead to disease breakthroughs. (00:29:33) Future In a Minute Rapid-fire Q&A: biomarkers, brain donation, and better Parkinson's treatments. (00:31:52) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Hey friends, Chase here. Every summer, I revisit conversations from the archive that have stood the test of time. Not because I'm nostalgic, but because the best ideas don't expire. They deepen. This is another installment of Summer School—episodes I go back to when I'm stuck, looking for the person in my network who's already lived the answer. This one with Tony Robbins is a perfect example. I've been navigating some peak performance challenges around my physical body—joints breaking down from a life as an athlete. Tony has spent years deep in the breakthroughs happening in precision medicine and regenerative health. I originally brought him on the show to learn what was possible. I'm bringing the conversation back for Summer School because those questions matter even more now. Tony is a legend: #1 New York Times bestselling author, life and business strategist, entrepreneur, philanthropist, and peak performance expert. He's coached world-class athletes, entertainers, Fortune 500 CEOs, and U.S. presidents. He's also a friend. I've been front row at his multi-day seminars. I've used his techniques—from mental training to visualization to priming—and yes, I've walked on fire with him. But this conversation goes beyond mindset. It goes into the habits that separate people who are successful and fulfilled… and into Life Force, Tony's book on the regenerative medicine breakthroughs that can transform the quality of your life—and the lives of the people you love. "Success without fulfillment is the ultimate failure." — Tony Robbins Summer School: Tony Robbins on Peak Performance, Precision Medicine, and Transforming Your Quality of Life Tony's obsession is a simple question with a lifelong answer: what actually changes the quality of people's lives? He frames the work as pattern recognition, pattern utilization, and pattern creation—learning from the best so you don't waste 10 or 20 years figuring it out the hard way. Then standing on those shoulders long enough to create your own. That lens shows up everywhere in this episode: in habits, in health, and in mindset. After being told some of his own health challenges were irreversible, Tony experienced firsthand how regenerative technology didn't just help him heal—it made him stronger. And the bigger point he makes is that these breakthroughs aren't reserved for the ultra-wealthy. As technology doubles in power and halves in cost, access keeps expanding. Medicine isn't the whole story, though. Tony also deconstructs the patterns of top performers—because your habits and your mindset still determine whether any of it matters. What You'll Hear in This Episode Why Tony does this work—and how growing up with pain made him obsessed with helping people reclaim themselves The habits of people who are both successful and fulfilled, starting with a mission bigger than yourself Why progress equals happiness, and why comfort quietly kills growth How to prime your day on purpose: cold water, gratitude, three-to-thrive, sincere compliments, and doing the hardest thing first The personal story behind Life Force—family illness, a pituitary tumor, a torn rotator cuff, spinal stenosis, and the stem cell turning point What's changing in regenerative medicine: stem cells, gene editing, diagnostics, sleep science, and more How to use Life Force as a guidebook, not a 600-page homework assignment Why mindset still decides the outcome—including the surprising power of belief, placebos, and your "emotional home" Patterns of Peak Performance One of the most useful parts of this conversation is how concrete it gets. Identifying patterns that already work for peak performers can save years of trial and error. In this episode, three keep coming up: 1. Have a mission Have something you care about more than yourself. It could be your family, your craft, your business, your community—anything real. Tony's blunt about this: when people have something more important than themselves, they don't run out of energy or excitement. When it's only about you, comfort creeps in. And comfort is where growth dies. His one-word formula for happiness is the same one he's taught for decades: progress. If you're not making progress, you're not growing. And if you're not growing, you're not giving. Growing and giving is the game. 2. Prime with gratitude Most people assume their thoughts are simply "their thoughts." Tony's point is that your thoughts are primed by your environment—so you might as well prime yourself on purpose. His morning starts with cold water (not because he loves it, but because it trains the brain: when I say go, we go). Then a 10-minute priming practice built around gratitude, a prayer-type focus, and "three to thrive"—three outcomes he sees and feels as already done. Why gratitude? Because you can't be grateful and angry at the same time. You can't be grateful and fearful at the same time. Most people, as he puts it, have a highway to stress and a dirt road to happiness. Priming is how you reverse that wiring. He also leaves someone a sincere audio compliment each day—not generic praise, but something specific that deepens the relationship. You can learn his free priming process at tonyrobbins.com/priming. 3. Do the hardest thing first Difficult work needs your best energy. Tony's rule is simple: crush the hardest thing early, create momentum, and let everything else get easier. How you start and end your day both matter. Of the two, he says starting well may matter most—because it frames everything that follows. Timecodes So You Can Jump Around 00:00 – Welcome and why this episode is part of Summer School 04:23 – Tony Robbins joins the show 05:03 – What gets Tony up in the morning: impact, reclaiming yourself, and pattern recognition 11:37 – Habits of the most successful and fulfilled people 13:16 – Progress equals happiness; growing and giving as the game 14:44 – Priming your day: cold plunge, gratitude, three-to-thrive, hardest thing first 20:35 – Why Tony wrote Life Force—and the personal experiences behind it 22:21 – The cancer story that shifted him from victimhood to biohacking 25:20 – Pituitary tumor diagnosis, second opinions, and learning to question standard answers 28:53 – Snowboard crash, torn rotator cuff, spinal stenosis—and the stem cell turning point 31:37 – Regenerative medicine breakthroughs worth knowing 38:54 – How to approach Life Force as a guidebook 43:19 – Access and cost: why these tools aren't only for the wealthy 47:00 – Mindset, placebos, and upgrading your emotional home 52:38 – Closing thoughts Why This Conversation Still Matters It's easy to treat health, energy, and longevity as tomorrow's problem—something you'll deal with when you have more time, more money, or a clearer diagnosis. This conversation makes that delay harder to justify. Tony's point isn't that you need every breakthrough tomorrow. It's that ignorance isn't bliss. Ignorance is pain. And in the worst cases, it's preventable loss. The diagnostic tools alone—especially if you're 40 or older—can change the trajectory of a life before a crisis shows up. At the same time, he keeps bringing it back to something simpler and more immediate: how you start your day, what you care about more than yourself, and whether you're actually making progress. The regenerative medicine is extraordinary. The habits and mindset are what make any of it usable. That's why this episode earned a Summer School seat. The science has only accelerated since we first recorded it. The human part—fulfillment, discipline, belief—hasn't gotten any less essential. Keep Going Deeper If this conversation resonates: Life Force: How New Breakthroughs in Precision Medicine Can Transform the Quality of Your Life & Those You Love — Tony's guidebook to regenerative medicine, diagnostics, and the mindset that makes healing possible. (100% of profits are donated to feed people in need and fund research on Alzheimer's, cancer, and heart disease.) Free priming practice: tonyrobbins.com/priming Follow Tony: Instagram | X/Twitter | Website Questions to Reflect On What do I care about more than myself—and is that mission actually driving my days? Where have I confused success with fulfillment? Am I priming my mornings on purpose, or being primed by accident? What's the hardest thing I keep delaying—and what would change if I did it first? Am I waiting for a health crisis before I get curious about prevention, diagnostics, or recovery? Where has "I don't have access" become a story that keeps me from doing the homework? What 3–5 things could I do right now—habits, sleep, diagnostics, mindset—to raise the quality of my life and protect the people I love? The Core Idea Peak performance isn't just about grinding harder. It's about recognizing the patterns that create an extraordinary life—then using them, and eventually creating your own. Your body is part of that equation. So is your mind. So is having something you care about enough that you refuse to get comfortable. Tony's invitation is simple and demanding: don't wait until you're forced to pay attention. Learn what's available. Prime your days on purpose. Grow. Give. And don't let an old story about what's "possible for people like me" keep you from tools that could change—or even save—a life. If there's one lesson worth carrying forward from this Summer School session, it's this: Success without fulfillment is the ultimate failure—and progress, in body and mind, is still the most reliable path to both.

Discussion Highlights: the importance of precision medicine as the intersection of biology, lifestyle, and environment, influenced by both genetic predispositions and external factors the complexity of choosing appropriate tests and the need for expertise in interpreting results the gap between standard laboratory testing and deeper molecular analysis needed for precision health the need to equip doctors with tools to interpret multi-omic data as AI becomes more prevalent in healthcare the concept of a "biological 401(k)" to describe the daily deposits and withdrawals of bioenergetic currency, including diet, exercise, sleep, nutrition, meaning, purpose, and environment, which contribute to overall health resilience the importance of understanding and addressing root causes of health issues rather than just treating symptoms Dr. Anil Bajnath is the Founder & President of the American Board of Precision Medicine, author of The Longevity Equation, and a board-certified physician specializing in precision and longevity medicine. His clinical practice is built around root-cause resolution, translating genetics, advanced biomarker analysis, and individualized nutrition into frameworks real people can use. He's known for helping patients and practitioners turn complex data into practical action and lasting lifestyle change. Learn more at ifho.org and follow Dr. Bajnath on Instagram @dranilbajnath Visit ConfidenceThroughHealth.com to find discounts to some of our favorite products.Follow me via All In Health and Wellness on Facebook or Instagram.Find my books on Amazon: No More Sugar Coating: Finding Your Happiness in a Crowded World and Confidence Through Health: Live the Healthy Lifestyle God DesignedProduction credit: Social Media Cowboys

Brad Power spent years advising major corporations on systems design, process engineering, and decision making before lymphoma shoved him into the patient side of American healthcare. Instead of accepting the experience at face value, he started reverse engineering the machinery around cancer itself. Brad is the founder of Cancer Patient Lab and Open Cancer AI, two projects built around a blunt reality most patients discover too late: the healthcare system rewards people who know how to navigate it. Everyone else risks getting steamrolled by information asymmetry, insurance barriers, administrative friction, and institutional incentives designed around efficiency instead of human survival.The conversation starts with Harvard Business Review and Tumblr blogs before moving directly into the darker architecture underneath modern cancer care. Power explains how hospitals optimize for throughput, how insurance companies reward operational consistency over personalized medicine, and why many patients quietly end up needing a crash course in oncology, reimbursement policy, and behavioral psychology while fighting for their lives.The discussion digs into CAR-T therapy, functional testing, AI assisted decision support, and the growing collision between personalized medicine and standardized care pathways. Power argues that engaged patients often get better outcomes because they learn how to push for off guideline treatments, contest denials, and ask smarter questions. The counterpoint lands hard: patients should never have needed to become experts in the first place.The episode also explores the cultural consequences of AI entering cancer care. OpenAI advertising, data privacy, trust erosion, pharmaceutical influence, and “agentic AI” all collide inside a healthcare economy already drowning in distrust. Power sees artificial intelligence as a force multiplier for patient literacy and access. The larger system still decides who gets approved, who gets delayed, and who gets left behind.By the end, the conversation lands exactly where modern healthcare keeps forcing people to land: survival increasingly depends on learning how the machine works before the machine works on you.RELATED LINKSBrad PowerCancer Patient LabOpen Cancer AIHarvard Business ReviewResearch to the PeopleCAR T Cell TherapyFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship email podcasts@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

A cutting-edge technology and an exciting recent hire hint at exciting developments in the future of precision medicine in the diagnosis and treatment of Alzheimer's disease.

By the time the paper hit version 71, Dr. Nirosha Murugan had already done the hard part. The data were real. The experiment had worked. A team of researchers had used a wearable bioreactor to trigger limb regeneration in frogs, a result with obvious implications for regenerative medicine. But the science still wasn't getting over the line. The problem wasn't the work. It was the translation.On this episode of Standard Deviation, host Oliver Bogler talks with Dr. Nirosha Murugan, a biophysicist and Tier II Canada Research Chair in Tissue Biophysics at Wilfrid Laurier University, about what happens when a scientist working at the edges of quantum biology, bioelectricity, and tissue regeneration runs headfirst into the unwritten rules of academic publishing. Murugan's research asks biologists to think beyond molecules and chemistry alone, and to consider the physical signals, electromagnetic fields, and invisible forces that shape development and healing. It is ambitious science. It is also exactly the kind of work that can make gatekeepers nervous.Bogler follows Murugan through the less glamorous part of discovery: the hidden curriculum of getting a paper published, securing scientific credibility, and learning that data do not simply “speak for themselves.” Murugan describes how jargon buried the pitch of her own work, how a lack of editorial support left her at a disadvantage, and how the JEDI program at the Life Science Editors Foundation paired her with a former journal editor who taught her how to structure a manuscript, write a cover letter, and survive peer review.The result was publication in Science Advances, but the larger story is about power. Who gets taught the rules of biomedical research. Who has access to grant writers, editors, and institutional polish. Who is left to brute-force their way through the maze. And how one scientist, having finally found the map, now makes sure her own trainees do not have to learn it the hard way.RELATED LINKSDr. Nirosha Murugan⁠Wilfrid Laurier University⁠Life Science Editors Foundation⁠JEDI Program⁠Science Advances paper on limb regeneration⁠FEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship email podcasts@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode, Richard Barakat, MD, Physician-in-chief & Executive Director at Northwell Health Cancer Institute, discusses expanding access to advanced cancer therapies, integrating AI into oncology care, and driving the future of precision medicine. He also shares insights on improving efficiency, survivorship care, and clinical trial access for all patients.

Dr. Jess Peatross trained in conventional medicine and worked as a hospitalist before she started questioning why so many chronically ill patients kept getting worse inside the healthcare system she trusted. Her perspective carries weight because she spent years following every protocol exactly as taught before walking away from hospital medicine entirely.Raised in Huntington, West Virginia during the opioid crisis, she entered medicine believing the system existed to heal people. Instead, she found hospitals driven by billing codes, liability management, and pharmaceutical dependence while patients with chronic illness, autoimmune disease, mold exposure, and chronic pain cycled endlessly through appointments and prescriptions.Dr. Peatross explains what pushed her toward functional medicine, cannabis therapy, and prevention focused care after watching patients improve only after leaving conventional treatment pipelines behind. The conversation tackles physician burnout, chronic illness stigma, healthcare incentives, and the growing collapse of trust between patients and institutions.The discussion also moves into supplements, environmental toxins, ultra processed food, and the uncomfortable economics behind keeping people permanently sick but continuously billable. Dr. Peatross describes the professional backlash that comes with challenging medical orthodoxy while Matthew connects her experience to the broader erosion of public trust across American healthcare.Together they unpack what happens when patients stop believing the system can help them and start searching elsewhere for answers.RELATED LINKSDr. Jess PeatrossInstagramMarshall UniversityBrave New WeedFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship email podcasts@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.