Brain Channel (Audio)

Alzheimer's disease is a major health crisis that is projected to become an even larger threat in the coming decades. According to the National Institute on Aging, the number of Americans 65 and older with Alzheimer's could rise from 5.8 million in 2020 to 13.8 million by 2050. Given the severity of this health crisis and the toll it takes on patients, their families and society, we must be prepared today to address the needs of tomorrow. Dean Frank LaFerla of UC Irvine's School of Biological Sciences presents an overview of the state of Alzheimer's disease research. Following his presentation, the panel discusses emerging trends in research, care and the upcoming challenges we will face and how we might mitigate them. [Health and Medicine] [Show ID: 38660]

Thomas C. Südhof, M.D., Stanford University, discusses facets of the fundamental cell biology of ApoE and APP analyzed in stem cell-derived human neurons. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38405]

Dr. Songi Han, professor in the Department of Chemistry, Biochemistry and Chemical Engineering at UC Santa Barbara, talks about her research into the function of proteins in the body and how changes like protein Tau tangles can lead to neurological diseases like Alzheimer's. Series: "GRIT Talks" [Health and Medicine] [Science] [Show ID: 37869]

The COVID-19 pandemic has resulted in unprecedented changes in routines across the globe. For individuals with autism (ASD) changes in routine can have a direct impact on behavioral symptoms. Doris Trauner, MD examines the effect the pandemic has had on children with moderate to severe autism. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 37654]

Constance Smith-Hicks, MD, PhD provides an overview of the sensory challenges in autism spectrum disorder and explains how the sensory system develops. Learn about the somatosensory system as well as current treatments. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 37653]

What is the prevalence of epilepsy in individuals with autism? Brian Moseley, MD explores the connection and influencing factors. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 37660]

How can the principles of precision medicine apply to autism? Elizabeth Torres, PhD, shares how it has shaped her research. She also explains the three contemporary revolutions in science that have impacted research - neuroscience, genomics, and wearables. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 37659]

How can employers and universities better support individuals with autism? A panel of experts including parents, employers, and researchers discusses the support programs that currently exist and what needs to change to make sure neurodiverse people are successful in the world of work and in post-secondary education. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 37655]

Dhakshin Ramanathan, MD, PhD, explains the basics of neuroscience and how brain stimulation works. He takes a deep dive into Transcranial Magnetic Stimulation (TMS) noting how it works, why it works, and its efficacy as a treatment. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 37609]

Tarek Rajji, MD, shares research from current trials combining brain stimulation with interventions including cognitive remediation. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 37598]

What is magnetic brain stimulation and how can it be used to improve our health? Dhakshin Ramanathan, MD, PhD, and Zafiris "Jeff" Daskalakis, MD, PhD, join Jyoti Mishra, PhD, to discuss how and why to use therapies such as TMS and MTS to treat depression. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 37597]

Can virtual classes help seniors with fall prevention and staying fit? What are the impacts of diet on inflammation and mental health? Jeanne Nichols, PhD, and Mark Rapaport, MD, detail their respective work in mental and physical well-being. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 37593]

Dr. Georges Naasan discusses communication difficulties associated with the language syndrome of Alzheimer's Disease. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 37334]

Dr. Georges Naasan describes the symptoms seen in the frontal/executive syndrome of Alzheimer's disease. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 37335]

Neural imaging is a useful technique to understand the biological basis of artistic creativity. Post-doctoral Scholar Karen Chan Barrett explores how researchers measure the creative brain in real time noting that improvisation is a rich model for studying the neural connections of creativity. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 37148]

Research suggests that listening to or singing songs can provide emotional and behavioral benefits for people with Alzheimer's disease. Dr. Theresa Allison provides an overview of music in the context of dementia and caregiving relationships. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 37150]

Mark Tuszynski, MD, PhD, Bob Yant, and Lawrence S.B. Goldstein, PhD discuss the newest research and treatments for spinal cord injury, including how neural stem cells may be leveraged to potentially regain function. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37102]

Discover how experts in cell biology are partnering with a pioneer in imaging technology to develop a personalized approach to treating Parkinson’s disease. Series: "Innovations Shaping the Future of Parkinson's Disease Treatment " [Health and Medicine] [Show ID: 37040]

Hear directly from the team that developed the groundbreaking ability to make new, healthy neurons that can replace those lost in Parkinson’s disease and their vision to turn their discovery into a life-changing therapy. Series: "Innovations Shaping the Future of Parkinson's Disease Treatment " [Health and Medicine] [Show ID: 37041]

Learn how social workers and a patient advocate are partnering to develop a suite of free support programs and services for Parkinson's disease patients and their care partners in San Diego. Series: "Innovations Shaping the Future of Parkinson's Disease Treatment " [Health and Medicine] [Show ID: 37038]

Hear how a team of interdisciplinary experts solved the structure of LRRK2, a gene found to be mutated in Parkinson’s disease, and how their discovery is guiding the way for new targeted therapeutics. Series: "Innovations Shaping the Future of Parkinson's Disease Treatment " [Health and Medicine] [Show ID: 37039]

Irene Litvan, MD Joseph Wang, MD explain how experts are collaborating across disciplines to adapt wearable technology to automate medication management, offering a greater quality of life for individuals with Parkinson’s disease. Series: "Innovations Shaping the Future of Parkinson's Disease Treatment " [Health and Medicine] [Show ID: 37037]

Robert L Hendren, DO, Professor of Psychiatry and Behavioral Science discusses how to build resilience in children with or at risk of neurodevelopmental disorders through innovative biomedical and resilience enhancing interventions. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 36870]

Researchers are exploring the exciting possibility that electrical stimulation of nerve cells of brain and spinal cord could aid in tumor resections, monitor epilepsy, bypass spinal cord injury to cure paralysis, as well as treat other diseases of the nervous system and beyond. Bioelectronic neuromodulation devices are evolving as the gold standard and are projected to impact the lives of millions of people. At UC San Diego, collaborations across engineering and medicine aim to bring the latest technological advances to patient care. Shadi Dayeh, Professor, Department of Electrical and Computer Engineering, UC San Diego, covers the development and clinical translation of UCSD’s multi-thousand channel microelectrode arrays to map the human brain and spinal cord. The talk will provide a perspective on global efforts in neuromodulation devices and summarize lessons learned in the technological, medical, and regulatory fronts. Series: "Exploring Ethics" [Health and Medicine] [Science] [Show ID: 36819]

Stem cell research is changing the way Alzheimer's disease is diagnosed and treated. Larry Goldstein, PhD and Doug Galasko, MD join Alysson Muotri, PhD to share the latest findings and what the future may hold. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36805]

As a neurologist, Robert Knight has seen what happens when the brain crashes around violently inside the skull. And he’s aware of the often tragic consequences. Throughout his 40 years as an academic researcher and medical doctor, the University of California, Berkeley, professor of psychology and neuroscience has known students and friends whose lives and careers were derailed by head injuries from bicycle and car crashes. He’s held in his hands brains destroyed by accidental blows to the head. Not surprisingly, he cringes when he imagines his young grandchildren falling off a bike and hitting their heads. So, Knight invented a better helmet — one with more effective padding to dampen the effects of a direct hit, but more importantly, an innovative outer shell that rotates to absorb twisting forces that today’s helmets don’t protect against. Series: "UC Berkeley News" [Health and Medicine] [Science] [Show ID: 36761]

This presentation explores the role of radiotherapy in the management of central nervous system (CNS) tumors and the possible neurological complications of radiotherapy. Dr. Steve Baunstein also discusses the techniques to improve the therapeutic ratio in CNS radiotherapy. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 36507]

Lawrence S.B. Goldstein, PhD discusses his career in science and his work to understand the molecular basis of neuronal defects in Alzheimer's Disease. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36338]

Stem cell research is providing hope for new therapies to treat neurodegenerative diseases. Hear from those on the front lines about what is next. Moderated by Clive Svendsen, PhD, Cedars-Sinai HD Care: Patient Support Perspective Ralph Kern MD MHSc, Brainstorm Cell Therapeutics: NurOwn (autologous MSC-NTF cells) in ALS- phase 3 clinical trial update Jeanne F. Loring, PhD, Aspen Neuroscience: Neuron replacement therapy for Parkinsons disease Leslie Thompson, PhD, UCI: Stem Cell Based Therapy for Huntington's Disease Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36323]

Jeanne F. Loring, PhD Aspen Neuroscience Series: "Women in Science" [Health and Medicine] [Science] [Show ID: 36321]

Kevin Petrecca, MD, PhD, FRCS(C) presents his paper as published in the July 8, 2020 issue of Nature. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36173]

Ralph Kern MD MHSc Brainstorm Cell Therapeutics Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36320]

Leslie Thompson, PhD UCI Series: "Women in Science" [Health and Medicine] [Science] [Professional Medical Education] [Show ID: 36322]

Researcher Alysson Muotri is using stem cells to study everything from autism to the Zika virus. In this excerpt Muotri discusses stem cell and brain organoid research for possible applications to human diseases. Series: "Health Matters" [Health and Medicine] [Show ID: 36301]

Xiang Dong Fu, PhD shares the findings of his paper published in the June 24, 2020 issue of Nature. By investigating a strategy to directly convert astrocytes to dopaminergic (DA) neurons in the substantia nigra, the research shows a potentially powerful and clinically feasible approach to treating neurodegeneration by replacing lost neurons. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36179]

Irene Litvan, MD; Don Cleveland, PhD; and David Higgins, PhD, discuss the next generation of treatments for Parkinson's Disease and offer a patient's perspective in this conversation on the cutting edge stem cell research. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36076]

Interactive immune systems are at the center of cancer and other diseases. Dr. Matthew Krummel explores some lesser-known functions of the immune system related to memory making, arteriosclerosis, and gut health. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 36205]

Dr. Aimee Kao discusses key behaviors known to protect brain health. Dr. Kao looks at population trends and wonders if they tell a complete story. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 36154]

Dr. Michael Wilson is a neurologist who specializes in infectious and autoimmune syndromes of the central nervous system. These include inflammatory conditions, such as meningitis, encephalitis and myelitis. In this talk he looks at new treatments being developed. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 35926]

In times of stress, anxiety, and isolation finding effective strategies to understand our emotions and how we relate to the world at large often brings comfort. Mindfulness, meditation, and compassion have long been championed as helpful strategies but how do they impact our well being, if at all? Fadel Zeidan joins William Mobley to discuss his work applying scientific methods to these practices to quantify and discover how and why they work. Series: "Brain Channel" [Show ID: 35824]

What are the origins of hearing? What is the evolutionary benefit of music? And why do we get chills when we listen to certain songs? This episode of UCLA's LiveWell podcast features UCLA neuropsychology expert Bob Bilder about the neuroscience behind music and its benefit for our health and wellness. Series: "LiveWell" [Show ID: 35623]

How wisdom is defined and measured in the laboratory, the biology of wisdom, its dynamic relationship with culture, wisdom and aging, wisdom and health, and how we might build wiser societies. THis animation is based on "The New Science of Practical Wisdom" published by Johns Hopkins University Press in the journal Perspectives in Biology and Medicine. Series: "Stein Institute for Research on Aging" [Show ID: 35488]