Podcasts about cancer stem cells

Subscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsStem cell therapy is transforming regenerative medicine, offering powerful treatments for chronic inflammation, aging, autism, and more. In this eye-opening interview, triple board-certified physician Dr. Joy Kong reveals how stem cells work, why they're more than just anti-aging tools, and how DNA and energy-based healing could be the future of healthcare.You'll learn how IV stem cell therapy works, how to avoid dangerous clinics, and why stem cells are revolutionizing treatment for autoimmune conditions, mental health, and skin and hair rejuvenation. Dr. Kong also shares her journey from psychiatry to founding the American Academy of Integrative Cell Therapy.This episode covers the powerful regenerative potential of stem cells, the rise of IV therapy, how to avoid unregulated clinics, and why true healing must always be holistic. Whether you're seeking answers for chronic illness or curious about the future of longevity, this is a must-watch.Connect further to Hol+ at https://holplus.co/- Don't forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.About Dr. Joy Kong:Dr. Joy Kong is a triple board-certified anti-aging physician and stem cell specialist, renowned for her expertise in stem cell therapy and commitment to educating both physicians and the public. With a strong presence in the industry, she has established herself as a trusted voice through her extensive lecturing at national and international conferences, as well as her publications in scientific journals.As a dedicated educator and pioneer in the field of regenerative medicine, Dr. Kong has founded the American Academy of Integrative Cell Therapy (AAICT) and trained numerous physicians from around the world. Her innovative approach has also led to the creation of Chara Health USA and Chara Biologics, premier companies providing cutting-edge products and services to patients across the United States. With numerous accolades, including Stem Cell Doctor of the Year and Stem Cell Doctor of the Decade, Dr. Kong continues to be a respected figure in the medical community, dedicated to advancing the field of regenerative medicine and improving patient outcomes through her emphasis on scientific data, passion, authenticity, and integrity.Her inspiring memoir, "Tiger of Beijing," which recounts her remarkable journey as an immigrant from China at the age of 20 starting with her visa rejection in 1991, was named 2020 Book of the Year by IAOTP.Stay ConnectedSubscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsFollow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Join the conversation on X: https://x.com/@drtazmdTikTok: https://www.tiktok.com/@drtazmdFacebook: https://www.facebook.com/drtazmd/Follow Dr. Kong on Instagram:https://www.instagram.com/dr_joy_kong/Host & Production TeamHost: Dr. Taz; Produced by Rainbow Creative (Executive Producer: Matthew Jones; Lead Producer: Lauren Feighan; Editors: Jeremiah Schultz and Patrick Edwards)Don't forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+01:58 - Dr. Joy Kong's Journey into Regenerative Medicine  03:30 - Stem Cell Therapy for Autism and Chronic Conditions  05:15 - Inside the American Academy of Integrative Cell Therapy  08:14 - Stem Cells as Energy and DNA-Based Healing  12:31 - How Stem Cells Navigate the Body and Target Inflammation  16:36 - Umbilical vs. Fat-Derived Stem Cells: Safety and Sourcing  20:53 - Avoiding Stem Cell Scams: Testing, Regulations, and Red Flags  26:53 - IV Stem Cell Therapy: Benefits, Applications, and Costs  43:24 - Stem Cells for Skin, Hair Loss, and Anti-Aging Results

In this episode of the Spectrum of Health podcast, Dr. Christine Schaffner shares key insights from her recent presentations at leading health conferences. She explores the growing recognition of mast cell activation as a major health issue and highlights the innovative role of peptides and exosomes in treatment. Dr. Schaffner also discusses the significance of addressing cancer stem cells and the deeper root causes behind mast cell activation, offering a forward-thinking perspective on healing and clinical care. For the full show notes please visit my website: https://www.drchristineschaffner.com/Episode286  

Mirko Beljanski, PhD, was a pioneering molecular biologist who discovered natural solutions for fighting cancer and targeting cancer stem cells. His groundbreaking research into non-toxic, plant-based therapies challenged conventional treatments, leading to the sabotage by French authorities in 1996. Despite the controversy, his work demonstrated how specific botanical extracts, such as Pao Pereira and Rauwolfia […]

- Interview with Sylvie Beljanski and Upcoming Conference (0:00) - Interviews with Brilliant Guests and Breaking News (2:19) - Critique of Modern Medicine and AI (5:09) - Special Report on AI and Human Behavior (19:50) - Book Review: "Immoderate Greatness" by William Ophuls (20:33) - Special Report: Trump's Betrayal and War with Iran (29:36) - Book Review: "Collapse" by Jared Diamond (50:18) - Customer Appreciation Week at Health Ranger Store (58:37) - Interview with Sylvie Beljanski Continues (1:08:06) - Research on Cancer Stem Cells and Future Plans (1:20:50) - Background and Personal Stories (1:27:43) - Addressing the Root Causes of Cancer (1:29:47) - Living Cancer-Free in a Toxic Environment (1:31:42) - Lifestyle Choices and Personal Experiences (1:34:01) - Hope for Regulatory Change (1:35:49) - The Psychological War on Cancer (1:37:55) - Financial Conflicts of Interest in Cancer Treatment (1:43:50) - The Role of Prevention and Lifestyle Choices (1:45:55) - The Impact of Toxic Substances on Health (1:51:01) - Conclusion and Final Thoughts (1:52:34) For more updates, visit: http://www.brighteon.com/channel/hrreport NaturalNews videos would not be possible without you, as always we remain passionately dedicated to our mission of educating people all over the world on the subject of natural healing remedies and personal liberty (food freedom, medical freedom, the freedom of speech, etc.). Together, we're helping create a better world, with more honest food labeling, reduced chemical contamination, the avoidance of toxic heavy metals and vastly increased scientific transparency. ▶️ Every dollar you spend at the Health Ranger Store goes toward helping us achieve important science and content goals for humanity: https://www.healthrangerstore.com/ ▶️ Sign Up For Our Newsletter: https://www.naturalnews.com/Readerregistration.html ▶️ Brighteon: https://www.brighteon.com/channels/hrreport ▶️ Join Our Social Network: https://brighteon.social/@HealthRanger ▶️ Check In Stock Products at: https://PrepWithMike.com

What if everything we thought we knew about cancer was wrong? For decades, scientists have debated what really causes cancer. Is it genetic mutations, as the Somatic Mutation Theory suggests? Is it a metabolic dysfunction, as the Metabolic Theory argues? Or is there a deeper, overlooked truth—one that could redefine cancer treatment as we know it? In this episode, Dr. Ralph Moss and Ben Moss break down the battle between competing cancer theories, why conventional wisdom is being challenged, and what the latest research is uncovering about cancer stem cells, metabolism, and the Warburg Effect.

In this episode of the Dr. Jockers Functional Nutrition Podcast, Dr. Jockers and Dr. Kevin Conners discuss the root causes of cancer, focusing on how toxins like pesticides and mycotoxins disrupt cellular function. They highlight the importance of detoxification and immune support in effective cancer treatment.   Dr. Conners introduces frequency medicine as a cancer treatment, explaining how Rife machines target cancer cells at specific frequencies to enhance immune recognition and destruction. He emphasizes integrating this method with other therapies for a comprehensive treatment plan.   Listeners will gain insights into holistic cancer treatment strategies, including detoxification, immune system stimulation, and addressing individual cancer causes. Dr. Conners shares his extensive experience and the multifaceted approach necessary for optimal patient outcomes.   In This Episode: 00:00 Understanding Cancer: The Basics 03:27 Interview with Dr. Conners: Natural Strategies for Cancer 03:52 The Root Causes of Cancer 05:45 The Role of Toxins and Detoxification 06:28 Functional Medicine Testing and Mycotoxins 08:09 Cancer as an Adaptive Physiological Process 11:17 Frequency Medicine and Cancer Treatment 20:21 Nutritional Approaches and Fasting 27:58 Cancer Stem Cells and Circulating Tumor Cells 37:42 Final Thoughts and Words of Inspiration   This podcast is sponsored by ShopC60.com. C60 is a powerful, Nobel Prize-winning antioxidant, that helps to optimize mitochondrial function, fights inflammation, and neutralizes toxic free radicals! I'm a big fan of using C60 in conjunction with your keto and intermittent fasting lifestyle to support your immune system, help your body detox, and increase energy and mental clarity. My favorite C60 products for Keto & IF lifestyles include C60 Purple Power in Organic MCT Coconut Oil (you can add this to your coffee) and their delicious Sugar-Free C60 Gummies (made with allulose and monk fruit)! If you are over the age of 40, and you'd like to kick fatigue and brain fog to the curb this year, visit shopc60.com and use the coupon code “JOCKERS” for 15% OFF  and start taking back control over your health today!   Have you heard of Paleovalley's amazing Turmeric Complex? It contains whole food and organic turmeric instead of just isolated curcumin.    And we know that organic turmeric is way better, and one of the best things you can take to shut down inflammation in the body and support healthy blood flow and blood pressure.    It also includes coconut oil and black pepper as its ingredients, which has been shown to improve the absorption of turmeric by 2000%! Plus, there's also organic ginger, rosemary, and cloves which synergize with the turmeric to help improve digestion and blood sugar.   Paleovalley's Turmeric Complex also supports joint health, mental clarity, and improved brain function. You've just got to try this product. Visit paleovalley.com/jockers!     “Fasting can make chemotherapy more effective by starving the cancer cells and reducing side effects.” -Dr. Kevin Conners     Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean  TuneIn Radio   Resources: Visit https://shopc60.com/jockers – Use code “JOCKERS” to get 15% off! Paleovalley's Turmeric Complex - visit paleovalley.com/jockers     Connect with Dr. Kevin Conners: Website - https://www.connersclinic.com/   Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/   If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/  

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Work to cure breast cancer is an important field. Ramneet Kaur, assistant professor of biology at Columbus State University, details new ideas in this fight. I am a cell and molecular biologist with cancer biology as my research area. I have a Ph.D. in Biotechnology and a post-doc in cancer biology from Harvard Medical School, […]

About This Episode Dr. Paul Anderson, based in Seattle, shares transformative insights on holistic approaches to cancer.  He emphasizes clean eating's pivotal role in cancer prevention, treatment strategies based on cancer stages, and highlights the importance of monitoring cancer stem cells (CSCs). Diving deep into IV Vitamin C treatment, Anderson notes its unique capability to harm cancer cells while supporting healthy ones.  Furthermore, he discusses the rapidly evolving landscape of Circulating Tumor Cell Tests and their significance in monitoring cancer.  For those navigating the cancer journey or seeking holistic health insights, this interview offers a wealth of knowledge. Dive into the summary or watch/listen for comprehensive understanding. Resources Mentioned: Dr. Paul Anderson's Website "Outside the Box Cancer Therapies" (book) Tests: RGCC CellSearch Biocept Maintrac IvyGene High dose, concentrated mushroom extracts Exogenous ketones Vitamin B3 Nicotinamide riboside Detailed Summary Introduction by Ryan: Dr. Anderson was Ryan's son's naturopathic oncologist. Ryan appreciated Dr. Anderson's vast knowledge and ability to answer difficult questions. Dr. Paul Anderson's Introduction and Background: Based in Seattle, Washington. Met Ryan during the treatment of Ryan's son, Ryder. His practice is divided into two equal parts: Treating patients with cancer, including children (which is uncommon). Treating individuals with complicated chronic illnesses unrelated to cancer. Teaches doctors and emphasizes on sharing knowledge. Co-authored the book "Outside the Box Cancer Therapy" with Dr. Stangler. Working on another book focusing on the emotional aspects and process of being diagnosed with cancer. Comparison between Naturopathic Oncologists and Integrative Medical Doctors: Dr. Anderson emphasizes practical experience, learning from patients. He offers specialized treatments, including IV therapy, hyperbaric oxygen, hyperthermia therapies, etc. Naturopathic oncologists and integrative MDs can both be limited in their treatments by the hospitals or systems they work in. Discussion on IV Vitamin C Treatment: Dr. Anderson is recognized internationally for his expertise on this topic. Benefits can be gained from both low and high doses of IV vitamin C, depending on the application. The amount needed can vary based on body weight and the specific health of the patient. High doses can range from 50-100 grams for most adult-sized individuals. Vitamin C remains in the system for about 24 hours post-IV. Vitamin C is unique in that it harms cancer cells while supporting healthy cells. Lower doses (around 10-15 grams) can provide significant improvements in quality of life for frail or end-of-life patients. Circulating Tumor Cell Tests: Have improved over time; past versions like RGCC and CellSearch were not as accurate. Technology is rapidly changing and affecting the reliability of these tests. Biocept, Maintrac, and IVY gene are currently used tests. These tests are especially useful for: Monitoring cancer in remission or no evidence of disease. Tracking the effectiveness of ongoing treatments. Treatment Strategies Based on Cancer Stage: Late Stage: Urgency in treatment is crucial. Need a holistic approach, addressing dietary habits, toxins, infections, hormones, and overall health. Aim to grab the cancer's attention and slow its progression. Early Stage: There's more flexibility in treatment approaches. Focus can be on non-cancer issues like detoxifying, balancing hormones, improving gut health, and addressing mental health. Treatment options can include concentrated mushroom extracts, metabolic treatments like exogenous ketones, or even dietary shifts such as raw vegan diets. Post-Cancer Treatment: Post chemotherapy and radiation, there's an increased risk for secondary cancers because they can stimulate cancer stem cells. Importance of recovery after initial treatments and secondary prevention to ensure recurrence doesn't occur. Repairing the body and suppressing cancer stem cells is essential. Diet's Impact on Cancer: No single "best" diet for cancer elimination; however, diet plays a pivotal role. Emphasis on clean eating: Avoid processed foods, chemicals, pesticides, and herbicides. A shift in diet can have a noticeable effect on cancer within 1-3 months. Key Dietary Recommendations: Intermittent Fasting (IF): IF for even 13 hours has shown to reduce the recurrence of breast cancer. It activates autophagy (cell cleaning) and has other metabolic benefits. Diet Cleanliness: Remove junk and chemicals from diet. Plant-based Spectrum: High in polyphenols, fiber, dense nutrients, and low in simple carbs. Raw food diets can quickly get the body's attention. Ketogenic Spectrum: Shifts body metabolism and may be beneficial against certain types of cancers. It's crucial to balance protein intake since excess protein can be converted into sugar. Modified Mediterranean Diet: High plant-based with clean protein and fat sources, minimal grains. Diet Adaptability: Initial diet is about getting the body's attention; it might differ from the long-term diet. Both ketogenic and raw food diets have shown positive effects on patients with various cancer types. Adapt the diet based on what a person can do and tolerate. Long-term success requires consistency in dietary habits. Observational Cases: Noted a patient surviving stage 3/4 breast cancer for over 15 years primarily using a ketogenic diet. Other cases showed success with a raw food diet transitioned into a modified vegetarian diet. Regular Monitoring: Emphasizes tracking certain blood work indicators (e.g., LDH, alkaline phosphatase, GGT) regularly. These markers can provide insights into inflammation, oxygen levels, and overall body health. Monitoring helps catch subtle shifts in the body's health, guiding adjustments in treatments and dietary habits. Cancer Stem Cells (CSCs) Insights: CSCs are smarter than regular tumor cells (daughter cells). While treatments like chemotherapy or radiation can reduce tumor size, they might make one prone to relapses because CSCs hide and wait. Many people have dormant CSCs in their bodies. The challenge is to keep these cells inactive. CSCs can recruit normal cells to become cancerous. CSC Triggers & Management: One major trigger for CSCs is inflammation. Inflammation sources include lack of exercise, poor diet, toxins, infections. Healthier lifestyles, such as better diets and regular exercise, produce anti-cancer metabolic triggers. Intermittent fasting and periodic longer fasts can slow CSC activity. Diet, detox, and addressing specific toxic exposures can help maintain an environment less favorable for CSC growth. NAD Therapy Insights: NAD is essential for energy production in mitochondria. High doses of NAD can be problematic for those with cancer because some cancers can utilize excess NAD for growth. For those with a cancer history, lower dose NAD therapy can be considered safe. In active cancer cases, high-dose NAD therapy should be avoided. Oral supplementation with nicotinamide riboside can help, but high doses may pose risks. Resources and Contacts: Book recommendation: "Outside the Box Cancer Therapies" provides practical insights into cancer treatments. Dr. Paul Anderson's clinic: Advanced Medical Therapies, located in Seattle, Washington. ***Get every full two hour call in Going Integrative Plus and ask your questions live directly to the top integrative cancer doctors in the world!***  

For years, I have warned women who are told they are "cancer-free" about breast cancer stem cells. These are the "baby cancer cells" responsible for the recurrence and spread of breast cancer.  This is why I sat down with Nathan Crane—a natural health researcher and certified holistic cancer coach. He is an award-winning author, inspirational speaker, Amazon's #1 bestselling author, and 20x award-winning documentary filmmaker. I trust his insight on breast cancer stem cells, and so do the world's leading experts at the  “Winning the War on Cancer: The Beljanski Integrative Cancer Conference (I'm also speaking, and you can use my code: “ICC1023DRV” for 10% off!) While chemo and radiation treatments are critical for healing in certain cases, they actually do NOT kill the breast cancer stem cells. This fact must be more widely acted on, as untreated stem cells often lead to recurrence. Tune in to learn the latest research and how to act strategically. For our listeners, Nathan has gifted access to his e-book, Becoming Cancer Free. ____________________________ Here are some highlights from this Podcast: Breast Cancer Stem Cells: Understanding the significance of breast cancer stem cells is crucial for preventing recurrence. These are rogue cells that conventional treatments often miss, leading to potential relapse. Importance of Targeting Stem Cells: Treating breast cancer must go beyond removing tumors. Targeting cancer stem cells is essential since they can give rise to new tumors and cancers if not addressed. The Beljanski Foundation: The Beljanski Foundation conducts scientific research into natural solutions for cancer, focusing on plants with mechanisms to inhibit and eliminate cancer stem cells. Mirko Beljanski's Legacy: The foundation's work is inspired by Mirko Beljanski, who faced government opposition for his cancer research. His legacy lives on through his daughter Sylvie Beljanski, who continues his mission to find natural cures. Integrative Cancer Conference: The Integrative Cancer Conference in Jacksonville, Florida, is a fundraising event hosted by Nathan Crane and the Beljanski Foundation. It aims to raise funds for breast cancer stem cell research and share cutting-edge breakthroughs in holistic and natural cancer treatment. Empowerment Through Knowledge: Understanding breast cancer stem cells removes fear of recurrence and provides hope. Integrative approaches, including specific plant extracts, aim to target and eliminate these cells, leading to more effective prevention and treatment strategies.

Does cancer discriminate based on race? Then, can stem cells be used to repair diseased hearts? And finally… Light exercise may be beneficial for concussion recovery. Learn More: https://radiohealthjournal.org/medical-notes-death-rates-from-recurring-cancer-stem-cells-fix-bad-hearts-exercising-after-a-concussion Learn more about your ad choices. Visit podcastchoices.com/adchoices

Discover the power of an integrative approach to cancer treatment on the latest episode of the Integrative Cancer Solutions podcast with Dr. Karlfeldt. This informative podcast focuses on the need for alternative cancer treatments and invites listeners to learn about powerful integrative and holistic methods that may help fight cancer. Dr. Karlfeldt shares his personal experience of losing his father to colon cancer, which led him to focus on cancer prevention and healing. From discussing the limitations of conventional oncology to the importance of finding an oncologist who educates and involves patients in the healing process, this podcast covers it all. Learn about cutting-edge cancer therapies like photodynamic therapy and the use of anti-inflammatory and antioxidant therapies to support overall health and wellness. Tune in to discover the importance of maintaining healthy habits, adopting a positive mindset, and asking how cancer can serve as a tool for growth and self-improvement. Don't miss out on this powerful episode. Listen now to Integrative Cancer Solutions with Dr. Karlfeldt.- Integrative cancer solutions- Dr. Karlfeldt's personal experience- Naturopathic oncology- Limitations of conventional oncology- Empowering the patient- Addressing cancer from various angles- Maintaining healthy habits- Cancer as a wake-up call- Understanding cancer stem cells- Combining traditional and terrain therapies- Calming cancer stem cell activation- Photodynamic therapy- Education and prevention- Comprehensive and integrative approach- The Karlfeldt Center - Live consultation with cancer patient next week KEY POINTS[0:0:32] Astonishingly, integrative and holistic approaches to cancer treatment have been shown to drastically improve survival rates and save lives.[0:6:48] By taking a holistic approach to treating cancer, Naturopathic Oncology has been proven to dramatically improve patient outcomes - not just physically, but emotionally and spiritually too![0:7:19] By shifting your mindset from "why is this happening to me" to "how can this challenge serve me," you can unlock a world of powerful possibilities and experience growth, healing, and profound appreciation.[0:9:36] Cancer is a devastating, multifaceted disease that demands comprehensive and expert treatment for the best chance of success.[0:14:38] Cancer can be seen as a powerful catalyst that inspires individuals to re-examine and transform their mental, spiritual, and physical health.[0:17:47] Surgery can cause cancer to spread more aggressively due to the disruption of tumor coordination and the activation of cancer stem cells - a potentially life-threatening consequence. To minimize this risk and ensure a healthier recovery, pre-surgery treatments that address the body as a whole are essential.[0:19:25] Cancer stem cells, which can resist traditional treatments, have the potential to spark tumor initiation and growth - making anti-inflammatory and antioxidant strategies paramount for minimizing their activation and fighting cancer.[0:24:9] Experience the power of natural remedies with PolyMVA, curcumin, vitamin C, ozone, and laser therapy – scientifically proven to reduce inflammation and invigorate stem cell activity![0:27:32] PDT is revolutionizing cancer treatment with its awe-inspiring ability to eradicate cancer cells and bolster the body's natural defense system using only the power of light![0:30:0] Utilizing innovative photodynamic therapy and stem cells/exosome-like vesicles, new breakthroughs in cancer treatment are being achieved, drastically increasing the efficacy of photosensitizers to effectively target and destroy tumors.[0:31:27] By combining photodynamic therapy with hyperbaric oxygen therapy, patients can experience powerful oxidation benefits, dramatically increasing the oxygen content in their tissue.[0:33:47] Consistently engaging in healthy habits can significantly reduce the risk of cancer recurrence, whereas a lapse in diet and exercise can have detrimental effects.Integrative Cancer Solutions was created to instill hope and empowerment. Other people have been where you are right now and have already done the research for you. Listen to their stories and journeys and apply what they learned to achieve similar outcomes as they have, cancer remission and an even more fullness of life than before the diagnosis. Guests will discuss what therapies, supplements, and practitioners they relied on to beat cancer. Once diagnosed, time is of the essence. This podcast will dramatically reduce your learning curve as you search for your own solution to cancer. For more information about products and services discussed in this podcast, please visit www.integrativecancersolutions.com. To learn more about the cutting-edge integrative cancer therapies Dr. Karlfeldt offer at his center, please visit www.TheKarlfeldtCenter.com.

We’d love to hear from you (feedback@breakingbadscience.com)Look us up on social media Facebook: https://www.facebook.com/groups/385282925919540Instagram: https://www.instagram.com/breakingbadsciencepodcast/Website: http://www.breakingbadscience.com/Patreon: https://www.patreon.com/breakingbadscienceStem cells are a mysterious cellular construct with some pretty unique properties. Properties which have led to intense discussions about life, aging, cancer, the nature of disease itself, and even religion.  But what are they? Why was the discovery of these cells so important? Why are they so controversial and how has that controversy affected research in the last few decades? Join hosts Shanti and Danny as we discuss stem cells, the confusion surrounding them, and why the controversy is not only important but necessary in this episode of Breaking Bad Science. ReferencesPlatt, A.; A Brief History of U.S. Stem Cell Policy. Research America. 2020. https://www.researchamerica.org/advocacy-action/issues-researchamerica-advocates/stem-cell-research/brief-history-us-stem-cellHwang, N., et. al.; Controlled Differentiation of Stem Cells. Advanced Drug Delivery Reviews. 11-Oct-2007. 60:2 (199 - 214). Doi: https://doi.org/10.1016/j.addr.2007.08.036Robinton, D., Daley, G.; The Promise of Induced Pluripotent Stem Cells in Research and Therapy. Nature. 18-Jan-2012. 481 (295 - 305). Doi: https://doi.org/10.1038/nature10761Chin, M., et. al.; Induced Pluripotent Stem Cells and Embryonic Stem Cells are Distinguished by Gene Expression Signatures. Cell - Stem Cell. 2-Jul-2009. 5:1 (111 - 123). Doi: https://doi.org/10.1016/j.stem.2009.06.008Biehl, J., Russell, B.; Introduction to Stem Cell Therapy. Journal of Cardiovascular Nursing. Mar/Apr-2009. 24:2 (98 - 105). Doi: https://doi.org/10.1097/JCN.0b013e318197a6a5Ayala, F.; Cloning Humans? Biological, Ethical, and Social Considerations. PNAS. 21-Jul-2015. 112:29 (8879 - 8886). Doi: https://doi.org/10.1073/pnas.1501798112Hernandez, D.; 500 Years Later, da Vinci’s Mechanical Lion is Brought to Life. Popular Mechanic. 19-Sep-2019. https://www.popularmechanics.com/technology/a29020685/leonardo-da-vinci-mechanical-lion-display/Ayob, A., Ramasamy, T.; Cancer Stem Cells as Key Drivers of Tumour Progression. Journal of Biomedical Science. 06-Mar-2018. 25:20. Doi: https://doi.org/10.1186/s12929-018-0426-4Kim, K.S.; Converting Human Skin Cells to Neurons: A New Tool to Study and Treat Brain Disorders? Cell - Stem Cell. 2-Sep-2011. 9:3 (179 - 181). Doi: https://doi.org/10.1016/j.stem.2011.08.004Support the show (https://www.patreon.com/breakingbadscience?fan_landing=true)

Dr. John Dick is known internationally for his discovery of blood stem cells. His work has broadened understanding of where and why leukemia starts, and what we could do to prevent it. In this episode of Behind the Breakthrough, Dr. John Dick takes us behind the scenes on his career, building on the pioneering work of Drs. James Till and Ernest McCulloch—the first to define the properties of stem cells. He delves into the pivotal moments that led to discoveries that have changed the face of cancer research, and why science doesn’t happen in a vacuum.Read more at www.behindthebreakthrough.ca. 

Oncotarget recently published "CD44+/EPCAM+ cells detect a subpopulation of ALDHhigh cells in human non-small cell lung cancer: A chance for targeting cancer stem cells?" which reported that a comparison between ALDH high cells and CD44 cells have been previously described with no significant correlation. This cross-sectional study analyzed the expression of ALDHhigh/low cells and the positivity for CD44 and epithelium cell adhesion molecule antigens in surgical lung cancer tissues. There was a highly positive correlation between the expressions of ALDHhigh and CD44 /EPCAM cells, with a Pearson’s correlation coefficient equal to 0.69, and Spearman’s correlation coefficient equal to 0.52. The average paired difference between the expression of ALDHhigh and CD44 /EPCAM cells was very close to 0, being 0.1%; there was no difference between these subpopulations in terms of means. The Oncotarget author’s study is the first attempt that identifies a high correlation between the ALDHhigh and the CD44 /EPCAM cells, thus suggesting the possibility to use this superficial marker for future target treatments against lung cancer stem cells. Dr. Beatrice Aramini from The University of Modena and Reggio Emilia said, "The cancer stem cell (CSC) model was proposed over 30 years ago [1] and is a very important field of study in cancer research." As a cancer stem cell marker in a panel of 11 non-small-cell lung cancer tumor samples, 45 NSCLC lines, and 7 small-cell lung cancer lines. In 2013 a panel of lung cancer cell lines from primary tumors and characterized a small subpopulation as strongly positive for CD44, with the main population being weakly positive or negative for CD44. The co-expression of CD90 further narrowed down the putative stem cell population. This showed the putative lung CSC phenotypes of CD166 /CD44 and CD166 /EPCAM with multipotent characteristics of stem cells in lung adenocarcinoma cells. Hence, a triple-positive marker, EPCAM /CD166 /CD44, has recently been described in the human non-small cell lung cancer cell line. Nevertheless, although ALDH is considered an intracellular enzyme and is the most used marker to identify CSCs in lung cancer, the scientific community has never correlated this intracellular marker with an epithelial marker, which may be very useful for targeting lung cancer stem cells. The Aramini Research Team concluded in their Oncotarget Research Paper, “even if we hypothesized that the percentage of CD44 /EPCAM in ALDHhigh cell population would be less than 50% in other patients, the similarity of an intracellular marker highlighting ALDHhigh cell population with a superficial marker CD44 /EPCAM is a very important concept in terms of target treatment. In summary, our research is an important starting point for further studies that are needed to better define the CD44 /EPCAM superficial marker highlighting lung cancer stem cells.” Full text - https://www.oncotarget.com/article/27568/text/

How are stem cells being used to treat cancer and develop future therapies? Hear from patients, physicians and researchers in this engaging panel. Moderated by Scott Lippman, MD, UC San Diego Sandra Dillon: Patient Perspective Tannishtha Reya, PhD, UC San Diego: Targeting stem cell signals in cancer progression and therapy resistance Robert A.J. Signer, PhD, UC San Diego: Stem cell regulation by the proteostasis network Karen Aboody, MD, City of Hope: Neural Stem Cell Targeted Anti-Cancer Therapies: From Bench to Bedside Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36361]

How are stem cells being used to treat cancer and develop future therapies? Hear from patients, physicians and researchers in this engaging panel. Moderated by Scott Lippman, MD, UC San Diego Sandra Dillon: Patient Perspective Tannishtha Reya, PhD, UC San Diego: Targeting stem cell signals in cancer progression and therapy resistance Robert A.J. Signer, PhD, UC San Diego: Stem cell regulation by the proteostasis network Karen Aboody, MD, City of Hope: Neural Stem Cell Targeted Anti-Cancer Therapies: From Bench to Bedside Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36361]

How are stem cells being used to treat cancer and develop future therapies? Hear from patients, physicians and researchers in this engaging panel. Moderated by Scott Lippman, MD, UC San Diego Sandra Dillon: Patient Perspective Tannishtha Reya, PhD, UC San Diego: Targeting stem cell signals in cancer progression and therapy resistance Robert A.J. Signer, PhD, UC San Diego: Stem cell regulation by the proteostasis network Karen Aboody, MD, City of Hope: Neural Stem Cell Targeted Anti-Cancer Therapies: From Bench to Bedside Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36361]

How are stem cells being used to treat cancer and develop future therapies? Hear from patients, physicians and researchers in this engaging panel. Moderated by Scott Lippman, MD, UC San Diego Sandra Dillon: Patient Perspective Tannishtha Reya, PhD, UC San Diego: Targeting stem cell signals in cancer progression and therapy resistance Robert A.J. Signer, PhD, UC San Diego: Stem cell regulation by the proteostasis network Karen Aboody, MD, City of Hope: Neural Stem Cell Targeted Anti-Cancer Therapies: From Bench to Bedside Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36361]

How are stem cells being used to treat cancer and develop future therapies? Hear from patients, physicians and researchers in this engaging panel. Moderated by Scott Lippman, MD, UC San Diego Sandra Dillon: Patient Perspective Tannishtha Reya, PhD, UC San Diego: Targeting stem cell signals in cancer progression and therapy resistance Robert A.J. Signer, PhD, UC San Diego: Stem cell regulation by the proteostasis network Karen Aboody, MD, City of Hope: Neural Stem Cell Targeted Anti-Cancer Therapies: From Bench to Bedside Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36361]

How are stem cells being used to treat cancer and develop future therapies? Hear from patients, physicians and researchers in this engaging panel. Moderated by Scott Lippman, MD, UC San Diego Sandra Dillon: Patient Perspective Tannishtha Reya, PhD, UC San Diego: Targeting stem cell signals in cancer progression and therapy resistance Robert A.J. Signer, PhD, UC San Diego: Stem cell regulation by the proteostasis network Karen Aboody, MD, City of Hope: Neural Stem Cell Targeted Anti-Cancer Therapies: From Bench to Bedside Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36361]

How are stem cells being used to treat cancer and develop future therapies? Hear from patients, physicians and researchers in this engaging panel. Moderated by Scott Lippman, MD, UC San Diego Sandra Dillon: Patient Perspective Tannishtha Reya, PhD, UC San Diego: Targeting stem cell signals in cancer progression and therapy resistance Robert A.J. Signer, PhD, UC San Diego: Stem cell regulation by the proteostasis network Karen Aboody, MD, City of Hope: Neural Stem Cell Targeted Anti-Cancer Therapies: From Bench to Bedside Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36361]

How are stem cells being used to treat cancer and develop future therapies? Hear from patients, physicians and researchers in this engaging panel. Moderated by Scott Lippman, MD, UC San Diego Sandra Dillon: Patient Perspective Tannishtha Reya, PhD, UC San Diego: Targeting stem cell signals in cancer progression and therapy resistance Robert A.J. Signer, PhD, UC San Diego: Stem cell regulation by the proteostasis network Karen Aboody, MD, City of Hope: Neural Stem Cell Targeted Anti-Cancer Therapies: From Bench to Bedside Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36361]

How are stem cells being used to treat cancer and develop future therapies? Hear from patients, physicians and researchers in this engaging panel. Moderated by Scott Lippman, MD, UC San Diego Sandra Dillon: Patient Perspective Tannishtha Reya, PhD, UC San Diego: Targeting stem cell signals in cancer progression and therapy resistance Robert A.J. Signer, PhD, UC San Diego: Stem cell regulation by the proteostasis network Karen Aboody, MD, City of Hope: Neural Stem Cell Targeted Anti-Cancer Therapies: From Bench to Bedside Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36361]

How are stem cells being used to treat cancer and develop future therapies? Hear from patients, physicians and researchers in this engaging panel. Moderated by Scott Lippman, MD, UC San Diego Sandra Dillon: Patient Perspective Tannishtha Reya, PhD, UC San Diego: Targeting stem cell signals in cancer progression and therapy resistance Robert A.J. Signer, PhD, UC San Diego: Stem cell regulation by the proteostasis network Karen Aboody, MD, City of Hope: Neural Stem Cell Targeted Anti-Cancer Therapies: From Bench to Bedside Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36361]

At 28, Sandra Dillon was diagnosed with myelofibrosis, a life-threatening blood disorder that can lead to acute leukemia. After participating in clinical trials and cutting edge treatments, Dillon has a deep appreciation for personalized medicine and genomics. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36357]

At 28, Sandra Dillon was diagnosed with myelofibrosis, a life-threatening blood disorder that can lead to acute leukemia. After participating in clinical trials and cutting edge treatments, Dillon has a deep appreciation for personalized medicine and genomics. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36357]

At 28, Sandra Dillon was diagnosed with myelofibrosis, a life-threatening blood disorder that can lead to acute leukemia. After participating in clinical trials and cutting edge treatments, Dillon has a deep appreciation for personalized medicine and genomics. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36357]

At 28, Sandra Dillon was diagnosed with myelofibrosis, a life-threatening blood disorder that can lead to acute leukemia. After participating in clinical trials and cutting edge treatments, Dillon has a deep appreciation for personalized medicine and genomics. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36357]

At 28, Sandra Dillon was diagnosed with myelofibrosis, a life-threatening blood disorder that can lead to acute leukemia. After participating in clinical trials and cutting edge treatments, Dillon has a deep appreciation for personalized medicine and genomics. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36357]

At 28, Sandra Dillon was diagnosed with myelofibrosis, a life-threatening blood disorder that can lead to acute leukemia. After participating in clinical trials and cutting edge treatments, Dillon has a deep appreciation for personalized medicine and genomics. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36357]

At 28, Sandra Dillon was diagnosed with myelofibrosis, a life-threatening blood disorder that can lead to acute leukemia. After participating in clinical trials and cutting edge treatments, Dillon has a deep appreciation for personalized medicine and genomics. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36357]

At 28, Sandra Dillon was diagnosed with myelofibrosis, a life-threatening blood disorder that can lead to acute leukemia. After participating in clinical trials and cutting edge treatments, Dillon has a deep appreciation for personalized medicine and genomics. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36357]

At 28, Sandra Dillon was diagnosed with myelofibrosis, a life-threatening blood disorder that can lead to acute leukemia. After participating in clinical trials and cutting edge treatments, Dillon has a deep appreciation for personalized medicine and genomics. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36357]

At 28, Sandra Dillon was diagnosed with myelofibrosis, a life-threatening blood disorder that can lead to acute leukemia. After participating in clinical trials and cutting edge treatments, Dillon has a deep appreciation for personalized medicine and genomics. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36357]

Thank you for joining us for our 2nd Cabral HouseCall of the weekend! I’m looking forward to sharing with you some of our community’s questions that have come in over the past few weeks… Let’s get started!    Susanne:Hi! The last year I have been getting tons of Cherry Angiomas appearing on my skin. I have no idea what the root cause might be. What makes them appear? What is the root cause? I am not pregnant or on birth control. If you had them, or they started appearing on your skin, Dr. Cabral, what would you do yourself to prevent getting more of them? Jennette: Hello, I finished the CBO protocol at the end of May but then I developed these small dry red patches under my eyes and on my right eye lid. I have been applying colloidal silver ointment which helps to clear it up but if I stop, it just comes back. it gets dry and flaky and someone was saying that it is eczema. I've never had this before and wondered what could be causing it? Valeria: Based off your podcasts on the emf vibrations impacting human vibration which can cause illness like cancer whats your take on fat loss ultrasonic devices? Tina: I am a personal trainer (who also thinks like a functional medicine practitioner!) and am working with a client who was recently diagnosed with sarcoidosis. Her health provider helped her link the root cause to exposure to bat or/and chicken manure. What are the essential next steps for this client? And if steroids are recommended, is this the best answer? Morgan: hi! what would you recommend for someone who has liver and colon cancer? Just wasn't sure which products to start with. thanks! Mishan: Hi Dr. Cabral! I'm so grateful to you for everything you do - you have changed my life for the best and I cannot thank you enough. My question is this - my aunt has rheumatoid arthritis and has been on steroids and biological meds for 30 years now. She does not want my help from IHP training, and instead she's considering stem cell treatment since she heard it "eliminates inflammation." I've understood that stem cells act more like anti-inflammatory substances in the body and do not address root causes. Can you speak about how stem cells work for RA - do they eliminate the root cause of the autoimmunity or are they still a bandaid approach? Thank you!! Kim: Hello Dr. Cabral, my name is Kim and I am 52 and have had Juvenile Type 1 Diabetes for 36 years. I have worn a insulin pump for the past 15 years. My last A1C was 6.1 and I fluctuates on my A1C between 5.7 to 6.3. I have been Keto for a year and half now and feel it has really helped with my blood sugars. I do IF daily for about 14-16 hours and eat 2 meals a day. I eat very clean with an occasional cheat meal or dessert for birthdays or holidays. I also belong to a gym and work out 3-4 days a week. My question is you don't recommend the keto diet and you encourage 3 meals a day and the first meal of the day being a smoothie. How does a diabetic adapt to that way of eating without needing added insulin? I keep my carbs below 50grams a day . I have food sensitivities to dairy and eggs and shell fish. I am also post menopausal and have digestive issues. I am not overweight I am 5'6 and weight 140 wear a size 6 in clothes. But I don't feel 100%. I wake up stiff and achy and actually dread going to bed because i do not sleep well and toss and turn all night do to aches and pains. Would love to hear you do an episode or 2 on Type 1 diabetes. Raj: Dear All,  I am keen undertaking the IHP training course offered by Dr Stephen Cabral and also would like to take the Big '5' Lab test. I love to workout and play football, go running, carry-out yoga and hit work outs regularly. I am from an Asian-Indian background, my father has Type 2 diabetes (is not too overweight but is heavy around the stomach) and mother is marginally obese but has never been diagnosed with anything. I would like to avoid this in the future. Before I go ahead, can you please tell me how I can prepare for tests and which tests I may need to improve my fitness and health. Although I am not a severe case but I do have mild symptoms of anxiety and depression (currently lowering medication off Sertraline). I have also taken live bacteria, to try and combat any bad bacteria. Diet has now changed to plain rice, carrot juice, loads of veg and salad and fish. However too much salad causes diarrhoea. I would really like to get better and help myself, so one day I can help others. I hope you can help me.   Thank you for tuning into this weekend’s Cabral HouseCalls and be sure to check back tomorrow for our Mindset & Motivation Monday show to get your week started off right! - - - Show Notes & Resources:  http://StephenCabral.com/1311 - - - Dr. Cabral's New Book, The Rain Barrel Effect https://amzn.to/2H0W7Ge - - - Join the Community & Get Your Questions Answered: http://CabralSupportGroup.com - - -   Dr. Cabral’s Most Popular Supplements: > “The Dr. Cabral Daily Protocol” (This is what Dr. Cabral does every day!) - - - > Dr. Cabral Detox  (The fastest way to get well, lose weight, and feel great!) - - - > Daily Nutritional Support Shake  (#1 “All-in-One recommendation in my practice) - - - > Daily Fruit & Vegetables Blend  (22 organic fruit & vegetables “greens powder”) - - - > CBD Oil  (Full-spectrum, 3rd part-tested & organically grown) - - - > Candida/Bacterial Overgrowth, Leaky Gut, Parasite & Speciality Supplement Packages - - - > See All Supplements: https://equilibriumnutrition.com/collections/supplements  - - -   Dr. Cabral’s Most Popular At-Home Lab Tests: > Hair Tissue Mineral Analysis (Test for mineral imbalances & heavy metal toxicity) - - - > Organic Acids Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Thyroid + Adrenal + Hormone Test  (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Adrenal + Hormone Test (Run your adrenal & hormone levels) - - - > Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Omega-3 Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - > Stool Test (Use this test to uncover any bacterial, h. Pylori, or parasite overgrowth) - - - > Genetic Test (Use the #1 lab test to unlocking your DNA and what it means in terms of wellness, weight loss & anti-aging) - - - > Dr. Cabral’s “Big 5” Lab Tests (This package includes the 5 labs Dr. Cabral recommends all people run in his private practice) - - - > View all Functional Medicine lab tests (View all Functional Medicine lab tests you can do right at home for you and your family)

In this episode, I discuss the role fasting can play on cancer, stem cells, and our immune system - some astounding results. Study: https://www.ncbi.nlm.nih.gov/pubmed/26094889 YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0

Dr. Michael F. Clarke is a professor at Stanford Medical School and Associate Director of the Institute for Stem Cell Biology and Regenerative Medicine. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. M.F. Clarke. Clinical and Therapeutic Implications of Cancer Stem Cells. N Engl J Med 2019;380:2237-2245.

In this week's episode Professor Paola Scaffidi from the Francis Crick Institute talks to us about how epigenetic factors influence cancer stem cells in cancer development, what cancer stem cells are, and what gets her up in the morning! Professor Scaffidi is an established Group Leader at the Francis Crick Institute since 2015. Her group use genome-wide mapping approaches and state-of-the-art cell biological methods in combination with advanced light microscopy techniques and in vivo approaches to characterise functionally important epigenetic traits of Cancer Stem Cells, with the ultimate goal of identifying novel therapeutic targets. For more information follow the link: https://www.crick.ac.uk/research/a-z-researchers/researchers-p-s/paola-scaffidi/

Paul Anderson, ND, shares insights from his 25-year career in treating complex diseases with natural remedies, with a focus on cancer. We discuss exciting new research about how natural therapies affect cancer development and progression and how the once chemo-and-radiation-centered field of oncology is embracing lower side effect therapies: keto, fasting and immune modulators. New Book: Outside the Box Cancer Therapies: https://amzn.to/2rC2PMe Connect with Dr. Paul: http://www.drabooks.com ----New Low-Carb eCourse------------ Raw Veggie Bread Creations: https://courses.highintensityhealth.com/p/raw-veggie-bread-creations-spring   ----Key Timestamps------------     03:24 Dr. Anderson’s travel health strategies. 05:03 Breast cancer recurrence dropped with fasting 05:21 The biochemistry changes after 3 to 4 months of intermittent fasting of 13 to 14 hours, even in non-cancer patients. 07:29 Intermittent fasting. 09:02 Hospitals are embracing intermittent fasting around chemo 11:15 People who respond best to natural treatment are those who tend to the basics and take care of their overall health. 13:42 Chemotherapy has evolved in the past 5 to 10 years to be more targeted. 15:08 Some targeted chemotherapies work well, others have deadly side effects or cancer coming back stronger. 16:10 The trophoblastic theory is the cancer stem cell theory. Once the main cancer tumor has been destroyed, the cancer stem cells step back and wait. 18:27 The more we quiet inflammation and regulate blood sugar, the less likely it is that cancer stem cells will activate. 19:19 Secondary prevention includes and goes beyond diet and lifestyle. Other issues must be addressed: immune issues, chronic infections in the lymphatic system, toxin burdens, and hormonal aberrations. 24:36 Aberrant thoughts affect the immune system. 28:03 Cancer stem cells stay with the blueprint and the rest are the soldier cancer cells that we see. The stem cells, are generally not affected by the treatment that destroys the soldiers. 29:53 Cancer stem cells have the ability to recruit and program normal cells. The harder we hit the cancer soldier stem cells with chemo radiation, the more the stem cells back away from the area and wait. 31:06 The strategy is to keep cancer stem cells happy and quiet. 33:44 A very low carb or keto diet was a common link in cancer patients that did the best with their therapies, longer remissions or no recurrence. 37:13 Research has found that integrative cancer therapies extended lifespan, compared to only standard therapy. 41:29 Work with at least two practitioners to get many options and varied care. 49:07 By the time we can see a cancer tumor with imaging, it has been growing slowly for 5 to 10 years or longer. 51:00 Prescreening tests are getting better. Next generation testing, which still has some gaps, looks for things like circulating cancer cells. 52:06 Some traditional testing of non-specific inflammatory markers show metabolic shifts to an inflammatory milieu or a milieu that shows Warburg Effect. 58:38 Thermography, when done correctly, can detect and track cancer. 01:03:28 Dr. Anderson tests all cancer survivors for chronic infection, including the family of HHV, mycoplasma, c pneumoniae and more. 01:05:21 People who eat mushrooms regularly have lower rates of certain cancers. Some cancers that do not respond to anything else, will respond to mushrooms. 01:10:45 High protein intake and low quality protein sources can bring you out of cancer fighting mode and out of ketosis. Poor quality protein, and food in general, can bring toxins into your body. 01:14:18 The ideal morning routine for preventing cancer starts with a quiet mind and centering. Exercise in the morning for the brain and body. Hydrate. 01:18:27 Dr. Anderson would choose curcumin as his desert island supplement. Curcumin levels out cytokines and triggering molecules. 01:22:33 Dr. Anderson’s elevator pitch: keep people from developing cancer to is to get them to do the things that bring their metabolism back to its intended balance.

08 April 2014: Listen as Dr. Anand Reddi, from the University of Colorado School of Medicine, Denver, discusses the correlation between microRNA-9 expression and the expansion of cancer stem cells in SCC metastasis.

Dr Keith Chan speaks with ecancertv at AACR 2016 about ongoing research to target cancer stem cells. Cancer stem cells are steadfastly resistant to traditional therapies, and can repopulate tumour cells in the same way as a healthy body heals a wound. This repopulation, Dr Chan reports, can come during the pauses between a patient's therapies, and is infact stimulated by the cell death caused by chemotherapy. Dr Chan discusses ways to target these stem cells during and before their pluripotent repopulation, and covers potential avenues for further research.

Dr Arafat speaks with ecancertv at ESMO 2016 about TRAIL, an apoptotic receptor - ligand pairing with modulated expression in cancer cells, which he believes could restore cell death to tumours. He considers delivery systems by which TRAIL might be introduced, and its synergistic potential with chemotherapy or radiotherapy.

Norris Cotton Cancer Center Grand Rounds - Diwakar R. Pattabiraman Ph.D. Senior Research Associate, Whitehead Institute for Biomedical Research

City of Hope researchers are working to uncover how cancer stem cells grow, and what can be done to stop them from multiplying. To figure that out, they study how certain proteins interact with a cell’s genetic material — and how that affects the complex processes that make cancer cells divide.Listen in as Leo David Wang, M.D., Ph.D. explains how our team at City of Hope, comprises stem cell biologists, cancer researchers and clinicians, nanotechnologists, bioinformaticians and graduate students all working toward a common goal: targeting cancer stem cells to suppress tumor formation and enhance patient survival.

Dr Cristina Maccalli (Italian Network for Biotherapy of Tumours, Siena, Italy) talks to ecancertv at the 1st Immunotherapy of Cancer Conference ( ITOC ) in Munich about immuno-biological properties of human cancer stem cells. Understanding these cells could lead to understanding chemotherapy resistance, and it appears that the cells have the potential to play an immunoregulatory role in T-cell response Cells with 'stem cell properties', denominated cancer stem cells (CSCs), have been recently isolated from a variety of human solid tumours. These cells have been considered as responsible of resistance to standard therapy such as chemotherapy and radiotherapy. Immunotherapy, due to its specificity and lack of toxicity can represent a promising approach to target cancer stem cells. Thus, it is relevant to assess whether CSCs isolated from solid tumours, can be exploited as source of antigens to elicit T cell-mediated immune responses and to design novel immunotherapeutic protocols for tumours. CSCs from glioblastoma multiforme (GBM) and colorectal cancer (CRC) have been isolated from tumour biopsies and have been biologically characterized. Moreover, a detailed immunological characterization of these CSCs has been performed leading to the identification of a low immunogenic profile with negative immunoregulatory properties. Dr Maccalli's team found that both CSCs and the differentiated counterpart of tumours (FBS tumour cells) expressed immune modulatory molecules, such as CTLA-4, PD- 1, PDL-1 and B7H3, with, in some cases, higher levels in CSCS vs. FBS tumour cells. Multiple mechanisms of immunoregulation that are exploited by CSCs to escape from T cell-mediated surveillance have been identified. These results may allow designing more effective immunotherapy protocols to target CSCs from GBM and/or CRC patients.

The cancer stem cell hypothesis implicates that tumor cell population is heterogeneous with relatively well-differentiated cells and poorly-differentiated cells. Only the small population of tumourigenic poorly-differentiated CSCs can escape the normal limits of self-renewal and has the ability to proliferate and maintain the malignant growth of the tumor. One characteristic of stem cell is that the ability to exclude DNA dyes, such as Hoechst 33342 via the over-expression of ATP-binding cassette transporters (ABC transporters) on the cell membrane. It makes the detecting of the stem cell possible. After the Hoechst 33342 staining, stem cells extrude this dye and show a typical profile of low fluorescence in Hoechst red versus Hoechst blue bivariate dot plots. These low Hoechst 33342 stained cells are named as side population (SP) cells. This characteristic has enabled purification and characterization of CSCs when carried out alone or in combination with stem cell surface markers. The CSC hypothesis could have a fundamental influence on cancer therapy. CSCs have shown significant substantial resistance to conventional chemotherapy in contrast to the differentiated cancer cells. It is essential to design a complete therapy strategy first to reduce or minimize proliferating cell mass and then to differentiate or eliminate CSCs, so that the relapses of metastatic cancers could be prevented. This work aimed at investigating if Hedgehog pathway inhibitor GDC-0449 is effective in the lung cancer cell lines HCC (adeno-carcinoma) and H1339 (small cell lung carcinoma) and also the cisplatin resistant lung cancer cells, and if possible effects of GDC-0449 are mediated via SPs. Furthermore, the effect of GDC-0449 on the calcium homeostasis was also investigated. GDC-0449 showed dose-dependent inhibitory effects on cell growth in both HCC and H1339 cells. The combination of GDC-0449 and cisplatin gave an additional inhibitory effect. GDC- 0449 could also inhibit the cell growth in cisplatin resistant HCC and H1339 cells. SP cells as cancer stem-cell-like cells could be found in HCC and H1339 cells. Only the SP cells showed the repopulation ability but not the non-SP cells. GDC-0449 could inhibit the SP cell fraction in both HCC and H1339 cells. So the inhibitory effect of GDC-0449 on cell growth may be mediated via SP. GDC-0449 affected the expression of the Hh pathway components in both HCC and H1339 cells. In HCC cells, GDC-0449 inhibited the activity of the Hh pathway and the down- regulation of Shh, Patched and Gli-1 could be shown. In H1339 cells, GDC-0449 could also inhibit the pathway activity and decrease the expression of Gli-1 in an autocrine pattern due to the over-expression of Shh. The inhibition of Hh pathway increased the expression of Bmi-1 to compensate the loss of Hh pathway function. The Hh pathway activity could be detected only in SP cells from HCC and H1339 cells. The application of GDC-0449 on HCC and H1339 naïve and cisplatin resistant cells increased [Ca2+]c by decreasing [Ca2+]ER. GDC-0449 induced Ca2+ release from ER into cytoplasm in HCC and H1339 naïve and cisplatin resistant cells. The Ca2+ overload could lead to apoptosis, which was related to the cell growth inhibitory effect of GDC-0449 in lung cancer cells. The expression of SERCA and IP3R was not detectably influenced by GDC-0449. The effect of GDC-0449 on lung cancer cell Ca2+ -regulating machinery was not via the alternation of the expression of ER Ca2+ regulating channels.

http://www.einstein.yu.edu - Paul Frenette, M.D., puts into perspective the promise and challenge of stem cell research as well as established and experimental stem cell treatments. Also meet three young researchers who work in Dr. Frenette’s lab: instructor Christoph Scheiermann, postdoc Sandra Pinho, and Mount Sinai School of Medicine M.D./Ph.D student Jalal Ahmed. Dr. Frenette is director of the Ruth A. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research at Albert Einstein College of Medicine of Yeshiva University. This edition of Einstein On, a research and medicine podcast, is hosted by Gordon Earle, associate dean for communications and public affairs.

Dr Max Wicha talks about the session he chaired at the AACR 2012 Annual Meeting on clinical implications of cancer stem cells and large number of trials underway examining these cells. He also highlights two examples; the effects of anti-angiogenic agents on cancer stem cells and role of HER 2 in driving cancer stem cells in human breast cancer.

The existence of cancer stem cells (CSCs) is receiving increasing interest particularly due to its potential ability to enter clinical routine. Rapid advances in the CSC field have provided evidence for the development of more reliable anticancer therapies in the future. CSCs typically only constitute a small fraction of the total tumor burden; however, they harbor self-renewal capacity and appear to be relatively resistant to conventional therapies. Recent therapeutic approaches aim to eliminate or differentiate CSCs or to disrupt the niches in which they reside. Better understanding of the biological characteristics of CSCs as well as improved preclinical and clinical trials targeting CSCs may revolutionize the treatment of many cancers. Copyright (c) 2012 S. Karger AG, Basel

In this month's Cell Podcast, we learn about the challenges of applying genetics to human mental health, with Trevor Robbins (0:00), a game of vesicular cat and mouse between bacterial lipids and the immune system, with Michael Brenner (10:48), and the shifting identities of stem-like cells in breast cancer, with Eric Lander (17:18).

Pier Giuseppe Pelicci, IEO, Milan, Milan - Italy speaks on "Cancer stem cells". This seminar has been recorded at University of Trieste by ICGEB Trieste

Giovanni Blandino, Translational Oncogenomic Unit, Regina Elena Cancer Institute, Rome, ITALY speaks on "Exploring tumor chemoresistance: miRNAs and cancer stem cells". This seminar has been recorded by ICGEB Trieste

Thu, 20 Jan 2011 12:00:00 +0100 https://edoc.ub.uni-muenchen.de/12644/ https://edoc.ub.uni-muenchen.de/12644/1/Damianoff_Karin.pdf Damianoff, Karin ddc:610, ddc:600, Medizinische

Learn about an X chromosome variant that protects against the progression of AIDS (start 0:50), hear about a microRNA that is decreased in both normal and cancer stem cells (start 8:08), and learn about migrating cells in the worm embryo (start 17:08).