Podcasts about Leukemia

In this week's episode, we'll learn about rapid, high-sensitivity diagnostic assays for TTP, or thrombotic thrombocytopenic purpura, that can reduce unnecessary treatments. After that: enhancing PD-1 blockade in relapsed/refractory extranodal NK/T-cell lymphoma. In a single-arm, phase 2 study, combined CD38 and PD-1 inhibition demonstrated durable responses and manageable safety. Finally, a lymphoma horror story with a happy ending. CREBBP mutations create a zombie enzyme that competes with its wild-type counterparts. By enforcing CD40 signaling, a bispecific antibody overcomes this effect and induces lymphoma cell death.Featured Articles:Rapid ADAMTS13 activity assays for thrombotic thrombocytopenic purpura: a systematic review and meta-analysisEfficacy of combined CD38 and PD-1 inhibition with isatuximab and cemiplimab for relapsed/refractory NK/T-cell lymphomaBlunted CD40-responsive enhancer activation in CREBBP-mutant lymphomas can be restored by enforced CD4 T-cell engagement

ICYMI, this hot take episode originally aired in April of this year. One of America's most notorious TV moms sat down with me and gave me a great interview. Barbara Bregoli, the mother of Danielle Bregoli, famously known as Bhad Bhabie or the "Cash Me Outside" girl. Barbara shared her life story, from her Brooklyn upbringing and career in finance to the challenges of being a single mother. She opened up about the infamous Dr. Phil appearance, clarifying misconceptions and discussing Bhad Bhabie's evolution into a rapper. Barbara also revealed her personal battles with breast cancer and the impact on her family, as well as the recent news of Dani's leukemia diagnosis. Through it all, Barbara's resilience and unwavering support for her daughter shone brightly, offering a deeply personal and inspiring narrativeTimestamps:00:00:00 - Introduction and Guest Welcome00:00:20 - Barbara Bregoli's Background and Dr. Phil Appearance00:00:50 - The Origin of "Catch Me Outside" Phrase00:28:03 - Bhad Bhabie's Leukemia Diagnosis00:30:36 - Alabama Barker Feud, Bhad Bhabie's OF earnings and more00:35:17 - The Kardashian's, Bhad Bhabie's future goals and moreMY Go Big Podcasting Courses Are Here! Purchase Go Big Podcasting and learn to start, monetize, and grow your own podcast. Use code DAD15 for 15% OFF until 6/30/2025**SHOP my Amazon Marketplace - especially if you're looking to get geared-up to start your own Podcast!!!**https://www.amazon.com/shop/thesarahfrasershowShow is sponsored by:ASPCA Pet Insurance to explore coverage, visit A-S-P-C-A pet insurance dot com slash TSFS.Horizonfibroids.com get rid of those nasty fibroidsNutrafol.com use code TSFS for FREE shipping and $10 off your subscriptionQuince.com/tsfs for FREE shipping on your order and 365 day returnsRula.com/tsfs to get started today. That's R-U-L-A dot com slash tsfs for convenient therapy that's covered by insurance.Thrivecosmetics.com/tsfs Brighten a mom's day—especially if you're that mom. Go to thrivecausemetics.com/TSFS for 20% OFF your orderFollow me on Instagram/Tiktok: @thesarahfrasershow ***Visit our Sub-Reddit: reddit.com/r/thesarahfrasershow for ALL things The Sarah Fraser Show!!!***Advertise on The Sarah Fraser Show: thesarahfrasershow@gmail.comGot a juicy gossip TIP from your favorite TLC or Bravo show? Email: thesarahfrasershow@gmail.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Do we have another comet visiting from outside the solar system? What is Oumuamua? Is the Ring of Fire amping up in activity? Is leukaemia genetic? Does exposure to certain chemicals increase your risk of cancer? Why are early health screenings so important? How do you measure the risk of certain health treatments? Dr Chris Smith and Clarence Ford have all the answers... Like this podcast? Please help us by supporting the Naked Scientists

Do we have another comet visiting from outside the solar system? What is Oumuamua? Is the Ring of Fire amping up in activity? Is leukaemia genetic? Does exposure to certain chemicals increase your risk of cancer? Why are early health screenings so important? How do you measure the risk of certain health treatments? Dr Chris Smith and Clarence Ford have all the answers... Like this podcast? Please help us by supporting the Naked Scientists

Patty Furco's then 4 year old daughter Abby was diagnosed with Pre B Cell Acute Lymphoblastic Leukemia in 2011, a diagnosis which was changed 2 weeks later to Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia. This diagnosis reduced Abby's chances of survival to 20 percent. Patty will talk about the 10 years that Abby was able to somehow survive this very difficult form of Leukemia, which included her doctors saying that she had 48 hours to live in May of 2016. Patty and her husband very sadly began to make funeral arrangements and as Abby's time was supposedly nearing its end, somehow she recovered and was able to live another 5 years until her passing in October of 2021. 

In this week's episode we'll learn more about a novel mouse model that recapitulates many of the properties of human sickle cell SC disease; results from the induction phase of the risk-adapted MIDAS trial of isatuximab, carfilzomib, lenalidomide, and dexamethasone in newly diagnosed, transplant-eligible multiple myeloma; and a link between splicing factor mutations and competitive fitness in myelodysplastic syndrome stem cells.Featured articles:A novel mouse model of hemoglobin SC disease reveals mechanisms underlying beneficial effects of hydroxyureaIsatuximab, carfilzomib, lenalidomide, and dexamethasone induction in newly diagnosed myeloma: analysis of the MIDAS trialCell-autonomous dysregulation of interferon signaling drives clonal expansion of SRSF2-mutant MDS stem/progenitor cells

In this episode of the Braun Performance & Rehab Podcast, Dan is joined by Alexa Degan to discuss her recovery from 2 ACL injuries. Alexa Degan is a resilient and driven ice hockey player currently competing at the collegiate level for Long Island University. A 2023 graduate of Morristown-Beard School, Alexa played four standout seasons of varsity hockey, helping her team secure three state championships and one co-championship. Over her freshman and sophomore seasons, she tallied seven goals and 25 assists, earning first-team all-state honors before overcoming the challenge of two ACL injuries that sidelined her.In addition to hockey, Alexa competed in two varsity lacrosse seasons and demonstrated strong leadership off the field as well. She co-captained a fundraising campaign that raised an impressive $122,000 for the Leukemia & Lymphoma Society, showcasing her commitment to making a broader impact.Alexa is the daughter of Christa and Sean Degan and has two brothers, Justin and Ayden. Her story is one of perseverance, leadership, and dedication—both on and off the ice.For more on Alexa, be sure to follow @torn2triumphant*SEASON 6 of the Braun Performance & Rehab Podcast is brought to you by Isophit. For more on Isophit, please check out isophit.com and @isophit -BE SURE to use coupon code BraunPR25% to save 25% on your Isophit order!**Season 6 of the Braun Performance & Rehab Podcast is also brought to you by Firefly Recovery, the official recovery provider for Braun Performance & Rehab. For more on Firefly, please check out https://www.recoveryfirefly.com/ or email jake@recoveryfirefly.com***This episode is also powered by Dr. Ray Gorman, founder of Engage Movement. Learn how to boost your income without relying on sessions. Get a free training on the blended practice model by following @raygormandpt on Instagram. DM my name “Dan” to @raygormandpt on Instagram and receive your free breakdown on the model.Episode Affiliates:MoboBoard: BRAWNBODY10 saves 10% at checkout!AliRx: DBraunRx = 20% off at checkout! https://alirx.health/MedBridge: https://www.medbridgeeducation.com/brawn-body-training or Coupon Code "BRAWN" for 40% off your annual subscription!CTM Band: https://ctm.band/collections/ctm-band coupon code "BRAWN10" = 10% off!Ice shaker affiliate link: https://www.iceshaker.com?sca_ref=1520881.zOJLysQzKeMake sure you SHARE this episode with a friend who could benefit from the information we shared!Check out everything Dan is up to by clicking here: https://linktr.ee/braun_prLiked this episode? Leave a 5-star review on your favorite podcast platform

In this powerful episode of the Medical Sales U Podcast, I sit down with Nick Rich—cancer survivor, AYA advocate, and now a Senior Oncology Account Specialist at Pfizer. Nick opens up about his deeply personal journey from battling cancer to building a career in oncology sales, where he now helps bring life-saving treatments to patients fighting the very diseases he once faced.We discuss how his diagnosis shaped his purpose, the pivotal moments that led him into medical sales, and how his fundraising team helped raise over $50,000 for the Leukemia and Lymphoma Society. You'll hear the grit behind his transition from patient to professional, and how he channels his pain into purpose every day on the job.Whether you're in sales, healthcare, or simply looking for inspiration, this conversation will move you. Nick's story is a testament to resilience, faith, and the impact of using your story to serve others.

Will Yank is a 2020 graduate from Wabash College who is also a member of Phi Gamma Delta Fraternity. At 21 years old, he was diagnosed with leukemia and septic shock, and now he speaks on reclaiming hope, something that is a very important lesson for us all to consider when life throws us a curveball and we start to feel pain, failure, or regret. Today we're going to hope for something. In episode 581 of the Fraternity Foodie Podcast, we find out why Will decided on Wabash College, what made him want to join Phi Gamma Delta Fraternity, what it was like to be diagnosed with leukemia and septic shock at 21 years old, why hope is more than just a “feel-good” emotion, why having a future vision so important for college students today, what we can do for students who feel like they have no one to lean on, how students can turn past pain, failure, or regret into a teacher instead of a burden, how to support members going through difficult mental health or life challenges, what is one action students can take right now to reclaim a sense of hope, and what his legacy will be for this generation of college students. Enjoy!

In this week's episode, we'll learn about using AI to assess transplant risk in myelofibrosis. In a step toward personalized medicine, researchers report on a machine learning model that identifies 25% of patients with poor outcomes. After that: preventing priapism in men with sickle cell anemia. A recent phase 2 feasibility study shows high rates of recruitment, retention, and adherence to oral therapies, coupled with a significant reduction in the risk of this difficult complication. Finally, new research indicates that hallmarks of terminal T-cell exhaustion are absent in multiple myeloma, from diagnosis through maintenance therapy. We explore these provocative and counterintuitive findings arising from profiling of blood and marrow samples.Featured Articles:Use of machine learning techniques to predict poor survival after hematopoietic cell transplantation for myelofibrosisA controlled trial for preventing priapism in sickle cell anemia: hydroxyurea plus placebo vs hydroxyurea plus tadalafilHallmarks of T-cell exhaustion and antigen experience are absent in multiple myeloma from diagnosis to maintenance therapy

When Laura's daughter was diagnosed with leukemia, her world stopped. What followed was a powerful journey through fear, resilience, and fierce advocacy. In this episode, Laura DeKraker Lang-Ree—a lifelong educator and now author of The Cancer Parent's Handbook—opens up about the most terrifying day of her life, how she transformed pain into purpose, and why parent-to-parent support is critical in the childhood cancer community. Her reflections are raw, heartfelt, and offer wisdom for every parent facing a medical diagnosis with their child. 

Cedar Connell was 15 years old when he found himself on his way to Lurie Children's Hospital in Chicago to begin his treatment for B Cell Acute Lymphoblastic Leukemia in 2022. Cedar and his mom Kiki will talk about the difficult treatment that he went through, including his move from Chicago to the Dana Farber Cancer Institute in Boston in 2023. Cedar is now getting ready to do his part for the Leukemia and Lymphoma Society as TEAM CONNELLSLLS will be getting ready for a 31 day challenge beginning on July 1st and ending on August 1st to exercise 3 miles each day for that time period, in the hope that they raise 35,000.

Omg Bravo Bosses! I interviewed Jared Lipscomb from The Valley and so we are skipping our typical reality roundup up today in favor of this interview which was chock FULL OF TEA! You can watch this episode on YouTube! If you don't know Jared, you're about to. Jared started off as the makeup artist for the Vandercrew and became a stable fixture in the lives of the cast members as they progressed to The Valley. Since Jared has been around for many years, he knows the truth about our favorite Bravo stars that we love to hate and he's ready to TELL ALL! We talked about Zach's demonic words that couldn't be said on tv, why he is furious at some cast members for being in the comments, what Dark Side Danny REALLY looks like as well as where the fans have it wrong about Janet. We also get into Jared's fascinating backstory in drag and in makeup, we talk about his cancer journey and lastly, Jared tells the story of how he was integrally involved in Britney Spears' conservatorship battle! Follow Jared on IG @jaredlips and Listen to This Side of the Hill wherever you get your podcasts! For more information on participation in and donations for Leukemia and Lymphoma follow: @llsusa and @nmdp_org Thank you to our SPONSORS! ⁠⁠⁠Petscosset ⁠⁠⁠- Use code: GS15 for 15% off any product! Doodle - Doodle is a user-friendly scheduling platform that helps individuals and teams easily find meeting times, book appointments, and organize events. For a limited time, get 20% off here with CODE: AFFILIATE-20. Rubbish Home - Rubbish makes garbage bags that make trash less day less painful and more enjoyable.We've made your garbage bag dreams come true with our 13-gallon trash bags. Each box includes a fun saying and a reminder when you're low on garbage bags. Our compostable, non-toxic, and PFAS-free trash bags break down quickly and 10% of our garbage bags go to charity. Rubbish does everything your current garbage bags don't! You can purchase my new RE-BRANDED The Bravo Investigator Merch ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠!  Subscribe to Hurrdat Entertainment's ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠YouTube Channel⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for full length video episodes!  Follow me on Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@thebravoinvestigator⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  Follow me on Tik Tok: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@thebravoinvestigator⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  Email me your questions or suggestions: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Brunchandbravo@gmail.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  This is another Hurrdat Media Production. Hurrdat Media is a podcast network and digital media production company based in Omaha, NE. Find more podcasts on the Hurrdat Media Network by going to HurrdatMedia.com or the Hurrdat Media YouTube channel!  Learn more about your ad choices. Visit megaphone.fm/adchoices

In this week's episode, we'll learn more about social determinants of health that impact access to allogeneic hematopoietic cell transplantation in patients with acute myeloid leukemia, or AML; use of megakaryocyte growth factor receptor-based stem cell depletion as part of pretransplant conditioning in ex vivo autologous gene therapy; and identification of an eight-protein risk signature as well as a novel single protein biomarker, soluble oncostatin M receptor, for risk stratification in AML.Featured Articles:Social Determinants of Health and Access to Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid LeukemiacMPL-Based Purification and Depletion of Human Hematopoietic Stem Cells: Implications for Pretransplant ConditioningBlood-Based Proteomic Profiling Identifies OSMR as a Novel Biomarker of AML Outcomes

In today's episode, we had the pleasure of speaking with Alexey Danilov, MD, PhD, about current challenges and emerging treatment approaches for the management of leukemia and lymphoma that were published in a manuscript based on proceedings from the inaugural Bridging the Gaps in Leukemia, Lymphoma, and Multiple Myeloma Conference. Dr Danilov is the Marianne and Gerhard Pinkus Professor of Early Clinical Therapeutics, medical director of the Early Phase Therapeutics Program for the Systems Clinical Trials Office, co-director of the Toni Stephenson Lymphoma Center, and a professor in the Division of Lymphoma in the Department of Hematology & Hematopoietic Cell Transplantation at City of Hope in Duarte, California. In our exclusive interview, Dr Danilov highlighted recent advances and controversies in the treatment of select patients with hematologic malignancies. He noted chemotherapy-free regimens that are shifting treatment paradigms in mantle cell lymphoma, preferred and emerging BTK inhibitors for the management of chronic lymphocytic leukemia, and the evolution of CD19-directed CAR T-cell therapies for diffuse large B-cell lymphoma. Dr Danilov concluded by taking a forward glance at future developments like BTK degraders and novel CAR T-cell therapy targets.

Blood editor Dr. Laurie Sehn discusses the topic of "Aggressive non-Hodgkin lymphoma: defining and managing high-risk subsets" featuring Drs. Mark Roschewski, Grzegorz Nowakowski, and Neha Mehta-Shah, who each contributed to the articles featured in the review series on high-risk aggressive lymphoma.See the full review series on high risk lymphoma in volume 144, issue 25 of Blood.

This episode of Marrow Masters brings us an incredible conversation with Kitrena Young, a two-time cancer survivor whose story spans decades and highlights the unique challenges faced by adolescents and young adults (AYAs). We begin by learning about Kitrena's initial diagnosis of B-cell ALL with a Philadelphia chromosome at the age of eight, followed by a shocking relapse 23 years later. Her candor about how she recognized the early signs the second time around—bruising and fatigue—underscores the importance of self-awareness and advocacy.We discuss how navigating the adult healthcare system differed drastically from her pediatric experience. Kitrena takes us through her rapid efforts to get an urgent appointment and the emotional toll of being thrust back into the cancer world. With support from her brother and eventually finding care at the Memorial Sloan Kettering Cancer Center (MSKCC)  through a compassionate voice on the phone, she exemplifies what it means to be proactive in your care journey.Fertility preservation is another focal point. Kitrena recounts her decision to freeze 15 eggs before starting treatment and how her perspective on parenthood has evolved. She walks us through the emotional and physical realities of exploring surrogacy and genetic testing post-transplant—particularly the complex issue of donor DNA requiring a skin biopsy for viable results.Kitrena doesn't shy away from discussing post-treatment life: weight gain linked to early menopause, a challenging international trip filled with setbacks and triumphs, and the frustrations of altered tastes and capabilities. Despite it all, she maintains a remarkable sense of humor and determination to continue traveling and living fully.Family and caregiver dynamics are woven throughout her story. She speaks lovingly about her partner's unwavering support and the strength of her younger brother, who stepped up when needed most. Her message to caregivers includes practical advice—especially around vigilance with medical billing, noting errors she encountered from appointments she never attended.Finally, Kitrena emphasizes the growing importance of therapy for both patients and caregivers. She encourages the AYA community to use available resources to work through trauma, grief, and uncertainty—pointing to virtual options that didn't exist in her earlier experience.Kitrena's journey is one of persistence, clarity, and empowerment. She brings vital, firsthand wisdom to the AYA cancer space, reminding us that while every survivor's path is different, no one should walk it alone.Thanks to our Season 17 Sponsors:Leukemia and Lymphoma Society (LLS): https://lls.org/and Incyte: https://incyte.com/FInancial Resource from the LINK: https://www.nbmtlink.org/financebookresources/ National Bone Marrow Transplant Link - (800) LINK-BMT, or (800) 546-5268.nbmtLINK Website: https://www.nbmtlink.org/nbmtLINK Facebook Page: https://www.facebook.com/nbmtLINKFollow the nbmtLINK on Instagram! https://www.instagram.com/nbmtlink/The nbmtLINK YouTube Page can be found by clicking here.To participate in the GVHD Mosaic, click here: https://amp.livemosaics.com/gvhd

In this incredible episode of Marrow Masters, we sit down with Kayla West, a stem cell donor from Texas, and Miriam Bauer, the mother of a young leukemia survivor Miley, from Oklahoma. This story is a deeply emotional journey of hope, resilience, and a connection that transcends bloodlines. Kayla and Miriam take us through the entire transplant process from both perspectives: the donor stepping up during a pandemic, and the caregiver navigating a life-threatening diagnosis in a child.We begin with Kayla's decision to join the donor registry after a chance encounter with DKMS at a Goo Goo Dolls concert. She didn't expect to be called to donate, but when she was, during COVID lockdown, she jumped at the chance to help someone—anyone—in need. That “anyone” turned out to be Miley, an eleven-year-old girl who had been diagnosed with acute myeloid leukemia (AML) and urgently needed a transplant after two brutal rounds of chemotherapy.Miriam recounts those terrifying early days at St. Jude, from the moment of diagnosis through the chaos of the early pandemic lockdowns. She was Miley's only caregiver during a 248-day hospital stay. Her story is filled with moments of heartbreak and triumph, from failed chemo rounds to the joy of reaching remission and finding a viable donor in Kayla. We learn how transplant coordination works, how donor cells were frozen and shipped during COVID, and how little details—like celebrating donor day or choosing a transplant date that coincides with family birthdays—brought joy in dark times.Post-transplant, Miley's life has been a mix of recovery and lingering health effects, but she's thriving. Miriam emphasizes advocacy, honesty, and self-care for caregivers. Kayla, for her part, reflects on the overwhelming emotion of learning she was a match, undergoing all the testing during COVID, and then finally meeting the recipient of her cells in an unforgettable reunion in New York. The two families, now bonded for life, meet regularly and have built a deep friendship.  Next up: A trip for Kayla's family to Oklahoma to experience a powwow with Miriam, Miley, and their family!The videos below will have you reaching for the tissues and hopefully inspire many to get swabbed.Kayla also shares her decision to launch a nonprofit, SETX Leukemia Organization, focused on educating communities and recruiting new donors. Her goal is to prevent other families from facing what Miriam's did—wondering if there will be a match in time. Kayla's drive, born from her experience, continues to ripple outwards as she recruits more potential donors at local events with DKMS support.This episode isn't just about survival—it's about connection, purpose, and what can happen when strangers become family through an act of extraordinary generosity.SETX Leukemia Organization (Kayla's nonprofit): https://setxleukemia.org/DKMS (Be The Match partner organization): https://www.dkms.orgDKMS Video about Kayla, Miley, and Miriam: https://www.youtube.com/watch?v=sNhwRxXMbw8Thanks to our Season 17 Sponsors:Leukemia and Lymphoma Society (LLS): https://lls.org/and Incyte: https://incyte.com/ National Bone Marrow Transplant Link - (800) LINK-BMT, or (800) 546-5268.nbmtLINK Website: https://www.nbmtlink.org/nbmtLINK Facebook Page: https://www.facebook.com/nbmtLINKFollow the nbmtLINK on Instagram! https://www.instagram.com/nbmtlink/The nbmtLINK YouTube Page can be found by clicking here.To participate in the GVHD Mosaic, click here: https://amp.livemosaics.com/gvhd

In today's episode, supported by Shorla Oncology, we had the pleasure of speaking with Kate Gasparini, PharmD, BCOP, BCPPS, about the use of the oral formulation of imatinib (Imkeldi) for pediatric and adult patients with select leukemias and other malignancies. Gasparini is a pediatric oncology clinical pharmacy specialist at Memorial Sloan Kettering Cancer Center in New York, New York. In our exclusive interview, Gasparini discussed her role as a clinical pharmacy specialist in pediatric oncology, emphasizing her work in patient care, medication reviews, and supportive care. She also noted challenges in administering treatments to patients with dysphagia and emphasized the need for liquid formulations of common therapies. She explained the significance of the availability of the liquid formulation of imatinib, sharing its benefits for patients who struggle with swallowing. Gasparini also addressed potential barriers to accessing this medication, such as insurance coverage limitations, as well as the importance of considering the volume and palatability of liquid formulations to avoid adverse effects and ensure treatment adherence.

Celebrating Fathers and the Impact of FatherhoodIn this special Father's Day episode of the Truman Charities podcast, host Jamie Truman celebrates fathers, particularly her husband Jerry Truman, co-founder of Truman Charities. Jamie outlines how Truman Charities started with Jerry's initiative to raise funds for Leukemia research and has since grown, raising over $2 million. She discusses the significant impact fathers have within the family unit and the alarming statistics on youths without fathers. Jamie shares insights from her book 'Vanishing Fathers: The Ripple Effect on Tomorrow's Generation,' which explores the societal consequences of fatherlessness. Proceeds from the book support at-risk youth charities. The episode features discussions with notable individuals impacted by fatherlessness,00:00 Introduction and Father's Day Wishes00:26 The Origin of Truman Charities01:23 The Importance of Fathers04:10 Vanishing Fathers: The Book04:28 Notable Interviews and Stories06:34 Supporting At-Risk Youths06:54 Final Thoughts and Upcoming EventsConnect with Jamie at Truman Charities:FacebookInstagramLinkedInWebsiteYouTubeEmail: info@trumancharities.comThis episode was post produced by Podcast Boutique https://podcastboutique.com/

In today's episode, we spoke with Naval Daver, MD, about the evolving role of menin inhibition in acute myeloid leukemia (AML) and emerging data with revumenib (Revuforj) presented across ongoing clinical trials. Dr Daver is a professor in the Department of Leukemia and director of the Leukemia Research Alliance Program at The University of Texas MD Anderson Cancer Center in Houston, Texas.

In this week's episode, we' ll learn about how TET3 has a key role in GVHD. In mice, a deficiency of Tet3 in donor T cells inhibited pathogenic immunoglobulin class switching and suppressed lung fibrosis. Accordingly, TET3 may be a new therapeutic target in chronic GVHD. After that: rilzabrutinib, a BTK inhibitor for ITP. In a randomized, placebo-controlled trial, treatment produced rapid and durable platelet responses, with acceptable safety, in adults with immune thrombocytopenia who had failed multiple previous therapies. Finally: exploring pre-TCR surface expression patterns in T-cell ALL. Co-inhibition of the interleukin-7 receptor and pre-T cell receptor pathways may play a therapeutic role for a subset of T-lymphoblastic leukemias.Featured Articles: Deficiency of T follicular helper cell Tet3 DNA demethylation inhibits pathogenic IgG2c class switching and chronic GVHDSafety and efficacy of rilzabrutinib vs placebo in adults with immune thrombocytopenia: the phase 3 LUNA3 studySurface pTα expression predicts LCK activation and preclinical synergy of LCK and JAK coinhibition in adult T-ALL

Valerie David, also known as The Pink Hulk, is a three-time cancer survivor (non-Hodgkin's lymphoma, stage 2 breast cancer, and stage 4 metastatic breast cancer) who turned her journey of resilience into an award-winning one-woman show. Through humor, raw honesty, and advocacy, she inspires audiences worldwide—proving that even cancer won't stop her from taking center stage.Check out Valerie's show, The Pink Hulk here: https://pinkhulkplay.comKey Highlights:- Valerie trusted her inner voice when symptoms appeared, even when doctors initially dismissed them. If you are able to get second opinions, advocate for yourself, and listen to your gut, you'll find this to be useful in other parts of your own life.- Balancing intuition with fear over symptoms can be tricky, but Valerie advises: don't panic over nothing, don't choose to live in fear. Instead, stay proactive by communicating with your care team about any arising symptoms.About our guest:Valerie David is an actor, playwright, writer and editor. Her greatest accomplishment in life is being a three-time cancer survivor. She was diagnosed and treated for Stage III Non-Hodgkin's Lymphoma in 1999, Stage II Breast Cancer in 2014 and 2015, and Stage IV Breast Cancer in 2018. As of April 2019, she has beaten cancer again! Valerie reactivated her superhero within, and exactly 5 months after receiving hormone treatment only in pill form–no surgery, no radiation, no chemotherapy, Valerie no longer has active disease. She has since kept up a full schedule of performances–nothing has stopped her. Valerie's inspirational solo show, The Pink Hulk, has been accepted into almost 50 different play festivals worldwide since its 2016 debut, won multiple awards and has been touring since its very first performance, impacting audiences with the show's universal message of hope and empowerment. She has performed in over 25 different cities and globally, including in England, Sweden, Iceland, and Finland. A graduate of the American Academy of Dramatic Arts, her credits include the Off-Broadway production of A Stoop on Orchard Street, Cookie in Rumors and Claudia Shear's Blown Sideways Through Life. Films: How I Became that Jewish Guy, which premiered at a November 2015 NYC Film Festival, and Bridges and Tunnels. Valerie volunteers as a motivational speaker at the Leukemia & Lymphoma Society's Team in Training events and Make-A-Wish Foundation. As a marathon cyclist, she co-founded Cycle of Hope, which raises money for national and international cancer organizations through bike marathons. Her most recent biking event raised almost $5,000 for the American Cancer Society and the Leukemia & Lymphoma Society.Key Moments:At 7 minutes 28 seconds “What is my choice? Is my choice going to live in fear every single day? Is it going to be well, we'll deal with it when it happens. So I think what I've learned from cancer is don't worry until there's something to worry about.”Disclaimer: All content and information provided in connection with Manta Cares is solely intended for informational and educational purposes only. This content and information is not intended to be a substitute for medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.

In this special episode, Dr. Shaji Kumar from the Mayo Clinic speaks with Blood editor Dr. Laurie Sehn on a paper recently published in Blood, "Eliminating the Need for Sequential Confirmation of Response in Multiple Myeloma". The findings demonstrate eliminating the need for sequential confirmation of response in multiple myeloma. The study, involving 583 episodes of progression, found that simultaneous confirmation of disease progression using two different markers (e.g., serum protein electrophoresis and serum free light chain assay) was 98% accurate, compared to 82% for sequential confirmation. This suggests that simultaneous confirmation could improve clinical trial accuracy and reduce false censoring. The International Myeloma Working Group is set to revise its response criteria to incorporate these findings, potentially simplifying disease assessment and reducing the need for multiple blood draws.

Iron County plan to take Beaver County water stirs controversy -- Chad Saunders on Leukemia & Lymphoma Society fundraising challenge

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In this How I Treat Series episode Dr. Thomas Ortel leads a discussion with author Dr. Patrick Foy on his paper “How I diagnose and treat thrombocytopenia in geriatric patients”. See the full How I Treat series on geriatric hematology in volume 143 issue 3 of Blood Journal.

In this week's episode, we'll learn more about the identification and characterization of stem cell-like leukemia blasts using single cell multi-omics, cyclophosphamide as a treatment for non-immune effector cell-associated neurotoxicity in patients treated with B-cell maturation antigen, or BCMA, targeted CAR T-cell therapies, and how differences in glycosylation affect the clearance of human plasma-derived and recombinant von Willebrand factor concentrates.Featured Articles:Single-cell panleukemia signatures of HSPC-like blasts predict drug response and clinical outcomeCyclophosphamide mitigates non-ICANS neurotoxicities following ciltacabtagene autoleucel treatmentEnhanced α2-3–linked sialylation determines the extended half-life of CHO-rVWF

In this week's episode, we'll hear about new insights into PU.1-mutated agammaglobulinemia. Researchers show that haploinsufficiency of the master transcriptional regulator PU.1 causes agammaglobulinemia and dendritic cell deficiencies. These patients experience an array of infectious and non-infectious complications, but not leukemia. After that: venetoclax-based induction therapy in younger patients with AML. Venetoclax plus decitabine was associated with superior safety and non-inferior response rates compared to intensive chemotherapy. Is it time to consider lower-intensity therapy beyond older and unfit patients? Finally, a focus on venous thromboembolism. Researchers link BGAT, an enzyme pivotal to determining blood type, to risk of future VTE. They say high plasma levels of BGAT contribute to risk above and beyond what can be explained by von Willebrand factor and Factor VIII.Featured Articles:One hundred thirty-four germ line PU.1 variants and the agammaglobulinemic patients carrying themVenetoclax and decitabine vs intensive chemotherapy as induction for young patients with newly diagnosed AMLHisto–blood group ABO system transferase plasma levels and risk of future venous thromboembolism: the HUNT study

Livvy Bedard and Caeleigh Brown met while on the Swimming Team in Middle School. Caeleigh was diagnosed with Leukemia while a member of this team in January of 2017, shortly after setting her personal best during a swimming meet. Caleigh is now a Nursing Student at James Madison University. Livvy is working with the Leukemia and Lymphoma Society as she attempts to become a Visionary of the Year by raising money in honor of Caeleigh and what she went through. Livvy began this quest on March 27th and has an upcoming fundraising deadline of June 5th. 

In this conversation, Jeff interviews MK Holmes, the campaign development manager for the Light the Night campaign with the Leukemia & Lymphoma Society (LLS). They discuss MK's background, her journey to LLS, and the impactful work the organization does in the community, particularly through events like Light the Night and the Pickleball for a Purpose tournament. MK shares insights into LLS's mission to cure blood cancers, the support they provide to patients, and how the community can get involved through fundraising and volunteering.Leukemia and Lymphoma SocietyCLICK HERE to donate to Jamie's Light the Night FundraiserCLICK HERE to register for Charlotte Light The Night 2025Special thanks to:The Carolina Factory & The Vannelle Family---------------------------------------------------------------------------------------The Best of LKNhttps://thebestoflkn.com/Hosted by:Jeff HammReal Estate BrokerCharlotte & Lake Norman (NC)https://lknreal.com/Support the show

In this episode of the Epigenetics Podcast, we talked with Ani Deshpande from Sanford Burnham Prebys about his work on epigenetic regulation and developing small molecules through high throughput screens for AML. Throughout our discussion, we delve into Dr. Despande's journey into the field of biology and science, tracing his evolution from a literature enthusiast in Mumbai to a dedicated cancer researcher. He reflects on his formative experiences during his PhD at Ludwig Maximilian University in Munich, where she developed murine models for refractory acute myeloid leukemia (AML). We examine these models' contributions to therapeutic discovery and understanding the intricate mechanisms underscoring AML's complexities. Transitioning to his postdoctoral work at Scott Armstrong's lab in Boston, Dr. Despande shares his insights on the importance of epigenetic regulators, such as DOT1L, in leukemias, and how they can serve as strategic therapeutic targets. His ambitious pursuit of translational research is further highlighted through his efforts in developing a conditional knockout mouse model and his collaborative work utilizing CRISPR technology to refine our understanding of epigenetic regulation in cancer pathogenesis. Moreover, we engage in a conversation about the challenges and opportunities that arise when establishing his lab at Sanford Burnham Prebys. Dr. Despande candidly discusses the delicate balance between pursuing topics of genuine interest versus adhering to grant fundability, underlining the tension researchers face in the current scientific landscape. His emphasis on the critical need for innovation within lab settings serves as a motivational call for emerging scientists to venture beyond the established templates that often inhibit groundbreaking discoveries. We conclude our dialogue with an exploration of his recent projects, which involve targeting specific epigenetic modifiers and how his lab's findings can contribute to greater understanding and potential treatments for not only AML but also other pediatric cancers driven by gene fusions. Dr. Despande's insights into the integration of modern technologies, such as CRISPR libraries, exemplify his commitment to pushing the boundaries of cancer research. In addition to discussing his scientific contributions, we touch upon Dr. Despande's foray into podcasting (The Discovery Dialogues), shedding light on his motivation to bridge the communication gap between scientists and the broader public. He articulates his desire to demystify scientific discoveries and promote awareness about the intricate journey of research that lays the groundwork for medical advancements. This multidimensional discussion not only highlights his scientific achievements but also emphasizes the importance of effective science communication in fostering public understanding and appreciation of research.   References Deshpande AJ, Cusan M, Rawat VP, Reuter H, Krause A, Pott C, Quintanilla-Martinez L, Kakadia P, Kuchenbauer F, Ahmed F, Delabesse E, Hahn M, Lichter P, Kneba M, Hiddemann W, Macintyre E, Mecucci C, Ludwig WD, Humphries RK, Bohlander SK, Feuring-Buske M, Buske C. Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia. Cancer Cell. 2006 Nov;10(5):363-74. doi: 10.1016/j.ccr.2006.08.023. PMID: 17097559. Deshpande AJ, Deshpande A, Sinha AU, Chen L, Chang J, Cihan A, Fazio M, Chen CW, Zhu N, Koche R, Dzhekieva L, Ibáñez G, Dias S, Banka D, Krivtsov A, Luo M, Roeder RG, Bradner JE, Bernt KM, Armstrong SA. AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes. Cancer Cell. 2014 Dec 8;26(6):896-908. doi: 10.1016/j.ccell.2014.10.009. Epub 2014 Nov 20. PMID: 25464900; PMCID: PMC4291116. Sinha S, Barbosa K, Cheng K, Leiserson MDM, Jain P, Deshpande A, Wilson DM 3rd, Ryan BM, Luo J, Ronai ZA, Lee JS, Deshpande AJ, Ruppin E. A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing. Nat Commun. 2021 Nov 11;12(1):6512. doi: 10.1038/s41467-021-26788-6. Erratum in: Nat Commun. 2022 May 16;13(1):2828. doi: 10.1038/s41467-022-30475-5. PMID: 34764240; PMCID: PMC8586238.   Related Episodes Targeting COMPASS to Cure Childhood Leukemia (Ali Shilatifard) The Menin-MLL Complex and Small Molecule Inhibitors (Yadira Soto-Feliciano) MLL Proteins in Mixed-Lineage Leukemia (Yali Dou)   Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com

In this week's episode we'll learn about how frequent blood donation affects clonal hematopoiesis in older, male blood donors; the effect of immune microenvironment on response to bispecific antibodies in diffuse large B-cell lymphoma; and the feasibility of adding blinatumomab to early consolidation therapy in CD19-positive Ph-negative B-cell acute lymphoblastic lymphoma.Featured ArticlesClonal Hematopoiesis Landscape in Frequent Blood DonorsIntegrative genomic analysis of DLBCL identifies immune environments associated with bispecific antibody responseUpfront Blinatumomab Improves MRD Clearance and Outcome in Adult Ph-negative B-lineage ALL: The GIMEMA LAL2317 Phase 2 Study

In part two of the How I Treat Series on Transfusion Medicine Dr. Erica Wood interviews the "How I Manage Major Hemorrhage" author group: Drs. Jeannie Callium, Keyvan Karkouti, and Ron George.Find the full published review series in Volume 145 Issue 20 of Blood Journal.

A funeral homily for Mr. Peter Rebello at the church of St. Clement in Toronto on May 20, 2025. Peter died from Leukemia on May 13, the feast of our Lady of Fatima. He was 77.Music: Be not afraid by Bob Dufford with choir.org

- Understanding Precision Medicine: Overview & Value of Precision Medicine - How Precision Medicine is Different from Targeted Treatments? - Precision Medicine's Role in Informing Treatment Decisions: Predicting Response to Treatment - The Role of Precision Medicine in Deciding the Treatment for Lung Cancer, Leukemia & Colon Cancer - Talking with Your Health Care Team About Precision Medicine & its Benefits - The Role of the Pathologist - OpenNotes – Asking Your Health Care Team & Pathologist to Help You Understand OpenNotes - How Precision Medicine Contributes to Treatment Options & Quality of Life - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology & Prepared List of Questions - Questions for Our Panel of Experts

- Understanding Precision Medicine: Overview & Value of Precision Medicine - How Precision Medicine is Different from Targeted Treatments? - Precision Medicine's Role in Informing Treatment Decisions: Predicting Response to Treatment - The Role of Precision Medicine in Deciding the Treatment for Lung Cancer, Leukemia & Colon Cancer - Talking with Your Health Care Team About Precision Medicine & its Benefits - The Role of the Pathologist - OpenNotes – Asking Your Health Care Team & Pathologist to Help You Understand OpenNotes - How Precision Medicine Contributes to Treatment Options & Quality of Life - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology & Prepared List of Questions - Questions for Our Panel of Experts

- Understanding Precision Medicine: Overview & Value of Precision Medicine - How Precision Medicine is Different from Targeted Treatments? - Precision Medicine's Role in Informing Treatment Decisions: Predicting Response to Treatment - The Role of Precision Medicine in Deciding the Treatment for Lung Cancer, Leukemia & Colon Cancer - Talking with Your Health Care Team About Precision Medicine & its Benefits - The Role of the Pathologist - OpenNotes – Asking Your Health Care Team & Pathologist to Help You Understand OpenNotes - How Precision Medicine Contributes to Treatment Options & Quality of Life - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology & Prepared List of Questions - Questions for Our Panel of Experts

Angela started her career as a critical care nurse in 2014. She received her first MSN in 2017 with an emphasis in public health. In 2022, she received her 2nd MSN in Adult/Gerontology Acute Care Nurse Practitioner. She and her husband have been practicing the Keto Diet since 2019 (which was right before COVID and one of their children being diagnosed with Leukemia); with all the stressors that they faced, the Keto Diet kept them healthy and happy through the worst. Disenchanted by modern medicine after learning about the keto diet and reluctant to make the transition as an NP, Angela found her way into Home Health as a Telehealth Primary and Palliative Care NP. Timestamps: 00:00 Trailer 01:25 Introduction 03:15 Nurse practitioner's independence benefits 09:14 ICU nutrition oversights during Covid 11:58 Keto diet and health struggles 14:19 Diet scams vs. genuine support 19:10 Orthopedic surgeon embraces metabolic health 22:33 Low carb lifestyle and nutrition 27:41 Rapid monitoring of hypertension patients 29:42 Revero's unique healthcare model 32:28 Balancing work and family time 34:58 Nutrition and nursing home residents 38:48 Improving elder care nutrition 42:18 Patients' surprising knowledge on keto/carnivore 45:10 Patient struggles in gaining weight 51:13 Creating a positive impact for patients 52:05 Where to find Skye Join Revero now to regain your health: https://revero.com/YT Revero.com is an online medical clinic for treating chronic diseases with this root-cause approach of nutrition therapy. You can get access to medical providers, personalized nutrition therapy, biomarker tracking, lab testing, ongoing clinical care, and daily coaching. You will also learn everything you need with educational videos, hundreds of recipes, and articles to make this easy for you. Join the Revero team (medical providers, etc): https://revero.com/jobs ‪#Revero #ReveroHealth #shawnbaker  #Carnivorediet #MeatHeals #AnimalBased #ZeroCarb #DietCoach  #FatAdapted #Carnivore #sugarfree Disclaimer: The content on this channel is not medical advice. Please consult your healthcare provider.

Joao wants to know what happens when stem cells of our own, which have been cultivated outside the body, are reintroduced to the bloodstream. This got James Tytko thinking about autologous stem cell transplants, used as a treatment for some forms of blood cancer. He asked Tania Dexter, haematology registrar, and senior medical officer at the Anthony Nolan Institute, to help explain... Like this podcast? Please help us by supporting the Naked Scientists

In this week's episode, we'll learn about stopping myeloma maintenance therapy in the modern era. New research suggests that many patients in remission can discontinue lenalidomide, remaining treatment-free, without jeopardizing disease response. After that: a novel congenital neutropenia syndrome. Mutations in the COPZ1 gene impact myeloid differentiation and development of neutropenia. Researchers describe the mechanisms and propose a treatment strategy for restoring granulopoiesis. Finally, ruxolitinib maintenance therapy after allogeneic transplant. In a phase 2 study, this treatment strategy was associated with low rates of chronic graft-versus-host disease. Investigators say the use of JAK inhibitors in this context warrants further study.Featured Articles: Sustained bone marrow and imaging MRD negativity for 3 years drives discontinuation of maintenance post-ASCT in myelomaA new severe congenital neutropenia syndrome associated with autosomal recessive COPZ1 mutationsLow rates of chronic graft-versus-host disease with ruxolitinib maintenance following allogeneic HCT

In this two-part series, Dr. Erica Wood talks with Drs. Masja de Haas, Helen Savoia, and Stella Chou about their articles in the How I Treat Series on Transfusion Medicine. Topics include noninvasive prenatal testing for red blood cell and platelet antigens, transfusion cases in sickle cell disease, and pregnant patients who are alloimmunized to RBC antigens. Find the full published review series in Volume 145 Issue 20 of Blood Journal.

In this heartfelt episode of the Surviving Siblings Podcast, host Maya Roffler welcomes Cryssy, a bereaved sibling who lost her younger sister, Danielle, to acute myeloid leukemia in 2012. As the oldest sibling, Cryssy took on the role of protector, caregiver, and advocate—navigating the heartbreak of watching her sister battle a devastating illness. Cryssy shares her deeply personal journey of anticipatory grief, the pain of losing Danielle at just 21 years old, and the complex emotions of grieving while trying to stay strong for her family. She opens up about the regret of not getting to say goodbye the way she wanted, the physical toll grief took on her body, and the creative, meaningful ways she keeps Danielle's memory alive every day. This episode is a powerful conversation about sibling loss, anticipatory grief, and finding purpose after tragedy. Cryssy also shares how honoring her sister through traditions, a beloved stuffed animal, and small daily acts has helped her heal—and how grief can manifest physically in ways we might never expect. If you've ever felt the weight of grieving a sibling while being the “strong one” for others, Cryssy's story will remind you that love endures, even through the pain. In This Episode: (00:01:00) – Danielle: A Birthday Gift Sister Cryssy shares how Danielle was born just two days before her own birthday, how they celebrated together, and how their sibling bond was filled with love, chaos, and laughter. (00:04:00) – Big Sister, Protector, Mama Bear Growing up as the oldest, Cryssy stepped into a protective role, helping raise Danielle and their brother, shielding them, and taking on family responsibilities from a young age. (00:05:00) – The Call That Changed Everything Cryssy recounts the moment she learned Danielle was being rushed to the hospital after a bloody nose turned into a leukemia diagnosis—and how she instantly began grieving. (00:08:00) – Facing Acute Myeloid Leukemia Cryssy explains Danielle's diagnosis, the aggressive treatment process, and how she tried to stay hopeful on the outside while preparing herself internally for the worst. (00:11:00) – Holidays in the Hospital Danielle asked Cryssy to decorate her hospital room for Halloween and Christmas—keeping their family traditions alive despite spending their favorite holidays in a hospital room. (00:14:00) – The Final Christmas Together Cryssy reflects on their last Christmas, staying up all night talking, exchanging meaningful gifts, and creating treasured memories in what would be Danielle's final holiday. (00:19:00) – Saying Goodbye Without Words Cryssy shares the experience of Danielle's “surge” before passing, the bittersweet final days, and the deep regret of not being able to say goodbye the way she had hoped. (00:24:00) – Preparing Danielle's Goodbye Honoring her sister's love of style, Cryssy lovingly prepared Danielle for her viewing—painting her nails, doing her hair, dressing her in jewelry, and ensuring she looked radiant. (00:31:00) – A Dream Visit From Danielle Months after Danielle's passing, Cryssy had a vivid dream of Danielle smiling and telling her, “It's okay to be okay”—a powerful, healing moment that brought her comfort. (00:37:00) – Grief's Physical Impact Cryssy opens up about how her grief manifested in physical illness, leading to hospitalization, sepsis, and a near-death experience that she believes Danielle helped her survive. (00:48:00) – Finding Purpose in Grief Cryssy reflects on how grief has shaped her purpose, giving her strength to help others and reminding her that grief is love in a different form. This episode is sponsored by The Surviving Siblings  Connect with Cryssy:  Tik Tok: https://www.tiktok.com/@cryssycryssycryssy Email: Crystalmperry@yahoo.com Instagram: https://www.instagram.com/Nimbeedonut Facebook: https://www.facebook.com/CryssyPerry/ Connect with Maya: Podcast Instagram: https://www.instagram.com/survivingsiblingspodcast/ Maya's Instagram: https://www.instagram.com/mayaroffler/ TikTok: https://www.tiktok.com/@survivingsiblingspodcast Twitter: https://x.com/survivingsibpod Website: thesurvivingsiblings.com Facebook Group: The Surviving Siblings Podcast YouTube: The Surviving Siblings Podcast Patreon: https://www.patreon.com/TheSurvivingSiblingsPodcast  

Imagine the shock and horror of having a child be diagnosed with Acute Myeloid Leukemia, going through treatment for that for 8 months,, relapsing 2 months later, and then being told that the first diagnosis was wrong, and that the child actually had  Ewings Sarcoma. That is what happened to then 2 1/2 year old Connor Mocey who is now 5 years old and doing as well as possible while dealing with this difficult Bone Cancer. 

In this week's episode, we'll learn more about how measurable residual disease might help guide decisions about post-transplant gilteritinib maintenance in FLT3-ITD acute myeloid leukemia, or AML; how stemness contributes to chemotherapy resistance in AML; and effects of babesiosis on red blood cells from individuals with sickle cell disease, sickle cell trait, and wild-type hemoglobin. Featured Articles:Measurable residual disease and post-transplantation gilteritinib maintenance for patients with FLT3-ITD-mutated AML GATA2 links stemness to chemotherapy resistance in acute myeloid leukemia Babesiosis and Sickle Red Blood Cells: Loss of Deformability, Heightened Osmotic fragility and Hyper-vesiculation 

Enjoy a replay of Monday night's Patriots post-draft party co-hosted by Andrew and the Boston Herald's Doug Kyed. Together, they interview ESPN's Mina Kimes, Jason McCourty, Danny Kelly, Danny Heifetz, Phil Perry, Mike Giardi, Taylor Kyles, Michael Hurley, Sam Monson and Steve Palazzolo all about the Patriots draft and potential for next season. Donate at https://princesshallieforever.com — all proceeds go to Doug Kyed's Leukemia and Lymphoma fundraiser in honor of his daughter, Hallie. Pats Interference is presented by: Gametime! Take the guesswork out of buying NFL tickets with Gametime. Download the Gametime app, create an account, and use code CLNS for $20 off your first purchase. Download Gametime today. What time is it? Gametime! Terms apply. Go to ⁠⁠https://gametime.co⁠⁠ ! Learn more about your ad choices. Visit megaphone.fm/adchoices

After a short introduction, we replay what Andrew and several media members — Doug Kyed, Mike Giardi, Jeff Howe, Mark Daniels and Michael Hurley — said what the Patriots will and should do with the No. 4 overall pick during last week's live Patriots Draught Party at Vitamin Sea Brewing. Later, the guys offer their favorite mid-round prospects for the Patriots and answer audience questions. Support Doug and the Kyed Family! Donate Here to Help Raise Money for the The Leukemia & Lymphoma Society: https://pages.lls.org/voy/ma/ma25/dougkyed 0:00 Introduction 3:00 Who Should Patriots Take at 4? 6:00 Howe: It Will Be Will Campbell 10:45 Draft Crushes 18:03 Fan Questions 18:05 Will Patriots trade in draft? 19:44 Savage Sports asks question: Campbell or Membou? 27:19 Will Campbell or Mason Graham? 29:30 Fan defends Will Campbell 33:41 Patriots #4 Pick Predictiona Learn more about your ad choices. Visit megaphone.fm/adchoices

Special Patreon Re-Release: Love and Loss with James Jetton   James 1:2-4 (NIV) "Consider it pure joy, my brothers and sisters, whenever you face trials of many kinds, because you know that the testing of your faith produces perseverance. Let perseverance finish its work so that you may be mature and complete, not lacking anything."   **Transcription Below**   James Jetton's Bio: My name is James Jetton. I have and still do live a crazy beautiful, challenging, and blessed life. I am blessed to get to raise 4 beautiful children, and I have spent time getting to serve a fantastic community as a Recreation Minister, where I got to combine my love of Jesus, sports, and people. I served in this role for 13 years before my bride Kaetlin was diagnosed with Leukemia in 2020. Unfortunately, after an awe-inspiring journey with cancer, Kaetlin went to meet her Savior in January of 2022.   Clearly, this changed so much of my life trajectory. Currently, I'm working towards obtaining a Masters in Social Work to take the pain and experiences I have had to help others through their pain. Kaet and I were married in 2009 and built a beautiful life; we taught each other so much. So, I deeply desire to take everything we learned together and the lessons the Lord has taught me to help others.   I mentioned earlier that I have 4 exceptional children, Laken, 9, Isla Kaet, 7, Hattie, 6, and Ryder, 4. Laken is my go-getter; she is fearless, strong, and tough. Sweet Isla Kaet is a quiet thinker and planner and is often referred to as little Kaet. She cares deeply and is always looking for ways where she can help and take care of her family. Hattie is our child with special needs and has been diagnosed with GNB-1 Syndrome (a rare genetic disorder). Hattie will light up any room she is in; it's incredible that a child who only has a few words, uses a wheelchair, and is “limited” by our world's standards, can bring joy to people in a way that I never knew was possible. Ryder the caboose is a maniac, and his sisters affectionately call him “Wreck it Ryder” he has no fear and is a super extrovert; he keeps us all on our toes. He is what some would say, “all boy.”   This is a brief bio of me and our circus; through everything, we have found joy in all circumstances. Although there are exceptionally hard days as we have endured much grief, God has always provided, and I am thankful for the life God has given us.   Questions we discuss: Life took an unexpected twist in 2016. Will you catch us up on your discoveries that year? While many of us were in the midst of changing schedules and suddenly homeschooling children in May of 2020, your family was receiving even more news. Will you share that with us now? What is life like for your family these days, as grief likely comes at unexpected times?   Thank You to Our Sponsors: Chick-fil-A East Peoria and The Savvy Sauce Charities (and donate online here)   Connect with The Savvy Sauce on Facebook or Instagram or Our Website   Please help us out by sharing this episode with a friend, leaving a 5-star rating and review, and subscribing to this podcast!   Other Episodes from The Savvy Sauce of God's Faithfulness: 17 Being on Both Sides of Forgiveness with Adelle Dickie 18 Clinging to Jesus as I lived Through My Worst Nightmare with Angela Braker 19 Grief and Triumph and God's Pursuit Though it All with Julie Locke Moore 20 Joy in the Lord Even Through Tremendous Loss…Twice with Rachel Faulkner Brown 62 Unexpected Grief and What Helped Me Through It Can Help You Too with Singer and Blogger, Brittany Price Brooker 78 Parenting the Prodigal Child And God's Desire For Redemption With Mother-Daughter Duo, Claire Stanfill and Tindell Baldwin 79 Radical Business and Radical Parenting with Gary & Marla Ringger, Founders of Lifesong for Orphans 83 Miracles of God with Founder of Midwest Food Bank, David Kieser 120 Our Story for His Glory with Mercedes Cotchery 134 Fashion Meets Faith with Shari Braendel 141 Rescued from Poverty with Norah Birungi 143 Prodigal Story: Sexuality, Drugs, and Scripture with Dr. Christopher Yuan 160 Unleash This Generation with the Power of the Gospel with Greg Stier 161 God Redeems with Hettie Brittz 162 Healing from Spouse's Sexual Addiction with Jennifer Roush 174 Stories of God's Upside Down Economy with Kristen Welch 208 Tremendous Testimony and Adding Spark into Your Marriage with David & Teri Sumlin 223 Journey and Learnings as Former Second Lady of the United States with Karen Pence 229 Escape from Modern Day Sex Slavery with Rachel Timothy Special Patreon 28 Re-Release: What to Do When You Don't Like Your Story with Sharon Jaynes 231 Stories Series: Faith Building Miracles with Dave Pridemore 232 Stories Series: Testify to Glorify with Richard Gamble 233 Stories Series: Surprises from God with Tiffany Noel Special Patreon Re-Release: Patreon 30 Story of Perseverance with Jenny Boyett 234 Stories Series: Redemption From Sexual Sin in Marriage with Garrett and Brenna Naufel 235 Stories Series: Ever-Present Help in Trouble with Kent Heimer 236 Stories Series: God's Power and Light with Jaime Farrell 237 Stories Series: Prodigal and Redemption with Renee Endress Special Patreon Re-Release: Patreon 31 Unexpected Story of Trauma, Anxiety, Adoption, and Hope with Bettina Stevens 238 Stories Series: God Delights in His Children with Brad Habegger 239 Stories Series: Experiencing the Supernatural with Jackie Coleman 240 Stories Series: God's Rescue and Covering in Parenting with Brenda Dugger 241 Stories Series: From the Mission Field, Experiencing God in the Little and the Big with Patty Sommer 242 Stories Series: He Gives and Takes Away with Joyce Hodel 243 Stories Series: Angel Encounter and Hearing from God with Mary Beth Zimmerman 244 Stories Series: Medical Marvels with Carolyn Henricks 245 Stories Series: Miracles Big and Small with Dr. Rob Rienow 246 Stories Series: Experiencing God's Tangible Love with Jen Moore 247 Stories Series: Exciting Adventures Follow Radical Obedience with Susan Zobrist 248 Stories Series: Discipline of Celebration in the Midst of Unexpected Loss and Grief with Jonathan Pitts Special Patreon Re-Release: Patreon 49: Story of Healing from Sexual Betrayal in Marriage: An Interview with Bonny Burns 249 Stories Series Conclusion: Now What? Living as Global Christians with Todd Ahrend of The Traveling Team   Gospel Scripture: (all NIV)   Romans 3:23 “for all have sinned and fall short of the glory of God,”   Romans 3:24 “and are justified freely by his grace through the redemption that came by Christ Jesus.”   Romans 3:25 (a) “God presented him as a sacrifice of atonement, through faith in his blood.”    Hebrews 9:22 (b) “without the shedding of blood there is no forgiveness.”    Romans 5:8 “But God demonstrates his own love for us in this: While we were still sinners, Christ died for us.”    Romans 5:11 “Not only is this so, but we also rejoice in God through our Lord Jesus Christ, through whom we have now received reconciliation.”    John 3:16 “For God so loved the world that he gave his one and only Son, that whoever believes in him shall not perish but have eternal life.”   Romans 10:9 “That if you confess with your mouth, “Jesus is Lord,” and believe in your heart that God raised him from the dead, you will be saved.”    Luke 15:10 says “In the same way, I tell you, there is rejoicing in the presence of the angels of God over one sinner who repents.”   Romans 8:1 “Therefore, there is now no condemnation for those who are in Christ Jesus”   Ephesians 1:13–14 “And you also were included in Christ when you heard the word of truth, the gospel of your salvation. Having believed, you were marked in him with a seal, the promised Holy Spirit, who is a deposit guaranteeing our inheritance until the redemption of those who are God's possession- to the praise of his glory.”   Ephesians 1:15–23 “For this reason, ever since I heard about your faith in the Lord Jesus and your love for all the saints, I have not stopped giving thanks for you, remembering you in my prayers. I keep asking that the God of our Lord Jesus Christ, the glorious Father, may give you the spirit of wisdom and revelation, so that you may know him better. I pray also that the eyes of your heart may be enlightened in order that you may know the hope to which he has called you, the riches of his glorious inheritance in the saints, and his incomparably great power for us who believe. That power is like the working of his mighty strength, which he exerted in Christ when he raised him from the dead and seated him at his right hand in the heavenly realms, far above all rule and authority, power and dominion, and every title that can be given, not only in the present age but also in the one to come. And God placed all things under his feet and appointed him to be head over everything for the church, which is his body, the fullness of him who fills everything in every way.”   Ephesians 2:8–10 “For it is by grace you have been saved, through faith – and this not from yourselves, it is the gift of God – not by works, so that no one can boast. For we are God‘s workmanship, created in Christ Jesus to do good works, which God prepared in advance for us to do.“   Ephesians 2:13 “But now in Christ Jesus you who once were far away have been brought near through the blood of Christ.“   Philippians 1:6 “being confident of this, that he who began a good work in you will carry it on to completion until the day of Christ Jesus.”   **Transcription**   Music: (0:00 – 0:09)   Laura Dugger: (0:09 - 2:07) Welcome to The Savvy Sauce, where we have practical chats for intentional living. I'm your host, Laura Dugger, and I'm so glad you're here. I'm grateful for today's sponsor, Chick-fil-A East Peoria.   Check them out online to place your order for dining or catering, or to fill out an application to join their friendly team. Visit cfaeastpeoria.com. If you've been with us long, you know this podcast is only one piece of our nonprofit, which is The Savvy Sauce Charities.   Don't miss out on our other resources. We have questions and content to inspire you to have your own practical chats for intentional living. And I also hope you don't miss out on the opportunity to financially support us through your tax-deductible donations.   All this information can be found on our recently updated website, thesavvysauce.com. And now, I'm pleased to share this episode with you that used to only be available to paying patrons.    My guest for today is James Jetton.   Mark and I attended the same family camp as James in 2022. I observed a father who was very devoted to his children, and one of his precious daughters was in a wheelchair, which was always by his side. He was so tender with his children, and I just assumed his wife was resting while he was attending to the family.   I did not learn of his full story until after camp, and it was through a mutual friend, April Siervo. But then, after she shared a bit more of their story, I immediately reached out to James to request that he share his faith and testimony with us today. Here's our chat.   Welcome to The Savvy Sauce, James.   James Jetton: (2:07 - 2:15) I'm happy to be here. I'm looking forward to talking to you and just kind of sharing how God has moved in our lives the past few years.   Laura Dugger: (2:15 - 2:24) You have already lived through so much, but let's just start here. When did Jesus initially draw you to himself?   James Jetton: (2:26 - 3:25) Yeah, I think that's like, you know, it's a big question, right? But also, it shouldn't be. I think the first time I really just kind of came to know the Lord, I was in the eighth grade.   I had a retreat, and in that moment, for me, it was a situation of— it wasn't necessarily for me, but also just trying to do the right thing. I grew up in Birmingham, Alabama, so I was in the Bible Belt. I was like, this is what we're supposed to do.   We're supposed to give our lives to Jesus. But I would say probably going into my senior year of high school, I had some moments just kind of alone at a beach, actually. I was like, what am I doing with my life?   And I believe that that was kind of the first one real moment in my life where I decided, I think I'm going to actually follow the Lord now and not just do this, just to say I'm doing it. And so that was really the first time I really felt the Lord draw me to him. And then, of course, as time goes on, there's all these other little moments throughout where he's continually staying close and bringing me back to him when I feel like I'm drifting away and that sort of thing.   Laura Dugger: (3:27 - 3:39) Thank you for sharing that. And you've written before on your blog that, I'll quote, one of the best decisions I have ever made was when I persuaded Kaetlin to marry me, end quote.   James Jetton: (3:39 - 3:40) Yeah.   Laura Dugger: (3:40 - 3:43) James, how did the two of you meet and fall in love?   James Jetton: (3:44 - 5:30) Yeah, so we went to college together. We went to Troy University. I vividly remember a time where she was getting out of her car, and she didn't know me at this time.   But I remember seeing her. I think I met her maybe once or twice through some mutual friends. I remember seeing her get out of the car and literally, I'll never forget this moment.   I was like, man, if I could just have a girl like that. And it stuck with me. And I think the first time we met, I think I made some comments that she wasn't happy about, about some fraternity guys that were in a different fraternity than me that I didn't think too highly of.   But I didn't realize in that moment that she was actually the sweetheart of that fraternity. And so, we kind of got off to a little bad step there. But I remember she broke up with another boyfriend.   That was part of the reason I saw her. And I was like, I could never have a girl like that. All the girls like that are taken.   And so, she broke up with her boyfriend. I remember her best friend called me and was like, “Hey, can I bring her over to y'all's house? Because she just needs to laugh”.   I was like, “Well, we can do that. We can make sure she laughs”. And so, I think from there, we just kind of, I don't know, just we continued to talk.   And for some reason, she liked me a little bit and I liked her a whole lot. And we dated for about three years in college. And when we got out of college, we got married in May of 2009.   And so that was kind of where life began to speed up a lot at that point. But that was the first time I'll never forget those moments. And then there's other things throughout.   But I remember seeing her in the parking lot like that girl.   Laura Dugger: (5:31 - 5:43) So, I love that. And OK, so married in 2009 and then children came a little while later. So how many children did you add to your family?   James Jetton: (5:44 - 6:28) Yeah, we have four kids. Our first child was born in 2013. So, after we got married, we lived back here in Niceville for a little bit but then ended up moving.   She wanted to go to PA school, and I was working a job I didn't care too much for. So, I was like, how quickly can we go to school? And so, we moved to West Tennessee where she went to PA school.   And I ended up going to school there, too, because she studied all the time, and I was bored. And I was like, I guess I should do something productive as well. So that was 2009 and we had a lot of fun.   We love to travel, did a lot of fun things. And then in 2013, we had our first child, Laken.   Laura Dugger: (6:28 - 6:39) And then if you fast forward, life took an unexpected twist in 2016. So, will you catch us up on your discoveries that year?   James Jetton: (6:40 - 13:07) Yeah. So, we, you know, so we had Laken in 2013. Then, we had another part of our - we did have a miscarriage between Laken and Isla who was born in 2015. But then we had Hattie who was born in 2016.   And Hattie's our child with special needs. And she was born in - all of our pregnancies where we used to joke with people that could have babies and just bounce right back and have these beautiful, wonderful pregnancies. And they loved it.   That was not us. Every single one of our pregnancies brought some challenge within it. And so with Hattie, my wife started swelling a lot and kind of found out she had some clotting in her legs.   And so, we ended up having to induce labor for her with that happening. And, you know, when she my wife was also a PA in the ER. So, she understood medical things way better than I did.   I was kind of oblivious to a lot of things. So, she would probably say it was a little bit more scary than I realized it was when she was giving birth. But when Hattie came, like in some accounts, it just kind of seemed normal.   But she was having some trouble breathing. And so, she was in our hospital. In order to go to the NICU, you have to kind of get transferred out to a smaller hospital.   And so, they were keeping her under observation that night. And her breathing wasn't really getting a whole lot better. And they did x-rays and stuff like that, but couldn't really find much.   And then there was a morning where we were about ready to load up and send her to the NICU. And Kaetlin went and held her. And when she went and held her, she started breathing better.   And she calmed down. And it was kind of crazy. It was genuinely like the love of a mother.   Just like this connection seemed to just calm Hattie down. But we ended up finding out later, one of the nurses was amazing. And was like, I think that she has a broken collarbone.   They didn't see it on the x-ray at first because of the way her chin was turned. And so, when they went back and looked, they did another one. And sure enough, she did have a broken collarbone.   So, at the time, we kind of thought that was kind of the reason for her distressed breathing and that sort of thing. And she had trouble latching and sucking. And what we kind of came to find out later is she had what would be called hypotonia.   Which is basically where the best way to describe it in layman's terms is like a floppy baby. Like you hold her up and everything just kind of flops. And I remember Kaitlyn going to her four-month appointment.   And her being very concerned like, “Hey, Hattie's not meeting milestones. And I think that this isn't going to be a good appointment”. And sure enough, the doctor agreed.   We've always had amazing doctors around us. And so, he agreed. And so, we got referred to neurology.   And another just cool story about how God just provides. One of my best friends growing up, his dad was a neurologist in Birmingham. And so, I called him.   And he's like, all right, I got it. You're going to be here next Thursday. I'm like, oh, okay.   When we were kind of told like it's going to be like three or four months before we can even get you into a neurologist. And so, like God just kind of provided that. And we started that journey of trying to figure out what's going on.   And anyone who's ever had a special needs child, especially when you don't know what it is. Because there was nothing we could have done to foresee this happening. What Hattie had was called DeNovo, like just completely her.   Didn't come from me. Didn't come from Kaylin. And there's no other kids with special needs in our family.   It was just something we couldn't have expected or planned or could have even seen or anything like that. And so just kind of going through a lot of different doctors and tests and eventually getting referred to Johns Hopkins in Baltimore. Because at the time they thought it might be a neuromuscular thing.   And so, from there, they're like, oh, we don't think that's what it is. But then we ran a whole bunch of genetic panels. And like you're just going through all of that.   It definitely there's waves, right? Like it's like you want an answer, but at some level you're afraid of the answer. So, like each time we would do testing stuff before nothing would ever come back.   And so, it was like a relief. Okay, well, good. It's not that one.   Okay. Not that one. But then you're still like, well, what is it?   And so, after we went to Baltimore, they did much more extensive genetic testing. We found out she had this genetic disorder, or syndrome is what they're calling it now called GNV1. And it's crazy rare.   Like at the time, there were only 64 known cases. It was discovered in 2016. So, there's chances that there's other kids out there with it.   I think now there's a little over 100 that they know of. We're part of like a Facebook group where there's some of them in there. And so that's what we got the diagnosis for Hattie.   And so, what that means, I guess, probably no one knows what GNV1 is. Not even doctors. We go to doctors like, oh, can you tell us what this is?   We'll do our best. But it just starts out as hypotonia and global delay, which means every aspect of her is delayed from speech to gross and fine motor movements and all that kind of stuff. And also like with kids with special needs, it doesn't seem to affect any one of them the exact same way.   And so, but the thing about Hattie is like she has an infectious smile. She has this joy that is unreal. Like anybody that meets her just can't get enough of her.   And that is true in so many ways. Hattie uses a wheelchair to get around and Hattie's expressive language. So, her ways to communicate is behind.   But she understands everything. I mean, everything, which is pretty amazing, is my understanding. Not all the kids have that ability to receive and understand things as well as she does.   But she is an absolute joy. We used to always say and still do that Hattie's going to change the world. And we know the fact she's changed my world for sure.   And we know she's changed many others. But yeah, I could keep going on and on. But where we are today, like genuinely that she is a purpose and a reason why I've got to get up every single day.   Yeah. So, she's pretty amazing. Like I'm just yeah, I could go on and on about her.   Laura Dugger: (13:08 - 18:15) I think you described her so well with an infectious smile and joy is the word that comes to mind when you see her. Yeah. And now a brief message from our sponsors.   I want to say thank you to our longtime sponsor Chick-fil-A East Peoria. I hope that you've already downloaded the Chick-fil-A app. Because did you know that with the app you can skip the line and have food ready for you when you arrive?   This is one of my favorite options when I'm taking my four daughters to Chick-fil-A East Peoria. Download the Chick-fil-A app today and start earning points toward free rewards that are fully customized to your preferences and tastes. Chick-fil-A was named as one of Glassdoor's best places to work in the nation.   That's a huge honor. And one team member even wrote, no comparison. 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Another way to find it is simply type in donate to the search bar on our website and just click the first picture shown. We are all about sharing around here, sharing resources, sharing joy, and sharing the good news about Jesus Christ.   We ask that you also will share by sharing financially, sharing The Savvy Sauce podcast episodes, and sharing a five-star rating and review. You can also share any of our social media posts on Instagram or Facebook. We are grateful for all of it, and we just love partnering together with you. Now, back to the show.    In a different season, when many of us were in the midst of changing schedules and suddenly homeschooling our children in May of 2020, your family was receiving even more news. So, will you share that with us now as well?   James Jetton: (18:16 - 22:36) Yeah. We did have our fourth kid, Ryder. He was born in 2018, and he is a wild man.   My wife and I used to always say, or people would tell us, you'll know when you're done. But we had him, and we were like, okay, we're broke. We're done.   No more. But he's awesome. But yeah, the move forward to then, you know, that COVID stuff was really hard.   It was really hard. I was working for a church, and I do sports and rec ministry, and also I was doing student ministry at the time. And so, for me personally, like, things just kind of got shut down.   No one was doing sports leagues, and student ministry looked weirder than ever. And then my wife, she was working in the emergency room as a PA, and so she was facing everything head on. And so, I guess that kind of started in March.   It's funny, just to kind of back up a little bit. We felt prior to that, probably February or March of that 2020, when things were kind of like exploding, we just felt the Lord doing something in our lives. We felt like He was preparing us for something.   We felt like it was going to be something just amazing. But then as we moved forward to try to understand what God is doing, what He was telling us, in May, my 4-year-old, she had her preschool graduation. And I'll never forget this day.   My wife was a go-getter. She's tough. She's strong.   And we had a super weird COVID graduation for Isla, my 4-year-old. And it was weird because it was a drive-through graduation, so we had to get up there early and go do it. So, my wife also, she would do work night shifts so that she could be home with the kids when I couldn't be there.   And so, it wasn't uncommon for her to have to sleep in some. But this was like she hadn't worked the night before, and she hadn't worked. And so, we'd been off for two days, but she was just so exhausted.   She had this terrible headache that morning. And for her to say, like, I can't go to the graduation, that was like, there's something significant here. And I told her, like, she had gone to the doctor about a week before and got on some antibiotics, but it wasn't doing anything.   And I was just like, hey, I think it's time to go back to the doctor because you're not any better. And I've got to take these kids to this graduation. So, I loaded up all the kids.   We went to the drive-through graduation. While I was there, she called and said that her sister was going to take her to the emergency room. So that was a long day.   At that time, COVID was full on, so she couldn't have visitors. No one could come in with her. She had to be dropped off and go inside.   One huge plus in that for our specific situation is that she was taken to her own emergency room. So, she still had her friends and what she would call family there as well. And so, she dropped her off.   My sister-in-law dropped her off and just kind of waited in the parking lot until we figured out what was going on. So, it kind of went throughout that whole day. And I remember that night, the school was doing another virtual graduation where they showed pictures and that sort of thing.   And she texted me and said, I need to talk to you now. I was like, okay, like right now? Because I'm home alone with all four of the kids.   She's like, yeah, and I need you to get away from the kids. I was like, this doesn't sound good. What could this be?   And so, we FaceTimed, and that's where she told me they think I have leukemia. And so then as things started speeding up, we sent out a message to our church asking for prayers. From there, I put the kids to bed.   I drove to Pensacola. She got transferred to Pensacola, and we started treatment there for leukemia. So that was what happened.   That was the big moment in May. And then from there, there's a whole lot more. And so, I'll share as you wish.   Laura Dugger: (22:37 - 22:54) Wow. Thank you for catching us up to that point, James. I can't even imagine the initial devastation that comes.   And as your journey unfolds, I remember seeing a post about leaving your light on.   James Jetton: (22:54 - 24:24) Yeah. Like I said earlier, my wife always did the night shift. And so, I always left the light on for her when she was at work and then turned it off when she came home.   And so, yeah, so early on, I said that I'm not turning the light off until you come home. And so, during that time, the first treatment, it doesn't seem like a lot now because she was in the hospital so much. We didn't know how long she'd be in there.   But the first initial treatment, they're like, you're going to be in for three weeks. And so, I knew that she wouldn't be home for three weeks. And I guess this is me just kind of realizing that was a long time for the kids.   I remember talking to a friend of mine who was leading a small group of high school boys. And I remember him telling them, like, how hard do you think it would be if your mom was gone for three weeks? I was like, yeah, it's not easy.   But so. So, yeah, so that was that was the reason. Just like my wife, one, she was a light in the midst of all the darkness that she was having to face.   And I just wanted to make a point that like, hey, we're leaving this light on for you until you come home. And in a lot of respects, you know, she did go home. Long, long story.   But, yeah, that that was the reason for the light.   Laura Dugger: (24:25 - 24:34) So, well, and the way that you describe her, it sounds like our mutual friend April said her joy was just out of this world.   James Jetton: (24:34 - 24:36) Yeah, that's true.   Laura Dugger: (24:36 - 24:49) It sounds like maybe the both of you share that, but you were not entering into a joyful season. So, what did the next few months and year even look like?   James Jetton: (24:49 - 30:47) Yeah. So initially, when things went down, my wife and I agreed that we would not let our kids lose both their parents. And so, I tried to make it a point to be home at night.   So, when we were in Pensacola, like I would stay with her some nights, but I would also be home at night to put the kids to bed or I would put the kids to bed and I'd drive over that night and come back in the morning or be with her during the day. Like, you know, it was just crazy stuff. One, you know, it happened at the end of the school year.   So, we have all the kids at home. We didn't get to send them off to school. We were blessed to have an amazing college student.   It was one of Kaetlin's girls that she got to mentor when she was in high school. She was an amazing girl. She decided she would be like our nanny that summer.   And so, she was with our kids all day, every day. So, I could go and be with Kaetlin during the day and come home at night. And so, we went through that.   We were here and we did the treatment in Pensacola. It didn't work. And so, the next step at that point was like, well, what are we doing now?   And on a Thursday, the doctor was like, I think we need to go to MD Anderson. We'll see if there's a spot. And then on a Friday, they had a spot.   And then on Monday, we were in Houston at MD Anderson. I went to MD Anderson with her. You know, COVID protocol there still.   I could only be with her for 14 days and inpatient. And then I had to leave as an inpatient. So, I can only go with her for 14 days in that initial time.   And so, we went there. She started a treatment plan. We found an apartment.   And then I left. And then her dad came. And her dad was huge in a lot of this stuff and was able to allow us to do things like me and be with the kids.   And so, I think I stayed there for 10 days. And then he came over to stay with Kaetlin to take her back and forth to the hospital, just receiving treatment. And then I came home, and I came back to Niceville.   And that was during the summer. July, we were at home. We stayed in Niceville just kind of waiting to see, like, is Kaet going to be there longer?   Or is she going to be coming back here? And that was a wild summer. And this is what I think I would tell a lot of people that are going through hard things.   Like just because you're going through hard things doesn't mean there's other hard things. They're just a part of life. And, you know, when you have four kids, stuff happens.   You know, like we had one of my daughters, Isla, she had to have eye surgery that summer. While Kaet was in Houston. So that was an interesting thing.   My four-year-old son, he busted his head open on the back of a step going outside. So, he had to have some stitches in his head. He's the second that has had stitches in our family.   And he was the youngest. So, then the treatment, the goal was to get her to a place where she could do a bone marrow transplant. And so, we got, they got her to that point.   Her leukemia cell counts were low enough that we're ready to do a bone marrow transplant. And at that point, you know, we decided we're going to move to Houston. Everything was virtual at that time.   And I just couldn't see any reason why we couldn't all be together in Houston. And so, we found an apartment, we hunkered down. It's a two-bedroom apartment.   We built some makeshift bunk beds. And so, we moved there in August. And the community we have here was unreal.   The support that we have. Like I didn't, we didn't have to make a meal for, I felt like six months, I think. Like it was just crazy.   And people were allowing it and giving us money. So, we didn't have to worry about these kinds of things and what we're doing. And from moving packing boxes, like, I mean, I can't, it's just unfathomable.   All the different things that were put in place for us to do, to do what we did. And I don't think it would have happened without the community that came around us and our church here was great, but I've got to see The Big-C Church. And, and, and it was, it was amazing.   And so, we ended up, we all moved to Houston, and we lived in a two-bedroom apartment. Part of that story is like, you know, it's like, all right, we're doing this. And then talk about kids.   My four-year-old, the one that had also had the eye surgery, she had broken her ankle on a scooter. Like a week before we're going, it was like, are you kidding me? How is this happening right now?   But we had some great friends like, you know, when your wife is involved in the middle of the medical world, it makes access to doctors and stuff a lot easier when you're in a small town, like we are. So, they got it taken care of, got her in a cast. I was like, yeah, but we can't return with this hard cast.   We're going to Houston. He's like, all right, we'll get her in a hard cast. And we'll put her in a boot for the rest of the time.   So, we moved there. And you know, the dreams of like riding scooters around downtown Houston and doing all this kind of stuff kind of went away a little bit with the kid. And so, he, but there was a pool there.   So, we went swimming, she could swim. And so, we, we just made the best of what we had. Like we, we had a lot of good memories in that little apartment, even though it was, it was tough.   I remember, we, Halloween wasn't too long ago. We had our own little Halloween party in that apartment where we all dressed up, even Kaet. Cause she ended up getting her bone marrow transplant that time.   And another aspect of where dad was so important is when you get in the bone marrow transplant, you cannot leave, and you can have one guest. And so, her dad came and he stayed with her. It was about 30 days of bone marrow transplant.   And so, he was there with her so I could be with the kids, doing the best I can with that virtual school and, and managing Ryder and Hattie in the midst of trying to do school work with the kids. It's nothing I ever want to go back to.   Laura Dugger: (30:48 - 31:03) Well, and not to mention you appreciate The Big-C Church, but Houston was not your long-term community. So, being here in this new place and all of these transitions, what were the results of her bone marrow transplant?   James Jetton: (31:04 - 40:17) Yeah. So, the bone marrow transplant, it ended up working. She went into remission and so we get to come home Thanksgiving of 2020.   We came home and that was awesome. It was like a huge homecoming. Finally got back home.   She's, she's in remission. We felt like we'd beaten this. We, you know, we got that Christmas here and we were back home.   We even, our family always loves to go, has always gone to North Carolina for vacation every year. And we didn't get to do that. But so, it was like, now we're going.   And so, in January we're like, all right, we're going kids. It was just me and the kids and Kaet and we wanted to go see snow. So, we went up there and we found a place to stay.   It was an awesome trip. Loved it so much. We, when we had to check out of our place, we found another house so we could stay in for a few more days.   And so, you know, at that time though, when we were doing that, she was kind of having these red bumps kind of popping up over her. We didn't really know what it was. It could have been a reaction.   We couldn't figure it out. Saw some doctors here locally. No one could really figure out what it was.   And I think fast forward, what we found out probably, I think it was February. She came out of remission and that was kind of the beginning signs of her coming out of remission. And so that's where, life sped up.   Like, I mean, if it wasn't already fast, it was, it was just unreal. It was like a whirlwind like it was because she had to fly to Houston to go and see her doctors. And so, she was in Houston by herself when she found out that she had come out of remission, and they were going to start immediately.   So, she stays, and she flies over on Friday and on Monday they got her back doing her treatment. And so, and I was like, well, it looks like we're moving to Houston. And I was like, but this time we're not staying in a two-bedroom apartment.   It's like we're going to make this a little bit more manageable for us. So, we had some great family. Kaetlin actually had a cousin who lived in Houston.   We found a house inside their neighborhood that we could rent. And this was, you know, more, more provision that he just continued to show. We found this house in like a week and we had people from our community boxing up everything in our house.   He's gotten a truck, and we thought that we'd all get everything in one truck. But we didn't get everything in one truck. We'd even hired the movers to load up the truck.   They couldn't get it all in there. So, I was like, y'all told me that it would all fit on this truck, but now it's not. And it's Friday at like 5 p.m. when we were supposed to leave tonight. So, we're not leaving. But my brother came down. I had another one of my best friends come down and they were like, we got to go, we're going to make this happen.   So that next morning, I'm not kidding. When there was like 20 to 30 guys in my house, a brother had gotten the truck. I hadn't even, they left early to go with the truck.   I'd come. And I was at the house with the kids at a friend's house. And when me and the kids showed up, these 30 guys had already loaded up the truck and we were ready to go.   Guy came and dropped off a big spread of McDonald's for everybody. We prayed over us and we headed out that morning. And so, it was just, I mean, just crazy that, you know, in one week we packed up a four-bedroom house, loaded up two trucks and drove to Houston and we're now unloading at a new house in Houston.   And, and that's where we were for a while. That was where Kaetlin, then we went back into the treatment more aggressively trying to get her back to remission. And so that was, when we moved there in March of 2021.   And that was kind of our place for a while. We actually thought we'd be there for a real long time. Kids had started school there, trying our best to get connected community there, but it's difficult, especially when you've come from a place where you feel so connected and then you're moving somewhere new where you don't really know anybody.   And then you're moving there in a time where the whole town shut down. It was tough, but we got the kids back in school. We tried to start getting them back into normalcy of life.   And there's all these new trials when you're going through this stuff every day, it seems like there's a new trial. MD Anderson is amazing. They treat each patient. It's like an individual.   So, every plan they have is just specifically for that patient. And so, they were going to try to do this CAR T-cell treatment. So, we'd kind of gone through the whole summer, and then we get to the point where she's going to do her CAR T-cell treatment.   Now, you know, we, we were hunkered down with this COVID stuff. Like we didn't, we didn't do much. We got really good at DoorDash and grocery delivery.   And we, you know, we masked up everywhere we could because Kaetlin's system was so immuno-compromised and we had done what we had thought was a very good job of keeping her safe, keeping everyone safe. Well, and then she got to the point where she was ready to start this new trial with CAR T-cell treatment. And she gets admitted that night and every time they go in and they give her a COVID test, well, that night she had COVID.   And it was, it was like, what? And she didn't feel bad. Her dad had gotten it too.   Like we, and I, so I remember getting that, it was like one o'clock in the morning. I was asleep. I remember it like blowing up my phone.   And I was like, I didn't realize it until later. And I talked to her. And that was definitely a tough conversation because she had to like get moved, packed up and moved out and moved to a different place and then treatment for the COVID stuff.   But the crazy part was, and it was kind of, you know, I wanted to get frustrated about things I could, but like, she had zero symptoms and she had just tested positive. And so, the next morning we all had to go get tested. And it was just the weirdest thing.   I know that COVID has been so devastating to so many people. But in that moment for us, it was like, we don't like, I was like, I ran nine miles yesterday and now I'm positive for COVID. I don't.   And so, but what it did was it kicked her out of the trial that she was on. And so, then she had to come home. The next process was just kind of getting her ready for that same thing.   Basically, what her doctor did was like, I'm not taking out, you're going to get kicked off the trial, but I'm just going to make you my own individual patient. We're going to do it that way. And so, we had some, we had some pretty high hopes for this.   Doctor seemed pretty optimistic about this plan. And so, we had been renting our house in, in Niceville. And with this new plan, I would have had Kaetlin there for like three years.   And so, we were like, you know, do we really want to rent our house anymore? It's like, no, we don't. All right, well let's sell our house.   So, we sold our house, and it sold in like less than 24 hours. And it's like $25,000 over asking price. It was like, well, okay, God, I feel like that's what we're supposed to do.   And so, she went in to get that treatment. And, and, uh, unfortunately, uh, we found out that didn't work. Uh, it was like, well, she can't remember coming home and saying like, well, I'm ready.   I want to go back home. I was like, what? We just sold our house.   We don't have a home right now. But God always makes a way and you always provide always. Um, and so we, you know, I was like, all right, we want to go home.   We're going to go home. And at first I was being very logical. I was like, well, let's let the kids finish out the semester.   Cause this was like around Halloween is when she realized it didn't work and we're going to come home. So, we were able to come home. We had some amazingly generous friends who they got us a private flight to come home for that Halloween.   And I guess when we were there, um, that's where we really just decided we need to be back. And, and so she, when we went back to talk to her doctors about managing her leukemia remotely. And so that was what the plan was.   So we, we moved back that Thanksgiving, uh, with all of our stuff and we were looking for a place to stay. It was actually kind of a fun month. We were living on the beach for a couple months or really from Thanksgiving to right before Christmas.   We had some pretty awesome things come available. We were able to live in a house on the beach. And so that was, that was mine and my wife's always kind of like a special place.   And so, we love the water, and we love the beach. And so that was an awesome place for us to be. And so, uh, coming back, it was tough.   She was getting out of the hospital a lot just with fevers and stuff like that. And then we got to have Christmas here that December. And then January 9th of this past year, she, she, uh, eventually passed away.   We weren't expecting, I mean, we knew that there would be an end, but I don't think we could have expected it to, um, happen then. And I think we kind of thought we'd have a little bit more time, but we didn't, but we were thankful. I'm thankful for my wife.   It was like we got to get back now because we knew that when an issue did pass that we needed to be in our hometown and not in Houston, where our community was much smaller.   Laura Dugger: (40:18 - 40:27) So, yeah. And so, you're together, you're celebrating Christmas. And then things suddenly turned unexpectedly.   James Jetton: (40:28 - 40:28) Yeah.   Laura Dugger: (40:28 - 40:31) And that led to losing her on January 9th.   James Jetton: (40:32 - 44:59) Yeah. You know, nothing really happened like, you know, in that leukemia world. And you know, a lot of cancers that give you like, you know, a prognosis like, you have three months, you have four months full, but blood cancer is very different.   And it kind of exacts you and, and there's no way to really know for sure, like, is this going to work or how long do we have and that sort of thing. And she was just in and out of the hospital so much. When we came back home, when you have leukemia, anytime you have a fever above a hundred point four, it's like you're immediately going to the doctor.   And so that's kind of how, you know, when she went in, like, there's still kind of an expectation that she would come home. But then those last few days, like, I just, I vividly remember as we're trying to figure out what to do, we're going to, are we going to go to a new treatment plan or we're going to try something else? Or, or is this kind of the end?   And her doctor here, he said, there was a plan that we possibly could have done, but he was like, they're saying this got a success rate of like, whatever, nine of 10 people went into remission with it. He's like, but when you look closer, they were only in remission for four weeks. And he was like, is this what we want to do?   Cause chemo just, it wipes you out. And it's like, there's no way to continue to live like this. But she, Kaetlin, she was, she just had a way of bringing a peace over everybody.   She had a way of like knowing exactly what everyone needed, I guess, in some respects. Cause I remember leaving the day we decided we would not do the treatment plan. And I came home, like I said, I always try to be home to put my kids to bed.   She said that the night before it kind of, she went downhill fast. She got up and walked around the hospital with her dad and told her dad like, “Hey, I think I'm going to do, I think I'm going to do it. I'm going to do the treatment plan.”   You know, I've talked to him about this, but I feel like that was almost like the piece he needed to go home. You know, when she passed, it was like, it was beautiful. Like it was, it was such a blessing that she was in her home hospital and that the doors, it was like a revolving door.   I remember Kaetlin told me once, she said, “when I pass or when I'm in the last days, don't tell anyone that they can't come see me.” And so, we were trying to figure out how we're going to do this. And I was like, well, she said that anybody who wants to come see me, let them come see me.   And so, we put a word out and there was like a revolving door of people just coming in and out of the room all day. Like the doctors, the ER told the front desk people, like, you know, technically, I guess you're only supposed to have like two visitors or something because of the COVID things. And she was like, anybody that comes in and says they want to see Kaetlin Jetton, you say, “Go on up”.   So it was, it was pretty awesome seeing all these people come in and see her. And we had already gotten to see the impact that she had made on so many people's lives for the past couple of years, but it was cool to see them all there doing that. And I remember the night she passed, I leaned over, I was heading home and two of my best friends since the ninth grade had come down and they were at the house with the kids and I was coming home to put the kids to bed.   And I leaned over and gave her a kiss and I said, don't wait on me. It's like, it's okay. It's time to go home.   And sure enough, that's, I left that night and I got a phone call about 11 from her dad and she had passed and that, and I think that, you know, in some respects, it's like, should I have been there? I was like, but I think that also was like, no, Kaet wanted you to be with your two guys. And Kayla knew that her family would be there with her.   And she did exactly what she wanted to do. You know, she always had a plan even from her like celebration service. She had everything written out.   Who's going to speak, what songs are playing, when are we doing this? And so it was, it was, you know, it was pretty cool seeing how many people just came in and out and how she just kind of felt like she knew what she was doing, even up in the last days. So.   Laura Dugger: (45:00 - 45:55) Do you love The Savvy Sauce? Do you gain anything when you listen? Did you know that the two ways we earn money to keep this podcast live is through generous contributions from listeners and from our paying sponsors.   That means we can promote your business and you're still supporting The Savvy Sauce. It's a win-win. Please email us today at info@thesavvysauce.com to inquire about pricing for sponsoring each episode. Thank you for your consideration.    Well, James, your perspective is incredible. And yet I'm so sorry, such a deep loss for your whole family.   And what is life like now for all of your family these days? Cause it's still very recent. And I'm wondering if grief still comes up at unexpected times.   James Jetton: (45:56 - 50:49) Yeah. You know, it's, you know, it's a day-to-day thing, I believe. I don't, and grief is certainly something that sometimes you don't see it coming.   And I'll say, I love bragging on this community. I love bragging on this town so much. So, my kids, they're all in school, you know, and I'm bragging on my kids too.   After she passed, the kids got to stay home for a couple of weeks, but then it was time to go back to school. My two girls go to one school where actually Kaetlin went to school from kindergarten all through. So, I felt like that was a very special thing for her and the kids could go to the same school that their mom went to.   But then Hattie goes to a different school because of her special needs. And then Ryder goes to a different school. He's in preschool.   And so, after she passed, like, so it was complicated in the sense of, I've got to get Hattie to school at 7:30. I've got to get Lincoln out of school by like 8:45 and then Ryder can go in before 9:00 a.m. So, I would usually drop him off on the way. But I say, I'd say like, what does life look like?   Well, after she passed, I knew like, how am I going to make this work? And that semester, there was somebody in my house every morning at 7:00 a.m. to sit with the kids, help with breakfast, and help finish getting them ready while I could take Hattie to school at 7:30. And then I would come back home and after they finished getting ready, then I would take them to school. So, I had someone in my house every morning at 7:00 a.m. after she passed, which was, you know, they were doing it for the kids, but they were doing it for me too. I knew that I couldn't just lay in my bed and let people just come on in and take care of my kids. Like I had to get up, take a shower, look like I'm somewhat presentable and go on. And that's kind of how that last semester was, just community and people with meals and then through all that, trying to get them engaged, get them back into doing some things that they love to do.   And yeah, I like to brag on my kids in a lot of ways, this perspective kind of dawned on me in the past couple of weeks of like, I sent them back into a new school where they know very many people. Everybody knows them. Not everyone.   I don't know everybody. And they had to go and do that a few weeks after their mom passed. Here I am trying to stay away from people and not have a whole bunch of conversations, but yet the kids are stepping up and doing their thing.   And man, it's just, it's pretty inspiring when I think of it in that respect as well. Nowadays we are blessed that we get to have a nanny and it's, that's a whole cool story in itself. And that she worked with me in student ministry, and I'd actually left to go be a nanny for some other people in Nashville.   And I was texting her trying to figure out, “Hey, I need some help. You got any friends down here that want to be a nanny? Cause it's hard to find.”   And she's like, “Actually, I would love to come back and do it.” And that was just a huge blessing. Cause it was like, at the time of us having all these new things, I was able to be able to have somebody that the kids already knew come in and be there.   And so, she helps in so many ways and allows the kids to do their tennis and their soccer and gymnastics or whatever it may be. And it allows me to get to, coach them and be a part of that, those aspects of life, which I love doing so much. And so, she's really helped.   So, in our day to day now, like it, it's a lot of moving pieces. I mean, just last week, we got to go to a widower's retreat and there was never a worry, never worry about who's taking care of the kids, that they're getting to where they need to be. So, it's a genuine, like I get to see how a village truly takes care of the kids.   And yes, there are days and it's hard. And some days it just kind of sucks and it sucks for them. It sucks for me.   But I have gotten to see how God still shows out through the difficult moments and how he still provides no matter how far away I am or how close I am. He still continually provides. And I know that, and I know that he will not let us down.   It's one day at a time. And as we approach these new seasons, there's always new seasons. You talk about grief and things pop up.   I think that holidays will bring up stuff they already have in some respects and my wife, you know, she was a medical professional. So, when kids get sick, it's different now. We go to the doctor more often because mom's not here to take care of them and call in medicine.   But I think that we do sense a void in that when kids are sick and that sort of thing. But, today, like things are okay. We're doing all right.   Laura Dugger: (50:50 - 51:07) Well, and James, you were a journalism major and you're a very gifted writer. So where would you direct us to get to read more about your family and stay current and hopefully find ways that we can further support you?   James Jetton: (51:08 - 52:18) Well, my wife and I, we started a blog called Our Hands Go Up, and it's OurHandsGoUp.com. And that's formed out of, started with Hattie. That's where the blog started because Hattie, we talked about that joy that she has, but our hands will always go up.   Like her hands go up all the time and it just seems so appropriate. And the picture of hands going up, there's so many things that go to that with our praise to God, our vulnerability and our sides. And there's just a lot that comes through that anyway.   But yeah, Kaetlin started writing on that and I wrote some in that. She spearheaded it because she's way more organized and detailed than I am. So, it looks a lot prettier than what I would have done, but here recently, like I've felt a calling to bring it back and revitalize it.   So as of right now, like there's, my wife wrote a lot, and she still has writings that she never shared with anybody. So, I've started revitalizing it by sharing some of her writings, but I will be writing in there as well. So that would probably be a good place or even, and then my, just my social media, James Jetton, you can always see some crazy stories of my kids.   Laura Dugger: (52:21 - 52:34) Oh, wonderful. We will link to both of those in our show notes. And are there any practical needs that you do have at this time or any specific prayer requests you would like to share with us?   James Jetton: (52:35 - 53:26) You know, I think the specific prayer requests are just for me and for my kids. So, things are going to look different for them for sure. And I know there's going to be some hard moments.   So, I guess the prayer would just be, you know, provision as God's always provided. And, you know, when I say that, I don't just talk about it in like a material way, but like He seems to provide us with feelings, emotions, people, support, all of that. And so just provision for my kids and just encouragement and support for them as we've kind of walked through these, these new firsts for the kids and, and that it will just, they will still have, find the joy that we always talk about choosing and, and that my wife did so well that we will continue to find that joy through these more difficult days ahead for sure.   Laura Dugger: (53:26 - 53:58) Yes, Lord may it be so. Well, James, you clearly just have so much wisdom to share and I appreciate you walking through so much of your personal journey. And I know that you also do have a lighthearted personality and we're going to end on a lighter note because you may know that we're called The Savvy Sauce because Savvy is synonymous with practical knowledge.   And so, as my final question for you today, what is your Savvy Sauce?   James Jetton: (54:01 - 54:51) You know, my Savvy Sauce, it's just, it's one day at a time. I think that we get overwhelmed with, you know, I joke with people, like it's a stupid joke. But hey, if God wanted to give us more than one day at a time, He would. So, we only get one day, and He doesn't give us two days at one time.   You know, just taking things as they come one day at a time. We all have our goals. We all have our plans, our dreams and aspirations, but leaving space for the Holy Spirit and how God moves is critical.   And when you're walking through grief and you're walking through hard stuff, like thinking about too much out there in front of you can be debilitating. And so just focus on what your next step, just take one more step. We can always take one more step.   And so just kind of day at a time and just take one more step.   Laura Dugger: (54:52 - 55:08) James, thank you for your faithfulness to Kaet, your faithfulness to our Lord, your faithfulness to your children. And we will all be praying for each of you in this coming season and beyond. And just really grateful for you being my guest today.   James Jetton: (55:09 - 55:26) Well, I'm really grateful to be here. This is great. I'm thankful for the chance to just share her story and share our story.   I feel God has just moved and worked through us in so many amazing ways. And anytime I can get a chance to share how God has moved and worked, I'm thankful. So, thank you for having me.   Laura Dugger: (55:26 - 58:42) It's been an honor. One more thing before you go. Have you heard the term gospel before?   It simply means good news. And I want to share the best news with you. But it starts with the bad news.   Every single one of us were born sinners, but Christ desires to rescue us from our sin, which is something we cannot do for ourselves. This means there is absolutely no chance we can make it to heaven on our own. So, for you and for me, it means we deserve death and we can never pay back the sacrifice we owe to be saved.   We need a savior. But God loved us so much, he made a way for his only son to willingly die in our place as the perfect substitute. This gives us hope of life forever in right relationship with him.   That is good news. Jesus lived the perfect life we could never live and died in our place for our sin. This was God's plan to make a way to reconcile with us so that God can look at us and see Jesus.   We can be covered and justified through the work Jesus finished if we choose to receive what He has done for us. Romans 10:9 says, “That if you confess with your mouth Jesus is Lord and believe in your heart that God raised him from the dead, you will be saved.” So, would you pray with me now?   Heavenly Father, thank you for sending Jesus to take our place. I pray someone today right now is touched and chooses to turn their life over to you. Will you clearly guide them and help them take their next step in faith to declare you as Lord of their life?   We trust you to work and change lives now for eternity. In Jesus' name we pray. Amen.   If you prayed that prayer, you are declaring him for me, so me for him. You get the opportunity to live your life for him. And at this podcast, we're called The Savvy Sauce for a reason.   We want to give you practical tools to implement the knowledge you have learned. So, you ready to get started? First, tell someone.   Say it out loud. Get a Bible. The first day I made this decision, my parents took me to Barnes & Noble and let me choose my own Bible.   I selected the Quest NIV Bible and I love it. You can start by reading the book of John. Also, get connected locally, which just means tell someone who's a part of a church in your community that you made a decision to follow Christ.   I'm assuming they will be thrilled to talk with you about further steps, such as going to church and getting connected to other believers to encourage you. We wa

Join Nick Lamagna on a special BONUS episode of The A Game Podcast with our guests Jackson and Shaun Amiruddin, a father and son telling an inspiring story of how Jackson survived acute lymphoblastic leukemia at a very early age.  He is now getting the word out with a special fundraiser to bring a cure and awareness for this cause to stop families and children from suffering through Hope Chasers as he is looking for all of us to help.   There is a current campaign running for the Student Visionary of the year where Jackson is looking for donations.  We are proud to help promote a part of the Leukemia & Lymphoma Society's (LLS) Student Visionaries of the Year Campaign, working to raise as much as possible for LLS's mission as a global leader in the fight against blood cancer, LLS:  Help will go toward: Funds cutting-edge research leading to breakthroughs in immunotherapy, genomics and personalized medicine that are improving and saving the lives of patients Provides free education and support for blood cancer patients and families, including personalized, one-on-one support, assistance with identifying and enrolling in clinical trials, and more. Mobilizes thousands of advocates to drive policy changes that accelerate the development of new cancer treatments and break down barriers to care. Please consider joining this fight by making a donation. All donations are greatly appreciated and tax-deductible. Please visit my website often and tell friends who would also like to donate! Topics for this episode include: ✅ Amazing story of how a child beat Leukemia  ✅ Words of encouragement from a child to other kids suffering from illness today ✅ Advice for parents struggling with the stress and emotions of dealing with this situation ✅ Tips on how to pick the best doctor when emotions are on the line. ✅  How we can help save lives  + More See the show notes to connect with all things Hope Chasers! Connect with Hope Chasers: Hope Chasers Facebook Hope Chasers Instagram Student Visionary of The Year Fundraiser Follow Jackson Amiruddin on Instagram --- Connect with Nick Lamagna www.nicknicknick.com Text Nick (516)540-5733 Connect on ALL Social Media and Podcast Platforms Here FREE Checklist on how to bring more value to your buyers