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In this podcast, Max S. Topp, MD, and Pier Luigi Zinzani, MD, PhD, explore the current and future implications of some of their top choices of studies in lymphomas and ALL presented at the EHA and ICML 2025 meetings.Program Abstracts: POLARGO: Rituximab, Gemcitabine and Oxaliplatin ± Polatuzumab Vedotin for R/R DLBCLECHO: Rituximab-Bendamustine ± Acalabrutinib in Untreated High-Risk MCLCADANCE-101: BGB-16673 BTK Degrader in R/R CLL/SLLInMIND: Tafasitamab, Lenalidomide, Rituximab in R/R FLSHR2554: Oral EZH2 Inhibitor in R/R PTCLSYRUS: AZD0486 Bispecific Antibody for R/R B-ALLPresenters:Max S. Topp, MDHead of Hematology and Clinical CAR-T Program LeadAssociated ProfessorMedinische Klinik und Poliklinkik IIUniversity of WurzburgWurzburg, GermanyPier Luigi Zinzani, MD, PhDProfessor of HematologyAlma Mater Studiorum- University of BolognaHead, “Seràgnoli” Institute of HematologyIRCCS Azienda Ospedaliero-Universitaria di BolognaDepartment of Medical and Surgical SciencesBologna University School of MedicineBologna, ItalyLink to full program:https://bit.ly/4obcJPI
Gedit, Gedit Friday! What would you do if you were a billionaire?... Flash house?, Help the issues of the world?, Retire your family?... Well the boys know what they'd do... Matua Marc came to the show a little while ago with his segment "Shell We" a chance for Shifters to share something they were proud about, their story, their rise through trials and tribulations, a safe place... Well a Shifter who wrote in back then, now has an update for us all... One that made the boys reflect... Deano Collins is not only a friend of the show but come the 5th of September, he is doing some unbelievable mahi... He is spending 24hrs going up against a boxing bag to raise funds and awareness for the Child Cancer Foundation as his Son Houston was diagnosed with Leukemia in 2023... Hit that link below to stay caught up with anything and everything TMS. www.facebook.com/groups/3394787437503676/ We dropped some merch! Use TMS for 10% off. Here is the link: youknowclothing.com/search?options%5Bprefix%5D=last&q=tms Thank you to the team at Chemist Warehouse for helping us keep the lights on, here at The Morning Shift... www.chemistwarehouse.co.nz Learn more about your ad choices. Visit megaphone.fm/adchoices
In this week's episode, we'll learn about a JAK inhibitor to prevent complications of CD19-directed CAR T-cell therapy. In a phase 2 study, itacitinib was well tolerated and demonstrated promising reductions in the incidence of cytokine release syndrome and neurotoxicity. After that: investigators report direct interactions between ChAdOx1 and platelets under arterial shear conditions. Investigators say it's a novel biophysical mechanism that potentially contributes to post-vaccination arterial thrombosis. Finally, we explore lineage switch, an emerging form of acute leukemia relapse with dismal outcomes. It arises rapidly following antigen-targeted immunotherapy, highlighting the importance of advanced methods for detection and treatment.Featured Articles: Itacitinib for the prevention of IEC therapy–associated CRS: results from the 2-part phase 2 INCB 39110-211 studyShear-dependent platelet aggregation by ChAdOx1 nCoV-19 vaccine: a novel biophysical mechanism for arterial thrombosisProject EVOLVE: an international analysis of postimmunotherapy lineage switch, an emergent form of relapse in leukemia
Welcome to episode 201 of Sports Management Podcast. Today's guest is Geoff Thomas MBE – A former professional footballer, cancer survivor and a Patron of charity for Cure Leukaemia. When this episode is live, he just completed all the 21 stages of the Tour the France, raising vital funds for Cure Leukaemia, a cause close to his heart having overcome chronic myeloid leukaemia himself. We spoke about: His background as a professional footballer 9 caps with England without losing Being diagnosed with leukaemia and getting 3 months to live Giving back through charities How Arthrosamid® helped with his knee pain And much more! Time stamps: 00:03 Guest Background & Football Career 03:09 Cancer Diagnosis & Treatment Journey 09:51 Sports Mindset Application to Cancer Treatment 11:54 Tour de France Charity Challenge 15:00 Cure Leukaemia Charity Evolution 19:46 Physical Challenges & Recovery Strategy 21:22 Arthrosamid Knee Treatment 27:09 Mental Health & Support Advice 31:58 Future Goals & Network Follow Sports Management Podcast on social media Instagram Twitter LinkedIn YouTube www.sportsmanagementpodcast.com
In this week's episode we'll learn more about the use of ruxolitinib plus dexamethasone to treat newly diagnosed patients with adult hemophagocytic lymphohistiocytosis; lysine-specific demethylase-1 inhibitors as a potential new class of therapies for sickle cell disease and other beta-globinopathies; and insights into clinical characteristics of patients with von Willebrand factor levels that are lower than normal but higher than those typically used to diagnose von Willebrand disease.Featured Articles:Ruxolitinib combined with dexamethasone for adult patients with newly diagnosed hemophagocytic lymphohistiocytosis in ChinaNovel, potent, and orally bioavailable LSD1 inhibitors induce fetal hemoglobin synthesis in a sickle cell disease mouse modelClinical phenotype and pathophysiological mechanisms underlying qualitative low VWF
On this Make A Difference Minute, teenager Lincoln Kallas of Hartselle, Alabama, shares a powerful glimpse into his journey battling leukemia and how the care he received at St. Jude Children's Research Hospital—and the support from his community—helped him through. From hospital stays to a surprise message from a Tennessee Vols player, Lincoln's story reminds us that even in the darkest moments, hope and encouragement can make all the difference. Sponsor: Premier Structures PremierStructures.com
In this episode, Associate Editor Dr. Philippe Armand discusses the Review Series on mantle cell lymphoma with author Dr. Christine Ryan. Both were authors of "Frontline management of mantle cell lymphoma", and discuss shifts in treatments and new research.Find the full review series in Volume 145 Issue 7 of Blood: "Review series on mantle cell lymphoma: sands shifting in the darkness"
Are you ready to kick up your heels to some great music and raise funds for a great cause? Then don't miss the 13th annual Kickin For A Kure this Saturday, July 19! It takes place from 2:30 p.m. to midnight in the Freeman Coliseum Expo Hall in San Antonio and includes a three-hole, double-elimination washer tournament, live music by top-name entertainers, a live auction, prize drawings, and more. This much-anticipated annual event, held on the third Saturday of July, is hosted by the DM Foundation to raise awareness and funds for the Leukemia & Lymphoma Society– South Central Texas....Article Link
F-Stop Collaborate and Listen - A Landscape Photography Podcast
In this episode of F-Stop Collaborate and Listen, host Matt Payne chats with photographer Geoffrey Giebelhaus about the Fediverse—a decentralized network of social media platforms like Mastodon and PixelFed that offer an alternative to the algorithm-driven, ad-heavy giants like Instagram and Facebook. Geoffrey breaks down what the Fediverse is, how it works, and why it's a great fit for photographers seeking a more ethical, community-focused space to share their work. The conversation covers the learning curve of moving to decentralized platforms, the importance of hashtags and alt text, tips for getting started, and how the Fediverse empowers users to keep their followers and content, no matter where they go. They also touch on the deeper creativity and connections fostered by this new social media landscape, and close with Geoffrey's advocacy for the Leukemia and Lymphoma Society of Canada. If you're fed up with mainstream social media and want to learn about a more authentic and user-driven alternative, this episode is for you. Links: Geoff's awesome blog about the Fediverse Support the podcast on Patreon Join my newsletter The Leukemia & Lymphoma Society
Send us a textJonathan Daige is an Army veteran with two deployments to Iraq. A retired Worcester Police officer of 18 years and served 8 years on the SWAT Team as a sniper. Within that time he has battled testicular cancer that spread all over his body from his chest to his brain multiple times. After cycling to heal he began a nonprofit Thin Blue Ride that helps military veterans, first responders and their families when battling cancer. Since 2017 Thin Blue Ride has raised over $800,000 for families across the country. JD now medically retired has been battling Leukemia for several years and is continuing to help cancer warriors whenever he can. Find Jonathan DaigeWebsiteFind The Suffering PodcastThe Suffering Podcast InstagramKevin Donaldson InstagramTom Flynn InstagramApple PodcastSpotifyYouTubeThe Suffering Podcast FamilySherri AllsupSupport the showThe Suffering Podcast Instagram Kevin Donaldson Instagram TikTok YouTube
In this week's episode, we'll learn about rapid, high-sensitivity diagnostic assays for TTP, or thrombotic thrombocytopenic purpura, that can reduce unnecessary treatments. After that: enhancing PD-1 blockade in relapsed/refractory extranodal NK/T-cell lymphoma. In a single-arm, phase 2 study, combined CD38 and PD-1 inhibition demonstrated durable responses and manageable safety. Finally, a lymphoma horror story with a happy ending. CREBBP mutations create a zombie enzyme that competes with its wild-type counterparts. By enforcing CD40 signaling, a bispecific antibody overcomes this effect and induces lymphoma cell death.Featured Articles:Rapid ADAMTS13 activity assays for thrombotic thrombocytopenic purpura: a systematic review and meta-analysisEfficacy of combined CD38 and PD-1 inhibition with isatuximab and cemiplimab for relapsed/refractory NK/T-cell lymphomaBlunted CD40-responsive enhancer activation in CREBBP-mutant lymphomas can be restored by enforced CD4 T-cell engagement
ICYMI, this hot take episode originally aired in April of this year. One of America's most notorious TV moms sat down with me and gave me a great interview. Barbara Bregoli, the mother of Danielle Bregoli, famously known as Bhad Bhabie or the "Cash Me Outside" girl. Barbara shared her life story, from her Brooklyn upbringing and career in finance to the challenges of being a single mother. She opened up about the infamous Dr. Phil appearance, clarifying misconceptions and discussing Bhad Bhabie's evolution into a rapper. Barbara also revealed her personal battles with breast cancer and the impact on her family, as well as the recent news of Dani's leukemia diagnosis. Through it all, Barbara's resilience and unwavering support for her daughter shone brightly, offering a deeply personal and inspiring narrativeTimestamps:00:00:00 - Introduction and Guest Welcome00:00:20 - Barbara Bregoli's Background and Dr. Phil Appearance00:00:50 - The Origin of "Catch Me Outside" Phrase00:28:03 - Bhad Bhabie's Leukemia Diagnosis00:30:36 - Alabama Barker Feud, Bhad Bhabie's OF earnings and more00:35:17 - The Kardashian's, Bhad Bhabie's future goals and moreMY Go Big Podcasting Courses Are Here! Purchase Go Big Podcasting and learn to start, monetize, and grow your own podcast. Use code DAD15 for 15% OFF until 6/30/2025**SHOP my Amazon Marketplace - especially if you're looking to get geared-up to start your own Podcast!!!**https://www.amazon.com/shop/thesarahfrasershowShow is sponsored by:ASPCA Pet Insurance to explore coverage, visit A-S-P-C-A pet insurance dot com slash TSFS.Horizonfibroids.com get rid of those nasty fibroidsNutrafol.com use code TSFS for FREE shipping and $10 off your subscriptionQuince.com/tsfs for FREE shipping on your order and 365 day returnsRula.com/tsfs to get started today. That's R-U-L-A dot com slash tsfs for convenient therapy that's covered by insurance.Thrivecosmetics.com/tsfs Brighten a mom's day—especially if you're that mom. Go to thrivecausemetics.com/TSFS for 20% OFF your orderFollow me on Instagram/Tiktok: @thesarahfrasershow ***Visit our Sub-Reddit: reddit.com/r/thesarahfrasershow for ALL things The Sarah Fraser Show!!!***Advertise on The Sarah Fraser Show: thesarahfrasershow@gmail.comGot a juicy gossip TIP from your favorite TLC or Bravo show? Email: thesarahfrasershow@gmail.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Do we have another comet visiting from outside the solar system? What is Oumuamua? Is the Ring of Fire amping up in activity? Is leukaemia genetic? Does exposure to certain chemicals increase your risk of cancer? Why are early health screenings so important? How do you measure the risk of certain health treatments? Dr Chris Smith and Clarence Ford have all the answers... Like this podcast? Please help us by supporting the Naked Scientists
Do we have another comet visiting from outside the solar system? What is Oumuamua? Is the Ring of Fire amping up in activity? Is leukaemia genetic? Does exposure to certain chemicals increase your risk of cancer? Why are early health screenings so important? How do you measure the risk of certain health treatments? Dr Chris Smith and Clarence Ford have all the answers... Like this podcast? Please help us by supporting the Naked Scientists
Patty Furco's then 4 year old daughter Abby was diagnosed with Pre B Cell Acute Lymphoblastic Leukemia in 2011, a diagnosis which was changed 2 weeks later to Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia. This diagnosis reduced Abby's chances of survival to 20 percent. Patty will talk about the 10 years that Abby was able to somehow survive this very difficult form of Leukemia, which included her doctors saying that she had 48 hours to live in May of 2016. Patty and her husband very sadly began to make funeral arrangements and as Abby's time was supposedly nearing its end, somehow she recovered and was able to live another 5 years until her passing in October of 2021.
In this week's episode we'll learn more about a novel mouse model that recapitulates many of the properties of human sickle cell SC disease; results from the induction phase of the risk-adapted MIDAS trial of isatuximab, carfilzomib, lenalidomide, and dexamethasone in newly diagnosed, transplant-eligible multiple myeloma; and a link between splicing factor mutations and competitive fitness in myelodysplastic syndrome stem cells.Featured articles:A novel mouse model of hemoglobin SC disease reveals mechanisms underlying beneficial effects of hydroxyureaIsatuximab, carfilzomib, lenalidomide, and dexamethasone induction in newly diagnosed myeloma: analysis of the MIDAS trialCell-autonomous dysregulation of interferon signaling drives clonal expansion of SRSF2-mutant MDS stem/progenitor cells
Elaine Cooney joined PJ to talk about her cousin Aisling — a devoted young Mam who's now fighting leukemia with everything she has. Support Aisling here Fundraiser by Deborah Elaine : Help Aisling Thornhill on her journey with Leukemia Hosted on Acast. See acast.com/privacy for more information.
In this episode of the Braun Performance & Rehab Podcast, Dan is joined by Alexa Degan to discuss her recovery from 2 ACL injuries. Alexa Degan is a resilient and driven ice hockey player currently competing at the collegiate level for Long Island University. A 2023 graduate of Morristown-Beard School, Alexa played four standout seasons of varsity hockey, helping her team secure three state championships and one co-championship. Over her freshman and sophomore seasons, she tallied seven goals and 25 assists, earning first-team all-state honors before overcoming the challenge of two ACL injuries that sidelined her.In addition to hockey, Alexa competed in two varsity lacrosse seasons and demonstrated strong leadership off the field as well. She co-captained a fundraising campaign that raised an impressive $122,000 for the Leukemia & Lymphoma Society, showcasing her commitment to making a broader impact.Alexa is the daughter of Christa and Sean Degan and has two brothers, Justin and Ayden. Her story is one of perseverance, leadership, and dedication—both on and off the ice.For more on Alexa, be sure to follow @torn2triumphant*SEASON 6 of the Braun Performance & Rehab Podcast is brought to you by Isophit. For more on Isophit, please check out isophit.com and @isophit -BE SURE to use coupon code BraunPR25% to save 25% on your Isophit order!**Season 6 of the Braun Performance & Rehab Podcast is also brought to you by Firefly Recovery, the official recovery provider for Braun Performance & Rehab. For more on Firefly, please check out https://www.recoveryfirefly.com/ or email jake@recoveryfirefly.com***This episode is also powered by Dr. Ray Gorman, founder of Engage Movement. Learn how to boost your income without relying on sessions. Get a free training on the blended practice model by following @raygormandpt on Instagram. DM my name “Dan” to @raygormandpt on Instagram and receive your free breakdown on the model.Episode Affiliates:MoboBoard: BRAWNBODY10 saves 10% at checkout!AliRx: DBraunRx = 20% off at checkout! https://alirx.health/MedBridge: https://www.medbridgeeducation.com/brawn-body-training or Coupon Code "BRAWN" for 40% off your annual subscription!CTM Band: https://ctm.band/collections/ctm-band coupon code "BRAWN10" = 10% off!Ice shaker affiliate link: https://www.iceshaker.com?sca_ref=1520881.zOJLysQzKeMake sure you SHARE this episode with a friend who could benefit from the information we shared!Check out everything Dan is up to by clicking here: https://linktr.ee/braun_prLiked this episode? Leave a 5-star review on your favorite podcast platform
In this powerful episode of the Medical Sales U Podcast, I sit down with Nick Rich—cancer survivor, AYA advocate, and now a Senior Oncology Account Specialist at Pfizer. Nick opens up about his deeply personal journey from battling cancer to building a career in oncology sales, where he now helps bring life-saving treatments to patients fighting the very diseases he once faced.We discuss how his diagnosis shaped his purpose, the pivotal moments that led him into medical sales, and how his fundraising team helped raise over $50,000 for the Leukemia and Lymphoma Society. You'll hear the grit behind his transition from patient to professional, and how he channels his pain into purpose every day on the job.Whether you're in sales, healthcare, or simply looking for inspiration, this conversation will move you. Nick's story is a testament to resilience, faith, and the impact of using your story to serve others.
Will Yank is a 2020 graduate from Wabash College who is also a member of Phi Gamma Delta Fraternity. At 21 years old, he was diagnosed with leukemia and septic shock, and now he speaks on reclaiming hope, something that is a very important lesson for us all to consider when life throws us a curveball and we start to feel pain, failure, or regret. Today we're going to hope for something. In episode 581 of the Fraternity Foodie Podcast, we find out why Will decided on Wabash College, what made him want to join Phi Gamma Delta Fraternity, what it was like to be diagnosed with leukemia and septic shock at 21 years old, why hope is more than just a “feel-good” emotion, why having a future vision so important for college students today, what we can do for students who feel like they have no one to lean on, how students can turn past pain, failure, or regret into a teacher instead of a burden, how to support members going through difficult mental health or life challenges, what is one action students can take right now to reclaim a sense of hope, and what his legacy will be for this generation of college students. Enjoy!
In this week's episode, we'll learn about using AI to assess transplant risk in myelofibrosis. In a step toward personalized medicine, researchers report on a machine learning model that identifies 25% of patients with poor outcomes. After that: preventing priapism in men with sickle cell anemia. A recent phase 2 feasibility study shows high rates of recruitment, retention, and adherence to oral therapies, coupled with a significant reduction in the risk of this difficult complication. Finally, new research indicates that hallmarks of terminal T-cell exhaustion are absent in multiple myeloma, from diagnosis through maintenance therapy. We explore these provocative and counterintuitive findings arising from profiling of blood and marrow samples.Featured Articles:Use of machine learning techniques to predict poor survival after hematopoietic cell transplantation for myelofibrosisA controlled trial for preventing priapism in sickle cell anemia: hydroxyurea plus placebo vs hydroxyurea plus tadalafilHallmarks of T-cell exhaustion and antigen experience are absent in multiple myeloma from diagnosis to maintenance therapy
When Laura's daughter was diagnosed with leukemia, her world stopped. What followed was a powerful journey through fear, resilience, and fierce advocacy. In this episode, Laura DeKraker Lang-Ree—a lifelong educator and now author of The Cancer Parent's Handbook—opens up about the most terrifying day of her life, how she transformed pain into purpose, and why parent-to-parent support is critical in the childhood cancer community. Her reflections are raw, heartfelt, and offer wisdom for every parent facing a medical diagnosis with their child.
Cedar Connell was 15 years old when he found himself on his way to Lurie Children's Hospital in Chicago to begin his treatment for B Cell Acute Lymphoblastic Leukemia in 2022. Cedar and his mom Kiki will talk about the difficult treatment that he went through, including his move from Chicago to the Dana Farber Cancer Institute in Boston in 2023. Cedar is now getting ready to do his part for the Leukemia and Lymphoma Society as TEAM CONNELLSLLS will be getting ready for a 31 day challenge beginning on July 1st and ending on August 1st to exercise 3 miles each day for that time period, in the hope that they raise 35,000.
Omg Bravo Bosses! I interviewed Jared Lipscomb from The Valley and so we are skipping our typical reality roundup up today in favor of this interview which was chock FULL OF TEA! You can watch this episode on YouTube! If you don't know Jared, you're about to. Jared started off as the makeup artist for the Vandercrew and became a stable fixture in the lives of the cast members as they progressed to The Valley. Since Jared has been around for many years, he knows the truth about our favorite Bravo stars that we love to hate and he's ready to TELL ALL! We talked about Zach's demonic words that couldn't be said on tv, why he is furious at some cast members for being in the comments, what Dark Side Danny REALLY looks like as well as where the fans have it wrong about Janet. We also get into Jared's fascinating backstory in drag and in makeup, we talk about his cancer journey and lastly, Jared tells the story of how he was integrally involved in Britney Spears' conservatorship battle! Follow Jared on IG @jaredlips and Listen to This Side of the Hill wherever you get your podcasts! For more information on participation in and donations for Leukemia and Lymphoma follow: @llsusa and @nmdp_org Thank you to our SPONSORS! Petscosset - Use code: GS15 for 15% off any product! Doodle - Doodle is a user-friendly scheduling platform that helps individuals and teams easily find meeting times, book appointments, and organize events. For a limited time, get 20% off here with CODE: AFFILIATE-20. Rubbish Home - Rubbish makes garbage bags that make trash less day less painful and more enjoyable.We've made your garbage bag dreams come true with our 13-gallon trash bags. Each box includes a fun saying and a reminder when you're low on garbage bags. Our compostable, non-toxic, and PFAS-free trash bags break down quickly and 10% of our garbage bags go to charity. Rubbish does everything your current garbage bags don't! You can purchase my new RE-BRANDED The Bravo Investigator Merch here! Subscribe to Hurrdat Entertainment's YouTube Channel for full length video episodes! Follow me on Instagram: @thebravoinvestigator Follow me on Tik Tok: @thebravoinvestigator Email me your questions or suggestions: Brunchandbravo@gmail.com This is another Hurrdat Media Production. Hurrdat Media is a podcast network and digital media production company based in Omaha, NE. Find more podcasts on the Hurrdat Media Network by going to HurrdatMedia.com or the Hurrdat Media YouTube channel! Learn more about your ad choices. Visit megaphone.fm/adchoices
In this week's episode, we'll learn more about social determinants of health that impact access to allogeneic hematopoietic cell transplantation in patients with acute myeloid leukemia, or AML; use of megakaryocyte growth factor receptor-based stem cell depletion as part of pretransplant conditioning in ex vivo autologous gene therapy; and identification of an eight-protein risk signature as well as a novel single protein biomarker, soluble oncostatin M receptor, for risk stratification in AML.Featured Articles:Social Determinants of Health and Access to Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid LeukemiacMPL-Based Purification and Depletion of Human Hematopoietic Stem Cells: Implications for Pretransplant ConditioningBlood-Based Proteomic Profiling Identifies OSMR as a Novel Biomarker of AML Outcomes
In today's episode, we had the pleasure of speaking with Alexey Danilov, MD, PhD, about current challenges and emerging treatment approaches for the management of leukemia and lymphoma that were published in a manuscript based on proceedings from the inaugural Bridging the Gaps in Leukemia, Lymphoma, and Multiple Myeloma Conference. Dr Danilov is the Marianne and Gerhard Pinkus Professor of Early Clinical Therapeutics, medical director of the Early Phase Therapeutics Program for the Systems Clinical Trials Office, co-director of the Toni Stephenson Lymphoma Center, and a professor in the Division of Lymphoma in the Department of Hematology & Hematopoietic Cell Transplantation at City of Hope in Duarte, California. In our exclusive interview, Dr Danilov highlighted recent advances and controversies in the treatment of select patients with hematologic malignancies. He noted chemotherapy-free regimens that are shifting treatment paradigms in mantle cell lymphoma, preferred and emerging BTK inhibitors for the management of chronic lymphocytic leukemia, and the evolution of CD19-directed CAR T-cell therapies for diffuse large B-cell lymphoma. Dr Danilov concluded by taking a forward glance at future developments like BTK degraders and novel CAR T-cell therapy targets.
Blood editor Dr. Laurie Sehn discusses the topic of "Aggressive non-Hodgkin lymphoma: defining and managing high-risk subsets" featuring Drs. Mark Roschewski, Grzegorz Nowakowski, and Neha Mehta-Shah, who each contributed to the articles featured in the review series on high-risk aggressive lymphoma.See the full review series on high risk lymphoma in volume 144, issue 25 of Blood.
In this incredible episode of Marrow Masters, we sit down with Kayla West, a stem cell donor from Texas, and Miriam Bauer, the mother of a young leukemia survivor Miley, from Oklahoma. This story is a deeply emotional journey of hope, resilience, and a connection that transcends bloodlines. Kayla and Miriam take us through the entire transplant process from both perspectives: the donor stepping up during a pandemic, and the caregiver navigating a life-threatening diagnosis in a child.We begin with Kayla's decision to join the donor registry after a chance encounter with DKMS at a Goo Goo Dolls concert. She didn't expect to be called to donate, but when she was, during COVID lockdown, she jumped at the chance to help someone—anyone—in need. That “anyone” turned out to be Miley, an eleven-year-old girl who had been diagnosed with acute myeloid leukemia (AML) and urgently needed a transplant after two brutal rounds of chemotherapy.Miriam recounts those terrifying early days at St. Jude, from the moment of diagnosis through the chaos of the early pandemic lockdowns. She was Miley's only caregiver during a 248-day hospital stay. Her story is filled with moments of heartbreak and triumph, from failed chemo rounds to the joy of reaching remission and finding a viable donor in Kayla. We learn how transplant coordination works, how donor cells were frozen and shipped during COVID, and how little details—like celebrating donor day or choosing a transplant date that coincides with family birthdays—brought joy in dark times.Post-transplant, Miley's life has been a mix of recovery and lingering health effects, but she's thriving. Miriam emphasizes advocacy, honesty, and self-care for caregivers. Kayla, for her part, reflects on the overwhelming emotion of learning she was a match, undergoing all the testing during COVID, and then finally meeting the recipient of her cells in an unforgettable reunion in New York. The two families, now bonded for life, meet regularly and have built a deep friendship. Next up: A trip for Kayla's family to Oklahoma to experience a powwow with Miriam, Miley, and their family!The videos below will have you reaching for the tissues and hopefully inspire many to get swabbed.Kayla also shares her decision to launch a nonprofit, SETX Leukemia Organization, focused on educating communities and recruiting new donors. Her goal is to prevent other families from facing what Miriam's did—wondering if there will be a match in time. Kayla's drive, born from her experience, continues to ripple outwards as she recruits more potential donors at local events with DKMS support.This episode isn't just about survival—it's about connection, purpose, and what can happen when strangers become family through an act of extraordinary generosity.SETX Leukemia Organization (Kayla's nonprofit): https://setxleukemia.org/DKMS (Be The Match partner organization): https://www.dkms.orgDKMS Video about Kayla, Miley, and Miriam: https://www.youtube.com/watch?v=sNhwRxXMbw8Thanks to our Season 17 Sponsors:Leukemia and Lymphoma Society (LLS): https://lls.org/and Incyte: https://incyte.com/ National Bone Marrow Transplant Link - (800) LINK-BMT, or (800) 546-5268.nbmtLINK Website: https://www.nbmtlink.org/nbmtLINK Facebook Page: https://www.facebook.com/nbmtLINKFollow the nbmtLINK on Instagram! https://www.instagram.com/nbmtlink/The nbmtLINK YouTube Page can be found by clicking here.To participate in the GVHD Mosaic, click here: https://amp.livemosaics.com/gvhd
This episode of Marrow Masters brings us an incredible conversation with Kitrena Young, a two-time cancer survivor whose story spans decades and highlights the unique challenges faced by adolescents and young adults (AYAs). We begin by learning about Kitrena's initial diagnosis of B-cell ALL with a Philadelphia chromosome at the age of eight, followed by a shocking relapse 23 years later. Her candor about how she recognized the early signs the second time around—bruising and fatigue—underscores the importance of self-awareness and advocacy.We discuss how navigating the adult healthcare system differed drastically from her pediatric experience. Kitrena takes us through her rapid efforts to get an urgent appointment and the emotional toll of being thrust back into the cancer world. With support from her brother and eventually finding care at the Memorial Sloan Kettering Cancer Center (MSKCC) through a compassionate voice on the phone, she exemplifies what it means to be proactive in your care journey.Fertility preservation is another focal point. Kitrena recounts her decision to freeze 15 eggs before starting treatment and how her perspective on parenthood has evolved. She walks us through the emotional and physical realities of exploring surrogacy and genetic testing post-transplant—particularly the complex issue of donor DNA requiring a skin biopsy for viable results.Kitrena doesn't shy away from discussing post-treatment life: weight gain linked to early menopause, a challenging international trip filled with setbacks and triumphs, and the frustrations of altered tastes and capabilities. Despite it all, she maintains a remarkable sense of humor and determination to continue traveling and living fully.Family and caregiver dynamics are woven throughout her story. She speaks lovingly about her partner's unwavering support and the strength of her younger brother, who stepped up when needed most. Her message to caregivers includes practical advice—especially around vigilance with medical billing, noting errors she encountered from appointments she never attended.Finally, Kitrena emphasizes the growing importance of therapy for both patients and caregivers. She encourages the AYA community to use available resources to work through trauma, grief, and uncertainty—pointing to virtual options that didn't exist in her earlier experience.Kitrena's journey is one of persistence, clarity, and empowerment. She brings vital, firsthand wisdom to the AYA cancer space, reminding us that while every survivor's path is different, no one should walk it alone.Thanks to our Season 17 Sponsors:Leukemia and Lymphoma Society (LLS): https://lls.org/and Incyte: https://incyte.com/FInancial Resource from the LINK: https://www.nbmtlink.org/financebookresources/ National Bone Marrow Transplant Link - (800) LINK-BMT, or (800) 546-5268.nbmtLINK Website: https://www.nbmtlink.org/nbmtLINK Facebook Page: https://www.facebook.com/nbmtLINKFollow the nbmtLINK on Instagram! https://www.instagram.com/nbmtlink/The nbmtLINK YouTube Page can be found by clicking here.To participate in the GVHD Mosaic, click here: https://amp.livemosaics.com/gvhd
In today's episode, supported by Shorla Oncology, we had the pleasure of speaking with Kate Gasparini, PharmD, BCOP, BCPPS, about the use of the oral formulation of imatinib (Imkeldi) for pediatric and adult patients with select leukemias and other malignancies. Gasparini is a pediatric oncology clinical pharmacy specialist at Memorial Sloan Kettering Cancer Center in New York, New York. In our exclusive interview, Gasparini discussed her role as a clinical pharmacy specialist in pediatric oncology, emphasizing her work in patient care, medication reviews, and supportive care. She also noted challenges in administering treatments to patients with dysphagia and emphasized the need for liquid formulations of common therapies. She explained the significance of the availability of the liquid formulation of imatinib, sharing its benefits for patients who struggle with swallowing. Gasparini also addressed potential barriers to accessing this medication, such as insurance coverage limitations, as well as the importance of considering the volume and palatability of liquid formulations to avoid adverse effects and ensure treatment adherence.
Celebrating Fathers and the Impact of FatherhoodIn this special Father's Day episode of the Truman Charities podcast, host Jamie Truman celebrates fathers, particularly her husband Jerry Truman, co-founder of Truman Charities. Jamie outlines how Truman Charities started with Jerry's initiative to raise funds for Leukemia research and has since grown, raising over $2 million. She discusses the significant impact fathers have within the family unit and the alarming statistics on youths without fathers. Jamie shares insights from her book 'Vanishing Fathers: The Ripple Effect on Tomorrow's Generation,' which explores the societal consequences of fatherlessness. Proceeds from the book support at-risk youth charities. The episode features discussions with notable individuals impacted by fatherlessness,00:00 Introduction and Father's Day Wishes00:26 The Origin of Truman Charities01:23 The Importance of Fathers04:10 Vanishing Fathers: The Book04:28 Notable Interviews and Stories06:34 Supporting At-Risk Youths06:54 Final Thoughts and Upcoming EventsConnect with Jamie at Truman Charities:FacebookInstagramLinkedInWebsiteYouTubeEmail: info@trumancharities.comThis episode was post produced by Podcast Boutique https://podcastboutique.com/
In today's episode, we spoke with Naval Daver, MD, about the evolving role of menin inhibition in acute myeloid leukemia (AML) and emerging data with revumenib (Revuforj) presented across ongoing clinical trials. Dr Daver is a professor in the Department of Leukemia and director of the Leukemia Research Alliance Program at The University of Texas MD Anderson Cancer Center in Houston, Texas.
In this week's episode, we' ll learn about how TET3 has a key role in GVHD. In mice, a deficiency of Tet3 in donor T cells inhibited pathogenic immunoglobulin class switching and suppressed lung fibrosis. Accordingly, TET3 may be a new therapeutic target in chronic GVHD. After that: rilzabrutinib, a BTK inhibitor for ITP. In a randomized, placebo-controlled trial, treatment produced rapid and durable platelet responses, with acceptable safety, in adults with immune thrombocytopenia who had failed multiple previous therapies. Finally: exploring pre-TCR surface expression patterns in T-cell ALL. Co-inhibition of the interleukin-7 receptor and pre-T cell receptor pathways may play a therapeutic role for a subset of T-lymphoblastic leukemias.Featured Articles: Deficiency of T follicular helper cell Tet3 DNA demethylation inhibits pathogenic IgG2c class switching and chronic GVHDSafety and efficacy of rilzabrutinib vs placebo in adults with immune thrombocytopenia: the phase 3 LUNA3 studySurface pTα expression predicts LCK activation and preclinical synergy of LCK and JAK coinhibition in adult T-ALL
Valerie David, also known as The Pink Hulk, is a three-time cancer survivor (non-Hodgkin's lymphoma, stage 2 breast cancer, and stage 4 metastatic breast cancer) who turned her journey of resilience into an award-winning one-woman show. Through humor, raw honesty, and advocacy, she inspires audiences worldwide—proving that even cancer won't stop her from taking center stage.Check out Valerie's show, The Pink Hulk here: https://pinkhulkplay.comKey Highlights:- Valerie trusted her inner voice when symptoms appeared, even when doctors initially dismissed them. If you are able to get second opinions, advocate for yourself, and listen to your gut, you'll find this to be useful in other parts of your own life.- Balancing intuition with fear over symptoms can be tricky, but Valerie advises: don't panic over nothing, don't choose to live in fear. Instead, stay proactive by communicating with your care team about any arising symptoms.About our guest:Valerie David is an actor, playwright, writer and editor. Her greatest accomplishment in life is being a three-time cancer survivor. She was diagnosed and treated for Stage III Non-Hodgkin's Lymphoma in 1999, Stage II Breast Cancer in 2014 and 2015, and Stage IV Breast Cancer in 2018. As of April 2019, she has beaten cancer again! Valerie reactivated her superhero within, and exactly 5 months after receiving hormone treatment only in pill form–no surgery, no radiation, no chemotherapy, Valerie no longer has active disease. She has since kept up a full schedule of performances–nothing has stopped her. Valerie's inspirational solo show, The Pink Hulk, has been accepted into almost 50 different play festivals worldwide since its 2016 debut, won multiple awards and has been touring since its very first performance, impacting audiences with the show's universal message of hope and empowerment. She has performed in over 25 different cities and globally, including in England, Sweden, Iceland, and Finland. A graduate of the American Academy of Dramatic Arts, her credits include the Off-Broadway production of A Stoop on Orchard Street, Cookie in Rumors and Claudia Shear's Blown Sideways Through Life. Films: How I Became that Jewish Guy, which premiered at a November 2015 NYC Film Festival, and Bridges and Tunnels. Valerie volunteers as a motivational speaker at the Leukemia & Lymphoma Society's Team in Training events and Make-A-Wish Foundation. As a marathon cyclist, she co-founded Cycle of Hope, which raises money for national and international cancer organizations through bike marathons. Her most recent biking event raised almost $5,000 for the American Cancer Society and the Leukemia & Lymphoma Society.Key Moments:At 7 minutes 28 seconds “What is my choice? Is my choice going to live in fear every single day? Is it going to be well, we'll deal with it when it happens. So I think what I've learned from cancer is don't worry until there's something to worry about.”Disclaimer: All content and information provided in connection with Manta Cares is solely intended for informational and educational purposes only. This content and information is not intended to be a substitute for medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.
In this special episode, Dr. Shaji Kumar from the Mayo Clinic speaks with Blood editor Dr. Laurie Sehn on a paper recently published in Blood, "Eliminating the Need for Sequential Confirmation of Response in Multiple Myeloma". The findings demonstrate eliminating the need for sequential confirmation of response in multiple myeloma. The study, involving 583 episodes of progression, found that simultaneous confirmation of disease progression using two different markers (e.g., serum protein electrophoresis and serum free light chain assay) was 98% accurate, compared to 82% for sequential confirmation. This suggests that simultaneous confirmation could improve clinical trial accuracy and reduce false censoring. The International Myeloma Working Group is set to revise its response criteria to incorporate these findings, potentially simplifying disease assessment and reducing the need for multiple blood draws.
To have your question featured in a future video, please email: questions@morses.tv Please include at least: Age, Weight and as much history as possible.
In this week's episode, we'll learn more about the identification and characterization of stem cell-like leukemia blasts using single cell multi-omics, cyclophosphamide as a treatment for non-immune effector cell-associated neurotoxicity in patients treated with B-cell maturation antigen, or BCMA, targeted CAR T-cell therapies, and how differences in glycosylation affect the clearance of human plasma-derived and recombinant von Willebrand factor concentrates.Featured Articles:Single-cell panleukemia signatures of HSPC-like blasts predict drug response and clinical outcomeCyclophosphamide mitigates non-ICANS neurotoxicities following ciltacabtagene autoleucel treatmentEnhanced α2-3–linked sialylation determines the extended half-life of CHO-rVWF
In this How I Treat Series episode Dr. Thomas Ortel leads a discussion with author Dr. Patrick Foy on his paper “How I diagnose and treat thrombocytopenia in geriatric patients”. See the full How I Treat series on geriatric hematology in volume 143 issue 3 of Blood Journal.
In this week's episode, we'll hear about new insights into PU.1-mutated agammaglobulinemia. Researchers show that haploinsufficiency of the master transcriptional regulator PU.1 causes agammaglobulinemia and dendritic cell deficiencies. These patients experience an array of infectious and non-infectious complications, but not leukemia. After that: venetoclax-based induction therapy in younger patients with AML. Venetoclax plus decitabine was associated with superior safety and non-inferior response rates compared to intensive chemotherapy. Is it time to consider lower-intensity therapy beyond older and unfit patients? Finally, a focus on venous thromboembolism. Researchers link BGAT, an enzyme pivotal to determining blood type, to risk of future VTE. They say high plasma levels of BGAT contribute to risk above and beyond what can be explained by von Willebrand factor and Factor VIII.Featured Articles:One hundred thirty-four germ line PU.1 variants and the agammaglobulinemic patients carrying themVenetoclax and decitabine vs intensive chemotherapy as induction for young patients with newly diagnosed AMLHisto–blood group ABO system transferase plasma levels and risk of future venous thromboembolism: the HUNT study
Livvy Bedard and Caeleigh Brown met while on the Swimming Team in Middle School. Caeleigh was diagnosed with Leukemia while a member of this team in January of 2017, shortly after setting her personal best during a swimming meet. Caleigh is now a Nursing Student at James Madison University. Livvy is working with the Leukemia and Lymphoma Society as she attempts to become a Visionary of the Year by raising money in honor of Caeleigh and what she went through. Livvy began this quest on March 27th and has an upcoming fundraising deadline of June 5th.
In this conversation, Jeff interviews MK Holmes, the campaign development manager for the Light the Night campaign with the Leukemia & Lymphoma Society (LLS). They discuss MK's background, her journey to LLS, and the impactful work the organization does in the community, particularly through events like Light the Night and the Pickleball for a Purpose tournament. MK shares insights into LLS's mission to cure blood cancers, the support they provide to patients, and how the community can get involved through fundraising and volunteering.Leukemia and Lymphoma SocietyCLICK HERE to donate to Jamie's Light the Night FundraiserCLICK HERE to register for Charlotte Light The Night 2025Special thanks to:The Carolina Factory & The Vannelle Family---------------------------------------------------------------------------------------The Best of LKNhttps://thebestoflkn.com/Hosted by:Jeff HammReal Estate BrokerCharlotte & Lake Norman (NC)https://lknreal.com/Support the show
In this episode of the Epigenetics Podcast, we talked with Ani Deshpande from Sanford Burnham Prebys about his work on epigenetic regulation and developing small molecules through high throughput screens for AML. Throughout our discussion, we delve into Dr. Despande's journey into the field of biology and science, tracing his evolution from a literature enthusiast in Mumbai to a dedicated cancer researcher. He reflects on his formative experiences during his PhD at Ludwig Maximilian University in Munich, where she developed murine models for refractory acute myeloid leukemia (AML). We examine these models' contributions to therapeutic discovery and understanding the intricate mechanisms underscoring AML's complexities. Transitioning to his postdoctoral work at Scott Armstrong's lab in Boston, Dr. Despande shares his insights on the importance of epigenetic regulators, such as DOT1L, in leukemias, and how they can serve as strategic therapeutic targets. His ambitious pursuit of translational research is further highlighted through his efforts in developing a conditional knockout mouse model and his collaborative work utilizing CRISPR technology to refine our understanding of epigenetic regulation in cancer pathogenesis. Moreover, we engage in a conversation about the challenges and opportunities that arise when establishing his lab at Sanford Burnham Prebys. Dr. Despande candidly discusses the delicate balance between pursuing topics of genuine interest versus adhering to grant fundability, underlining the tension researchers face in the current scientific landscape. His emphasis on the critical need for innovation within lab settings serves as a motivational call for emerging scientists to venture beyond the established templates that often inhibit groundbreaking discoveries. We conclude our dialogue with an exploration of his recent projects, which involve targeting specific epigenetic modifiers and how his lab's findings can contribute to greater understanding and potential treatments for not only AML but also other pediatric cancers driven by gene fusions. Dr. Despande's insights into the integration of modern technologies, such as CRISPR libraries, exemplify his commitment to pushing the boundaries of cancer research. In addition to discussing his scientific contributions, we touch upon Dr. Despande's foray into podcasting (The Discovery Dialogues), shedding light on his motivation to bridge the communication gap between scientists and the broader public. He articulates his desire to demystify scientific discoveries and promote awareness about the intricate journey of research that lays the groundwork for medical advancements. This multidimensional discussion not only highlights his scientific achievements but also emphasizes the importance of effective science communication in fostering public understanding and appreciation of research. References Deshpande AJ, Cusan M, Rawat VP, Reuter H, Krause A, Pott C, Quintanilla-Martinez L, Kakadia P, Kuchenbauer F, Ahmed F, Delabesse E, Hahn M, Lichter P, Kneba M, Hiddemann W, Macintyre E, Mecucci C, Ludwig WD, Humphries RK, Bohlander SK, Feuring-Buske M, Buske C. Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia. Cancer Cell. 2006 Nov;10(5):363-74. doi: 10.1016/j.ccr.2006.08.023. PMID: 17097559. Deshpande AJ, Deshpande A, Sinha AU, Chen L, Chang J, Cihan A, Fazio M, Chen CW, Zhu N, Koche R, Dzhekieva L, Ibáñez G, Dias S, Banka D, Krivtsov A, Luo M, Roeder RG, Bradner JE, Bernt KM, Armstrong SA. AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes. Cancer Cell. 2014 Dec 8;26(6):896-908. doi: 10.1016/j.ccell.2014.10.009. Epub 2014 Nov 20. PMID: 25464900; PMCID: PMC4291116. Sinha S, Barbosa K, Cheng K, Leiserson MDM, Jain P, Deshpande A, Wilson DM 3rd, Ryan BM, Luo J, Ronai ZA, Lee JS, Deshpande AJ, Ruppin E. A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing. Nat Commun. 2021 Nov 11;12(1):6512. doi: 10.1038/s41467-021-26788-6. Erratum in: Nat Commun. 2022 May 16;13(1):2828. doi: 10.1038/s41467-022-30475-5. PMID: 34764240; PMCID: PMC8586238. Related Episodes Targeting COMPASS to Cure Childhood Leukemia (Ali Shilatifard) The Menin-MLL Complex and Small Molecule Inhibitors (Yadira Soto-Feliciano) MLL Proteins in Mixed-Lineage Leukemia (Yali Dou) Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com
In this week's episode we'll learn about how frequent blood donation affects clonal hematopoiesis in older, male blood donors; the effect of immune microenvironment on response to bispecific antibodies in diffuse large B-cell lymphoma; and the feasibility of adding blinatumomab to early consolidation therapy in CD19-positive Ph-negative B-cell acute lymphoblastic lymphoma.Featured ArticlesClonal Hematopoiesis Landscape in Frequent Blood DonorsIntegrative genomic analysis of DLBCL identifies immune environments associated with bispecific antibody responseUpfront Blinatumomab Improves MRD Clearance and Outcome in Adult Ph-negative B-lineage ALL: The GIMEMA LAL2317 Phase 2 Study
In part two of the How I Treat Series on Transfusion Medicine Dr. Erica Wood interviews the "How I Manage Major Hemorrhage" author group: Drs. Jeannie Callium, Keyvan Karkouti, and Ron George.Find the full published review series in Volume 145 Issue 20 of Blood Journal.
A funeral homily for Mr. Peter Rebello at the church of St. Clement in Toronto on May 20, 2025. Peter died from Leukemia on May 13, the feast of our Lady of Fatima. He was 77.Music: Be not afraid by Bob Dufford with choir.org
Angela started her career as a critical care nurse in 2014. She received her first MSN in 2017 with an emphasis in public health. In 2022, she received her 2nd MSN in Adult/Gerontology Acute Care Nurse Practitioner. She and her husband have been practicing the Keto Diet since 2019 (which was right before COVID and one of their children being diagnosed with Leukemia); with all the stressors that they faced, the Keto Diet kept them healthy and happy through the worst. Disenchanted by modern medicine after learning about the keto diet and reluctant to make the transition as an NP, Angela found her way into Home Health as a Telehealth Primary and Palliative Care NP. Timestamps: 00:00 Trailer 01:25 Introduction 03:15 Nurse practitioner's independence benefits 09:14 ICU nutrition oversights during Covid 11:58 Keto diet and health struggles 14:19 Diet scams vs. genuine support 19:10 Orthopedic surgeon embraces metabolic health 22:33 Low carb lifestyle and nutrition 27:41 Rapid monitoring of hypertension patients 29:42 Revero's unique healthcare model 32:28 Balancing work and family time 34:58 Nutrition and nursing home residents 38:48 Improving elder care nutrition 42:18 Patients' surprising knowledge on keto/carnivore 45:10 Patient struggles in gaining weight 51:13 Creating a positive impact for patients 52:05 Where to find Skye Join Revero now to regain your health: https://revero.com/YT Revero.com is an online medical clinic for treating chronic diseases with this root-cause approach of nutrition therapy. You can get access to medical providers, personalized nutrition therapy, biomarker tracking, lab testing, ongoing clinical care, and daily coaching. You will also learn everything you need with educational videos, hundreds of recipes, and articles to make this easy for you. Join the Revero team (medical providers, etc): https://revero.com/jobs #Revero #ReveroHealth #shawnbaker #Carnivorediet #MeatHeals #AnimalBased #ZeroCarb #DietCoach #FatAdapted #Carnivore #sugarfree Disclaimer: The content on this channel is not medical advice. Please consult your healthcare provider.
Joao wants to know what happens when stem cells of our own, which have been cultivated outside the body, are reintroduced to the bloodstream. This got James Tytko thinking about autologous stem cell transplants, used as a treatment for some forms of blood cancer. He asked Tania Dexter, haematology registrar, and senior medical officer at the Anthony Nolan Institute, to help explain... Like this podcast? Please help us by supporting the Naked Scientists
In this heartfelt episode of the Surviving Siblings Podcast, host Maya Roffler welcomes Cryssy, a bereaved sibling who lost her younger sister, Danielle, to acute myeloid leukemia in 2012. As the oldest sibling, Cryssy took on the role of protector, caregiver, and advocate—navigating the heartbreak of watching her sister battle a devastating illness. Cryssy shares her deeply personal journey of anticipatory grief, the pain of losing Danielle at just 21 years old, and the complex emotions of grieving while trying to stay strong for her family. She opens up about the regret of not getting to say goodbye the way she wanted, the physical toll grief took on her body, and the creative, meaningful ways she keeps Danielle's memory alive every day. This episode is a powerful conversation about sibling loss, anticipatory grief, and finding purpose after tragedy. Cryssy also shares how honoring her sister through traditions, a beloved stuffed animal, and small daily acts has helped her heal—and how grief can manifest physically in ways we might never expect. If you've ever felt the weight of grieving a sibling while being the “strong one” for others, Cryssy's story will remind you that love endures, even through the pain. In This Episode: (00:01:00) – Danielle: A Birthday Gift Sister Cryssy shares how Danielle was born just two days before her own birthday, how they celebrated together, and how their sibling bond was filled with love, chaos, and laughter. (00:04:00) – Big Sister, Protector, Mama Bear Growing up as the oldest, Cryssy stepped into a protective role, helping raise Danielle and their brother, shielding them, and taking on family responsibilities from a young age. (00:05:00) – The Call That Changed Everything Cryssy recounts the moment she learned Danielle was being rushed to the hospital after a bloody nose turned into a leukemia diagnosis—and how she instantly began grieving. (00:08:00) – Facing Acute Myeloid Leukemia Cryssy explains Danielle's diagnosis, the aggressive treatment process, and how she tried to stay hopeful on the outside while preparing herself internally for the worst. (00:11:00) – Holidays in the Hospital Danielle asked Cryssy to decorate her hospital room for Halloween and Christmas—keeping their family traditions alive despite spending their favorite holidays in a hospital room. (00:14:00) – The Final Christmas Together Cryssy reflects on their last Christmas, staying up all night talking, exchanging meaningful gifts, and creating treasured memories in what would be Danielle's final holiday. (00:19:00) – Saying Goodbye Without Words Cryssy shares the experience of Danielle's “surge” before passing, the bittersweet final days, and the deep regret of not being able to say goodbye the way she had hoped. (00:24:00) – Preparing Danielle's Goodbye Honoring her sister's love of style, Cryssy lovingly prepared Danielle for her viewing—painting her nails, doing her hair, dressing her in jewelry, and ensuring she looked radiant. (00:31:00) – A Dream Visit From Danielle Months after Danielle's passing, Cryssy had a vivid dream of Danielle smiling and telling her, “It's okay to be okay”—a powerful, healing moment that brought her comfort. (00:37:00) – Grief's Physical Impact Cryssy opens up about how her grief manifested in physical illness, leading to hospitalization, sepsis, and a near-death experience that she believes Danielle helped her survive. (00:48:00) – Finding Purpose in Grief Cryssy reflects on how grief has shaped her purpose, giving her strength to help others and reminding her that grief is love in a different form. This episode is sponsored by The Surviving Siblings Connect with Cryssy: Tik Tok: https://www.tiktok.com/@cryssycryssycryssy Email: Crystalmperry@yahoo.com Instagram: https://www.instagram.com/Nimbeedonut Facebook: https://www.facebook.com/CryssyPerry/ Connect with Maya: Podcast Instagram: https://www.instagram.com/survivingsiblingspodcast/ Maya's Instagram: https://www.instagram.com/mayaroffler/ TikTok: https://www.tiktok.com/@survivingsiblingspodcast Twitter: https://x.com/survivingsibpod Website: thesurvivingsiblings.com Facebook Group: The Surviving Siblings Podcast YouTube: The Surviving Siblings Podcast Patreon: https://www.patreon.com/TheSurvivingSiblingsPodcast
Imagine the shock and horror of having a child be diagnosed with Acute Myeloid Leukemia, going through treatment for that for 8 months,, relapsing 2 months later, and then being told that the first diagnosis was wrong, and that the child actually had Ewings Sarcoma. That is what happened to then 2 1/2 year old Connor Mocey who is now 5 years old and doing as well as possible while dealing with this difficult Bone Cancer.
Enjoy a replay of Monday night's Patriots post-draft party co-hosted by Andrew and the Boston Herald's Doug Kyed. Together, they interview ESPN's Mina Kimes, Jason McCourty, Danny Kelly, Danny Heifetz, Phil Perry, Mike Giardi, Taylor Kyles, Michael Hurley, Sam Monson and Steve Palazzolo all about the Patriots draft and potential for next season. Donate at https://princesshallieforever.com — all proceeds go to Doug Kyed's Leukemia and Lymphoma fundraiser in honor of his daughter, Hallie. Pats Interference is presented by: Gametime! Take the guesswork out of buying NFL tickets with Gametime. Download the Gametime app, create an account, and use code CLNS for $20 off your first purchase. Download Gametime today. What time is it? Gametime! Terms apply. Go to https://gametime.co ! Learn more about your ad choices. Visit megaphone.fm/adchoices