Disease of anatomical entity that is located in the central nervous system or located in the peripheral nervous system
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Dr. Hoffman continues his conversation with Dr. Garth Nicolson, Founder, President, Chief Scientific Officer, and Emeritus Research Professor of Molecular Pathology at the Institute for Molecular Medicine in Huntington Beach, California, and Research Advisor for Nutritional Therapeutics, makers of NTFactor.
Unlocking the Power of Mitochondria: Dr. Garth Nicolson, a leading expert in molecular pathology, explores the critical role of mitochondria in energy production and overall health. His groundbreaking research reveals how repairing and restoring cell membranes improves health by increasing energy, decreasing fatigue, and slowing the aging process. The discussion delves into Dr. Nicolson's findings, including his influential fluid mosaic model of cell membrane structure. The focus then shifts to the importance of maintaining mitochondrial membrane integrity to combat aging and various age-related clinical conditions. Dr. Nicolson explains the benefits of membrane lipid replacement therapy using NT Factor Lipids to restore mitochondrial function, address fatigue, support recovery from chemotherapy, aid in chronic illnesses like fibromyalgia and long COVID, and assist in conditions such as schizophrenia, autism, and EMF sensitivity. The episode highlights the broad therapeutic potential of NT Factor Lipids, emphasizing their role in enhancing energy levels, promoting healing, and improving overall cellular health.
This podcast is brought to you by Outcomes Rocket, your exclusive healthcare marketing agency. Learn how to accelerate your growth by going to outcomesrocket.com AI is revolutionizing healthcare by offering new ways to solve complex problems, emphasizing data-driven solutions over traditional hypothesis-based approaches. In this episode, Dr. Sam Perli, Chief Scientific Officer and founding member of Thinkhat, discusses how his company is building an AI-powered venture studio to launch innovative healthcare and life sciences companies. Thinkhat serves physicians with its Noki co-pilot for automated tasks, patients with noninvasive monitoring solutions, and pharmaceutical companies with its Encode AI engine for optimizing sequence medicines. Dr. Perli acknowledges skepticism around AI but highlights its potential to solve complex problems like protein folding and neurodegenerative diseases. He encourages openness to AI and suggests cost-effective development strategies, including tapping into global talent pools and leveraging resources in places like Puerto Rico. Tune in and learn how Thinkhat leverages AI to address previously unsolvable problems in medicine, providing a diverse set of solutions across the healthcare industry! Resources: Connect and follow Dr. Sam Perli on LinkedIn. Learn more about Thinkhat on their LinkedIn and website. Email Thinkhat directly here. Email Sam here. Fast Track Your Business Growth: Outcomes Rocket is a full-service marketing agency focused on helping healthcare organizations like yours maximize your impact and accelerate growth. Learn more at outcomesrocket.com
Parkinson's Disease has long been a clinical diagnosis. But recently, there have been proposals to redefine the disease based on biomarkers of alpha-synucleinopathy and dopaminergic dysfunction. A similar shift has already occurred in Alzheimer disease, with the “amyloid, tau, and neurodegeneration,” or ATN, classification system. Our guest today, Michael Okun, is is Professor of Neurology and Director of the Norman Fixel Institute for Neurological Diseases at the University of Florida and medical advisor for the Parkinson's Foundation. He co-authored an op-ed in JAMA last summer in JAMA arguing that there would be benefits to a biological definition of Parkinson's - but there would also be risks. He'll unpack both sides of this debate today with Dr. Christine Doss Esper, Associate Professor of Neurology at Emory University. Series 6, Episode 5 Featuring: Guest: Dr. Michael Okun, is Professor of Neurology and Director of the Norman Fixel Institute for Neurological Diseases at the University of Florida and medical advisor for the Parkinson's Foundation Interviewer: Dr. Christine Doss Esper, Associate Professor of Neurology at Emory University Disclosures: None
Percheron Therapeutics Ltd has submitted a non-binding proposal to an international pharmaceutical company to in-license a new drug development program for a rare neurological disease. The program is described as ‘clinic ready' and prepared for human trials. Negotiations for a definitive agreement are expected to take 8-12 weeks, with plans to begin human clinical trials in early 2026, subject to a successful investigational new drug (IND) application with the US Food and Drug Administration (FDA). Percheron stated that investor interest in the company's next steps remained high. CEO Dr James Garner noted that extensive due diligence had been conducted across a broad range of programs, leading to discussions on business terms with the preferred candidate. The company believes this represents a strong opportunity for shareholders. Alongside preparing its IND submission, Percheron will continue assessing alternative clinical opportunities as a contingency measure and for potential future expansion. The company intends to provide updates as discussions progress. #PercheronTherapeutics #DrugDevelopment #RareDiseases #NeurologicalDisorders #ClinicalTrials #Biopharma #Pharmaceuticals #FDAApproval #INDApplication #MedicalResearch #BiotechInvestment
This week on The Genetics Podcast, we're joined by Hilary Martin, Group Leader in Human Genetics at the world-renowned Wellcome Sanger Institute. Hilary and Patrick discuss her group's work on neurodevelopmental conditions, the role of common genetic variants in rare disease, and how to untangle the impact of direct and indirect genetic influences on various traits. Find out more Nature paper: Examining the role of common variants in rare neurodevelopmental conditions https://www.nature.com/articles/s41586-024-08217-y Genes and Health Project https://www.genesandhealth.org
Você sabe o que é uma Taenia e como ela afeta a saúde? Separe trinta minutinhos do seu dia e descubra, com a Mila Massuda, como esses parasitas se disseminam, quais riscos eles oferecem, as doenças relacionadas (teníase e cisticercose) e a importância de práticas adequadas de higiene e alimentação para a prevenção de infecções.
Henry O'Connell is the CEO and Co-Founder of Canary Speech, which analyzes voice biomarkers to detect various medical conditions, including neurological disorders like Alzheimer's, Parkinson's, and cognitive decline. Their approach looks at the underlying mechanisms of speech controlled by the central nervous system rather than the words spoken. The technology has been validated to correlate with clinical diagnoses at a high accuracy level. It provides real-time, objective assessments to healthcare providers, which could help overcome biases and reveal early signs of the presence of a disease. Henry explains, "Canary Speech is now about eight years old. Jeff Adams, my business partner and friend, and I created Canary Speech to evaluate voice for a range of different human conditions and diseases. We actually established an approach that was unique in the market. Jeff has a history of innovation in voice and voice analysis. He was the lead that developed the first natural language processing commercial tools. He also led the team that developed Dragon naturally speaking, the most prominent tool for transcription services in healthcare. He also led the team that built the Amazon Echo." "With that deep experience and 40 years of relationship together and friendship, we created Canary speech. Canary looks at sub-language characters and elements. We look at 15 million different data elements every minute, and we process those for a range of different diseases, progressive neurological diseases, cognitive health, and behavioral health. We're beginning to build models for children's health." "Everything that we have built has been built in clinical settings with peer review with organizations such as The Harvard Beth Israel, Hackensack Meridian, Intermountain Healthcare, Cala Hospital in Dublin, Ireland, Belfast Hospital, and Alster Hospital in Belfast, and also National Institutes of Health in Japan. So, we use those rigorous environments and those clinical settings to build local biomarker algorithms that can identify." #CanarySpeech #Biomarkers #NeurodegenerativeDiseases #Alzheimers #Parkinsons #CognitiveDecline canaryspeech.com Download the transcript here
Henry O'Connell is the CEO and Co-Founder of Canary Speech, which analyzes voice biomarkers to detect various medical conditions, including neurological disorders like Alzheimer's, Parkinson's, and cognitive decline. Their approach looks at the underlying mechanisms of speech controlled by the central nervous system rather than the words spoken. The technology has been validated to correlate with clinical diagnoses at a high accuracy level. It provides real-time, objective assessments to healthcare providers, which could help overcome biases and reveal early signs of the presence of a disease. Henry explains, "Canary Speech is now about eight years old. Jeff Adams, my business partner and friend, and I created Canary Speech to evaluate voice for a range of different human conditions and diseases. We actually established an approach that was unique in the market. Jeff has a history of innovation in voice and voice analysis. He was the lead that developed the first natural language processing commercial tools. He also led the team that developed Dragon naturally speaking, the most prominent tool for transcription services in healthcare. He also led the team that built the Amazon Echo." "With that deep experience and 40 years of relationship together and friendship, we created Canary speech. Canary looks at sub-language characters and elements. We look at 15 million different data elements every minute, and we process those for a range of different diseases, progressive neurological diseases, cognitive health, and behavioral health. We're beginning to build models for children's health." "Everything that we have built has been built in clinical settings with peer review with organizations such as The Harvard Beth Israel, Hackensack Meridian, Intermountain Healthcare, Cala Hospital in Dublin, Ireland, Belfast Hospital, and Alster Hospital in Belfast, and also National Institutes of Health in Japan. So, we use those rigorous environments and those clinical settings to build local biomarker algorithms that can identify." #CanarySpeech #Biomarkers #NeurodegenerativeDiseases #Alzheimers #Parkinsons #CognitiveDecline canaryspeech.com Listen to the podcast here
In this episode of Life Science Success, my guest is John McDonough, the Executive Chairman and CEO of Sunbird Bio. John is a seasoned life sciences executive with over 30 years of experience, known for his impressive track record of raising capital and creating substantial market value. He currently leads Sunbird Bio, a company at the forefront of developing innovative blood-based diagnostic tests for neurological disorders, particularly Alzheimer's disease. John's expertise extends beyond Sunbird Bio, as he also serves as chairman at Cytrellis Biosystems and BioPorto Diagnostics, and is the founder and president of the Crush Colon Cancer Foundation. With a history of successful IPOs, acquisitions, and mergers, John brings a wealth of knowledge and experience to our conversation about the future of neurological diagnostics and the life sciences industry. 00:00 Introduction to Life Science Success Podcast 01:20 Interview with John McDonough Begins 01:44 John McDonough's Career Journey 03:33 Challenges and Opportunities in Diagnostics 05:24 Significant Changes in Life Sciences 08:10 Sunbird Bio's Vision and Innovations 10:27 Development and Impact of Blood-Based Diagnostics 12:23 Future of Diagnostics and Neurological Disease 27:01 Philanthropy and Leadership Insights 28:36 Securing Funding and Company Growth 35:40 Leadership Advice and Personal Inspirations 42:31 Conclusion and Final Thoughts
Harnessing Yoga's Potential in Neuro Rehabilitation and the Gut-Brain Connection: Nutritionist Leyla Muedin discusses a pilot study from Germany highlighting the benefits of integrating yoga into inpatient neuro rehabilitation for conditions like multiple sclerosis and stroke. The study shows significant improvements in pain, spasticity, anxiety, and overall quality of life. Additionally, Leyla explores the expanding research on the gut-brain axis, revealing how a healthy gut microbiome influences mental resilience and stress response. She emphasizes the importance of addressing both physiological and psychological factors to manage anxiety and improve mental health.
Guest Michael Greicius is an authority on Alzheimer's disease. He makes the case that while effective treatments have remained elusive, there are high hopes for new approaches that target tau proteins in the brain associated with the disease. In the meantime, to reduce Alzheimer's risk stay active, eat well, and manage circulatory risks, but skip genetic testing for now until better treatments emerge, Greicius tells host Russ Altman on this episode of Stanford Engineering's The Future of Everything podcast.Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your quest. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: Michael GreiciusConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces guest Michael Greicius, a professor of neurology and neurological sciences at Stanford University.(00:02:12) Understanding Alzheimer's DiseaseThe roles of amyloid and tau proteins in Alzheimer's disease.(00:04:53) Challenges in Developing TreatmentsThe multiple hurdles in creating Alzheimer's therapies.(00:09:07) Current Alzheimer's DrugsThe controversies and limitations of recently approved drugs.(00:10:23) Amyloid Plaques and Their ImpactWhy removing amyloid plaques hasn't improved patient outcomes.(00:14:29) Problems with Alzheimer's TrialsThe disconnect between amyloid removal and patient outcomes.(00:18:03) Functional Unblinding and Trial BiasHow functional unblinding affects trial results and drug evaluations.(00:23:51) The Potential of Targeting TauNew breakthroughs in targeting tau protein for Alzheimer's.(00:26:35) The Future of PreventionPotential preemptive treatments for Alzheimer's and their administration.(00:29:19) Lifestyle and Risk ReductionRecommendations for reducing risk of Alzheimer's disease.(00:31:43) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook
On December 13, 2024 we spoke with the speakers at our annual UTSA Neuroscience Symposium, on the Basal Ganglia Circuitry. Topics of discussion included the heterogeneity of cells and connections, the usefulness of the idea of cell types (or lack thereof), and the relationship between neuromodulators and fast synaptic transmission. Sorry about the sound quality on this one. Guests: Charles Gerfen, Senior Investigator, National Institute of Mental Health Joshua Goldberg, Associate Professor, Department of Medical Neurobiology, The Hebrew University Zayd Khaliq, Senior Investigator, National Institute of Neurological Diseases and Stroke Tianyi Mao, Senior Scientist, Vollum Institute, Oregon Health & Science University Gilad Silberberg, Professor | Docent, Department of Neuroscience, Karolinska Institute D. James Surmeier, Professor, Department of Physiology, Feinberg School of Medicine, Northwestern University Host: Charles Wilson, Department of Neuroscience, Developmental and Regenerative Biology, UTSA
Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma and Biotech world.The FDA's accelerated approval pathway, established in 1992, has allowed over 200 new drugs to come to market based on surrogate endpoints. While many products have later received full FDA approval, recent withdrawals like Pfizer's Oxbryta and Takeda's Exkivity have raised concerns about the risks of this pathway. Despite some high-profile failures, the program has a strong track record, with over half of accelerated approvals converting to full approval. The pathway has been used primarily for cancer treatments but is now expanding to other disease areas like neurological and rare diseases. Recent failures of confirmatory trials for drugs like Sarepta's Elevidys have prompted experts to call for tighter timelines and better biomarkers for surrogate endpoints in order to improve the program. The future of the accelerated approval pathway is under scrutiny, with questions arising about how often it should be used and what areas it should focus on next.AbbVie's Tavapadon showed improvement in motor and daily living complications in a Phase III trial, following the failure of another key cerevel asset, Emraclidine. Relmada Therapeutics is considering strategic alternatives, including a potential sale, after halting two Phase III trials for a major depressive disorder drug. Other news includes BioAge discontinuing a Phase II obesity study, Merck's promising anti-ROR1 ADC data for lymphoma treatment, and Novo and Catalent's $16.5 billion deal receiving EU approval. Additionally, Vertex and Beam report advances in SCD cell and gene therapies, while evidence grows for the potential of GLP-1s in Alzheimer's disease.Recent studies have shown that GLP-1 receptor agonists, commonly used for weight loss and diabetes, may have potential in treating Alzheimer's disease. Phase III results from Novo Nordisk are expected next year. Additionally, amylin analogs are emerging as a potential alternative or complement to GLP-1 receptor agonists for weight loss with a cleaner tolerability profile. Other news includes a weight loss victory claimed by Lilly over Novo in a head-to-head study, FDA action alerts, and promising cancer therapies from companies like AstraZeneca and Merus. The FDA is also investigating the safety of Bluebird's gene therapy Skysona for hematologic malignancies. Applied Therapeutics recently faced a crash after FDA rejection of a rare disease drug. Overall, the potential of GLP-1s in Alzheimer's disease and the emergence of amylin analogs in weight loss are significant developments in the biopharma industry.
Mike interviews Dr. Michael Okun on Parkinson's Disease. Michael Okun, MD, is a board-certified neurologist, movement disorders specialist, neuroscientist, and author who practices with the philosophy that ‘the patient is the sun' and should be at the center of all care decisions. He co-founded and co-directs the internationally renowned Norman Fixel Institute for Neurological Diseases with neurosurgeon partner and friend Kelly Foote, MD. Since 2006, he has served as both the Medical Director and, most recently, the Medical Advisor for the Parkinson's Foundation. Michael Okun Book: https://amzn.to/3Vj5GHW Website: https://neurology.ufl.edu/profile/okun-michael/ --- Support this podcast: https://podcasters.spotify.com/pod/show/bobandbrad/support
Octopus camouflage is incredibly hard workOctopuses have the remarkable ability to change their appearance in the blink of an eye – assuming new skin coloration and patterns for camouflage or communication. A new study in the journal PNAS has explored how much energy this takes, and it turns out transforming themselves is a workout harder than you'd ever get at the gym. Dr. Kirt Onthank is a professor of Biology at Walla Walla University and known as The Octopus Guy on social media.Bigger isn't better when it comes to dog brainsDog bodies and brain sizes vary enormously, but a new study comparing dogs' cognitive abilities and personalities with brain size reveals some surprises. The research, led by evolutionary biologist Ana Balcarcel, found that the biggest brains relative to their body sizes belong to the small, anxious, excitable companion dogs, while the trainable, obedient working breeds are not gifted when it comes to volume of brain tissue. The work was published in the journal Biology Letters.This universe is too sparse, this one's too dense, and this one? Well, it'll doOur universe might seem like it's perfectly tuned for life, but when it comes to the role dark energy plays in the emergence of life, it turns out that our universe might not be so special after all. A new study that simulated the development of hypothetical universes with different amounts of dark energy suggests the optimal amount of dark energy to enable the evolution of life is only one-tenth of the density in our universe. Daniele Sorini, a postdoctoral researcher at Durham University and his team published their work in Monthly Notices of the Royal Astronomical Society. Why a smack on the lips might have come from a snack on a tickLip mashing is an oddity in the animal kingdom. Other than humans, few species have adopted the custom of pressing lips together as a signal of affection. A new theory for why humans kiss suggests it emerged from primate grooming practices, and the lip-lock has its roots in us slurping up parasites we've combed from a companion's fur. Dr. Adriano Lameira, an evolutionary psychologist at the University of Warwick published his new hypothesis in the journal Evolutionary Anthropology. Taking out our brains' trash may be key to maintaining a healthy brainSome scientists think it's possible that a host of neurological disorders, from Alzheimer's to Parkinson's, could be connected to problems with the way the brain rids itself of metabolic waste. A couple of recent studies in Nature are helping this longstanding puzzle about how this waste removal system works and what we might be able to do about it when it doesn't. A study published in Nature describes how synchronized electrical waves help flush the waste out when we sleep. Jonathan Kipnis, a neuroimmunologist from Washington University in St. Louis, said our neurons that are driving this waste removal system through what's known as the glymphatic system. A separate study of how gamma frequency stimulation, at 40 cycles per second, can kickstart gamma waves that are compromised in the brains of people with Alzheimer's. Li-Huei Tsai, a neuroscientist from MIT, said they found this stimulation flushes out beta-amyloid peptides in the brains of mice that would otherwise build up and form plaques which are the hallmark of diseased Alzheimer's brains.
Kamila has been through a lot. Not the least of which has been living in a very sensitive body since birth. A gifted athlete and loving sister, Kamila's life was rocked when the pandemic halted her professional beach volleyball career and then her beloved teenage brother was diagnosed with cancer. Looking back, Kamila has had TMS for her whole life (like so many of us), but it really ramped up with the grief she was experiencing and the pressures of pro sports. We discuss it all here today! This lovely and wise girl offers so many gold nuggets of guidance and empathy - it's a conversation that will really help to evolve your healing. Join us! For a limited time, we are building our LAUNCH TEAM for MIND YOUR BODY! The first 50 people to sign up will receive an advance copy of the book RIGHT NOW and be in our inner circle, working to carry this message. Click here to join us! JOIN THE LAUNCH TEAM Don't forget to PRE-ORDER MIND YOUR BODY! I AM SO FREAKING EXCITED FOR YOU TO GET YOUR HANDS ON THIS BOOK AND HAVE ACCESS TO THE GUIDANCE THAT HAS BEEN BUILDING IN MY MIND FOR 20 YEARS! Please pre-order now to help me get the word out to people all over the world. Each pre-order raises the algorithm and allows me more power and choice in sharing this life-changing information. I appreciate you! PRE-ORDER MIND YOUR BODY AND HELP ME SPREAD THIS MESSAGE ALL OVER THE WORLD!!! https://www.yourbreakawake.com/book FREE GIFTS AVAILABLE FOR PRE-ORDERS ONLY Get a copy for yourself. By pre-ordering just one copy of MIND YOUR BODY, you'll receive a free ticket to the first of its kind, virtual MIND YOUR BODY CON in late February (after you've had a little time to enjoy and take in the book).This event will immerse you in the teachings of MindBody medicine and connect you with fellow humans committed to choosing freedom over pain. It's a virtual book club with me! Be a part of the movement! When you pre-order three or more copies of MIND YOUR BODY, you'll secure your spot at an exclusive, intimate VIRTUAL afternoon with me.. This is your chance for us to connect and dive deeply into the transformative practices from the book with a select group of notable special guests who are passionate about spreading the MIND YOUR BODY message. Share this life-changing knowledge with friends and family, and help start a revolution in how we see and mind our bodies. Go to: www.nicolesachs.com and you'll see the all the instructions to receive your free gifts. COME TO OMEGA JUNE 22-27, 2025! CLICK HERE. Come play with us on our new site! www.yourbreakawake.com Click the link and then click around within. There are so many free resources (including a new free video on all things TMS on the home page) that can get you on your way. And, of course, if you're ready for some hand-holding and extra support on your journey, click on the EDUCATION tab for all of our courses and offerings, or join our MEMBERSHIP community. If you are a practitioner looking to specialize in this work or bring it to your community, get the first module of the Sarno x Sachs Solution for free! Click here: www.sarnosachs.com Life can be richer, fuller, better - and much less painful. We can't wait to see what you can do. Producer: Lisa Eisenpresser ALL MY RESOURCES:Instagram: Follow me on insta @nicolesachslcsw for tons of new contentWebsite: www.yourbreakawake.comYouTube: The Cure for Chronic Pain with Nicole Sachs, LCSWBook: The Meaning of TruthFB Closed Group:JournalSpeak with Nicole Sachs, LCSWOMEGA General info: OMEGA INSTITUTESubscribe Apple Podcasts Deezer iHeart RadioPublic RSS Spotify
Early diagnosis and treatment of Parkinson's disease is critical to slowing its progression. Long before neurological symptoms appear, patients exhibit early signs, some of which are associated with specific chemical scent signatures known as volatile organic compounds. Researchers study these as early biomarkers of disease for future diagnostics applications. In this episode, Iris Kulbatski from The Scientist spoke with Drupad Trivedi, a University of Manchester biomedical researcher and lecturer in analytical and measurement science, to learn more about how fatty skin secretions in Parkinson's disease and one woman's sensitive nose may lead to early detection and intervention. The Scientist Speaks is a podcast produced by The Scientist's Creative Services Team. Our podcast is by scientists and for scientists. Once a month, we bring you the stories behind news-worthy molecular biology research.
In this captivating and thoroughly engaging episode of Join the Docs, our dynamic duo, Professor Jonathan Sackier and Doctor Nigel Guest, embark on an enlightening and comprehensive journey into the intricate labyrinth of the human brain and nervous system. They unravel the tangled web of neurological diseases, with a special spotlight on multiple sclerosis (MS). This isn't just a superficial overview; The Docs delve deep into the brain's complex structure, its multifaceted functions, and the critical importance of the nervous system's intricate wiring. Imagine it as a high-stakes game of Operation, but with fewer buzzers and a lot more brain power. The Docs also explore the fascinating realms of cranial nerves and proprioception, which might sound like a fancy term for knowing where your nose is without looking, but it's so much more. With The Docs guiding the way, you'll get an inside look into why your body ‘nose' what it's doing - even when you don't!Who better to shed light on the rollercoaster ride of living with MS than Montel Williams? He rolls in to share his deeply personal journey, complete with all the twists, turns, and loop-de-loops that come with it. The Docs dive into his initial symptoms, which were more confusing than a plot twist in a soap opera, and the myriad challenges he faced in getting a diagnosis. Montel's story is not just about the physical and emotional struggles but also about the resilience and determination required to navigate life with MS. He also passionately advocates for cannabis as a treatment for neuropathic pain, making a compelling case that might just leave you reefer-ing to it in a new light.What's the takeaway from this brainy banter? The conversation underscores the paramount importance of awareness, early diagnosis, and resilience in managing neurological conditions. It's a powerful reminder that when it comes to your health, the best approach is to always have the heads up.So, tune in, get your neurons firing, and remember: knowledge is brain power! This episode of Join the Docs is not just an educational experience but also an inspiring call to action for anyone dealing with neurological conditions or simply interested in the wonders of the human brain. So, give your brain a stem cell-bration!!—--DISCLAIMER: The views and opinions expressed on Join the Docs are those of Dr. Nigel Guest, Jonathan Sackier and other people on our show. Be aware that Join the Docs is not intended to be medical advice, it is for information and entertainment purposes only - please, always take any health concerns to your doctor or other healthcare provider. We respect the privacy of patients and never identify individuals unless they have consented. We may change details, dates, place names and so on to protect privacy. Listening to Join the Docs, interacting on our social media, emailing or writing to us does not establish a doctor patient relationship.To Contact Us: For a deeper dive on this episode's issue, merchandise and exclusive content, head to www.jointhedocs.comFollow us on youtube.com/JoinTheDocs Follow us on instgram.com/JoinTheDocsFollow us on tiktok.com/JoinTheDocsFollow us on: facebok.com/JoinTheDocsFollow us on: x.com/JoinTheDocs
Many forms of neurological diseases have been deemed hopeless for treatment and cure. Many watch as their loved ones disappear. Science in the US is behind the times and we actually know more about prevention and treatment than ever before. If you or your loved one suffers or you fear being at risk for Alzheimer's, Dementia, ALS, Parkinson's or history of TBI… this show is for you. LaValleperformancehealth.comSee omnystudio.com/listener for privacy information.
Parkinson's disease (PD) is a “clinical” diagnosis, based on a person's medical history, symptoms, and physical exam. Although certain laboratory or imaging tests can be helpful in reaching a diagnosis, no single test can confirm PD. Among the tests currently used to support a PD diagnosis, or to rule out other conditions that can mimic PD, are magnetic resonance imaging (MRI) of the brain, the dopamine transporter scan (DaTscan) to look at how dopamine is transported in certain areas of the brain, Syn-One, or skin biopsies, and blood work. Sometimes, a PD diagnosis is straightforward based on the presence of certain symptoms, but in other cases, it may take a number of clinic visits to make a definitive diagnosis. The best way to ensure a correct diagnosis of PD, or a similar condition, is to see a neurologist specializing in movement disorders. One of the leading Parkinson's specialists is Dr. Michael Okun, National Medical Advisor for the Parkinson's Foundation and Director of the Fixel Institute for Neurological Diseases at the University of Florida in Gainesville. In this podcast episode, he explains some of the current tools for making a Parkinson's diagnosis, how they are used, and some of their limitations.
In this compelling episode of Research Renaissance, host Deborah Westphal sits down with Afreen Allam, the CEO and founder of SiNON Nano Sciences and a 2023 Termeer Fellow. Afreen shares her journey from aspiring medical student to biotech entrepreneur, discussing her groundbreaking work in drug delivery for neurological diseases. The conversation delves into the challenges and triumphs of developing a platform that can cross the blood-brain barrier, offering hope for the treatment of diseases like Cancer, Alzheimer's, Parkinson's, and brain tumors.Key Discussion Points:SiNON Nano Sciences' Mission: Afreen explains the innovative approach her company takes to target drug delivery across the blood-brain barrier, using a carbon-based nanoparticle that can safely and effectively transport medications to the brain.Personal Journey: Afreen reflects on her transition from a pre-medical student to a biotech entrepreneur, sharing how her experiences volunteering at the Duke Cancer Center inspired her to pursue research that could improve the quality of life for patients.Challenges in Drug Delivery: The discussion covers the unique difficulties of delivering drugs to the brain, the limitations of current technologies, and how SiNON Nano Sciences aims to overcome these obstacles with their platform.The Importance of Support and Mentorship: Afreen highlights the significance of mentorship and support systems, particularly her experience as a 2023 Termeer Fellow, which provided her with valuable resources, connections, and guidance.The Future of Drug Delivery: Afreen discusses the potential partnerships with pharmaceutical companies and the importance of collaboration in advancing treatments for neurological diseases.Guest Bio: Afreen Allam is the CEO and founder of SiNON Nano Sciences, a biotech startup focused on developing a platform for targeted drug delivery to the brain. A 2023 Termeer Fellow, Afreen is passionate about improving patient outcomes and has a background in biochemistry, microbiology, and business.Call to Action: Subscribe to Research Renaissance for more episodes featuring trailblazers in brain science and healthcare innovation. Visit tofflertrust.org for additional resources and updates. Until then, onward and upward!To learn more about the breakthroughs discussed in this episode and to support ongoing research, visit our website at tofflertrust.org. Technical Podcast Support by Jon Keur at Wayfare Recording Co.
Maya Ghazal joins us live from the UK, in between her flying trainings, and shares her background from fleeing war-torn Syria to becoming a licenced pilot in the UKAlex of House of Social has the tips you need for your business to thriveWe get the latest in the fight against Alzheimer's disease from Dr Derk Krieger, Consultant of Neurology at Fakeeh University Hospital Discussing online market places with Your Bazaar's Robbie KennedyAnd would you track your partner? Clinical Psychologist Dr Thoraiya Kanafani tells us what it means if you do or you don't.See omnystudio.com/listener for privacy information.
Information Morning Moncton from CBC Radio New Brunswick (Highlights)
Melissa Nicholson's mother, Bev Crossman, died this week following years of progressive neurological symptoms.
In this episode of the Brain & Life podcast, co-host Dr. Katy Peters is joined by Helen Kearney, a dressage rider from Ireland who competed in the 2021 Paralympics. Helen shares about her Friedreich's Ataxia diagnosis, how she connects with her horse, and her Paralympic experience. Dr. Peters is then joined by Dr. Sub Subramony, a board-certified neurologist and neuromuscular medicine specialist at the Norman Fixel Institute for Neurological Diseases at University of Florida. Dr. Subramony explains what Friedreich's Ataxia is, how it is diagnosed and treated, and what the future looks like for patients and their families. Additional Resources Meet Six Paralympians Preparing for the 2024 Paris Games What is ataxia and cerebellar or spinocerebellar degeneration? New Research Gives Hope to Patients with Inherited Ataxias Friedreich's Ataxia Research Alliance Other Brain & Life Episodes on this Topic Paralympian Jamal Hill on Winning Bronze with Charcot-Marie-Tooth Olympic Swimmer Rowdy Gaines on His Career and Guillain-Barré Syndrome BMX Athlete Josh Perry's Perseverance Living with Brain Tumors We want to hear from you! Have a question or want to hear a topic featured on the Brain & Life Podcast? · Record a voicemail at 612-928-6206 · Email us at BLpodcast@brainandlife.org Social Media: Guests: Helen Kearney @HelenKearneyIRL; Dr. Sub Subramony @fixelinstitute Hosts: Dr. Daniel Correa @neurodrcorrea; Dr. Katy Peters @KatyPetersMDPhD
Join me, David DeHaas of Living Waters Wellness Center as I delve into the hidden dangers of chemicals in food and their profound impact on health. This episode opens with a discussion on the recent controversy involving football players Travis and Jason Kelce's and their promotion of cereals containing toxins like Red and Yellow dye and other toxic ingredients. I explain how chemicals can accumulate over time, leading to severe health issues such as tumors and cancer.Drawing from My personal experience, I share my own health struggles caused by consuming sodas, toxic cereals and fast food which led to to serious illnesses including psoriasis, hives, fungus, brain fog, severe fatigue, joint and muscle pain and cancer. We look at studies recently published on the types of Diets that helped improve health the most. So what diet is best? Feingold DietFood Avoidance (based upon allergy testing)Low SugarGluten Free and Casein FreeChemical AvoidanceKeto This discussion extends to those suffering from brain fog and other chemical-related health issues, highlighting the critical link between gut health and brain function.In my reference of Dr. Andy Wakefield's Protocol 7 movie I share a personal story of recovery from autism through diet. I emphasize the presence of harmful chemicals like glyphosate in our foods, contributing to various health problems, including gender dysphoria and gut issues. The conversation also covers the growing trend of gluten-free products and the importance of detoxification for brain health.Discover how our 10-day healing retreat at Living Waters Wellness Center can help you cleanse and detoxify your body, open detox pathways, and facilitate natural healing. For more information, visit livingwaterscleanse.com and watch our video on the natural laws of healing. Transform your health from within with our expert guidance and support.Support the Show.Ready for your healing journey?Visit our website: www.LivingWatersCleanse.com Or give us a call at: (208) 378-9911Stem Cell Activation Patches:www.StemCellPatch.netGet your Supplements and Natural Body Products Here:www.livingwaterscleanse.com/supplementsQI-Shield EMF Devices:Protect your whole home or office with a touric shield from EMF's. 1. QI Shield Covers 16'x16' 2. QI Home Covers 50' x 50' 3. QI Max Covers 250'x250'Click on link and enter Livingwaters in discount code section during checkout Magnesium Soaks:Follow us on our socials: Living Waters Wellness CenterBitChute: www.bitchute.com/livingwaterswellnessRumble: www.rumble.com/livingwaters...
Dr Chris Smith and the Naked Scientist team present the latest science news, analysis and breakthroughs, In this week's episode….are we getting closer to tackling the neurological disease that claimed the life of Rugby League legend Rob Burrow? How a small carbon sponge could play a big part in removing carbon dioxide from the atmosphere and we'll be finding out how a rare condition can cause some teetotallers to get drunk.Plus we take a deep look at what a new experiment is revealing about dark matter and dark energy out in space. Get the podcast from the BBC Sounds app.
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The Real Truth About Health Free 17 Day Live Online Conference Podcast
Guest Sergiu Pasca is a physician-scientist who turns skin cells into stem cells and then into brain tissues he calls “organoids” and “assembloids” in order to study psychiatric and neurological illness in a dish instead of in living human beings. With this knowledge, Pasca hopes to develop new treatments for conditions ranging from schizophrenia and autism spectrum disorders to chronic pain, he tells host Russ Altman in this episode of Stanford Engineering's The Future of Everything podcast.Episode Reference Links:Sergiu's Lab: Pasca LabSergiu's Stanford Profile: WebsiteCenter at Stanford Sergiu Leads: Stanford Brain OrganogenesisSergiu's recently published paper: Antisense Oligonucleotide Therapeutic Approach for Timothy SyndromePaper by Shinya Yamanaka Sergiu discusses: Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast CulturesConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads or Twitter/XConnect with School of Engineering >>> Twitter/XChapters:(00:00:00) IntroductionRuss introduces guest, Sergiu Pasca, professor of Psychiatry and Behavioral Sciences at Stanford University.(00:02:43) The Science of Growing Brain Tissue from Skin CellsThe process of developing brain organoids from skin cells and the potential medical applications of these models.(00:03:59) Enhancing Neurological Research ToolsAdvancing the complexity of brain models to include various brain structures and their applications in modeling diseases.(00:07:20) Introduction of AssembloidsIntroduction to assembloids, detailing how combining different organoids can mimic complex brain structures(0015:58) Testing Therapeutics Using Humanized ModelsThe innovative approach of using humanized rat models to test neurological therapies and drugs.(00:21:03) Complex Circuit Modelling for Disease UnderstandingThe current capabilities of modeling complex brain circuits and their relevance in understanding the neural pathways involved in diseases.(00:23:36) The Future of Pain Modelling and Drug TestingHow assembled brain cells can model pain perception and response, leading to potential new treatments for chronic pain and psychiatric disorders(00:27:46) Ethical Considerations and Public EngagementEthical concerns related to creating brain-like tissues and the importance of public engagement in scientific research.(00:32:01) Future Directions and Global CollaborationThe future of brain organogenesis research and the potential impacts on treating neurological and psychiatric conditions.(00:34:05) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads or Twitter/XConnect with School of Engineering >>> Twitter/X
Ever wondered how the teeming world within our gut impacts everything from our mood to our metabolism? Today, we sit down with microbiome expert Dr. Colleen Cutcliffe, PhD to explore the hidden universe of our gut health. We unravel the complexities of the microbiome, emphasizing the importance of bacteria, viruses, and fungi in metabolizing the food we eat. Colleen shines a light on the common misconceptions about probiotics, prebiotics, and postbiotics, and why selecting high-quality supplements is crucial for optimal gut health. Together, we investigate the powerful influence of gut health on metabolic control and discuss the surprising connection between our gut and brain through the gut-brain axis. Follow Pendulum @pendulumlifeco Follow Chase @chase_chewning ----- In this episode we discuss... (00:00) Basic Understanding Gut Health and Microbiome (13:17) What to Look For When Supplementing; What Works and What is a Waste of Your Money (16:50) Innovation (or lack thereof) of Gut Health Standards (24:16) Most Important Microbiome Strains (34:52) The Connection Between Gut Health and Metabolism (45:52) Gut Health Impact on Mental Well-Being (55:43) Gut Connection to Neurological Diseases (58:59) Ever Forward ----- Episode resources: Save 20% on any Pendulum gut health or metabolic health product with code EVERFORWARD at https://www.PendulumLife.com Watch and subscribe on YouTube
This week, I welcomed David Perlmutter, MD on my show to discuss the impact of diet and lifestyle on neurological diseases, specifically Parkinson's and Alzheimer's. In our conversation, Dr. Perlmutter, known as the empowering neurologist, shares the profound connections between diet, lifestyle, and neurological diseases such as Alzheimer's, Parkinson's, and metabolic conditions like diabetes and obesity. Drawing from his extensive experience, he shares fascinating insights into innovative treatments, such as utilizing glutathione injections to alleviate symptoms in Parkinson's patients, and exploring avenues to enhance mitochondrial function to combat a spectrum of neurological diseases. Beyond treatment modalities, our discussion extends to the importance of minimizing exposure to toxins within our living spaces. From laundry practices to water consumption and even the materials of our drinking containers, Dr. Perlmutter underscores the significance of mindful choices in our day-to-day lives. We also explore the importance of diet, exercise, and stress management as crucial strategies for disease prevention and management. Dr. Perlmutter is a Board-Certified Neurologist and six-time New York Times bestselling author. He serves as a member of the Editorial Board for the Journal of Alzheimer's Disease and has published extensively in peer-reviewed scientific journals including Archives of Neurology, Neurosurgery, and The Journal of Applied Nutrition. Dr. Perlmutter's books have been published in 32 languages and include the #1 New York Times bestseller Grain Brain: The Surprising Truth About Wheat, Carbs, and Sugar, with over 1 million copies in print. 00:00 The Impact of Diet on Metabolic Diseases 00:30 Introducing Dr. David Perlmutter: A Renowned Neurologist 02:15 Exploring Parkinson's Disease: Causes and Treatments 05:26 The Role of Glutathione in Parkinson's and Detoxification 07:20 Historical Perspectives and Modern Understanding of Parkinson's 08:12 The Environmental Factors Contributing to Parkinson's 20:21 Strategies for Reducing Exposure and Enhancing Detoxification 21:21 The Microbiome's Connection to Parkinson's and Other Root Causes 25:20 Practical Tips for Minimizing Toxin Exposure and Boosting Detoxification 33:54 The Power of Infrared Saunas for Detoxification 34:38 Exploring the Link Between Toxins and Alzheimer's 37:07 Preventive Measures and Lifestyle Changes for Alzheimer's 38:55 The Role of Physical Activity in Reducing Alzheimer's Risk 40:54 Innovative Treatments and the Future of Parkinson's Therapy 46:33 Understanding Mitochondrial Dysfunction and Its Impact 49:10 The Surprising Influence of Uric Acid on Health 59:38 Optimizing Nitric Oxide Levels for Better Health 01:07:14 Leveraging Hyperbaric Oxygen Therapy for Mitochondrial Function 01:09:01 Practical Health Tips from a Neurologist Connect with Amy Myers, MD Website: https://www.amymyersmd.com/ Instagram: https://www.instagram.com/dramymyers YouTube: https://www.youtube.com/@AmyMyersMD/featured Newsletter: https://www.amymyersmd.com/ec/guide-to-leaky-gut Facebook: https://www.facebook.com/AmyMyersMD Twitter: https://twitter.com/AmyMyersMD Pinterest: https://www.pinterest.com/amymyersmd/ Connect with Dr. David Perlmutter https://www.linkedin.com/in/david-perlmutter-md-6a38b930/
The Real Truth About Health Free 17 Day Live Online Conference Podcast
Episode Summary: In this eye-opening episode, Dr. Kristin Hieshetter tackles the challenging topic of declining life expectancy in the USA and the alarming rates of chronic diseases among children. She delves into the controversial issue of glyphosate, a ubiquitous herbicide, and its prevalence in our diets. This episode offers a deep dive into the health implications of consuming commonly found grains and the powerful effect that dietary choices have on our overall health. Dr. Hieshetter touches upon the historical increase in processed foods and a sedentary lifestyle as contributing factors to the deterioration of public health. Alongside these insights, she also provides a wealth of knowledge about avoiding harmful substances like glyphosate, advocating for organic food consumption, and embracing grain-free lifestyles to mitigate the risk of inflammation and chronic disease. Listeners can expect to be both educated and inspired as Dr. Hieshetter cites various studies and experts to back her claims, painting a clear picture of the detrimental effects of modern agricultural practices and food processing on human health. She doesn't just outline problems but offers robust solutions, advice and allies in the health space to pave the way for improved dietary habits and a return to functional health. Key Takeaways: The life expectancy in the USA has significantly declined, with chronic diseases in children rising at unprecedented rates. Glyphosate, a widely used herbicide, has been linked to a spectrum of health issues, including cancer and neurological effects. A diet rich in grains can lead to "leaky gut syndrome," causing inflammation and a host of autoimmune and neurological disorders. Organic fruits and vegetables can reduce pesticide exposure by a staggering 96%. A call to action to embrace dietary changes, avoid processed foods and grains, and to consume low-lectin, organic food for optimal health. Notable Quotes: "We are walking around in the most amazing, intelligent, responsive, adapting, and aware system in the world, the human body." "Grains are full of lectins, which we're going to get into. They're full of glyphosate. They can create celiac disease, irritable bowel syndrome, inflammation in the body." "They use [glyphosate] as a chelator. It binds the nutrients and vitamins, and they decide to use it on our food. In fact, to the tune of 280,000,000 pounds a year, in the United States of America." "When your gut leaks, your brain leaks. If you're eating this stuff, you are enhancing the likelihood of developing Alzheimer's, Parkinson's, and dementia." "Let's get ahead of this, right? We need to consume only organic fruits and vegetables. If you do just that one thing, you can eliminate about 96% of your total pesticide exposure." Resources: Moms Across America Website: Moms Across America "Wheat Belly Diet" and "Undoctored" by William Davis, M.D. "Grain Brain" by David Perlmutter, M.D. "Primal Body, Primal Mind" and "Primal Fat Burner" by Nora Gedgaudas; edited by Dan Murphy, D.C. "The Plant Paradox" and "The Longevity Paradox" by Steven Gundry, M.D. "The Hacking of the American Mind" by Robert Lustig, M.D. Tune into "Functional Health Radio" for more empowering episodes that give you the control and knowledge needed to achieve optimal health. Join Dr. Kristin Hieshetter each week as she continues to explore and discuss the mechanisms that influence our health and well-being in today's complex world. Stay informed, inspired, and in charge of your health journey.
Links: Go to episode page (with episode resources) Subscribe to PREMIUM Get the Sigma email newsletter See Sigma's recommended resources About This Episode: Alzheimer's disease has a profound impact on individuals, families, and societies worldwide. As a progressive neurodegenerative disease, it not only robs individuals of their cognitive abilities but also places an immense emotional and economic burden on caregivers. Mechanistically, the causes of Alzheimer's are incredibly complex and not fully understood. And in terms of treatment, the landscape appears challenging. Drug discovery efforts for dementias, including Alzheimer's, have faced setbacks, leaving a void in effective treatments. Consequently, attention has shifted toward preventive strategies, including dietary patterns. From a prevention standpoint, both genetics and lifestyle should be considered. Which throws up many interesting questions… To what extent do genetic factors contribute to Alzheimer's risk compared to lifestyle choices, and how does this interaction influence disease development? What role does lifestyle play in Alzheimer's risk, and is there evidence supporting the influence of specific nutrients on cognitive health? How do diet patterns impact Alzheimer's risk? Are there discernible risk differences associated with specific dietary choices, and how do these interact with genetic factors, such as the ApoE genotype? In this episode, Drs. Ayesha Sherzai and Dean Sherzai are on the podcast to answer these questions and discuss this topic in more depth. About The Guests: Dr. Ayesha Sherzai is a neurologist and co-director of the Alzheimer's Prevention Program at Loma Linda University, where she leads the Lifestyle Program for the Prevention of Neurological Diseases. She completed a dual training in Preventative Medicine and Neurology at Loma Linda University, and a fellowship in Vascular Neurology and Epidemiology at Columbia University. She is also a trained plant-based culinary artist. Dr. Dean Sherzai is co-director of the Alzheimer's Prevention Program at Loma Linda University. Dean trained in Neurology at Georgetown University School of Medicine, and completed fellowships in neurodegenerative diseases and dementia at the National Institutes of Health and UC San Diego. He also holds a PhD in Healthcare Leadership with a focus on community health from Andrews University.
Arts On Prescription: What if your doctor prescribed an arts-based treatment for what ails you and your health insurance paid for it. YEAH RIGHT! Actually, Yeah, right, and REALLY! In this episode we learn all about it in Arts on Prescription: A Field Guide for U. S. CommunitiesBIO'sDr. Tasha Golden directs research for the International Arts + Mind Lab at Johns Hopkins Medicine. As a national leader in arts + public health, Dr. Golden studies the impacts of arts & culture, music, aesthetics, and social norms on well-being, health research, and professional practice. She has authored many publications related to arts and health, served as an advisor on several national health initiatives, and is adjunct faculty for the University of Florida's Center for Arts in Medicine.In addition to her research, Golden is a career artist and entrepreneur. As singer-songwriter for the critically acclaimed band Ellery, she toured full-time in the U.S. and abroad, and her songs appear in feature films and TV dramas (ABC, SHOWTIME, FOX, NETFLIX, etc). She is also a published poet and has taught university courses in public health as well as in writing, rhetoric, and literature. Holding a Ph.D. in Public Health Sciences, Dr. Golden draws on her diverse background to develop innovative, interdisciplinary presentations and partnerships that advance health, health equity, creativity, and well-being.Dr. Golden is also the founder of Project Uncaged: an arts-based health intervention for incarcerated teen women that amplifies their voices in community and policy discourses. These young folx are among her greatest teachers.Jill Sonke, PhD, is director of research initiatives in the Center for Arts in Medicine at the University of Florida (UF), director of national research and impact for the One Nation/One Project initiative, and co-director of the EpiArts Lab, a National Endowment for the Arts Research Lab. She is an affiliated faculty member in the UF School of Theatre & Dance, the Norman Fixel Institute for Neurological Diseases, the Center for African Studies, the STEM Translational Communication Center, and the One Health Center, and is an editorial board member for Health Promotion Practice journal. She served in the pandemic as a senior advisor to the US Centers for Disease Control and Prevention (CDC) Vaccine Confidence and Demand Team on the COVID-19 Vaccine Confidence Task Force and currently serves on the steering committee of the Jameel Arts & Health Lab, established by the World Health Organization (WHO), the Steinhardt School at New York University, Community Jameel, and CULTURUNNERS. With 28 years of experience and leadership in the field of arts in health and a PhD in arts in public health from Ulster University in Northern Ireland, Jill is active in research and policy advocacy nationally and internationally. She is an artist and a mixed methods researcher with a current focus on population-level health outcomes associated with arts and cultural participation, arts in public health, and the arts in health communication. Notable MentionsNotable MentionsArts On Prescription: A Field Guide for US Communities.: A roadmap for communities to develop programs that integrate arts, culture, and nature resources into local health and social care systems. prescription
In this episode, In Vivo speaks to Bruce Leuchter, CEO of Neurvati Neurosciences, about ways clinical drug development in rare neurologic diseases is being held back and what can be done to make the process more efficient and successful.
Vivian DeWoskin, Chief Commercial Officer at NeuraLight, focuses on developing solutions for diagnosing, monitoring and treating neurodegenerative diseases using oculometric data. Using computer vision and deep learning techniques, data from measuring eye position and movement can provide biomarkers for early detection and insights into neurological health. This non-invasive technology is being tested in the PALOMA study, a longitudinal study of Parkinson's patients designed to develop one biomarker as a monitoring and assessment tool. Vivian explains, "The reason that this works or theoretically works is that there's a very well-characterized ocular motor system. We know a lot about the ocular motor system and the relationship between eye movement and different parts of the brain. When we talk about oculometrics, we're not just measuring one thing. We're talking about measuring multiple aspects of eye movement and function. Those different aspects are related to a variety of different neural pathways. So, in the context of neurodegenerative disease, we can see certain characteristic changes in how a patient's eyes move or function as a direct result of the degeneration happening in particular areas of the brain." "The distinct signal that we can get from these different types of oculometrics, from different brain regions, gives us a really powerful tool to be able to use for a variety of purposes like we just described. For diagnosing patients early, potentially differentiating between very similar conditions or conditions that appear similar in their outward presentation of symptoms but have a different disease pathology in the brain. We're excited about this methodology for being able to offer us a variety of really exciting tools that ultimately will help us develop better therapeutics for patients and help benefit patients in the long run." #NeuraLight #OculometricData #EyeMovement #ParkinsonsDisease #NeurologicalDiseases #DigitalBiomarkers neuralight.ai Download the transcript here
Vivian DeWoskin, Chief Commercial Officer at NeuraLight, focuses on developing solutions for diagnosing, monitoring and treating neurodegenerative diseases using oculometric data. Using computer vision and deep learning techniques, data from measuring eye position and movement can provide biomarkers for early detection and insights into neurological health. This non-invasive technology is being tested in the PALOMA study, a longitudinal study of Parkinson's patients designed to develop one biomarker as a monitoring and assessment tool. Vivian explains, "The reason that this works or theoretically works is that there's a very well-characterized ocular motor system. We know a lot about the ocular motor system and the relationship between eye movement and different parts of the brain. When we talk about oculometrics, we're not just measuring one thing. We're talking about measuring multiple aspects of eye movement and function. Those different aspects are related to a variety of different neural pathways. So, in the context of neurodegenerative disease, we can see certain characteristic changes in how a patient's eyes move or function as a direct result of the degeneration happening in particular areas of the brain." "The distinct signal that we can get from these different types of oculometrics, from different brain regions, gives us a really powerful tool to be able to use for a variety of purposes like we just described. For diagnosing patients early, potentially differentiating between very similar conditions or conditions that appear similar in their outward presentation of symptoms but have a different disease pathology in the brain. We're excited about this methodology for being able to offer us a variety of really exciting tools that ultimately will help us develop better therapeutics for patients and help benefit patients in the long run." #NeuraLight #OculometricData #EyeMovement #ParkinsonsDisease #NeurologicalDiseases #DigitalBiomarkers neuralight.ai Listen to the podcast here
Imagine an electrical storm in your brain, a power surge that passes through delicately wired neural circuits, making thousands of cells all activate at once. Depending on where it starts and where it travels in the brain, it could make your muscles seize up. It could create hallucinatory visions or imaginary sounds. It could evoke deep anxiety or a sense of holiness, or it could even make you lose consciousness. This kind of electrical storm is what we call a seizure. If your brain is prone to seizures, we call it epilepsy. This week we're joined by Fiona Baumer, a Stanford pediatric neurologist and researcher, to dive into this misunderstood and often stigmatized disorder. In addition to treating children with seizure disorders, Dr. Baumer conducts research at the Koret Human Neurosciences Community Laboratory at Wu Tsai Neuro. There she uses transcranial magnetic stimulation (TMS) paired with EEG, to stimulate and read out patterns of activity moving across the brain in children with epilepsy. In our conversation, we discuss what neuroscience has taught us about where seizures come from and how new technologies are giving us insights not only into potential treatments for the disorder, but also providing a window into some of the brain's hidden patterns of activity. We're taking a break over the next few weeks. We'll return with new episodes in the new year. In the meantime, if you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. LinksBaumer's Pediatric Neurostimulation LaboratoryNorthern California Epilepsy FoundationThanks for listening! Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.
For decades, researchers, clinicians, and industry professionals have continued to study and optimize deep brain stimulation (DBS) with the goal of providing the best possible personalized treatment for Parkinson's disease (PD) and other neurological conditions. In this episode, Dr. Michael Okun joins us to discuss his research and some of the recent advances in deep brain stimulation and other areas. He draws from his extensive research and clinical experience applying DBS and neuromodulation therapies for patients with PD, Tourette syndrome, tic disorders, dystonia, essential tremor, and obsessive-compulsive disorder. Michael is co-founder and co-director of the Norman Fixel Institute for Neurological Diseases at the University of Florida, as well as Medical Advisor for the Parkinson's Foundation. He is a board-certified neurologist, movement disorders specialist, neuroscientist, author, and an expert on deep brain stimulation and neuromodulation for movement disorders. This podcast is geared toward researchers and clinicians. If you live with Parkinson's or have a friend or family member with PD, listen to The Michael J. Fox Foundation Parkinson's Podcast. Hear from scientists, doctors and people with Parkinson's on different aspects of life with the disease as well as research toward treatment breakthroughs at https://www.michaeljfox.org/podcasts.
Dr. Kavita Desai is a highly respected expert in her field, specializing in the unique healthcare needs of menopausal women. In this interview, she shares her invaluable expertise on how to prevent and manage neurological diseases that often affect women during this stage of life.
Please support the show so that I can continue to speak up by choosing one or all of the following options - Buy me a coffee If you want to make a one off donation. Join my Substack To access additional content, you can upgrade to paid, from just £3.50 a month. To sponsor the Doc Malik Podcast contact us at hello@docmalik.com About this interview: Dr Natasha Campbell-McBride is the creator of the GAPS concept and the GAPS Diet. You can find her full bio on her website links below. Natasha graduated with honours as a medical doctor in 1984 in Russia and in the following years gained postgraduate degrees in neurology and in human nutrition. She is the author of several books: 1 Gut And Psychology Syndrome: Natural Treatment of Autism, ADHD, Dyslexia, Depression and Schizophrenia.Vegetarianism Explained. 2 Making an Informed Decision. Put Your Heart in Your Mouth! 3 What Really is Heart Disease and What Can We Do to Prevent and Even Reverse it. 4 Gut And Physiology Syndrome. Natural Treatment for Allergies, Autoimmune Illness, Arthritis, Gut Problems, Fatigue, Hormonal Problems, Neurological Disease and more. Natasha is also an organic regenerative farmer. In this podcast I talk to Natasha about what made her deviate from allopathic medicine, what inspired her to formulate her GAPS diet, and what her thoughts are on achieving and maintaining optimal health. I really enjoyed this conversation and hope you will too. Do let me know and comment below. Enjoy x Links - Website GAPSDr NatashaGAPS trainingGAPS online conference Twitter Natasha Campbell-McBride About Doc Malik: Orthopaedic surgeon Ahmad Malik is on a journey of discovery when it comes to health and wellness. Through honest conversations with captivating individuals, Ahmad explores an array of topics that profoundly impact our well-being and health. You can follow us on social media, we are on the following platforms: Twitter Ahmad | Twitter Podcast | Instagram Ahmad | Instagram Podcast
Kay Toombs is associate professor emerita of philosophy at Baylor University in Texas. In her work she explores the ways in which contemporary values and the context in which we live our lives impact our efforts to develop a sustainable culture and to form caring communities. In her work related to illness, disability and healthcare, she combines her training in philosophy with her experience of living with neurological disease to reflect on the experience of illness and disability, the care of the chronically and terminally ill, the relationship between health care professionals and patients, and the meaning of suffering and healing, both in the context of Western culture and within the context of intentional Christian community. Explore Books by Kay Toombs:www.homesteadheritage.com/books; www.amazon.com/booksThe Meaning of Illness: A Phenomenological Account of the Different Perspectives of Physician and PatientHow Then Should We Die: Two Opposing Responses to the Challenges of Suffering and DeathLiving at the Boundary, Healing and Incurable IllnessThe Human Dimension of Sustainable Culture Write to Kay Toombs KEY QUESTIONS:What can God show us through disability and serious illness?How can Christians turn from radical autonomy to relationship with God and others?How can Christian community create a sustainable, caring culture?How can faith enrich our experience of caregiving? KEY SCRIPTURES:Psalm 61:1–2: “Hear my cry, O God; listen to my prayer. From the ends of the earth I call to you; I call as my heart grows faint; lead me to the rock that is higher than I.”Psalm 133:1: “How good and pleasant it is when God's people live together in unity!”John 15:13: “Greater love has no one than this: to lay down one's life for one's friends.” ------- Find more encouragement on Joni Eareckson Tada's Sharing Hope podcast and daily devotional.Follow Joni and Friends on TikTok, Instagram, Facebook, and YouTube.Your support makes this podcast possible!Joni and Friends envisions a world where every person with a disability finds hope, dignity, and their place in the body of Christ. Founded by Joni Eareckson Tada, we provide Christ-centered care through Joni's House, Wheels for the World, and Retreats and Getaways, and offer disability ministry training.
Feel Olivia's passion, resilience, and determination shine through as she shares her insights on personal growth, overcoming challenges, advocating for oneself, and making choices that align with one's purpose. You will be left inspired and motivated to embrace your own transformations and live life on your own terms, creating a positive impact along the way.
In this must-see episode, Dr. Natasha claims you can reverse “any chronic or autoimmune disease” by addressing gut health and she has the research and case studies to prove it. Farmer Joel and Dr. Sina chatted with her about these findings, as well as the role of vibrational frequencies in choosing healing foods, thoughts and intentions.Access the entire episode here: https://beyondlabels.supportingcast.fm/About Natasha Campbell-McBride, M.D.MMedSci (neurology), MMedSci (nutrition)Dr Campbell-McBride is the creator of the GAPS concept and the GAPS Diet. Please read the full bio on her website www.gaps.me. Dr Campbell-McBride graduated with honors as a medical doctor in 1984 in Russia and in the following years gained postgraduate degrees in neurology and in human nutrition.She is the author of several books: Gut And Psychology Syndrome: Natural Treatment of Autism, ADHD, Dyslexia, Depression and Schizophrenia.Vegetarianism Explained. Making an Informed Decision. Put Your Heart in Your Mouth! What Really is Heart Disease and What Can We Do to Prevent and Even Reverse it. Gut And Physiology Syndrome. Natural Treatment for Allergies, Autoimmune Illness, Arthritis, Gut Problems, Fatigue, Hormonal Problems, Neurological Disease and more.Dr Natasha is an organic regenerative farmer and a popular keynote speaker at many professional conferences worldwide.Follow on InstagramFollow on TwitterSubscribe on YouTubeFind Joel Here: www.polyfacefarms.comFind Sina Here: www.drsinamccullough.comDisclaimer: The information provided by Joel Salatin and Sina McCullough, PhD is not intended to prevent, diagnose, treat, or cure any disease. The information provided in the podcasts, videos, and show descriptions is for educational purposes only. It is not intended to diagnose or treat any medical or psychological condition. The information provided is not meant to prevent, treat, mitigate or cure such conditions. The information provided is not medical advice nor is it designed to replace advice, information, or prescriptions you receive from your healthcare provider. Consult your health care provider before making any changes to your diet, medication, or lifestyle. Proceed at your own risk.Joel Salatin and Sina McCullough, Ph.D. specifically disclaim any liability, loss, or risk, personal or otherwise, that may be incurred as a consequence, directly or indirectly, of the use and application of any of the contents of their YouTube channel, Podcast, websites, books, Facebook pages, or any of the content during consulting sessions or speaking engagements. Proceed at your ow
Unlike cancer, brain diseases like epilepsy, Alzheimer's disease, or depression don't tend to have easily measured biomarkers that could help doctors tailor treatments, or that could help researchers develop more effective drugs. So in neurology and psychiatry, the precision medicine revolution hasn't really arrived yet. But Beacon Biosignals, where Harry's guest Jacob Donoghue is the co-founder and CEO, is trying to change all that. Beacon is focused on making electroencephalography into a more reliable and useful data source for diagnosing and treating neurological disease. EEG is a non-invasive way to measure electrical activity in the brain, and it's been a common medical tool for almost 100 years. But takes a lot of training for a human doctor to interpret an EEG correctly. It's slow, it's expensive, and it's a bit of a dark art—all of which makes it the perfect candidate for machine learning analysis. Donoghue says the goal at Beacon Biosignals is to use computation to get more value out of existing EEG data. By peering deeper into the data, he thinks it should be possible to identify subtypes of problems like epilepsy or Alzheimer's, and help neurologists understand which patients will respond best to which therapies. On top of that, better EEG measurements could also give drug developers and regulators more clinical endpoints to measure when they're trying to evaluate the safety and efficacy of new drugs for CNS diseases. If Beacon's vision comes true, the precision medicine revolution might finally start to reach the brain.For a full transcript of this episode, please visit our episode page at http://www.glorikian.com/podcast Please rate and review The Harry Glorikian Show on Apple Podcasts! Here's how to do that from an iPhone, iPad, or iPod touch:1. Open the Podcasts app on your iPhone, iPad, or Mac. 2. Navigate to The Harry Glorikian Show podcast. You can find it by searching for it or selecting it from your library. Just note that you'll have to go to the series page which shows all the episodes, not just the page for a single episode.3. Scroll down to find the subhead titled "Ratings & Reviews."4. Under one of the highlighted reviews, select "Write a Review."5. Next, select a star rating at the top — you have the option of choosing between one and five stars. 6. Using the text box at the top, write a title for your review. Then, in the lower text box, write your review. Your review can be up to 300 words long.7. Once you've finished, select "Send" or "Save" in the top-right corner. 8. If you've never left a podcast review before, enter a nickname. Your nickname will be displayed next to any reviews you leave from here on out. 9. After selecting a nickname, tap OK. Your review may not be immediately visible.That's it! Thanks so much.
My guest today is Nita Farahany. Nita is a professor of Law and Philosophy at Duke Law School. She is the founding director of the Duke Science and Society. She is the faculty chair of the Duke MA in Bioethics and Science Policy and Principal Investigator at slap lab. In 2010, she was appointed by President Obama to the Presidential Commission for the Study of Bioethical Issues where she served until 2017. She's an appointed Member of the National Advisory Council for the National Institute for Neurological Disease and Stroke and she is a past president of the International Neuroethics Society. This is only a small slice of her bio.The topic of this conversation is mind reading, and I don't mean trying to guess what's in somebody's head. I mean actual technology that scans your brain and reliably conveys what you are thinking or feeling. Now, this seemed like science fiction to me, but Nita convinced me in this conversation that this technology is already here, and there are a host of ethical questions relating to privacy and other things.Nita and I talk about how EEG scans can give us information about our minds. We talk about the relationship between EEG scans and classical questions in the philosophy of mind, such as consciousness, as well as free will. We talk about the uses of mind-reading technology in criminal investigations, which has already happened. We talk about the current uses of mind-reading tech in Chinese factories. And yes, that is already happening too. We talk about tattoos that can pick up your brain activity. And once again, that already exists. We talk about the combination of artificial intelligence and mind-reading tech and what that promises for the future. We talk about whether excellent liars would be able to pass mind-reading technology. We also talk about how mind-reading tech has even been used to tell whether couples are in love. I really hope you enjoy this conversation as much as I did.
My guest today is Nita Farahany. Nita is a professor of Law and Philosophy at Duke Law School. She is the founding director of the Duke Science and Society. She is the faculty chair of the Duke MA in Bioethics and Science Policy and Principal Investigator at slap lab. In 2010, she was appointed by President Obama to the Presidential Commission for the Study of Bioethical Issues where she served until 2017. She's an appointed Member of the National Advisory Council for the National Institute for Neurological Disease and Stroke and she is a past president of the International Neuroethics Society. This is only a small slice of her bio. The topic of this conversation is mind reading, and I don't mean trying to guess what's in somebody's head. I mean actual technology that scans your brain and reliably conveys what you are thinking or feeling. Now, this seemed like science fiction to me, but Nita convinced me in this conversation that this technology is already here, and there are a host of ethical questions relating to privacy and other things. Nita and I talk about how EEG scans can give us information about our minds. We talk about the relationship between EEG scans and classical questions in the philosophy of mind, such as consciousness, as well as free will. We talk about the uses of mind-reading technology in criminal investigations, which has already happened. We talk about the current uses of mind-reading tech in Chinese factories. And yes, that is already happening too. We talk about tattoos that can pick up your brain activity. And once again, that already exists. We talk about the combination of artificial intelligence and mind-reading tech and what that promises for the future. We talk about whether excellent liars would be able to pass mind-reading technology. We also talk about how mind-reading tech has even been used to tell whether couples are in love. I really hope you enjoy this conversation as much as I did. Learn more about your ad choices. Visit megaphone.fm/adchoices