Podcasts about friedman brain institute

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Latest podcast episodes about friedman brain institute

The Michael J. Fox Foundation Parkinson's Podcast
The Autophagy-Lysosomal Pathway and Development of Relevant PD Biomarkers with Zhenyu Yue

The Michael J. Fox Foundation Parkinson's Podcast

Play Episode Listen Later Aug 20, 2024 31:54


Though existing evidence supports that dysfunction in the clearing of cellular debris plays an important role in the development of Parkinson's disease, many unanswered questions remain regarding the mechanisms of the autophagy-lysosomal pathway involved in this process. In particular, research in the field has been limited by a lack of reliable, quantitative tests for monitoring autophagy-lysosome activity. In this interview, Dr. Zhenyu Yue describes his research investigating the cellular and molecular mechanisms for Parkinson's disease and other neurodegenerative diseases, focusing on their work examining the regulation of the autophagy-lysosomal pathway, potential therapeutic targets, and MJFF-funded research that aims to develop sensitive, robust autophagy-lysosome assays to facilitate the discovery of biomarkers for PD using stem cell-derived neurons and biofluids. Zhenyu is the Aidekman Research Professor in the Department of Neurology and Friedman Brain Institute at the Icahn School of Medicine at Mount Sinai. He is also the Director of the Center of Parkinson's Disease Neurobiology and Director of Basic Research of Movement Disorders at Mount Sinai.This podcast is geared toward researchers and clinicians. If you live with Parkinson's or have a friend or family member with PD, listen to The Michael J. Fox Foundation Parkinson's Podcast. Hear from scientists, doctors and people with Parkinson's on different aspects of life with the disease as well as research toward treatment breakthroughs at https://www.michaeljfox.org/podcasts.

The Parkinson’s Research Podcast: New Discoveries in Neuroscience
21: The Autophagy-Lysosomal Pathway and Development of Relevant PD Biomarkers with Zhenyu Yue

The Parkinson’s Research Podcast: New Discoveries in Neuroscience

Play Episode Listen Later Aug 20, 2024 31:54


Though existing evidence supports that dysfunction in the clearing of cellular debris plays an important role in the development of Parkinson's disease, many unanswered questions remain regarding the mechanisms of the autophagy-lysosomal pathway involved in this process. In particular, research in the field has been limited by a lack of reliable, quantitative tests for monitoring autophagy-lysosome activity. In this interview, Dr. Zhenyu Yue describes his research investigating the cellular and molecular mechanisms for Parkinson's disease and other neurodegenerative diseases, focusing on their work examining the regulation of the autophagy-lysosomal pathway, potential therapeutic targets, and MJFF-funded research that aims to develop sensitive, robust autophagy-lysosome assays to facilitate the discovery of biomarkers for PD using stem cell-derived neurons and biofluids. Zhenyu is the Aidekman Research Professor in the Department of Neurology and Friedman Brain Institute at the Icahn School of Medicine at Mount Sinai. He is also the Director of the Center of Parkinson's Disease Neurobiology and Director of Basic Research of Movement Disorders at Mount Sinai.This podcast is geared toward researchers and clinicians. If you live with Parkinson's or have a friend or family member with PD, listen to The Michael J. Fox Foundation Parkinson's Podcast. Hear from scientists, doctors and people with Parkinson's on different aspects of life with the disease as well as research toward treatment breakthroughs at https://www.michaeljfox.org/podcasts.

Science in Action
Unexpected black hole in our galaxy

Science in Action

Play Episode Listen Later Apr 18, 2024 31:12


A black hole just discovered in our Milky Way galaxy, weighing 33 times the mass of the Sun, and dating back to near the time of the Big Bang, gives new clues to the origins of this dark astronomical mysteries. And dancing with a Sun-like star in our galactic neighbourhood, it offers a great opportunity for astronomers to take a detailed look in coming years, as astronomer Professor Gerry Gilmore of Cambridge University tells the programme. Presenter Roland Pease has headed to the lab of Professor Ludovic Orlando in Toulouse, France where they are extracting ancient DNA from horses as part of a project called “Horsepower” - to reveal how our prehistoric ancestors tamed and domesticated these powerful animals (long after cattle and sheep) and in the process helped shape the extraordinary history of the first states of China and Mongolia. And a deep look into the mechanisms of addiction – showing how drugs of abuse, such as cocaine, hijack the neuronal pathways that had evolved to drive our innate needs such as eating and drinking. Roland hears from psychiatrist Eric J. Nestler of the Friedman Brain Institute at Icahn School of Medicine at Mount Sinai in New York, how this could one day improve addiction treatments. Presenter: Roland Pease Producer: Jonathan Blackwell Production Coordinator: Jana Bennett-Holesworth (Image: An artist's impression shows the orbits of the most massive stellar black hole in our galaxy, dubbed Gaia BH3, and a companion star. Credit: European Southern Observatory via Reuters)

Friends of Franz
The Way to a Man's Brain Is Through His Stomach with Neuroscientist Dr. Aya Osman

Friends of Franz

Play Episode Listen Later Feb 9, 2024 49:19


Over the past few years, the health and wellness space has been flooded with the concept of the "gut microbiome," or the ecosystem of microorganisms in our stomachs. Probiotics, which have become prominent on social media, are said to strengthen this bacterial community and can result in benefits like improved nutrient absorption, skin inflammation, and even mental acuity. However, this connection of the gut to the mental sphere has actually been shown in research as the "gut-brain axis" (GBA). In fact, according to a 2015 journal from the Annals of Gastroenterology, a bidirectional relationship between our gut and our brain has been shown to influence our responses to anxiety, stress, and even functions of memory through interactions with the central nervous system.We are joined today by behavioral neuroscientist, toxicologist, neuropharmacologist, and international fashion model Dr. Aya Osman. She received her BSc in Biomedical Sciences with Honors from the University of London, MSc in Toxicology focusing on the role of adenosine and glutamate receptors in cocaine addiction from the University of Surrey, and PhD in Toxicology and Neuropharmacology from the University of Surrey, where she investigated the development of brain opioid and oxytocin receptor systems in response to early life dietary manipulation. She then worked as a Toxicologist at the Centre for Radiation, Chemical, and Environmental Hazards for the governmental body Public Health England. Dr. Osman completed her postdoctoral research fellowship at the Friedman Brain Institute and the Seaver Autism Center for Research and Treatment at Icahn School of Medicine at Mount Sinai, where she now serves as an Assistant Professor, focusing on the role of gut microbiome changes in brain development and the pathophysiology of neuropsychiatric disorders.Livestream Air Date: April 25, 2023Follow Aya Osman, PhD: InstagramFollow Friends of Franz Podcast: Website, Instagram, FacebookFollow Christian Franz Bulacan (Host): Instagram, YouTubeThankful to the season's brand partners: Covry, House of M Beauty, Nguyen Coffee Supply, V Coterie, Skin By Anthos, Halmi, By Dr Mom, LOUPN, Baisun Candle Co., RĒJINS, Twrl Milk Tea, 1587 Sneakers

Stories of WiN
Dr. Kanaka Rajan

Stories of WiN

Play Episode Listen Later Nov 3, 2021 46:36


In this episode, Dakota interviews Kanaka, a Computational Neuroscientist and Assistant Professor at the Friedman Brain Institute at the Icahn School of Medicine, Mount Sinai who studies how abstract cognitive variables underlie learning, memory, and decision-making.

The Story Collider
Stories of COVID-19: Balance

The Story Collider

Play Episode Listen Later Oct 1, 2021 32:46


This week, we bring you two stories about the struggle to find balance during the COVID-19 pandemic, whether it's as a scientist, a mother, or all of the above. Part 1: Psychiatrist Xiaosi Gu studies COVID-19's impact on mental health, just as her own begins to deteriorate. Part 2: Stacey Bader Curry's family and career are thriving — until the pandemic throws it all into chaos. Dr. Xiaosi Gu is one of the foremost researchers in the area of computational psychiatry. Her research examines the neural and computational mechanisms underlying human beliefs, decision making, and social interaction in both health and disease, through a synthesis of neuroscience, cognitive science, and behavioral economics approaches. After receiving a Bachelor's degree in Psychology and Economics from Peking University in Beijing, Dr. Gu moved to New York City to pursue a Ph.D. in Neuroscience at the Icahn School of Medicine at Mount Sinai. Dr. Gu then completed her postdoctoral training in computational psychiatry at Virginia Tech and the Wellcome Trust Centre for Neuroimaging, University College London (UCL). During her time in London, she founded the world's first computational psychiatry course at UCL. Before re-joining Mount Sinai, Dr. Gu held faculty positions at the University of Texas, Dallas and UT Southwestern Medical Center. She is currently an Assistant Professor in Psychiatry and Neuroscience, and a Principal Investigator at the Friedman Brain Institute and the Addiction Institute at Mount Sinai. Stacey Bader Curry is a writer and storyteller who lives in Maine. She is an 8-time Moth Slam winner, including a Grand Slam, and has performed on PBS' Stories From the Stage, and many podcasts. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Lady Scientist Podcast
Dr. Kanaka Rajan, Computational Neuroscientist & Assistant Professor at Mt Sinai

Lady Scientist Podcast

Play Episode Listen Later Jul 8, 2021 89:54


Kanaka Rajan, Ph.D. is a Computational Neuroscientist and Assistant Professor at the Friedman Brain Institute at Mount Sinai in New York. Her research seeks to understand how the brain functions; how it learns or makes decisions. We dive into Dr. Rajan's approaches these brain 'themes' in this interview. She also walks us through the contrasts between the fields of neurobiology and artificial intelligence, and opens our minds to how our understanding of the brain has advanced over time. We learned so much and we hope you do too! Links for Kanaka: Wikipedia profile: https://en.wikipedia.org/wiki/Kanaka_... Twitter profile: https://twitter.com/rajankdr https://www.rajanlab.com This episode is sponsored by Kendall Investor Relations: https://www.kendallinvestorrelations.com HDSA Team Hope Walk: https://washington.hdsa.org/ Support the podcast: https://www.patreon.com/ladyscientist... Buy Us a Coffee: https://www.buymeacoffee.com/LSPodcast All links + merch: https://www.ladyscientistpodcast.com

Science et al
Eric Nestler: Medical Leadership 101

Science et al

Play Episode Listen Later Dec 4, 2020 49:38


Daniel interviews Eric Nestler for this episode of Science et al. The Dean for Academic Affairs and Director of the Friedman Brain Institute at the Icahn School of Medicine at Mount Sinai in New York, Eric studies drug addiction and depression, and has co-authored 4 books, one of which Daniel used to learn pharmacology. The two discuss how neuroscience and psychotherapy interact, potentially.

People Behind the Science Podcast - Stories from Scientists about Science, Life, Research, and Science Careers
566: Creating Computational Models to Determine How the Brain Accomplishes Complex Tasks - Dr. Kanaka Rajan

People Behind the Science Podcast - Stories from Scientists about Science, Life, Research, and Science Careers

Play Episode Listen Later Aug 10, 2020 41:11


Dr. Kanaka Rajan is a computational neuroscientist and Assistant Professor in the Department of Neuroscience and Friedman Brain Institute within the Icahn School of Medicine at Mount Sinai. In her research, Kanaka builds mathematical and computational models of the brain to better understand how the brain works. Her goal is to determine how the neurons and synapses of the brain work together to create complex processes like learning, memory, and decision-making. Running is a passion for Kanaka, and going for a run often helps her think more clearly. In addition, she enjoys sketching urban scenes and scientific themes. She received her bachelor’s degree in Industrial Biotechnology from Anna University in India, her M.S. in Neuroscience from Brandeis University, and her Ph.D. in Neuroscience from Columbia University. Kanaka conducted postdoctoral research as a Biophysics Theory Fellow at Princeton University before accepting her current position. She has received numerous awards and honors throughout her career, including the Sloan-Swartz Theoretical Neuroscience Postdoctoral Fellowship, Brain and Behavior Foundation Young Investigator Award, Understanding Human Cognition Scholar Award from the James McDonnell Foundation, Sloan Research Fellowship in Neuroscience, and Friedman Brain Institute Research Scholars Award from the DiSabato Family Foundation. In our interview, Kanaka shares more about her life and research.

Road to Resilience
Resilience Stories (Live!)

Road to Resilience

Play Episode Listen Later Mar 27, 2019 30:16 Transcription Available


An anxious woman’s worst fears come true. A young man grasps for a ladder out of poverty and depression. On this episode, two resilience stories told live by neuroscience PhD students at the Icahn School of Medicine at Mount Sinai. Featuring “unsanctioned” breast exams, zebra finches, and DREADDs (Google it!). These stories were performed live at the Studying the Brain storytelling event hosted by the Icahn School of Medicine's Friedman Brain Institute at El Barrio's Artspace PS109 on March 11, 2019. Music by BlueDot Sessions. Additional editing by Ben Kruse. Help us tell more great stories by completing our listener survey (http://bit.ly/2knrxzR). Enjoying the podcast? Please rate and review us on Apple Podcasts (https://apple.co/2Nve2Kt).

NeuwriteWest
Neurotalk S5E12: Eric Nestler

NeuwriteWest

Play Episode Listen Later Feb 16, 2016 53:00


In this episode, we interview Professor Eric Nestler, Professor and Chair of Neuroscience at the Mount Sinai School of Medicine, and Director of the Friedman Brain Institute at Mount Sinai. In this episode, we'll talk about the molecular basis of basis of addiction, improving animal models of depression, and being a true Yalie.

Inside The Mind of Teens and Tweens
As Marijuana Moves Towards Greater Acceptance, What is the Impact on Teens?

Inside The Mind of Teens and Tweens

Play Episode Listen Later Jan 29, 2014 9:11


We're seeing definitive moves toward the legalization of marijuana for recreational use. As the use of pot becomes normalized, what will be the impact on teens and what should parents say to their teens about its use. Follow: @rrlamourelle @bamradionetwork Yasmin Hurd is the Director MD/PhD Program, Professor in Psychiatry, Neuroscience and Pharmacology and Systems Therapeutics at the Friedman Brain Institute at the Icahn School of medicine. Dr. Matthew Smith has a Ph.D. in Social Work with Post-Doctoral Training in Psychiatric Epidemiology and Translational Neuroscience. His research interests cover the influence of alcohol and illicit substances on brain anatomy.

Science Talk
The Mind's Hidden Switches

Science Talk

Play Episode Listen Later Nov 22, 2011 28:19


Eric J. Nestler, director of the Friedman Brain Institute at the Mount Sinai Medical Center in New York City, talks about his article in the December issue of Scientific American magazine on epigenetics and human behavior, called "Hidden Switches in the Mind"