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Chemical probes are reshaping how we map GLP-1R in real time — revealing receptor pools antibodies can't reliably capture.This is Episode 2 of a 3-part GPCR tool-development series created in partnership with Celtarys Research.Summary:Dr. Johannes Broichhagen aka JB breaks down the design logic behind fluorophore-linked peptides, assay trade-offs, and what true receptor internalization looks like in live tissue. A concise masterclass in assay development and GPCR drug discovery.What you'll learn:• Why antibody variability pushed JB toward chemical probe engineering• The design logic behind Luxendin-based fluorescent tools — and how structure guides function • What “good assay development” looks like when cells, tissue, and probe behavior collide• Behind-the-scenes stories from the collaboration with David Hodson• Why parallelized experiments matter for reproducibility and signal quality• How small-molecule probes outperform antibodies in live-cell and tissue imaging• The surprising breakthroughs that shifted JB's entire research trajectory• Future directions: multi-color GPCR mapping, AI-guided ligand design, and in vivo chemical biology Dr GPCR Links & Resources:• Dr. GPCR Ecosystem: https://www.ecosystem.drgpcr.com/ • Membership & Pricing: https://www.ecosystem.drgpcr.com/university-pricing• Weekly News: https://www.ecosystem.drgpcr.com/gpcr-weekly-news
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Post Malone BioSnap a weekly updated Biography.Post Malone has had quite the eventful few days. Most recently, the Texas-born artist performed the halftime show at the Dallas Cowboys' Thanksgiving Day game against the Kansas City Chiefs, delivering what was described as an impressive performance. During the show, he paid heartfelt tribute to recently deceased former Cowboys player Marshawn Kneeland by wearing a pin with his number on his jacket. After the game wrapped up, Malone stayed behind for hours at AT&T Stadium, taking off his shoes to feel the turf barefoot while tossing a football around the empty field—a rare moment of leisure for someone of his stature.Off the field, Malone was spotted out shopping in Salt Lake City over the weekend with a mystery woman and two bodyguards at a local Trader Joe's. According to eyewitness reports, the couple was matching in hoodies, browsed the store for a while, and even shared a few kisses during their shopping trip. This sighting comes months after Malone's breakup with ex Christy Lee earlier this year, and notably, he was also spotted walking through Paris with an unidentified woman back in September.On the professional front, Malone is gearing up for a major milestone. He's set to headline his first-ever headline concert in India on December eighth in Guwahati, a significant moment for both the artist and India's live entertainment sector. The concert at Khanapara Veterinary College Ground is being organized by BookMyShow Live in partnership with the Government of Assam and is expected to draw considerable interest from audiences across the Northeast region.Malone also has additional tour dates lined up, including a performance scheduled for December fifth in Abu Dhabi at Etihad Park, followed by more shows in December and continuing into 2026.Away from the spotlight, Malone continues to prioritize fatherhood. His fourteen-month-old daughter has recently started running and taking steps, which the artist described as transformative for his perspective on life. He's mentioned that becoming a father has made him the happiest he's been in his entire life and has fundamentally changed how he approaches his career and personal wellbeing. According to interviews, his daughter loves his song Chemical and does a cute shoulder dance whenever she hears it.Get the best deals https://amzn.to/3ODvOtaThis content was created in partnership and with the help of Artificial Intelligence AI
A pool route looks peaceful from the curb, but the work sits where chemistry, electricity, plumbing, and customer trust collide. We brought on Sean Reardon, the insurance broker serving the United Pool Association, to unpack the real risks pool technicians face and why generic coverage so often misses the mark. From the UPA's origins as a mutual support network to the evolution of group policies built for technicians, we explore how smart coverage, good training, and honest reporting can turn worst-day scenarios into manageable claims.We walk through claim stories that stick. A heater installation near a shared wall led to alleged carbon monoxide poisoning when someone powered it up before venting was complete—an expensive reminder that pollution exclusions can swallow a “normal” pool tech job unless your policy is modified. A veteran pro mixed the wrong chemicals and triggered leaks across a skimmer line, proving that one rushed moment can mean weeks of remediation. A new hire “frisbeed” trichlor tabs into a dark-surfaced pool and branded it with round stains. And in a painful mix-up, chlorine meant for a dirty fountain ended up in a koi pond, wiping out prized fish within an hour.Sign up for UPA Insurance here:https://docs.google.com/forms/d/e/1FAIpQLSfRQjHJGFLIOqZVzHm4_PNUz8Tokl_InR0wjyp5ahO93h3Z0Q/viewform?usp=send_form• UPA's origin as chapters covering routes and sick leave• Why group insurance tailored to pool techs saves money and risk• Pollution exclusions and how endorsements change outcomes• Carbon monoxide claim and the importance of duty to defend• Chemical handling errors and skimmer line damage• Training gaps leading to “hockey puck” stains• Koi pond chlorination loss and rapid response• Cameras, transparency, and reporting incidents early• Practical habits to avoid co-mingling and mislabeling• How to join UPA and find the sign-up formThe easiest way to find the sign-up form for UPA is to go to my website, swimmingpoollearning.com. Again, that's swimmingpoollearnSend us a textSupport the Pool Guy Podcast Show Sponsors! HASA https://bit.ly/HASAThe Bottom Feeder. Save $100 with Code: DVB100https://store.thebottomfeeder.com/Try Skimmer FREE for 30 days:https://getskimmer.com/poolguy Get UPA Liability Insurance $64 a month! https://forms.gle/F9YoTWNQ8WnvT4QBAPool Guy Coaching: https://bit.ly/40wFE6y
How do footwear brands stay compliant in a world of ever-growing chemical regulations? In this episode of The Shoe-In Show, Matt Priest and Thomas Crockett welcome Eurofins experts Pratik Ichhaporia and Devender Singh to explore Prop 65, chemical testing, and the challenges of recycled materials. Learn how smart testing strategies, supply chain mapping, and proactive compliance help protect both consumers and brands. Learn more: https://www.eurofins.com With special guests: Pratik Ichhaporia, Vice President of Technical Services, Eurofins Consumer Products North America and Devender Singh, Global Innovations and Technical Director, Eurofins Hosted by: Matt Priest and Thomas Crockett
Chemical and biological attack attempts can be hard to detect, but that doesn't mean they aren't happening, including at major events and sports games, says Jeff Brodeur in this month's Security Management Highlights podcast, sponsored by Acoem. We look at other blind spots this episode, including in multitenant building security with René Reider, CPP, PSP, who explains how changing perspectives from flat, concentric circles of security to vertical strategies makes a difference for tenants. Then, Kim Pacelli outlines some of the frequently encountered challenges in discrimination and Title IX investigations and how security personnel can get involved. Additional Resources Learn more about this episode's sponsor, Acoem, and the ATD gunshot detection system here: https://acoematd.com/ Read more from Jeff Brodeur about chemical and biological weapon risk and screening in the latest issue of Security Technology: https://www.asisonline.org/security-management-magazine/monthly-issues/security-technology/archive/2025/december/essential-security-strategies-threat-of-chemical-attacks/ Dive deeper into screening skills and considerations here: https://www.asisonline.org/security-management-magazine/monthly-issues/security-technology/archive/2025/december/ Want to learn more about multitenant facility security and the challenges of porous facilities? Check out Security Management's coverage here: https://www.asisonline.org/security-management-magazine/articles/2025/11/multitenant/ If you're facing pushback on security controls, read this analysis here: https://www.asisonline.org/security-management-magazine/articles/2025/11/multitenant/canny-communication/ Before introducing new security measures, consider your change management process: https://www.asisonline.org/security-management-magazine/articles/2025/09/change-management/ Want to boost your creative, concierge-style security? You can learn from museums. https://www.asisonline.org/security-management-magazine/articles/2024/04/concierge/ What are your responsibilities during a Title IX investigation? Security personnel are often the first responders. Learn more in these Security Management articles: https://www.asisonline.org/security-management-magazine/articles/2025/11/title-ix-investigations/
A study of more than 1.3 million Americans found that people living in areas with high trichloroethylene (TCE) levels had a 10% greater risk of Parkinson's disease than those in cleaner regions TCE, a solvent once used in dry cleaning and degreasing, persists in air, soil, and groundwater for decades, exposing people through contaminated water and indoor air — even far from industrial sites Laboratory research revealed that TCE damages dopamine-producing neurons, disrupts mitochondrial energy production, and causes toxic protein buildup like that seen in Parkinson's patients The studies show that chronic, low-level exposure to environmental toxins silently erodes brain health over time, especially in older adults with weakened cellular repair systems Reducing exposure through clean water, good ventilation, and low-toxin household choices — while supporting your cells through restorative sleep, regular movement, and whole, unprocessed foods — helps protect mitochondrial energy production and strengthen long-term neurological resilience
Pool Pros text questions hereRudy dives headfirst into cyanuric acid — CYA, stabilizer, conditioner — the most misquoted, weaponized, and argued-about chemical in the pool industry. He breaks down what the science actually says about HOCl in stabilized water, why that old HOCl / OCl⁻ chart belongs in a museum, how CYA really impacts ORP, TA, and LSI, and why “chlorine lock” is less supernatural curse and more “you nuked the stabilizer and fed the biofilm.”Between the chemistry deep dive, Rudy hits the global pool-industry newswire: PHTA's APSP-11 rewrite, bromate and sodium bromide drama, media consolidation across major trade mags, massive international trade show attendance, European trends in energy-efficient builds, Australian code delays, and South American market movement. If you're running a pool business in 2025, this episode hits both your test kit and your bottom line.In This EpisodeCYA: Not the Villain, Not the Hero, Just Misunderstood Why cyanuric acid became “chlorine's sunscreen,” how chlorinated cyanurates actually work, and why CYA got popular in the first place — because it works, not because a committee was bored in the '60s.Why the Classic HOCl Chart is Garbage in Stabilized Pools Real HOCl Percentages at Common CYA Levels Copper Cyanurate Stains & “Prom Night Blue” Plaster CYA, Total Alkalinity & LSI: The Secret Sabotage ORP Suppression & Why Stabilized Pools Read “Low” Chlorine Lock is a Myth The Holy Sh*t Zone: CYA at 300 ppm and Up Alum Method to Lower CYA – How to Do It Right Fecal Incidents, CYA, and the Law (CDC Crypto Protocols) Does CYA Really Buffer pH? The Honest Answer Best-Practice CYA Targets Global Trade Magazine News RoundupRudy also runs through the week's biggest stories from around the world:PHTA's APSP-11 Water Quality Standard Rewrite Record Global Attendance at the 2025 PSP/Deck Expo in Vegas Pool & Spa News – Top 50 Service Survey AQUA Magazine's 50th Anniversary Preview Service Industry News – United Chemical Bromate Study Kenilworth Media's Big Acquisition Move EuroSpaPoolNews – Barcelona & Germany Specials SPLASH! Magazine – NCC 2025 Delay in Australia Brazil – Revista da Piscina & Pool Life Support the showThank you so much for listening! You can find us on social media: Facebook Instagram Tik Tok Email us: talkingpools@gmail.com
Oyster harvesting & sales resume in Franklin Harbour four months after being closed due to brevetoxin in the waters, South Australia's Varroa Industry Advisory Committee meets following multiple confirmed outbreaks of varroa mite, and the APVMA again delays its decision on the future use of paraquat and diquat in Australia.
Does your sciatica seem to vanish for a few days, giving you hope that you are finally "fixed," only to return with a vengeance the moment you try to resume your normal life? This cycle of relief followed by relapse is incredibly common and deeply frustrating. In this session, we explain the critical difference between symptom relief (the absence of pain) and structural healing (the repair of the tissue). Understanding this distinction is the key to breaking the cycle of recurring back pain and preventing future flare-ups.Using the analogy of a grazed eyelid, we explore a vital concept: just because you can see perfectly clearly (function is 100%), it doesn't mean the wound on your eyelid has healed (structure is still damaged). In the same way, your back can often move pain-free while the disc is still fragile. We discuss the "Scab Phase"—that dangerous window where you feel capable but are clinically vulnerable. Learn why "testing" your back during this phase is exactly like picking a scab, and how to navigate this timeline safely to build true, long-term spinal resilience.
Just in time for holiday travel, a snow storm impacting much of Minnesota has left several inches of snow in a swath from southwestern Minnesota to the northeast. Roads were slick and snow covered Wednesday morning. I-94 was closed for a time due to jack-knifed semis. The Minneapolis-St. Paul International Airport says Wednesday is one of the busiest travel days of the year.Federal authorities on Wednesday took at least two people into custody in St. Paul during an operation that drew protesters. St. Paul Police confirmed their officers used chemical irritants. Police chief Axel Henry says his department did not violate the city ordinance that prevents it from assisting with federal enforcement. Police officers used chemical irritants and less lethal projectiles on protesters and the press. MPR News photojournalist Kerem Yucel was hit by the chemical irritants.Best Buy is reporting a strong third quarter in its latest earnings report — and the company also is raising its sales and profit forecasts for the year. The Richfield-based electronics retailer says comparable-store sales rose nearly 3 percent in the last quarter — its biggest gain in three years.As Minnesotans get ready for a holiday that revolves around a large meal, people who work in hunger relief are asking people to remember food shelves and those in need. A family from the Red Lake Nation will represent three generations in the Macy's Thanksgiving Day Parade in New York this year.
Discover how Citroniq is transforming ethanol into bio-polypropylene through its E₂O process, driving sustainable plastics innovation. In this first episode, Kelly Knopp, CEO and Co-founder of Citroniq, shares how the company is transforming ethanol into bio-polypropylene through its innovative E₂O process. Listen to learn: Citroniq's approach to bio-based polypropylene How scale and technology choices influence commercial viability Why bio-polypropylene stands out among plastics for sustainability impact Click here to find out more about Argus' Biochemicals, a new service offering references for bio-ethylene, bio-propylene, bio-butadiene, and bio-benzene.
A widely used grease remover and dry-cleaning chemical called tetrachloroethylene (PCE) has been linked to liver fibrosis, a condition that causes scarring and loss of liver function even in people who don't drink alcohol or have obesity Researchers found that people with measurable levels of PCE in their blood were three times more likely to have liver fibrosis, and for every tiny one-nanogram-per-milliliter increase in PCE, the risk increased fivefold PCE exposure often occurs through inhaling fumes from dry-cleaned clothes, contaminated air, or drinking water, and the chemical can also enter through the skin, affecting the liver, kidneys, heart, and nervous system Long-term exposure to PCE has been linked not only to liver disease but also to nerve damage, reproductive issues, and several cancers, including those of the bladder and liver, prompting the EPA to begin phasing it out Lower your risk of liver damage by switching to solvent-free wet cleaning, letting dry-cleaned clothes air out before use, replacing household products that contain PCE, and supporting liver repair through clean nutrition, hydration, and sun exposure
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Can natural herbs aid recovery from anorexia? What an analysis of Hitler's DNA tells us about how genes shaped his personality; Can surgical anesthesia accelerate memory loss? Bananas could be interfering with your smoothie's health benefits; Not just sun, but pesticides and herbicides increase risk for melanoma; Chemical residues on produce impair male fertility; Proliferation of fast-paced social media videos are dumbing us down; Doctors aren't less resilient, the demands of medicine are just fostering unprecedented levels of physician burnout.
It's currently thought that around one billion people worldwide aren't getting enough protein to meet their daily needs. Alongside this, it's becoming increasingly clear that the large-scale farming of livestock and the overfishing of the Earth's oceans to provide us with vital sources of protein are causing great harm to the environment. But could the production of more alternative protein sources, such as cultivated meat, plants like algae and duckweed and even insects, help provide us with a neat solution to both of these issues? As part of our four-part miniseries, Future of Food, we're joined by a panel of three researchers based at The University of Sheffield: Professor of biomanufacturing Tuck Seng Wong, Professor of plant cell signalling Julie Gray and a Senior Lecturer based at the School of Chemical, Materials and Biological Engineering, Dr Kang Lan Tee. They tell us about the latest technological developments that are helping us to produce healthy, nutritious proteins in novel ways, how many of these methods can make much more efficient use of resources such as energy and water, and why perhaps many of us could benefit from being a little more open-minded when it comes to thinking about what we put on our plates. Learn more about your ad choices. Visit podcastchoices.com/adchoices
Women in Chemical's interviews, Roseanna Bennett, Business Manager at Harcros for Woman of the Week 11/24/2025.
Check out Sam Tripoli's new comic book "Chaos Twins!" 2nd issue is about to drop!Visit www.chaostwins.com to support Sam's family-friendly project!Check out Sam Tripoli's 3rd Crowd Work Special "Barbecued: Live From Kansas City" Sept 20th on Youtube.com/SamTripoliComedyWatch Sam's comedy special here: www.youtube.com/samtripoliPlease check out Sam Tripoli's Linktree: https://linktr.ee/samtripoliPlease check out Midnight Mike's Internet:The OBDM Podcast Website: https://ourbigdumbmouth.com/Twitter: https://x.com/obdmpodCheck out the Naked Gardener's Band:The 3rd Pyramid Band - Topichttps://bit.ly/4fpNMMr1. Professor's 9/11 breakdown of coincidences ft larry silverstein - @truth.in.media2. Mary poppins & pennywise reddit theory about connecting with children- @rizhaiderrr3. Mysterious Caucasian & Arminian region - @conceptsinfluential4. Great wall of China kept stuff in or out ? @shaynevibes_truth5. Patterns in nature lead back to sr francis bacon- @acidforsquares6. Unclean spirits have shown to be territorial when humans practice transcendentalmediation -@blurrycreatures7. Couple splits eggs by initials - n/a8. College honeypotter - @theshotclock9. Car crash or explosives planted in car that caused crash - @christgnosisig10. Old Testament is based on pure astrology & zodiac - @igorkryan11. Retired US intelligence officer details Admiral Byrd's journey to inner earth-@nightgod33312. The reason why cats eyes are similar to reptiles -@unanswered_universe13. Video of day, woke toys - @obdm14. Taylor swift & Jeffery Dahmer are ninth cousins -@peggybolton_215. Preflood incest archaeology - @gillyanstone16. Mk ultra never ended -@omgthewhyfiles17. Asking AI to make recalled toys pt 1 - @obdm18. Action Andrew Jackson beat his attempted assassin - @benjamin.sloutsky19. Chemical breakdown of cloud seeding - @tuckercalson20. 8 predictions for the world -@truthseeker0101121. Blistered mating beast monkeys -@zeke.darwinscience22. Josiah getting scalped -@chettripper23. 666 architect -@shaynevibes_truth24. Dark truth about Alice in Wonderland -@kryptobandit225. Egyptian pharaoh blacklisted -@aslanpahari26. Peter Nygard harvesting adrenochrome -@atruthforyou27. “Im okay, im doing great” affirmation -@wearethedreameaters28. MLKangz taken out with a pillow -@tfu.podcast29. Trans-tracker -@aranisagoodboy30. Legal fraud & seasoning the money -@keisenhewer31. Clever money laundering with charities -@moneyplixmediaco32. Caterpillar to butterfly chemical breakdown -@explainerfilms Learn more about your ad choices. Visit podcastchoices.com/adchoices
A screencast from Chapter 7a in CH 221 entitled “Balancing Chemical Equations”
“The best ideas in drug discovery were often blocked not by biology, but by synthesis,” Boiko told TechCrunch. Synthesis is the creation of new molecules by using chemical reactions. It's like a recipe or Lego pieces, where small pieces, ingredients, molecules, come together to form a wider puzzle picture, a food dish, a larger molecule. Learn more about your ad choices. Visit podcastchoices.com/adchoices
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Contaminated Site Clean-Up Information (CLU-IN): Internet Seminar Audio Archives
In 2023, ITRC published the Sediment Cap Chemical Isolation Guidance to supplement the 2014 Contaminated Sediments Remediation Guidance with the goal of improving consistency in sediment cap performance outcomes. Sediment capping is a commonly selected remediation approach and numerous designs have been completed. Previous cap designs have been evaluated in multiple ways, and these varying approaches have led to some differences in selection of chemical design criteria, construction tolerance specifications, and monitoring/maintenance objectives for sites with similar characteristics and contaminants, leading to different expectations for long-term performance and reliability. The ITRC Sediment Cap Chemical Isolation Guidance provides a framework for the design, construction, and long-term monitoring of the chemical isolation function of sediment caps. The framework consists of an iterative design process informed by site-specific data that balances achievement of chemical design criteria, physical design constraints, constructability and permitting requirements. In addition, the guidance summarizes key construction considerations and presents a recommended approach for monitoring and evaluating long-term chemical isolation performance. The recommended framework presented in the Sediment Cap Chemical Isolation Guidance is illustrated below. The Sediment Cap Chemical Isolation Training will cover several key elements of the recommended framework, including: A capping overview that summarizes objectives of capping, role of the chemical isolation layer, and generic cap types and compositions. A discussion of performance objectives and design concepts that includes the selection of chemical isolation performance targets criteria and development of design criteria while considering the site setting and conceptual site model elements. An overview of chemical isolation layer modeling tools and discussion of their applicability to support chemical isolation design, important model input parameters, and the impact of uncertainty and sensitivity of modeling results. A summary of chemical isolation construction considerations, including an overview of available construction methods and tolerances and quality assurance and quality control measures. A discussion of cap performance monitoring and maintenance objectives and approaches that include developing monitoring objectives to assess chemical isolation performance and methods for guiding long-term maintenance decisions. We encourage participants to review the ITRC Sediment Cap Chemical Isolation Guidance (SD-1) before and after the training to become familiar with the topics and recommendations discussed during the training. This training is intended for all environmental professionals working in the field of sediment capping projects, including regulators and other government agency staff, consultants, project stakeholders, and industry. To view this archive online or download the slides associated with this seminar, please visit http://www.clu-in.org/conf/itrc/sd-1_111825/
To explore more on Biohacking & Longevity: https://programs.sajeevnair.comTo know more about EPLIMO program using Genetic Testing: https://www.myeplimo.com/masterclassGuest Suggestion Form: https://forms.gle/bnaeY3FpoFU9ZjA47Disclaimer: This video is intended solely for educational purposes and opinions shared by the guest are his personal views. We do not intent to defame or harm any person/ brand/ product/ country/ profession mentioned in the video. Our goal is to provide information to help audience make informed choices. The media used in this video are solely for informational purposes and belongs to their respective owners.Order 'Build, Don't Talk' (in English) here: https://amzn.eu/d/eCfijRuOrder 'Build Don't Talk' (in Hindi) here: https://amzn.eu/d/4wZISO0Follow Our Whatsapp Channel: https://www.whatsapp.com/channel/0029VaokF5x0bIdi3Qn9ef2JSubscribe To Our Other YouTube Channels:-https://www.youtube.com/@rajshamaniclipshttps://www.youtube.com/@RajShamani.Shorts
In Episode 274 of the Pool Nation Podcast, Edgar and Zac kick off a new business series by tackling the topic most pool pros feel every day but rarely talk about openly: pricing—and how to build real profit into every single service you offer. Fresh off the Pool Nation Conference, the guys recap the buzz around the $10,000 Pool Pro Challenge, shout out this year's Pool Guy/Girl of the Year and Rookie of the Year winners, and then jump straight into the financial reality of 2025: Equipment prices up 7–9% Chemical costs climbing Insurance and utilities spiking Labor and drive time more expensive than ever Edgar and Zac break down why most pool pros fall behind financially, why so many avoid raising prices until it's almost too late, and how chasing revenue (more pools, more work) instead of margin (profit per pool) keeps you stuck in the grind. Then they dive into the foundation of your financial health: knowing your true cost-per-pool. They walk through: What really belongs in your cost-per-pool Why your “$20 cost” is probably actually $60+ How drive time, callbacks, office labor, and insurance destroy profit when you ignore them The danger of relying only on apps for chemical costs without looking at what actually leaves your bank account This is Part 1 of a multi-episode series on Pricing Power: Building Profit Into Every Service. By the end of this episode, you'll see why you need to know your numbers. In the next episodes, they'll show you how to calculate your cost-per-pool in five minutes, build in margin, raise prices confidently, and keep more of your customers. If you've ever looked at your account balance and thought, “Why am I working seven days a week and still feel broke?” …this episode is for you. ⏱️ Episode Chapters / Timestamps [00:00:00] Intro – Pool Nation Podcast opening & show welcome [00:01:00] Edgar sets the stage – Today's topic: pricing & building profit into every service [00:02:00] Zac on “slow season” that isn't really slow – using this time to dig into the back end of the business [00:03:00] Post-conference recap – Pool Nation Conference, Awards, $10K Pool Pro Challenge & winners [00:06:00] The reality of 2025 – builders slowing, costs rising everywhere, and what that means for service companies [00:07:00] Equipment price increases – Pentair, Hayward, Jandy and what those jumps mean for your margins [00:09:00] Everything is up – chemicals, supplies, test kits, office supplies, utilities, and why it all creeps up unnoticed [00:11:00] The “loss leader” trap – why weekly maintenance should NOT just be a way to get repairs [00:12:00] Treating each vertical as a micro-business – service, filters, startups, repairs all need to be profitable [00:14:00] Why most pool pros fall behind financially – running on revenue instead of margin [00:16:00] The “busy but broke” problem – working 7 days a week and still not seeing the profit [00:18:00] The power of knowing your numbers – the “aha” moment when techs finally see their true cost [00:19:00] Why pros avoid raising prices – fear of confrontation, customer pushback, and delaying until it's too late [00:21:00] Reality check – your costs don't wait just because you're uncomfortable raising rates [00:23:00] Confidence through clarity – how cost-per-pool gives you certainty in your pricing decisions [00:27:00] What is cost-per-pool really? – total cost vs gross profit and why both matter [00:31:00] Breaking down cost-per-pool – chemicals, labor, payroll tax, workers comp, admin labor, gas & more [00:34:00] Drive time & hidden minutes – the silent profit killer nobody tracks [00:37:00] Vehicle wear and tear – tires, oil changes, brakes and why they belong in your cost [00:38:00] Insurance creep – auto, GL, workers comp and why they keep climbing [00:40:00] Replacing equipment & office gear – computers, printers and where that money really comes from [00:42:00] Scenario math – why your “$30 stop” might only be making you $5–$6 [00:45:00] Hidden leaks – algae treatments, extra time on site, “little favors” and non-billable work [00:48:00] Growth reality – what you can do as a one-poler that breaks you once you have a team [00:51:00] The four phases of business – why what worked at 40 pools won't work at 200 [00:55:00] App data vs real-world costs – what your app tracks (and what it completely misses) [00:59:00] Edgar's warning – don't get lost in 300 individual pools, start with total cost-per-pool [01:01:00] What's coming in Part 2 – 5-Minute Cost Calculator, margins, price increases & customer retention [01:02:00] Final thoughts – foundational principle: financial wellbeing of pool pros & “know your numbers”
276: Recently, the EPA announced some major rollbacks on chemical regulations, and I am NOT happy about it. I'm breaking down the latest changes and explaining why I'm angry - but not surprised - at how things are going. This is more than just a right or left issue - if we don't stop these chemicals at the source, everybody loses. Topics Discussed: → What are PFAs and why are they dangerous? → How are PFAs contaminating our food and water supply? → What did the recent EPA regulations change? → Why are TSCA rollbacks a problem for public health? → How can we take action to reduce chemical exposure? Timestamps: → 00:00 - Introduction → 01:19 - PFAs Regulations → 05:18 - A Problem Across the Aisle → 11:07 - TSCA Rollbacks + Speaking Out Check Out Courtney: → LEAVE US A VOICE MESSAGE → Check Out My new FREE Grocery Guide! → @realfoodology → www.realfoodology.com → My Immune Supplement by 2x4 → Air Dr Air Purifier → AquaTru Water Filter → EWG Tap Water Database Produced By: Drake Peterson
Plus, the EU launches antitrust probe into how Google's anti-spam policy affects publishers' search rankings. Learn more about your ad choices. Visit podcastchoices.com/adchoices
You know what's passé? Chemical rockets. Powering a space ship by harnessing the expanding gasses of a controlled explosion and shooting off to parts unknown guided only by fire, math, and spite for the force of gravity? Yawn. What if instead you got like, 40 cyclists with thighs as big as tree trunks that just won't quit, stuck them on some stationary bikes, and used them to power your spaceship like it was a sci-fi trireme from the year 30,000? WOULD THAT SOLVE ANYTHING??? Trace is going to find out.Meanwhile Julian is very concerned with the structural integrity of some fairy-tale pig houses, because they aren't up to code and there's a storm a-comin'. And that storm's name is Wolf. Big Wolf. Big Bad Wolf.QUESTIONS THIS WEEKJulian: "How much wind and energy was the big bad wolf able to generate in the three little pigs?" from AdamTrace: "What's the most efficient way to extract energy from a human?" from LudvigDo you have an absurd question? Maybe it's a silly idea that popped into your head, a shower thought about the nature of reality, or a ridiculous musing about your favorite food? Whatever your question, we want to answer it—tell us!HOW TO ASK A QUESTION
Chemical regulations are only part of the story. In our latest episode, Bob Trimble, Program Manager for Global Restricted Substances at Intertek Assuris, sits down with Anju, an expert in U.S. consumer product safety, to explore how CPSC e-filing is changing the compliance landscape, specifically for children's products.From documentation requirements to digital reporting, they unpack the challenges companies face and share insights to help you stay ahead of evolving safety expectations.Tune in to learn how to simplify compliance and protect your brand's reputation in a more transparent, data-driven future.Speakers:Robert Trimble, Program Manager – Global Restricted Substances, Intertek AssurisAnju Kang, Consultant – Risk Strategy & Management, Intertek Assuris Follow us on- Intertek's Assurance In Action || Twitter || LinkedIn.
Rural news and events from Tasmania and the nation.
In this episode, we interview Eduardo Alegria, Global Business Director for Metal Packaging Inks at Sun Chemical. They discuss Sun Chemical's new metal packaging colour library, developed with X-Rite, which aims to standardise colour communication and streamline production. Eduardo shares insights on the evolution and resilience of the metal packaging sector, digital printing innovations, and sustainability efforts, including bio-renewable inks and waste reduction.The conversation also covers industry challenges, consumer trends, and the importance of clear messaging around metal packaging's sustainability advantages.
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Visit: RadioLawTalk.com for information & full episodes! Follow us on Facebook: bit.ly/RLTFacebook Follow us on Twitter: bit.ly/RLTTwitter Follow us on Instagram: bit.ly/RLTInstagram Subscribe to our YouTube channel: www.youtube.com/channel/UC3Owf1BEB-klmtD_92-uqzg Your Radio Law Talk hosts are exceptional attorneys and love what they do! They take breaks from their day jobs and make time for Radio Law Talk so that the rest of the country can enjoy the law like they do. Follow Radio Law Talk on Youtube, Facebook, Twitter & Instagram!
Women in Chemical's interviews, Julie Roberts, President, Director, Supplier Growth at Chempoint for Woman of the Week 11/10/2025.
Piero San Giorgio is one of Switzerland's best selling authors. After 20 years as an executive in the software business, Piero decided to write essays about the future. His first book Survive —The Economic Collapse was in the top-50 best selling books of 2012 in France and has sold over 200,000 copies, with translations into English, Italian, Russian, Arabic, Romanian, Polish, Turkish etc. and has a foreword by JHKunstler. His other books are , CBRN (How to Survive Nuclear, Radiological, Biological,and Chemical events), and Giuseppe: A Survival Story, a biographical novel about his grandfather's ordeals in WW2. The KunstlerCast theme music is the beautiful Two Rivers Waltz written and performed by Larry Unger
“…and today we're talking about a starfish that the jester stole. But more on that later.” Dive into the dazzling depths of the ocean, where a spiky sovereign slinks silently across coral castles, whispering secrets through an invisible ink of proteins. This prickly predator, a veritable porcupine of the sea, rules the reefs with a […]
In 1865, German physician and medical writer Justus Hecker published a volume titled The Epidemics of the Middle Ages. In a footnote, he remarked on a strange phenomenon: an outbreak of meowing nuns. In this minisode, I bring you the story of the meowing nuns of late medieval France and the men who told their story.Researched, written, and produced by Corinne Wieben with original music by Purple Planet.SourcesPrimaryAristotle. History of Animals. Translated by d' A. W. Thompson. In Aristotle, Complete Works. Vol. 1, 774–993. Princeton, NJ: Princeton University Press, 1984.Aristotle. Politics. Translated by Ernest Barker. Oxford: Oxford University Press, 1977.Hecker, J. F. C. The Epidemics of the Middle Ages. Translated by B. G. Babington. London: Woodfall, 1844. Zimmerman, J. G. Solitude. Vol. II. London: Dilly, 1798.SecondaryBartholomew, Robert E. Little Green Men, Meowing Nuns and Head-Hunting Panics: A Study of Mass Psychogenic Illness and Social Delusion. London: McFarland, 2001.Bartholomew, Robert E. and Simon Wessely. “Protean Nature of Mass Sociogenic Illness: From Possessed Nuns to Chemical and Biological Terrorism Fears.” British Journal of Psychiatry 180, no. 4 (2002): 300–306.Mercer, Christia. “The Philosophical Roots of Western Misogyny.” Philosophical Topics 46, no. 2 (2018): 183–208.Penso G. Roman Medicine. 3rd ed. Noceto: Essebiemme, 2002.Tasca, Cecilia et al. “Women and Hysteria in the History of Mental Health.” Clinical Practice and Epidemiology in Mental Health 8 (2012): 110-9.Support the showEnchantedPodcast.netBluesky/enchantedpodcast.net
Parents!Listen to this podcast, audiobooks and more on Storybutton, without your kids needing to use a screened device or your phone. Listen with no fees or subscriptions.—> Order Storybutton Today The Spy Starter Pack
Chemical engineering senior Addison Faggard, fundraising chair for the Auburn chapter of Engineers Without Borders, is making a difference in the world. And the people of Quesimpuco finally have the pictures to prove it.
This week I had the pleasure of speaking with Greg Gartland, Chief Executive Officer of 3E. We discuss 3E's business offerings, how it defines its place in the very competitive world of chemical information management, the role artificial intelligence has in this space, and trends Greg sees driving growth in chemicals, product stewardship, and sustainability. ALL MATERIALS IN THIS PODCAST ARE PROVIDED SOLELY FOR INFORMATIONAL AND ENTERTAINMENT PURPOSES. THE MATERIALS ARE NOT INTENDED TO CONSTITUTE LEGAL ADVICE OR THE PROVISION OF LEGAL SERVICES. ALL LEGAL QUESTIONS SHOULD BE ANSWERED DIRECTLY BY A LICENSED ATTORNEY PRACTICING IN THE APPLICABLE AREA OF LAW. ©2025 Bergeson & Campbell, P.C. All Rights Reserved
The Habitability of Venus's Clouds: Following Chemical Clues to Possible Life. Dr. David Grinspoon (Planetary Science Institute) and Dr. David Livingston (The Space Show) discuss the growing mainstream focus on the potential for life in the clouds of Venus. Although the surface is too extreme, the cloud layer provides a relatively benign environment with low pressure and cool temperatures, prompting questions about potential habitability. Life might have migrated to the clouds if Venus lost its ancient, biologically promising oceans. The controversial detection of phosphine, a chemical largely produced by life on Earth, serves as an intriguing, strange chemical clue suggesting something "weird" is happening. Grinspoon also addresses panspermia, noting that hardy organisms like tardigrades could potentially survive natural transfers between planets or even interstellar journeys. The ideal altitude, or "sweet spot," for possible life is around 50 kilometers, where conditions resemble Earth's surface.
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Chemical reactions are the backbone of modern society: the energy we use, the medicines we take, our housing materials, even the foods we eat, are created by reacting different substances together. If we zoom in, it's the atoms within these substances that rearrange themselves to give rise to new substances with the properties we need.However, chemical reactions are far from perfect. They're often inefficient and their waste products can be harmful to the environment. Getting to grips with what goes on at the scale of individual atoms has long been a sticking point.Dame Pratibha Gai has spent much of her career pioneering novel microscopes to bring this seemingly inaccessible atomic world into sharp focus. Now Emeritus Professor of Chemistry at York University, her microscope, known as the environmental transmission electron microscope, is housed in labs around the world. It allows scientists, like herself, to observe chemical reactions in real-time, in exquisite atomic detail, and tinker with them to create products that are not only better for all of us, but also the environment.Presented by Jim Al-Khalili Produced by Beth Eastwood Revised for World Service by Minnie Harrop
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Bob is the created and owner of Trade Genius Academy. Bob also does a podcast on YouTube which is called Trade Genius. Germany's industrial backbone is buckling under the weight of soaring energy costs and a protracted manufacturing slump, exacerbating the nation's economic woes as factories shutter and jobs flee to cheaper shores. Chemical producers, for instance, cite skyrocketing energy expenses as the primary culprit for relocating operations to China, where costs are far more predictable and affordable, leaving behind a trail of idle plants and lost competitiveness in Europe. This comes amid the latest HCOB Manufacturing PMI reading of 49.6 for October, a marginal uptick from September but still firmly in contraction territory below the 50 threshold, signaling persistent output declines, weakened new orders, and employment cuts across key sectors like autos and machinery. With household energy bills already among the world's highest—rivaling those in Ireland and Italy—Berlin's green energy pivot and nuclear phase-out have only amplified the pain, turning what was once Europe's manufacturing powerhouse into a cautionary tale of policy missteps fueling deindustrialization. Meanwhile, amid this fiat-fueled turmoil, gold and Bitcoin are surging to unprecedented peaks, underscoring a global flight to hard assets as trust in central banks erodes. Bitcoin shattered its prior record, climbing above $109,000 while gold and silver notched fresh all-time highs, drawing parallels to Satoshi Nakamoto's visionary "Bit Gold" precursor that blended digital scarcity with precious metal reliability. This rally coincides with mounting calls to dismantle the Federal Reserve entirely, viewing it as the root of endless debt spirals and inflationary theft—proponents argue abolishing the central bank, ending its unconstitutional money-printing monopoly, and returning to sound money backed by gold or competing currencies would restore fiscal sanity and curb the very imbalances driving these asset booms. As the Fed signals an end to quantitative tightening in December, whispers of outright elimination gain traction in liberty-minded circles, positioning crypto and bullion not as speculations, but as bulwarks against a system teetering on collapse.
As federal agents continue to do immigration enforcement across the Chicago area, they frequently deploy chemical munitions like tear gas and smoke bombs on protesters. What's inside these weapons? What are their health effects or environmental impacts? In the Loop hears from Dr. Monica Peek, physician and health disparities researcher and a national board member of Physicians for Human Rights and from Oscar Sanchez, co-executive director, Southeast Environmental Task Force. For a full archive of In the Loop interviews, head over to wbez.org/intheloop.
Welcome to episode 267 of Growers Daily! We cover: finding good mulches, the (somewhat false) productivity of conventional agriculture, and the changing landscape of farming information. We are a Non-Profit!
BofA Securities analyst Matthew DeYoe discusses his industry's challenges and why bargain hunters should stay “downstream” for now. Learn more about your ad choices. Visit megaphone.fm/adchoices
Former DEA Administrator Derek Maltz joins Dr. Phil McGraw to expose the China–Mexico pipeline flooding America with synthetic opioids, the next generation of killers beyond fentanyl. Learn how you can protect your family and become part of the solution. Subscribe now for more deep-dive conversations with Dr. Phil on crime, policy, and the fight for America's future. The Dr. Phil Podcast | Subscribe | Rate | Share: YouTube: bit.ly/3h3lj8n Apple Podcasts: apple.co/3w76ihw Spotify: spoti.fi/44ihdwv Website: drphilpodcasts.com