Podcasts about MSC

Only roughly 50% of new GLP-1 prescriptions were getting approved for coverage in 2023. From a plan sponsor's seat, that looks like pharmacy trend spiking 9%, 12%, even 20% year over year. From a pharma manufacturer's seat, it's half their prescriptions not getting filled. Same market, opposite problems — and that's exactly the lens this episode flips on. In this episode, Stacey Richter speaks with Ophelia Johnson, who built new business channels for a pharmaceutical manufacturer that created the GLP-1 boom and has since launched a consulting practice at e-fi.works, about how cash pay models work from the inside — coupon platforms, telehealth channels, white label pharmacy models, and employer carve-outs — and where the new fees are hiding. WHAT YOU'LL LEARN ✅ How the Inflation Reduction Act, PBM legal scrutiny, drug shortages, and the compounding bypass converged with ~50% GLP-1 prior auth denial rates in 2023 to push pharma into building cash pay channels that cut the PBM out entirely ✅ How the savings coupon model works: manufacturer buys the patient down to a flat transparent cash price via platforms like GoodRx, pays a fixed per-script fee instead of a PBM rebate, and the coupon platform makes the pharmacy whole — transparent math, no black box ✅ How the telehealth channel and white label pharmacy models extend the distribution chain beyond retail — and why shipping costs, credit card fees, dispensing fees, and new supply chain partners create gross-to-net and revenue leakage risk for manufacturers not built for it ✅ Why "direct to employer" is a misnomer: PBM contracts prohibit pharma from selling directly to self-insured employers, so third-party transparent administrators have emerged — but plan sponsors need to run the math first, given ERISA complications and PBM contract leverage ✅ How PBMs are now charging fees for hub-like patient support services to manage the exact prior auth complexity they created — a Whack-a-Mole shift of profitability that everyone needs to map before signing anything ✅ Ophelia's three-part practical advice: map the full patient journey and all ecosystem player incentives before building any new model (pharma); treat affordability as a clinical risk factor (clinicians); demand auditable medication abandonment data rather than settling for rebate yield metrics (plan sponsors) WHY THIS MATTERS If collaboration is the next innovation, everyone has to understand the incentives of every player in the ecosystem — not just their own. The same 50% of unfilled GLP-1 prescriptions that looks like runaway pharmacy trend from a plan sponsor's seat looks, from a manufacturer's seat, like half their market going dark — and both sides are making moves that affect each other. Understanding those moves, where fees are being layered on, and when fair profit tips into what Stacey calls profiteering is what this episode maps. TUNE IN NEXT WEEK Next week is the 401-level companion to this one — Stacey goes solo on the PBM and GPO contracting mechanics behind why cash pay became a thing, and why cheaper or better drugs can inexplicably end up off formulary or buried under prior auth. === LINKS ===

Join our World Cup YouTube coverage on MSC TV below: https://www.youtube.com/@ModernSoccerCoachTV What tactical themes are emerging from the opening week of World Cup 2026? In this episode of the Modern Soccer Coach Podcast, Gary Curneen shares three coaching lessons that have stood out so far from the tournament. Drawing on reports from the MSC analysis team and observations from matches across the competition, we explore why the mid-block is becoming the defensive strategy of choice, how the best teams are finding multiple solutions to break it down, and why in-game adaptation may be the most important coaching skill in tournament football. Featuring examples from Brazil, Morocco, the Netherlands, Japan, Australia, and more, this episode is packed with practical insights for coaches looking to improve their understanding of both attacking and defending at the highest level. ⚽ Why the mid-block is defining the tournament ⚽ Different ways teams are defending without the ball ⚽ How top teams create new attacking solutions when Plan A stops working ⚽ The importance of tactical adaptation during games ⚽ Key coaching takeaways from the opening matches Watch our daily World Cup tactical breakdowns on MSC TV and join the conversation as the tournament unfolds.

Why do so many adults with ADHD struggle with alcohol, even when they know it's not helping them? In this episode, Lynne Edris talks with Colleen Freeland about the powerful connection between ADHD, dopamine, nervous system regulation, and alcohol use. They explore: • Why ADHD brains often seek relief through alcohol and other coping behaviors • The difference between drinking for pleasure and drinking for relief • How dopamine and urgency drive unhealthy patterns • Why shame keeps us stuck • How to build healthier responses to stress and overwhelm • The mindset shift that makes lasting change possible Whether alcohol is your challenge—or whether your coping mechanism looks more like procrastination, scrolling, shopping, or overworking—this conversation will help you better understand your brain and create change with more compassion and less self-judgment. Colleen Freeland is an Intuitive Drinking Coach and host of the globally top-ranked It's Not About the Alcohol podcast. Colleen founded Emotional Sobriety Coaching© for high achieving professional women who want to reduce alcohol consumption by 80 percent. She combines holistic and evidence-based strategies in Neurophysiology, Cognitive Reframing, and Spirituality to reprogram the mind and body - so you actually prefer drinking in moderation. Colleen secretly struggled with Alcohol Use Disorder for over 20 years before discovering that the solution to overdrinking is to get happy, not sober. She is an Addiction and Recovery-Certified Master Life Coach with an MSc in Health Coaching, a BS in Biology and Chemistry Education, and is certified as a Women's Functional and Integrative Health Professional. Learn more about Colleen at https://www.emotionalsobrietycoaching.com/ Podcast Co-Host Lynne Edris s a Productivity & ADHD Coach who helps distracted professionals from all over the world learn to accomplish what they intend and take control of their days with ease so that they can perform at the level of their abilities and have more time, more energy and more bandwidth for what matters most to them. Lynne is a woman, wife, and mom with ADHD herself, so she understands the struggles and challenges of living with ADHD. She has gone from living in the constant state of chaos, overwhelm, and under-performance that adults with ADHD know far too well, to living a life of more success and fulfillment than she once dreamed possible. Her passion is to help others fulfill their own potential and start "firing on all cylinders" in all areas of your life. You can learn more about Lynne at www.CoachingADDvantages.com, and visit www.ProductivityBreakthroughQuiz.com to take her complimentary self-assessment! RESOURCES & LINKS Take Lynne's Productivity Breakthrough Quiz: https://www.productivitybreakthroughquiz.com Learn more about Lynne Edris: https://www.coachingadvantages.com Learn more about Colleen Freeland at https://www.emotionalsobrietycoaching.com/ Join the ADHD Support Talk Facebook Community: https://www.facebook.com/groups/adhdsupporttalk We'd love to hear from you! ADHD Support Talk Radio is an award winning Podcast for Adults with ADD / ADHD. Co-hosts Tara McGillicuddy and Lynne Edris are joined by Adult ADHD experts and they cover important topics related to Adult ADD / ADHD. Podcast guests include Dr. Edward Hallowell, Dr. Stephanie Sarkis, Dr. Ari Tuckman, Laurie Dupar, Terry Matlen and many more. Tara McGillicuddy is the Producer, Owner and Co-host of the ADHD Support Talk Radio Podcast. You may contact Tara with general questions or feedback about the podcast, Lynne Edris is the Co-host of the ADHD Support Talk Radio Podcast. You may contact Lynne with feedback about her episodes or if you are interested in having her interview you as a guest. https://adhdsupporttalk.com/about-podcast/ We may be an affiliate for products we mention or recommend. If you purchase those items through our links, we may earn a commission.

Pronation can be misunderstood as a scary, dangerous risk for injury - and people use that to sell you something. In reality, a certain degree of pronation is a normal part of the running gait. However, excessive or limited pronation can be problematic for some runners. So how do you know if you need to worry about overpronation or buy stability shoes? In episode 171, we take an evidence-based approach and guide you through anatomy and recent research surrounding pronation. Thank you to our sponsors:✨ Good Ranchers: American-grown meat, delivered frozen to your doorstep. Use code IRON for $40 off the first order, or $100 off across the first three orders when customers start a subscription. Plus free protein with every order (choice of burgers, bacon, or chicken breasts). Be sure to mention “Tread Lightly Podcast” for how you heard about the company! https://www.goodranchers.com/In this episode, you'll learn:✅ Why pronation is a normal part of a healthy running gait✅ If stability shoes are appropriate for you or not✅ Whether pronation causes an injury or is a symptom of an injury✅ Should you change your running gait?✅ The difference between overstriding and heel striking✅ Should you increase your running cadence?If You Enjoyed this Episode, You May Like:

Editor's Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief, Linda Brubaker, MD, Deputy Editor, and Christopher W. Seymour, MD, MSc, Associate Editor of JAMA, the Journal of the American Medical Association, for articles published from June 6-12, 2026. Related Content: Audio Highlights

Artificial intelligence depends on the systems that manage and organize data. International Business University's MSc in Applied AI - Data Engineering specialization prepares students to build data infrastructure, support AI deployment, and work with large-scale systems used across finance, healthcare, logistics, and technology. International Business University City: Toronto Address: 655 Bay St. Website: https://ibu.ca/ Phone: +1 416 923 1111 Email: admission@ibu.ca

In this CruiseTipsTV Unplugged Q&A episode, we're answering your cruise questions on everything from Norwegian Luna and MSC Cruises to Japan trip planning, Alaska wildlife viewing, Royal Caribbean's Oasis Class ships, and even traveling to Japan with toddlers. We compare Princess and Viking in Japan, share our favorite spots on NCL Luna, discuss whether MSC might be right for your travel style, and offer practical advice for first-time Oasis of the Seas cruisers. Plus, we tackle jet lag strategies for Japan and talk about our favorite cruise lines and why. Later in the show, we spotlight two travel resources you may not know about. First, we share details on a unique new 100% gluten-free sailing with Celiac Cruise aboard Oceania Vista in 2028, designed for travelers with celiac disease and gluten sensitivities. Then we introduce Yes You Can Concierge, a service that may help simplify your travel planning. Whether you're planning your next cruise, dreaming about Japan, or just love talking travel, this episode is packed with tips, opinions, and inspiration. Shop our favorite cruise essentials on Amazon 

A great daily routine podcast. Enjoy! Alex Manos is a Certified Functional Medicine Practitioner with an MSc in Personalised Nutrition and a Distinguished Faculty Award from the Academy of Nutrition and Lifestyle Medicine. He lectures at the Institute of Optimum Nutrition and has spent years cracking the "mystery cases" — chronically ill patients who tried everything and couldn't get well. The missing link, almost every time, was mould.         

In this episode of AARC Perspectives, AARC President Dana Evans, MHA, RRT, RRT-NPS, FACHE, FAARC, FNAP, and American Respiratory Care Foundation (ARCF) Chair Carl Hinkson, MSc, RRT, RRT-NPS, RRT-ACCS, FAARC, FNAP, discuss how ARCF is shaping the future of respiratory therapy research, scholarships, international fellowships, and professional excellence. Evans and Hinkson discuss how AARC and ARCF are working together to expand the foundation's reach and impact. Whether through donations, participation in events, or the establishment of awards, there are numerous ways to support this vital organization. Learn more and support ARCF today.  Send us your thoughts on this podcastThank you for listening! Learn more at aarc.org 

In this episode, Al and Jenny meet Justin Gill. Justin became a follower of Jesus as a young man in his native Pakistan from where he immigrated to the UK. Immersed in post-industrial English communities for twenty years, he became well acquainted with the complex realities of race, poverty, religion, and questions of belonging. This conversation explores the turbulent relationship between Christianity, Islam and secularisation in a time of cultural and political instability. Justin senses that God has brought him, as a Christian, into Muslim contexts, and to be among the indigenous English working class. His love for peoples and place is evident in his deep understanding of these different communities' reactions to deindustrialisation, and how their responses to current tensions express their distinct histories and worldviews. Tying all this together is his deep conviction of Christ as Redeemer and His presence in hard, conflicted places.Justin Gill works with the Fellowship of Independent Evangelical Churches (FIEC), advising on cross-cultural mission in a network that links more than 50,000 Christians across the UK. Justin speaks here in a personal capacity. Born and raised in North Pakistan, he was an advisor on minority affairs to a political party and led relief operations following the 2005 earthquake. Moving to the UK in 2006, he gained an MSc in Development and Project Planning at Bradford University and lived in North Yorkshire. He continues to support evangelical church networks in Pakistan. He now lives in Leicestershire and attends Knighton Free Church.For Justin Gillhttps://fiec.org.uk/people/justin-gillhttps://fiec.org.uk/who-we-are/staffhttps://uk.linkedin.com/in/justin-gill-fiechttps://x.com/Justin4Gillhttps://fiec.org.uk/resources/moving-towards-intercultural-churchhttps://fiec.org.uk/resources/should-every-church-be-multi-racialFor Alan J Roxburgh:http://alanroxburgh.com/aboutFacebook: https://www.facebook.com/alan.roxburgh.127/Facebook: https://www.facebook.com/thecommonsnetworkBooks:Forming Communities of Hope in the Great Unravelling: Leadership in a Changing World (with Roy Searle)Joining God in the Great UnravellingLeadership, God's Agency and DisruptionsJoining God, Remaking Church, Changing the World: The New Shape of the Church in Our TimeFor Jenny Sinclair:Substack: https://t4cg.substack.com/s/from-jenny-sinclairWebsite: https://togetherforthecommongood.co.uk/from-jenny-sinclairLinkedIn: https://www.linkedin.com/in/jenny-sinclair-0589783b/Twitter: https://twitter.com/T4CGFacebook: https://www.facebook.com/TogetherForTheCommonGoodUKInstagram: https://www.instagram.com/t4cg_insta/ Get full access to Leaving Egypt at leavingegyptpodcast.substack.com/subscribe

In Part 2 of the ASCO 2026 Highlights series, hosts Dr. Narjust Florez and Dr. Stephen Liu are joined by Dr. Julie Brahmer and Dr. Solange Peters to discuss some of the most notable immunotherapy advances presented at the 2026 ASCO Annual Meeting. The conversation explores emerging data for PD-1/VEGF and PD-L1/VEGF bispecific antibodies, the growing role of antibody-drug conjugates in combination with immunotherapy, and promising new strategies targeting KRAS-mutant lung cancers, highlighting how these approaches may reshape the future treatment landscape. Guests: Julie R. Brahmer, MD, MSc, FASCO, FAIO The Marilyn Meyerhoff Professor of Thoracic Oncology Co-Leader, Cancer Immunology Research Program Co-Director, Upper Aerodigestive Cancers Program Director, Johns Hopkins Kimmel Cancer Center, Bayview Campus Professor Solange Peters, MD, PhD Chair of Medical Oncology Director of Oncology Department - CHUV Lausanne University Hospital

In this week's podcast, Property Elite's Abigail Blumzon hosts Katie Corbett and Karl Brown in a discussion about social mobility and the property & construction industry.Katie is a Social Value & EDI Manager at Bray & Slaughter, as well as being the Women in Property South West DEI Champion and holding a MSc in Equality & Human Rights.In her own words; With experience on both the consultancy and contractor sides of the industry, and an MSc in Equality and Human Rights, I bring a practical and informed approach to social value and EDI delivery. In my current role, I lead strategies that embed impact and inclusion into projects – managing partnerships, planning, delivery, progress reporting throughout the lifecycle, and final project reporting. Alongside this, I serve as the Diversity, Equity, and Inclusion Champion for the Women in Property South West Committee, where I advocate for industry-wide inclusion by organising events and initiatives across Bristol.Karl is a Partner at Clarke Willmott, a Business Fellow at UWE, a Social Mobility Ambassador to the Law Society and the Chairperson of the Bristol Property Inclusion Commission.The Commission consists of representatives from the Bristol property industry and supports the implementation of the Bristol Property Inclusion Charter. Karl founded and launched the Charter in November 2019 to be a vehicle to promote and drive diversity and inclusion in the Bristol property industry/sector. Many thanks also go to Ytzen van der Werf, Programme Leader MSc Real Estate Finance & Investment at UWE Bristol, who helped to set up this insightful discussion.

In this episode, hosts Chris and Mecca speak with Dr. Danny Longman and Dr. Colin Shaw about the mismatch between humans and modern built environments, exploring both the negative biological impacts of living in industrialized cities and the positive effects of spending time in nature. Dr Danny Longman graduated from the University of Cambridge with a BA (Hons) in Natural Sciences (2005–08), followed by an MPhil (2008–09) and PhD (2011–14) in Human Evolution. He remained at Cambridge as a Postdoctoral Researcher (2015–19) before joining Loughborough University as a Lecturer. He has since been promoted to Senior Lecturer. Outside of work, Danny is a keen sportsman with a passion for ultra-endurance sport, nature, and travel. Dr. Colin Shaw graduated from the University of Western Ontario (Canada) with a BA (Hons) in Anthropology and Kinesiology (2000) and an MSc in Exercise Physiology (2000-02), then moved to the University of Cambridge, where he obtained an MPhil (2003-04) and a PhD (2004–08) in Biological Anthropology. He was a postdoctoral researcher at the University of Wisconsin-Madison (2008-2009), Penn State (2010-2011), and the University of Cambridge (2011-2015). He is now a Senior Lecturer at the University of Zurich. ------------------------------ Find the paper discussed in this episode: Longman, D.P. and Shaw, C.N. (2026), Homo sapiens, industrialisation and the environmental mismatch hypothesis. Biol Rev, 101: 580-601. https://doi.org/10.1111/brv.70094 ------------------------------ Contact the Sausage of Science Podcast and the Human Biology Association: Facebook: facebook.com/groups/humanbiologyassociation/, Website: humbio.org Chris Lynn, Co-Host, Website: cdlynn.people.ua.edu/, E-mail: cdlynn@ua.edu Mecca E. Howe, Co-Host, E-mail: howemecca@gmail.com, LinkedIn: https://www.linkedin.com/in/mecca-howe/

In the June open access episode of Chattering With iCatCare, Yaiza Gómez-Mejías is joined by Mariana Lopes and Joanna Morris to explore feline oncology and the practical roadmap for using oral chemotherapy agents in general practice.  The conversation focuses on providing realistic treatment options for patients where referral may not be accessible, highlighting how oral protocols can achieve efficacy and maintain quality of life within a primary care setting. They also discuss why cats must not be treated as small dogs regarding drug toxicity and the specific challenges of monitoring feline patients who often hide side effects.For further reading material please visit:Oral chemotherapy agents in cats: clinical uses, administration and side effectsHost:Yaiza Gómez-Mejías, LdaVet MANZCVS (Medicine of Cats), RCVS CertAP (Feline Medicine), iCatCare Veterinary Community Co-ordinatorSpeakers:Mariana Lopes, DVM, MSc, MVM, MRCVS, DipECVIM-CA (Onc), European Specialist in Small Animal Oncology, University of GlasgowJoanna Morris, BSc, BVSc, PhD, FRCVS, FHEA, DipECVIM-CA (Onc), Professor of Veterinary Oncology, University of Glasgow

In today's episode, our hosts Tracey and Scott will present their coverage of the latest theatrical entry in the Star Wars universe: The Mandalorian and Grogu. After discussing its development and production, our hosts will take a look at the marketing and response to the film before sharing their thoughts. They'll also call over to the MSC before wrapping up the show with a look at upcoming episodes. Welcome to Disney, Indiana!

You have probably encountered claims that your “glutes aren't firing” or that you have “sleepy glutes,” and that lazy glutes are hurting your running. This approach misses a lot of nuance: if you can stand, your glutes work; but weak glutes can impact running injury risk and running economy. We are joined by Dr. Gaby Go, DPT and run coach, who explains the nuances of glute activation and why strong glutes matter for runners.Thank you to our sponsors:✨ Good Ranchers: American-grown meat, delivered frozen to your doorstep. Use code IRON for $40 off the first order, or$100 off across the first three orders when customers start a subscription. Plus free protein with every order (choice of burgers, bacon, or chicken breasts). Be sure to mention “Tread Lightly Podcast” for how you heard about the company! https://www.goodranchers.com/In this episode, you'll learn:✅ How the glutes and agonzing/antagonizing muscles work in your running stride✅ What does “glute activation” actually mean?✅ If squeezing your glutes while you run helps or harms✅ Signs and symptoms of underactive or weak glutes✅ Whether sitting all day harms your running or not✅ When to use bodyweight/banded glute exercises and when to progress them✅ How to know if you are doing too much strength training✅ Do you need to change your running form for optimal glute activation?Tread Lightly Running is hosted and researched by Amanda Brooks and Laura Norris, MSc. Production, show notes, and graphics by Laura Norris.Connect with our guest:Dr Gaby Go on Instagram: https://www.instagram.com/dr.gabygo/Work with Dr. Gaby Go at https://gorunstronger.com/Let's stay connected:➡️ Tread Lightly Running Podcast on Instagram: https://www.instagram.com/treadlightlyrunning/➡️ Laura Norris Running on Instagram: https://www.instagram.com/lauranorrisrunning/➡️ Subscribe for weekly evidence-based newsletters, straight to your inbox, on https://lauranorrisrunning.substack.com/➡️ Run to the Finish on Instagram: https://www.instagram.com/runtothefinish/?hl=en➡️ Thousands of running gear reviews and training guides: https://runtothefinish.com/

Fresh off the pitch from their 4th year of the MSC Cup fundraising event raising money for Rubin's Retreat, Antonio Paradiso tells Andy what makes their partnership so special. He also shares the latest updates from MSC including the extension of their lower deposit campaign, their next ship launch World Asia as well as addressing some recent concerns around fuel recharges and other initiatives including their "Best Holiday Ever" commitment to boost consumer and travel agent confidence to book their cruises. Explora Journeys is also looking forward to welcoming their newest ship Explora III which is the first LNG-powered ship in the fleet, and it provides the flexibility to utilise renewable fuels such as bio-LNG and synthetic LNG. Antonio also tells Andy how important the UK & Ireland market is to both of his brands and how excited he remains to grow both markets.

In this episode, we will be joined by Dion, who will discuss his passion for Dr. J.C. Burnett's work on organ remedies in homeopathy. Dion aims to reintroduce Burnett's ideas to a new generation of homeopaths, and he will share his insights on how these remedies can be applied to modern-day practice. With his extensive knowledge and expertise, Dion will delve into the fascinating world of organ remedies and shed light on how they can be utilized to achieve optimal results for patients. Dion Tabrett is a well-respected homeopath who has been practicing for over 20 years. He began his journey in homeopathy by studying at the London College of Homoeopathy, where he graduated in 1992 with the Licentiate of the College of Homoeopathy (LCH) and continued with postgraduate studies. Dion has since received several accolades, including the award of Member of the College of Homoeopathy (MCH) in 1994. In addition to his homeopathic education, Dion also pursued a BSc (Hons) in Natural Sciences in 2003 and an MSc in Molecular Biology in 2007 from the Open University, with a focus on human anatomy, physiology, and pathology.  Dion has worked in various clinics across the UK, including Berkshire, Cornwall, Devon, London, and Bristol. He has also taught at numerous colleges and universities, including the London College of Homeopathy, Bristol College of Homeopathy, and the Centre of Homeopathic Education in London, where he currently works as the Clinical Skills and Casework module leader for the BSc course. Dion is known for his easy-going and approachable style of teaching, and his ability to inspire and educate students at all levels. Dion is also a self-confessed "Compton Burnett geek," and is the author of the book "Burnett Rediscovered," which explores the life and work of Dr. J.C. Burnett, a prominent British homeopath of the late 19th and early 20th centuries. Dion's book aims to rekindle interest in Burnett's work and reintroduce his ideas to a new generation of homeopaths. Check out these episode highlights: 01:55 - How he first discovered homeopathy 05:40 - What is an organ remedy 11:33 - The process that takes place in writing his book called Burnett Rediscovered 14:39 - The importance of using organ remedies 21:14 - Dion's preference in prescribing organ remedies 25:17 - The myth surrounding nosodes 29:55 - Who was Francisco Xavier Eizayaga, and what was his homeopathic approach 37:52 - Dion's final message  Find out more about Dion Website: https://www.diontabrett.com/ Purchase Dion's book through Eugenie's Amazon Affiliate link to help support the Homeopathy Hangout podcast: https://amzn.to/3RAigj6 If you would like to support the Homeopathy Hangout Podcast, please consider making a donation by visiting www.EugenieKruger.com and click the DONATE button at the top of the site. Every donation about $10 will receive a shout-out on a future episode.   Join my Homeopathy Hangout Podcast Facebook community here: https://www.facebook.com/groups/HelloHomies Follow me on Instagram https://www.instagram.com/eugeniekrugerhomeopathy/   Here is the link to my free 30-minute Homeopathy@Home online course: https://www.youtube.com/watch?v=vqBUpxO4pZQ&t=438s   Upon completion of the course - and if you live in Australia - you can join my Facebook group for free acute advice (you'll need to answer a couple of questions about the course upon request to join): www.facebook.com/groups/eughom

The first interview in the PRF Spotlight Series: Voices Shaping Pain Science features Dr. Michael Gold, PhD delving deep in to discussion of the history and future of sodium channels. From the identification of sodium channels as drivers of nociceptor excitability to the emergence of NaVs as therapeutic targets, this conversation bridges the history of pain research with the future of mechanism-based analgesia. Part 1 of our interviews on Sodium Channels and the Making of a Field.   Michael Gold, PhD University of Pittsburgh   Francisco Isaac  Gomes-Aragão, DDS, MSC, PhD University of São Paulo, BR   Beatriz Lima Adjafre, PhD University of São Paulo, Br   Music by Seal Party.   

Dr Erin Louise Bellamy  Dr Erin Louise Bellamy is a Chartered Psychologist, Metabolic Psychiatry Practitioner, and CEO of IKRT (ikrt.org), an international organisation advancing ketogenic metabolic therapy (KMT) for mental health.  She holds a PhD in Psychology (ketogenic diets and depression) and a master's degree (MSc) in Psychiatric Research from King's College London and is a Research Fellow at the University of East London.  With over a decade of experience researching and implementing KMT, Erin integrates clinical practice, education, and research to improve mental health outcomes. She is an Associate Fellow of the British Psychological Society and a member of the Society of Metabolic Health Practitioners. Link to Show Notes on Website https://fabulouslyketo.com/podcast/262 Dr Erin’s Top Tips If you’re dealing with mental health symptoms, consider ketogenic therapy. Use ketogenic therapy if you are taking any medications to offset the negative side effects Approach ketogenic therapy with the same daily commitment as you would if it was medication Resources Mentioned New Atkins For a New You: The Ultimate Diet for Shedding Weight and Feeling Great – Dr Eric C Westman, Dr Stephen D Phinney and Dr Jeff S Volek Connect with Dr Erin Louise Bellamy on social media Twitter: https://x.com/erinlbellamy and https://x.com/ikrt_org Facebook Page: https://www.facebook.com/profile.php?id=61554863570171 Instagram: https://www.instagram.com/erinlouisebellamy/ and https://www.instagram.com/ikrt_org/ LinkedIn: https://www.linkedin.com/in/erin-louise-bellamy/ and https://www.linkedin.com/company/integrative-ketogenic-research-and-therapies YouTube:https://www.youtube.com/@FabulouslyKeto Website Details: https://www.ikrt.org The Fabulously Keto Diet & Lifestyle Journal: A 12-week journal to support new habits – Jackie Fletcher If you have enjoyed listening to this episode – Leave us a review By leaving us a review on your favourite podcast platform, you help us to be found by others. Support Jackie Help Jackie make more episodes by supporting her. If you wish to support her we have various options from one off donations to becoming a Super Fabulously Keto Podcast Supporter with coaching and support. Check out this page for lots of different ways to support the podcast. https://fabulouslyketo.com/support Or You can find us on Patreon: https://www.patreon. com/FabulouslyKeto Connect with us on social media https://www.facebook.com/FabulouslyKeto https://www.instagram.com/FabulouslyKeto1 https://twitter.com/FabulouslyKeto https://www.youtube.com/@FabulouslyKeto Facebook Group: https://www.facebook.com/groups/FabulouslyKeto Music by Bob Collum Recommend a guest We would love to know if you have a favourite guest you would like us to interview. Let us know who you would like to hear of if you have a particular topic you would like us to cover. https://fabulouslyketo.com/recommend-a-guest We sometimes get a small commission on some of the links, this goes towards the costs of producing the podcast.

In this episode, Rob Jones is back in person and joins Tom for a wide-ranging conversation covering everything happening at InnerFight Endurance — Chamonix camp, LRC 3.0, Performance Camp in Korfakan, and the Athens Marathon in November.Tom shares how his return to zone 2 running triggered a dramatic jump in HRV, they dig into aid station efficiency data from Ultra Trail Snowdonia and UTMB, and Tom breaks down what his MSc has taught him about brain chunking, visual perception, and why the small habits around training matter more than most people think.They wrap up by getting into how the IFE coaching team is now using AI — not to replace coaching, but to handle the deep analysis that used to take hours and give that time back to the athlete.

Holland America unveils 'Evolution' — a $500 million-plus renovation of six classic ships, the largest investment in the line's 153-year history, beginning with Oosterdam's drydock and adding new suites, solo verandahs, and a Grand Dutch Café. And Explora Journeys launches the bow section of Explora V at Fincantieri's Palermo shipyard, the LNG-powered fifth ship in MSC's luxury fleet expansion bound for delivery in 2027.

Rates are climbing, carriers are piling on surcharges, and peak season is arriving ahead of schedule. This week Lars Jensen runs the numbers on why the market is where it is and it has everything to do with the Red Sea and almost nothing to do with how consumers are feeling.In this episode, Lars Jensen and Caroline Weaver cover:Why Pacific and Asia-Europe spot rates continue their upward momentum and what the futures curve is signaling for peak season, including a sharp expected pullback as early as SeptemberThe statistical relationship between US consumer sentiment and container volumes: Lars ran the analysis and the correlation coefficient is 0.3. There effectively isn't one.Hormuz update: no deal, drone strikes on Kuwait, a suspected mine in Omani waters, and an MSC 18,000 TEU vessel that went dark for five days and reappeared off West AfricaHow CMA-CGM continues to quietly expand its Suez routing while every other carrier goes around AfricaChina PMI at exactly 50, and why the raw materials sub-index shooting above 60 post-Hormuz is the inflation signal worth watchingGlobal trade imbalances since 2019: full containers up 17%, fleet up 43%, TEU miles up 41% and empty container movements up 102%

In our last episode, we discussed the physiology of running in the heat, including why you run slower. However, you are not doomed to suffer through slow slogs all summer long. In part two of our summer running series, we discuss heat acclimation strategies and cooling techniques to make summer running a little less miserable.Thank you to our sponsors:✨Title Nine: Comfortable sports bras that actually fit, from a women-owned company. Use code RUNTOTHEFINISH for free shipping at https://runtothefinish.com/title-nine/✨ Mizuno: Shop Mizuno's newest bouncy supertrainer: https://runtothefinish.com/neovista3/In this episode, you'll learn:✅ How long it takes to acclimate to running in the heat✅ If year-round heat acclimation is beneficial✅ Pre- and mid-run cooling techniques for running in the heat✅ If hyperhydration strategies work?✅ How much sodium you need for summer runs✅ Signs and symptoms of heat illnessReferences

This EAUN episode features an interview with the faculty of the hands-on training on erectile dysfunction. Jeannette Verkerk-Geelhoed (NL), MSc, PhD candidate and CNS at St. Antonius Hospital, specialising in male sexual health including erectile dysfunction and Peyronie's disease, is joined by Phil Reynolds (GB), MSc, BSc, HNC, radiographer at Clatterbridge Cancer Centre with a holistic focus on prostate cancer care, and Mariet Lenaers (BE), MSc, BN, prosthetic nurse at Virga Jesse Hospital, specialising in counselling patients undergoing prosthetic treatment.Together, they reflect on the EAUN26 hands-on training session, focusing on the impact of sexual dysfunction in men and what it means for patients and their partners. The discussion highlights both the physical and psychological aspects of erectile dysfunction, as well as the importance of communication and patient education. The faculty also review current treatment options, including oral medication, vacuum devices, intracavernosal injections, and, as a final option, penile prosthesis.For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

Dr. Dirk Willer is a Managing Director and Global Head of Macro and Asset Allocation at Citi Research in New York. Prior to this role, Dirk headed global Emerging Market Strategy, where he and his teams were consistently ranked in the top three in the institutional investor surveys. Previously, Dirk worked at Omega Advisors and RHG Capital as a global macro strategist and portfolio manager, and at Swiss Bank as a fixed income strategist for Russia and Eastern Europe. Dirk holds a PhD and MSc in Economics from the London School of Economics. Dirk is also the author of an influential book on how to trade emerging market fixed income, published by Wiley in 2020, and of a book on global macro trading, released in 2026. In this podcast, we discuss: Unlearning the QE Reflex Trading "Close to the Fire" The Nearest Neighbour Regime Framework PMIs vs. "Noisy" Indicators Yield Curve Inversions and Fed Lags The "GMO" Bubble Methodology Credit as the Equity Canary The Four-Indicator Dollar Model Fading Geopolitical Shocks The Role of Human Judgment in AI 

Episode 153In this episode of Cruise Conversations, we're catching up on some of the biggest recent developments in the cruise industry, from new private destination updates to major ship renovations and future cruise plans. We cover:• Carnival officially opens Isla Tropicale at Mahogany Bay• The latest delays and environmental concerns surrounding Royal Caribbean's Perfect Day Mexico• New dining upgrades added to MSC Seashore• Major amplification updates added to Harmony of the Seas• Virgin Voyages and MSC are preparing for their first Alaska seasons• And a look at the future of cruising with nearly $90 billion in new ships currently on order across the industryReady to book a cruise with Cruise Conversations?⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Fill out our form or send us a text at (704) 313-8556 for latest pricing!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Check out our website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.cruiseconversationspodcast.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Use our code "CC15" for 15% off your order at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠The Cruise Maps⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Interested in coming on a future episode and recapping your cruise? Fill out the following form: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://form.jotform.com/252443162720146⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Have a question or topic suggestions for a future episode? DM us on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@CruiseConversations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ or send us an email at cruiseconversations@gmail.com.Follow along on social media!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Tik Tok⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Cada vez vemos más niños pasan varias horas frente a las pantallas; tabletas, computadoras, celulares, ya que todas ellas forman parte de la vida escolar y del entretenimiento. Por ende, muchos padres empiezan a notar algo preocupante, los ojos se ponen rojos, se irritan, arden y hay una sensación como de arenilla. ¿Estamos viendo más síndrome de ojo seco en niños? ¿Qué relación tiene la salud visual con las pantallas y la miopía? Para hablar sobre el síndrome de ojo seco, el síndrome visual informático y la relación de los dispositivos con la progresión de la miopía en niños, nos acompaña la Dra. Rosario Gulias. La Dra. Rosario Gulias es médico oftalmólogo egresada de la Asociación para Evitar la Ceguera en México, subespecialista en estrabismo, con MSc y PhD en Biología Celular por el CINVESTAV. Se dedica a clínica, docencia e investigación traslacional en ojo seco y superficie ocular. Instagram: @vivesinojoseco ¿Tienes algún comentario sobre este episodio o sugerencias de temas para un futuro podcast? Escríbenos a pediatrasenlinea@childrenscolorado.org.

The Journal of Arthroplasty: The Cut brings you another very special episode based on Knee Society Proceedings that highlight important research about knee arthroplasty. In this episode of The Cut, our hosts Kim K. Tucker, MD, and Nathanael D. Heckmann, MD welcomed guests Ran Schwarzkopf, MD, MSc and Christopher E. Pelt, MD to discuss three different papers, all focusing on corticosteroid injections – do they actually help and at what cost? These injections have long been a part of the diagnostic and therapeutic toolkit, but recent data raise questions about their durability and safety—particularly before arthroplasty. Our gracious guests responded to questions such as how they counsel patients requesting a hip CSI given this limited benefit and potential infection signal, how they plan fixation when bone quality is compromised from RPOA and if there are posterior-specific technical pearls (capsular repair, retractor placement) that help minimize GT pain and so much more!  In this recording, our guests tackle three different angles of corticosteroid use, but a common thread between them all were that they're not as benign as once thought. For more, listen to the full recording here. Thanks for listening to The Journal of Arthroplasty: The Cut! In This Episode:Nathanael D. Heckmann, MDChristopher E. PeltRan Schwarzkopf, MD, MScKim K. Tucker, MD The post Corticosteroid Injections and the Hip first appeared on AAHKS.

Miki Feldman Simon, MSc, PCC, is an executive coach, global business leader, speaker, and author of CORE Leadership: A Four-Step Framework to Lead Yourself, Grow Your Influence, and Amplify Your Impact. Over her three-decade career, she has held leadership roles in marketing, operations, and HR across multiple industries and guided organizations through growth and successful acquisitions. In her coaching, she helps leaders align values and actions to lead with greater clarity and influence. Known for her warmth, sharp insight, and candor, she blends behavioral science with practical tools that drive lasting change.In today's episode of Smashing the Plateau, you will learn how leading yourself first can transform the way you show up as a leader and build deeper influence with the people around you.Miki and I discuss:Miki's non-linear career journey across Israel, Australia, and the US [02:56]How unexpected career breaks shaped her leadership philosophy [05:28]Why leadership starts with leading yourself [12:26]The CORE framework: Clarify, Operationalize, Reflect, Evaluate [13:19]How habit stacking builds intentional leadership [15:42]Understanding self-talk and limiting beliefs [17:21]The gap between intentions and impact [19:18]Real results leaders experience through the CORE framework [20:31]The role of curiosity and psychological safety in community [23:39]Learn more about Miki at https://mikifeldmansimon.com/ and https://www.linkedin.com/in/mikifeldmansimon/______________________________________________________________About Smashing the PlateauSmashing the Plateau is a podcast for experienced independent leaders who have left corporate roles to build sustainable, expertise-based businesses.Each episode features a thoughtful, experience-driven conversation about what changes when you no longer have the infrastructure of an organization behind you.We explore judgment, decision-making under uncertainty, growth plateaus, identity shifts, and the role of trusted thinking partners in sustaining long-term success.______________________________________________________________Take the Next Step• Experience the power of peer perspective.Join a live guest session and connect with experienced professionals navigating similar challenges:https://smashingtheplateau.com/guest• Stay connected to the conversation.Get new episodes, reflections, and invitations delivered to your inbox:https://smashingtheplateau.com/news

This week we are joined by Mickey Trescott! Mickey Trescott, MSc, is an author, recipe creator, and holistic nutrition professional, widely recognized for her expertise in living well with autoimmune disease. She holds an MSc in Human Nutrition and Functional Medicine from the University of Western States and is a certified Functional Nutritional Therapy Practitioner. Trescott has been working in private practice as a functional nutritionist for over a decade and has written three award-winning books: The Autoimmune Paleo Cookbook, The Autoimmune Wellness Handbook, and The Nutrient-Dense Kitchen. Check out her website and Podcast! In this episode, Mickey Trescott shares her journey from growing up in California to becoming a prominent figure in the autoimmune wellness community. She discusses her personal experiences with chronic illness, the challenges of navigating the healthcare system, and how these led her to explore nutrition and recipe development. Mickey also highlights her work in educating others about autoimmune protocols and her passion for helping people manage their health through diet and lifestyle changes.  Recommendations From This Episode:  Food Revolution Network Hungryroot The New Autoimmune Protocol Follow Mickey: @mickeytrescott Follow Carly: @carlyjmontag Follow Emily: @thefunnywalsh Follow the podcast: @aloneatlunchpod Please rate and review the podcast! Spread the word! Tell your friends!  Email us:  aloneatlunch@gmail.com Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Dr Funmi Okunola MD interviews Dr Guillaume Dedet MD, MPH, MSc, MA - Senior Health Economist at the Organisation for Economic Co-Operation and Development (OECD) andDr David Kelly MD, MPH, MRCIP, CSCST - Public Health Physician & Epidemiologist at the OECD about their April 2026 report - "Addressing the Costs & Care of Long COVID for Long COVID the Long Shadow of the Pandemic". We also dive into their October 2025 OECD report - "The Prevalence and Impact of Long COVID in the Primary Care Population - Findings from the OECD PaRIS Survey".REFERENCES 1. Addressing the Costs & Care of Long COVID for Long COVID the Long Shadow of the Pandemic. 2. The Prevalence and Impact of Long COVID in the Primary Care Population - Findings from the OECD PaRIS Survey

Ever been told “You're so strong… You're so resilient” but it feels like you're not? Well, you could actually just be good at ‘enduring' and today's guest wants to help you feel like you can move through difficult chapters and truly feel resilient and strong. Dr. Suzan Song is a Harvard- and Stanford-trained psychiatrist and medical anthropologist who has worked with families and people facing crisis around the world. She is the author of Why We Suffer and How We Heal, exploring how narrative and everyday rituals help us build resilience in uncertain times.You'll learn:What making meaning from difficult experiences or events looks likeThe difference between endurance and resilienceWhen to move on from the phase of ‘this is bad and feels unfair' How to build a powerful family legacy through generationsThe role of rituals in resilienceAnd more. I truly hope it helps, Alexx StuartYour HostFancy a few more podcasts we've done over the years, related to this one?Show #390 Somatics: How to Make your Journey Real and True with Irene Lyon, MSc.Show #405 It's not you, it's your nervous system: How to tell the difference with Jessica MaguireShow #352 – Psychologist Alex Howard Says It's Not Your FaultShow #447 The Biology of Trauma: Uncover, Understand, and Heal with Dr. Aimie ApigianShow #271 – Melanie Salmon: Healing Trauma with QECShow #240 – Dr Carrie Rigoni: Vagus Nerve Health for Babies, Kids, and ParentsWant to learn more about this week's guest? Website: www.suzansong.com Instagram: https://www.instagram.com/drsuzansong Book: https://bit.ly/4c5Jla2 Thank you to this month's show partners for joining us to help you make your low tox swaps! @waterscofilters with an additional 15% off their BIO POT 500 5.25L with code LOWTOXWATER - take all the bad stuff out + keep all the deeply hydrating minerals IN with 13 stages of filtration. (Ensure you tick ‘one time' and not the default ‘subscription' when adding to cart) https://bit.ly/4fQZqPp @weledaaustralia with 25% off site-wide at weleda.com.au code LOWTOXLIFE to stock up on faves or make your first exciting low tox swaps - enjoy! @ausclimate is our major partner giving you 10% off their range for the whole of 2025, with brilliant Winix Air Purifiers, the best Dehumidifiers I've ever used and their new energy-efficient heating, air-circulating and cooling range. code LOWTOXLIFE (also works over and above their sales - pro tip!) https://bit.ly/ShopAusclimateBe sure to join me on Instagram @lowtoxlife and tag me with your shares and AHAs if something resonated! I love to see your thoughts, genuinely! Want to support the Low Tox Life podcast? Free option: Leave a 5 star review wherever you listen to Low Tox Life - thanks SO much! Paid + Member PERKS: Join the Low Tox Club - monthly practitioner live masterclasses, a suite of low tox store discounts from around the world and the most supportive and lovely chat group on all low tox topics on the internet: Check it out and join here for just the price of a coffee per month! Hosted on Acast. See acast.com/privacy for more information.

It doesn't have to be a cruel summer of slogging through hot, humid runs. You can adjust your training so that summer running is productive and enjoyable. In part 1 of our summer running episodes, we discuss the physiological impacts of running in the heat and humidity, and how to adjust your training based on those responses.Thank you to our sponsors:✨ Good Ranchers: American-grown meat, delivered frozen to your doorstep. Use code IRON for $40 off the first order, or$100 off across the first three orders when customers start a subscription. Plus free protein with every order (choice of burgers, bacon, or chicken breasts). Be sure to mention “Tread Lightly Podcast” for how you heard about the company! https://www.goodranchers.com/✨ Tailwind: Complete sport nutrition made simple, including hydration mixes, high-carb sport drinks, endurance fuel, and recovery mixes. Use code TREADLIGHTLY20 at https://tailwindnutrition.com/TREADLIGHTLY for 20% off your first purpose.✨ Mizuno: Shop running shoes and clothes at Mizuno's Memorial Day sale: https://runtothefinish.com/memorial-day-sale-mizuno-usa/In this episode, you'll learn:✅ What happens to your body when you run in the heat✅ Why you need to change your recovery strategy during the summer✅ Why humidity, UV index, and air quality, matter as much as temperature✅ How to adjust your paces for running in the heat✅ How to adjust your interval and tempo runs for the heat and humidityFurther Resources:Heat-Adjusted Pace Calculator: https://apps.runningwritings.com/heat-adjusted-pace/How to Adjust Your Workouts for Heat and Humidity: https://lauranorrisrunning.substack.com/p/how-to-adjust-your-running-workoutsReferences

Two weeks away and the Golden Crew comes back swinging — through some technical chaos that briefly ejected Tom from his own show (we're fine, he's fine, the audio's mostly fine).

About this episode: In the city of Baltimore, the health department works to prevent overdose, reduce violence, provide vaccinations, inspect restaurants, and so much more. In this episode: Host Stephanie Desmon leads a panel discussion with five Baltimore City Commissioners of Health who collectively served over three decades. They swap stories and speak candidly about the challenges and opportunities of the role. Guests: Dr. Peter Beilenson, MPH, is a lecturer at the Johns Hopkins Kreiger School of Arts & Sciences. He served as the Baltimore City Commissioner of Health from 1992 to 2005. Dr. Letitia Dzirasa is the Deputy Mayor of Health and Human Services with the City of Baltimore. She served as the Baltimore City Commissioner of Health from 2019 to 2023. Dr. Josh Sharfstein is distinguished professor of the practice in Health Policy and Management, a pediatrician, and former secretary of Maryland's Health Department. He served as the Baltimore City Commissioner of Health from 2005 to 2009. Dr. Michelle Taylor, DrPH, MPA, is the Baltimore City Commissioner of Health. She also serves in the Tennessee Air National Guard, and she previously led operations at the Shelby County Health Department. Dr. Leana S. Wen, MSc, is a physician and professor of health policy and management at George Washington University. She served as the Baltimore City Commissioner of Health from 2014 to 2018. Host: Stephanie Desmon, MA, is a former journalist, author, and the director of public relations and communications for the Johns Hopkins Center for Communication Programs. Show links and related content: Health Commissioner Michelle Taylor is Betting on Baltimore—Public Health On Call (May 2026) Baltimore's Record Low in Homicides—Public Health On Call (November 2025) Baltimore's Back-to-Back Mass Overdoses—Public Health On Call (September 2025) B'More for Healthy Babies: A Look Back at 15 Years of Infant Mortality Reduction in Baltimore—Public Health On Call (May 2025) Transcript information: Looking for episode transcripts? Open our podcast on the Apple Podcasts app (desktop or mobile) or the Spotify mobile app to access an auto-generated transcript of any episode. Closed captioning is also available for every episode on our YouTube channel. Contact us: Have a question about something you heard? Looking for a transcript? Want to suggest a topic or guest? Contact us via email or visit our website. Follow us: @‌PublicHealthPod on Bluesky @‌PublicHealthPod on Instagram @‌JohnsHopkinsSPH on Facebook @‌PublicHealthOnCall on YouTube Here's our RSS feed Note: These podcasts are a conversation between the participants, and do not represent the position of Johns Hopkins University.

Send us Fan MailMickey Trescott, MSc, is an author, nutrition professional, and leading voice in the Autoimmune Protocol (AIP) community. She holds a Master of Science in Human Nutrition and Functional Medicine and has supported autoimmune clients in private practice since 2013.As co-founder of Autoimmune Wellness, she helped grow AIP from a small online community into a globally recognized, research-supported protocol. She has collaborated with medical researchers studying AIP for conditions including inflammatory bowel disease, Hashimoto's thyroiditis, rheumatoid arthritis, and psoriasis, and co-created the AIP Certified Coach Practitioner Training Program, which has trained more than 1,000 providers worldwide.She is the author of four award-winning and best-selling books, including The New Autoimmune Protocol, which introduces the first major update to AIP in over a decade. She lives near Portland, Oregon, with her husband, Noah.https://autoimmunewellness.com/Use code FA FOR 40% OFF Athletic greens is a non-negotiable part of my daily routine. With 75 absorbable vitamins and minerals in just one scoop a day, I have increased my energy, improved my immune function and so much more. To get your own AG at 20% off go to www.athleticgreens.com/functionallyautoimmune Order now for a free vitamin D3/K2 supplement and 5 free travel packs!Support the show

Stephen Grootes speaks to Alex Thomson, co-founder of Naked Insurance, about the company’s launch of a world-first ChatGPT-native app that can generate final, binding car insurance quotes and what it signals about the future of AI-driven financial services. In other interviews, Ross Volk, Managing Director of MSC Cruises South Africa, talks about the company’s strong 2025/2026 South African cruise season, which saw more than 85 000 passengers sail aboard MSC Opera across 37 voyages, the growing popularity of cruise holidays among South Africans particularly travellers from Gauteng and the broader tourism and economic impact of the sector. The Money Show is a podcast hosted by well-known journalist and radio presenter, Stephen Grootes. He explores the latest economic trends, business developments, investment opportunities, and personal finance strategies. Each episode features engaging conversations with top newsmakers, industry experts, financial advisors, entrepreneurs, and politicians, offering you thought-provoking insights to navigate the ever-changing financial landscape.    Thank you for listening to a podcast from The Money Show Listen live Primedia+ weekdays from 18:00 and 20:00 (SA Time) to The Money Show with Stephen Grootes broadcast on 702 https://buff.ly/gk3y0Kj and CapeTalk https://buff.ly/NnFM3Nk For more from the show, go to https://buff.ly/7QpH0jY or find all the catch-up podcasts here https://buff.ly/PlhvUVe Subscribe to The Money Show Daily Newsletter and the Weekly Business Wrap here https://buff.ly/v5mfetc The Money Show is brought to you by Absa     Follow us on social media   702 on Facebook: https://www.facebook.com/TalkRadio702 702 on TikTok: https://www.tiktok.com/@talkradio702 702 on Instagram: https://www.instagram.com/talkradio702/ 702 on X: https://x.com/CapeTalk 702 on YouTube: https://www.youtube.com/@radio702   CapeTalk on Facebook: https://www.facebook.com/CapeTalk CapeTalk on TikTok: https://www.tiktok.com/@capetalk CapeTalk on Instagram: https://www.instagram.com/ CapeTalk on X: https://x.com/Radio702 CapeTalk on YouTube: https://www.youtube.com/@CapeTalk567 See omnystudio.com/listener for privacy information.

Are you stuck in a cycle of inflammation with no clear answers? Autoimmune conditions can be confusing, frustrating, slow to diagnose, and sometimes take years to understand.  In this episode, I am chatting with Mickey Trescott, a leading expert on the Autoimmune Protocol (AIP), about her decade of research and personal experience managing autoimmune disease. We talk about the modified AIP, exploring why it isn't just a diet but a structured healing process.  Mickey also shares insights from clinical studies on IBD, Hashimoto's, and psoriasis, and explains how elimination and reintroduction phases help people discover their personal triggers. You'll learn how to approach food as medicine, adapt the protocol to your lifestyle, and reintroduce foods safely.  Plus, Mickey offers simple tips to help you calm inflammation, restore gut balance, and finally feel empowered in your autoimmune journey.   "There is no cure for autoimmune disease, but I really believe that we can manage and live well with it." ~ Mickey Trescott   In This Episode: - How AIP differs from traditional elimination diets - The real goal of the AIP diet - Clinical results from AIP studies - Modified vs core autoimmune protocol - Food sensitivity testing explained - Delayed reactions and cross-reactivity - Mickey's autoimmune flare story - The New Autoimmune Protocol book overview   Products & Resources Mentioned: Mickey's Books on Autoimmune Wellness: Pre-order The New Autoimmune Protocol book and buy other books on Autoimmune Protocol at https://theautoimmuneprotocol.com/books/#naip  Tru Energy Skincare Bio Adaptive Hydration Oil: Try the oil and save up to $197 at http://trytruenergy.com/wendy5  Organifi Collagen: Save 20% with code MYERSDETOX at https://organifi.com/myersdetox  Organifi Happy Drops: Save 20% with code MYERSDETOX at https://organifi.com/myersdetox    Puori Grass-Fed PW1 Whey Protein: Use code WENDY20 to save up to 32% off your order and a free shaker worth $25 at https://puori.com/wendy20  Heavy Metals Quiz: Check your toxicity score and receive a free video series on how to detox your body at https://heavymetalsquiz.com    About Mickey Trescott: Mickey Trescott, MSc, is a leading advocate of the Autoimmune Protocol (AIP). She holds a Master of Science in Human Nutrition and Functional Medicine and has been practicing as a coach since 2013. As co-founder of Autoimmune Wellness, Mickey helped grow AIP from a grassroots online experiment into a globally recognized, research-supported protocol used by patients and practitioners around the world. In 2017, she co-created the AIP Certified Coach Practitioner Training Program, which has since trained more than 1,000 healthcare providers worldwide. She is the author of three award-winning and best-selling books, and The New Autoimmune Protocol. Learn more at https://theautoimmuneprotocol.com/  Disclaimer The Myers Detox Podcast was created and hosted by Dr. Wendy Myers. This podcast is for information purposes only. Statements and views expressed on this podcast are not medical advice. This podcast, including Wendy Myers and the producers, disclaims responsibility for any possible adverse effects from using the information contained herein. The opinions of guests are their own, and this podcast does not endorse or accept responsibility for statements made by guests. This podcast does not make any representations or warranties about guests' qualifications or credibility. Individuals on this podcast may have a direct or indirect financial interest in products or services referred to herein. If you think you have a medical problem, consult a licensed physician.

Editor-in-Chief Cecelia E. Schmalbach, MD, MSc, is joined by senior author Lee P. Smith, MD, and Associate Editor Christopher Johnson, MD, to discuss the study and approach used to establish a reliable rabbit model of airway stenosis and test how effective nebulized ciprofloxacin/dexamethasone is at reducing airway obstruction , as outlined in the paper "Evaluating the Efficacy of Nebulized Ciprofloxacin-Dexamethasone Using a Novel Model of Airway Stenosis" which published in the May 2026 issue of Otolaryngology–Head and Neck Surgery. Click here to read the full article. Click here to see the visual abstract.  

Dr. Deb Muth 00:04What if the future of healing isn’t about replacing cells, but about teaching your body how to heal itself again? We keep hearing the words stem cells and exoomes thrown around like they’re interchangeable, but they’re not. One is regulated, controversial, and often misunderstood. The other is rapidly emerging as one of the most exciting communication systems in human biology. Dr. Deb Muth 00:33And here’s the real question no one’s asking. Are we actually regenerating tissue or are we just stimulating the body to remember how it used to heal? Tired of being told your labs are normal, but you still feel terrible? At Serenity Healthcare Center, we don’t chase symptoms. We find the root cause. hormones, gut health, autoimmune conditions, chronic fatigue, brain fog. Dr. Deb Muth 01:02We use cuttingedge functional and regenerative medicine to get you real answers and a real path forward. This isn’t your average doctor’s office. This is medicine the way it was meant to be practiced. You deserve to feel like yourself again. Visit serenityhealthcarecenter.com to book your appointment today. Let us help you heal from the inside out. Dr. Deb Muth 01:28Welcome back to Let’s Talk Wellness Now. I’m Dr. Deb, your host. And if you’ve been following regenerative medicine, you’ve probably noticed the confusion. Patients are asking me every week, are exoomes stem cells? Are stem cells legal in the United States? I heard the FDA is shutting down all these clinics. Can I even get this therapy? Do I have to leave the country for treatment? Today, we’re cutting through the noise. This episode is not hype. Dr. Deb Muth 01:54It’s not sales. It’s education so you can understand the science, the regulatory reality, and the clinical difference between stem cell therapy and exoome therapy. And here’s what I want you to know right up front. Yes, these therapies are being used in the United States every single day. Yes, they’re being offered by highly trained physicians in integrative and regenerative medicine clinics across the country. Dr. Deb Muth 02:22Some are being used in FDA registered clinical trials. Some are being used in observational studies and some are being used in clinical practice under physician discretion. The landscape is nuanced and you deserve to understand it. So, grab your cup of coffee or tea and settle in for a deep dive into the most understood therapies in regenerative medicine. Dr. Deb Muth 02:43what they actually are, how they work, the regulatory landscape, and how they might support your body’s natural healing capacity. Let’s talk wellness now. So, let me start by asking you something. When you hear the word stem cell, what do you picture? Most people imagine damaged tissues magically regenerating or a torn meniscus growing back, cartilage reforming it into an arthritic joint or damaged brain tissue being replaced with healthy new beautiful cells. It’s a beautiful vision. Dr. Deb Muth 03:15And while it’s not quite that simple, the reality is actually more sophisticated and honestly more beautiful. Stem cells are powerful and they absolutely work, but the way they work and the mechanism by which they support healing is far more elegant and more so than most people really understand. And if you’re going to invest in regenerative therapy, you deserve to understand what you’re actually receiving. Dr. Deb Muth 03:44So, let’s start at the beginning. What are stem cells? At their core, stem cells are undifferentiated cells. That means they haven’t yet decided what they want to be when they grow up. Unlike a heart cell or a skin cell or a bone cell which have already committed to a specific function, stem cells exist in this beautiful state of potential. Dr. Deb Muth 04:05They have two remarkable abilities. First, they can self-renew. They can make copies of themselves, maintaining a reserve of these powerful cells throughout your lifetime. Second, they can differentiate under the right conditions. They can transform into specialized cell types. Bone cells, cartilage cells, nerve cells, muscle cells, even blood cells. Dr. Deb Muth 04:27This is why they’ve captured the imagination of the medical world. The potential is extraordinary. Now, there are several types of stem cells and understanding the differences matters tremendously for both understanding how they work and understanding how they’re regulated. Adult mezzenymal stem cells. We call these MSC’s are the most commonly used regenerative medicine. Dr. Deb Muth 04:54These come from bone marrow, atapost tissue, that’s fat, and other adult sources. They’re what we can call multi-potent, meaning they can become several types of cells, but not every type. A bone marrow stem cell isn’t going to become a brain cell, for instance. It has potential but it’s directed potential. Dr. Deb Muth 05:19Then we have perinatal stem cells. These come from umbilical cord blood cord tissue or something called Wharton’s jelly which is the gelatinous substance inside the umbilical cord. These cells are younger, more potent, and research by Weiss and colleagues published in stem cells back in 2006 showed that Wharton’s jelly derived MSC’s have superior proliferation and differentiation potential compared to bone marrow derived cells. Dr. Deb Muth 05:48They’re like comparing a 20-year-old athlete to a 50-year-old athlete. Both can perform, but one has more reserve capacity, more vigor, and more regenerative potential. And this isn’t this is very important because the perinatal sources umbilical cord tissue Wharton’s jelly amniotic tissue these are what many regenerative medicine clinics in the United States are using today and they’re using them because these tissues are incredibly rich in not just stem cells but growth factors cytoines and exoomes. Dr. Deb Muth 06:21Then there are embryionic stem cells. These are pur potent and they become any cell type in the body, but they’re highly regulated, ethically controversial, and honestly, they’re not being used in clinical practice in the United States outside of the very specific FDA approved research trials. Dr. Deb Muth 06:41So, when clinics talk about stem cell therapy, they’re almost never talking about embryionic stem cells. Now, here’s where it gets interesting and this is the part that changes everything about how we understand regenerative medicine. When you receive stem cell therapy, let’s say someone injects umbilical cord derived messenymal stem cells into your arthritic knee, those cells do not typically engraft or become new tissue in any permanent way. Dr. Deb Muth 07:12They don’t set up shop in your joint and start cracking out new cartilage cells for the rest of your life. So what are they actually doing then? Well, in 2011, researchers Arnold Arnold Kaplan and Dennis Korea published a landmark paper in stem cells translational medicine that fundamentally changed how we understand MSC therapy. Dr. Deb Muth 07:35They proposed that we should stop calling memal stem cells and start calling them medicinal signaling cells. Why? Well, because their primary therapeutic benefit doesn’t come from what they become. It comes from what they secrete. Think of stem cells as incredibly sophisticated biological pharmacies. When you inject them into damaged tissue, that arthritic knee, that inflamed autoimmune condition, that injured brain, that don’t just sit there passively, they sense the environment. Dr. Deb Muth 08:07They detect inflammation. They recognize the tissue damage and they understand that the immune dysregulation is present and they see that and respond. They start pumping out hundreds of bioactive molecules, growth factors that tell your cells to repair and rebuild, cytoines that modulate inflammation, chemocines that recruit your body’s own healing cells to the area. Dr. Deb Muth 08:32And these tiny membranes bound packages called extracellular vesicles, including exosomes, which we’re going to talk about extensively today as well. These secreted factors are giving instructions to your native cells. They’re saying, “Let’s reduce inflammation. Let’s modulate your immune response. Let’s promote angioenesis. Dr. Deb Muth 08:53” That’s the formation of new blood vessels, bringing nutrients and oxygen. Let’s stimulate your own resident stem cells to wake up and get to work. Reduce cell death in damaged tissue and restore normal cellular function. This is called paracrine signaling. It’s the cellto cell communication. And this is where the real therapeutic power lives. Dr. Deb Muth 09:14The stem cells themselves, many of them die within days to weeks, but the cascade of healing they trigger, the signals they send, the programs they activate in your own cells, those effects can last for months or even years. Now, this understanding is crucial because it explains why both stem cell therapy and exoo therapy can be effective. Dr. Deb Muth 09:38The stem cells are powerful not because they become new tissue but because of the signals they send and exoomes are those signals isolated and concentrated. The biggest misconception in regenerative medicine is that stem cells replace tissue and in reality they coach healing more than they become healing. They’re biological educators teaching your body to remember how it used to heal before chronic inflammation, toxicity, and disease turned off all those programs. Dr. Deb Muth 10:12So if stem cells don’t exactly end graft and become the new tissue, if their power is in their signaling and then next logical question is why do we need the cells at all? Well, if we could isolate the messengers themselves, what if we could deliver just the communication systems without any of the complexity of the living cells? Well, that’s exactly what exosomes are. Dr. Deb Muth 10:38And they represent the cutting edge of regenerative medicine. So, let me paint you a picture of how cells actually communicate. Because for most medical history, we had it wrong. For decades, textbooks taught us that cells talk to each other in two basic ways. through direct contact like shaking hands or releasing signaling molecules that floated through the extracellular space like messages in bottles, simple chemical messages. Dr. Deb Muth 11:09But in the 1980s and 90s, researchers started discovering something far more sophisticated. cells were releasing these tiny membrane bound packages like a biological FedEx envelope kind of you know it was filled with complex specific cargo and these packages could travel through the blood cross the barriers that normally keep things out like bloodb brain barrier and deliver their contents to distant cells with remarkable precision. Dr. Deb Muth 11:38These are called extracellular vesicles. And exoomes are one of the most therapeutic important types. So what exactly are exosomes? Well, they’re nanosized vesicles, typically 30 to 150 nanome in diameter. To put that into perspective, a human hair is about 100,000 nanometers wide. These are incredible and most impossibly tiny. Dr. Deb Muth 12:09They’re released by virtually all cells in the body, but the most therapeutically interesting exoomes come from mezenymal stem cells. And those medicinal signaling cells we just discussed. And according to a landmark review of Raposo and Stervogal, they published in the journal of cell biology in 2013, exoomes are not cellular debris. They’re not waste products. Dr. Deb Muth 12:35They are precisely engineered communication vesicles or vehicles. Think of them as sophisticated delivery systems carefully packed, carefully labeled, and sent to specific destinations. very specific instructions. Inside each of these exoomes, you’ll find an incredibly sophisticated payload. They are microRNAs. These are small RNA molecules that can literally turn genes off or on in the recipient cells. Dr. Deb Muth 13:06They can tell a cell to start making more collagen, to reduce inflammatory proteins, to activate repair programs that have been shut down by chronic disease for a very long time. There are messenger RNAs, actual templates for protein production. And exoome can deliver these instructions for making healing proteins. There are proteins themselves, growth factors, cytoines, enzymes, all the molecular tools a cell needs to heal. Dr. Deb Muth 13:34And there are lipids, specialized fats that help the exoome membrane fuse with targeted cells, delivering the cargo inside. When an exoome reaches its target cell, it can either fuse the cell membrane and deliver its contents directly inside like a Trojan horse, or it can bind to surface receptors and trigger signaling cascades, setting off a chain reaction of healing responses. Dr. Deb Muth 14:01Either way, it’s delivering very specific targeted instruction. And here’s what makes this so powerful. Those instructions are tailored to what this recipient cell actually needs. So, let me give you some concrete examples of what the research actually shows because this is where it really gets exciting. When researchers inject MSC derived exoomes into hearts that had experienced eskeeia, reprofusion, injury, that’s damaged blood flow being cut off and then being restored. Dr. Deb Muth 14:36Kind of like what happens during a heart attack. Something remarkable happened. A study by Lei and colleagues published in stem cell research in 2010 showed that exoomes significantly reduced the size of the damaged area, reduced inflammatory cytoines that drive tissue destruction and promoted tissue repair signaling. The exoomes were telling the heart cells stop the inflammatory cascade, activate your survival programs and repair the damage. Dr. Deb Muth 15:06In cartilage research, tow and colleagues published work in biioaterials in 2017 showing that exosomes derived from MSC’s could promote cartilage regeneration in osteoarthritis models. And the exoomes carried specific microRNAs that told condondroytes cartilage cells to proliferate and make more extracellular matrix, the structural framework of healthy cartilage. Dr. Deb Muth 15:30for autoimmune conditions. Research by Blazic and colleagues in Frontiers in Immunology in 2014 demonstrated that MSC derived exoomes could shift immune cell behavior from pro pro-inflammatory to regulatory. They could take an overactive self-attacking immune system and restore balance and promote tolerance. And perhaps most exciting brain research, a study by Zinn and colleagues published in the journal of extracellular vesicles in 2013 showed that MSC derived exoomes could cross the bloodb brain barrier. Dr. Deb Muth 16:07That protective shield around your brain that normally keep things out and promote neurological recovery in stroke models. They reduced brain inflammation, promoted neuroplasticity, supported the formation of neural connections, and for mitochondrial dysfunction, which underlies so many chronic conditions, Morrison and colleagues published research and scientific reports in 2017 showing that MSC derived exoomes can actually deliver functional mitochondria or mitochondrial components to damaged cells. They’re not Dr. Deb Muth 16:40just sending instructions, they’re sending spare parts. They’re restoring the cellular powerhouses to produce energy. So why are exoomes fundamentally different from stem cells? Well, exoomes contain no living cells. They can’t replicate. They can’t end graph. And they have virtually no risk of immune rejection or tumor formation. Dr. Deb Muth 17:03Concerns that exist elevate rarely with cellular therapies. They’re essentially biological software updates for your cells. As Fineian Pitiger wrote in their seinal review in stem cells in 2017, MSC derived exoomes represent the active ingredient of stem cell therapy delivered in a cellfree format. That’s the key insight in the in the therapeutic benefit of stem cells and it comes from what they excrete. Dr. Deb Muth 17:33Then exoomes are the secretion isolated, concentrated, and standardized. From a practical clinical standpoint, exoomes offer several compelling advantages. First, consistency. Because exoomes can be isolated, characterized, and standardized, each dose can be remarkably consistent. With living stem cells, there’s variability based on donor age, health status, processing methods, and one batch may be robust, but another might be weaker. Dr. Deb Muth 18:05With exoomes, you can measure the content, measure the potency, and ensure the quality control. Second is storage. Exoomes can be liophalized. They can be freeze-dried and stored at room temperature or refrigerated for extended periods. Stem cells require cryopreserv preservation, careful freezing, careful thawing. They’re fragile. Dr. Deb Muth 18:31Exoomes are remarkably stable. And third, their safety profile. Without living cells, the risk of adverse imunological reactions is dramatically lower. You’re not introducing foreign cells that your immune system might recognize and attack. You’re introducing molecular messages. Fourth is scalability. You can harvest millions, even billions of exoomes from stem cell cultures without ever injecting the cells themselves. Dr. Deb Muth 19:01And you can produce large quantities, standardize them, and make them available to patients. Now, there is a caution here in doing this. The scalability can produce rogue cells, and we want to be cautious of that. So, here’s what I need you to understand. Exoomes don’t force healing. They remind the body how healing works. Dr. Deb Muth 19:24They’re not replacing damaged cells. They’re re-educating the cells you already have. They’re turning back time on the biological programs that got turned off by inflammation, toxicity, trauma, time, and chronic disease. Your body knows how to heal. It’s done its entire life. Every cut that closed, every bone that mended, every infection you fought off, your body orchestrated that healing. Dr. Deb Muth 19:51The problem is that chronic disease, chronic inflammation, toxic exposures, poor nutrition, stress, all of these things disrupt the communication networks that coordinate healing. And exoomes restore that communication. They’re like rebooting a computer that’s frozen. They reset the system and remind it how it’s supposed to function. All right. Dr. Deb Muth 20:14So, this would not be complete if we didn’t talk about regulation because this is where a lot of confusion exists. And I want you to be given a real picture. Not fear-mongering, not pretending. There aren’t regulatory considerations, but the actual practical reality of how regenerative medicine is practiced in the United States today. Dr. Deb Muth 20:38Here’s what you need to understand. The FDA regulates these therapies and they have specific frameworks, but there’s important nuances between regulatory text enforcement priorities and actual clinical practice. And there are also state level regulations that provide additional pathways. The FDA regulates human cells, tissues, and cellular and tissue based products. Dr. Deb Muth 21:05We call them HCT/PPS under two main pathways. Section 361 products are those that meet specific criteria. They’re minimally manipulated, intended for homologous use, meaning these tissues perform the same basic function in the recipient as it did in the donor. They’re not combined with non-tissue components and they’re either autotogus, meaning they come from your own tissue, or they have had minimal systemic effect. Dr. Deb Muth 21:38An example of a clear 361 procedure, your doctor harvests your own bone marrow, we call this PRP, performs minimally processing to or uh perform Yeah. performs minimal processing to concentrate the stem cells through a centriuge and injects it into your arthritic knee the same day. That’s autogus same day but minimally manipulated. Dr. Deb Muth 22:04This is unquestionably legal and is being done in regenerative medicine clinics across the country every single day. So there’s section 351 where products are those that don’t meet all the section 361 criteria. They’re classified as drugs or biologic products and they require FDA approval through clinical trials. Dr. Deb Muth 22:27Now here’s where this gets more nuanced. There are regenerative medicine clinics across the United States using stem cell and exoome therapies in different contexts. First FDA registered clinical trials. These are formal research studies with investigational new drug applications. Patients enroll in trials. They sign informed consents. Dr. Deb Muth 22:48They receive therapies as part of their structured research protocols. And this is completely legal and represents the gold standard for gathering evidence. Second is observational studies and registry programs. Many clinics are collecting systemic data on patient outcomes using these therapies even outside the FDA trials. Dr. Deb Muth 23:12They’re documenting results, tracking safety, and contributing to the growing body of clinical evidence. Third, there’s clinical practice under physician discretion. There are physicians using these therapies based on their own clinical judgment informed consent from patients and their interpretation of the regulatory framework particularly around minimal manipulation and homologous use. Dr. Deb Muth 23:34Now there are also state regulations that provide additional legal frameworks. So, for example, Florida has enacted the Right to Try Act and specific regenerative medicine legislation that allows physicians to offer certain stem cell therapies under the state oversight. Utah has passed similar legislation creating pathways for regenerative medicine products. Dr. Deb Muth 23:57And these state laws recognize that patients should have access to potentially beneficial therapies, particularly when used by trained physicians with appropriate informed consent. The regulatory question often centers around are these products minimally manipulated. Some products clearly are not. They’ve been cultured. Dr. Deb Muth 24:20They’ve been expanded in laboratories and those require FDA approval that they don’t have. The FDA has appropriately shut down clinics using those products. But there are other products that undergo processing that many physicians and manufacturers argue constitutes minimal manipulation. And these tissues are cleared, potentially fragmented or particulated to make them more suitable for injection, preserved using methods like cryopreservation or liophalization and packaged. Dr. Deb Muth 24:54But the cells are not cultured or expanded in the laboratory. The FDA has issued guidance suggesting that many of these processing steps constitute more than manipul minimal manipulation. But many physicians, particularly those who specialized in regenerative medicine for years, disagree with that interpretation and they believe that the processing qualifies as minimal manipulation and that the product should fall under section 361 when used for homologous purposes. Dr. Deb Muth 25:24Is there regulatory debate? Absolutely. The FDA and some clinicians have different interpretations of what constitutes minimal manipulation. But here’s the practical reality. There are hundreds of well-trained, bore certified physicians across the United States offering these therapies every single day. Dr. Deb Muth 25:42They’re doing so based on their understanding of the regulations, their clinical experience, their commitment to patient safety, and their belief that these therapies can help people who have exhausted conventional options. The FDA’s enforcement priorities have focused primarily on the most problematic cases. Clin clinics making blatant disease cure claims, products with documented safety issues, clear cases of cellular expansion and culture, or clinics operating with no medical oversight. Dr. Deb Muth 26:15Reputable regenerative medicine physicians are using products from companies that provide comprehensive documentation of their processing methods. third-party sterility testing, certificates of analysis showing bioactive content, and quality control measures that meet or exceed industry standards. Now, let me be very clear about something. Dr. Deb Muth 26:36Quality matters enormously. Not all stem cells and exoome products are created equal. Research by Burger and colleagues published in the Orthopedic Journal of Sports Medicine in 2021 analyzed 12 commercially available stem cell products and found that many contained zero viable cells, high levels of bacteria, endotoxins and inconsistent growth factor concentrations. Dr. Deb Muth 27:01This is why the company providing these biologic matters tremendously. You want products from manufacturers who provide transport documentation in sourcing and processing. Conduct third-party testing and sterility and potency. Offer certificates of analysis for each batch. Use standardized validated processing protocols. Dr. Deb Muth 27:24Have quality control measures that ensure consistency and don’t make outrageous cure claims or promise. The best regenerative medicine physician carefully vet their suppliers. They don’t use products from companies making unrealistic promises. They use products from manufacturers who are transparent, scientifically rigorous, and committed to quality. Dr. Deb Muth 27:46Now, you specifically ask about homologous use and collagen defects. So, let me address this directly for you. Under the FDA guidance, homologous use means the tissue performs the same basic function in the recipient as in the donor. So for connective tissue, tendons, ligaments, cartilage, fascia, all of that which are collagenrich structures using MSC’s or their derivatives could be considered homologous use. Dr. Deb Muth 28:17MSC’s in their native environment provide structural support to produce extracellular matrix including collagen. Using them to support healing in damaged collagen rich tissues like arthritic joints, torn tendons or degenerative ligaments is arguably the same basic function. So using exoomes derived from MSC’s to support collagen synthesis reduce inflammation and promote tissue healing in the same structures. Dr. Deb Muth 28:46Many practitioners argue this also qualifies as homologous use because you’re supporting the structure and function that MSC’s would naturally support. So here’s the bottom line on the regulatory reality. Regenerative medicine is available in the United States. It’s being offered by highly trained physicians in integrative and regenerative medicine clinics across the country. Dr. Deb Muth 29:11Some therapies are offered in FDA registered clinics and some are offered in observational studies. Some are offered in clinical practice under physician discretion, informed consent, and careful attention to safety. The regulatory landscape is evolving. There are ongoing discussions both federally and state levels about creating clearer pathways for these therapies. Dr. Deb Muth 29:32So, if you choose to go down this road, you want to work with physicians who understand the regulations, who use quality products from reputable manufacturers with rigorous testing and documentation, who are transparent about what they’re using and why, who discuss the current regulatory landscape honestly with you, and who prioritize your safety and truly informed consent above all else. Dr. Deb Muth 29:55This is not a lawless wild wild west. But it is also not as simple as everything is legal and unavailable. It’s a nuanced landscape that requires ethical knowledge. And these practitioners that have this knowledge have got to provide informed patients who understand both the potential benefits and the current regulatory context. Dr. Deb Muth 30:17So let’s have some fun here. Let’s talk about what really matters to you that are listening and that’s what conditions are being supported with these therapies. What does the research show and what are clinicians seeing in actual practice with patients? Because here’s what’s really important. We have both published research evidence and extensive clinical experience. Dr. Deb Muth 30:38And when the two align, that’s when we can feel confident and comfortable about using these approaches. So, let’s start where we have the most substantial evidence. joint health and muscularkeeletal conditions. For arthritis, we have good data. A systemic review by Tan and colleagues published in arthritis research and therapy in 2021 analyzed 20 randomized controlled trials in MSC therapy for knee osteoarthritis. Dr. Deb Muth 31:05They found significant improvements in pain and function particularly in mild to moderate disease. What’s really interesting is when researchers start analyzing whether it was the cells themselves or their secreted factors doing the work. They found that exoomeenriched preparations showed similar benefits to whole cell therapy. Dr. Deb Muth 31:26Now towen colleagues in the biioaterials paper from 2017 demonstrated that MSC derived exoomes could promote cartilage matrix synthesize and reduce inflammation markers. The exoomes carried microarnas that told cartilage cells to make more collagen and proteoglycans, the building blocks of healthy cartilage. Dr. Deb Muth 31:49In clinical practice, physicians are seeing patients with knee, hip, shoulder, and spinal arthritis, experiencing reduced pain, improved function, better motility, and in some cases, measurable improvements in their tissue. I want to share a story here with you because back in 2006, my husband was injured at work. Some of you might have heard me tell this story before. Dr. Deb Muth 32:11Um, he broke two discs in his back and underwent surgery very early on when we started using stem cells. They had put cages and plates in and they used MSC’s to put inside the cage to create a hardened bone so that he could have a fusion and hopefully not have any pain. At the time, what the physician didn’t realize or mistakenly did was he did not put any human bone mixed with these dead cadaavver bone MSC’s. Dr. Deb Muth 32:42And so the MSC’s never grew. They didn’t have anything to grow by. So the plates and the screws just kind of went back and forth for six months before he could see another physician that would look at him differently and understand what actually happened. That was very early on. Today we know so much more than we did before. Dr. Deb Muth 33:01Fast forward to 2014 when my husband was having problems and he couldn’t feel his legs, he couldn’t feel his feet. We decided to undergo uh exoo and stem cell therapy again and we saw a physician in Florida who harvested cells from his bone marrow and his blood and his fat and mixed that all together and then put that back into the back. Dr. Deb Muth 33:27and he had tremendous benefit from it. So, I tell this story because I want you to see the trajectory of how long this has been going on that we’ve been using this and we’re learning as we’re going and things are changing rapidly in this in this world. And so, what we know today and what I’m teaching you today may very well change in a month or six months or a year from now, but we have the foundation at least to understand what is helpful, what is not right now. Dr. Deb Muth 33:54But just be aware that if you’re embarking on exoome or stem cell therapy or MSC’s that you understand that this terrain is going to change. So back to my conversation about what other things can we treat? Well, we can treat tendon and ligament injuries, chronic tennis elbow, Achilles tendonopathy, rotator cuff tears, chronic planter fasciitis. Dr. Deb Muth 34:17These were researched by PA and colleagues in the American Journal of Sports Medicine in 2017 and it showed that bone marrow concentrate injections resulted in improved pain and function compared to steroid injections. Now this mechanism appears to be enhanced collagen remodeling and reduced chronic inflammation. Dr. Deb Muth 34:39These are structural collagenrich tissues using MSC’s or their derivatives for structural support which makes biological sense. It’s homologous use. It’s similar. So clinically we’re seeing athletes, active adults and people with chronic pain who failed physically um failed physical therapy, failed conservative treatments finding relief in this functional uh improvement in this functional world that we live in today. Dr. Deb Muth 35:07So, I want to be clear about what we’re doing here for joint and muscularkeeletal issues. We’re not growing completely new cartilage from scratch or severely destroyed joints. We’re not magically regenerating tissues that’s been gone for decades. That’s not possible here. What you’re doing when you’re using MSSE’s and exoomes is supporting the body’s natural ability to repair, reducing inflam inflammation and damage, and we’re driving progressive degeneration uh or we’re stopping the progressive degeneration. By reducing the Dr. Deb Muth 35:41inflammatory damage, we’re stimulating resonant stem cells that have been dormant. We’re improving blood flow and uh uh oxygen to the tissues like cartilage and tendons. and we’re organizing the body to start creating its own quality collagen as it heals. So, it’s a regenerative support, not a tissue replacement. Dr. Deb Muth 36:07But for many people, this support is lifechanging. So, let’s talk about autoimmune disorders now because this is one of the most exciting and unrecognized applications. autoimmune conditions like rheumatoid arthritis, lupus, MS, Crohn’s disease, ulcerative colitis, Hashimoto’s, they all involve the immune system and the immune system is deregulated. Dr. Deb Muth 36:30And so basically your immune system is seeing this tissue as foreign and it’s attacking it. These MSC’s and their exoomes have profound immune modulatory properties. They don’t suppress the immune system like steroids or imunosuppressive drugs. They modulate it helping to restore balance. So for rheumatoid arthritis, research by Weang and colleagues in stem cells translational medicine in 2016 showed that MSC derived exoomes could shift the balance of immune cells, reducing pro-inflammatory TH7 cells that drive joint disruption uh and increase Dr. Deb Muth 37:08regulatory TE-C cells that maintain immune tolerance. So for MS, a clinical trial by Kasus and colleagues published in archives of neurology back in 2010 evaluated autotogus MSC therapy and MS patients and they found evidence of reduced disease activity, improved neurological function and decreased inflammatory uh lesions on MRI scans. Dr. Deb Muth 37:34The proposed mechanism is MSC’s and their exoomes reduce inflammatory cytoine production promote regulatory imu immune populations support remination of damaged nerves that is rebuilding the protective coating around the nerve fibers and it reduces bloodb brain barrier permeability which prevents immune cells from attacking their brain and spinal cord. Dr. Deb Muth 38:02And so for inflammatory bowel disease, the research by Barnholm uh sorry Barnhorn and colleagues in gut in 2020 showed that MS cell MSC derived extracellular vesicles could support mucosal healing and reduce inflammation in the gut lining. They appeared to restore intestinal barrier function, healing that leaky gut and modulating local immune responses. Dr. Deb Muth 38:30So in clinical practice, physicians are seeing patients with autoimmune conditions, experiencing reduced disease flares, decreasing the need for imunosuppressive medications, improving energy and quality of life, and in some cases extending periods of remission. But here’s what I want you to understand. Dr. Deb Muth 38:52When you see these therapies for autoimmune conditions, we are supporting immune regulation and reducing inflammatory damage. We are not treating or curing the disease in a conventional sense. These therapies work best as part of a comprehensive functional medicine approach that also addresses gut health because 70% of your immune system lives in your gut and environmental triggers like mold, heavy metals, chemical toxins that can drive autoimmune responses, chronic infections that can trigger immune disregulation, stress and nervous system imbalance. And Dr. Deb Muth 39:29these nutritional deficiencies are necessary to help improve the immune function. So regenerative therapy without addressing root causes is like bailing water out of your boat without plugging the hole. You might get temporary relief, but the underlying problem still remains. So let’s talk about neurological conditions. Dr. Deb Muth 39:52And this is where the science gets truly fascinating. for traumatic brain injury and concussion. Research by Zang and colleagues in the Journal of Neurot Trauma in 2015 showed that MSC derived exoomes could reduce brain inflammation, promote neuroplasticity, that’s the brain’s ability to rewire itself and improve cognitive outcomes in animal models. Dr. Deb Muth 40:17The exoomes crossed the bloodb brain barrier, delivered neuroprotective proteins and microRNAs. They reduced inflammation, supported mitochondrial function in injured neurons and promoted both new blood vessels from new blood formation and neurogenesis and the birth of new neurons occurred. Neurological recovery requires a multi-systematic approach. Dr. Deb Muth 40:42Exoomes may support neural repair, but they work best combined with hormone optimization, growth hormone, testosterone, thyroid, pregnnolone, mitochondrial support compounds like NAD, CoQ10, PQQ, carnitine, all of those things that we use traditionally in functional medicine. Now for stroke recovery, there was research by Zinn and colleagues in the journal of extracellular vesicles that showed MSC derived exoomes reduced the size of brain damage and improved neurological recovery in animal models. There was a Dr. Deb Muth 41:19Parkinson’s disease study done by Kimoji and colleagues in the movement disorders in 2018 that suggested that MSSE derived exoomes could support dopamineergic neuron survival and those are the cells that die in Parkinson’s and it can help to reduce neuroinflammation. Clinically, physicians are seeing improvements in patients with postconussion syndrome, chronic traumatic brain injury, early stage cognitive decline, and other neurodeenerative conditions. Dr. Deb Muth 41:52These are not cures, but meaningful improvements in cognitive function, mood, energy, and quality of life. Now, let’s talk about autism spectrum disorder very carefully here because this is a very sensitive but very important topic for families. There have been several clinical trials that have explored MSC therapy for autism. Dr. Deb Muth 42:16Liv and colleagues published research in stem cell translational medicine in 2013 showing improvements in social interaction, communication, and behavioral symptoms in children with ASD who received cord blood MSC’s. Dawson and colleagues in 2017 conducted randomized trial autotogus cord blood infusion and found modest improvements in social communication particularly in children with higher baseline immune dysregulation. Dr. Deb Muth 42:47The proposed mechanisms for modulation of neuroinflammation support the mitochondrial function because many children with autism show evidence of mitochondrial dysfunction, reduction of oxidative stress, improvement in gut brain access dysfunction and modulation of immune dysregulation. In clinical practice, some physicians are seeing improvements in some children, better eye contact, increased language development, reduced sensory sensitivities, improved social engagement, but responses vary significantly, and we cannot predict which children will benefit most. So for Dr. Deb Muth 43:26families considering regenerative approaches for autism, these therapies are supporting the body’s healing mechanisms, reducing neuroinflammation, supporting cellular energy production, modulating immune function. These should only be considered as part of a comprehensive biomedical approach that includes dietary interventions to address food sensitivities, support gut health, environmental toxin removal, particularly heavy metals and chemical exposures, gut healing protocols with targeted probiotics and nutrients, Dr. Deb Muth 44:00metabolic testing and targeted supplementation, and evidence-based on behavioral and developmental therapies. These therapies should only be pursued with practitioners who are honest about what we know and what we don’t know and who follow rigorous safety protocols who never promise cures and who view regenerative medicine as a tool in the comprehensive healing strategy, not a standalone miracle. Dr. Deb Muth 44:26Not only that, these therapies will most likely need to be given several times over the course of this person’s lifetime, possibly even on an annual basis. And this is really important because it is not a oneandone. It is not a one-sizefits-all, and it needs to be looked at as a long-term option for working with autism. So, since we’re looking at stem cells versus exoomes, living cells, with stem cell therapy, you’re receiving living cells that can survive in your body for days to weeks. Dr. Deb Muth 45:02With exoome therapy, there are no living cells, just biological messages they would have sent. So, replication stem cells can potentially replicate. Although therapeutically this happens minimally, exoomes cannot replicate. They deliver the cargo and then they are cleared by your body. With stem cells, it’s primarily paracrine signaling. Dr. Deb Muth 45:28They’re coaching your cells to heal. With exoomes, it’s pure signaling, pure reprogramming your cells without any cellular component. Stem cells as we talked about can be autotogus from your own bone fat, blood or um bone marrow or allergenic from umbilical cord tissue or Wharton’s jelly. Dr. Deb Muth 45:50Exoomes are typically derived from cultured MSC’s often from umbilical cord or bone marrow sources and both can be given by local injection for targeted treatment of joints and tissues and exoomes can be given intravenously for whole body systemic support. both have um low immun immunogicity. I can’t say that word today. Dr. Deb Muth 46:17But exoomes have even lower risk since they contain no cellular material. Now, it’s absolutely critical for you to understand that there are massive quality differences. We’ve talked about this earlier. I want you to be very aware of this and have a conversation with any of the practitioners that you’re considering undergoing this treatment with. Dr. Deb Muth 46:37Here is where it matters more than anything when you’re considering regenerative medicine, the quality of the products and the expertise of the practitioner. Because the reality is not all regenerative medicine products are created equal. We all know that when we take different supplements and not all practitioners understand these therapies at the same depth. Dr. Deb Muth 46:58You want to look for practitioners that are board certified or have some kind of specialized regenerative medicine training. You want to know their clinical experience. How much have they done these procedures? How long have they done this? You want honest communication about the evidence and the limitations in this. Dr. Deb Muth 47:17You want a comprehensive functional medicine approach to go along with these therapies. And you want somebody that’s transparent about their informed consent and their regulatory status. If you have people that are uh claiming that they can cure disease or giving you guarantees, that is not that is not a good practitioner to work with. Dr. Deb Muth 47:37If you have high pressure sales tactics, you need to decide today limited supply for a week. These are marketing manipulations. It’s not medical care. You want to be cautious of extremely low prices because quality regenerative products are expensive to source, process, and test. and store. And if somebody’s offering stem cells or exoomes for a few hundred dollars, seriously, you need to question the quality, the safety, and where they got this from. Dr. Deb Muth 48:09So before undergoing any regenerative therapy, make sure you’re having a very, very lengthy conversation with the person and so you truly understand exactly what you’re getting, how it’s going to be delivered, and what they’re going to do. If there’s one thing I want you to take away from today is that your body has remarkable capacity to heal when given the right biological signals and the right environment. Dr. Deb Muth 48:35Stem cells and exoomes are powerful tools for providing biological signaling that can reduce inflammation, modulate immune function, support tissue repair, and restore cellular communication that’s been disrupted by chronic disease and inflammation. These therapies are available in the United States through trained physicians working in FDA registered trials, observational studies, and clinical practice, and using quality products from manufacturers with rigorous testing and quality control. Dr. Deb Muth 49:04So before you invest in regenerative medicine, do your homework. Ask detailed questions about product quality and source. Verify the products come from reputable manufacturers with certificates of analysis, third-party testing. Work with experienced practitioners. And remember, no injection, no infusion, no biologic can overcome ongoing toxic exposure, chronic stress, poor nutrition, gut dysfunction, and inadequate sleep. Dr. Deb Muth 49:34True healing requires your body and you to actively participate in this healing. If you are unwilling to address the root causes and change the lifestyle factors that disrupted your health in the first place, the biologics can amplify your healing signals, but you have to create the internal environment where healing can actually happen. Dr. Deb Muth 49:56So, I hope this episode has helped you understand regenerative medicine more clearly. Share it with somebody who’s looking for healing beyond the conventional approaches. And until next time, this has been Let’s Talk Wellness Now. Have a blessed day. >> Welcome to Let’s Talk Wellness Now, where we bring expert insights directly to you. Dr. Deb Muth 50:16Please note that the views and information shared by our guests are their own and do not necessarily reflect those of Let’s Talk Wellness Now, its management, or our partners. Each affiliate, sponsor, and partner is an independent entity with its own perspectives. Today’s content is provided forformational and educational purposes only and should not be considered specific advice, whether financial, medical, or legal. Dr. Deb Muth 50:41While we strive to present accurate and useful information, we cannot guarantee its completeness or relevance to your unique circumstances. We encourage you to consult with a qualified professional to address your individual needs. Your use of information from this broadcast is entirely at your own risk. Dr. Deb Muth 51:00By continuing to listen, you agree to indemnify and hold Let’s Talk Wellness Now and its associates harmless from any claims or damages arising from the use of this content. We may update this disclaimer at any time, and changes will take effect immediately upon posting or broadcast. Thank you for tuning in. We hope you find this episode both insightful and thought-provoking. Listener discretion is advised.The post Episode 265 – The Future of Healing: How Exosomes Re-Educate Your Body to Heal Itself first appeared on Let's Talk Wellness Now.

Mickey Trescott, MSc, is an author, nutrition professional, and one of the pioneers who helped build the Autoimmune Protocol community from the ground up. Her brand-new book, The New Autoimmune Protocol, is the first major update to AIP in over a decade—and this conversation is one I've been wanting to have for a long time. If you've ever been curious about AIP, intimidated by it, or tried it and struggled to sustain it, this episode is for you. We get into what's changed about AIP, what the latest AIP research supports, and how to approach this therapeutic tool in a way that's flexible, personalized, and built for real life. In this episode: Why AIP needed to evolve What the research says about AIP The biggest misconceptions about AIP Core vs. Modified AIP Reintroductions and personalization The essential Transition Phase Common AIP pitfalls and mistakes How AIP can help people with Hashimoto's and autoimmune thyroid disease Practical tips for getting started

GET HEIRLOOM SEEDS & NON GMO SURVIVAL FOOD HERE: https://heavensharvest.com/wam USE Code WAM to save 25% plus free shipping! Pledge here! Just a dollar a month can help us alive! https://www.patreon.com/user?u=2652072&ty=h&u=2652072 EXCLUSIVE replays of hour plus long live shows are available here at $5 a month or more! BUY GOLD HERE: https://firstnationalbullion.com/schedule-consult/ Avoid CBDCs! GET 10% OFF ON SHILAJIT FROM DR. KAUFMAN WHEN YOU USE CODE WAM10 HERE: https://medauthentica.com/discount/WAM10?redirect=/products/authentica-shilajit%3Fsca_ref=10867124.wrNV3jkYSaMg9 HELP SUPPORT US AS WE DOCUMENT HISTORY HERE: https://gogetfunding.com/help-keep-wam-alive/# Josh Sigurdson reports on the massive supply chain crisis effecting essentially the entire world as shipping giants Maersk, Hapag-Lloyd, MSC, CMA and CGM create a new shipping route by-passing the Strait of Hormuz by dropping off boat loads, driving across the country and then loading everything back on to other boats. Costs are about to skyrocket but it's far worse than just costs. The ability to obtain food, fertilizer and oil are about to collapse in a way never before seen in modern history. They are manufacturing a famine to force people into a ration-based digital ID system complete with social credit. Costs of potatoes alone went from 2.5 Euros to 18.5 Euros per 100kgs in a single month due to fertilizer shortages which farmers have been warning about for quite some time. Sulfuric acid is at a major deficit currently which leads to shortages of fertilizer as well as tools needed for mining and manufacturing across the board. This alone can cause a famine. On top of this however, we were already seeing an attack internationally on farmland as well as 73 year shortages of cattle head. Farm bankruptcies are up 46%. 70% of farmers cannot afford fertilizers. Diesel prices are up 60% in a year. President Trump recently said in an interview with Sean Hannity that high gas prices are the price we pay for Iran not having nuclear weapons. This is insanity. Meanwhile, engine oil is scarce and data centers are being built everywhere to complicate matters more. Water shortages will be a major problem in cities near data centers as people like Mike Adams has warned about on Natural News. This will hurt farms and industry while the data centers collect everyone's information in a massive surveillance database. They're creating a Hive Mind to help "solve" the very shortages they created in the first place. It just so happens that back in July of 2025, the DOE (Department of Energy) warned that we will see a 100x increase in blackout risks by 2030. That year isn't a coincidence. The United Nations planned for this years ago. It also just so happens that government run grocery stores are being established in New York and proposed in California and cities like Chicago. In the UK where they are pushing forward a digital ID mandate, they are attempting to police what foods you buy. This is one of the many steps towards the digital gulag system to come. From banks to energy and food, this system which the WEF has pushed for years is being adopted, quickly. It's up to you to actually take the warning and do something about it or sit there on your hands awaiting you dark fate. Stay tuned for more from WAM! GET YOUR WAV WATCH HERE: https://buy.wavwatch.com/WAM Use Code WAM to save $100 and purchase amazing healing frequency technology! Get Your SUPER-SUPPLIMENTS HERE: https://vni.life/wam Use Code WAM15 & Save 15%! Life changing formulas you can't find anywhere else! Get local, healthy, pasture raised meat delivered to your door here: https://wildpastures.com/promos/save-20-for-life/bonus15?oid=6&affid=321 USE THE LINK & get 20% off for life and $15 off your first box! DITCH YOUR DOCTOR! https://www.livelongerformula.com/wam Get a natural health practitioner and work with Christian Yordanov! Mention WAM and get a FREE masterclass! You will ALSO get a FREE metabolic function assessment! GET YOUR APRICOT SEEDS at the life-saving Richardson Nutritional Center HERE: https://rncstore.com/r?id=bg8qc1 Use code JOSH to save money! PayPal: ancientwonderstelevision@gmail.com FIND OUR CoinTree page here: https://cointr.ee/joshsigurdson PURCHASE MERECHANDISE HERE: https://world-alternative-media.creator-spring.com/ JOIN US on SubscribeStar here: https://www.subscribestar.com/world-alternative-media For subscriber only content! BITCOIN ADDRESS: 18d1WEnYYhBRgZVbeyLr6UfiJhrQygcgNU World Alternative Media 2026

Pain is not just tissue damage - but it's also just not in your brain. In this episode, we're joined by Taylor Kruse of Kruse Elite. We discuss the neuroscience of pain and movement, including how the brain processes pain, the role of the vestibular system, and how we can think about non-injury pain for runners. Bonus: you will also learn why motion sickness happens!Thank you to our sponsors:✨Title Nine: Comfortable sports bras that actually fit, from a women-owned company. Use code RUNTOTHEFINISH for free shipping at https://runtothefinish.com/title-nine/In this episode, you'll hear our takes on:✅ The role of the brain in perceiving pain✅ The difference between overuse injury pain and perceived threat pain✅ How stress plays a role in perceived pain✅ How to train your nervous system to process movement and sensations✅ Why you get motion sickness✅ Why multi-directional training is valuable for runnersConnect with our guest:Kruse Elite on Youtube: https://www.youtube.com/@KRUSEELITEKruse Elite on Instagram: https://www.instagram.com/kruseelite/Tread Lightly Running is hosted and researched by Amanda Brooks and Laura Norris, MSc. Production, show notes, and graphics by Laura Norris.Let's stay connected:➡️ Tread Lightly Running Podcast on Instagram: https://www.instagram.com/treadlightlyrunning/➡️ Laura Norris Running on Instagram: https://www.instagram.com/lauranorrisrunning/➡️ Subscribe for weekly evidence-based newsletters, straight to your inbox, on https://lauranorrisrunning.substack.com/➡️ Run to the Finish on Instagram: https://www.instagram.com/runtothefinish/?hl=en➡️ Thousands of running gear reviews and training guides: https://runtothefinish.com/

Check out MSC online courses below: https://www.modernsoccercoach.com/analysis What happens when coaches try to copy elite professional environments without understanding the players actually in front of them? John's coached across multiple levels of the game, including more than a decade in Major League Soccer, over fourteen years as a collegiate head coach, and extensive work as a U.S. Soccer coach educator. But what makes this conversation really fascinating is the work he's now doing away from the touchline. In this episode of the Modern Soccer Coach Podcast, Gary Curneen sits down with longtime coach educator and former professional coach John Murphy for a deep discussion on modern coaching, high school soccer, player development, coach education, and the changing realities of working with today's athletes. The conversation explores: Why coaching feels harder today The danger of copying pro environments High school soccer in America Coach education and player understanding Periodization and modern methodology Parenting culture in youth sports American vs European coaching culture The importance of context, empathy, and communication Why coaches must “coach the players they have” John Murphy also discusses his doctoral research examining modern coach education and how coaches can better support players beyond simply tactics and performance. This is one of the most honest and thought-provoking coaching conversations we've had on the channel.

You can register for Fetch Encore here today! On this week's episode of The Vet Blast Podcast presented by dvm360,  host Adam Christman, DVM, MBA, and Emmanuel Fontaine DVM, MSc, PhD, DECAR, discuss the importance of microbiome development in neonatal puppies and kittens. Throughout the episode, the duo unpacks how puppies and kittens inherit their mother's microbiome, why C-sections and weaning can disrupt that process,  how colostrum, nutrition, and smart hygiene can set the stage for lifelong health, and more. 

When Panama's Supreme Court ruled that Hong Kong-based conglomerate CK Hutchison's operation of two ports on either side of the Panama Canal was unconstitutional, President Jose Raul Mulina said at the time that he wasn't too concerned about China retaliating. Now, several months later, Mulina and other Panamanian officials are becoming increasingly concerned that this is precisely what's happening after China detained dozens of Panamanian-flagged vessels or "inspections." Separately, China called on the two shipping companies, Maersk and MSC, slated to take over operations of the Panamanian ports vacated by CK Hutchison, to reconsider — insinuating there could be severe consequences if they don't comply. Pedro Armada, managing partner at Armada Risk Consulting, is following the events closely from Panama City and joins Eric to discuss the increasingly difficult position the government finds itself in between the U.S. and an increasingly assertive China.

Thomas Lamb is an internationally recognized entrepreneur and executive in the resource sector. He's currently the CEO of Myriad Uranium Corp and is leading the advancement of one of the most historically significant uranium districts in the United States. The Copper Mountain Project in Wyoming encompasses over 18,000 acres and is underlain by an estimated uranium endowment exceeding 600 million pounds. He's also the CEO of J2 Metals Inc., overseeing a diversified exploration portfolio spanning three jurisdictions in Mexico, Canada, and Alaska. His work has spanned uranium, gold, cobalt, and critical minerals across North America, Mexico, Russia, and Africa. He has a MSc from London Business School and law degree from the University of British Columbia. This podcast is for informational purposes only. Guest speakers and their firms are not affiliated with or endorsed by PAS or Guardian. This material contains the current opinions of the speakers but not necessarily those of PAS, Guardian or its subsidiaries and such opinions are subject to change without notice. None of the organizations mentioned in this podcast have any affiliation with Guardian or PAS. Bryan Kuderna is a Registered Representative and Financial Advisor of Park Avenue Securities LLC (PAS). OSJ: 50 Tice Blvd. Woodcliff Lake, NJ 07677 (973)244-4420. Securities products and advisory services offered through PAS, member FINRA, SIPC. Financial Representative of The Guardian Life Insurance Company of America® (Guardian), New York, NY. PAS is a wholly owned subsidiary of Guardian. Kuderna Financial Team is not an affiliate or subsidiary of PAS or Guardian. CA Insurance License #OK04194    #8933524.1 exp. 5/28

Is bib-sharing wrong? Should downhill races count as a PR? Are AI running apps the future of the sport, or setting up runners for injury? In this episode, we have a nuanced discussion on many of the gray areas of sportsmanship and running culture.✨Title Nine: Comfortable sports bras that actually fit, from a women-owned company. Use code RUNTOTHEFINISH for free shipping at https://runtothefinish.com/title-nine/✨ Tailwind: Complete sport nutrition made simple, including hydration mixes, high-carb sport drinks, endurance fuel, and recovery mixes. Use code TREADLIGHTLY20 at https://tailwindnutrition.com/TREADLIGHTLY for 20% off your first purpose.In this episode, you'll hear our takes on:✅ Bib sharing and banditing✅ AI coaching apps✅ What counts as a PR?✅ Running races while injured✅ The ever-changing Boston Qualifying standardsTread Lightly Running is hosted and researched by Amanda Brooks and Laura Norris, MSc. Production, show notes, and graphics by Laura Norris.Let's stay connected:➡️ Tread Lightly Running Podcast on Instagram: https://www.instagram.com/treadlightlyrunning/➡️ Laura Norris Running on Instagram: https://www.instagram.com/lauranorrisrunning/➡️ Subscribe for weekly evidence-based newsletters, straight to your inbox, on https://lauranorrisrunning.substack.com/➡️ Run to the Finish on Instagram: https://www.instagram.com/runtothefinish/?hl=en➡️ Thousands of running gear reviews and training guides: https://runtothefinish.com/

Kaz has a PhD in human behaviour and MSc in Sport and Exercise Psychology, and has studied our power to perform when faced with adversity. Passionate about helping people believe in themselves she explores what is it about our fears, courage, resilience, and mindset, that drives us to succeed or sabotages us? And Kaz loves to run far.   Her trail running journey started in Chamonix, France with the Mont Blanc Marathon and UTMB races. Favorite adventures include Tahoe 200 (3rd F), Moab 240 (2nd F), Ouray 100 (1st F), Tot Dret, Italy (3rd F) and Across the Years (420 miles in 10 days – 3rd F), plus successfully completing 1 crazy loop of The Barkley Marathons, and most recently finishing Last Annual Vol State, a 500K continuous and self-supported race across Tennessee. Follow the new pod insta @trailrunningwomenpod !! Find Kaz @mountainkaz