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5 episodes with wellcome trust centre
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2 episodes with wellcome trust centre
2 episodes with wellcome trust centre
2 episodes with wellcome trust centre
2 episodes with wellcome trust centre
2 episodes with wellcome trust centre
2 episodes with wellcome trust centre
Talking with Dr. Julie Faitg was a powerful reminder of just how much we're discovering about mitochondria and aging. When you pair an elite mitochondrial scientist with a breakthrough nutrient like Urolithin A, the insights go beyond what you'd expect. Julie gives us this incredible look into how we can actually change the course of aging at the cellular level. This conversation made me rethink what we know about supporting long-term health and resilience, and I think it will do the same for you. It's one of those big-picture, eye-opening conversations that I can't wait for you to hear. ~DrKF CHECK OUT THE SHOW NOTES AT https://www.drkarafitzgerald.com/fxmed-podcast/ for a full list of links and resources. GUEST DETAILS Dr. Julie Faitg, PhD Email: jfaitg@timeline.com Dr. Julie Faitg is a leading expert in mitochondrial research, with over nine years of experience focusing on muscle and brain biology, and recently expanding her expertise to include skin health. Holding a PhD in Translational and Clinical Research from the Wellcome Trust Centre for Mitochondrial Research, she collaborates with renowned scientists worldwide, including Nobel laureate Eric Kandel and mitochondrial experts. Currently, Dr. Faitg serves as the Senior Translational Scientist and Regulatory Affairs Lead at Timeline, where she makes significant contributions to research and development across various organ systems in the field of mitochondrial biology. THANKS TO OUR SPONSOR Timeline: https://tinyurl.com/4x832df9 SPECIAL OFFER: Timeline is offering a 10% discount on all of their products to New Frontiers listeners. Head over to https://tinyurl.com/4x832df9 and use code KaraSkin at checkout. CONNECT WITH DrKF: Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You Group Program: https://tinyurl.com/4hvusavw Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw
This event was hosted by Cambridge Family Law Centre (CFL) on 7 March 2024. Speakers: Professor Laura Lundy (Queen’s University Belfast), Professor Anne Barlow (University of Exeter) & Dr Jan Ewing (University of Cambridge) When parents separate, children have the right to a voice in the decision-making per their article 12, UNCRC rights. However, evidence shows that this right is rarely upheld in England and Wales. Professor Lundy has developed the ‘Lundy Model of Child Participation’ (‘the Lundy Model’), a core set of rights-based principles to ensure young people can participate meaningfully in decision-making. The model is core to the Irish National Framework on Child and Youth Participation. It has been adopted internationally, by the European Commission, World Health Organisation, World Vision and UNICEF. Professor Lundy presents the Lundy Model and Professor Barlow and Dr Ewing presents the findings of empirical research from the Wellcome Trust Centre-funded, ‘HeaRT Project’ to consider the extent to which child-inclusive mediation as currently practised in England and Wales is compliant with their article 12 rights and the mental health and well-being benefits to young people when they are given space, voice, audience and influence per the Lundy Model in child-inclusive mediation. For more about CFL see: https://www.family.law.cam.ac.uk/ This entry provides an audio source for iTunes.
This event was hosted by Cambridge Family Law Centre (CFL) on 7 March 2024. Speakers: Professor Laura Lundy (Queen’s University Belfast), Professor Anne Barlow (University of Exeter) & Dr Jan Ewing (University of Cambridge) When parents separate, children have the right to a voice in the decision-making per their article 12, UNCRC rights. However, evidence shows that this right is rarely upheld in England and Wales. Professor Lundy has developed the ‘Lundy Model of Child Participation’ (‘the Lundy Model’), a core set of rights-based principles to ensure young people can participate meaningfully in decision-making. The model is core to the Irish National Framework on Child and Youth Participation. It has been adopted internationally, by the European Commission, World Health Organisation, World Vision and UNICEF. Professor Lundy presents the Lundy Model and Professor Barlow and Dr Ewing presents the findings of empirical research from the Wellcome Trust Centre-funded, ‘HeaRT Project’ to consider the extent to which child-inclusive mediation as currently practised in England and Wales is compliant with their article 12 rights and the mental health and well-being benefits to young people when they are given space, voice, audience and influence per the Lundy Model in child-inclusive mediation. For more about CFL see: https://www.family.law.cam.ac.uk/ This entry provides an audio source for iTunes.
This event was hosted by Cambridge Family Law Centre (CFL) on 7 March 2024. Speakers: Professor Laura Lundy (Queen’s University Belfast), Professor Anne Barlow (University of Exeter) & Dr Jan Ewing (University of Cambridge) When parents separate, children have the right to a voice in the decision-making per their article 12, UNCRC rights. However, evidence shows that this right is rarely upheld in England and Wales. Professor Lundy has developed the ‘Lundy Model of Child Participation’ (‘the Lundy Model’), a core set of rights-based principles to ensure young people can participate meaningfully in decision-making. The model is core to the Irish National Framework on Child and Youth Participation. It has been adopted internationally, by the European Commission, World Health Organisation, World Vision and UNICEF. Professor Lundy presents the Lundy Model and Professor Barlow and Dr Ewing presents the findings of empirical research from the Wellcome Trust Centre-funded, ‘HeaRT Project’ to consider the extent to which child-inclusive mediation as currently practised in England and Wales is compliant with their article 12 rights and the mental health and well-being benefits to young people when they are given space, voice, audience and influence per the Lundy Model in child-inclusive mediation. For more about CFL see: https://www.family.law.cam.ac.uk/
This event was hosted by Cambridge Family Law Centre (CFL) on 7 March 2024. Speakers: Professor Laura Lundy (Queen’s University Belfast), Professor Anne Barlow (University of Exeter) & Dr Jan Ewing (University of Cambridge) When parents separate, children have the right to a voice in the decision-making per their article 12, UNCRC rights. However, evidence shows that this right is rarely upheld in England and Wales. Professor Lundy has developed the ‘Lundy Model of Child Participation’ (‘the Lundy Model’), a core set of rights-based principles to ensure young people can participate meaningfully in decision-making. The model is core to the Irish National Framework on Child and Youth Participation. It has been adopted internationally, by the European Commission, World Health Organisation, World Vision and UNICEF. Professor Lundy presents the Lundy Model and Professor Barlow and Dr Ewing presents the findings of empirical research from the Wellcome Trust Centre-funded, ‘HeaRT Project’ to consider the extent to which child-inclusive mediation as currently practised in England and Wales is compliant with their article 12 rights and the mental health and well-being benefits to young people when they are given space, voice, audience and influence per the Lundy Model in child-inclusive mediation. For more about CFL see: https://www.family.law.cam.ac.uk/ This entry provides an audio source for iTunes.
This event was hosted by Cambridge Family Law Centre (CFL) on 7 March 2024. Speakers: Professor Laura Lundy (Queen’s University Belfast), Professor Anne Barlow (University of Exeter) & Dr Jan Ewing (University of Cambridge) When parents separate, children have the right to a voice in the decision-making per their article 12, UNCRC rights. However, evidence shows that this right is rarely upheld in England and Wales. Professor Lundy has developed the ‘Lundy Model of Child Participation’ (‘the Lundy Model’), a core set of rights-based principles to ensure young people can participate meaningfully in decision-making. The model is core to the Irish National Framework on Child and Youth Participation. It has been adopted internationally, by the European Commission, World Health Organisation, World Vision and UNICEF. Professor Lundy presents the Lundy Model and Professor Barlow and Dr Ewing presents the findings of empirical research from the Wellcome Trust Centre-funded, ‘HeaRT Project’ to consider the extent to which child-inclusive mediation as currently practised in England and Wales is compliant with their article 12 rights and the mental health and well-being benefits to young people when they are given space, voice, audience and influence per the Lundy Model in child-inclusive mediation. For more about CFL see: https://www.family.law.cam.ac.uk/ This entry provides an audio source for iTunes.
This event was hosted by Cambridge Family Law Centre (CFL) on 7 March 2024. Speakers: Professor Laura Lundy (Queen’s University Belfast), Professor Anne Barlow (University of Exeter) & Dr Jan Ewing (University of Cambridge) When parents separate, children have the right to a voice in the decision-making per their article 12, UNCRC rights. However, evidence shows that this right is rarely upheld in England and Wales. Professor Lundy has developed the ‘Lundy Model of Child Participation’ (‘the Lundy Model’), a core set of rights-based principles to ensure young people can participate meaningfully in decision-making. The model is core to the Irish National Framework on Child and Youth Participation. It has been adopted internationally, by the European Commission, World Health Organisation, World Vision and UNICEF. Professor Lundy presents the Lundy Model and Professor Barlow and Dr Ewing presents the findings of empirical research from the Wellcome Trust Centre-funded, ‘HeaRT Project’ to consider the extent to which child-inclusive mediation as currently practised in England and Wales is compliant with their article 12 rights and the mental health and well-being benefits to young people when they are given space, voice, audience and influence per the Lundy Model in child-inclusive mediation. For more about CFL see: https://www.family.law.cam.ac.uk/
------------------Support the channel------------ Patreon: https://www.patreon.com/thedissenter PayPal: paypal.me/thedissenter PayPal Subscription 3 Dollars: https://tinyurl.com/ybn6bg9l PayPal Subscription 5 Dollars: https://tinyurl.com/ycmr9gpz PayPal Subscription 10 Dollars: https://tinyurl.com/y9r3fc9m PayPal Subscription 20 Dollars: https://tinyurl.com/y95uvkao ------------------Follow me on--------------------- Twitter: https://twitter.com/TheDissenterYT This show is sponsored by Enlites, Learning & Development done differently. Check the website here: http://enlites.com/ Dr. Uta Frith is Emeritus Professor of Cognitive Development at UCL Institute of Cognitive Neuroscience since 2006. She has been a Visiting Professor at the University of Aarhus at the Interacting Minds Centre from 2007 to 2015. She has been a Fellow at the Institute for Advanced Studies at the Central European University in Budapest (February - June 2014). Dr. Chris Frith is Emeritus Professor of Neuropsychology at the Wellcome Trust Centre for Neuroimaging at University College London, Visiting Professor at the Interacting Minds Centre at Aarhus University, Research Fellow at the Institute of Philosophy, and Quondam Fellow of All Souls College, Oxford. They are authors of “What Makes Us Social?”. In this episode, we focus on “What Makes Us Social?”. We start by discussing what social cognition is, and then go through topics like learning and imitation; emotions, our need to affiliate, and joint action; predicting other people's behavior; group identity; reputation; trust; mentalizing; how high-level cognitive processes interact with low-level cognitive processes; consciousness; collective problem-solving; and teaching, cumulative culture, and the role of culture in human cognition. Finally, we discuss how we can foster cooperation. -- A HUGE THANK YOU TO MY PATRONS/SUPPORTERS: PER HELGE LARSEN, JERRY MULLER, HANS FREDRIK SUNDE, BERNARDO SEIXAS, OLAF ALEX, ADAM KESSEL, MATTHEW WHITINGBIRD, ARNAUD WOLFF, TIM HOLLOSY, HENRIK AHLENIUS, JOHN CONNORS, FILIP FORS CONNOLLY, DAN DEMETRIOU, ROBERT WINDHAGER, RUI INACIO, ZOOP, MARCO NEVES, COLIN HOLBROOK, PHIL KAVANAGH, SAMUEL ANDREEFF, FRANCIS FORDE, TIAGO NUNES, FERGAL CUSSEN, HAL HERZOG, NUNO MACHADO, JONATHAN LEIBRANT, JOÃO LINHARES, STANTON T, SAMUEL CORREA, ERIK HAINES, MARK SMITH, JOÃO EIRA, TOM HUMMEL, SARDUS FRANCE, DAVID SLOAN WILSON, YACILA DEZA-ARAUJO, ROMAIN ROCH, DIEGO LONDOÑO CORREA, YANICK PUNTER, ADANER USMANI, CHARLOTTE BLEASE, NICOLE BARBARO, ADAM HUNT, PAWEL OSTASZEWSKI, NELLEKE BAK, GUY MADISON, GARY G HELLMANN, SAIMA AFZAL, ADRIAN JAEGGI, PAULO TOLENTINO, JOÃO BARBOSA, JULIAN PRICE, EDWARD HALL, HEDIN BRØNNER, DOUGLAS FRY, FRANCA BORTOLOTTI, GABRIEL PONS CORTÈS, URSULA LITZCKE, SCOTT, ZACHARY FISH, TIM DUFFY, SUNNY SMITH, JON WISMAN, DANIEL FRIEDMAN, WILLIAM BUCKNER, PAUL-GEORGE ARNAUD, LUKE GLOWACKI, GEORGIOS THEOPHANOUS, CHRIS WILLIAMSON, PETER WOLOSZYN, DAVID WILLIAMS, DIOGO COSTA, ANTON ERIKSSON, CHARLES MOREY, ALEX CHAU, AMAURI MARTÍNEZ, CORALIE CHEVALLIER, BANGALORE ATHEISTS, LARRY D. LEE JR., OLD HERRINGBONE, MICHAEL BAILEY, DAN SPERBER, ROBERT GRESSIS, IGOR N, JEFF MCMAHAN, JAKE ZUEHL, BARNABAS RADICS, MARK CAMPBELL, TOMAS DAUBNER, LUKE NISSEN, KIMBERLY JOHNSON, BENJAMIN GELBART, JESSICA NOWICKI, LINDA BRANDIN, NIKLAS CARLSSON, ISMAËL BENSLIMANE, GEORGE CHORIATIS, VALENTIN STEINMANN, PER KRAULIS, KATE VON GOELER, ALEXANDER HUBBARD, LIAM DUNAWAY, BR, MASOUD ALIMOHAMMADI, JONAS HERTNER, URSULA GOODENOUGH, GREGORY HASTINGS, DAVID PINSOF, SEAN NELSON, MIKE LAVIGNE, JOS KNECHT, ERIK ENGMAN, AND LUCY! A SPECIAL THANKS TO MY PRODUCERS, YZAR WEHBE, JIM FRANK, ŁUKASZ STAFINIAK, TOM VANEGDOM, BERNARD HUGUENEY, CURTIS DIXON, BENEDIKT MUELLER, THOMAS TRUMBLE, KATHRINE AND PATRICK TOBIN, JONCARLO MONTENEGRO, AL NICK ORTIZ, AND NICK GOLDEN! AND TO MY EXECUTIVE PRODUCERS, MATTHEW LAVENDER, SERGIU CODREANU, BOGDAN KANIVETS, AND ROSEY!
As sure as night follows day, we will face another pandemic, so how can we learn from the mistakes made during Covid-19, to ensure our response next time is not only more effective, but also more ethical? Today Mark and his guests Ilina Singh, James Wilson and John Prideaux dissect the British Government's approach during the Covid-19 pandemic and explore the failure to engage seriously with the ethical challenges the pandemic raised, comparing the British approach with those in the USA and China. And they debate how ethicists and ethical thinking could play a more central role in deciding how to respond to the next pandemic. With Catherine Joynson of the Nuffield Council on Bioethics. Produced in collaboration with the UK Pandemic Ethics Accelerator. Presented by Mark Honigsbaum @honigsbaum With: Catherine Joynson Associate Director, Nuffield Council on Bioethics www.nuffieldbioethics.org | @CathJoynson | @Nuffbioethics John Prideaux The political correspondent at the Economist. www.mediadirectory.economist.com/people/john-prideaux/ | https://www.economist.com/ | @JohnPrideaux | @TheEconomist Ilina Singh Professor of Neuroscience & Society at the University of Oxford and co-director at the Wellcome Trust Centre for Ethics and the Humanities. Principal Investigator on The UK Pandemic Ethics Accelerator, a collaborative project that brought UK ethics research expertise to bear on the multiple, ongoing ethical challenges present by Covid-19. https://www.psych.ox.ac.uk/team/ilina-singh | @OxPsychiatry James Wilson Professor of Philosophy and Co-Director of the Health Humanities Centre at UCL and co-investigator on the UK Pandemic Ethics Accelerator. www.ucl.ac.uk/philosophy/people/permanent-academic-staff/james-wilson | @jamesgswilson | @ucl Series Producer: Melissa FitzGerald @Melissafitzg Co-producer: Kate Jopling @katejopling Cover art by Patrick Blower www.blowercartoons.com Follow us on Twitter: @GoingViral_pod Follow us on Instagram: goingviral_thepodcast Blog: markhonigsbaum.substack.com This episode of Going Viral on trust in the pandemic, has been produced in collaboration with the UK Pandemic Ethics Accelerator. The Ethics Accelerator was funded by the UKRI Covid-19 research and innovation fund. https://ukpandemicethics.org/ | @PandemicEthics_ If you enjoy our podcast - please leave us a rating or review. Thank you!
WATCH: https://youtu.be/80jTPjAOzeY Chris Frith is Emeritus Professor of Neuropsychology at the Wellcome Trust Centre for Neuroimaging at University College London (UCL), Visiting Professor at the Interacting Minds Centre at Aarhus University, Research Fellow at the Institute of Philosophy and Quondam Fellow of All Souls College, Oxford. A Fellow of the Academy of Medical Sciences from 1999, Chris was elected a Fellow of the British Academy in 2008 and an Honorary Fellow of the British Science Association in 2010. He has won numerous medals and awards for his significant contributions to neuroscience, including the 2009 European Latsis Prize alongside his wife, the developmental psychologist Uta Frith — also a Fellow of the Royal Society. CONNECT: - Website: https://tevinnaidu.com - Instagram: https://instagram.com/drtevinnaidu - Facebook: https://facebook.com/drtevinnaidu - Twitter: https://twitter.com/drtevinnaidu - LinkedIn: https://linkedin.com/in/drtevinnaidu TIMESTAMPS: (0:00) - Introduction (0:36) - Consciousness definition (level vs content) (3:57) - Function of consciousness (evolution) (6:52) - Consciousness & AI (11:31) - Effects of consciousness on interacting with others (18:13) - Self vs consciousness, delusion vs belief, perception vs hallucination (29:59) - Evolutionary psychiatry (33:27) - The source of consciousness (40:20) - Theories of consciousness (50:08) - Interacting minds & future minds (59:01) - Religious/Spiritual views (1:01:27) - Altered states of consciousness (1:09:35) - Quantum consciousness & other minds (1:17:12) - Virtual realities, brains in vats, augmented bodies & sensory substitution (1:22:47) - Free will (1:26:44) - Chris' book recommendations (1:32:03) - Conclusion Website · YouTube
WATCH: https://youtu.be/80jTPjAOzeY Chris Frith is Emeritus Professor of Neuropsychology at the Wellcome Trust Centre for Neuroimaging at University College London (UCL), Visiting Professor at the Interacting Minds Centre at Aarhus University, Research Fellow at the Institute of Philosophy and Quondam Fellow of All Souls College, Oxford. A Fellow of the Academy of Medical Sciences from 1999, Chris was elected a Fellow of the British Academy in 2008 and an Honorary Fellow of the British Science Association in 2010. He has won numerous medals and awards for his significant contributions to neuroscience, including the 2009 European Latsis Prize alongside his wife, the developmental psychologist Uta Frith — also a Fellow of the Royal Society. CONNECT: - Website: https://tevinnaidu.com - Instagram: https://instagram.com/drtevinnaidu - Facebook: https://facebook.com/drtevinnaidu - Twitter: https://twitter.com/drtevinnaidu - LinkedIn: https://linkedin.com/in/drtevinnaidu TIMESTAMPS: (0:00) - Introduction (0:36) - Consciousness definition (level vs content) (3:57) - Function of consciousness (evolution) (6:52) - Consciousness & AI (11:31) - Effects of consciousness on interacting with others (18:13) - Self vs consciousness, delusion vs belief, perception vs hallucination (29:59) - Evolutionary psychiatry (33:27) - The source of consciousness (40:20) - Theories of consciousness (50:08) - Interacting minds & future minds (59:01) - Religious/Spiritual views (1:01:27) - Altered states of consciousness (1:09:35) - Quantum consciousness & other minds (1:17:12) - Virtual realities, brains in vats, augmented bodies & sensory substitution (1:22:47) - Free will (1:26:44) - Chris' book recommendations (1:32:03) - Conclusion Website · YouTube · YouTube
Karl Friston is a cognitive scientist and one of the pioneers of modern mathematical neuroscience. He is also a Fellow at the Wellcome Trust Centre for Neuroimaging at University College London. In this episode, Lexman interviews Karl Friston about his new book, "Stopping: The Science of Prevention." In this book, Karl Friston discusses the history of stopping, how it works, and the various ways it can be used to prevent crime and injury.
Grey Mirror: MIT Media Lab’s Digital Currency Initiative on Technology, Society, and Ethics
In this episode, theoretical neuroscientist and authority on brain imaging Karl Friston, helps us understand his Free Energy Principle (FEP) for how life works and evolves. We tackle this theory from five different perspectives to gain a deeper understanding; all the way from RNA and primordial soup to the future and safety of artificial intelligence. The Free Energy Principle describes with mathematical precision how the brain conserves energy by minimizing surprise. Life at every scale of organization, from single cells to the human brain, is driven by the same universal imperative. This idea has a very great influence and affects the way we work and organize ourselves socially. But how does this abstract principle translate into our everyday lives? The brain is continuously engaged in an act of interpretation called active inference that explains how we actively forage in the world for evidence that best satisfies our expectations. Active inference is a corollary of the FEP and is the process through which we build models of our environment that we update with evidence we actively collect. Those familiar with statistics will recognize this description of the brain as particularly Bayesian. SUPPORT US ON PATREON: https://www.patreon.com/rhyslindmark JOIN OUR DISCORD: https://discord.gg/PDAPkhNxrC Who is Karl Friston? Karl Friston is a theoretical neuroscientist and authority on brain imaging. He is a Professor at Institute of Neurology, University College London and, Wellcome Trust Principal Fellow and Scientific Director of the Wellcome Trust Centre for Neuroimaging Prof. Friston gained a reputation as the main proponent of the free energy principle, active inference and predictive coding theory, and is the inventor of statistical parametric mapping, voxel-based morphometry and dynamic causal modeling. “Karl Friston's free energy principle might be the most all-encompassing idea since Charles Darwin's theory of natural selection” Topics: Welcome Karl Friston to The Rhys Show: (00:00) What is FEP / active inference* & how does it apply in our daily life?: (01:39) Understanding Free Energy Principle from 5 different perspectives: (04:26) Information pre replicators / FEP pre sentient life: (00:00) Distinction between animate & inanimate kinds / Predictive capacity / Markov blanket: (12:40) Inanimate things that can exist based off of the law of physics: (18:23) FEP compared to the principles of natural selection & evolution: (24:11) RNA replicating in primordial soup; RNA a model of its environment?: (29:59) About the brain / mutual predictability: (37:19) Kind of information a bayesian brain can encode: (46:21) How free energy applies to social systems: (54:27) Cristianity a sense of a generative model: (01:02:57) How free energy applies with machines and AI / AI safety & generative models that include us: (01:06:17)
You can check out the Declassified MOD film on the Lyme Bay Trials here (a clip of this appears in the show audio) : https://www.youtube.com/watch?v=OTwQJ1ASyws&t=302s You can also check out various documentaries and excerpts of press coverage of the Zinc Cadmium and Lyme Bay Trials produced when these issues first hit the headlines over at https://www.youtube.com/user/experimentsrus/featured INDEPENDENT REVIEW OF THE POSSIBLE HEALTH HAZARDS OF THE LARGE-SCALE RELEASE OF BACTERIA DURING THE DORSET DEFENCE TRIALS Professor Brian G. Spratt FRS, Wellcome Trust Centre for the Epidemiology of Infectious Disease, University of Oxford. https://zeltus.eu/mre/downloads/dorset_bacteria_trials.pdf Zinc Cadmium Sulphide Dispersion Trials Report by the Academy of Medical Sciences to the Chief Scientific Adviser, Ministry of Defence on the Zinc Cadmium Sulphide dispersion trials undertaken in the United Kingdom between 1953 and 1964. December 1999 https://acmedsci.ac.uk/file-download/34958-ZincCadm.pdf For a recent historical appraisal of these issues, other open-air trials in the UK- as well as public and technical/ expert discourse on these matters see also: Ulf Schmidt ( 2015) Secret Science, Chapter 7.
In this episode, I talk with Cathy Price, Professor of Cognitive Neuroscience and Director of the Wellcome Trust Centre for Neuroimaging at University College London, about her pioneering work on functional neuroimaging of the language network, whether there are really such things as “language regions”, degeneracy, predicting and explaining language outcomes after stroke, and more.Price C, Wise R, Ramsay S, Friston K, Howard D, Patterson K, Frackowiak R. Regional response differences within the human auditory cortex when listening to words. Neurosci Lett 1992; 146: 179-82. [doi]Price CJ, Wise RJS, Warburton EA, Moore CJ, Howard D, Patterson K, Frackowiak R, Friston K. Hearing and saying. Brain 1996; 119: 919-31. [doi]Price CJ, Friston KJ. Degeneracy and cognitive anatomy. Trends Cogn Sci 2002; 6: 416-21. [doi]Crinion J, Price CJ. Right anterior superior temporal activation predicts auditory sentence comprehension following aphasic stroke. Brain 2005; 128: 2858-71. [doi]Price CJ, Seghier ML, Leff AP. Predicting language outcome and recovery after stroke: the PLORAS system. Nat Rev Neurol 2010; 6: 202-10. [doi]Price CJ. A review and synthesis of the first 20 years of PET and fMRI studies of heard speech, spoken language and reading. NeuroImage 2012; 62: 816-47. [doi]Hope TMH, Seghier ML, Leff AP, Price CJ. Predicting outcome and recovery after stroke with lesions extracted from MRI images. NeuroImage Clin 2013; 2: 424-33. [doi]Seghier ML, Price CJ. Interpreting and utilising intersubject variability in brain function. Trends Cogn Sci 2018; 22: 517-30. [doi]Price lab websiteTranscript
Sir John Bell, Regius Professor of Medicine at Oxford University, joins Bertrand Bodson on the latest episode of the Pharma Unlimited podcast. Sir John founded the Wellcome Trust Centre for Human Genetics, and most recently led the program for the AstraZeneca-Oxford COVID-19 vaccine. Sir John tells the story of the Oxford vaccine, and takes a closer look at how the pharma industry might handle risk differently in the future.
This week, we bring you two stories about the struggle to find balance during the COVID-19 pandemic, whether it's as a scientist, a mother, or all of the above. Part 1: Psychiatrist Xiaosi Gu studies COVID-19's impact on mental health, just as her own begins to deteriorate. Part 2: Stacey Bader Curry's family and career are thriving — until the pandemic throws it all into chaos. Dr. Xiaosi Gu is one of the foremost researchers in the area of computational psychiatry. Her research examines the neural and computational mechanisms underlying human beliefs, decision making, and social interaction in both health and disease, through a synthesis of neuroscience, cognitive science, and behavioral economics approaches. After receiving a Bachelor's degree in Psychology and Economics from Peking University in Beijing, Dr. Gu moved to New York City to pursue a Ph.D. in Neuroscience at the Icahn School of Medicine at Mount Sinai. Dr. Gu then completed her postdoctoral training in computational psychiatry at Virginia Tech and the Wellcome Trust Centre for Neuroimaging, University College London (UCL). During her time in London, she founded the world's first computational psychiatry course at UCL. Before re-joining Mount Sinai, Dr. Gu held faculty positions at the University of Texas, Dallas and UT Southwestern Medical Center. She is currently an Assistant Professor in Psychiatry and Neuroscience, and a Principal Investigator at the Friedman Brain Institute and the Addiction Institute at Mount Sinai. Stacey Bader Curry is a writer and storyteller who lives in Maine. She is an 8-time Moth Slam winner, including a Grand Slam, and has performed on PBS' Stories From the Stage, and many podcasts. Learn more about your ad choices. Visit podcastchoices.com/adchoices
“We're just at the cusp of the genetic therapeutics revolution, which I think will continue to sweep medicine for the next 15 to 20 years and will completely fundamentally change the way we think about treating all kinds of diseases.” In this week's episode of The G Word #sciencepodcast, our CEO Chris Wigley is joined by Prof Sir John Bell, Regius Professor of Medicine at Oxford University. Prof Bell has been extensively involved in the development of research programmes in genomics and genetics as well in the development of a clinical research programme in the UK. He is the founder of the Wellcome Trust Centre for Human Genetics and is the founding director of three biotechnology start-up companies. As well as receiving a number of awards and honours, he has a number of charity positions and was selected to the Vaccine Taskforce in 2020. Prof Bell also assisted in the development of the 100,000 Genome Project at Genomics England. Today John talks about the new operating model - Our Future Health. As the leader of the programme, he discusses how it has the potential to transform the way people are treated in cancer. He also discusses how new technologies have improved genomics and how they have transformed our thinking around cancer.
What are #psychedelics and can they help with #mental illness? What could #LSD and #psilocybin (magic mushrooms) do to help with #depression? Katrin Preller received her M.Sc. (Neuropsychology and Clinical Psychology) from University of Konstanz, Germany. She joined the University of Zurich where she investigated the neurobiological long-term effects of cocaine, MDMA, and heroin use. After completing her PhD, she investigated the effects of psychedelics on self-perception and social cognition. She worked at the Wellcome Trust Centre for Neuroimaging, UCL, London, and Yale University, New Haven. Subsequently, she was appointed as Junior Group Leader at the University of Zurich, and holds a position as Visiting Assistant Professor at Yale University. Follow her on Twitter @KatrinPreller! Brain Health with Dr. Nissen brings you advancements in medicine, #neuroscience, psychiatry, and #nutrition to help you live a better life. Dr. Nissen's expert interviews reveal new, evidence-based approaches to enhancing mental health, sharpening cognition, and optimizing performance. With topics such as #optogenetics, #Alzheimer's disease, #neuromodulation, #depression, the Mediterranean #Diet, and #psychedelics, this show is sure to expose listeners to new topics on the frontiers of medicine and neuroscience. Join our community at http://drnissen.com Support us on Patreon: https://www.patreon.com/drnissen Subscribe to the podcast at https://podcasts.apple.com/us/podcast/brain-health-with-dr-nissen/id1510757864 Dr. Nissen is a medical doctor (MD) and therapist. This show is intended for entertainment and educational purposes only and does not substitute personalized medical advice. Please speak with your doctor before attempting any medical or major diet and lifestyle changes. Check out Dr. Nissen's new children's book on empathy and emotional intelligence, Emily Empathy! http://bit.ly/emilyempathy
What is a virus? How can we spot human viruses in danger of becoming pandemics? How can we use statistics to understand their origins and transmission? This turns out to be a hard problem - not least because there can be many hundreds or thousands of slightly modified strains of a virus in a small sample of blood. It is of great importance which version of a virus will become a pandemic in a population and which will merely peter out.Viral geneticists have to be expert statisticians to be able to disentangle this story. Fundamentally if we can use statistical techniques to understand which versions of a virus are prevalent and where they originated from we can start to design counter measures to defeat the further spread of the virus.We speak to statistician and data scientist Dr. Kat James about her DPhil and post-doctoral work on the statistical genetics of animal-human viruses, in particular HIV-2, at the Nuffield Department of Medicine and the Wellcome Trust Centre for Human Genetics, University of Oxford. She is now Head of Data Science at Royal Mail and has some some valuable insights on the crossover between statistical genetics and data science.As we discover, the current coronavirus pandemic is a so-called zoonotic virus - which means it transitioned from animals to humans at some point and has become a very successful virus in the human population. COVID-19 has similarities to influenza, HIV-1 and HIV-2, MERS and SARS as we will discover in this episode and Kat gives us some interesting lessons to learn from previous pandemics.Background on HIVHIV-1 is one of the major viral pandemics of the 20th century. Untreated, it has a greater than 95% probability of death and it has killed 33 million people (it still accounts for 750,000 deaths per year).Using statistical genetics, researchers have been able to identify 3 spillover events into humans for HIV-1. Human viruses often interact with developments in human geography as part of the infection dynamics and this is certainly true of HIV-1 over the course of its emergence as a pandemic virus.HIV-2 is a distinct but similar virus to HIV-1 and people who are infected with HIV-2 often demonstrate resistance to HIV-1. Eight spillover events from Mangabey monkeys have been identified for HIV-2.With interview guest Dr. Kat James who is now Head of Data Science at Royal Mail.Further readingPaper: Low-Bias RNA Sequencing of the HIV-2 Genome from Blood Plasma (via Journal of Virology, American Society for Microbiology)Article: Introduction to PCR amplification (via Kahn Academy)Article: Tracking COVID19: Coronavirus came to UK 'on at least 1,300 separate occasions' (reporting on work by Universities of Birmingham and Oxford via BBC News website)Some links above may require payment or login. We are not endorsing them or receiving any payment for mentioning them. They are provided as is. Often free versions of papers are available and we would encourage you to investigate.Recording date: 7 July 2020Interview date: 9 June 2020
Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas
If you tell me that one of the world’s leading neuroscientists has developed a theory of how the brain works that also has implications for the origin and nature of life more broadly, and uses concepts of entropy and information in a central way — well, you know I’m going to be all over that. So it’s my great pleasure to present this conversation with Karl Friston, who has done exactly that. One of the most highly-cited neuroscientists now living, Friston has proposed that we understand the brain in terms of a free energy principle, according to which our brains are attempting to model the world in such a way as to minimize the amount of surprise we experience. It’s a bit more complicate than that, but I think we made great headway in explicating some very profound ideas in a way that should be generally understandable.Support Mindscape on Patreon.Karl Friston received his medical degree from King’s College Hospital, London. He is currently Professor at the Institute of Neurology, University College London, and Wellcome Principal Research Fellow and Scientific Director of the Wellcome Trust Centre for Neuroimaging. Among his major contributions are statistical parametric mapping, voxel-based morphometry, and dynamical causal modeling. He is a Fellow of the Royal Society, of the Academy of Medical Science, and of the Royal Society of Biology. Among his awards are the Young Investigators Award in Human Brain Mapping, the Minerva Golden Brain Award, the Weldon Memorial Prize, the Charles Branch Award, and the Glass Brain Award for human brain mapping.Web pageGoogle Scholar publicationsTalk on “I Am, Therefore I Think”Article on “The Free-Energy Principle: A Unified Brain Theory?”Wikipedia
Juan Fernández Tajes estuda a xenética humana de doenzas como a diabetes no Wellcome Trust Centre da Universidade de Oxford. Pero nos seu inicios no mundo da investigación empezou estudando as navallas galegas, que estaban mal catalogadas. Con esta entrevista, o noso correspondente temporal en Londres Juan Picos despide a súa sección. Para que un novo fármaco chegue aos pacientes ten que ser efectivo e seguro, pero tamén compre que estea protexido e viable a súa produción. Todo isto o tiveron en conta no departamento de tecnoloxía farmacéutica da USC para produción dun fármaco contra a metástase do cancro de colon. O equipo de Alejandro Sánchez Barreiro gañou o premio 2018 de investigación da Real Academia de Ciencias por este traballo. O proxecto INVERBIS é un dos 7 que veñen de ser seleccionados na segunda edición do programa Ignicia Proba de Concepto da Axencia Galega de Innovación, GAIN, da Xunta de Galicia. Escoitamos a Senén Barro, catedrático de Ciencia da Computación e intelixencia artificial da USC e dirixe o grupo de sistemas intelixentes do CITIUS, e a Pedro Arenas e Verónica Castelo de GAIN. Un pigmento azul mais valioso que o ouro é a peza clave no misterio do monxa do dente azul. Nolo conta a nosa Deborah Garcia Bello.
Juan Fernández Tajes estuda a xenética humana de doenzas como a diabetes no Wellcome Trust Centre da Universidade de Oxford. Pero nos seu inicios no mundo da investigación empezou estudando as navallas galegas, que estaban mal catalogadas. Con esta entrevista, o noso correspondente temporal en Londres Juan Picos despide a súa sección. Para que un novo fármaco chegue aos pacientes ten que ser efectivo e seguro, pero tamén compre que estea protexido e viable a súa produción. Todo isto o tiveron en conta no departamento de tecnoloxía farmacéutica da USC para produción dun fármaco contra a metástase do cancro de colon. O equipo de Alejandro Sánchez Barreiro gañou o premio 2018 de investigación da Real Academia de Ciencias por este traballo. O proxecto INVERBIS é un dos 7 que veñen de ser seleccionados na segunda edición do programa Ignicia Proba de Concepto da Axencia Galega de Innovación, GAIN, da Xunta de Galicia. Escoitamos a Senén Barro, catedrático de Ciencia da Computación e intelixencia artificial da USC e dirixe o grupo de sistemas intelixentes do CITIUS, e a Pedro Arenas e Verónica Castelo de GAIN. Un pigmento azul mais valioso que o ouro é a peza clave no misterio do monxa do dente azul. Nolo conta a nosa Deborah Garcia Bello.
Spotkanie z prof. Vivianem Nuttonem odbyło się 13 grudnia w Instytucie Historii UŁ. Prelekcja była częścią cyklu wykładów otwartych poświęconych historii medycyny, organizowanych pod patronatem JM Rektora Uniwersytetu Łódzkiego oraz La Société Française d'Histoire de la Médecine. Celem spotkań jest zapoznanie publiczności z dziedzictwem antycznej myśli medycznej i jej nowożytnym odbiorem. Organizatorami przedsięwzięcia są: Centrum Ceraneum, Wydział Filozoficzno-Historyczny i Wydział Filologiczny Uniwersytetu Łódzkiego. Profesor Nutton specjalizuje się w historii medycyny od czasu antyku do nowożytności, w lecznictwie grecko-rzymskim i jego recepcji w okresie odrodzenia. W czasie wykładu przedstawił efekty przeprowadzonych w ostatnich latach analiz nieznanych wcześniej pism Galena. Rzuciły one nowe światło na poglądy starożytnego lekarza nt. anatomii, psychologii i filozofii, jak również instytucji kulturalnych Imperium Rzymskiego. Vivian Nutton pracował na swym macierzystym Uniwersytecie w Cambridge i w Wellcome Trust Centre for the History of Medicine, związany był również z Centre for the History of Medicine na University College London. Jest autorem artykułów naukowych zebranych m.in. w serii Variorum w tomie „From Democedes to Harvey: Studies in the History of Medicine” oraz przekrojowej monografii „Ancient Medicine” i haseł nt. medycyny w encyklopedii „Der neue Pauly”. Najnowszą pracą Profesora jest „Principles of anatomy according to the opinion of Galen, by Johann Guinter and Andreas Vesalius (2017)”. Obecnie pełni funkcję współredaktora serii Medical History. Jest członkiem międzynarodowych towarzystw naukowych, w tym Akademii Brytyjskiej, Academia Europaea i Académie des inscriptions et belles-lettres.
This episode tells the story of a team of scientists and doctors from Newcastle’s Wellcome Trust Centre for Mitochondrial Research who spent years campaigning strenuously, alongside patients, to persuade UK policymakers to pass a law that would permit the use of a pioneering but controversial fertility treatment The team from Newcastle hoped that the IVF treatment, known as mitochondrial donation, might halt the transmission from one generation to the next of a devastating, incurable and often fatal condition - mitochondrial disease - that blights the lives of many thousands of families across the world. In 2015 the five year long campaign reached a dramatic conclusion when Parliament made its landmark vote on whether or not the treatment should be allowed in the UK. It was huge victory for the campaigners, shared amongst the doctors, scientists, patients and their families but much credit has to go to the man who spearheaded the campaign, Professor Sir Doug Turnbull. Professor Turnbull is one of the world’s leading experts of mitochondrial disease and last year he was given a knighthood in recognition of his dedication, spanning decades, to the study of the disease and to the care of patients afflicted by it. I’ve been fortunate enough to work with Doug and his team for a few years on their public engagement projects but my involvement with their work started after the climax of this dramatic story of their Parliamentary success, so I was very excited to sit down with Doug a few weeks ago to hear all about the campaign from his perspective, as well as hearing his insights generally into the power of public engagement. To learn more about the work of Doug and his team check out their website. You can also watch the videos I produced for them explaining what mitochondrial disease is and telling the stories of people whose lives have been impacted by the disease: Beth's Story Kim and Betsy's Story Stuart's Story For more information, insights, resources and inspiration for communicating research in a digital age please check out my Research Comms Blog
Georgina Ferry interviews Elizabeth Robertson. Elizabeth Robertson FRS is Professor of Developmental Biology and a Wellcome Trust Principal Fellow at the Dunn School. Having spent her early childhood collecting animals as pets in Nigeria, she came to Oxford in 1975 to read for a degree in zoology. She then went to Cambridge to do a PhD on cell differentiation during development. She was one of the first to isolate embryonic stem cells in the mouse, and began her career as an independent scientist in 1988 at Columbia University in New York, manipulating embryonic cells and generating lines of mice that bore the corresponding phenotypes - a technique called gene targeting. She subsequently moved to Harvard, using this technique to study the patterning of the mouse body plan and identifying key transcription factors. She returned to Oxford in 2004 as part of the newly-formed Wellcome Trust Centre for Human Genetics, and five years later accepted Herman Waldmann's invitation to move her lab to the expanding Dunn School. Her work on the early embryos of mice continues to elucidate mutations in the genes for regulatory proteins that give rise to developmental abnormalities in humans.
Brian Mackenwells tries to smuggle something onto the vomit comet, and Jess Thom learns the best way to explain her Tourette's to someone new. Brian Mackenwells currently works at the Wellcome Trust Centre for Human Genetics as the Public Engagement Officer. For the seven years before that he worked at "Science Oxford", an Oxford-based science communication charity, developing and delivering science shows and workshops to all ages of young people. In his spare time he acts and directs as part of an amateur dramatics group, and co-writes the monthly audio-drama podcast "Action Science Theatre". He has also derived E=MC^2 live on stage in the back room of a pub, floated in zero gravity, and has only made two children cry in the course of his public engagement career to date. Jess Thom is co-founder of Touretteshero and may or may not lead a secret double life as a superhero. Artist, playworker, and expert fundraiser, Jess currently helps coordinate a large play project in South London. Jess has had tics since she was a child but wasn’t diagnosed with Tourettes until she was in her twenties. With some encouragement from her friends, Jess decided to turn her tics into a source of imaginative creativity and the Touretteshero project was born. Learn more about your ad choices. Visit megaphone.fm/adchoices
En 2009 entraba en contacto, por primera vez, con el Wellcome Trust de forma directa. Vamos, que venía por primera vez a Londres, de estancia predoctoral, en el Wellcome Trust Centre for the History of Medicine at UCL. Un año después, y por motivo que no quedaron claros, se cerró el centro. El Wellcome Trust decidió no renovar su financiación (8.8 millones de libras entre 2005 y 2010), y eso inició el proceso de disolución, culminado en 2 años. Hoy os cuento por qué creo que pasó. Como siempre, más contenido en la web: jmzaragoza.net
Hoy hablamos de Roger Cooter, historiador de la medicina que trabajó en el Wellcome Trust Centre for the History of Medicine at UCL, hasta el cierre del mismo en 2010. Cooter escribió, en la década de los 2000, dos artículos que tuvieron un gran recorrido, y que cuestionaban la vigencia de la historia social de la medicina tras la crítica postmoderna. Ayer me compré el que es su último libro: una suerte de memoria profesional en el que nos habla de este y otros momentos de su vida. Con esta excusa, hablamos de él.
An evening of storytelling and music where researchers from the Wellcome Trust Centre for Human Genetics, the Jenner Institute, and Cancer Research UK came together to tell stories about their lives as scientists, with live musical accompaniment. On the 10th of October 2015, The Wellcome Trust Centre for Human Genetics, with support from Cancer Research UK and The Wellcome Trust, put on an evening of storytelling and music where researchers from the Centre, the Jenner Institute, and Cancer Research UK came together to tell stories about their lives as scientists, with live musical accompaniment from Oxford-based folk band “James Bell and the Half Moon All Stars”. It took place under the dinosaurs at the Oxford University Museum of Natural History, and our speakers were Irina Pulyakhina (WTCHG), Anna Fowler (WTCHG), Erwan Atcheson (Jenner), Portia Westall (WTCHG), and Daniel Bulte (CRUK). This track contains the entire evening, but you can listen to specific sections of it in the other tracks in this series.
Anna Fowler, from the Lunter group at the WTCHG, speaks about how the patterns around a close-call in the desert makes her think about her work. This is the second part of our evening of storytelling and music, where researchers from the Wellcome Trust Centre for Human Genetics, the Jenner Institute, and Cancer Research UK, came together to tell stories about their lives as scientists, with live musical accompaniment from Oxford-based folk group “James Bell and the Half Moon All Stars”. It took place under the dinosaurs at the Oxford University Museum of Natural History.
Erwan Atcheson, from the Jenner Institute, speaks about his time studying parasitic worms, and the worries that come with it. This is the third part of our evening of storytelling and music, where researchers from the Wellcome Trust Centre for Human Genetics, the Jenner Institute, and Cancer Research UK, came together to tell stories about their lives as scientists, with live musical accompaniment from Oxford-based folk group “James Bell and the Half Moon All Stars”. It took place under the dinosaurs at the Oxford University Museum of Natural History.
Portia Westall, from the Donnelly group at the WTCHG, speaks about how she thinks about music when working on DNA sequences. This is the fourth part of our evening of storytelling and music, where researchers from the Wellcome Trust Centre for Human Genetics, the Jenner Institute, and Cancer Research UK, came together to tell stories about their lives as scientists, with live musical accompaniment from Oxford-based folk group “James Bell and the Half Moon All Stars”. It took place under the dinosaurs at the Oxford University Museum of Natural History.
Daniel Bulte, from the Department of Oncology, speaks about what happens when they discover an ‘incidental finding’. This is the final part of our evening of storytelling and music, where researchers from the Wellcome Trust Centre for Human Genetics, the Jenner Institute, and Cancer Research UK, came together to tell stories about their lives as scientists, with live musical accompaniment from Oxford-based folk group “James Bell and the Half Moon All Stars”. It took place under the dinosaurs at the Oxford University Museum of Natural History.
Irina Pulyakhina, from the Julian Knight group at the WTCHG, speaks about her time helping a Masters student through an important presentation. This is the first part of our evening of storytelling and music, where researchers from the Wellcome Trust Centre for Human Genetics, the Jenner Institute, and Cancer Research UK, came together to tell stories about their lives as scientists, with live musical accompaniment from Oxford-based folk group “James Bell and the Half Moon All Stars”. It took place under the dinosaurs at the Oxford University Museum of Natural History.
Sarah Keer-Keer, Public Engagement, Outreach & Communications Manager at the Wellcome Trust Centre for Cell Biology, presents this year’s Tam Dalyell Prize lecture entitled, "Life Through a Lens". This lecture reveals how taking a dramatic, artistic and fun approach to science helps cell biologists communicate with the public and how in turn the public have inspired the scientists. Join Sarah who will guide you through hundreds of years of science, up to the present day, when we will discover who today's scientists really are. This lecture was part of the 2015 Edinburgh International Science Festival. Recorded on 4 April 2015 at the University of Edinburgh's Playfair Library.
Dr Jenny Taylor is the Programme Director for the Genomic Medicine Theme, Wellcome Trust Centre for Human Genetics. Her research bridges the gap between genetics research and the use of its discoveries in diagnosis or treatment of medical conditions. Clinical diagnoses can be broad descriptions, but today's test results can help better understand the condition as well as target treatment. Cancer is a good example in which personalised medicine can help decide which molecular targeted therapy is most appropriate.
Dr Jenny Taylor is the Programme Director for the Genomic Medicine Theme, Wellcome Trust Centre for Human Genetics. Her research bridges the gap between genetics research and the use of its discoveries in diagnosis or treatment of medical conditions. Clinical diagnoses can be broad descriptions, but today's test results can help better understand the condition as well as target treatment. Cancer is a good example in which personalised medicine can help decide which molecular targeted therapy is most appropriate.
Dr Jenny Taylor is the Programme Director for the Genomic Medicine Theme, Wellcome Trust Centre for Human Genetics. Her research bridges the gap between genetics research and the use of its discoveries in diagnosis or treatment of medical conditions. Clinical diagnoses can be broad descriptions, but today's test results can help better understand the condition as well as target treatment. Cancer is a good example in which personalised medicine can help decide which molecular targeted therapy is most appropriate.
Dr Jenny Taylor is the Programme Director for the Genomic Medicine Theme, Wellcome Trust Centre for Human Genetics. Her research bridges the gap between genetics research and the use of its discoveries in diagnosis or treatment of medical conditions. Clinical diagnoses can be broad descriptions, but today's test results can help better understand the condition as well as target treatment. Cancer is a good example in which personalised medicine can help decide which molecular targeted therapy is most appropriate.
Dame Bridget Ogilvie discusses her life and illustrious scientific career, at The Wellcome Trust Centre for Human Genetics’ Women in Science series From studying rural science in Australia to researching immune responses to parasites in Cambridge, Dame Bridget Ogilvie has dedicated her own career to building and supporting the research careers of others.
Interview with Professor Peter Donnelly The Nuffield Department of Medicine recognises the challenge of balancing work-life commitments and encourages staff to make use of the range of University services and facilities to support them with this. Dr Jenny Taylor interviews Professor Peter Donnelly about how the Wellcome Trust Centre for Human Genetics encourages its employees to have a better work-life balance. They discuss the initiatives taken by the Centre including: inclusive scheduling of events, mentoring schemes and financial support for women returning from maternity leave. Professor Donnelly draws on his own experience, in the Statistical Genetics field, about the challenges faced by women at different stages of their careers. He believes that it is important to talk honestly about the challenges faced by people juggling careers and family, and to highlight examples where it works well.
A hepatologist and academic, a wife and a mother of two, Dr Ellie Barnes delighted researchers at the Wellcome Trust Centre for Human Genetics’ Women in Science talk, held on Wednesday the 20th of November 2013 Her presentation entitled: Women in Science – the joys and the juggles, highlighted the ups and downs of balancing a career in science, particularly as a working mother. Currently balancing three major projects: leading a £5 million collaboration called Stop HCV, trialling a powerful new Hepatitis C vaccine, and studying B cell immunology and IgG4 systemic disease, Ellie is now at a senior level in her career. But she admited that getting to this point hasn’t exactly been smooth sailing. Having her first child while studying her PhD and second just before receiving her intermediate MRC award, Ellie said it’s often hard to manage the demands of work and home, but being able to do what you love day in and day out makes it worth the struggle.
Interview with Professor Peter Donnelly The Nuffield Department of Medicine recognises the challenge of balancing work-life commitments and encourages staff to make use of the range of University services and facilities to support them with this. Dr Jenny Taylor interviews Professor Peter Donnelly about how the Wellcome Trust Centre for Human Genetics encourages its employees to have a better work-life balance. They discuss the initiatives taken by the Centre including: inclusive scheduling of events, mentoring schemes and financial support for women returning from maternity leave. Professor Donnelly draws on his own experience, in the Statistical Genetics field, about the challenges faced by women at different stages of their careers. He believes that it is important to talk honestly about the challenges faced by people juggling careers and family, and to highlight examples where it works well.
Dame Bridget Ogilvie discusses her life and illustrious scientific career, at The Wellcome Trust Centre for Human Genetics’ Women in Science series From studying rural science in Australia to researching immune responses to parasites in Cambridge, Dame Bridget Ogilvie has dedicated her own career to building and supporting the research careers of others.
A hepatologist and academic, a wife and a mother of two, Dr Ellie Barnes delighted researchers at the Wellcome Trust Centre for Human Genetics’ Women in Science talk, held on Wednesday the 20th of November 2013 Her presentation entitled: Women in Science – the joys and the juggles, highlighted the ups and downs of balancing a career in science, particularly as a working mother. Currently balancing three major projects: leading a £5 million collaboration called Stop HCV, trialling a powerful new Hepatitis C vaccine, and studying B cell immunology and IgG4 systemic disease, Ellie is now at a senior level in her career. But she admited that getting to this point hasn’t exactly been smooth sailing. Having her first child while studying her PhD and second just before receiving her intermediate MRC award, Ellie said it’s often hard to manage the demands of work and home, but being able to do what you love day in and day out makes it worth the struggle.
Dr Ellie Williams interviews Associate Professor Erika Mancini, a Group Head in the Wellcome Trust Centre for Human Genetics, about her experiences as a woman in science. Erika started out her career as a physicist before moving to microbiology. They discuss Erika's career pathway, Dorothy Hodgkin and whether Erika thinks things are changing for women in science.
A hepatologist and academic, a wife and a mother of two, Dr Ellie Barnes delighted researchers at the Wellcome Trust Centre for Human Genetics’ Women in Science talk, held on Wednesday the 20th of November 2013. Her presentation entitled: Women in Science – the joys and the juggles, highlighted the ups and downs of balancing a career in science, particularly as a working mother. Currently balancing three major projects: leading a £5 million collaboration called Stop HCV, trialling a powerful new Hepatitis C vaccine, and studying B cell immunology and IgG4 systemic disease, Ellie is now at a senior level in her career. But she admited that getting to this point hasn’t exactly been smooth sailing. Having her first child while studying her PhD and second just before receiving her intermediate MRC award, Ellie said it’s often hard to manage the demands of work and home, but being able to do what you love day in and day out makes it worth the struggle.
Short film introducing the Wellcome Trust for Human Genetics In the first decades of the 21st century, researchers are beginning to understand in detail how our genetic inheritance makes us who we are. At the Wellcome Trust Centre for Human Genetics, our aim is to extend that understanding in order to gain a clearer insight into mechanisms of health and disease. Looking across all three billion letters of the human genetic code, we aim to pinpoint variant spellings and discover how they increase or decrease an individual’s risk of falling ill. The WTCHG is a research institute of the Nuffield Department of Medicine at the University of Oxford, funded by the University, the Wellcome Trust and numerous other sponsors. It is based in purpose-built laboratories on the University of Oxford’s Biomedical Research Campus in Headington, one of the largest concentrations of biomedical expertise in the world. With more than 400 active researchers and around 70 employed in administrative and support roles, the Centre is an international leader in genetics, genomics and structural biology. We collaborate with research teams across the world on a number of large-scale studies in these areas. Our researchers expend close to £20m annually in competitively-won grants, and publish around 300 primary papers per year.
Professor Yvonne Jones tells us how structural biology was brought into the field of immunology in Oxford, at the Wellcome Trust Centre for Human Genetics. Professor Jones also explains the developments of her current research on cell surface receptors as mediators of nerve cells guidance.
"Carl Gustav Jung and the Red Book," an all day symposium, featured presentations by prominent Jungian scholars. Speaker Biography: Jung scholar Sonu Shamdasani is a London-based author, editor, and professor at the Wellcome Trust Centre for the History of Medicine at University College London WIHM/UCL. Shamdasani works discuss the history of psychiatry and psychology from the mid-nineteenth century to current times. Shamdasani holds a BA from Bristol University, followed by MSc, History of Science and Medicine, University College London/Imperial College and gained his Ph.D. in History of Medicine from WIHM/UCL. Speaker Biography: James Hillman is a psychologist, scholar, international lecturer, pioneer psychologist, and the author of more than twenty books. Hillman has held teaching positions at Yale University, the University of Chicago, Syracuse University, the University of Chicago, and the University of Dallas, where he cofounded the Dallas Institute of Humanities and Culture. Speaker Biography: Ann Ulanov is a professor of psychiatry and religion at the Union Theological Seminary in New York City. She is the author of several books, including Religion and the Spiritual in Carl Jung and The Healing Imagination: The Meeting of Psyche and Soul. For captions, transcript, and more information visit http://www.loc.gov/today/cyberlc/feature_wdesc.php?rec=4909
Meet our Division of Structural Biology. The Division of Structural Biology (STRUBI) is part of the Nuffield Department of Clinical Medicine (NDM) at the University of Oxford. STRUBI is also part of the Wellcome Trust Centre for Human Genetics. The Division includes the Oxford Protein Production Facility (OPPF) and the Oxford Particle Imaging Centre (OPIC).
Calling all pessimists! Your brain is wired for optimism! Yes, deep down, we're all Pollyannas. So wipe that scowl off your face and discover the evolutionary advantage of thinking positive. Also, enjoy other smile-inducing research suggesting that if you crave happiness, you should do the opposite of what your brain tells you to do. Plus, why a “well-being index” may replace Dow Jones as a metric for success … a Twitter study that predicts your next good mood … and whether our furry and finned animal friends can experience joy. Guests: • Frank Drake – Trustee at the SETI Institute and author of the Drake Equation • Tali Sharot – Cognitive neuroscientist at the Wellcome Trust Centre for Neuroimaging at the University College London and the author of The Optimism Bias: A Tour of the Irrationally Positive Brain • Michael Macy – Sociologist at Cornell University His team's Twitter study: http://timeu.se/ • Carol Graham – Economist at the Brookings Institution and author of The Pursuit of Happiness: An Economy of Well-Being • David DiSalvo – Science and technology writer, author of What Makes Your Brain Happy and Why You Should Do the Opposite • Robin Ince – U.K.-based comedian • Jonathan Balcome – Animal behavior scientist and author of The Exultant Ark: A Pictorial Tour of Animal Pleasure Learn more about your ad choices. Visit megaphone.fm/adchoices
Calling all pessimists! Your brain is wired for optimism! Yes, deep down, we’re all Pollyannas. So wipe that scowl off your face and discover the evolutionary advantage of thinking positive. Also, enjoy other smile-inducing research suggesting that if you crave happiness, you should do the opposite of what your brain tells you to do. Plus, why a “well-being index” may replace Dow Jones as a metric for success … a Twitter study that predicts your next good mood … and whether our furry and finned animal friends can experience joy. Guests: • Frank Drake – Trustee at the SETI Institute and author of the Drake Equation • Tali Sharot – Cognitive neuroscientist at the Wellcome Trust Centre for Neuroimaging at the University College London and the author of The Optimism Bias: A Tour of the Irrationally Positive Brain • Michael Macy – Sociologist at Cornell University His team’s Twitter study: http://timeu.se/ • Carol Graham – Economist at the Brookings Institution and author of The Pursuit of Happiness: An Economy of Well-Being • David DiSalvo – Science and technology writer, author of What Makes Your Brain Happy and Why You Should Do the Opposite • Robin Ince – U.K.-based comedian • Jonathan Balcome – Animal behavior scientist and author of The Exultant Ark: A Pictorial Tour of Animal Pleasure
Chris Butler, academic clinical lecturer in neurology, University of Oxford, talks to Rebecca Cleary, research assistant, Wellcome Trust Centre for Neuro-imaging, UCL, about her research investigating whether the neural substrate in those with depression or anxiety is the same as in those with one of these disorders and also temporal lobe epilepsy.This podcast was recorded at the British NeuroPsychiatry Association’s 2013 AGM. For more information on the association and next year’s meeting, see bnpa.org.uk.
Professor Gil McVean tells us how statistical genetics helps us understand and treat disease. Prof Gil McVean is the Head of Bioinformatics and Statistical Genetics at the Wellcome Trust Centre for Human Genetics. His research covers several areas in the analysis of genetic variation, combining the development of methods for analysing high throughput sequencing data, theoretical work and empirical analysis.
Professor Gil McVean tells us how statistical genetics helps us understand and treat disease. Prof Gil McVean is the Head of Bioinformatics and Statistical Genetics at the Wellcome Trust Centre for Human Genetics. His research covers several areas in the analysis of genetic variation, combining the development of methods for analysing high throughput sequencing data, theoretical work and empirical analysis.
Professor Gil McVean tells us how statistical genetics helps us understand and treat disease. Genomic technology and statistical analysis of the genome is a powerful tool in understanding disease. Prof Gil McVean is the Head of Bioinformatics and Statistical Genetics at the Wellcome Trust Centre for Human Genetics. Professor McVean's research covers several areas in the analysis of genetic variation. Combining the development of methods for analysing high throughput sequencing data, theoretical work, and empirical analysis, this research may lead to genetic diagnosis and targeted treatments for disease.
Professor Gil McVean tells us how statistical genetics helps us understand and treat disease. Genomic technology and statistical analysis of the genome is a powerful tool in understanding disease. Prof Gil McVean is the Head of Bioinformatics and Statistical Genetics at the Wellcome Trust Centre for Human Genetics. Professor McVean's research covers several areas in the analysis of genetic variation. Combining the development of methods for analysing high throughput sequencing data, theoretical work, and empirical analysis, this research may lead to genetic diagnosis and targeted treatments for disease.
Calling all pessimists! Your brain is wired for optimism! Yes, deep down, we're all Pollyannas. So wipe that scowl off your face and discover the evolutionary advantage of thinking positive. Also, enjoy other smile-inducing research suggesting that if you crave happiness, you should do the opposite of what your brain tells you to do. Plus, why a “well-being index” may replace Dow Jones as a metric for success … a Twitter study that predicts your next good mood … and whether our furry and finned animal friends can experience joy. Guests: Frank Drake - Astronomer and author of the Drake Equation Tali Sharot - Cognitive neuroscientist at the Wellcome Trust Centre for Neuroimaging at the University College London and the author of The Optimism Bias: A Tour of the Irrationally Positive Brain Michael Macy - Sociologist at Cornell University His team's Twitter study: http://timeu.se/ Carol Graham - Economist at the Brookings Institution and author of The Pursuit of Happiness: An Economy of Well-Being David DiSalvo - Science and technology writer, author of What Makes Your Brain Happy and Why You Should Do the Opposite Robin Ince - U.K.-based comedian Jonathan Balcombe - Animal behavior scientist and author of The Exultant Ark: A Pictorial Tour of Animal Pleasure Descripción en español Learn more about your ad choices. Visit megaphone.fm/adchoices
Calling all pessimists! Your brain is wired for optimism! Yes, deep down, we’re all Pollyannas. So wipe that scowl off your face and discover the evolutionary advantage of thinking positive. Also, enjoy other smile-inducing research suggesting that if you crave happiness, you should do the opposite of what your brain tells you to do. Plus, why a “well-being index” may replace Dow Jones as a metric for success … a Twitter study that predicts your next good mood … and whether our furry and finned animal friends can experience joy. Guests: Frank Drake - Astronomer and author of the Drake Equation Tali Sharot - Cognitive neuroscientist at the Wellcome Trust Centre for Neuroimaging at the University College London and the author of The Optimism Bias: A Tour of the Irrationally Positive Brain Michael Macy - Sociologist at Cornell University His team’s Twitter study: http://timeu.se/ Carol Graham - Economist at the Brookings Institution and author of The Pursuit of Happiness: An Economy of Well-Being David DiSalvo - Science and technology writer, author of What Makes Your Brain Happy and Why You Should Do the Opposite Robin Ince - U.K.-based comedian Jonathan Balcombe - Animal behavior scientist and author of The Exultant Ark: A Pictorial Tour of Animal Pleasure Descripción en español
Introduction: Previous functional imaging studies comparing Chinese and English reading have reported that a left middle frontal region is more activated by Chinese reading and the left superior temporal cortex is more activated by English reading (Tan et al. 2001; 2003). We investigated this finding and its interpretation by conducting a functional magnetic resonance imaging (fMRI) study of reading in China and England using monolingual adolescents who spoke Mandarin or English respectively. Our paradigm compared activation for semantic decision on written stimuli (words or characters) as well as on pictures of objects so that we could determine whether or not the previously reported effects were specific to written stimuli. Methods: The paradigm involved 4 different stimulus conditions: semantic decisions on (1) written object names and (2) pictures of objects; and perceptual decisions on (3) pictures of meaningless non-objects and (4) meaningless Greek/Korean letters. Written stimuli were presented in the known language (i.e. characters in Chinese and words in English). The pictures were identical in the Chinese and English versions of the study. In each condition, three stimuli were presented, one above (the target) and two below (the choices). Using the right hand, participants were instructed to indicate with a left or right button press whether the target matched the left or right choice. For example, when the stimuli were “anchor” (target), “ship” and “truck”(choices), participants made a left button press to indicate that “anchor” is more closely associated with a “ship” than “truck”. Stimulus presentation parameters were identical for perceptual decisions but here the task was to indicate whether the left or right choice was perceptually identical to the target above. Data were acquired from the whole brain using 1.5T MRI scanners at Wellcome Trust Centre for Neuroimaging, UCL and Institute of Linguistics at XuZhou Normal University. Participants were 13 English adolescents (age 13-16) and 10 Chinese adolescents (age 13-16) with no history of reading impairment. Data analysis was carried out with SPM5 software package and effects of interest were based on correct responses only. Results and Conclusions Behaviourally, performance and response times did not differ across groups. In reading, consistent with previous findings, Chinese subjects showed significantly more activation in the left middle frontal region while English subjects showed significantly more activation in the left posterior superior temporal cortex. However, we also observed significantly greater left middle frontal activation in the Chinese group during semantic decisions on pictures. Therefore, the effect in the left middle frontal region is not specific to reading. Next, we explored inter-subject variability within each group. This led to the observation that differences between the Chinese and English groups were driven by a subgroup of English subjects. This suggests that the differences observed here at the group level were more likely to be due to individual differences in education or other cognitive skills than to writing system or ethnicity alone.
This presentation will present a range of collaborative research into the history and culture of Chinese medicine that has been undertaken in the last five years at the Wellcome Trust Centre for History of Medicine, UCL. Most of my personal research involves the translation, analysis and access to medical manuscripts that date from the 2nd to 11th C. CE. To this end I work with archaeologists, palaeographers, philologists, and medical historians all over China. Apart from books and article some of the fruits of one Wellcome Trust sponsored collaboration with the Academy of Chinese medicine can be seen online at the International Dunhuang Project site at the British Library. That project spawned a number joint ventures concerned with the transmission of medical knowledge and practice, particularly along the Silk Roads. More recently the first draft of a collection of Chinese medical illustrations is online in the Wellcome Images collection. These ca 1300 images dating from 2nd C. BCE to 20th C. come complete with catalogue details and descriptions of content. While these projects are mostly concerned with historical text and illustration they have contemporary relevance. Practitioners of traditional medicines in the modern have a different relationship to their history when compared with doctors of so-called modern medicine. They often, for example, call on the antiquity of their heritage as one form of legitimacy. Yet despite the overwhelming quantity of primary sources that history is poorly understood. As Secretary General of the International Association for the Study of Traditional Asian Medicine I established an academic journal dedicated to giving academics and practitioners a platform for the expression of their views, privileging the free exchange of knowledge over involvement in any particular commercial interest or therapeutic regime. Now in its third year we publish many articles by Chinese authors. Given the interdisciplinary nature of my research I work with a lively set of Phd and researchers whose research necessitates having a good understanding of many scripts and languages including Chinese, Tibetan, Arabic, Sanskrit etc and who are philologists, historians and anthropologists and film makers. Our output includes books, articles, and film. We have also recently run an outreach and arts project that engaged Asians living in London in the exploration of the everyday practice of Asian medicine in the home.
Melvyn Bragg and guests discuss the search for immunisation. In 1717, Lady Mary Wortley Montagu, the wife of the British Ambassador to the Ottoman Empire, wrote a letter to her friend describing how she had witnessed the practice of smallpox inoculation in Constantinople. This involved the transfer of material from a smallpox postule into multiple cuts made in a vein. Lady Montagu had lost her brother to smallpox and was amazed that the Middle Eastern practice of inoculation rendered the fatal disease harmless. In Britain, the practice was unknown. Inoculation was an early attempt at creating immunity to disease, but was later dismissed when Edward Jenner pioneered immunisation through vaccination in 1796. Vaccination was hailed a huge success. Napoleon described it as the greatest gift to mankind, but when the British government introduced the compulsory Vaccination Act in 1853, targeted at the poor and the working class, it sparked a mass opposition movement.How did a Gloucestershire country surgeon become known as the father of vaccination? Why did the British government introduce compulsory smallpox vaccination in 1853? What were the consequences of those who opposed it? And how was the disease finally eradicated? With Nadja Durbach, Associate Professor of History at the University of Utah, Chris Dye, Co-ordinator of the World Health Organisation's work on tuberculosis epidemiology, Sanjoy Bhattacharya, Lecturer in the Wellcome Trust Centre for the History of Medicine at UCL
Melvyn Bragg and guests discuss the search for immunisation. In 1717, Lady Mary Wortley Montagu, the wife of the British Ambassador to the Ottoman Empire, wrote a letter to her friend describing how she had witnessed the practice of smallpox inoculation in Constantinople. This involved the transfer of material from a smallpox postule into multiple cuts made in a vein. Lady Montagu had lost her brother to smallpox and was amazed that the Middle Eastern practice of inoculation rendered the fatal disease harmless. In Britain, the practice was unknown. Inoculation was an early attempt at creating immunity to disease, but was later dismissed when Edward Jenner pioneered immunisation through vaccination in 1796. Vaccination was hailed a huge success. Napoleon described it as the greatest gift to mankind, but when the British government introduced the compulsory Vaccination Act in 1853, targeted at the poor and the working class, it sparked a mass opposition movement.How did a Gloucestershire country surgeon become known as the father of vaccination? Why did the British government introduce compulsory smallpox vaccination in 1853? What were the consequences of those who opposed it? And how was the disease finally eradicated? With Nadja Durbach, Associate Professor of History at the University of Utah, Chris Dye, Co-ordinator of the World Health Organisation's work on tuberculosis epidemiology, Sanjoy Bhattacharya, Lecturer in the Wellcome Trust Centre for the History of Medicine at UCL
Melvyn Bragg and guests discuss the astonishing productivity of the Chinese Golden Age. 400 BC to 200 AD is known as the Axial Age, when great civilisations in Asia and the Mediterranean forged the ideas that dominated the next two thousand years. In China the equivalent to the Golden Age in Greece was the Warring States Period. It was a time of political turmoil, economic change and intellectual ferment that laid the foundations for the first Chinese Empire. Astronomy was systematised, the principles of Yin and Yang were invented, Confucianism grew and Taoism emerged, as a hundred schools of thought are reputed to have vied for the patronage of rival kings.Why was a period of war such a fertile age for culture and thought, what kinds of ideas were developed and how do they still inform the thinking of nearly a fifth of the world's population?With Dr Chris Cullen, Director of the Needham Research Institute at Cambridge University; Dr Vivienne Lo, Lecturer at the Wellcome Trust Centre for the History of Medicine; Carol Michaelson, Assistant Keeper of Chinese Art in the Department of Oriental Antiquities at the British Museum.
Melvyn Bragg and guests discuss the astonishing productivity of the Chinese Golden Age. 400 BC to 200 AD is known as the Axial Age, when great civilisations in Asia and the Mediterranean forged the ideas that dominated the next two thousand years. In China the equivalent to the Golden Age in Greece was the Warring States Period. It was a time of political turmoil, economic change and intellectual ferment that laid the foundations for the first Chinese Empire. Astronomy was systematised, the principles of Yin and Yang were invented, Confucianism grew and Taoism emerged, as a hundred schools of thought are reputed to have vied for the patronage of rival kings.Why was a period of war such a fertile age for culture and thought, what kinds of ideas were developed and how do they still inform the thinking of nearly a fifth of the world’s population?With Dr Chris Cullen, Director of the Needham Research Institute at Cambridge University; Dr Vivienne Lo, Lecturer at the Wellcome Trust Centre for the History of Medicine; Carol Michaelson, Assistant Keeper of Chinese Art in the Department of Oriental Antiquities at the British Museum.
Melvyn Bragg and guests discuss blood. For more than 1500 years popular imagination, western science and the Christian Church colluded in a belief that blood was the link between the human and the divine. The Greek physician, Galen, declared that it was blood that contained the force of life and linked the body to the soul, the Christian Church established The Eucharist – the taking of the body and blood of Christ. In our blood was our individuality, it was thought, our essence and our blood lines were special. Transfusion threatened all that and now itself is being questioned.Why is it that blood was used to define both man and messiah? And how has the tradition of blood in religious thought been affected by the progress of medicine?With Miri Rubin, Professor of European History at Queen Mary, University of London; Dr Anne Hardy, Reader in the History of Medicine at the Wellcome Trust Centre for the History of Medicine at University College London; Jonathan Sawday, Professor of English Studies at the University of Strathclyde.
Melvyn Bragg and guests discuss blood. For more than 1500 years popular imagination, western science and the Christian Church colluded in a belief that blood was the link between the human and the divine. The Greek physician, Galen, declared that it was blood that contained the force of life and linked the body to the soul, the Christian Church established The Eucharist – the taking of the body and blood of Christ. In our blood was our individuality, it was thought, our essence and our blood lines were special. Transfusion threatened all that and now itself is being questioned.Why is it that blood was used to define both man and messiah? And how has the tradition of blood in religious thought been affected by the progress of medicine?With Miri Rubin, Professor of European History at Queen Mary, University of London; Dr Anne Hardy, Reader in the History of Medicine at the Wellcome Trust Centre for the History of Medicine at University College London; Jonathan Sawday, Professor of English Studies at the University of Strathclyde.
Melvyn Bragg and guests discuss blood. For more than 1500 years popular imagination, western science and the Christian Church colluded in a belief that blood was the link between the human and the divine. The Greek physician, Galen, declared that it was blood that contained the force of life and linked the body to the soul, the Christian Church established The Eucharist – the taking of the body and blood of Christ. In our blood was our individuality, it was thought, our essence and our blood lines were special. Transfusion threatened all that and now itself is being questioned.Why is it that blood was used to define both man and messiah? And how has the tradition of blood in religious thought been affected by the progress of medicine?With Miri Rubin, Professor of European History at Queen Mary, University of London; Dr Anne Hardy, Reader in the History of Medicine at the Wellcome Trust Centre for the History of Medicine at University College London; Jonathan Sawday, Professor of English Studies at the University of Strathclyde.
Melvyn Bragg and guests discuss man and disease. The Book of Exodus makes clear that when God wants to strike humankind, he does so with plague and disease. For millennia epidemics were understood exactly that way - as acts of divine retribution, a force of nature that could devastate empires and annihilate great swathes of population at a stroke. From the bubonic plague to measles, from cholera to smallpox, epidemics have constantly reshaped our world, leaving destruction and huge social upheaval in their wake. Before advanced science, what defences did humankind have? How much did the ancient Greeks understand of the root causes of disease - or did they simply explain it as an imbalance of the four humours that governed the body? What were the social and political consequences of The Black Death of 14th century Europe which wiped out a third of the population? How did the scientific breakthroughs of the 19th century - and the discovery of germ theory - alter people's perception of disease? And is it possible to live in a disease free society? How have we understood these afflictions, how have we fought against them and is it a war we can ever win?With Dr Anne Hardy, Reader in the History of Medicine at the Wellcome Trust Centre at University College London; David Bradley, Professor of Tropical Hygiene at the London School of Hygiene and Tropical Medicine; Dr Chris Dye, epidemiologist with the World Health Organisation.
Melvyn Bragg and guests discuss man and disease. The Book of Exodus makes clear that when God wants to strike humankind, he does so with plague and disease. For millennia epidemics were understood exactly that way - as acts of divine retribution, a force of nature that could devastate empires and annihilate great swathes of population at a stroke. From the bubonic plague to measles, from cholera to smallpox, epidemics have constantly reshaped our world, leaving destruction and huge social upheaval in their wake. Before advanced science, what defences did humankind have? How much did the ancient Greeks understand of the root causes of disease - or did they simply explain it as an imbalance of the four humours that governed the body? What were the social and political consequences of The Black Death of 14th century Europe which wiped out a third of the population? How did the scientific breakthroughs of the 19th century - and the discovery of germ theory - alter people's perception of disease? And is it possible to live in a disease free society? How have we understood these afflictions, how have we fought against them and is it a war we can ever win?With Dr Anne Hardy, Reader in the History of Medicine at the Wellcome Trust Centre at University College London; David Bradley, Professor of Tropical Hygiene at the London School of Hygiene and Tropical Medicine; Dr Chris Dye, epidemiologist with the World Health Organisation.
Melvyn Bragg and guests discuss the Enlightenment. In Germany it's called Aufklarung, in France it's the Siecle De Lumieres, and in Britain it's called the Age of Enlightenment. It's the period around the eighteenth century when an intellectual movement committed to science and opposed to superstition, embraced the greatest minds of Europe and America; Descartes, Kant, Leibniz, Montesquie, Diderot, Voltaire, Thomas Jefferson, Benjamin Franklin. But where are all the British thinkers? According to the Encyclopaedia Britannica, 'ideas concerning God, reason, nature and man were synthesised into a world view that gained wide assent and that instigated revolutionary developments in art, philosophy and politics'. Some historians in the past have claimed that The Enlightenment passed these islands by, but in his new book Enlightenment: Britain and The Creation of The Modern World, Roy Porter says The Enlightenment was British first, and that the modern world started here. With Roy Porter, Professor in the Social History of Medicine, Wellcome Trust Centre of University College London, Linda Colley, Leverhulme Research Professor and School Professor of History, London School of Economics; Jeremy Black, Professor of History at Exeter University.
Melvyn Bragg and guests discuss the Enlightenment. In Germany it's called Aufklarung, in France it's the Siecle De Lumieres, and in Britain it's called the Age of Enlightenment. It's the period around the eighteenth century when an intellectual movement committed to science and opposed to superstition, embraced the greatest minds of Europe and America; Descartes, Kant, Leibniz, Montesquie, Diderot, Voltaire, Thomas Jefferson, Benjamin Franklin. But where are all the British thinkers? According to the Encyclopaedia Britannica, 'ideas concerning God, reason, nature and man were synthesised into a world view that gained wide assent and that instigated revolutionary developments in art, philosophy and politics'. Some historians in the past have claimed that The Enlightenment passed these islands by, but in his new book Enlightenment: Britain and The Creation of The Modern World, Roy Porter says The Enlightenment was British first, and that the modern world started here. With Roy Porter, Professor in the Social History of Medicine, Wellcome Trust Centre of University College London, Linda Colley, Leverhulme Research Professor and School Professor of History, London School of Economics; Jeremy Black, Professor of History at Exeter University.
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