Cellular catabolic process in which cells digest parts of their own cytoplasm
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RESOURCES- Join me in Lotus Rising Premium Coaching at danettecoaching.com - If you want to use the same 5 day fasting program I did, here's the link (you can get a 15% discount if you use my link): https://prolonlife.com/DANETTE - Fuel your day with Rootz Nutrition Protein Superfood: a clean protein plus greens blend designed to support energy, curb cravings, and nourish your body with real superfoods.Click this link to get your exclusive discount and try it for yourself.CONNECT WITH DANETTEInstagram: @thedanettemayFacebook: Danette MayTikTok: @thedanettemayNEW TV Show on Youtube: @TheDanetteMayListen to The Danette May ShowRead my book: danettemay.com/embraceabundancebookGet The Rise book: therisebook.comWork with Danette: danettemay.comIn this final episode of the Diary Series, I share my full 5 day fast results and what truly happened during my extended fasting experience. What began as a 5 day fast for autophagy, caffeine detox, and nervous system healing became a powerful emotional and spiritual reset. I walk through the physical symptoms, ketosis, hanger moments, and the unexpected clarity that emerged by day four and five. If you are curious about extended fasting for women, the benefits of autophagy, or what actually happens during a 5 day fast, this episode offers a transparent and personal breakdown.I also share how to break a fast safely after 5 days, what I ate first, and why proper refeeding matters for metabolism and hormonal balance. Beyond the physical benefits of fasting, this conversation explores emotional detox, spiritual connection, and the clarity that can come from clearing the body and calming the nervous system. If you are considering a 5 day fast or looking for a reset in your health and energy, this episode will give you real insight into the process and the transformation that followed. IN THIS EPISODE:(0:48) My final day check in and how you can support the show(1:34) What is coming next in 2026 astrology, grief, and powerful conversations(2:24) My go to superfood shake for busy healing days(3:43) I completed a 5 day fast and here is why I did it(4:51) Day 3 was the hardest hunger, emotions, and ketosis breath(6:28) Day 4 everything shifted tears, ritual, and deep spiritual clarity(8:04) Day 5 connection gratitude, intuition, and feeling my loved ones near(8:40) How I fasted safely, autophagy, and what you should know(11:37) How I broke my 5 day fast safely and what I ate...
In this episode of Keeping Your Breast, Dr. Jenn Simmons talks with Loren Lockman, a longtime health coach and water-only fasting expert who has supervised fasts since 1996. Loren shares how fasting helped him recover from years of chronic illness and explains what the body is doing during a properly supported water fast - especially autophagy, fasting ketosis, and deep cellular repair.They also dig into why Loren believes most people are chronically dehydrated, why he does not recommend juicing (even at home), how fasting can support healing across many conditions (including breast cancer support), and why the real key is not doing more - it is getting out of the body's way with rest, simplicity, and a structured refeed.What You'll LearnWhat water-only fasting is, how it works, and why proper supervision mattersHow fasting activates autophagy and supports deep cellular cleanupThe difference between fasting ketosis and the ketogenic dietHow detoxification and immune function are connected to chronic diseaseThe influence of the pharmaceutical industry on modern nutrition and health narrativesNatural diet and lifestyle strategies that support longevityPlant-based nutrition, protein myths, and whole-food sourcingWhy hydration, electrolyte balance, and water intake are critical during fastingWho should not fast (and who typically can)Episode Timeline:01:03 Meet Loren Lockman: 38-Year Vegan & Water-Only Fasting Expert03:13 From Chronic Illness to Radical Healing09:22 Why Conventional Medicine Failed Him16:00 Healing Is a Biological Process (Not a Prescription)21:30 What Happens in the Body During a Water Fast26:30 Fasting & Cancer: Autophagy, Immunity, and Detox31:00 Processed Foods, Pharma Influence & Modern Disease33:45 Protein Myths, Juicing, and Nutritional Controversy46:45 The Science of Autophagy & Fasting Ketosis55:45 Chronic Dehydration, Intestinal Health & Aging58:45 Can Everyone Fast? Who Should (and Shouldn't)01:04:30 Supplements: Helpful or Harmful?01:08:00 Real Client Transformations (Blood Pressure, Diabetes, Cancer)01:11:00 What It's Like to Work with Loren (Structure, Data, Refeeding)01:14:30 Why Rest Is Essential During Fasting01:23:30 Final Takeaways: Doing Less to Heal MoreTo talk to a member of Dr. Jenn's team and learn more about working privately with Dr. Jenn visit: https://calendly.com/stephanie-1031/clarity-callTo get your copy of Dr. Jenn's book, The Smart Woman's Guide to Breast Cancer, visit: https://tinyurl.com/SmartWomansBreastCancerGuideTo purchase the auria breast cancer screening test go here https://auria.care/ and use the code DRJENN20 for 20% Off.Connect with Dr. Jenn:Website: https://www.jennsimmonsmd.com/Facebook: https://www.facebook.com/DrJennSimmonsInstagram: https://www.instagram.com/drjennsimmons/YouTube: https://www.youtube.com/@dr.jennsimmons
RESOURCES- Our winner for the $150 Visa Gift Card is Dorothy Zimmers! We will contact you in order to receive the gift.- Get my 3 Day Detox here https://danettemay.com/detoxnow- If you want to use the same 5 day fasting program I did, here's the link (you can get a 15% discount if you use my link): https://prolonlife.com/DANETTE - Struggling with hair shedding or slow growth? Try Liposomal Hair Renewal with AnaGain Nu for fuller, healthier-looking hair. Exclusive offer for The Danette May Show listeners at renewyourhair.com/danettemayDewskin Instagram:https://www.instagram.com/dewskindenverDewskin Website: https://dewskindenver.com/Dewskin Shopify Product Store:https://dewskin.shopCONNECT WITH DANETTEInstagram: @thedanettemayFacebook: Danette MayTikTok: @thedanettemayNEW TV Show on Youtube: @TheDanetteMayListen to The Danette May ShowRead my book: danettemay.com/embraceabundancebookGet The Rise book: therisebook.comWork with Danette: danettemay.comIn Day 6 of my diary series, I share what it has been like to step into a 5 day fast for autophagy and cellular renewal while quitting coffee and moving through a glutathione facial peel during a time of deep personal and collective change. After two recent shootings in my small mountain town, one at the local high school and another at the rec center, I felt called inward. In this episode, I open up about my childhood experience with Mormon fasting, the shame I carried around breaking a fast, and why I avoided fasting for years even though I understood the health benefits of detox, prayer, and intentional restriction.I also talk about how I am supporting my body safely with electrolytes, minerals, and a low calorie approach to help stimulate autophagy, along with what I am noticing from caffeine withdrawal, energy shifts, and sleep changes. More than anything, this episode is about nervous system regulation, spiritual fasting, resilience after trauma, and choosing love when the world feels upside down. If you are walking through your own healing journey, detox, spiritual reset, or simply
Reflections on the Peter Attia/Epstein scandal; How to lower lp(a)—does diet help? What are bio-active peptides? Could they stave off kidney disease? Scientists just tested the fittest 81-year-old in the world—here's what they found; Media erroneously report that intermittent fasting is not effective for weight loss; Sugary drinks may stoke anxiety in teens; Omega-3s support kids' reading fluency and spelling scores; Surprising study shows saturated fats not harmful to kidneys.
Care More Be Better: Social Impact, Sustainability + Regeneration Now
(Originally recorded July 28, 2024 for another podcast Corinna once hosted, Nutrition Without Compromise — shared with permission.) Aging is often framed as inevitable decline. But what if much of what we call “aging” is actually preventable disease accumulation? In this essential re-release episode, Corinna Bellizzi sits down with Michael Greger, physician, internationally recognized speaker, and founder of NutritionFacts.org. Dr. Greger's latest book, How Not to Age, builds on the groundbreaking work of How Not to Die and How Not to Diet — translating peer-reviewed science into practical guidance for living longer and healthier. In this conversation, we explore: The difference between lifespan and healthspan Why excess protein may accelerate aging pathways The myth of “incomplete” plant proteins Fish consumption, pollution, and algae-based Omega-3 alternatives Autophagy, spermidine, and cellular repair The role of vitamin B12, vitamin D, and DHA The promise of lifestyle medicine in addressing Alzheimer's and chronic disease This episode launches a curated Care More Be Better re-share series highlighting foundational health conversations that remain deeply relevant today. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
This week on The Audit Podcast, our guest is William Englehaupt, CEO and founder of Autophagy and former director at KPMG. Bill shares his perspective on bringing discipline, structure, and consistency to audits by applying Lean and Six Sigma principles to the audit process. Drawing on his experience working with hundreds of audit teams across large public accounting firms, he explains why audits should be treated as standard work and how reducing variation in execution can dramatically improve outcomes for both auditors and clients. We talk about innovative audit methods, real-world client success stories, and why managing audits with urgency and control matters more than relying on theory or hoping things come together. Bill also walks through key ideas from his book, Managing the Hell Out of Your Audit, including the importance of upfront coaching and certifying staff before work begins to reduce rework, review notes, and frustration across audit teams Be sure to connect with Bill on LinkedIn. Also, be sure to follow us on our social media accounts on LinkedIn, Instagram, and TikTok. Also be sure to sign up for The Audit Podcast newsletter and to check the full video interview on The Audit Podcast YouTube channel. Timecodes: 2:52 - Bills BBQ 6:37 - A Favorite AI Prompt 9:45 - Innovative Approaches to Auditing 11:10 - Client Success Stories 16:53 - Bringing Discipline to New Methodologies 20:13 - Managing the Hell Out of Your Audit 23:08 - The Value of Upfront Coaching 26:40 - Final Thoughts This podcast is brought to you by Greenskies Analytics, the services firm that helps auditors leap-frog up the analytics maturity model. Their approach for launching audit analytics programs with a series of proven quick-win analytics will guarantee the results worthy of the analytics hype. Whether your audit team needs a data strategy, methodology, governance, literacy, or anything else related to audit and analytics, schedule time with Greenskies Analytics.
Why is it that we chase longevity like it's a number, yet ignore the daily behaviors that are aging us from the inside out?Most of us think longevity is about adding years. But what if it's really about removing what no longer serves you at the cellular level and at the identity level?Renee Fitton — registered dietitian, longevity specialist, and one of the leading voices in fasting-mimicking science (VP at Prolon) — breaks down the biology of renewal… and the psychology that quietly shapes our habits.Show Partners:Get your MENTAL FITNESS BLUEPRINT here! A special thanks to our mental fitness + sweat partner Sip SaunasPersonal Socrates: Better Question, Better LifeConnect with Marc: https://konect.to/marcchampagneTimestamps:00:00 — The question that opens every interview: “Who are you?”03:00 — Perfectionism, ambition, and living in the imperfect07:00 — Personality tests, self-work, and using tools like ChatGPT for reflection11:00 — Preparing for the Hoffman Process: deep psychological self-work15:00 — How to prepare your body for intense personal growth16:00 — Alcohol, sleep, and energy management before a retreat18:00 — Why plant-based nutrition supports repair and rejuvenation21:00 — Growth mode vs repair mode: the biology behind it23:00 — Autophagy explained: your body's cellular vacuum cleaner25:00 — What is the fasting mimicking diet?29:00 — Why prolonged fasting (3+ days) activates deep repair31:00 — The mental shifts that happen during fasting33:00 — Behavior change, food psychology, and identity34:00 — Type 2 diabetes study: self-initiated behavior transformation37:00 — Why five days can change your long-term habits39:00 — Why water-only fasting feels harder41:00 — How often should you fast for longevity?44:00 — Gratitude journaling as a daily mental fitness tool46:00 — The power of daily movement for emotional regulation47:00 — Renewal at the cellular and personal level*Special props
A2 THE SHOW #600 Our next guest on A2 THE SHOW is Benoit Malige — writer of The Simulation Strategists, a newsletter exploring the idea that our brains are reality-modeling processors and that mastering life means understanding the “rules of the game.”In this episode, Benoit shares his journey of redefining success, reshaping identity, and embracing discomfort as a path to growth. We dive into burnout, overthinking, entrepreneurship, habits, confidence, and how writing becomes a powerful tool for self-discovery. From questioning dictatorship and morality to overcoming perfectionism through publishing, this conversation challenges how we see ourselves — and how we choose to live.⭐IG: @benoit.mal
Topic I: Fasting: What Autophagy Can Teach Us This Ramadan Guests: Dr Viktor Korolchuk Ms Elena Rolt Ms Mays Al Ali Topic II: Birth of a Reformer: Lessons From the Early Life of the Promised Messiah (as) Producer(s): Fatima Danayal and Wafa'a Selby Trainee / Assistant Trainee Producer(s): Lead Producer: Nergis Nasir Sahiba Researchers: Afia Kassama, Tehreem Zafar and Ayela Munir Presenters: Waleed Ahmad and Shazaib Nayyer
A2 THE SHOW #599Our next guest on A2 THE SHOW is Arash Azizi — writer, historian, and contributing voice at The Atlantic. With deep insight into Iran and the wider Middle East, Arash joins us to unpack the roots of Iran's ongoing protests, economic pressures under sanctions, and the struggle for genuine sovereignty and democratic transition. We dive into Iran's regional influence, shifting diplomacy, public resistance to violence and war, and the vital role of non-violent leadership. The conversation also explores cultural power — from Iranian cinema and Panahi's Oscar nomination to how art reflects political reality — offering a grounded, human view of Iran's uncertain future.⭐ WEBSITE: https://arashazizi.com/⭐ IG: @arashaziziii
This episode is a research round up! We are discussing three new (ish) studies and reviews on nutrition, strength training, and a study that helped us change our mind! Nutrition: The effect of fasting or calorie restriction on autophagy induction: A review of the literature Strength Training: Muscular Adaptations in Single-Set Resistance Training Performed to Failure or with Repetitions-in-Reserve Changed our Minds: The Sweet Tooth Trial
The Real Truth About Health Free 17 Day Live Online Conference Podcast
Drs. Barker and Goldhamer explain fasting supervision, screening, mental readiness, and safe durations for chronic conditions. #WaterFasting #SupervisedFasting #FastingSafety #ChronicHealing
In this episode, we dive deep into how the Metabolic Trinity actually works to heal your cells. You'll learn about the two ways your body clears out trash and why dry fasting activates a special "emergency" path for deep cleaning that water fasting can't reach. We also explain "metabolic hibernation"—why your internal energy drops during chronic illness and why T3 therapy is required to power your recovery. Finally, we look at how dry fasting can boost immune cell efficiency by 54% and how growth hormone signals your body to rebuild. We show why doing just one or two pillars isn't enough to beat chronic illness and why sequence is everything.**Scientific References:*** *Hyperosmotic Stress Induces Unconventional Autophagy Independent of the Ulk1 Complex* - Proving the fast "backdoor" cleaning path used in dry fasting.* *Dynamics of Basal Metabolic Rate During Absolute (Dry) Fasting* - Showing how the body saves energy (14%) and why tissue-level testing is more accurate than blood tests.* *Dry Fasting and the Immune System* (Khoroshilov) - Documenting the dramatic increase in immune strength and killing efficiency during dry fasting (+54% NK cell boost).**Helpful Resources:*** Dry Fasting Club: https://dryfastingclub.com* The Scorch Protocol Hub: https://dry-fasting-club.github.io/scorch-protocol/index.html**Medical Disclaimer:**The content in this video is for educational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have heard in this video.
The Real Truth About Health Free 17 Day Live Online Conference Podcast
Dr. Goldhamer introduces water-only fasting, autophagy, visceral fat loss, and detoxification benefits—all grounded in over 50 years of clinical data. #WaterFasting #DetoxScience #Longevity #HealthTalks
A2 THE SHOW #598Next on A2 THE SHOW, we sit down with Brad Rohrs, a luxury real estate expert with over 20 years of experience in residential and commercial markets and more than $170 million in closed transactions. A two-time Best of Zillow Award winner in the DC Metro area, Brad goes beyond the headlines to break down real estate trends, economic inequality, homeownership vs. renting, and how the financial system really impacts wealth, well-being, and the so-called American Dream. From mortgage negotiations and social media myths to systemic barriers and global investing, this conversation challenges everything you think you know about money and property.⭐Website: https://www.rohrsteam.com/⭐IG: @rohrsteam
In this episode, Dr. David Jockers dives into the benefits of the Protein Sparing Modified Fast, a powerful tool for burning fat, especially visceral fat. He explains how this strategy promotes fat loss while preserving lean muscle mass, even with a calorie-restricted diet. Dr. Jockers shares how fasting triggers autophagy and the role it plays in cellular rejuvenation, helping the body break down old, damaged mitochondria and replace them with healthier ones. He also discusses how protein-sparing fasting impacts insulin sensitivity, brain function, and overall resilience, while offering practical tips for implementing this approach into your lifestyle. In This Episode: 00:00 Introduction to Fasting and Its Historical Context 00:48 Protein Sparing Modified Fast Explained 06:57 Dr. Jockers' Journey into Holistic Health 12:45 Introduction to Fasting Practices 14:20 Personal Fasting Experience and Benefits 17:32 Intermittent Fasting and Its Popularization 27:20 Autophagy and Cellular Rejuvenation 36:21 Challenges of Extended Fasting 37:13 Introduction to Protein Sparing Modified Fast 37:54 Benefits and Guidelines of Protein Sparing Modified Fast 40:35 Practical Tips for Protein Sparing Modified Fast 45:15 Addressing Common Concerns About Fasting 48:53 The Role of Ketones in Brain Health 54:42 Spiritual and Physical Benefits of Fasting 56:42 Autophagy and Protein Sparing Modified Fast 01:03:33 Tips for Enhancing Insulin Sensitivity 01:06:20 Favorite Meals and Desserts 01:08:31 Concluding Thoughts and Favorite Bible Verse If you want practical, natural strategies to balance your hormones, heal your gut, boost your energy, and slow aging, don't miss The Dr. Josh Axe Show. Dr. Axe blends ancient wisdom with cutting-edge science and brings on world-class experts for unfiltered conversations you won't hear anywhere else. Transform your health from the inside out and subscribe to The Dr. Josh Axe Show, with new episodes every Monday and Thursday. If you're looking to boost your health naturally, Paleo Valley's Super Greens powder is a game-changer. Packed with 23 organic superfoods, it provides all the nutrients your body needs for boundless energy and vitality, without the digestive issues that come with cereal grasses. For 15% off, visit paleovalley.com/jockers and use code JOCKERS at checkout. When it comes to cooking, Chef Foundry offers the perfect solution with their P 600 ceramic cookware, which is free from Teflon, PFAS, and plastic coatings. Made with Swiss-engineered ceramic, this cookware makes it easy to prepare healthy meals without the toxins. Take 20% off with code SAFE20 at chefsfoundry.com/jockers and upgrade your kitchen today. "Protein Sparing Modified Fast helps quench satiety, and most people on it don't feel as hungry or have cravings." Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio Resources: Visit paleovalley.com/jockers for 15% off with code JOCKERS. Visit chefsfoundry.com/jockers for 20% off with code SAFE20. Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/
Our next guest on A2 THE SHOW is Renee Fitton, MS, RD—a leading dietitian and entrepreneur working at the intersection of nutrition, healthcare, and education. As Director of Education & Healthcare Sales at ProLon (L-Nutra), Renee helps shape evidence-based strategies around fasting-mimicking diets and personalized nutrition. In this conversation, she breaks down different fasting methods, the science behind autophagy and biological age, and why personalization matters—from intermittent fasting timing and creatine use to fiber, GLP-1s, and intuitive eating. With a background that includes co-founding Heali AI and building large-scale nutrition programs, Renee brings practical, science-driven insights into how we eat, fast, and make healthier choices in a complex modern food landscape.⭐IG: @fittonnutrition
Confused by alkaline water, juice cleanses, water fasting, or detox trends? You're not alone.In this episode, Dr. Paula Ruffin breaks down the science of detoxification, metabolism, digestion, and hydration—and explains why most detox trends fail.Key Takeaways• Blood pH is tightly regulated; food and water do not directly alkalize the body• It's not the pH of what you consume—it's how your body metabolizes it• Lemons are acidic going in but alkaline-forming after digestion• Alkaline water can interfere with digestion in people with low stomach acid• Hydrogen and “structured” water do not activate liver detox pathways• Drinking large amounts of water with meals can dilute digestion• Juice cleanses reduce intake but do not support liver detoxification• Autophagy increases with fasting, but detox and healing require nutrientsWhat Real Detox Looks LikeTrue detoxification depends on:• Liver Phase I & II support• Amino acids, minerals, and fiber• Healthy digestion and bile flowThis is why nutrient-supported detox protocols—like UltraClear Renew—work better than starvation, fasting, or water-based detoxes.Bottom LineHealth doesn't come from hacks or extremes.It comes from supporting the body's natural detox and metabolic systems.STAY CONNECTED!Free resources:https://drruffin.com/ / drpaularuffin / drpaularuffin / newhudsonchiropracticandwellnesscenter / drpaularuffin For high quality supplements:https://us.fullscript.com/welcome/pru...
In this episode of the Metabolic Freedom Podcast, Ben Azadi reveals how using one tablespoon of high-quality extra virgin olive oil during a fast can enhance fat loss, autophagy, insulin sensitivity, and cortisol balance instead of breaking your fast. Ben explains why fasting is not about zero calories, but about hormonal signaling, and how the right olive oil sends a powerful “fat-burning and healing” message to the body. You'll learn: Why olive oil does not break a fast and actually enhances autophagy How extra virgin olive oil activates fat-burning genes (PPAR-alpha) The role of olive oil in lowering insulin and cortisol Why high-polyphenol olive oil matters and most grocery store oils fail A simple daily olive oil fasting protocol for metabolic health How olive oil fasting can be gentler and more effective than water fasting The truth about cooking with olive oil vs seed oils Ben also breaks down how to identify real, high-quality olive oil, why polyphenols are the key compound for fat loss and inflammation reduction, and how this simple protocol can lead to better energy, reduced belly fat, and impro FREE GUIDE: Lose 10 Pounds in 7 Days - https://bit.ly/4sjMvfZ
What are your thoughts on Alpha-ketoglutarate for healthy aging?A treatment for warts?Am I destined to develop diabetes given my strong family history of diabetes and high blood pressure?
Consequences of weight loss with weight loss drugs...Enter myostatin inhibitor drugsMy latest HgbA1c is 5.9, and I'm doing everything right. What gives?I'm approaching 80. Could you discuss aging?
This episode features a conversation with Melanie Murphy Richter, MS, RDN, who discusses the benefits and science behind the Prolon fasting program. Melanie explains the concept of fasting and its evolutionary benefits, emphasizing the role of autophagy—a cellular rejuvenation process activated by fasting. The discussion covers the Prolon fasting-mimicking diet (FMD), which allows for some food intake while still achieving fasting benefits. Melanie details the physiological changes during the five-day Prolon fast, including ketosis and autophagy, and stresses the importance of transitioning out of the fast carefully to maintain benefits. The episode also touches on the extensive research supporting Prolon's efficacy, including its impact on longevity and metabolic health.Product Discount Codes + Links2025 Holistic Holiday Gift Guide: HereHerbal Face Food: Website (Discount Code: LAL30)Prolon Fast-Mimicking Program: Website (Discount Link Gives 25% off) Healing Alchemy Membership: Learn MoreGuest InfoMelanie Murphy Richter - WebsiteMelanie Murphy Richter - InstagramRelated EpisodesPodcast Ep. 212: Kim Ressler - Revolutionizing Health: Custom Supplements Tailored to Your DNAPodcast Ep. 192: Keelia Ryan - Sacred Plant MedicineWork w/Leigh AnnLearn: What is EVOX Therapy?Book: Schedule a Session or FREE Discovery CallMembership: What is The Healing Alchemy MembershipConnect w/Me & Learn MoreWebsiteInstagramTiktok
Neil steps away from traditional business tactics to focus on the essential foundation of any successful venture: the health and well-being of the entrepreneur. He explores the concept of ‘The Fasting Miracle', specifically focusing on water fasting and its transformative effects on the body and mind. He breaks down the biological processes that occur during various stages of fasting, from the initial fed state to deep cellular repair and regeneration. By sharing his personal 21-day fasting experience and detailing the scientifically supported benefits, such as increased mental clarity, fat loss, and immune system rebooting, Neil provides a compelling case for fasting as a no-cost tool for tutors and coaches to optimise their performance and longevity. KEY TAKEAWAYS Maintaining good health is a critical business issue because it forms the foundation for everything a business owner does. Fasting triggers natural mechanisms like lipolysis (fat burning) and ketosis, where the body switches from burning glucose to burning stored fat and ketones for cleaner, steadier energy. Between 20 to 24 hours of fasting, the body initiates autophagy - a "self-eating" process where damaged cells and proteins are recycled into useful materials, reducing inflammation and the risk of degenerative diseases. Extended fasting (72+ hours) can eliminate old white blood cells and stimulate stem cell production to create a new, more efficient immune system. BEST MOMENTS "Health is the foundation on which everything we do is built. So staying healthy is a business issue." "Fasting isn't some brand new trendy fufu-dufu woo-woo fad. People have been doing it for centuries." "Autophagy is cellular cleanup and repair. The damaged proteins and organelles that are flapping around your body are broken down and recycled into useful stuff." "BDNF supports brain health and cognitive function. I've heard BDNF often called miracle grow for the brain, and that's what it does." "The longer I fasted, the better I felt. My mental sharpness increased like it's hard to explain. I just got sharper, faster." VALUABLE RESOURCES www.Neilcowmeadow.com info@neilcowmeadow.com HOST BIO Neil Cowmeadow is a maverick peripatetic guitar teacher from Telford with over 19 years' experience in the business of helping people. Learn how to start, grow and love your business with Neil's invaluable advice and tips without the buzzwords and BS! This Podcast has been brought to you by Disruptive Media. https://disruptivemedia.co.uk/
Most conversations about longevity focus on tactics. This episode breaks down the biology underneath them. You'll hear a systems level analysis of how insulin signaling, mTOR, mitochondrial function, inflammation, and nutrient sensing interact to determine biological age, disease risk, and long term human performance. This is not surface level biohacking. It is a deep dive into the mechanisms that actually control aging, metabolism, muscle preservation, and brain optimization, and why most anti aging strategies fail when they ignore these foundations. This all-time classic episode from 2024, has host Dave Asprey joined by Mark Hyman, a practicing physician and one of the most respected leaders in functional medicine. Dr. Hyman is the founder and senior advisor of The UltraWellnessCenter, the founder and former head of strategy and innovation at the Cleveland Clinic Center for Functional Medicine, and a long time advocate for treating root causes instead of managing disease. With over 30 years of clinical experience, his work focuses on restoring mitochondrial health, optimizing metabolism, reversing chronic disease, and slowing biological aging using science backed interventions. Together, Dave and Mark dismantle common myths around protein, carnivore diets, ketosis, fasting, supplements, and longevity drugs. They explain why sugar accelerates aging faster than protein, how mTOR must cycle instead of staying suppressed, and why muscle, mitochondria, and metabolic flexibility matter more than calorie restriction. The conversation also covers nootropics, sleep optimization, neuroplasticity, AI driven diagnostics, and how functional medicine reframes aging as a reversible biological process rather than an inevitable decline. You'll learn: • How insulin and nutrient sensing control aging speed • Why mitochondria sit at the center of longevity and disease • The truth about mTOR, fasting, and protein intake • How ketosis and metabolic flexibility protect long term health • Where supplements and nootropics actually fit in brain optimization • Why functional medicine outperforms symptom based care • How AI and advanced testing are reshaping modern medicine Thank you to our sponsors! - MASA Chips | Go to https://www.masachips.com/DAVEASPREY and use code DAVEASPREY for 25% off your first order. -ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. -OneSkin | Try OneSkin for 15% off with code DAVE at https://www.oneskin.co/DAVE. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: longevity biohacking, functional medicine longevity, biological age reversal, mitochondria and aging, mTOR pathway aging, insulin resistance and aging, metabolic flexibility, fasting and longevity, ketosis and metabolism, protein intake and mTOR, muscle and longevity, inflammaging, chronic inflammation aging, mitochondrial dysfunction, nutrient sensing pathways, rapamycin longevity, metformin longevity debate, carnivore diet longevity, sugar and aging, brain optimization longevity, neuroplasticity and aging, sleep optimization biohacking, supplements for longevity, anti aging metabolism, human performance optimization, Dave Asprey longevity, Mark Hyman longevity Resources: • Mark's Website: https://drhyman.com/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 - Trailer 0:45 - Introduction 4:49 - Aging as a Treatable Disease 7:50 - The Hallmarks of Aging 14:23 - Nutrient Sensing and Longevity Switches 17:37 - Time Restricted Eating and Autophagy 20:44 - The Four Longevity Pathways 21:49 - Metformin Debate 25:30 - Ozempic and Weight Loss 28:42 - Rapamycin and mTOR 36:23 - Meat, Protein, and Aging 39:46 - Protein Quality and Muscle Synthesis 45:50 - Protein Timing for Muscle Building 48:08 - Metabolic Flexibility 51:32 - Inflammaging 55:26 - Zombie Cells and Senescence See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
What if the confusion around fasting and hormones isn't because the science is complicated, but because most people are using the wrong tools for the wrong goals? In this episode, I sit down with Dr. Mindy Pelz to get clear about what fasting actually does, when it helps, and when it backfires. This is a conversation about taking ownership of your metabolism instead of chasing trends that don't match your life. We talk about the viral moment from her Stephen Bartlett interview, how misinformation spreads, and what she learned from being at the center of it. Mindy breaks down her six core fasts, why women need a different strategy, and how to adjust your approach if you train hard. We get into cycle-based fasting, fertility, menopause, HRT, toxic load, peptides, creatine, apple cider vinegar, and the rise of GLP-1 drugs. If you've ever wondered how to use fasting without wrecking your energy or performance, this episode will give you a clearer path forward. Dr. Mindy Pelz is a bestselling author, educator, and functional health expert known as the fasting guru. Her books Fast Like a Girl and Age Like a Girl have helped millions of women rethink metabolic health, hormones, and aging, and she has led hundreds of thousands of people through community fasts that focus on real-world results, not quick fixes. What We Discuss: (00:00) How a Misquote Went Viral and Changed Mindy's Career (04:12) What the Internet Got Wrong About Testosterone and Fasting (11:19) The Biggest Fasting Mistakes Most People Still Make (17:05) The Six Core Types of Fasting and When to Use Each (23:28) Fasting for Gut Repair, Weight Loss, and Dopamine Reset (28:54) How Athletes and Active Women Should Adapt Their Fasts (34:04) Cycle-Based Fasting and Hormonal Timing for Women (43:00) Supplement Cycling, Autophagy, and Metabolic Flexibility (55:19) GLP-1 Drugs, Gut Health, and the Real Drivers of Hunger (59:31) The Long-Term Risks of Quick-Fix Weight Loss Trends (01:05:40) Fertility, Progesterone Needs, and Rethinking HRT (01:16:14) Menopause, Brain Rewiring, and Building Cognitive Strength (01:28:48) Peptides, ACV, and Final Insights Before Wrap-Up Thank you to our sponsors: Therasage: Head over to therasage.com and use code Be Bold for 15% off Air Doctor: Go to airdoctorpro.com and use promo code HUSTLE40 for up to $300 off and a 3-year warranty on air purifiers. Magic Mind: Head over to www.magicmind.com/jen and use code Jen at checkout. Momentous: Shop this link and use code Jen for 20% off Manna Vitality: Visit mannavitality.com and use code JENNIFER20 for 20% off your order Prolon: Get 30% off sitewide plus a $40 bonus gift when you subscribe to their 5-Day Program! Just visit https://prolonlife.com/JENNIFERCOHEN and use code JENNIFERCOHEN to claim your discount and your bonus gift. Amp fit is the perfect balance of tech and training, designed for people who do it all and still want to feel strong doing it. Check it out at joinamp.com/jen Find more from Jen: Website: www.jennifercohen.com Instagram: @therealjencohen Books: www.jennifercohen.com/books Speaking: www.jennifercohen.com/speaking-engagement Find more from Dr. Mindy Pelz: Website: www.drmindypelz.com Instagram: @dr.mindypelz TikTok: @drmindypelz YouTube: @drmindypelz
If you've ever felt like you need a specific diet, program, supplement, or piece of equipment to get results, this episode is for you.In today's Red Delta Project live Q&A, I break down one of the biggest “progress traps” in fitness: dependence. The more you rely on external systems, validation, products, or ideologies, the less freedom and control you actually have… and the more likely you are to stay stuck in the fitness rat race.Then we roll straight into Q&A on elbow tendonitis from high-volume pullups, building muscle at calorie maintenance, how tempo and pauses affect hypertrophy, sissy squats, shoulder pain workarounds, autophagy hype, TRT expectations, chronic injury strategy, and more.
Dr. Hoffman continues his conversation with Dr. Ross Pelton, Director of Science & Education for Essential Formulas Inc., which specializes in premium probiotic products. He's known as the Natural Pharmacist.
Exploring the Microbiome and Longevity with Dr. Ross Pelton, Director of Science & Education for Essential Formulas Inc., which specializes in premium probiotic products. He's known as the Natural Pharmacist. He details the pivotal role of the gut in chronic disease, referencing the ancient insights of Hippocrates, and explores the concept of postbiotics. The conversation touches on the influence of gut health on various organ systems, the importance of diversity in the gut microbiome, and how lifestyle choices like diet, exercise, and sleep contribute to healthy aging. They also tackle cutting-edge topics such as the implications of GLP-1 medications, anabolic resistance, and the potential benefits of rapamycin for longevity.
In this episode, we discuss David Goggins vs. rest days, stomach vacuums, autophagy, fasted training, airplanes with toddlers, and more.We hope you enjoy this episode and if you'd like to join us in The Online Fitness Business Mentorship, you can grab your seat at https://www.fitnessbusinessmentorship.comThank you!-J & MWATCH this episode on YouTube: https://youtu.be/7EuldRo6eJwTIMESTAMPS:(00:00) — Intro(00:11) — Energy & fatigue levels as we age(06:00) — The strangest (& most inconvenient) way Jordan has improved his sleep...(11:36) — Experiences & advice for traveling with small children(16:27) — Dog walking etiquette & porch pirates getting what they deserve(21:31) — Online chess, Sun Tzu, & the Art of War(24:04) — The difference between a banana and a Snickers bar(24:27) — Fasted training(26:43) — Doing exercises you hate(29:59) — Weight vest recommendations(31:15) — What are the benefits of stomach vacuums?(33:08) — Age gaps & romantic relationships(34:55) — The reality of weight spikes(36:46) — Dealing with loose skin after weight loss(39:09) — Goggins vs Rest Days(43:02) — The "best" type of creatine(47:36) — Fasting & autophagy(49:24) — The truth about fitness wearables(50:20) — Things Jordan misses about Boston(52:29) — Wrap-upFollow the show on social:YouTube - https://www.youtube.com/@personaltrainerpodcastInstagram - https://www.instagram.com/personaltrainerpodcastTikTok - https://www.tiktok.com/@personaltrainerpodcastJoin our email list & get our FREE '30 Ways To Build A Successful Online Coaching Business' manual: https://bit.ly/30O2l6pCheck out our book 'Eat It!' at https://www.amazon.com/Eat-It/dp/0008543046If you have any questions you'd like to have answered on the show, shoot us an email at info@fitnessbusinessmentorship.comIf you enjoyed the episode, we would sincerely appreciate it if you left a five-star review.----Post-Production by: David Margittai | In Post MediaWebsite: https://www.inpostmedia.comEmail: david@inpostmedia.com© 2025 Michael Vacanti & Jordan Syatt
Ashley Bizzell joins Something For Everybody this week. Ashley is a registered dietitian and certified diabetes care and education specialist with over fifteen years of experience. In this conversation, Ashley and I discuss various aspects of health and nutrition, focusing on the importance of what we stop eating, the role of metabolic health, and the significance of habit formation. We explore the fasting mimicking diet, its benefits, and how it can help improve overall health. - See discounts for all the products I use and recommend: https://everybodyspod.com/deals/ - Shop For Everybody Use code SFE10 for 10% OFF
In today's episode, I'm literally on the walking pad with a baby in the wrap while Amy's in her office and surprise guest Beth is joining us from the car - because this is real life and we always make it work. We dove into a topic that's been popping up nonstop in our communities lately: intermittent fasting, autophagy, inflammation, and all the fear-based protocols targeting women, especially menopausal and perimenopausal women. This conversation is part science, part mindset, and part “please stop overcomplicating your life.”We break down what autophagy actually is, and answer the question: is fasting the magical lever people are pulling it off as? We chat about how chronic inflammation gets twisted into a marketing scheme instead of something you can support with simple, foundational habits. Most importantly, we talk about the psychological fallout… how these rigid protocols disconnect you from your hunger cues, fuel all-or-nothing thinking, and keep you believing you're fragile, broken, or in need of secrets. Spoiler: you're not.“We are not fragile. We are not broken. We are not delicate - and you don't need a protocol to fix what was never damaged.”- Amy Rudolph“You cannot read the label when you're inside the jar - and so many women don't realize how good they could feel until they stop following rules that were never meant for them.”- Iris DeadliftsThis week on Here's the Deal: Fitness, Nutrition and Mindset for People Who Don't Want Life to Suck:What is autophagy and what does it do? How do we get it?The truth about inflammation: the difference between chronic vs. acute, and why skipping meals doesn't “heal” anythingHow fasting rules disconnect women from hunger cues and mimic disordered eating patternsWhy most clients who attempt intermittent fasting end up overeating at night and struggling with protein intakeHow “fear-based protocols” target menopausal women with misinformation, secrecy, and false authorityThe psychological toll of chasing hacks, cycle-syncing rules, and hormone micromanagementReal-life performance wins from fueling before workouts instead of training fastedThe only things that consistently support health and longevity: sleep, strength training, protein, fiber, movement, stress management—the “boring basics”Connect with Us:Iris Deadlifts on InstagramAmy Rudolph on InstagramWork with us at Beth Feraco FitnessThanks for tuning in to this week's episode of Here's the Deal: Fitness, Nutrition, and Mindset for People Who Don't Want Life to Suck, where we challenge the common understanding of what it means and what it takes to be fit and healthy! If you enjoyed this episode, don't forget to subscribe and leave a review wherever you listen to your favorite podcasts.Apple Podcasts | SpotifyBe sure to share your favorite episodes on social media and tag us!Join Iris Deadlifts on Instagram, Meri on Instagram, and Amy Rudolph on Instagram.
In this episode, Dr. Jockers and Vanessa Spina break down new human research showing why high protein doesn't block autophagy when calories are low. You'll learn how this changes everything we've believed about protein timing, fasting, and cellular repair. The conversation also reveals why prioritizing protein can accelerate fat loss without sacrificing muscle. You'll hear how protein impacts appetite, hormones, and metabolic flexibility—and why many people overeat simply because they're under-consuming essential amino acids. Vanessa explains the protein leverage effect and how it naturally reduces cravings, stabilizes blood sugar, and makes eating "effortlessly" satisfying. These insights can help you rethink how you build your daily meals. You'll discover why certain fasting styles can increase visceral fat loss, support hormonal balance, and boost performance. Expect a mix of science, real-world application, and surprising findings you may not have heard before. In This Episode: 00:00 Introduction and Exciting New Study 00:21 Welcome and Guest Introduction 00:30 Deep Dive into the New Study 01:52 Vanessa Spina's Expertise and Background 05:47 Interview with Vanessa Spina Begins 06:15 Discussion on Protein Absorption Study 14:04 Personal Experiences with Protein and Fasting 16:55 Debunking Protein Myths 18:10 Nutrition Principles and Protein Prioritization 22:23 Ketones, Satiety, and Inflammation 27:07 Balancing Hormones and Stress 31:17 Understanding Autophagy and Protein Intake 32:35 The Importance of Human Trials in Research 35:11 Study on High Protein Fasting Mimicking Diet 38:38 Results and Implications of the Study 42:18 Personal Experiences with Protein-Sparing Modified Fasting 45:32 Practical Tips for Implementing Protein-Sparing Modified Fasting 57:54 Comparing Different Fasting Approaches 01:01:13 Conclusion and Final Thoughts Hydration is one of the fastest ways to boost your energy, sharpen your focus, curb cravings, and even improve the look and feel of your skin — but water alone isn't enough. Your cells need electrolytes to actually absorb and use that hydration. Paleovalley Essential Electrolytes delivers premium, full-spectrum minerals with zero sugar, no artificial ingredients, and unprocessed sea salt, helping you feel more energized, clear-headed, and vibrant — and look more radiant from the inside out. Just one scoop a day can make a noticeable difference. Try Paleovalley Essential Electrolytes and save 15% by visiting Paleovalley.com/jockers and using code JOCKERS at checkout. I just wanna take a moment to interrupt this podcast to tell you about one of my favorite podcasts I listen to. It's called The Dr. Josh Axe Show, hosted by my good friend Dr. Josh Axe. Every week he shares how to balance your hormones, restore your gut, boost your energy, and slow aging without relying on harsh medications or quick fixes. He shares both ancient biblical practices and the latest breakthroughs in nutrition, herbal remedies, and lifestyle medicine. If you're ready to take control of your health, renew your energy, and transform your mind, body, and spirit, tune into The Dr. Josh Axe Show every Monday and Thursday wherever you get your podcasts. "Most people don't overeat because they lack willpower — they lack protein." Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio Resources: Study Referenced: https://www.researchgate.net/publication/394359134_Effects_of_fasting-mimicking_diets_with_low_and_high_protein_content_on_cardiometabolic_health_and_autophagy_A_randomized_parallel_group_study Get 15% off Paleovalley Electrolites: paleovalley.com/jockers – Use code JOCKERS Connect with Vanessa Spina: Website: ketogenicgirl.com Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/
In this episode, Ben Azadi breaks down the science and real-life experience behind a 36-hour fast, explaining why this specific fasting window creates a powerful metabolic, hormonal, and cellular reset. Ben walks listeners through the hour-by-hour stages of the fast — from digestion, to fat burning, to deep autophagy — and explains how fasting transforms the body at every level. He covers increases in human growth hormone, gut repair, ketone production, mitochondrial upgrades, and the mental clarity that comes from elevated BDNF. He also answers the most common questions about long fasts:• What drinks or supplements break a fast• Whether women should modify fasting based on their cycle• How often to repeat a 36-hour fast• What symptoms are normal vs. concerning• Whether fasting impacts muscle• How to eat before and after a long fast for best results Ben also explains who should not attempt a 36-hour fast and how to break the fast without losing the benefits. He emphasizes that fasting is not starvation — it's a biological event designed for healing, fat loss, and metabolic restoration. FREE GUIDE: The World's Easiest Breakfast Diet - https://bit.ly/4puckHV
Can natural herbs aid recovery from anorexia? What an analysis of Hitler's DNA tells us about how genes shaped his personality; Can surgical anesthesia accelerate memory loss? Bananas could be interfering with your smoothie's health benefits; Not just sun, but pesticides and herbicides increase risk for melanoma; Chemical residues on produce impair male fertility; Proliferation of fast-paced social media videos are dumbing us down; Doctors aren't less resilient, the demands of medicine are just fostering unprecedented levels of physician burnout.
Energize your life and rejuvenate at the cellular level with Mitochondriac, the ultimate mitochondrial rejuvenation supplement. Packed with powerhouse ingredients for optimal health, it's like getting the benefits of NAD in a convenient, family-friendly pill form. Dive in and transform your health journey today: https://www.mswnutrition.com/products/mitochondriac Time Stamps: 00:00 START 02:29 Mitochondrial Power 04:54 Combatting Aging 09:39 Nourishing Cells 11:34 Brain Boost 13:53 Nutritional Sources 16:12 The NAD Experience 18:35 Key to Production 21:01 Repair and Rejuvenation 23:24 The Autophagy Effect 25:49 Insulin's Role 27:51 Biogenesis Breakthrough 30:15 Resveratrol: A Synergistic Ally 32:25 Final Insights Show Notes: Nurse Doza takes listeners on an informative journey through the vital role of NAD in maintaining energy, supporting brain function, and ensuring cellular health. He emphasizes how aging leads to a natural decline in NAD levels, affecting our overall wellness. Through an exploration of how Mitochondriac can serve as an oral alternative to NAD supplementation, Doza offers actionable insights for anyone looking to enhance their health span and live a more vibrant life. He discusses Mitochondriac's role in supporting mitochondrial function, thereby promoting longevity and vitality. URLs for References: School of Doza Sign-up: https://schoolofdoza.com/sign-up Importance of NAD: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442590/ Supporting Brain Health: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787556/ Cellular Repair and Autophagy: https://www.cell.com/developmental-cell/fulltext/S1534-5807(22)00760-2The Power of Resveratrol: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342515/ Discover the secret to youthful energy and cellular health with Mitochondriac, your daily dose of mitochondrial rejuvenation. This powerhouse supplement is designed to replicate the effects of NAD supplementation, supporting your health from the cellular level up. Begin your journey towards a more energetic, vibrant life now:https://www.mswnutrition.com/products/mitochondriac
Nutritionist Leyla Muedin focuses on a new perspective in Alzheimer's research, particularly the role of microglial cells. She reveals insights from integrative neurologist Dr. David Perlmutter's presentation at the Integrative Healthcare Symposium, emphasizing the significance of microglial cells in Alzheimer's disease. The discussion highlights the traditional focus on beta amyloid plaques and introduces the importance of shifting from the M1 pro-inflammatory phenotype to the M2 anti-inflammatory phenotype of microglial cells. Dr. Perlmutter advocates for addressing systemic metabolic and inflammatory issues, pointing out factors like poor diet, lack of sleep, and high blood sugar, which are crucial in preventing Alzheimer's. The episode delves into lifestyle interventions such as ketogenic diets, fasting, and nutritional impacts to manage and potentially reverse the detrimental shift in microglial behavior.
In this episode, Dr. David Jockers joins Ben Azadi to break down what really happens inside your body during a 72-hour fast — from burning stored fat to reducing inflammation in the brain. Together, they explore how fasting resets dopamine, boosts mental clarity, and strengthens emotional resilience while tapping into your body's innate healing power. You'll hear Dr. Jockers and Ben discuss how autophagy clears out old, damaged cells and replaces them with stronger, more stress-resilient ones. They also dive into how fasting triggers the creation of new mitochondria — your body's energy factories — helping you burn fat more efficiently and age more gracefully. Finally, discover how fasting boosts growth hormone and resets your immune system, leading to greater energy, sharper focus, and improved longevity. Whether you're new to fasting or ready to take it to the next level, this episode reveals the science and strategy behind one of nature's most powerful healing tools. In This Episode: 00:00 Introduction to Sacrifice and Dopamine 04:45 The Science of Fasting: 12 to 24 Hours 14:27 Autophagy and Metabolic Health 16:41 Air Quality and Autophagy Explained 28:29 Preparing for a Successful Fast 34:19 Understanding Cravings During Fasting 34:30 Timing Fasting with Menstrual Cycles 34:53 Managing Hunger and Ghrelin 36:03 Benefits of Extended Fasting 36:37 Fat Burning and Liver Health 38:41 Fasting and Intestinal Health 42:00 Dopamine Reset and Fasting 48:15 Supplements and Liquids During Fasting 54:59 Breaking the Fast and Refeeding 58:03 Gratitude and Final Thoughts Hydration is one of the fastest ways to boost your energy, sharpen your focus, curb cravings, and even improve the look and feel of your skin — but water alone isn't enough. Your cells need electrolytes to actually absorb and use that hydration. Paleovalley Essential Electrolytes delivers premium, full-spectrum minerals with zero sugar, no artificial ingredients, and unprocessed sea salt, helping you feel more energized, clear-headed, and vibrant — and look more radiant from the inside out. Just one scoop a day can make a noticeable difference. Try Paleovalley Essential Electrolytes and save 15% by visiting Paleovalley.com/jockers and using code JOCKERS at checkout. Breathe cleaner, healthier air at home with AirDoctor, the award-winning air purifier that eliminates up to 99.99% of airborne contaminants — including allergens, mold spores, and viruses. It's the same purifier trusted by top wellness experts for a reason. Visit AirDoctorPro.com and use promo code NUTRITION to get up to $300 off plus a free 3-year warranty. Breathe easier and protect what matters most. "By tapping into body fat and producing ketones, your brain can function more clearly and reduce inflammation." Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio Resources: Get 15% off Paleovalley Electrolites: paleovalley.com/jockers – Use code JOCKERS Visit AirDoctorPro.com and use code NUTRITION for up to $300 off plus a free 3-year warranty. Connect with Ben Azadi: Website: https://www.benazadi.com/ Book: https://amzn.to/41O02jk Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/
What really happens when you drink only water for 24 hours? In this episode, Ben Azadi breaks down the powerful science behind fasting and how it can help heal a fatty liver, reduce inflammation, and reignite your body's natural fat-burning ability. You'll learn: Why constant snacking keeps your liver in “storage mode” The hour-by-hour breakdown of a 24-hour water fast How fasting triggers autophagy, your body's internal cleanup system The natural surge in human growth hormone that supports fat loss and longevity Exactly how to prepare for, complete, and break your fast safely Plus, Ben shares a free 7-day fat loss protocol to help you reset your metabolism and burn one pound of fat per day — without counting calories or overtraining.
Is your child struggling with ADHD, allergies, or chronic illness? Wondering why childhood health is declining despite modern medicine?In this episode, functional medicine doctor Dr. Dusty Hess explains the root causes behind rising rates of ADHD, autism, and infertility—and shares practical solutions every family can implement today.What You'll Learn: ✅ Functional medicine vs. conventional healthcare (firefighters vs. builders) ✅ How plastics, seed oils, and processed foods disrupt hormones ✅ The truth about vaccines and personalized health approaches ✅ Why inflammation is both friend and foe ✅ The shocking infertility crisis: sperm counts down 50% in 50 years ✅ Autophagy and intermittent fasting made simple ✅ Practical swaps for your kitchen, home, and daily routine ✅ Why homeschool families are uniquely positioned for better healthAbout Dr. Dusty Hess: Dr. Dusty is a functional medicine doctor, founder of Upstream Health, and creator of Upstream Magazine—a monthly publication helping Christian families get healthy from the inside out.Resources: Explore everything Upstream Health has to offer at www.upstreamhealth.comOur free ADHD webinar shares guidance, tools, and encouragement from our care team to support you or someone you love navigating ADHD. https://upstreamhealth.com/webinar-landing/Upstream Health link-tree: https://upstreamhealth.com/link-tree/ Perfect for: Homeschool parents, Christian families, moms seeking natural health solutions, anyone dealing with chronic childhood illness, ADHD, autism, or fertility challenges.
Beat BLOAT & unlock better protein absorption and digestion with MassZymes by BiOptimizers. NOW GET 15% off your order with the code VANESSA at bioptimizers.com/vanessa In this solo episode, Vanessa Spina breaks down the science and strategy behind one of the most effective tools for rapid fat loss and muscle preservation — the Protein-Sparing Modified Fast (PSMF). Following her in-depth interview with Dr. David Jockers, Vanessa explains exactly how this approach works, why it's so powerful for resetting metabolism, and how to implement it safely for optimal results. If you've ever wondered how to burn fat quickly without losing muscle, how to overcome plateaus, or how to use short, strategic fasting phases for body recomposition, this episode is your ultimate guide. Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa
In this Huberman Lab Essentials episode, my guest is Dr. David Sinclair, PhD, a professor of genetics at Harvard Medical School and a leading expert on the biology of aging. We discuss the cellular and molecular mechanisms of aging—and how specific behaviors, such as fasting, regular exercise and NAD⁺-boosting compounds like NMN, can activate the body's natural longevity pathways. This discussion highlights how lifestyle choices profoundly influence the aging process and may even slow or reverse key aspects of biological aging. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AGZ by AG1: https://drinkagz.com/huberman David: https://davidprotein.com/huberman Eight Sleep: https://eightsleep.com/huberman Timestamps (0:00) David Sinclair (0:20) Longevity, Anti-Aging, Aging as a Disease (2:27) Causes of Aging; Epigenome & Genes (4:53) CD & Scratches Analogy, DNA, Silencing & Expressing Genes (6:44) Physical Appearance & Aging (7:36) Sponsor: David (8:54) Childhood Development & Aging, Horvath Clock, Accelerate Aging (11:30) Rates of Puberty & Aging, Growth Hormone (12:37) Body Size & Longevity; Epigenetics (13:07) Fasting, Calorie Restriction & Longevity, Sirtuins, Insulin & Glucose (16:31) Tool: Skip a Meal (17:07) Longer Fasts & Autophagy, “Deep Cleanse” (18:07) Sponsor: AGZ by AG1 (19:36) Fasting, Fluids, Electrolytes (20:16) Sirtuins, Glucose, mTOR & Fasting; Leucine, Tool: Pulsing Behaviors (24:24) Breaking a Fast, Tools: Do Your Best; Transitions (27:00) Sirtuins, NAD, NMN Supplementation (29:04) Sponsor: Eight Sleep (31:10) Iron & Senescent Cells; Personalize Medicine (32:40) Tool: Blood Markers, CRP (34:50) Tool: Aerobic & Resistance Exercise (35:55) Estrogen, Fasting & Fertility; Aging & Rejuvenation (38:20) Acknowledgements Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices
In this solosode of The Energy Code, Dr. Mike unveils the most comprehensive update yet to BioLight's flagship supplement — BioBlue — and takes listeners deep inside the quantum bioenergetic thinking that shaped its redesign. What began as a methylene-blue-based mitochondrial catalyst has evolved into a next-generation longevity systemintegrating deuterium-depleted water, elevated NMN, taurine, and trace gold-silver resonance compounds. Dr. Mike breaks down the science and reasoning behind each refinement: why Litewater's 10 ppm deuterium-depleted water now forms the clean matrix for all BioBlue liquids, how NMN has been increased ten-fold (10 mg → 100 mg) to meaningfully expand NAD⁺ pools and drive biogenesis, and how taurine stabilizes mitochondrial membranes and calcium signaling for endurance and resilience. He explains the subtle yet powerful tweaks — like a 50 % increase in colloidal gold and silver and a 40 % reduction in fulvic acid — that sharpen redox coherence and enhance longevity signaling. Dr. Mike dives into: Overview of how BioBlue progressed from a simple methylene-blue solution to a full mitochondrial optimization system. Why all BioBlue liquids now utilizes Litewater for cleaner proton flow and improved ATP efficiency. Why NMN increased from 10 mg → 100 mg per dose to meaningfully raise NAD⁺ levels, drive biogenesis, and enhance DNA repair. Why the addition of Taurine – 100 mg per serving for membrane stability, calcium regulation, and long-term mitochondrial resilience. Enhanced Trace Elements – 50 % more colloidal gold & silver plus refined fulvic acid for smoother redox flow and higher photodynamic efficiency. This episode isn't just about formulation — it's about why every molecule matters in the pursuit of mitochondrial efficiency, redox stability, and long-term cellular youthfulness. Mike also previews BioLight's upcoming new website, pre-Black-Friday event, and a soon-to-launch BioBlue Lite product line for those seeking simplicity without compromise. Key Topics Covered Evolution of BioBlue — from the original methylene blue + NMN formula to a comprehensive mitochondrial optimization system. Integration of Deuterium-Depleted Water (Litewater, 10 ppm) — explanation of how lowering deuterium enhances ATP production, redox efficiency, and longevity potential. NMN Upgrade (10× Increase) — new 100 mg per serving dosage for boosting NAD⁺ levels, mitochondrial biogenesis, DNA repair, and energy metabolism. Addition of Taurine (100 mg per serving) — supports membrane integrity, calcium balance, ROS buffering, and cellular longevity signaling. Enhanced Colloidal Gold & Silver (50 % Increase) — improved redox stability, electron flow, and photodynamic synergy with methylene blue and red light. Refined Wu Jin Sun Fulvic Acid (−40 %) — optimizes redox balance and mineral transport while improving synergy between all active compounds. Comprehensive Mitochondrial Benefits — improved ATP efficiency, autophagy, and mitochondrial biogenesis for cleaner, more resilient energy production. New Product Lineup — introduction of BioBlue Lite and BioBlue Leuco Lite (simplified methylene blue + water versions) for accessible mitochondrial support. Key Quotes from Dr. Mike “Deuterium-depleted water doesn't just make the mitochondria go faster—it helps them run truer, cleaner, and more efficiently.” “We've moved BioBlue from a trace metabolic nudge to a real mitochondrial optimization protocol that supports redox cycling, biogenesis, and longevity pathways in a quantifiable way.” “Taurine turns BioBlue from a fast-acting energy compound into a cellular longevity stack—supporting repair, recycling, and resilience.” “By increasing colloidal gold and silver within their optimal bio-signal zones, BioBlue transforms from a chemical redox supplement into a biophysical energy transducer.” “Each change — from Litewater to taurine — was made to help your mitochondria run longer, cleaner, and more accurately. This is longevity through bioenergetics.” Episode Timeline 00:00 – Announcements: Pre-Black Friday + new website 04:00 – The origin of BioBlue and its evolution 10:00 – Introducing the upgraded BioBlue formula 11:00 – Why BioLight partnered with Light Water 12:00 – How deuterium slows mitochondrial ATP production 17:00 – Functional benefits of deuterium-depleted water 19:00 – 10x increase in NMN for energy and repair 27:00 – Synergy between NMN and methylene blue 30:00 – Adding taurine for stability and longevity 39:00 – Increasing colloidal gold for photonic synergy 46:00 – Boosting colloidal silver for redox protection 52:00 – Why lowering fulvic acid improves coherence 56:00 – What's next: BioBlue Light + legacy pricing offer 01:02:00 – Dr. Mike's closing thoughts on mitochondrial optimization Resources & References Deuterium Depletion and Mitochondrial Efficiency Boros, L. G. Deuterium Depletion and Cellular Bioenergetics. Frontiers in Oncology (2020). Sagalevsky, V. — Light Water: The Science of Deuterium-Depleted Hydration (interview referenced in episode). Nicotinamide Mononucleotide (NMN) & NAD⁺ Metabolism Mills, K. F. et al. Long-term administration of NMN mitigates age-associated physiological decline in mice. Cell Metabolism (2016). Yoshino, J. et al. NAD⁺ intermediates: The biology and therapeutic potential of NMN and NR. Cell Metabolism (2018). Taurine and Longevity Pathways Wang, W. et al. Taurine deficiency as a driver of aging. Science (2023). Schaffer, S. W. et al. Physiological roles of taurine in the heart and mitochondria. Journal of Biomedical Science (2010). Colloidal Gold & Silver in Cellular Redox Systems Li, Y. et al. Gold nanoclusters enhance mitochondrial cytochrome c oxidase activity. ACS Nano (2019). Kim, Y. S. et al. Silver nanoparticles exhibit SOD- and catalase-like activity for redox modulation. Nano Research (2020). Fulvic & Humic Acids as Bioactive Redox Modulators Senesi, N. Nature of humic substances and their interactions with trace metals and organics in the environment. Soil Science (1992). Wu Jin San extract — traditional Chinese “gold medicine” formulation known for enhanced mineral transport and detoxification support. Additional Mentions PGC-1α, SIRT1/SIRT3, and Autophagy pathways in mitochondrial biogenesis and longevity. Quantum redox coupling and plasmonic resonance as mechanisms for light-driven bioenergetic optimization.
Most people try to “heal” their brain with supplements, mindset, or meditation—but this episode reveals the deeper protocol to actually grow a new brain, reverse stress damage, activate 1,100 healing genes, and unlock higher human performance at any age. You'll learn how neuroplasticity, mitochondria repair, plant-based NRF2 activators, and energetic practices work together to rebuild the brain and extend longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Alberto Villoldo, Ph.D.—medical anthropologist, neuroscientist, energy medicine pioneer, and founder of The Four Winds Society, the gold-standard school for modern shamans. He has spent 25+ years studying Amazonian and Andean healing traditions, led the Biological Self-Regulation Lab at San Francisco State University to explore psychosomatic medicine, and authored more than 25 bestselling books on neuroscience, functional medicine, and energy healing. Few people on earth bridge ancient biohacking and modern brain science at this level. He also reveals the forms of nicotine that are safest (spoiler: it's not vapes or cigarettes), how nicotine works at the receptor level, and what the science says about long-term health effects. This episode blends functional medicine, brain optimization, and biohacking into one powerful, myth-busting breakdown. You'll learn: • How to grow a new brain every 22 days using neuroplasticity and mitochondria support • Why plant medicines and NRF2 activators can turn on 1,100 healing genes in 24 hours • The surprising link between nootropics, psychedelics, serotonin, and endogenous DMT • How mindset, belief systems, and placebo/nocebo shape immune function and metabolism • Why RFK's chronic disease warning connects to viral evolution and immune collapse • The real reason carnivore diets work—and when they fail without gut repair • Peptides, GLP-1 agonists, and the future of functional medicine hacking • Why most people sabotage themselves and how to stop fighting your own biology This is essential listening for anyone serious about biohacking, human performance, and longevity, and for those who want to understand how functional biology and mitochondrial science are redefining recovery, energy, and aging. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: NRF2 activation, Neurogenesis and hippocampus repair, Plant-based epigenetic triggers, Psychosomatic health, Serotonin to DMT conversion, Pineal gland methylation, Parasites and brain inflammation, Viral-driven evolution, GLP-1 agonists and longevity, Psilocybin lifespan extension, Autophagy and brain cleanup, Energetic medicine training, Functional peptides, BPC-157, Breathwork and CO2 tolerance, mTOR cycling, Cold exposure and dopamine, Mindset-driven immune function Thank you to our sponsors! • EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off. • Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. • Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. • fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Resources: • Learn more from Alberto at: www.thefourwinds.com and www.albertovilloldo.net • Buy the book ‘Grow A New Brain': https://a.co/d/5lVhrVy • Business of Biohacking | Register to attend October 20-23 in Austin, TX https://businessofbiohacking.com/ • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:25 — Introduction & Ayahuasca Story 3:15 — Shamanism Beyond Plant Medicine 6:53 — Losing Your Mind to Evolve 10:45 — The 22-Day New Brain Cycle 12:53 — Plant Communication & Direct Knowing 15:35 — Parasites, Liver Failure & Brain Damage 20:25 — Remote Healing & CIA Research 22:40 — Tryptophan, Turkey Farmers & Brain Chemistry 25:19 — Viruses as Evolutionary Drivers 30:30 — Psilocybin & Life Extension 35:25 — Healing with Mindset + Biology 38:52 — Spirit, Purpose & Growing Gods 43:49 — Plants, Protein & mTOR 49:07 — Training the Four Brains 51:16 — Cold Exposure: Pain vs Suffering 54:40 — Who Am I? Living the Question 55:25 — Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this episode, Ben Azadi, best-selling author of Keto Flex, shares the results of his five-day water fast — no food, no coffee, no shakes, only water and minerals. What began as a personal experiment turned into a deep physical, mental, and spiritual transformation. Ben walks you through what happens inside the body at each stage of fasting — from autophagy and ketone productionto dopamine reset, stem cell regeneration, and immune system renewal. You'll learn how fasting can help you heal, boost focus, enhance energy, and even reset your relationship with food. He also explains exactly how to break a long fast safely, when women should fast based on their cycle, and how to prepare your body for success.
Beat BLOAT & unlock better protein absorption and digestion with MassZymes by BiOptimizers. NOW GET 15% off your order with the code VANESSA at bioptimizers.com/vanessa In today's solocast, we break down a brand new clinical trial that tested whether a high-protein diet really shuts down autophagy — and what it means for fat loss and body composition. For years, many believed that eating more protein would block the body's cellular clean-up process, and that only low-protein fasting diets could deliver longevity benefits. But does the science actually back that up? This new randomized controlled trial put high-protein and low-protein diets head-to-head, measuring weight loss, belly fat, metabolic health, and markers of autophagy. The results may surprise you — and they could change how we think about protein for fat loss and longevity. Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa We'll explore: Why autophagy matters for health and aging How the trial compared high vs. low protein under calorie restriction What the researchers found on belly fat, IGF-1, and cellular clean-up What this means for your fat loss and body recomposition goals IQBAR — Brain + body nutrition bars with high protein and clean ingredients. Get 20% off all products by texting VANESSA to 64000. Get my NEW high-protein keto guide: The Keto Reset eBook Learn more about the TONE LUX Crystal red light therapy mask and the accessory the TONE LUX CONTOUR for the neck and décolleté and get 20% OFF with the code VANESSA Free high-protein keto guide: The Keto Reset eBook