Podcasts about Autophagy

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As we near the end of the school year, I'd like to give a shoutout to Mr George Gaskin's 7th grade history class at Harvard-Westlake School who are fans of this program. Have you ever wondered what keeps your cells functioning properly? The answer might be a molecule with a funny name but serious implications for longevity. Spermidine, found in every living cell on Earth, is essential for triggering autophagy—your body's internal cleaning system that recycles damaged cellular components.Biochemist Dr. Melissa Cano takes us deep into the fascinating world of cellular metabolism, explaining how this small but mighty molecule could be key to healthier aging. Our spermidine levels naturally decline as we age, precisely when we need its protective effects most. This decline happens through three pathways: diminished internal production, changes in gut microbiome, and potentially decreased absorption from food—creating a perfect storm for cellular aging.What makes this conversation particularly compelling is the growing body of evidence supporting spermidine's role in longevity. Epidemiological studies show people with higher dietary spermidine intake live 5-10 years longer on average. In lab studies, supplementation extends lifespan in multiple organisms by 5-20%. A groundbreaking 2024 study in Nature Cell Biology even revealed that spermidine mediates many of fasting's benefits—suggesting this molecule could be a natural caloric restriction mimetic without the hunger.Whether you're already familiar with longevity compounds like rapamycin and metformin or just beginning your healthy aging journey, this episode offers practical insights for everyone.  Ready to support your body's natural cleaning and rejuvenation processes? Learn how this remarkable molecule works at the cellular level and discover if spermidine supplementation might be the missing piece in your longevity strategy.This episode is sponsored by SpermidineLife whose products are mentioned in the program.  Use promo code ROB15 for discount. https://spermidinelife.us/products/spermidinelife-extra-dietary-supplement?utm_source=Lufkin&utm_medium=podcastLies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (20% off 'LUFKIN20') https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin At home blood testing (15% off)https://pathlongevity.com/Mimio Health (15% off 'LUFKIN') https://mimiohealth.sjv.io/c/5810114/2745519/30611 Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmdInstagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/Facebook: https://www.facebook.com/robertlufkinmd Threads: https://www.threads.net/@robertlufkinmdBluesky: ...

In this episode, Dr. Jockers and Dr. William Hsu dive into how nourished fasting can reduce insulin resistance, activate autophagy, and slow aging. They discuss how the fasting mimicking diet triggers cellular repair while still providing nourishment.   Learn how nutrient-sensing pathways like mTOR and IGF-1 influence metabolic health and why modern eating habits may accelerate aging. Dr. Hsu explains how short-term fasting can promote healing by tapping into the body's natural survival mechanisms.   Discover how to apply nourished fasting in your life with the ProLon protocol and why a few cycles a year can significantly improve your healthspan.   In This Episode: 00:00 Introduction to the Fast Mimicking Diet 02:49 Interview with Dr. William Hsu: Metabolic Health and Fasting 04:48 The Science Behind Fasting and Cellular Healing 06:49 The Evolutionary Perspective on Fasting 09:22 Understanding Nutrient Sensing Pathways 14:33 The Nobel Prize-Winning Research on Autophagy 17:44 The Concept of Fasting Mimicking Diet 21:25 Exploring the Benefits of Fasting Mimicking Diet 22:01 The Science Behind Fasting and Systemic Health 23:22 The Role of Lifestyle Medicine 24:16 Understanding Digestive Health and Stomach Acid 26:10 Hormetic Stress and Health Benefits 27:16 Clinical Research on Fasting Mimicking Diet 31:32 Practical Application of Fasting Mimicking Diet 32:43 Personalized Programs for Health Conditions 35:22 The Future of Lifestyle Medicine 40:54 Final Thoughts and Call to Action     Still cooking with seed oils? That could be fueling inflammation. I've switched to Paleovalley's 100% grass-fed beef tallow—it's rich in CLA, packed with flavor, and stable at high heat. It's one of the cleanest, most nutrient-dense fats you can cook with. Head to paleovalley.com/jockers and use code JOCKERS for 15% off your order. Heartburn doesn't mean you have too much stomach acid—it usually means you don't have enough. That's why I recommend Just Thrive's Digestive Bitters. They help ignite stomach acid, enzymes, and bile so you can finally break down food the way you're supposed to. Go to justthrivehealth.com and use code JOCKERS to save 20%.       "Autophagy is your body's self-cleaning cycle—and most people never turn it on." ~ Dr. Jockers     Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean  TuneIn Radio     Resources: Get 15% off Paleovalley Beef Tallow: paleovalley.com/jockers – Use code JOCKERS Save 20% on Just Thrive Digestive Bitters: justthrivehealth.com – Use code JOCKERS       Connect with Dr. William Hsu:  Website: https://l-nutra.com/portfolio/william-hsu-md/ Prolon 5 Day Fasting Mimicking Diet: https://prolonlife.com/       Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/     If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/  

Can water fasting cure cancer? After two decades in Western oncology, Dr. Katie Deming, MD walked away from the system—because she saw what no one wanted to say out loud:

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this “Ask Me Anything” (AMA) episode, Peter revisits the topic of fasting, sharing how his thinking has evolved over time. The episode explores fasting-related terminology and common types of fasting, as well as the various reasons individuals might choose to fast. Peter explores potential benefits including improvements in body composition, metabolic health, lifespan extension, cardiovascular disease, cancer prevention and treatment, neurodegenerative conditions such as Alzheimer's and Parkinson's, and autoimmune symptoms like arthritis. He also examines the risks and potential downsides of fasting and offers a practical framework to help assess when and how fasting may be most appropriately applied. If you're not a subscriber and are listening on a podcast player, you'll only be able to hear a preview of the AMA. If you're a subscriber, you can now listen to this full episode on your private RSS feed or our website at the AMA #72 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here. We discuss: Why the topic of fasting is being revisited [1:45]; The importance of being open to changing one's opinion in science and medicine as new evidence emerges [4:15]; Defining fasting and how it fits in the framework of dietary restriction, time-restricted feeding, and calorie restriction [7:30]; The most common types of fasting [11:45]; Why someone might choose fasting over continuous caloric restriction [19:00]; The biochemical effects of fasting: fuel partitioning, autophagy, and more [21:00]; Autophagy: a cellular cleanup process stimulated by fasting and energy depletion [26:00]; Comparing the physiological effects of a ketogenic diet to those of long-term fasting [27:45]; How long fasting takes to induce ketosis and boost autophagy, and how autophagy is measured [29:45]; At-home tests for ketones [33:45]; Reducing senescent (“zombie”) cells and inflammation through autophagy [35:00]; Examining the evidence for the long-term health benefits of fasting beyond short-term metabolic effects [37:15]; The common health claims associated with fasting across metabolic, neurological, oncological, autoimmune, and longevity domains [40:30]; The impact of fasting on body weight and body composition [42:00]; Weight regain and potential metabolic consequences of fasting [44:00]; The risk of lean mass loss with fasting and how to mitigate it [47:15]; A practical framework for using fasting as a strategy to improve body composition [52:15]; How extended fasting compares to caloric restriction in improving insulin sensitivity in people with insulin resistance or type 2 diabetes [54:00]; Is there any evidence that fasting can extend lifespan? [55:45]; Examining whether fasting improves cardiovascular disease risk beyond the effects of weight loss and calorie reduction [58:15]; Exploring whether prolonged fasting can reduce cancer risk [59:45]; The potential benefits of fasting or fasting-mimicking diets during cancer treatment: emerging evidence and practical considerations [1:02:15]; Fasting for protection against neurodegenerative diseases: early evidence of therapeutic benefit and open questions [1:10:45]; Various fasting methods for autoimmune diseases: potential symptom relief with cautious application [1:14:00]; Fasting and type 1 diabetes: risks, evidence, and careful dietary alternatives [1:16:45]; Fasting and gut disorders: potential benefits outside of flare-ups [1:18:45]; The primary risks and downsides associated with fasting [1:19:45]; The essential vitamins and minerals to supplement during prolonged fasting [1:21:30]; Who should avoid fasting and why [1:22:15]; Fasting's role in health: where it shows promise and where it likely offers no distinct advantage over caloric restriction [1:23:45]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

Episode #208 In this Fasting Q&A episode, hosted by Coach Lisa Chance, Dr. Jason Fung answers questions from the TFM Community: Do you think healthy individuals should take a daily multivitamin? [04:40] I am a 300-pound male and usually have about 20g of protein a day when I fat fast. If I have more, I can't stick with it. I've found that before I do a 66 (two per week), I need about 140-200g of protein the day before in order to complete the fast. In other words, doing a fat fast right before my fast doesn't hold me and I binge. Is there anything wrong with doing this? [05:50] What is the best way to extend a fast when someone has a history of gout? [11:40] What is your opinion on Dr. Roy Taylor's work about the pancreas not really being burned out but clogged with fat so the beta cells cannot function properly? [12:51] If someone has a high LP(a) of over 200, but their Trigs:HDL ratio is 1:1, then don't worry, but what about plasmapheresis for Lp(a)? [14:19]  Will younger people respond quicker to IF than older people? [15:45] I've read the science behind creatine and the many benefits to your muscles (I weight train) and your brain, and recently purchased a high quality brand. Creatine doesn't contain protein, it's a naturally occurring compound made from amino acids arginine, glycine, and methionine, so will it prevent autophagy? [17:15] If instead of adding MCT oil to the morning coffee we would take an omega pill instead, which of these might have less of an insulin release? [19:49] TFM's Book Club is reading Dr. Christopher Palmer's “Brain Energy” this month. He covers the metabolic theory of mental health, specifically with regards to mitochondrial health and optimal brain-energy metabolism impacting our prefrontal cortex function. Can you talk about this ‘hidden in plain sight' mental metabolic disorder of the brain, showing the progressive degeneration of the prefrontal cortex seen so rampant in our culture today? [21:21] What kind of fasting protocol can be done for someone considered to be a TOFI and doesn't want to lose too much weight? [25:34] There's some conflicting research on how keto and fasting affects T3 levels. For individuals with low T3 production, do you recommend a specific keto or fasting approach and are there any important considerations? [27:26]   LINKS  Dr. Fung's Livestream on YouTube (April 30, 2025) https://www.youtube.com/live/bZCS-trzJWM?si=BzzR0EgHpwiSZU5A Dr. Fung's Medium article (free to access for TFM Community members) The (Lack of) Benefits of Supplements https://drjasonfung.medium.com/the-lack-of-benefits-of-supplements-65bc09eb9774 Low carbohydrate and psychoeducational programs show promise for the treatment of ultra-processed food addiction. Jen Unwin et al https://pubmed.ncbi.nlm.nih.gov/36245868/ Yale Food Addiction Scale https://sites.lsa.umich.edu/fastlab/yale-food-addiction-scale/   Sign up TODAY for the Optimize Your Weight (Fat) Loss Workshop with Heather Shuker, CRNP.  Starts July 15th. 10% Discount with code PODCAST10 https://www.thefastingmethod.com/masterclasses-and-live-workshops-2025/#Optimize   Please note that you need to be a member of the TFM Community to submit questions to the Q&A webinars with Dr. Fung but you can submit questions to our regular Q&A episodes here: https://bit.ly/TFMPodcastQs Transcripts of all episodes are available on the Podcast page at www.thefastingmethod.com Explore the TFM Community with a 7-Day FREE TRIAL https://www.thefastingmethod.com/community/   Book a complimentary 15-minute coaching intake assessment with one of the TFM coaches https://www.thefastingmethod.com/coaching/   Connect With Us Instagram: https://www.instagram.com/fastingmethod/ Facebook Page: https://www.facebook.com/TheFastingMethod Join our FREE Facebook Group: https://bit.ly/TFMNetwork   Summary Timestamps 00:00 Intro 04:40 Multivitamins 05:50 Too Much Protein? 11:40 Fasting with Gout 12:51 Fatty Pancreas 14:19 Lp(a) and Plasmapheresis 15:45 Age Response to IF 17:15 Creatine and Autophagy 19:49 MCT Oil/Omega 3 and Insulin Realease 21:21 Mitochondrial Health 25:34 Fasting for TOFIs 27:26 Keto and Fasting for Thyroid Health   Disclaimer This podcast is for educational purposes only and is not a substitute for professional care by a doctor or other qualified medical professional. You should always speak with your physician or other healthcare professional before doing any fasting, changing your diet, taking or adjusting any medication or supplements, or adopting any treatment for a health problem. The use of any other products or services purchased by you as a result of this podcast does not create a healthcare provider-patient relationship between you and any of the experts affiliated with this podcast. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.

Welcome to the The Confab, the term derives from "confidential talk", which was commonly used in the Prohibition Era for meetings and conversations that took place in the smoky, rule-breaking speakeasies of that time.The informal, privacy focused and clandestine nature of Ungovernable Misfits lends itself to these discussions. So, grab a seat and a stiff drink from the concealed bar, listen and revel in the conversation.In this episode, Max chats to K about performance enhancements. Covering diet, supplements and pharmaceutical interventions and how you can own the keys to your health and make a beast out of yourself.IMPORTANT LINKS https://freesamourai.comhttps://p2prights.org/donate.htmlhttps://ungovernablemisfits.comVALUE FOR VALUEThanks for listening you Ungovernable Misfits, we appreciate your continued support and hope you enjoy the shows.You can support this episode using your time, talent or treasure.TIME:- create fountain clips for the show- create a meetup- help boost the signal on social mediaTALENT:- create ungovernable misfit inspired art, animation or music- design or implement some software that can make the podcast better- use whatever talents you have to make a contribution to the show!TREASURE:- BOOST IT OR STREAM SATS on the Podcasting 2.0 apps @ https://podcastapps.com- DONATE via Paynym @ https://paynym.rs/+misfit- DONATE via Monero @ https://xmrchat.com/ugmf- BUY SOME STICKERS @ https://www.ungovernablemisfits.com/shop/FOUNDATIONhttps://foundation.xyz/ungovernableFoundation builds Bitcoin-centric tools that empower you to reclaim your digital sovereignty.As a sovereign computing company, Foundation is the antithesis of today's tech conglomerates. Returning to cypherpunk principles, they build open source technology that “can't be evil”.Thank you Foundation Devices for sponsoring the show!Use code: Ungovernable for $10 off of your purchaseCAKE WALLEThttps://cakewallet.comCake Wallet is an open-source, non-custodial wallet available on Android, iOS, macOS, and Linux.Features:- Built-in Exchange: Swap easily between Bitcoin and Monero.- User-Friendly: Simple interface for all users.Monero Users:- Batch Transactions: Send multiple payments at once.- Faster Syncing: Optimized syncing via specified restore heights- Proxy Support: Enhance privacy with proxy node options.Bitcoin Users:- Coin Control: Manage your transactions effectively.- Silent Payments: Static bitcoin addresses- Batch Transactions: Streamline your payment process.Thank you Cake Wallet for sponsoring the show!(00:00:00) INTRO(00:02:08) THANK YOU FOUNDATION(00:02:52) THANK YOU CAKE WALLET(00:03:55) BOOSTS(00:06:28) Welcome Back (00:13:38) Disclaimer(00:15:00) Diet Basics(00:26:00) Jib Jab(00:26:47) Inflammation(00:30:53) Fibre(00:35:23) Cancer(00:38:02) Autophagy(00:40:55) Vitamins & Minerals(00:46:07) Training(00:49:07) Growth Hormone(00:50:13) Dig Bick(00:52:50) Needles or Tablets(01:00:53) Test is Best(01:08:14) PCT & HCG(01:12:50) DIY or Big Pharma(01:19:08) The Benefits(01:19:44) Healing Potions(01:22:00) Final Thoughts

Dr. Mindy dives into autophagy, that amazing natural way our cells clean house. While fasting is a top way to kickstart it, this episode shares three delicious foods that can actually give autophagy a boost even when you're not fasting: pineapple (thanks to bromelain), turmeric (with its powerful curcumin), and green tea (packed with EGCG). These goodies can help with things like keeping your arteries clear, making your skin glow, and maybe even fighting off certain cancers. Embrace the magic of autophagy with 3 game-changing foods! To view full show notes, more information on our guests, resources mentioned in the episode, discount codes, transcripts, and more, visit https://drmindypelz.com/ep290   Check out our fasting membership at resetacademy.drmindypelz.com. Please note our medical disclaimer.

This video is about my updated longevity-focused exercise routine—refined and tested over 14 years. And now, the tests show it helped me to kept my muscles a decade than my real age. So it reduces aging, I 100% feel it, and now you can see it in the result.You don't need to copy what I do. Instead, take the ideas and shape them around your world—your priorities, your health, your time.P.S. By the way, inviting you to check out how to freeze time—for precise longevity

Welcome to an eye-opening conversation with autophagy practitioner, movement coach, and founder of Genesis Health, Lars Konge, where we dive deep into the science and strategy behind using cellular autophagy to help slow—or even halt—the progression of Parkinson's Disease.

In this episode, we dive into the powerful fasting strategies that trigger autophagy — your body's natural process of deep cellular healing and renewal. Dr. Jockers shares simple ways to boost this critical process for better health and longevity.   You'll learn how to improve metabolic flexibility, why meal timing matters, and how fasting combined with exercise can enhance cell repair. Whether new to fasting or experienced, these insights support your health journey.   If you want to reduce inflammation, protect your brain, and boost cellular energy, this episode is a must-listen. Discover practical steps to harness autophagy's healing power today.     In This Episode:    00:00 Introduction to Autophagy  02:31 Fasting Strategies for Autophagy and Cellular Healing 03:38 Understanding Autophagy and Its Importance 10:11 Improving Metabolic Flexibility 13:38 Advanced Strategies for Enhancing Autophagy 24:03 Conclusion and Final Thoughts     Are swollen legs or ankles slowing you down? Discover the power of Lymph System Support by Pure Health Research. Crafted with natural ingredients like dandelion extract, burdock root, and bromelain, this formula unclogs your lymphatic system, reducing swelling and supporting a healthy inflammatory response.   As a special offer, try Lymph System Support risk-free today and receive a complimentary bottle of curcumin extract. Visit GetLymphHelp.com/jockers to claim yours now. Say hello to renewed vitality and goodbye to discomfort!     Say goodbye to sleepless nights with Purity Health's Pure Dose Magnesium. Unlike conventional supplements, its liposomal delivery method ensures better absorption, helping you fall asleep faster and wake up feeling refreshed. Try it today and experience the difference—backed by a 180-day money-back guarantee. Visit purityhealth.com/drj for an exclusive deal!     “Autophagy is your body's self-recycling process, rejuvenating cells and fighting chronic disease.”  ~ Dr. Jockers     Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio     Resources: GetLymphHelp.com/jockers Visit https://puralityhealth.com/drj     Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/   

Analyzing Trump's plan to roll back soaring drug prices for Americans; Sports bras eliminate bounce but may take a toll on women's backs; RFK Jr. targets the chemicals in our food; Do Americans really eat more animal protein than any other of the world's nations? Causes and treatments for pulmonary hypertension.

Can you be 10 to 20 pounds overweight and still be considered healthy? Ben Azadi says yes—but it all depends on where that fat is located. I had such a powerful conversation with Ben, FDN-P—he's the Founder of Keto Kamp and someone who's helped thousands (maybe millions!) of people break free from what he calls “metabolic prison.” We talked about the kind of fat that really puts your health at risk, and why looking lean doesn't always mean you're healthy. This one really made me rethink how we define “healthy”—especially as we get older. Ben shared how he lost 80 pounds and completely turned his life around, and now he's teaching others how to do the same—without crash diets or gimmicks. His book, Metabolic Freedom, is packed with real strategies to help you feel better, think clearer, and age in a healthier way. We got into the nitty-gritty of insulin resistance (something so many women in midlife are dealing with), how to become a fat burner instead of a sugar burner, and why fasting is more than just skipping meals—it's about giving your body a chance to heal. And he makes it all so doable, even if you're just getting started. I also asked Ben about his own routine—he shared some simple habits that make a big difference, like hydration tips, gratitude journaling, and how building muscle can help keep your metabolism humming. Oh, and speaking of feeling good… there's a brand-new flavor of my fave superfood drink, Mighty Maca Mango—it's zesty, refreshing, and just in time for summer. I've been loving it in sparkling water or frozen as popsicles (total game-changer). You can grab it at dranna.com and give your body that extra support it deserves!   Key Timestamps: [00:00:00] Introduction. [00:02:50] Metabolic freedom journey. [00:05:57] Metabolic prison explained. [00:08:04] Insulin resistance in women. [00:12:06] Strategies to remove the waist gain. [00:14:08] Ketones benefits and the issues it addresses. [00:19:36] Muscle is magic post-menopause. [00:20:31] Keto, inflammation, and thyroid health. [00:25:47] Autophagy as the key to cellular health. [00:30:00] What a typical day looks like for Ben Azadi. [00:34:05] Gratitude's impact on health. [00:35:39] Where is your fat located?   Memorable Quotes: "Calories matter. Don't get me wrong. They're just not the most important thing. Hormones and inflammation are the most important thing." [00:12:32] – Ben Azadi "We need to flex out and have a flexible metabolism because that's another form of a metabolic prison is only burning fat and ketones and not sugar." [00:21:57] – Ben Azadi   Links Mentioned:  Mighty Maca Mango: https://drannacabeca.com/products/mighty-maca Metabolic Freedom Book: https://metabolicfreedombook.com/ Connect with Ben Azadi: Website: https://www.benazadi.com/ Instagram: https://www.instagram.com/thebenazadi/ Facebook: https://www.facebook.com/thebenazadi/ LinkedIn: https://www.linkedin.com/in/benazadi/ Connect with Dr. Anna Cabeca: Website: https://drannacabeca.com/pages/show Instagram: https://www.instagram.com/thegirlfrienddoctor/ YouTube: https://www.youtube.com/@thegirlfrienddoctor TikTok: https://www.tiktok.com/@drannacabeca   Produced by Evolved Podcasting: https:// www.evolvedpodcasting.com

What happens to your body during a 3-day fast? In this video, we'll cover the fasting health benefits of both intermittent fasting and extended fasting for 72 hours or longer. I'll also share some expert fasting tips for even more fasting benefits. 0:00 Introduction: Not eating for 3 days?1:02 Intermittent fasting benefits1:44 Extended fasting benefits3:12 Autophagy and fasting 4:22 72-hour fast benefits 4:49 Immune benefits of extended fasting5:36 Fasting tips 6:28 How to break a fastDid you know that insulin resistance is behind most chronic diseases, including many types of cancer? Frequent eating leads to insulin resistance, which blocks cells from getting fuel. Diets involving 5 to 6 small meals daily destroy the metabolism the most!An intermittent fasting plan involving 18 hours of fasting with a 6-hour eating window can provide tremendous health benefits, such as weight loss in the midsection, improved mood, and decreased inflammation. A 24 to 48-hour fast can significantly magnify the benefits of fasting. Extended fasting enables you to deplete the stored glycogen in your liver. You may also notice significant initial water weight loss. During a 1 to 2-day fast, most of your fuel will come from ketones. Your microbes will thrive, and growth hormone will increase, boosting muscle growth and burning fat.Ketones will feed the neurons in the brain, so you may notice improved cognitive function.Extended fasting allows you to get into a state of autophagy, where your body removes damaged cells and proteins and creates new ones. Autophagy also allows you to build new brain cells. A 3-day fast can produce even more benefits! Extended fasting for 72 hours can clean up intracellular pathogens, including Epstein-Barr and herpes viruses. A 3-day fast can stimulate your immune system, protecting you against cancer and autoimmune diseases. You can achieve results similar to stem cell therapy for free!If you're unsure of how to fast and want to make the process as comfortable and beneficial as possible, try these fasting tips for the most fasting benefits:•Coffee and tea are okay during a water fast•Make sure you have enough sea salt•Consume electrolytes like potassium and magnesiumRefeeding can have a negative impact after a 3-day fast. It's best to rebuild your caloric intake slowly. Bone broth is a great option to break your fast. Dr. Eric Berg DC Bio:Dr. Berg, age 60, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the author of the best-selling book The Healthy Keto Plan, and is the Director of Dr. Berg Nutritionals. He no longer practices, but focuses on health education through social media.

In this episode, Dr. Jockers and Ben Azadi discuss metabolic freedom and its impact on longevity and inflammation. You'll learn why staying in sugar-burning mode harms your health and how fat-burning mode promotes healing.   Ben shares his journey from obesity to metabolic health and explains why metabolic flexibility is key to disease prevention. He highlights how fasting resets your metabolism and activates autophagy for cellular repair.   Discover how insulin affects fat burning and why lowering its levels boosts energy. Ben also covers how the right foods support metabolic health and the importance of reducing constant snacking.   In This Episode: 00:00 The Shocking Truth About French Fries and Cigarettes 03:08 Metabolic Freedom: Key to Longevity 05:18 Understanding Metabolic Health 06:35 The State of Metabolic Health in America 11:01 The Importance of Insulin in Metabolic Health 17:56 Calories vs. Hormones: The Real Debate 20:46 Feast and Famine: Ancestral Eating Patterns 26:06 The Dangers of Seed Oils 29:40 Healthy Fats vs. Seed Oils 30:07 The Hidden Dangers of Canola Oil 30:27 Avoiding Seed Oils When Dining Out 30:50 The Impact of Seed Oils on Your Body 31:09 Understanding Stomach Acid and Digestion 32:19 The Benefits of Digestive Bitters 32:58 Autophagy: The Body's Cleanup Process 33:33 The Role of Phosphatidylcholine 33:55 Autophagy and Fasting 34:03 The Refrigerator Analogy for Autophagy 35:17 The Process of Apoptosis 35:29 Fasting and Exercise 36:31 The Importance of Metabolic Flexibility 37:53 Preparing for Fasting 41:15 The Concept of Hormesis 43:34 Balancing Cortisol and Growth Hormone 48:02 Daily Routines for Optimal Health 52:56 The Wolverine Stack for Recovery     Looking for a delicious snack that's good for you? Paleovalley Superfood Bars are packed with organic, whole food ingredients like collagen protein, kale, and blueberries—providing all the nutrients your body needs. With flavors like Lemon Meringue and Red Velvet, you can enjoy a treat that supports gut health, joint function, and even wrinkle-free skin. Visit Paleovalley.com and use the code JOCKERS to save 15% on your order today. Snack smarter with Paleovalley Superfood Bars! Struggling with digestion? Just Thrive Digestive Bitters help stimulate the production of stomach acid, bile, and pancreatic enzymes, improving digestion, easing bloating, and enhancing nutrient absorption. It's the natural way to support your gut health and feel better after every meal. Visit justthrivehealth.com and use code JOCKERS to save 20% off your order!     "Metabolic freedom is about being able to burn fat when you need to and burn sugar when you need to." ~ Dr. Jockers     Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean  TuneIn Radio     Resources: Paleovalley - visit paleovalley.com/jockers Visit justthrivehealth.com and use code Jockers for a 20% discount     Connect with Ben Azadi: Website: https://www.benazadi.com/ Book: https://amzn.to/41O02jk     Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/   If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/  

Episode #204 In this Fasting Q&A episode, Megan Ramos answers some of your fasting questions: 1. On eating days I almost always feel very full. I try to make my meal portions smaller but I still feel full. I don't seem to feel hunger cues on eating days nor fasting days. Have 20 years of dieting broken my body? My usual fasting protocol is three 36s, lately, two 42s. (Ewelina) [01:34] 2. I've read on some of the PCOS blogs that you shouldn't skip breakfast because it balances your blood sugar, but I find it harder to meet my fasting goals when I eat breakfast. Is this a reference to early, time-restricted eating? Is it better to meet the fasting goal of longer fasts or to consume the meals earlier in the day? [04:45] 3. How do I not lose much more weight with extended fasts for autophagy? I am 71 and have lost 44  pounds over an 8-month period (1 pound on most weeks, never more). I have loose skin on my arms, belly, and legs, and I am looking older than I ever have! I will be doing 24-hour fasts to maintain my weight loss. (Anne) [09:47]  4. I started doing the 42-hour extended fasts (sometimes three a week, sometimes two) to switch it up. I'm not losing weight or inches. What am I doing wrong? (Sylvia from California) [13:10]    Please Submit Your Questions here: https://bit.ly/TFMPodcastQs Transcripts of all episodes are available on the Podcast page at www.thefastingmethod.com   Explore the TFM Community with a 7-Day FREE TRIAL https://www.thefastingmethod.com/community/ Book a complimentary 15-minute coaching intake assessment with one of the TFM coaches https://www.thefastingmethod.com/coaching/   Connect With Us Instagram: https://www.instagram.com/fastingmethod/ Facebook Page: https://www.facebook.com/TheFastingMethod Join our FREE Facebook Group: https://bit.ly/TFMNetwork   Summary Timestamps 00:00 Intro 01:34 Lack of hunger on eating days 04:45 Is breakfast necessary with PCOS? 09:47 Fasting for autophagy and loose skin reduction 13:10 Doing EF but still not losing weight or inches   Disclaimer This podcast is for educational purposes only and is not a substitute for professional care by a doctor or other qualified medical professional. You should always speak with your physician or other healthcare professional before doing any fasting, changing your diet, taking or adjusting  any medication or supplements, or adopting any treatment for a health problem. The use of any other products or services purchased by you as a result of this podcast does not create a healthcare provider-patient relationship between you and any of the experts affiliated with this podcast. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.

In this episode, Dr. Jockers explains how autophagy naturally tightens saggy skin by breaking down damaged cells and regenerating healthy ones. This process helps improve skin elasticity without surgery.   You'll discover why amino acids from protein are crucial for collagen and elastin production, and how good fats reduce oxidative stress that harms your skin.   Dr. Jockers shares how strength training and intermittent fasting boost growth hormone, enhancing skin health. Learn how vascular health and autophagy play a key role in skin rejuvenation.     In This Episode:   00:00 Introduction to Autophagy and Mitophagy 02:45 How to Get Rid of Loose, Saggy Skin 04:19 Understanding Skin Health and Autophagy 07:21 Nutritional Strategies for Healthy Skin 11:12 Exercise and Hormetic Stressors for Skin Health 16:15 The Role of Sleep and Sunlight in Skin Health 24:05 Conclusion and Final Thoughts     Explore the health benefits of C60, a Nobel Prize-winning antioxidant that optimizes mitochondrial function and fights inflammation. Visit shopc60.com and discover how to boost your immune system, detox your body, and increase energy. Use promo code 'Jockers' for 15% off your first order. Start your journey to better health with C60 today!   Unlock the full potential of your digestion with MassZymes by BiOptimizers, the most potent digestive enzyme on the market. With up to 500% more protease than other leading brands, MassZymes helps break down protein efficiently, preventing gut issues and improving nutrient absorption. Whether you're over 35 and facing natural enzyme decline or just want to enhance your digestive health, MassZymes offers a comprehensive solution. Try it risk-free today with BiOptimizers' 365-day money-back guarantee and experience the difference. Visit bioptimizers.com/Jockers and use code 'Jockers' to save 10% on your first order!       “Activate autophagy to naturally tighten saggy skin—your body is designed to heal itself!”    - Dr. Jockers     Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean  TuneIn Radio       Resources: Visit https://shopc60.com/jockers – Use code “JOCKERS” to get 15% off! Visit biOptimizers.com/Jockers       Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/   If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/  

Is hair analysis reliable for nutritional assessment? How to prevent recurrence of nasal polyps after sinus surgery; Diet matters after diagnosis of ovarian cancer; Health benefits of grass-fed butter; Does magnesium really improve sleep quality? Vitamin E for tardive dyskinesia; Continuous glucose monitors may exaggerate blood sugars.

What if your skincare routine could actually trigger your body's built-in anti-aging pathways? Most products just treat the surface, but aging starts much deeper, at the cellular level.In this episode of the Biohacking Beauty Podcast, I'm talking with Melissa Cano, Director of Education at Longevity Labs and one of the smartest voices out there when it comes to spermidine, autophagy, and cellular health. Melissa has spent years teaching practitioners and biohackers how polyamines like spermidine can activate the body's natural cleanup process, support mitochondrial health, and actually help cells function younger.We get into why autophagy is the key to skin renewal, why spermidine levels drop as we age, and how to use it (internally and topically) for real results. We also dig into what the latest research says about spermidine for gut health, sleep, hair—and why I believe it's one of the most important molecules in longevity science today.Melissa Cano is the Director of Education at Longevity Labs. Melissa is recognized for her work helping biohackers, clinicians, and health enthusiasts understand how molecules like spermidine support autophagy, mitochondrial function, and healthy aging.We Also Discuss:(00:01) Why spermidine might be the most important longevity molecule(05:13) Autophagy: the real anti-aging mechanism(14:38) Why fasting isn't enough without spermidine(25:10) How spermidine boosts collagen and skin renewal(31:20) The skin microbiome + topical spermidine connection(55:48) How long until you see results?Learn more about:Young GooseUse code PODCAST10 to get 10% off your first purchase, and if you're a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/ Instagram: @young_goose_skincareMelissa CanoWebsite: https://spermidinelife.us/ Instagram: @spermidinelife.us

Episode #202 In this Fasting Q&A episode, hosted by Coach Lisa Chance, Dr. Jason Fung answers questions from the TFM Community: I'm curious if TFM intends or would consider a ‘fasting-mimicking protocol' to be published for its members, possibly a TFM Quick Guide? [01:22] When I fast I find that I have trouble falling and staying asleep. Is it the hunger increasing my cortisol or the effect of ketones? What are your thoughts on valerian or kava tea to help with fasting insomnia? [02:54] What's the latest research on autophagy? [05:12]  What does research say about the relationship between the HDL/Triglycerides ratio and high coronary calcium scores? And, in general, what does the scientific literature say about potential interactions between statins and fasting regimens? [07:00]  There is a hormonal cascade where our sex hormones are made from cholesterol. We know from member stories that female hormones become balanced on alternate day fasting regimen. In those success cases, how does alternate-day fasting affect the hormonal cascade so that it starts working properly again? [12:59] I was recently reading research that suggests that moderate weight gain during menopause, particularly in lean women, may offer a degree of protection against cardiovascular disease, due to the increased production of adipose-tissue-derived estrogen, which can partially compensate for the decline in ovarian estrogen levels following menopause. What are your thoughts on this? [15:27] Why might weight loss stall during a multi-day fast, even when following an extended-fasting protocol with proper hydration, electrolytes, and exercise? What factors could influence the rate of weight loss, and how can one determine if adjustments are needed? [19:02] Is there a problem with lowering metabolic rate during fasting? Do I need to worry about this? [21:13] The RR interval typically refers to the time between consecutive R waves in an electrocardiogram (ECG/EKG) and is a fundamental measurement in heart rate variability (HRV). Has the RR interval been studied in diagnosing gastroparesis, specifically for diabetes? [24:51]   LINKS Cholesterol Ratio Calculator https://www.omnicalculator.com/health/cholesterol-ratio Longevity Summit video with Cynthia Thurlow on Dr. Fung's YouTube channel. A Conversation with Cynthia Thurlow | Jason Fung https://youtu.be/YeELPeaQEFg?si=88JJWDzyzjDPGK76   Please note that you need to be a member of the TFM Community to submit questions to the Q&A webinars with Dr. Fung but you can submit questions to our regular Q&A episodes here: https://bit.ly/TFMPodcastQs   LAST CHANCE to Sign Up for the Self-Sabotage Workshop with Dr. Terri Lance https://www.thefastingmethod.com/masterclasses-and-live-workshops-2025/#Self2 Discount Code - PODCAST10   Transcripts of all episodes are available at www.thefastingmethod.com on the Podcast page.   CONNECT WITH US Instagram https://www.instagram.com/fastingmethod/ Facebook Page https://www.facebook.com/TheFastingMethod Join our FREE Facebook Group  https://bit.ly/TFMNetwork   00:00 Intro 01:22 Fasting-Mimicking Diet Quick Guide? 02:54 Fasting and Insomnia 05:12 Latest Research on Autophagy 07:00 HDL/Trigs Ratio and high CAC Score 11:40 ADF and Balancing Female Sex Hormones 14:09 Weight Gain Protective in Perimenopause? 17:44 Weight-Loss Stalls During Multi-Day Fasts 19:55 Low/High Metabolic Rate 23:33 Heart rate Variability   Disclaimer This podcast is for educational purposes only and is not a substitute for professional care by a doctor or other qualified medical professional. You should always speak with your physician or other healthcare professional before doing any fasting, changing your diet, taking or adjusting  any medication or supplements, or adopting any treatment for a health problem. The use of any other products or services purchased by you as a result of this podcast does not create a healthcare provider-patient relationship between you and any of the experts affiliated with this podcast. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.

In this episode of Hart2Heart, Dr. Mike Hart breaks down his comprehensive supplement stack, divided into morning, afternoon, pre-workout, and nighttime routines. From neuroprotective agents like saffron and acetyl-L-carnitine to mitochondrial powerhouses like PQQ and CoQ10, each choice is supported by clinical studies and biochemical rationale. Dr. Hart also breaks down how to enhance brain function, support cardiovascular health, improve sleep, and optimize hormonal balance.  Show Notes: (0:00) Welcome back to the Hart2Heart Podcast with Dr. Mike Hart    (0:15) Dr. Hart does a solo covering his supplement stacks (1:00) Morning stack - saffron, alcar, cognitive health (5:00) Major benefits to  nattokinase (8:00) Vitamin k2 benefits (10:30) Fat soluble vitamins - vitamins A,D,E,K (11:40) Autophagy and anti-aging - spermidine and supplement timing (13:00) Beta-Alanine - performance and dosing strategy (14:00) Afternoon stack - zinc, boron, and testosterone balance (21:00) Vitamin D & synergistic support (22:30) Pre-workout stack - creatine, citrulline, beta-alanine, and HMB (26:00) Nighttime stack - sleep optimization with magnesium and apigenin (30:00) Fish oil: heart, brain, and REM sleep benefits --- Dr. Mike Hart is a Cannabis Physician and Lifestyle Strategist. In April 2014, Dr. Hart became the first physician in London, Ontario to open a cannabis clinic. While Dr. Hart continues to treat patients at his clinic, his primary focus has shifted to correcting the medical cannabis educational gap that exists in the medical community.  Connect on social with Dr. Mike Hart: Social Links: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart

Send us a textIn this episode of The StrongHer Way, Alisha Carlson sits down with Renee Fitton to unpack one of the most talked-about wellness tools today: fasting. But this isn't your average intermittent fasting chat. Together, they dive into the real science behind fasting, the differences in how men and women respond, and what every woman should know—especially during perimenopause and postmenopause.You'll hear about intermittent fasting, prolonged fasting, and fasting mimicking diets, as well as why women need a tailored approach based on their hormones, cycle, and recovery needs. Whether you're fasting for longevity, metabolic health, or to improve your relationship with food, this episode gives you both the research-backed benefits and the real-life risks.What You'll Learn in This Episode: The difference between intermittent, prolonged, and mimicking fasts  Why fasting hits differently for women—especially in perimenopause & postmenopause  How autophagy (your body's cellular cleanup crew) is triggered by longer fasts  When to fast and when to rest based on your menstrual cycle  Why weight loss should not be the main goal of fasting The role of caffeine and stress in fasting  Practical tips to safely incorporate fasting without wrecking your hormonesQuick Takeaways:  Match fasting protocols to your cycle  Consider fasting mimicking diets to reduce stress on the body  Focus on long-term metabolic health, not short-term fat loss  Use fasting as a tool for longevity and cellular repair  Always personalize your approach—your hormones, your rulesAbout our guest:RENEE FITTON, MS, RD is a leader in the intersection of nutrition, healthcare, and education. As Director of Education & Healthcare Sales at Prolon, she shapes sales strategies and equips healthcare practitioners with cutting-edge insights into nutrition and longevity. Her expertise in evidence-based practices and nutritional science has made her a trusted authority. Renee is dedicated to advancing the role of nutrition in revolutionizing healthcare, blending scientific rigor with a compassionate approach to wellness.MORE ONLINE:ProlonLife.comRenee's InstagramRenee's LinkedIn

Natalie Earle is a Functional Nutritional Therapy Practitioner with a Bachelor's degree in Physics. In 2013, she was diagnosed with prediabetes, skin issues, and severe PMS symptoms. By 2015, Natalie began following the GAPS diet, and over the subsequent years, she successfully reversed her prediabetes and brought her other symptoms into remission. For the past six years, she has worked with hundreds of clients, supporting individuals with autoimmune disorders, cancer, PCOS, endometriosis, and nervous system disorders. Sign up for our FREE newsletter: https://go.nutritionwithconfidence.com/nwc-newsletter-sign-up SUBSCRIBE: https://www.youtube.com/@HealingwithConfidencePodcast?sub_confirmation=1 Website: https://nutritionwithconfidence.com Follow Natalie on TWITTER (X): https://x.com/natalie_earle?mx=2 Follow Natalie on INSTAGRAM: https://www.instagram.com/nutritionwithconfidence/?hl=en ******* Dr. Sarah Myhill's Interview - https://www.youtube.com/watch?v=hxMQIiGieY4&t=5123s  Dr. Neil Nathan's Interview - https://www.youtube.com/watch?v=-Ut6nw3zspE    

Some Key Literature Review Studies from Year 14 This is a bit of a long newsletter. That is intentional. This will be a repository for some of the best research for us to look back on from time to time this coming year to solidify the learning moving forward. 1) Time restricted eating patterns are known to help physiology and metabolism by initiating a pause in the action of mTOR and muscle synthesis as well as inducing autophagy. Autophagy is critical to the clearance of broken or damaged cells following injury or disease.....Plus a to do list and recipe of the week. Dr. M

In this high-impact episode, we dive deep into the science and strategy behind autophagy, the body's built-in cellular clean-up system that promotes fat burning, energy, and longevity. You'll learn the best fasting protocols to turn on autophagy, how to measure it using blood glucose and ketones, what breaks a fast, and bonus biohacks to enhance autophagy without extended fasting. Free access to the Metabolic Freedom Course + interviews with Dr. Jason Fung, Dr. Daniel Pompa, Cynthia Thurlow & Megan Ramos when you order the book at http://www.metabolicfreedombook.com 

Dr. Hoffman continues his conversation with Dr. Sharon Bergquist, author of "The Stress Paradox: Why You Need Stress to Live Longer, Healthier, and Happier." 

Dr. Sharon Bergquist is an award-winning physician, innovative healthcare leader, and visionary researcher, renowned for spearheading a science-based approach to applying lifestyle as medicine. She is the author of "The Stress Paradox: Why You Need Stress to Live Longer, Healthier, and Happier." She discusses the misunderstood role of stress, emphasizing its potential benefits when managed and utilized correctly. Dr. Bergquist explains how stress can enhance cellular function, boost resilience, and improve overall health. She delves into topics such as the physiology of stress, the science of hormesis, and the benefits of controlled stressors including plant toxins, thermal exposure, fasting, exercise, and psychological challenges. The discussion underscores the importance of balancing stress and recovery to promote cellular repair and long-term well-being.

AUTOPHAGY--- Stop denying your body it's healing process- Heal and GROW- so you can thrive

This episode is brought to you by Caldera Lab, Fatty 15 and LMNT. Today we explore the fascinating world of fasting with Renee Fitton, MS, RD, a distinguished longevity dietitian. Renee takes us through the science of fasting, emphasizing that you can fast with food, and discusses its surprising benefits for sexual health and even optimizing testosterone levels. She shares her expertise in longevity nutrition, highlighting how understanding biochemical pathways and innovations in healthcare can extend our health span. Listen in as we address common myths about fasting and introduce the fasting-mimicking diet, showcasing how fasting can regulate blood sugar and improve metabolism, while also enhancing brain health, particularly in the context of Alzheimer's. Follow Renee @fittonnutrition Follow Chase @chase_chewning ----- In this episode we discuss... (00:00) Benefits of Fasting for Health (06:46) Types of Fasting for Optimal Longevity (18:17) Fasting Myths and Truths (24:30) Caffeine, Plant Compounds, and Fasting (28:55) Reversing Type 2 Diabetes (40:56) Fasting Types and Safety Protocols (47:10) Prolonged Fasting Differences  (01:13:39) Biological Age, mTOR, and Transitioning Out of a Fast (01:24:54) Fasting Mimicking Diet Protocol (01:38:21) Embracing Progress, Not Perfection ----- Episode resources: Get 20% off your first order of premium men's skincare products with code EVERFORWARD at https://www.CalderaLab.com  Get an additional 15% off the C15:0 90-day starter kit with code EVERFORWARD at https://www.Fatty15.com/everforward Get a FREE sample variety pack of the best-tasting electrolytes with zero sugar at https://www.DrinkLMNT.com/everforward  Watch and subscribe on YouTube Fasting and religious purposes Fasting-mimicking and longevity

Are you ready to uncover the secret to reversing biological age and boosting your midlife vitality? In this episode, Leslie Kenny takes us into the fascinating world of spermidine, a molecule that holds the key to managing menopause symptoms and enhancing overall health. How can this hidden molecule transform your sleep, skin, and hair health? Join us as we unravel the mysteries of menopause and explore the power of spermidine in maintaining youthful energy and balance. Can it truly reverse hair loss and improve sleep quality? Discover the unexpected ways this molecule supports cellular renewal and hormone regulation. What role does bioidentical hormone replacement therapy play alongside spermidine in promoting health and longevity? How can these strategies help you navigate the challenges of aging with grace and resilience? Get ready for a captivating journey into women's health biohacking! In this episode, we uncover: How Leslie defied medical odds and maintained a youthful biological age. Why spermidine is crucial for managing menopause symptoms and boosting cellular health. What unexpected benefits spermidine offers for hair growth, sleep, and hormone balance. How bioidentical hormone replacement therapy complements spermidine for menopausal support. Why sourcing spermidine from food-derived supplements is essential for safety and efficacy. Don't miss this episode filled with insights that could transform your health journey. Tune in to learn how you can harness the power of spermidine for a vibrant, ageless life!   Sponsors Get 15% off your Primadine purchase with coupon code KM15 here. Get 40% off your Cozy Earth bedding, pyjamas and more with coupon code HORMONES at cozyearth.com   Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada.   Visit karenmartel.com to explore our comprehensive programs: Bioidentical Hormone Replacement Therapy Individualized Weight Loss Programs  Peptide Therapy for weight loss    Interested in our NEW Peptide Weight Loss Program? Join today and get all the details here.   Join our Women's Peri and Post Menopause Group Coaching Program, OnTrack, TODAY!   To our nursing audience members, our podcasts qualify for nursing CE @ RNegade.pro. Provide # CEP17654.   Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert   Karen's Facebook Karen's Instagram

Biohacking for Longevity: Extending Your Health Span. In this episode of "Leyla Weighs In," registered dietician and nutritionist Leyla Muedin discusses the concept of biohacking and its potential to extend lifespan and health span. Leyla explores various biohacking strategies such as diet optimization, regular physical activity, stress management, enhancing sleep quality, and maintaining strong social connections. She emphasizes the importance of epigenetics, targeted lifestyle changes, and advanced medical interventions like stem cell therapy. You will learn practical biohacking tips, including the benefits of intermittent fasting, the significance of exercise, and how to use wearable technology for health tracking. Leyla also highlights the role of supplements and personalized nutrition in promoting longevity, alongside maintaining good dental health and a sense of purpose. Through these combined efforts, Leyla aims to inspire listeners to not only live longer lives but to enjoy better health and vitality.

This podcast comes from this blog post: Autophagy, Oxidative Stress, and the Mitochondria Discover more Christian podcasts at lifeaudio.com and inquire about advertising opportunities at lifeaudio.com/contact-us.

In this episode of the Heal Nourish Grow podcast, Dr. Chris Rhodes, a nutrition scientist, discusses his journey into the fields of longevity and fasting. He explains the significance of autophagy and shares his personal experiences with fasting. Dr. Rhodes also introduces Mimio, a product designed to mimic the benefits of fasting at the molecular level, and discusses the clinical studies that support its efficacy. The conversation delves into the science behind Mimeo's ingredients and their roles in promoting healthspan and longevity. Visit Mimio to learn more and get an awesome discount! Takeaways Fasting can activate longevity bio programs within our cells. Autophagy is a crucial process for cellular health and longevity. GLP-1 drugs like Ozembic may positively impact longevity pathways. Mimeo is designed to mimic the benefits of fasting without actual fasting. Clinical studies show Mimeo can improve metabolic health markers. The formulation of Mimeo includes powerful anti-aging molecules. Nicotinamide plays a key role in cellular energy and metabolism. Using Mimeo can enhance the benefits of shorter fasting periods. Maintaining a balance between mTOR activation and fasting pathways is essential for health. https://youtu.be/CidbXEJcj3k Episode transcript Cheryl McColgan (00:00.834)Hey everyone. Welcome to the Heal Nourish Grow Podcast. I don't even know the name of my own podcast. It's loving my words today. But anyway, I'm really excited about today's guest. I'm here with Dr. Chris Rhodes and he is a nutrition scientist. I'll let him better describe himself, but you will have heard his full bio, of course, before this, but I always like to start out, Dr. Rhodes, with just having you kind of share in your own words, what brought you into this space? What made you passionate about working with Mimeo Health and the technology there. Like what led you to this point? Dr. Chris Rhodes (00:32.962)Yeah, great question. Really happy to be here, Cheryl. Thanks for having me on. really got me interested into the longevity space, the healthy aging space, and eventually the fasting space was coming out of college. I got my BS in biochemistry from Leroy LaMaria Mount University, but like a lot of college kids didn't really know what I wanted to do there. So to try and figure that out, took an immunology fellowship at Stanford, just kind of pouring through all the research I could get my hands on going to all these seminars, and eventually came across the longevity research. And I thought that was so fascinating because it was this thing that used to be relegated to myth and legend, right? It was like Ponce de Leon and the Fountain of Youth. And now it's this very active, very rigorous area of scientific research with a ton of funding and a ton of companies and a ton of government and scientific attention on it. And it's one of those things that helps with everything, right? If you can solve aging, then you can pretty much also solve disease because by and large, most young folks don't get disease. really see that aging is something that's an underlying factor in every disease that happens. So if you can tackle these fundamental issues of aging at the cellular level and really slow that process down, then you can not only potentially enhance lifespan but also healthspan at the same time, which I think is what we're all really going for, living our lives as well as possible and as best health as possible for as long long as we can. When you're in the healthy aging and longevity space, eventually you come across fasting because fasting is one of the only ways that we know of to reliably extend lifespan and health span helps to treat, prevent, or delay most major diseases. And the reason why that was so fascinating to me is because it does all of that without actually adding anything into the system, right? So it's not this superfood or this wonder drug that's doing al...

In this video, we're breaking down the benefits hour by hour at critical milestones—14, 16, 24, 30, 36, 48, and 72 hours—so you can understand the science of fasting and how it helps you burn fat, boost brain health, and reset your metabolism. Now, let's jump into the timeline! ⏳ 14 Hours: Fat Storage Hormone (Insulin) Drops

In this episode of Hart2Heart, host Dr. Mike Hart dissects the science of aging and how to slow it down by optimizing cellular health. He breaks down two key strategies: autophagy and senolysis. Autophagy, the body's process of clearing out damaged cells, can be activated through fasting, cold plunges, sauna therapy, and high-intensity interval training. Dr. Hart also shares key supplements that promote autophagy. Senolysis focuses on eliminating ‘zombie' cells, damaged cells, that contribute to aging and inflammation. Dr. Hart explains how this process can be enhanced through similar lifestyle strategies and specific supplements like fisetin and quercetin. Show Notes: (0:00) Welcome back to the Hart2Heart Podcast with Dr. Mike Hart    (0:15) Dr. Hart introduces today's topic - How to slow againg (0:45) Understanding aging at the cellular level (2:30) Strategy #1: Autophagy - The body's self cleaning process  (4:00) Optimal benefits of fasting  (5:00) Behavioral factors to induce autophagy  (7:00) Benefits of ketosis for anti-aging  (9:15) Supplements to induce autophagy  (21:30) Strategy #2: Senolysis - eliminating “zombie” cells (22:45) Behavioral factors for Senolysis (25:00) Benefits of sauna for aging  (26:30) Benefits to cycle to clear our zombie cells (30:00) Closing thoughts Supplements/Resources Mentioned: Where to buy Supplements - iHerb  Spermidine - Mimics fasting effects and promotes cellular regeneration. Berberine - Helps regulate blood sugar and may mimic Metformin's longevity benefits. Quercetin - An antioxidant that supports immune health and autophagy. Resveratrol - Found in red wine, linked to longevity and anti-aging benefits. Curcumin - Anti-inflammatory compound from turmeric; supports brain and joint health. EGCG (from Green Tea) - May boost autophagy but could impact testosterone levels. Boron - Reduces inflammation and increases free testosterone by lowering SHBG. Fisetin - A flavonoid that helps remove senescent (zombie) cells and reduces inflammation.  --- Dr. Mike Hart is a Cannabis Physician and Lifestyle Strategist. In April 2014, Dr. Hart became the first physician in London, Ontario to open a cannabis clinic. While Dr. Hart continues to treat patients at his clinic, his primary focus has shifted to correcting the medical cannabis educational gap that exists in the medical community.  Connect on social with Dr. Mike Hart: Social Links: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

Ethan Suplee welcomes Kevin Smith back to American Glutton for an insightful conversation about weight loss, loose skin, intermittent fasting, and long-term health. Kevin shares his experience with fasting, autophagy, and how he manages his weight on a vegan diet. They dive into the realities of excess skin after significant weight loss, the myths around fat loss, and the mental challenges of maintaining a healthy lifestyle. Packed with humor and real talk, this episode is a must-listen for anyone on a weight loss journey.SHOW HIGHLIGHTS:00:02 - Introduction and welcome01:08 - Kevin on Ethan's podcast growth02:17 - Ethan's cameo in Clerks III03:13 - Loose skin and the challenges of weight loss06:03 - Autophagy and the benefits of fasting08:37 - Why fasting won't fix loose skin12:59 - Struggles with food addiction19:34 - Finding moderation in eating27:20 - Why exercise alone isn't enough for weight loss32:28 - Reflecting on past weight struggles38:57 - The challenge of hiking with weights40:47 - The science of weight loss through breathing46:52 - Improving fitness by tracking progress50:44 - Kevin's heart attack and life changes57:16 - Misconceptions about food and health01:02:10 - The importance of caloric deficit01:04:04 - Closing thoughts Hosted on Acast. See acast.com/privacy for more information.

In this episode of the Metabolic Freedom Podcast, we dive deep into the science of fasting and what happens inside your body during a 36-hour fast. From lowering insulin and tapping into fat-burning mode, to activating autophagy (cellular cleanup) and boosting brain-derived neurotrophic factor (BDNF), this fasting timeline unlocks powerful metabolic benefits. We explore: ✅ The first 14 hours: Lower insulin, burn glycogen, and experience energy diversion. ✅ 16-hour mark: Autophagy kicks in, clearing out damaged cells and enhancing fat burning. ✅ 24-hour mark: Digestive system reset with an intestinal stem cell reboot. ✅ 30-hour mark: BDNF production surges, improving brain function and mental clarity. ✅ 36-hour mark: Significant fat loss, increased ketone production, and a metabolic reset. Ben answers common fasting questions, including muscle loss concerns, what to drink, exercise during fasting, and the best way to break a 36-hour fast. Plus, hear about the longest fast ever recorded!

More good news about Omega-3s for heart health; Addressing early-stage dementia; When Lyme Disease doesn't respond to antibiotics; Ultra-processed food hijacks brain within days; Exosomes and adaptive deep-brain stimulation offer hope for Parkinson's; Psychologists conclude relentless “pursuit of happiness” may exhaust our brains' control centers; A common over-the-counter drug taken in pregnancy may hike offsprings' risk of ADHD. 

Episode #193 In this Fasting Q&A episode, hosted by Coach Lisa Chance, Dr. Jason Fung answers questions from the TFM Community: Are home-made smoothies and protein drinks helpful or detrimental as meal replacement when trying to lose weight or reverse type two diabetes? If so, what kind would you recommend? (05:14) Is it acceptable for someone 4'10” to eat 0.6 grams of protein per kilogram instead of TFM's recommended 0.8-1.2 gram, since they are so petite? (08:32) How does iodine intake and storage work in the body from a scientific perspective? Since iodine is water soluble, what is known about how long the body can maintain adequate iodine levels between dietary intake? Are there any established research findings about the need for iodine during different eating patterns, such as an extended fast? (12:02)  Will consistently high uric acid levels from fasting adversely affect my health even if I don't have symptoms of hyperuricemia? (14:08)  I believe you addressed this at the time Dr. Peter Attia was a guest on Thomas DeLauer's YouTube channel, but I can't remember which one of our podcasts that was. Wasn't he cautioning about extended fasts and muscle loss for people who were already in great shape - “shredded” if you will? Don't you quickly regain any muscle lost once you start eating nutrient-dense food again? (15:21) Is there more autophagy happening during exercise or fasting? (21:17) What is the best fasting regime for someone with a low BMI but who has non-alcoholic fatty liver disease? How long should alternate-day fasting (just started two 42-48 hour fasts a week) combined with a whole-food, low-carb diet continue? (23:46) What are your thoughts on fasting while taking ADHD medication? (25:04) Do you have any recommendations for a diet that will starve or kill cancer? (26:23) How long does it take to reverse insulin resistance while doing fasting and low-carb and how do you know when you have? (27:42) Please note that you need to be a member of the TFM Community to submit questions to the Q&A webinars with Dr. Fung but you can submit questions to our regular Q&A episodes here: https://bit.ly/TFMPodcastQs LINKS The two videos from the Fasting & Longevity Summit mentioned in this episode can be found here: Dr Ben Bikman - https://youtu.be/3GKiT2Ihek8?si=IHDMFHN3xpp4sEIf Dr Brian Lenzkes - https://youtu.be/Qqi8sumxGZY?si=p2QvYcCIjnk_vDLC   CHAPTERS: 00:00 Disclaimer 05:14 Smoothies as meal replacements 08:32 Protein allowance 12:02 Iodine intake 14:08 High uric acid levels 15:21 Muscle loss 21:17 Autophagy from exercise vs fasting 23:46 ADF for low BMI and NAFLD 25:04 Fasting while on ADHD medication 26:23 Diet to starve/kill cancer 27:42 How long to reverse insulin resistance   Transcripts of all episodes are available at www.thefastingmethod.com on the Podcast page. Learn More About Our Community: https://www.thefastingmethod.com Join our FREE Facebook Group: https://bit.ly/TFMNetwork Watch Us On YouTube: https://bit.ly/TFMYouTube Follow Us on Instagram: @fastingmethod   This podcast is for educational purposes only and is not a substitute for professional care by a doctor or other qualified medical professional. You should always speak with your physician or other healthcare professional before doing any fasting, changing your diet, taking or adjusting  any medication or supplements, or adopting any treatment for a health problem. The use of any other products or services purchased by you as a result of this podcast does not create a healthcare provider-patient relationship between you and any of the experts affiliated with this podcast. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.

Welcome to the Triple P Life Podcast! In this episode, Dr. Jay LaGuardia delves into the alarming rise of metabolic syndrome and its devastating impact on cellular health, hormonal balance, and overall well-being. We explore the complex factors contributing to this epidemic, including dietary changes, environmental toxins, and the down-regulation of our metabolic rates. The host challenges conventional wisdom about calorie restriction and exercise, highlighting the crucial role of basal metabolic rate and the detrimental effects of polyunsaturated fats. Dr. Jay outlines the seven key dysfunctions caused by metabolic insufficiency and offers practical, actionable strategies for reversing this trend, emphasizing the importance of nutrition, exercise, sleep, and targeted supplementation.   Episode Takeaways: Metabolic syndrome (affecting 80% of adults) drastically raises the risk of heart disease, stroke, and type 2 diabetes. Key signs: abdominal obesity, high blood pressure/sugar/triglycerides, low HDL cholesterol. Obesity's rise isn't just calories or inactivity; declining BMR (calories burned at rest) is crucial. This is linked to more PUFA consumption and environmental toxins. Metabolic insufficiency causes 7 key problems: mitochondrial dysfunction, insulin resistance, chronic inflammation, lipotoxicity, glycation, hormonal disruption, and autophagy suppression. These fuel fatigue, weight gain, disease risk, aging, and imbalances. Reversal needs a holistic approach: time-restricted eating, prioritizing protein/healthy fats, managing carbs, regular exercise (zone 2 & HIIT), cold/sauna, and hormone balance. Genes aren't destiny. Lifestyle heavily influences gene expression. Healthy habits and addressing metabolic dysfunction's root causes put you in control.   Chapters: 00:00 - Introduction and Feedback Recap 02:30 - Understanding Metabolic Syndrome 05:45 - The Role of Diet and Lifestyle 09:00 - The Obesity Epidemic in America 12:15 - Historical Caloric Intake vs. Modern Times 15:30 - The Impact of Metabolic Rate Changes 18:45 - Environmental Toxins and Metabolism 22:00 - The Consequences of Metabolic Downregulation 25:15 - Cellular Dysfunction and Aging 28:30 - Insulin Resistance and Chronic Inflammation 31:45 - Lipotoxicity and Glycation Explained 35:00 - Hormonal Disruption and Autophagy 38:15 - Solutions for Metabolic Dysfunction 41:30 - Restoring Metabolic Health: Key Strategies 44:45 - Outro and Upcoming Topics Find all things Triple P Life by visiting the website. Follow Dr. Jay: Facebook | LinkedIn | YouTube Get Dr. Jay's Book: Change Your Mind Change Your Destiny Find all the nutrition and supplement products Triple P Nutrition has to offer here.

Support the D.A.W.G.Z. @ patreon.com/MSsecretpod Support Kiss @ https://www.patreon.com/stuffisland Go See Matt Live @ mattmccusker.com/dates Go See Shane Live @ shanemgillis.com Yo0o0o0o0o0o0o0. Another fambly ep but we got the kiss man here this week. Matt fasted for over 48hrs. Broke fast right before we started. Hot ass mf cast. Please enjoy. God Bless.  Download the PrizePicks app or visit https://prizepicks.onelink.me/LME0/DRENCHED today and use code Drenched to get $50 instantly after you play your first $5 lineup Try BlueChew FREE when you use our promo code DRENCHED at checkout - just pay $5 shipping. That's bluechew.com/, promo code DRENCHED to receive your first month FREE.

Intermittent fasting with early (9:00-5:00) eating window works best for weight loss, blood sugar control; Beleaguered California Governor Newsom at least gets it right with initiative to curb ultra-processed food, dyes, sugar; Can supplements still be used after their expiration dates? Long-term use of acid-blockers hikes heart risks in women; Quality of patient care threatened by private equity takeovers of hospitals; A tiny camera that you swallow reveals problems lurking deep within the small intestine; High fructose corn syrup fuels tumor growth; RFK Jr. faces congressional grilling next week. 

***JOIN THE NEXT MASTER YOUR FASTING CHALLENGE THAT STARTS Jan 29th, 2025!*** We'll GUIDE you how to FAST to LOSE FAT for good, and use 'fast cycling' to achieve uncommon results! REGISTER HERE! Click the Link for DATES, DETAILS, and FAQs! In this practical episode, Dr. Scott Watier and Tommy Welling address the common challenges of returning to fasting after the holiday season, providing actionable strategies for regaining momentum and achieving consistent results. They tackle listener questions about breaking through the 24-hour fasting plateau, offering a strategic approach to extending fasting windows while maintaining sustainable practices. The hosts dive deep into the science behind feeling cold during fasting, explaining the metabolic adaptations taking place and providing practical solutions for managing temperature changes. They round out the episode by addressing protein optimization and the role of autophagy in skin health during weight loss, delivering valuable insights for those seeking to maintain their fasting lifestyle long-term. Take the NEW FASTING PERSONA QUIZ! - The Key to Unlocking Sustainable Weight Loss With Fasting! Resources and Downloads: SIGN UP FOR THE DROP OF THE ULTIMATE GUIDE TO BLOOD SUGAR CONTROL GRAB THE OPTIMAL RANGES FOR LAB WORK HERE! - NEW RESOURCE! - December 2024 FREE RESOURCE - DOWNLOAD THE NEW BLUEPRINT TO FASTING FOR FAT LOSS! SLEEP GUIDE DIRECT DOWNLOAD DOWNLOAD THE FASTING TRANSFORMATION JOURNAL HERE! Partner Links: Get your FREE BOX OF LMNT hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase here! Get 30% off a Keto-Mojo blood glucose and ketone monitor (discount shown at checkout)! Click here! Our Community: Let's continue the conversation. Click the link below to JOIN the Fasting For Life Community, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply! If you enjoy the podcast, would you please tap on the stars below and consider leaving a short review on Apple Podcasts/iTunes? It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them!

MUSINGS

Episode Highlights With KatieThe reasons I started to do a yearly water fastMy own experiences with fastingWhat I think about fasting in general, for women, and what I doMy longest fasts and what this one will likely beThe mental and inner work of a fast and the real reason I do itGratitude journaling when I feel the desire for food and separating desire/pleasure from joy/gratitudeIt is not for everyone, but it's helpful for meKetosis and autophagy as beneficial statesResources MentionedBeam Minerals - Use code wellnessmama for a discountActivated SaltMan's Search for Meaning by Viktor E. FranklAwareness by Anthony De MelloPower vs Force by Dr. David R. Hawkins

This episode is brought to you by Bioptimizers, Bon Charge, and AquaTru. Social media is flooded with weight loss advice, much of which is unhelpful or unsustainable. From crash diets to quick-fix methods that rarely lead to lasting results, it's hard to cut through the noise and find what truly works. Today's guest shares expert advice and the proven strategies he uses with his clients to achieve real, lasting results. Today on The Dhru Purohit Show, Dhru sits down with nutritionist and certified personal trainer Dr. Allan Bacon. Dr. Bacon breaks down the best and worst ways to lose weight, the ideal mindset for sustained weight loss, and the harmful advice often targeted at women in perimenopause and menopause. He also shares actionable tips on how often to train and strategies for changing eating habits and behaviors around weight loss. From debunking social media myths to diving deep into the latest research, Dr. Bacon offers expert insights on nutrition and training you won't want to miss. Dr. Allan Bacon holds a Doctorate in Dental Surgery from the University of Maryland. He is a certified personal trainer through the National Academy of Sports Medicine, a certified nutritionist and physique/bodybuilding coach, a USA Powerlifting coach, and has over 15 years of experience formulating for leading dietary supplement companies. His work has been featured in Muscle & Fitness, Sci-Fit, the Alan Aragon Research Review, and The Personal Trainer Development Center. Dr. Bacon specializes in helping working adults master their physique, performance, mindset, and habits to achieve sustainable, lifelong results. In this episode, Dhru and Dr. Bacon dive into: Best and worst ways to lose 10 lbs (00:00:36) Optimal mindset for sustained weight loss (6:46) Why weight loss becomes more challenging as we age (17:28) Damaging advice for women in menopause (24:50) Changing strategies (31:34) The power of resistance training and what the research shows (36:57) Autophagy through exercise, how to get started, and why fasting can be harmful (46:57) Ideal protein intake and the nuances that need to be considered (54:09) Minimum amount of training to build lean muscle (01:01:01) What is resting metabolic rate and the impact on calories (1:09:57) The Twin study and Three Aspects of every habit (1:12:57) Dr. Bacon's journey and nutrition guidance (1:28:27) How to incorporate movement into your day (1:37:57) Dr. Bacon's Why (1:43:07) Also mentioned in this episode: Dr. Allan Bacon's Nutrition Guide E-book: Learn how to optimize your diet to get stronger, improve your health, build balanced meals, make smart choices at restaurants, stay on track during vacations, and more. For more on Dr. Bacon, follow him on Instagram, Facebook, YouTube, and his Website. This episode is brought to you by Bioptimzers, Bon Charge, and AquaTru.  Go to bioptimizers.com/dhru now and enter promo code DHRU10 to get 10% off any order and free gifts for a limited time. Right now, BON CHARGE is offering my community 15% off; just go to boncharge.com/DHRU and use coupon code DHRU to save 15%. Black Friday sale ends December 4th. AquaTru is a countertop reverse osmosis purifier with a four-stage filtration system that removes 15x more contaminants than the bestselling water filters out there. Go to dhrupurohit.com/filter/ and get $150 off when you try AquaTru for yourself. Learn more about your ad choices. Visit megaphone.fm/adchoices