Podcasts about Neuropharmacology

For a captioned version or to access the transcript, please visit: https://www.pharmaron.com/knowledge-center/dmpk-insights-12-bbb-transporters/In this podcast, Elena and Mikko will discuss the current state-of-the-art around transporter sub-types and their expression within the blood-brain barrier (BBB) and opportunities for utilizing these transporters for brain drug delivery. We will address the following questions: Current knowledge of BBB transporters in health and disease Approaches to utilize BBB transporters for brain drug delivery What to consider while developing transporter-mediated drug delivery systems to the brain Future development (anticipated and required) to further the fieldOur Speakers:Dr. Elena Puris – Academic Research Fellow and Associate Professor in Neuropharmacology at the University of Eastern FinlandDr. Elena Puris is an associate professor of neuropharmacology and senior researcher at the University of Eastern Finland. During her PhD at the University of Eastern Finland and postdoctoral research at Heidelberg University, Elena developed a strong interest in blood-brain barrier transporters and their roles in drug delivery and disease pathogenesis. She has a multidisciplinary background in drug development and over 15 years of experience in academia and the pharmaceutical industry. Elena's main research focus is membrane transporters and their impact on drug delivery and biochemical processes in health and pathological conditions.Dr. Mikko Gynther – Senior Researcher and Associate Professor in Biopharmacy at the University of Eastern FinlandDr. Mikko Gynther is an associate professor of biopharmacy and senior researcher at the School of Pharmacy, University of Eastern Finland. He obtained his PhD in pharmacy at the University of Eastern Finland on utilizing glucose and amino acid transporters for the CNS delivery of prodrugs. He has extensive experience spanning 20 years in transporter-mediated drug delivery and pharmacokinetics research. Mikko's current research is focused on transporter-mediated drug delivery into the brain and cancer cells and utilizing proteomics to investigate disease-induced changes in drug transporters and enzymes.Stay tuned for more podcasts in our Pharmaron DMPK Insights Series!

Fri, 24 Jan 2025 00:00:00 +0000 https://seesee.podigee.io/s3e12-john-cryan f9d417dd4b9c1419db8383f62238f1f5 In this episode, we embark on a fascinating journey to explore one of the most groundbreaking areas of science - the gut-brain axis! Leading the way is none other than world-renowned neuroscientist Professor John Cryan of University College Cork, whose pioneering work has helped uncovered the powerful link between the gut microbiome and mental health and behaviour. Co-hosted by one of Europe's leading neurosurgeons, Peter Vajkoczy, this is one episode you won't want to miss. So, sit back and buckle up as we navigate the neural pathways that connect our gut to our brain, and discover how this connection plays a critical role in a wide range of conditions, from mental disorders to degenerative diseases. We'll delve into Professor Cryan's cutting-edge research, exploring the diseases his team in Cork are targeting and the innovative delivery systems they're developing to make genetic changes in the brain. You'll also hear about the forces that shape our microbiota throughout our lives, from the importance of vaginal birth and breast milk to the relationship between stress, dementia and depression, and the impact of diet on social behaviour, cognitive decline and aging, and mental health. We'll also explore the exciting new field of psychobiotics, which Cryan covers in his bestselling book, “The Psychobiotic Revolution: Mood, Food and the New Science of the Gut-Brain Connection”. Prepare to be amazed by the potential future treatments for neurological and mental health conditions through the lens of microbiota and neuroscience. Join us for an unforgettable episode as microbes and neurons bring us closer to understanding a shared universe of the gut and the brain! *Professor John F. Cryan is Vice-President for Research and Innovation at University College Cork (UCC), Professor in the Department of Anatomy and Neuroscience, and Principal Investigator at the APC Microbiome Ireland Institute. His pioneering research concentrates on the gut-brain axis and the impact of gut microbes on stress, psychiatric and immune disorders, as well as their influence on mental health. He is a leading figure in this field, with numerous influential publications and significant contributions to scientific research and public understanding of the microbiome. He has published over 600 peer-reviewed articles and has served as co-editor for several books. Additionally, he currently serves as Editor-in-Chief of Neuropharmacology and Neurobiology of Stress, and is a member of the editorial boards of 15 other scientific journals. **This episode is cohosted by Prof. Peter Vajcokzy. He has been Head of Neurosurgery at Charité-Universitätsmedizin in Berlin since 2007. He leads 5,000 brain surgeries a year, 800 of which he performs. He is a full professor at Charité and an associate professor at Heidelberg. He treats cerebrovascular disorders, brain tumours, skull base tumours and performs minimally invasive spine and peripheral surgery. He also performs functional neurosurgery and pain management procedures. His research focuses on brain cancer and the mechanisms of brain tumours. He also studies the monitoring of neocortically ill patients after vessel occlusion. https://publish.ucc.ie/researchprofiles/C003/jcryan Social Media: John F. Cryan (@jfcryan) · X https://scholar.google.com/citations?user=3SiQStcAAAAJ&hl=en https://www.amazon.com/Books-John-F-Cryan/s?rh=n%3A283155%2Cp_27%3AJohn+F.+Cryan TEDMED Food for thought: How gut microbes change your mind https://www.youtube.com/watch?v=kMVxbnfSP-Q Feed Your Microbes - Nurture Your Mind | John Cryan | TEDxHa'pennyBridge https://www.youtube.com/watch?v=vKxomLM7SVc NETFLIX Documentary: “Hack your Health” featuring Prof. John Cryan https://www.netflix.com/tudum/articles/hack-your-health-secrets-of-your-gut-release-date-trailer-news Grandmaternal stress and during pregnancy and DNA Germany/ Brazil and Sweden) (Paper published in 2017 Serpeloni F, Radtke K, de Assis SG, Henning F, Nätt D, Elbert T. Grandmaternal stress during pregnancy and DNA methylation of the third generation: an epigenome-wide association study. Transl Psychiatry. 2017 Aug 15;7(8):e1202. doi: 10.1038/tp.2017.153. PMID: 28809857; PMCID: PMC5611722. https://pubmed.ncbi.nlm.nih.gov/28809857/ 3 12 full no Gut-brain axis,Gut Microbiome,Microbiome,Mental health,Neuroscience,Neurobiology,Gut-brain connection,Psychobiotics,Neurodegenerative diseases,Microbiota Dr. Cecilia Ponce Rivera

Welcome to Paranormal Spectrum, where we illuminate the enigmatic corners of the supernatural world. I'm your host, Barnaby Jones, and today we have a very special guest joining us:Bruce Rapuano a B.A. degree from the University of Pennsylvania where he majored in Neurobiology and minored in Psychology, a Ph.D. in Neuropharmacology from the University of Connecticut and a J.D. from New York Law School. Dr. Rapuano has conducted independent biomedical research as a cell biologist at internationally recognized medical institutions including the Memorial Sloan-Kettering Cancer Center and the Hospital for Special Surgery, both located in New York City. He has authored or coauthored thirty scientific articles in peer-reviewed medical journals. He has published articles on topics such as the role of membrane phospholipids in nerve function, the skeletal effects of cancer metastases, metabolic bone diseases and the coordinate surface electrical and biological properties of titanium alloy implant materials. Dr. Rapuano has also worked concurrently as a medical research scientist and Associate Radiation Safety Officer at the Hospital for Special Surgery.This bombshell nonfiction book, recently discussed by the author with George Knapp on Coast to Coast AM, is the only first-person account to date of UFO alien abductions authored by a mainstream American scientist. The author, who has multiple degrees in neuroscience, goes on the record regarding his incredible and fascinating experiences with UFO close encounters, including a very close encounter during which he was abducted from a group of eight other witnesses, interactions with alien beings and an unexplained nasal implant of specific structure all of which were consciously recalled without regressive hypnosis. The detailed conscious recollection of these experiences, including unexplained physiological effects and physical scars, checks every box in the modern core alien abduction scenario AND predated the publishing of any other books on alien abduction. Another remarkable aspect to this book is the fact that it is the first to explain exactly how the grey aliens were genetically reengineered from our early hominin ancestors. Also riveting are the author's interactions with short humanoid beings that are described in captivating detail to reveal all the ways that aliens control human behavior during the abduction process possibly with the aid of neural implants.This is the story of a mainstream scientist's own interactions with the highly advanced alien beings who abducted him and at least thousands of other people. As discussed in Dominion Lost, compelling technological evidence of the alien presence, especially with respect to incredibly advanced UFO propulsion systems and implanted devices that are likely instruments of mind control, has existed on this planet for more than 60 years. More importantly, this book is a wake-up call to our species to finally accept the reality that we are now sharing our world with technologically superior alien beings. This new reality must be addressed immediately.https://www.amazon.com/DOMINION-LOST-Abridged-Bruce-Rapuano/dp/B0CQGDXV8NClick that play button, and let's unravel the mysteries of the UNTOLD! Remember to like, share, and subscribe to our channel to stay updated on all the latest discoveries and adventures. See you there!Join Barnaby Jones on the Paranormal Spectrum every Thursday on the Untold Radio Network Live at 12pm Central – 10am Pacific and 1pm Eastern. Come and Join the live discussion next week. Please subscribe.We have twelve different Professional Podcasts on all the things you like. New favorite shows drop each day only on the UNTOLD RADIO NETWORK.To find out more about Barnaby Jones and his team, (Cryptids, Anomalies, and the Paranormal Society) visit their website www.WisconsinCAPS.comMake sure you share and Subscribe to the CAPS YouTube Channel as wellhttps://www.youtube.com/channel/UCs7ifB9Ur7x2C3VqTzVmjNQ

References Guerra, Daniel J. 2024 Biochemistry lecture archives Cells.2019 Nov 12;8(11):1424 Front Cell Neurosci 2017 Feb1;11:14. Neuropharmacology 2014.79, April : 1-9 Front Mol Neurosci. 2024 May 22;17:1389100. Byrds. 1971. Byrdmaniax lp https://youtu.be/SEBecV36esY?si=wtSnoWe-fAHZzbNv Porter and Fletcher.1934 "Don't Fence Me In" Bing Crosby and Andrew Sisters (1945) https://youtu.be/ILyuEtGrMwI?si=WpBi9KG9m7dzufW4 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

In this special extended podcast we have three guests in our virtual studio to examine whether we're getting the messaging about Parkinson's right, be it reporting research findings or at a patient appointment.  With the help of Prof David Dexter, Director of Research at Parkinson's UK and Professor of Neuropharmacology at Imperial College London, Dr Angus Macleod, Honorary Consultant Neurologist at NHS Grampian and Clinical Senior Lecturer at the University of Aberdeen, and former broadcast and print journalist Iain Stephen Morrison, who is the Media and Communications Officer for Parkinson's UK in Scotland, we discuss the difficulties of painting a realistic picture whilst remaining mindful of feelings and still preserving hope. We tackle some difficult topics including prognosis and the mixed messaging surrounding whether one dies with or from Parkinson's, and examine bias in research participation, publicity and public awareness campaigns. 

Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Elena Martín-García and Professor Rafael Maldonado from the Laboratory of Neuropharmacology, Pompeu Fabra University and Hospital del Mar Research Institute, Barcelona, Spain and Professor Jose Manuel Fernández-Real from the Endocrinology, Nutrition, Eumetabolism & Health group, Hospital Trueta of Girona, University of Girona, Girona, Spain on the paper "Gut microbiota signatures of vulnerability to food addiction in mice and humans" published in paper copy in Gut in November 2024. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).

Ep 148 - A Scientist's own Alien Abduction Encounters - Dr Bruce Rapuano This is the story of a mainstream scientist's own interactions with the highly advanced alien beings who abducted him and at least thousands of other people. As discussed in Dominion Lost, compelling technological evidence of the alien presence, especially with respect to incredibly advanced UFO propulsion systems and implanted devices that are likely instruments of mind control, has existed on this planet for more than 60 years. More importantly, this book is a wake-up call to our species to finally accept the reality that we are now sharing our world with technologically superior alien beings. This new reality must be addressed immediately.Bruce Rapuano a B.A. degree from the University of Pennsylvania where he majored in Neurobiology and minored in Psychology, a Ph.D. in Neuropharmacology from the University of Connecticut and a J.D. from New York Law School. Dr. Rapuano has conducted independent biomedical research as a cell biologist at internationally recognized medical institutions including the Memorial Sloan-Kettering Cancer Center and the Hospital for Special Surgery, both located in New York City. He has authored or coauthored thirty scientific articles in peer-reviewed medical journals. He has published articles on topics such as the role of membrane phospholipids in nerve function, the skeletal effects of cancer metastases, metabolic bone diseases and the coordinate surface electrical and biological properties of titanium alloy implant materials. Dr. Rapuano has also worked concurrently as a medical research scientist and Associate Radiation Safety Officer at the Hospital for Special Surgery.Buy Dominion Lost on Amazon: https://amzn.to/3YruTBMTitle music provided by Steve Yarwood and Ambienfinity

Tony Altar, President and COO of Splice Therapeutics, returns to The Bioinformatics CRO Podcast to discuss the present and future of neuropharmacology, skateboarding, and how to make the most of your health and career.  The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https://www.bioinformaticscro.com/

Bruce Rapuano a B.A. degree from the University of Pennsylvania where he majored in Neurobiology and minored in Psychology, a Ph.D. in Neuropharmacology from the University of Connecticut and a J.D. from New York Law School. Dr. Rapuano has conducted independent biomedical research as a cell biologist at internationally recognized medical institutions including the Memorial Sloan-Kettering Cancer Center and the Hospital for Special Surgery, both located in New York City. He has authored or coauthored thirty scientific articles in peer-reviewed medical journals. He has published articles on topics such as the role of membrane phospholipids in nerve function, the skeletal effects of cancer metastases, metabolic bone diseases and the coordinate surface electrical and biological properties of titanium alloy implant materials. Dr. Rapuano has also worked concurrently as a medical research scientist and Associate Radiation Safety Officer at the Hospital for Special Surgery.Become a supporter of this podcast: https://www.spreaker.com/podcast/night-dreams-talk-radio--2788432/support.

Investigadores italianos concluem que misturar bebidas energéticas e alcoólicas durante a adolescência pode provocar danos que se prolongam até á idade adulta. Publicado na Neuropharmacology

Durante algún tiempo la ciencia anduvo detrás de la investigación en el cerebro sobre dónde y cómo funcionaban los/el centro del placer. Algunos científicos estuvieron cerca de descubrirlo pero en algunos famosos casos, el motivo por el cual justificaban su investigación alteraron los resultados, aunque en realidad nunca fueron suficientemente concluyentes. Incluso las agencias de inteligencia de algunos países se centraron en ello, con el objetivo de controlar a los sujetos o la población. Hoy en día parece que esta investigación se abandonó, pero como siempre podría ser que se continúe en el más absoluto secreto. ¿Existe un Centro del Placer en el Cerebro? El concepto del “centro del placer” en el cerebro ha capturado la imaginación de científicos, filósofos y el público general durante décadas. ¿Es posible que una región específica del cerebro sea responsable de las sensaciones de placer? La respuesta es más compleja y matizada de lo que podría parecer a primera vista. 1. Orígenes del Concepto: Experimentos Pioneros En los años 50, los investigadores James Olds y Peter Milner descubrieron áreas del cerebro que, al ser estimuladas eléctricamente, producían respuestas de comportamiento asociadas con el placer en ratas de laboratorio. Olds y Milner implantaron electrodos en el cerebro de estas ratas y notaron que los animales repetían conductas dirigidas a la autoadministración de la estimulación eléctrica. Estos hallazgos llevaron a la identificación del sistema de recompensa del cerebro, un conjunto de estructuras cerebrales que parecía mediar el placer y la motivación . 2. El Sistema de Recompensa: Un Mosaico de Placer El sistema de recompensa incluye varias regiones clave, entre ellas: • Área Tegmental Ventral (ATV): Produce dopamina, un neurotransmisor crucial en la experiencia del placer. • Núcleo Accumbens: Recibe señales dopaminérgicas del ATV y está implicado en la evaluación de recompensas y la motivación. • Amígdala: Procesa la emoción y puede influir en la experiencia del placer. • Corteza Prefrontal: Involucrada en la toma de decisiones y la regulación de impulsos relacionados con recompensas. Este sistema forma una red de estructuras interconectadas, más que un único “centro del placer”. La dopamina juega un papel central, no solo en la percepción del placer sino también en la anticipación de recompensas . 3. Más Allá de la Dopamina: Una Perspectiva Multifactorial Aunque la dopamina ha sido tradicionalmente asociada con el placer, investigaciones recientes sugieren que su papel es más complejo. La dopamina parece estar más relacionada con la motivación y el aprendizaje de recompensas que con la sensación directa de placer . En otras palabras, la dopamina ayuda a predecir y buscar recompensas, pero el placer experimentado podría depender de otras sustancias neuroquímicas, como la serotonina y los opioides endógenos. 4. Placer, Motivación y Conducta: Un Entrelazado Complejo El placer no es una experiencia monolítica; varía según el contexto, la persona y la situación. La distinción entre “querer” (motivación) y “gustar” (placer) es fundamental en la neurociencia actual. Los estudios muestran que las áreas cerebrales que mediatizan el “querer” (como el núcleo accumbens) pueden diferenciarse de aquellas que mediatizan el “gustar” (como la corteza insular). Esta dicotomía subraya que el placer y la motivación, aunque relacionados, no son sinónimos . 5. Aplicaciones y Repercusiones Clínicas La comprensión del sistema de recompensa tiene implicaciones prácticas significativas. Trastornos como la depresión y la adicción están estrechamente relacionados con disfunciones en estas vías. Por ejemplo, la depresión puede implicar una hipofunción del sistema de recompensa, resultando en una incapacidad para experimentar placer, conocida como anhedonia . La adicción, por otro lado, puede estar marcada por una hiperactividad dopaminérgica, llevando a una búsqueda compulsiva de recompensas a pesar de las consecuencias negativas. 6. Nuevas Fronteras en la Investigación del Placer La investigación sobre el placer cerebral sigue avanzando. Las técnicas de neuroimagen y la genética están revelando detalles más precisos sobre cómo diferentes regiones y neurotransmisores interactúan para generar la experiencia de placer. Estudios recientes han comenzado a explorar cómo los factores sociales y ambientales modulan el sistema de recompensa, proporcionando una comprensión más holística de cómo el cerebro procesa el placer. 7. Conclusión: Un Viaje Multifacético Aunque la idea de un único “centro del placer” es atractiva, la realidad es que el placer es el resultado de una compleja interacción entre múltiples áreas cerebrales y sistemas neuroquímicos. En lugar de un solo centro, tenemos un sistema de recompensa que integra la anticipación, la experiencia y la motivación relacionadas con las recompensas. Esta red de estructuras y mecanismos es fundamental para nuestra comprensión del comportamiento humano y la búsqueda de la felicidad. El conocimiento sobre el sistema de recompensa y el placer cerebral es un campo dinámico y en evolución, prometiendo nuevas perspectivas sobre cómo experimentamos el mundo y buscamos la satisfacción en nuestras vidas. Referencias 1. Olds, J., & Milner, P. (1954). Positive reinforcement produced by electrical stimulation of septal area and other regions of rat brain. Journal of Comparative and Physiological Psychology, 47(6), 419. 2. Schultz, W. (2015). Neuronal Reward and Decision Signals: From Theories to Data. Physiological Reviews, 95(3), 853-951. 3. Berridge, K. C., & Kringelbach, M. L. (2015). Pleasure systems in the brain. Neuron, 86(3), 646-664. 4. Kelley, A. E., & Berridge, K. C. (2002). The neuroscience of natural rewards: relevance to addictive drugs. Journal of Neuroscience, 22(9), 3306-3311. 5. Der-Avakian, A., & Markou, A. (2012). The neurobiology of anhedonia and other reward-related deficits. Trends in Neurosciences, 35(1), 68-77. 6. Volkow, N. D., & Morales, M. (2015). The Brain on Drugs: From Reward to Addiction. Cell, 162(4), 712-725. 7. Koob, G. F., & Volkow, N. D. (2016). Neurobiology of addiction: a neurocircuitry analysis. The Lancet Psychiatry, 3(8), 760-773. 8. Nestler, E. J., & Luscher, C. (2019). The neurobiology of drug addiction: a neurocircuit perspective. Neuropharmacology, 76, 124-133. Otros temas en el programa: 40:55 John Williams 1:34:44 La cultura de la inmediatez 1:47:33 Carreras de Cuadrigas No soy el Señor Monstruo - Capítulo 15 Puedes leer más y comentar en mi web, en el enlace directo: https://luisbermejo.com/el-centro-del-placer-zz-podcast-05x47/ Puedes encontrarme y comentar o enviar tu mensaje o preguntar en: WhatsApp: +34 613031122 Paypal: https://paypal.me/Bermejo Bizum: +34613031122 Web: https://luisbermejo.com Facebook: https://www.facebook.com/ZZPodcast/ X (twitters): https://x.com/LuisBermejo y https://x.com/zz_podcast Instagrams: https://www.instagram.com/luisbermejo/ y https://www.instagram.com/zz_podcast/ Canal Telegram: https://t.me/ZZ_Podcast Canal WhatsApp: https://whatsapp.com/channel/0029Va89ttE6buMPHIIure1H Grupo Signal: https://signal.group/#CjQKIHTVyCK430A0dRu_O55cdjRQzmE1qIk36tCdsHHXgYveEhCuPeJhP3PoAqEpKurq_mAc Grupo Whatsapp: https://chat.whatsapp.com/FQadHkgRn00BzSbZzhNviThttps://chat.whatsapp.com/BNHYlv0p0XX7K4YOrOLei0

Die Themen in den Wissensnachrichten: +++ Ameisen behandeln Wunden +++ Wodka-E verändert das Gehirn langfristig +++ Bananenabfälle werden zu nachhaltigen Extensions +++**********Weiterführende Quellen zu dieser Folge:Wound-dependent leg amputations to combat infections in an ant society, Current Biology, 02.07.24Amputation in Camponotus maculatus (VIDEO), EurekAlert, 02.07.24Mixing energy drinks and alcohol during adolescence impairs brain function: A study of rat hippocampal plasticity, Neuropharmacology, 15.08.2024This start-up is making artificial hair from bananas, CNN, 03.07.24The Human Cost of Politicizing Immigration: Migration Stigma, US Politics, and Health, JAMA, 01.07.24Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: Tiktok und Instagram.

The Outer Realm Radio welcomes Dr. Bruce E. Rapuano Hosts: Michelle Desrochers Date: May 30th, 2024 Episode: 445 Discussion: Dr. Rapuano will be discussing his book " In Dominion Lost: A Scientist's Own Alien Abduction Encounters" Full disclosure by the US Government, touches in depth about his first memory of abduction at the age of 6, his thoughts on why Abductions are happening , Christian thoughts on aliens and so much more! Please Support us: Like, Subscribe, Share, Comment About Our Guest: Bruce Rapuano a B.A. degree from the University of Pennsylvania where he majored in Neurobiology and minored in Psychology, a Ph.D. in Neuropharmacology from the University of Connecticut, and a J.D. from New York Law School. Dr. Rapuano has conducted independent biomedical research as a cell biologist at internationally recognized medical institutions including the Memorial Sloan-Kettering Cancer Center and the Hospital for Special Surgery, both located in New York City. He has authored or coauthored thirty scientific articles in peer-reviewed medical journals. He has published articles on topics such as the role of membrane phospholipids in nerve function, the skeletal effects of cancer metastases, metabolic bone diseases and the coordinate surface electrical and biological properties of titanium alloy implant materials. Dr. Rapuano has also worked concurrently as a medical research scientist and Associate Radiation Safety Officer at the Hospital for Special Surgery. About The Book: -In Dominion Lost: A Scientist's Own Alien Abduction Encounters recently discussed by the author with George Knapp on Coast to Coast AM, Dr. Bruce E. Rapuano goes on the record. Dr. Rapuano, who has multiple degrees in neuroscience, describes his UFO close encounters, including one in which he was abducted from a group of eight other witnesses, as well as experiences with advanced non-human beings and an unexplained nasal implant of specific structure all of which were recalled without regressive hypnosis. Also described are the author's interactions with short humanoid beings that reveal all the ways that that the aliens appear to control human behavior during the abduction process. The book further explains : · How the implants that are frequently reported by abductees work to analyze and influence the activity of the human brain. · Exactly how the “grey aliens” were genetically reengineered from our early hominin ancestors. · Precisely how the UFO propulsion system creates gravitational wave energy. At the same time, relying on his professional background, insight from his personal abduction experiences and hundreds of cited scientific articles from peer-reviewed journals, the author demonstrates that the ultrasophisticated technical capabilities exhibited by the visitors to our planet are more than plausible. They represent a logical extrapolation of current human theoretical and applied science. Moreover, according to Rapuano, “ the powerful evidence of such technology which has existed for more than 60 years, especially with respect to incredibly advanced propulsion systems for interstellar space travel and implanted devices that are likely instruments of mind control, proves that the aliens are here. Potentially breakthrough scientific innovations underlying these highly advanced alien capabilities are revealed that make the book a de facto whistleblower report on the subject of UFO's and alien abduction. “ More importantly, this book, says Rapuano “ is a wake-up call to our species to finally accept the reality that we are now sharing our world with technologically superior non-human beings. This new reality must be addressed immediately. “ Reviews:“ A fantastic book that will make an impact on the field. ” – George Knapp. Mainstream American Scientist Bruce E. Rapuano Goes On the Record With His Own UFO Close Encounters and Alien Abduction Experiences In a Newly Released Book New York, NY – February 5, 2024 - A newly published nonfiction book is the only first-person account to date of multiple UFO close encounters and alien abductions authored by a mainstream American scientist Contact: dominionlost@gmail.com Links For more information, visit : Amazon.com: Dominion Lost: A Scientist's Own Alien Abduction Encounters - eBook : Rapuano, Bruce: Kindle Store, Amazon.com: DOMINION LOST - Abridged Version: A Scientist's Own Alien Abduction Encounters eBook : Rapuano, Bruce: Books and Facebook (https:// www.facebook.com / profile.php?id = 61553229350298). A formal disclaimer: The opinions and information presented or expressed by guests on The Outer Realm Radio are not necessarily those of the TOR Hosts, Sponsors, or the United Public Radio Network and its producers. We will however always be respectful and courteous to all involved. Thank you, we appreciate you all!

The Outer Realm Radio welcomes Dr. Bruce E. Rapuano Hosts: Michelle Desrochers Date: May 30th, 2024 Episode: 445 Discussion: Dr. Rapuano will be discussing his book " In Dominion Lost: A Scientist's Own Alien Abduction Encounters" Full disclosure by the US Government, touches in depth about his first memory of abduction at the age of 6, his thoughts on why Abductions are happening , Christian thoughts on aliens and so much more! Please Support us: Like, Subscribe, Share, Comment About Our Guest: Bruce Rapuano a B.A. degree from the University of Pennsylvania where he majored in Neurobiology and minored in Psychology, a Ph.D. in Neuropharmacology from the University of Connecticut, and a J.D. from New York Law School. Dr. Rapuano has conducted independent biomedical research as a cell biologist at internationally recognized medical institutions including the Memorial Sloan-Kettering Cancer Center and the Hospital for Special Surgery, both located in New York City. He has authored or coauthored thirty scientific articles in peer-reviewed medical journals. He has published articles on topics such as the role of membrane phospholipids in nerve function, the skeletal effects of cancer metastases, metabolic bone diseases and the coordinate surface electrical and biological properties of titanium alloy implant materials. Dr. Rapuano has also worked concurrently as a medical research scientist and Associate Radiation Safety Officer at the Hospital for Special Surgery. About The Book: -In Dominion Lost: A Scientist's Own Alien Abduction Encounters recently discussed by the author with George Knapp on Coast to Coast AM, Dr. Bruce E. Rapuano goes on the record. Dr. Rapuano, who has multiple degrees in neuroscience, describes his UFO close encounters, including one in which he was abducted from a group of eight other witnesses, as well as experiences with advanced non-human beings and an unexplained nasal implant of specific structure all of which were recalled without regressive hypnosis. Also described are the author's interactions with short humanoid beings that reveal all the ways that that the aliens appear to control human behavior during the abduction process. The book further explains : · How the implants that are frequently reported by abductees work to analyze and influence the activity of the human brain. · Exactly how the “grey aliens” were genetically reengineered from our early hominin ancestors. · Precisely how the UFO propulsion system creates gravitational wave energy. At the same time, relying on his professional background, insight from his personal abduction experiences and hundreds of cited scientific articles from peer-reviewed journals, the author demonstrates that the ultrasophisticated technical capabilities exhibited by the visitors to our planet are more than plausible. They represent a logical extrapolation of current human theoretical and applied science. Moreover, according to Rapuano, “ the powerful evidence of such technology which has existed for more than 60 years, especially with respect to incredibly advanced propulsion systems for interstellar space travel and implanted devices that are likely instruments of mind control, proves that the aliens are here. Potentially breakthrough scientific innovations underlying these highly advanced alien capabilities are revealed that make the book a de facto whistleblower report on the subject of UFO's and alien abduction. “ More importantly, this book, says Rapuano “ is a wake-up call to our species to finally accept the reality that we are now sharing our world with technologically superior non-human beings. This new reality must be addressed immediately. “ Reviews:“ A fantastic book that will make an impact on the field. ” – George Knapp. Mainstream American Scientist Bruce E. Rapuano Goes On the Record With His Own UFO Close Encounters and Alien Abduction Experiences In a Newly Released Book

Bruce Rapuano a B.A. degree from the University of Pennsylvania where he majored in Neurobiology and minored in Psychology, a Ph.D. in Neuropharmacology from the University of Connecticut and a J.D. from New York Law School. Dr. Rapuano has conducted independent biomedical research as a cell biologist at internationally recognized medical institutions including the Memorial Sloan-Kettering Cancer Center and the Hospital for Special Surgery, both located in New York City. Fred Roehl is a Curyung Tribal Counsel member From Dillingham Alaska And has had a not so pleasant encounter with the Alaskan Hairy Man (Bigfoot) now he collects people's reports in hopes to warn and help others about their unpredictable and often dangerous behaviors towards Mankind by sharing them on his YouTube channel.YouTube channelSubarctic Alaska Sasquatch subarcticalaskasasquatch.comBecome a supporter of this podcast: https://www.spreaker.com/podcast/night-dreams-talk-radio--2788432/support.

This edition of Airing Pain focuses on the treatment of pain, the importance of catering treatment to a person's individual genetic makeup, and why addressing the psychological dimensions of pain is crucial in treating it effectively.  The process of finding a medication or treatment that works for a person often involves a lot of trial and error, which can be a frustrating process for someone to go through. This process can be side-stepped through the use of personalised medicine, where information about a person's genetic makeup is used to tailor and optimise their treatment so it is as effective as possible. Although medication is oftentimes a vital part of treating pain, incorporating psychological treatment alongside medication can be hugely beneficial when it comes to making pain management better for those living with acute or chronic pain. Changing how someone thinks about pain can enhance their response to the physical components of the treatment they receive. Our contributors for this edition discuss the ways in which the treatment of pain can be made more effective for people by incorporating personalised medicine or psychological treatments into a person's care plan. Please leave us a review on this platform or give feedback via our Airing Pain survey. Contributors: Professor Tony Dickenson, Professor of Neuropharmacology at University College London. Dr. Beth Darnall, PhD, Professor of Anesthesiology, Perioperative and Pain Medicine at Stanford University School of Medicine. Director, Stanford Pain Relief Innovations Lab. Professor Irene Tracey, Vice Chancellor of the University of Oxford and a Professor of Anaesthetic Neuroscience in the Nuffield Department of Clinical Neurosciences. Read transcript Thanks: This edition of was made possible thanks to funding from the Guy Fawkes Charitable Trust and support from the British Pain Society. Time Stamps: 1:11 Paul introduces Professor Tony Dickenson,who he spoke to at the British Pain Society Annual Scientific Meeting 2022. 3:21 Professor Tony Dickenson discusses ‘precision medicine', ‘personalised medicine', and how looking at peoples' genetic makeup can help medical professionals treat pain more effectively.  14:21 Paul introduces Dr Beth Darnall, who he spoke to at the British Pain Society Annual Scientific Meeting 2023. 14:54 Dr Beth Darnall explains the psychological components of how people experience pain. 20:24 Paul introduces Professor Irene Tracy, who he spoke to at the British Pain Society Annual Scientific Meeting 2023.  20:57 Dr Irene Tracy discusses the work she's done on neuroimaging and how the human brain constructs the experience of pain.  23:22 Paul and Dr Tracy talk about what neuroimaging tells us about the multidimensional way the human brain reacts to pain. 26:06 Beginning of discussion about Empowered Relief, a psychology-based intervention that provides people with skills and tools to help manage their acute or chronic pain.  26:31 Dr Beth Darnall discusses the psychological side of treating pain and how empowered relief is used to help people manage their pain. 29:10 Dr Beth Darnall talks about the psychological tools people learn through Empowered Relief and how they help with pain management.    Additional Resources: Airing Pain 100: Glasgow Pain Education Sessions Empowered Relief  Pain Matters 80: What treatment really works 

We are joined by author and scientist Bruce E. Rapuano to discuss his book Dominion Lost: A Scientist's Own Alien Abduction Encounters. “ A fantastic book that will make an impact on the field. ” – George Knapp. Amazon book link: https://a.co/d/6KtySC3 Mainstream American Scientist Bruce E. Rapuano Goes On the Record With His Own UFO Close Encounters and Alien Abduction Experiences In a Newly Released Book New York, NY – February 5, 2024 - A newly published nonfiction book is the only first-person account to date of multiple UFO close encounters and alien abductions authored by a mainstream American scientist. In Dominion Lost: A Scientist's Own Alien Abduction Encounters recently discussed by the author with George Knapp on Coast to Coast AM, Dr. Bruce E. Rapuano goes on the record. Dr. Rapuano, who has multiple degrees in neuroscience, describes his UFO close encounters, including one in which he was abducted from a group of eight other witnesses, as well as experiences with advanced non-human beings and an unexplained nasal implant of specific structure all of which were recalled without regressive hypnosis. Also described are the author's interactions with short humanoid beings that reveal all the ways that that the aliens appear to control human behavior during the abduction process. The book further explains : · How the implants that are frequently reported by abductees work to analyze and influence the activity of the human brain. · Exactly how the “grey aliens” were genetically reengineered from our early hominin ancestors. · Precisely how the UFO propulsion system creates gravitational wave energy. At the same time, relying on his professional background, insight from his personal abduction experiences and hundreds of cited scientific articles from peer-reviewed journals, the author demonstrates that the ultrasophisticated technical capabilities exhibited by the visitors to our planet are more than plausible. They represent a logical extrapolation of current human theoretical and applied science. Moreover, according to Rapuano, “ the powerful evidence of such technology which has existed for more than 60 years, especially with respect to incredibly advanced propulsion systems for interstellar space travel and implanted devices that are likely instruments of mind control, proves that the aliens are here. Potentially breakthrough scientific innovations underlying these highly advanced alien capabilities are revealed that make the book a de facto whistleblower report on the subject of UFO's and alien abduction. “ More importantly, this book, says Rapuano “ is a wake-up call to our species to finally accept the reality that we are now sharing our world with technologically superior non-human beings. This new reality must be addressed immediately. “ Bruce E. Rapuano has a B.A. degree from the University of Pennsylvania where he majored in Neurobiology and minored in Psychology, a Ph.D. in Neuropharmacology from the University of Connecticut and a J.D. from New York Law School. He has conducted independent biomedical research as a cell biologist at internationally recognized medical institutions. *************************************************************** You can email the hosts with your UFO/UAP and Paranormal stories at: mi.ufo.podcast@gmail.com Help support the show with the links below: Join this channel to get access to perks: https://www.youtube.com/channel/UCjUTzsRX5rBq9_r7_YtaEJg/join You can now purchase our Merch on the "STORE" TAB in the channel description All Our Links Including Our MERCH Store: https://linktr.ee/mi.ufo.podcast Paypal: Donate via paypal: https://paypal.me/miufo Become a Patreon supporter and get a show shoutout for as long as you're a member! Become a Patreon at: https://www.patreon.com/miufospep --- Send in a voice message: https://podcasters.spotify.com/pod/show/michiganufos/message Support this podcast: https://podcasters.spotify.com/pod/show/michiganufos/support

Coming 10 April: This edition of Airing Pain focuses on the treatment of pain, the importance of catering treatment to a person's individual genetic makeup, and why addressing the psychological dimensions of pain is crucial in treating it effectively.   Our contributors for this edition discuss the ways in which the treatment of pain can be made more effective for people by incorporating personalised medicine or psychological treatments into a person's care plan.  This edition will be funded by the Guy Fawkes Charitable Trust and was created with support from the British Pain Society. Contributors:  Professor Tony Dickenson, Professor of Neuropharmacology at University College London  Dr. Beth Darnall, PhD, Professor of Anesthesiology, Perioperative and Pain Medicine at Stanford University School of Medicine. Director, Stanford Pain Relief Innovations Lab. Professor Irene Tracey, Vice Chancellor of the University of Oxford and a Professor of Anaesthetic Neuroscience in the Nuffield Department of Clinical Neurosciences. 

This week I'm reading from Bruce Rapuano's book 'Dominion Lost: A Scientist's Own Alien Abduction Encounters'.This bombshell nonfiction book, recently discussed by the author with George Knapp on Coast to Coast AM, is the only first-person account to date of UFO alien abductions authored by a mainstream American scientist. The author, who has multiple degrees in neuroscience, goes on the record regarding his incredible and fascinating experiences with UFO close encounters, including a very close encounter during which he was abducted from a group of eight other witnesses, interactions with alien beings and an unexplained nasal implant of specific structure all of which were recalled without regressive hypnosis. Also riveting are the author's experiences with short humanoid beings that are described in captivating detail to reveal all the ways that aliens control human behavior during the abduction process.Even more amazing is the fact that this book is the first to explain :how the implants that are frequently reported by abductees work to analyze and influence the activity of the human brain.exactly how the “grey aliens” were genetically reengineered from our early hominin ancestors.precisely how the UFO propulsion system creates gravitational wave energy.At the same time, relying on his professional background, insight from his personal abduction experiences and numerous cited scientific articles from peer-reviewed journals, the author demonstrates that the ultrasophisticated technical capabilities exhibited by the alien visitors to our planet are more than plausible. They represent a logical extrapolation of current human theoretical and applied science.Moreover, the powerful evidence of such technology which has existed for more than 60 years, especially with respect to incredibly advanced propulsion systems for interstellar space travel and implanted devices that are likely instruments of mind control, proves that the aliens are here. Potentially breakthrough scientific innovations underlying these highly advanced alien capabilities are revealed and clearly explained, making the book a de facto whistleblower report on the subject of UFO's and alien abduction. More importantly, this book is a wake-up call to our species to finally accept the reality that we are now sharing our world with technologically superior alien beings. This new reality must be addressed immediately.BioBruce Rapuano a B.A. degree from the University of Pennsylvania where he majored in Neurobiology and minored in Psychology, a Ph.D. in Neuropharmacology from the University of Connecticut and a J.D. from New York Law School. Dr. Rapuano has conducted independent biomedical research as a cell biologist at internationally recognized medical institutions including the Memorial Sloan-Kettering Cancer Center and the Hospital for Special Surgery, both located in New York City. He has authored or coauthored thirty scientific articles in peer-reviewed medical journals. He has published articles on topics such as the role of membrane phospholipids in nerve function, the skeletal effects of cancer metastases, metabolic bone diseases and the coordinate surface electrical and biological properties of titanium alloy implant materials. Dr. Rapuano has also worked concurrently as a medical research scientist and Associate Radiation Safety Officer at the Hospital for Special Surgery. Amazon link https://tinyurl.com/2wtk39fehttps://www.pastliveshypnosis.co.uk/https://www.patreon.com/alienufopodcast

This week I'm talking to Bruce Rapuano about his book 'Dominion Lost: A Scientist's Own Alien Abduction Encounters'.This bombshell nonfiction book, recently discussed by the author with George Knapp on Coast to Coast AM, is the only first-person account to date of UFO alien abductions authored by a mainstream American scientist. The author, who has multiple degrees in neuroscience, goes on the record regarding his incredible and fascinating experiences with UFO close encounters, including a very close encounter during which he was abducted from a group of eight other witnesses, interactions with alien beings and an unexplained nasal implant of specific structure all of which were recalled without regressive hypnosis. Also riveting are the author's experiences with short humanoid beings that are described in captivating detail to reveal all the ways that aliens control human behavior during the abduction process.Even more amazing is the fact that this book is the first to explain :how the implants that are frequently reported by abductees work to analyze and influence the activity of the human brain.exactly how the “grey aliens” were genetically reengineered from our early hominin ancestors.precisely how the UFO propulsion system creates gravitational wave energy.At the same time, relying on his professional background, insight from his personal abduction experiences and numerous cited scientific articles from peer-reviewed journals, the author demonstrates that the ultrasophisticated technical capabilities exhibited by the alien visitors to our planet are more than plausible. They represent a logical extrapolation of current human theoretical and applied science.Moreover, the powerful evidence of such technology which has existed for more than 60 years, especially with respect to incredibly advanced propulsion systems for interstellar space travel and implanted devices that are likely instruments of mind control, proves that the aliens are here. Potentially breakthrough scientific innovations underlying these highly advanced alien capabilities are revealed and clearly explained, making the book a de facto whistleblower report on the subject of UFO's and alien abduction. More importantly, this book is a wake-up call to our species to finally accept the reality that we are now sharing our world with technologically superior alien beings. This new reality must be addressed immediately.BioBruce Rapuano a B.A. degree from the University of Pennsylvania where he majored in Neurobiology and minored in Psychology, a Ph.D. in Neuropharmacology from the University of Connecticut and a J.D. from New York Law School. Dr. Rapuano has conducted independent biomedical research as a cell biologist at internationally recognized medical institutions including the Memorial Sloan-Kettering Cancer Center and the Hospital for Special Surgery, both located in New York City. He has authored or coauthored thirty scientific articles in peer-reviewed medical journals. He has published articles on topics such as the role of membrane phospholipids in nerve function, the skeletal effects of cancer metastases, metabolic bone diseases and the coordinate surface electrical and biological properties of titanium alloy implant materials. Dr. Rapuano has also worked concurrently as a medical research scientist and Associate Radiation Safety Officer at the Hospital for Special Surgery. Amazon link https://tinyurl.com/2wtk39fehttps://www.pastliveshypnosis.co.uk/https://www.patreon.com/alienufopodcast

 50% of the population have Magnesium deficiency.I had quite often muscle cramps and with Magnesium intake, it stops… Afterward, I ate all kinds of seaweed, drank hot cacao (out of natural, unprocessed cacao with water), flaxseed, Brazil nuts; ate very much green salad, … I didn't need any Magnesium supplements… This works… Still, I decided I take just a little bit of Magnesium supplement. A Magnesium deficiency can easily kill us… Magnesium is in so many processes involved, that a deficiency can trigger many symptoms. Without proper pro-biotic, we cannot get the Magnesium out of the food. Take your pro-biotic or eat fermented food every day. If you do have a couple of these 8 Symptoms you do have Magnesium deficiency.1. Muscle crampsMagnesium directly interacts with your muscle tissue through a process called ion transportation. When magnesium contacts your cell membranes, it bonds with specific receptor sites that open up the cell membrane and allow other mineral ions to enter, such as calcium and potassium. Worst case Heart attack. 2. SleeplessnessMagnesium binds to gamma-aminobutyric acid (GABA) receptors and activates them. GABA is the neurotransmitter responsible for quieting down nerve activity.A lack of magnesium can result in low GABA levels, and when GABA is low, your brain gets stuck in the “on” position and it becomes impossible to relax. 3. Anxiety/StressA 2012 report, published in the Journal of Neuropharmacology, found that magnesium deficiency caused an increase in the production of cortisol in the brains of the mice, specifically by activating the paraventricular hypothalamic nucleus, a part of the brain that controls responses to stress and anxiety.4. OsteoporosisIt's not well known that magnesium is necessary to convert vitamin D into its active form so that it can turn on calcium absorption.Magnesium stimulates the hormone calcitonin, which helps to preserve bone structure by drawing calcium out of the blood and soft tissues back into the bones. This action helps lower the likelihood of osteoporosis.5. Muscle WeaknessA decrease in intracellular magnesium, caused by magnesium deficiency, releases the magnesium-mediated inhibition of ROMK channels and increases potassium secretion.6. High Blood PressureMagnesium plays a critical role in BP regulation as it's been shown to stimulate prostacyclin and nitric oxide formation.7. Constipation The laxative effect of magnesium appears to come through two different mechanisms.Muscle Relaxation: Magnesium relaxes the muscles in the intestines, which can help to establish a smoother flow as the stool passes through the bowels.Stool Softener: Magnesium draws water into the intestines, working as an osmotic laxative. This increase in water stimulates bowel motility - it also softens and increases the size of the stool, triggering a bowel movement and helping to make stools easier to pass.8. Low Energy Gluconeogenesis increases on keto, demanding more ATP.ATP (adenosine triphosphate), the main source of energy in cells, must be bound to a magnesium ion in order to be biologically active - what is called ATP is often actually Mg-ATP.In other words, magnesium is required in the reactions that create ATP energy in the cellsWithout magnesium, you literally won't have energy on a cellular level - this shows up as fatigue, low energy, lack of drive, and other problems.There exist many supplements, and most of them have negative side effects or the body cannot process them. The best is Magnesium glycinate, has no side effects, is easy to digest, and is best for relaxation… The next best is Magnesium citrate, which has side effects… And all the other Magnesium supplements are good for the garbage. Recommend are, that we get every day around 400mg of Magnesium in our blood. This means we eat a lot of green leaves and other food as I have described… We supplement only 200mg. My Video: Do you get enough Magnesium? https://youtu.be/H4geyS60nt8My Audio: https://divinesuccess.net/wp-content/uploads/2021/Podcast2/Do-you-get-enough-Magnesium.mp3

Over the past few years, the health and wellness space has been flooded with the concept of the "gut microbiome," or the ecosystem of microorganisms in our stomachs. Probiotics, which have become prominent on social media, are said to strengthen this bacterial community and can result in benefits like improved nutrient absorption, skin inflammation, and even mental acuity. However, this connection of the gut to the mental sphere has actually been shown in research as the "gut-brain axis" (GBA). In fact, according to a 2015 journal from the Annals of Gastroenterology, a bidirectional relationship between our gut and our brain has been shown to influence our responses to anxiety, stress, and even functions of memory through interactions with the central nervous system.We are joined today by behavioral neuroscientist, toxicologist, neuropharmacologist, and international fashion model Dr. Aya Osman. She received her BSc in Biomedical Sciences with Honors from the University of London, MSc in Toxicology focusing on the role of adenosine and glutamate receptors in cocaine addiction from the University of Surrey, and PhD in Toxicology and Neuropharmacology from the University of Surrey, where she investigated the development of brain opioid and oxytocin receptor systems in response to early life dietary manipulation. She then worked as a Toxicologist at the Centre for Radiation, Chemical, and Environmental Hazards for the governmental body Public Health England. Dr. Osman completed her postdoctoral research fellowship at the Friedman Brain Institute and the Seaver Autism Center for Research and Treatment at Icahn School of Medicine at Mount Sinai, where she now serves as an Assistant Professor, focusing on the role of gut microbiome changes in brain development and the pathophysiology of neuropsychiatric disorders.Livestream Air Date: April 25, 2023Follow Aya Osman, PhD: InstagramFollow Friends of Franz Podcast: Website, Instagram, FacebookFollow Christian Franz Bulacan (Host): Instagram, YouTubeThankful to the season's brand partners: Covry, House of M Beauty, Nguyen Coffee Supply, V Coterie, Skin By Anthos, Halmi, By Dr Mom, LOUPN, Baisun Candle Co., RĒJINS, Twrl Milk Tea, 1587 Sneakers

No episódio 28 do Lupus in Fabula: Pele de Cordeiro, Rodrigo Grola, Marcos Keller e Cussa Mitre e Paulo Gaio falam sobre as questões tecnicas e biológicas envolvendo o uso do Ayahuaska.   LiF: Pele de Cordeiro, uma produção HodStudios   Apresentação: Cussa Mitre, Marcos Keller e Rodrigo Grola ………………………………………………………………………………………… Alguns trabalhos envolvendo Ayahuaska 5-Hydroxytryptamine Receptor Subtypes and their Modulators with Therapeutic Potentials https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318857/#:~:text=5%2DHT%20is%20autacoids%20as,numerous%20behavioral%20and%20physiological%20functions.) Behavioural and neurotoxic effects of ayahuasca infusion (Banisteriopsis caapi and Psychotria viridis) in female Wistar rat https://pubmed.ncbi.nlm.nih.gov/26049017/ Carbonaro, Theresa M and Michael B Gatch. “Neuropharmacology of N,N-dimethyltryptamine” Brain research bulletin vol. 126,Pt 1 (2016): 74-88. Gardner, D., Riet-Correa, F., Lemos, D., Welch, K., Pfister, J., Panter, K., 2014. Teratogenic effects of Mimosa tenuiflora in a rat model and possible role of N-methyl- and N,N- dimethyltryptamine. J. Agric. Food Chem. 62 (30), 7398–7401. Lindsay P. Cameron and David E. Olson Dark Classics in Chemical Neuroscience: N,N-Dimethyltryptamine (DMT) – ACS Chemical Neuroscience 2018 9 (10), 2344-2357 https://www.nucleodoconhecimento.com.br/saude/ayahuasca-na-doenca-mental - O POTENCIAL TERAPÊUTICO DA AYAHUASCA NA DOENÇA MENTAL - TELES, Thábata Barros de Sá Development and challenges in the discovery of 5-HT1A and 5-HT7 receptor ligands https://www.sciencedirect.com/science/article/pii/S0045206822006605#b0120 Ayahuasca: Psychological and Physiologic Effects, Pharmacology and Potential Uses in Addiction and Mental Illness https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343205/#:~:text=%5B69%5D%20reported%20that%20ayahuasca%20produced,hemisphere%20(areas%20involved%20in%20somatic Serotonin 5-HT2A and 5-HT2C Receptors as Potential Targets for Modulation of Psychostimulant Use and Dependence http://dx.doi.org/10.2174/156802606778522131   ………………………………………………………………………………………… Apoie o Lupus in Fabula! https://www.catarse.me/lifhod ………………………………………………………………………………………… Linktree LiF: https://linktr.ee/lifhod ………………………………………………………………………………………… Todas as opiniões e comentários feitos pelos convidados do programa são de inteira responsabilidade dos mesmos. As opiniões emitidas não exprimem necessariamente o ponto de vista de nenhum dos membros ou da HodStudio. … Apoie-nos em Catarse.me/lifhod e assista ao vivo as gravações deste programa! Quer aprender tarot? Acesse o site do Mitos Modernos! Quer aprender runas? Acesse o site do Runologia!   Siga-nos em nossas redes sociais! Twitter: https://twitter.com/lifhod Instagram: https://instagram.com/lifhod Facebook: https://www.facebook.com/lifhod   Assine nosso canal no Youtube! YouTube.com/lupusinfabula

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Madhukar H. Trivedi, MD The brain is constantly changing as a result of experience, stress, emotional processing, learning, and memory.1 And neuroplasticity adds another layer to these approaches by focusing on what's actually changing in the brain.2 Tune in with Dr. Charles Turck as he speaks with Dr. Madhukar Trivedi, Founding Director of the Center for Depression Research and Clinical Care and Chief of the Division of Mood Disorders at the University of Texas Southwestern Medical Center in Dallas, Texas. Sanacora G, Treccani G, Popoli M. Towards a glutamate hypothesis of depression: an emerging frontier of neuropsychopharmacology for mood disorders. Neuropharmacology. 2012;62(1):63-77. Mateos-Aparicio P, Rodriguez-Moreno A. The impact of studying brain plasticity. Front Cell Neurosci. 2019;13:66. August 2023 US.UNB.X.23.00081

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Madhukar H. Trivedi, MD The brain is constantly changing as a result of experience, stress, emotional processing, learning, and memory.1 And neuroplasticity adds another layer to these approaches by focusing on what's actually changing in the brain.2 Tune in with Dr. Charles Turck as he speaks with Dr. Madhukar Trivedi, Founding Director of the Center for Depression Research and Clinical Care and Chief of the Division of Mood Disorders at the University of Texas Southwestern Medical Center in Dallas, Texas. Sanacora G, Treccani G, Popoli M. Towards a glutamate hypothesis of depression: an emerging frontier of neuropsychopharmacology for mood disorders. Neuropharmacology. 2012;62(1):63-77. Mateos-Aparicio P, Rodriguez-Moreno A. The impact of studying brain plasticity. Front Cell Neurosci. 2019;13:66. August 2023 US.UNB.X.23.00081

Have you ever want to change your mind? Well what if you changed your brain instead? In this new episode Steven sits down with neuroscientist, executive advisor and author, Dr Tara Swart Bieber.  Dr Swart, has a PHD in Neuropharmacology and a past successful career medical doctor as a psychiatrist. From there she transferred into becoming a top level leadership coach, specialising in improving mental resilience in CEO's and helping them to operate at peak brain performance. Her clients include leaders of FTSE100, Fortune 500 and Magic Circle firms. She is a Senior Lecturer at MIT Sloan, and the author of the bestselling book, ‘The Source'.  In this conversation Tara and Steven discuss topics, such as: How emotions are contagious Neuroscience tricks for love and connection How Tara uses neuroscience to help leaders  Using neuroscience to handle stress How stress can make you fat  The way that exercise can combat stress How the brain cleans itself  The chemical nature of love How to improve relationships using neuroscience Why your gut instinct is real Why the world needs a spiritual revolution The impact of porn on the brain  How your friendship group impacts your brain and health The ways to physically change your brain How trauma can be inherited  How trauma changes your genes  The ways that you can train and strengthen your brain How exercise can change the brain The science of the law of attraction and manifestation Changing the voice in your head How your thoughts can stop you ageing  You can purchase Tara's book, ‘The Source', here: https://bit.ly/3Rs1m8b  Follow Tara: Instagram: https://bit.ly/48hJ1k2  Twitter: https://bit.ly/46gqYZI  Watch the episodes on Youtube - https://g2ul0.app.link/3kxINCANKsb My new book! 'The 33 Laws Of Business & Life' is out now: https://smarturl.it/DOACbook Follow me: Instagram: http://bit.ly/3nIkGAZ Twitter: http://bit.ly/3ztHuHm Linkedin: https://bit.ly/41Fl95Q Telegram: http://bit.ly/3nJYxST Sponsors: https://www.eightsleep.com/uk/steven/ CODE: STEVEN (save $150 on the Pod Cover) Huel: https://g2ul0.app.link/G4RjcdKNKsb Learn more about your ad choices. Visit megaphone.fm/adchoices

Ooooh, y'all, do we have a treat for you in this episode! On today's special episode, the tables are turned on Dr. Jasmine for an interview she did with fellow badass career coach Cassie Spencer on her podcast Happenstance. You'll hear all about Dr. Jasmine's crazy journey of quitting her job and starting this business.But the key to her success? The support of her community. Her community is what ultimately led her to create The Professional Quitters, her group coaching program and community, which is all about helping you create the career you want your way. And, of course…make bank! So today, we're celebrating community and Cassie and the first anniversary of her podcast, Happenstance!And, of course, you'll get the DL on how Dr. Jasmine created this amazing business and community for women of color professionals. ----------------------In today's episode, we cover the following:The best job Dr. Jasmine has ever hadHow she dove into career coachingHer backstory: from growing up in The Projects to getting a Ph.D. in Neuropharmacology to following her true desiresAdvice for making the giant leaps you wanna takeHer surprises and challenges since starting her businessMoving to MiamiA true "happenstance" momentValuable career advice-----------------------Resources mentioned:Ready to be a proud quitter? Join my exclusive group coaching program: The Professional Quitters, and start making up to 50% more!-----------------------Guest info:To hang out with Cassie, follow her on LinkedIn at Cassie Spencer and Instagram at @CareerCoachCassie and @HappenstanceThePodcast. If you'd like to work with Cassie, you can view her offerings at her website, CareerCoachCassie.Squarespace.com. -----------------------Let's connect!Instagram: @JasmineEscaleraCoaching & @HerNextCareerMove_LinkedIn: Jasmine Escalera, Ph.DAre you ready to support women of color to flourish in the workplace and gain respect and credit? Book Dr. Jasmine for your next event! www.jasmineescalera.com

Welcome to the XR Magazine podcast! In this episode, we are thrilled to have Valentino Megale, an exceptional entrepreneur and expert in the fields of XR (Extended Reality) and Digital Health. With a Ph.D. in Neuropharmacology, Valentino brings a unique perspective to the intersection of technology and healthcare. Valentino is the CEO of Softcare Studios Srls, a groundbreaking digital health startup that specializes in developing virtual reality solutions for drug-free stress and pain management in medical settings. Through his leadership, Softcare Studios is revolutionizing patient care by harnessing the power of XR to enhance well-being and improve treatment outcomes. But Valentino's influence doesn't stop there. As an advisor to the global initiative XRSI (Extended Reality Safety Initiative), he lends his expertise to medical XR, digital safety, privacy in the metaverse, and child safety in virtual worlds. His commitment to ensuring ethical practices and safeguarding users' well-being is commendable. In addition to his entrepreneurial ventures, Valentino also serves as a professor at the prestigious Rome Business School, where he shares his wealth of knowledge and inspires the next generation of business leaders. Join us as we dive into an engaging conversation with Valentino Megale, exploring the transformative potential of XR in healthcare, the importance of digital safety, and the future of virtual worlds. Whether you're a tech enthusiast, healthcare professional, or simply curious about the intersection of technology and well-being, this episode is sure to leave you inspired and informed. In this episode, you'll learn: The transformative potential of Extended Reality (XR) in the realm of Digital Health. The importance of digital safety and privacy in the metaverse. The challenges and potential solutions for ensuring the well-being of children in virtual environments. The potential applications of XR beyond stress and pain management, envision a world where virtual reality is integrated into various aspects of patient care, rehabilitation, and mental health support. Please let me know if you have any questions about this episode or what guests you would like me to bring next! Thanks for your support!

In this behind-the-scenes interview we talk with Dr. Maria T Rivera-Garcia about her research investigating the effects of CBD-rich whole plant extract vapor on pain and opioid reward seeking behavior in female rats in a study titled, "High-CBD Cannabis Vapor Attenuates Opioid Reward and Partially Modulates Nociception in Female Rats". While on the surface this may seem like a simple study about how CBD influences opioid use - there is actually a lot more going on here. First of all this study utilized female rodents, which is very uncommon. The vast majority of preclinical rodent research uses male rodents almost exclusively due to reasons we unpack during the episode. This has led to a gross under-representation of sex differences in biomedical research. Second, Maria and colleagues decided to utilize the vapor of whole plant CBD-rich Cannabis extract rather than using CBD isolate that is often diluted and injected, ultimately leading to results that do not accurately reflect real-world situations. Together, these two decisions point to a common theme that is woven into this research study - scientists need to focus on doing research that better represents the real world. The results from this study are fascinating, so get your notebook ready and let's dive in! Link to the study: https://www.sciencedirect.com/science/article/pii/S2772392522000451 About Maria: Maria Teresa Rivera-Garcia has a major in psychology and a minor in neuroscience from the National Autonomous University of Mexico, where she started defining her academic interests towards the study of neurobiological mechanisms of addiction. After undergrad, Maria did a Master and a PhD in Neuropharmacology and Experimental Therapeutics, her research focused on the neurochemical effects of solvent inhalation and its relation with the development of psychosis. Maria moved to the US in 2016 to pursue her postdoctoral training in the Oregon and Health and Science University, studying sex and age differences in dopaminergic function and how this is related to psychiatric illnesses, including addiction. In 2020, Maria joined Legacy Research Institute to complete her second postdoctoral stay under the guidance of Dr. Adie R. Wilson-Poe, where she studied the pharmacological interaction between opioids and cannabinoids in pain-oriented models. Recently, Maria got accredited as Qualified Mental Health Provider and became a member of the Cascadia Health clinicians team, currently providing services within the Child and Family Program. #CannabisEducation #CBD #CBDOil #WholePlantExtract #WholePlant #FullSpectrum #BroadSpectrum #Hemp #HempExtract #MedicalCannabis #Addiction #MentalHealth #Opioids #CuriousAboutCannabis

In today's episode, I chat with Valentino Megale, the Rome-based CEO & Co-Founder of Softcare Studios, a digital health startup developing XR solutions in healthcare and well-being, with a special focus on pain and stress management in patients undergoing invasive medical procedures, and optimization of healthcare interventions.Selected as the best e-health startup in Europe by the European Commission in 2018, Softcare Studios' track record includes commercial partnerships with leading MedTech and pharma companies like Merck, Roche, Novartis and BD, and collaborations with a growing network of hospitals, medical specialists and research partners such as the Politecnico and CNR in Milano.Together we discussed the potential for XR to transform healthcare as we know it, the barriers to adoption, from both patients & healthcare professionals, and how virtual reality, in particular, can generate value today & into the future. If you're a return listener to this podcast, you know how passionate I am about the use cases of VR in large enterprise. Though its in industries such as healthcare that will likely lead the way. Demographically-speaking, we're at an inflection point in North America, Europe & Asia-Pacific. Our populations are aging & we need innovative solutions to ensure citizens receive a standard of care necessary to live long, happy lives. It gives me confidence speaking with innovators such as Valentino. And I really enjoyed our conversation. I hope you do, as well. Valentino MegaleStartup founder, currently CEO of Softcare Studios, a digital health startup developing virtual reality solutions for pain and stress management of patients undergoing medical treatments. A scientist by training, with a Ph.D. in Neuropharmacology. He is also an advisor on the topics of digital safety and privacy in the metaverse (with a special focus on child safety and medical XR) as a member of the Extended Reality Safety Initiative (XRSI) non-profit organization. Startup mentor, lecturer and author on the topics of emerging tech, healthcare, and social impact.WebsiteLinkedInThinking Inside the BoxConstraints drive innovation. We tackle the most complex issues related to work & culture. And if you enjoy the work we're doing here, consider giving us a 5-star rating, leaving a comment & subscribing. It ensures you get updated whenever we release new content & really helps amplify our message.LinkedInInstagramTwitterWebsiteApple PodcastsGoogle PodcastsSpotifyStitcherPocket CastMatt BurnsMatt Burns is an award-winning executive, social entrepreneur and speaker. He believes in the power of community, simplicity & technology.LinkedInTwitter

In this episode, we speak to Gitte Moos Knudsen, Chair of the Human Brain Project Science and Infrastructure Advisory Board. She spoke about her research on how drugs influence the brain, her role in the Human Brain Project, and what advice she would give to her younger self.Knudsen is also Clinical Professor and Chief Physician at the Department of Clinical Medicine, Neurology, Psychiatry and Sensory Sciences, at Copenhagen University Hospital.To learn more about the Human Brain Project, please visit www.humanbrainproject.eu

According to the CDC, illegal fentanyl is the main driver of the recent increase in opioid deaths in the United States. What is the history of fentanyl, its uses, and the role in addiction and in the opioid epidemic? Join us on our podcast episode “The Rise of Fentanyl” where we'll be discussing these points and more.

With America's Opioid Epidemic in full swing, it is time that we look into the options that we have available to us. This podcast will dive into an alternative medication that has proven to be effective in helping individuals get and stay off opioids with dramatic success: Ibogaine.

In this episode, we discuss the drug cannabis and the social and legal issues surrounding it. Hopefully this will bring some new insight to the ongoing discussion as to whether marijuana should be used medically, and whether the stigma surrounding its use be abandoned or not. Let's get started!

MDMA has shown to be a promising drug for treating individuals with chronic Post Traumatic Stress Disorder (PTSD) when used as an adjunct to psychotherapy. Tune in to learn more about how this drug can help treat those with PTSD.

Psilocybin has been posited as a groundbreaking, yet controversial, treatment for severe depression. But what does the research say about it? In this episode, we discuss the history, mechanisms, legal standing, and efficacy of psilocybin in a therapeutic setting.

Andrea De Souza, is Associate Vice President, Research Data Sciences and Engineering, at Eli Lilly & Company (https://www.lilly.com/) where over the past three years her work has focused around empowering the Lilly Research Laboratories (LRL) organization with greater computational, analytics-intense experimentation to raise the innovation of their scientists. A former neuroscience researcher, Andrea's portfolio career has included leadership assignments at the intersection of science, technology and business development. She has built and led informatics and scientific teams across the entire pharmaceutical value chain. Most recently, Andrea focused on building the Pharma Artificial Intelligence market at NVIDIA. Through this experience she has traveled the world advising bio-pharmaceutical clients, academics, research institutes, and startups in the potential of machine learning and artificial intelligence across every discipline of the industry. Prior to her role at NVIDIA, Andrea held leadership positions at the Broad Institute of Harvard and MIT, Amgen, and Roche. In her current role as Associate Vice President at Lilly, Andrea leads four organizations: the High-Performance Computing Team, the Data Engineering team, the AI/ML team and the Translational Informatics team for LRL. Additionally, Andrea serves as a strategic advisor for the U.S. National Institutes of Health (NIH) for The Human BioMolecular Atlas Program (HubMap) Advisory Team. Andrea has a B.S. in Animal Physiology from UC Davis, a Master's in Health Administration from University of San Francisco, and an MBA from MIT Sloan. Through her broad research efforts, Andrea has publications in journals as diverse as the Journal of Computer-Aided Molecular Design, Bio-organic & Medicinal Chemistry Letters, and Neuropharmacology. Her leadership has gained her international recognition as a leader in Big Data, Artificial Intelligence and Data Sciences.

Methamphetamine abuse affects over twenty million individuals in the US, with users criminalized instead of seen as individuals struggling with a serious illness. Join us as we discuss how meth abuse affects an individual's brain and life, and what we can do as a country to help these individuals heal post-drug abuse.

Welcome to the Head to Heal Podcast Heads up! I am not a medical doctor and you should always seek help from a physician before beginning any new health regime. On this weeks Episode Jiordana talks all about Microdosing and and how to use it with various mental health disorders and to make positive changes in your brain. We cover: What Microdosing is How it works Why mental health disorders are resistant to change When to use microdosing (and when to not) Info on Microdosing course Hit the LIKE & SUBSCRIBE button! This keeps the information free and available to everyone. Don't forget to share this episode with someone who you feel can value from it! Links: Book a free consultation! FREE LIVE Microdosing Q&A “Daily Dose” Mind-Full Microdosing Course Website: www.themindfullclinic.com Instagram: @themindfullclinic Email: jiordana@themindfullclinic.com References: Argento, E., Capler, R., Thomas, G., Lucas, P., & Tupper, K. W. (2019b). Exploring ayahuasca‐assisted therapy for addiction: A qualitative analysis of preliminary findings among an indigenous community in Canada. Drug and Alcohol Review, 38(7), 781–789. https://doi.org/10.1111/dar.12985 Carhart-Harris, R. L., Kaelen, M., Bolstridge, M., Williams, T. M., Williams, L. T., Underwood, R., ... Nutt, D. J. (2016). The paradoxical psychological effects of lysergic acid diethylamide (LSD). Psychological Medicine, 46(7), 1379–1390. https://doi.org/10.1017/s0033291715002901 Dos Santos, R. G., Osório, F. L., Crippa, J. A., Riba, J., Zuardi, A. W., & Hallak, J. E. (2016). Antidepressive, anxiolytic, and antiaddictive effects of ayahuasca, psilocybin and lysergic acid diethylamide (LSD): a systematic review of clinical trials published in the last 25 years. Therapeutic Advances in Psychopharmacology, 6(3), 193–213. https://doi.org/10.1177/204512531663800 Ezquerra-Romano, I., Lawn, W., Krupitsky, E., & Morgan, C. J. A. (2018). Ketamine for the treatment of addiction: Evidence and potential mechanisms. Neuropharmacology, 142, 72–82. https://doi.org/10.1016/j.neuropharm.2018.01.017

Is binge eating an addictive disorder or an impulse-control disorder? In this episode, Dr. Phelps summarizes the evidence of efficacy of several medications for binge eating disorder. He also discusses the psychopathology and neuropharmacology of binge eating disorder.  Faculty: Jim Phelps, M.D.  Hosts: Jessica Diaz, M.D.; Flavio Guzman, M.D. Learn more about Premium Membership here Earn 0.5 CMEs: Quick Take Vol. 33 Prospects for New Drugs To Treat Binge Eating Disorder: Insights From Psychopathology and Neuropharmacology

Join Newsletter get Free Gift:https://mailchi.mp/5e4f8e9f90e7/untitled-page**Support the Podcast**SuperCast: https://thingsyoushouldknow.supercast.comPatreon:  https://www.patreon.com/thingsyoushouldknowpodcast**Social Media***Facebook: https://www.facebook.com/groups/879254746173653Instagram: https://www.instagram.com/thing.syoushouldknow/**Fitness, Yoga and Mindfulness**Alo Moves: https://www.talkable.com/x/rSpBAv**Free 30 day trial / Yoga, Mindfulness and Meditation-----------------------------------------------------------WAYS TO CREATE ADDITIONAL REVENUETOP 3 OFFERS1 - https://c476dlqztiy6vh147kdz0y5m41.hop.clickbank.net/?cbpage=dirsp12 - https://7c81ffn0ja22uga1lqm33ma1jt.hop.clickbank.net/3 - https://797acut2siy6wj81r2xauxe39j.hop.clickbank.net/-------------------------------------------------------------What Happens to Your Body When You Drink a Glass of Wine Every NightSure, you might have experienced the anecdotal effects of this when you wind down with a glass of wine at the end of a long day. But there is actually some research behind wine's stress-lowering effects. A compound in red wine, called resveratrol, is responsible for a lot of wine's anti-inflammatory benefits. Research from 2019 in the journal Neuropharmacology found that resveratrol might have anti-stress effects by blocking enzymes in the brain that lead to depression- and anxiety-like behaviors. Another review of studies found that moderate wine consumption (one glass a day for females and two glasses a day for males) was associated with a 32% lower risk of depression. Support the show (https://www.patreon.com/thingsyoushouldknowpodcast)

In this episode, Drs. Suzanne Tinsley, PhD, PT and Janine Hatch, PT, DPT, MS come onto the HET Podcast to discuss the area of medical marijuana and help us understand how this drug interacts and affects patient outcomes. Biography: Dr. Hatch holds a BS degree in PT from New York University, and a Master's and Doctor of PT degrees from MGH-IHP with concentrations in balance disorders in the elderly and clinical management of vestibular disorders. Her thesis research at MGH-IP garnered the APTA Dorothy Briggs Award in 2002. She earned her Geriatric Clinical Specialist Certification in 2009 and recertified in 2019, and became a Certified Vestibular Therapist through Emory University in 2016. Dr. Hatch has 26 years of teaching experience in both entry-level and post professional doctoral physical therapy programs. She is currently the Associate Director of the Transitional Doctor of Physical Therapy program at Shenandoah University, with teaching responsibilities in Professionalism in Physical Therapy and the Capstone courses Emerging Clinical Practice. In her 31 years of clinical practice, she has had extensive experience managing adult clients with musculoskeletal conditions, balance and mobility disorders, and vestibular dysfunction across the spectrum of clinical settings, and is currently practicing at the Carolton Chronic and Convalescent Hospital. Dr. Hatch has authored a number of publications on balance and vestibular dysfunction, has presented at both a regional and national level, and is a reviewer for several peer-reviewed journals, including the Journal of Geriatric Physical Therapy and the American Journal for Physical Medicine and Rehabilitation. Dr. Tinsley received her Master's in Physical Therapy from Texas Woman's University in 1986 and her PhD in Neuropharmacology from Louisiana State University Health Sciences Center-Shreveport in 1999. She is an Associate Professor in the Department of Rehabilitation Sciences at Louisiana State University Health Sciences Center-Shreveport. Dr. Tinsley teaches medical pharmacology in the School of Allied Health Professions, School of Graduate Studies and School of Medicine. Dr. Tinsley is an APTA Board Certified Neurologic Physical Therapist and has presented nationally at APTA conferences as well as numerous continuing education seminars on the topic of pharmacology and rehabilitation. She currently serves as Chair of the Stroke SIG, Neurology Section, APTA. She has an active clinical practice in the area of neurological rehabilitation as well as an active clinical research agenda.

Guest: Valentino Megale. Valentino is a tech entrepreneur focused on digital health and mental well-being, TEDx speaker, and writer. He's a biologist, Ph.D. in Neuropharmacology, with International academic research experience in pharmacology, organic chemistry, and molecular biology in the fields of oncology and neuronal metabolism. Since 2017, he's been the CEO and co-founder of Softcare Studios, a digital health startup specialized in developing virtual reality solutions for stress management and therapy education in patients undergoing medical treatments. He's also a regular contributor to online magazines on the topics of emerging tech, healthcare, and startup ecosystems. We have an extremely interesting conversation about how immersive technologies will change the game in the future of healthcare and how to leverage the power of our minds to improve our lives.

Guest: Valentino Megale. Valentino is a tech entrepreneur focused on digital health and mental well-being, TEDx speaker, and writer. He's a biologist, Ph.D. in Neuropharmacology, with International academic research experience in pharmacology, organic chemistry, and molecular biology in the fields of oncology and neuronal metabolism. Since 2017, he's been the CEO and co-founder of Softcare Studios, a digital health startup specialized in developing virtual reality solutions for stress management and therapy education in patients undergoing medical treatments. He's also a regular contributor to online magazines on the topics of emerging tech, healthcare, and startup ecosystems. We have an extremely interesting conversation about how immersive technologies will change the game in the future of healthcare and how to leverage the power of our minds to improve our lives.

Natalie LePera graduated from Temple University in the winter of 2019, just a few months before COVID-19 led to the loss of m`any job opportunities. She has since worked in a few different companies, finding the right opportunity for her. Natalie is gaining experience in pharmacy research, working her way to some day earning a graduate degree in neuroscience/neuropharmacology or neuropsychopharmacology, a very neat field! In this episode, Natalie and I catch up about what it was like to find a job in the throes of a pandemic, how to advocate for a raise, and what we get wrong about Gen Z.A few references you may be interested in reading more about:Neurodegenerative diseases, https://medlineplus.gov/degenerativenervediseases.html Multiple myeloma, https://www.mayoclinic.org/diseases-conditions/multiple-myeloma/symptoms-causes/syc-20353378#:~:text=Multiple%20myeloma%20is%20a%20cancer,crowd%20out%20healthy%20blood%20cells. Neuropharmacology: in depth in neuroscience, focus on how anything crossing blood-brain barrier impacts brain cellsNeuropsychopharmacology, https://www.nature.com/npp/ Atypical plasticity inducers: “research chemicals”Johns Hopkins psychedelics research, https://hopkinspsychedelic.org/ R statistical software, https://www.r-project.org/ PubMed, https://pubmed.ncbi.nlm.nih.gov/ #wygupodcast #podcast #career #personalgrowth #professionalgrowth #mentor #rolemodel #professionaldevelopment #networking #pharma #pharmaresearch #research #recentgraduate

The Doctor Dads bring on returning guest Dr. Osvaldo Gaytan again to talk about mental health. Dr. Gaytan is a wealth of knowledge and has begun a new journey to change the approach of how mental/behavioral health challenges are treated. Getting the whole person well takes educating the patient on the importance of lifestyle medicine and the impact it has on their brain and mind. Diet, exercise, and mindfulness practices like meditation/prayer are pillars of our mental health and play a foundational role in healing. We discuss the importance of taking a holistic approach to one's mental health issues and why medication is not a long-term solution for anyone who struggles from mental/behavioral health challenges. We discuss: -The pillars of addressing mental health holistically- diet, exercise, mindfulness practice -Medications and their place in healing -The power of belief and how labels handicap individuals -The physiology of emotional/mental trauma -Taking a shamanistic approach to healing - and more...   Dr. Osvaldo Gaytan has been a child psychiatrist in El Paso for over 12 years.  He was born in North Central El Paso and is a proud Panther.  He graduated UTEP in 1989 with Honors and a Bachelors in Science, he received his MD/PhD in 1999 from The University of Texas Medical School at Houston with his PhD in Neuropharmacology, and he  completed his residency in Adult psychiatry in 2003 from Emory University in Atlanta. He also completed a three year research focused child fellowship from Emory in 2006. He has been published as a first author in over 20 peer reviewed journals and done many presentations locally and nationally.  Dr. Gaytan is committed to his patients and his community and is currently the Medical Director for the Child/Adolescent Unit at El Paso Behavioral Health System. He has also helped to establish The El Paso Child Mental Health Fund over the last few years as an effort to improve the mental health care of our children in the community.   Learn more about LA MENTE BEHAVIORAL HEALTH CALL 915-201-0199 to contact LA MENTE

This episode explores the effects of exposure to anesthesia in child hood and adolescence on how the brain processes alcohol later in life. Who would have thought that undergoing surgery as a youngster might impact your relationship with alcohol as an adult? Listen to this fascinating interview with Dr. Justine Landin to discuss her paper on this topic, titled "General anesthetic exposure in adolescent rats causes persistent maladaptations in cognitive and affective behaviors and neuroplasticity." It was published in the journal Neuropharmacology in 2019.

Benzodiazepines

Dr Ben Sessa was the first doctor to administer MDMA assisted therapy in the 21st century and Christopher Trudgian was one of his very first patients. They both join Professor David Nutt to answer the question… can MDMA be used therapeutically to treat addiction and/or PTSD?The links between childhood trauma/PTSD and adult addiction are very apparent. It is now well documented that MDMA has a therapeutic potential to treat PTSD could that mean that patients suffering with PTSD-related addiction could benefit from this type of therapy? To do this, Dr. Sessa had to examine the childhood trauma, sexual abuse and the selectively impaired fear response.Dr Sessa is a consultant child and adolescent psychiatrist working in adult addiction services and with custodial detained young people in a secure adolescent setting. Dr Sessa is currently a senior research fellow at Bristol, Cardiff and Imperial College London Universities, where he is conducting the UK's first clinical studies with MDMA-assisted therapy for the treatment of PTSD and alcohol dependence syndrome. In the last ten years he has worked on several UK-based human pharmacology trials as study doctor or as a healthy subject administering and receiving test doses of LSD, psilocybin, MDMA and ketamine.Ben Sessa - www.drsessa.comWhy MDMA Therapy for Alcohol Use Disorder and Why Now? Neuropharmacology (2017) - https://www.ncbi.nlm.nih.gov/pubmed/29126911Addaction/WeAreWithYou - https://www.wearewithyou.org.uk/MDMA - https://drugscience.org.uk/drug-information/mdma/MAPS MDMA - https://maps.org/research/mdmaMDMA Assisted-therapy training - https://maps.org/trainingMisuse of Drugs Act 1971 - http://www.legislation.gov.uk/ukpga/1971/38/contentsBecome a Drug Science Community Member: https://www.donate.drugscience.org.uk/Twitter: @ProfDavidNutt @Drug_ScienceA Fascinate Productions podcast for Drug Science ★ Support this podcast ★

Child Behavioral Health is such an important subject to create awareness and educate yourself if you have or work with children. The Doctor Dads sit down with Dr. Osvaldo Gaytan and he schools us on behavioral health. He shares his holistic approach to address behavioral health for children and adults using all the tools available to make the changes needed over time. Dr. Osvaldo Gaytan has been a child psychiatrist in El Paso for over 12 years. He is a graduated UTEP in 1989 with Honors and a Bachelors in Science , he received his MD/PhD in 1999 from The University of Texas Medical School at Houston with his PhD in Neuropharmacology, and completed his residency in Adult psychiatry in 2003 from Emory University in Atlanta. He also completed a three year research focused child fellowship from Emory in 2006. He has been published as a first author in over 20 peer reviewed journals and done many presentations locally and nationally. Dr. Gaytan is committed to his patients and his community and is currently the Medical Director for the Child/Adolescent Unit at El Paso Behavioral Health. He has also helped to establish The El Paso Child Mental Health Fund over the last few years as an effort to improve the mental health care of our children in the community.