Careers in Discovery

In this episode of Careers in Discovery, we're joined by Markus Gruell, Senior Vice President of Corporate Quality at Autolus, one of the UK's leading CAR-T therapy pioneers. Markus takes us behind the scenes of Autolus' journey from a UCL spinout to a commercial-stage Biopharma company, offering a rare look at how quality underpins every part of the drug development lifecycle. From working across GMP and GCP to collaborating with regulators on novel therapies, Markus shares what it means to lead quality in a fast-moving, high-growth Biotech business. We also explore Markus' personal journey - from pharmacist to QP, and from the NHS to senior leadership - guided by a passion for learning, a commitment to patient safety, and a belief in empowering his team through empathy and integrity. If you're curious about CAR-T, what quality looks like in a next-gen therapy company, or how to build a meaningful leadership career without a traditional plan, this episode is not to be missed.  

Our guest this week, Lara Campana is SVP of Research & Translational Science and a co-founder of Resolution Therapeutics, a company developing regenerative macrophage therapies for inflammatory and fibrotic diseases. In this episode of Careers in Discovery, Lara shares her journey from medical Biotechnology student in Milan to Biotech executive in the UK, and why she's been fascinated by macrophages ever since a single line in a university lecture hinted at their regenerative potential. We talk about the origins of Resolution, how the company grew from a trio of postdocs in a university lab to a clinical-stage Biotech, and the challenges of leading teams, building culture, and letting go as a founder. Lara also reflects on the mindset shift from academic research to pragmatic, patient-focused drug development - and the lessons she's learned along the way about influence, resilience, and finding space to think.

After nearly two decades at GSK, Pascal Lestrate took a leap into Biotech, joining Vicebio as Chief Preclinical Science Officer. In this episode of Careers in Discovery, Pascal shares how the shift from big pharma to early-stage Biotech gave him a chance to return to hands-on science - and start with a blank page. We explore the pioneering work Vicebio is doing on multi-pathogen respiratory vaccines using molecular clamp technology, including how their approach could reduce the number of injections needed while improving vaccine stability and access in low-resource settings. Pascal also reflects on his rich and varied career, from molecular biology and immunology to regulatory affairs, quality systems, and digital transformation. Along the way, he shares lessons on navigating major career transitions, leading without deep technical expertise, and how curiosity, values, and a willingness to take up space have shaped his path.

From New Delhi to Kentucky to Biotech founder, Lalit Sharma's journey into drug discovery has been one of relentless learning and ambition. In this episode, Lalit shares how his love for chemistry led him from a PhD in organic synthesis to leading cutting-edge drug discovery programs that reached clinical trials. Now the founder and CEO of a stealth-mode company tackling the data gap in AI-driven drug design, he reflects on the lessons of building small, high-impact teams, the importance of lifelong learning, and why good storytelling is as essential as good science. We also dive into the realities of building a Biotech from scratch, the role of luck (and preparation), and the power of collaboration across disciplines.  

In this episode of Careers in Discovery, we're joined by Jelena Aleksic, a serial entrepreneur, business coach, and director at SparkBio. Jelena shares her fascinating journey from genetics researcher to founder and start-up builder, including the lessons she learned from creating seven businesses across life sciences, tech, and even live entertainment. She opens up about her transition from academia to entrepreneurship, the importance of testing ideas early with customers, and why stepping away from a company can sometimes be the right choice. We also talk about embracing curiosity, building businesses that align with your passions and strengths, and how finding the right personal fit is key to both success and happiness.

After nearly two decades in big pharma, Lars van der Veen made the leap to entrepreneurship, co-founding iOnctura, a clinical-stage Biotech developing low-disruption therapies that target the tumour-stroma crosstalk to improve patient outcomes in cancer. In this episode of Careers in Discovery, Lars shares his journey from medicinal chemist to Biotech CSO, the lessons he learned building a company from scratch, and why taking the leap into Biotech offered him the chance to have real impact. He also talks about the science behind iOnctura's approach, how focusing on quality of life - not just survival - is shaping the future of oncology, and why every founder needs a plan B.  

In this episode of Careers in Discovery, Emma is joined by Juozas Gordevicius, founder of VUGENE, a bioinformatics company making complex multi-omics data analysis accessible to scientists across academia and industry. Juozas joined us to talk about his unconventional journey from computer science into the world of life sciences, how a chance meeting with an epigenetics professor changed his career path, and the story behind founding VUGENE. We also discussed the transformative impact of AI and machine learning on omics data, the realities of building a company from scratch, and why hiring that first team member is one of the scariest - but most rewarding - moments for any founder. This is a conversation about creativity, resilience, and building bridges between technology and biology.

In this episode of Careers in Discovery, we're joined by Mirko Buchholz, Co-founder and Managing Director at PerioTrap Pharmaceuticals, a Biotech company on a mission to revolutionize oral health by tackling one of the most widespread and underestimated diseases in the world - periodontitis. Mirko shares how a passion for chemistry and biology sparked his journey into drug discovery, and how his training in pharmacy gave him the unique ability to translate across scientific disciplines. He takes us through the ups and downs of building PerioTrap, from the science behind their microbiome-preserving approach to gum disease, to winning funding competitions, to a chance investor encounter that doubled their seed round. We also talk about resilience in Biotech, the realities of raising money for an overlooked therapeutic area, and why Mirko believes patience, curiosity, and adaptability are the essential traits for any scientist considering the leap into entrepreneurship.  

In this episode of Careers in Discovery, Tom meets with Annelise Vuidepot, Chief Technology Officer and UK Site Head at Immunocore, one of the UK's most successful Biotech companies. Annelise was there on day one in 2000, when Immunocore spun out from Oxford University, and she's been at the heart of the company's pioneering work in T-cell receptor-based therapies ever since. She shares her story of building a new technology from scratch, the long road to Immunocore's first approved drug, and how the company continues to evolve and innovate across oncology, infectious disease, and now autoimmunity. We explore what it takes to lead through 25 years of change, how Immunocore maintained a unified culture through hypergrowth, and why curiosity, resilience, and purpose are the keys to a fulfilling scientific career.  

In this episode of Careers in Discovery, Emma is joined by Robert Fletcher, co-founder and CEO of Nanolyx, a company developing sustainable antimicrobial technologies that could help solve one of the world's biggest challenges: antimicrobial resistance. Robert shares his unconventional path into Biotech - from working every entry-level job under the sun to returning to school in his thirties to study Biochemistry. Now leading a start-up while also working full-time in the lab at an early-stage Flagship Pioneering company, he reflects on the mindset needed to navigate entrepreneurship, the importance of mentorship, and why curiosity is more important than technical skills. We also dive into the science behind Nanolyx's unique nanoparticle-based technology, why they pivoted from FDA to EPA approval, and how the company is aiming to tackle everything from hospital infections to sustainability in surface disinfection.  

In this episode of Careers in Discovery, we're joined by Søren Bregenholt, CEO of Alligator Bioscience, a company developing tumour-directed immunotherapies to treat aggressive cancers such as pancreatic cancer. Søren shares his journey from academic immunologist to biotech CEO, including pivotal moments in his career - from his experiences at the Pasteur Institute, to building his Biotech education at Symphogen, to navigating the corporate world at Novo Nordisk. He reflects on lessons learned from leadership, fundraising, and decision-making at the top, and the importance of humility, structure, and courage in the face of uncertainty. We also explore what it really means to be a CEO, why "solving problems is your job," and how to strike the balance between hierarchy and creativity in growing Biotech companies. A compelling conversation about resilience, reinvention, and leading with clarity in an ever-evolving industry.

In this episode of Careers in Discovery, Emma meets with Chelsea Trengrove, CEO & co-founder of Neoclease, a start-up pioneering AI-designed, gene-specific editors that aim to overcome the safety, specificity, and scalability challenges of CRISPR-based therapies. Chelsea shares how her lifelong fascination with the brain and a PhD in neuroscience evolved into a career at the intersection of deep tech, healthcare, and entrepreneurship. From clinical trials and digital health to strategic partnerships and building a company from the ground up, her journey is a masterclass in adaptability, curiosity, and courage. She also opens up about the mindset shifts required to become a first-time CEO, the importance of saying yes (even when you're scared), and why meditation, martial arts, and mentorship have all shaped her leadership style.

From a childhood hospital bed to the founding of her own Biotech company, Ulrika Norin's journey into drug discovery has been anything but conventional. In this episode of Careers in Discovery, we speak with the founder and CEO of Serendo Therapeutics about her mission to transform treatment for autoimmune disease - starting with a breakthrough she made during her PhD. Ulrika shares how a long-standing fascination with the immune system led her to discover Endothelin A2 as a key regulator of autoimmunity, and how that science laid the foundation for Serendo. She talks openly about the leap from scientist to CEO, the pressures of leadership, and what it really means to build something from scratch. We also explore her time at Karolinska and Omnio, the importance of mentorship and networks, and why the best advice is to follow your gut - even if the path isn't linear. If you're curious about what it takes to spin out an idea into a company, balance passion with pressure, and lead with authenticity, this is one for you.  

What happens when a scientist trained in immunology finds herself leading biology at a cutting-edge mRNA Biotech? In this episode of Careers in Discovery, we sit down with Manuela Zonca, VP of Biology at NeoVac, to find out. Manuela shares her fascinating career journey across Europe - from academia in Spain and France to Biotech leadership in the UK - and the lessons she's learned along the way. She talks about the importance of following your gut, learning through mistakes, and why adaptability, teamwork, and mentorship are central to scientific success. We explore Manuela's role at NeoVac, a clinical-stage company pioneering mRNA delivery for vaccines, autoimmune disease, and more, and how she's helping expand the platform into new therapeutic areas. Whether you're thinking about transitioning from academia to industry, building a leadership career in science, or just curious about where mRNA is headed next, this episode is full of insight and inspiration.

In this episode of Careers in Discovery, we're joined by Jostein Dahle, Chief Technology Officer at Blue Wave Therapeutics. Jostein has spent over two decades in radionuclide therapy, taking discoveries from the lab to patients. Now, he's developing a new treatment for glioblastoma, one of the most aggressive and challenging brain cancers, using targeted radionuclide therapy derived from Norwegian seaweed. We talk about his journey from academia to Biotech, the hard lessons of building and scaling a company, and why following the science, staying agile, and knowing when to walk away are critical in drug discovery. Jostein also shares his experience of entrepreneurship in Biotech, the challenges of funding innovative treatments, and what's next for Blue Wave as they move towards the clinic.

This week on Careers in Discovery, we're joined by Karin Conde-Knape, Senior Vice President of Global Drug Discovery at Novo Nordisk. Karin's career has taken her from a PhD in cardiovascular science to leadership roles in big pharma, business development, and drug discovery. Now, she oversees early-stage research, external innovation, and portfolio strategy at one of the world's most successful pharmaceutical companies. We discuss how Novo Nordisk has transformed over the past seven years, the importance of human-centric drug discovery, and why AI, external partnerships, and a more holistic approach to disease biology are shaping the future of the industry. Tune in for brilliant insights on navigating an international career, the power of cross-disciplinary thinking, and why leadership in science requires both vision and adaptability.

This week on Careers in Discovery, we welcome back Dave Hallett, now Chief Scientific Officer at Recursion, following the recent merger with Exscientia. The last five years have been transformative for Dave, from leading AI-driven drug discovery at Exscientia to navigating one of Biotech's biggest IPOs and stepping into the CEO role in a challenging market. Now, he's focused on proving that AI-designed medicines can deliver real impact, with clinical results beginning to emerge. We discuss the evolution of AI in drug discovery, the lessons Dave has learned leading a publicly listed company, and why the industry must focus on reducing drug development failure rates to make new medicines more accessible. A fascinating conversation with a leader at the forefront of Biotech innovation.  

This week on Careers in Discovery, Emma sits down with Mikko Turunen, founder and CSO of RNatives, a company pioneering RNA activation for therapeutic use. Mikko's journey has taken him from academia to Biotech entrepreneurship, with more than 25 years in gene therapy. He shares the story behind RNatives, the challenges of launching a company in a tough funding climate, and the resilience required to keep going when setbacks arise. Emma and Mikko talk about navigating the transition from scientist to entrepreneur, building a startup from the ground up, and the importance of networking, persistence, and adaptability in the Biotech world. This episode offers a candid look at what it takes to turn breakthrough science into a thriving business.

This week on Careers in Discovery, Emma is joined by Josef Christensen, Chief Operating Officer at ImmuneAGE Bio. Josef started out in academia, completing a PhD at Harvard Stem Cell Institute, before moving into consulting, venture capital, pharma, and Biotech startups. Now, he's leading efforts to rejuvenate the immune system and combat age-related disease. He shares his journey from scientist to business leader, the challenges of fundraising in today's climate, and why mentorship, sponsorship, and big pharma experience can be game changers for those looking to enter Biotech. Josef's insights are essential listening for scientists, entrepreneurs, and anyone navigating career transitions in drug discovery.  

In this episode of Careers in Discovery, Tom sits down with Dominique Verhelle, Co-Founder, President and CEO of NextRNA Therapeutics, a company pioneering the use of long non-coding RNAs in drug discovery. Dominique takes us through her unconventional journey - from aspiring flight attendant to Biotech entrepreneur - sharing the pivotal moments that shaped her career. She talks about the challenges of leading a startup through uncertainty, balancing science and business as both CSO and CEO, and why strategic timing is key in career growth. We also discuss the evolution of the dark genome field, NextRNA's recent partnership with Bayer, and what's next for this exciting company as it moves towards the clinic. A fascinating conversation on leadership, resilience, and pushing the boundaries of biology.  

In this episode of Careers in Discovery, we're joined by Christian Schroeter, Chief Operating Officer and Managing Director at Topas Therapeutics. Christian's work focuses on developing immune tolerance therapies for autoimmune diseases, using nanoparticle technology to retrain the immune system. With Topas recently completing a Phase 2a trial in coeliac disease, he shares the excitement of leading a Biotech at a critical stage and the challenges of securing funding to drive the next phase of development. He also reflects on his career journey from academia to Big Pharma and now Biotech, the lessons he's learned from global leadership roles, and why stepping outside your comfort zone - sometimes into the “crazy” - can lead to the most rewarding opportunities. If you're interested in the science behind immune tolerance, the transition from pharma to Biotech, and what it takes to navigate a career in life sciences, this is an episode you won't want to miss.

In this episode of Careers in Discovery, Emma is joined by Theonie Anastassiadis, Senior Principal at Flagship Pioneering and Founding President of Prologue Medicines. Theonie's work is all about uncovering ground-breaking biology and turning it into transformative Biotech companies. She shares her journey from academia to venture creation, her experience co-founding multiple Biotech start-ups, and how Prologue Medicines is harnessing viral proteins to develop innovative therapeutics. She also dives into the importance of culture in scientific innovation, the role of mentorship in shaping careers, and why curiosity is the most powerful tool a scientist can have. If you're interested in the intersection of cutting-edge science and entrepreneurship, the realities of Biotech leadership, and how to create an impact beyond the lab, this is an episode you won't want to miss.

On this episode of Careers in Discovery, we spoke with Riccardo Panella, Founder and Chief Scientific Officer of Resalis Therapeutics, and Associate Professor at the Center of RNA Medicine in Copenhagen. Riccardo shared his journey from academia to Biotech entrepreneurship, discussing how a serendipitous discovery during his postdoctoral research at Harvard led him to explore the role of microRNAs in metabolism. He delved into the challenges and rewards of founding Resalis Therapeutics, highlighting the importance of resilience in securing funding and the differences between academic and commercial science. We also explored his perspectives on leadership, the value of collaboration, and the advice he would give to early-career scientists. A compelling conversation about adaptability, perseverance, and the pursuit of translational science.

This week on Careers in Discovery, we sat down with Kathryn Penkus Corzo, President & COO of bit.bio, to talk about her journey from clinical pharmacy to leading a company at the forefront of cell therapy and drug discovery. Kathryn shared how bit.bio is using machine learning and cell coding to create scalable, precision-engineered human cells - both for research and as potential therapies. She also reflected on her career path, from cold calling her way into Roche in Switzerland to leadership roles at Lilly, Sanofi, and Takeda, and why taking risks, embracing change, and working internationally shaped her success. We also talked about culture, mentorship, and knowing when to push yourself - and why stepping outside your comfort zone is the key to real growth. A great conversation with a leader who's driving the future of cell therapy.

This week on Careers in Discovery, we spoke with Graham Dempsey, CSO of Quiver Bioscience, to talk about his journey from a passion for sports medicine to leading a company at the cutting edge of neuroscience drug discovery. Graham shared how Quiver is combining stem cell models, optogenetics, and AI to study brain diseases at an unprecedented scale, and what he's learned from spending over a decade growing within the same company, from Senior Scientist to CSO. We also explored the realities of Biotech growth, the challenges of translating research into real-world impact, and why persistence is key to success in this space. A fascinating insight into the future of brain-targeted drug development.

This week on Careers in Discovery, we sat down with Marco Schmidt, CSO of biotx.ai, to talk about AI, Biotech, and the future of drug discovery. Marco's career has taken him from Biochemistry to Biotech start-ups, where he's using causal inference to reshape clinical trials and drug development. We explored the evolution of AI in science, the rise of tech-bio companies, and why he believes this is the best time in history to be a scientist. We also got into the mindset shift needed for scientists moving into business - and why failure isn't just inevitable, but essential. Join us for a really thought-provoking episode.

This week on Careers in Discovery, we're joined by Tommi Kainu, Chairman of GlyProVac, a Biotech developing bacterial vaccines with the potential to tackle antimicrobial resistance. Tommi's career has taken him from medicine and research to consulting at BCG and leadership roles in Biotech. He shared insights on GlyProVac's work, why commercial thinking is key in drug development, and lessons from his time at Bavarian Nordic - including the unexpected rise of the MPOX vaccine. His advice for scientists moving into industry? Start with the end in mind. A great conversation on science, strategy, and the business of Biotech.

This week, Emma spoke with Martijn Van De Bunt, Chief Scientific Officer at Cytoki Pharma, a pioneering Biotech in Denmark developing IL-22-based therapies for obesity, type 2 diabetes, and inflammatory bowel disease. Martijn shared insights from his journey from medicine and academia to leading a lean, globally connected Biotech team advancing transformative therapies. Martijn discussed the pivotal moments in his career, from a PhD at Oxford that sparked his passion for impactful science, to his tenure at Novo Nordisk, and ultimately to joining Cytoki Pharma. Along the way, he emphasised the importance of adaptability, the nuances of transitioning between academia and industry, and the role of networks and teamwork in achieving success. With Cytoki Pharma approaching critical milestones in their clinical studies, Martijn also reflected on the challenges and excitement of developing ground-breaking treatments in a dynamic Biotech environment. Tune in for a conversation packed with advice on career growth, the evolution of drug discovery, and the human side of building innovative Biotech companies.

This week, we welcomed Jordi Carreras-Puigvert, Chief Scientific Officer and Co-Founder of Phenaros, a Swedish company revolutionising drug discovery at the intersection of artificial intelligence and life sciences. Jordi shared his journey from personal tragedy inspiring a career in science, to leading a cutting-edge platform combining high-content microscopy and AI to accelerate therapeutic development, especially in rare diseases. Jordi delved into his unconventional career path, including his foundational work in phenotypic drug discovery, insights on transitioning from academia to biotech, and the critical role of mentorship and networking in shaping his success. He also explored the transformative potential of AI in drug development, emphasising the importance of generating high-quality data to drive innovation. Listen in for a brilliant conversation about leveraging technology to address unmet medical needs, and the power of adaptability in forging a meaningful career in science.

In this episode of Careers in Discovery, Emma sits down with Henri Huttunen, Chief Scientific Officer at Herantis Pharma, a Finnish biotech developing ground-breaking therapies for Parkinson's and related neurodegenerative diseases. Henri shares the exciting progress on their next-generation molecule that crosses the blood-brain barrier and their innovative approach to tackling the challenges of clinical trials in this field. Henri reflects on his journey, from his early days in academic research to founding start-ups and leading Herantis' mission to develop disease-modifying treatments. He talks about the importance of balancing scientific rigour with innovation, navigating the risks of challenging established dogmas, and the role personal passion plays in driving success. This episode is packed with insights into the cutting edge of neurodegenerative research, the lessons learned from taking bold career steps, and the inspiration behind Henri's dedication to improving patients' lives. Tune in for an inspiring and thought-provoking conversation.  

In this episode of Careers in Discovery, Emma is joined by Arvid Söderhall, the first employee and project lead at Empros Pharma, as he shares his unique journey from physicist to biotech innovator. Arvid unveils the vision behind Empros Pharma's pioneering work to combat obesity with a pharmaceutical approach to gastric bypass surgery. Emma and Arvid's conversation delves into the evolution of Empros Pharma, the challenges of developing innovative treatments in a competitive field, and the critical importance of adapting to an ever-changing market landscape. Arvid also reflects on his career trajectory, discovering his leadership potential, and the value of seizing unexpected opportunities along the way. A must-listen episode for biotech enthusiasts, aspiring leaders, and anyone passionate about making an impact in the life sciences industry.  

This week on Careers in Discovery, we're joined by Jonas Dyhrfjeld-Johnsen, Chief Development Officer and Managing Director at Acousia Therapeutics, a company developing innovative therapies to preserve and restore hearing. Jonas shares his journey from academic Biophysics to Biotech leadership, reflecting on the importance of adaptability and continuous learning. We discuss Acousia's groundbreaking work targeting sensory hair cells and their Phase 2 trial aimed at preventing chemotherapy-induced hearing loss, as well as the challenges and rewards of leading a lean, virtual Biotech. An inspiring conversation about tackling a major global health issue and building a meaningful career in science.

Could microglia hold the key to treating neurodegenerative diseases? This week on Careers in Discovery, Emma Hobbs is with David Gray, Chief Scientific Officer at Vigil Neuroscience, who is pioneering new approaches to harness the brain's immune system. David shares his unique career journey, from aspiring author to leading drug discovery programs at Pfizer and now in Biotech. He reflects on the power of curiosity, mentorship, and cross-disciplinary learning that shaped his path to leadership. In this episode, David and Emma discuss Vigil's ground-breaking work in targeting ALSP and Alzheimer's disease, the lessons he's learned transitioning from big pharma to Biotech, and why having fun is essential to building a fulfilling scientific career. Join us for an inspiring conversation about leadership, innovation, and advancing treatments for patients in need.

This week on Careers in Discovery, we're joined by Rodrigo Santos, CTO of clock.bio, a company pushing the boundaries of cellular rejuvenation to tackle age-related diseases. Rodrigo shares the fascinating work happening at clock.bio, including their hypothesis-free approach to uncovering rejuvenation factors and the creation of their “Atlas of Rejuvenation Factors.” We also got to hear about Rodrigo's incredible journey - from growing up in a small farming village in Portugal to leading cutting-edge biotech companies - all driven by his passion for cellular plasticity and the transformative potential of Yamanaka factors. Along the way, he reflects on the lessons he's learned, balancing science and business, and why emphasis on execution is key. Join us as we explore the science of rejuvenation, the innovation behind it, and the mindset needed to succeed in this ever-evolving field.

In this episode of Careers in Discovery, we had the pleasure of talking to Jen Fortune, Chief Operating Officer at Precede Biosciences. Jen shared her fascinating journey, from a PhD in chemistry to consulting, big pharma, and now driving operations in a cutting-edge liquid biopsy company. Her story is one of curiosity, grit, and seizing opportunities alongside incredible people. We also explored the game-changing potential of Precede's work in epigenomics and how their innovative platform is helping to unlock the future of precision medicine. Along the way, Jen reflects on her passion for mentoring, the importance of fostering diversity, and how embracing your authentic style can drive both personal and professional success. This is a conversation full of practical insights and inspiration for anyone navigating a career in science, leadership, or the life sciences industry.

In this episode of Careers in Discovery, we're with James Field, the founder and CEO of LabGenius, as we discuss his remarkable journey from PhD student to biotech entrepreneur. James reveals the vision behind LabGenius, a company harnessing the power of machine learning and protein engineering to transform therapeutic antibody discovery. Our conversation explores the challenges of early-stage entrepreneurship, the importance of surrounding yourself with the right people, and the transition from being a scientist at the bench to leading a multidisciplinary team. James also reflects on the role of focus, perseverance, and tackling unsolved problems in building a world-class biotech organisation. A must-listen episode for aspiring founders, scientists, and anyone curious about the intersection of AI and biology.

This week on Careers in Discovery we're with Katie Binley, CSO of Ikarovec, a gene therapy company tackling chronic eye diseases like geographic atrophy and age-related macular degeneration. Katie shares Ikarovec's incredible journey—from starting out in the middle of a pandemic to securing a £5 million funding extension—and how a small, tight-knit team made it all happen. Katie tells us all about the science behind their work, how her career has evolved (including 25 years at Oxford Biomedica), and why stepping out of your comfort zone and creating your own luck are so important. It's a brilliant conversation full of insights into leadership, innovation, and building something great on a shoestring budget.

In this week's episode of Careers in Discovery we're talking with Lucas Arruda, CSO at CuraCell, a biotech on a mission to push the boundaries of cancer treatment using TIL (tumour-infiltrating lymphocyte) therapy. Lucas shares how CuraCell is working to expand TIL treatment beyond "hot" tumours like melanoma to tougher "cold" tumours, including prostate cancer—offering hope for patients who often have limited options. Lucas opens up about his path from academia to industry, driven by a lifelong love of science and a desire to make a real difference in people's lives. He talks about the unique challenges of his role, juggling hands-on lab work, strategic planning, and managing a small team in a high-stakes environment. He also reflects on the key skills he's learned along the way—adaptability, risk-taking, and staying curious. As CuraCell prepares to start its first clinical trials in 2025 Lucas gives us an inside look, sharing honest insights into making the shift from academic research to the fast-paced demands of industry. Join us this week for a thoughtful, inspiring conversation with a scientist at the cutting edge of cancer therapy.

In this episode of Careers in Discovery, we're joined by Lindsay Davies, Chief Scientific Officer at NextCell Pharma. Lindsay's work focuses on harnessing the potential of umbilical cord-derived cells to treat autoimmune diseases, especially type 1 diabetes. She shares her inspiring journey from academia to leading cutting-edge cell therapy trials, driven by a commitment to patient-centred science and innovation. Lindsay also highlights her role in mentoring the next generation of scientists and her team's exciting plans for QVance, a new venture to support advanced therapies with robust quality analytics. If you're curious about the future of cell therapy, the real-world impact of innovative science, and a career built on passion and purpose, this is an episode you won't want to miss.

In this episode of Careers in Discovery, we welcome Torleif Gjølberg, CSO and co-founder of Authera, a biotech innovator transforming antibody and albumin-based therapeutics. Torleif takes us through Authera's journey from its academic beginnings in Oslo to becoming a revenue-generating company with a clear mission: to drive therapeutic innovation. He reflects on his path from molecular biology to biotech entrepreneurship, highlighting the power of curiosity, adaptability, and having the courage to bridge science and business. If you're curious about making the leap from academia to biotech, or want to hear what it really takes to build a company with heart, tune in—you won't want to miss this episode.

In this episode of Careers in Discovery, we're joined by Christian Code, Chief Technology Officer at Dianox, as we explore how his career journey took him from being a young science enthusiast in Canada to leading a cutting-edge biotech startup in Denmark. Christian opens up about the unexpected path that led him into the world of diagnostics and therapeutics, where he and his team are now using AI to uncover new possibilities for drug discovery and push the boundaries of what's possible in healthcare. He shares some hard-earned lessons about curiosity, the importance of connecting with others, and finding your own unique strengths, whether you're in a lab or building a business. Join us for a thought-provoking discussion on embracing opportunities, following your interests, and letting curiosity guide you to places you never thought you'd end up.

In this episode of Careers in Discovery I sit down with Simon Young, VP of Translational Science at C4X Discovery. Simon's career has taken some fascinating twists and turns, from veterinary medicine to electrical engineering, and eventually into diagnostics, drug discovery and precision medicine. He shares how those experiences have shaped his approach today, and how staying flexible, taking on new challenges and stepping out of your comfort zone have helped him to build an exciting career.

This week on Careers in Discovery, I'm joined by Dr Peter Pack, an influential figure in the Biotech industry whose journey has taken him from Germany to the dynamic Biotech landscape of the UK, where he now operates as a strategic partner and advisor to Private Equity firms and startups. In our conversation, Peter shared his diverse experience, including his time as a CEO for nearly 20 years and his current role mentoring young biotech teams. He offered insights into the differences between the Biotech industries in Germany and the UK, the importance of building strong networks, and his passion for supporting innovative startups. Peter also reflected on his early inspirations in science, the development of groundbreaking technologies at Morphosys, and the valuable lessons he has learned about commercialization and strategic decision-making. He emphasized the importance of collaboration, learning from mistakes, and the critical role of supportive investors. Join us as we explore Peter's fascinating career, his views on the future of biotech, and the key factors that contribute to successful leadership in this ever-evolving field.

In this episode of Careers in Discovery we sit down with Adam Glen, co-founder of Unicorn Biotechnologies, to talk about his journey from academia to building a biotech company that's tackling one of the biggest pain points in life sciences: manual cell culture. Adam shares the frustrations that led him to start his own company, explaining how his experiences in academia and industry shaped his vision. He talks about the challenge of scaling up stem cell manufacturing and how Unicorn Biotechnologies' approach strips complex problems back to their fundamentals, making the whole process more efficient and accessible. In a candid conversation, Adam also reflects on his personal journey—balancing his love of science with a growing entrepreneurial drive and learning from the highs and lows of start-up life. He offers advice for those thinking about making the leap from research to business, emphasising the importance of being driven by curiosity, embracing uncertainty, and continuously learning. This episode is a must-listen for anyone interested in biotech innovation, entrepreneurship, and the real-world challenges of scaling scientific breakthroughs.

In this episode of Careers in Discovery we're joined by Volker Herrmann, CEO of Sonata Therapeutics, for a fascinating conversation about his journey from a cardiologist to a biotech leader. Volker shares the moments in his career that led him to question the traditional approaches in medicine, which sparked his innovative thinking at Sonata Therapeutics. He discusses the company's unique approach to using "network medicines" to potentially reprogram disease cells to fight illness, akin to a form of "biological judo." Volker also reflects on his career transitions, from leading Pfizer's CNS Pain franchise to spearheading a service and solution business aimed at improving patient outcomes beyond pharmaceuticals. Throughout the discussion, he emphasizes the importance of authenticity, purpose, and impact in driving success within the biotech industry. He offers advice on maintaining a strong sense of urgency, fostering a purpose-driven culture, and how to navigate the difficult elements of leadership in a fast-paced environment. Join us this week as we discuss the challenges and rewards of leading a biotech company with a focus on innovative patient-centric solutions.

In this week's episode of Careers in Discovery, we sit down with Marcin Paduch, Head of Platform Biology at Metaphore Biotechnologies. Marcin shares his insight into the exciting work happening at Metaphore, where they're using the power of biomimicry and machine learning to develop new therapeutics. He explains how their MIMIC platform helps tackle tough therapeutic challenges, particularly in areas like cardiometabolic diseases and immunology, and shares the story behind their recent collaboration with Novo Nordisk. Marcin also opens up about his personal journey into science, starting with a childhood surrounded by scientists and doctors, and how that led him into a career spanning structural biology, protein engineering, and ground-breaking start-ups like Grail and Arsenal Bio. He talks about the lessons he's learned along the way, like the importance of staying curious, embracing technology, and being open to unexpected opportunities. Join us for a fascinating discussion on the intersection of science, technology, and the evolving landscape of drug discovery.

In this latest episode of Careers in Discovery, we sit down with Alistair Henry, the new Chief Scientific Officer at UCB, to talk about his remarkable 26-year journey with the company. Alistair shares his passion for science and how it led him from a curious teenager to a leader in drug discovery, working on ground-breaking projects in immunology and neurology. Alistair opens up about the excitement and challenges of his new role, the importance of always looking ahead, and how he balances immediate priorities with long-term innovation. He also reflects on the pivotal moments in his career, from his unexpected entry into pharma to his deepening focus on making a real difference for patients. Alistair offers honest and practical advice for those starting out in their scientific careers. He emphasizes the importance of staying curious, connecting with others, and being open to stepping out of your comfort zone. He also talks about the power of collaboration and how building a strong, open, and innovative culture has been key to his success at UCB. If you're interested in the human side of a career in science and what it takes to lead with purpose, this episode is full of insights from someone who's done it all.

This week on Careers in Discovery, we're delighted to be joined by Kenny Duncan, SVP of Chemistry at Accent Therapeutics, where we explore the evolving landscape of drug discovery and the critical role chemistry plays in advancing new therapies. Kenny takes us through his incredible career journey, from his early passion for chemistry to becoming a leader in Boston's thriving biotech industry. We discuss his work on RNA-modifying proteins and how his team is tackling the challenges of targeting complex biology with innovative chemistry. In this episode, Kenny and I discuss the strategic thinking required to drive success in biotech, the importance of building strong, multidisciplinary teams, and the lessons he's learned on his path from scientist to executive. He also shares valuable advice on following your passions and the importance of staying adaptable in a fast-changing industry. Join us for a thought-provoking conversation with Kenny Duncan, where we unpack the future of drug discovery and the crucial role chemistry continues to play in shaping the industry.

Could AI be the key to reducing the high failure rate in drug discovery? This week on Careers in Discovery, we explore this critical question with Richard Law, Chief Business Officer at Exscientia, who has been at the forefront of integrating AI into the Biotech industry for decades. Richard shares his fascinating career journey, from his early days as a Computational Chemist to his current role leading Business Development in one of the most innovative companies in drug discovery. He offers unique insights into how AI is not only accelerating the process but also increasing the likelihood of success in developing new therapies. In this episode, Rich and I discuss the transformative potential of AI in drug discovery, explaining how these technologies are changing the game by improving the quality of molecules and enhancing the precision of clinical trials. He also reflects on the challenges of adapting to a rapidly evolving industry and the importance of staying open to new ideas and learning from those around you. Join us for an inspiring conversation with Richard Law, where we delve into the future of drug discovery and the revolutionary role AI is set to play.

This week I'm joined by Hazel Jones, CEO of Enhanc3d Genomics. Hazel shares her journey from her early days in Biotech to leading a company at the cutting edge of 3D genomics. We explored Hazel's career path, her transition into a CEO role and her insights on leadership, the significance of networking, and balancing professional and personal life.

This week on Careers in Discovery, we are joined by Peter Pack, an influential figure in the biotechnology industry with a career spanning over two decades. Peter's journey has taken him from Germany to the dynamic biotech landscape of the UK, where he now operates as a strategic partner and advisor to private equity firms and startups. In our conversation, Peter shares his diverse experiences, including his time as a CEO for nearly 20 years and his current role mentoring young biotech teams. He offers insights into the differences between the biotech industries in Germany and the UK, the importance of building strong networks, and his passion for supporting innovative startups. Peter also reflects on his early inspirations in science, the development of groundbreaking technologies at Morphosys, and the valuable lessons he has learned about commercialization and strategic decision-making. He emphasizes the importance of collaboration, learning from mistakes, and the critical role of supportive investors. Join us as we explore Peter's fascinating career, his views on the future of biotech, and the key factors that contribute to successful leadership in this ever-evolving field. Don't miss this episode full of insights from a biotech veteran who continues to shape the industry.