Podcasts about CSO

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Best podcasts about CSO

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Latest podcast episodes about CSO

Medical Spa Insider
Greatest Hits: Pivoting and Priorities: Advice from a Top Leadership Coach

Medical Spa Insider

Play Episode Listen Later Aug 13, 2025 46:33


In this greatest hits episode, we revisit a conversation between AmSpa President and CSO, Cathy Christensen, and top leadership coach and bestselling author Sohee Jun, PhD. They discuss the myth of balance, Jun's journey into leadership coaching and her advice for overcoming challenges as a business leader. Their conversation includes: Why she's allergic to the word “balance;” Integrating our priorities and thinking about our values; Her journey to organizational psychology and leadership coaching; What working with a leadership coach looks like and who her clients are; Advice for cultivating a team of leaders; Recognizing when to pivot and elevate your leadership style; The challenge of leading multigenerational teams; Her keynote at the 2023 Women in Aesthetics Leadership Conference. Reignite your passion to lead with mentorship from aesthetic innovators, entrepreneurs and renowned experts at the 2025 Women in Aesthetics Leadership Conference, October 3 - 5 at Terranea Resort in Southern California. Learn more about the connections and experiences that await you at experiencewalc.com. --- Music by Ghost Score

To The Point - Cybersecurity
The Evolving Cyber Threat Landscape in Healthcare: Insights from Fortified Health Security's Russell Teague

To The Point - Cybersecurity

Play Episode Listen Later Aug 12, 2025 23:54


On this episode of To the Point Cybersecurity Podcast, hosts Rachel Lyon and Jonathan Knepher dive deep into the evolving threat landscape in healthcare cybersecurity with special guest Russell Teague, CSO at Fortified Health Security. With over three decades of experience across sectors like healthcare, pharma, and finance—and as a contributor to the White House National Cybersecurity Healthcare Strategy—Russell brings incredibly valuable insights to the table. Together, they unpack the most pressing cyber threats facing healthcare organizations today, including ransomware as a service, third-party risks, and the growing impact of AI on both offense and defense. Russell discusses the unique challenges rural and small healthcare providers face, the critical importance of operational resiliency and incident readiness, and why data management remains a top priority in protecting patient information. Tune in for practical advice, free resources, and expert analysis of what's needed to stay ahead of attackers in one of the world's most targeted industries. Whether you're a cybersecurity professional, healthcare leader, or just interested in the intersection of technology and patient care, this episode is packed with insights you won't want to miss. For links and resources discussed in this episode, please visit our show notes at https://www.forcepoint.com/govpodcast/e345

Smart Biotech Scientist | Bioprocess CMC Development, Biologics Manufacturing & Scale-up for Busy Scientists
179: How Mesenchymal Stromal Cells Are Transforming Care for Diabetes and Autoimmune Diseases with Lindsay Davies - Part 1

Smart Biotech Scientist | Bioprocess CMC Development, Biologics Manufacturing & Scale-up for Busy Scientists

Play Episode Listen Later Aug 12, 2025 23:06


The key to conquering autoimmune diseases and type 1 diabetes may lie not in replacing lost cells, but in retraining the immune system using cells already within the body.Biotech is increasingly exploring stem cell therapies, but a quieter revolution is brewing: stromal cell therapy. These master “coordinators” aren't about rebuilding tissues molecule by molecule - instead, they orchestrate an anti-inflammatory response, offering new hope for conditions once considered incurable.In this episode of the Smart Biotech Scientist Podcast, host David Brühlmann speaks with Lindsay Davies, a leading expert in advanced therapies. She is the CSO at NextCell Pharma, consultant at CellTherEx, and co-founder of QVance, a QC analytics provider for ATMPs. Recently elected Vice President Elect for Europe at ISCT, Lindsay also chairs its European Industry Committee and serves on multiple task forces. With over 20 years bridging academia and industry, she's helped shape the full lifecycle of cell-based therapies, from development to commercialization.Here are three reasons why you can't miss this episode:Stromal Cells - The Unsung Heroes: Discover the essential distinction between stem cells (the “builders”) and stromal cells (the “coordinators”), and how harnessing the latter's unique immune-modulatory powers is unlocking treatments for diabetes, COVID-19, and autoimmune diseases.A Manufacturing Mindset Shift: Lindsay explains why scaling out cell therapies defies the “plug-and-play” approaches of traditional biologics manufacturing. With cell quality so sensitive to environmental shifts, the key lies in process simplicity, early regulatory collaboration, and deep biological understanding - especially when donor variability enters the mix.Allogeneic Therapies Made Real: Thanks to umbilical cord-derived stromal cells, treatments can be manufactured at scale, stored frozen, and delivered on demand - no patient matching required. The result? Outpatient infusions, no side effects, and effects lasting up to five years, dramatically simplifying lives for those with chronic inflammatory conditions.Ready to rethink how cell therapies are changing medicine - and what it could mean for your bioprocessing strategy? Hit play and find out how Lindsay Davis is redefining what's possible in advanced therapy manufacturing.Connect with Lindsay Davis:LinkedIn: www.linkedin.com/in/lindsay-c-daviesWebsite: www.nextcellpharma.comIf you're interested in breakthroughs in cell therapy, here's what some of our previous guests have shared from the front lines of innovation:Episodes 105-106: From Proteins to Cell Therapy: Why ATMPs Aren't Just Complex Biologics with Oliver KraemerEpisodes 109-110: Spinning Like Earth: Designing Low-Shear Bioreactors for Better Cell Culture with Olivier DetournayEpisodes 125-126: How to Enhance Cell Engineering Using Mechanical Intracellular Delivery with Armon ShareiNext step:Book a free consultation to help you get started on any questions you may have about bioprocess development: https://bruehlmann-consulting.com/callDevelop bioprocessing technologies better, faster, at a fraction of the cost with our 1:1 Strategy Call: The quickest anJoin 500+ CGT leaders at Advanced Therapies Europe 2025 (September 2-4, Barcelona) for live case studies, regulatory insights, and exclusive collaboration opportunities. As a Smart Biotech Scientist listeners you'll save 20% with code SMARTPODCAST20 – Register hereSupport the show

The Sustainability Communicator
How Chief Sustainability Officers advance sustainability storytelling

The Sustainability Communicator

Play Episode Listen Later Aug 8, 2025 31:54


In this episode, Mike sits down with Erik Hansen, Chief Sustainability Officer at Workday, to explore how CSOs have evolved into the lead communicators for corporate sustainability. Erik shares insights on building trust through transparency, making the business case for sustainability initiatives, and how companies are increasingly being asked detailed sustainability questions in hundreds of RFPs. The conversation covers practical strategies for working with legal teams on compliant communications, measuring the success of sustainability storytelling, and thinking beyond company silos to advocate for industry-wide change.Connect with Erik Hansen on LinkedIn.Learn more about Workday's sustainability strategy. Follow Mike on LinkedInSubscribe to The Sustainability Communicator LinkedIn newsletterSign up for Hower Impact's ENGAGE newsletterVisit the Hower Impact website.Contact Mike.

QSR Magazine's Fast Forward
Why is Beverage Innovation So Hot in QSR? with Botrista's Jason Valentine

QSR Magazine's Fast Forward

Play Episode Listen Later Aug 7, 2025 32:07


Jason Valentine, CSO at Botrista, joins QSR editorial director Danny Klein to break down what's perhaps the hottest battleground in quick service right now. What trends are driving the beverage movement? What do Gen Z want? How can restaurants innovate without breaking the brand? We get into all of that and a lot more.

BioSpace
From Chat Bots to World Order: The Race for the 21st Century's Operating System

BioSpace

Play Episode Listen Later Aug 7, 2025 20:12


In this thought-provoking episode, Cresset Group's CSO, Mark Mackey, and VP of AI, Mutlu Dogruel, dissect the emerging geopolitical battle for AI supremacy, revealing how China's DeepSeek model fundamentally disrupted the AI landscape by achieving GPT-4 level performance for just $6 million versus OpenAI's reported $100+ million investment. The discussion exposes a critical divide in global AI governance: Europe's "regulatory fortress" approach with the AI Act creates strict but vague rules that leave companies navigating a complex maze, while the US employs a "Wild West" philosophy of sector-specific oversight and red-teaming strategies. In the race for global AI dominance, China is leaping ahead of the US and the EU.This episode is presented in partnership with Cresset.Host⁠⁠⁠⁠⁠⁠⁠Lori Ellis⁠⁠⁠⁠⁠⁠⁠, Head of Insights, BioSpaceGuestsMutlu Dogruel, VP of AI, CressetMark Mackey, CSO, CressetDisclaimer: The views expressed in this discussion by guests are their own and do not represent those of their organizations.

The CyberWire
Chasing Silicon shadows.

The CyberWire

Play Episode Listen Later Aug 6, 2025 37:47


Two Chinese nationals are arrested for allegedly exporting sensitive Nvidia AI chips. A critical security flaw has been discovered in Microsoft's new NLWeb protocol. Vulnerabilities in Dell laptop firmware could let attackers bypass Windows logins and install malware. Trend Micro warns of an actively exploited remote code execution flaw in its endpoint security platform. Google confirms a data breach involving one of its Salesforce databases. A lack of MFA leaves a Canadian city on the hook for ransomware recovery costs. Nvidia's CSO denies the need for backdoors or kill switches in the company's GPUs. CISA flags multiple critical vulnerabilities in Tigo Energy's Cloud Connect Advanced (CCA) platform. DHS grants funding cuts off the MS-ISAC. Helicopter parenting officially hits the footwear aisle. Remember to leave us a 5-star rating and review in your favorite podcast app. Miss an episode? Sign-up for our daily intelligence roundup, Daily Briefing, and you'll never miss a beat. And be sure to follow CyberWire Daily on LinkedIn. CyberWire Guest Today we are joined by Sarah Powazek from UC Berkeley's Center for Long-Term Cybersecurity (CLTC) discussing her proposed nationwide roadmap to scale cyber defense for community organizations. Black Hat Women on the street Live from Black Hat USA 2025, it's a special “Women on the Street” segment with Halcyon's Cynthia Kaiser, SVP Ransomware Research Center, and CISO Stacey Cameron. Hear what's happening on the ground and what's top of mind in cybersecurity this year. Selected Reading Two Arrested in the US for Illegally Exporting Microchips Used in AI Applications to China (TechNadu) Microsoft's plan to fix the web with AI has already hit an embarrassing security flaw  (The Verge) ReVault flaws let hackers bypass Windows login on Dell laptops (Bleeping Computer) Trend Micro warns of Apex One zero-day exploited in attacks (Bleeping Computer) Google says hackers stole its customers' data in a breach of its Salesforce database (TechCrunch) Hamilton taxpayers on the hook for full $18.3M cyberattack repair bill after insurance claim denied (CP24) Nvidia rejects US demand for backdoors in AI chips (The Verge) Critical vulnerabilities reported in Tigo Energy Cloud connect advanced solar management platform (Beyond Machines) New state, local cyber grant rules prohibit spending on MS-ISAC (StateScoop) Skechers skewered for adding secret Apple AirTag compartment to kids' sneakers — have we reached peak obsessive parenting? (NY Post) Audience Survey Complete our annual audience survey before August 31. Want to hear your company in the show? You too can reach the most influential leaders and operators in the industry. Here's our media kit. Contact us at cyberwire@n2k.com to request more info. The CyberWire is a production of N2K Networks, your source for strategic workforce intelligence. © N2K Networks, Inc. Learn more about your ad choices. Visit megaphone.fm/adchoices

Careers in Discovery
Martin Brenner, iBio

Careers in Discovery

Play Episode Listen Later Aug 6, 2025 55:22


This week on Careers in Discovery, we're joined by Martin Brenner, CEO and CSO of iBio and one of Biotech's most experienced R&D leaders. Martin shares his journey from pharmacologist to global R&D executive, with leadership roles at Pfenex, Recursion, AstraZeneca, and Stoke Therapeutics. Now at iBio, he leads a company developing gene therapies for rare diseases - while applying lessons from decades of drug development to a new generation of science. We talk about the power of simplicity in communication, why leaders need to create space for science to breathe, and how to build R&D teams that are lean, smart, and focused on what matters most.

LytePod
Buying Lights is Complicated - Justin Streeb

LytePod

Play Episode Listen Later Aug 5, 2025 59:57


The hardest part of buying lighting isn't the check - it's making sure you get what you ordered. In one of the most eye-opening conversations we've had, Justin Streeb, Co-Founder and CSO of 1 LUX, breaks down the behind-the-scenes chaos of actually buying lights. With over 20 years in the industry, Justin went from designing high-end homes in Aspen to founding multiple companies that now sit at the intersection of design, distribution, and strategy.This episode dives into why lighting procurement is so complicated, how the supply chain is fundamentally misaligned with design intent, and what it takes to build a business that truly serves both the specifier and the end client. Justin shares war stories from the 2008 recession, lessons from scaling up, and what still frustrates him about how our industry buys light.Wondering: “why is this so hard?”, This episode will shine a light on the answer.

On Strategy
Inside the judge's room for Favor Delivery's Gold Effie

On Strategy

Play Episode Listen Later Aug 3, 2025 39:09


Emily Portnoy, CSO at BBDO, NY, takes us inside this year's Effie judge's room to hear why Favor Delivery won Gold. We then hear from Favor's Chris Rogge and Preacher's Seher Sikandar for the story behind the winning campaign: "How Texas Orders In." You can see all the creative work on our website.

Breakfast Business
Visitor numbers to Ireland in June down by 2%

Breakfast Business

Play Episode Listen Later Aug 1, 2025 8:05


Visitor numbers from overseas to Ireland in June were down 2% to 654,000. That's much better than many had feared after earlier CSO data suggested a major fall-off in tourist numbers. But that figure is still around half the number of people who came to this island before Covid in 2019. Why? Is it the astonishingly high cost of holidaying and eating out in Ireland or is something else at play? Alice Mansergh chief executive of Tourism Ireland, joined Joe Lynam on the show to discuss.

The Disney Story Origins Podcast
CSO 20a – JAWS Part 1

The Disney Story Origins Podcast

Play Episode Listen Later Jul 31, 2025 74:48


Comparing and contrasting “JAWS” by Universal with the novel “JAWS” by Peter Benchley.  This podcast contains certain copyrighted works that were not specifically authorized to be used by the copyright holder(s), but which we believe in good faith are protected by federal law and the fair use doctrine (Section 107 of the Copyright Act). If you have […] The post CSO 20a – JAWS Part 1 first appeared on Cinema Story Origins Podcast.

SynGAP10 weekly 10 minute updates on SYNGAP1 (video)
Why join the Relutrigine study from Praxis for DEEs with motor seizures? - #S10e176

SynGAP10 weekly 10 minute updates on SYNGAP1 (video)

Play Episode Listen Later Jul 30, 2025 16:43


Wed July 30, 2025 Audience: Any family with a DEE who has a kid who has seizures, yes SYNGAP1 is a DEE and you are always my first audience.   See #S10e133 if you are curious about DEE vs other names. https://curesyngap1.org/podcasts/syngap10/what-is-this-syngap1-illness-disease-syndrome-ndd-dee-mrd5-nsid-actually-called-s10e133/   Action: If your kid has motor seizures, fill out the screener and join this amazing study. Link here: https://www.resiliencestudies.com/emerald   A motor seizure is a seizure where you can see something moving – including head drops, drops, convulsive, etc. – only excluded seizures are absence, myoclonia and infantile spasms.  You don't need to figure this out, just fill in the screener, let the doctors figure it out.   Questions: Come to live webinar tomorrow, it will not be recorded, so you have to come register here: https://curesyngap1.org/resources/webinars/webinar-111-introduction-to-praxiss-emerald-study-for-syngap1-patients/   TRIAL. Any DEE patient with 4 motor seizures a month, minimum. Age 2-65.  Adults are you listening? 24 weeks (6 months) weeks, placebo controlled but everyone will get drug at some point in the trial. 28 weeks (7 months) week OLE, with a chance for expanded access, so if it works, you can stay on. Fully decentralized, you don't have to go to a site if you don't want to. One US site open so far in Bethesda, there will be others.  Int'l sites in 2026.  US ENROLLING NOW. DRUG. Lots of science and big words in the links below, but here is what you need to know as a parent. It's a liquid, can go oral or in a g-tube. There is no ramp up, you put it in and it works.  In terms of speed, think Lorazepam not Lamotrigine. It's potent and specific, which means small volume.  Roughly 1ml for 10 kg.  This will be a rounding error in the face of a normal SynGAPian med regime. Even though this is a sodium channel drug, it should benefit all DEEs b/c, good to clarify tomorrow, all seizures end with a hyperactive sodium channel firing and that is what Relutragine focuses on.   PRAXIS. Serious people, lots of work on Epilepsy.  Connected to SYNGAP1 and DEEs, just need to move faster on SYNGAP1 ASO! CSO is Steve Petrou, works with SRF AUS and knows they are waiting. KD and AN started a company for SCN2A and it was absorbed by Praxis, they are still there and are relentless. Work on both small molecules and ASO, this is a way for them to see our team in action.   Cool links: AES 2024 Story. https://eppro01.ativ.me/web/page.php?page=session&project=AES24&id=2894147 Embold read out: https://www.neurologylive.com/view/relutrigine-shows-promise-phase-2-embold-study-scn2a-dee-scn8a-dee FDA Breakthrough. https://www.globenewswire.com/news-release/2025/07/17/3117145/0/en/Praxis-Precision-Medicines-Receives-FDA-Breakthrough-Therapy-Designation-for-Relutrigine-for-the-Treatment-of-Seizures-Associated-with-SCN2A-and-SCN8A-Developmental-and-Epileptic-E.html More links. https://delta.larvol.com/Products/?ProductId=05ccb036-a308-4249-abf6-e03b120839da   Why am I doing this? We need better meds and the way to meds is through trials. We need to jump at every trial, every time. 3. This one is decentralized, so minimum burden. If you get in now, this will be over before it's ASO trial time, so you could do both. Our Syngapians with motor seizures tend to be our most severe, we have to make sure we find out if this drug can help.  All our kids may progress to this point.   See you at the webinar, fill out the screener now: https://www.resiliencestudies.com/emerald

Perimenopause Simplified
73. Non-Hormonal Perimenopause Solutions: When HRT Isn't the Right Fit w/ Dr. Ana Duarte

Perimenopause Simplified

Play Episode Listen Later Jul 30, 2025 37:41


In this episode of Perimenopause Simplified, Claudia is joined by Dr. Ana Duarte, a medical doctor, expert in anti-aging and longevity medicine, and CSO of Eusari Nutrition. After 15+ years in pharmaceutical research, Ana hit her own perimenopause wall: burnt out, disconnected, and completely unprepared for the changes in her early 40s. That experience led her to pursue advanced training in women's health and longevity – and to discover just how overlooked midlife women are. No roadmap. No conversation. Just silence, shame, and guesswork. So she founded Eusari, a science-backed wellness brand built by and for women in perimenopause and menopause. Dr. Ana blends cutting-edge medical science with deep empathy, helping women feel like themselves again. She's also a speaker, writer, and passionate advocate for real, effective solutions to support women's health and vitality in midlife and beyond. Whether you can't take HRT or simply prefer not to, this episode is packed with evidence-based guidance to help you take back control of your health. You'll learn: Why some women can't or choose not to use hormone replacement therapy What non-hormonal alternatives women are turning to (and what actually works) The surprising science behind equol, a powerful ingredient for estrogen support What to look for in a trusted supplement brand How Dr. Ana's product, MenoPlay, supports mood, sleep, and energy without hormones How to cut through the noise and make informed choices in the age of overwhelm   Connect with Ana Duarte, MD: Instagram: @dr.anacd TikTok: @dr.anacd Facebook: facebook.com/eusariwellness LinkedIn: linkedin.com/in/anacatalinaduarte Website: www.eusari.com Free Resources: Midlife Guides   Links Mentioned: Ep. 45 Supplements for Perimenopause: What to Know Menoplay   Sources: Acupuncture In Menopause Cognitive Behavioral Therapy for MenopausePhytoestrogens for Hot Flashes     Not afraid of hormone therapy, but need some clarity? Grab Claudia's popular course: Perimenopause HRT Roadmap.   Save $100 until July 31st with coupon code: ROADMAP100. Claudia breaks down everything, so it's easy to understand and so you feel confident in advocating for the care you deserve.  Check it out here.      CONNECT WITH CLAUDIA:  Website YouTube Instagram Facebook   FREE RESOURCES:  Peri-What?! The Must-Have Guide for Women 40+ Navigating Hormone Changes Perimenopause Daily Checklist HRT 3-Day Crash Course   GET SUPPORT:  Perimenopause Clarity Session The Perimenopause Method Program Perimenopause HRT Roadmap Course   QUESTIONS?  Email: claudia@claudiapetrilli.com   LOVE THE SHOW? Please subscribe, leave a 5-star rating, review, and share, so that other women can find this podcast for guidance and support through perimenopause!   

RTÉ - News at One Podcast
Tourism numbers fall by 2% in June on last year - CSO

RTÉ - News at One Podcast

Play Episode Listen Later Jul 30, 2025 7:34


Sam Scriven, Senior Statistician with the CSO, talks to us about Tourism Figures

numbers tourism cso senior statistician
Unstoppable Mindset
Episode 356 – Unstoppable Pioneer in Web Accessibility with Mike Paciello

Unstoppable Mindset

Play Episode Listen Later Jul 25, 2025 62:53


In January, 2022 today's guest, Mike Paciello, made his first appearance on Unstoppable Mindset in Episode 19. It is not often that most of us have the opportunity and honor to meet a real trendsetter and pioneer much less for a second time. However, today, we get to spend more time with Mike, and we get to talk about not only the concepts around web accessibility, but we also discuss the whole concept of inclusion and how much progress we have made much less how much more work needs to be done.   Mike Paciello has been a fixture in the assistive technology world for some thirty years. I have known of him for most of that time, but our paths never crossed until September of 2021 when we worked together to help create some meetings and sessions around the topic of website accessibility in Washington D.C.   As you will hear, Mike began his career as a technical writer for Digital Equipment Corporation, an early leader in the computer manufacturing industry. I won't tell you Mike's story here. What I will say is that although Mike is fully sighted and thus does not use much of the technology blind and low vision persons use, he really gets it. He fully understands what Inclusion is all about and he has worked and continues to work to promote inclusion and access for all throughout the world. As Mike and I discuss, making technology more inclusive will not only help persons with disabilities be more involved in society, but people will discover that much of the technology we use can make everyone's life better. We talk about a lot of the technologies being used today to make websites more inclusive including the use of AI and how AI can and does enhance inclusion efforts.   It is no accident that this episode is being released now. This episode is being released on July 25 to coincide with the 35th anniversary of the signing of the Americans With Disabilities Act which was signed on July 26, 1990. HAPPY BIRTHDAY ADA!   After you experience our podcast with Mike, I'd love to hear your thoughts. Please feel free to email me at michaelhi@accessibe.com to tell me of your observations. Thanks.     About the Guest:   Mike Paciello is the Chief Accessibility Officer at AudioEye, Inc., a digital accessibility company. Prior to joining AudioEye, Mike founded WebABLE/WebABLE.TV, which delivers news about the disability and accessibility technology market. Mike authored the first book on web accessibility and usability, “Web Accessibility for People with Disabilities” and, in 1997, Mr. Paciello received recognition from President Bill Clinton for his work in the creation of World Wide Web Consortium's (W3C) Web Accessibility Initiative (WAI). He has served as an advisor to the US Access Board and other federal agencies since 1992.   Mike has served as an international leader, technologist, and authority in emerging technology, accessibility, usability, and electronic publishing. Mike is the former Founder of The Paciello Group (TPG), a world-renowned software accessibility consultancy acquired in 2017 by Vispero. Ways to connect with Mike:   mpaciello@webable.com Michael.paciello@audioeye.com Mikepaciello@gmail.com     About the Host:   Michael Hingson is a New York Times best-selling author, international lecturer, and Chief Vision Officer for accessiBe. Michael, blind since birth, survived the 9/11 attacks with the help of his guide dog Roselle. This story is the subject of his best-selling book, Thunder Dog.   Michael gives over 100 presentations around the world each year speaking to influential groups such as Exxon Mobile, AT&T, Federal Express, Scripps College, Rutgers University, Children's Hospital, and the American Red Cross just to name a few. He is Ambassador for the National Braille Literacy Campaign for the National Federation of the Blind and also serves as Ambassador for the American Humane Association's 2012 Hero Dog Awards.   https://michaelhingson.com https://www.facebook.com/michael.hingson.author.speaker/ https://twitter.com/mhingson https://www.youtube.com/user/mhingson https://www.linkedin.com/in/michaelhingson/   accessiBe Links https://accessibe.com/ https://www.youtube.com/c/accessiBe https://www.linkedin.com/company/accessibe/mycompany/ https://www.facebook.com/accessibe/       Thanks for listening!   Thanks so much for listening to our podcast! If you enjoyed this episode and think that others could benefit from listening, please share it using the social media buttons on this page. Do you have some feedback or questions about this episode? Leave a comment in the section below!   Subscribe to the podcast   If you would like to get automatic updates of new podcast episodes, you can subscribe to the podcast on Apple Podcasts or Stitcher. You can subscribe in your favorite podcast app. You can also support our podcast through our tip jar https://tips.pinecast.com/jar/unstoppable-mindset .   Leave us an Apple Podcasts review   Ratings and reviews from our listeners are extremely valuable to us and greatly appreciated. They help our podcast rank higher on Apple Podcasts, which exposes our show to more awesome listeners like you. If you have a minute, please leave an honest review on Apple Podcasts.       Transcription Notes:   Michael Hingson ** 00:00 Access Cast and accessiBe Initiative presents Unstoppable Mindset. The podcast where inclusion, diversity and the unexpected meet. Hi, I'm Michael Hingson, Chief Vision Officer for accessiBe and the author of the number one New York Times bestselling book, Thunder dog, the story of a blind man, his guide dog and the triumph of trust. Thanks for joining me on my podcast as we explore our own blinding fears of inclusion unacceptance and our resistance to change. We will discover the idea that no matter the situation, or the people we encounter, our own fears, and prejudices often are our strongest barriers to moving forward. The unstoppable mindset podcast is sponsored by accessiBe, that's a c c e s s i capital B e. Visit www.accessibe.com to learn how you can make your website accessible for persons with disabilities. And to help make the internet fully inclusive by the year 2025. Glad you dropped by we're happy to meet you and to have you here with us.   Michael Hingson ** 01:21 Well, hi everyone, and welcome to another episode of unstoppable mindset where inclusion diversity and the unexpected meet. Normally, our guests deal with the unexpected, which is anything that doesn't have to do with inclusion or diversity. Today, however, we get to sort of deal with both. We have a guest who actually was a guest on our podcast before he was in show 19 that goes all the way back to January of 2022, his name is Mike Paciello. He's been very involved in the whole internet and accessibility movement and so on for more than 30 years, and I think we're going to have a lot of fun chatting about what's going on in the world of accessibility and the Internet and and, you know, and but we won't probably get into whether God is a man or a woman, but that's okay, God is actually both, so we don't have to worry about that. But anyway, Mike, welcome to unstoppable mindset.   Mike Paciello ** 02:21 Yeah, Hey, Mike, thanks a lot. I can't believe has it really been already since today, six years since the last time I came on this? No, three, 320, 22 Oh, 2022, I for whatever I 2019 Okay, three years sounds a little bit more realistic, but still, it's been a long time. Thank you for having me. It's, it's, it's great to be here. And obviously, as you know, a lot of things have changed in my life since then. But, yeah, very   Michael Hingson ** 02:46 cool. Well, you were in show number 19. And I'm not sure what number this is going to be, but it's going to be above 360 so it's been a while. Amazing, amazing, unstoppable, unstoppable. That's it. We got to keep it going. And Mike and I have been involved in a few things together, in, in later, in, I guess it was in 20 when we do the M enabling Summit, that was 2021 wasn't it? Yeah, I think it was, I think it was the year before we did the podcast, yeah, podcast, 2021 right? So we were in DC, and we both worked because there was a group that wanted to completely condemn the kinds of technologies that accessibe and other companies use. Some people call it overlays. I'm not sure that that's totally accurate today, but we we worked to get them to not do what they originally intended to do, but rather to explore it in a little bit more detail, which I think was a lot more reasonable to do. So we've, we've had some fun over the years, and we see each other every so often, and here we are again today. So yeah, I'm glad you're here. Well, tell us a little about well, and I guess what we'll do is do some stuff that we did in 2022 tell us about kind of the early Mike, growing up and all that and what eventually got you into dealing with all this business of web accessibility and such. Yeah, thank you.   Mike Paciello ** 04:08 You know, I've tried to short this, shorten this story 100 times. Oh, don't worry. See if I get let's see if I can keep it succinct and and for the folks out there who understand verbosity and it's in its finest way for screen reader users, I'll try not to be verbose. I already am being   Michael Hingson ** 04:28 intermediate levels fine.   Mike Paciello ** 04:30 I came into this entire field as a technical writer trying to solve a problem that I kind of stumbled into doing some volunteer work for the debt the company that I then then worked for, a Digital Equipment Corporation, a software company, DEC software hardware company, back then, right back in the early 80s. And as a technical writer, I started learning at that time what was called Gen code. Eventually that morphed in. To what Goldfarb, Charles Goldfarb at IBM, called SGML, or standard, Generalized Markup Language, and that really became the predecessor, really gave birth to what we see on the web today, to HTML and the web markup languages. That's what they were, except back then, they were markup languages for print publications. So we're myself and a lot of colleagues and friends, people probably here, I'm sure, at bare minimum, recognized named George Kercher. George and I really paired together, worked together, ended up creating an international steer with a group of other colleagues and friends called the icad 22 which is 22 stands for the amount of elements in that markup language. And it became the adopted standard accessibility standard for the American Association of Publishers, and they published that became official. Eventually it morphed into what we today call, you know, accessible web development. It was the first instance by that was integrated into the HTML specification, I think officially, was HTML 3.1 3.2 somewhere in there when it was formally adopted and then announced in 1997 and at the World Wide Web Conference. That's really where my activity in the web began. So I was working at DEC, but I was doing a lot of volunteer work at MIT, which is where the W 3c was located at that particular time. And Tim Bursley, who a lot of people i Sir, I'm sure, know, the inventor of the web, led the effort at that time, and a few other folks that I work with, and.da Jim Miller, a few other folks. And we were, well, I wasn't specifically approached. Tim was approached by Vice President Gore and eventually President Clinton at that time to see if we could come up with some sort of technical standard for accessibility. And Tim asked if I'd like to work on it myself. Danielle, Jim, a few others, we did, and we came up that first initial specification and launched it as part of the Web Accessibility Initiative, which we created in 1997 from there, my career just took off. I went off did a couple of small companies that I launched, you know, my namesake company, the Paciello Group, or TPG, now called TPG IGI, yeah, yeah, which was acquired by vector capital, or this bureau back in 2017 so it's hard to believe that's already almost 10 years ago. No, yeah. And I've been walking in, working in the software, web accessibility field, usability field, writing fields, you know, for some pretty close to 45 years. It's 2025 40 years, I mean, and I started around 1984 I think it was 8384 when all this first   Michael Hingson ** 07:59 started. Wow, so clearly, you've been doing it for a while and understand a lot of the history of it. So how overall has the whole concept of web accessibility changed over the years, not only from a from a coding standpoint, but how do you think it's really changed when it comes to being addressed by the public and companies and so on.   Mike Paciello ** 08:26 That's a great question. I'd certainly like to be more proactive and more positive about it, but, but let me be fair, if you compare today and where web accessibility resides, you know, in the in the business value proposition, so to speak, and list the priorities of companies and corporations. You know, fortune 1000 fortune 5000 call whatever you whatever you want. Accessibility. Is there people? You could say section five way you could say the Web Accessibility Initiative, WCAG, compliance, and by and large, particularly technology driven, digital economy driven businesses, they know what it is. They don't know how to do it. Very rarely do they know how to do it. And even the ones that know how to do it don't really do it very well. So it kind of comes down to the 8020, rule, right? You're a business. Whatever kind of business you are, you're probably in more online presence than ever before, and so a lot of your digital properties will come under you know the laws that mandate usability and accessibility for people with disabilities today that having been said and more and more people know about it than ever before, certainly from the time that I started back in the you know, again, in the early, mid 80s, to where we are today. It's night and day. But in terms of prioritization, I don't know. I think what happens quite often is business value proposition. Decisions get in the way. Priorities get in the way of what a business in, what its core business are, what they're trying to accomplish, who they're trying to sell, sell to. They still view the disability market, never mind the blind and low vision, you know, market alone as a niche market. So they don't make the kind of investors that I, I believe that they could, you know, there's certainly, there are great companies like like Microsoft and and Google, Amazon, Apple, you know, a lot of these companies, you know, have done some Yeoman work at that level, but it's nowhere near where it should be. It just absolutely isn't. And so from that standpoint, in where I envision things, when I started this career was when I was in my 20 somethings, and now I'm over now I'm over 60. Well over 60. Yeah, I expected a lot more in, you know, in an internet age, much, much more.   Michael Hingson ** 11:00 Yeah, yeah. Well, it's it's really strange that so much has happened and yet so much hasn't happened. And I agree with you, there's been a lot of visibility for the concept of accessibility and inclusion and making the the internet a better place, but it is so unfortunate that most people don't know how to how to do anything with it. Schools aren't really teaching it. And more important than even teaching the coding, from from my perspective, looking at it more philosophically, what we don't tend to see are people really recognizing the value of disabilities, and the value that the market that people with disabilities bring to the to the world is significant. I mean, the Center for Disease Control talks about the fact that they're like up to 25% of all Americans have some sort of disability. Now I take a different approach. Actually. I don't know whether you've read my article on it, but I believe everyone on the in the in the world has a disability, and the reality is, most people are light dependent, but that's as much a disability as blindness. Except that since 1878 when Thomas Edison invented the light bulb. We have focused nothing short of trying to do everything we can to improve light on demand for the last 147 years. And so the disability is mostly covered up, but it's still there.   Mike Paciello ** 12:37 You know, yeah, and I did read that article, and I couldn't agree with you more. In fact, I personally think, and I actually have my own blog coming out, and probably later this month might be early, early July, where I talk about the fact that accessibility okay and technology really has been all along. And I love the fact that you call, you know, you identified the, you know, the late 1800s there, when Edison did the the light bulb, Alexander Graham Bell came up with, you know, the telephone. All of those adventures were coming about. But accessibility to people with disabilities, regardless of what their disability is, has always been a catalyst for innovation. That was actually supposed to be the last one I was going to make tonight. Now it's my first point because, because I think it is exactly as you said, Mike, I think that people are not aware. And when I say people, I mean the entire human population, I don't think that we are aware of the history of how, how, because of, I'm not sure if this is the best word, but accommodating users, accommodating people with disabilities, in whatever way, the science that goes behind that design architectural to the point of development and release, oftentimes, things that were done behalf of people with disabilities, or for People with disabilities, resulted in a fundamental, how's this for? For an interesting term, a fundamental alteration right to any other you know, common, and I apologize for the tech, tech, tech language, user interface, right, right? Anything that we interact with has been enhanced because of accessibility, because of people saying, hey, if we made this grip a little bit larger or stickier, we'll call it so I can hold on to it or softer for a person that's got fine motor dexterity disabilities, right? Or if we made a, you know, a web browser, which, of course, we have such that a blind individual, a low vision individual, can adjust the size of this, of the images and the fonts and things like that on a web page, they could do that unknown. Well, these things now. As we well know, help individuals without disabilities. Well, I'm not much, right, and I, again, I'm not speaking as a person beyond your characterization that, hey, look, we are all imperfect. We all have disabilities. And that is, that is absolutely true. But beyond that, I wear glasses. That's it. I do have a little hearing loss too. But you know, I'm finding myself more and more, for example, increasing the size of text. In fact, my note, yes, I increase them to, I don't know they're like, 18 point, just so that it's easier to see. But that is a common thing for every human being, just like you said.   Michael Hingson ** 15:36 Well, the reality is that so many tools that we use today come about. And came about because of people with disabilities. Peggy Chung Curtis Chung's wife, known as the blind history lady, and one of the stories that she told on her first visit to unstoppable mindset, which, by the way, is episode number five. I remember that Peggy tells the story of the invention of the typewriter, which was invented for a blind countist, because she wanted to be able to communicate with her lover without her husband knowing about it, and she didn't want to dictate things and so on. She wanted to be able to create a document and seal it, and that way it could be delivered to the lever directly. And the typewriter was the result of   Mike Paciello ** 16:20 that? I didn't know that. I will definitely go back. I just wrote it down. I wrote down a note that was episode number five, yeah, before with Curtis a couple of times, but obviously a good friend of ours, yeah, but I yeah, that's, that's, that's awesome.   Michael Hingson ** 16:37 Well, and look at, I'll tell you one of the things that really surprises me. So Apple was going to get sued because they weren't making any of their products accessible. And before the lawsuit was filed, they came along and they said, we'll fix it. And they did make and it all started to a degree with iTunes U but also was the iPhone and the iPod and so on. But they they, they did the work. Mostly. They embedded a screen reader called Voiceover in all of their operating systems. They did make iTunes you available. What really surprises me, though is that I don't tend to see perhaps some things that they could do to make voiceover more attractive to drivers so they don't have to look at the screen when a phone call comes in or whatever. And that they could be doing some things with VoiceOver to make it more usable for sighted people in a lot of instances. And I just don't, I don't see any emphasis on that, which is really surprising to me.   Mike Paciello ** 17:38 Yeah, I totally agree. I mean, there are a lot of use cases there that you go for. I think Mark Rico would certainly agree with you in terms of autonomous driving for the blind, right? Sure that too. But yeah, I definitely agree and, and I know the guy that the architect voiceover and develop voiceover for Apple and, boy, why can I think of his last name? I know his first name. First name is Mike. Is with Be My Eyes now and in doing things at that level. But I will just say one thing, not to correct you, but Apple had been in the accessibility business long before voice over Alan Brightman and Gary mulcher were instrumental towards convincing, you know, jobs of the importance of accessibility to people with disabilities,   Michael Hingson ** 18:31 right? But they weren't doing anything to make products accessible for blind people who needed screen readers until that lawsuit came along. Was   Mike Paciello ** 18:40 before screen readers? Yeah, that was before,   Michael Hingson ** 18:43 but they did it. Yeah. The only thing I wish Apple would do in that regard, that they haven't done yet, is Apple has mandates and requirements if you're going to put an app in the App Store. And I don't know whether it's quite still true, but it used to be that if your app had a desktop or it looked like a Windows desktop, they wouldn't accept it in the app store. And one of the things that surprises me is that they don't require that app developers make sure that their products are usable with with VoiceOver. And the reality is that's a it doesn't need to be a really significantly moving target. For example, let's say you have an app that is dealing with displaying star charts or maps. I can't see the map. I understand that, but at least voiceover ought to give me the ability to control what goes on the screen, so that I can have somebody describe it, and I don't have to spend 15 or 20 minutes describing my thought process, but rather, I can just move things around on the screen to get to where we need to go. And I wish Apple would do a little bit more in that regard.   Mike Paciello ** 19:52 Yeah, I think that's a great a great thought and a great challenge, if, between me and you. Yeah, I think it goes back to what I said before, even though we both see how accessibility or accommodating users with disabilities has led to some of the most incredible innovations. I mean, the Department of Defense, for years, would integrate people with disabilities in their user testing, they could better help, you know, military soldiers, things like that, assimilate situations where there was no hearing, there was they were immobile, they couldn't see all, you know, all of these things that were natural. You know, user environments or personas for people with disabilities. So they led to these kind of, you know, incredible innovations, I would tell you, Mike, I think you know this, it's because the business value proposition dictates otherwise.   Michael Hingson ** 20:55 Yeah, and, well, I guess I would change that slightly and say that people think that the business proposition does but it may very well be that they would find that there's a lot more value in doing it if they would really open up their minds to looking at it differently. It's   Mike Paciello ** 21:10 kind of, it's kind of like, it's tough. It's kind of like, if I could use this illustration, so to speak, for those who may not be religiously inclined, but you know, it's, it's like prophecy. Most people, you don't know whether or not prophecy is valid until years beyond, you know, years after. And then you could look back at time and say, See, it was all along. These things, you know, resulted in a, me, a major paradigm shift in the way that we do or don't do things. And I think that's exactly what you're saying. You know, if, if people would really look at the potential of what technologies like, you know, a voice over or, as you know, a good friend of mine said, Look, we it should be screen readers. It should be voice IO interfaces, right? That every human can use and interact with regardless. That's what we're really talking about. There's   Michael Hingson ** 22:10 a big discussion going on some of the lists now about the meta, Ray Ban, glasses, and some of the things that it doesn't do or that they don't do well, that they should like. It's really difficult to get the meta glasses to read completely a full page. I think there are ways that people have now found to get it to do that, but there are things like that that it that that don't happen. And again, I think it gets back to what you're saying is the attitude is, well, most people aren't going to need that. Well, the reality is, how do you know and how do you know what they'll need until you offer options. So one of my favorite stories is when I worked for Kurzweil a long time ago, some people called one day and they wanted to come and see a new talking computer terminal that that Ray and I and others developed, and they came up, and it turns out, they were with one of those initial organizations out of Langley, Virginia, the CIA. And what they wanted to do was to use the map the the terminal connected to their computers to allow them to move pointers on a map and not have to watch the map or the all of the map while they were doing it, but rather, the computer would verbalize where the pointer was, and then they could they could move it around and pin a spot without having to actually look at the screen, because the way their machine was designed, it was difficult to do that. You know, the reality is that most of the technologies that we need and that we use and can use could be used by so much, so many more people, if people would just really look at it and think about it, but, but you're right, they don't.   Mike Paciello ** 24:04 You know, it's, of course, raise a raise another good friend of mine. We both having in common. I work with him. I been down his office a few, more than few times, although his Boston office, anyway, I think he's, I'm not sure he's in Newton. He's in Newton. Yeah. Is he still in Newton? Okay. But anyway, it reminded me of something that happened in a similar vein, and that was several years ago. I was at a fast forward forward conference, future forward conference, and a company, EMC, who absorbed by Dell, I think, right, yes, where they all are. So there I was surprised that when that happened. But hey, yeah, yeah, I was surprised that compact bought depth, so that's okay, yeah, right. That HP bought count, right? That whole thing happened. But um, their chief science, chief scientist, I think he was a their CSO chief scientist, Doc. Came up and made this presentation. And basically the presentation was using voice recognition. They had been hired by the NSA. So it was a NSA right to use voice recognition in a way where they would recognize voices and then record those voices into it, out the output the transcript of that right text, text files, and feed them back to, you know, the NSA agents, right? So here's the funny part of that story goes up i i waited he gave his presentation. This is amazing technology, and what could it was like, 99% accurate in terms of not just recognizing American, English speaking people, but a number of different other languages, in dialects. And the guy who gave the presentation, I actually knew, because he had been a dec for many years. So in the Q and A Part I raised by hand. I got up there. He didn't recognize it a few years had gone by. And I said, you know, this is amazing technology. We could really use this in the field that I work in. And he said, Well, how's that? And I said, you know, voice recognition and outputting text would allow us to do now this is probably 2008 2009 somewhere in that area, would allow us to do real time, automated transcription for the Deaf, Captioning. And he looks at me and he he says, Do I know you? This is through a live audience. I said. I said, Yeah, Mark is it was. Mark said, So Mike gas yellow. He said, you're the only guy in town that I know that could turn a advanced, emerging technology into something for people with disabilities. I can't believe it. So that was, that was, but there was kind of the opposite. It was a technology they were focused on making this, you know, this technology available for, you know, government, obviously covert reasons that if they were using it and applying it in a good way for people with disabilities, man, we'd have been much faster, much further along or even today, right? I mean, it's being done, still not as good, not as good as that, as I saw. But that just goes to show you what, what commercial and government funding can do when it's applied properly?   Michael Hingson ** 27:41 Well, Dragon, naturally speaking, has certainly come a long way since the original Dragon Dictate. But there's still errors, there's still things, but it does get better, but I hear exactly what you're saying, and the reality is that we don't tend to think in broad enough strokes for a lot of the things that we do, which is so unfortunate,   Mike Paciello ** 28:03 yeah? I mean, I've had an old saying that I've walked around for a long time. I should have, I should make a baseball cap, whether something or T shirt. And it simply was, think accessibility, yeah, period. If, if, if we, organizations, people, designers, developers, architects, usability, people, QA, people. If everybody in the, you know, in the development life cycle was thinking about accessibility, or accessibility was integrated, when we say accessibility, we're talking about again, for users with disabilities, if that became part of, if not the functional catalyst, for technology. Man, we'd have been a lot further along in the quote, unquote value chains than we are today.   Michael Hingson ** 28:46 One of the big things at least, that Apple did do was they built voiceover into their operating system, so anybody who buys any Apple device today automatically has redundancy here, but access to accessibility, right? Which, which is really the way it ought to be. No offense to vispero and jaws, because they're they're able to fill the gap. But still, if Microsoft had truly devoted the time that they should have to narrate her at the beginning. We might see a different kind of an architecture today.   Mike Paciello ** 29:26 You know, I so I want to, by the way, the person that invented that wrote that code is Mike shabanik. That's his name I was thinking about. So Mike, if you're listening to this guy, just hi from two others. And if he's not, he should be, yeah, yeah, exactly right from two other mics. But so let me ask you this question, because I legitimately can't remember this, and have had a number of discussions with Mike about this. So VoiceOver is native to the US, right?   Michael Hingson ** 29:56 But no, well, no to to the to the to the. Products, but not just the US. No,   Mike Paciello ** 30:02 no, I said, OS, yes, it's native to OS, yeah, right. It's native that way, right? But doesn't it still use an off screen model for producing or, you know, translate the transformation of, you know, on screen to voice.   Michael Hingson ** 30:27 I'm not sure that's totally true. Go a little bit deeper into that for me.   Mike Paciello ** 30:34 Well, I mean, so NVDA and jaws use this off screen model, right, which is functionally, they grab, will they grab some content, or whatever it is, push it to this, you know, little black box, do all those translations, you know, do all the transformation, and then push it back so it's renderable to a screen reader. Okay, so that's this off screen model that is transparent to the users, although now you know you can get into it and and tweak it and work with it right, right? I recall when Mike was working on the original design of of nary, excuse me, a voiceover, and he had called me, and I said, Are you going to continue with the notion of an off screen model? And he said, Yeah, we are. And I said, Well, when you can build something that's more like what TV Raman has built into Emacs, and it works integral to the actual OS, purely native. Call me because then I'm interested in, but now that was, you know, 1520, years ago, right? I mean, how long has voiceover been around,   Michael Hingson ** 31:51 since 2007   Mike Paciello ** 31:54 right? So, yeah, 20 years ago, right? Just shy of 20 years, 18 years. So I don't know. I honestly don't know. I'm   Michael Hingson ** 32:02 not totally sure, but I believe that it is, but I can, you know, we'll have to, we'll have to look into that.   Mike Paciello ** 32:08 If anyone in the audience is out there looking at you, get to us before we find out. Let us we'll find out at the NFB   Michael Hingson ** 32:12 convention, because they're going to be a number of Apple people there. We can certainly ask, there   Mike Paciello ** 32:17 you go. That's right, for sure. James Craig is bound to be there. I can ask him and talk to him about that for sure. Yep, so anyway,   Michael Hingson ** 32:23 but I think, I think it's a very it's a valid point. And you know, the the issue is that, again, if done right and app developers are doing things right there, there needs to, there ought to be a way that every app has some level of accessibility that makes it more available. And the reality is, people, other than blind people use some of these technologies as well. So we're talking about voice input. You know, quadriplegics, for example, who can't operate a keyboard will use or a mouse can use, like a puff and zip stick to and and Dragon to interact with a computer and are successful at doing it. The reality is, there's a whole lot more opportunities out there than people think. Don't   Mike Paciello ** 33:11 I agree with that. I'm shaking my head up and down Mike and I'm telling you, there is, I mean, voice recognition alone. I can remember having a conversation with Tony vitality, one of the CO inventors of the deck talk. And that goes all the way back into the, you know, into the early 90s, about voice recognition and linguistics and what you know, and I know Kurzweil did a lot of working with Terry right on voice utterances and things like that. Yeah, yeah. There's, there's a wide open window of opportunity there for study and research that could easily be improved. And as you said, and this is the point, it doesn't just improve the lives of the blind or low vision. It improves the lives of a number of different types of Persona, disability persona types, but it would certainly create a pathway, a very wide path, for individuals, users without disabilities, in a number of different life scenarios.   Michael Hingson ** 34:10 Yeah, and it's amazing how little sometimes that's done. I had the pleasure a few years ago of driving a Tesla down Interstate 15 out here in California. Glad I wasn't there. You bigot, you know, the co pilot system worked. Yeah, you know, I just kept my hands on the wheel so I didn't very much, right? Not have any accidents. Back off now it worked out really well, but, but here's what's really interesting in that same vehicle, and it's something that that I find all too often is is the case if I were a passenger sitting in the front seat, there's so much that I as a passenger don't have access to that other passenger. Do radios now are mostly touchscreen right, which means and they don't build in the features that would make the touchscreen system, which they could do, accessible. The Tesla vehicle is incredibly inaccessible. And there's for a guy who's so innovative, there's no reason for that to be that way. And again, I submit that if they truly make the product so a blind person could use it. Think of how much more a sighted person who doesn't have to take their eyes off the road could use the same technologies.   Mike Paciello ** 35:35 You know, Mike, again, you and I are on the same page. I mean, imagine these guys are supposed to be creative and imaginative and forward thinking, right? Could you? Can you imagine a better tagline than something along the lines of Tesla, so user friendly that a blind person can drive it? Yeah? I mean this is, have you heard or seen, you know, metaphorically speaking, or that's okay, a an advertisement or PR done by any, any company, because they're all, all the way across the board, that hasn't featured what it can do to enhance lives of people with disabilities. Where it wasn't a hit. I mean, literally, it was, yeah, you see these commercials played over and over to Apple, Microsoft, Emma, I see McDonald's, Walmart. I mean, I could just name, name the one after another. Really, really outstanding. Salesforce has done it. Just incredible. They would do it, yeah. I mean, there is there any more human centric message than saying, Look what we've built and designed we're releasing to the masses and everyone, anyone, regardless of ability, can use it. Yeah, that, to me, is that's, I agree that's a good route, right for marketing and PR, good,   Michael Hingson ** 37:03 yeah. And yet they don't, you know, I see commercials like about one of the one of the eye injections, or whatever Bobby is, Mo or whatever it is. And at the beginning, the woman says, I think I'm losing sight of the world around me. You know that's all about, right? It's eyesight and nothing else. And I appreciate, I'm all for people keeping their eyesight and doing what's necessary. But unfortunately, all too often, we do that at the detriment of of other people, which is so unfortunate.   Mike Paciello ** 37:39 Yeah, you know again, not to, not to get off the subject, but one of my favorite books is rethinking competitive advantage, by Ram Sharon. I don't know if you know know him, but the guy is one of my heroes in terms of just vision and Business and Technology. And in this, this book, he wrote this a couple of years ago. He said this one this is his first rule of competition in the digital age. The number one rule was simply this, a personalized consumer experience, key to exponential growth. That's exactly you and I are talking about personally. I want to see interfaces adapt to users, rather than what we have today, which is users having to adapt to the interface.   Michael Hingson ** 38:32 Yeah, and it would make so much sense to do so. I hope somebody out there is listening and will maybe take some of this to heart, because if they do it right, they can have a huge market in no time at all, just because they show they care. You know, Nielsen Company did a survey back in 2016 where they looked at a variety of companies and consumers and so on. And if I recall the numbers right, they decided that people with disabilities are 35% more likely to continue to work with and shop, for example, at companies that really do what they can to make their websites and access to their products accessible, as opposed to not. And that's that's telling. It's so very telling. But we don't see people talking about that nearly like we should   Mike Paciello ** 39:20 you talk about a business value proposition. There is bullet proof that where you are leaving money on the table, yep, and a lot of it, yeah, exactly. We're not talking about 1000s or hundreds of 1000s. We're talking about billions and trillions, in some instances, not an exaggeration by any stretch of the imagination, very, very simple math. I had this conversation a couple years ago with the CEO of Pearson. At that time, he's retired, but, you know, I told him, if you spent $1 for every person that it was in the world with. Disability, you're, you're, you're talking about 1/4 of the population, right? It's simple math, simple math,   Michael Hingson ** 40:08 but people still won't do it. I mean, we taught you to mention section 508, before with the whole issue of web access, how much of the government has really made their websites accessible, even though it's the law?   Mike Paciello ** 40:19 Yeah, three years, three or four years ago, they did a study, and they found out that the good that every federal agency, most of the federal agencies, were not even keeping up thinking with reporting of the status, of where they were, and yet that was written right into the five way law. They were mandated to do it, and they still did do   Michael Hingson ** 40:37 it. We haven't, you know, the whole Americans with Disabilities Act. Finally, the Department of Justice said that the internet is a place of business, but still, it's not written in the law. And of course, we only see about 3% of all websites that tend to have any level of access. And there's no reason for that. It's not that magical. And again, I go back to what do we do to get schools and those who teach people how to code to understand the value of putting in accessibility right from the outset?   Mike Paciello ** 41:10 Yeah, no, I totally agree with you. I think this is what Kate sanka is trying to do with with Teach access. In fact, you know, again, my company, TPG was one of the founding companies have teach access back again, 10 years ago, when it first started. But that's where it starts. I mean, they're, they're pretty much focused on post secondary, university education, but I could tell you on a personal level, I was speaking at my kids grade school, elementary school, because they were already using laptops and computers back then it starts. Then you've got to build a mindset. You've got to build it we you've heard about the accessibility, maturity models coming out of the W, 3c, and in I, double AP. What that speaks to fundamentally, is building a culture within your corporate organization that is think accessibility as a think accessibility mindset, that it is woven into the fiber of every business line, in every technology, software development life cycle, all of the contributors at that level, from A to Z. But if you don't build it into the culture, it's not going to happen. So I would love to see a lot more being done at that level. But yeah, it's, it's, it's a, it's a hero. Yeah,   Michael Hingson ** 42:34 we're, we're left out of the conversation so much. Yeah, yeah, totally. So you, you sold TPG, and you then formed, or you had web able and then able Docs.   Mike Paciello ** 42:48 So what web able came out was a carve out, one of two carve outs that I had from when I sold TPG. The other was open access technologies, which which eventually was sold to another accessibility company primarily focused on making documentation accessible to meet the WCAG and other standards requirements and web able I carved out. It's been a kind of a hobby of mine now, for since I sold TPG, I'm still working on the back end, ironically, from the get go, so we're talking, you know, again, eight years ago, I had built machine learning and AI into it. From then back then, I did so that what it does is it very simply, goes out and collects 1000s and 1000s of articles as it relates to technology, people with disabilities, and then cleans them up and post them to web able.com I've got a lot more playing for it, but that's in a nutshell. That's what it does. And I don't we do some we do some QA review to make sure that the cleanup in terms of accessibility and the articles are are properly formatted and are accessible. We use the web aim API, but yeah, works like magic. Works like clockwork, and that's got aI uses IBM Watson AI built into it. Yeah, enable docs was abledocs was, how should I say this in a nice way, abledocs was a slight excursion off of my main route. It can work out. I wish it had. It had a lot of potential, much like open access technologies, but they both suffered from owners who really, really not including myself, who just didn't have good vision and in lack humility,   Michael Hingson ** 44:43 yeah. How's that? There you go. Well, so not to go political or anything, but AI in general is interesting, and I know that there have been a lot of debates over the last few years about artificial. Intelligence and helping to make websites accessible. There are several companies like AudioEye, user way, accessibe and so on that to one degree or another, use AI. What? What? So in general, what do you think about AI and how it's going to help deal with or not, the whole issue of disabilities and web access,   Mike Paciello ** 45:22 yeah, and we're going to set aside Neil Jacobs thoughts on how he sees it in the future, right? Although I have to tell you, he gave me some things to think about, so we'll just set that to to the side. So I think what AI offers today is something that I thought right away when it started to see the, you know, the accessibes, the user ways, the audio, eyes, and all the other companies kind of delving into it, I always saw potential to how's this remediate a fundamental problem or challenge, let's not call it a problem, a challenge that we were otherwise seeing in the professional services side of that equation around web accessibility, right? So you get experts who use validation tools and other tools, who know about code. Could go in and they know and they use usability, they use user testing, and they go in and they can tell you what you need to do to make your digital properties right, usable and accessible. People with disabilities, all well and good. That's great. And believe me, I had some of the best people, if not the best people in the world, work for me at one time. However, there are a couple of things it could not do in it's never going to do. Number one, first and foremost, from my perspective, it can't scale. It cannot scale. You can do some things at, you know, in a large way. For example, if, if a company is using some sort of, you know, CMS content management system in which their entire sites, you know, all their sites, all their digital properties, you know, are woven into templates, and those templates are remediated. So that cuts down a little bit on the work. But if you go into companies now, it's not like they're limited to two or three templates. Now they've got, you know, department upon department upon department, everybody's got a different template. So even those are becoming very vos, very verbose and very plentiful. So accessibility as a manual effort doesn't really scale well. And if it does, even if it could, it's not fast enough, right? So that's what AI does, AI, coupled with automation, speeds up that process and delivers a much wider enterprise level solution. Now again, AI automation is not, is not a whole, is not a holistic science. You know, it's not a silver bullet. David Marathi likes to use the term, what is he? He likes the gold standard. Well, from his perspective, and by the way, David Marathi is CEO of audio. Eye is a combination of automation AI in expert analysis, along with the use of the integration of user testing and by user testing, it's not just personas, but it's also compatibility with the assistive technologies that people with disabilities use. Now, when you do that, you've got something that you could pattern after a standard software development life cycle, environment in which you integrate all of these things. So if you got a tool, you integrate it there. If you've got, you know, a digital accessibility platform which does all this automation, AI, right, which, again, this is the this is a forester foresters take on the the the daps, as they calls it. And not really crazy about that, but that's what they are. Digital Accessibility platforms. It allows us to scale and scale at costs that are much lower, at speeds that are much faster, and it's just a matter of like any QA, you've got to check your work, and you've got it, you can't count on that automation being absolute. We know for a fact that right now, at best, we're going to be able to get 35 to 40% accuracy, some claim, larger different areas. I'm still not convinced of that, but the fact of the matter is, it's like anything else. Technology gets better as it goes, and we'll see improvements over time periods.   Michael Hingson ** 49:49 So here's here's my thought, yeah, let's say you use AI in one of the products that's out there. And I. You go to a website and you include it, and it reasonably well makes the website 50% more usable and accessible than it was before. I'm just, I just threw out that number. I know it's random. Go ahead, Yep, yeah, but let's say it does that. The reality is that means that it's 50% that the web developers, the web coders, don't have to do because something else is dealing with it. But unfortunately, their mentality is not to want to deal with that because they also fear it. But, you know, I remember back in the mid 1980s I started a company because I went off and tried to find a job and couldn't find one. So I started a company with a couple of other people, where we sold early PC based CAD systems to architects, right? And we had AutoCAD versus CAD. Another one called point line, which was a three dimensional system using a y cap solid modeling board that took up two slots in your PC. So it didn't work with all PCs because we didn't have enough slots. But anyway, right, right, right. But anyway, when I brought architects in and we talked about what it did and we showed them, many of them said, I'll never use that. And I said, why? Well, it does work, and that's not the question. But the issue is, we charge by the time, and so we take months to sometimes create designs and projects, right? And so we can't lose that revenue. I said, you're looking at it all wrong. Think about it this way, somebody gives you a job, you come back and you put it in the CAD system. You go through all the iterations it takes, let's just say, two weeks. Then you call your customer in. You use point line, and you can do a three dimensional walk through and fly through. You can even let them look out the window and see what there is and all that they want to make changes. They tell you the changes. You go off and you make the changes. And two weeks later, now it's a month, you give them their finished product, all the designs, all the plots and all that, all done, and you charge them exactly the same price you were going to charge them before. Now you're not charging for your time, you're charging for your expertise, right? And I think that same model still holds true that the technology, I think most people will agree that it is not perfect, but there are a lot of things that it can do. Because the reality is, the Web Content Accessibility Guidelines, are all things that can be defined with computer code, whether it necessarily does it all well with AI or not, is another story. But if it does it to a decent fraction, it makes all the difference in terms of what you're able to do and how quickly you can do   Mike Paciello ** 52:52 it. Yeah, I can argue with that at all. I think any time that we can make our jobs a little bit easier so that we can focus where we should be focused. In this case, as you said, the expertise side of it, right to fix those complicated scenarios or situations that require a hands on surgical like Right? Expertise, you can do that now. You've got more hours more time because it's been saved. The only thing I would say, Mike, about what, what you just said, is that there with that, with that mindset, okay, comes responsibility. Oh, yeah, in this is where I think in everybody that knows anything about this environment, you and I have an intimate understanding of this. The whole overlay discussion is the biggest problem with what happened was less about the technology and more about what claims are being made. Yeah, the technology could do which you could not do in, in some cases, could never do, or would never, would never do, well, right? So if you create, and I would submit this is true in as a fundamental principle, if you create a technology of any kind, you must, in truth, inform your clients of of what it can and cannot do so they understand the absolute value to them, because the last thing you want, because, again, we live in a, unfortunately, a very litigious world. Right soon as there's   Michael Hingson ** 54:49 a mistake couldn't happen,   Mike Paciello ** 54:51 they'll go right after you. So now you know, and again, I don't I'm not necessarily just blaming the ambulance chasers of the world. World. I was talking to an NFP lawyer today. He referred to them in a different name, and I can't remember well, I never heard the expression before, but that's what he meant, right? Yeah, it's the salesman and the product managers and the marketing people themselves, who are were not themselves, to your point, properly trained, properly educated, right? It can't be done, what clearly could not be said, what should or should not be said, right? And then you got lawyers writing things all over the place. So, yeah, yeah. So, so I look people knew when I made the decision to come to audio eye that it was a make or break scenario for me, or at least that's what they thought in my mindset. It always, has always been, that I see incredible possibilities as you do or technology, it just has to be handled responsibly.   Michael Hingson ** 55:56 Do you think that the companies are getting better and smarter about what they portray about their products than they than they were three and four and five years ago.   Mike Paciello ** 56:08 Okay, look, I sat in and chaired a meeting with the NFB on this whole thing. And without a doubt, they're getting smarter. But it took not just a stick, you know, but, but these large lawsuits to get them to change their thinking, to see, you know, where they where they were wrong, and, yeah, things are much better. There's still some issues out there. I both know it that's going to happen, that happens in every industry,   Michael Hingson ** 56:42 but there are improvements. It is getting better, and people are getting smarter, and that's where an organization like the NFB really does need to become more involved than in a sense, they are. They took some pretty drastic steps with some of the companies, and I think that they cut off their nose, despite their face as well, and that didn't help. So I think there are things that need to be done all the way around, but I do see that progress is being made too. I totally   Mike Paciello ** 57:11 agree, and in fact, I'm working with them right now. We're going to start working on the California Accessibility Act again. I'm really looking forward to working with the NFB, the DRC and Imperato over there and his team in the disability rights consortium, consortium with disability rights. What DRC coalition, coalition in in California. I can't wait to do that. We tried last year. We got stopped short. It got tabled, but I feel very good about where we're going this year. So that's, that's my that's, that is my focus right now. And I'm glad I'm going to be able to work with the NFB to be able to do that. Yeah, well, I, I really do hope that it passes. We've seen other states. We've seen some states pass some good legislation, and hopefully we will continue to see some of that go on. Yeah, Colorado has done a great job. Colorado sent a great job. I think they've done it. I really like what's being done with the EAA, even though it's in Europe, and some of the things that are going there, Susanna, Lauren and I had some great discussions. I think she is has been a leader of a Yeoman effort at that level. So we'll see. Let's, let's, I mean, there's still time out here. I guess I really would like to retire,   Michael Hingson ** 58:28 but I know the feeling well, but I can't afford to yet, so I'll just keep speaking and all that well, Mike, this has been wonderful. I really appreciate you taking an hour and coming on, and at least neither of us is putting up with any kind of snow right now, but later in the year we'll see more of that.   Mike Paciello ** 58:45 Yeah, well, maybe you will. We don't get snow down. I have. We've gotten maybe 25 flakes in North Carolina since I've been here.   Michael Hingson ** 58:53 Yeah, you don't get a lot of snow. We don't hear we don't really get it here, around us, up in the mountains, the ski resorts get it, but I'm out in a valley, so we don't, yeah,   Mike Paciello ** 59:02 yeah, no. I love it. I love this is golfing weather.   Michael Hingson ** 59:05 There you go. If people want to reach out to you, how do they do that?   Mike Paciello ** 59:11 There's a couple of ways. Certainly get in touch with me at AudioEye. It's michael.paciello@audioeye.com   Michael Hingson ** 59:17 B, A, C, I, E, L, L, O,   Mike Paciello ** 59:18 that's correct. Thank you for that. You could send me personal email at Mike paciello@gmail.com and or you can send me email at web able. It's m passielo at web able.com, any one of those ways. And please feel free you get on all the social networks. So feel free to link, connect to me. Anyway, I try to respond. I don't think there's anyone I I've not responded to one form or another.   Michael Hingson ** 59:46 Yeah, I'm I'm the same way. If I get an email, I want to respond to it. Yeah, well, thanks again for being here, and I want to thank all of you for listening. We really appreciate it. Love to hear your thoughts about this episode. Please feel free to email. Me, you can get me the email address I generally use is Michael h i at accessibe, A, C, C, E, S, S, i, b, e.com, or you can go to our podcast page, which is Michael hingson.com/podcast, and there's a contact form there. But love to hear from you. Love to hear your thoughts, and most of all, please give us a five star rating wherever you're listening. We value your ratings and your reviews a whole lot, so we really appreciate you doing that. And if any of you, and Mike, including you, can think of other people that you think ought to be guests on the podcast, we are always looking for more people, so fill us up, help us find more folks. And we would appreciate that a great deal. So again, Mike, thanks very much. This has been a lot of fun, and we'll have to do it again.   Mike Paciello ** 1:00:44 Thanks for the invitation. Mike, I really appreciate it. Don't forget to add 10 Nakata to your list,   Michael Hingson ** 1:00:49 You have been listening to the Unstoppable Mindset podcast. Thanks for dropping by. I hope that you'll join us again next week, and in future weeks for upcoming episodes. To subscribe to our podcast and to learn about upcoming episodes, please visit www dot Michael hingson.com slash podcast. Michael Hingson is spelled m i c h a e l h i n g s o n. While you're on the site., please use the form there to recommend people who we ought to interview in upcoming editions of the show. And also, we ask you and urge you to invite your friends to join us in the future. If you know of any one or any organization needing a speaker for an event, please email me at speaker at Michael hingson.com. I appreciate it very much. To learn more about the concept of blinded by fear, please visit www dot Michael hingson.com forward slash blinded by fear and while you're there, feel free to pick up a copy of my free eBook entitled blinded by fear. The unstoppable mindset podcast is provided by access cast an initiative of accessiBe and is sponsored by accessiBe. Please visit www.accessibe.com . AccessiBe is spelled a c c e s s i b e. There you can learn all about how you can make your website inclusive for all persons with disabilities and how you can help make the internet fully inclusive by 2025. Thanks again for Listening. Please come back and visit us again next week.

Home and Away - A Sporting KC Podcast
Episode 146 - SKC get a point from their last two games, Zavagnin continues making necessary halftime adjustments, and more questions than answers about the future.

Home and Away - A Sporting KC Podcast

Play Episode Listen Later Jul 24, 2025 94:43


Sporting KC went behind early in both games since the last episode, in what is becoming a worrying trend in home matches this year. They did show fight in both matches, performing much better in the 2nd half of each, which is also becoming a noteworthy trend of late.The roster has limitations, and interim coach Kerry Zavagnin is making due as best he can with the players he has at his disposal, along with making aggressive changes when things aren't working. That said, the team continues to appear to have significant limitations in influencing game state on their own, rather reacting to it, but also taking advantage when it goes in their favor.The summer transfer window is about to open and we discuss what is reasonable to expect from this window both in SKC's available flexibility but also the potential for significant change given that there is still no CSO in place to drive the strategy of the team.Finally, a quick discussion about MLS All Star, Miami figuring out how to manipulate the rulebook to sign Rodrigo de Paul, and a quick preview of SKC's upcoming visit to Vancouver.Music by The Spin Wires

Deciphered: The Fintech Podcast
Stablecoins: State of the Union 2025

Deciphered: The Fintech Podcast

Play Episode Listen Later Jul 22, 2025 46:13


In this episode of Deciphered, Mike Cashman, partner, Bain & Company is joined by Ricardo Correia, partner, Bain & Company, Dante Disparte, CSO and Head of Global Policy and Operations, Circle, Jane McEvoy, SVP Fintech, BVNK and Cindy Turner, Chief Product Officer, WorldPay to discuss the state of stablecoins in 2025.Timestamps:03:22 Stablecoin infrastructure providers and enterprise integration04:53 WorldPay's stablecoin payout solutions for marketplaces06:11 Stablecoins disrupting traditional cross-border payments10:00 Singleness of money and stablecoin interoperability14:40 Elasticity of money and stablecoin reserves17:41 Productization of stablecoins in payouts and escrow27:03 Regulatory harmonization for stablecoins across jurisdictions31:27 Future use cases of stablecoins beyond cross-border paymentsPlease subscribe to the show so you never miss an episode, and leave us a review if you enjoy the show!You can find Mike Cashman hereYou can find Ricardo Correia hereYou can find Dante Disparte hereYou can find Jane McEvoy hereYou can find Cindy Turner hereFor more insights from the Deciphered podcast, visit the page on Bain's website

BioSpace
Why Countries Are Racing to Build mRNA Factories While America Hesitates on Next-Gen Vaccines

BioSpace

Play Episode Listen Later Jul 22, 2025 15:19


This episode continues the discussion regarding the rapid evolution of mRNA technologies since COVID-19. Guests discuss the improvements that have occurred within just a few years, which are making these therapies more reliable, cost-effective and viable for personalized cancer, rare disease chronic disease treatment.Today's episode is sponsored by Eclipsebio. From AI-ready datasets to sequencing validation, they drive RNA success.Explore their solutions at ⁠https://eclipsebio.com/⁠.Host⁠⁠⁠⁠⁠⁠Lori Ellis⁠⁠⁠⁠⁠⁠, Head of Insights, BioSpaceGuests⁠Andy Geall⁠, Co-founder and Chief Development Officer, Replicate Bioscience; Chair of the Board, Alliance for mRNA Medicines⁠Pad Chivukula⁠, Co-founder, CSO & COO, Arcturus TherapeuticsDisclaimer: The views expressed in this discussion by guests are their own and do not represent those of their organizations.

Medical Spa Insider
Authenticity, Strategy and Storytelling in Aesthetic Marketing

Medical Spa Insider

Play Episode Listen Later Jul 16, 2025 42:06


This week, AmSpa founder and CEO Alex R. Thiersch, JD, sits down with Chris Suchánek, founder and CSO of Firm Media and creator of Ailm Atelier, a new online platform showcasing aesthetic doctors and their stories. They talk about Chris's journey from the music business to specialty medical marketing, and how authenticity, storytelling, and innovation are reshaping how med spas and aesthetic practices connect with patients. How he transitioned from Grammy-winning music marketing to aesthetic advertising; The origin and mission of Ailm Atelier as a platform for storytelling and recognition; Why authenticity and patient trust are the new currency in aesthetic branding; The nomination-only process for Ailm's featured top aesthetic doctors; How he redefined his personal brand with inspiration from a 90s billboard campaign; A mixed media marketing approach to target med spa patients in their homes; The future of Ailm as a consumer-facing, digital platform. — Music by Ghost Score

Trust Issues
EP 11 - AI, identity, and the calm before the breach

Trust Issues

Play Episode Listen Later Jul 15, 2025 46:14


What does it take to stay calm in the face of constant cyber pressure—and why does that mindset matter more than ever? In this episode of Security Matters, host David Puner speaks with Den Jones, founder and CEO of 909Cyber, about his transition from enterprise chief security officer (CSO) to cybersecurity consultant. They explore what it means to lead with clarity and composure in a high-stakes environment, the realities of launching a firm in a crowded market, and how pragmatic security strategies—especially around identity, AI, and Zero Trust—can help organizations navigate AI-driven threats, talent shortages, and operational complexity. It's a candid conversation about what works and what doesn't when it comes to modern security leadership.

The Fearless Mindset
Episode 257 - The New Rules of Security: Threats, Tech, and How to Stay Ahead

The Fearless Mindset

Play Episode Listen Later Jul 15, 2025 32:44


In this episode, Mark Ledlow is joined by Benjamin Whitfield, a seasoned security professional with a military and agency background and a former CIA. They discuss Ben's transition from being an executive in Silicon Valley to an independent consultant, and delve into the complexities of the security industry. Key topics include the role of Chief Security Officers, the importance of sales in security, and the need for risk-based assessment. They also explore emerging trends in security, the impact of the new administration, and the importance of continuing education for security professionals.Learn about all this and more in this episode of The Fearless Mindset Podcast.KEY TAKEAWAYSBuilding relationships is crucial for ensuring security programs are funded and supported. The role of a Chief Security Officer (CSO) involves significant political and sales skills. Proper risk assessments tailored to the company culture are essential for effective security programs. The executive protection industry's future might see growth due to increasing threats and new economic sectors like cryptocurrency. Ongoing education and adaptation to emerging trends and technologies are vital for security professionals.QUOTES"It's all sales... Your job really is to advocate for how do you protect people, facilities, operations as much as possible given what the political climate is in your company." "If you build a program that meets the absolute corporate need, your job isn't going away." "In Silicon Valley, I'll stereotype. I'm just the kid wearing the hoodie. You're the kid wearing the hoodie who's now worth, you know, a billion dollars." "There are multiple ways where a company can provide, can have security for its senior most executives." "The CSO chair is, you're playing politics, you're fighting for budget with everybody else."Get to know more about Benjamin Whitfield through the links below.https://www.linkedin.com/in/benjaminwhitfield/To hear more episodes of The Fearless Mindset podcast, you can go to https://the-fearless-mindset.simplecast.com/ or listen to major podcasting platforms such as Apple, Google Podcasts, Spotify, etc. You can also subscribe to the Fearless Mindset YouTube Channel to watch episodes on video.

BYO Nano Brew Podcast
Episode 67: Improving your Beer Quality

BYO Nano Brew Podcast

Play Episode Listen Later Jul 15, 2025 59:20


Sensory analysis, setting up a lab for QC tests, and understanding your raw ingredients are all paramount when it comes to improving the quality of your beer. We talk with two experts - Lindsay Barr and Ashton Lewis - who are here to help you level up beer quality in a small-scale brewery.Guests:Lindsay Barr is the CSO and Founding Partner of DraughtLab Sensory Software where she helps food & beverage companies use tasting technology to make products that people love.  After earning a Masters in Food Science from UC Davis, she began her career at New Belgium Brewing Company managing the Sensory and Consumer Research program. Along with her work at DraughtLab, she teaches Sensory for the Master Brewers course at UC Davis and the Siebel Institute and judges global beer competitions. During her career, she has published numerous groundbreaking techniques to lower the barrier-to-entry into sensory science and continues to be passionate about making sensory accessible for all businesses. She currently lives in San Francisco and can be found running or lounging in Golden Gate Park, sailing, or playing around in the Castro.For the last 29 years Ashton Lewis has worked for Brew Your Own Magazine as technical editor and “Help Me, Mr. Wizard” columnist.  His day job since December 2016 has been with RahrBSG where he is currently Manager of Training and Technical Support.  Prior to working in the world of ingredients, Ashton was the Staff Master Brewer and Brewing Group Sales Manager for the Paul Mueller Company living in the world of custom stainless steel.  He was also a partner in the Springfield Brewing Company (SBC) in Springfield, Missouri, and SBC's master brewer from 1997 to 2019.  Ashton holds a B.S. in Food Science from Virginia Tech (1991) and a M.S. in Food/Brewing Science from UC Davis (1994), and is currently the MBAA District Great Plains Technical Chair.  In his spare time, he enjoys music, cooking, homebrewing, talking about beer, and playing with Excel. The BYO Nano Podcast Episode 67  is sponsored by:Five Star ChemicalsLooking for a powerful, no-rinse sanitizer that gets the job done fast? Meet Saniclean PAA Pro from Five Star Chemicals. This EPA-registered, PAA-based acid sanitizer is tough on beerstone and perfect for everything from kegs to packaging lines. Available in two convenient sizes, it's ideal for coarse sprayers, fermenters, and more. Trusted by pros, designed for performance—Saniclean PAA Pro helps you brew with confidence. Learn more at fivestarchemicals.com. Brew better. Brew with Five Star.FermentisWanna brew a Lager? Discover the whole SafLager™ range by Fermentis. Whether you're looking for floral, fruity, or even estery notes, Fermentis has your back! Want to know more about Fermentis yeasts? Visit www.fermentis.com! BYO Nano+ MembershipGet access to hundreds of hours of on-demand videos covering small craft brewery strategies with BYO's Nano+ Membership. Learn from craft beer experts watching replays of past NanoCon seminars plus a complete library of in-depth workshops. You'll also have full online access to all of BYO's digital content and an annual digital magazine subscription. Check out byo.com/nanoplus for more details.BYO Nano Brew Podcast Episode 67Host: John HollGuests: Lindsay Barr, Ashton LewisContact: nano@byo.comMusic: Scott McCampbell

Molecule to Market: Inside the outsourcing space
The learning curve of a biotech founder/CSO

Molecule to Market: Inside the outsourcing space

Play Episode Listen Later Jul 11, 2025 49:02


In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with Hella Kohlhof, CSO at Immunic. Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with Hella, covering: How the 'waste of two molecules' led to the spin-out creation of Immunic Therapeutics. The perfect blend of a founding team willing to split responsibility, learn and have a go. Ending up as a Nasdaq-listed company via a reverse merger... and all the new challenges that came with it. Immunic's divide-and-conquer global outsourcing strategy, while retaining tight control. Examples of how geopolitical issues have impacted a biotech's growth. Hella leads the Immunic's scientific strategy, including mode of action research, preclinical studies, and biomarker development. Dr. Kohlhof brings deep expertise in immunology, oncology, and drug development, with previous roles at 4SC AG, where she led preclinical and clinical projects. She holds a doctorate in biology from Ludwig Maximilians University of Munich and completed her postdoc at the Helmholtz Centre, focusing on B cell development. She holds several patents, has co-authored numerous publications, and is a regular speaker at scientific and industry events. Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating! Molecule to Market is also sponsored and funded by ramarketing, an international marketing, design, digital and content agency helping companies differentiate, get noticed and grow in life sciences.

Smart Biotech Scientist | Bioprocess CMC Development, Biologics Manufacturing & Scale-up for Busy Scientists
170: Why Your DNA Is a Terrible Disease Predictor (And How Multi-Omics Changes Everything) with Mo Jain - Part 2

Smart Biotech Scientist | Bioprocess CMC Development, Biologics Manufacturing & Scale-up for Busy Scientists

Play Episode Listen Later Jul 10, 2025 22:40


For years, disease diagnosis and treatment have focused on a few biomarkers, overlooking thousands of vital biological signals. Despite biotech advances, most therapies are still based on limited data, missing countless breakthroughs.Multiomics changes that. By analyzing tens of thousands of proteins, metabolites, and lipids, it reveals hidden insights, paving the way for smarter, faster, and more effective medical discoveries.In this must-listen episode, David Brühlmann welcomes Mo Jain, founder and CSO of Sapient, a pioneering force in bringing multiomic platforms out of academia and into the heart of drug development. A physician-scientist by training and a visionary entrepreneur by choice, Mo's journey spans decades at the cutting edge of analytical technologies, culminating in the creation of ultra-high-throughput systems that analyze up to 20,000 biomarkers in a single run for real-world impact.Here are three reasons why this episode needs to be on your playlist:Multiomics at Scale: Mo shares how his team at Sapient turbocharged mass spectrometry, enabling simultaneous measurement of thousands of molecules, transforming routine diagnostics and making previously unimaginable insights accessible to scientists everywhere.Turning Data into Action: Generating vast data is only half the battle. Mo explains how Sapient developed advanced biocomputational teams and frameworks to extract actionable answers, guiding drug developers to faster, smarter decisions and helping avoid the pitfalls that cripple so many omics projects.The Future Is Personalized and Sooner Than You Think: From dramatically earlier disease detection to truly personalized therapies, Mo paints an optimistic picture of a coming era where AI, multiomics, and new therapeutic modalities rapidly accelerate both discovery and delivery, reshaping how biotech companies tackle even the toughest diseases.Ready to break out of the 20-biomarker rut and see what 20,000 data points can reveal? Tune in to discover how you can harness multiomics in your own research and hear Mo's advice for scientists and entrepreneurs venturing beyond the bench.Connect with Mo Jain:LinkedIn: www.linkedin.com/in/mo-jain-md-phd-373895baWebsite: www.sapient.bioCompany LinkedIn Page: https://www.linkedin.com/company/sapientbioNext step:Book a free consultation to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/callDevelop bioprocessing technologies better, faster, at a fraction of the cost with our 1:1 Strategy Call: The quickest and easiest way to excel biotech technology development. Book your call at https://stan.store/SmartBiotechSupport the show

BioSpace
The mRNA Revolution You Haven't Heard About: From Cystic Fibrosis to Personalized Cancer Vaccines

BioSpace

Play Episode Listen Later Jul 10, 2025 14:21


This discussion focuses on how mRNA and self-replicating RNA (srRNA) technologies are expanding far beyond COVID vaccines into revolutionary therapeutic applications for cancer and rare diseases. It is clear that mRNA therapeutics offer three major application areas: infectious disease vaccines, therapeutic vaccines for oncology, and protein replacement for monogenic rare diseases.Today's episode is sponsored by Eclipsebio. From AI-ready datasets to sequencing validation, they drive RNA success. Explore their solutions at https://eclipsebio.com/.Host⁠⁠⁠⁠⁠Lori Ellis⁠⁠⁠⁠⁠, Head of Insights, BioSpaceGuestsAndy Geall, Co-founder and Chief Development Officer, Replicate Bioscience; Chair of the Board, Alliance for mRNA MedicinesPad Chivukula, Co-founder, CSO & COO, Arcturus TherapeuticsDisclaimer: The views expressed in this discussion by guests are their own and do not represent those of their organizations.

Smart Biotech Scientist | Bioprocess CMC Development, Biologics Manufacturing & Scale-up for Busy Scientists
169: Why Your DNA Is a Terrible Disease Predictor (And How Multi-Omics Changes Everything) with Mo Jain - Part 1

Smart Biotech Scientist | Bioprocess CMC Development, Biologics Manufacturing & Scale-up for Busy Scientists

Play Episode Listen Later Jul 8, 2025 25:33


What if the secret to truly personalized precision medicine lies not in your genetic code, but in your zip code?For years, biotech has focused on genomics to explain disease and drug response, but DNA only accounts for a fraction of the story. The real breakthrough? Multi-omics: the large-scale analysis of proteins, metabolites, and lipids, powered by advanced mass spectrometry and AI, offering a fuller picture of human health.In this episode, David Brühlmann meets Mo Jain, founder and CSO of Sapient, a leader in multi-omics analytics. With over two decades of experience across physiology, biomedicine, and computational biology, Mo has been at the forefront of developing scalable multi-omics technologies that are changing the way we predict, diagnose, and treat disease. From leading an academic lab to building a pioneering biotech company, Mo's journey reflects a passion for uncovering the hidden 80–90% of disease risk that lies beyond our genes.Here are three reasons you'll want to listen to this episode:Your Environment Matters More Than Your Genes: Mo explains why your zip code is a stronger predictor of your health than your genetic code, challenging the industry's long-held beliefs and opening new avenues for disease prevention and risk assessment.Multi-omics Disrupts Drug Development: Discover how integrating thousands of biological data points can revolutionize drug discovery by identifying novel targets, better predicting drug response, and accelerating therapeutic breakthroughs that were previously out of reach.Big Data Finally Becomes Actionable: Thanks to rapid advances in mass spectrometry and computational power, scientists can now make sense of overwhelming volumes of multi-omic data, turning what was once information overload into actionable insights for diagnostics and drug development.Ready to think beyond your genes? The biotech revolution is here, and it starts in your neighborhood.Connect with Mo Jain:LinkedIn: www.linkedin.com/in/mo-jain-md-phd-373895baWebsite: www.sapient.bioCompany LinkedIn Page: https://www.linkedin.com/company/sapientbioNext step:Book a free consultation to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/callDevelop bioprocessing technologies better, faster, at a fraction of the cost with our 1:1 Strategy Call: The quickest and easiest way to excel biotech technology development. Book your call at https://stan.store/SmartBiotechSupport the show

Breaking Into Cybersecurity
Breaking into Cybersecurity: Career Journey and Insights with Gavin Reid

Breaking Into Cybersecurity

Play Episode Listen Later Jul 6, 2025 21:39


Breaking into Cybersecurity: Career Journey and Insights with Gavin Reid, CSO at Human SecurityIn this episode of Breaking into Cybersecurity, we are joined by Gavin Reid, Chief Security Officer at Human Security. Gavin shares his extensive career journey from NASA to leading cybersecurity teams at Cisco and Recorded Future, now part of MasterCard. He offers invaluable advice for those seeking to transition from technical roles into leadership positions within cybersecurity. The discussion covers evolving cybersecurity threats, the importance of continuous learning, and how to enable businesses to grow securely. Gavin also discusses the role of threat intelligence, the impact of AI on cybersecurity, and his approach to building effective security teams. Don't miss this insightful conversation on navigating the dynamic world of cybersecurity.00:00 Introduction and Guest Overview00:57 Gavin's Career Journey01:40 Transitioning from Technical to Leadership Roles03:04 Adapting to Industry Changes04:45 Security as a Business Enabler05:17 Navigating Security in Startups06:07 Vendor Perspective and Customer Support07:14 Threat Intelligence Integration11:27 Career Advice for Aspiring Threat Intelligence Analysts15:19 The Role of AI in Cybersecurity18:24 Final Thoughts and Human Security's Mission21:27 Conclusion

The MM+M Podcast
Reimagining pharma-HCP connections: AI, clinical support and the future of field force engagement, a podcast sponsored by Impiricus

The MM+M Podcast

Play Episode Listen Later Jul 2, 2025 26:01


In this special episode of the MM+M Podcast, we sit down with Dr. Osama Hashmi — dermatologist, cofounder and chief product officer at Impiricus — alongside practicing physician Dr. Bilal Ahmed — an interventional/structural cardiologist, cofounder and CSO of Lylah, a personalized microbiome therapeutics company — to explore how artificial intelligence is transforming the way healthcare professionals connect with pharmaceutical resources. We'll dive into how Impiricus and the life science companies it works with are building and leveraging the first and only AI-powered field force enhancement tool designed to streamline real-time communication between HCPs and pharma reps. From clinical decision support to on-demand access to drug information, this conversation unpacks how technology can bridge long-standing gaps in care delivery and engagement.Tune in for a forward-looking discussion on the evolving needs of clinicians, the role of AI in healthcare and how pharma can better support providers in delivering optimal patient outcomes.  Step into the future of health media at the MM+M Media Summit on October 30th, 2025 live in NYC! Join top voices in pharma marketing for a full day of forward-thinking discussions on AI, streaming, retail media, and more. Explore the latest in omnichannel strategy, personalization, media trust, and data privacy—all under one roof. Don't wait—use promo code PODCAST for $100 off your individual ticket. Click here to register! AI Deciphered is back—live in New York City this November 13th.Join leaders from brands, agencies, and platforms for a future-focused conversation on how AI is transforming media, marketing, and the retail experience. Ready to future-proof your strategy? Secure your spot now at aidecipheredsummit.com. Use code POD at check out for $100 your ticket! Check us out at: mmm-online.com Follow us: YouTube: @MMM-onlineTikTok: @MMMnewsInstagram: @MMMnewsonlineTwitter/X: @MMMnewsLinkedIn: MM+M To read more of the most timely, balanced and original reporting in medical marketing, subscribe here.

Irish Tech News Audio Articles
€18.75m Funding Recommended for Two Enterprise Ireland Client Companies in Horizon Europe EIC Accelerator

Irish Tech News Audio Articles

Play Episode Listen Later Jul 2, 2025 5:52


Two Enterprise Ireland-backed companies have won funding approvals of up to €18.75m in the latest competition under Horizon Europe's European Innovation Council (EIC) Accelerator Programme. The two successful companies are CroíValve and Lios. Enterprise Ireland leads the National Support Network for Horizon Europe which helps entrepreneurs to compete and win funding in EIC competitions. To date, 28 Irish companies have secured approvals totalling €175.5m under the EIC Accelerator Programme since the beginning of Horizon Europe in 2021. Trinity College Dublin spin-out company CroíValve is a clinical-stage medical device company focused on developing a minimally invasive device for the treatment of a severe cardiac disease called tricuspid regurgitation. CroíValve's DUO Tricuspid Coaptation Valve system will enable a non-surgical solution for the condition as currently less than one percent of elderly patients receive surgical treatment due to the risks involved in this population. CroíValve previously received funding under the Disruptive Technologies Innovation Fund which is administered by Enterprise Ireland and supports research collaboration to drive disruptive technology development. Lios, a pioneer in acoustic advanced materials technology, is a Dublin company with strong Sligo roots. SoundBounce is an advanced acoustic material developed by Lios that works better than traditional sound dampening materials. Transport, home appliances, power generation, and construction are among the major industries seeking to reduce noise levels. Part of the EU's Horizon Europe 2021-2027 Research and Innovation Programme, the EIC Accelerator Programme provides transformational funding to high-potential, high-risk start-ups, scale-ups and SMEs. Approvals include grant funding of up to €2.5 million combined with an equity investment ranging from €0.5 to €10 million in a blended finance offer. 959 applications were submitted to this latest competition with 150 companies subsequently selected for interview resulting in a total of 40 funding awards to 16 countries. The 40 companies were allocated funding of up to €229m in a combination of grants and equity investments. Almost one third of the selected companies were led by a woman in a key leadership role such as CEO, CTO or CSO. Minister of State for Trade Promotion, AI and Digital Transformation Niamh Smyth TD said: "Today's announcement is testament to the research and innovation capability of Irish companies and the vibrancy of the start-up and commercialisation eco-system. Collaboration between Higher Education, state agencies, investors, and business creates a pathway to success, and the government, through Enterprise Ireland, is committed to helping enterprises like Lios and CroíValve to realise their commercial potential. This announcement provides significant funding to support these companies to bring their innovations to the global market, and I wish both every success for the future." Jenny Melia, CEO Designate, Enterprise Ireland, said: "I'd like to congratulate Lios and CroíValve on their successful applications to the highly competitive EIC Accelerator programme. Both companies, working with the EIC, will be able to enhance their entrepreneurial capability and get the critical support required at this juncture in their development and scaling journey. It is particularly welcome to see that both projects have a female-inclusive leadership team which supports Enterprise Ireland's strategic ambition to increase the participation of women in entrepreneurship and business leadership." Lucy O'Keeffe, Co-Founder & CEO, CroíValve said: "Securing European Innovation Council (EIC) funding is very impactful in supporting full alignment of our novel technology with this complex patient population, along with expansion of clinical validation of our DUO System. There is a real unmet clinical need to provide a scalable treatment option for the heterogeneous patient population with tricuspi...

Fit Mom University - The Podcast

What happens when you're staring down the darkest moment of your life—and instead of breaking, you rise? In this powerful episode, Robert sits down with Kevin Palmieri, the CSO, Founder, and Host of Next Level University, a Top 100 Global Self-Improvement Podcast with over 2,000 episodes and listeners in 175+ countries.Kevin opens up about the day he nearly ended it all—and how that breaking point became his breakthrough. With brutal honesty and heart-driven purpose, he shares how he went all in on his mission to help others grow through holistic, no-BS self-improvement. Whether you're on the edge of change or looking for a sign to go after your dream, this conversation will shake you awake and fuel your next move.

From Lab to Launch by Qualio
Developing the undevelopable with Dave Miller, Chief Science Officer at AustinPx

From Lab to Launch by Qualio

Play Episode Listen Later Jul 1, 2025 44:02


As complexity in pharmaceutical development reaches new heights — especially with over 60% of recent FDA novel molecular entities falling outside traditional drug design rules — the need for advanced formulation and manufacturing strategies has never been greater. Precision medicine is no longer a future goal; it's a present necessity. And that's exactly where AustinPx comes in.At the forefront of this shift is AustinPx's KinetiSol technology, a powerful platform designed to make the “undevelopable” developable — transforming poorly soluble, highly potent small molecules into scalable, patient-ready therapies. Dr. Dave Miller, CSO, has spent more than 20 years in pharmaceutical R&D, helping drug developers navigate the challenges of bioavailability, permeability, and manufacturability for complex molecules.Today, we'll explore with Dave how CDMOs like AustinPx are empowering a new era of personalized treatment—while offering product protection strategies that help biopharma companies stand out in a competitive, cost-sensitive market. Qualio website:https://www.qualio.com/ Previous episodes:https://www.qualio.com/from-lab-to-launch-podcast Apply to be on the show:https://forms.gle/uUH2YtCFxJHrVGeL8 Music by keldez

The Disney Story Origins Podcast
CSO 19c – The Prince of Egypt Part 3

The Disney Story Origins Podcast

Play Episode Listen Later Jun 30, 2025 112:00


Comparing and contrasting “The Prince of Egypt” by Dreamworks Animation with scriptures from The Torah, The Holy Bible, and the Qur'an.  This podcast contains certain copyrighted works that were not specifically authorized to be used by the copyright holder(s), but which we believe in good faith are protected by federal law and the fair use doctrine (Section […] The post CSO 19c – The Prince of Egypt Part 3 first appeared on Cinema Story Origins Podcast.

The Thoughtful Entrepreneur
2223 - How Can Brands Effectively Leverage Influencer Marketing with #Paid's Adam Rivietz

The Thoughtful Entrepreneur

Play Episode Listen Later Jun 27, 2025 17:46


Unlocking Influencer Marketing: A Conversation with Adam Rivietz of #PaidIn a recent episode of The Thoughtful Entrepreneur, host Josh Elledge speaks with Adam Rivietz, CSO and Co-Founder of #Paid, a platform revolutionizing influencer marketing by connecting brands with vetted creators. Adam shares how influencer marketing has evolved, the top challenges brands face, and how to approach creator partnerships more strategically.Navigating the Influencer Marketing LandscapeAdam opens the episode by reflecting on his personal journey, including how he overcame a fear of public speaking through stand-up comedy. This experience, he explains, mirrors the importance of authenticity—a key component in successful influencer marketing. Adam emphasizes that storytelling and genuine experiences resonate deeply, both on stage and in branded content.He goes on to describe the early skepticism brands had toward influencer marketing in 2014, and how platforms like #Paid have helped shift that perception. Today, brands recognize the value of creator-driven campaigns that feel native and personal. Adam discusses how declining organic reach, the rising cost of ads, and content fatigue are major challenges marketers face.#Paid addresses these issues by connecting brands with vetted creators who deliver authentic content and better engagement. The platform also enables creator licensing, allowing brands to run ads through influencers' accounts—boosting trust and conversion rates. Adam notes that enterprise brands and agencies, particularly those with mature digital strategies, benefit most from using #Paid.About Adam Rivietz:Adam Rivietz is the Chief Strategy Officer and Co-Founder of #Paid. He leads the company's strategic direction and is passionate about helping brands scale through authentic creator partnerships.About #Paid:#Paid is a creator marketing platform designed to help enterprise brands and agencies manage influencer campaigns at scale. With a focus on authenticity, #Paid offers tools for creator discovery, campaign execution, and paid media integration.Links Mentioned in this Episode:Adam Rivietz on LinkedIn#Paid Official WebsiteEpisode Highlights:Adam's personal growth journey from public speaking fear to stand-up comedy.The evolution and current state of influencer marketing.How #Paid helps brands overcome content, reach, and advertising challenges.The role of authenticity and creator licensing in successful campaigns.Why enterprise brands and agencies benefit most from #Paid's offerings.ConclusionJosh and Adam highlight a clear truth: authentic, creator-led campaigns are the future of digital marketing. Platforms like #Paid empower brands and agencies to scale these efforts effectively. Whether you're new to influencer marketing or looking to optimize your strategy, building real relationships with creators is the key to driving meaningful results.Apply to be a Guest on The Thoughtful Entrepreneur: https://go.upmyinfluence.com/podcast-guestMore from UpMyInfluence:We are actively booking guests for our The Thoughtful Entrepreneur. Schedule HERE.Are you a 6-figure consultant? I've got high-level intros for...

JSA Podcasts for Telecom and Data Centers
Imaginative's Jen Waltz on Mentorship, Cybersecurity & AI | JSA TV at Channel Partners 2025

JSA Podcasts for Telecom and Data Centers

Play Episode Listen Later Jun 27, 2025 7:46


Defense in Depth
Don't Ask "Can" We Secure It, But "How" Can We Secure It

Defense in Depth

Play Episode Listen Later Jun 26, 2025 28:29


All links and images can be found on CISO Series. Check out this post for the discussion that is the basis of our conversation on this week's episode co-hosted by David Spark, the producer of CISO Series, and Mike Johnson, CISO, Rivian. Joining is Hanan Szwarcbord, vp, CSO and head of infrastructure, Micron Technology. In this episode Embracing growth An urgent need for creativity Get the business context Embrace your inner theater kid Huge thanks to our sponsor, Query.ai Query is a Federated Search and Analytics platform that builds a security data mesh, giving security teams real-time context from all connected sources. Analysts move faster and make better decisions with AI agents and copilots that handle the grunt work and guide each step. Learn more at query.ai

Smart Biotech Scientist | Bioprocess CMC Development, Biologics Manufacturing & Scale-up for Busy Scientists
164: How Moss Enables Production of Unproducible Protein Therapeutics with Andreas Schaaf - Part 2

Smart Biotech Scientist | Bioprocess CMC Development, Biologics Manufacturing & Scale-up for Busy Scientists

Play Episode Listen Later Jun 19, 2025 19:17


From lab curiosity to commercial reality. Here's what happens when moss meets the brutal economics of bioprocessing.In Part 1, you've heard the science behind moss-based protein production. Now comes the real test: Can it survive the gauntlet of regulatory scrutiny, cost pressures, and manufacturing scale-up that crushes most biotech innovations?In Part 2 of this groundbreaking conversation, David Brühlmann and Andreas Schaaf, Managing Director and CSO of Eleva, dive into the nuts and bolts of what it actually takes to commercialize a revolutionary production platform. Andreas doesn't just theorize—he's lived through 15+ years of transforming Eleva from startup concept to clinical-stage reality, navigating every regulatory hurdle and economic challenge along the way.Three game-changing advantages that caught our attention:Process Robustness That Actually Works: While CHO cells throw tantrums over minor parameter shifts, moss maintains consistent product quality even when your bioprocess isn't behaving perfectly; a lifeline for manufacturing teams dealing with real-world variability.Economics That Make CFOs Smile: Forget expensive viral filtration steps and costly human pathogen testing. Moss's plant heritage eliminates these animal-system burdens, directly impacting your bottom line in ways that matter.Operational Simplicity: Variability in process ingredients and streamlined cell banking contribute to long-term cost and operational efficiencies that compound over time.Andreas shares hard-won insights about what it really takes to challenge entrenched bioprocessing orthodoxy, including the regulatory conversations, the economic realities, and his advice for scientists brave enough to pursue game-changing innovations.Ready to understand how disruptive biotechnology actually makes it from bench to bedside?Connect with Andreas Schaaf:LinkedIn: www.linkedin.com/in/andreas-schaaf-b3797716Website: www.elevabiologics.comNext step:Book a free consultation to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/callDevelop bioprocessing technologies better, faster, at a fraction of the cost with our 1:1 Strategy Call: The quickest and easiest way to excel biotech technology development. Book your call at www.bruehlmann-consulting.com/call/Support the show

Medical Spa Insider
Choosing Positivity with the Help of Your Brain Trust: Kendra Bracken-Ferguson

Medical Spa Insider

Play Episode Listen Later Jun 18, 2025 42:50


This week, AmSpa President and CSO, Cathy Christensen, speaks with Kendra Bracken-Ferguson, celebrated entrepreneur, founder of BrainTrust and author of The Beauty of Success: Start, Grow and Accelerate Your Brand. They discuss her entrepreneurial journey from building brands to owning in the beauty space, how she evaluates opportunities, and the ways she protects her mental wellness with the help of her community. Listen for: Aligning opportunities with her four pillars: community, mentorship, education, capital; How she knows when it's time to pivot, take a leap or let go of an opportunity; Her nonprofit's efforts for diversity and mentorship in the beauty industry; The importance of building a strong community of trusted partners; Finding joy and managing stress to protect your wellness; Kendra's advice for maintaining positivity in challenging times; Her upcoming ventures in wellness, retail, podcasting and more! Kendra shares more about the power of building your brain trust in her presentation “Community and Counsel: Building Your Brain Trust” on October 4, 2025, at the Women in Aesthetics Leadership Conference. Register to learn why no founder should navigate the path alone and how you can build the counsel you need for sustainable leadership and self-motivation. -- Music by Ghost Score

Smart Biotech Scientist | Bioprocess CMC Development, Biologics Manufacturing & Scale-up for Busy Scientists
163: How Moss Enables Production of Unproducible Protein Therapeutics with Andreas Schaaf - Part 1

Smart Biotech Scientist | Bioprocess CMC Development, Biologics Manufacturing & Scale-up for Busy Scientists

Play Episode Listen Later Jun 17, 2025 23:48


What if the future of "impossible" protein therapeutics is hiding in your backyard?For decades, CHO cells have ruled the biotech kingdom as the undisputed champions of complex protein production. But here's the uncomfortable truth: countless breakthrough therapies are gathering dust on laboratory shelves—not because the science failed, but because traditional hosts can't produce them.Enter moss. Yes, moss. That humble green organism clinging to rocks and trees might just be the biotech industry's best-kept secret.In this eye-opening episode, David Brühlmann sits down with Andreas Schaaf, Managing Director and CSO of Eleva, who's spent over 20 years turning the "impossible" into reality. Andreas didn't just stumble upon moss; he co-developed Eleva's revolutionary moss-based platform from wild concept to commercial-scale game-changer, propelling the company into clinical trials.Here are three reasons why this episode is worth listening to:Moss as a Game Changer: More than a plant, moss is a higher eukaryote with mammalian-like protein production, including post-translational modifications and human-compatible glycosylation.Overcoming Bioprocessing Barriers: CHO cells are the industry gold standard, especially for monoclonal antibodies. But what about the therapeutic proteins that CHO can't handle? Many promising candidates end up shelved—not because the science isn't sound, but because existing production platforms hit their limits.Bioprocessing, Simplified: Moss grows in standard bioreactors using familiar workflows—just with a whole organism instead of suspended cells.Curious about how plant-based systems could solve your protein production challenges? Dive into this episode to discover how moss could revolutionize your approach to challenging proteins; and let us know about your own production hurdles.Connect with Andreas Schaaf:LinkedIn: www.linkedin.com/in/andreas-schaaf-b3797716Website: www.elevabiologics.comNext step:Book a free consultation to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/callDevelop bioprocessing technologies better, faster, at a fraction of the cost with our 1:1 Strategy Call: The quickest and easiest way to excel biotech technology development. Book your call at www.bruehlmann-consulting.com/call/Support the show

CSO Audio Program Notes
CSO Program Notes: Muti Conducts Verdi Requiem

CSO Audio Program Notes

Play Episode Listen Later Jun 12, 2025 16:12


Verdi's Requiem Mass, in its fervent quest for eternal rest, stands as a powerful demonstration of the composer's ability to harness the human voice. Hailed by NPR as “simply magnificent” for their two-time Grammy Award-winning CSO Resound recording of this work, Riccardo Muti and the Chicago Symphony Orchestra and Chorus are joined by a thrilling quartet of international singers to once again deliver a masterful blend of passion and precision. Please note: This program replaces Berlioz's The Damnation of Faust. Learn more: cso.org/performances/24-25/cso-classical/muti-verdi-requiem

The Kubik Report
Patrick Nielander: What a Lifetime of Law Enforcement Should Teach Us - LA Riots

The Kubik Report

Play Episode Listen Later Jun 11, 2025 37:27


Patrick Nielander has spent nearly 40 years in the field of Law Enforcement.  Seven years of Federal Court experience (CSO, Special Deputy US Marshal) and five years as the District Supervisor (CSO Program, JSD7/SIN, District 28).   Served as the Assistant Section Commander for the Medical Department of the Marion County Jail, Indianapolis, Indiana. Responsible for over 3,000 inmates.   Have acquired police patrol experience, correctional healthcare experience, and business management experience.   Previously a Law Enforcement Officer (Sgt., Retired) at the Indianapolis Metropolitan Police Department • Marion County Sheriff's Department (Merged Police Departments) and Indianapolis International Airport (Sgt.)   Have held the position of Assistant Branch Manager for Airport Security serving a national security company at the Indianapolis International Airport. Served as adjunct faculty in the criminal justice program of a national university.  His father and Uncle Gary have been elders in the United Church of God, with whom I have become well-acquainted in my ministry.   We discuss thought-provoking issues about living in and being responsible in an unjust world.  

Ignite Digital Marketing Podcast | Marketing Growth Tips | Alex Membrillo
#162 - How to Layer 3P Data and Reach Ideal Patients

Ignite Digital Marketing Podcast | Marketing Growth Tips | Alex Membrillo

Play Episode Listen Later Jun 10, 2025 16:36


First-party data can only take you so far. To scale your healthcare marketing strategy and reach high-intent patients, you need to tap into third-party audiences. Cardinal's CGO, Lauren Leone, and CSO, Rich Briddock, break down how to use third-party data to improve targeting, reach clinical and payer-based segments, and overcome data limitations.The discussion also covers the costs and platforms for activating these audiences, providing you with a comprehensive understanding of how to integrate them into your marketing strategy to improve lead quality and operational efficiency. RELATED RESOURCES Reaching the Right Patients with 3P Data - https://www.cardinaldigitalmarketing.com/healthcare-resources/podcast/reaching-right-patients-with-3p-data/ How Meta's Data Restrictions Impact Healthcare Advertising Strategies - https://www.cardinaldigitalmarketing.com/healthcare-resources/blog/meta-announces-major-changes-healthcare-advertising/ 10 Ways to Succeed on Meta in 2025 - https://www.cardinaldigitalmarketing.com/healthcare-resources/blog/10-ways-to-succeed-on-meta-in-2025/ 5-Step Paid Media Strategy to Attract Your Ideal Patients - https://www.cardinaldigitalmarketing.com/healthcare-resources/blog/paid-media-patient-acquisition-guide/#)-implement-advanced

The Brave Marketer
Decentralizing Your Digital Identity With Unstoppable Domains

The Brave Marketer

Play Episode Listen Later Jun 4, 2025 32:03


Sandy Carter, COO and Head of GTM at Unstoppable Domains, discusses the potential of on-chain and digitized identities, including real-world examples that highlight shortcomings of current systems. She also reveals details of the new .BRAVE domain and its significance for the Brave community. Key Takeaways:  How Unstoppable domains allows users to store verified digital identity information securely The convergence of AI and blockchain technology, including the potential of AI agents within crypto wallets The launch of the new.BRAVE domain and why this is such an exciting announcement for the Brave community Guest Bio: Sandy Carter is a globally recognized expert and innovator in AI and blockchain, having led groundbreaking advancements in AI and blockchain. Currently, as COO of Unstoppable Domains—a leading digital identity platform—she is revolutionizing how users manage and own their online identities. Formerly COO, CPO, and CSO at AWS and IBM, Sandy has successfully driven billions in revenue growth and spearheaded transformative technology adoption at scale. Sandy is author of the bestselling book “AI First, Human Always”, and has been recognized as a Microsoft MSN Top 10 AI Entrepreneur. She has been featured in Adweek's AI Power 100, and honored by Constellation Research as a Top AI Business Leader. She has delivered keynote addresses at global forums such as CES, SXSW, Davos, and more, and has been consistently rated among the top speakers. An accomplished global speaker, she has captivated audiences of up to 50,000 attendees in over 89 countries (and has proudly sampled McDonald's in each one). ---------------------------------------------------------------------------------------- About this Show: The Brave Technologist is here to shed light on the opportunities and challenges of emerging tech. To make it digestible, less scary, and more approachable for all! Join us as we embark on a mission to demystify artificial intelligence, challenge the status quo, and empower everyday people to embrace the digital revolution. Whether you're a tech enthusiast, a curious mind, or an industry professional, this podcast invites you to join the conversation and explore the future of AI together. The Brave Technologist Podcast is hosted by Luke Mulks, VP Business Operations at Brave Software—makers of the privacy-respecting Brave browser and Search engine, and now powering AI everywhere with the Brave Search API. Music by: Ari Dvorin Produced by: Sam Laliberte  

The Disney Story Origins Podcast
CSO 19b – The Prince of Egypt Part 2

The Disney Story Origins Podcast

Play Episode Listen Later May 30, 2025 81:00


Comparing and contrasting “The Prince of Egypt” by Dreamworks Animation with scriptures from The Torah, The Holy Bible, and the Qur'an.  This podcast contains certain copyrighted works that were not specifically authorized to be used by the copyright holder(s), but which we believe in good faith are protected by federal law and the fair use doctrine (Section […] The post CSO 19b – The Prince of Egypt Part 2 first appeared on Cinema Story Origins Podcast.

ITSPmagazine | Technology. Cybersecurity. Society
Holding the Line on Quality in an AI-Driven SDLC | An OWASP AppSec Global 2025 Conversation with Sarah-Jane Madden | On Location Coverage with Sean Martin and Marco Ciappelli

ITSPmagazine | Technology. Cybersecurity. Society

Play Episode Listen Later May 30, 2025 14:48


In this On Location episode during OWASP AppSec Global 2025 in Barcelona, Sarah-Jane Madden brings a unique lens to application security, shaped by her journey from developer to security leader and CSO. Speaking at OWASP AppSec Global, she tackles one of today's most pressing concerns: how AI is reshaping software engineering—and how we must respond without compromising core values like quality and security.Madden emphasizes that AI is only the latest in a series of major disruptions, comparing it to shifts like remote work triggered by COVID. Her message is clear: organizations must prepare for continuous change, not just chase the current trend. That means prioritizing adaptability and ensuring critical practices like application security are not sacrificed in the rush to speed up delivery.She makes the case for a layered, iterative approach to development—rejecting the outdated linear mindset. Developers, she argues, should leverage AI as an accelerator, not a replacement. Think of AI as your digital intern: handling the drudgery, automating boilerplate code, and even applying internal security standards to code before it reaches human hands. This frees developers to focus on creative problem-solving and thoughtful architecture.However, Madden cautions against blind enthusiasm. While experimentation is healthy, organizations must be discerning about outcomes. Speed is meaningless without quality, and quality includes security. She calls on developers to advocate for high standards and reminds business leaders not to fall for the allure of shortcut statistics or flashy claims that promise results without skilled labor. Her analogy of microwave dinners vs. proper cuisine illustrates the risk of prioritizing convenience over substance—especially in complex problem-solving environments.For line-of-business leaders, Madden urges realistic expectations. AI can enhance productivity, but it doesn't eliminate the need for thoughtful development. Ultimately, customers will notice if quality drops, and reputational damage is hard to undo.In closing, Madden celebrates OWASP as more than an organization—it's a source of support, camaraderie, and genuine community for those working to build secure, reliable systems. Her message? Embrace change, use tools wisely, protect your standards, and never forget the human side of engineering.GUEST: Sarah-Jane Madden | Global Director of Cyber Defense at Fortive | https://www.linkedin.com/in/sarahjanemadden/HOST: Sean Martin, Co-Founder at ITSPmagazine and Host of Redefining CyberSecurity Podcast | https://www.seanmartin.comSPONSORSManicode Security: https://itspm.ag/manicode-security-7q8iRESOURCESLearn more and catch more stories from OWASP AppSec Global 2025 Barcelona coverage: https://www.itspmagazine.com/owasp-global-appsec-barcelona-2025-application-security-event-coverage-in-catalunya-spainCatch all of our event coverage: https://www.itspmagazine.com/technology-and-cybersecurity-conference-coverageWant to tell your Brand Story Briefing as part of our event coverage? Learn More

The Disney Story Origins Podcast
CSO 19a – The Prince of Egypt Part 1

The Disney Story Origins Podcast

Play Episode Listen Later May 29, 2025 83:00


Comparing and contrasting “The Prince of Egypt” by Dreamworks Animation with scriptures from The Torah, The Holy Bible, and the Qur'an.  This podcast contains certain copyrighted works that were not specifically authorized to be used by the copyright holder(s), but which we believe in good faith are protected by federal law and the fair use doctrine (Section […] The post CSO 19a – The Prince of Egypt Part 1 first appeared on Cinema Story Origins Podcast.