Whatever business you are in, it is important that you have a clear view of your process and who you are dealing with. Dive in as Kevin Brenner shares his insights on how to automate your podcasting to streamline your process, connect with guests, and key takeaways to develop show notes. WHAT TO LISTEN FOR Simplifying your podcasting process Is it a smart idea to do a pre-interview call? Ways to create an impressive show notes Should you seek post-production and marketing support? Powerful tips to get started with podcasting RESOURCES/LINKS MENTIONED Zapier Calendly Zoom ClickUp Canva Alitu Headliner ABOUT KEVIN BRENNER Kevin Brenner is a University of Miami graduate with a Bachelors in Atmospheric Science and top Pentagon Air Force meteorologist, Kevin is not your typical Wall Street fund manager. Rather than pursue an expensive finance degree, Kevin spent years meticulously educating himself in every facet of multifamily real estate from syndications to underwriting to fund management. Apart from serving his country, Kevin is a well-recognized investor, coach, mentor, and host of the top-rated Active Duty Passive Income Podcast. With over 250,000+ downloads worldwide, Kevin's growing influence and network in the real estate space has helped him expand his personal multifamily portfolio. A passionate educator, Kevin is Active Duty Passive Income's Director of Single-Family Education where he coaches over 150+ military real estate investors on how to succeed in real estate. CONNECT WITH KEVIN Website: Nimbus Capital Podcast: The Active Duty Passive Income Podcast IG: @investorkev LinkedIn: Kevin Brenner Special shout out to Cityside Capital! You just got 1 entry into getting our services at no cost for leaving an honest rating and review this month of January! Kindly get in touch with us at email@example.com to get more chances of winning. “True value! The value that Adam provides is UNMATCHED!! I appreciate the willingness to share the tips and tricks that make a podcast go. Thank you!” To learn more on how to win our awesome packages, listen to our 100th episode: Ep100: What Your Podcast Can Do For Your Business (Special Episode) CONNECT WITH US Thinking about creating and growing your own podcast but not sure where to start? Visit GrowYourShow.com and Schedule a call with Adam A. Adams! If you are looking to upgrade your podcast equipment or get your inexpensive mic that works great, go to Growyourshow.com/pdf
Der zweite Teil unseres Interviews mit Hansjörg Weis vom Plonhof in Tramin startet mit der Verkostung eines wahren Klassikers - dem Williams. Ohne Übertreibung: Einen besseren haben wir bisher nicht getrunken! Burkhards eindeutiger Kommentar: „Es gibt auch andere, die versuchen, Schnaps zu brennen, aber nicht jeder kann´s“. Hansjörg Weis ist ein Kunsthandwerker am Brennkessel, der die Seele der Frucht in seinen Bränden meisterlich konserviert. Höre, was der eigentliche Obstbauer und passionierte Brenner über Reifezeitpunkt und Gärung verrät und warum die Quitte keinen Fehler verzeiht. Du erfährst, welches Zukunftsprojekt er mit dem „Leben des Weins“ auf der Schiene hat, das wir schon probieren durften, und wo du seine Destillate probieren und kaufen kannst. Floral, Fruchtig, natürlich: So sind die Aromen-Destillate vom Plonhof - einfach was Gutes! Abonniere jetzt den Podcast bei Google und verpasse keine Folge mehr! Die Aromen-Destillate aus Tramin findest du hier: https://www.plonhof.com https://www.wein-suedtirol.it https://www.hofstatter.com ********************************************** Abonniere jetzt den Podcast bei Google und verpasse keine Folge mehr! Mehr findest du auch auf den Social-Media-Kanälen https://www.facebook.com/feinschmeckertouren/ https://www.youtube.com/channel/UCa_CkAeidqAQ98nKFa0HZcg/featured?view_as=public https://www.instagram.com/feinschmeckertouren/ Feinschmeckertouren In unserem Genuss-Cast lernst du Food- und Feinkostadressen, Weine und Winzer, Restaurants und Spezialitäten-Manufakturen kennen. Als Individualisten entdecken wir auf unseren Reisen gerne Neues aus der Welt der Kulinarik. Begleite uns dabei und profitiere von unseren persönlichen Impressionen und Insidertipps jenseits vom Mainstream-Tourismus! Neben Weinverkostungen und Tipps für die Kombination mit passenden Speisen hörst du hier kurzweilige Geschichten über Wein, Olivenöl, Grappa, Obstbrände, Käse, Gewürze und Co. Du bekommst Impulse über gastronomische Highlights mit außergewöhnlicher Küche und urtypischem Flair, egal ob Sterneküche oder Trattoria. Außerdem erfährst du Unterhaltsames über Städte und Regionen. In den Interviews mit „Genusshandwerkern“ geht es um die Menschen hinter den Produkten und ihre individuelle Story. Du bekommst Einblicke in die Geheimnisse ihrer Produktphilosophie sowie die Herstellung und Veredelung, Umgebung oder Zubereitung ihrer Lebens- und Genussmittel. Mit Geschichten von unseren Entdeckertouren, auch aus den mediterranen Ländern Italien, Frankreich und Spanien, wollen wir dich inspirieren, das Leben mit kulinarischen Highlights zu genießen! Wenn auch du Produkte mit eigener Handschrift, die Vielfalt der Aromen von natürlichen Lebensmitteln und deren intensiven Genuss liebst, dann bist du in dieser Show genau richtig. Viel Spass beim Hören und Genießen!
Elise Brenner PhD, is an Associate Professor in the Department of Public Health at Simmons University in Boston and is an instructor in the Department of Anthropology at Bridgewater State University in Bridgewater, Massachusetts. Brenner is a Reiki Master Practitioner & Teacher, Mindfulness Meditation Teacher is committed to wellness equity in all of the services she provides. The owner of Brenner Reiki Healing in Newton, Massachusetts, Elise provides comprehensive training in all levels of Reiki, having trained physicians, nurses, social workers, physical therapists, teachers, and people of all ages and backgrounds. Brenner has provided Reiki training for staff at Boston's Beth Israel Deaconess Medical Center staff, Edith Nourse Rogers Veterans Administration Hospital in Bedford, MA, and Tufts Medical Center in Boston. Nancy Spatz, MD, Reiki Master Teacher, graduated from Boston University School of Medicine in 1990. Nancy's training continued at Beth Israel Hospital-Harvard Medical School, where she completed her Psychiatry training in 1994. After witnessing the ongoing hardships that people experience with medical and emotional illness, Nancy found that the combination of her medical knowledge and Reiki practice helped people calm the mind, settle the body, and heal. Nancy's care for others became the impetus to get the word out so all of us can experience the benefits of Reiki self-practice. Sign up for 10% off of Shrink Rap Radio CE credits at the Zur Institute
Für die 77. Folge, also eine echte Schnapszahl, haben wir uns einen wahren Spirituosenkenner eingeladen, Helmut Knöpfle. Der bekennende Whisky-Fan startete vor über 30 Jahren bei Coca Cola in die Welt der Getränke, fand aber dann in Tennessee seine wahre Bestimmung. Weitere Stationen führten ihn rund um die Welt und in über 4.000 Whiskyverkostungen und -seminare, die er leitete. Seit Januar 2022 ist Helmut nun in Oberbayern heimisch geworden, wo er für die Destillerie Lantenhammer neue Strategien entwickelt. Im Podcast erzählt er über seine bewegte und teils auch beschwipste Geschichte und berichtet, was einen Whisky-Fachmann wie ihn auch heute noch antreibt, ständig auf der Suche nach neuen Entdeckungen und Informationen zu sein...
For naturalist, writer and photographer, Kelly Brenner noticing details is a way of life. With the deep curiosity of a naturalist, Kelly has discovered some of the incredible natural diversity around her and documented this in her bookNature Obscura: A city's hidden natural world. Listen to hear more about:The story behind the title of Kelly's book Nature Obscura.The diversity of habitats that can be found in Seattle and the wildlife that makes its home there.The types of invertebrates found in cities.Kelly's natural history tools (microscopes, hand lens and a simple flashlight).The magic world of tardigrades and slime moulds.The way that nature adapts, both behaviourally and biologically, to the urban environment. Ideas for increasing biodiversity in cities. How you can start to become a backyard naturalist yourself, wherever you live.To find out more about Kelly and her work, visit her website: http://www.metrofieldguide.com. You can also find Kelly on Twitter and Instagram. If you would like to support Kelly's work, you can do so via Patreon: https://www.patreon.com/kellybrenner-----------------Sign-up for Journaling With Nature's Newsletter to receive news and updates as well as the Nature Journaling Inspiration List each month! You can support Journaling With Nature Podcast on Patreon, Your contribution is deeply appreciated. Thanks for listening!
Direkt aus den Junioren ist Marco Brenner Anfang 2021 in die WorldTour gewechselt. Im Podcast spricht der DSM-Profi über wichtige Lektionen, große Sprünge, hoch gesteckte Ziele und sein eigenes Junioren-Team.
The first guest on today's episode of the AWF Union Podcast was IATSE Local 160 Business Agent John Galinac. He spoke about how the stage industry has been affected by the COVID-19 pandemic. He also discussed how Local 160 has taken to the COVID-19 vaccine. Roofers and Waterproofers Local 96 Business Agent Nick Brenner was also featured on today's episode. He discussed how unions in the area, particularly in Wisconsin, have been affected by So-Called “Right to Work” laws. He also said their membership is greatly benefiting from their new training center.
Retired local business owner, political strategist, and townhall.com contributor Barney Brenner joins Chris for a news roundup. Chris and Barney discuss Pima County Attorney Laura Conover's decision to stop charging cases of simple drug possession from December 15 until February 15th because...COVID. It's part of Pima County's plan to reduce jail population while they fire half of the guards at the jail. Chris also gives kudos to AZPM for issuing a balanced news report citing that many people in area hospitals are not there due to COVID. Barney also talks calendars with Chris... Search for Barney's columns at townhall.com
Die neue Corona-Variante Omikron macht Ärzten Angst: Der Leiter der Intensivstationen der Uniklinik Essen, Professor Thorsten Brenner, blickt „mit sehr großer Vorsicht“ auf die Entwicklung in Großbritannien, wo sich die Mutation „dramatisch ausbreitet“. Sein Team stehe einer solchen auch in Deutschland möglichen Entwicklung mit „gespannter Erwartungshaltung gegenüber“, so Brenner bei „19 – die Chefvisite“. Zwar drohe aktuell keine Überlastung. Im Ernstfall fürchte er aber, dass sich nicht von Covid betroffene Patienten „hintenanstellen müssen“. Corona „können wir nur mit Impfen und Boostern bekämpfen“, betont Brenner. Nebenwirkungen seien „extremst selten“, es gebe daher „keine Ausrede mehr, sich vor der Impfung zu drücken“. Für Familienfeiern zu Weihnachten empfiehlt der Mediziner, die 2G-Regel „hart umzusetzen“ und sich nur mit Geimpften und Genesenen zu treffen – und zur Sicherheit „am besten noch zusätzlich“ einen Test zu machen. Im Videocast „19 – die Chefvisite“ gibt der Chef der Uniklinik Essen, Professor Jochen A. Werner, zusammen mit Publizist Jens de Buhr und wechselnden Gästen von Montag bis Freitag Orientierung bei den aktuellen Entwicklungen der Corona-Pandemie. Alle Sendungen sind jederzeit abrufbar in der Mediathek auf DUP-magazin.de!
Hello beautiful Humans!! I hope you really enjoy this episode with returning guest, Mariko!!! In this episode, Mariko shares about her latest additions to her coaching business such as EFT Tapping and Hypnosis. She shares her experience in becoming an author and now shifting into a Love Coach. Be sure to check out Mariko's social media & offerings! https://www.instagram.com/marikobrenner/ https://www.marikobrenner.com/ Thanks for listening!
Dr. Andrew Brenner is an Assistant Professor in the Department of Religion and Philosophy at Hong Kong Baptist University. In this interview, we talk about his new paper on God, grounding, and abstract objects. The Paper: https://philpapers.org/rec/BREHDG -------------------------------- GIVING -------------------------------- Please consider becoming a Patron! I am a full-time student, so your support helps make our content better and provides me Ramen money. Patreon (Thanks!): https://www.patreon.com/AdherentApologetics YouTube Membership: https://www.youtube.com/channel/UCO8jj_CQwrRRwwwXBndo6nQ/join
Do you know how many lives Zev Brenner has saved through his radio career? Zev Brenner has gone above and beyond to create a radio station for the Jewish People called Talkline Network. There are channels for all walks of life, but not for the Jews. That is where Zev Brenner steps in. He saw there was a need and he filled it. Tune in to find out how Zev Brenner has turned a Neturei Karta leader from anti zionist into a zionist, I don't know that many people who can do that. Thank you to our sponsors of this weeks episode. Skyscraper Insurance: https://skyscraperinsurance.com/ (https://skyscraperinsurance.com) Siyatta: https://www.siyatta.com/ (https://www.siyatta.com) DetailsByDaniella: https://www.instagram.com/detailsbydaniella/ (https://www.instagram.com/detailsbydaniella/) The Homeowners Show: https://api.whatsapp.com/send?phone=18452372779&text=Hi,%20i%20would%20like%20to%20know%20more%20info (https://api.whatsapp.com/send?phone=18452372779&text=Hi,%20i%20would%20like%20to%20know%20more%20info) Follow Hebrew Hits on all streaming apps and on Youtube. https://www.instagram.com/hebrew_hits/ (https://www.instagram.com/hebrew_hits/) https://www.youtube.com/channel/UCORiiT9WKpUk9cmmBpWJk-A (https://www.youtube.com/channel/UCORiiT9WKpUk9cmmBpWJk-A)
Townhall.com contributor, retired business owner, and local political pundit, Barney Brenner joins Chris today for hours 1 and 2. Search for Barney's columns at townhall.com Barney and Chris discuss the county's threat of lawsuit over differential water rates and other issues in the news
ownhall.com contributor, retired business owner, and local political pundit, Barney Brenner joins Chris today for hours 1 and 2. Search for Barney's columns at townhall.com Barney and Chris preview the 2022 US Senate race as we know it today. They then tap into Barney's experience on campaigns to discuss strategies for winning. Hour 3 Ted Maxwell, President and CEO of SALC on drawing legislative districts
Welcome to PsychEd, the psychiatry podcast for medical learners, by medical learners. This episode covers suicide epidemiology, and prevention with Dr. Juveria Zaheer, a Clinician Scientist with the Institute for Mental Health Policy Research, and Education Administrator in the Gerald Sheff and Shanitha Kachan Emergency Department at CAMH in Toronto, Ontario. She is also an Assistant Professor in the Department of Psychiatry at the University of Toronto. She utilizes both quantitative and qualitative methods to better understand suicide and identify areas of potential improvement. The learning objectives for this episode are as follows: By the end of this episode, you should be able to… Develop an awareness of suicide risk and prevalence, as it pertains to the general population and psychiatric populations Incorporate additional contextual information into suicide risk assessment that goes beyond SADPERSONS and other list-based approaches Develop a deeper understanding of how to approach and help individuals with suicidal thoughts and behaviours Guest expert: Dr. Juveria Zaheer Hosts: Dr. Chase Thompson (PGY4) Episode production: Dr. Weam Sieffien, Dr. Vincent Tang, and Dr. Chase Thompson Audio editing: Dr. Chase Thompson Show notes: Dr. Chase Thompson 00:00 – Introduction 01:14 – Learning objectives 04:00 – Overview of suicide rates across populations 07:20 - Sex and gender differences in suicide 08:50 - Suicide following discharge from hospital 14:10 - Finding suitable dispositions for individuals dealing with suicidal thoughts and behaviors 20:50 - Meeting patients and families where they are at 23:30 - Suicide safety plans 28:30 - Evidence-based approaches to suicide prevention 32:30 - Commentary on strength of evidence for interventions in suicide prevention 38:40 - Addressing suicidality in borderline personality disorder 47:00 - Ethics of involuntary hospitalization for suicidality 50:00 - Future of suicide prevention References: Borecky, A., Thomsen, C., & Dubov, A. (2019). Reweighing the ethical tradeoffs in the involuntary hospitalization of suicidal patients. The American Journal of Bioethics, 19(10), 71-83. Cipriani, A., Hawton, K., Stockton, S., & Geddes, J. R. (2013). Lithium in the prevention of suicide in mood disorders: updated systematic review and meta-analysis. Bmj, 346. Chung, D., Hadzi-Pavlovic, D., Wang, M., Swaraj, S., Olfson, M., & Large, M. (2019). Meta-analysis of suicide rates in the first week and the first month after psychiatric hospitalisation. BMJ open, 9(3), e023883. Chung, D. T., Ryan, C. J., Hadzi-Pavlovic, D., Singh, S. P., Stanton, C., & Large, M. M. (2017). Suicide rates after discharge from psychiatric facilities: a systematic review and meta-analysis. JAMA psychiatry, 74(7), 694-702. Guzmán, E. M., Cha, C. B., Ribeiro, J. D., & Franklin, J. C. (2019). Suicide risk around the world: a meta-analysis of longitudinal studies. Social psychiatry and psychiatric epidemiology, 54(12), 1459-1470. Kessler, R. C., Bossarte, R. M., Luedtke, A., Zaslavsky, A. M., & Zubizarreta, J. R. (2020). Suicide prediction models: a critical review of recent research with recommendations for the way forward. Molecular psychiatry, 25(1), 168-179. Mann, J. J., Apter, A., Bertolote, J., Beautrais, A., Currier, D., Haas, A., ... & Hendin, H. (2005). Suicide prevention strategies: a systematic review. Jama, 294(16), 2064-2074. Miller, I. W., Camargo, C. A., Arias, S. A., Sullivan, A. F., Allen, M. H., Goldstein, A. B., ... & Ed-Safe Investigators. (2017). Suicide prevention in an emergency department population: the ED-SAFE study. JAMA psychiatry, 74(6), 563-570. Sakinofsky, I. (2014). Preventing suicide among inpatients. The Canadian journal of psychiatry, 59(3), 131-140. Stanley, B., Brown, G. K., Brenner, L. A., Galfalvy, H. C., Currier, G. W., Knox, K. L., ... & Green, K. L. (2018). Comparison of the safety planning intervention with follow-up vs usual care of suicidal patients treated in the emergency department. JAMA psychiatry, 75(9), 894-900. Zaheer, J., Jacob, B., de Oliveira, C., Rudoler, D., Juda, A., & Kurdyak, P. (2018). Service utilization and suicide among people with schizophrenia spectrum disorders. Schizophrenia research, 202, 347-353. Zaheer, J., Links, P. S., & Liu, E. (2008). Assessment and emergency management of suicidality in personality disorders. Psychiatric Clinics of North America, 31(3), 527-543. CPA Note: The views expressed in this podcast do not necessarily reflect those of the Canadian Psychiatric Association (CPA). For more PsychEd, follow us on Twitter (@psychedpodcast), Facebook (PsychEd Podcast), and Instagram (@psyched.podcast). You can provide feedback by email at firstname.lastname@example.org. For more information, visit our website at psychedpodcast.org.
FTI Kollege Luca Picone ist da und er kennt sich bestens in Italien aus. Luca klärt auf über eine unaufdringliche Region, die extrem viel zu bieten hat. Traumhafte grüne Landschaften, die Alpen, Lago Maggiore, weißer Trüffel, leckerste Osteria-Küche, beste Weinsorten und dann auch noch die Hauptstadt der Schokolade. Insgesamt ganz hohe Qualität. Eine Genussreise durch das Piemont, die zum Beispiel in Turin beginnen kann. Inhalt 00:00:38 Das Piemont und die Kirsche 00:02:40 Weißer Trüffel von Alba 00:05:41 Lago Maggiore 00:07:08 Slow Food Kultur 00:10:08 Asti & Barolo 00:12:45 Osteria 00:13:43 Eigenanreise 00:14:50 Turin 00:18:48 Beste Reisezeit 00:21:07 Über den Brenner 00:22:23 Ferrero Gründung Dir stehen folgende Informationsquellen und Kontaktmöglichkeiten zur Verfügung: https://www.fti.de/service/reisehinweise.html https://www.fti.de/blog/reiseberichte-und-tipps/expertentipps/urlaub-corona-einreisebestimmungen/ Schreib uns deine Fragen, Reiseerlebnisse und Reisetipps an email@example.com
Episode description: Betsy is a long-time tennis coach, retired hospital attorney, and the author of a memoir titled The Longest Match: Rallying to Defeat an Eating Disorder in Midlife. Her inspiring message is that it is never too late to be a work in progress. Betsy is also an eating disorder recovery speaker, advocate, and peer support mentor who shows that it is possible to heal from past trauma and become healthier in body, mind, and spirit. In this episode of Peace Meal, Betsy discusses how she was taught to suppress her emotions growing up, how dealing with her trauma was the only way to recover from her eating disorder, and how you're never too old to start healing. She tells us how the food she consumed as a child was completely controlled by her mother, and how that prevented her from learning how to eat intuitively. She also covers the combination of events that led to her developing an eating disorder in midlife. Betsy shares that telling her story in her memoir lifted the weight of her trauma and made her feel empowered and free. She emphasizes that you can recover, as long as you're willing to put in the hard work and deal with the trauma you've experienced. We cover: Why positive comments about someone's body can be damaging, even when they are said with good intentions How eating disorders can affect everyone, no matter their age How shame and stigma can prevent people with eating disorders from sharing their experience with the people around them How freeing and empowering it can be to tell your story How to cope with the difficulties the holidays can bring In Betsy's words: On the shame and stigma surrounding eating disorders: “Like with most mental illnesses, there is so much shame and secrecy, and I think especially when you're older, there's probably even more shame and more secrecy. So, I didn't share it with anybody… I was still trying to understand what this meant for me.” On writing her book: “I decided to write it for two purposes: one was to heal on the deepest possible level from the trauma I had been through and the other was to give hope and inspiration to others because, if I could do this, anybody could do this.” On making her recovery story public: “It has been so freeing having my story out there… It's almost like I was carrying this heavy weight of trauma and emotions and experiences and by writing my memoir, that weight has been lifted.” On how to cope with the holidays during recovery: “The focus needs to be on recognizing how important self-care is… It's okay to protect your mental health, even if the people you have to say ‘no' to don't understand.” You can purchase Betsy's book, The Longest Match: Rallying to Defeat an Eating Disorder in Midlife, on Amazon, through her website, and more! You can also follow Betsy on Instagram (@betsybrennerauthor). Learn more about The Emily Program online or by calling 1-888-364-5977. _ About the podcast: Peace Meal is a podcast hosted by The Emily Program and Veritas Collaborative that covers topics related to eating disorders, body image, and how society may influence our thinking. You can find Peace Meal on Apple Podcasts, Spotify, Stitcher, or Google Podcasts. If you enjoy our show, please rate, review, subscribe, and tell your friends! Are you interested in being a guest on Peace Meal? Email firstname.lastname@example.org for more information.
Around 20% of people have reported a major breakdown in one or more relationships during the pandemic. This includes romantic couples, but also work, family, and friend relationships strained by distance, differing viewpoints, and lack of human connection. But at the same time, 27% said their relationship with their spouse or partner got better! Did the pandemic cause the change or simply reveal what was already there? On this week's podcast, you'll meet a psychiatrist whose private practice and written work focuses on mood and anxiety disorders, and more recently, fixing dysfunctional relationship patterns. Listen & learn: Performer vs. audience dynamics at home The “discovery” process of dysfunction 40/20/40 communication model How to create a plan and agreement for security Links: Dr. Brenner's Site COVID / Relationship Research ABOUT OUR GUESTGrant H. Brenner, MD is a psychiatrist in private practice in New York City. He specializes in treating mood and anxiety disorders. He is an author and editor of the book, Creating Spiritual and Psychological Resilience and the co-author of the new book, Irrelationship. Nutritional Tip of the Week Bowel movement Like the Show? Leave us a Review on iTunes
Brenner says we are not limited, damaged or inadequate. She critiques the self-help movement as perpetuating the idea that we are in need of fixing, and holds the provocative view that nothing needs to be changed or fixed to be happy. She posits that we have the capacity to spontaneously find inner peace by shedding the stories and negative emotions that cause us pain. Gail Brenner, Ph.D. is a clinical psychologist and blogger. She is the author of The End of Self-Help: Discovering Peace and Happiness Right at the Heart of Your Messy, Scary, Brilliant Life (Ananda Press 2015)Interview Date: 6/25/2015 Tags: Gail Brenner, self-help, happiness, searching, curious, curiosity, changing our thoughts, meditation, thought, story, recurrent thoughts, habitual thoughts, conditioned thinking, beliefs, “hello dread”, anxiety, label the emotion, underneath the emotion, couch process, fear, allowing, conditioning, seeking, control, worry about the future, end of resisting, unfolding, Self Help, Personal Transformation, Psychology
From February 20, 2012: Joel Brenner, who served as inspector general of the National Security Agency and as the national counterintelligence executive in the DNI's office, joined Jack Goldsmith to discuss his new book, America the Vulnerable: Inside the New Threat Matrix of Digital Espionage, Crime, and Warfare. Benjamin Wittes reviewed the book here.Support this show http://supporter.acast.com/lawfare. See acast.com/privacy for privacy and opt-out information.
14.11.2021 – Die Publizisten Aleksandra Rybinska (Warschau), Prof. Peter J. Brenner und Markus Vahlefeld diskutieren mit Burkhard Müller-Ullrich über gut ausgestattete Migranten, die nicht wissen, daß zwischen Weißrußland und Deutschland Polen liegt, über die Anmaßungen einer europäischen Gerichtsbarkeit sowie über die Spaltung der Gesellschaft in Geimpfte und Beschimpfte.
Alright FINE we'll stop talking about Brenner and Meiksins-Wood for a minute, but ONLY A MINUTE. Today our fine chunky chaps talk world systems theory in an effort to broaden their horizons and understand how class operates on a systemic level. Or something like that. Reading: The Rise and Future Demise of the World Capitalist System: Concepts for Comparative Analysis (1974) by Immanuel Wallerstein and THE CRITIQUE OF WORLD-SYSTEM THEORY: CLASS RELATIONS OR DIVISION OF LABOR (1984) by Albert Bergesen
Thousands of women across the world suffer from mysterious autoimmune-like symptoms—and many never find a proper diagnosis. I was one of those women—and I was lucky enough to uncover the cause: Breast Implant Illness (BII). After getting my implants out and sharing my story, I remember feeling scared—but I soon discovered a community of women who had shared the same experience. Today, I'm sitting down with two powerhouses in the field of breast implant illness: Dr. Brenner, a board-certified plastic and reconstructive surgeon, and BII patient liaison, Amanda Porta who helps manage his Holistic Breast Team. We discuss their personal experience with BII, progress being made in the industry, and the best ways to support patients who might be experiencing BII symptoms. This is a topic that is deeply personal to me—and I'm so honored to continue this conversation. This episode is a must-listen if you've had plastic surgery, have any medical devices, or if you're considering a future surgery. Follow: instagram.com/sarahannestewart instagram.com/kevinbrennermd More free resources: sarahannestewart.com
Brenner's writing has appeared in Penthouse, Gnosis, New Realities, Technical Photography, Future Life, and in the anthologies Mind In The Waters and Witchcraft Today, vol. IV: Living Between Two Worlds. His photos have appeared in numerous publications, including Time and the Witchcraft Today series from Llewellyn Worldwide. He is a regular contributor to Harbor Style Magazine. Brenner lives in southwest Florida with two dogs and a housemate. He is planning further research on dolphins and writing his next novel, The Jor-Dan Chronicle, about a woman's encounter with an extraterrestrial alien and its effect on her life and subsequent marriages. He is also writing about his childhood experiences growing up in a family that believed in "orgone energy." His "WET GODDESS" website is www.wetgoddess.net*** AND NOW ***The ‘X' Zone TV Channel on SimulTV - www.simultv.comThe ‘X' Zone TV Channel Radio Feed (Free - No Subscription Required) - https://www.spreaker.com/show/xztv-the-x-zone-tv-show-audio The ‘X' Chronicles Newspaper - www.xchroniclesnewspaper.com (Free)To contact Rob McConnell - email@example.com
Featuring perspectives from Drs Richard Furman, Lindsey Roeker and Daniel Lenihan, including the following topics: Introduction (0:00) Chronic Lymphocytic Leukemia (CLL) (1:37) Case: A woman in her early 70s with recurrent CLL and ibrutinib-associated atrial fibrillation — Warren S Brenner, MD (3:30) Case: A woman in her mid-40s with CLL in remission on ibrutinib who experiences ventricular fibrillation — Daniel J Lenihan, MD (29:16) Case: A man in his late 70s with CLL who receives obinutuzumab/venetoclax — Dr Brenner (38:22) Mantle Cell Lymphoma (MCL) (53:25) Novel Agents and Strategies in CLL and MCL (54:46) CME information and select publications
In this episode, we interview the authors of Teaching in Rural Places Thriving in Classrooms, Schools, and Communities, Drs. Amy Price Azano, Devon Brenner, and Ann Schulte regarding the changing demands of education in rural America. They discuss the importance of geography, culture, and change in rural education. They discuss the socio-economic challenges, diversity in rural education, and methods for addressing these unique populations in terms of pedagogy. Link to the book https://doi.org/10.4324/9781003106357 Dr. Amy Price Azano firstname.lastname@example.org Social Media @ruralprof Dr. Devon Brenner email@example.com Social Media @devonbrenner Dr. Ann Schulte firstname.lastname@example.org Social Media @AnnKSchulte1
At the age of twelve, Bryan Brenner's life turned upside down. Suddenly, his parents got divorced, the family filed for bankruptcy, and Bryan's father told him he had to be the man of the house. For Bryan, it was a lesson in how impactful words can be in a negative way, as that sentence filled him with a sense of responsibility that he had no way of fulfilling. Still, Bryan believes some positive things came out of feeling like he needed to grow up fast, like starting a business early on and greater awareness of how he communicates with his family. In this episode, Bryan talks about the need to be thoughtful about our own words and how we absorb the worlds of others. In This Episode: [02:24] This/That with Bryan [04:12] Admitting when you're wrong [06:43] Lessons learned growing up on a farm [07:45] What got Bryan into employee benefits [09:30] The importance of self-awareness and leading yourself [11:05] “What do I want my influence to be?” [13:34] Learning from past mistakes [16:04] The wrong words at the wrong time [22:02] “You can do anything you put your mind to.” [23:17] How Bryan's parents shaped him as a parent [26:28] Words matter Quotes From This Episode: “The more self-aware we are, the more vulnerable we can be, the more genuine we are, the better the outcomes.” “If a human being feels known for who they truly are and they feel loved in that, they can do just about anything and work through just about anything.” “Be careful with how you absorb other people's words because often they don't know how they might impact you and you have to be responsible for that yourself.”
Digital Technology has not yet found its way into the chemical industry on a broad scale. Victoria Meyer's guest today, Sebastian Brenner, explains why that needs to change. Sebastian is the Managing Director of CheMondis, the leading digital marketplace for chemicals in Europe, with over 7,000 companies participating. Join the conversation as Sebastian discusses how digital technology handles repetitive ordering, freeing up time for people to engage in more critical tasks. Despite the massive benefit digitalization brings, personal interaction will never go away. Chemical products require a deep understanding that only a human being can give. Tune in and upgrade your digital technology!Love the show? Subscribe, rate, review, and share! http://www.thechemicalshow.com/
Leon Brenner, Author of The Autistic Subject: on the Threshold of Language joined us again this week to pick up on a discussion of the drive circuit, the synthetic other, and the various modalities of the rim. https://www.palgrave.com/gp/book/9783030507145 https://leonbrenner.com/ https://twitter.com/leonbrennercom?lang=en Support us on Patreon: https://www.patreon.com/muhh Twitter: @unconscioushh Instagram: @unconscioushh
Producer/Host: C.J. Walke -Karen Washington – “Food Justice is More Than Growing Food and Feeding People” -Stacy Brenner – Farm Viability Through Land Justice and Farmworker Rights -2021 CGCF Keynote addresses Speakers: Karen Washington, Rise & Root Farm, Black Urban Growers Stacy Brenner, Broadturn Farm, Scarborough, ME About the hosts: C.J. Walke has been involved in Maine agriculture for over 20 years and has worked in numerous capacities for the Maine Organic Farmers and Gardeners Association (MOFGA) starting in 2006. Since 2012, C.J. has worked as farm manager for College of the Atlantic’s Peggy Rockefeller Farms in Bar Harbor, Maine, where he works with students to grow organic fruits, vegetables and livestock products. He holds degrees in park management/environment education and library science. Common Ground Radio debuted in June of 2010 and C.J. has been the show’s host since 2014. Holli Cederholm has been involved in organic agriculture since 2005 when she first apprenticed on a small farm. She has worked on organic farms in Maine, Vermont, Connecticut, Scotland and Italy and, in 2010, founded a small farm focused on celebrating open-pollinated and heirloom vegetables. As the former manager of a national nonprofit dedicated to organic seed growers, she authored a peer-reviewed handbook on GMO avoidance strategies for seed growers. Holli has also been a steward at Forest Farm, the iconic homestead of “The Good Life” authors Helen and Scott Nearing; a host of “The Farm Report” on Heritage Radio Network; and a long-time contributor for The Maine Organic Farmer & Gardener, which she now edits in her role as content creator and editor at MOFGA. The post Common Ground Radio 10/14/21: Keynote Addresses from the 2021 Common Ground Country Fair – Karen Washington and Stacy Brenner first appeared on WERU 89.9 FM Blue Hill, Maine Local News and Public Affairs Archives.
Raspberries, ellagic acid reveal benefits in two studies Oregon State University, October 1, 2021. Articles that appeared recently in the Journal of Berry Research report that raspberries and compounds present in the fruit could help support healthy body mass and motor function, including balance, coordination and strength. In one study, Neil Shay and colleagues at Oregon State University fed mice a high fat, high sugar diet plus one of the following: raspberry juice concentrate, raspberry puree concentrate, raspberry fruit powder, raspberry seed extract, ellagic acid (a polyphenol that occurs in a relatively high amount in raspberries), raspberry ketone, or a combination of raspberry ketone and ellagic acid. Additional groups of animals received a high fat, high sugar diet alone or a low fat diet. While mice that received the high fat and sugar diet alone experienced a significant increase in body mass, the addition of raspberry juice concentrate, raspberry puree concentrate or ellagic acid plus raspberry ketone helped prevent this effect. Of note, mice that received raspberry juice concentrate experienced gains similar to those of animals given a low fat diet. "We hope that the findings from this study can help guide the design of future clinical trials," Dr Shay stated. In another study, Barbara Shukitt-Hale, PhD, and her associates at Tufts University's Human Nutrition Research Center on Aging gave 19 month old rats a control diet or a diet enhanced with raspberry extract for 11 weeks. Psychomotor behavior was assessed during week 7 and cognitive testing was conducted during weeks 9-10. Animals that received raspberry performed better on psychomotor coordination and balance, and had better muscle tone, strength and stamina than those that received a control diet. "These results may have important implications for healthy aging," stated Dr Shukitt-Hale. "While further research in humans is necessary, animal model studies are helpful in identifying deficits associated with normal aging." Massage doesn't just make muscles feel better, it makes them heal faster and stronger Harvard University, October 6, 2021 Massage has been used to treat sore, injured muscles for more than 3,000 years, and today many athletes swear by massage guns to rehabilitate their bodies. But other than making people feel good, do these "mechanotherapies" actually improve healing after severe injury? According to a new study from researchers at Harvard's Wyss Institute for Biologically Inspired Engineering and John A. Paulson School of Engineering and Applied Sciences (SEAS), the answer is "yes." Using a custom-designed robotic system to deliver consistent and tunable compressive forces to mice's leg muscles, the team found that this mechanical loading (ML) rapidly clears immune cells called neutrophils out of severely injured muscle tissue. This process also removed inflammatory cytokinesreleased by neutrophils from the muscles, enhancing the process of muscle fiber regeneration. The research is published in Science Translational Medicine. "Lots of people have been trying to study the beneficial effects of massage and other mechanotherapies on the body, but up to this point it hadn't been done in a systematic, reproducible way. Our work shows a very clear connection between mechanical stimulation and immune function. This has promise for regenerating a wide variety of tissues including bone, tendon, hair, and skin, and can also be used in patients with diseases that prevent the use of drug-based interventions," said first author Bo Ri Seo, Ph.D., who is a Postdoctoral Fellow in the lab of Core Faculty member Dave Mooney, Ph.D. at the Wyss Institute and SEAS. Seo and her coauthors started exploring the effects of mechanotherapy on injured tissues in mice several years ago, and found that it doubled the rate of muscle regeneration and reduced tissue scarring over the course of two weeks. Excited by the idea that mechanical stimulation alone can foster regeneration and enhance muscle function, the team decided to probe more deeply into exactly how that process worked in the body, and to figure out what parameters would maximize healing. They teamed up with soft robotics experts in the Harvard Biodesign Lab, led by Wyss Associate Faculty member Conor Walsh, Ph.D., to create a small device that used sensors and actuators to monitor and control the force applied to the limb of a mouse. " The device we created allows us to precisely control parameters like the amount and frequency of force applied, enabling a much more systematic approach to understanding tissue healing than would be possible with a manual approach," said co-second author Christopher Payne, Ph.D., a former Postdoctoral Fellow at the Wyss Institute and the Harvard Biodesign Lab who is now a Robotics Engineer at Viam, Inc. Once the device was ready, the team experimented with applying force to mice's leg muscles via a soft silicone tip and used ultrasound to get a look at what happened to the tissue in response. They observed that the muscles experienced a strain of between 10-40%, confirming that the tissues were experiencing mechanical force. They also used those ultrasound imaging data to develop and validate a computational model that could predict the amount of tissue strain under different loading forces. They then applied consistent, repeated force to injured muscles for 14 days. While both treated and untreated muscles displayed a reduction in the amount of damaged muscle fibers, the reduction was more pronounced and the cross-sectional area of the fibers was larger in the treated muscle, indicating that treatment had led to greater repair and strength recovery. The greater the force applied during treatment, the stronger the injured muscles became, confirming that mechanotherapy improves muscle recovery after injury. But how? Evicting neutrophils to enhance regeneration To answer that question, the scientists performed a detailed biological assessment, analyzing a wide range of inflammation-related factors called cytokines and chemokines in untreated vs. treated muscles. A subset of cytokines was dramatically lower in treated muscles after three days of mechanotherapy, and these cytokines are associated with the movement of immune cells called neutrophils, which play many roles in the inflammation process. Treated muscles also had fewer neutrophils in their tissue than untreated muscles, suggesting that the reduction in cytokines that attract them had caused the decrease in neutrophil infiltration. The team had a hunch that the force applied to the muscle by the mechanotherapy effectively squeezed the neutrophils and cytokines out of the injured tissue. They confirmed this theory by injecting fluorescent molecules into the muscles and observing that the movement of the molecules was more significant with force application, supporting the idea that it helped to flush out the muscle tissue. To pick apart what effect the neutrophils and their associated cytokines have on regenerating muscle fibers, the scientists performed in vitro studies in which they grew muscle progenitor cells (MPCs) in a medium in which neutrophils had previously been grown. They found that the number of MPCs increased, but the rate at which they differentiated (developed into other cell types) decreased, suggesting that neutrophil-secreted factors stimulate the growth of muscle cells, but the prolonged presence of those factors impairs the production of new muscle fibers. "Neutrophils are known to kill and clear out pathogens and damaged tissue, but in this study we identified their direct impacts on muscle progenitor cell behaviors," said co-second author Stephanie McNamara, a former Post-Graduate Fellow at the Wyss Institute who is now an M.D.-Ph.D. student at Harvard Medical School (HMS). "While the inflammatory response is important for regeneration in the initial stages of healing, it is equally important that inflammation is quickly resolved to enable the regenerative processes to run its full course." Seo and her colleagues then turned back to their in vivo model and analyzed the types of muscle fibers in the treated vs. untreated mice 14 days after injury. They found that type IIX fibers were prevalent in healthy muscle and treated muscle, but untreated injured muscle contained smaller numbers of type IIX fibers and increased numbers of type IIA fibers. This difference explained the enlarged fiber size and greater force production of treated muscles, as IIX fibers produce more force than IIA fibers. Finally, the team homed in on the optimal amount of time for neutrophil presence in injured muscle by depleting neutrophils in the mice on the third day after injury. The treated mice's muscles showed larger fiber size and greater strength recovery than those in untreated mice, confirming that while neutrophils are necessary in the earliest stages of injury recovery, getting them out of the injury site early leads to improved muscle regeneration. "These findings are remarkable because they indicate that we can influence the function of the body's immune system in a drug-free, non-invasive way," said Walsh, who is also the Paul A. Maeder Professor of Engineering and Applied Science at SEAS and whose group is experienced in developing wearable technology for diagnosing and treating disease. "This provides great motivation for the development of external, mechanical interventions to help accelerate and improve muscle and tissue healing that have the potential to be rapidly translated to the clinic." The team is continuing to investigate this line of research with multiple projects in the lab. They plan to validate this mechanotherpeutic approach in larger animals, with the goal of being able to test its efficacy on humans. They also hope to test it on different types of injuries, age-related muscle loss, and muscle performance enhancement. "The fields of mechanotherapy and immunotherapy rarely interact with each other, but this work is a testament to how crucial it is to consider both physical and biological elements when studying and working to improve human health," said Mooney, who is the corresponding author of the paper and the Robert P. Pinkas Family Professor of Bioengineering at SEAS. "The idea that mechanics influence cell and tissue function was ridiculed until the last few decades, and while scientists have made great strides in establishing acceptance of this fact, we still know very little about how that process actually works at the organ level. This research has revealed a previously unknown type of interplay between mechanobiology and immunology that is critical for muscle tissue healing, in addition to describing a new form of mechanotherapy that potentially could be as potent as chemical or gene therapies, but much simpler and less invasive," said Wyss Founding Director Don Ingber, M.D., Ph.D., who is also the Judah Folkman Professor of Vascular Biology at (HMS) and the Vascular Biology Program at Boston Children's Hospital, as well as Professor of Bioengineering at SEAS. Vitamin E could help protect older men from pneumonia University of Helsinki (Finland), October 7 2021. An article that appeared in Clinical Interventions in Aging reported a protective role for vitamin E against pneumonia in older men. For the current investigation, Dr Harri Hemilä of the University of Helsinki, Finland analyzed data from the Alpha-Tocopherol Beta-Carotene (ATBC) Cancer Prevention Study conducted in Finland. The trial included 29,133 men between the ages of 50 to 69 years who smoked at least five cigarettes daily upon enrollment. Participants received alpha tocopherol (vitamin E), beta carotene, both supplements, or a placebo for five to eight years. The current study was limited to 7,469 ATBC participants who started smoking at age 21 or older. Among this group, supplementation with vitamin E was associated with a 35% lower risk of developing pneumonia in comparison with those who did not receive the vitamin. Light smokers who engaged in leisure time exercise had a 69% lower risk compared with unsupplemented members of this subgroup. The risk in this subgroup of developing pneumonia by age 74 was 12.9%. Among the one-third of the current study's population who quit smoking for a median period of two years, there was a 72% lower risk of pneumonia in association with vitamin E supplementation. In this group, exercisers who received vitamin E experienced an 81% lower pneumonia risk. Dr Hemilä observed that the benefit for vitamin E in this study was strongest for older subjects—a group at higher risk of pneumonia. "The current analysis of individual-level data suggests that trials on vitamin E and pneumonia on nonsmoking elderly males are warranted," he concluded. Toxic fatty acids to blame for brain cell death after injury New York University, October 7, 2021 Cells that normally nourish healthy brain cells called neurons release toxic fatty acids after neurons are damaged, a new study in rodents shows. This phenomenon is likely the driving factor behind most, if not all, diseases that affect brain function, as well as the natural breakdown of brain cells seen in aging, researchers say. Previous research has pointed to astrocytes—a star-shaped glial cell of the central nervous system—as the culprits behind cell death seen in Parkinson's disease and dementia, among other neurodegenerative diseases. While many experts believed that these cells released a neuron-killing molecule to "clear away" damaged brain cells, the identity of this toxin has until now remained a mystery. Led by researchers at NYU Grossman School of Medicine, the new investigation provides what they say is the first evidence that tissue damage prompts astrocytes to produce two kinds of fats, long-chain saturated free fatty acids and phosphatidylcholines. These fats then trigger cell death in damaged neurons, the electrically active cells that send messages throughout nerve tissue. Publishing Oct. 6 in the journal Nature, the study also showed that when researchers blocked fatty acid formation in mice, 75 percent of neurons survived compared with 10 percent when the fatty acids were allowed to form. The researchers' earlier work showed that brain cells continued to function when shielded from astrocyte attacks. "Our findings show that the toxic fatty acids produced by astrocytes play a critical role in brain cell death and provide a promising new target for treating, and perhaps even preventing, many neurodegenerative diseases," says study co-senior author Shane Liddelow, Ph.D. Liddelow, an assistant professor in the Department of Neuroscience and Physiology at NYU Langone Health, adds that targeting these fats instead of the cells that produce them may be a safer approach to treating neurodegenerative diseasesbecause astrocytes feed nerve cells and clear away their waste. Stopping them from working altogether could interfere with healthy brain function. Although it remains unclear why astrocytes produce these toxins, it is possible they evolved to destroy damaged cells before they can harm their neighbors, says Liddelow. He notes that while healthy cells are not harmed by the toxins, neurons become susceptible to the damaging effects when they are injured, mutated, or infected by prions, the contagious, misfolded proteins that play a major role in mad cow disease and similar illnesses. Perhaps in chronic diseases like dementia, this otherwise helpful process goes off track and becomes a problem, the study authors say. For the investigation, researchers analyzed the molecules released by astrocytes collected from rodents. They also genetically engineered some groups of mice to prevent the normal production of the toxic fats and looked to see whether neuron death occurred after an acute injury. "Our results provide what is likely the most detailed molecular map to date of how tissue damage leads to brain cell death, enabling researchers to better understand why neurons die in all kinds of diseases," says Liddelow, also an assistant professor in the Department of Ophthalmology at NYU Langone. Liddelow cautions that while the findings are promising, the genetic techniques used to block the enzyme that produces toxic fatty acids in mice are not ready for use in humans. As a result, the researchers next plan is to explore safe and effective ways to interfere with the release of the toxins in human patients. Liddelow and his colleagues had previously shown these neurotoxic astrocytes in the brains of patients with Parkinson's, Huntington's disease, and multiple sclerosis, among other diseases. Clinical trial for nicotinamide riboside: Vitamin safely boosts levels of important cell metabolite linked to multiple health benefits University of Iowa Health Care, October 3, 2021 In the first controlled clinical trial of nicotinamide riboside (NR), a newly discovered form of Vitamin B3, researchers have shown that the compound is safe for humans and increases levels of a cell metabolite that is critical for cellular energy production and protection against stress and DNA damage. Studies in mice have shown that boosting the levels of this cell metabolite -- known as NAD+ -- can produce multiple health benefits, including resistance to weight gain, improved control of blood sugar and cholesterol, reduced nerve damage, and longer lifespan. Levels of NAD+ diminish with age, and it has been suggested that loss of this metabolite may play a role in age-related health decline. These findings in animal studies have spurred people to take commercially available NR supplements designed to boost NAD+. However, these over-the-counter supplements have not undergone clinical trials to see if they work in people. The new research, reported in the journal Nature Communications, was led by Charles Brenner, PhD, professor and Roy J. Carver Chair of Biochemistry at the University of Iowa Carver College of Medicine in collaboration with colleagues at Queens University Belfast and ChromaDex Corp. (NASDAQ: CDXC), which supplied the NR used in the trial. Brenner is a consultant for ChromaDex. He also is co-founder and Chief Scientific Adviser of ProHealthspan, which sells NR supplements under the trade name Tru NIAGEN®. The human trial involved six men and six women, all healthy. Each participant received single oral doses of 100 mg, 300 mg, or 1,000 mg of NR in a different sequence with a seven-day gap between doses. After each dose, blood and urine samples were collected and analyzed by Brenner's lab to measure various NAD+ metabolites in a process called metabolomics. The trial showed that the NR vitamin increased NAD+ metabolism by amounts directly related to the dose, and there were no serious side effects with any of the doses. "This trial shows that oral NR safely boosts human NAD+ metabolism," Brenner says. "We are excited because everything we are learning from animal systems indicates that the effectiveness of NR depends on preserving and/or boosting NAD+ and related compounds in the face of metabolic stresses. Because the levels of supplementation in mice that produce beneficial effects are achievable in people, it appears than health benefits of NR will be translatable to humans safely." The next step will be to study the effect of longer duration NR supplementation on NAD+ metabolism in healthy adults, but Brenner also has plans to test the effects of NR in people with diseases and health conditions, including elevated cholesterol, obesity and diabetes, and people at risk for chemotherapeutic peripheral neuropathy. Prior to the formal clinical trial, Brenner conducted a pilot human study -- on himself. In 2004, he had discovered that NR is a natural product found in milk and that there is pathway to convert NR to NAD+ in people. More than a decade of research on NR metabolic pathways and health effects in mice and rats had convinced him that NR supplementation had real promise to improve human health and wellness. After consulting with UI's institutional review board, he conducted an experiment in which he took 1 gram of NR once a day for seven days, and his team analyzed blood and urine samples using mass spectrometry. The experiment showed that Brenner's blood NAD+ increased by about 2.7 times. In addition, though he reported immediate sensitivity to flushing with the related compound niacin, he did not experience any side effects taking NR. The biggest surprise from his metabolomic analysis was an increase in a metabolite called NAAD, which was multiplied by 45 times, from trace levels to amounts in the micromolar range that were easily detectable. "While this was unexpected, I thought it might be useful," Brenner says. "NAD+ is an abundant metabolite and it is sometimes hard to see the needle move on levels of abundant metabolites. But when you can look at a low-abundance metabolite that goes from undetectable to easily detectable, there is a great signal to noise ratio, meaning that NAAD levels could be a useful biomarker for tracking increases in NAD+ in human trials." Brenner notes this was a case of bidirectional translational science; having learned something from the initial human experiment, his team was able to return to laboratory mice to explore the unexpected NAAD finding in more detail. Brenner's mouse study showed that NAAD is formed from NR and confirmed that NAAD levels are a strong biomarker for increased NAD+ metabolism. The experiments also revealed more detail about NAD+ metabolic pathways. In particular, the researchers compared the ability of all three NAD+ precursor vitamins -- NR, niacin, and nicotinamide -- to boost NAD+ metabolism and stimulate the activity of certain enzymes, which have been linked to longevity and healthbenefits. The study showed for the first time that oral NR is superior to nicotinamide, which is better than niacin in terms of the total amount of NAD+ produced at an equivalent dose. NR was also the best of the three in stimulating the activity of sirtuin enzymes. However, in this case, NR was the best at stimulating sirtuin-like activities, followed by niacin, followed by nicotinamide. The information from the mouse study subsequently helped Brenner's team design the formal clinical trial. In addition to showing that NR boosts NAD+ in humans without adverse effects, the trial confirmed that NAAD is a highly sensitive biomarker of NAD+ supplementation in people. "Now that we have demonstrated safety in this small clinical trial, we are in a position to find out if the health benefits that we have seen in animals can be reproduced in people," says Brenner, who also is co-director of the Obesity Research and Education Initiative, professor of internal medicine, and a member of the Fraternal Order of Eagles Diabetes Research Center at the UI. Protecting the ozone layer is delivering vast health benefits Montreal Protocol will spare Americans from 443 million skin cancer cases National Center for Atmospheric Research, October 7, 2021 An international agreement to protect the ozone layer is expected to prevent 443 million cases of skin cancer and 63 million cataract cases for people born in the United States through the end of this century, according to new research. The research team, by scientists at the National Center for Atmospheric Research (NCAR), ICF Consulting, and U.S. Environmental Protection Agency (EPA), focused on the far-reaching impacts of a landmark 1987 treaty known as the Montreal Protocol and later amendments that substantially strengthened it. The agreement phased out the use of chemicals such as chlorofluorocarbons (CFCs) that destroy ozone in the stratosphere. Stratospheric ozone shields the planet from harmful levels of the Sun's ultraviolet (UV) radiation, protecting life on Earth. To measure the long-term effects of the Montreal Protocol, the scientists developed a computer modeling approach that enabled them to look to both the past and the future by simulating the treaty's impact on Americans born between 1890 and 2100. The modeling revealed the treaty's effect on stratospheric ozone, the associated reductions in ultraviolet radiation, and the resulting health benefits. In addition to the number of skin cancer and cataract cases that were avoided, the study also showed that the treaty, as most recently amended, will prevent approximately 2.3 million skin cancer deaths in the U.S. “It's very encouraging,” said NCAR scientist Julia Lee-Taylor, a co-author of the study. “It shows that, given the will, the nations of the world can come together to solve global environmental problems.” The study, funded by the EPA, was published in ACS Earth and Space Chemistry. NCAR is sponsored by the National Science Foundation. Mounting concerns over the ozone layer Scientists in the 1970s began highlighting the threat to the ozone layer when they found that CFCs, used as refrigerants and in other applications, release chlorine atoms in the stratosphere that set off chemical reactions that destroy ozone. Concerns mounted the following decade with the discovery of an Antarctic ozone hole. The loss of stratospheric ozone would be catastrophic, as high levels of UV radiation have been linked to certain types of skin cancer, cataracts, and immunological disorders. The ozone layer also protects terrestrial and aquatic ecosystems, as well as agriculture. Policy makers responded to the threat with the 1987 Montreal Protocol on Substances that Deplete the Ozone Layer, in which nations agreed to curtail the use of certain ozone-destroying substances. Subsequent amendments strengthened the treaty by expanding the list of ozone-destroying substances (such as halons and hydrochlorofluorocarbons, or HCFCs) and accelerating the timeline for phasing out their use. The amendments were based on Input from the scientific community, including a number of NCAR scientists, that were summarized in quadrennial Ozone Assessment reports. To quantify the impacts of the treaty, the research team built a model known as the Atmospheric and Health Effects Framework. This model, which draws on various data sources about ozone, public health, and population demographics, consists of five computational steps. These simulate past and future emissions of ozone-destroying substances, the impacts of those substances on stratospheric ozone, the resulting changes in ground-level UV radiation, the U.S. population's exposure to UV radiation, and the incidence and mortality of health effects resulting from the exposure. The results showed UV radiation levels returning to 1980 levels by the mid-2040s under the amended treaty. In contrast, UV levels would have continued to increase throughout this century if the treaty had not been amended, and they would have soared far higher without any treaty at all. Even with the amendments, the simulations show excess cases of cataracts and various types of skin cancer beginning to occur with the onset of ozone depletion and peaking decades later as the population exposed to the highest UV levels ages. Those born between 1900 and 2040 experience heightened cases of skin cancer and cataracts, with the worst health outcomes affecting those born between about 1950 and 2000. However, the health impacts would have been far more severe without the treaty, with cases of skin cancer and cataracts rising at an increasingly rapid rate through the century. “We peeled away from disaster,” Lee-Taylor said. “What is eye popping is what would have happened by the end of this century if not for the Montreal Protocol. By 2080, the amount of UV has tripled. After that, our calculations for the health impacts start to break down because we're getting so far into conditions that have never been seen before.” The research team also found that more than half the treaty's health benefits could be traced to the later amendments rather than the original 1987 Montreal Protocol. Overall, the treaty prevented more than 99% of potential health impacts that would have otherwise occurred from ozone destruction. This showed the importance of the treaty's flexibility in adjusting to evolving scientific knowledge, the authors said. The researchers focused on the U.S. because of ready access to health data and population projections. Lee-Taylor said that the specific health outcomes in other countries may vary, but the overall trends would be similar. “The treaty had broad global benefits,” she said. What is Boron? The trace mineral boron provides profound anti-cancer effects, in addition to maintaining stronger bones. Life Extension, September 2021 Boron is a trace mineral found in the earth's crust and in water. Its importance in human health has been underestimated. Boron has been shown to have actions against specific types of malignancies, such as: Cervical cancer: The country Turkey has an extremely low incidence of cervical cancer, and scientists partially attribute this to its boron-rich soil.1 When comparing women who live in boron-rich regions versus boron-poor regions of Turkey, not a single woman living in the boron-rich regions had any indication of cervical cancer.2(The mean dietary intake of boron for women in this group was 8.41 mg/day.) Boron interferes with the life cycle of the human papillomavirus (HPV), which is a contributing factor in approximately 95% of all cervical cancers.1 Considering that HPV viruses are increasingly implicated in head and neck cancers,3,4 supplementation with this ultra-low-cost mineral could have significant benefits in protecting against this malignancy that is increasing in prevalence. Lung cancer: A study conducted at the University of Texas MD Anderson Cancer Center between 1995 and 2005 found that increased boron intake was associated with a lower risk of lung cancer in postmenopausal women who were taking hormone replacement therapy. Prostate cancer: Studies point to boron's ability to inhibit the growth and spread of prostate cancer cells. In one study, when mice were exposed to boric acid, their tumors shrank by as much as 38%.6 One analysis found that increased dietary boron intake was associated with a decreased risk of prostate cancer.7 Several human and animal studies have confirmed the important connection between boron and bone health. Boron prevents calcium loss,8 while also alleviating the bone problems associated with magnesium and vitamin D deficiency.9 All of these nutrients help maintain bone density. A study in female rats revealed the harmful effects a deficiency in boron has on bones, including:10 Decreased bone volume fraction, a measure of bone strength, Decreased thickness of the bone's spongy inner layer, and Decreased maximum force needed to break the femur. And in a study of post-menopausal women, supplementation with3 mg of boron per day prevented calcium loss and bone demineralization by reducing urinary excretion of both calcium and magnesium.8 In addition to its bone and anti-cancer benefits, there are nine additional reasons boron is an important trace mineral vital for health and longevity. It has been shown to:1 Greatly improve wound healing, Beneficially impact the body's use of estrogen, testosterone, and vitamin D, Boost magnesium absorption, Reduce levels of inflammatory biomarkers, such as high-sensitivity C-reactive protein (hs-CRP) and tumor necrosis factor α (TNF-α), Raise levels of antioxidant enzymes, such as superoxide dismutase (SOD), catalase, and glutathione peroxidase, Protect against pesticide-induced oxidative stress and heavy-metal toxicity, Improve the brain's electrical activity, which may explain its benefits for cognitive performance, and short-term memory in the elderly, Influence the formation and activity of key biomolecules, such as S-adenosyl methionine (SAM-e) and nicotinamide adenine dinucleotide (NAD+), and Potentially help ameliorate the adverse effects of traditional chemotherapeutic agents. Because the amount of boron varies in the soil, based on geographical location, obtaining enough boron through diet alone can be difficult. Supplementing with low-cost boron is an effective way to maintain adequate levels of this overlooked micronutrient.
Maia Brenner (AI Specialist & Head of Business Development @ Tryolabs) shares the fundamentals to begin your company's AI/ML journey! We cover the most common challenges & pitfalls eng leaders face when investing in AI, how to understand feasibility/impact & ROI of different AI/ML initiatives, how to build your AI roadmap, how to break down massive AI/ML projects into small experiments, and how to accelerate different phases of your AI/ML strategy with partners like Tryolabs. ABOUT MAIA BRENNER Maia Brenner is a passionate data scientist and economist with strong programming skills, a mathematical and statistical background, and work experience in consulting and the public sector. As an AI Specialist at Tryolabs she helps clients maximize the full potential of data science and machine learning to solve their business problems. Maia's experience in the consulting industry covers several projects related to demand forecasting, price optimization, customer segmentation, and natural language processing applications, among others. As a technical consultant, she has helped design and develop AI solutions for companies from several different industries such as Retail, Finance, Pharma, Logistics, Transportation, Hospitality, Education, and more. She is also a professor in several universities and enjoys working on initiatives of AI4SocialGood. She has helped in the application of Machine Learning to improve the Public Education sector and is involved in Gender Inequality research groups. SHOW NOTES The origin story behind Tryolabs (2:33) Common AI/ML challenges Tryolabs helps solve (5:48) Most painful problems with building AI capabilities (7:50) What are the fundamentals to build an AI organization? (10:11) How do you integrate AI/ML into your core business? (12:42) What problems can (or can't) be solved with AI/ML? (15:18) How Tryolabs helps companies to identify specific AI/ML use cases (16:59) Common pitfalls when investing in & integrating AI/ML into your company (18:19) How to start small & experiment with AI/ML solutions (20:14) How Tryolabs scopes & iterates their AI/ML projects (24:42) Metrics, KPIs & other ways to determine feasibility, impact & ROI of your AI/ML project (26:53) How to build an AI/ML roadmap for your organization (30:34) How Tryolabs accelerates building your AI organization (34:28) --- Ready to own your AI Strategy? Learn more about Tryolabs HERE: https://bit.ly/39QpNoH --- Send in a voice message: https://anchor.fm/engineeringleadership/message
How can we best understand ethnic armed organizations on the borderlands of Myanmar? Why did the Karen embrace the military-initiated peace process in 2012, shortly after the Kachin had rejected ceasefire proposals? How can ethnographic fieldwork inform studies of insurgent movements? And what does the February 2021 military coup mean for the future of ethnic conflicts in Myanmar In this wide-ranging conversation, David Brenner – a lecturer in global insecurities at the University of Sussex – discusses these questions with Duncan McCargo, director of the Nordic Institute of Asian Studies and professor of political science at the University of Copenhagen. He makes the case for an understanding of insurgent groups based on their specific internal political dynamics, which cannot be readily reduced to rational, economics-related incentives and obstacles. Rebel Politics: A Political Sociology of Armed Struggle in Myanmar's Borderlands (Cornell UP, 2019) analyzes the changing dynamics of the civil war in Myanmar, one of the most entrenched armed conflicts in the world. Since 2011, a national peace process has gone hand-in-hand with escalating ethnic conflict. The Karen National Union (KNU), previously known for its uncompromising stance against the central government of Myanmar, became a leader in the peace process after it signed a ceasefire in 2012. Meanwhile, the Kachin Independence Organization (KIO) returned to the trenches in 2011 after its own seventeen-year-long ceasefire broke down. To understand these puzzling changes, Brenner conducted ethnographic fieldwork among the KNU and KIO, analyzing the relations between rebel leaders, their rank-and-file, and local communities in the context of wider political and geopolitical transformations. Drawing on political sociology perspectives, Rebel Politics explains how revolutionary elites capture and lose legitimacy within their own movements and how these internal contestations drive the strategies of rebellion in unforeseen ways. Brenner presents a novel perspective that contributes to our understanding of contemporary politics in Southeast Asia, and to the study of conflict, peace and security, by highlighting the hidden social dynamics and everyday practices of political violence, ethnic conflict, rebel governance and borderland politics. Interested in this topic? You might also like these recent NBN podcasts: Karen Sanctuaries: Memory, Biodiversity and Political Sovereignty Ruth Streicher, "Uneasy Military Encounters: The Imperial Politics of Counterinsurgency in Southern Thailand" (Cornell UP, 2020) Duncan McCargo is an eclectic, internationalist political scientist and literature buff: his day job is directing the Nordic Institute of Asian Studies at the University of Copenhagen. Learn more here, here, here, and here. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network
How can we best understand ethnic armed organizations on the borderlands of Myanmar? Why did the Karen embrace the military-initiated peace process in 2012, shortly after the Kachin had rejected ceasefire proposals? How can ethnographic fieldwork inform studies of insurgent movements? And what does the February 2021 military coup mean for the future of ethnic conflicts in Myanmar In this wide-ranging conversation, David Brenner – a lecturer in global insecurities at the University of Sussex – discusses these questions with Duncan McCargo, director of the Nordic Institute of Asian Studies and professor of political science at the University of Copenhagen. He makes the case for an understanding of insurgent groups based on their specific internal political dynamics, which cannot be readily reduced to rational, economics-related incentives and obstacles. Rebel Politics: A Political Sociology of Armed Struggle in Myanmar's Borderlands (Cornell UP, 2019) analyzes the changing dynamics of the civil war in Myanmar, one of the most entrenched armed conflicts in the world. Since 2011, a national peace process has gone hand-in-hand with escalating ethnic conflict. The Karen National Union (KNU), previously known for its uncompromising stance against the central government of Myanmar, became a leader in the peace process after it signed a ceasefire in 2012. Meanwhile, the Kachin Independence Organization (KIO) returned to the trenches in 2011 after its own seventeen-year-long ceasefire broke down. To understand these puzzling changes, Brenner conducted ethnographic fieldwork among the KNU and KIO, analyzing the relations between rebel leaders, their rank-and-file, and local communities in the context of wider political and geopolitical transformations. Drawing on political sociology perspectives, Rebel Politics explains how revolutionary elites capture and lose legitimacy within their own movements and how these internal contestations drive the strategies of rebellion in unforeseen ways. Brenner presents a novel perspective that contributes to our understanding of contemporary politics in Southeast Asia, and to the study of conflict, peace and security, by highlighting the hidden social dynamics and everyday practices of political violence, ethnic conflict, rebel governance and borderland politics. Interested in this topic? You might also like these recent NBN podcasts: Karen Sanctuaries: Memory, Biodiversity and Political Sovereignty Ruth Streicher, "Uneasy Military Encounters: The Imperial Politics of Counterinsurgency in Southern Thailand" (Cornell UP, 2020) Duncan McCargo is an eclectic, internationalist political scientist and literature buff: his day job is directing the Nordic Institute of Asian Studies at the University of Copenhagen. Learn more here, here, here, and here. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/sociology
Calling all health nerds, biohackers and beauty aficionados! In this fascinating episode, leading functional medicine expert Dr. Will Cole, sits down with Dr. Charles Brenner, a research pioneer in the area of nicotinamide adenine dinucleotide (NAD+). NAD+ is fundamental to the creation of energy in every cell of your body. NAD+ regulates pivotal cellular processes that are key to looking and feeling our best. Getting your NAD+ levels optimized can help you maintain vibrant energy levels and that youthful glow. Tune in to learn the exciting science behind NAD+ and discover why it is so vitally important to the cellular health of our bodies. Listen in as Dr. Brenner discusses the best ways to boost your NAD+ levels naturally. Learn more: www.drwillcole.com/podcast Redefine aging today by visiting Tru Niagen Produced by Dear Media
In this episode, Karin is joined by Betsy Brenner, author, high school tennis coach, eating disorder recovery speaker, peer support mentor, and support group co-leader. Betsy's recovery story has been shared widely on many eating disorders blogs and websites. She recently published her memoir, “The Longest Match: Rallying to Defeat an Eating Disorder in Mid-Life”Join Karin and Betsy as they discuss the components of an eating disorder “perfect storm,” coping with the reemergence of buried, internalized experiences, the importance of self-care, vulnerability as an acceptable and necessary practice, changing the role of movement from obsessive to healing, the challenges of meeting one's needs, the deeper level of healing that comes with sharing one's story, the evolution of Betsy's recovery story, the process of publishing her memoir, “The Longest Match: Rallying to Defeat an Eating Disorder in Mid-Life,” and much more.CONNECT WITH BETSY:• Learn more about Betsy by visiting betsybrenner.com• Follow Betsy on Facebook and Instagram• Purchase a copy of “The Longest Match: Rallying to Defeat an Eating Disorder in Mid-Life” on Amazon• Read the book excerpt “Divorce: The End of Innocence and its Impact on the Elementary School Years“• View Betsy's recent speaking events• Read Betsy's featured publications and writing＿＿＿＿＿＿＿＿＿＿＿＿＿＿＿＿＿＿＿＿ Apply to be a guest on the show here!
Kevin Brenner: How To Find A Group Of Like-Minded Individuals Meet Kevin, an active real estate professional focusing on the acquisition, rehab, management, and sale of multifamily properties. He currently owns and manages 9 cash flowing units out-of-state worth approximately $795,000. He also manages Short Term Rentals in the local Washington DC market. He is also the founder and CEO of Nimbus Capital Investment Co. the first and only Fund of Funds dedicated to helping Accredited Millennials create, nurture, and grow wealth through large commercial multifamily real estate ventures in emerging markets nationwide... Wealth Creation for the Millennial Generation! What You Will Discover: [1:18] Money Is Not Currency, Social Capital Is A Real Thing And Extremely Powerful [18:37] There's No Shortage Of Undercapitalized Syndicators In Today's Market [28:48] Simplicity Is Really Important In Business [34:20] Raising Capital, It's Only Difficult Until It's No Longer Difficult [37:15] Being A Fund Manager Is The Most Lucrative Career [40:49] The New Currency In The World Is Experiences Relevant Links: Facebook: https://www.facebook.com/Risewithnimbus/ Facebook: https://www.facebook.com/kevin.brenner.16 Instagram: https://www.instagram.com/investorkev/ Instagram: https://www.instagram.com/rise_withnimbus/ LinkedIn: https://www.linkedin.com/in/kevin-brenner-pmp-783471b6/ Website: https://www.risewithnimbus.com/ #podcast
Your metabolism is much more than just how fast you can lose or gain weight. The truth is, most of us don't understand how it works or the role it plays in our overall health. It's time to change that. Dr. Brenner made some fascinating discoveries involving NR, NAD+ and NAD. Along with other pioneers in his field, Dr. Brenner contributes to research making an everyday difference in peoples' lives. Tune into this fascinating episode on understanding human metabolism. || LINKS || https://www.cityofhope.org/faculty/charles-brenner | https://www.vivobarefoot.com/darienolien | Full Show Notes - https://darinolien.com/106-understanding-human-metabolism-dr-charles-brenner/