Podcasts about Chief scientific officer

Dr. Hoffman continues his conversation with Dr. Garth Nicolson, Founder, President, Chief Scientific Officer, and Emeritus Research Professor of Molecular Pathology at the Institute for Molecular Medicine in Huntington Beach, California, and Research Advisor for Nutritional Therapeutics.

Dr. Garth Nicolson, Founder, President, Chief Scientific Officer, and Emeritus Research Professor of Molecular Pathology at the Institute for Molecular Medicine in Huntington Beach, California, and Research Advisor for Nutritional Therapeutics, explains how membrane damage from free radicals and loss of mitochondrial transmembrane potential contribute to declining energy with age, noting studies in older adults showing improved energy output, fatigue, cognition, mood, and activity after NTFactor lipids, a protected phospholipid supplement balanced toward mitochondrial lipid composition. He describes evidence of lipid delivery using fluorescent-tagged lipids in sperm, with improved motility, and discusses applications including wound healing in veterans, removal of hydrophobic toxins via a concentration-driven “conveyor belt” process, and improved transport of nutrients like CoQ10. He details articles on normal aging, menopause-related changes supported by membranes, dementia risk linked to hearing loss, and rat studies showing delayed hearing loss with NTFactor, and mentions research on EMF sensitivity and planned schizophrenia trials.

We love to hear from our listeners. Send us a message.In episode 2 of this four-part in vivo-focused special series of Cell & Gene: The Podcast, Host Erin Harris sits down with Gopi Shanker, Ph.D., Chief Scientific Officer at Beam Therapeutics, for an in-depth conversation on the rapidly evolving landscape of in vivo gene editing and precision genetic medicines. Dr. Shanker discusses how next-generation base editing technologies are advancing beyond traditional CRISPR approaches by enabling precise single-base changes without creating double-stranded DNA breaks. They discuss the growing momentum behind in vivo delivery strategies, including targeted LNP technologies designed to reach tissues beyond the liver, as well as the operational and patient-centric advantages these approaches may offer compared to ex vivo therapies. Subscribe to the podcast!Apple  |  Spotify |  YouTubeVisit my website: Cell & GeneConnect with me on LinkedIn

We review the racing from the WTCS event in Alghero, IRONMAN Brazil and Challenge St Poelten. The Enhanced Games – what are the implications for clean sport and athlete integrity. Professor Alison Heather, Chief Scientific Officer at Insitugen, updates us on the evolution of anti-doping and the implications of new anti-doping and testing technologies. TIMESTAMPS 0:00:00 – Kate and Guy in Malaysia this week 0:01:07 – The Timber Trail 0:05:52 – WTCS Alghero race review 0:18:02 – IRONMAN Brazil 0:22:14 – Should IRONMAN standardise pay across all events 0:23:55 – Challenge St Poulton race review 0:25:45 – The Enhanced Games 0:34:22 – Testosterone clinics in NZ 0:36:13 – Professor Alison Heather intro 0:37:06 – Alison Heather on testosterone 0:40:00 – Jack Moody's testing 0:44:45 – Alison Heather on how far anti-doping has come 0:48:02 – How do we avoid contamination 0:58:22 – Alison Heather shares her thoughts on publicizing results LINKS: Jack Moody at https://www.instagram.com/jacktmoody/ Kate Bevilaqua at https://www.instagram.com/katebevilaqua/ Guy Crawford at https://www.instagram.com/guyrcrawford/ The Timber Trail at https://www.timbertrail.nz/ The Whaka 100 at https://www.whaka100.co.nz/ WTCS event Alghero at https://events.triathlon.org/2026-wtcs-alghero Challenge St Poelten at https://challenge-stpoelten.com/ IRONMAN Brazil at https://www.ironman.com/races/im-brazil The Enhanced Games at https://www.enhanced.com/ Professor Alison Heather at https://insitugen.com/about-us/

“Behind every breakthrough are countless failures no one ever sees—but that's exactly what makes progress possible.” Dr. Thomas Kaiser. When I have scientists on the podcast: they're some of the coolest, smartest, funniest people, and they're always willing (and excited) to explain what they do in ways you can actually understand. Dr. Tom Kaiser is no exception. He lives and works in Durham, North Carolina, and brings together an impressive mix of scientist, physician, and entrepreneur. His work focuses on designing better medicines using cutting-edge technology. He began his career at Emory University in Dennis Liotta's lab, working on antiviral drug discovery, and later helped pioneer early machine learning approaches in drug design. His research spans RSV, cancer, and neurodegenerative diseases, and he went on to earn his medical degree from the University of Oxford. Tom is now the co-founder and Chief Scientific Officer of Avicenna Biosciences, where he's leading the development of innovative therapies aimed at improving and saving lives. And my favorite detail from his bio? He ends it by mentioning the love of his life, his wife. I'll be honest, when I first met him, I told Dr. Kaiser he seemed like someone who must have been in a movie. He's just that cool. His Company: Dr. Thomas Kaiser shares the story behind his company's name, Ibn Sina, also known as Avicenna a true Renaissance figure of the Islamic Golden Age. A physician, philosopher, and scientist, Ibn Sina embodied the kind of multidisciplinary thinking that still drives innovation today. It's a powerful reminder that the roots of modern medicine, and the spirit of discovery stretch back centuries. The Part We Don't Talk About Enough Science is not a straight line. Not even close. Experiments fail. Clinical trials don't work. Hypotheses fall apart after years of effort. Funding can disappear. Progress can stall in ways that are frustrating and sometimes heartbreaking especially when patients are waiting. Dr. Kaiser speaks about this with a clarity and calm that really stayed with me. Because the truth is: scientists have to keep going anyway. They carry the weight of those disappointments and start again. They adjust, rethink, rebuild, and try again. Over and over. And that persistence? That's where breakthroughs come from. From the outside, it's easy to celebrate the wins ... the new drug, the successful trial, the headlines. But behind every one of those moments are countless failures no one ever sees. For families like ours, waiting, hoping, advocating it matters to understand that this difficult process is also what makes progress possible. Living the Dream What if you actually got to live the dream you had as a kid? In this conversation, Dr. Thomas Kaiser shares something surprisingly personal: he feels lucky to be doing exactly what he dreamed of as a child. That early curiosity grew into a career designing new medicines and pushing the boundaries of science. From imagination to impact, his journey is a reminder that sometimes those childhood passions really can shape the future. Go to Dr. Kaisers website:  https://www.avicenna-bio.com Like, subscribe, and comment on our podcasts!Please consider making a donation: https://thebonnellfoundation.org/donate/The Bonnell Foundation website:https://thebonnellfoundation.orgEmail us at: thebonnellfoundation@gmail.com Watch our podcasts on YouTube: https://www.youtube.com/@laurabonnell1136/featuredNew: Shop our merchandise! https://thebonnellfoundation.org/product-shop/Thanks to our sponsors:Vertex: https://www.vrtx.comViatris: https://www.viatris.com/enRead us on Substack: https://substack.com/@lstb?utm_campaign=profile&utm_medium=profile-pageWatch our trailer of Embracing Egypt: https://youtu.be/RYjlB25Cr9Y

Du schläfst ausreichend und fühlst dich trotzdem dauerhaft erschöpft? Woran liegt das? Wir gehen dem auf den Grund!In dieser Folge der Flowgrade Show spreche ich mit Dr. Wolfgang Brysch über die wahre Grundlage von Gesundheit, Leistungsfähigkeit und Langlebigkeit: biologische Energie.Wir tauchen tief in die Welt der Mitochondrien ein, sprechen über die größten Energieräuber unserer modernen Gesellschaft und darüber, warum immer mehr Menschen trotz optimierter Ernährung, Nahrungsergänzung und Schlaf das Gefühl haben, ständig „auf Reserve“ zu laufen.Dr. Brysch erklärt, warum Energie auf zellulärer Ebene entsteht, welche Rolle unser Gehirn dabei spielt und weshalb Faktoren wie künstliches Licht, Bewegungsmangel, Stress und Reizüberflutung unseren Energiestoffwechsel stärker beeinflussen als vielen bewusst ist.Außerdem sprechen wir darüber, warum die Qualität von Mikronährstoffen entscheidend ist, weshalb Bioverfügbarkeit oft wichtiger ist als die reine Dosierung und warum Gesundheit nicht durch einzelne Wundermittel entsteht, sondern durch das Zusammenspiel vieler Faktoren.In dieser Episode erfährst du:• warum so viele Menschen chronisch erschöpft sind• welche Rolle Mitochondrien für deine Energie spielen• warum das Gehirn zu den größten Energieverbrauchern gehört• die größten Energieräuber unseres modernen Lebens• weshalb künstliches Licht unseren Stoffwechsel beeinflusst• warum Bewegung ein zentraler Energielieferant ist• wie Mikronährstoffe tatsächlich wirken• weshalb Bioverfügbarkeit oft unterschätzt wird• was freie Radikale wirklich sind• wie du deine Energie nachhaltig verbessern kannstEine spannende Folge für alle, die ihre Gesundheit, Leistungsfähigkeit und Lebensqualität langfristig verbessern möchten.Viel Spaß beim ZuhörenGo for Flow

“What if the exhaustion, brain fog, low libido, and metabolic changes women experience in midlife are actually rooted in a deeper cellular energy crisis?” In this episode, Dr. Mariza sits down with Dr. Andrew Salzman — physician, inventor, biochemical engineer, and Chief Scientific Officer of Wonderfeel — to unpack the powerful connection between NAD, mitochondrial health, inflammation, ovarian aging, gut integrity, nitric oxide, and the dramatic energy shifts women experience during perimenopause and menopause. Dr. Salzman explains why menopause represents a major biological inflection point for women and how declining NAD levels may be contributing to fatigue, brain fog, poor recovery, metabolic dysfunction, sleep issues, reduced stress resilience, cardiovascular changes, and shifts in sexual health. Together, they explore the evolutionary role of menopause, why ovarian senescence accelerates aging pathways, how inflammation and the enzyme CD38 rapidly deplete NAD stores, and why the gut microbiome may be one of the biggest drivers of inflammation and energy decline in modern women. They also dive into nitric oxide production, cardiovascular health, the brain's dependence on NAD for sleep and cognitive function, and why ingredients like NMN and creatine are gaining attention for supporting healthy aging and resilience in midlife. If you've ever looked in the mirror and thought, “I don't feel like myself anymore,” this conversation will help connect the dots between your symptoms, your mitochondria, and your long-term vitality. ANDREW SALZMAN Dr. Andrew Salzman is a physician, inventor, biochemical engineer, and the Chief Scientific Officer of Wonderfeel. With more than 30 years of experience in drug discovery and development, over 170 scientific publications, and more than 50 patents, Dr. Salzman has spent decades studying aging biology, inflammation, cellular resilience, nitric oxide signaling, and mitochondrial health IN THIS EPISODE Why menopause is a major biological inflection point for women How declining NAD levels impact energy, metabolism, sleep, and brain function Why CD38 accelerates inflammation and NAD depletion during aging The surprising connection between gut health, inflammation, and menopause symptoms How estrogen decline contributes to leaky gut and systemic inflammation Why nitric oxide is essential for circulation, libido, cardiovascular health, and cognition The role of NAD in circadian rhythm, sleep quality, and stress resilience Why NMN and creatine are gaining attention for healthy aging and vitality QUOTES“Menopause will happen, but the question is: how do we maintain vibrancy and resilience through it?” “NAD is the common currency that drives energy throughout the body.” “The gut is the foundational driver of inflammation as we age.” “Without NADPH, you don't have nitric oxide production.” RESOURCES MENTIONED Subscribe and Save $15 on Wonderfeel Youngr™ NMN: https://tidd.ly/4rPnckS Use code ENERGIZED and get 30% off on your first BATCH order https://hellobatch.com/ENERGIZED Order my newest book: The Perimenopause Revolution https://peri-revolution.com/ Wonderfeel Website Wonderfeel Instagram Wonderfeel YouTube RELATED EPISODES  741: Estrogen, Gut Health, Mitochondria, and Cardiovascular Health: What Changes In Perimenopause with Dr. Siobhan Mitchel 691: The Fertility Crisis No One Talks About: Why Your Health Today Impacts Future Generations with Dr. Ann Shippy 717: “I Don't Feel Like Myself Anymore”: The Mental & Emotional Reality of Perimenopause 743: Why Your Heart Risk Changes in Menopause (And What You Can Do About It) with Dr. Jayne Morgan

Is it ok to store food in plastic containers?That's the question put by listener Joe Tattersall in this, the last episode in the current series of 'Sliced Bread'. Joe's noticed scuffs and abrasions on his reusable plastic containers and is concerned about whether that increases the risk of 'chemical leaching' into his food, or ingesting microplastics. He's keen to know if alternatives like glass, silicon, or metal containers could better for our health, as well as for the planet.And what about putting them in the microwave to heat food, using them to freeze food after batch-cooking, or putting them in the dishwasher to clean? To find out more, presenter Greg Foot is joined by Dr Stephanie Wright, Senior Lecturer in Environmental Toxicology at Imperial College London; and Jane Muncke, Managing Director and Chief Scientific Officer at the Food Packaging Forum.We're taking a break to prepare another batch of Sliced Bread but we're as hungry as ever for your suggestions of wonder products to investigate. Please do send your ideas to us either on email to sliced.bread@bbc.co.uk or to our WhatsApp number, 07543 306807.RESEARCHER: PHIL SANSOM PRODUCERS: SIMON HOBAN AND GREG FOOT

Day Break | Peace, War, and the Cost of Democrat Promises --- 00:00 - Monologue 19:05 – Grover Norquist, President of Americans for Tax Reform. Norquist discusses a proposed federal vehicle registration tax targeting electric vehicles and plug-in hybrids. He explains concerns that the plan could expand into a broader national vehicle tax while turning state DMVs into federal tax collection agencies. The conversation focuses on transportation costs, taxation, and government overreach affecting American drivers. 27:57 – Dr. Peter A. McCullough, MD, MPH, Chief Scientific Officer at The Wellness Company. Dr. McCullough discusses recent media attention surrounding Ebola and Hantavirus outbreaks. He explains the origins and transmission concerns tied to Ebola, screening procedures for incoming international flights, and questions surrounding long-term transmissibility of Hantavirus. He also shares preparedness recommendations for viewers concerned about emerging health threats. Visit twc.health/GRUBER and use promo code GRUBER to save. 38:09 - Monologue Featuring Ivey Gruber 57:17 – Scott Rasmussen, pollster, ESPN co-founder, and author of Out of Touch: The Elite One Percent and the Battle for America's Soul. Rasmussen discusses public distrust of political elites and polling data suggesting many Americans believe members of the political class would cheat to win elections or maintain power. 1:06:14 – Brian A. Rankin, Adjunct Fellow at the Competitive Enterprise Institute and telecommunications attorney. Rankin discusses the growth of wireless technology, the importance of unlicensed spectrum, and how innovations like Wi-Fi have transformed communications, business, and everyday life. 1:16:20 - Monologue 1:25:08 – Ron Rademacher, travel writer, author, speaker, and storyteller. Rademacher shares events happening around Michigan and highlights destinations, festivals, and outdoor activities taking place across the state. 1:35:14 – Dr. Matthew Mehan, educator and author of The American Book of Fables. Mehan discusses his new book and the importance of moral storytelling, civic education, and passing down foundational values through literature and fables. 1:44:06 – Ivey Gruber, President of the Michigan Talk Network. Gruber reflects on the beauty of America's national parks and the value of travel and exploration. The conversation highlights personal travel experiences and the importance of appreciating the country's natural wonders. --- Check out our brand new podcast, 'Forgotten America'... Episode 16 is live NOW at Steve Gruber on YouTube! Link below: https://youtu.be/I4UA2LzQQUg  

What does it really take to progress from bench science to leading a Biotech platform as Chief Scientific Officer? In this episode of Careers in Discovery, Daniel Tardiff, CSO at Camp4 Therapeutics, shares a candid look at building and scaling science inside an early‑stage biotech. From his foundations in RNA biology to advancing antisense programmes for haploinsufficiency-driven neurodevelopmental disorders, Dan unpacks how translational judgement is developed over time, not taught. Key takeaway: Career progression isn't about having perfect answers. It's about making credible decisions under uncertainty and bringing others with you as the science scales.

Brady Carter, Ph.D. is the Chief Scientific Officer at Carter Scientific Solutions. He specializes in water activity, moisture sorption, shelf-life stability, plant science, and wheat production and quality. He has 23 years of experience in research and development and previously was a Research Professor at Washington State University focusing on wheat end-use quality. Dr. Carter has pioneered work in using dynamic isotherms to investigate product stability and establish critical water activities for optimal shelf life. He also specializes in shelf-life loss and effective utilization of instrumentation to address product safety and quality issues. Dr. Carter holds a Ph.D. in Crop Science and Food Engineering and an M.S degree in Cereal Chemistry and Crop Science from Washington State University, as well as a B.A. degree in Botany from Weber State University. In this episode of Food Safety Matters, we speak with Dr. Carter [41:18] about: The basics of water activity, including how it is measured and how it differs from moisture content The influence of water activity on food safety and shelf life, and how water activity data can support the validation of shelf-life claims Ways manufacturers can incorporate water activity into their shelf-life and food safety testing, and during research and development when formulating products Regulatory expectations around water activity monitoring as part of validation and verification The realities of water activity measurement that make real-time, inline testing impractical with current technology How water activity monitoring can help mitigate food waste The importance of the statement, "water activity is the energy of water." News and Resources News Donald Prater Becomes New Head of FDA Human Foods Program [16:54]FDA Commissioner Steps Down, To Be Replaced by Agency's Human Foods LeaderTop U.S. Food Safety Officials Discuss Regulatory Landscape at Food Safety Summit FDA Encourages Industry to Develop Best Practices, Use Root Cause Analyses [20:30] FDA Finalizes Systematic Post-Market Food Chemical Review Process [21:34] FDA Launches One-Day Inspectional Assessments [22:30] Scientists Tackle Food Waste with More Accurate 'Sell By' Dates Based on Meat Microbial Activity [27:42] Monitoring Data Show EU Food Mostly Compliant with Pesticide Limits [35:58] Resources Food Safety Rockstar T-Shirts on Amazon (BE ADVISED: they run small) We Want to Hear from You! Please send us your questions and suggestions to podcast@food-safety.com

Marco Quarta is co-founder and Chief Scientific Officer of Rubedo Life Sciences, a precision-therapeutics company developing medicines that target the pathological cell states that drive age-associated disease. Marco's first appearance on the show was three years ago, in February 2023 (Episode 35), when Rubedo was a much earlier-stage company committed to the then-contrarian premise that "the senescent cell" is not a single entity but a heterogeneous family of cell states that needs to be deconvoluted at the single-cell level. In March 2026, Rubedo reported preliminary Phase 1b/2a clinical data for its lead candidate, RLS-1496, a first-in-class topical GPX4 modulator. Marco returns to the show to discuss what survived contact with human biology.In this episode, Chris and Marco unpack the readout from Rubedo's basket trial across four skin indications — psoriasis, atopic dermatitis, actinic keratosis, and photoaged skin — and the biology that underlies it. RLS-1496 came clean on safety in all four indications, with significant efficacy signals despite small patient numbers and short (20–30 day) treatment courses. More provocatively, the clinical and translational data have pushed Marco to redefine what kind of drug this actually is. Rather than a next-generation senolytic, GPX4 modulation appears to act as a state-gating intervention: it triggers ferroptosis in deeply senescent cells that have already crossed a redox threshold, while inducing a hormetic "redox reset" in stressed-but-recoverable cells that restores them to a healthier state. Marco proposes a new category to capture this dual action — adaptive senotherapeutics, or senoadaptive drugs — distinct from senolytics and senomorphics.The conversation traces the arc from Rubedo's founding thesis to a clinically validated platform (ALEMBIC, the AI-enabled single-cell multiomics engine that surfaced GPX4 as a target), through the strategic logic of leading with skin, into the broader question every longevity-biotech founder eventually has to answer: when does a disease-by-disease franchise become a credible preventive geroscience platform? Marco lays out the GLP-1 analogy explicitly — an anchor indication and a label-expansion roadmap that could carry GPX4 modulation from dermatology into respiratory, neurodegenerative, and metabolic disease, and ultimately into the use case where biomarkers of cellular senescence flag patients for therapy decades before disease becomes clinically apparent.The Finer Details:How Marco's 2023 contrarian view — that "senescent cells" hide a tissue- and state-specific reality — has been reinforced by the clinic, and how Rubedo's framing has shifted from "targeting senescent cells" to "targeting pathological cell states"The biology of GPX4 as a lipid-peroxidation gatekeeper, why senescent cells have intrinsic vulnerabilities (p16, p21, CDK4/6 inhibition) that make them ferroptosis-sensitive, and how Rubedo's approach differs from oncology-focused GPX4 programs at Takeda and othersThe "senoadaptive" mechanism — RLS-1496 eliminates GPX4-dependent senescent cells via ferroptosis while triggering NRF2/Keap1-driven redox reset, autophagy, and epigenetic remodeling in recoverable cells, restoring tissue trajectory from degenerative to regenerativeWhy Rubedo led with skin: clean regulatory path, accessible tissue, the ability to read out aging biology anddisease in the same trial, and a label-expansion runway into systemic indicationsPhase 1b (Europe) and Phase 2a (US) basket-trial results across psoriasis, atopic dermatitis, photoaged skin, and actinic keratosis: clean safety in 4/4 indications and significant efficacy signals — itch reduction in atopic dermatitis, decreased lesional thickness in psoriasis, target-engagement-correlated clinical improvement in photoaged skinThe richness of the translational dataset: biopsies, tape-stripping, spatial transcriptomics, proteomics, multiplex histomics, plasma biomarkers — all feeding back into ALEMBIC to refine the platformWhy actinic keratosis is the most strategically important indication — an age-related, chronic-inflammatory, precancerous condition where Rubedo can simultaneously test disease modification and biological-age reversalThe Rubedo–Beiersdorf partnership and the cosmetic vertical as a parallel commercial axisPipeline beyond skin: targeting aberrant basaloid stem cells in IPF and other pulmonary indications using different modalities (prodrugs, PROTACs, ADCs) to achieve cell-state selectivityThe longer-arc vision: senescence biomarkers as a "prediabetes-style" early signal, with senoadaptive drugs deployed decades before disease — and what a GLP-1-scale franchise might look like for GPX4 modulationQuotes:"There is not such a thing as a senescent cell — like there is not a cancer cell. And that was the initial idea. I'm glad that over time the field evolved. Now this is an accepted concept in the senotherapeutic space.""We are really talking about a dual function of RLS-1496 that can modulate the cell state depending on the adaptive response. That's why we call this — de facto — a new class of senotherapeutics. We call them adaptive senotherapeutics, or senoadaptive drugs — not a senolytic or a senomorphic, but working by modulating the cell state.""The best animal model for human therapies is human. As much as you can do preclinical work in animal models, it's always an approximation. We were able to test this directly in patients for safety, and in 4 out of 4 indications, we didn't have any safety signal.""Imagine you're taking care of a growing tree, and this tree has some dead leaves and some are a little bit stressed. If you shake the tree, the dead leaves will fall; the healthy leaves will not, because they're healthy and they resist the shake. But that shake actually gives the stressed leaves space and breathing room, and helps them to regain vitality. That's a little bit what GPX4 modulation does.""Senotherapeutics is a large, growing field — an untapped therapeutic opportunity. There is no such thing as a pan-senolytic or a pan-senotherapeutic, like there is no pan-oncotherapeutic. You need to understand the context. But these will all be part of the arsenal for true longevity medicine.""I don't see this as prevention of disease. The way I see therapies like ours, and the way the field of longevity is developing, is treating diseases decades before they develop. That's not a new concept — that's what we're doing in diabetes. You can be diagnosed with prediabetes today and reverse those biomarkers with lifestyle changes or metformin, and maybe never develop diabetes. That's exactly what we're doing here.""First of all, celebrating the first approved drugs from Rubedo — I don't think we're too far from that. But that's also a beginning, because you learn from the big momentum the GLP-1 agonists created: how a drug can start in one indication, create a new field, and prove that you can go beyond that. I hope in a few years we come back and talk about the next GLP-1 — this could be GPX4 modulators, or the senoadaptive drugs that are first in our pipeline."Links:Rubedo Life Sciences: https://www.rubedolife.comMarco Quarta's previous appearance on Translating Aging: Ep 35 — Targeting Pathologic Cells to Preserve Biological Youth

Kati Devaney is a neuroscientist and meditation teacher with over 25 years of practice. She earned her PhD in 2018 using fMRI to study attention and prediction updating in experienced Vipassana meditators and completed a postdoc at Harvard Medical School. She's now the Chief Scientific Officer at the Consciousness Foundation, co-founded the Berkeley Alembic and the SF Dharma Collective, advises Jhourney on the neuroscience of jhana, and has been quoted on the brain and meditation in The Atlantic, National Geographic, and TIME.In this episode we talk about weird stuff like cessation, jhanas, and non-duality. We also explore how the brain quietly constructs your sense of reality moment-to-moment, and how to (re)start a meditation practice. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit themetagame.substack.com

Episode SummaryIn this powerful episode of Breathless, we explore the boundary between physical restriction and newfound freedom. For decades, Cystic Fibrosis (CF) was a disease defined by limits: the limit of a breath, the limit of a career, and the limit of a lifespan.Today, those limits are being shattered. We follow two extraordinary journeys: Jeremy Vosburgh, a homicide detective who defied medical expectations to serve on the front lines of law enforcement, and Lauren Clift, a musical theater performer who transitioned from "choreographing her coughs" to taking her first full, effortless breath. This episode examines the "CF Without Limits" philosophy—a shift from merely surviving to actively planning for a future that was never guaranteed.Main Topics & Key Moments1. The Performer's MaskThe Hidden Struggle: Lauren Clift describes the grueling reality of performing in Legally Blonde while her lung function declined, forcing her to hide violent coughing fits behind stage choreography.The "Cough Blackout": A reflection on the magic of the stage and how, for years, the adrenaline of performance was the only thing that could temporarily silence the symptoms of CF.2. The Obstacle Course: Jeremy's StoryDefying the System: Jeremy Vosburgh shares how he bypassed the "rules" of CF to become a police officer, proving his capability through a high-intensity fitness test.Pepper Spray & Resilience: The incredible irony of a man with a respiratory disease voluntarily undergoing pepper spray training and physical altercations to protect his community.The 4 AM Discipline: A look at the brutal "old-school" grit required to balance nebs, neubulizers, and a demanding career before modern medicine arrived.3. Left Behind: The Rare Mutation GapThe Trikafta Blackout: While 90% of the CF community celebrated a miracle drug, Lauren was part of the 10% with rare mutations who were "left behind."Genetic Typos: CF Canada's Chief Scientific Officer, Paul Eckford, explains why certain genetic codes don't respond to standard treatments and the isolation that causes for patients.The Wall of Advocacy: How Lauren's mother—a pharmacist—had to beg politicians for the very drug she dispensed to others while watching her own daughter fade.4. "My Precious": The Turning PointThe Miracle Arrives: The bureaucratic and emotional hurdle of finally accessing Trikafta for rare mutations in July 2024.A Full Breath: Lauren describes the profound, tearful moment of rolling over in bed and taking a deep breath without coughing for the first time in years.5. The New FrontierPlanning to be an Old Man: Jeremy reflects on how his goals have shifted from "getting by" to the simple, once-impossible dream of growing old.Beyond the Lungs: CEO Kelly Grover discusses how CF Canada is pivoting to support "best lives"—focusing on fertility, education, and retirement planning.The Weight of the Future: Addressing the survivor's guilt and the mental health challenge of re-entering a world you thought you were leaving.Key Quotes"I would literally have to choreograph into my dance routine where I could cough without the audience hearing... otherwise I wouldn't make it through the show." — Lauren Clift"I don't like being told that it's impossible. I don't mind being told that it might be hard... but I would say that that's [nonsense] and that you can do it." — Jeremy Vosburgh"I dispense this drug to other CF patients that I see getting better. And I am watching my daughter die." — Lauren's Mother"Relief is the biggest thing... but also relief in just breathing. It's really cool to just breathe. I don't know if people know that." — Lauren Clift Hosted on Acast. See acast.com/privacy for more information.

Stephen Fagan, Business Development Manager, and Professor Vincent O'Flaherty, Chief Scientific Officer, GlasPort Bio, joined Cian Condon on the latest podcast version of the Signpost Series to discuss ‘GlasPort Bio: Reducing methane emissions from slurry'. A questions and answers session took place at the end of the webinar which was facilitated by Dr. Shaun Connolly, Teagasc Research Officer.  You can watch the webinar at:https://youtu.be/-evcIprvTT8?si=yHtDFraEIOdxagCh To register for future webinars go to:https://www.teagasc.ie/corporate-events/sustainable-agriculture-webinars/                        For more podcasts from the Signpost Series: https://www.teagasc.ie/signpostpodcast/ 

Dr. Fiona Lovely welcomes back Dr. Siobhan Mitchell, Chief Scientific Officer of MitoQ and an expert in nutritional neuroscience, for a conversation that digs deeper into the metabolic shifts women experience at midlife. Dr. Mitchell explains how declining estrogen directly impacts mitochondrial health, which in turn affects everything from energy levels and muscle strength to where the body stores fat. Listeners will learn why the same diet and exercise routines may stop working during perimenopause, and why that stubborn belly fat is not a personal failure but a biological response to changing hormones. Dr. Mitchell discusses the protective role of estrogen, the emerging understanding of the estrobolome, and practical options for support including HRT, phytoestrogens from sources like soy, and the lesser-known compound S-equol. She also shares what she wishes she had known earlier about stress and risk-taking, offering a personal insight that may resonate with many listeners navigating midlife changes.   Episode Highlights: How declining estrogen leads to reduced mitochondrial function, affecting energy, muscle strength, and inflammation throughout the body Why women gain visceral belly fat during perimenopause even when diet and exercise have not changed How the estrobolome, or gut bacteria responsible for recycling estrogen, can be supported to improve metabolic outcomes The role of phytoestrogens and S-equol, including why only about twenty percent of Western women can produce this beneficial compound naturally How HRT, phytoestrogens, and targeted supplements can work together or separately to support women through the menopausal transition This episode offers a clear roadmap for women who want to understand what is happening inside their bodies and take informed steps toward maintaining their health through the menopausal transition.    Thank you to our sponsors for this episode: The transition through midlife often brings a frustrating trio of shifts: the stubborn bloating, those unpredictable energy swings, and changes to the midsection that feel completely outside of your control. Harnessing the power of S-Equol, B. breve, and chromium, this formula is uniquely designed to support healthy estrogen signaling and metabolic function. It's about more than just numbers; it's about stabilizing blood sugar, restoring gut comfort, and supporting a healthy body composition so you can feel like yourself again. Go to www.mitoq.com and use code LOVELY10 for 10% off your first order! If night sweats and restless sleep are disrupting your rest, Cozy Earth's bamboo sheets and pajama sets are temperature-regulating and moisture-wicking — designed to sleep several degrees cooler than cotton. Because supporting your body through menopause starts with how you sleep. Visit cozyearth.com and use code LOVELY for 20% off.   Dr. Fiona Lovely is a longevity, health and wellness expert with specialties in menopause medicine, functional neurology and functional medicine.  She is speaking to the topics of women's health around perimenopause and menopause. How to work with Dr. Lovely: We get many requests for this info, so here it is!  First off, thank you for listening to the NYMM podcast.  It's because of your support, we can continue to dispense this information.❤️ Follow Dr. Lovely on IG and TikTok: @drfionalovely Follow the podcast on Facebook:  www.facebook.com/@notyourmothersmenopausepodcast Please sign up for our newsletter - Fiona's Friday Favourites!  This is where we make the first announcements, share course offerings, drop new episodes,  blog posts and the coveted 'Fiona's Favourites' column, etc.   drlovely.com You can also find some great resources there! Finally, a humble request:  If you love the podcast, please leave us a review!  It helps more people find useful info for a challenging time: https://podcasts.apple.com/ca/podcast/not-your-mothers-menopause-with-dr-fiona-lovely/id1097326296  Please scroll to the bottom of the page to leave a review.  Thank you! 

In this episode, I sit down with Dr. Luke R. Bucci, Chief Scientific Officer of Juvenon and a biomedical scientist, to reframe what healthy aging actually means. We break it down to two core pillars: circulation and metabolism. Because if your body can't efficiently deliver oxygen and nutrients, or convert them into usable energy, everything downstream is affected. We explore why blood flow is often overlooked, yet critical to cellular health, cognition, and recovery, and how metabolic function goes far beyond weight loss, influencing energy, repair, and overall performance. Dr. Bucci also challenges some of the current trends in longevity, including the hype around certain supplements, and emphasizes the importance of foundational physiology over quick fixes. We also touch on joint health, discussing compounds like glucosamine, chondroitin, and krill oil, and how they continue to play a role in long-term structural support. If you want to better understand what's really driving aging—and how to support it at a cellular level—this episode will shift your perspective.   Key takeaways: Glucosamine and chondroitin remain essential for joint health, working together to nourish cartilage and boost the body's natural repair processes. Circulation and nitric oxide production are key factors in aging, with Dr. Bucci noting a significant decline in these areas as early as age fifty. Dr. Bucci raises concerns over NAD supplements, suggesting they may have unrecognized cardiotoxic effects when consumed in high amounts. Proper metabolism is interdependent with good circulation, highlighting the importance of efficient energy conversion to reduce age-related symptoms. Dr. Bucci strongly advocates for foundational lifestyle habits such as exercise, targeted supplementation, and a balanced diet as cornerstones of healthy aging.   More About Dr. Luke Bucci: Dr. Luke R. Bucci, PhD, CNS-S, CCN (Ret.) is the Chief Scientific Officer of Juvenon and a biomedical scientist with more than 40 years of experience in nutrition, dietary supplements, and clinical laboratory science. He earned his PhD in Biomedical Sciences from the University of Texas Health Science Center at Houston and was among the first Certified Clinical Nutrition Specialists (CNS) and Certified Clinical Nutritionists (CCN), helping establish national competency standards in clinical nutrition certification. A respected authority in joint health, sports nutrition, women's health, probiotics, omega-3s, adaptogens, hormones, and regulatory science, Dr. Bucci has also authored scientific books and taught university-level courses on dietary supplement regulations. He is the recipient of the James Lind Scientific Achievement Award and the Supplement Industry Icon for Science & Innovation Award.   Website Instagram Connect with me! Website Instagram Facebook YouTube

You can stack every supplement, peptide, and biohack out there. It still won't fix the one thing wearing most of us down faster than any of it: unresolved stress and trauma.Dr. Bhargav Patel has spent his career studying how that wear and tear shows up in the brain, the body, and the lifespan, none of which a standard lab test will flag. He's one of the few doctors who treat the mind as part of the body rather than something separate from it.He walks us through the framework behind trauma recovery, why SSRIs work for reasons most people get wrong, and how processing trauma can hit 75% recovery rates. AI in healthcare comes up, too, along with why hallucinations are baked into every LLM and just how wide the mental health access gap is in the U.S."Supplements aren't the core of your longevity regimen. They're the last 5 to 10%. The 90% is the core health things we all know we should do: exercise, sleep, and eat well." ~ Dr. Bhargav PatelSupport the show and get 50% off MCT oil with free shipping—just leave us a review on iTunes and Spotify and let us know! https://podcasts.apple.com/us/podcast/live-beyond-the-norms/id1714886566Resources MentionedThe Body Keeps the Score by Bessel van der Kolk: https://www.penguinrandomhouse.com/books/313183/the-body-keeps-the-score-by-bessel-van-der-kolk-md/The Hypomanic Edge by John D. Gartner: https://www.simonandschuster.com/books/The-Hypomanic-Edge/John-D-Gartner/9780743243452MyPEAK Supplements: https://www.mypeaksupplements.com/ About Bhargav PatelDr. Bhargav Patel is a board-certified psychiatrist and NIMH-funded Child and Adolescent Psychiatry research fellow at Brown University. He's the founder of Sage Psychiatric Professionals and serves as Founding Medical Director and Director of AI Decision Support at Sully.ai. He's also the Co-Founder, CEO, and Chief Scientific Officer of MyPEAK. His upcoming book, Trauma Transformed, looks at how the brain actually heals from trauma, and what most of us get wrong about the process.Connect with Bhargav PatelWebsite: https://www.bhargavpatelmd.com/ LinkedIn: https://www.linkedin.com/in/bhargav-b-patel Newsletter: https://bhargavpatelmd.beehiiv.com/ Connect with Chris Burres Website: https://www.myvitalc.com/ Website: http://www.livebeyondthenorms.com/ Instagram: https://www.instagram.com/chrisburres/ TikTok: https://www.tiktok.com/@myvitalc LinkedIn: https://www.linkedin.com/in/chrisburresDisclaimerThe content shared in this podcast is intended for educational and informational purposes only. It does not constitute medical advice of any kind, nor does it include any specific claims or guarantees. The views expressed are based on personal experiences, research, and individual perspectives, and are meant to inspire and inform listeners on topics related to wellness, lifestyle, and personal development.

In this episode of Careers in Discovery, Adrian Gabriel Torres, Chief Scientific Officer at Aptadel Therapeutics, talks about developing RNA aptamer–based cancer therapies and leading scientific strategy in a preclinical biotech start-up. Adrian also shares his journey from academic research into industry, reflecting on the differences between academia and biotech, learning new skill sets, managing teams, and making career decisions along the way.

Algae is often overlooked, but it may be one of the most powerful tools for supporting energy, detoxification, and cellular health. In this episode, Dr. Jen sits down with Catharine Arnston, PhD, founder of ENERGYbits, to unpack the science behind spirulina and chlorella and why these ancient organisms are gaining attention in modern health. They explore how algae supports mitochondrial function, reduces oxidative stress through compounds like superoxide dismutase (SOD), and helps the body manage toxins and nutrient deficiencies. Catharine also explains the key differences between spirulina and chlorella, how each impacts the body, and how to incorporate algae into a daily routine for sustained energy, metabolic resilience, and long-term wellness.Catharine Arnston, PhD, is the Founder, CEO, and Chief Scientific Officer of ENERGYbits, a premium algae nutrition company. After a 25-year corporate career, she pivoted into health and wellness following her sister's breast cancer diagnosis, which led her to discover the powerful benefits of algae. Now a Board-Certified Health Coach with a PhD in Natural Health, Catharine has spent nearly two decades researching spirulina and chlorella and their impact on mitochondrial health, oxidative stress, and longevity. She is a leading voice in algae nutrition and a frequent guest on top health podcasts.Website: https://energybits.comInstagram: https://www.instagram.com/catharinearnstonLinkedIn: https://www.linkedin.com/in/catharinearnstonYouTube: https://www.youtube.com/energybitsThis episode is brought to you by Energy Bits. Visit www.energybits.com and use the code DRJEN to get 20% off your purchase.PODCAST: Thank you for listening please subscribe and share! Shop supplements: https://healthybydrjen.shop/CHECK OUT a list of my Favorite products here: https://www.healthybydrjen.com/drjenfavoritesFOLLOW ME:Instagram: https://www.instagram.com/integrativedrmom/Facebook:  https://www.facebook.com/integrativedrmomYouTube: https://www.youtube.com/@integrativedrmomFTC: Some links included in this description might be affiliate links. If you purchase a product through one of them, I will receive a commission (at no additional cost to you).  I truly appreciate your support of my channel. Thank you for watching! Video is not sponsored.DISCLAIMER: This podcast does not contain any medical or health related diagnosis or treatment advice. Content provided on this podcast is for informational purposes only.  For any medical or health related advice, please consult with a physician or other healthcare professionals. Further, information about specific products or treatments within this podcast are not to diagnose, treat, cure or prevent disease.

Join us in this episode as Tyler Korman, the Chief Scientific Officer and Co-Founder of eXoZymes, explains how their approach to AI-enhanced, cell-free enzyme technology is changing the way chemicals are produced… Hit play to discover: How enzymes are produced in large quantities. The ways that enzymes are used in everyday life.  The role that the microbiome plays in enzyme balance.  How sequencing data contributes to the creation of new compounds.  Tyler co-founded eXoZymes with Paul Opgenorth, building on research from the Jim Bowie Lab at UCLA. His expertise includes cell-free biomanufacturing, enzyme engineering, and AI-driven design. His work focuses on creating more efficient and sustainable methods for producing complex compounds by operating enzymes outside of living cells. To learn more about Tyler and his work, connect with him on LinkedIn!

On this episode Justin records live in Tampa FL at the Moffitt Cancer Center for this special series during CancerX 2026. His guests from the Moffitt Center are Xavier Avat, Moffitt Chief Business Officer and Dr. John Cleveland, Moffitt Center Director & Chief Scientific Officer. To stream our Station live 24/7 visit www.HealthcareNOWRadio.com or ask your Smart Device to “….Play Healthcare NOW Radio”. Find all of our network podcasts on your favorite podcast platforms and be sure to subscribe and like us. Learn more at www.healthcarenowradio.com/listen

Send us Fan MailToday we have Dr Rachael Brake on the show! Rachael is currently Chief Scientific Officer of Abdera Therapeutics, but has more than 20years in biopharma in a career that has gone from academia-to big pharma and more recently the biotech space.She's sharing how her experiences have helped form her leadership style which is centred on being open to vulnerability and always learning. For the early leaders trying to find your strengths and style, this episode is for you. Go to theleadcandidate.com for more info and the interview transcript 

She's 70 years old, holds a PhD she earned in her late 60s, and looks like she cracked the code on aging. But Dr. Catharine Arnston isn't selling a beauty secret she's sharing 17 years of research into two of the most scientifically documented superfoods on Earth: spirulina and chlorella.In this episode of SHE MD, Mary Alice Haney and Dr. Aliabadi sit down with Dr. Catharine Arnston, Chief Scientific Officer of ENERGYbits, for one of the most eye-opening conversations we've had on this show. It started with her sister's breast cancer diagnosis and a pivot away from a 25-year corporate career. What she found in the research changed everything she thought she knew about energy, brain health, aging, and women's bodies.This isn't wellness fluff. There are over 100,000 peer-reviewed studies on these two algae. NASA has been feeding them to astronauts for 50 years. The United Nations endorsed spirulina as the answer to world hunger. And yet most women in the Western world have never heard of them.Learn More Here: https://energybits.com/discount/SHEMD?rfsn=9096638.6abd9cc1&utm_source=refersion&utm_medium=affiliate&utm_campaign=9096638.6abd9cc1What You'll LearnWhy algae was the first life on Earth and why that matters for your bodyThe difference between macroalgae (seaweed, kelp) and microalgae (spirulina, chlorella)How spirulina creates cellular energy without the crash of caffeine or sugarWhat phycocyanin is and how this blue pigment behaves differently in healthy versus unhealthy cellsWhy mitochondria decline with age and how to protect them with nutritionThe role of superoxide dismutase (SOD) and why your body stops making it after age 30Why menopause damages women's mitochondria twice as fast as men'sHow chlorella detoxes heavy metals, glyphosate, aluminum, and other environmental toxinsWhy chlorella is essential for anyone on a GLP-1 or any weight loss journeyHow chlorella naturally supports serotonin, melatonin, sleep, and bowel motilityThe right dosage of each algae by age, condition, and time of dayWhy high heat in processing kills the benefits of most algae on the marketThe truth about excess stored iron, inflammation, and "rusting from the inside" after menopauseHow ENERGYbits are sourced in Taiwan in triple-filtered mountain spring waterHow to use algae for weight loss, sleep, brain fog, skin health, and longevityKey Timestamps00:00 Welcome Dr. Catharine Arnston & Why Algae Matters00:25 Catharine's Sister, Cancer, and the Origin of ENERGYbits01:49 Plant-Based Nutrition and the Otto Warburg Discovery02:46 Why People Don't Eat Vegetables (and What to Do About It)03:28 Why No One Knows About Algae Despite 100,000 Studies04:19 Why NASA Feeds Algae to Astronauts04:43 Algae Is Food, Not a Supplement06:45 "Aging Is Natural, Declining Is Not"07:08 Macroalgae vs. Microalgae Explained08:24 Why Lake & Ocean Algae Can Be Toxic09:27 Spirulina: Energy at the Cellular Level10:22 Why Algae Protein Beats Animal Protein10:49 Dosage 101: When and How Much to Take12:13 Phycocyanin: The Blue Pigment That Targets Unhealthy Cells14:34 The Electron Transport Chain & ATP (The "Ferrari" Analogy)15:48 Aging, Mitochondria & Cellular Decline16:13 Superoxide Dismutase (SOD): The Hidden Antioxidant17:53 Why Menopause Hits Women's Mitochondria Twice as Hard19:38 Brain Fog, Depression & Damaged Mitochondria20:37 Mary Alice's Family History & The Case for Prevention22:10 How Fast You'll Feel It & Mitochondrial DNA Regeneration23:16 Anti-Angiogenesis & Stopping Tumor Blood Supply24:10 Chlorella: The Body's Tow Truck for Toxins27:45 Chlorophyll, Hemoglobin & Building Your Blood28:35 Glutathione, Liver Health & Tryptophan29:03 Chlorella, Serotonin & Mood29:34 Chlorella for Bowel Motility30:25 The Athlete Protocol (NHL & NFL Dosing)31:12 Sleep, Melatonin & Why Chlorella Works at Night32:54 Chlorella for Chemotherapy Recovery36:01 Pricing, Daily Cost & the Discount Code36:45 Important: Talk to Your Oncologist Before Combining38:17 Algae for Weight Loss & GLP-1 Support40:32 Safety, Sourcing & Why ENERGYbits Are Grown in Taiwan42:20 Catharine's Trip to Taiwan & Why It Matters43:31 Excess Iron, Menopause & "Rusting From the Inside"46:07 Final Thoughts & Why Consistency Wins47:32 Absorption, Exosomes & Why Algae Works So Fast48:39 Dosage for Kids, Husbands & Pets49:41 Beauty Bits: The Pink Spirulina for Skin & Hair51:07 Mary Alice Starts Her Algae JourneyKey TakeawaysAging is natural, declining is notAlgae is food, not a supplement, so your body recognizes and absorbs it instantlySpirulina nourishes & energizes, chlorella detoxes & repairsYou need both algaes for different reasons, especially after 40Most brain issues trace back to damaged mitochondriaWomen lose antioxidant and hormone protection twice as fast as men in menopauseThe right dosage matters more than the right ingredientConsistency beats intensity, your body is not a light switchMost supplements are artificial, your body wastes up to 90% of themToxins live in your fat, so detoxing is part of any weight loss journeyThe science exists, the connection between scientists and women is what's missingMother Nature provided answers long before pharmaceutical companies didWhat you can't see at the cellular level is often what's hurting you mostGuest BioDr. Catharine Arnston is the founder and Chief Scientific Officer of ENERGYbits, the medical-grade algae company she launched 17 years ago after pivoting from a 25-year international corporate career to research plant-based nutrition for her sister, who had been diagnosed with breast cancer. Her research led her to spirulina and chlorella, two microalgae backed by more than 100,000 scientific studies, and to a mission of bringing clean, hand-sourced algae nutrition to women, families, and elite athletes around the world. Catharine earned her health coaching certificate from the Institute for Integrative Nutrition and went on to complete her PhD in her late 60s, becoming one of the most credentialed and outspoken advocates for algae nutrition in the world. Her upcoming book, Love Your Health to Bits with Algae, set for an October release, distills 17 years of research into accessible, "science with sarcasm" guidance for the everyday reader. Catharine lives by the philosophy that "aging is natural, declining is not" and is on a mission to make algae as common in the Western world as it has been in Asia for the past 60 years.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Investigative journalist and public health expert Emily Bass returns to A Shot In The Arm with the most consequential update on the global HIV response in months. Drawing on a brand-new report from Physicians for Human Rights and South African partners — built from 40 oral histories — Emily walks Ben Plumley through the human cost of the Trump administration's foreign aid disruptions, the staggering waste of dismantled prevention infrastructure, and the bizarre data spin emerging from the State Department. The episode also covers Dr. mike Reed's headline-making resignation as PEPFAR's Chief Scientific Officer, the dangerous quiet around supply chain contracts and bed-net procurement, and what the new “America First Global Health Strategy” is choosing to celebrate — and choosing to obscure. Ben closes with a preview of two new initiatives: AIDS 2060, a long-horizon project from A Shot In The Arm Media, and the rebrand of MTV Staying Alive Foundation to Shuga Global. 00:00 Welcome and Setup 01:18 Global Health Upheaval 03:13 PEPFAR Data Spin 04:07 South Africa Report 05:51 Prevention Platform Collapse 09:27 Clinic Breakdown Story 12:52 Why 18 Percent Matters 16:33 Community Resilience 19:22 Research Partnerships Lost 22:12 Treatment Disruptions 25:26 Trauma to Transition 31:11 Data Blackout Returns 39:07 Prep Data Mirage 42:08 Kids Treatment Declines 44:55 Age Data Removed 47:02 Congress Pushback 52:02 Supply Chain Breakdown 59:38 Last Mile Disaster Story 01:02:16 Orderly Transition Demands 01:06:23 AIDS 2060 Vision 01:10:35 Sugar Global Storytelling 01:15:20 Africa Led Future 01:20:42 Closing Thanks Read Emily Bass' Substack: https://substack.com/@emilysbass Check Out Ben's Substack: https://substack.com/@benplumley1 Join the Conversation! How do you see the future of global health unfolding? Share your thoughts in the comments! Subscribe & Stay Updated: Listen on Spotify, Apple Podcasts, or your favorite podcast platform. Watch on YouTube & subscribe for more in-depth global health.

In this episode of What is a Good Life?, Mark McCartney sits down with Dave Snowden - Founder and Chief Scientific Officer of The Cynefin Co., creator of the Cynefin Framework, and one of the most original thinkers working at the intersection of complexity science, organisational design, and human decision-making.The conversation moves through substrate theory, complexity science, psychological safety, the dangers of homogenisation, coherent heterogeneity, Celtic identity, indigenous rights, conflict resolution in Northern Ireland, and what a good life really comes down to.It is a beautiful mixture of thought provoking ideas and powerful lived experiences. For more from Dave Snowden:Website: https://thecynefin.co/LinkedIn: https://www.linkedin.com/in/dave-snowden-2a93b/For more from Mark McCartney:Newsletter: https://www.whatisagood.life/Website: https://www.mmcleadership.com/LinkedIn: https://www.linkedin.com/in/mark-mccartney-14b0161b4/YouTube: https://www.youtube.com/ ⁨@whatisagoodlife3875⁩  00:00  Substrate and What Emerges02:37  Fed Up With Management Fads05:54  When Ideas Come Together07:25  Celtic Presence and Attention10:20  The Reformation's Long Shadow13:28  The Problem With Safety16:38  Phase Shifts and Flipping21:17  Changing the Granularity24:48  Witnessing Violence29:12  Identity as Flow37:43  Metaphor as Intelligence51:57  What Is a Good Life?

Send us Fan MailA child develops normally, then something changes fast and families are left asking the hardest question: what happened? I'm joined by Dr. Brian Hooker, a PhD biochemical engineer and Chief Scientific Officer at Children's Health Defense, to walk through the claims he's studied for decades about autism regression, vaccine adverse events, and why he believes the modern childhood vaccine schedule creates risks that medicine has not honestly measured.We talk about what the schedule looks like in the first year of life, why early neurodevelopment may be uniquely vulnerable, and the biological pathways he points to, including oxidative stress, immune dysregulation, neuroinflammation, aluminum adjuvants, and blood-brain barrier permeability. We also discuss why some children may be more susceptible, including the role of reduced glutathione pathways and the high rates of mitochondrial dysfunction reported in subsets of autistic children.I also share why COVID made me question “safe and effective” talking points from institutions like the CDC and FDA, and how that re-opened questions about pediatric vaccine safety studies more broadly. We get into the controversy around placebo-controlled trials, the lack of research on vaccines tested in combination as a schedule, and the real-world pressure doctors face when they speak outside the mainstream. We close with additional environmental factors raised in the conversation, including glyphosate exposure and infant acetaminophen (Tylenol), plus what twin studies may suggest about genetics versus triggers.If you want deeper, more transparent research and better questions asked on behalf of kids and parents, listen now, then subscribe, share this with a friend, and leave a review so more people can find the conversation.https://www.amazon.com/Vax-Unvax-Childrens-Health-Defense-Kennedy/dp/1510766960Support the showhttps://www.jacksonfamilyministry.comhttps://bobslone.com/home/podcast-production/

In today's episode of Health Youniversity, Dr. Susan Fox sits down with Dr. Katie Worrilow — founder and Chief Scientific Officer of Life Air Systems, postdoctoral-trained reproductive physiologist, and former scientific director of IVF programs for over 20 years — for a conversation that will change how you think about your IVF cycle.Dr. Katie spent twenty years noticing something. That when construction began outside the hospital, when the medevac pad got repaved, when the parking lot was resurfaced — clinical pregnancy rates dropped. Not because of the medicine. Not because of the protocol. Because of the air surrounding the embryo during the most critical six to seven days of its existence outside the body. That realization became Life Air Systems — a patented air purification technology now installed in 41% of US IVF programs, awarded 23 patents, over 60 registered trademarks globally, and the 2025 Edison Award for innovation in healthcare.The data from clinical studies across several thousand patients showed a nearly 20 percentage point increase in clinical outcomes with complete air quality control. Across the full installation base worldwide, the average increase in clinical pregnancy rates is 14.9 percentage points — with corresponding improvements in implantation rates and blast conversion rates.You'll learn why the air surrounding a human embryo during culture matters.  Why the environment, and chemical pathogens like toluene from warm asphalt do to embryo development — and why you won't see the damage at day 3, only at day 5.   Blastocyst conversion rates and implantation rates are the metrics that tell the real story —   air quality has to do with both. And you'll learn what questions to ask your IVF clinic before your next retrieval or transfer about air quality at the transfer stage, why the same variable that improves outcomes also reduces the likelihood of needing multiple retrieval cycles — and what that means financially and emotionally. And you'll understand why Dr. Susan is calling out fertility insurance providers and employee benefits managers in this episode directly.This episode is for you if you're preparing for an IVF cycle and want to do everything possible to optimize your outcome, you've had a beautiful day 3 embryo report followed by a devastating day 5, you've been through one or more failed cycles and are trying to figure out what to do differently before the next one, you want

In this episode, Niall speaks with Dr. Christof Koch, Chief Scientist of the MindScope Program at the Allen Institute for Brain Science, former Professor at Caltech, and author of “Then I Am Myself the World”. Dr. Koch is a leading researcher in the science of consciousness and a key proponent of Integrated Information Theory. In this conversation, they explore: — Why consciousness may be fundamental, while physical matter exists only in relation to other things — How an experience on a beach in Brazil changed his understanding of reality — The discovery of “covert consciousness” in patients thought to be in vegetative states — How the perturbational complexity index (PCI) shows a clear boundary between conscious and unconscious states, and why this matters — How Integrated Information Theory approaches the question of free will You can learn more about Dr. Koch's work at https://christofkoch.com. --- Dr. Christof Koch is a Meritorious Investigator at the Allen Institute. Christof received his baccalaureate from the Lycée Descartes in Rabat, Morocco, his B.S. and M.S. in physics from the University of Tübingen in Germany and his Ph.D. from the Max-Planck Institute for biological Cybernetics in 1982. Subsequently, he spent four years as a postdoctoral fellow in the Artificial Intelligence Laboratory and the Brain and Cognitive Sciences Department at the Massachusetts Institute of Technology. From 1987 until 2013, Koch was a professor at the California Institute of Technology (Caltech) in Pasadena, from his initial appointment as Assistant Professor, Division of Biology and Division of Engineering and Applied Sciences in 1986, to his final position as Lois and Victor Troendle Professor of Cognitive & Behavioral Biology. See here for Christof's academic pedigree and his students. Christof joined the Allen Institute for Brain Science as Chief Scientific Officer in 2011 and became President in 2015. Christof writings and interests integrate theoretical, computational and experimental neuroscience with philosophy and contemporary trends, in particular artificial intelligence. His latest book, Then I Am Myself the World: What Consciousness Is and How to Expand It, publish in May 2024. His previous book, Consciousness: Confessions of a Romantic Reductionist, blends science and memoir to explore topics in discovering the roots of consciousness. Stemming in part from a long-standing collaboration with the late Nobel Laureate Francis Crick, Christof authored the book The Quest for Consciousness: A Neurobiological Approach. Koch also authored the technical books Biophysics of Computation: Information Processing in Single Neurons and Methods in Neuronal Modeling: From Ions to Networks, and served as editor for several books on neural modeling and information processing. --- Interview Links: — Dr. Koch's website: https://christofkoch.com — Dr. Koch's book: https://amzn.to/4mIKG9W

Tara Stoinski (A Gorilla Story) is a primatologist, conservationist, and CEO and Chief Scientific Officer of the Dian Fossey Gorilla Fund. Tara returns to the Armchair Expert to discuss growing up outside Philadelphia, her academic path from Tufts to Oxford to Georgia Tech, and balancing motherhood with a career studying gorillas in Rwanda. Tara and Dax talk about documenting rare gorilla dominance battles, the challenges of filming endangered animals in the wild, and how gorilla social structures differ from chimpanzees. Tara explains the importance of long-term behavioral research, how early life trauma can impact animal behavior, and why strong social bonds are key to survival in both gorillas and humans.Take printer ink off your to-do list with HP Smart Tank | hp.com/SmartTankCheck Allstate first for a quote that could save you hundreds: https://www.allstate.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Day Break | From Border Battles to Cancer Controversy—And Comey Indicted Again --- 00:00 - Monologue 18:50 – Sarah Starman, Senior Food & Agriculture Campaigner at Friends of the Earth. Starman discusses the “People v. Poison” protest, where cancer survivors are speaking out against the use of RoundUp. She explains the concerns surrounding the Supreme Court case and its broader implications for public health. 27:41 – Dr. Peter A. McCullough, Chief Scientific Officer at The Wellness Company. Dr. McCullough discusses recent findings on the use of ivermectin and mebendazole in cancer treatment. He explains how these anti-parasitic drugs may work, potential next steps in research, and considerations for those interested. Visit twc.health/GRUBER and use promo code GRUBER to save 10%. 37:27 - Monologue Featuring Ivey Gruber 46:25 – Hans A. von Spakovsky, Senior Legal Fellow at the Edwin Meese III Institute for the Rule of Law. Von Spakovsky discusses ongoing controversies at the U.S. Commission on Civil Rights. He also addresses concerns about election integrity and recent legislative developments. 56:26 – Laura C. Volpe, Founder of ManeInk HairLoss Solutions. Volpe discusses solutions for preventing hair loss and thinning using targeted treatments. Visit pureance.com and use code EARLY to save 35%. 1:15:19 - Monologue 1:24:03 – Ron Rademacher, travel writer, author, and Michigan backroads expert. Rademacher shares upcoming events and seasonal activities across Michigan. He also highlights mushroom hunting and the importance of doing it safely and knowledgeably. 1:34:11 – Mike Cox, former Michigan Attorney General and candidate for governor. Cox discusses calls for transparency regarding SPLC-related documents and outlines his path to winning the governor's race. He explains the key issues shaping his campaign. 1:43:07 – Ivey Gruber, President of the Michigan Talk Network. Gruber shares a story about middle school students stepping in during a bus emergency and other notable human-interest headlines. The segment also covers unusual trends and statistics making news. --- Check out our brand new podcast, 'Forgotten America'... The twelfth episode is live NOW at Steve Gruber on YouTube! Link below: https://youtu.be/1XbEJhJ6Wrk

“Why does your body stop responding… even when you're doing everything right?” In this episode, Dr. Mariza sits down with Siobhan Mitchell to unpack the true metabolic and cellular shifts happening in perimenopause and menopause. So many women feel like their body has suddenly turned against them—weight gain, fatigue, brain fog, and rising inflammation—despite doing all the right things. But this isn't a failure of effort. It's a biological inflection point driven by declining estrogen and its impact on metabolism, mitochondria, and vascular health. Together, they break down how estrogen loss reshapes everything from blood sugar control to fat storage, mitochondrial function, and long-term cardiovascular risk—while also exploring the emerging role of gut health and phytoestrogens like S-equol as targeted support. If you've been working harder than ever with fewer results, this episode will help you understand why—and what to do instead. Be sure to tune in! SIOBHAN MITCHEL Dr. Siobhan Mitchel, PhD, is a neuroscientist and Chief Scientific Officer at MitoQ. Her work focuses on mitochondrial health, cellular energy, and the role of oxidative stress in aging—particularly in women navigating perimenopause and menopause. She is passionate about advancing research that supports women's long-term health, metabolism, and resilience at the cellular level. IN THIS EPISODE Why your body stops responding the same way in perimenopause How estrogen loss impacts metabolism, fat storage, and blood sugar The role of mitochondria in energy, brain function, and weight changes Why visceral belly fat increases—and why it's more dangerous The connection between gut health, estrogen metabolism, and inflammation How phytoestrogens (like S-equol) support metabolism and hormone signaling Why midlife is a metabolic and vascular inflection point—not just hormonal QUOTES “This isn't a failure of effort—it's a biological shift happening beneath the surface.” “When estrogen declines, you don't just lose hormones—you lose metabolic protection.” “If you support your mitochondria, you support your energy, your metabolism, and your long-term health.” RESOURCES MENTIONED Order my new book: The Perimenopause Revolution HERE! https://peri-revolution.com/ Use code ENERGIZED and get 10% off MitoQ http://www.mitoq.com/energized MitoQ Instagram MitoQ Facebook MitoQ Youtube RELATED EPISODES  693: The Cellular Shift in Perimenopause: Mitochondria, Metabolism, and Energy 728: Why Brain Fog Isn't Random: The Hormone Shift Behind It 717: “I Don't Feel Like Myself Anymore”: The Mental & Emotional Reality of Perimenopause 705: The Metabolic Shift No One Warned You About in Midlife

The latest episode of the DDW 'In Conversation With' series is available to listen to below. This week, Bruno Quinney speaks to Angus Sinclair, Chief Scientific Officer at LabGenius Therapeutics. LabGenius is a biotech using AI and robotics to design new cancer therapies, and in vivo efficacy data reveals the company's novel T-cell engager shows complete tumour elimination in mice. Bruno talks to Angus about what T-cell engagers actually are, how AI is driving the company's approach, and why non-intuitive protein design is emerging within immuno-oncology drug development.   You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts.

Join our FREE upcoming masterclass: Why Midlife Weight Gain Won't Budge A smarter way to use GLP-1s in midlife without wrecking muscle or metabolism When: April 30th 11 am PST Register here: https://coaching.karenmartel.com/glp1-masterclass   There comes a point for so many women in their late 30s and 40s when they look in the mirror, or down at their belly, and think, what is happening to my body? You're still eating well. You're still exercising. You're still trying to do all the "right" things. And yet your body suddenly feels like it is playing by a completely different set of rules. In this episode, I sit down with Dr. Siobhan Mitchell, neuroscientist, nutritional scientist, and Chief Scientific Officer at MitoQ, to unpack what is really happening beneath the surface during perimenopause and menopause. We get into the fascinating science behind estrogen loss, shifting metabolism, belly fat, blood sugar changes, mitochondrial health, and why so many women feel like their bodies stop responding the way they used to. We also talk about phytoestrogens, the gut microbiome, and a little-known molecule called S-equol that may play an important role in metabolic and hormonal health during midlife. This is a smart, eye-opening conversation for any woman who wants to better understand why midlife weight gain happens, why timing matters when it comes to intervention, and what supportive tools may actually help.   In this episode, we cover: Why midlife weight gain often shows up around the belly How estrogen affects metabolism, appetite, blood sugar, and fat storage Why women become more prone to insulin resistance in perimenopause and menopause The role of mitochondria in energy, aging, and ovarian health Why belly fat in menopause is about more than just calories How stress and cortisol can amplify fat gain during midlife The difference between estrogen alpha and beta receptors What phytoestrogens are and how they may support women in menopause What S-equol is and why it may matter for metabolic health Why early support in perimenopause may be one of the smartest moves for long-term health   Who this episode is for This episode is for women in perimenopause or menopause who feel like their metabolism has changed overnight, their belly fat is increasing for no obvious reason, or their blood sugar and weight are becoming harder to manage despite doing all the right things. It is also for women who want a deeper understanding of estrogen, midlife metabolic changes, and supportive options beyond the usual tired advice to just eat less and move more.   Key Takeaways Estrogen is not just a reproductive hormone. It plays a major role in metabolism, fat distribution, blood sugar control, and muscle maintenance. Midlife belly fat is not just about overeating or aging. Hormonal changes during perimenopause and menopause directly influence where fat is stored and how energy is used. Insulin resistance, rising cholesterol, and metabolic dysfunction can begin during perimenopause, even before obvious menopause symptoms show up. S-equol may be a promising tool for supporting estrogen-beta activity, metabolic health, and symptom relief in midlife women. The earlier women understand and support these shifts, the better their chances of protecting long-term metabolic, cardiovascular, and brain health.     http://www.mitoq.com/karenmartel Coupon code: Martel10     Sponsors Head to https://cozyearth.com and use my code HORMONESBOGO to get 2 sets of sheets for the price of one. Do not miss this sale.     Are you in perimenopause or postmenopause and struggling with symptoms—but not getting the support you deserve? At Midlife Solutions, we specialize in hormone optimization for women in midlife. Our all-female clinical team offers telehealth care across all 50 U.S. states, with the ability to prescribe bioidentical estrogen, progesterone, testosterone, and thyroid medication.   Book your FREE Hormone Discovery Call Find out what's really driving your symptoms and what your next best steps are.   Visit the website: https://karenmartel.com   Shop the Midlife Solutions Store Over-the-counter bioidentical hormone creams and oils — no prescription needed. Including: • Progesterone • Estrogen Face Cream • Vaginal Moisturizer and more!   Take the Hormone Quiz Discover hidden hormone imbalances that could be driving your symptoms. Get personalized results (and yes, they may surprise you).   Women's Peptide Weight Loss Program Clinically guided, hormone-aware weight loss for midlife women.   Midlife RESET HRT Program A complete, supportive approach to hormone replacement therapy in midlife.   Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert   Karen's Facebook Karen's Instagram

Why do small-scale bioprocess experiments often fail to translate in scale-up despite “perfect” results on paper?Tibor Anderlei, Chief Scientific Officer and leader of customer support at Kühner Shaker, has spent three decades solving an issue that frustrates CMC leaders and biomanufacturing teams worldwide. He pioneered online monitoring in shake flasks, co-founded AC Biotec, and now helps organizations avoid costly trial-and-error with high-throughput screening and orbital shaken bioreactors.Topics discussed:Why orbital shaken bioreactors are fundamental to successful bioprocess development (03:11)The gap between educational practices and real-world bioreactor expertise (04:00)Tibor Anderlei's journey from the Technical University of Aachen to pioneering online monitoring technology in shake flasks (04:27)Reasons why published shake flask and microtiter plate experiments often fail to be reproduced in other labs (09:47)Key parameters frequently omitted from publications—including shaking diameter—and their impact on experiment reproducibility (13:10)Practical considerations for using microtiter plates and tubes, including automation compatibility and critical shaking speeds (14:13)Common scale-up failures due to oxygen limitation and mismatched aeration rates between small-scale and bioreactor systems (22:22)The effect of bioreactor geometry, such as neck shape, on process ventilation and performance (24:49)Smart insight: If scientists want scalable, reproducible success, the path starts with getting the details right—and keeping a sharp eye on both automation trends and the fundamentals of shaken cultures.Listen to the full episode with Tibor Anderlei to unpack the real “missing links” in bioprocess reproducibility and how to bridge small-scale insight to CMC scale-up.Building a robust scale-up strategy requires looking at the process from multiple angles—regulatory, digital, and operational. Listen to those previous episodes:Episode 03 - 04: How to Master Biotech Scale-up Without Guesswork with Leonardo SibilioEpisode 25-26: 9 Critical Steps for a Seamless Transition to Large-Scale ProductionEpisode 231-232: From IND to BLA: The Biologics CMC Decisions That Determine Regulatory Success with Henri KornmannEpisode 233-234: Why Most Bioprocess Automation Projects Fail with Anthony CatacchioEpisode 237-238: High-Throughput Microbial Screening with Sebastian BlumConnect with Tibor Anderlei:LinkedIn: www.linkedin.com/in/tibor-anderlei-66342411/Kühner Shaker website: www.kuhner.comShaking Technology Forum: www.shakingtechnology.comSupport the show

Welcome to Episode 303 of Autism Parenting Secrets. Today we're diving into an important and timely topic… aluminum exposure. My guest is Dr. Brian Hooker, a friend of the show and Chief Scientific Officer at Children's Health Defense. He's spent decades researching environmental factors that impact neurodevelopment and helping translate complex science into practical insight for parents. Aluminum isn't something most parents think much about… and when they do, they're often told it's not a concern. But there's more to understand. Because this isn't just about where aluminum shows up… It's about how it behaves once it enters the body, particularly in relation to inflammation and the brain. Brian shares what his latest research reveals, including why aluminum adjuvants stood out, how this form of aluminum is different, and why timing during early development matters. This is about clarity… so you can make more informed decisions for your child. The secret this week is… Take Aluminum Exposure Seriously You'll Discover: Why aluminum adjuvants stood out as the most concerning exposure in recent research (3:36) How aluminum nanoparticles can travel through the body and reach the brain (5:55) The biological mechanisms linking aluminum exposure to inflammation and brain impact (11:30) Why timing of exposure during early development is critical (27:32) Practical ways parents can think about reducing exposure and making informed decisions (30:14) About Our Guest: Dr. Brian Hooker is the Chief Scientific Officer at Children's Health Defense and a leading researcher on environmental factors impacting neurodevelopment. He has authored and co-authored numerous scientific papers examining vaccine safety, toxic exposures, and autism, and is widely known for his work translating complex science into actionable insights for parents. Contact: drbrianhooker@gmail.com References In This Episode: Aluminum Adjuvants, Autoimmunity, and Autism Spectrum Disorder: A Comprehensive Mechanistic, Neuropathological, and Legal Analysis Science Unleashed 2026 - May 9, 2026 Chandler AZ Additional Resources: To learn more about personalized 1:1 support go to www.elevatehowyounavigate.com If you enjoyed this episode, share it with your friends.

Dr. Anurag Singh, Chief Scientific Officer at Timeline Nutrition joins Modern Healthspan for an in-depth conversation about urolithin A and the science of mitophagy, the cellular process that cleans out damaged mitochondria.We explore the clinical evidence from multiple human trials: the ATLAS trial showing 12% muscle strength gains and 10% VO2 max improvements in sedentary middle-aged adults, independent studies in elite athletes demonstrating enhanced recovery and performance, and the groundbreaking MitoImmune trial published in Nature Aging revealing 20% increases in immune cell mitochondria in just 28 days.Dr. Singh provides practical guidance on dosing (500mg vs 1000mg), timing, and who benefits most from supplementation. We discuss why only 30% of people can produce urolithin A naturally from foods like pomegranates and berries, and how direct supplementation overcomes this limitation.Looking ahead, we cover Timeline's Healthspan XPrize semi-finalist status, ongoing blood-brain barrier research setting the stage for brain health trials, and Dr. Singh's vision for combining mitophagy activation with emerging therapies like mitochondrial transplantation. He also shares why he believes mitochondrial dysfunction is "the mother of all hallmarks of aging."Whether you're interested in the science of healthy aging, considering urolithin A supplementation, or want to understand the future of longevity medicine, this comprehensive conversation provides the evidence and insights you need.Topics covered:• What urolithin A is and how mitophagy works• ATLAS trial results: muscle, endurance, and inflammation• MitoImmune trial: immune system rejuvenation• Practical supplementation guide• Brain health research and future directions• The role of mitochondrial health in aging

Around 2018, I was living in Denver, Colorado and I was in my ongoing process of combining the fields of somatics, nutrition, nervous system, and trauma. I've wanted to learn as much as I can about all of the possible perspectives of what affects and shapes our food interactions. I was a member at the Denver Botanic Gardens and found out they were holding an all day nutrition workshop with Dr. Deanna Minich. I had been following her work for a long time and was so excited to learn from her in person. Some of the things I learned at that workshop I still cite today in sessions. I have admired the way Dr. Minich combines nutritional science and spirituality. So you can imagine how overjoyed I was when she agreed to come on the podcast and share her wisdom. In this week's episode, I chat with Dr. Deanna Minich, Nutrition Scientist and Chief Scientific Officer at Symphony Natural Health, about: Eating and circadian rhythmThe relationship between food and spiritualityFood and connection with lineage, ancestry, and generational traumaPersonal food stories and food associationsThe power of sensitivityEmbracing color, play, and creativity with food You can also read the transcript to this week's episode here: https://www.stephaniemara.com/blog/create-your-eating-timeline-to-understand-your-food-storyI hope you love this chat as much as I did and email me anytime with any insights you had from this episode! With Compassion and Empathy, Stephanie Mara FoxKeep in touch Dr. Deanna Minich: Website: https://www.deannaminich.com/ Facebook: https://www.facebook.com/deanna.minich/ Instagram: https://www.instagram.com/deannaminich/ YouTube: https://www.youtube.com/user/foodandspirit Linkedin: https://www.linkedin.com/in/deannaminich/Support the showKeep in touch with Stephanie Mara:Instagram: https://www.instagram.com/_stephaniemara/Facebook: https://www.facebook.com/stephaniemarafoxWebsite: https://www.stephaniemara.com/https://www.somaticeating.com/Linkedin: https://www.linkedin.com/in/stephmara/TikTok: https://www.tiktok.com/@stephaniemarafoxContact: support@stephaniemara.comSupport the show:Become a supporter: https://www.buzzsprout.com/809987/supportAll affiliate links: https://www.stephaniemara.com/resourcesReceive 15% off my fave protein powder with code STEPHANIEMARA at checkout here: https://www.equipfoods.com/STEPHANIEMARAUse my Amazon Affiliate link when shopping on Amazon: https://amzn.to/448IyPlSpecial thanks to Bendsound for the music in this episode. www.bensou...

In this episode of Resiliency Radio with Dr. Jill, Dr. Jill Carnahan explores the complex and rapidly evolving science behind Long COVID and autoimmune disease with Dr. Aristo Vojdani, a leading expert in immunology and functional medicine. Dr. Vojdani shares decades of groundbreaking research into how the immune system becomes dysregulated, revealing how infections, environmental toxins, and food antigens can trigger autoimmune reactions through mechanisms like molecular mimicry and gut permeability. The conversation dives deep into how SARS-CoV-2, Epstein-Barr Virus (EBV), and HHV6 contribute to Long COVID and neuroautoimmune conditions, as well as how early detection through advanced laboratory testing may help prevent disease progression. This episode offers powerful insights for both clinicians and patients seeking to understand the root causes of autoimmunity and chronic illness in the post-COVID era.

Your standard labs came back normal, but your cells might still be starving for energy. If you're doing everything right (the supplements, the diet, the sleep) but still can't shake the exhaustion, the problem might not show up on any bloodwork. What most providers never check is what's happening inside your cells: specifically how well your mitochondria are producing energy, and whether your circulation is quietly declining over time. In this episode, you'll learn: Why standard lab panels miss what's actually driving fatigue at the cellular level What mitochondria really do and how their decline leads to brain fog, weakness, and exhaustion The key supplements with real science behind them: CoQ10, L-carnitine, creatine, lipoic acid, and NAD The truth about nitric oxide: when it supports circulation and when it becomes a problem Why blood flow may be one of the most overlooked factors in chronic fatigue and long COVID recovery Guest: Dr. Luke Bucci is the Chief Scientific Officer of Juvenon, a clinical nutritionist, and a recognized leader in nutritional science with 37+ years in the dietary supplement industry working with Nobel Prize-winning scientists. He's also the recipient of the Science and Innovation Icon Award for his decades-long leadership and innovation in nutritional science and the dietary supplement industry. Discover your fatigue score and the root causes keeping you stuck: https://myfatiguescore.com Free Fatigue Masterclass: https://www.energymdmethod.com/masterclass See real client results: https://energymdmethod.com/results Chapters: 00:00 - Introduction 00:28 - Meet Luke Bucci, PhD 01:00 - Why Standard Labs Miss What's Happening Inside Your Cells 02:30 - What Mitochondria Actually Are 04:25 - What Happens When Mitochondria Don't Work Well 08:10 - Autophagy: How Your Body Takes Out the Trash 10:01 - Exercise, Isometrics and Mitochondrial Health 14:45 - Creatine: Not Just for Bodybuilders 17:10 - How Creatine Works in the Brain and Muscles 20:30 - CoQ10, L-Carnitine and Lipoic Acid for Energy 26:15 - Why Supplements Aren't Enough on Their Own 30:00 - Nitric Oxide, Blood Flow and Fatigue 34:10 - The Risks of Too Much Nitric Oxide 37:30 - Arginine Silicate and Polyphenols Explained 40:45 - Juvenon Products and Final Thoughts Connect with Dr. Luke Bucci: Juvenon Website: https://juvenon.com/ Subscribe to the EnergyMD Podcast for weekly conversations with leading experts on resolving ME/CFS and Long COVID by addressing the real root causes. . For more information about Evan and his program, Click Here.   Prefer to watch on Youtube? Click Here.   Please note that any information in this episode is for educational purposes only and does not constitute medical advice.

Vaccine policy, public health messaging, and medical freedom are rapidly shifting, leaving many parents and practitioners feeling uncertain about what to trust. In this episode, Dr. Jen sits down with Dr. Peter McCullough to unpack recent changes in vaccine policy, the role of federal and state-level decisions, and the growing conversation around informed consent and risk stratification. They discuss measles outbreaks, treatment approaches, and the importance of individualized care, while also exploring concerns around vaccine safety, scheduling, and long-term outcomes. This conversation offers a broader perspective on navigating health decisions in a complex and evolving medical landscape.Dr. Peter McCullough, MD, MPH, is an internist, cardiologist, and epidemiologist with over 1,000 scientific publications. He currently serves as Chief Scientific Officer for The Wellness Company and President of the McCullough Foundation. His work focuses on public health policy, informed consent, and advancing approaches to early treatment and patient-centered care. Dr. McCullough is a frequent speaker and advocate for medical freedom and individualized healthcare decisions.Website: https://petermcculloughmd.com Instagram: https://www.instagram.com/petermcculloughmd Facebook: https://www.facebook.com/Dr.Peter.McCulloughMD X: https://x.com/P_McCulloughMDYouTube: https://www.youtube.com/@petermcculloughmdLinkedIn: https://www.linkedin.com/in/petermcculloughmd PODCAST: Thank you for listening please subscribe and share! Shop supplements: https://healthybydrjen.shop/CHECK OUT a list of my Favorite products here: https://www.healthybydrjen.com/drjenfavoritesFOLLOW ME:Instagram: https://www.instagram.com/integrativedrmom/Facebook:  https://www.facebook.com/integrativedrmomYouTube: https://www.youtube.com/@integrativedrmomFTC: Some links included in this description might be affiliate links. If you purchase a product through one of them, I will receive a commission (at no additional cost to you).  I truly appreciate your support of my channel. Thank you for watching! Video is not sponsored.DISCLAIMER: This podcast does not contain any medical or health related diagnosis or treatment advice. Content provided on this podcast is for informational purposes only.  For any medical or health related advice, please consult with a physician or other healthcare professionals. Further, information about specific products or treatments within this podcast are not to diagnose, treat, cure or prevent disease.

In this episode of Data in Biotech, Ross Katz sits down with Robert Abel, Chief Scientific Officer of the Platform at Schrödinger, to explore how physics-based computational modeling is transforming drug discovery.  Robert unpacks why machine learning alone isn't enough to navigate the vast complexity of chemical space - an estimated at 10⁶⁰ possible drug-like molecules - and how integrating atomistic simulations with ML creates a more accurate, reliable, and scalable approach to identifying viable drug candidates. From free energy perturbation calculations to generative AI, Robert offers a rare inside look at how Schrödinger's technology platform is accelerating the path from target identification to clinical candidate and where the field is headed next. What you'll learn in this episode:  >> Why chemical space (~10⁶⁰ molecules) makes purely data-driven ML approaches fundamentally insufficient for drug discovery, and how physics-based sampling solves the training data problem >> How free energy perturbation (FEP) calculations enable quantitative prediction of protein-ligand binding affinities at near-experimental accuracy (~1.2 kcal/mol RMSE) >> How Schrödinger's active learning framework combines physics-based simulations and ML to triage billions of candidate molecules before committing to wet lab synthesis >> Why Schrödinger operates across three business lines; software licensing, collaborative programs, and proprietary drug discovery and how each strengthens the underlying technology platform >> Where the next frontiers lie: routine anti-target selectivity profiling, retrosynthetic AI integration, and the expanding role of generative ML in de novo molecular design Meet our guest: Robert Abel is Chief Scientific Officer, Platform at Schrödinger, where he helps lead the scientific direction behind computational approaches that support modern drug discovery and molecular design. With a PhD in Chemical Physics from Columbia University and a deep background in computational chemistry, he has held multiple senior science leadership roles at Schrödinger, guiding teams that build and scale scientific methods into production-grade platforms used across research and industry. Connect with Robert Abel on LinkedIn  About the host: Ross Katz is Principal and Data Science Lead at CorrDyn. Ross specializes in building intelligent data systems that empower biotech and healthcare organizations to extract insights and drive innovation. Connect with Ross Katz on LinkedIn Connect with us: Follow the podcast for more insightful discussions on the latest in biotech and data science.Subscribe and leave a review if you enjoyed this episode! Sponsored by… This episode is brought to you by CorrDyn, the leader in data-driven solutions for biotech and healthcare. Discover how CorrDyn is helping organizations turn data into breakthroughs at CorrDyn.

Dr Eduardo (Eddy/Eddie) Perez, PhD is the Chief Scientific Officer at Signum Biosciences and a scientific lead behind Epicutis®. He earned his PhD in Biochemistry and Molecular Biology from Rutgers University, with research focused on signal transduction. Dr Perez has more than a decade of experience across biotech and R&D, with expertise spanning dermatology-focused scientific development, evaluation of novel compounds, and formulation science for skin-focused applications. In this episode of Doctor Diaries, live from Melbourne's ASCPD Conference, Dr Eddy Perez joins Hanya Oversby to unpack the science lens behind modern skincare innovation — from how skin barrier biology shapes real-world routines, to why formulation choices matter just as much as headlineingredients. We'll explore how scientific teams assess new compounds, what “skin resilience” means in practical terms, and what clinicians should listen for when separating meaningful innovation from marketing noise. For more information on Dr Perez, click herehttps://www.linkedin.com/in/eduardo-perez-9b5a947/ More information about Hanya Oversby can be found onhttps://hanyaoversby.com.au/ #dreduardoperez #eddieperez #epicutis #signumbiosciences #ascpd.org.au#medicalworld #doctordiariespodcast #hanyaoversby #podcast #medicalbusiness #doctorsofinstagram#aestheticworld #doctor #secretsource #medicalpodcast Doctor Diaries is a podcast series designed for healthcare professionals, featuring in-depth interviews with experienced clinicians across medical aesthetics, dermatology, surgery, and integrative medicine. Each episode provides insights into clinical approaches, practice development, and the realities of patient care in today'sregulatory landscape.This content is intended for qualified healthcare professionals only and may discuss prescription-only products, regulated procedures, and clinical experiences not suitable forgeneral public promotion. Always refer to relevant professional guidelines and product information.

Dr. Lynn Hellerstein of Vision Beyond Sight sits down with Dr. Amy Laster, neuroscientist & Chief Scientific Officer at the Foundation Fighting Blindness that advances cures for retinal diseases, to talk about bridging cutting-edge science with human connection and leading the Foundation Fighting Blindness to accelerate research for rare eye diseases. As a neuroscientist-turned-nonprofit leader, she shares how translating complex science into human impact is advancing treatments – while keeping patients, families, and possibility at the heart of every breakthrough. Dr. Laster shares her journey from neuroscience into nonprofit leadership, revealing how her “superpower” of big-picture strategic thinking helps drive research forward more efficiently. Together, they unpack what retinal diseases are, the scope of their impact—from rare inherited conditions to age-related macular degeneration—and the innovative therapies offering new hope. From gene augmentation treatments like Luxturna to emerging clinical trials in retinal cell transplantation, this conversation bridges complex science with real-world impact. You'll also hear powerful patient stories, including Rebecca Alexander's experience with Usher syndrome and Lindsey Rambo's groundbreaking role in early gene therapy trials. Beyond the lab, Dr. Laster highlights the importance of community, family support, and ensuring patients remain at the heart of every scientific advance. She also discusses the Foundation's ambitious 5-year strategic plan and the evolving ways they measure success—including new technologies like virtual reality testing and using focal points of light. This episode is a compelling look at how innovation, empathy, and purpose are shaping the future of vision science—and why no one facing vision loss has to navigate it alone. Dr. Lynn Hellerstein, Developmental Optometrist, co-owner of Hellerstein & Brenner Vision Center, P.C., award-winning author and international speaker, holds powerful and inspiring conversations with her guests in the areas of health, wellness, education, sports and psychology. They share their inspirational stories of healing and transformation through their vision expansion. Vision Beyond Sight Podcast will help you see with clarity, gain courage and confidence. Welcome to Vision Beyond Sight! Also available on Apple Podcasts, iTunes, Google Podcasts, Spotify, iHeart Radio, Audible and Stitcher.

Dr. Luke Bucci joined Jerry for a conversational podcast discussion about health and nutrition, particularly focusing on aging after 40. The conversation covered specific supplement recommendations from Juvenon, particularly their BloodFlow 7 product focused on nitric oxide production, and Dr. Bucci shared insights about nutritional testing and the importance of understanding individual health needs through proper testing rather than relying solely on conventional medical approaches. Key takeaways After age 40, the body undergoes significant changes, but maintaining a healthy, functional body is achievable through proper nutrition, exercise, and supplementation The three most important supplements for everyone are vitamin D3, magnesium, and omega-3s Exercise, particularly strength training, is essential for preventing muscle loss and maintaining functionality as we age Diet should focus on whole, fresh foods prepared at home rather than processed or restaurant foods Blood flow and nitric oxide production decline significantly with age, dropping 20% by age 40 in healthy individuals and 60% in unhealthy individuals Nutritional changes and supplementation require 3-4 months to show meaningful results, not just weeks Krill oil may be superior to fish oil for omega-3 supplementation due to better absorption and reduced oxidation Dr. Luke Bucci is the Chief Scientific Officer of Juvenon, a clinical nutritionist, and a recognized leader in nutritional science with 37+ years in the dietary supplement industry working with Nobel Prize-winning scientists.   Visit ConfidenceThroughHealth.com to find discounts to some of our favorite products.Follow me via All In Health and Wellness on Facebook or Instagram.Find my books on Amazon: No More Sugar Coating: Finding Your Happiness in a Crowded World and Confidence Through Health: Live the Healthy Lifestyle God DesignedProduction credit: Social Media Cowboys

The Steve Gruber Show | Chaos, Conflict, and Control: The Forces Shaping America Right Now --- 00:00 - Monologue 18:54 – Doron Kempel, former commander of the IDF's elite Sayeret Matkal special operations unit. Kempel reacts to the resignation of Counterterror Chief Joe Kent amid disputes over the Iran threat. He explains what this signals about internal disagreements and the broader security implications. 27:49 – Dr. Peter A. McCullough, MD, MPH, Chief Scientific Officer at The Wellness Company. Dr. McCullough discusses ongoing debates over mRNA vaccines and concerns from medical freedom advocates. He also addresses long-term health questions, potential biothreat risks tied to global conflict, and preparedness strategies, including access to prescription medications. Visit twc.health/GRUBER and use promo code GRUBER to save 10%. 37:57 - Monologue 46:50 – Stephen Moore, founder of the Ukraine Freedom Project. Moore discusses concerns about China's influence and what he describes as ongoing geopolitical conflict involving both China and Russia. He also questions U.S. political responses to foreign threats and military actions impacting Americans. 56:55 – Kris Ullman, President of Eagle Forum. Ullman discusses detransitioners speaking out as Congress considers the Chloe Cole Act. She explains the policy debate and the personal stories influencing lawmakers. 1:15:41 - Monologue 1:24:36 – Ron Rademacher, travel writer, author, speaker, storyteller, and record-holder for getting lost on Michigan's back roads. Rademacher highlights events and destinations happening around Michigan. He shares ideas for exploring local communities and seasonal attractions. 1:34:39 – Rep. Michael Echols, representing Louisiana's 14th District and Chairman of the House Republican Delegation. Echols discusses how President Trump's tough-on-crime policies are playing out in Louisiana, particularly in New Orleans. He explains what state leaders are seeing on the ground. 1:43:18 – Rep. Byron Donalds, representing Florida's 19th Congressional District. Donalds discusses the importance of the SAVE Act and voter ID requirements, along with his perspective on current political debates. He also touches on developments in Iran and his campaign for governor of Florida. --- Check out our brand new podcast, 'Forgotten America'... The fifth episode is live NOW at Steve Gruber on YouTube! Link below: https://youtu.be/CruHHRXxRE4

DR1In our 'Asshole is selfish' headline of the week. Billionaire Uber co-founder Travis Kalanick admits strategically moving to Texas before California wealth tax***************Kalanick was caught on camera in a heated argument with an Uber driver, who complained about falling fares and the company's treatment of drivers: "Some people don't like to take responsibility for their own sh*t"In our 'Top snarky podcast hosts plead with airline companies to stop the share buyback bullshit and pay airport workers. ‘Once again, air travel CEOs are bullshit artists'' headline of the week. Top airline CEOs plead with Congress to restore DHS funding and pay airport workers. ‘Once again, air travel is the political football'***************Between June 1, 2025, and March 16, 2026:Southwest repurchased $2.6B in 2005; $400M in 2026United $1.5B5 NEOs: $91 million in 2025Scott Kirby $34M; $97M in shares Delta focused on $4.8B debt reductionFrontline Transportation Security Officers (TSOs, Airport Screeners): 50,000$328M per monthIn our 'Pervy owner does pervy stuff and everybody is fake shocked.' headline of the week. It Was Going to Be Magic City Night at the Atlanta Hawks. Then the Outrage Poured In.***************Tony Ressler founded the private equity firm Apollo Global Management with Leon Black.An independent review revealed that Leon Black paid Jeffrey Epstein $158M for financial and tax-planning services between 2012 and 2017. These payments occurred after Epstein's 2008 conviction for soliciting an underage girl.Ressler is the brother-in-law of Leon Black (Black is married to Ressler's sister, Debra) In our 'College dropout techbro ignores actual experts, part 17 million ' headline of the week. OpenAI's own mental health experts unanimously opposed “naughty” ChatGPT launch*************** The probably might be too many women and not enough Stanford? The council consists of the following eight independent experts:David Bickham, Ph.D. – Research Director at the Digital Wellness Lab at Boston Children's Hospital and Assistant Professor at Harvard Medical SchoolMathilde Cerioli, Ph.D. – Chief Scientific Officer at everyone.AI and researcher in cognitive neuroscience and psychologyMunmun De Choudhury, Ph.D. – Professor of Interactive Computing at Georgia Tech, specializing in how technology shapes mental healthTracy Dennis-Tiwary, Ph.D. – Professor of Psychology at Hunter College and co-founder/CSO of Arcade TherapeuticsSara Johansen, M.D. – Clinical Assistant Professor at Stanford University and founder of Stanford's Digital Mental Health ClinicDavid Mohr, Ph.D. – Professor at Northwestern University and Director of the Center for Behavioral Intervention TechnologiesAndrew K. Przybylski, Ph.D. – Professor of Human Behavior and Technology at the University of OxfordRobert K. Ross, M.D. – Former President and CEO of The California Endowment and a national leader in public health.In addition to the council's pushback, Ryan Beiermeister, OpenAI's head of product policy, was reportedly fired in January 2026 after being an outspoken internal critic of the erotica rollout. OpenAI has denied her dismissal was related to her opposition, citing separate workplace allegations that Beiermeister has called "absolutely false."In our 'Petulant manchild with no regulatory or societal guardrails screws up again and bails himself out with shareholder money from a different company' headline of the week. Elon Musk admits xAI ‘wasn't built right' as only 2 co-founders remain and its biggest AI bet stalls out***************The people leaving xAI right now aren't "legacy" employees—they are the hand-picked superstars Musk himself recruited in 2023 to build his AI dream.Out of the 12 original co-founders, 10 are gone. This isn't just "trimming the fat"; it's the original architects of the company walking out the door.In early 2026, Tesla (a public company) invested $2B into xAI.Tesla shareholders are furious, arguing that Musk used their money to fund a "broken" startup, then tucked it away inside his private SpaceX empire where there is less public oversight.Total Headcount Before Buyout: Approximately 7,500 to 8,000 employees.In his first week, Musk fired roughly 50% of the staff (about 3,700 people) overnight.Shortly after, he issued his famous "extremely hardcore" memo. When hundreds of employees refused to sign it and resigned instead, the headcount plummeted further.By April 2023, Musk confirmed in a BBC interview that the workforce had been slashed by 80%, leaving only about 1,500 employees. MM1In our 'The world's most stable billionaire announces a billionaire to all other billionaires ratio of 693:1' headline of the week. Elon Musk Is Now Worth More Than Bottom 693 Billionaires CombinedIn our 'In news celebrated worldwide, older women announce a "please save us from tech bros" to asshole ratio of 64:1 Elon Musk' headline of the week. Older women set to inherit most of $54 trillion in ‘great wealth transfer' to widowed spousesIn our 'Asshole wants you to know he is still here' headline of the week. ‘I never left': Travis Kalanick launches new robotics company Atoms with manifesto"At Atoms we make gainfully employed robots — specialized robots with productive jobs that bring abundance to their owners and society at large,"In our 'Company founder announces major "stealth mode" company perk is stealthy sexual harassment' headline of the week. Travis Kalanick sees benefits of being in stealth mode for 8 years. ‘You build a culture of people that want to build and do not need to be famous'In our 'Christmas, St. Patrick, Mel Gibson, and Casper the Friendly Ghost have reportedly filed complaints with the EEOC' headline of the week. Nike and Coca-Cola cases point to the next DEI fight: who gets to claim discriminationDR2In our 'Sheryl Sandberg says "If I could have worked at Facebook things would have turned out differently."' headline of the week. Sheryl Sandberg says Silicon Valley's hypermasculine rhetoric is ‘terrible'—contributing to ‘one of the worst' corporate climates she's ever seen*************** In our 'Explosive Messages Show Live Nation Thinks Customers Are ‘Stupid'; board member Richard Grenell Demands Credit for Same Observation' headline of the week. Live Nation Directors Mocked Customers in Explosive Just-Released Messages, Saying They're “Stupid” for Allowing Themselves to Be Gouged***************"Yes, I cut the DEI bullshit." — In a leaked 2025 email Grenell justified dismantling diversity programs by labeling them "woke" initiatives that "haven't made money."appointed to the Live Nation board on May 19, 2025, but was not up for the vote at the AGM on June 12, 2025In our 'Gun manufacturers say, "Oh no, it's not the gun that kills people, it's the pesky bullets."' headline of the week. She spent 16 hours on Instagram in a day. It's up to a jury to decide if Meta is to blame*************** In our 'She responded to "O" with "K," she said "J' to "D," and she responded to "F" with a simple "U"' headline of the week. Mary Barra still responds to ‘every single letter' she gets by hand despite running $65 billion automaker General Motors***************She did not say "V" to "E"In our 'OpenAI Chairman Admits It's Painful Watching AI Replace His Coding, Less So Watching It Accelerate the Collapse of Global Democracy' headline of the week. OpenAI Chairman says it's 'hard, emotionally' to let AI write his code: 'I have a hard time not caring'*************** MM2In our 'Proposals include a reduction in the CEO pay ratio from 1800:1 to 1799:1, for my boss to stop calling me Carl when my name is Todd, having a job, and not to have to take out my nose ring I got in 1998' headline of the week. Starbucks union sent the company a proposed contract. Here's what baristas wantProtections for union baristas against discrimination, unjust firings and temporary or permanent store closures.Starting wage floor of $17 per hour, down from its prior proposal of $20 an hour but still above the company's current starting wage of $15.25 to $16 an hour in 43 states.Annual raises of 4%.A process for baristas, management and union representatives to resolve workforce grievances.A dress code endorsed by the union.Requirement for at least three workers on the floor at all times and enforceable staffing and safety protections.A mandate to offer open hours to existing employees before hiring new baristas.Resolution of hundreds of outstanding unfair labor practice charges.In our 'But Sam Altman is SORRY' headline of the week. Professors Say AI Is Destroying Their Students' Ability to ThinkIn our 'Don't be fooled, I'm actually a MAN' headline of the week. CoStar Group Appoints Nana Banerjee to Its Board of DirectorsI pulled every Trade Wire story with a director appointment - 69 in the last week, all press released, some private some public - and here's the count: 60 men added to boards, 9 women added, 1 woman leftIn our 'Building on Warren Buffet's innovative "Giving Pledge", billionaire creates the rival "Taking Pledge"' headline of the week. Peter Thiel is actively convincing billionaires to abandon The Giving Pledge — and it's workingIn our 'When asked for comment, ISS asked if Nelson Peltz was involved.' headline of the week. The Coca-Cola Company Announces Maria Elena Lagomasino Will Conclude Her Service on the Board of Directors

Air quality is an often-overlooked factor that can significantly impact patient outcomes. In this episode of the Healthcare Success Podcast, Stewart Gandolf speaks with Katy Worrilow, Founder and Chief Scientific Officer of LifeAire Systems, about how unexplained fluctuations in IVF pregnancy rates led to the discovery that airborne contaminants were affecting embryo viability. Katy explains how this insight led to the development of a technology designed to destroy airborne pathogens rather than simply capture them—an innovation now being used in IVF labs, operating rooms, NICUs, senior living communities, and other healthcare environments.

Guest: Martin Brenner, Ph.D., Chief Executive Officer and Chief Scientific Officer at iBioCompany: iBio, Inc. (NASDAQ:IBIO)Website: https://ibioinc.com/Martin's Bio:Dr. Brenner has a strong history of success heading drug discovery and development teams at several of the world's leading pharmaceutical companies, including AstraZeneca, Eli Lilly and Company, Pfizer Inc., and Merck Research Laboratories. Most recently, Dr. Brenner served as the CSO at Pfenex Inc., which, using its patented Pfēnex Expression Technology® platform, created an advanced pipeline of therapeutic equivalents, vaccines, biologics and biosimilars. Pfenex was acquired by Ligand Pharmaceuticals Incorporated for approximately $516 million in October 2020. Previously, Dr. Brenner served as the CSO at Recursion Pharmaceuticals, Inc., a company focused on accelerating drug discovery for rare diseases and diseases with high unmet medical need. Prior to his time at Recursion, he was Vice President and Head of Research & Early Development at Stoke Therapeutics, Inc., a biotechnology company using antisense oligonucleotides to increase gene expression for the treatment of rare diseases. Prior to Stoke, he was Executive Director at Merck, where he built a biotech unit from scratch, focusing his team's research on diabetes and nonalcoholic steatohepatitis (NASH). Earlier in his career, Dr. Brenner was the Senior Director and Head of cardiovascular, renal, and metabolism (CVRM) biosciences at AstraZeneca. In addition, Dr. Brenner was an Associate Research Fellow at Pfizer where he led the islet biology and in vivo pharmacology in the CVMED Target Exploration Unit before assuming the role of Head of the Insulin Resistance Group.Company Description: iBio is a cutting-edge biotech company leveraging AI and advanced computational biology to develop next-generation biopharmaceuticals for cardiometabolic diseases, obesity, cancer and other hard-to-treat diseases. By combining proprietary 3D modeling with innovative drug discovery platforms, iBio is creating a pipeline of breakthrough antibody treatments to address significant unmet medical needs. iBio's mission is to transform drug discovery, accelerate development timelines, and unlock new possibilities in precision medicine.

Support the Institute today. https://givenow.nova.edu/the-institute-for-neuro-immune-medicine-inim-2025   In this episode, we compile selected highlights from the most impactful podcasts of 2025, featuring insights and clinical perspectives from leading experts, including Dr. Richard C. Deth, Dr. Marc Kesselman, Dr. Nancy Klimas, Dr. Payam Hakimi, and Dr. Philip DeFina. Together, they address critical topics such as ME/CFS, Long COVID, and neuroinflammation. This episode also highlights key themes frequently explored throughout the year, including optimizing metabolic health, the essential role of nutrient-dependent healing, and the impact of environmental toxins and mycotoxins on the body. The experts further share insights into homeopathy, post-traumatic symptoms following neuroinflammation, and the biological and lifestyle factors that help protect brain health. Ultimately, this compilation underscores the importance of communication, trust, and patient-centered relationships in delivering effective care and supporting meaningful healing outcomes. Dr. Richard Deth is a molecular neuroscientist at Nova Southeastern University, where he has worked since 2014 after 38 years at Northeastern University. His research focuses on brain disorders like autism, exploring neurodevelopment, aging, attention, and learning. He studies neurons' metabolic features, particularly the antioxidant glutathione (GSH), its role in methylation, and epigenetic regulation. Dr. Deth investigates how casein and gluten-derived opioid peptides impair cysteine absorption, affecting antioxidant levels and epigenetics. His current work examines oxidative stress, inflammation, and the anti-inflammatory potential of cobinamide, a vitamin B12 precursor. LinkedIn: https://www.linkedin.com/in/richard-deth-2383175/    Dr. Marc Kesselman is the chair and associate professor at the Department of Internal Medicine at Dr. Kiran C. Patel College of Osteopathic Medicine. He is also the chief of the Division of Rheumatology at Nova Southeastern University. Dr. Kesselman received his medical degree from Des Moines University College of Osteopathic Medicine and has been in practice for more than 20 years.  LinkedIn: https://www.linkedin.com/in/marc-m-kesselman-d-o-facoi-facc-facr-6491479/    Dr. Nancy Klimas, a clinical immunologist by training, is the director of the Institute for Neuro-Immune Medicine who has allotted her life to helping other people find cures for their complex illnesses that were once considered helpless. She works with her fellow medical experts in researching and analyzing the deeper causes of such diseases, particularly on the neuro-immunity side, to provide the best option suited for every single case or story they handle.   LinkedIn: https://www.linkedin.com/in/nancy-klimas-49255178/ Instagram: https://instagram.com/nancyklimas     Twitter: https://x.com/ngklimas?s=20      Dr. Payam Hakimi is the Medical Director of Body of Harmony in Beverly Hills, CA, and Miami, FL, offering a range of services including Functional Medicine, Anti-aging Medicine, Hormone Replacement Therapy, Clinical Homeopathy, and IV Nutrition Therapy. A board-certified Doctor of Osteopathic Medicine, Dr. Hakimi blends conventional and complementary medicine with a personalized approach to care. He earned his DO from Western University of Health Sciences, completed his residency at LAC+USC, and served as Chief Resident and Assistant Clinical Professor at USC Keck School of Medicine. A national leader in homeopathic education, Dr. Hakimi is a senior faculty member at the CEDH and the only U.S. physician to consistently lecture on homeopathy at medical conferences, sharing his expertise with diverse healthcare audiences. Instagram: https://www.instagram.com/bodyofharmony/ YouTube: https://www.youtube.com/c/bodyofharmony Instagram: https://www.instagram.com/boironusa/ LinkedIn: https://www.linkedin.com/in/drpayamhakimi/ X: https://x.com/Bodyofharmony   Learn more about the Body of Harmony through their website: https://bodyofharmony.com/   Dr. Philip DeFina has over 40 years of experience as a neuropsychologist and cognitive neuroscientist. He is most known for developing novel, groundbreaking treatment protocols for traumatic brain injury, coma, autism spectrum, and PTSD. He is the founder and Chief Scientific Officer of the International Brain Research Foundation (IBRF). Dr. DeFina previously served on the NYU faculty as an associate professor of neurology and psychiatry at the New York University School of Medicine and the Bellevue Hospital Center. He was a forensic neuropsychologist at the Mount Sinai-Elmhurst Hospital Medical Center and was an adjunct professor at the University of Maryland Psychology Department. Dr. DeFina was also the founder and first director of the Fielding Graduate University's Post-Doctoral Clinical Neuropsychology Training Program. Dr. DeFina subsequently co-founded the school neuropsychology training program at Texas Women's University and co-founded the American Board of School Neuropsychology, and was one of the original founding members of the American Board of Pediatric Neuropsychology.   Website: https://ibrfoundation.org/ Facebook: https://www.facebook.com/people/International-Brain-Research-Foundation/100070365733222/ Instagram: https://www.instagram.com/save.a.soldier/ YouTube: https://www.youtube.com/@IBRFinc   Learn more about the International Institute for Brain Enhancement. Website: https://usbrainenhancement.com/ Instagram: https://www.instagram.com/braininstitute.fl/   Haylie Pomroy, Founder and CEO of The Haylie Pomroy Group, is a leading health strategist specializing in metabolism, weight loss, and integrative wellness. With over 25 years of experience, she has worked with top medical institutions and high-profile clients, developing targeted programs and supplements rooted in the "Food is Medicine" philosophy. Inspired by her own autoimmune journey, she combines expertise in nutrition, biochemistry, and patient advocacy to help others reclaim their health. She is a New York Times bestselling author of The Fast Metabolism Diet.   Learn more about Haylie Pomroy's approach to wellness through her website: https://hayliepomroy.com   Instagram: https://www.instagram.com/hayliepomroy  Facebook: https://www.facebook.com/hayliepomroy  YouTube: https://www.youtube.com/@hayliepomroy/videos  LinkedIn: https://www.linkedin.com/in/hayliepomroy/  X: https://x.com/hayliepomroy     Sign up today for our newsletter. https://nova.us4.list-manage.com/subscribe?u=419072c88a85f355f15ab1257&id=5e03a4de7d    This podcast is brought to you by the Institute for Neuro-Immune Medicine. Learn more about us here.   Website: https://www.nova.edu/nim/ Facebook: https://www.facebook.com/InstituteForNeuroImmuneMedicine Instagram: https://www.instagram.com/NSU_INIM/ Twitter: https://www.twitter.com/NSU_INIM