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Think you can crack the science first and worry about CMC when you "need it"? That's exactly how promising therapies die in regulatory limbo while patients keep waiting.Your breakthrough discovery means nothing if it's trapped in CMC chaos. While you're perfecting your molecular mechanism, competitors with inferior science but superior CMC strategy are racing past you to IND filing and ultimately, to patients.In this episode, I, David Brühlmann, your usual host, expose the dangerous delusion that's quietly bankrupting biotech startups: the belief that brilliant science automatically translates to successful drug development. Drawing from years of watching founders burn through millions because they treated CMC as an afterthought, I reveal why the smartest scientific minds often make the most catastrophic business decisions.Here's the hard truth you'll confront in this episode:The $50M Misconception: Why "CMC is just manufacturing" thinking destroys companies before they ever reach Phase II. While you're debating molecular targets, smart founders are building systematic CMC advantages that compress timelines and slash costs. The FDA doesn't care how elegant your science is if you can't demonstrate consistent, scalable manufacturing.The Brutal Mathematics of Delay: Systematic CMC approach: 10-12 months to IND, 85% hit timelines. "Figure it out later" approach: 15 months or more, and a much lower success rate. Every month you delay isn't just burning cash. If your therapy could help 10,000 patients annually, that's 833 people per month who don't get treatment because of preventable delays.Three Founder Myths That Kill Programs: The misconceptions about CMC being "basically just manufacturing," bringing in experts "when we need them," and CDMOs handling "the complicated stuff." Each myth leads to the same outcome: brilliant science trapped by business incompetence.Your Four-Action Emergency Protocol: Stop hoping CMC will work out. Start implementing systematic approaches. I give you four specific actions to execute this week, not someday when you're "ready," but right now while you can still prevent the crisis that kills 40% of biotech programs.The competitive reality: While you're listening to this episode, your biggest competitor just moved closer to IND filing. Maybe they completed process validation. Maybe they locked in analytical methods. The question isn't whether CMC matters. It's whether you'll master it before your competitors do.Next step:
In hour 3, Spadoni and Shasky discuss if they feel CMC is returning to the CMC we saw in 2023 or he has lost a step.
As we live in a “world with devils filled,” the first-century church at Antioch shows us the way forward in faithfulness to Christ and His gospel. CMC and CTC, will you aim for Antioch?
JMToWin from One Week Season walks us through the Week 2 DFS slate from a GPP perspective, shares his top plays at each position, and then builds a DraftKings lineup with Pete using some of his favorite building blocks. In the second half, Youdacao and Bric75 from Run The Sims join to discuss how to leverage sims to build out your Week 2 lineups.
For too long, biotech innovators have viewed biological systems as inherently messy, unpredictable, and full of “black box” mysteries. But what if, armed with the latest digital tools, AI, and cross-disciplinary thinking, you could transform bioprocessing from a series of trial-and-error experiments to a streamlined, proactive design process?Carmen Jungo Rhême is Full Professor at the University of Applied Sciences in Fribourg (HEIA-FR) and Director of the Biofactory Competence Center (BCC). With 17 years in the pharmaceutical industry at companies like Lonza, Merck Serono, UCB Farchim, and CSL Behring, she specializes in bioprocess development, protein purification, scale-up, and technology transfer. Since joining HEIA-FR in late 2023, she has launched research projects tackling antimicrobial resistance, sustainable food production, and bioprocess digitalization.Here are three reasons why this episode is a must-listen:A Blueprint for Scalable Bioprocessing: Carmen reveals the structured, four-phase approach the BCC uses to help startups and established companies alike, from feasibility and risk assessment, to scalable process design, tailored analytics, and seamless tech transfer to GMP manufacturing.The Future-Proof Skill Set: Discover why data management, digital tool adaptability, and systems thinking are non-negotiable skills for biotech professionals in the next five years and how both newcomers and seasoned scientists can level up.Bioprocessing as Design, Not Chaos: Learn how shifting your mindset from reactive to proactive, and from “biology is messy” to “biology is designable,” can unlock robust processes, faster innovation, and truly sustainable solutions.Ready to smarten up your biotech game? Listen in as Carmen and David unpack practical, actionable strategies for mastering modern bioprocessing—no matter your starting point.Connect with Carmen Jungo Rhême:LinkedIn: www.linkedin.com/in/carmenjungoWebsite: www.heia-fr.ch/en/applied-research/bcc/Next step:Book a free consultation to help you get started on any questions you may have about bioprocess development: https://bruehlmann-consulting.com/call
Welcome to the Paint The Medical Picture Podcast, created and hosted by Sonal Patel, CPMA, CPC, CMC, ICD-10-CM.Thanks to all of you for making this a Top 15 Podcast for 5 Years: https://blog.feedspot.com/medical_billing_and_coding_podcasts/Sonal's 16th Season starts up and Episode 2 features a Newsworthy update on the OIG Work Plan for August 2025.Sonal's Trusty Tip and compliance recommendations focus on Proof of Delivery documentation requirements.Spark inspires us all to reflect on resilience based on the inspirational words of Elizabeth Edwards.Checkout the Workshop for Telehealth Playbook for 2025-2026 on: https://kwadvancedconsulting.com/training-education-2/on-demand-webinars/webinar-registration/Paint The Medical Picture Podcast now on:Spotify: https://open.spotify.com/show/6hcJAHHrqNLo9UmKtqRP3XApple Podcasts: https://podcasts.apple.com/us/podcast/paint-the-medical-picture-podcast/id1530442177Amazon Music: https://music.amazon.com/podcasts/bc6146d7-3d30-4b73-ae7f-d77d6046fe6a/paint-the-medical-picture-podcastFind Paint The Medical Picture Podcast on YouTube: https://www.youtube.com/channel/UCzNUxmYdIU_U8I5hP91Kk7AFind Sonal on LinkedIn: https://www.linkedin.com/in/sonapate/And checkout the website: https://paintthemedicalpicturepodcast.com/If you'd like to be a sponsor of the Paint The Medical Picture Podcast series, please contact Sonal directly for pricing: PaintTheMedicalPicturePodcast@gmail.com
We barely survived Week 1 and Mike actually switched his Survivor pick mid-week (never again). Lightning delays, near-upsets, and a Sunday Night miracle later… we're somehow up and sprinting on the Road to $10K. In this episode: Andy Reid shockers, a (maybe) god-tier Herbert, Bills as team of destiny, Dolphins doom, Russ reality, why home favorites matter in Survivor, and the exact bets we've already placed for Week 2 — including a spicy Raiders flyer and a big Bills position. Plus: the contrarian traps to avoid and which teams to “burn early” before the value evaporates. Want our mid-week card? Subscribe to the Substack (free + $5 insider tier for bonus picks): search The Sports Hangover on Substack. Drop a comment with your game and we'll give you a tailor-made read. Chapters 00:00 Cold Open — We survived… barely (and a brutal Survivor switch) 00:52 Cowboys/Titans late-game chaos + Eagles after the lightning 01:38 Chiefs Week 1 shock & the Kelsey/Worthy conspiracy 02:22 New Friday game rules & why it's going away 02:53 Three teams we misread (and why Week 1 lies) 03:20 Herbert unleashed: “Joe Montana or Justin Herbert?” 04:49 Raiders respect: Pats overhyped, Vegas for real? 06:05 Off-season noise ≠ wins (Diggs boat jokes included) 06:19 SNF insanity: Bills comeback and why we turned it off
CMC got a lot of touches, but his health is a secondary concern right now for the 49ers
Almost every corner of modern medicine and sustainable food production today is facing a massive challenge: how do we outpace drug-resistant “superbugs” and create food for a growing population using fewer resources? The answer, it turns out, may come down to how well we understand and control the biomanufacturing processes underpinning these biomaterials and biomolecules.In this episode, David Brühlmann speaks with Carmen Jungo Rhême, Full Professor at the University of Applied Sciences in Fribourg, Switzerland and Director of the Biofactory Competence Center. With years in the pharmaceutical industry at Lonza, Merck Serono, UCB Farchim, and CSL Behring, she now tackles global challenges like antimicrobial resistance, sustainable food, and digitalization. From her beginnings in chemical engineering at EPFL to leading at the nexus of academia and industry, Carmen is helping shape the future of smarter, more robust biotech.Here are three reasons why this episode is a must-listen:Antimicrobial Resistance - Smarter Solutions: Carmen explains how phage therapy, recombinant proteins like endolysins, and smart bioprocess design are helping outmanoeuvre drug-resistant pathogens. In partnership with the University Hospital in Lausanne, her team is developing GMP-ready phage production using quality-by-design methods from mainstream recombinant protein manufacturing, bringing phages back into clinical relevance.From Cheese Whey to Microalgae: Applying pharma-grade principles to food, BCC is turning Swiss cheese by-products into nutrient-rich microalgae, offering a new path for sustainable protein and lipid production while transforming food waste into valuable resources.Digitalization - The Connecting Thread: Mapping and controlling hundreds of process parameters is key to robust, reproducible innovation. Carmen shows how data-driven process characterization links antimicrobial strategies and sustainable food production through the power of digital analytics.Curious about how smarter bioprocesses could help you solve tomorrow's biggest biotech challenges? Tune in to hear how Carmen's approach could transform your perspective on both health and food security.Connect with Carmen Jungo Rhême:LinkedIn: www.linkedin.com/in/carmenjungoWebsite: www.heia-fr.ch/en/applied-research/bcc/Next step:Book a free consultation to help you get started on any questions you may have about bioprocess development: https://bruehlmann-consulting.com/call
Use Promo code "Ron" on Underdog to Play $5 and Get $50 in Bonus Funds!: https://play.underdogfantasy.com/p-ron-stewart2025 Fantasy Football Draft Rankings: https://www.patreon.com/ronstewart2025 Underdog Rankings Upload: https://www.patreon.com/ronstewart1 on 1 Fantasy Advice: https://www.patreon.com/ronstewartIn-Season Weekly Rankings: https://www.patreon.com/ronstewartIn-Season Weekly Waiver FAAB Article: https://www.patreon.com/ronstewartRest of Season Rankings: https://www.patreon.com/ronstewartExclusive Discord Chat: https://www.patreon.com/ronstewartSubscriber Leagues: https://www.patreon.com/ronstewartDynasty Rankings & Tiers: https://www.patreon.com/ronstewartJoin our FREE Discord: (https://discord.gg/2JsBehdA8S)Follow Me on Twitter Here: https://twitter.com/RonStewart_Follow Me on Tik Tok: https://vm.tiktok.com/ZMeJbWgfv/...I'm always looking for editing/graphic design/website building help, email me here if interested: ronstewart.business@gmail.comEmail ronstewart.business@gmail.com for business inquiriesAudio versions of these videos can be found here:Apple Podcast: https://podcasts.apple.com/us/podcast...Spotify: https://open.spotify.com/show/6iUFYKq...Google Podcasts: https://www.google.com/podcasts?feed=...Intro and Outro song is 'Snowcone' by KTXAS. His music can be found here: https://linktr.ee/ktxasTime Stamps:Rookie Receiver Report (0:00)Take a Breath (15:45)SNF Thoughts (19:00)Time to Panic on Ken Walker? (22:00)CMC is inevitable (25:00)Slow Start bengals (25:30)Dylan Sampson (26:45)MIA IND (28:10)GB DET (31:50)LAR HOU (36:45)PIT NYJ (39:40)LVR NE (48:35)TB ATL (53:00)NO ARZ (54:00)WAS NYG (56:25)JAX CAR (58:40)DEN TEN (1:00:00)#UDpartner#fantasyfootballadvice #2025fantasyfootball #fantasyfootballrankings
The 49ers rallied late for a 17-13 comeback victory over the Seattle Seahawks on Sunday at Lumen Field. While San Francisco's defense produced several key performances, a surprising face on offense made the play of the game when third-string tight end Jake Tonges stepped up in George Kittle's injury absence. Matt Maiocco and Jennifer Lee Chan break down the roller-coaster ride that was the 49ers' Week 1 win, from outstanding defense and gritty offense to their erratic special-teams play.--(1:00) 49ers hold on for late win in wild finish(3:00) Tonges delivers with game-winning TD(7:00) Jauan Jennings, George Kittle will have MRIs on injuries(12:00) CMC a main reason 49ers won(17:45) Jennifer details postgame vibe in 49ers' locker room(21:00) 49ers' special teams roller-coaster continues(23:00) How long can Jake Moody remain 49ers kicker?(26:00) Special teams as a whole must be fixed(29:00) Biggest player personnel takeaways from Week 1
A weekly staple on 'The Rich Eisen Show' since 2018, 'Overreaction Monday' is now also an extended podcast with Rich and Chris Brockman debating the latest in the NFL. Today's topics: 1:30 - Josh Allen is NFL's top QB, will repeat as MVP and the Bills will be the AFC's 1-seed 7:30 - Bills/Ravens already the game of the year and was the AFC Championship Game preview 11:00 - Don't sleep on the Chiefs 13:50 - The Russell Wilson era is already over; time for the Giants to start Jaxson Dart 17:25 - Aaron Rodgers has hit fountain of youth and will mirror his '21 MVP season stats 21:15 - The NFC Championship Game will be at Lambeau Field 23:05 - The Colts are AFC South front runners 25:40 - Despite the win, the Bengals' slow start will haunt them again 28:45 - The Lions' championship window closed with Ben Johnson leaving Detroit 30:15 - CMC is back + 49ers injuries = top five SZN coming 32:55 - The Chargers are the team to beat in the AFC West Learn more about your ad choices. Visit podcastchoices.com/adchoices
Aidan is back with three winners and three losers from NFL Week 1—no “moral victories,” just who truly helped or hurt their season outlook!Winners49ers – Gritty road win in Seattle, CMC back in full force despite injuries; late Bosa strip-sack seals it.Bills – Instant classic comeback vs. Ravens; Allen plants an early MVP flag.Chargers – Clean late-game execution vs. the Chiefs in Brazil; Herbert delivers when it mattered most against the big bad bully.LosersFalcons – Missed a statement at home vs. Bucs; Penix era has to cash chances late.Lions – Post–Ben Johnson offense looked stuck in mud at Lambeau; chunk plays missing.Giants – O-line overwhelmed, predictable script, sideline buy-in in question; QB carousel watch begins.Drop your own W/L lists below and tell us what we missed!Subscribe for weekly recaps, instant reactions, and mini breakdowns all season.
A weekly staple on 'The Rich Eisen Show' since 2018, 'Overreaction Monday' is now also an extended podcast with Rich and Chris Brockman debating the latest in the NFL. Today's topics: 1:30 - Josh Allen is NFL's top QB, will repeat as MVP and the Bills will be the AFC's 1-seed 7:30 - Bills/Ravens already the game of the year and was the AFC Championship Game preview 11:00 - Don't sleep on the Chiefs 13:50 - The Russell Wilson era is already over; time for the Giants to start Jaxson Dart 17:25 - Aaron Rodgers has hit fountain of youth and will mirror his '21 MVP season stats 21:15 - The NFC Championship Game will be at Lambeau Field 23:05 - The Colts are AFC South front runners 25:40 - Despite the win, the Bengals' slow start will haunt them again 28:45 - The Lions' championship window closed with Ben Johnson leaving Detroit 30:15 - CMC is back + 49ers injuries = top five SZN coming 32:55 - The Chargers are the team to beat in the AFC West Learn more about your ad choices. Visit podcastchoices.com/adchoices
Sailors, leave those streamers alone, they do this for a living. We break down how online actions can spill over into the real world. In this week's catch-up, Damon talks getting ready for CMC school and football kick-off, plus we cover pulling the truth out of a Sailor at DRB, the Command Holiday Party, and what not to do during the festivities. We dive into the CNO's first C-NOTE, “Sailors First,” and how far delegation travels when it comes to executing tasking. We also ask: can a Sailor make an impact on the very first day they check into a command? These topics and more are on deck in this episode.
Jason Smith and Mike Harmon open the show updating the Chiefs vs. Chargers game. Then they get into the news that Christian McCaffrey was a non-participant at practice Friday... are the Niners in for another injury-plagued year of CMC? Plus, reactions to the Chicago Sky suspending Angel Reese for a game.See omnystudio.com/listener for privacy information.
On this profit-minded episode, Brad Evans and Nate Lundy throw down dollars on various Week 1 NFL plays. First up, the boys hitch a ride on the PLUS BUS detailing a favorite wager and + money. What does Evans like in the matchup south of the equator? From there, Brad counts down the FADE FIVE, pitching action on Breece Hall, Chase Brown, Matthew Golden, Christian McCaffrey and more. How dumb is he risking real money on CMC? On what specifically? Where did Lundy double down on his idiocy? Where did he join him? The guys also discuss some COLLEGE CASH in BONUS TIME and Brad stretches legs on his #TeamHuevos Parlay Play. Get the entire show in just 30 minutes!
Damon Bruce Plus: Warriors, 49ers, Giants, A’s Bay Area Sports Talk
0:40: Another year, another CMC calf injury? Oh come on.13:20: A lot of national media seems to be picking the Niners as BACK, and even Super Bowl winners22:43: The 49ers crushed the league in ticket sales last year:27:28: “The Black Hole” is headed to Memorial Stadium?32:40: Today in history:
Joe Bond, AJ Applegarth, and Corey Pieper break down the latest Week 1 fantasy football injury news and roster moves, including CMC, Najee Harris, Stefon Diggs, Christian Kirk, Isaiah Likely, and more. Find out who to trust and where to pivot before kickoff. Join Fantasy Six Pack for full rankings, projections, and DFS or betting advice: fantasysixpack.net/plansUse promo code F6PPODS to save 15 percent. Follow the hosts: Joe (@F6P_Joe), AJ (@F6P_AJ), Corey (@copieps)
From 'Stinkin' Truth Podcast' (Subscribe Here): Mark Schlereth continues his "Stinkin' Truth Tour," with today's stop - The Bay. He chats with Matt Barrows of "49ers Plus Minus" to check on CMC's health, Ricky Pearsall's confidence and if the young defense is ready to step up. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
In hour 2, Spadoni and Shasky ask if CMC will be available in Week 1, and Dr. Pandya joins the show to give insight on CMC's injury.
In hour 1, Spadoni and Shasky discuss the report that CMC left 49ers practice with soreness in his calf. A potential huge blow to the 49ers season.
In hour 3, Spadoni and Shasky catch up with Bonta on the CMC injury and the Niners season to come.
Spadoni and Shasky discuss CMC popping up on an injury report with the same calf issue. How concerning is this and will he be available for week 1? Bonta Hill joins the show!
Imagine unlocking a world where designing custom proteins is not only feasible - but faster, smarter, and more powerful than ever before, thanks to artificial intelligence.As the promise of programmable biology takes center stage, AI-driven protein engineering is rapidly moving from theoretical dream to industry standard.In this episode, David Brühlmann sits down with Elise de Reus, co-founder of Cradle, whose ground-breaking platform has become a go-to for luminaries at pharma giants, as well as leaders in agriculture and industrial biotech. Elise's journey bridges hands-on scientific discovery with entrepreneurial vision, and she's on a mission to make biology a foundational pillar of a more sustainable and equitable world.Here are three reasons you can't miss this episode:AI Unmasks the Black Box: Elise explains how Cradle's platform isn't just about predictive power - it offers transparency and actionable insights, allowing scientists to see why models perform as they do, and how to interpret and trust their outputs.From Hype to Real-World Impact: You'll hear real examples of AI accelerating everything from pandemic preparedness and antivenom development, to sustainable raw materials - plus candid advice on scaling AI adoption across diverse project teams.Blueprints for Biotech Founders: Elise shares hard-won lessons on transforming scientific innovation into a thriving company, including the counterintuitive power of targeting “mission impossible” challenges and the priceless value of early, unfiltered feedback.Ready to future-proof your protein engineering with generative AI? Press play to take home Elise's practical framework for evaluating tools, overcoming organizational hurdles, and crafting a winning adoption strategy, before the innovation curve pulls away.Wondering how Generative AI is transforming the biotech landscape? From accelerating regulatory workflows to reinventing protein purification, AI is driving breakthroughs across the industry. Explore these standout episodes to hear from experts leading the charge:Episodes 77-78: Cell Factories Explained: How Synthetic Biology and AI Revolutionize Protein Production with Mauro TorresEpisodes 119-120: Innovating Protein Purification Using Synthetic Organelles and AI with Haotian GuoEpisodes 123-124: Manufacturability: Why Most Protein Candidates Fail (And How to Pick Winners Early) with Susan SharfsteinEpisodes 167-168: How Generative AI Is Revolutionizing Biotech Regulatory Compliance with Abhijeet SatwekarConnect with Elise de Reus:LinkedIn: www.linkedin.com/in/elise-de-reus-77b83a24Website: www.cradle.bioNext step:Book a free consultation to help you get started on any questions you may have about bioprocess development: https://bruehlmann-consulting.com/call
The Seahawks are back, and so is Sea Hawkers What If with a season opener that's anything but ordinary. We get into the “Tech War” between King County and the Bay Area, setting the stage for the biggest questions: Can Seattle's revamped offensive line set the tone? Will the rookie factor on San Francisco's defense give Kubiak's offense the edge? How will the Seahawks contain CMC and force Brock Purdy into uncomfortable situations? From chess matches between new coordinators to the battle in the trenches, we cover all the angles that could decide this game. No episode is complete without the voice of the Flock. We share fan wishes and bold predictions from the Sea Hawkers Podcast Discord, including hopes for a dominant run game, a stadium full of Seahawks fans, and a “Purdy Turdy” interception for Julian Love. The crew wraps up with confident score predictions and “What If Super Hawk” scenarios—those game-changing moments we're all hoping to see. Join our Sea Hawkers Podcast Pickem League - free prizes for weekly winners. Support the show Get in the Flock! Visit GetInTheFlock.com Or visit our website for other ways to support the show Subscribe via: Apple Podcasts | Spotify | Google Podcasts | YouTube | TuneIn | RSS Follow us on: Facebook | Twitter Listen on our free app for Android, iOS, Kindle or Windows Phone/PC Call or text: 253-235-9041 Find Sea Hawkers clubs around the world at SeaHawkers.org Music from the show by The 12 Train, download each track at ReverbNation
Welcome to the Paint The Medical Picture Podcast, created and hosted by Sonal Patel, CPMA, CPC, CMC, ICD-10-CM.Thanks to all of you for making this a Top 15 Podcast for 5 Years: https://blog.feedspot.com/medical_billing_and_coding_podcasts/Sonal's 16th Season starts up and Episode 1 features a Newsworthy spotlight on September as Childhood Cancer Awareness Month.Sonal's Trusty Tip and compliance recommendations focus E/M scrutiny from a payor. Spark inspires us all to reflect on resilience based on the inspirational words of Shane Koyczan.Childhood Cancer Awareness Month:Website: https://www.stjude.org/get-involved/other-ways/childhood-cancer-awareness-month.htmlPaint The Medical Picture Podcast now on:Spotify: https://open.spotify.com/show/6hcJAHHrqNLo9UmKtqRP3XApple Podcasts: https://podcasts.apple.com/us/podcast/paint-the-medical-picture-podcast/id1530442177Amazon Music: https://music.amazon.com/podcasts/bc6146d7-3d30-4b73-ae7f-d77d6046fe6a/paint-the-medical-picture-podcastFind Paint The Medical Picture Podcast on YouTube: https://www.youtube.com/channel/UCzNUxmYdIU_U8I5hP91Kk7AFind Sonal on LinkedIn: https://www.linkedin.com/in/sonapate/And checkout the website: https://paintthemedicalpicturepodcast.com/If you'd like to be a sponsor of the Paint The Medical Picture Podcast series, please contact Sonal directly for pricing: PaintTheMedicalPicturePodcast@gmail.com
For decades, protein design has hinged on painstaking rounds of wet lab mutagenesis and trial-and-error, a process limited not by human ingenuity, but by time and complexity. Yet as the biotech field seeks faster, greener, and more effective solutions for therapeutics and industrial applications, the next leap might not come solely from the lab bench.In this episode, host David Brühlmann explores the frontiers of AI-driven protein engineering with Elise de Reus, co-founder of Cradle. Elise's journey weaves together a passion for DNA, real-world impact from the dairy industry to synthetic biology, and high-throughput experience at Zymergen. Now, at the helm of Cradle, she is bridging cutting-edge computational models with experimental validation, making biology programmable and accelerating the path from idea to functional protein.Here are three reasons this episode is essential listening:AI Makes Biology Programmable: Generative AI platforms like Cradle can intelligently design protein variants by learning from evolutionary trends and your own project data, enabling smarter, faster iterations and optimizing for stability, activity, and manufacturability - simultaneously.Limited Data? No Problem: While traditional approaches have stumbled over small, “short and fat” datasets, new generative AI models can effectively update their understanding with as little as a 96-well plate per round, democratizing high-impact protein design for startups, academia, and industry alike.The Future is Human + Machine: Even as algorithms advance, Elise stresses the irreplaceable value of wet lab validation. Cradle's hybrid approach, integrating experimental feedback with algorithmic prediction, ensures reliable, scalable results and empowers multidisciplinary teams to unlock first- and best-in-class solutions.Want to see how you can leverage AI to simplify and accelerate your own protein engineering projects? Don't miss this episode to hear how Elise and Cradle are transforming the pace - and possibilities - of biotech.Curious how Generative AI is reshaping biotech? From streamlining regulatory compliance to transforming protein purification, AI is changing the game. Dive into these standout episodes to explore the cutting edge of innovation in biotech:Episodes 77-78: Cell Factories Explained: How Synthetic Biology and AI Revolutionize Protein Production with Mauro TorresEpisodes 119-120: Innovating Protein Purification Using Synthetic Organelles and AI with Haotian GuoEpisodes 123-124: Manufacturability: Why Most Protein Candidates Fail (And How to Pick Winners Early) with Susan SharfsteinEpisodes 167-168: How Generative AI Is Revolutionizing Biotech Regulatory Compliance with Abhijeet SatwekarConnect with Elise de Reus:LinkedIn: www.linkedin.com/in/elise-de-reus-77b83a24Website: www.cradle.bioNext step:Book a free consultation to help you get started on any questions you may have about bioprocess development: https://bruehlmann-consulting.com/call
(0:00) Texas & Arch Manning lose to Ohio State, Packers S.B.o.B with Parsons? (26:21) Cowboys upset or Eagles blowout, Must-Win for Belichick & UNC? (41:09) Tyreek Hill not named Dolphins team captain (46:00) Coach's Picks, Will the Cowboys be better without Micah Parsons? (01:06:52) Arch Manning's struggles, Jayden Daniels named top young QB (01:21:59) Eagles want “Contributions over credit”, Like this mentality? (01:26:13) Things “seemed personal” with Micah & Cowboys, What's the Packers' ceiling? (01:49:23) Stock Up, Stock Down: Alabama, Carson Beck, and LSU (01:59:11) Caleb Williams' sophomore expectations, Big season for CMC? (02:07:05) Guaranteeing an Eagles blowout vs. Cowboys? Learn more about your ad choices. Visit podcastchoices.com/adchoices
Damon and Damo are back, calling an audible after a guest no-show (don't worry — he's safe and sound). The conversation kicks off with Damo asking how Chiefs really view CMCs, followed by his response to a negative Facebook comment about him. Fresh off an appearance on Theresa Carpenter's Stories of Service podcast, Damo challenges Damon to reflect on how far he's come. The guys tackle a listener's suggestion to revamp the PFA with firefighting readiness tasks, react to the disappointing update in the death of CSSN Angelina Resendiz, and weigh the pros and cons of being stationed in your hometown for your first tour. Damon shares his first impressions of CMC turnover, and the two debate whether there's ever enough time to be a “bystander hero.” They also break down the viral wrestling match between Raja Jackson and Army vet Syko Stu, laugh through the strangeness of dreams about cheating partners, and highlight Admiral Caudle's first All Hands Call aboard USS Truman with a “Sailor First” message. A few Reddit posts spark some impromptu motivation, the Cowboys trading Micah Parsons shakes up NFL fans, and Damon's “Do Better” of the week takes aim at tariffs. These and more topics are covered in this episode. To have your “Do Better” reviewed on a future episode, please get in touch with us at ptsfpodcast@gmail.com Keep up with the ‘Permission to Speak Freely' podcast on our social media and YouTube - https://linktr.ee/Ptsfpodcast Links and more from this episode: Cheekz Adult Diapers - https://shop.alohaseniorhomecare.com Stories of Service (Ep. 220) (Feat. Damo) - https://www.youtube.com/live/Z3-ij10q5_g?si=4IjCkDdEiXJ3rOLC Angelina Resendiz Update - https://www.13newsnow.com/article/news/national/military-news/norfolk-sailor-resendiz-cause-manner-death-undetermined-virginia-medical-examiner/291-411f1c4d-21f1-4736-9a42-0779566161b8 CNO All Hands (Full Video) - https://youtu.be/yvkcqJQq6TQ?si=DpwX79bW-8emmRSu Leading Outward Podcast (Apple Link) - Leading Outward Book of the week: Set Boundaries, Find Peace (Nedra Glover Tawwab) - https://www.nedratawwab.com/set-boundaries-find-peace Additional Credits: PTSF “Theme Music” - Produced by Lim0
Live from Love & War in Plano, Texas, the Donkey's Den Podcast dives into the blockbuster NFL news that has the sports world buzzing. The hosts break down the shocking trade that sent superstar Micah Parsons from the Dallas Cowboys to the Green Bay Packers. They analyze the massive deal, which netted the Cowboys Pro Bowl defensive tackle Kenny Clark and two first-round picks in exchange for Parsons, who signed a historic four-year, $188 million contract. The conversation heats up with a brand-new quote from Jerry Jones, who hinted, "Nothing says we can't use some of those picks right now to go get somebody," leading to wild speculation about a potential trade for Myles Garrett.With fantasy football season in full swing, the guys provide an arsenal of tips and sleepers for your upcoming draft. One host reveals his first five draft picks, including Bijan Robinson, O'Marion Hampton, and Jaylen Waddle. The episode is packed with strategy, highlighting players to avoid like CMC and Stefon Diggs , and value picks to target, such as Nico Collins, George Pickens, and third-year receiver Jackson Smith-Njigba. The biggest takeaway for fantasy managers this year is the "rookie running back phenomenon," with a strong recommendation to get at least one of the top rookies on your team.Finally, the crew crowns a new "Donkey of the Week": Rajah Jackson, son of UFC legend Rampage Jackson. The hosts detail a shocking incident at an amateur pro wrestling event where Jackson, responding to a scripted stunt, legitimately slammed a wrestler and punched him until he was unconscious in the ring.The Donkey's Den Podcast is produced by JVM Productions and distributed by iDream Media. We are powered by the iDream Media Foundation, Inc., a non-profit dedicated to helping individuals share their stories and amplify their dreams through podcasting. Learn more at www.idreammediafoundation.com.
Join Seth Woolcock and Derek Brown as they answer all of your fantasy football questions LIVE on Twitch at twitch.tv/fantasypros Timestamps: (May be off due to ads) Intro - 0:00:00 Adam Thielen Breakdown - 0:02:59 Jalen Coker Breakdown - 0:08:10 FantasyPros on Twitch - 0:15:13 Joe Mixon - 0:16:24 Trading for Austin Ekeler - 0:18:44 Best Draft Spot in 2025 - 0:20:31 Targets at Pick 12 - 0:23:52 Trading Travis Kelce for TE and RB Support - 0:26:12 Trophy Smack Giveaway - 0:28:05 Draft Slot Decisions - 0:30:45 CMC vs. Nico Collins - 0:32:34 Matthew Golden vs. Tre Harris - 0:38:50 Jacory Croskey-Merritt Breakdown - 0:41:40 Rashee Rice Breakdown - 0:44:45 Rapid Fire Chat Q&A - 0:47:47 Outro - 0:50:41 Helpful Links: Draft Assistant - Get live support during your fantasy football draft with the Draft Assistant. Connect the Draft Assistant to your draft and get real-time suggestions based on expert rankings, team needs, and positional scarcity. Get the most value out of every pick in your fantasy football draft with the Draft Assistant. Learn more at fantasypros.com/assistant or download our Fantasy Football Draft Wizard app on Google Play or App Store. Draft Simulator - Master your draft strategy by testing it out in minutes using our Draft Simulator. The Draft Simulator allows you to practice quick and fun, realistic mock drafts based on your league settings in minutes. Sync your league for FREE and try it today at fantasypros.com/mock. Follow us on Twitch - The team here at FantasyPros is taking questions all week, every week on Twitch. We've got exclusive live content there every single weekday. Follow us on Twitch at twitch.tv/fantasypros and never miss a stream! Discord – Join our FantasyPros Discord Community! Chat with other fans and get access to exclusive AMAs that wind up on our podcast feed. Come get your questions answered and BE ON THE SHOW at fantasypros.com/chat Leave a Review – If you enjoy our show and find our insight to be valuable, we’d love to hear from you! Your reviews fuel our passion and help us tailor content specifically for YOU. Head to Apple Podcasts, Spotify, or wherever else you get your podcasts and leave an honest review. Let’s make this show the ultimate destination for fantasy football enthusiasts like us. Thank you for watching and for showing your support – https://fantasypros.com/review/ BettingPros Podcast – For advice on the best picks and props across both the NFL and college football each and every week, check out the BettingPros Podcast at bettingpros.com/podcast, our BettingPros YouTube channel at youtube.com/bettingpros, or wherever you listen to podcasts.See omnystudio.com/listener for privacy information.
Send us a textIf you draft running backs on vibes, you're playing with fire. Today we tier every fantasy RB for 2025—who can realistically finish RB1 and who's just name value. We debate Bijan vs Gibbs, how much to trust CMC's health, whether Derrick Henry in BAL still has league-winning juice, why A-Chan is all about QB health, and the best value/volume targets (Kyren, Chase Brown, Josh Jacobs, Jonathan Taylor, Kamara, Kenneth Walker, Chuba, Swift, Pacheco, RJ Harvey, TreVeyon Henderson, Omarion Hampton, James Conner, Breece Hall and more). Plus, real draft-room tactics: when to pivot tiers, handcuff logic, and WR-heavy room counterpunches.
Damon Bruce Plus: Warriors, 49ers, Giants, A’s Bay Area Sports Talk
1:52: NFL fashion to discuss: the rivalry jerseys have dropped25:05: Important follow-up: how big is the 49ers-Seahawk rivalry? And what about the Rams?33:43: What did we learn from the NFL preseason?45:15: Looking at the tiers of teams in the NFC:1:01:27: Hopefully Brian Robinson will stop Kyle Shanahan from overusing CMC:1:11:14: Today in history:
What's the secret to turning a cutting-edge scientific breakthrough into a commercial biotech success?For every inspiring lab discovery, countless prototypes stall before ever reaching the market. The barriers? Securing the right beta testers, outmanoeuvring industry giants, and building teams who understand not just the science, but the user experience from bench to bedside.In this episode of the Smart Biotech Scientist Podcast, David Brühlmann welcomes Chervee Ho, CEO & Co-Founder of BioChromatographix International. Chervee isn't just developing breakthrough column technologies - she's navigating the trenches of commercialization, from resource-stretched startups to partnering with risk-averse manufacturers. With hands-on experience turning innovative science into robust data and real-world adoption, Chervee shares candid lessons from her journey building a biotech company from the ground up.Here are three reasons you can't miss this episode:From Lab Bench to Market: Learn why finding the right beta testing partner is less about luck and more about networking, shared goals, and mutual resource investment - and why a methodical, step-by-step approach beats wishful thinking every time.Winning Against the Big Players: Discover how niche focus, third-party validation, and scientific partnership allow startups like BioChromatographix International to carve out space - even when competing against chromatography industry giants.The Human Factor: Chervee reveals why startup success is all about mindset - resilience, adaptability, and startup “muscle” - far more than specific credentials. If you want to build a team ready for the marathon of commercialization, don't miss these culture insights.Ready to level up your biotech commercialization strategy? Tune in and hear how to accelerate your technology from concept to clinic - without losing focus, funds, or your sanity.Connect with Chervee Ho:LinkedIn: www.linkedin.com/in/cherveehoWebsite: www.biochromatographix.comNext step:Book a free consultation to help you get started on any questions you may have about bioprocess development: https://bruehlmann-consulting.com/call
In their final best ball livestream of the preseason, Tom Strachan and Andrew Erickson go through their player shares and talk about the guys they have planted their flags on the most throughout draft season! Timestamps: (May be off due to ads) Intro - 0:00:00 Terry McLaurin Contract Extension - 0:00:40 Jakobi Meyers Trade Request - 0:03:44 Barkley or Nabers in a Keeper League? - 0:07:20 CMC or Chase Brown? - 0:08:20 Bijan and change for Omarion Hampton + Picks? - 0:10:17 What Should I Do At the 1.03? - 0:12:20 Twitch Livestream Schedule - 0:14:20 Our Most-Rostered Quarterbacks - 0:14:55 Our Most-Rostered Running Backs - 0:20:45 Drafters Promo - 0:24:55 Rate My Team - 0:30:00 Drop Matthew Golden or Rome Odunze for Michael Pittman? - 0:32:16 Rate My Team - 0:32:54 Josh Jacobs, Jonathan Taylor or Kyren Williams? - 0:34:10 Rate My Team - 0:34:40 First Best Ball Draft, How Did I Do? - 0:35:05 FantasyPros Best Ball Draft Kit - 0:36:30 Our Most-Rostered Wide Receivers - 0:37:00 Our Most-Rostered Tight Ends - 0:43:30 Twitch Schedule - 0:46:30 Best Late-Round RBs for 2025? - 0:47:03 14 Team League - Who Do I Pair With Bijan Robinson? - 0:50:40 Our Notable Best Ball Fades - 0:52:21 Listener Best Ball Draft Reviews - 0:56:20 Helpful Links: Draft Assistant - Get live support during your fantasy football draft with the Draft Assistant. Connect the Draft Assistant to your draft and get real-time suggestions based on expert rankings, team needs, and positional scarcity. Get the most value out of every pick in your fantasy football draft with the Draft Assistant. Learn more at fantasypros.com/assistant or download our Fantasy Football Draft Wizard app on Google Play or App Store. Draft Simulator - Master your draft strategy by testing it out in minutes using our Draft Simulator. The Draft Simulator allows you to practice quick and fun, realistic mock drafts based on your league settings in minutes. Sync your league for FREE and try it today at fantasypros.com/mock. Drafters - Draft now in the Drafters Main Event - it’s $20 to enter with a $500K grand prizeNew users – use code FANTASYPROS for a 100% deposit match up to $100Sign up today at drafters.com/refer/fantasypros Follow us on Twitch - The team here at FantasyPros is taking questions all week, every week on Twitch. We've got exclusive live content there every single weekday. Follow us on Twitch at twitch.tv/fantasypros and never miss a stream! Discord – Join our FantasyPros Discord Community! Chat with other fans and get access to exclusive AMAs that wind up on our podcast feed. Come get your questions answered and BE ON THE SHOW at fantasypros.com/chat Leave a Review – If you enjoy our show and find our insight to be valuable, we’d love to hear from you! Your reviews fuel our passion and help us tailor content specifically for YOU. Head to Apple Podcasts, Spotify, or wherever else you get your podcasts and leave an honest review. Let’s make this show the ultimate destination for fantasy football enthusiasts like us. Thank you for watching and for showing your support – https://fantasypros.com/review/ BettingPros Podcast – For advice on the best picks and props across both the NFL and college football each and every week, check out the BettingPros Podcast at bettingpros.com/podcast, our BettingPros YouTube channel at youtube.com/bettingpros, or wherever you listen to podcasts.See omnystudio.com/listener for privacy information.
Welcome to the Paint The Medical Picture Podcast, created and hosted by Sonal Patel, BA, CPMA, CPC, CMC, ICD-10-CM.Thanks to all of you for making this a Top 15 Podcast for 4 Years: https://blog.feedspot.com/medical_billing_and_coding_podcasts/Sonal's 15th Season starts up and Episode 17 features Newsworthy updates on the month's fraud, waste, and abuse cases. Spark inspires us all to reflect on hopes and aspirations based on the inspirational words of Rupi Kaur.Paint The Medical Picture Podcast now on:Spotify: https://open.spotify.com/show/6hcJAHHrqNLo9UmKtqRP3XApple Podcasts: https://podcasts.apple.com/us/podcast/paint-the-medical-picture-podcast/id1530442177Amazon Music: https://music.amazon.com/podcasts/bc6146d7-3d30-4b73-ae7f-d77d6046fe6a/paint-the-medical-picture-podcastFind Paint The Medical Picture Podcast on YouTube: https://www.youtube.com/channel/UCzNUxmYdIU_U8I5hP91Kk7AFind Sonal on LinkedIn: https://www.linkedin.com/in/sonapate/And checkout the website: https://paintthemedicalpicturepodcast.com/If you'd like to be a sponsor of the Paint The Medical Picture Podcast series, please contact Sonal directly for pricing: PaintTheMedicalPicturePodcast@gmail.com
It's NFL cutdown day AND Travis Kelce's engagement is breaking the internet, so of course The Couch GMs had to drop an emergency episode! George and Cody break down the Kelce–Swift news, plus all the biggest roster moves, contracts, and fantasy football impacts heading into Week 1:Terry McLaurin & Trey Hendrickson contract updates
8-25 Dirty Work Hour 2: The NBA Grab bag returns; is CMC and Robinson the best RB combo in NFL?See omnystudio.com/listener for privacy information.
In Hour 2, Spadoni and Lubman are joined by NFL insider Brian Baldinger to break down Brock Purdy's struggles last season, Brian Robinson Jr, CMC's usage and more!
95.7 the Game NFL insider Brian Baldinger joins the Morning Roast with Spadoni and Lubman to chat about Brock Purdy's role in making the receving core, the Brian Robinson Jr. trade and CMC's usage as the No. 1 back
Every year, cutting-edge biomedical technologies are left stranded in the lab, not for lack of innovation, but because they miss the crucial leap from technical performance to genuine industry adoption. The gap between scientific brilliance and commercial success is deceptively simple: deeply understanding and building for your customer's real-world pain points.In this episode, David Brühlmann welcomes Chervee Ho, CEO & Co-Founder of BioChromatographix International. With a background at the intersection of biotechnology and commercial strategy, Chervee has helped reshape how startups approach product development to actually get adopted in conservative markets. From her early days in biotech to launching Singapore's next-generation monolithic chromatography company, Chervee advocates for honest conversations, real customer feedback, and an unflinching commitment to building solutions that people want - not just what scientists think they need.Here are three reasons you can't afford to miss this conversation:Commercial Thinking from Day One: Technical superiority is just the start; Chervee reveals how embedding commercial strategy from the earliest stages, long before the product is ‘perfect', ensures your innovation will actually be used. Start with end-user needs and map backward.Designing for Adoption, Not Just Performance: Don't fall in love with your tech. Discover how BioChromatographix adopted a customer-centric “design for adoption” approach, integrating products into current workflows, minimizing disruption, and collecting real-life feedback that shaped commercial-ready solutions.Bridging the Science-to-Market Divide: Learn how continuous customer engagement, ruthless validation of pain points, and smart use of public data (even while protecting IP) can transform a great idea into a market-ready, trust-building product.Ready to close the gap between invention and adoption? Tune in to discover why commercial thinking isn't just for the sales team and how it's the secret weapon for any biotech scientist wanting to make a lasting impact.Don't just innovate - get your technology into the hands of those who need it most.Connect with Chervee Ho:LinkedIn: www.linkedin.com/in/cherveehoWebsite: www.biochromatographix.comNext step:Book a free consultation to help you get started on any questions you may have about bioprocess development: https://bruehlmann-consulting.com/call
8-25 Dirty Work Hour 2: The NBA Grab bag returns; is CMC and Robinson the best RB combo in NFL?See omnystudio.com/listener for privacy information.
It's officially Redraft SZN people!
Brian Robinson Jr. just got traded to the 49ers, and Jeff breaks down what this move means for fantasy football. Does Robinson carve out a role in one of the league's most productive run schemes, or is he just another body behind Christian McCaffrey? Jeff dives into how this impacts Robinson's value, what it means for CMC's workload, and whether Isaac Guerendo is still worth stashing. Plus, he breaks down the remaining pieces in Washington and how to handled the Commanders RBs in fantasy football drafts. Get Jeff's content: FTN Fantasy
Gary Parrish is in-studio to open the show and we hit on his thoughts on the University of Memphis and all of our shows being out there broadcasting earlier in the week, his conversation with Ed Scott, what he took from their interview, where Tigers Athletics will be in 5 years and more (6:36). Jay Croucher from NBC Sports Fantasy Football Happy Hour joins the show to talk NFL and Fantasy Football including his takes on a player worth taking a flyer on, someone who is being undervalued in drafts, someone who is being overrated in drafts as well as the running back spots and what to do with CMC, Saquon Barkley and Jonathan Taylor (35:15).We'll finish up talking NFL Preseason, College Football Week 0, and High School Football in Memphis (1:22:02). Host: Chris VernonCo-Hosts: Jon Roser, Devin WalkerGuests: Gary Parrish, Jay CroucherTechnical Director: Jaylon Wallace Associate Producer: Jena Broyles
The 49ers began their second joint practice of the NFL preseason in Las Vegas much like their first week, undermanned. Undeterred, they fielded enough players against the Raiders to see some progress from last week. "49ers Talk" hosts Matt Maiocco and Jennifer Lee Chan break down which players were making the biggest impact in the second week of preseason and discuss two emerging rookies on both sides of the ball already making a case for regular-season minutes. Also, Matt and Jennifer update San Francisco's expansive injury room and share Kyle Shanahan's strategy for getting his starters some live reps throughout the rest of the preseason.--(1:00) 49ers in Las Vegas for Week 2 of preseason(3:00) CMC seems back to his normal self; coaches and players vouch(6:00) 49ers' expansive injury updates(11:25) Two rookies on both sides of the ball making cases for regular-season playing time(38:00) How Kyle Shanahan will play veterans for rest of preseason