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Its Week 14 in the NFL, and the 49ers finally have reached their bye. As San Francisco players rest and recuperate, "49ers Talk" co-hosts Matt Maiocco and Jennifer Lee Chan take a pulse on the 49ers' season with just four regular-season games left. Jennifer, Matt, and later Greg Papa, discuss if Kyle Shanahan's current coaching staff is his best yet, and if that makes him a strong candidate for his first NFL Coach of the Year award. They also detail the 49ers' latest injuries and roster additions, then discuss if Christian McCaffrey's public support of Roger Craig can convince the Pro Football Hall of Fame committee to induct the legendary 49ers running back.--(2:00) How wind vs. Browns impacted Shanahan's decisions(3:00) 49ers injury updates, possible replacements(11:00) Could Eric Kendricks contribute to 49ers' defense after LB injuries?(15:00) Former 49ers RB Roger Craig announced as one of three finalists in senior category for Pro Football Hall of Fame(17:00) CMC offers public support for Craig's possible induction(24:00) Greg Papa on the 49ers being superbly coached in all three phases this season(28:00) Is this Shanahan's best coaching staff as a whole in his time with the 49ers?(33:00) It wouldn't shock Papa if Kendricks becomes MIKE linebacker to end the season(40:00) Could we possibly see two 49ers RBs enter HOF in the same year? (Gore, Craig) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Join Ryan Wormeli and Pat Fitzmaurice as they tackle YOUR questions LIVE on Discord on the 1st Tuesday evening of each month at 5 PM ET at fantasypros.com/chat. The fellas break down some changes to the dynasty trade value chart before diving into your questions in the second half of the show! Timestamps: (May be off due to ads) Intro - 0:00:00 QB Ranking Changes - Drake Maye - 0:03:20 JJ McCarthy - 0:08:45 Reality Sports Online - 0:12:50 RB Ranking Changes - Omarion Hampton, Breece Hall - 0:13:45 WR Ranking Changes - JSN, George Pickens, Christian Watson - 0:18:47 TE Rankings Changes - Loveland, Terrance Ferguson, Isaiah Likely - 0:26:39 FantasyPros Trade Analyzer - 0:31:18 What To Do With Marshawn Lloyd and Jordan Mason - 0:23:26 Is My Roster Ready to Win? - 0:35:18 Loaded at WR, but Struggling at RB - 0:38:52 Rebuilding, but what do I do at QB? - 0:43:50 FantasyPros Discord - 0:49:13 Am I Overpaying for Brock Bowers? - 0:49:43 Sutton + Picks for Darnold and Waddle? - 0:53:25 Picks for CMC & Waddle? - 0:54:30 Which Keeper for 2026? - 0:55:19 Which Value QB Should I Trade Addison For? - 0:56:47 Addison & Two 26 1st's for Justin Jefferson - 0:58:13 When Should Dynasty Trade Deadlines Be? - 1:00:11 Jaylen Warren & Chris Godwin for a 2026 1st? - 1:02:36 Is This The Worst It Gets for Monangi? - 1:02:50 Helpful Links: Reality Sports Online - By now, most of you have probably heard of Reality Sports Online, the powerful Fantasy Sports platform where Owners get to build and manage their Fantasy team like an NFL General Manager. But, the question is, have you tried it? It’s time to go see what all the buzz in the dynasty community is about. If you like what you see, use the promo code "FANTASYPROS" to receive a 10% discount on your team or league today! Fantasy Just Got Real at RealitySportsOnline.com. Dynasty Rookie Draft Simulator - Our Dynasty Rookie Draft Simulator lets you complete a mock in minutes with no waiting between picks! Customize your league settings to match your league’s exact format. Premium subscribers can test trade scenarios by mocking with their traded draft picks. Prepare for rookie drafts AND dynasty startup drafts in one place! Use the Dynasty Rookie Draft Simulator to dominate your rookie draft today at fantasypros.com/simulator! Trade Analyzer - Evaluate trades with confidence using FantasyPros' Trade Analyzer. Instantly see the impact of trades on your team and get expert recommendations. Whether you're making a 2-for-1 deal or swapping a couple draft picks for that stud who will help you win now, the Trade Analyzer will help you optimize your roster and make smarter decisions. Try the Trade Analyzer today at fantasypros.com/myplaybook or on the Fantasy Football My Playbook app and dominate your league! Join us on Discord - Join our FantasyPros Discord Community! Chat with other fans and get access to exclusive AMAs that wind up on our podcast feed. Come get your questions answered and BE ON THE SHOW at fantasypros.com/chatSee omnystudio.com/listener for privacy information.
Welcome to the Paint The Medical Picture Podcast, created and hosted by Sonal Patel, BA, CPMA, CPC, CMC, ICD-10-CM.Thanks to all of you for making this a Top 15 Medical Billing & Coding Podcast for 5 years on Feedspot.Sonal's 16th Season starts up and Episode 14 features a Newsworthy update on World AIDS Day.Sonal's Trusty Tip and compliance recommendations focus on a new Medicare hospice outpatient services edit.Spark inspires us all to reflect on resilience based on the inspirational words of Marcus Aurelius.Paint The Medical Picture Podcast now on:Spotify: https://open.spotify.com/show/6hcJAHHrqNLo9UmKtqRP3XApple Podcasts: https://podcasts.apple.com/us/podcast/paint-the-medical-picture-podcast/id1530442177Amazon Music: https://music.amazon.com/podcasts/bc6146d7-3d30-4b73-ae7f-d77d6046fe6a/paint-the-medical-picture-podcastFind Paint The Medical Picture Podcast on YouTube: https://www.youtube.com/channel/UCzNUxmYdIU_U8I5hP91Kk7AFind Sonal on LinkedIn: https://www.linkedin.com/in/sonapate/And checkout the website: https://paintthemedicalpicturepodcast.com/If you'd like to be a sponsor of the Paint The Medical Picture Podcast series, please contact Sonal directly for pricing: PaintTheMedicalPicturePodcast@gmail.com
Post-Thanksgiving vibes in the bomb shelter! Dan and Frank swap holiday stories (Easton–P'burg memories and a new family baby on the way), then crank up the Hot Stove: the Mets' infield shuffle (Simeon for Nimmo talk), what it could mean for Tucker/Bellinger/Realmuto targets, plus the Phillies' quiet start.College football hits Rivalry Week: Texas–A&M, conference title games on deck, and who's really got a path in the new 12-team playoff.Then a full NFL Week 12 whiparound:Chiefs 23, Colts 20 (OT): KC escapes to keep the playoff door cracked.Bears 31, Steelers 28: Chicago steals one; NFC North stays spicy.Patriots 26, Bengals 20: Drake May keeps stacking wins.Ravens 23, Jets 10; Seahawks 27, Titans 24; Packers 27, Vikings 13Lions 34, Giants 27: Jamir Gibbs goes video-game mode late.Jaguars 27, Cardinals 24; Browns 24, Raiders 10; Falcons 24, Saints 10Rams 34, Bucs 7: LA looks hotter by the week.49ers 20, Panthers 9: Turnovers galore, CMC cleans it up.Cowboys 24, Eagles 21: Down 21–0, Dallas storms back—Pickens shines, Dak cooks.Plus: pick standings, lone-wolf chaos, and the Survivor Pool down to three (could this be the week it ends?).Special Thanks to:Fox Brothers Alarms - https://foxbrothersalarms.com First Baptist church of Phillipsburg NJ http://www.fbcpburg.org/
The 49ers (8-4) head into Week 13 looking for their third straight win against a tough Browns (3-8) defense. San Francisco's defense is playing its best football of the season, forcing five turnovers in the last two games and showing major improvement in coverage and tackling.The matchup centers on the quarterbacks. Shedeur Sanders flashed in his debut but still struggled with accuracy and rhythm. With a weak run game and unreliable receivers, the 49ers can force him into mistakes if they stay disciplined.Brock Purdy must rebound after a three-INT performance and now faces the NFL's No. 2 pass defense, led by Myles Garrett, who's chasing the sack record. Cleveland allows just 132 passing yards per game at home, so the 49ers will need to lean on CMC, George Kittle, and Jauan Jennings in the short game to take advantage of the Browns' tackling issues and slow down their pass rush.Visit Sports Spyder for up to date 49ers content: https://sportspyder.com/nfl/san-francisco-49ers/newsFollow us on Twitter @49ers_AccessFollow us on Instagram @49ers.AccessSeatGeek: “49ERSACCESS” for $20 off your first purchase!
The 49ers are entrenched in the final NFC playoff spot as they prepare to face the Cleveland Browns. However, with low temperatures, high-winds, and possible perception forecast for Sunday's matchup, holding onto that precious wild card spot might be more complicated. Having lost their previous contest in Cleveland under similar conditions in 2023, San Francisco will be tasked with executing their offense more efficiently this time while mitigating current NFL sack leader Myles Garrett. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss Brock Purdy's regression last week against the Panthers and how he and the 49ers' offense can minimize mistakes against familiar obstacles in inclement weather and a formidable pass-rush. Also, Matt and Jennifer provide injury updates, surprising takes on a San Francisco offensive line playing well under-the-radar and where the 49ers might look in the draft. They also praise the evolution of Christian McCaffrey's game during an incredible individual season.--(4:00) Purdy's attributes as a starter -- anticipation, decisiveness, accuracy - were absent on three INTs(9:00) This is the first time Purdy has dealt with significant in-season time off, and he's adjusting(11:00) Will precipitation ahead of the game in Cleveland play a role in the outcome?(18:00) 49ers Injury Updates (Bethune, Okuayinonu, Piñeiro out)(22:00) Myles Garrett will be a handful for Trent Williams and offensive line(24:00) Matt believes the 49ers' OL starters this year might not change next year given their performance(32:00) CMC leads the league in rushing attempts and receptions, and is San Francisco's MVP Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Welcome to the Paint The Medical Picture Podcast, created and hosted by Sonal Patel, BA, CPMA, CPC, CMC, ICD-10-CM.Thanks to all of you for making this a Top 15 Medical Billing & Coding Podcast for 5 years on Feedspot.Sonal's 16th Season starts up and Episode 13 features Newsworthy updates on the month's fraud, waste, and abuse cases. Sonal's Trusty Tip and compliance recommendations focus on a Medicare telehealth update.Spark inspires us all to reflect on resilience based on the inspirational words of Dalai Lama.Paint The Medical Picture Podcast now on:Spotify: https://open.spotify.com/show/6hcJAHHrqNLo9UmKtqRP3XApple Podcasts: https://podcasts.apple.com/us/podcast/paint-the-medical-picture-podcast/id1530442177Amazon Music: https://music.amazon.com/podcasts/bc6146d7-3d30-4b73-ae7f-d77d6046fe6a/paint-the-medical-picture-podcastFind Paint The Medical Picture Podcast on YouTube: https://www.youtube.com/channel/UCzNUxmYdIU_U8I5hP91Kk7AFind Sonal on LinkedIn: https://www.linkedin.com/in/sonapate/And checkout the website: https://paintthemedicalpicturepodcast.com/If you'd like to be a sponsor of the Paint The Medical Picture Podcast series, please contact Sonal directly for pricing: PaintTheMedicalPicturePodcast@gmail.com
From pandemic-speed vaccine deployment to AI-powered process control, what separates hype from real manufacturing transformation?The biotech industry faces a fundamental challenge: how do you maintain rigorous quality standards while accelerating development timelines, personalizing therapies, and adopting transformative technologies? The answer isn't found in chasing every innovation trend, it's in understanding which changes create genuine value and when to implement them across the product lifecycle.Irina Ramos brings a perspective earned through high-stakes execution. After leading the global technology transfer of AstraZeneca's COVID-19 vaccine, a project that compressed typical timelines while maintaining uncompromising quality standards, she's applying those lessons to the industry's next wave of challenges: phase-appropriate CMC strategy, the practical realities of AI integration, and building teams that bridge generational experience gaps in an era of rapid technological change.This conversation cuts through the noise. Irina discusses when continuous processing actually makes strategic sense (hint: it's not always the right answer), why AI in bioprocessing requires more human expertise rather than less, and the collaborative frameworks that enabled one of the fastest vaccine rollouts in history—lessons directly applicable to your current CMC challenges.Episode highlights:How the biotech community is constantly changing, and the importance of adaptability for future scientists (00:00)Navigating phase-appropriate CMC strategy: What to focus on in early clinical phases and which decisions set the foundation for compliance (02:36)Scenarios for switching from batch to continuous processing, including barriers and benefits for early-stage vs. established products (02:58)Lessons from leading AstraZeneca's COVID-19 vaccine technology transfer: Collaboration, rapid regulatory communication, and mission-driven teams (05:20)Adapting lessons from the pandemic for ongoing drug development—balancing speed and risk while maintaining quality (08:24)Realistic perspectives on integrating AI in bioprocessing: demystifying its applications, emphasizing human-critical oversight, and practical use cases in manufacturing (10:40)Key skills for scientists in a biotech world shaped by AI—why foundational understanding and strong mentorship matter (13:51)Bridging experience gaps: How to foster collaboration and creativity between new and established professionals in regulated environments (15:45)Final takeaway: Start small, remain mission-driven, and remember that one size does not fit all in continuous manufacturing (17:15)Whether you're evaluating process platform decisions for Phase I programs, building cross-functional teams for tech transfer, or determining which digital tools deserve investment beyond the buzzword, this episode provides decision frameworks grounded in real-world execution at global scale.Connect with Irina Ramos:LinkedIn: www.linkedin.com/in/irinaramosNext step:Need fast CMC guidance? New on-demand CMC advisory: Get 20 expert answers/month in 1 day + monthly strategy call. → Learn more: https://stan.store/SmartBiotech/p/ondemand-cmc-expertise-for-biotech-foundersBook a 20-minute call to help you get s
Alice Liu is the Research Lead at CoinMarketCap, leveraging CMC's data and collaborating with industry leaders to bring unique insight to millions of users. Her work covers market events, innovation analysis, and trending narratives across the entire crypto sector. Prior to joining CMC, Alice worked as an investment professional at WisdomeTree, Coutts, and J.P.Morgan. In this conversation, we discuss:- What happened on the 10/10 market crash - Current market sentiment - Liquidity is drying up - Are we in a bear market? - Privacy coins - The market is starved of narratives, hence why privacy took up - CMC20 Index - CMC Fear & Greed Index hit record low of 10 on Nov 22; has since rebounded to 15, consistent with past V-shape recoveries - Lista DAO - Watching onchain capital flow and whales - Total crypto market cap dropped below $3T — lowest since May, but signs show the worst is likely over CoinMarketCapX: @CoinMarketCapWebsite: coinmarketcap.comLinkedIn: CoinMarketCapAlice LiuX: @AliceCrypto3LinkedIn: Alice L.---------------------------------------------------------------------------------This episode is brought to you by PrimeXBT.PrimeXBT offers a robust trading system for both beginners and professional traders that demand highly reliable market data and performance. Traders of all experience levels can easily design and customize layouts and widgets to best fit their trading style. PrimeXBT is always offering innovative products and professional trading conditions to all customers. PrimeXBT is running an exclusive promotion for listeners of the podcast. After making your first deposit, 50% of that first deposit will be credited to your account as a bonus that can be used as additional collateral to open positions. Code: CRYPTONEWS50 This promotion is available for a month after activation. Click the link below: PrimeXBT x CRYPTONEWS50FollowApple PodcastsSpotifyAmazon MusicRSS FeedSee All
In this episode of Smart Energy Voices, we bring you a conversation from SED Forum Fall featuring Chris Pennington of Iron Mountain and Brett Thompson of CMC and moderated by Debra Chanil, Editorial & Research Director at Smart Energy Decisions. They explore a major shift underway in energy strategy, moving from a focus on procurement to optimizing how and when energy is used. As renewable generation grows, aligning consumption with clean energy availability is becoming increasingly important. Pennington shares how data centers are integrating on-site storage and hourly matching to enhance flexibility, while Thompson explains how CMC manages electric arc furnace operations and demand response participation to support grid reliability. Together, they highlight the growing need for flexible load strategies, stronger utility partnerships, and forward-looking planning in the ever-changing energy landscape. You will want to hear this episode if you are interested in… Why energy strategy is shifting from procurement to optimized usage (03:40) Changing grid dynamics and shifting peak pricing periods (07:39) Demand response and managing load peaks (14:20) Where energy customers should focus next (15:47) Policy and regulatory challenges (16:48) How data centers are affecting grid capacity and costs (18:18) The future of clean energy (20:24) For full episode show notes, click here. Connect with Chris Pennington On LinkedIn Chris Pennington is Director of Energy & Sustainability for Iron Mountain Data Centers. His responsibilities include the development of Iron Mountain's global sustainability program and identification of opportunities to innovate for a more sustainable digital future. He received the Green Power Leader of the Year award in 2021 from the Center for Resource Solutions and championed Iron Mountain's public commitment to 24/7 carbon free energy that same year. Chris actively participates in the Clean Energy Buyers Association as faculty for their energy buyer support programs, as well as Eurelectric's 24/7 carbon free energy hub. Connect With Smart Energy Decisions Smart Energy Decisions Follow us on LinkedIn Subscribe to Smart Energy Voices on Apple Podcasts, Google Podcasts, Android, Spotify, Stitcher, TuneIn Radio, aCast, PlayerFM, iHeart Radio If you're interested in participating in the next Smart Energy Decision Event, visit smartenergydecisions.com or email our Community Development team at attend@smartenergydecisions.com
Kathryn Golden didn't set out to be a scientist. In fact, she made her parents promise she wouldn't have to become one when she enrolled at a science-focused high school. But a chemistry class changed everything, setting her on a path from MIT's bioprocessing labs to senior leadership roles in Biotech and pharma. Now VP of Technical Operations at Ottimo Pharma and co-founder of Sunflower Therapeutics, Kathryn's career has been shaped by a relentless curiosity, a deep commitment to patient access, and a willingness to step into the unknown. She shares her journey from building perfusion bioreactors in grad school, to leading global CMC teams, to launching portable manufacturing units for biologics in the developing world. In this conversation, Kathryn reflects on lessons in leadership, mentorship, and integrity - from creating a calm, learning-focused culture to knowing when to walk away. She talks openly about imposter syndrome, what it really takes to transition into executive roles, and how entrepreneurship, like science, is best approached as an experiment.
Kaan Özaydın ve Akın Türkmen... Cleveland Browns'ta galibiyet ile başlayan Shedeur Sanders dönemi, Shedeur Sanders'a bile yenilen Las Vegas Raiders'ın hücum koçu Chip Kelly'i kovup üçüncü defa Greg Olson'ı hücumun başına geçirmesi, Brock Purdy'nin interception'larına rağmen kazanan San Francisco 49ers, CMC'nin muhteşem performansı... Ezeli rakibi ve son şampiyon Philadelphia Eagles'a ağır bir darbe indiren Dallas Cowboys, Lamar Jackson'ın zayıf performanslarına rağmen kazanan Ravens, Seahawks'ın seviye atlayan WR'ı Jaxon Smith-Njigba, Vikings'in bitmek bilmeyen J.J. McCarthy problemi, Buffalo Bills'te Josh Allen'ın şaşırtan kötü performansı ve dahası...
Big win in MNF! Vittoria importante per San Francisco contro dei Carolina Panthers con il vento in poppa.CMC come sempre monumentale in una prestazione degna del PrimeTime del lunedì notte!Nonostante gli errori e i cazzoti proibiti la corsa per la post season è ancora aperta!Per finire #askredegold con le domande egli ascoltatori!In diretta: Enzo, Davide e Gianluigi, con un contributo registrato di Stefano!ibile su tutte le piattaforme podcast e su YouTube con la Live Video
Today, I'm joined by Todd Meleney, co-founder & CEO of While on Earth. An athletic footwear and apparel brand for the modern wellness consumer, While on Earth prioritizes versatile "performance wellness" over single-sport specialization. In this episode, we discuss creating an underdog brand in a competitive market. We also cover: Christian McCaffrey's role as co-founder Defining "performance wellness" as a category Investing in grassroots community over paid marketing Subscribe to the podcast → insider.fitt.co/podcast Subscribe to our newsletter → insider.fitt.co/subscribe Follow us on LinkedIn → linkedin.com/company/fittinsider While On Earth's Website: www.whileonearth.co While On Earth's IG: https://www.instagram.com/whileonearth/ - The Fitt Insider Podcast is brought to you by EGYM. Visit EGYM.com to learn more about its smart fitness ecosystem for fitness and health facilities. Fitt Talent: https://talent.fitt.co/ Consulting: https://consulting.fitt.co/ Investments: https://capital.fitt.co/ Chapters: (00:00) Introduction (01:40) Todd's background and While on Earth overview (02:40) White space opportunity in performance footwear (04:25) Lessons from building NOBULL (05:15) Shifting consumer behavior toward holistic wellness (07:15) Defining "performance wellness" as a category (09:30) Product philosophy (12:00) Building vs. buying brand awareness (14:30) Grassroots community strategy over paid marketing (17:00) Retail strategy (19:30) Athlete partnerships (22:00) Christian McCaffrey as co-founder and investor (24:30) Product roadmap and innovation focus (27:00) Staying authentic while scaling (29:05) Running category launch in 2026 (30:15) CMC signature product line coming 2026 (32:45) Role of athletes in brand building (34:50) Conclusion
The San Francisco 49ers beat the Carolina Panthers 20-9 in Week 12, holding their ground in the NFC Playoff Race despite a rough night from Brock Purdy.Purdy threw 3 INTs (almost 5), but the 49ers defense bailed him out every time — led by Ji'Ayir Brown's two game-changing interceptions, including one in the end zone on 1st-and-Goal. Christian McCaffrey carried the offense with his 8th game of 50+ rushing and 50+ receiving yards, a TD, and nine touches on the opening 15-play drive. Jauan Jennings fought through three tackles for a tough TD, and Clelin Ferrell delivered a huge sack as the Panthers tried to rally.It wasn't pretty, but the 49ers controlled the clock, leaned on CMC, and made the clutch plays to escape with a must-have win.Can San Francisco keep climbing the NFC standings? Let's break it all downVisit Sports Spyder for up to date 49ers content: https://sportspyder.com/nfl/san-francisco-49ers/newsFollow us on Twitter @49ers_AccessFollow us on Instagram @49ers.AccessSeatGeek: “49ERSACCESS” for $20 off your first purchase!
The biotech industry operates under constant tension: we work with products that directly impact human lives, demanding rigorous controls and validation at every step. Yet standing still means falling behind. The question isn't whether to innovate, it's how to do it without compromising the quality and safety standards that define our industry.Irina Ramos has lived this paradox throughout her career. As a downstream processing leader who's guided CMC programs from early development through global regulatory filings, she helped orchestrate the worldwide transfer of AstraZeneca's COVID-19 vaccine—a masterclass in balancing speed, scale, and uncompromising quality standards. Now, she's championing a vision that sounds almost radical: lights-out biomanufacturing facilities where continuous processes run at steady state with minimal human intervention.In this conversation, Irina shares the unfiltered reality of building innovation cultures in conservative environments, the surprising drivers behind continuous processing adoption, and why the industry's careful nature isn't a barrier to transformation. It's the foundation for sustainable innovation.Discussion highlights:Why conservatism is vital in biotech—and how to balance it with innovation (00:00)The vision for "lights-out" manufacturing and if bioprocess facilities could run with minimal human intervention (02:50)Irina Ramos's career story and the lessons her "happy accidents" teach junior scientists (03:53)Mindset shifts: Transitioning from scientist to innovation leader in CMC development (06:29)Building an innovation culture in a conservative, highly regulated industry (08:07)Essential mindsets for scientists to thrive and innovate in biotech environments (11:22)Coordination strategies for effective communication across stakeholders, departments, and geographies (13:52)The misconceptions of continuous manufacturing and what actually drives its adoption (17:09)What's hot in continuous biomanufacturing: trends, global perspectives, and how real-time analytics can change process control (21:12)Guiding principles for choosing between hybrid or end-to-end continuous processes (23:46)Practical tips on implementing control strategies and real-time monitoring in manufacturing (25:01)If you're navigating the shift from batch to continuous processing, leading cross-functional innovation initiatives, or wondering how to advocate for new technologies without disrupting validated processes, this episode offers practical frameworks you can apply immediately.Connect with Irina Ramos:LinkedIn: www.linkedin.com/in/irinaramosNext step:Need fast CMC guidance? New on-demand CMC advisory: Get 20 expert answers/month in 1 day + monthly strategy call. → Learn more: https://stan.store/SmartBiotech/p/ondemand-cmc-expertise-for-biotech-foundersBook a 20-minute call to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/call
Onko Trumpin rauhansuunnitelmalla mahdollisuuksia toteutua ja mitä Nato-polun sulkeutuminen tarkoittaisi Ukrainalle? Studiossa vanhempi tutkija Iro Särkkä Ulkopoliittisesta instituutista ja johtava asiantuntija Jyrki Ruohomäki siviilikriisinhallinnan asiantuntijaorganisaatio CMC:stä. Ukrainan-toimittaja Justas Stasevskij raportoi Kiovasta. Uskaltavatko suomalaiset kuluttaa tänä jouluna? Kotitalouksien taloustilannetta avaavat Säästöpankin pääekonomisti Henna Mikkonen ja LähiTapiolan ekonomisti Hannu Nummiaro. Puhelimessa Kaupan liiton pääekonomisti Jaana Kurjenoja. Suomi kielsi venäläisten kiinteistökaupat viime kesänä turvallisuussyistä, mutta asuntoja käy yhä venäläisille kaupaksi. MOT selvitti asuntokauppojen taustoja. Studiossa toimittaja Jyri Hänninen. Juontajana Mari Sarolahti. Tuottajina Rasmus Montonen ja Anna-Maria Haarala. Toimittajina Petra Nykänen ja Satu Heikkilä.
On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan reflect on the blockbuster trade that brought Christian McCaffrey to San Francisco ahead of Monday night's matchup against his former team. Additionally, Matt and Jennifer discuss how a healthy 49ers offense will improve their run game. Matt then sits down with defensive back Deommodore Lenoir to discuss his growth as a leader and team captain of the 49ers' defense.--(1:53) Matt, JLC reflect on 49ers' trade that brought Christian McCaffrey to San Francisco(6:12) Matt discusses how CMC has blossomed into face of the 49ers' offense and playing at an all-time level(12:56) Matt, JLC discuss how a healthy 49ers offense will improve CMC's running game(17:08) Matt, JLC debate if matchup vs. Panthers is a must-win game(25:00) Deommodore Lenoir discusses what it means to him to be a captain on the 49ers, and finding his voice, role as a leader(29:05) Lenoir talks how Richard Sherman took notice of his potential as a young player(37:55) Matt, JLC discuss if Lenoir get enough attention for his playmaking(42:20) Matt wants to see rookie LB Nick Martin on the field as a pass rusher Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Dirty Work Hour 1: 49ers/Panthers preview, Matchups vs Rico Dowdle, T-Mac and Bryce Young, CMC vs his old teamSee omnystudio.com/listener for privacy information.
In the third hour, Mac & Bone turn their attention to the 49ers, to talk about facing CMC for the first time since the trade, they discuss the problems he'll cause, and if this is a revenge game for CMC, they open the phones to hear from Hornets fans on the LaMelo trade rumors, & they preview the Duke/UNC football game See omnystudio.com/listener for privacy information.
Dirty Work Hour 1: 49ers/Panthers preview, Matchups vs Rico Dowdle, T-Mac and Bryce Young, CMC vs his old teamSee omnystudio.com/listener for privacy information.
In the 2nd hour of the show, Kyle and Smoke look at this being the first time that CMC has played his former team since being traded in 2022, and if fans still have a problem with the perceived passive-aggressive nature of his final year or so in Carolina, and Corey Miller dropped by to weigh in on the struggles of the Gamecocks See omnystudio.com/listener for privacy information.
What if you could analyze every metabolite, glycan variant, and unknown impurity in your bioprocess sample—not just the targets you're looking for, but everything that's actually there? Cryogenic infrared ion spectroscopy combined (CIRIS) with AI-powered analysis transforms untargeted screening from aspiration to reality.This episode moves from fundamental principles to practical applications. While Part 1 established how CIRIS overcomes mass spectrometry's structural limitations, Part 2 reveals what becomes possible when you can definitively identify complex mixtures: better mAb characterization, earlier disease detection, and process decisions based on complete data rather than educated guesses.Professor Tom Rizzo returns to discuss Isospec Analytics' path from laboratory innovation to commercial service platform. His transition from academic leadership at EPFL to biotech entrepreneurship offers insights for any scientist considering whether breakthrough research deserves a startup—and what that journey actually requires.For bioprocess scientists drowning in unidentified peaks, struggling with glycan heterogeneity, or making critical manufacturing decisions with incomplete analytical data, this conversation demonstrates how next-generation analytics powered by quantum chemistry and machine learning can illuminate what's been hidden in your samples all along.Episode Highlights:Why targeted metabolomics creates a "streetlight effect"—and how untargeted CIRIS analysis reveals the complete molecular landscape (00:00)Isomer-specific glycan characterization for mAbs: distinguishing structural variants that impact efficacy and immunogenicity (03:17)Advanced disease detection and biomarker discovery: identifying diagnostic signatures in complex biological matrices (05:21)AI meets quantum chemistry: automated spectral library building and machine learning algorithms that accelerate molecule identification from hours to seconds (06:05)From data generation to decision-making: how comprehensive analytics and AI transform bioprocess development workflows (09:23)Isospec's commercial roadmap: service platform for comprehensive sample analysis and projected timeline for benchtop instrumentation (10:09)Academic to entrepreneur: Tom Rizzo's perspective on leaving tenure for a startup, with practical advice for scientists evaluating the leap (12:05)Personal motivation behind early diagnostics: cancer and leukemia experiences that drive Isospec's clinical applications (14:11)Technical deep dive: messenger tagging methodology and achieving single-ion infrared detection sensitivity (15:41)The transformative capability: adding a structural dimension to mass spec data that eliminates ambiguity in complex mixture analysis (17:55)Mass spectrometry tells you what masses are present. Cryogenic infrared ion spectroscopy tells you what molecules they actually are. When coupled with AI-powered analysis, this combination enables truly comprehensive characterization—from process impurity identification to critical quality attribute assessment to early disease biomarker discovery.If you're making bioprocess decisions with incomplete analytical information, managing glycan complexity in biologics development, or exploring how emerging analytical technologies could solve your toughest characterization challenges, this episode provides both the technical foundation and the commercial pathway forward.
Welcome to the Paint The Medical Picture Podcast, created and hosted by Sonal Patel, CPMA, CPC, CMC, ICD-10-CM.Thanks to all of you for making this a Top 15 Medical Billing & Coding Podcast for 5 Years on Feedspot. Sonal's 16th Season starts up and Episode 12 features a Newsworthy update on RAC audits for 2025.Sonal's Trusty Tip and compliance recommendations focus on specific RAC audits for 2025.Spark inspires us all to reflect on resilience based on the inspirational words of Isabel Allende.Paint The Medical Picture Podcast now on:Spotify: https://open.spotify.com/show/6hcJAHHrqNLo9UmKtqRP3XApple Podcasts: https://podcasts.apple.com/us/podcast/paint-the-medical-picture-podcast/id1530442177Amazon Music: https://music.amazon.com/podcasts/bc6146d7-3d30-4b73-ae7f-d77d6046fe6a/paint-the-medical-picture-podcastFind Paint The Medical Picture Podcast on YouTube: https://www.youtube.com/channel/UCzNUxmYdIU_U8I5hP91Kk7AFind Sonal on LinkedIn: https://www.linkedin.com/in/sonapate/And checkout the website: https://paintthemedicalpicturepodcast.com/If you'd like to be a sponsor of the Paint The Medical Picture Podcast series, please contact Sonal directly for pricing: PaintTheMedicalPicturePodcast@gmail.com
Children's mental health isn't just a family issue—it's a workplace issue. When kids struggle, parents and caregivers face missed work and mounting stress, creating ripple effects across their lives. This week we explore the link between children's mental health and workplace performance, and the roles Central Ohio employers, healthcare leaders, and advocates are playing in breaking the cycle of stress for families. Featuring: Anna Ankenbauer, Senior Director, Global Giving, Engagement, Learning & Development, Abercrombie & Fitch Co. Nina Day, Community Mental Health Advocate. Dr. Ariana Hoet, Executive Director, The Kids Mental Health Foundation. The host is Cierra Johnson, Anchor & Reporter, NBC4. This forum was sponsored by Cardinal Health. The presenting sponsor of the CMC livestream was The Center for Human Kindness at the Columbus Foundation. CMC's livestream partner was The Columbus Dispatch. This forum was also supported by Downtown Columbus, Inc. and The National Veterans Memorial and Museum. If you're ready to keep exploring this week's forum topic, our partners at The Columbus Metropolitan Library recommend reading Finding Time: The Economics of Work-Life Conflict, by Heather Boushey. This forum was recorded before a live audience at The National Veterans Memorial and Museum in Columbus, Ohio on November 19, 2025.
Damon Bruce Plus: Warriors, 49ers, Giants, A’s Bay Area Sports Talk
1:55: The opening statement of Christian McCaffrey's MVP case:11:24: The 49ers win 75 PERCENT of the time with McCaffrey in the lineup12:26: Rant: How does Kyle Shanahan still not understand that the 49ers are “totally f—ked” without CMC? — Get him off the field in blowouts18:10: McCaffrey is even more valuable than Kyle21:13: Somehow, Shedeur Sanders' nightmare debut got even worse after the game37:21: Draymond Green's big mistake after the Angel Reese chant:47:51: Today in history: Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
What if you could identify every structural variant in your biologics—without ambiguity, without massive sample requirements, and without the guesswork that plagues traditional mass spectrometry? Cryogenic infrared ion spectroscopy (CIRIS) makes it possible, transforming molecular characterization from frustrating puzzle to precise science.Today's guest, Professor Tom Rizzo, bridges the gap between academic innovation and industrial application. As former Dean of the School of Basic Sciences at EPFL in Lausanne and now Chief Scientific Officer at Isospec Analytics, Tom has spent over two decades developing analytical techniques that solve problems conventional methods can't touch.His journey from a childhood fascination sparked by chemistry demonstrations at the 1964 New York World's Fair to pioneering a breakthrough technology reveals both the persistence required for true innovation and the pathway from laboratory curiosity to commercial reality. For bioprocess scientists struggling with glycan characterization, isomer identification, or any structural puzzle where mass spec alone falls short, this conversation offers both validation and solutions.Episode Highlights:The fundamental limitations of current biomolecular analysis methods and why innovation is critical (02:51)From World's Fair chemistry demos to laser spectroscopy: Tom Rizzo's path to analytical innovation (03:31)The two-decade quest to combine mass spectrometry sensitivity with laser spectroscopy precision—and the machine that finally made it work (04:26)Why Tom transitioned from academic leadership to Isospec Analytics: bringing lab techniques to production environments (09:17)CIRIS fundamentals: how cooling ions to 10 Kelvin unlocks molecular fingerprints that room-temperature methods miss (11:14)CIRIS advantages for biologics: single-ion sensitivity, isomer discrimination, and unique molecular "fingerprints" for definitive identification (14:25)Integrating CIRIS into existing bioprocess workflows: LC-MS compatibility and the path to commercial instrumentation (17:29)Hard-won lessons from translating academic breakthroughs into industrial tools (17:43)When mass spectrometry hits its limits—distinguishing isomers, characterizing glycans, identifying unknowns in complex mixtures—cryogenic infrared ion spectroscopy provides the structural resolution you need. This isn't incremental improvement; it's a fundamental expansion of what's analytically possible.If you're facing molecular identification challenges that conventional methods can't solve, or if you're curious how next-generation analytical techniques will transform bioprocess development, this episode delivers actionable insights from a scientist who's lived both the innovation and implementation journey.Connect with Tom Rizzo:LinkedIn: www.linkedin.com/in/thomas-rizzo-4a0a6314/Contact email: tom@isospec.chIsospec Analytics website: www.isospecanalytics.comNext step:Book a 20-minute call to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/call
Brock Purdy's return sparked the 49ers' offense, it also brought a much needed divisional win in a blowout against the Cardinals. Purdy threw for three touchdowns on Sunday, two of which went to a favorite target in tight end George Kittle and the other went to offensive fulcrum Christian McCaffrey, who leads the NFL in scrimmage yards this season through Week 11. Skyy Moore set the tone, returning the opening kickoff 98 yards to the 1-yard line, setting up a McCaffrey 1-yard touchdown run. San Francisco maintained control throughout the game, one in which Arizona did itself no favors accumulating a franchise-record 17 penalties. San Francisco did not escape Arizona unscathed though, as kicker Eddy Piñeiro suffered a hamstring injury in the third quarter that could force the team to bring in a new kicker. On this episode of '49ers Talk,' co-hosts Matt Maiocco and Jennifer Lee Chan break down San Francisco's outstanding performance against the Cardinals Sunday at State Farm Stadium. Matt and Jennifer discuss the impact of Purdy's return on the 49ers' offense during a crucial stretch, Kittle and CMC's dominance, and how injuries to both Piñeiro and linebacker Tatum Bethune might affect the team ahead of Monday's showdown with the Carolina Panthers.--(0:00) 49ers did what they had to do to get win vs. Cardinals(3:00) Will the 49ers have to add a kicker because of Eddy Piñeiro's injury?(4:00) Brock Purdy's return dispels any QB controversy from media(12:00) Can CMC achieve 1,000-1,000 season?(14:00) This is the healthiest the 49ers have been on offense all season(17:30) The 49ers' defense forced three takeaways(25:00) What type of team are the 49ers? Can they bring this type of performance on MNF?(28:00) Robert Saleh will really have to earn his money down the stretch this season(30:00) Looking ahead, the 49ers need beat NFC playoff contenders Carolina, Chicago Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
The San Francisco 49ers dominated the Cardinals 41-22 in Week 11 behind a huge day from Brock Purdy, Christian McCaffrey, and George Kittle. Purdy returned to the lineup with 3 touchdowns, including two to Kittle and one to CMC, as Kyle Shanahan kept the offense aggressive all game long.Special teams set the tone early with Skyy Moore's 98-yard kickoff return, leading to a quick McCaffrey TD. CMC finished with 3 total touchdowns, 121 scrimmage yards, and his first 20+ yard run of the season. Kittle added 6 catches, 67 yards, and 2 scores in another dominant outing.The 49ers defense delivered 3 takeaways (INTs by Lenoir and Mustapha, a goal-line FF by Upton Stout) and made key stops despite coverage issues and a quiet pass rush. Arizona hurt themselves with 17 penalties for 130 yards, while San Francisco committed just one.Visit Sports Spyder for up to date 49ers content: https://sportspyder.com/nfl/san-francisco-49ers/newsFollow us on Twitter @49ers_AccessFollow us on Instagram @49ers.AccessSeatGeek: “49ERSACCESS” for $20 off your first purchase!#49ers #Cardinals #NFLWeek11 #SanFrancisco49ers #ArizonaCardinals
HOST: Mark Longo, The Options Insider CO-HOST: Mike Tosaw, St. Charles Wealth Management CO-HOST: Andrew Giovinazzi, The Option Pit In this episode, the panel discusses the current state of the options market. They also look at unusual options activity in CMC and QGEN. Uncle Mike Tosaw provides a Strategy Block focusing on the importance of responsible options trading and knowing when to exit a position. Market conditions, including significant whipsaw action in the S&P 500 and notable upcoming earnings reports from major retailers like Home Depot, Lowe's, and Target, are analyzed. The episode concludes with insights on what the hosts are watching in the market for the upcoming week.
Week 11 NFL DFS was a rollercoaster of chalk. Did Davis, Sammy, and Nate find a way to the top?
HOST: Mark Longo, The Options Insider CO-HOST: Mike Tosaw, St. Charles Wealth Management CO-HOST: Andrew Giovinazzi, The Option Pit In this episode, the panel discusses the current state of the options market. They also look at unusual options activity in CMC and QGEN. Uncle Mike Tosaw provides a Strategy Block focusing on the importance of responsible options trading and knowing when to exit a position. Market conditions, including significant whipsaw action in the S&P 500 and notable upcoming earnings reports from major retailers like Home Depot, Lowe's, and Target, are analyzed. The episode concludes with insights on what the hosts are watching in the market for the upcoming week.
JMToWin from One Week Season walks us through the Week 11 DFS slate from a GPP perspective, shares his top plays at each position, and then builds a DraftKings lineup using some of his favorite building blocks. In the second half, Youdacao from Run The Sims join to discuss sneaky stacks for Week 11 tournaments and input volatility.
In this episode of Molecule to Market, your host Raman Sehgal discusses the pharmaceutical and biotechnology supply chain with Jean-François Brepson, Chief Executive Officer at PathoQuest. The conversation covers: Navigating 20 years of global leadership roles at Ipsen before moving from the corporate world into an investor-led entrepreneurial adventure The tough decision to refocus PathoQuest from diagnostics into a pure play CRO and pharma services business How a major strategic partnership transformed the company's trajectory and why Jean sees partnerships as a competitive weapon Riding the tailwind of the FDA's move away from animal testing and offering something game-changing in the CMC and GMP space The opportunities ahead for CROs and CDMOs in helping unlock the next wave of innovation Jean-François Brepson is a dedicated leader with deep experience in biotechnology and pharmaceuticals. Since becoming CEO of PathoQuest in 2015, he has built the company into a leading global CRO specializing in quality control of biological drugs using Next Generation Sequencing (NGS). Over his career, he has advanced innovative technologies and solutions that bridge scientific progress with real-world application. Prior to joining PathoQuest, Jean was Senior Vice President at Ipsen, where he led the global GI-Oncology and Endocrinology franchise. Molecule to Market is sponsored by Bora Pharma, Charles River, and Lead Candidate. Please subscribe, tell your industry colleagues, and help us celebrate the value of the global life science outsourcing space. We'd also appreciate a positive rating!
Carbon neutrality goals are everywhere in biopharma. But how do you actually measure and reduce your true environmental impact when data gaps and baseline differences make comparisons so tough?In this episode, David Brühlmann talks with Niklas Jungnelius, Cytiva's expert in process modeling and sustainability, who's spent years uncovering what really drives emissions and how small process tweaks can deliver big results.Niklas goes beyond the numbers, challenging assumptions and showing how sustainability becomes a strategic, data-driven advantage. From real-world cases at Cytiva, he explains why recycling plastics may not move the needle and why the real gains often lie in hotspots like cleanroom energy use and raw material choices.Here's why this episode will make you rethink your next facility upgrade:Understanding life cycle assessment and the key damage categories in environmental sustainability, including carbon emissions, water usage, and resource depletion. (00:00)The challenge of defining carbon emissions baselines and why it's harder, and often more expensive, to achieve deep reductions if your operations already use clean energy sources. (03:06)Why the focus on recycling single-use plastics may not be the most effective route for lowering emissions, and what truly drives carbon footprint in bioprocessing. (05:54)The impact of production scale, consumables, and obscure chemicals on the overall environmental impact and how these surprises can shift sustainability strategies. (06:20)Practical advice for scientists and engineers: How to start monitoring and modeling environmental impact in process development and manufacturing. (08:00)The importance of involving manufacturing perspectives early in process development, and choosing the right level of detail and ambition for process modeling. (08:18)There's no one-size-fits-all in manufacturing technology—whether fed-batch, continuous, or hybrid and decisions must fit each organization's needs, resources, and ambitions. (10:13)Industry trends that could transform the field, from intensified fed-batch production to future technologies like cell-free expression systems. (11:22)Where to connect with Niklas for further questions or collaboration. (14:03]Whether you're an early-stage startup, a strategic advisor, or on the front lines of bioprocess development, this episode invites you to rethink your sustainability strategy and modeling approach. Check out the below links to connect with Niklas Jungnelius and additional resources.Connect with Niklas Jungnelius:LinkedIn: www.linkedin.com/in/niklas-jungneliusCytiva website: www.cytivalifesciences.com/en/usNext step:Book a 20-minute call to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/call
Welcome to the Paint The Medical Picture Podcast, created and hosted by Sonal Patel, CPMA, CPC, CMC, ICD-10-CM.Thanks to all of you for making this a Top 15 Medical Billing & Coding Podcast for 5 Years on Feedspot. Sonal's 16th Season starts up and Episode 11 features a Newsworthy update on the OIG Work Plan for October 2025.Sonal's Trusty Tip and compliance recommendations focus on another claims processing update from Medicare.Spark inspires us all to reflect on resilience based on the inspirational words of Ernest Hemingway.Paint The Medical Picture Podcast now on:Spotify: https://open.spotify.com/show/6hcJAHHrqNLo9UmKtqRP3XApple Podcasts: https://podcasts.apple.com/us/podcast/paint-the-medical-picture-podcast/id1530442177Amazon Music: https://music.amazon.com/podcasts/bc6146d7-3d30-4b73-ae7f-d77d6046fe6a/paint-the-medical-picture-podcastFind Paint The Medical Picture Podcast on YouTube: https://www.youtube.com/channel/UCzNUxmYdIU_U8I5hP91Kk7AFind Sonal on LinkedIn: https://www.linkedin.com/in/sonapate/And checkout the website: https://paintthemedicalpicturepodcast.com/If you'd like to be a sponsor of the Paint The Medical Picture Podcast series, please contact Sonal directly for pricing: PaintTheMedicalPicturePodcast@gmail.com
Small businesses are the backbone of Central Ohio's economy—creating jobs, fueling innovation, and shaping the future of our communities. Despite inflation, labor shortages, and tariffs, many small business owners report feeling optimistic about the future. This week we explore why. Featuring: Stuart Hoffman, Senior Economic Advisor, PNC Financial Services Group Tim Kehoe, Director, Economic and Community Development Institute's Veterans Business Outreach Center of Ohio Ariana Ulloa-Olavarrieta, Small Business Coordinator, City of Columbus Walter Eguez, Founder, Tortilla Street Food The host is Susan Post, Digital Editor, Columbus Business First. This forum was sponsored by PNC. The presenting sponsor of the CMC livestream was The Center for Human Kindness at the Columbus Foundation. CMC's livestream partner was The Columbus Dispatch. This forum was also supported by Downtown Columbus, Inc. and The National Veterans Memorial and Museum. If you're ready to keep exploring this week's forum topic, our friends at the Columbus Metropolitan Library recommend reading The New Builders: Face to Face with the True Future of Business by Seth Levine. This forum was recorded before a live audience at The National Veterans Memorial and Museum in Columbus, Ohio on November 12, 2025.
Your Manufacturing Decisions Are Costing You More Than You ThinkEvery bioreactor decision. Every scale-up choice. Every facility investment. They're all silently writing checks your process might not be able to cash.The difference between a profitable biologics program and one that bleeds capital? Process economic modeling, the analytical framework that reveals exactly where your money goes and why.In this episode of the Smart Biotech Scientist Podcast, David Brühlmann talks with Niklas Jungnelius, Process Modeling Leader at Cytiva, who has spent 25+ years decoding the economics of biologics manufacturing for biotech companies navigating billion-dollar decisions.Niklas reveals the hidden cost drivers most teams miss, the surprising economics behind fed-batch vs. continuous processing, and why your facility choice at intermediate scale could make or break your business case.Episode Highlights:What process economic modeling is and how it differs from mechanistic modeling (06:40)Main cost drivers in biologics and biosimilars manufacturing, and their direct and indirect impacts on patient pricing (09:21)The role of manufacturing scale and productivity in driving down costs, and how facility type (stainless steel vs single-use) affects labor, flexibility, and investment (11:51)Trade-offs between single-use and stainless steel facilities at intermediate production scales (15:07)Key differences in cost and efficiency between fed-batch and fully continuous manufacturing, including productivity limitations and capital/expenditure implications (16:20)The impact of resin lifetime and under-utilization on clinical manufacturing costs (19:51)Hidden or less quantifiable costs such as facility flexibility, excess capacity, safety margins, and the importance of realistic assumptions in economic modeling (20:20)This is a grounded discussion with practical takeaways for biotech scientists seeking clarity in the complex terrain of process economics. Part two of this conversation will focus on sustainability modeling and the latest technologies reshaping bioprocessing economics.Ready to see how process modeling could transform your approach and protect your bottom line? Listen to the episode and rethink your next investment.Connect with Niklas Jungnelius:LinkedIn: www.linkedin.com/in/niklas-jungneliusCytiva website: www.cytivalifesciences.com/en/usNext step:Book a 20-minute call to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/call
Damon Bruce Plus: Warriors, 49ers, Giants, A’s Bay Area Sports Talk
0:15: That was awful from the jump — “Kyle is playing with fire”, get the starters out of there5:45: Unfortunately for the 49ers, the Rams and Seahawks are both very, very good7:40: As bad as this looks, the 49ers are about to go 4-012:22: Stick with Mac Jones (through the bye week) — he's given the 49ers no reason to take him off the field14:22: Why do 49ers keep getting hurt in PRACTICE?15:29: Rant: “I'm over Jauan Jennings”16:21: A deep dive on the draft failures of Shanahan and Lynch:24:36: Speaking of young guys who don't matter — look at the Warriors:26:18: RIP Lenny Wilkens and Paul Tagliabue29:56: The sports gambling “locomotive” is about to hit the industry: Hello, Guardians pitchers34:22: Today in history: Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
We just lowered the prices on all of our packages, and promo code 'GURU' gets you an extra 15% off of our already discounted 50% off price tag. https://www.fantasypoints.com/plans#/ Get ready for a wild ride! John Hansen and Brian Drake bring unmatched energy as they tear through every game from NFL Week 10 on the Fantasy Points Podcast. From Jonathan Taylor's monster performance and Tez Johnson's breakout to Trey McBride's domination, the duo leaves no fantasy storyline untouched. Expect bold takes, sharp betting advice, and unfiltered banter as they spotlight key trends from Lamar Jackson's continued tear, CMC's revenge game, and Detroit's rise. Packed with insider stats, waiver wire gems, and league-winning strategy, this is fantasy football analysis at full throttle. Tune in and get ready to CRUSH Week 11. Where to find us: http//twitter.com/Fantasy_Guru http://twitter.com/DrakeFantasy Podcast Transcription Here: https://podsqueeze.com/embedded/transcript/7WCRFizJRc3MAfGQZKazRw Join our Discord here: https://www.fantasypoints.com/media/discord#/ Subscribe to Fantasy Points for FREE - https://www.fantasypoints.com/plans#/ Listen to the podcast here: https://www.fantasypoints.com/media/podcasts #FantasyFootball #FantasyFootball2025 #NFLWeek6 #FantasyPointsPodcast #FantasyFootballAnalysis #NFLRecap #FantasyFootballAdvice #FantasyPoints #NFL2025 Learn more about your ad choices. Visit megaphone.fm/adchoices
Todd and Jerry talk about the big win in NY against the Giants, but at what cost...they lose Mykel Williams to a torn ACL.CMC continues to carry the team. Mac Jones looks good.BUT, why was there no help at the trade deadline? Major questions there.A spin around the whole NFL and Todd gives another reason he dislikes Halloween.
Cell and gene therapies are transforming modern medicine, but their path to market is fast and complex. They often jump from small trials to global launch at record speed, putting pressure on analytics, supply chains, and partnerships. Success depends on making smart choices about what to build in-house and what to entrust to expert partners.Daniel Galbraith knows these challenges intimately. With decades of hands-on experience and as Chief Scientific Officer at Solvias, Daniel has witnessed firsthand the seismic shifts in analytical development for advanced therapies. He's been on every side of the table: troubleshooting manufacturing snags, scaling up from a single batch to hundreds per month, and guiding companies as they choose between in-house development and relying on a CRO's muscle.In this episode:How evolving cell and gene therapy timelines are driving the need for true CRO-drug developer partnerships (00:00)The unique challenges of scaling CMC analytics from early trials to global commercialization (02:51)Key pitfalls to avoid when outsourcing to CROs—especially around communication, scheduling, and troubleshooting (06:26)Deciding whether to build capabilities in-house or outsource to a CRO, and how to find the right balance for your team (08:41)The critical importance of strong project management for juggling relationships between developer, CRO, and CDMO (09:51)Daniel's perspective on the future of combination therapies and what the analytical landscape will demand of CROs (13:33)Practical advice for building transparent, open CRO partnerships that support your goals (15:21)Facing scale-up challenges or a first CGT launch? This conversation shares practical strategies to advance therapies efficiently.Tune in for actionable insights on CMC, outsourcing, and analytical development.Connect with Daniel Galbraith:LinkedIn: www.linkedin.com/in/daniel-galbraith-26a6138Solvias website: www.solvias.comEmail: daniel.galbraith@solvias.comNext step:Book a 20-minute call to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/callPreparing for your IND? Grab our Startup Founder CMC Dashboard in Notion to help you track tasks, timelines, and risks in one place at https://stan.store/SmartBiotech/p/discovertoind-cmc-dashboard-for-startup-founders
Welcome to the Paint The Medical Picture Podcast, created and hosted by Sonal Patel, CPMA, CPC, CMC, ICD-10-CM.Thanks to all of you for making this a Top 15 Podcast for 5 Years: https://blog.feedspot.com/medical_billing_and_coding_podcasts/Sonal's 16th Season starts up and Episode 10 features a Newsworthy spotlight on November as Lung Cancer Awareness Month.Sonal's Trusty Tip and compliance recommendations focus on telehealth updates made in the CY 2026 Medicare Physician Fee Schedule Final Rule. Spark inspires us all to reflect on resilience based on the inspirational words of Margaret Thatcher.Lung Cancer Awareness Month:American Lung Association® Website: https://www.lung.org/lung-force/about-lung-force/featured-campaigns/lung-cancer-awareness-monthPaint The Medical Picture Podcast now on:Spotify: https://open.spotify.com/show/6hcJAHHrqNLo9UmKtqRP3XApple Podcasts: https://podcasts.apple.com/us/podcast/paint-the-medical-picture-podcast/id1530442177Amazon Music: https://music.amazon.com/podcasts/bc6146d7-3d30-4b73-ae7f-d77d6046fe6a/paint-the-medical-picture-podcastFind Paint The Medical Picture Podcast on YouTube: https://www.youtube.com/channel/UCzNUxmYdIU_U8I5hP91Kk7AFind Sonal on LinkedIn: https://www.linkedin.com/in/sonapate/And checkout the website: https://paintthemedicalpicturepodcast.com/If you'd like to be a sponsor of the Paint The Medical Picture Podcast series, please contact Sonal directly for pricing: PaintTheMedicalPicturePodcast@gmail.com
Unlock your Week 10 fantasy football edge with 12 Must-Know Fantasy Football Stats for NFL Week 10! Keith Flemming and Kacey Kasem break down 12 must-know stats and trends to help you crush your lineup and waiver wire decisions. Whether you're rolling after a big Week 9 or battling back from a tough week, these insights give you the upper hand in your fantasy football leagues.(00:00) Intro (01:17) Brock Bowers(03:46) CMC(05:32) Drake London(07:16) Kyle Monangai(09:06) Rico Dowdle (11:14) Patriots Elite Run D(12:08) Bengals Pathetic Defense(13:47) Chargers Lose Joe Alt(15:38) Rasheed Shaheed to Seahawks!(18:20) This Bills Team Built For Playoffs?(23:40) Giants Backfield Subscribe for expert fantasy football advice, rankings, waiver wire pickups, and trade tips all season long! Like, comment, and hit the notification bell so you never miss our latest insights.
Finding an analytical CRO that's truly invested in your success, not just processing samples, makes all the difference in CMC development. In this episode, host David Brühlmann talks with Daniel Galbraith, Chief Scientific Officer at Solvias, about the essential questions and mindset that lead to breakthrough CRO partnerships.With nearly three decades in analytical development, spanning monoclonal antibodies, biosimilars, and cell and gene therapies, Daniel reveals what separates CROs who become true partners from those who just run methods. His insights can save your program months of delays and costly missteps.Key Topics Discussed:Why cell and gene therapies face unique challenges compared to the progression seen with monoclonal antibodies (03:04)Daniel's career path: from entering biotech in 1996 to CSO at Solvias, and the rapid evolution of the industry (05:00)The analytical hurdles in characterizing cell-based products and how their inherent variability impacts development (09:46)Approaches to analytical method requirements for autologous cell therapies, and how data is gathered iteratively in these cases (13:02)The biggest obstacles to scaling up cell and gene therapies, and why innovative cell manipulation technologies are needed (16:06)Current trends in therapeutic modalities: why antibody-drug conjugates stand out, and whether mRNA therapies are losing momentum (18:37)Practical advice on choosing an analytical CRO as a strategic partner - what to look for, what questions to ask, and why enthusiasm and standardization matter (21:55)Wondering how to streamline your own analytical strategy, or navigate the parallel universe of cell and gene therapy development? Dig into this episode for Daniel's insider perspective. Then consider how the right analytical partnership could accelerate your path to clinic.Connect with Daniel Galbraith:LinkedIn: www.linkedin.com/in/daniel-galbraith-26a6138Solvias website: www.solvias.comEmail: daniel.galbraith@solvias.comNext step:Book a 20-minute call to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/callPreparing for your IND? Grab our Startup Founder CMC Dashboard in Notion to help you track tasks, timelines, and risks in one place at https://stan.store/SmartBiotech/p/discovertoind-cmc-dashboard-for-startup-founders
Steiny & Guru chat with NFL Audacy Insider Ross Tucker about the 49ers 6-3 start, what a move means for the rest of their season, a legit threat to the NFC West, and why no other player has more of Ross' respect than CMC.
(0:00) Vikings upset Lions(10:00) Bears come back, take down Bengals(17:00) Packers fall to Panthers(22:00) Seahawks dominate Commanders(30:00) Patriots edge out Falcons(35:00) Stafford shines over Saints(40:00) CMC too much for Giants(42:00) Broncos take down Texans(45:00) Chargers rally to defeat Titans(48:00) Jags def. Raiders in OT; K Cam Little makes NFL history(51:00) Arrow Up / Arrow Down: Week 9 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
JMToWin from One Week Season walks us through the Week 9 DFS slate from a GPP perspective, shares his top plays at each position, and then builds a DraftKings lineup using some of his favorite building blocks. In the second half, Youdacao from Run The Sims join to discuss sneaky stacks for Week 9 tournaments and input volatility.
Welcome to the Paint The Medical Picture Podcast, created and hosted by Sonal Patel, BA, CPMA, CPC, CMC, ICD-10-CM.Thanks to all of you for making this a Top 15 Podcast for 5 Years: https://blog.feedspot.com/medical_billing_and_coding_podcasts/Sonal's 16th Season starts up and Episode 9 features Newsworthy updates on the month's fraud, waste, and abuse cases. Sonal's Trusty Tip and compliance recommendations focus on diagnosis coding for family history of breast cancer.Spark inspires us all to reflect on resilience based on the inspirational words of Maya Angelou.Paint The Medical Picture Podcast now on:Spotify: https://open.spotify.com/show/6hcJAHHrqNLo9UmKtqRP3XApple Podcasts: https://podcasts.apple.com/us/podcast/paint-the-medical-picture-podcast/id1530442177Amazon Music: https://music.amazon.com/podcasts/bc6146d7-3d30-4b73-ae7f-d77d6046fe6a/paint-the-medical-picture-podcastFind Paint The Medical Picture Podcast on YouTube: https://www.youtube.com/channel/UCzNUxmYdIU_U8I5hP91Kk7AFind Sonal on LinkedIn: https://www.linkedin.com/in/sonapate/And checkout the website: https://paintthemedicalpicturepodcast.com/If you'd like to be a sponsor of the Paint The Medical Picture Podcast series, please contact Sonal directly for pricing: PaintTheMedicalPicturePodcast@gmail.com
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