Podcasts about CMC

Dirty Work Hour 3: The Boys bring you another flaming edition of the Sound Soiree featuring: CMC, Tiffany Haddish, & an enraged Knicks fan, & they also sit down with legendary sportscaster Kenny Mayne to talk Super Bowl.See omnystudio.com/listener for privacy information.

2:55: No one on Media Row actually seems to be talking about the Super Bowl 10:12: The death of journalism is the plan: 16:11: Jeffery Simmons joins the show: 34:01: Ike joins the show: 37:41: Ed McCaffrey 58:53: Today in history: Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Dirty Work Hour 1: Legendary broadcaster, Kevin Harlan joins the boys to break down the Super Bowl, the Warriors huge win over the Suns, & the crew also break down NFL Awards Night & 49ers running backs getting snubbed & honored (Roger Craig, CMC, Frank Gore)See omnystudio.com/listener for privacy information.

Hour 1: Papa & Silver discuss Roger Craig making the Hall of Fame, and touch on CMC winning the comeback player of the year award. Chris Berman joins the show to share his favorite Super Bowl moments. Matt Maiocco joins the show to discuss why Roger Craig deserves to be in the Hall of Fame and why he finally got the nod. See omnystudio.com/listener for privacy information.

Star running back Christian McCaffrey joined "49ers Talk" host Matt Maiocco on Day 3 of Super Bowl Radio Row at Moscone Center to share his pride in receiving the NFL's 15th annual Salute to Service Award and offer his support to Hall of Fame candidate Roger Craig. Next up was another 49ers legend, Terrell Owens, who stopped by to relive his iconic Sharpie celebration and offer his critique on the Hall of Fame selection process. San Francisco rookie CJ West popped in to discuss areas he can improve in his sophomore season, and former wily quarterback for the Red and Gold, Jeff Garica, shared how he believes current starter Brock Purdy's "underdog" mentality keeps him competitive. Finally, former defensive back Logan Ryan details what traits Upton Stout possesses to be the 49ers' next great nickel corner.--(7:00) CMC honored to receive Salute to Service Award, supports Roger Craig's HOF bid(18:00) Terrell Owens reminisces on iconic Sharpie celebration, discusses Kraft, Belichick HOF snubs(33:00) Where 49ers DT CJ West hopes to improve in his sophomore 49ers season(40:00) Jeff Garcia shares how Brock Purdy's ‘underdog' mentality keeps him competitive(50:00) Former 49ers DB Logan Ryan believes the 49ers found their next great nickel corner in Upton Stout Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Welcome to the Paint The Medical Picture Podcast, created and hosted by Sonal Patel, BA, CPMA, CPC, CMC, ICD-10-CM.Thanks to all of you for making this a Top 15 Medical Billing & Coding Podcast for 5 years on Feedspot.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sonal's 17th Season starts up and Episode 1 features a Newsworthy update on 5 new telehealth services in 2026.Sonal's Trusty Tip and compliance recommendations focus on audit plans for office visits rendered via telehealth.Spark inspires us all to reflect on beauty, abundance, and innovation based on the inspirational words of Kahlil Gibran.Check out Sonal's NAMAS article:https://namas.co/5-steps-to-update-your-audit-plan-for-office-visits-via-telehealth/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Paint The Medical Picture Podcast now on:Spotify:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://open.spotify.com/show/6hcJAHHrqNLo9UmKtqRP3X⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Apple Podcasts: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://podcasts.apple.com/us/podcast/paint-the-medical-picture-podcast/id153044217⁠7⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Amazon Music: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://music.amazon.com/podcasts/bc6146d7-3d30-4b73-ae7f-d77d6046fe6a/paint-the-medical-picture-podcas⁠t⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Find Paint The Medical Picture Podcast on YouTube:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UCzNUxmYdIU_U8I5hP91Kk7A⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Find Sonal on LinkedIn:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/sonapate/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠And checkout the website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://paintthemedicalpicturepodcast.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠If you'd like to be a sponsor of the Paint The Medical Picture Podcast series, please contact Sonal directly for pricing: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠PaintTheMedicalPicturePodcast@gmail.com⁠⁠

Fine, light, textured, yet strong. Donations, Merchandise, Newsletter, more: https://www.podrunner.com Groovelectric: Downloadable Soul https://www.groovelectric.com PLAYLIST 01. Diana May - Distant (Tim Kollberg Remix) 02. Roald Velden - Letting Go 03. Roald Velden - In My Dreams You're Always There 04. Martina Budde X Da Clubbmaster - Everybody Wants to Rule (Extended Mix) 05. Nipika & Haris V. - Staying Strong (Instrumental Mix) 06. Shyro & Anix Jay - Divine Waves (Devin Jay Remix) 07. Rockka & Kryptone (SL) - Resurgent (Morning Mix) 08. Coss Bocanegra - Somos Como Una Flor 09. Gad Ben David - Olympus 10. Deep Sure, Denis Vostru - Hummingbird 11. CMC & Silenta - Gonna Be Alright (Intrumental) 12. Cosmin Fogoros & Alex Modoi - Chasing Cars (Extended Mix) == Please support these artists == Podrunner is a registered trademark of Podrunner LLC. Music copyright © or CC the respective artists. All other material ©2006, 2026 by Podrunner LLC. For personal use only. Any unauthorized reproduction, editing, exhibition, sale, rental, exchange, public performance, or broadcast of this audio is prohibited. No part of Podrunner or its website and associated content may be used or reproduced in any manner for the purpose of training artificial intelligence technologies or systems.

49ers Wide Receiver Kendrick Bourne joins the guys to talk about the team's one of a kind of comradery in the locker room, how CMC has been such a huge part of that strong team foundation & if he believes there’s some kind of truth behind those practice field conspiracies in San Fran! Comedian Frank Caliendo swings by & goes over the impressions the guys always do on a regular basis! See omnystudio.com/listener for privacy information.

Covino & Rich broadcast live from Radio Row in San Francisco for Super Bowl 60 in this Best Of edition! The guys are joined by the Panthers QB Bryce Young & Running Back Rico Dowdle to talk all things about locker room dynamics & how the team will be back better than ever next year. 49ers Wide Receiver Kendrick Bourne joins the guys to talk about their one of a kind of comradery in the locker room, how CMC has been such a huge part of that strong team foundation + Comedian Frank Caliendo stops by! See omnystudio.com/listener for privacy information.

Thanks for listening to the podcast! If you are a first-time listener, welcome to the CMC family! Our heart behind this podcast is to serve, so we hope today's content equips and challenges you to be all that God has called you to be! If you would like to know more, please follow us on Instagram, Facebook, and YouTube.

Following Robert Saleh's hiring as Tennessee Titans head coach, sources confirmed to NBC Sports Bay Area that Raheem Morris will sign on as San Francisco's fifth defensive coordinator in the last five seasons. Also, in another top organizational move, Jed York announced Monday the promotion of Al Guido to the role of CEO. On this episode of "49ers Talk," Matt Maiocco sits down with Guido to discuss his promotion, his hard work in bringing Super Bowl LX to the Bay Area and how the 49ers' front office and coaching staff's synergy has provided stability that is rare in the NFL these days. They also touch upon the logistics required to host a Super Bowl twice in 10 years, and the possibility of the 49ers playing two international games this coming season. Matt also interviews talkSPORT commentator Will Gavin about his viral call of the "Skyy Bang Reverse Pass" play that was key to San Francisco's fourth-quarter comeback vs. the Eagles in NFC wild-card playoffs.--6:00 - 1-on-1 with newly promoted 49ers CEO Al Guido12:00 Guido's work on bringing Super Bowl LX to Levi's14:00 - Dynamic between the coaching staff and 49ers' front office19:00 - 49ers are in a window next season to play international home game or two20:00 - talkSPORT commentator Will Gavin breaks down viral call of 49ers play23:00 - More people have contacted CMC about the call than the actual play  Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Thanks for listening to the podcast! If you are a first-time listener, welcome to the CMC family! Our heart behind this podcast is to serve, so we hope today's content equips and challenges you to be all that God has called you to be! If you would like to know more, please follow us on Instagram, Facebook, and YouTube.

The cultivated meat industry has captured headlines and struggled with economics. Meanwhile, plant cell biomanufacturing is quietly solving the cost equation and approaching commercial launch. The question isn't whether cellular agriculture can work at scale. It's which applications will get there first, and what bioprocessing innovations will make it possible.In Part 2, we dive into the commercialization challenges that separate laboratory curiosity from market-ready products. Steven Lang tackles the hard questions: How do you replicate chocolate's complex flavor profile without traditional fermentation? What analytical infrastructure ensures product consistency and safety? And how do you build the right team and data foundation to navigate the journey from premium launch to commodity-scale production?Steven's background spanning Johnson & Johnson, Genentech, and Upside Foods gives him a unique perspective on what works and what doesn't when translating biopharma rigor to food applications. At California Cultured, he's applying those lessons to launch high-flavanol cocoa powder in 2026, with a clear roadmap to commodity cocoa and coffee thereafter.In this episode:The challenge of replicating chocolate's taste and fermentation in the lab (02:39)How plant cell culture differs from conventional farming and its advantages for safety and scalability (03:03)Analytical methods and equipment needed for consistent, safe, and high-quality cultured cocoa products (05:05)The potential for cell-based food to minimize heavy metals and other contaminants in chocolate (06:09)Environmental implications: tackling climate change, deforestation, and the realistic timeline for widespread adoption of lab-grown foods (06:50)Emerging opportunities beyond cocoa and coffee—saffron, ginseng, echinacea, and even lab-grown wood (08:40)Key advice for scientists and entrepreneurs interested in entering the cellular agriculture field (10:12)Building successful teams and robust data foundations in biotech startups (11:43)Key takeaway:Cellular agriculture's future isn't a single technology replacing conventional food production. It's multiple parallel approaches creating resilience in global food systems. The opportunity is clear: the technical principles you've mastered in biopharma translate directly to food applications, but the faster commercialization timelines and novel business models require rethinking what "stage-appropriate development" means.The question for bioprocess leaders is whether you'll help build the solutions to bridge the food production gap, or watch from the sidelines as food security becomes the defining challenge of our generation.Here is the previous conversation with Steven Lang:Episodes 55-56: Cultivated Meat: A Promising Future or an Inevitable Bubble? with Steven LangConnect with Steven Lang:LinkedIn: www.linkedin.com/in/steven-lang-b003406California Cultured Inc.: www.cacultured.comNext step:Need fast CMC guidance? → Get rapid CMC decision support hereSupport the show

On today's show Andrew and Bill react to the news that the rumors were true, and CMC members Zhang Youxia and Liu Zhenli are under investigation for corruption. Topics include: The timing of the announcement from the Defense Ministry, why this weekend's news inspired such a volume of reactions around the world, a history of Xi's crackdowns on the PLA, questions about rumors of a coup against Xi, reports that Zhang Youxia was working with the U.S., the PLA corruption heyday and its implications for what might come next, and various ways to think about the implications for Taiwan. At the end: The first batch of H-200s is approved for purchase, and the TikTok sale is approved as users lash out with censorship claims.

Thanks for listening to the podcast! If you are a first-time listener, welcome to the CMC family! Our heart behind this podcast is to serve, so we hope today's content equips and challenges you to be all that God has called you to be! If you would like to know more, please follow us on Instagram, Facebook, and YouTube.

In this episode of Inside Winemaking, Jim Duane speaks with Leigh Meyering of MyEnologist about the practical and analytical aspects of heat and cold stability in wine. The discussion focuses on how and why protein haze and tartrate instability occur, with an emphasis on white and rosé wines. Leigh explains the principles behind heat stability testing, protein denaturation, and the use of bentonite to prevent haze, as well as how stability concerns differ between red wines and lighter-colored styles. The conversation also addresses the sensory and chemical impacts of stabilization decisions, including common concerns around stripping, mouthfeel, and visual clarity in finished wines. The episode then moves into cold stability, detailing the Davis conductivity, DIT, and ISTC 50 tests and how to choose the appropriate method based on a winery's stabilization strategy. Leigh outlines the roles of traditional chilling and seeding, carboxymethyl cellulose (CMC), and mannoproteins, including their limitations and compatibility with protein stability. Throughout the discussion, Jim and Leigh emphasize correct sampling strategy, filtration level selection, and timing of tests to ensure results accurately represent the wine that will be bottled. Practical lab workflows, sample volume requirements, and real-world bottling considerations are covered to help winemakers reduce risk and avoid post-bottling stability issues. Leigh previously appeared on Inside Winemaking in May 2019 to discuss the founding and early development of her wine lab, MyEnologist, including its analytical services and role in supporting winemakers. This episode builds on that earlier conversation by applying lab-based analysis directly to cellar decision-making, with a focused, technical look at stability testing and intervention strategies used in modern winemaking.

We love to hear from our listeners. Send us a message. On this week's episode of the Business of Biotech -- on location at the J.P. Morgan Healthcare Conference -- we're speaking with Ron Cooper, CEO and Board Member at enGene, to unpack how he scaled Albireo from a small research shop to a global commercial company, and why he's now betting on nonviral gene therapy at enGene to help patients with non-muscle invasive bladder cancer keep their bladders. Cooper talks about the importance of keeping development, financing, and hiring in sync as biotech companies grow, his experiences surviving near-death cash deficits, the importance of investing early in CMC, and what to expect in 2026.  Access this and hundreds of episodes of the Business of Biotech videocast under the Business of Biotech tab at lifescienceleader.com. Subscribe to our monthly Business of Biotech newsletter. Get in touch with guest and topic suggestions: ben.comer@lifescienceleader.comFind Ben Comer on LinkedIn: https://www.linkedin.com/in/bencomer/

2026-01-26 | UPDATES #113 | “Treason” in the PLA? Xi's unprecedented purge — corruption, loyalty, and coup rumours. Today's story is not “just another corruption scandal” in China. This is the Chinese Communist Party reaching up into the absolute top of the People's Liberation Army — right into the room where war plans live — and yanking out two senior figures in one move. Top figures in fact. Beijing's official language is clipped. The implications are not. China's defence ministry says it has opened investigations into General Zhang Youxia — a vice chairman of the Central Military Commission, effectively the uniformed number two under Xi Jinping — and General Liu Zhenli, a CMC member and chief of the Joint Staff Department. The stated reason: “suspected serious violations of discipline and law.” (Reuters)----------SUPPORT THE CHANNEL:https://www.buymeacoffee.com/siliconcurtainhttps://www.patreon.com/siliconcurtain----------SOURCES: Xinhua: Defence ministry announcement (Jan 24, 2026). Xinhua / PLA Daily editorial summary (Jan 24, 2026). Reuters: Investigation details and context on PLA purges (Jan 24, 2026). Associated Press: Overview and recent purge timeline (Jan 24, 2026).Financial Times: Loyalty framing and “authority” angle (Jan 25, 2026). Washington Post: Scale of upheaval and command implications (Jan 25, 2026).Wall Street Journal: Reported additional allegations (unconfirmed by PRC statement) South China Morning Post: “Party purity” framing and political timing (Jan 25, 2026). Official explainer of the “CMC Chairperson Responsibility System” (SCIO, background).Reuters (background): Li Shangfu/Wei Fenghe expulsions (Jun 2024) and 2027 readiness reporting (Feb 2023). German Marshall Fund (background): Rocket Force shakeup (Aug 2023). Andrew Erickson (analysis aggregation; includes translated/linked primary text). Sinocism (analysis; discussion of messaging speed and implications). ----------SILICON CURTAIN LIVE EVENTS - FUNDRAISER CAMPAIGN Events in 2025 - Advocacy for a Ukrainian victory with Silicon Curtainhttps://buymeacoffee.com/siliconcurtain/extrasOur events of the first half of the year in Lviv, Kyiv and Odesa were a huge success. Now we need to maintain this momentum, and change the tide towards a Ukrainian victory. The Silicon Curtain Roadshow is an ambitious campaign to run a minimum of 12 events in 2025, and potentially many more. Any support you can provide for the fundraising campaign would be gratefully appreciated. https://buymeacoffee.com/siliconcurtain/extras----------

What happens when we move beyond oversimplified cell cultures and truly embrace the complexity of human biology? In this episode of the Smart Biotech Scientist Podcast, we explore how advanced 3D cell models are reshaping preclinical research—recreating human tissue microenvironments to better understand tumors, immunotherapies, and gene and cell therapies.David's guest is Catarina Brito, Principal Investigator at ITQB NOVA and Head of the Advanced Cell Models Laboratory at iBET and ITQB NOVA (Portugal). Her work bridges academia and industry through iBET, a unique partnering organization that integrates cell engineering, bioprocessing, and translational modeling.Catarina's pioneering models help both pharma leaders and startups predict drug resistance and immunogenicity earlier and more reliably, accelerating the path to safer, more effective therapies—well before clinical trials begin.Topics discussed:Understanding the contribution of stromal and immune cells to therapy outcomes in tumor microenvironments (03:42)Studying immune responses to gene therapy vectors with advanced neural models (04:31)Combining multi-omics and spatial data with AI for predictive biology and patient-specific digital twins (05:16)Catarina's advice: Start simple, let the biological question dictate model design, and avoid premature overengineering (06:53)Importance of reproducibility, process controls, and standardization in advanced models (08:10)How academic-industry collaborations drive model development, scalability, and real-world relevance (08:42)Common pitfalls: Overengineering, poor cell source selection, insufficient system validation (11:03)Next steps for precision medicine and translational research using advanced cell models (13:08)Want to know how leading scientists make advanced cell models actionable and collaborative for pharma breakthroughs? Tune in for practical strategies, real-world collaborations, and pitfalls to avoid as you scale your own translational research.Connect with Catarina Brito:LinkedIn: www.linkedin.com/in/catarina-brito-ibetAdvanced Cell Models Lab – iBET: www.ibet.pt/laboratories/advanced-cell-models-labNext step:Need fast CMC guidance? → Get rapid CMC decision support hereSupport the show

Thanks for listening to the podcast! If you are a first-time listener, welcome to the CMC family! Our heart behind this podcast is to serve, so we hope today's content equips and challenges you to be all that God has called you to be! If you would like to know more, please follow us on Instagram, Facebook, and YouTube.

What if the failure rate in clinical trials isn't about picking the wrong drug candidates—but about testing them in the wrong models?When you move cells from a 2D culture plate into a bioreactor, you're not simply scaling volume. You're fundamentally changing the biological context. Cell density shifts. Mass transfer dynamics evolve. Mechanical cues emerge. The cells sense these changes and respond—often in ways that derail strategies built on oversimplified assumptions.Most preclinical research still relies on flat plastic surfaces and animal models that miss critical aspects of human biology. The result? Therapeutics fail late in development because the models couldn't predict how human tissues would actually respond.In this episode, David Brühlmann speaks with Catarina Brito, Principal Investigator at ITQB NOVA and Head of the Advanced Cell Models Laboratory at iBET and ITQB NOVA in Portugal. Catarina's career-defining insight came early: studying glycan-protein interactions in murine versus human cells revealed that species differences weren't just nuances—they were fundamental gaps that could mislead entire research programs.Catarina and her team have developed neural, liver, and tumor models that capture the multicellular complexity and microenvironmental cues that 2D cultures cannot replicate. Her work creates preclinical models sophisticated enough to predict human responses while remaining scalable for drug development workflows.Highlights of the episode:Limitations of traditional 2D cell cultures and animal models in capturing realistic tissue behavior and therapeutic responses (06:27)Catarina Brito's personal scientific journey: from discovering model limitations to pioneering 3D culture systems in neural and liver tissues (04:19)How advanced 3D models recreate cell-to-cell interactions, tissue-specific microenvironments, diffusion gradients, and multicellular complexity (10:35)Regulatory movements toward reducing animal models, and the challenge of validating advanced alternatives for systemic biology studies (09:10)Key differences in designing bioreactors for various cell types, with practical examples from liver and neural models (15:16)The impact of scalable, robust 3D models on accelerating drug development and improving selection of candidate therapies (17:22)Key Takeaway:Bioprocess development starts when you choose the model that validates your therapeutic approach. If that model can't capture the biology that matters, every downstream optimization is built on a flawed foundation.In Part 2, Catarina reveals how 3D tumor microenvironments expose drug resistance mechanisms invisible in 2D cultures, and her vision for AI-powered digital twins enabling personalized medicine.Subscribe & Review:If this conversation changed how you think about preclinical model selection, leave a review on Apple Podcasts. Your reviews help other biotech scientists discover these insights.For more CMC development insights, visit smartbiotechscientist.com.Connect with Catarina Brito:LinkedIn: www.linkedin.com/in/catarina-brito-ibetAdvanced Cell Models Lab – iBET: www.ibet.pt/laboratories/advanced-cell-models-labNext step:Need fast CMC guidance? → Get rapid CMC decision support hereSupport the show

Seahawks, Broncos WIN.. Nix ankle; CMC injury

The biotech industry stands on the verge of a radical transformation thanks to artificial intelligence (AI) and machine learning (ML). But even the most sophisticated algorithms are only as smart as the data feeding them.David Brühlmann sits down with Troy Lionberger, Chief Business Officer at A-Alpha Bio, whose team has quietly shattered the data ceiling by measuring and curating more than 1.8 billion protein interactions. Troy Lionberger brings an insider's perspective from the frontlines of machine learning-powered drug discovery. From partnering with leading biotechs to redesigning classic antibodies for previously “impossible” targets, Troy's work pushes the edges of what's tractable in biologic therapeutics.What you'll hear in this episode:Limitations of public data sources like the Protein Data Bank and their impact on current protein engineering approaches (03:11)Why combining energetic (ΔG) and structural data matters for building predictive protein engineering models (05:43)A-Alpha Bio's approach to generating 1.8 billion protein interaction measurements for machine learning—what this enables today and what's possible next (06:30)Examples of how A-Alpha Bio's platform solves challenging therapeutic problems, such as optimizing molecules for 800+ HIV variants and engineering dual-specific antibodies (07:36)The ongoing debate: What capabilities should biotech companies keep in-house, and what works best outsourced to service providers? (09:59)The potential of synthetic epitopes as vital tools for training models beyond the Protein Data Bank—introducing the Synthetic Epitope Atlas (12:09)Key takeaways for scientists: the importance of diligence amidst rapidly evolving AI claims, and advice for accelerating R&D with the right data (14:57)Wondering how to move protein therapeutics from “interesting” to “impactful” without waiting for years of crystal structures? Listen in to learn how you can harness next-gen machine learning tools and custom datasets for your development projects.Connect with Troy Lionberger:LinkedIn: www.linkedin.com/in/troylionbergerA-Alpha Bio website: www.aalphabio.comNext step:Need fast CMC guidance? → Get rapid CMC decision support hereSupport the show

Thanks for listening to the podcast! If you are a first-time listener, welcome to the CMC family! Our heart behind this podcast is to serve, so we hope today's content equips and challenges you to be all that God has called you to be! If you would like to know more, please follow us on Instagram, Facebook, and YouTube.

Spadoni and Shasky discuss the Warriors win, Fred Warner's return and the guys play with some hypotheticals to show how desperate 49ers fans are to win the Super Bowl. Plus, who are guys that were traded that felt like they lived their career in one spot, like CMC?

In this edition of What the Bleep, Celtics head coach Joe Mazzulla goes viral for another excellent press conference, a young Eagles fan talks about a tough playoff loss, Jason Garrett had an unfortunate misspeak on CMC, a woman has a food snorting addiction, & more See omnystudio.com/listener for privacy information.

Antibody therapeutics have transformed modern medicine, but for many scientists, developing new candidates still feels like searching for a needle in a haystack—a slow, expensive, and unpredictable process. Structural biology and high-throughput data generation are now collapsing that haystack, offering unprecedented visibility into the molecular handshake that drives life: protein-protein interactions.In this episode, David Brühlmann sits down with Troy Lionberger, Chief Business Officer at A-Alpha Bio, for an in-depth discussion on protein-protein interactions and how advances in data generation and machine learning are transforming antibody discovery and drug development.Troy Lionberger shares his journey into biotechnology, challenges long-held beliefs about antibody development, and explains how Alphabio's high-throughput affinity measurements are shortening timelines and improving outcomes for therapeutic development.In this episode, you'll learn about:The historical and current challenges in characterizing these interactions at scale (06:22)How new technologies—especially high-throughput platforms—are changing the needle-in-the-haystack approach (08:40)A comparison of traditional in vivo and in vitro antibody discovery methods, along with their strengths and limitations (09:06)The evolving role of AI and machine learning in antibody discovery and lead optimization (12:11)Real-world examples of how A-Alpha Bio's approach is compressing years of work into months without sacrificing quality (13:58)The science behind A-Alpha Bio's AlphaSeq technology and how it leverages yeast display and genomics for large-scale affinity measurements (20:43)The practical affinity range the technology can measure, covering most therapeutic applications (23:25)Whether you're a scientist navigating CMC or a biotech professional curious about next-generation workflows, this episode offers practical insights into both traditional and emerging methodologies in the field.Connect with Troy Lionberger:LinkedIn: www.linkedin.com/in/troylionbergerA-Alpha Bio website: www.aalphabio.comNext step:Need fast CMC guidance? → Get rapid CMC decision support hereOne bad CDMO decision can cost you two years and your Series A. If you're navigating tech transfer, CDMO selection, or IND prep, let's talk before it gets expensive. Two slots open this month.Support the show

Hour 1: From underdogs to upset kings! The Niners storm Philly with a 23–19 win behind Brock Purdy’s clutch late TD and a jaw‑dropping trick‑play pass from Jauan Jennings to CMC, and KNBR 49ers insider Larry Krueger joins the show to break it all downSee omnystudio.com/listener for privacy information.

Christian McCaffrey put on a masterclass performance as the San Francisco 49ers went into Philadelphia and handled business against the Philadelphia Eagles.CMC was unstoppable, setting the tone early and taking over the game from start to finish. Physical runs, explosive plays, and straight dominance — this was a statement win on the road.

Hour 1: From underdogs to upset kings! The Niners storm Philly with a 23–19 win behind Brock Purdy’s clutch late TD and a jaw‑dropping trick‑play pass from Jauan Jennings to CMC, and KNBR 49ers insider Larry Krueger joins the show to break it all downSee omnystudio.com/listener for privacy information.

Thanks for listening to the podcast! If you are a first-time listener, welcome to the CMC family! Our heart behind this podcast is to serve, so we hope today's content equips and challenges you to be all that God has called you to be! If you would like to know more, please follow us on Instagram, Facebook, and YouTube.

In hour 2, Spadoni and Shasky discuss what to expect from CMC this weekend in Philly and what the offensive game plan should be for the 49ers.

Every Wednesday in January, Matt Harmon and Justin Boone take a look back at the 2025 fantasy season to find lessons they learned and can apply to the 2026 fantasy season. For today's pod the two look at their biggest takes from last summer to see what they got right and wrong at the QB and RB position. To end the show, Harmon debuts our new 'Dynasty Debates' segment where listeners send in their most pressing dynasty questions this fantasy offseason.(4:50) -Things we got WRONG at QB: Matthew Stafford, Bryce Young, JJ McCarthy(21:45) - Things we got WRONG at RB: Cowboys Backfield, Seahawks Backfield, Saquon Barkley(33:45) - Things we got RIGHT at QB: Drake Maye, Trevor Lawrence, Dak Prescott, Kyler Murray(41:50) - Things we got RIGHT at RB: Ashton Jeanty, CMC, TreVeyon Henderson, Chase Brown, RJ Harvey, Bijan Robinson(51:15) - Dynasty Debates: Matt and Justin answer your questions  Subscribe to the Yahoo Fantasy Forecast on your favorite podcast app:

For generations, silkworm pupae were discarded as waste from silk production. Now, KAICO is proving these organisms can function as highly efficient protein factories—producing complex vaccine antigens at yields and costs that challenge conventional bioreactor-based manufacturing. With a PCV2 oral vaccine already registered in Vietnam and a human norovirus vaccine preparing for Phase I clinical trials, the silkworm platform is moving from proof-of-concept to commercial reality.In Part 2, Masafumi Osawa, Business Development Lead at KAICO, walks us through the company's product pipeline, the regulatory landscape for this unprecedented platform, and why silkworm-based manufacturing could reshape global vaccine accessibility. From farm-scale validation to regulatory dialogue with Japan's PMDA, this episode bridges platform science with product development.Stops along our Silk Road to biomanufacturingKAICO's approach to expressing complex proteins, including oral and injectable vaccines for animals and clinical-stage human health products (00:40)Immune-enhancing feed additive for pigs against PCV2 (registered in Vietnam), companion animal products, and human norovirus vaccine entering Phase 1 trials (02:50)Advantages of silkworm-produced antigens for both injectable and oral vaccines, and comparison to plant-based systems (04:57)How silkworm production enables rapid scale-out and high-yield protein expression for global accessibility (05:34)Speed of vaccine development with the silkworm platform—example with SARS-CoV-2 recombinant protein produced in three months (08:08)Key regulatory differences between animal and human vaccine development, including country-specific classification and global harmonization efforts (09:14)Sustainability and distributed manufacturing potential of silkworm-based systems (11:10)Milestones toward the first human biologic produced in silkworms, with phase 1 trials starting soon (12:27)Protein yield per silkworm pupae—scalability advantages compared to conventional bioreactor approaches (14:04)Masafumi Osawa's thoughts on the future of silkworm-based biologics: from democratized therapies to personalized medicines (15:15)Want to know if silkworms can solve your tough protein expression problems? Tune in now to learn how KAICO's biotech is set to redefine what's possible for vaccine development, and how their distributed, cost-effective approach could open doors across sectors.Connect with Masafumi Osawa,:LinkedIn: www.linkedin.com/in/masa-osawaKAICO Ltd.: www.kaicoltd.jp/enNext step:Need fast CMC guidance? → Get rapid CMC decision support hereSupport the show

Thanks for listening to the podcast! If you are a first-time listener, welcome to the CMC family! Our heart behind this podcast is to serve, so we hope today's content equips and challenges you to be all that God has called you to be! If you would like to know more, please follow us on Instagram, Facebook, and YouTube.

For over 4,000 years, silkworms have connected civilizations through ancient trade routes. Now, KAICO Ltd., a Japanese biotech spin-off from Kyushu University, is transforming these creatures into living bioreactors capable of producing complex recombinant proteins and vaccine antigens—without the bioreactors, expensive media, or massive water consumption of conventional platforms.Masafumi Osawa, Business Development Lead at KAICO, brings an unconventional path to biotech. Trained in cultural anthropology with fieldwork experience in Indonesia, he witnessed firsthand the healthcare disparities that drive his current mission. After years in pharmaceutical business development at Towa Pharmaceutical, he joined KAICO to help scale a technology he believes could reshape global vaccine accessibility. His cross-cultural expertise now proves invaluable as KAICO expands internationally, with active partnerships in Vietnam and Thailand and growing interest from other regions.Episode highlights:Masafumi's transition from anthropology to biotech, and how cross-cultural expertise benefits global health collaborations. (04:15)The founding story of KAICO, spun out from Kyushu University and focused on recombinant proteins and vaccine antigen production (08:45)Step-by-step overview of the silkworm baculovirus expression system, including pupae handling and bioprocessing basics. (10:28)Practical differences between silkworms, E. coli, mammalian, and insect cell culture platforms—exploring advantages and drawbacks. (13:10)Strategies KAICO uses to control silkworm variability, including SPF grade sourcing, diet, environment, and documentation for pharmaceutical acceptance. (15:08)Production scalability: a single pupa can match 100–1000 ml of insect cell culture, with major implications for cost and environmental footprint. (16:42)Downstream harvesting and purification—how KAICO extracts and processes proteins from silkworm pupae, keeping methods largely familiar to traditional systems. (19:31)Regulatory and GMP challenges of using live organisms, and KAICO's approach to satisfying authorities and ensuring product consistency. (21:43)Whether you're curious about alternative biomanufacturing methods or want a transparent look at silkworm-based protein expression from research to the clinic, this episode delivers practical insights and thoughtful discussion.Connect with Masafumi Osawa:LinkedIn: www.linkedin.com/in/masa-osawaKAICO Ltd.: www.kaicoltd.jp/enNext step:Need fast CMC guidance? → Get rapid CMC decision support hereOne bad CDMO decision can cost you two years and your Series A. If you're navigating tech transfer, CDMO selection, or IND prep, let's talk before it gets expensive. Two slots open this month.Support the show

Thanks for listening to the podcast! If you are a first-time listener, welcome to the CMC family! Our heart behind this podcast is to serve, so we hope today's content equips and challenges you to be all that God has called you to be! If you would like to know more, please follow us on Instagram, Facebook, and YouTube.

Brian Baldinger joins The Roast to talk about the incredible game from Sunday night, what is impressing about Brock Purdy and CMC, as well as how the Niners can beat the Seahawks on Saturday night

Daniel and Chelsea discuss King Henry and CMC's performances in week 17, how nobody wants to win the NFC South, the Giants blowing the first overall pick and more topics!

Thanks for listening to the podcast! If you are a first-time listener, welcome to the CMC family! Our heart behind this podcast is to serve, so we hope today's content equips and challenges you to be all that God has called you to be! If you would like to know more, please follow us on Instagram, Facebook, and YouTube.

Thanks for listening to the podcast! If you are a first-time listener, welcome to the CMC family! Our heart behind this podcast is to serve, so we hope today's content equips and challenges you to be all that God has called you to be! If you would like to know more, please follow us on Instagram, Facebook, and YouTube, or visit our website CMChurch.com

Welcome to the Paint The Medical Picture Podcast, created and hosted by Sonal Patel, BA, CPMA, CPC, CMC, ICD-10-CM.Thanks to all of you for making this a Top 15 Medical Billing & Coding Podcast for 5 years on Feedspot.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sonal's 16th Season starts up and Episode 17 features Newsworthy updates on the month's fraud, waste, and abuse cases. Sonal's Trusty Tip and compliance recommendations focus on podiatry practices' evaluation and management services with modifier 25.Spark inspires us all to reflect on resilience based on the inspirational words of Winston Churchill.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Paint The Medical Picture Podcast now on:Spotify:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://open.spotify.com/show/6hcJAHHrqNLo9UmKtqRP3X⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Apple Podcasts: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://podcasts.apple.com/us/podcast/paint-the-medical-picture-podcast/id153044217⁠7⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Amazon Music: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://music.amazon.com/podcasts/bc6146d7-3d30-4b73-ae7f-d77d6046fe6a/paint-the-medical-picture-podcas⁠t⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Find Paint The Medical Picture Podcast on YouTube:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UCzNUxmYdIU_U8I5hP91Kk7A⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Find Sonal on LinkedIn:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/sonapate/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠And checkout the website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://paintthemedicalpicturepodcast.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠If you'd like to be a sponsor of the Paint The Medical Picture Podcast series, please contact Sonal directly for pricing: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠PaintTheMedicalPicturePodcast@gmail.com⁠

MNF Reactions: 49ers defeat Colts..

This episode explores the multifaceted nature of innovation in orthopedic surgery, from creative problem-solving in clinical practice to collaborating with industry on new device development. Dr. Robert Orfaly hosts a conversation with Dr. Amy Ladd, Chief of Stanford's Chase Hand & Upper Limb Center, a recognized leader in the field whose career includes pioneering research in thumb CMC arthritis, patents, and instrument design. Dr. Amy Ladd shares her perspective on fostering intellectual curiosity early in one's career, the process of turning a simple idea into intellectual property, and the evolving relationship between academic institutions, industry, and orthopedic surgeons. Practical advice is given for trainees, mid-career surgeons, and anyone inspired to pursue innovation, with stories ranging from creating specialized surgical instruments to applying motion analysis technology from upper limb research to optimizing golf swings. The episode also discusses the importance of networking across disciplines and the realities of developing and commercializing new medical devices, emphasizing that creativity and collaboration are central to advancing patient care. Host: Robert Orfaly, MD, MBA, FAAOS, Editor in Chief, AAOS Now  Guest: Amy Ladd, MD, FAAOS, Chief of Stanford's Chase Hand & Upper Limb Center; Chief of the Children's Hand Clinic at Lucile Salter Packard Children's Hospital at Stanfordand; and the Elsbach-Richards Professor of Surgery and Professor, by courtesy, of Medicine (Immunology & Rheumatology) and Surgery (Plastic and Reconstructive Surgery), at Stanford University Medical Center Production and Editing: MK Quinn Media

1:22 - Behind the FTF curtain.4:20 - Nick dealing with more fan venom then ever.13:12 - Silver-lining to the Chiefs season (if any)?17:13 - Time to for Nick to hop on the 49ers / Purdy bandwagon.20:20 - Kyle Shanahan should be in COTY conversations. CMC should get MVP votes.25:20.- Warriors talk27:54 - NBA expansion, which cities have a shot?30:21 - Real beef with Pablo Torre? Yes? No? Something in between?32:00 - Hoosiers34:30 - Grandpa Nick Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Thanks for listening to the podcast! If you are a first-time listener, welcome to the CMC family! Our heart behind this podcast is to serve, so we hope today's content equips and challenges you to be all that God has called you to be! If you would like to know more, please follow us on Instagram, Facebook, and YouTube, or visit our website CMChurch.com

Hall of Fame linebacker Patrick Willis, now an Alumni Ambassador for San Francisco after spending his entire career in the Bay, joins "49ers Talk" host Matt Maiocco to discuss the impact Super Bowl LX can have on the region and how its immersive, family-friendly festivities can be enjoyed by all who attend -- whether they have a ticket or not. Patrick and Matt also tackle the 49ers' surprising run this season and how overcoming adversity has been a hallmark of their success. Willis expands on what San Francisco needs to focus on in its final four games, as well as how his relationship with the organization affords him the opportunity to connect with upcoming great 49ers players. Jennifer Lee Chan also joins Matt to paint the NFC playoff picture, review roster changes and injury updates, plus detail San Francisco's final stretch.--(6:00) Who deserves the most credit for 49ers' 2025 success?(9:00) How 49ers stayed together in their pursuits this season(11:30) Breaking down the NFC playoff picture(17:00) How will the 49ers scheme for No. 1 draft pick QB Cam Ward this week?(23:30) Willis on 49ers' surprising 9-4 record, chances of reaching Super Bowl at home(25:30) Willis on how the 49ers reacted to all injuries this season(27:00) Willis shares advice he gives to young, older 49ers players(31:30) How would Patrick Willis in his prime face CMC?(38:00) 49ers Injury/Roster Updates Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Its Week 14 in the NFL, and the 49ers finally have reached their bye. As San Francisco players rest and recuperate, "49ers Talk" co-hosts Matt Maiocco and Jennifer Lee Chan take a pulse on the 49ers' season with just four regular-season games left. Jennifer, Matt, and later Greg Papa, discuss if Kyle Shanahan's current coaching staff is his best yet, and if that makes him a strong candidate for his first NFL Coach of the Year award. They also detail the 49ers' latest injuries and roster additions, then discuss if Christian McCaffrey's public support of Roger Craig can convince the Pro Football Hall of Fame committee to induct the legendary 49ers running back.--(2:00) How wind vs. Browns impacted Shanahan's decisions(3:00) 49ers injury updates, possible replacements(11:00) Could Eric Kendricks contribute to 49ers' defense after LB injuries?(15:00) Former 49ers RB Roger Craig announced as one of three finalists in senior category for Pro Football Hall of Fame(17:00) CMC offers public support for Craig's possible induction(24:00) Greg Papa on the 49ers being superbly coached in all three phases this season(28:00) Is this Shanahan's best coaching staff as a whole in his time with the 49ers?(33:00) It wouldn't shock Papa if Kendricks becomes MIKE linebacker to end the season(40:00) Could we possibly see two 49ers RBs enter HOF in the same year? (Gore, Craig) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.