Podcasts about CMC

MNF Reactions: 49ers defeat Colts..

This episode explores the multifaceted nature of innovation in orthopedic surgery, from creative problem-solving in clinical practice to collaborating with industry on new device development. Dr. Robert Orfaly hosts a conversation with Dr. Amy Ladd, Chief of Stanford's Chase Hand & Upper Limb Center, a recognized leader in the field whose career includes pioneering research in thumb CMC arthritis, patents, and instrument design. Dr. Amy Ladd shares her perspective on fostering intellectual curiosity early in one's career, the process of turning a simple idea into intellectual property, and the evolving relationship between academic institutions, industry, and orthopedic surgeons. Practical advice is given for trainees, mid-career surgeons, and anyone inspired to pursue innovation, with stories ranging from creating specialized surgical instruments to applying motion analysis technology from upper limb research to optimizing golf swings. The episode also discusses the importance of networking across disciplines and the realities of developing and commercializing new medical devices, emphasizing that creativity and collaboration are central to advancing patient care. Host: Robert Orfaly, MD, MBA, FAAOS, Editor in Chief, AAOS Now  Guest: Amy Ladd, MD, FAAOS, Chief of Stanford's Chase Hand & Upper Limb Center; Chief of the Children's Hand Clinic at Lucile Salter Packard Children's Hospital at Stanfordand; and the Elsbach-Richards Professor of Surgery and Professor, by courtesy, of Medicine (Immunology & Rheumatology) and Surgery (Plastic and Reconstructive Surgery), at Stanford University Medical Center Production and Editing: MK Quinn Media

Biomanufacturing has always dealt with the challenge of turning vast, complex datasets and intricate production steps into life-changing therapies. But when batch records multiply and process deviations loom, how do biotech teams make sense of it all? In this episode, we move beyond theory to the nuts and bolts of how AI - when thoughtfully deployed - can turn bioprocessing chaos into actionable intelligence, paving the way for the factory of the future.Our guest, Ilya Burkov, Global Head of Healthcare and Life Sciences Growth at Nebius AI, doesn't just talk about data wrangling and algorithms—he's spent years building tools and strategies to help scientists organize, contextualize, and leverage real-world datasets. Having worked across tech innovation and pharmaceuticals, Ilya Burkov bridges cutting-edge computation with the practical realities of CMC development and manufacturing, making him a trusted voice on how bioprocessing is rapidly changing.Highlights from the episode:Advice for biotech scientists on learning from innovations in other industries (00:02:21)Tackling the complexities of organizing huge and often unstructured datasets in bioprocessing (03:08)Techniques and tools to structure, label, and prepare data for AI—including Nebius's in-house tool, Tracto AI (06:24)Strategies for startups and small teams—how to begin implementing AI and what areas of bioprocessing to focus on first (10:12)The vision for the “factory of the future”: AI-driven, interconnected, and self-learning manufacturing environments (08:11)Navigating the decision between on-premise and cloud computing for scalable, cost-effective AI workloads (12:32)The importance of partnership between scientists and AI, emphasizing collaboration and data-driven decisions (00:15:47)Wondering how to kick off your own AI-enabled bioprocessing project, or what to insource versus outsource as you scale? This episode gives you a grounded starting point—minus the buzzwords and empty promises.Connect with Ilya Burkov:LinkedIn: www.linkedin.com/in/ilyaburkovContact email: ilya.burkov@nebius.comNebius: www.nebius.comIf this topic grabbed you, you'll love these related episodes focusing on advanced modeling, continuous manufacturing, and Digital TwinsEpisodes 213 - 214: From Developability to Formulation: How In Silico Methods Predict Stability Issues Before the Lab with Giuseppe LicariEpisodes 85 - 86: Bioprocess 4.0: Integrated Continuous Biomanufacturing with Massimo MorbidelliEpisodes 05 - 06: Hybrid Modeling: The Key to Smarter Bioprocessing with Michael SokolovEpisode 153 - 154: The Future of Bioprocessing: Industry 4.0, Digital Twins, and Continuous Manufacturing Strategies with Tiago MatosEpisodes 173 - 174: Mastering Hybrid Model Digital Twins: From Lab Scale to Commercial Bioprocessing with Krist GernaeyNext step:Need fast CMC guidance? → Get rapid CMC decision support hereSupport the show

Part 1 of today's show gets you ready for the fantasy football semifinals with waiver wire pickups that could win you a championship.Intro: (0:00)Waiver Wire Rebound (1:00): The most-dropped players worth picking back up. Shedeur Sanders was the 4th most-dropped QB but has a great finals matchup against Pittsburgh. Jayden Higgins was the 5th most-dropped WR despite 19 targets over three weeks before his dud - he faces the Raiders this week. Brian Robinson gives you CMC insurance. The 49ers defense was the 3rd most-dropped - they're playing the COLTS, why are people dropping them?Best Players Still Available: Bryce Young (19% owned) faces a limping Buccaneers team. Luther Burden III (17%) if healthy. Michael Carter (27%) could be a league-winner with Arizona's banged-up backfield - 14 carries last week. Colby Parkinson (22%) has TDs in 5 of his last 6 games. AJ Barner had 11 targets and 70 yards against the Rams last matchup.Dumpster Darlings Recap (10:57): Last week's best deep-league adds you missed. Kirk Cousins (8% owned) dropped 26.92 points. Colby Parkinson scored 22 points. The full lineup put up 143.92 points - these are championship-winning adds.Dolphins Bench Tua (13:55): Miami benched Tua Tagovailoa and it raises MASSIVE questions about their future. What does this mean for fantasy? For Miami's offseason? Is the Tua era over in South Beach?5 Teams That Could Trade for Joe Burrow (19:12): If Burrow is really fed up with the Bengals, here are the teams with motivation and assets to make a blockbuster move:Miami Dolphins - Need a big QB change in competitive AFC East. 11th pick + Tua + 2026 1st?New York Jets - No QB of the future, picking 5th overall. Can they send a package of picks?Las Vegas Raiders - Could have #1 overall pick. Is that enough to get Cincy talking?Philadelphia Eagles - If playoffs go like regular season for the offense, could they go all-in? Aggressive GM, Super Bowl roster.Minnesota Vikings - JJ McCarthy gamble didn't pay off. QB is only thing keeping them from being NFC North contenders. Honorable Mention: Arizona Cardinals - Kyler Murray out of favor, young enough to be trade centerpiece?Thursday Night Football Preview (31:39): Rams at Seahawks breakdown with key fantasy matchups and defensive rankings for each position.This is Part 1 of today's episode. Part 2 covers Quinn Hughes trade to Minnesota, Blue Jays offseason, and John Cena's last match fallout.

1:22 - Behind the FTF curtain.4:20 - Nick dealing with more fan venom then ever.13:12 - Silver-lining to the Chiefs season (if any)?17:13 - Time to for Nick to hop on the 49ers / Purdy bandwagon.20:20 - Kyle Shanahan should be in COTY conversations. CMC should get MVP votes.25:20.- Warriors talk27:54 - NBA expansion, which cities have a shot?30:21 - Real beef with Pablo Torre? Yes? No? Something in between?32:00 - Hoosiers34:30 - Grandpa Nick Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Thanks for listening to the podcast! If you are a first-time listener, welcome to the CMC family! Our heart behind this podcast is to serve, so we hope today's content equips and challenges you to be all that God has called you to be! If you would like to know more, please follow us on Instagram, Facebook, and YouTube, or visit our website CMChurch.com

Welcome to the Paint The Medical Picture Podcast, created and hosted by Sonal Patel, CPMA, CPC, CMC, ICD-10-CM.Thanks to all of you for making this a Top 15 Medical Billing & Coding Podcast for 5 Years on Feedspot. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sonal's 16th Season starts up and Episode 16 features a Newsworthy update on the PEPPER program. It's back.Sonal's Trusty Tip and compliance recommendations focus on skin substitutes and the upcoming LCDs.Spark inspires us all to reflect on resilience based on the inspirational words of Thomas Edison.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Paint The Medical Picture Podcast now on:Spotify: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://open.spotify.com/show/6hcJAHHrqNLo9UmKtqRP3X⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Apple Podcasts: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://podcasts.apple.com/us/podcast/paint-the-medical-picture-podcast/id153044217⁠7⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Amazon Music: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://music.amazon.com/podcasts/bc6146d7-3d30-4b73-ae7f-d77d6046fe6a/paint-the-medical-picture-podcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Find Paint The Medical Picture Podcast on YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UCzNUxmYdIU_U8I5hP91Kk7A⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Find Sonal on LinkedIn:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/sonapate/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠And checkout the website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://paintthemedicalpicturepodcast.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠If you'd like to be a sponsor of the Paint The Medical Picture Podcast series, please contact Sonal directly for pricing: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠PaintTheMedicalPicturePodcast@gmail.com⁠⁠⁠

Unlock your Week 16 fantasy football edge with 12 Must-Know Fantasy Football Stats for NFL Week 16! Keith Flemming and Kacey Kasem break down 12 must-know stats and trends to help you crush your lineup and waiver wire decisions. Whether you're rolling after a big Week 14 or battling back from a tough week, these insights give you the upper hand in your fantasy football leagues. - 12 Must-Know Fantasy Football Stats for Week 16 to Gain an Edge!Intro (00:00) Josh Allen (01:19) Mike Tomlin (03:53)Jason Myers (05:08)Trevor Lawrence (06:50)Jameson Williams (08:08)Treyvon Henderson (10:38) Trey McBride (12:51)Jaxson Dart (15:13)Colby Parkinson (16:50)Alec Pierce (19:05)Tight Ends (21:18)CMC (25:02)Subscribe for expert fantasy football advice, rankings, waiver wire pickups, and trade tips all season long! Subscribe for expert fantasy football advice, rankings, waiver wire pickups, and trade tips all season long! Like, comment, and hit the notification bell so you never miss our latest insights.

Downtown Columbus is changing rapidly, and local leaders are working to build a safer, more vibrant, and more connected urban core. We bring together experts from public safety, urban development, and community strategy to explore what it will take to strengthen the heart of the city. From new safety initiatives to long-term planning and partnership models, the conversation highlights how a thriving downtown Columbus drives Central Ohio's regional success. Featuring: Greg Davies, CEO, Downtown Columbus, Inc. Robin Davis, Executive Director, Safer Downtown Smith Weir, Deputy Chief of the Columbus Division of Police The host is Dawn Tyler Lee, former Deputy Chief of Staff with The City of Columbus, and Founder and CEO, Forrest Street Consulting. Amy Taylor, President of Downtown Columbus, Inc., presents opening remarks on the state of downtown. This forum was sponsored by Downtown Columbus, Inc., Event Marketing Strategies, MKSK, and The Robert Weiler Company. The presenting sponsor of the CMC livestream was The Center for Human Kindness at the Columbus Foundation. CMC's livestream partner was The Columbus Dispatch. This forum was also supported by The National Veterans Memorial and Museum. If you would like to keep exploring this week's forum topic, our partners at The Columbus Metropolitan Library recommend reading Walkable City: How Downtown Can Save America One Step at a Time by Jeff Speck (2022). This forum was recorded before a live audience at The National Veterans Memorial and Museum in Columbus, Ohio on December 17, 2025.

Across biotech labs, researchers swim in oceans of process data: sensor streams, run records, engineering logs, and still, crucial decisions get stuck in spreadsheets or scribbled into fading notebooks. The challenge isn't having enough information, it's knowing which actions actually move the needle in cell culture productivity, process stability, and faster timelines.This episode, David Brühlmann brings on Ilya Burkov, Global Head of Healthcare and Life Sciences Growth at Nebius AI. With a career spanning NHS medicine, regenerative research, and cloud infrastructure, Ilya Burkov has lived the leap from microscope to server room. He's seen firsthand how digital twins, autonomous experimentation, and cloud-first strategies are shifting the way biologics are developed and scaled.Topics discussed:Shifting from experimental-based to computational bioprocess development, and the evolving role of human expertise vs. AI (02:48)Ilya Burkov's journey from medicine and orthopedics to AI and cloud infrastructure (04:15)Solving data silos and making real-time decisions with digital twins and automated analytics (06:36)The impact of AI-driven lab automation and robotics on drug discovery timelines (08:51)Using AI to accelerate cell line selection, cloning, and protein sequence optimization (10:12)Why wet lab experimentation is still essential, and how predictive modelling can reduce failure rates (11:15)Reducing costs and accelerating development by leveraging AI in process screening and optimization (12:32)Strategies for smaller companies to effectively store and manage bioprocess data, including practical advice on cloud adoption and security (14:30)Application of AI and digital twins in scale-up processes, and connecting diverse data types like CFD simulations and process data (17:18)The ongoing need for human expertise in interpreting and qualifying data, even as machine learning advances (19:09)Wondering how to stop your own data from gathering dust? This episode unpacks practical strategies for storing and leveraging your experimental records - whether you're in a major pharma or a small startup with limited tech resources.Connect with Ilya Burkov:LinkedIn: www.linkedin.com/in/ilyaburkovContact email: ilya.burkov@nebius.comNebius: www.nebius.comIf this topic grabbed you, you'll love these related episodes focusing on advanced modeling, continuous manufacturing, and Digital TwinsEpisodes 213 - 214: From Developability to Formulation: How In Silico Methods Predict Stability Issues Before the Lab with Giuseppe LicariEpisodes 85 - 86: Bioprocess 4.0: Integrated Continuous Biomanufacturing with Massimo MorbidelliEpisodes 05 - 06: Hybrid Modeling: The Key to Smarter Bioprocessing with Michael SokolovEpisode 153 - 154: The Future of Bioprocessing: Industry 4.0, Digital Twins, and Continuous Manufacturing Strategies with Tiago MatosEpisodes 173 - 174: Mastering Hybrid Model Digital Twins: From Lab Scale to Commercial Bioprocessing with Krist GernaeyNext step:Need fast CMC guidance? → Get rapid CMC decision support hereSupport the show

Keskustelut Ukrainan tilanteesta ja mahdollisesta rauhansuunnitelmasta jatkuivat eilen Berliinissä. Mukana olivat Yhdysvaltojen ja Ukrainan lisäksi EU, Nato ja monet eurooppalaiset maat. Otettiinko askelia rauhaa kohti? Berliinistä raportoi Eurooppa-kirjeenvaihtaja Anna Karismo ja studiossa keskustelevat johtava asiantuntija Jyrki Ruohomäki valtiollisesta siviilikriisinhallinnan asiantuntijaorganisaatio CMC:stä sekä vanhempi asiantuntija Mikko Patokallio rauhanrakennusjärjestö CMI:stä. Eduskunta päättää tänään hallituksen esityksestä suden ympärivuotisen rauhoituksen poistamisesta ja kannanhoidollisen metsästyksen sallimisesta. Lakiesityksestä on noussut poru etenkin sen jälkeen, kun maa- ja metsätalousvaliokunta teki siihen lisäyksen, joka sallisi myös karhun ja ilveksen kannanhoidollisen metsästyksen. Keskustelemassa valiokuntaan kuuluvat kansanedustajat Ritva Elomaa (ps.), Piritta Rantanen (sd.) ja Veronika Honkasalo (vas.). Länsirata-hankkeen jatkosta Salon ja Lohjan valtuustojen eilisten päätösten jälkeen kertoo Länsirata Oy:n toimitusjohtaja Pekka Ottavainen. Milano-Cortinan helmikuisten talviolympialaisten valmisteluiden lukuisista vastoinkäymisistä tekee selkoa toimittaja Jenna Vehviläinen Roomasta. Juontaja Markus Liimatainen. Tuottaja Anna-Maria Haarala, toimittajat Anssi Väisänen ja Mari Sarolahti.

Developing complex biologics and advanced therapies is historically time-consuming and material-intensive—but computational modeling is reshaping the formulation landscape.In this episode of Life Science Solutions, host Chris Adkins is joined by Andrea Arsiccio, PhD, Senior Scientist and Team Lead In Silico at Coriolis Pharma, to discuss how in silico modeling is revolutionizing the assessment of developability and formulation strategies for new drug products.Andrea breaks down how Coriolis Pharma combines physics-based models and Artificial Intelligence with traditional wet lab experimentation to predict molecule behavior, identify liabilities early, and solve complex problems like aggregation and viscosity.Topics Include:Defining In Silico: Understanding the spectrum from mechanistic models and molecular dynamics to AI and machine learning.Accelerating Development: How computational tools reduce the need for animal testing and save precious material in early-phase development.The "Why" Behind the "What": Using modeling to uncover the specific mechanisms causing instability or aggregation.The Hybrid Approach: Validating digital predictions with high-throughput wet lab screening for a robust formulation strategy.Regulatory Perspectives: How the FDA and EMA are viewing AI data and the importance of establishing model credibility.Expansion: Coriolis Pharma's growth into the US market and their new capabilities in Research Triangle Park.Whether you are a formulation scientist, a CMC leader, or a regulatory professional, this episode provides a fascinating look at how digital twins and computational strategies are de-risking the path to market for life-saving therapies.

JMToWin from One Week Season walks us through the Week 15 DFS slate from a GPP perspective, shares his top plays at each position, and then builds a DraftKings lineup using some of his favorite building blocks. In the second half, ShipMyMoney from Run The Sims shares sneaky stacks for Week 15 tournaments and spots with input volatility.

Hall of Fame linebacker Patrick Willis, now an Alumni Ambassador for San Francisco after spending his entire career in the Bay, joins "49ers Talk" host Matt Maiocco to discuss the impact Super Bowl LX can have on the region and how its immersive, family-friendly festivities can be enjoyed by all who attend -- whether they have a ticket or not. Patrick and Matt also tackle the 49ers' surprising run this season and how overcoming adversity has been a hallmark of their success. Willis expands on what San Francisco needs to focus on in its final four games, as well as how his relationship with the organization affords him the opportunity to connect with upcoming great 49ers players. Jennifer Lee Chan also joins Matt to paint the NFC playoff picture, review roster changes and injury updates, plus detail San Francisco's final stretch.--(6:00) Who deserves the most credit for 49ers' 2025 success?(9:00) How 49ers stayed together in their pursuits this season(11:30) Breaking down the NFC playoff picture(17:00) How will the 49ers scheme for No. 1 draft pick QB Cam Ward this week?(23:30) Willis on 49ers' surprising 9-4 record, chances of reaching Super Bowl at home(25:30) Willis on how the 49ers reacted to all injuries this season(27:00) Willis shares advice he gives to young, older 49ers players(31:30) How would Patrick Willis in his prime face CMC?(38:00) 49ers Injury/Roster Updates Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

12-11 Dirty Work Hour 1: Kyle Shanahan joins the show with the latest on the health of CMC and the feel of the team after the latest BYE in 49ers historySee omnystudio.com/listener for privacy information.

Computational methods can predict stability issues before the lab. But how do you actually implement these approaches in your formulation workflow? From excipient selection to long-term stability prediction, in silico tools are transforming how biotech teams develop robust formulations while reducing costly trial-and-error cycles.In Part 2, Giuseppe Licari, Principal Scientist in Computational Structural Biology at Merck KGaA, returns to share practical implementation strategies for integrating computational methods into biologics formulation development. Giuseppe reveals how molecular dynamics simulations guide excipient selection, where current methods hit their limits, and how emerging AI capabilities are expanding what's possible in formulation prediction.Whether you're at a well-resourced pharma company or a lean startup, Giuseppe offers actionable guidance for leveraging computational tools to predict protein behavior, optimize formulations, and accelerate your development timeline.Topics covered:Predicting protein aggregation and excipient interactions before manufacturing (00:45)Using molecular dynamics to understand protein behavior over time and in different environments (03:03)The interplay between computational predictions and experimental stability studies (04:49)The limitations of current in silico methods for predicting long-term stability (05:08)Emerging use of AI and machine learning to predict protein properties and improve developability (06:36)Future possibilities: Generative AI for protein design and formulation prediction (08:06)Advice for small companies: leveraging software-as-a-service and external partners to access computational tools (09:55)The impact of increasing computational power on the field's evolution (11:12)Most important takeaway: being open and curious about new computational techniques in biotech formulation (12:08)Discover how to bridge computational predictions with experimental validation, navigate the current limitations of in silico stability forecasting, and position your organization to benefit from AI-driven formulation development, regardless of your resource constraints.Connect with Giuseppe Licari to continue the conversation and explore how computational approaches can solve your formulation challenges before you ever step into the lab.Connect with Giuseppe Licari:LinkedIn: www.linkedin.com/in/giuseppe-licariNext step:Need fast CMC guidance? → Get rapid CMC decision support hereSupport the show

12-11 Dirty Work Hour 1: Kyle Shanahan joins the show with the latest on the health of CMC and the feel of the team after the latest BYE in 49ers historySee omnystudio.com/listener for privacy information.

What happens when a modular construction company leads with people first? Jon Scott of Creative Modular Construction joins the show to share how their motto—“We build people. We build buildings.”—is more than a slogan; it's the engine behind their remarkable growth. Jon walks through how CMC develops leaders on the shop floor, supports individuals from all backgrounds, and creates a culture where trust, purpose, and personal transformation translate directly into performance. We also discuss how CMC's people-first mindset has made it easier to adopt new processes and technologies (like Strucsoft) as they scale, blending craftsmanship, innovation, and culture into a resilient modular workflow. You'll Learn: How CMC builds a people-first culture that drives productivity and retention • Why investing in personal growth leads to stronger teams and better outcomes • How trust and purpose accelerate technology adoption and process improvements • What culture-building looks like in a fast-paced modular fabrication environment • How CMC is evolving its workflows as it scales its modular operations A powerful episode for anyone interested in modular construction, leadership development, or building high-performing teams through culture. MEET OUR GUEST Jonathan Scott serves as the Lead Draftsman at Creative Modular Construction, where he oversees the design and drafting behind a wide range of modular building projects. With a deep understanding of construction, engineering coordination, and practical field needs, Jonathan is the bridge between imagination and execution—translating concepts into clear, buildable plans that crews can trust. He's passionate about improving processes, solving complex layout challenges, and helping push the modular industry forward through smarter design. Outside of work, Jonathan enjoys life with his family and doing outreach in his community, and brings a grounded, faith-driven perspective to both his personal and professional life. TODD TAKES Building People Builds Performance CMC's commitment to “building people” isn't just a cultural slogan—it's a strategic advantage. When you invest in purpose, stability, and real community, people show up differently. They're engaged, they grow, and the work improves. Culture isn't an add-on for them; it's the engine behind everything they do. Trust Is the Foundation of Tech Adoption Introducing new tools like Strucsoft can be uncomfortable, but CMC's people leaned in because they trust the leadership guiding those decisions. That trust removes friction and accelerates adoption. When your team believes you're making choices that truly help them, change becomes something they embrace—not resist. When Purpose Meets Technology, Growth Takes Off The jump from producing two buildings in three days to three buildings in a single day is incredible. It's what happens when a clear mission, a supportive culture, and the right digital tools align. CMC shows that innovation isn't just about software—it's about creating a system where people and technology elevate each other.   More Resources  Thanks for listening! Please be sure to leave a rating and/or review and follow up our social accounts. Bridging the Gap Website Bridging the Gap LinkedIn Bridging the Gap Instagram Bridging the Gap YouTube Todd's LinkedIn   Thank you to our sponsors! Graitec North America Graitec North America LinkedIn Autodesk's Website   Other Relevant Links: Creative Modular Construction Website  

Welcome to the Paint The Medical Picture Podcast, created and hosted by Sonal Patel, CPMA, CPC, CMC, ICD-10-CM.Thanks to all of you for making this a Top 15 Medical Billing & Coding Podcast for 5 Years on Feedspot. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sonal's 16th Season starts up and Episode 15 features a Newsworthy update on the OIG Work Plan for November 2025.Sonal's Trusty Tip and compliance recommendations focus on chronic care management documentation.Spark inspires us all to reflect on resilience based on the inspirational words of Edmund Hillary.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Paint The Medical Picture Podcast now on:Spotify: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://open.spotify.com/show/6hcJAHHrqNLo9UmKtqRP3X⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Apple Podcasts: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://podcasts.apple.com/us/podcast/paint-the-medical-picture-podcast/id153044217⁠7⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Amazon Music: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://music.amazon.com/podcasts/bc6146d7-3d30-4b73-ae7f-d77d6046fe6a/paint-the-medical-picture-podcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Find Paint The Medical Picture Podcast on YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UCzNUxmYdIU_U8I5hP91Kk7A⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Find Sonal on LinkedIn:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/sonapate/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠And checkout the website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://paintthemedicalpicturepodcast.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠If you'd like to be a sponsor of the Paint The Medical Picture Podcast series, please contact Sonal directly for pricing: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠PaintTheMedicalPicturePodcast@gmail.com⁠⁠

In a rare joint appearance, the mayors of Columbus, Findlay, Lima, and Toledo—Andrew J. Ginther, Christina Muryn, Sharetta Smith, and Wade Kapszukiewicz—take the stage for a powerful conversation on the future of urban leadership in Ohio. Together, these four leaders represent more than a million Ohioans—nearly 10% of the state's population. From economic growth and urban development to transit, public safety, and civic engagement, they share strategies for building stronger, more connected, and more resilient cities. Featuring: Andrew J. Ginther, Mayor, City of Columbus Christina Muryn, Mayor, City of Findlay Sharetta Smith, Mayor, City of Lima Wade Kapszukiewicz, Mayor, City of Toledo Your host is Stacia Naquin, News Anchor, WBNS 10TV. This forum was sponsored by The Ohio State University, The Ohio Mayors Alliance, and The Robert Weiler Company. The presenting sponsor of the CMC livestream was The Center for Human Kindness at the Columbus Foundation. CMC's livestream partner was The Columbus Dispatch. This forum was supported by Downtown Columbus, Inc. and The National Veterans Memorial and Museum. If you'd like to keep exploring this week's forum topic, our partners at The Columbus Metropolitan Library recommend reading "Silicon Heartland: Transforming the Midwest from Rust Belt to Tech Belt," by Rebecca A. Fannin (2023).  This forum was recorded before a live audience at The National Veterans Memorial and Museum in Columbus, Ohio on December 10, 2025.

In Part 2 of the 2026 pipeline series, host Carolyn Liptak welcomes Dr. Amanda Frick, Senior Clinical Manager, Strategic Clinical Intelligence at Vizient, to explore the advanced therapies pipeline: cell therapies, gene therapies, tissue-engineered products, and combination advanced therapy products. The discussion explores major pipeline trends, six leading products to watch, and the growing innovation expected to shape clinical practice in 2026.   Guest speakers:  Amanda Frick, PharmD, BCPS Senior Clinical Manager, Strategic Clinical Intelligence Spend Management Vizient Host: Carolyn Liptak, MBA, BS Pharm Pharmacy Executive Director Center for Pharmacy Practice Excellence (CPPE) Vizient    Show Notes: [00:05] — Introduction Announcer opens the episode. Host Carolyn Liptak introduces the focus on advanced therapies: cell & gene therapies, tissue-engineered products, and combination products. Guest: Dr. Amanda Frick, Senior Clinical Manager, Strategic Clinical Intelligence at Vizient. [01:07] — Defining Advanced Therapies FDA groups cell and gene therapies within advanced therapies. Total FDA-approved advanced therapies: 46. Amanda monitors 29 drug-like therapies within that group. [02:01] — Pipeline Size and Approval Activity S. pipeline: 264 agents in development. About 10 agents approach FDA decision annually. Actual approvals: 5–7 per year on average. [02:56] — Big-Picture Trends in Cell & Gene Therapy Oncology dominates 40–50% of all CGTs in development. Expanding into autoimmune, neurology, and earlier-phase therapies for diabetes, angina, osteoarthritis. Movement toward allogeneic ("off-the-shelf") therapies Designed to overcome limits of autologous cell manufacturing. Reduces wait time and manufacturing failures. Resurgence of therapeutic vaccines Currently 3 approved (Sipuleucel-T, Talimogene, Papzimeos ). 20+ vaccines in the pipeline, largely targeted to cancer. CE program coming Jan 29. [06:13] — Therapy #1:  Tabelecleucel or Tab-cel (Allogeneic EBV-Specific T-Cell Therapy) First allogeneic T-cell therapy expected in the U.S. For EBV-positive post-transplant lymphoproliferative disorder (PTLD). “Off-the-shelf” and donor-derived. [07:07] — Clinical Need & Outcomes Currentstandard of care: rituximab. After relapse, survival

What if you could predict formulation failures before ever touching a pipette? Computational approaches are revolutionizing biologics development, replacing trial-and-error experimentation with predictive intelligence that catches stability issues early and accelerates your path from candidate selection to clinic.In this episode, David Brühlmann welcomes Giuseppe Licari, Principal Scientist in Computational Structural Biology at Merck KGaA. A chemist by training, Giuseppe transitioned from wet lab experimentation to the predictive power of in silico modeling. Today, he operates at the intersection of computational biology and CMC development, using digital tools to screen candidates for developability, predict formulation challenges, and de-risk development programs before committing resources to the lab.Discover how computational methods are transforming the way biotech companies approach developability assessment and formulation strategy:Why maximizing shelf life isn't always necessary in early development phases (02:56)The critical role of communication between computational and bench scientists (06:46)Core properties to assess for developability, including hydrophobicity, aggregation, charge, and immunogenicity (11:06)How accurate are in silico predictions, and where do they add the most value? (13:23)The limitations and strengths of machine learning and physics-based models in predicting protein behavior (15:19)The differences between developability, formulation development, and formulatability, and the value of early cross-functional collaboration (17:17)When to use platform formulations and when tailored approaches are needed for complex molecules (19:25)The advantages of using computational methods at any stage, especially for de-risking strategies (20:13)Listen in for practical strategies for integrating in silico predictions into your developability and CMC workflows, catching stability issues before the lab, and making smarter development decisions that save time, material, and money.Connect with Giuseppe Licari:LinkedIn: www.linkedin.com/in/giuseppe-licariNext step:Need fast CMC guidance? → Get rapid CMC decision support hereOne bad CDMO decision can cost you two years and your Series A. If you're navigating tech transfer, CDMO selection, or IND prep, let's talk before it gets expensive. Two slots open this month.Support the show

Its Week 14 in the NFL, and the 49ers finally have reached their bye. As San Francisco players rest and recuperate, "49ers Talk" co-hosts Matt Maiocco and Jennifer Lee Chan take a pulse on the 49ers' season with just four regular-season games left. Jennifer, Matt, and later Greg Papa, discuss if Kyle Shanahan's current coaching staff is his best yet, and if that makes him a strong candidate for his first NFL Coach of the Year award. They also detail the 49ers' latest injuries and roster additions, then discuss if Christian McCaffrey's public support of Roger Craig can convince the Pro Football Hall of Fame committee to induct the legendary 49ers running back.--(2:00) How wind vs. Browns impacted Shanahan's decisions(3:00) 49ers injury updates, possible replacements(11:00) Could Eric Kendricks contribute to 49ers' defense after LB injuries?(15:00) Former 49ers RB Roger Craig announced as one of three finalists in senior category for Pro Football Hall of Fame(17:00) CMC offers public support for Craig's possible induction(24:00) Greg Papa on the 49ers being superbly coached in all three phases this season(28:00) Is this Shanahan's best coaching staff as a whole in his time with the 49ers?(33:00) It wouldn't shock Papa if Kendricks becomes MIKE linebacker to end the season(40:00) Could we possibly see two 49ers RBs enter HOF in the same year? (Gore, Craig) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Join Ryan Wormeli and Pat Fitzmaurice as they tackle YOUR questions LIVE on Discord on the 1st Tuesday evening of each month at 5 PM ET at fantasypros.com/chat. The fellas break down some changes to the dynasty trade value chart before diving into your questions in the second half of the show! Timestamps: (May be off due to ads) Intro - 0:00:00 QB Ranking Changes - Drake Maye - 0:03:20 JJ McCarthy - 0:08:45 Reality Sports Online - 0:12:50 RB Ranking Changes - Omarion Hampton, Breece Hall - 0:13:45 WR Ranking Changes - JSN, George Pickens, Christian Watson - 0:18:47 TE Rankings Changes - Loveland, Terrance Ferguson, Isaiah Likely - 0:26:39 FantasyPros Trade Analyzer - 0:31:18 What To Do With Marshawn Lloyd and Jordan Mason - 0:23:26 Is My Roster Ready to Win? - 0:35:18 Loaded at WR, but Struggling at RB - 0:38:52 Rebuilding, but what do I do at QB? - 0:43:50 FantasyPros Discord - 0:49:13 Am I Overpaying for Brock Bowers? - 0:49:43 Sutton + Picks for Darnold and Waddle? - 0:53:25 Picks for CMC & Waddle? - 0:54:30 Which Keeper for 2026? - 0:55:19 Which Value QB Should I Trade Addison For? - 0:56:47 Addison & Two 26 1st's for Justin Jefferson - 0:58:13 When Should Dynasty Trade Deadlines Be? - 1:00:11 Jaylen Warren & Chris Godwin for a 2026 1st? - 1:02:36 Is This The Worst It Gets for Monangi? - 1:02:50 Helpful Links: Reality Sports Online - By now, most of you have probably heard of Reality Sports Online, the powerful Fantasy Sports platform where Owners get to build and manage their Fantasy team like an NFL General Manager. But, the question is, have you tried it? It’s time to go see what all the buzz in the dynasty community is about. If you like what you see, use the promo code "FANTASYPROS" to receive a 10% discount on your team or league today! Fantasy Just Got Real at RealitySportsOnline.com. Dynasty Rookie Draft Simulator - Our Dynasty Rookie Draft Simulator lets you complete a mock in minutes with no waiting between picks! Customize your league settings to match your league’s exact format. Premium subscribers can test trade scenarios by mocking with their traded draft picks. Prepare for rookie drafts AND dynasty startup drafts in one place! Use the Dynasty Rookie Draft Simulator to dominate your rookie draft today at fantasypros.com/simulator! Trade Analyzer - Evaluate trades with confidence using FantasyPros' Trade Analyzer. Instantly see the impact of trades on your team and get expert recommendations. Whether you're making a 2-for-1 deal or swapping a couple draft picks for that stud who will help you win now, the Trade Analyzer will help you optimize your roster and make smarter decisions. Try the Trade Analyzer today at fantasypros.com/myplaybook or on the Fantasy Football My Playbook app and dominate your league! Join us on Discord - Join our FantasyPros Discord Community! Chat with other fans and get access to exclusive AMAs that wind up on our podcast feed. Come get your questions answered and BE ON THE SHOW at fantasypros.com/chatSee omnystudio.com/listener for privacy information.

Welcome to the Paint The Medical Picture Podcast, created and hosted by Sonal Patel, BA, CPMA, CPC, CMC, ICD-10-CM.Thanks to all of you for making this a Top 15 Medical Billing & Coding Podcast for 5 years on Feedspot.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sonal's 16th Season starts up and Episode 14 features a Newsworthy update on World AIDS Day.Sonal's Trusty Tip and compliance recommendations focus on a new Medicare hospice outpatient services edit.Spark inspires us all to reflect on resilience based on the inspirational words of Marcus Aurelius.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Paint The Medical Picture Podcast now on:Spotify:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://open.spotify.com/show/6hcJAHHrqNLo9UmKtqRP3X⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Apple Podcasts: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://podcasts.apple.com/us/podcast/paint-the-medical-picture-podcast/id153044217⁠7⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Amazon Music: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://music.amazon.com/podcasts/bc6146d7-3d30-4b73-ae7f-d77d6046fe6a/paint-the-medical-picture-podcas⁠t⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Find Paint The Medical Picture Podcast on YouTube:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UCzNUxmYdIU_U8I5hP91Kk7A⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Find Sonal on LinkedIn:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/sonapate/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠And checkout the website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://paintthemedicalpicturepodcast.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠If you'd like to be a sponsor of the Paint The Medical Picture Podcast series, please contact Sonal directly for pricing: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠PaintTheMedicalPicturePodcast@gmail.com

The arts are more than inspiration—they're critical infrastructure. Across Central Ohio, cultural organizations are using shared data and collaborative evaluation to show how the arts drive workforce readiness, economic development, public health, and community well-being. This forum spotlights the Central Ohio Arts Impact Initiative and a growing movement to position the arts as essential to the region's social and economic infrastructure. This week, we hear from arts leaders, data experts, and civic partners on how creative work is delivering measurable outcomes that align with Central Ohio's priorities to nurture vibrant urban suburban, and exurban communities. Featuring: Dr. Kimberlee Goodman, Executive Director, The McConnell Arts Center Angela Meleca, Chief Advocate Officer, Meleca Creative Advisors Priscilla R. Tyson, Former Columbus City Councilmember, Founder, Priscilla Tyson Consulting Your host is Sheri Chaney Jones, Co-Founder and CEO, SureImpact. The presenting sponsor of the CMC livestream was The Center for Human Kindness at the Columbus Foundation. CMC's livestream partner was The Columbus Dispatch. This forum was also supported by Downtown Columbus, Inc. and The National Veterans Memorial and Museum. If you're ready to keep exploring this week's forum topic, our friends at The Columbus Metropolitan Library recommend reading "Run It Like a Business: Strategies for Arts Organizations to Increase Audiences, Remain Relevant, and Multiply Money – Without Losing the Art," by Aubrey Bergauer. This forum was recorded before a live audience at The National Veterans Memorial and Museum in Columbus, Ohio on December 3, 2025.

Post-Thanksgiving vibes in the bomb shelter! Dan and Frank swap holiday stories (Easton–P'burg memories and a new family baby on the way), then crank up the Hot Stove: the Mets' infield shuffle (Simeon for Nimmo talk), what it could mean for Tucker/Bellinger/Realmuto targets, plus the Phillies' quiet start.College football hits Rivalry Week: Texas–A&M, conference title games on deck, and who's really got a path in the new 12-team playoff.Then a full NFL Week 12 whiparound:Chiefs 23, Colts 20 (OT): KC escapes to keep the playoff door cracked.Bears 31, Steelers 28: Chicago steals one; NFC North stays spicy.Patriots 26, Bengals 20: Drake May keeps stacking wins.Ravens 23, Jets 10; Seahawks 27, Titans 24; Packers 27, Vikings 13Lions 34, Giants 27: Jamir Gibbs goes video-game mode late.Jaguars 27, Cardinals 24; Browns 24, Raiders 10; Falcons 24, Saints 10Rams 34, Bucs 7: LA looks hotter by the week.49ers 20, Panthers 9: Turnovers galore, CMC cleans it up.Cowboys 24, Eagles 21: Down 21–0, Dallas storms back—Pickens shines, Dak cooks.Plus: pick standings, lone-wolf chaos, and the Survivor Pool down to three (could this be the week it ends?).Special Thanks to:Fox Brothers Alarms - https://foxbrothersalarms.com First Baptist church of Phillipsburg NJ http://www.fbcpburg.org/

The 49ers (8-4) head into Week 13 looking for their third straight win against a tough Browns (3-8) defense. San Francisco's defense is playing its best football of the season, forcing five turnovers in the last two games and showing major improvement in coverage and tackling.The matchup centers on the quarterbacks. Shedeur Sanders flashed in his debut but still struggled with accuracy and rhythm. With a weak run game and unreliable receivers, the 49ers can force him into mistakes if they stay disciplined.Brock Purdy must rebound after a three-INT performance and now faces the NFL's No. 2 pass defense, led by Myles Garrett, who's chasing the sack record. Cleveland allows just 132 passing yards per game at home, so the 49ers will need to lean on CMC, George Kittle, and Jauan Jennings in the short game to take advantage of the Browns' tackling issues and slow down their pass rush.Visit Sports Spyder for up to date 49ers content:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://sportspyder.com/nfl/san-francisco-49ers/news⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow us on Twitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ @49ers_Access⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow us on Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ @49ers.Access⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠SeatGeek:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ “49ERSACCESS” for $20 off your first purchase!

The 49ers are entrenched in the final NFC playoff spot as they prepare to face the Cleveland Browns. However, with low temperatures, high-winds, and possible perception forecast for Sunday's matchup, holding onto that precious wild card spot might be more complicated. Having lost their previous contest in Cleveland under similar conditions in 2023, San Francisco will be tasked with executing their offense more efficiently this time while mitigating current NFL sack leader Myles Garrett. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan discuss Brock Purdy's regression last week against the Panthers and how he and the 49ers' offense can minimize mistakes against familiar obstacles in inclement weather and a formidable pass-rush. Also, Matt and Jennifer provide injury updates, surprising takes on a San Francisco offensive line playing well under-the-radar and where the 49ers might look in the draft. They also praise the evolution of Christian McCaffrey's game during an incredible individual season.--(4:00) Purdy's attributes as a starter -- anticipation, decisiveness, accuracy - were absent on three INTs(9:00) This is the first time Purdy has dealt with significant in-season time off, and he's adjusting(11:00) Will precipitation ahead of the game in Cleveland play a role in the outcome?(18:00) 49ers Injury Updates (Bethune, Okuayinonu, Piñeiro out)(22:00) Myles Garrett will be a handful for Trent Williams and offensive line(24:00) Matt believes the 49ers' OL starters this year might not change next year given their performance(32:00) CMC leads the league in rushing attempts and receptions, and is San Francisco's MVP Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Welcome to the Paint The Medical Picture Podcast, created and hosted by Sonal Patel, BA, CPMA, CPC, CMC, ICD-10-CM.Thanks to all of you for making this a Top 15 Medical Billing & Coding Podcast for 5 years on Feedspot.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sonal's 16th Season starts up and Episode 13 features Newsworthy updates on the month's fraud, waste, and abuse cases. Sonal's Trusty Tip and compliance recommendations focus on a Medicare telehealth update.Spark inspires us all to reflect on resilience based on the inspirational words of Dalai Lama.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Paint The Medical Picture Podcast now on:Spotify:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://open.spotify.com/show/6hcJAHHrqNLo9UmKtqRP3X⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Apple Podcasts: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://podcasts.apple.com/us/podcast/paint-the-medical-picture-podcast/id153044217⁠7⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Amazon Music: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://music.amazon.com/podcasts/bc6146d7-3d30-4b73-ae7f-d77d6046fe6a/paint-the-medical-picture-podcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Find Paint The Medical Picture Podcast on YouTube:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UCzNUxmYdIU_U8I5hP91Kk7A⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Find Sonal on LinkedIn:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/sonapate/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠And checkout the website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://paintthemedicalpicturepodcast.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠If you'd like to be a sponsor of the Paint The Medical Picture Podcast series, please contact Sonal directly for pricing: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠PaintTheMedicalPicturePodcast@gmail.com

From pandemic-speed vaccine deployment to AI-powered process control, what separates hype from real manufacturing transformation?The biotech industry faces a fundamental challenge: how do you maintain rigorous quality standards while accelerating development timelines, personalizing therapies, and adopting transformative technologies? The answer isn't found in chasing every innovation trend, it's in understanding which changes create genuine value and when to implement them across the product lifecycle.Irina Ramos brings a perspective earned through high-stakes execution. After leading the global technology transfer of AstraZeneca's COVID-19 vaccine, a project that compressed typical timelines while maintaining uncompromising quality standards, she's applying those lessons to the industry's next wave of challenges: phase-appropriate CMC strategy, the practical realities of AI integration, and building teams that bridge generational experience gaps in an era of rapid technological change.This conversation cuts through the noise. Irina discusses when continuous processing actually makes strategic sense (hint: it's not always the right answer), why AI in bioprocessing requires more human expertise rather than less, and the collaborative frameworks that enabled one of the fastest vaccine rollouts in history—lessons directly applicable to your current CMC challenges.Episode highlights:How the biotech community is constantly changing, and the importance of adaptability for future scientists (00:00)Navigating phase-appropriate CMC strategy: What to focus on in early clinical phases and which decisions set the foundation for compliance (02:36)Scenarios for switching from batch to continuous processing, including barriers and benefits for early-stage vs. established products (02:58)Lessons from leading AstraZeneca's COVID-19 vaccine technology transfer: Collaboration, rapid regulatory communication, and mission-driven teams (05:20)Adapting lessons from the pandemic for ongoing drug development—balancing speed and risk while maintaining quality (08:24)Realistic perspectives on integrating AI in bioprocessing: demystifying its applications, emphasizing human-critical oversight, and practical use cases in manufacturing (10:40)Key skills for scientists in a biotech world shaped by AI—why foundational understanding and strong mentorship matter (13:51)Bridging experience gaps: How to foster collaboration and creativity between new and established professionals in regulated environments (15:45)Final takeaway: Start small, remain mission-driven, and remember that one size does not fit all in continuous manufacturing (17:15)Whether you're evaluating process platform decisions for Phase I programs, building cross-functional teams for tech transfer, or determining which digital tools deserve investment beyond the buzzword, this episode provides decision frameworks grounded in real-world execution at global scale.Connect with Irina Ramos:LinkedIn: www.linkedin.com/in/irinaramosNext step:Need fast CMC guidance? New on-demand CMC advisory: Get 20 expert answers/month in 1 day + monthly strategy call. → Learn more: https://stan.store/SmartBiotech/p/ondemand-cmc-expertise-for-biotech-foundersBook a 20-minute call to help you get s

Alice Liu is the Research Lead at CoinMarketCap, leveraging CMC's data and collaborating with industry leaders to bring unique insight to millions of users. Her work covers market events, innovation analysis, and trending narratives across the entire crypto sector. Prior to joining CMC, Alice worked as an investment professional at WisdomeTree, Coutts, and J.P.Morgan. In this conversation, we discuss:- What happened on the 10/10 market crash - Current market sentiment - Liquidity is drying up - Are we in a bear market? - Privacy coins - The market is starved of narratives, hence why privacy took up - CMC20 Index - CMC Fear & Greed Index hit record low of 10 on Nov 22; has since rebounded to 15, consistent with past V-shape recoveries - Lista DAO - Watching onchain capital flow and whales - Total crypto market cap dropped below $3T — lowest since May, but signs show the worst is likely over CoinMarketCapX: @CoinMarketCapWebsite: coinmarketcap.comLinkedIn: CoinMarketCapAlice LiuX: @AliceCrypto3LinkedIn: Alice L.---------------------------------------------------------------------------------This episode is brought to you by PrimeXBT.PrimeXBT offers a robust trading system for both beginners and professional traders that demand highly reliable market data and performance. Traders of all experience levels can easily design and customize layouts and widgets to best fit their trading style. PrimeXBT is always offering innovative products and professional trading conditions to all customers.  PrimeXBT is running an exclusive promotion for listeners of the podcast. After making your first deposit, 50% of that first deposit will be credited to your account as a bonus that can be used as additional collateral to open positions. Code: CRYPTONEWS50 This promotion is available for a month after activation. Click the link below: PrimeXBT x CRYPTONEWS50FollowApple PodcastsSpotifyAmazon MusicRSS FeedSee All

In this episode of Smart Energy Voices, we bring you a conversation from SED Forum Fall featuring Chris Pennington of Iron Mountain and Brett Thompson of CMC and moderated by Debra Chanil, Editorial & Research Director at Smart Energy Decisions. They explore a major shift underway in energy strategy, moving from a focus on procurement to optimizing how and when energy is used. As renewable generation grows, aligning consumption with clean energy availability is becoming increasingly important. Pennington shares how data centers are integrating on-site storage and hourly matching to enhance flexibility, while Thompson explains how CMC manages electric arc furnace operations and demand response participation to support grid reliability. Together, they highlight the growing need for flexible load strategies, stronger utility partnerships, and forward-looking planning in the ever-changing energy landscape. You will want to hear this episode if you are interested in… Why energy strategy is shifting from procurement to optimized usage (03:40) Changing grid dynamics and shifting peak pricing periods (07:39) Demand response and managing load peaks (14:20) Where energy customers should focus next (15:47) Policy and regulatory challenges (16:48) How data centers are affecting grid capacity and costs (18:18) The future of clean energy (20:24) For full episode show notes, click here. Connect with Chris Pennington On LinkedIn Chris Pennington is Director of Energy & Sustainability for Iron Mountain Data Centers. His responsibilities include the development of Iron Mountain's global sustainability program and identification of opportunities to innovate for a more sustainable digital future. He received the Green Power Leader of the Year award in 2021 from the Center for Resource Solutions and championed Iron Mountain's public commitment to 24/7 carbon free energy that same year. Chris actively participates in the Clean Energy Buyers Association as faculty for their energy buyer support programs, as well as Eurelectric's 24/7 carbon free energy hub. Connect With Smart Energy Decisions Smart Energy Decisions Follow us on LinkedIn Subscribe to Smart Energy Voices on Apple Podcasts, Google Podcasts, Android, Spotify, Stitcher, TuneIn Radio, aCast, PlayerFM, iHeart Radio If you're interested in participating in the next Smart Energy Decision Event, visit smartenergydecisions.com or email our Community Development team at attend@smartenergydecisions.com

Kaan Özaydın ve Akın Türkmen... Cleveland Browns'ta galibiyet ile başlayan Shedeur Sanders dönemi, Shedeur Sanders'a bile yenilen Las Vegas Raiders'ın hücum koçu Chip Kelly'i kovup üçüncü defa Greg Olson'ı hücumun başına geçirmesi, Brock Purdy'nin interception'larına rağmen kazanan San Francisco 49ers, CMC'nin muhteşem performansı... Ezeli rakibi ve son şampiyon Philadelphia Eagles'a ağır bir darbe indiren Dallas Cowboys, Lamar Jackson'ın zayıf performanslarına rağmen kazanan Ravens, Seahawks'ın seviye atlayan WR'ı Jaxon Smith-Njigba, Vikings'in bitmek bilmeyen J.J. McCarthy problemi, Buffalo Bills'te Josh Allen'ın şaşırtan kötü performansı ve dahası...

Kathryn Golden didn't set out to be a scientist. In fact, she made her parents promise she wouldn't have to become one when she enrolled at a science-focused high school. But a chemistry class changed everything, setting her on a path from MIT's bioprocessing labs to senior leadership roles in Biotech and pharma.  Now VP of Technical Operations at Ottimo Pharma and co-founder of Sunflower Therapeutics, Kathryn's career has been shaped by a relentless curiosity, a deep commitment to patient access, and a willingness to step into the unknown. She shares her journey from building perfusion bioreactors in grad school, to leading global CMC teams, to launching portable manufacturing units for biologics in the developing world.  In this conversation, Kathryn reflects on lessons in leadership, mentorship, and integrity - from creating a calm, learning-focused culture to knowing when to walk away. She talks openly about imposter syndrome, what it really takes to transition into executive roles, and how entrepreneurship, like science, is best approached as an experiment. 

Today, I'm joined by Todd Meleney, co-founder & CEO of While on Earth. An athletic footwear and apparel brand for the modern wellness consumer, While on Earth prioritizes versatile "performance wellness" over single-sport specialization. In this episode, we discuss creating an underdog brand in a competitive market.  We also cover: Christian McCaffrey's role as co-founder  Defining "performance wellness" as a category Investing in grassroots community over paid marketing    Subscribe to the podcast → insider.fitt.co/podcast   Subscribe to our newsletter → insider.fitt.co/subscribe   Follow us on LinkedIn → linkedin.com/company/fittinsider    While On Earth's Website: www.whileonearth.co  While On Earth's IG: https://www.instagram.com/whileonearth/  - The Fitt Insider Podcast is brought to you by EGYM. Visit EGYM.com to learn more about its smart fitness ecosystem for fitness and health facilities. Fitt Talent: https://talent.fitt.co/  Consulting: https://consulting.fitt.co/  Investments: https://capital.fitt.co/   Chapters:  (00:00) Introduction (01:40) Todd's background and While on Earth overview  (02:40) White space opportunity in performance footwear  (04:25) Lessons from building NOBULL  (05:15) Shifting consumer behavior toward holistic wellness  (07:15) Defining "performance wellness" as a category  (09:30) Product philosophy (12:00) Building vs. buying brand awareness  (14:30) Grassroots community strategy over paid marketing  (17:00) Retail strategy (19:30) Athlete partnerships (22:00) Christian McCaffrey as co-founder and investor  (24:30) Product roadmap and innovation focus  (27:00) Staying authentic while scaling (29:05) Running category launch in 2026 (30:15) CMC signature product line coming 2026  (32:45) Role of athletes in brand building (34:50) Conclusion

The San Francisco 49ers beat the Carolina Panthers 20-9 in Week 12, holding their ground in the NFC Playoff Race despite a rough night from Brock Purdy.Purdy threw 3 INTs (almost 5), but the 49ers defense bailed him out every time — led by Ji'Ayir Brown's two game-changing interceptions, including one in the end zone on 1st-and-Goal. Christian McCaffrey carried the offense with his 8th game of 50+ rushing and 50+ receiving yards, a TD, and nine touches on the opening 15-play drive. Jauan Jennings fought through three tackles for a tough TD, and Clelin Ferrell delivered a huge sack as the Panthers tried to rally.It wasn't pretty, but the 49ers controlled the clock, leaned on CMC, and made the clutch plays to escape with a must-have win.Can San Francisco keep climbing the NFC standings? Let's break it all downVisit Sports Spyder for up to date 49ers content:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://sportspyder.com/nfl/san-francisco-49ers/news⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow us on Twitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ @49ers_Access⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow us on Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ @49ers.Access⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠SeatGeek:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ “49ERSACCESS” for $20 off your first purchase!

The biotech industry operates under constant tension: we work with products that directly impact human lives, demanding rigorous controls and validation at every step. Yet standing still means falling behind. The question isn't whether to innovate, it's how to do it without compromising the quality and safety standards that define our industry.Irina Ramos has lived this paradox throughout her career. As a downstream processing leader who's guided CMC programs from early development through global regulatory filings, she helped orchestrate the worldwide transfer of AstraZeneca's COVID-19 vaccine—a masterclass in balancing speed, scale, and uncompromising quality standards. Now, she's championing a vision that sounds almost radical: lights-out biomanufacturing facilities where continuous processes run at steady state with minimal human intervention.In this conversation, Irina shares the unfiltered reality of building innovation cultures in conservative environments, the surprising drivers behind continuous processing adoption, and why the industry's careful nature isn't a barrier to transformation. It's the foundation for sustainable innovation.Discussion highlights:Why conservatism is vital in biotech—and how to balance it with innovation (00:00)The vision for "lights-out" manufacturing and if bioprocess facilities could run with minimal human intervention (02:50)Irina Ramos's career story and the lessons her "happy accidents" teach junior scientists (03:53)Mindset shifts: Transitioning from scientist to innovation leader in CMC development (06:29)Building an innovation culture in a conservative, highly regulated industry (08:07)Essential mindsets for scientists to thrive and innovate in biotech environments (11:22)Coordination strategies for effective communication across stakeholders, departments, and geographies (13:52)The misconceptions of continuous manufacturing and what actually drives its adoption (17:09)What's hot in continuous biomanufacturing: trends, global perspectives, and how real-time analytics can change process control (21:12)Guiding principles for choosing between hybrid or end-to-end continuous processes (23:46)Practical tips on implementing control strategies and real-time monitoring in manufacturing (25:01)If you're navigating the shift from batch to continuous processing, leading cross-functional innovation initiatives, or wondering how to advocate for new technologies without disrupting validated processes, this episode offers practical frameworks you can apply immediately.Connect with Irina Ramos:LinkedIn: www.linkedin.com/in/irinaramosNext step:Need fast CMC guidance? New on-demand CMC advisory: Get 20 expert answers/month in 1 day + monthly strategy call. → Learn more: https://stan.store/SmartBiotech/p/ondemand-cmc-expertise-for-biotech-foundersBook a 20-minute call to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/call

On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan reflect on the blockbuster trade that brought Christian McCaffrey to San Francisco ahead of Monday night's matchup against his former team.  Additionally, Matt and Jennifer discuss how a healthy 49ers offense will improve their run game. Matt then sits down with defensive back Deommodore Lenoir to discuss his growth as a leader and team captain of the 49ers' defense.--(1:53) Matt, JLC reflect on 49ers' trade that brought Christian McCaffrey to San Francisco(6:12) Matt discusses how CMC has blossomed into face of the 49ers' offense and playing at an all-time level(12:56) Matt, JLC discuss how a healthy 49ers offense will improve CMC's running game(17:08) Matt, JLC debate if matchup vs. Panthers is a must-win game(25:00) Deommodore Lenoir discusses what it means to him to be a captain on the 49ers, and finding his voice, role as a leader(29:05) Lenoir talks how Richard Sherman took notice of his potential as a young player(37:55) Matt, JLC discuss if  Lenoir get enough attention for his playmaking(42:20) Matt wants to see rookie LB Nick Martin on the field as a pass rusher  Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Dirty Work Hour 1: 49ers/Panthers preview, Matchups vs Rico Dowdle, T-Mac and Bryce Young, CMC vs his old teamSee omnystudio.com/listener for privacy information.

In the third hour, Mac & Bone turn their attention to the 49ers, to talk about facing CMC for the first time since the trade, they discuss the problems he'll cause, and if this is a revenge game for CMC, they open the phones to hear from Hornets fans on the LaMelo trade rumors, & they preview the Duke/UNC football game See omnystudio.com/listener for privacy information.

Dirty Work Hour 1: 49ers/Panthers preview, Matchups vs Rico Dowdle, T-Mac and Bryce Young, CMC vs his old teamSee omnystudio.com/listener for privacy information.

What if you could analyze every metabolite, glycan variant, and unknown impurity in your bioprocess sample—not just the targets you're looking for, but everything that's actually there? Cryogenic infrared ion spectroscopy combined (CIRIS) with AI-powered analysis transforms untargeted screening from aspiration to reality.This episode moves from fundamental principles to practical applications. While Part 1 established how CIRIS overcomes mass spectrometry's structural limitations, Part 2 reveals what becomes possible when you can definitively identify complex mixtures: better mAb characterization, earlier disease detection, and process decisions based on complete data rather than educated guesses.Professor Tom Rizzo returns to discuss Isospec Analytics' path from laboratory innovation to commercial service platform. His transition from academic leadership at EPFL to biotech entrepreneurship offers insights for any scientist considering whether breakthrough research deserves a startup—and what that journey actually requires.For bioprocess scientists drowning in unidentified peaks, struggling with glycan heterogeneity, or making critical manufacturing decisions with incomplete analytical data, this conversation demonstrates how next-generation analytics powered by quantum chemistry and machine learning can illuminate what's been hidden in your samples all along.Episode Highlights:Why targeted metabolomics creates a "streetlight effect"—and how untargeted CIRIS analysis reveals the complete molecular landscape (00:00)Isomer-specific glycan characterization for mAbs: distinguishing structural variants that impact efficacy and immunogenicity (03:17)Advanced disease detection and biomarker discovery: identifying diagnostic signatures in complex biological matrices (05:21)AI meets quantum chemistry: automated spectral library building and machine learning algorithms that accelerate molecule identification from hours to seconds (06:05)From data generation to decision-making: how comprehensive analytics and AI transform bioprocess development workflows (09:23)Isospec's commercial roadmap: service platform for comprehensive sample analysis and projected timeline for benchtop instrumentation (10:09)Academic to entrepreneur: Tom Rizzo's perspective on leaving tenure for a startup, with practical advice for scientists evaluating the leap (12:05)Personal motivation behind early diagnostics: cancer and leukemia experiences that drive Isospec's clinical applications (14:11)Technical deep dive: messenger tagging methodology and achieving single-ion infrared detection sensitivity (15:41)The transformative capability: adding a structural dimension to mass spec data that eliminates ambiguity in complex mixture analysis (17:55)Mass spectrometry tells you what masses are present. Cryogenic infrared ion spectroscopy tells you what molecules they actually are. When coupled with AI-powered analysis, this combination enables truly comprehensive characterization—from process impurity identification to critical quality attribute assessment to early disease biomarker discovery.If you're making bioprocess decisions with incomplete analytical information, managing glycan complexity in biologics development, or exploring how emerging analytical technologies could solve your toughest characterization challenges, this episode provides both the technical foundation and the commercial pathway forward.

Welcome to the Paint The Medical Picture Podcast, created and hosted by Sonal Patel, CPMA, CPC, CMC, ICD-10-CM.Thanks to all of you for making this a Top 15 Medical Billing & Coding Podcast for 5 Years on Feedspot. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sonal's 16th Season starts up and Episode 12 features a Newsworthy update on RAC audits for 2025.Sonal's Trusty Tip and compliance recommendations focus on specific RAC audits for 2025.Spark inspires us all to reflect on resilience based on the inspirational words of Isabel Allende.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Paint The Medical Picture Podcast now on:Spotify: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://open.spotify.com/show/6hcJAHHrqNLo9UmKtqRP3X⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Apple Podcasts: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://podcasts.apple.com/us/podcast/paint-the-medical-picture-podcast/id153044217⁠7⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Amazon Music: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://music.amazon.com/podcasts/bc6146d7-3d30-4b73-ae7f-d77d6046fe6a/paint-the-medical-picture-podcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Find Paint The Medical Picture Podcast on YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UCzNUxmYdIU_U8I5hP91Kk7A⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Find Sonal on LinkedIn:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/sonapate/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠And checkout the website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://paintthemedicalpicturepodcast.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠If you'd like to be a sponsor of the Paint The Medical Picture Podcast series, please contact Sonal directly for pricing: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠PaintTheMedicalPicturePodcast@gmail.com⁠⁠

1:55: The opening statement of Christian McCaffrey's MVP case:11:24: The 49ers win 75 PERCENT of the time with McCaffrey in the lineup12:26: Rant: How does Kyle Shanahan still not understand that the 49ers are “totally f—ked” without CMC? — Get him off the field in blowouts18:10: McCaffrey is even more valuable than Kyle21:13: Somehow, Shedeur Sanders' nightmare debut got even worse after the game37:21: Draymond Green's big mistake after the Angel Reese chant:47:51: Today in history: Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Brock Purdy's return sparked the 49ers' offense, it also brought a much needed divisional win in a blowout against the Cardinals. Purdy threw for three touchdowns on Sunday, two of which went to a favorite target in tight end George Kittle and the other went to offensive fulcrum Christian McCaffrey, who leads the NFL in scrimmage yards this season through Week 11. Skyy Moore set the tone, returning the opening kickoff 98 yards to the 1-yard line, setting up a McCaffrey 1-yard touchdown run. San Francisco maintained control throughout the game, one in which Arizona did itself no favors accumulating a franchise-record 17 penalties. San Francisco did not escape Arizona unscathed though, as kicker Eddy Piñeiro suffered a hamstring injury in the third quarter that could force the team to bring in a new kicker. On this episode of '49ers Talk,' co-hosts Matt Maiocco and Jennifer Lee Chan break down San Francisco's outstanding performance against the Cardinals Sunday at State Farm Stadium. Matt and Jennifer discuss the impact of Purdy's return on the 49ers' offense during a crucial stretch, Kittle and CMC's dominance, and how injuries to both Piñeiro and linebacker Tatum Bethune might affect the team ahead of Monday's showdown with the Carolina Panthers.--(0:00) 49ers did what they had to do to get win vs. Cardinals(3:00) Will the 49ers have to add a kicker because of Eddy Piñeiro's injury?(4:00) Brock Purdy's return dispels any QB controversy from media(12:00) Can CMC achieve 1,000-1,000 season?(14:00) This is the healthiest the 49ers have been on offense all season(17:30) The 49ers' defense forced three takeaways(25:00) What type of team are the 49ers? Can they bring this type of performance on MNF?(28:00) Robert Saleh will really have to earn his money down the stretch this season(30:00) Looking ahead, the 49ers need beat NFC playoff contenders Carolina, Chicago Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The San Francisco 49ers dominated the Cardinals 41-22 in Week 11 behind a huge day from Brock Purdy, Christian McCaffrey, and George Kittle. Purdy returned to the lineup with 3 touchdowns, including two to Kittle and one to CMC, as Kyle Shanahan kept the offense aggressive all game long.Special teams set the tone early with Skyy Moore's 98-yard kickoff return, leading to a quick McCaffrey TD. CMC finished with 3 total touchdowns, 121 scrimmage yards, and his first 20+ yard run of the season. Kittle added 6 catches, 67 yards, and 2 scores in another dominant outing.The 49ers defense delivered 3 takeaways (INTs by Lenoir and Mustapha, a goal-line FF by Upton Stout) and made key stops despite coverage issues and a quiet pass rush. Arizona hurt themselves with 17 penalties for 130 yards, while San Francisco committed just one.Visit Sports Spyder for up to date 49ers content:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://sportspyder.com/nfl/san-francisco-49ers/news⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow us on Twitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ @49ers_Access⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow us on Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ @49ers.Access⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠SeatGeek:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ “49ERSACCESS” for $20 off your first purchase!#49ers #Cardinals #NFLWeek11 #SanFrancisco49ers #ArizonaCardinals

HOST: Mark Longo, The Options Insider CO-HOST: Mike Tosaw, St. Charles Wealth Management CO-HOST: Andrew Giovinazzi, The Option Pit In this episode, the panel discusses the current state of the options market. They also look at unusual options activity in CMC and QGEN. Uncle Mike Tosaw provides a Strategy Block focusing on the importance of responsible options trading and knowing when to exit a position. Market conditions, including significant whipsaw action in the S&P 500 and notable upcoming earnings reports from major retailers like Home Depot, Lowe's, and Target, are analyzed. The episode concludes with insights on what the hosts are watching in the market for the upcoming week.

JMToWin from One Week Season walks us through the Week 11 DFS slate from a GPP perspective, shares his top plays at each position, and then builds a DraftKings lineup using some of his favorite building blocks. In the second half, Youdacao from Run The Sims join to discuss sneaky stacks for Week 11 tournaments and input volatility.

In this episode of Molecule to Market, your host Raman Sehgal discusses the pharmaceutical and biotechnology supply chain with Jean-François Brepson, Chief Executive Officer at PathoQuest. The conversation covers: Navigating 20 years of global leadership roles at Ipsen before moving from the corporate world into an investor-led entrepreneurial adventure The tough decision to refocus PathoQuest from diagnostics into a pure play CRO and pharma services business How a major strategic partnership transformed the company's trajectory and why Jean sees partnerships as a competitive weapon Riding the tailwind of the FDA's move away from animal testing and offering something game-changing in the CMC and GMP space The opportunities ahead for CROs and CDMOs in helping unlock the next wave of innovation Jean-François Brepson is a dedicated leader with deep experience in biotechnology and pharmaceuticals. Since becoming CEO of PathoQuest in 2015, he has built the company into a leading global CRO specializing in quality control of biological drugs using Next Generation Sequencing (NGS). Over his career, he has advanced innovative technologies and solutions that bridge scientific progress with real-world application. Prior to joining PathoQuest, Jean was Senior Vice President at Ipsen, where he led the global GI-Oncology and Endocrinology franchise.   Molecule to Market is sponsored by Bora Pharma, Charles River, and Lead Candidate. Please subscribe, tell your industry colleagues, and help us celebrate the value of the global life science outsourcing space. We'd also appreciate a positive rating!