Podcasts about CMC

JMToWin from One Week Season walks us through the Week 9 DFS slate from a GPP perspective, shares his top plays at each position, and then builds a DraftKings lineup using some of his favorite building blocks. In the second half, Youdacao from Run The Sims join to discuss sneaky stacks for Week 9 tournaments and input volatility.

Welcome to the Paint The Medical Picture Podcast, created and hosted by Sonal Patel, BA, CPMA, CPC, CMC, ICD-10-CM.Thanks to all of you for making this a Top 15 Podcast for 5 Years: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://blog.feedspot.com/medical_billing_and_coding_podcasts/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sonal's 16th Season starts up and Episode 9 features Newsworthy updates on the month's fraud, waste, and abuse cases. Sonal's Trusty Tip and compliance recommendations focus on diagnosis coding for family history of breast cancer.Spark inspires us all to reflect on resilience based on the inspirational words of Maya Angelou.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Paint The Medical Picture Podcast now on:Spotify:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://open.spotify.com/show/6hcJAHHrqNLo9UmKtqRP3X⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Apple Podcasts: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://podcasts.apple.com/us/podcast/paint-the-medical-picture-podcast/id153044217⁠7⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Amazon Music: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://music.amazon.com/podcasts/bc6146d7-3d30-4b73-ae7f-d77d6046fe6a/paint-the-medical-picture-podcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Find Paint The Medical Picture Podcast on YouTube:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UCzNUxmYdIU_U8I5hP91Kk7A⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Find Sonal on LinkedIn:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/sonapate/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠And checkout the website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://paintthemedicalpicturepodcast.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠If you'd like to be a sponsor of the Paint The Medical Picture Podcast series, please contact Sonal directly for pricing: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠PaintTheMedicalPicturePodcast@gmail.com

From October 20-23, the Central Committee of the Chinese Communist Party held its Fourth Plenum in Beijing, marking an important moment as the Party sets the direction for China's development for the next five years. The session adopted recommendations for the 15th Five-Year Plan, endorsing Xi Jinping's goals of high-quality development, scientific and technological self-reliance, and strengthening national security in response to rising global instabilities. The Central Committee also announced the replacement of 11 members, the highest personnel turnover since 2017 amid an ongoing anti-corruption purge in the military. To discuss the plenum's outcomes, we are joined by Jonathan Czin. Jonathan is a leading expert on Chinese politics and foreign policy. He holds the Michael H. Armacost Chair in Foreign Policy Studies and is a fellow in the John L. Thornton China Center at the Brookings Institution. He previously led the intelligence community's analysis of Chinese politics and policy making at the CIA and also spent two years as director for China at the National Security Council during the Biden administration.  Timestamps:  [00:00] Start  [01:36] Why the Fourth Plenum Matters  [03:37] Key Takeaways: Policy Continuity and Political Purges  [05:07] Zhang Shengmin and Xi Jinping's Military Ambitions  [09:23] Signals and Adjustments in Economic Planning  [11:56] Previewing the 15th Five-Year Plan  [13:33] Xi Jinping's Growing Confidence  [17:42] Political Messaging and Choreography  [20:21] Language in the Communique: “Strategic Resolve”  [22:28] What to Expect from the Xi-Trump Summit  [26:38] Is Beijing Worried the Summit Could Backfire? 

FOLLOW UP: IMPACT OF JLR SHUTDOWNProfessor David Bailey has written up a piece on Blogs from the Blackstuff following a report from the Cyber Monitoring Centre (CMC), which outlines the cost of the JLR shutdown and it is large. The estimated cost is in the region of £1.9 billion but could be as high as £2.1 billion. Over 5,000 businesses were affected. The CMC hopes businesses, the Government and insurers to learn lessons. To read more, click this article link here. NEW CHIP CRISIS LOOMINGAnother week and another example of how crucial China is to making things. This time there is a spat between Dutch and the Chinese Governments over the chip maker Nexperia after the Chinese CEO was removed and the European country took control of the company. They supply a lot of the car industry, particularly the electric car making segment. China has restricted exports of their chips, which means the company cannot guarantee reliable supply. For more on this story, click this link to an electrive article here. PORSCHE PROFITS PLUMMET AGAINPorsche has released their financial results for the last quarter and they are, once again, poor. They had an operating loss of €966 million, with return on sales for the year dropping to just 0.2% after being 14.1% the year before. Click this Piston Heads article link here, for more. FORD EUROPE FINDS A NEW BOSSFord Europe are to get a new president, Jim Baumbick, who moves from global head of product development and head of advanced product development. He takes the reigns on 1 November 2025. The role has been vacant for some time. If you want to read more, click this electrive article link here. UK GOVERNMENT HELP TOYOTA BUILD A CARToyota is receiving £15 million investment from the UK Government to explore the feasibility of bringing their FT-Me Concept to market. Think IQ size and it being a quadracycle, with the idea of it being used in high density urban areas. You can find out more, by clicking this Autocar article link here. WAYMO SELF-DRIVING CARS TO TEST IN LONDONWaymo is bringing some of their autonomous vehicles to London, to take part in a Government backed trial. They will join Uber, in the spring. For more on this story, click this Autocar link. For some context, here is a link to a Bluesky thread that demonstrates had bad Waymo is at autonomous driving (and it is the least worst at it!). LORDS PUSH FOR ACCESSIBILITY AT EV CHARGERSThe House of Lords has backed an amendment to the Planning and Infrastructure Bill, that would make accessibility standards legally binding for EV chargers if approved in the House of Commons. Click this link from EV Powered to read more. If you like what we do, on this show, and think it...

Unity at the Tower of Babel was to make a name for man; in Messiah, unity makes His Name known. Listen to Rabbi David's Shabbat sermon based out of Parasha Noach at CMC.

Your process works perfectly at two-liter bench scale. Then you hit fifty liters and titer drops 20%. By two hundred liters, aggregation appears and charge variants shift. Your management team asks: "How long to fix this?" The honest answer? Three to twelve month, because you're flying blind.In Part 2 of this Quality by Design Master Class, David Brühlmann reveals why scale-up chaos isn't inevitable. It's a solvable engineering problem. Drawing on experience leading bioprocess innovation at Merck and guiding biotech companies through CMC development, David delivers the process control framework that transforms reactive troubleshooting into predictive manufacturing.The core truth: eighty percent of quality problems stem from twenty percent of your process variables. David shows how to identify Critical Process Parameters, implement intelligent control strategies, and leverage hybrid modeling that reduces experiments by 60-80%. With case studies from Genentech and Amgen, you'll gain the blueprint that turns QbD requirements into competitive advantage.Part 1 taught you what to build and measure. Part 2 shows you how to control your process to consistently deliver commercial-scale quality.Topics Discussed:The common pitfalls of scaling up manufacturing from bench to production, and why process control must go beyond end-product testing (02:10)Overview of the QbD framework: Quality Target Product Profile (QTPP), Critical Quality Attributes (CQAs), and the focus of this episode - Control Strategies for manufacturing (05:00)Identifying and monitoring Critical Process Parameters (CPPs) and their impact on quality, with real-world examples from Genentech's monoclonal antibody platform (08:20)Structure of an effective manufacturing control strategy: Input, process, and output controls - including practical details on real-time monitoring and release testing (11:00)The role of hybrid modeling and machine learning in accelerating process optimization, and how this approach can dramatically reduce the experimental burden (13:30)Real examples of improved outcomes and efficiency through model-based control strategies, and why training and process understanding are essential for team success (16:10)A quick, actionable exercise biotech teams can use to map process risks and identify critical control points (16:55)Whether you're part of a start-up or a large biotech firm, this episode offers clear, strategic steps for implementing QbD and improving process reliability. Don't forget to listen to Part 1 for more on QTPP and CQA, and visit www.bruehlmann-consulting.com for additional resources.Next step:Book a 20-minute call to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/callPreparing for your IND? We're building a CMC Dashboard in Excel to help biotech founders track tasks, timelines, and risks in one place. Join the waitlist for early access at https://scale-your-impact.notion.site/27dd9c6ba679804b80a7ce439d56c91a?pvs=105

2:25: Dramyond on Jimmy and alphas:7:30: The No. 1 alpha dog in the Bay Area right now? CMC. But how about George Kittle, too?9:04: Steph is the best Warrior ever — but really isn't an alpha dog18:10: The Giants have a new manager, and it's a first. So, good luck, Buster, because your reputation rests on this.25:12: The flip-around rant:33:36: The NFL knew exactly what it was doing by choosing Bad Bunny for the Super Bowl Halftime Show:42:20: Today in history: Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Welcome to the Paint The Medical Picture Podcast, created and hosted by Sonal Patel, CPMA, CPC, CMC, ICD-10-CM.Thanks to all of you for making this a Top 15 Podcast for 5 Years: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://blog.feedspot.com/medical_billing_and_coding_podcasts/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sonal's 16th Season starts up and Episode 8 features a Newsworthy update on claims being held by Medicare.Sonal's Trusty Tip and compliance recommendations focus on percutaneous needle breast biopsies.Spark inspires us all to reflect on resilience based on the inspirational words of Marianne Williamson.Checkout the Workshop for Telehealth Playbook for 2025-2026 on: ⁠⁠⁠https://kwadvancedconsulting.com/training-education-2/on-demand-webinars/webinar-registration/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Paint The Medical Picture Podcast now on:Spotify: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://open.spotify.com/show/6hcJAHHrqNLo9UmKtqRP3X⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Apple Podcasts: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://podcasts.apple.com/us/podcast/paint-the-medical-picture-podcast/id153044217⁠7⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Amazon Music: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://music.amazon.com/podcasts/bc6146d7-3d30-4b73-ae7f-d77d6046fe6a/paint-the-medical-picture-podcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Find Paint The Medical Picture Podcast on YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UCzNUxmYdIU_U8I5hP91Kk7A⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Find Sonal on LinkedIn:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/sonapate/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠And checkout the website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://paintthemedicalpicturepodcast.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠If you'd like to be a sponsor of the Paint The Medical Picture Podcast series, please contact Sonal directly for pricing: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠PaintTheMedicalPicturePodcast@gmail.com⁠⁠⁠⁠⁠⁠

Get your Week 8 Fantasy Football edge! Keith Flemming and Kacey Kasem break down stats and trends to crush your Week 8 lineup decisions. Learn why this version of the Chiefs offense could be the best in the Mahomes Era, why D'Andre Swift might be a good candidate to sell now, how Jordan Addison is becoming one of the best WRs in fantasy, and more! (00:00) Intro (00:54) Chiefs Offense (03:45) Rashee Rice (05:12) Saquon Barkley (07:55) CMC(10:04) Colts Historic Offense (13:16) Bears Backfield (14:54) Patriots Passing Game (17:00) Broncos Record Setting Comeback Win (20:48) Best Waiver Wire Add for Week 8(23:07) Dolphins Run Defense (25:52) Jordan Addison #FantasyFootball #Football#NFL #NFLWeek8 #Week8 #FantasyFootballWeek8 #ChiefsKingdom #DallasCowboys #ForTheShoe

Want to stay up to date on LCMS Happenings from Pastor Tim?Join the LCMS Current: https://www.uniteleadership.org/thelcmscurrentThe LCMS is wrestling with a familiar question: are we keeping distinctions or breaking barriers?Pastor Tim Ahlman, Jack Kalleberg, and Pastor Jonathan Dinger return to one of Lead Time's most popular conversations—this time reframed around access.- What does it mean to create access to the Gospel without compromising theological depth?- How do local contexts—from Arizona to Idaho—shape the way churches live out the confessions?- And what happens when fear, control, or mistrust shape our leadership more than faith and freedom?

Baldy joins The Roast to talk about the loss on defense of Bryce Huff, plus the return of explosive CMC runs and if the 49rs can win the NFC West with Mac Jones under center

THANKS FOR WATCHING! DON'T FORGET TO SUBSCRIBE TO OUR CHANNEL Get in on the action with BETR Picks! Click our link: https://engagebetr.onelink.me/auSX/BENCHD Or use our CODE: “BENCHD” BETR will match 1st deposit up to $250!!! SPORTS JUST GOT BETR VISIT BENCHDSHOW.COM - Special Announcements - Fantasy Rankings and Tips - The BENCH'd Beat - Sign up for our weekly email ————— NFL Podcast | New Episodes 3x a week FOLLOW THE SHOW Instagram: https://www.instagram.com/benchdshow TikTok: https://www.tiktok.com/@benchdshow Twitter: https://twitter.com/benchdshow Spotify Podcasts: https://podcasters.spotify.com/pod/show/benchdshow Apple Podcasts:https: podcasts.apple.com/us/podcast/benchd-w-the-tovar-brothers-nfl/id1692285587 ————- SHOP FAT BROTHERS https://fatbrothersfoods.com?sca_ref=9522676.RQeKd6HiGTuw2 —————- SHOP AT: DAD GANG HATS https://www.dadgang.co USE CODE: BENCHD76826 ------------ 0:00 Intro 2:20 Happy Birthdays 4:56 BENCHIES 5:06 Matthew Stafford BALLIN 6:08 Mike Vrabel revenge game 6:52 Former Raiders HC Antonio Pierce 8:00 Brandon Aubrey breaker of records 8:46 Broncos vs Giants trash talk 10:15 Dolphins franchise meltdown 11:28 The Ass Class 18:35 Rams defeat Jaguars 19:39 Travis Hunter needs to stay WR 21:49 Bears defeat Saints 22:45 Bears heat check 23:29 Browns defeat Dolphins 25:11 Patriots defeat Titans 26:35 Is Cam Ward a bust? 28:11 Chiefs defeat Raiders 28:40 Chiefs are BACK 30:43 Eagles defeat Vikings 31:18 Jalen Hurts MVP? 37:19 Vikings heat check 39:17 Panthers defeat Jets 39:59 Aaron Glenn hot seat 40:54 Broncos defeat Giants 41:36 Broncos are massive frauds 47:52 Colts defeat Chargers 48:47 Chargers are the same old Chargers 53:40 Cowboys defeat Commanders 54:00 Commanders never had a shot 56:11 Cowboys offense is ELITE 58:01 Packers defeat Cardinals 58:27 Cardinal must move on from Kyler Murray 1:00:44 49ers defeat Cardinals 1:03:52 CMC won't last 1:06:42 Mailbag Monday Learn more about your ad choices. Visit megaphone.fm/adchoices

Are you avoiding foods just because you can’t pronounce an ingredient? You’re not alone — but this week, we unpack why obsessing over “seed oils” and additives can sometimes do more harm than good. In this episode, Leanne and Susie explain how to actually read a food label, which additives are worth caring about (and which aren’t), and the 10-year window when your health habits matter most. Inside this episode: Smart label reading: Why a long ingredient list doesn’t always mean “unhealthy,” how to judge the whole food, and what to focus on instead of fear-scrolling for “nasties.” The nuance on additives: The few ingredients dietitians really avoid — flavour enhancers 621/635, nitrates in processed meats (250 range), and certain emulsifiers like CMC, carrageenan, and polysorbate-80 — plus why dose and frequency matter more than perfection. Your 36–46 health wake-up call: New research shows this decade is when silent metabolic and hormonal shifts begin. Leanne and Susie share the simple screenings and habits that can genuinely protect your future health. Product spotlight: The protein pudding everyone’s talking about — how it stacks up nutritionally (hint: the calcium is impressive) and when it fits into a balanced diet. Listener question: “Do I really need protein powder?” The honest truth from two dietitians who own a supplement brand — and still say food first. Take-home tip: Stop aiming for perfection. Focus on patterns — not single ingredients. A balanced diet with mostly whole foods, enough protein, and regular movement will always matter more than avoiding a tiny emulsifier. Connect with us: Follow us on Instagram @the_nutrition_couch_podcast for more product reviews and label breakdowns, or submit your listener question for a future episode. We also mention our own supplement range, Designed by Dietitians, and acknowledge our role as founders when discussed.See omnystudio.com/listener for privacy information.

Over 40% of biotherapeutic failures during clinical development stem from stability problems—and most trace back to protein aggregation that could have been prevented. In this episode of the Smart Biotech Scientist Podcast, David Brühlmann exposes the hidden manufacturing crisis that derails promising biologics programs and delivers the systematic Quality by Design framework that elite biotech companies use to build quality into every process step.David brings two decades of bioprocess expertise from his time leading technology innovation at Merck and now guiding emerging biotech companies through CMC development as Managing Director of Brühlmann Consulting. Drawing on FDA and EMA regulatory guidance as well as landmark industry case studies he transforms complex QbD principles into an actionable roadmap for IND submission.This isn't theoretical regulatory compliance. It's competitive survival. Companies implementing these QbD foundations achieve predictable manufacturing scale-up, accelerated regulatory approval, and significant cost advantages. If your team is navigating CMC development for the first time or struggling with scale-up challenges, this episode provides the blueprint to transform process uncertainty into manufacturing confidence.What You'll Learn in This Episode:The high clinical failure rate for biologics due to protein aggregation and stability problems, and one company's costly lesson in the scale-up phase. (00:00)An introduction to Quality by Design (QbD)—how it differs from traditional development and why “the process is the product” in biologics. (03:09)The three foundational pillars of QbD, with today's focus on product understanding and quality requirements. (05:46)Constructing your Quality Target Product Profile (QTPP): what to include and why starting with the patient is key. (07:05)A real-world QTPP example—the AMAP case study—and how it shaped formulation, packaging, and critical quality standards. (09:45)Defining and prioritizing Critical Quality Attributes (CQAs): measuring what truly matters for safety and efficacy. (11:50)Lessons from Roche/Genentech's QbD journey: regulatory insights and the business value of robust CQA identification. (15:55)The “CQA Reality Check” exercise: a step-by-step method to focus your team on attributes that impact patients. (21:05)How early, candid dialogue with regulators and using management tools like the Notion CMC Dashboard can streamline the development roadmap and reassure investors. (23:30)Ready to flip the odds in your favor and make QbD your competitive edge? Stream this episode to catch actionable strategies and real-world cautionary tales that could change your CMC development playbook for good.Next step:Book a 20-minute call to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/callPreparing for your IND? We're building a CMC Dashboard in Excel to help biotech founders track tasks, timelines, and risks in one place. Join the waitlist for early access at https://scale-your-impact.notion.site/27dd9c6ba679804b80a7ce439d56c91a?pvs=105

2:19: Once again, the 49ers live to die another day5:50: There is not one great team in the NFL, which means a “pretty good team”, like the 49ers, is gonna win it all7:51: The 49ers are right in this — so it's time to make a big move17:01: Fred Warner's jersey + Tatum Bethune — this kid might just be it25:40: ALCS Game 7 is the biggest game of the night — Sorry, MNF doubleheader35:32: Today in history: Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

49ers get vintage CMC in a win over the Falcons Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

10-20 Former NFL QB Todd Husak weighs in on appreciation for CMC while he is dominant & why he sees the 49ers as a contender despite injuriesSee omnystudio.com/listener for privacy information.

10-20 49ers reporter, Matt Barrows joins Papa & Silver to break down the Niners huge win vs the Falcons on Sunday Night Football behind a steamy CMC & killer defensive performanceSee omnystudio.com/listener for privacy information.

We love to hear from our listeners. Send us a message. On this week's episode of the Business of Biotech -- part three in a four part series recorded in-person at Catalyst Pharmaceuticals' Miami headquarters -- Anthony Japour, M.D., CEO at iTolerance, talks about his work as a physician treating infectious diseases, his CEO role in diagnostics at the height of the COVID-19 pandemic, what he learned working as a medical director at a large CRO, and iTolerance's work toward a cure for Type 1 diabetes that doesn't require chronic immunosuppression. Anthony also provides insights on overcoming CMC challenges and how to bypass avoidable detours, the funding climate for preclinical biotechs, and operating in South Florida. Access this and hundreds of episodes of the Business of Biotech videocast under the Business of Biotech tab at lifescienceleader.com. Subscribe to our monthly Business of Biotech newsletter. Get in touch with guest and topic suggestions: ben.comer@lifescienceleader.comFind Ben Comer on LinkedIn: https://www.linkedin.com/in/bencomer/

Media Markus is running the isolation as he discuss everything that happened around the NFL including a big night for CMC. Weekly awards and a preview of MNF double header. Lets win

start set the show00:05:00 Tough Memphis sports weekendGrizzlies injury news (WHY DO THE BASKETBALL GODS HATE THE GRIZZ!!!)00:23:00 Dirty Dozen (CFB)Memphis comes up short against UABDiego Pavia hitting the Money ManzielBilly Napier booed off the fieldStanford's goal line standUSC's weird trick play00:49:00 Gary ParrishMemphis loses to UABMore Grizzlies injury woesShohei Ohtani's big time performance01:16:00 Dirty Dozen (NFL)Bo Nix giving the Broncos their 1st lead (and the win)CMC is that dudePatrick Mahomes tricks the RaidersTitans new coach running stadiumsDanny Dimes throwing dimesHerbert's red zone pick01:28:00 CJ's Orlando Adventure

Week 7 had some iconic moments so who better to break it down for you than the iconic Iron Mike Carlson who this week is joined by Prop O 'Ollie Thornton' as Nat heads to New York for Quarterback tryouts at the Jets. The fellas start with the important topic of sumo wrestling being back in London before assessing whether the Jags are going to be forced into using Travis Hunter more as a receiver after his Wembley performance. They also discuss whether the 49ers are too reliant on CMC, if the Eagles can contend with an underperforming Saquon Barkley, whether people have finally stopped doubting the Colts plus, there is a brilliant breakdown from Mike on the QB situations in Miami, New York & Vegas. ___ To sign up for our brand new partners FanTeam, hit the link : ⁠⁠⁠https://af.fanteam.com/click?o=1&a=99082&c=1⁠⁠⁠ - use the code RUSH to unlock special offers for followers of The NC Show! Get involved in the Edge Rush Boosted Acca, the TNF Freeroll contest - free to enter - and more! FanTeam is the ultimate home for NFL fans in the UK, with season-long, weekly, and daily fantasy contests featuring regular five-figure guaranteed prize pools. Users have to be 18+, please play responsibly, BeGambleAware.org ___ Smokin' BBQ, ice-cold beers, and all the NFL action you can handle throughout the season. What's not to love, people? Check out Hickory's Smokehouse here: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://hickorys.co.uk⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ___ Check out the official Nat Coombs Show music playlist: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://open.spotify.com/playlist/0i1nSLaUJWxZMGCe8eJLQY⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ___ BONUS CONTENT! Subscribe to our YouTube Channel: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/@TheNCShow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ___ Follow Nat on X or Instagram: X (Twitter): ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twitter.com/natcoombs⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/natcoombs⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ___ NC Show socials: X (Twitter): ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twitter.com/thencshow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/thencshow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/thencshow/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Tik Tok: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.tiktok.com/@thencshow?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Threads: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.threads.net/@thencshow⁠ Learn more about your ad choices. Visit podcastchoices.com/adchoices

10-20 Former NFL QB Todd Husak weighs in on appreciation for CMC while he is dominant & why he sees the 49ers as a contender despite injuriesSee omnystudio.com/listener for privacy information.

Steiny & Guru believe last night's 201 total yard performance from Christian McCaffrey was a shot at everyone who has said CMC is beginning to show his age. He put the 49ers on his shoulders!

10-20 49ers reporter, Matt Barrows joins Papa & Silver to break down the Niners huge win vs the Falcons on Sunday Night Football behind a steamy CMC & killer defensive performanceSee omnystudio.com/listener for privacy information.

As usual, the boys break down every game of the NFL week and look ahead with some no brainers for week 8. Curt is exposed as a hypocrite for messaging players, and Dos' Dimes tackles the MVP list almost halfway through the season.The boys discuss:- Whether the Bengals are experiencing the Joe Flacco bump #whodey #flacco #cinci #steelersnation - The fake Jaguars 4-1 record #jags #duuuval - The Eagles' passing game getting going #eagles #flyeaglesfly #ajbrown #slimreaper - The Pats being a legitimate AFC East leader! #newengland #patriots #titans #titanup #tennessee - Carolina's shaky win over the deplorable Jets #nyjets #keeppounding #panthers - Chicago's four-game win streak under Ben Johnson #bears #chicago #whodat #saints - The dominance of the Chiefs and Patrick Mahomes over the Raiders #chiefskingdom - The Colts being the real deal and the Chargers struggling #danieljones #colts #boltup #lachargers - Mike McDaniel's tenure at the Miami Dolphins #finsup - The Cowboys' complete offense #dallas - CMC's massive day #49ers #sanfran Steelers 31 @ Bengals 33 Rams 35 v Jags (London)Eagles 28 @ Vikings 22Pats 31 @ Titans 13 (Pats are top of the AFC East!)Panthers 13 @ New York Jets (0-7)Dolphins 6 @ Browns 31 Saints 14 @ Bears 26Raiders 0 @ Chiefs 31Colts 38 @ Chargers 24Giants 32 @ Broncos 33Packers 27 @ Cardinals 23Commanders 22 @ Cowboys 44Falcons 10 @ 49ers 20Bucs @ Lions, Texans @ Seahawks todayRavens (1-5) and Bills (4-2) are on bye

Pushing biologics beyond 200 mg/mL isn't just a formulation challenge - it's a delivery, manufacturing, and regulatory challenge too. Aggregation, precipitation, and sky-high viscosity make scaling these therapies a gauntlet for drug developers.In this episode of Life Science Solutions, host Chris Adkins continues the conversation on hyper-concentrated biologics with Ryan Doxey, VP of Tech Ops & CMC at Kymanox, and Nick Letourneau, PhD, Associate Director of Product Development & Commercialization. Together, they unpack how dehydrated protein microparticles suspended in hydrophobic carriers (like MCT oils or ethyl oleate) can dissolve instantly upon injection, and why this breakthrough could dramatically ease the patient experience.The conversation dives deep into what this means for manufacturing, device compatibility, and regulatory pathways, revealing how the future of injectables depends on solving problems once thought unsolvable.Topics include:Why ultra-concentrated biologics often fail in aqueous solutionsHow microparticle suspensions dissolve rapidly in vivo to avoid depot effectsRheology 101: viscosity curves, shear-thinning fluids, and device designThe shift to aseptic manufacturing when sterile filtration isn't an optionPreclinical safety considerations and scaling studies from rodents to NHPsWhy early conversations with FDA's Emerging Technology Program matterThis is part two of our deep dive on concentrated biologics - picking up where our Podcast Marathon live episode left off.  This episode offers a rare look inside the formulation frontier — where drug science, delivery design, and patient experience intersect.

In today's top headlines Casey Warner has more on Florida firing Billy Napier, a recap of last night's SNF matchup where CMC tied an impressive record, and an update on the ALCS which will have a game seven tonight.

Andy and Randy get in to the keys for the Falcons to beat the 49ers, and as banged up as the niners are, Atlanta just can't let CMC run wild.

In hour 3, Spadoni and Sam discuss how CMC being around this year has given a layer that was not their last year, how does that effect the QB situation this year?

In an era of media consolidation, vanishing local newsrooms, and viral misinformation, the future of trusted journalism is at a crossroads. What happens to a community when its news megaphone splinters—when public media fights for survival, editorial independence is under pressure, and social media algorithms reward outrage over truth? Featuring: Philip Bump, Former National Columnist, The Washington Post, and Author, The Aftermath: The Last Days of the Baby Boom and the Future of Power in America Michelle Everhart-Sullivan, Chief Audience Officer, Signal Ohio Tareya Palmer, Co-Creator, Columbus Can't Wait Podcast The moderator is Mike Thompson, Director of Radio, WOSU Public Media.  This forum was sponsored by WOSU Public Media. The presenting sponsor of the CMC livestream was The Center for Human Kindness at the Columbus Foundation. CMC's livestream partner was The Columbus Dispatch.  This forum was also supported by Downtown Columbus, Inc. and The National Veterans Memorial and Museum. Ready to continue exploring this week's forum topic? The Columbus Metropolitan Library recommends reading What Works in Community News by Ellen Clegg and Dan Kennedy (2024). This forum was recorded before a live audience at The National Veterans Memorial and Museum in Columbus, Ohio on October 22, 2025.  

Andy and Randy start looking forward to the Falcons Sunday Night Football game vs the 49ers, and while the 49ers have said that they practice for Bijan Robinson, there is no way to simulate playing against him in any practice, even with CMC.

What happens when the most complex molecules in biotech meet the organizational challenge of managing 300+ analytical scientists? The answer lies not just in the science, but in building systems that turn technical complexity into reliable delivery.In Part 2 of our deep dive with Amanda Hoertz, VP of Analytical and Formulation Sciences at KBI Biopharma, we shift focus from the molecular intricacies of ADCs to the operational mastery required to scale analytical development across multiple sites. Amanda reveals how her team achieves consistency across hundreds of scientists while maintaining the agility to pivot priorities in real time when critical programs need emergency support.This isn't just about managing people; it's about architecting systems that preserve institutional knowledge, accelerate method transfer, and deliver results when regulatory deadlines loom.What you'll discover:Seamless Project Handoffs Without Knowledge Loss: How KBI's stable team assignments eliminate the costly learning curves that plague most CDMO relationships, ensuring your molecule expertise stays with your program from development through commercial manufacturing.Organizational Scale Without Operational Chaos: The decision tree and layered reporting structure that allows 200+ analysts at a single site to function as a coordinated force, capable of rapid reprioritization and flood-level resource deployment when programs reach critical status.Digital Transformation That Actually Works: Beyond the automation buzzwords, Amanda walks through the practical realities of LIMS/ELN implementation, audit-compliant systems, and machine learning databases that transform raw data into defensible, actionable insights for complex biologics.Whether you're evaluating how analytical capabilities scale with program complexity, or seeking practical insights into leading technical teams through digital transformation, this episode delivers the operational intelligence that separates successful ADC programs from expensive failures.Connect with Amanda Hoertz:LinkedIn: www.linkedin.com/in/amanda-hoertz-3aba605KBI Biopharma: www.kbibiopharma.comKBI Portal: www.standalone.kbi.bioNext step:Book a 20-minute call to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/call

Welcome to the Paint The Medical Picture Podcast, created and hosted by Sonal Patel, CPMA, CPC, CMC, ICD-10-CM.Thanks to all of you for making this a Top 15 Podcast for 5 Years: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://blog.feedspot.com/medical_billing_and_coding_podcasts/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sonal's 16th Season starts up and Episode 7 features a Newsworthy spotlight on October as Breast Cancer Awareness Month.Sonal's Trusty Tip and compliance recommendations focus on fine needle aspiration biopsies.Spark inspires us all to reflect on resilience based on the inspirational words of Elie Wiesel.Checkout the Workshop for Telehealth Playbook for 2025-2026 on: ⁠⁠https://kwadvancedconsulting.com/training-education-2/on-demand-webinars/webinar-registration/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Paint The Medical Picture Podcast now on:Spotify: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://open.spotify.com/show/6hcJAHHrqNLo9UmKtqRP3X⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Apple Podcasts: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://podcasts.apple.com/us/podcast/paint-the-medical-picture-podcast/id153044217⁠7⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Amazon Music: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://music.amazon.com/podcasts/bc6146d7-3d30-4b73-ae7f-d77d6046fe6a/paint-the-medical-picture-podcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Find Paint The Medical Picture Podcast on YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UCzNUxmYdIU_U8I5hP91Kk7A⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Find Sonal on LinkedIn:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/sonapate/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠And checkout the website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://paintthemedicalpicturepodcast.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠If you'd like to be a sponsor of the Paint The Medical Picture Podcast series, please contact Sonal directly for pricing: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠PaintTheMedicalPicturePodcast@gmail.com⁠⁠⁠⁠⁠

Ohio's water is one of its most valuable resources—critical for the state's health, environment, and economy. From reducing toxic algal blooms in Lake Erie to improving aging sewer and pipe systems and addressing polluted runoff, the stakes are immense. H2Ohio—a bipartisan clean water initiative launched in 2019—has made clear progress through collaboration with farmers, conservationists, and local governments.  But a budget reduction this year to the initiative of nearly 40% could slow or scale back some of these projects, prompting discussion among policymakers, environmental groups, and community leaders about the best path forward. What's at stake isn't just clean water—it's Ohio's health, environment, and long-term economic future.  Featuring: Dontavius Jarrells, Representative, 1st District, Ohio State House of Representatives Paula Powell, Senior Vice President, Research and Development, The Scotts Miracle-Gro Company Adam Sharp, Executive Vice President, The Ohio Farm Bureau Federation Bill Stanley, State Director, The Nature Conservancy in Ohio The host is Carol Kauffman, CEO, The Ohio Environmental Council This forum was sponsored by Burgess & Niple, Franklin Soil and Water Conservation District, The Alliance for the Great Lakes, The Green Funds of The Columbus Foundation, The Ohio Farm Bureau Federation, The Nature Conservancy, and The Ohio Environmental Council. The presenting sponsor of the CMC livestream was The Center for Human Kindness at the Columbus Foundation. CMC's livestream partner was The Columbus Dispatch. This forum was also supported by Downtown Columbus, Inc. and The National Veterans Memorial and Museum. Want to keep learning about this topic? Check out "The Last Drop: Solving the World's Water Crisis" by Tim Smedley, recommended by our partners at The Columbus Metropolitan Library.

What if the key to unlocking ADC manufacturing success lies in abandoning the platform mindset entirely?Antibody-drug conjugates represent biotech's most promising weapon against cancer: precision-targeted therapeutics that deliver cytotoxic payloads directly to tumor cells while sparing healthy tissue. But beneath the clinical promise lies a manufacturing reality that's rewriting the rules of bioprocess development, demanding analytical strategies that most CDMOs simply aren't equipped to handle.In this deep-dive episode, David Brühlmann sits down with Amanda Hoertz, Vice President of Analytical and Formulation Sciences at KBI Biopharma, where she oversees 300+ scientists across the mammalian network. Amanda's team has cracked the code on some of the industry's most challenging ADC programs, achieving a remarkable 93% batch success rate by rejecting cookie-cutter approaches in favor of molecule-specific development strategies.What you'll discover:The Platform Fallacy: Why treating ADCs like standard monoclonals is costing companies millions and months of development time, and the bespoke analytical framework that's changing everything.Cytotoxic Payload Management: From free drug analysis to employee safety protocols, Amanda reveals the hidden complexities of handling molecules designed to kill cells, including the specialized facilities and analytical methods required for GMP manufacturing.Charge Heterogeneity Mastery: The analytical method that "keeps Amanda up at night," and the development strategies her team uses to achieve robust separation and qualification across multiple sites and analysts.This episode delivers the technical depth and strategic insights that bioprocess engineers need to navigate ADC development successfully. Whether you're evaluating CDMO partnerships, optimizing analytical methods, or scaling complex conjugates, Amanda's proven strategies will transform your approach to these game-changing therapeutics.Ready to master the analytical complexities that make or break ADC programs?Connect with Amanda Hoertz:LinkedIn: www.linkedin.com/in/amanda-hoertz-3aba605KBI Biopharma: www.kbibiopharma.comKBI Portal: www.standalone.kbi.bioNext step:Book a 20-minute call to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/call

Are cell therapies the key to bridging the gap between discovery research and clinical trials? In the inaugural episode of the Bioprocessing Unfiltered podcast, Bo Wiinberg, chief business development officer at Novo Nordisk Foundation Cellerator, sat with Ran Zheng, CEO of Landmark Bio and shared his expert insight on the promise cell therapies hold for diseases with only treatments but no cures. Their conversation covers the challenges of navigating cell therapy programs through pre-clinical and clinical development journeys, how Cellerator is creating innovative spaces in CMC and manufacturing to fulfill critical needs in the translational space, and what a sustainable global cell therapy manufacturing landscape looks in 5-10 years. Links from this episode:  Bioprocessing SummitLandmark BioNovo Nordisk Foundation Cellerator Bioprocessing Unfiltered: Covering both upstream and downstream processing, analytics, AI and digitization, cell and gene therapy and more, Bioprocessing Unfiltered is your insider's pass to the researchers tackling—and solving—the day-to-day challenges in the bioprocessing industry.Evaluating Biopharma boiler: Evaluating Biopharma taps into the insight and experience of biopharmaceutical leaders so today's decision makers can leverage their knowledge, learn from their successes, and avoid repeating similar mistakes. This series offers a new guest and moderator with each episode and aims to equip executives and science leaders with the necessary information to make better business and process decisions. The Evaluating Biopharma podcast is a reproduction of content originally presented at recent Evaluating Biopharma digital and educational networking events.

0:53: “God damn it” — The Fred Warner show — ”Welcome to real sports pain”6:41: It can all be over in a flash, and that's why planning in the NFL is so hard12:29: How to approach the trade market:19:17: For all the injuries, it's the o-line that has ruined the 49ers23:19: The 49ers' second timeline failed, just like the Warriors' did25:02: Larry's argument for selling veterans like Trent Williams, CMC, and Kittle32:27: Larry's rant: The 49ers are driving cross country, and they just broke down in MODESTO1:04:27: DAMON: How come this coaching staff never coaches players up? LARRY: Can we get some new eyes on personnel?1:46:37: Looking ahead: 5-2 and 11 wins overall is still on the board Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In hour 2, Spadoni and Shasky discuss how they would evaluate CMC's play through the first third of the season.

Spadoni and Shasky discuss how teams now a days don't practice collectively enough. Podz and Kuminga have different leashes and the guys discuss why it is unfair to Kuminga. Plus, has CMC had a good season thus far? The guys preview the big matchup ahead this weekend in the crossover with Steiny and Gu!

Star 49ers running back Christian McCaffrey is off to a hot start offensively this season, showing shades of his 2023 AP Offensive Player of the Year campaign. McCaffrey sits down with Matt Maiocco to discuss a plethora of topics, such as learning route-running from his Super Bowl-winning father, identifying the most valuable asset in professional football and describing how George Kittle helps bring "fun" back into the game. Also, Jennifer Lee Chan stops by to update the 49ers' lengthy injury list and preview the potent Buccaneers offense San Francisco will face in Week 6, led by quarterback Baker Mayfield.--(3:00) 49ers and Bucs are very similar opponents(7:00) Malik Mustapha returns from ACL surgery(10:00) 49ers' lengthy injury updates(28:00) Christian McCaffrey 1-on-1 interview(34:00) Was CMC pressured to be receiver like dad?(39:00) CMC describes benefits of "competitive stamina"(41:00) CMC details the most valuable assets in football(43:00) CMC pinpoints 49ers' elite leadership structure, from staff to players(45:00) CMC describes how George Kittle brings "fun" to football Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Rudy's an executive coach, psychologist, restaurateur, writer, speaker, athlete and dad. His clients typically run at 3 – 5 times above median profit within our industry, and they get there within contract periods. He is a co-founder and curriculum creator for UCLA Extension's Hospitality Management Program and was an adjunct professor there for 13 years. Rudy is a Certified Management Consultant, CMC®. This certification is only given after meeting the highest global standards and ethical canons of the profession. Less than 1% of all consultants have achieved this level of excellence. He is also a member of Foodservice Consultants Society International (FCSI) and has served as a Worldwide board member, Chairman of the Americas, and Chair of Continuing Professional Standards for the Foodservice Industry. Rudy's worked with over 1,750 restaurateurs to shift their dreams to achieved goals. He & his team have over 350 successful restaurant start-ups. And, his client success is consistent in a myriad of industries: restaurants, hospitality, resorts, healthcare, technology, manufacturing, martial arts, retail, film, fitness and more. Rudy also gives his time as a consultant/coach for the Boulder Small Business Development Center. Rudy Miick has been a guest on Restaurant Unstoppable 5 times before. This episode is part 3 of a 3-part workshop all about the "Three Elements that Define Excellence" in your restaurant or organization. Join the Restaurant Unstoppable Network to join these workshops LIVE and aks the experts YOUR questions!  Join RULibrary: www.restaurantunstoppable.com/RULibrary Join RULive: www.restaurantunstoppable.com/live Set Up your RUEvolve 1:1: www.restaurantunstoppable.com/evolve Subscribe on YouTube: https://youtube.com/restaurantunstoppable Subscribe to our email newsletter: https://www.restaurantunstoppable.com/ Today's sponsors: Meez: Are you a chef, owner, operator, or manage recipes in professional kitchens? meez is built just for you. Organize, share, prep, and scale recipes like never before. Plus, engineer your menu in real-time and get accurate food costs. Sign up for free today and get 2 FREE months of invoice processing as a listener of the Restaurant Unstoppable Podcast. Visit getmeez.com/unstoppable to learn more. Restaurant Systems Pro - Join the 60-day Restaurant Systems Pro FREE TRAINING. This is something that has never been done before. This 60-day event is at no cost to you, but it is not for everyone. Fred Langley, CEO of Restaurant Systems Pro, will lead a group of restaurateurs through the Restaurant Systems Pro software and set up the systems for your restaurant. During the 60 days, Fred will walk you through the Restaurant Systems Pro Process and help you crush the following goals: Recipe Costing Cards; Guidance in your books for accounting; Cash controls; Sales Forecasting(With Accuracy); Checklists; Budgeting for the entire year; Scheduling for profit; More butts in seats and more… Click Here to learn more.  Let's make 2025 the year your restaurant thrives. Guest contact info:  Connect with Rudy via Restaurant Unstoppable The Miick Companies website Email: rudy@miick.com Thanks for listening! Rate the podcast, subscribe, and share! 

What if solving tomorrow's bioprocessing challenges meant questioning the very physics of chromatography and reimagining downstream processing from the ground up?For years, large biomolecules like viral vectors and exosomes have squeezed through the limitations of traditional chromatography, leaving scientists to wrestle with capacity trade-offs and slow mass transfer. But what if a fundamental shift could unlock breakthroughs for gene therapies, vaccines, and advanced biologics?In this thought-provoking episode, host David Brühlmann sits down with Alois Jungbauer, professor emeritus of downstream processing at BOKU University (Vienna) and scientific advisor at BioChromatographix International. Together, they examine the future of chromatography and downstream processing, exploring innovations that tackle the challenges of modern gene therapy, advanced therapeutics, and sustainability in manufacturing.Alois shares his perspective on anticipating industry needs, the importance of mentorship, and why the physical limits for purification of large biomolecules are yet to be reached.Episode Highlights:The difference between solving current problems and anticipating the needs of the next generation in biotech (00:00)The promise and technical details of monolithic chromatography and its application for large modalities like gene therapy vectors and exosomes (03:01)Explanation of “inverted morphology" and AXISFLOW™ in new chromatography materials (03:18)Challenges and opportunities in continuous gene therapy vector production, and why it's not widespread yet (07:40)The critical role of sustainability in downstream processing, particularly water usage and its impact on the viability and costs of distributed manufacturing (10:30)The relationship between reducing water consumption, manufacturing footprint, and cost of goods (12:16)Advice on scientific career development: listening, reading, understanding future industry needs, finding a mentor, and having persistence (13:50)Broader reflections on the value of science, societal perceptions, and science communication in today's world (17:34)Alois's key takeaway: downstream processing for gene therapy has not yet reached its physical limits—there is still significant room for improvement (20:26)If you're looking for fresh strategies to tackle the bottlenecks of large-molecule purification - and a candid perspective on where the real opportunities and societal responsibilities lie - you won't want to miss this conversation.Connect with Alois Jungbauer at leading conferences, including Bioprocessing Summit and Bioprocessing International, or find the next integrated continuous biomanufacturing event where he's co-chairing.Connect with Alois Jungbauer:LinkedIn: www.linkedin.com/in/alois-jungbauer-14984811Website : www.biochromatographix.comNext step:Book a 20-minute call to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/callPreparing for your IND? We're building a CMC Dashboard in Excel to help biotech founders track tasks, timelines, and risks in one place. Join the waitlist for early access at

Welcome to the Paint The Medical Picture Podcast, created and hosted by Sonal Patel, CPMA, CPC, CMC, ICD-10-CM.Thanks to all of you for making this a Top 15 Podcast for 5 Years: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://blog.feedspot.com/medical_billing_and_coding_podcasts/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sonal's 16th Season starts up and Episode 6 features a Newsworthy update on the OIG Work Plan for September 2025.Sonal's Trusty Tip and compliance recommendations focus on another update regarding E/M scrutiny by a payor.Spark inspires us all to reflect on resilience based on the inspirational words of Madeleine L'Engle.Checkout the Workshop for Telehealth Playbook for 2025-2026 on: ⁠https://kwadvancedconsulting.com/training-education-2/on-demand-webinars/webinar-registration/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Paint The Medical Picture Podcast now on:Spotify: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://open.spotify.com/show/6hcJAHHrqNLo9UmKtqRP3X⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Apple Podcasts: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://podcasts.apple.com/us/podcast/paint-the-medical-picture-podcast/id153044217⁠7⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Amazon Music: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://music.amazon.com/podcasts/bc6146d7-3d30-4b73-ae7f-d77d6046fe6a/paint-the-medical-picture-podcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Find Paint The Medical Picture Podcast on YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UCzNUxmYdIU_U8I5hP91Kk7A⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Find Sonal on LinkedIn:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/sonapate/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠And checkout the website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://paintthemedicalpicturepodcast.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠If you'd like to be a sponsor of the Paint The Medical Picture Podcast series, please contact Sonal directly for pricing: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠PaintTheMedicalPicturePodcast@gmail.com⁠⁠⁠⁠

1:32: Matt Maioco joins the show7:00: If the 49ers reach 5-1, will the front office be more aggressive at the deadline?10:48: Who are the 49ers? Because so far, they've gotten away with football murder14:51: Kyle has to be worried about CMC's workload, right?18:14: Why is Brian Robinson Jr. such a square peg in a round hole?22:09: Is there a quarterback controversy?!24:37: Why was Brock Purdy brought back so fast?27:53: How was Kyle talked into (or talked himself into) Trey Lance over Mac Jones?32:40: How about Mac sticking the landing in the press conference when he was asked if he's the starter?37:34: What's Kyle's psychological coaching profile? And what's the secret to keeping his message fresh to his players?53:52: Is Fred Warner the best player in football, as Matt said?1:07:11: Today in history: Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In this episode, host David Brühlmann is joined by Alois Jungbauer, Professor Emeritus at BOKU University, Vienna, and Scientific Advisor at BioChromatographix International. With over 40 years in bioprocess engineering and more than 400 published papers, Jungbauer offers a unique perspective on how downstream processing and purification technologies have evolved and where they're headed next.Alois shares his unconventional journey into the world of biotech, starting from humble beginnings on an Austrian farm, and discusses key turning points that have shaped the industry. Together, they explore the latest challenges triggered by high cell culture titers, new therapeutic modalities, and the drive for automation and process integration in manufacturing.In this episode:Why the gap between upstream and downstream processes remains a core bottleneck (03:27)How rigid and convective chromatography materials changed throughput and efficiency (06:56)The shift in purification strategies with skyrocketing titers in cell culture (08:43)Automation and integrated biomanufacturing: their role in making processes more robust and continuous (10:20)Misconceptions around resin costs in full-scale versus clinical-scale manufacturing (12:10)What automation and process monitoring mean for real-time release and factory scheduling (14:05)The resurgence and application of displacement chromatography for gene therapy vectors (15:49)Whether you're deep into process development or just curious about the next wave in biotech manufacturing, Alois Jungbauer's insights offer valuable context for the road ahead.Connect with Alois Jungbauer:LinkedIn: www.linkedin.com/in/alois-jungbauer-14984811Website : www.biochromatographix.comNext step:Book a 20-minute call to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/callPreparing for your IND? We're building a CMC Dashboard in Excel to help biotech founders track tasks, timelines, and risks in one place. Join the waitlist for early access at https://scale-your-impact.notion.site/27dd9c6ba679804b80a7ce439d56c91a?pvs=105

Damon and Damo catch up as Damon highlights his first week as a CMC. Damo had to shave his mustache and did not like it one bit. The guys discuss the impact of the current furlough on servicemembers and civilian teammates, along with available resources for anyone in need. Diddy was sentenced to four years in prison after a guilty verdict in a prostitution case, and Damon makes a plea against political violence and mass shootings. Earlier this week, Secretary of Defense Pete Hegseth and President Trump called top military generals and admirals to Quantico for a brief, summit, conference, or “All Call.” At the same time, the SecDef dropped a load of memos focused on refocusing the fleet and putting the warrior spirit at the forefront. This week's hero is Pfc. Jacklyn Harold Lucas, and last week's “Do Better” segment gets a much-needed follow-up with a shout-out to Freddy Whisner. A new listener-submitted “Do Better” sparks a conversation about how DRB can be handled more privately. The guys also debate whether the Super Bowl music choices alienate two-thirds of the NFL's fanbase as Damo praises PTA and Leo's latest movie, One Battle After Another, and much more.     Do you have a “Do Better” that you want us to review on a future episode? Reach out at ptsfpodcast@gmail.com       Stay connected with the PTSF Podcast: https://linktr.ee/Ptsfpodcast       Links and more from this episode:   FY26 Government Shutdown Resources - https://stjececmsdusgva001.blob.core.usgovcloudapi.net/public/documents/2025_Guide_to_Fleet_for_Government_Shutdown.pdf   Hero of the Week: Private First Class Jacklyn Harold Lucas https://www.cmohs.org/recipients/jacklyn-h-lucas   Picks of the Week: Damo: Chance The Rapper - Starline https://chancestuff.com/?srsltid=AfmBOorWA02aAprglTEVCypj5YxOlRdh4TGV531SgdcqPPUpNrTYIoBT   Damon: BMW       PTSF Theme Music: Produced by Lim0

Rudy's an executive coach, psychologist, restaurateur, writer, speaker, athlete and dad. His clients typically run at 3 – 5 times above median profit within our industry, and they get there within contract periods. He is a co-founder and curriculum creator for UCLA Extension's Hospitality Management Program and was an adjunct professor there for 13 years. Rudy is a Certified Management Consultant, CMC®. This certification is only given after meeting the highest global standards and ethical canons of the profession. Less than 1% of all consultants have achieved this level of excellence. He is also a member of Foodservice Consultants Society International (FCSI) and has served as a Worldwide board member, Chairman of the Americas, and Chair of Continuing Professional Standards for the Foodservice Industry. Rudy's worked with over 1,750 restaurateurs to shift their dreams to achieved goals. He & his team have over 350 successful restaurant start-ups. And, his client success is consistent in a myriad of industries: restaurants, hospitality, resorts, healthcare, technology, manufacturing, martial arts, retail, film, fitness and more. Rudy also gives his time as a consultant/coach for the Boulder Small Business Development Center. Rudy Miick has been a guest on Restaurant Unstoppable 5 times before. This episode is part 2 of a 3-part workshop all about the "Three Elements that Define Excellence" in your restaurant or organization. Join the Restaurant Unstoppable Network to join these workshops LIVE and aks the experts YOUR questions!  Join RULibrary: www.restaurantunstoppable.com/RULibrary Join RULive: www.restaurantunstoppable.com/live Set Up your RUEvolve 1:1: www.restaurantunstoppable.com/evolve Subscribe on YouTube: https://youtube.com/restaurantunstoppable Subscribe to our email newsletter: https://www.restaurantunstoppable.com/ Today's sponsors: Meez: Are you a chef, owner, operator, or manage recipes in professional kitchens? meez is built just for you. Organize, share, prep, and scale recipes like never before. Plus, engineer your menu in real-time and get accurate food costs. Sign up for free today and get 2 FREE months of invoice processing as a listener of the Restaurant Unstoppable Podcast. Visit getmeez.com/unstoppable to learn more. US Foods: US Foods is hosting the event of the year, Food Fanatics 2025. August 19-20, 2025, at the Mandalay Bay, Las Vegas, NV. Network with over 5,000 Industry peers. Attend Zouk nightclub reception, expert breakout sessions, Keynote speeches, musical performances, and dramatic demonstrations, and sample the latest on-trend dishes. The Clock Is Ticking! Be Ready to Register on April 16 for Food Fanatics® 2025. To learn more, visit www.usfoods.com/foodfanatics2025 Restaurant Systems Pro - Join the 60-day Restaurant Systems Pro FREE TRAINING. This is something that has never been done before. This 60-day event is at no cost to you, but it is not for everyone. Fred Langley, CEO of Restaurant Systems Pro, will lead a group of restaurateurs through the Restaurant Systems Pro software and set up the systems for your restaurant. During the 60 days, Fred will walk you through the Restaurant Systems Pro Process and help you crush the following goals: Recipe Costing Cards; Guidance in your books for accounting; Cash controls; Sales Forecasting(With Accuracy); Checklists; Budgeting for the entire year; Scheduling for profit; More butts in seats and more… Click Here to learn more.  Let's make 2025 the year your restaurant thrives. Guest contact info:  Connect with Rudy via Restaurant Unstoppable The Miick Companies website Email: rudy@miick.com Thanks for listening! Rate the podcast, subscribe, and share!