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Jim Cybulski is a co-founder of Foldscope, the ultra-affordable, paper microscope that you assemble yourself. Designed to be inexpensive, durable, and to give optical quality similar to conventional research microscopes, Foldscope brings hands-on microscopy to new places! It has reached over 1 million people and created a global community of explorers unlike any other!Foldscope is a company that develops low-cost scientific tools with the mission of making science accessible to everyone around the world. Foldscope is rugged, durable, and 100% waterproof; with over 1,000X magnification with digital zoom, it resolves single-cell bacteria (0.18 NA). You can learn more about us in this PDF. Foldscope is a powerful tool that allows students to carry on scientific explorations anywhere - which makes it perfect for remote learning! You can read about the impact Foldscope has been having on students of the Ector County Independent School District (Texas, US) here.Connect with Jim & Foldscope:Website foldscope.comYouTube youtube.com/channel/UC8jNuT-a9rqdrtBYxDPYuOQTwitter @teamfoldscopeFacebook facebook.com/foldscopeInstagram @teamfoldscopeChris Woods is the host of the STEM Everyday Podcast... Connect with him:Website dailystem.comTwitter @dailystemInstagram @dailystemYouTubeGet Chris's book Daily STEM on Amazon Support the show (http://dailystem.com/stem-everyday-podcast/)
90% of information transmitted to the brain is visual and it is perceived 60,000X faster than text. What does this tell us? Video marketing is no longer a "nice-to-have." Rather, it is a necessity for brands of all sizes to better connect with customers and partners, communicate your messages, improve brand experiences and break through the noise to capture attention. Video use cases are endless - from partner training and engagement to product introductions and sales pitches. Video can also be the key to gaining traction with a customer at the right time throughout their entire buying journey. We know video works, so why do so many companies still shy away from creating an arsenal of video marketing content? Robert Cassard, CEO & Co-Founder of Voodoo Video chats with 360insights' Reggie Waterman about the power of video, the latest video trends, its perceived challenges and ways to use this medium to achieve mind-blowing ROI.
Dans ce chapitre 000X, Le grand maître des jeux est Doom.
Everyone has wondered if they can save money by going the variable route, whether it’s with student loans, mortgages, or insurance. And variable can be sweet... If you can get it right. But there is POWER in predictability, as was showcased in Texas this past week with variable electricity rates that shot up 9,000X the alternative fixed rates. So, where and when can variable rates rule? We explore the decision tree that exists in a slew of other financial areas.
Math here helps illustrate spiritual truth.Here is how I figure this about an ungrateful servant.he owes his King $10 BILLION debthe doesn't realize the extent of his debt and thinks it is in the realm of repayingthe first servant also has a servant that owes him $12,000 (not an insignificant amount)the first servant's debt to the King is 833,000X bigger than the debt the second servant owes to the first servantEven if the first servant forgives the second servant 7 times, (Which is what Peter's first question proposed) the first servant's debt to the King is 119,000X biggerUnless this first servant gets the math right, and appreciates his massive, unpayable, disproportionate debt to his KING, he won't get the motivation for the right actions to his fellow human. Without good ACCOUNTING (to God) spiritually, we are apt to err in our ATTITUDES and our ACTIONS (to others). Listen with your calculator.
Verlierst du dich häufig in deinen Gedanken? Erinnerungen aus der Vergangenheit, oder Sorgen über die Zukunft? Dann ist die heutige Podcastfolge für dich. Warum die Gegenwart ein Geschenk ist, wie sie alles was du tust 1.000X besser macht, und wie du mit Leichtigkeit in der Gegenwart (ohne plappernden Verstand lebst), das erfährst du heute. Viel Spaß! P.S. du kennst jemanden dem dieser Podcast gefallen würde? Teile den Podcast mit ihm! P.P.S der in der Folge erwähnte Link für deine kostenlose Coachingsession: www.alexanderwahler.com/coaching
For the past 35 years, Ben Rewis has been a leader in the development and deployment of cutting-edge enterprise technology within large financial-services companies. With a renewed passion for AI, Ben is now advising companies ranging from startups to global corporations on digital transformation and the massive opportunities around innovative uses of AI. A surfer buddy of Cloud Wars Live monthly guest Christopher Lochhead, Ben joins us today to share some compelling ideas on AI's vast potential for both good and evil.Ben starts out by saying he got into working for a big insurance company, but he eventually relocated from Maine to California to join VISA – where he ran internet eCommerce services. Then, he moved to JPMorgan Chase and started looking at the fraud algorithms associated with real-time transaction processing.He says as a student of tech, he already sees AI making a big difference in lots of industries – including healthcare, automotive, financial services, retail, telecommunications, manufacturing, etc. He says there are going to be 41 billion devices and 79 zettabytes by 2025 – and they are all benefiting from AI.Ben says he does consulting work for the ag-tech industry. He says an apple tree has 2,000 blossoms and farmers want to cut it from 150 – so you don’t get the little golf-ball sized apples, you get the big, juicy ones. That’s 1,000X transformation – or 10,000X transformation.Ben says things like miniature drones can be weaponized – and just like nukes they could get into the wrong hands. He says this is the most pressing ethical issue we face around safety, and particularly what war represents for our planet. Ben says there’s a ton of benefit for humankind, but also a ton of risk.I tell Ben that an IBM executive, John Kelly, visited the Vatican – and the Pope – and he spent most of the time discussing the notion of bias. Ben says that there’s a challenge with ML systems. They’re not like traditional products and can’t be conjoined with another dataset. For example, a computer vision camera producing class one, and another set of cameras producing class two won’t be the same algorithm.Ben says he loves working with teams that are doing digital transformation – whether it’s a Fortune 100 or a startup. He says he helps teams think through their products and business strategies, and if it’s a big company looking for transformation he is happy to do that too.He says he found technology and wilderness at the age of 17. He says he found nature to be a really great teacher. Ben says pay attention to what it means for your kids’ kids, and try to the leave the world a better place.His website is benrewis.com. See acast.com/privacy for privacy and opt-out information.
Question: Could low LDL hurt female fertility? I haven't seen evidence of it, but that would not surprise me at all given that cholesterol is what you make sex hormones from. If you see levels that low, I don't know that it's intrinsically a problem. You kind of want to start looking at what are the reasonable things you could expect to happen from that that affect female fertility? Fat-soluble vitamins could be relevant. Sex hormones could be relevant. I'd start looking at those things. I doubt that the LDL being that low itself in and of itself is going to be the thing that compromises fertility. This is the thing. Is the LDL low because of really good clearance from the blood, or is it low because of really low production? If it's low because of really low production, then you definitely have problems with fat-soluble vitamin transport. Because if the liver is not making lipoproteins as much, the fat-soluble vitamins are staying trapped in the liver and they're not getting to other tissues that need them. While there's no evidence for it, it makes perfect sense that dietary cholesterol would help that because dietary cholesterol is very helpful in Smith-Lemli-Opitz syndrome, where the exact same defect is 1,000X to produce a devastating result. It makes total sense that in someone who is a carrier for SLOS, Smith-Lemli-Opitz syndrome, who has defective cholesterol synthesis in their gonadal tissues and therefore has defective sex hormone synthesis, it makes total sense of eating cholesterol would help those people. So, I would try it. Egg yolks. That's what most people are going to eat for cholesterol. But this all hinges on the question of the LDL is low, so what? Is it because it's being cleared rapidly or because it's not entering the blood due to lack of synthesis? Whether that person is going to have infertility as a result of it and whether that's going to be helped by dietary cholesterol, it's all going to get a hinge on that. But the good news is for both people, it's probably completely harmless to eat some eggs. Eating eggs might just be the thing that helps. This Q&A can also be found as part of a much longer episode, here: https://chrismasterjohnphd.com/podcast/2019/03/30/ask-anything-nutrition-march-4-2019 If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up with a 10% lifetime discount here: https://chrismasterjohnphd.com/q&a
Today we take a close look at the Olympus DSX1000 Digital Microscope, which boasts a 20–7,000X magnification range and the ability to instantly switch between six observation methods. Fast motorized optical zoom lets you optically zoom in and out by simply turning the dial on the console. Advanced algorithms enable you to capture high-resolution 3D images just by pushing a button.
This paper is part of NMJ's 2018 Microbiome Special Issue. Download the full issue here. In this interview Natural Medicine Journal's editor-in-chief, Tina Kaczor, ND, FABNO, and Steven Sandberg-Lewis, ND, DHANP, discuss the integral role of the gut microbiota in mood and cognition. A review of how the gut and brain communicate through both the nerves and gut microbial metabolites is discussed. They also talk about how intestinal permeability and brain permeability are associated and what you can do about it. As a naturopathic clinician with over 40 years' experience, Sandberg-Lewis shares some clinically useful pearls along the way. About the Expert Steven Sandberg-Lewis, ND, DHANP, has been practicing since 1978, teaches gastroenterology at National University of Natural Medicine and has a private practice at 8Hearts Health and Wellness in Portland, Oregon. He lectures, presents webinars and interviews on issues of digestive health. He is the author of the medical textbook Functional Gastroenterology: Assessing and Addressing the Causes of Functional Digestive Disorders, Second Edition, 2017. His column Functional Gastroenterology Bolus appears regularly in the Townsend Letter. Within gastroenterology, Sandberg-Lewis has special interest and expertise in inflammatory bowel disease, irritable bowel syndrome, small intestine bacterial overgrowth (SIBO), hiatal hernia, gastroesophageal and bile reflux (GERD), biliary dyskinesia, and chronic states of nausea and vomiting. He lives in Portland with his wife, Kayle. His interests include mandolin, guitar, writing, and lecturing. Transcript Tina Kaczor, ND, FABNO: Hello, I'm Tina Kaczor with the Natural Medicine Journal. I'm speaking today with Dr. Steven Sandberg-Lewis and our topic is the gut-brain axis. Dr. Sandberg-Lewis has been a practicing clinician for over 40 years now and he is the author of Functional Gastroenterology: Assessing the Causes of Functional Gastrointestinal Disorders, and that has come out in a second edition as of March 2017. He's also adjunct full professor at the National University of Natural Medicine. Dr. Sandberg-Lewis, thank you so much for joining me today. Steven Sandberg-Lewis, ND, DHANP: You're welcome. Kaczor: Alright, so I think our talk about the gut-brain axis is extremely timely because of the media attention now given to the bacteria and the effect of our microbiome on our physical ailments and I think it's beginning to look at how it effects the brain both cognition and mood as well. And so, what I'd like to do is really start at the beginning and can you just give us a quick overview of what exactly do we mean when we talk about the gut-brain axis? Sandberg-Lewis: Yeah, naturopathic medicine seems to always be at least 30 years ahead of the rest of medicine. We've been talking about this a long time but now we have a lot of research to back up what we talk about. So, the gut-brain axis probably has many more players than we're aware of but the ones we know about are, of course, the microbiota, a lot of people call that the 'microbiome'. But it's the bugs. About 100 trillion of them and they are, of course, not just in the colon but in the small bowel, in the stomach, which is not sterile and the oral and esophageal areas. The true meaning of microbiome is the genome of the gut floor which has way more, at least 100X more genes than the human genome, which is 26,000. And when you put the two together, you call it the 'holobiome', which is the human genes and the microbial gene. But really, you need to do that because they interplay so much and the bugs really control our genome so intensely. Then there's that whole genetic piece then there's all the, what we call the metabolon. What the bugs and the enteric cells make, all their metabolic products and that includes secretory IGA, short chain fatty acids, lipooligosaccharide, bacterial hormones and neurotransmitters and cytocinesis. We can talk about all those kind of details. And then of course there's the enteric nervous system speaking to the vagus and the vagus speaking back. And there's the HPA axis and then there's the immune system and the gut. So, it's huge. It's so much talk it's deafening crosstalk. Kaczor: It is interesting and one of the pleasures, I think, I've been practicing nearly 20 years and I know that you've been practicing over 40 eyras so, it's quite a long time to watch the evolution of thought processes in medicine as well as the population at large. And in some of the folk medicine even, naturopathic medicine, but good old folk medicine, an apple a day and staying regular and keeping the bowels moving, it's amazing how that comes back at us and now we're talking about it in scientific terms which is fascinating to watch the pendulum swing. Okay so, when we talk about how they communicate, you gave a little overview of some of the ways, when you mention the vagus system, what do you mean exactly? Sandberg-Lewis: On every new patient, I like to have them open their mouth, stick out their tongue, take a look at their palatal arch and their uvula and then have them say 'ah'. When they phonate, we've all done this, check the vagus nerve. The place you can check the vagus nerve directly is there in the palate because the levator palatini muscles on either side raise the palate when you say 'ah' and when you phonate. So, I'd like to see both arches go up symmetrically and not an asymmetrical rod. Occasionally you see nothing. The patient says 'ah', nothing happens. There's no palatal rise and you can have them do it over and over and nothing happens. So, that's a sign that the vagus isn't really firing the way it's supposed to and there are lots of ways to try and improve vegul tone. But that's a good thing to know about your patient. The next thing is the vagus nerve gets sensory information from the enteric nervous system and the neuroendocrine cells in the gut as well as the epithelial cells. It gets input in actually 90% they assume, 90% of the crosstalk is from the enteric nervous system to the Brian through the vagus. So, it's mostly the gut talking to the Brian and then the brain through the vagus talks back about 10% of the time. So, there's direct transmission through the nerves and then there's all the cytocinesis and other factors and neuro peptides that also speak through the humoral method. Kaczor: So, what you're saying is the gut itself is sending signals through the vagus nerve to the central nervous system and effecting what exactly? Sandberg-Lewis: So, yeah. It's pretty interesting what the gut is interested in talking about. Yeah, you wonder, what does my gut have to say? What does it care about? So, what the gut is saying, the 90% of impulse is going from the gut to the brain, it's talking about the shape and the consistency of the bowless of food moving through and scraping up against the ... rubbing up against the mucosa. The sheering forces of the bowless against the mucosa. That's stimulating serotonin locally but there's also this ... That's what the gut's interested in. Is, what kind of food is it, what's the shape, what's the consistency and what does it feel like as it rubs against the enteric cells? This seems to stimulate taste receptors on the antero endocrine cells that are scattered throughout the mucosa and give information about the composition of the food, there's, again, there's all these neuro peptides and hormones, GI hormones that are released as well. But directly through the vagus nerve, we think it's mostly the gut talking about it's scratchiness of the food and the size and the consistency and the kind of food. Kaczor: Okay. And I have to clarify for my own self, when you say 'taste receptors', you're going beyond the tongue? Is that what I hear you saying? Is this "taste receptors" that you say along the GI tract, how does that work? Sandberg-Lewis: Air quotes, well, our genius in our midst, Paul [Calmens 00:08:18], he's been telling me for years that there are taste receptors throughout the entire gut. And especially most pronounced is the bitter, bitter receptors. And I've tried to go into the research and find out what exactly they do. We don't know a lot about what they do but we know that bitter receptors are not just in the tongue and the mouth, they're throughout the whole gut and they seem to trigger the release when they're stimulated. They trigger the release of ghrelin and glucagon peptide one which have to do with blood sugar balance and hunger and my guess is, Flip Wilson used to say, "The devil made me do it" when he did something that he thought was nasty. But I really think that in many ways, the GI flora and the food that we eat interact to create cravings so that the body can get what it needs. And if you get more ghrelin, you get hungrier. And certain other, like GLP, maybe you're gonna create more sugar. It's really important, of course, to eat food ... I think this is why Indies think it's so important to eat foods that's close to nature because once you get these synthetically modified foods or their consistency and their flavor and their compositions is altered, it probably throws off these natural mechanisms that tell us when to eat, when not to eat, when our blood sugar is fine, when it needs to go up or down. So, these are really finely tuned things. Kaczor: Yeah, it's interesting in context, again, of traditional medicines because it automatically makes me think of Ayurvedic medicine and other traditional practices that naturally balance the flavors on the plate, that's a big part of making sure each meal is healthy in that tradition. So, let's talk about the microbiotas some more. You mentioned briefly that its metabolites are part of the talk between the gut and the brain, can you elaborate on that? Sandberg-Lewis: Yeah. First of all, I wanted to mention that the metabolic byproducts, the products of the microbiota, it's huge, it's huge. And Emerson Mayor's book, the gut-brain connection, he makes a quote that 40% of the metabolites in human blood are derived from gut flora, which blew my mind completely. And so, I said, "Where is he getting that?" And I looked, I found it in two or three different articles. And so, to me, that means 40% of our blood chemistry is derived from the intestinal flora. And that makes sense since there are at least 10-to-1 more of them than there is of us in terms of cells. But I never really put that together. So, there's these metabolites in our blood derived from the flora that do fine tuning of eating behavior, mod, blood glucose, digestive secretion, absorption, motility, just it's mind blowing. It's so important and it makes sense. You can understand that when you go ahead and even just take a broad spectrum antibiotic, we know that greatly increases the risk of kids and even adults, getting inflammatory bowl disease, especially Crohn's. Just so many effects on immunity and the balance within the body if we knock down the bacteria or alter them or decrease their diversity. So, pretty important, pretty major stuff that everybody's been messing around with since the 1920s and '30s with antibiotics. Kaczor: Mm-hmm (affirmative). Yeah and you mention a metabolite that caught my attention because I think it's at least in our naturopathic circles, we're paying a lot of attention to the role of that lipopolysaccaride and the LPS, for short. Can you talk a little bit about that? Because I feel like that's, as far as I can see, getting a bit of attention these days in how the gut and brain effect one another. Sandberg-Lewis: Yeah well, I'm glad it's getting attention, it deserves it. You know, every physician knows about LPS in one particular way and that is, it is the cause of septic shock. It kills people if the LPS is high enough. What we don't usually hear about and we're starting to get more and more research on is, what about physiological levels of LPS when it's not super high? Sandberg-Lewis: LPS is used in research, they inject it into lab animals to activate the NF kappa B pathway of inflammation and there's a tremendous amount of it. These are from the gram-negatives. The gram-positives also have an inflammatory precursor like this, which is the peptidoglycan. But, mostly we talk about the gram-negative because it's so potent and there were a million copies or so of LPS in each gram-negative microbe and it's not just something that gets emitted when the bug dies, it's also just when it's replicating or if you take an antibiotic and weaken it a little bit, they don't have to die to give off LPS. And it's thought that in the adult human gut, you have up to a gram of LPS, a thousand milligrams at any one time. So, it's a major player. There's a lot of it and it can trigger the Zonulin pathway, which leads to intestinal permeability, hyperpermeability, which we know is related to autoimmunity and allergies. Obese humans have up to a three fold increase in LPS compared to lean and maybe some of that also dove tails with the fact that obese adipose tissue has 10X as many macrofacies. So, you got a lot of esocine activity, a lot of TNF alpha. Kaczor: Mm-hmm (affirmative). Sandberg-Lewis: And different types of enteric flora have different amounts of LPS. Or even different potentiates. So, antero bacter are thought to have some of the most potent LPS that can be up to 1,000X more potent than some of the other gram-negative bacteria. So, this is a major toxin, it's a major provoker of inflammation and pre radical activity in all kinds of changes. Kaczor: So, how does LPS effect the brain directly? Since, I hear what you're saying and I know even in experimental animals LPS is a common way to reliably instill an inflammatory process in a lab animal. So, it's clearly a very potent, inflammatory molecule. How does it effect the brain? Sandberg-Lewis: So, the bacteria, we get some bacteria trans locating into the blood but they usually get called out after they travel through the portal vein to the liver by the cooper cells. At least if the liver's working well. You're not gonna have a lot of bacteria in the blood but the bacteria can still effect the central nervous system, even if they don't cross the blood brain barrier and never even get there. First of all, one mechanism is that LPS and the inflammatory cytocinesis that it induces include interleukin one, interleukin six and I mentioned TNF alpha and they can actually up regulate the transcription of these cytocinesis in certain discrete areas of the brain. And then one of the things that happens with that is, within the brain you get an up regulation of indoleamine dioxygenase, which is that enzyme that converts tryptophan to kynurenine and that can move further to quinolinic acid, which is neurodegenerative. Although, there's quinolinic acid, which is also has a positive effect. So, depending on how it goes through the pathways, you can have neuro degeneration up regulated. And studies show that depression, anxiety and insomnia can issue from high levels of quinolinic acid. So, there's that. There's also cognitive deficits and in my book, very important, is increased visceral sensitivity. All the functional disorders of the GI tract, there is increased visceral sensitivity meaning, people perceive their own motility and movement within the gut as pain or strong discomfort. And man, those patients are strong to treat because if you start to activate their GI tract and get it moving again after it's been atonic for years, then they're complaining that they're up all night with abdominal pain. And that's a tough one, we're trying to learn more about how to deal with visceral hypersensitivity. But, it's thought that LPS is one of the things that triggers that too. Kaczor: So, I have a two part question. I guess, in our clinical assessment of LPS, is there a means, I mean, I know that we could do testing for small intestine bacteria overgrowth through breath testing but, is there any blood test, I guess is what I'm thinking? Can you tack on any blood test to gauge LPS levels and the second part of this question is, what do we do about it? I suppose treating the gut in a totality dysbiosis present, is the short answer. Any clinical pearls are certainly welcome. Sandberg-Lewis: Yeah. So, you can, this is available, you can measure LPS. You can measure LPS binding protein, I believe as well. And you can, in your patients, you can, of course, measure zonulin, which gets up regulated by LPS. So, yeah. By all means, start experimenting with that and then see if you can get the levels down. Now, yeah. I'm known for spearheading along with some other really busy physicians and researchers. The treatment and in our case, more the natural treatment, of small intestine bacterial overgrowth, you just can't get away from it. It's so key to, we used to say, "Death begins in the colon" when I was in school in the 1970s and now, I think it makes sense to say, "Disfunction and autoimmunity begins in the small intestine". It's just associated with so much and that includes neurodegenerative diseases, like Parkinson's as well. A practical thing, yeah. Learn how to test for, interpret and treat ... Use your testing and learn how to treat SIBO. Both the hydrogen, methane and hydrogen sulfide types. And don't throw out the yeast with it either because they often go together and get that metabolite base 40% of the blood. Get it into a functional mode instead of a dysfunctional mode. Kaczor: Mm-hmm (affirmative). Mm-hmm (affirmative). Yeah. And I know, I will say that, you lecture and write a lot on the clinical aspects of this. So, anyone who wants further information can certainly start Googling you and find lots and lots to followup on. I do want to ask another question because this issue that we are in for the Natural Medicine Journal this month is a special on the microbiota and the microbiome. How do probiotics specially effect the gut-brain axis? Sandberg-Lewis: I don't know that we have enough yet to really have a great answer. Although, there are some docs out there that really have a strong handle on the strain specific effects of probiotics and people like Jason Hawrelak who is a ND and teaches at Western States and practices in Australia, he has totally got that covered. So, I would highly recommend looking at his website Jason Hawrelak, Hawrelak. But I mean, we know that there are studies that show that fermented foods significantly reduce anxiety, especially social anxiety. And there's a lot more research going on on strains, specific things that show that there are specific effects on anxiety and depression. But it's still really early so, I can't say I have a really good picture of that. When people ask me about probiotics, I usually say, "I don't know anything about probiotics". They don't believe me but, yeah. Kaczor: So, is it accurate to say that you advocate the whole foods diet, plenty of prebiotics in the form of fibers and resistant starches and things like that and then trust that if that is done well and consistently and then, of course if there is other treatments to kill undesirable bacteria etc. but complimenting ... I mean, the way to encourage the good bacteria is to give the prebiotics more in your view? Sandberg-Lewis: Well, the problem is a lot of my patients, because they have overgrowth, they can't tolerate prebiotics and fiber. So, when I first start working with them, we can't really use those things except very specific types. We know that partially hydrolyzed program seems to be actually beneficial for people who have overgrowth, sometimes used along with rifaximin in treatment of hydrogen SIBO and it increases the effectiveness of that. But, there's some GOS's that that may also be well tolerated. But that's a problem in the beginning because if you have overgrowth and then you feed them with a prebiotic, then it just increases symptoms and problems. So, it's a fine balance, it's a fine balance. But, yeah. I really encourage my patients to eat whatever fermented foods, probiotic foods that they tolerate. So, we use lactose-free, fermented dairy products, we use pickled items like kimchi or sauerkraut, the real stuff not the fake stuff. The refrigerated kind. Or homemade. And things like that. I think all traditional groups of people around the world have their own probiotic foods. Some of them pretty hard to even relate to, like haggis in ... where is that? Scotland. Where they eat the goat stomach that's fermented. Fish and rotten fish in the northern areas of Europe. There are some really interesting things you'd think, "Why the hell would people ever invent that food?" But these things have tremendous fermentative capabilities. And one thing that I'm sure NDs understand this but it comes up a lot with patients asking, they'll say, "So, you don't want me to eat any fermented food, right? Because I already have ... You want me on a low fermentation diet". And I say to them, "Well, no that's not what I want you to do". Unless you have a histamine sensitivity and you can't handle foods that are fermented, I want you to use those things because if you eat a high fermentation diet that has carbohydrates that are easily fermented, that produces gases. Hydrogen, carbon dioxide, maybe ethanol, methane, hydrogen sulfide in the gut and causes distention and pain and changes the stools and can cause bloating. But if you eat a food that is a fermented food, the gases have already come off into the atmosphere in the process of fermentation and now you're just getting all the bacteria and the great metabolites without the gas that causes the symptoms. I think that's an important differentiation. Kaczor: Well, yeah that's a great way to put it. To help them and us understand it a little bit. One last question, we'll end on a fun question, when you hear the term 'gut reaction to something', because we're talking about the gut-brain axis and someone says, "I used my gut" or gut instinct, gut reaction, what do you think? Sandberg-Lewis: Well, I'll bet physicians with different backgrounds have different ways of interpreting that but clearly if 90% of the input in the gut-brain axis is coming from the gut and if you think about it, if virtually every neuro peptide and GI hormone that's produced in the gut effects insulin and blood sugar and we know the brain suffers within minutes from blood sugar that's too low whereas the other organs may not care for quite some time and oxygen as well, of course, to the brain within three minutes. There are major effects on life and death related emotions that take place when the gut is feeling like something is wrong and it's gonna make more jittery molecules instead of more serotonin and gaba. And that's gonna have very rapid effects on the mood and on the functioning of the person's nervous system. Kaczor: Mm-hmm (affirmative). Alright well, I sure do appreciate the time you took to talk to us today about this. It is a huge topic and I am excited, as a naturopath that everything is coming back to a source, the GI tract, I mean and we've always been taught that we have to remedy the gut and get that in order before we can really keep someone in an optimal health state. So, sometimes that's harder than others and I do appreciate the time it took to enlighten us today with the gut-brain axis and it look forward to talking to you probably in the realm of gastroenterology again in the future. Sandberg-Lewis: Great, let's do it. Kaczor: Alright, take care. Sandberg-Lewis: Alright, bye.
“The CO2 problem is a waste management problem … If I were to dump my garbage in front of your house and you complained, I would say, ‘Now wait a minute. I’m 20% better than I was last year. I want a reward!’ … If you put it in this context, you see it immediately looks silly. The difference is, it really changes the way you think about the problem.” Ross and Christophe are joined by Dr. Klaus Lackner, the director of ASU’s Center for Negative Carbon Emissions (CNCE) and professor at the School of Sustainable Engineering. The CNCE is known for advancing carbon management technologies to capture carbon dioxide directly from the air in an outdoor operating environment. Today Klaus explains how he conceived of the windmill-sized structures that could scrub CO2 from the air and how these towers prove to be a more efficient solution than planting trees. Ross, Christophe and Klaus also discuss CO2 as a waste management issue, comparing the way society eventually addressed sewage with the current problem surrounding carbon emissions. Klaus offers his take on the feasibility of retrofitting coal plants for carbon capture, the politics of carbon sequestration, and the decreasing cost of carbon capture technology. Listen in to understand how putting a price on CO2 could balance our carbon budget and the role volunteers are likely to play in prompting government action. Key Takeaways [2:59] Klaus’ eureka moment around carbon sequestration Proposal to build tower that would turn wind energy into heat Realized structure could be 100X more efficient in reducing carbon footprint [7:22] The concept of a moisture swing Plastic coated in absorptive resin Pulls CO2 out of air when dry, releases when wet [8:53] Why trees aren’t an efficient method of sequestering carbon Scale problem (not enough land available to keep up with current emissions) Would compete with food production Klaus’ structures could extract 1,000X faster than trees Structures would not be in competition for agricultural land Excess CO2 could be converted to liquid fuel [14:28] How viewing CO2 as a waste management problem would change the game Comparison with sewage, must be properly treated and disposed of Either dispose safely or not make in first place Air capture functions like street sweeper Can’t just make less CO2, must collect what put out Oil industry injecting CO2 in ground for EOR is not enough Far more opportunity to store carbon than can be made from coal, oil and gas [20:46] Klaus’ work around diffused carbon capture Carbon capture industry can never be carbon neutral Must be balanced through removal [22:33] Why Klaus is skeptical of the proposal to retrofit coal plants for carbon capture Coal plants not designed for this (inefficient, cheap) Price would jump, not economically viable Coal can’t compete with natural gas as it is Old coal plants will become stranded assets [26:26] Small power plants vs. large power plants Bigger not always better, consider cost and scale Reduced risk in small plants that don’t last If assumptions incorrect, can pivot after two years [30:34] Klaus’ insight around the politics of carbon sequestration Similar to sewage discussion in 1800’s Trigger event necessary to spur change Dire economic consequences if unprepared [32:00] The role of volunteers in prompting government action Volunteers can lead way, i.e.: recycling movement [33:53] How to foot the bill for carbon sequestration Take one ton from ground, must demonstrate that one ton put away May motivate to replace carbon with renewables Cannot predict if cheaper to bury carbon or replace [40:01] The alarming rate of increasing carbon emissions 280 ppm before Industrial Revolution 300 ppm by 1900 Currently 400 ppm, increases by 2-3 ppm per year Will reach 450 ppm in 15-17 years CO2 emissions grow with economies [45:06] The decreasing cost of carbon sequestration Climeworks went from $600/ton to $400/ton First of kind always expensive, technology can drive costs down Klaus believes $60/ton is possible Automation makes revolutionary change possible Could collect thousands of tons of CO2 on few acres of land [50:11] Klaus’ take on the future of the air capture industry Transition to waste management paradigm Develop like other technologies (more affordable) Volunteers to spur change (i.e.: individuals, corporations) Air capture one of many players in game Price on CO2, world could balance carbon budget Cannot solve problem by stopping growth Connect with Ross & Christophe Nori Carbon A List Resources ASU Center for Negative Carbon Emissions Klaus Lackner, PhD IPCC Report on Carbon Dioxide Capture and Storage Sleipner CO2 Storage Climeworks
"90% of information transmitted to the brain is visual, and visuals are processed 60,000X faster in the brain than text." [Sources: 3M Corporation and Zabisco] We continue with our theme of “Creating Content” as a sales professional. Today we focus on how to create an InfoGraphic. Visual content drives engagement. In fact, according to research conducted by Simply Measured, just one month after the introduction of Facebook timeline for brands, visual content — photos and videos — saw a 65% increase in engagement. You can take advantage of this same approach as a sales professional by creating your very own InfoGraphic to illustrate your knowledge and expertise while helping simplify complex topics for your target audience. We provide three tips on how to create and share an InfoGraphic to elevate your status as a thought leader and go-to-specialist in your field. If you want to take advantage of the power of visual content to improve your sales prospecting game, then you will want to listen to this episode.