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This episode is brought to you by Levels, Bon Charge, and Ollie, For years, many have believed that cancer is primarily genetic or just bad luck, but emerging research suggests we have far more control over our risk than previously thought. Dr. Thomas Seyfried's groundbreaking work reframes cancer as a metabolic dysfunction, focusing on its root cause rather than just treating symptoms. While controversial, this approach offers new hope for both practitioners and patients seeking alternative strategies for prevention and treatment. Today on The Dhru Purohit Show, we're bringing you a special compilation episode featuring Dhru's conversations with Dr. Thomas Seyfried and experts from the Hippocrates Research Foundation, a nonprofit dedicated to continuing Dr. Seyfried's work by educating cancer patients on metabolic-based treatment approaches. Dr. Seyfried explores the role of oxidative stress, mitochondrial health, and glucose in cancer development and progression, along with his research on ketogenic diets as a promising solution to correct these imbalances. Den Stacey shares his journey of seeking guidance from the Hippocrates Research Foundation—ultimately becoming cancer-free. The Hippocrates Research Foundation team—Daniel Orrego, Dr. Gregory Howard, and Dr. Michelle Howard—discuss their research and their approach to guiding cancer patients by implementing a protocol designed to starve cancer while fueling the body. Dr. Thomas Seyfried is an American professor of biology, genetics, and biochemistry at Boston College. With over 150 peer-reviewed publications, his research focuses on the mechanisms driving cancer, epilepsy, and neurodegenerative diseases, as well as the role of calorie-restricted ketogenic diets in their prevention and treatment. He is the author of Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer and serves on the editorial boards of Nutrition & Metabolism, Neurochemical Research, Journal of Lipid Research, and ASN Neuro. In this episode, Dhru and his guests dive into: The role of mitochondrial dysfunction in cancer (04:05) The promise of the ketogenic diet and its impact on cells (09:58) How the ketogenic diet cuts off cancer's fuel sources (20:37) Den Stacey's email about his experience with Dr. Seyfried's protocol (26:54) The Press-Pulse protocol used in Den's treatment (30:25) The role of stress reduction as a key part of the protocol (35:31) The benefits of hyperbaric oxygen therapy (38:53) Why pharmaceutical drugs and diet should be used in concert (40:47) What an ideal cancer treatment team looks like (46:31) Testing and evaluating the protocol in real-world cases (56:39) Recognizing the success of the case study and the next steps (59:42) Final thoughts (01:02:01) Also mentioned: Full episode with Dr. Thomas Seyfried Full episode with Den Stacey This episode is brought to you by Levels, Bon Charge, and Ollie, Right now, Levels is offering my listeners an additional 2 FREE months of the Levels annual Membership when you use my link, levels.link/DHRU. Make moves on your metabolic health with Levels today. Right now, BON CHARGE is offering my community 15% off; just go to boncharge.com/DHRU and use coupon code DHRU to save 15%. Want to give your dog the best in clean eating? Take the online quiz and introduce Ollie to your pet. Right now, Ollie is offering 60% off your first box of meals when you subscribe today! Just head to Ollie.com, use the code DHRU and you'll get 60% off your first box of meals in your subscription. Learn more about your ad choices. Visit megaphone.fm/adchoices
Welcome to another episode of the Health Upgrade Podacat!Today we talk with Dr. Thomas Seyfried, a leader in cancer metabolism research. He shares his amazing discoveries about how cancer is linked to metabolism, starting from his early work with epilepsy and ketogenic diets. He explains how problems in mitochondria and cancer cells' reliance on fermentation challenge the usual genetic view of cancer.We explore how therapeutic ketosis and metabolic therapy could change cancer treatment. Dr. Seyfried highlights the importance of cutting glucose and glutamine to target cancer cells while protecting healthy ones with ketosis. He also introduces the "Press PULSE" method, a powerful approach backed by real-life cases and ongoing research.We also discuss how modern diets may increase cancer risks and explore the importance of gut health and our evolutionary diet. This conversation offers a new way to look at cancer, focusing on metabolism and diet as key tools for better health.Don't miss this enlightening episode that could reshape your understanding of cancer treatment! Tune in, and feel free to share with anyone who's interested in innovative, holistic approaches to health. Dr. Navaz HabibEmail: podcast@healthupgraded.comFacebook: https://www.facebook.com/DrNavazHabib/Instagram: https://www.instagram.com/drnavazhabib/LinkedIn: https://ca.linkedin.com/in/drnavazhabibJP ErricoLinkedIn: https://www.linkedin.com/in/jp-errico-097629aaDr. Thomas SeyfriedWebsite: https://tomseyfried.com/
Miriam encountered cancer when her son was diagnosed in 2007 and now uses her experience and knowledge through this tough time to help others while providing inspiration and guidance to find what works for them individually in this battle. Bio: Miriam Kalamian is a nutrition educator, author, and consultant specializing in the ketogenic diet for cancer. In her work with hundreds of people, she has personally witnessed the life-changing effects of this powerful diet therapy, starting with her son's journey in 2007. Time Stamps: 8:41 – Miriam’s story and her son’s encounter with brain tumor 11:09 – Her conversation with Dr. Thomas Seyfried & Ketogenic Diet 16:34 – Coming across Charlie Foundation 19:52 – Orchestrating cancer treatment and factors that could impact tumor growth 22:42 – Care oncology and repurposing drugs 25:13 – Press-Pulse strategy of cancer cell annihilation 28:20 – How do you prioritize and add healthy routines and intervention? 34:22 – Where do you find reliable resources for cancer and keto? 42:56 – Concerns with standard of care guidelines 50:31 – Modern companies that are using alternative methods towards health goals 54:31 – Protein Intake and challenges with veganism and Keto 1:07:16 – Why aren’t we getting a grip on cancer? 1:16:34 – Why do cancers return later? 1:21:22 – What kind of research do we need more for cancer? 1:22:24 – What potential technologies or research are coming out for cancer? 1:26:19 – Message for people who are fighting cancer 1:29:53 – Final Plugs Guest Links Website: www.DietaryTherapies.com Facebook: Miriam Kalamian Twitter: DietaryTherapy YouTube: Miriam Kalamian Book: Keto For Cancer, Metabolic Therapy as a Targeted Nutritional Strategy Ketogeek Links: Shop Energy Pods Amazon: https://www.amazon.com/Ketogeek-Chocolate-Energy-Organic-Vanilla/dp/B07B88S36J Ketogeek Ghee on Amazon: https://www.amazon.com/dp/B07B29HM3D Ketogeek Merchandise, Ghee & Energy Pods: https://ketogeek.com/collections Ketogeek Newsletter Sign Up: https://ketogeek.com/pages/sign-up Shop Energy Pods: https://ketogeek.com/collections/energy-pods Wholesale: https://ketogeek.com/pages/wholesale
Dom digs deep into the research and application of ketogenic diets, exogenous ketones, hyperbaric oxygen treatment, and treating cancer with a metabolic approach. Plus, we lost track of the number of n=Dom experiments mentioned in this episode. We discuss: Dom’s early medical training in hyperbaric chambers [7:00]; Effect of ketones on cancer cells [20:00]; Ketones and oxygen toxicity seizures [32:00]; HBOT & its many applications [40:00]; Ketones, MCTs, and exogenous ketones [59:15]; How ketones affect blood glucose [1:20:00]; Ketone esters, salts, enantiomers vs. racemic BOHB [1:38:00]; Dom’s ketone tolerance test [1:56:00]; The metabolic management of cancer with a Press-Pulse approach [1:59:45]; and More. Learn more at www.PeterAttiaMD.com Connect with Peter on Facebook | Twitter | Instagram.
Is Cancer a Metabolic (Mitochondrial) Disease? Our guest on the OPP today, Dr. Thomas Seyfried says it is. Dr. Thomas Seyfried is a leading cancer researcher, Biology professor at Boston College and author of the book Cancer as a Metabolic Disease. His work focuses on epigenetic and metabolic nutritional therapies for neurological and mitochondrial diseases. According to Dr. Seyfried, cancer is a mitochondrial metabolic disease. His Press-Pulse protocol of ketosis, fasting, and Hyperbaric Oxygen Therapy (HBOT) created with colleague Dominic D’Agostino is producing amazing results in animals, dogs, and people. On today's show, we explore: Why Dr. Seyfried thinks genetic tests are a waste of time & money Why neuroinflammation should scare you (Hint: it's linked to almost every major disease) How cancer could be single disease with a single cause, and a single cure Why calories restriction - and fasting - signals our healthy cells to improve themselves How ketosis starves cancer cells and helps heal the body Why protecting our mitochondria may be our best method to reduce our risk of cancer How Dr. Seyfried and Dominic D'Agostino linked up to create the Press-Pulse method of starving cancer with ketosis, then destroying it with Hyperbaric Oxygen Treatments (HBOT) The frustrating truth about why the scientific and medical communities are not rushing to fund studies and implement these treatment protocols Dr. Seyfried is a brilliant man who is asking the right questions and taking great strides to advance our understanding of cancer and health in general. You'll hear and see more of Dr. Seyfried's Press-Pulse anticancer treatments in the book Tripping Over The Truth and the forthcoming Dog and Cancer Series. We're honored to have him on the OPP, and excited to share this information with you. Share this episode, tag us in your post, and you'll be entered to win a signed copy of Dr. Seyfried's Book "Cancer as a Metabolic Disease"
Episode 164: Dominic D'Agostino, PhD of the University of South Florida discusses his lab's research onto various treatment therapies for cancer including nutritional ketosis, hyperbaric oxygen therapy and metabolic drugs. Dr. D'agostino is an Assistant Professor at the College Of Medicine Molecular Pharmacology & Physiology at the University of South Florida. The primary focus of his laboratory is developing and testing metabolic-based therapies, including ketogenic diets, ketone esters, ketone supplements and metabolic-based drugs. His research also explores the use of these metabolic therapies for a broad range of disorders linked pathophysiologically to metabolic dysregulation, including seizures, neurological disorders, wound healing, muscle wasting and cancer. The laboratory uses in vivo and in vitro techniques to understand the physiological, cellular and molecular mechanism of metabolic therapies. In This Episode We Discuss: Cancer as a metabolic disease Potential mechanisms of action for ketosis being a beneficial metabolic state in cancer patients Ketosis, calorie restriction, hyperbaric oxygen therapy and metabolic drugs as adjunct therapies in cancer treatment Possible future avenues of research What research needs to be done for this research to become seen more in front-line clinical practice Barriers to implementation
Guest // Thomas Seyfried, PhDHost // Toni Bark, MDHalf of men and one-third of women will receive a cancer diagnosis sometime during their lives. Increasingly, more patients are declining conventional treatment. They are interested in a different kind of approach to cancer management and prevention.. one that is more cutting edge and incorporates the latest research.If we can understand what cancer is, what feeds it, and why metastasis happens, then we can find and apply more effective strategies to shrink (and hopefully eliminate) tumors.Meet Professor Thomas Seyfried. He is a biochemical geneticist who has been investigating the lipid biochemistry of cancer for thirty years. His pioneering research expands on Otto Warburg’s groundbreaking theory that cancer is a disease of energy metabolism. With this framework, he’s able to explain the relationship between cancer and inflammation, vascularization, cell death, drug resistance, and genomic instability. Discussion topics during today’s show include:How does this view differ from the direction in which much of current research and funding is heading? (i.e., genetics)Is the controversy largely a matter of cause and effect (i.e., mitochondrial respiration and genetic damage)?What has been the response of the scientific community?Where is the research heading? (i.e., mouse to man, clinical trials?)What is the ketogenic diet and how is it implemented? How does this differ when applied to children?What is the Press-Pulse metabolic strategy for cancer management?If you have questions, be sure to send them before the show or meet up with us on the blog afterwards to discuss.Thomas Seyfried, PhD focuses on gene environmental interactions related to complex diseases, such as epilepsy, autism, brain cancer, and neurodegenerative (the GM1 and GM2 gangliosidoses) diseases. He investigates many of these diseases from the perspective of, genetics, lipidomics, and energy metabolism. Tom received his Ph.D. in Genetics and Biochemistry from the University of Illinois, Urbana, in 1976. He was an Assistant Professor in Neurology at Yale University School of Medicine. Tom has received awards from the NIH, The American Society for Neurochemistry, and the Ketogenic Diet Special Interest Group of the American Epilepsy Society. He was Chair, Scientific Advisory Committee for the National Tay-Sachs and Allied Diseases Association and serves on several editorial boards, for Nutrition & Metabolism, Neurochemical Research, the Journal of Lipid Research, and ASN Neuro. Read more about his work here.