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Returning guests Cecilia Conti and Josh Reinhold join Torie to eviscerate the cultural climate's pathetic answer to a feminist take on an erotic thriller, THE HOUSEMAID (2025). Starring everyone's favorite MAGA-loving bimbo, Sydney Sweeney, the phenomenally talented Amanda Seyfried, and a lesser-Hemsworth-coded hunk named Brendan Sklenar (who Josh looooves), this film undoubtedly caters to the true crime-obsessed, Colleen Hoover-reading, Lifetime™-loving audience. Featuring disappointingly little sex, atrocious clothing, unnecessarily gratuitous violence, and awful one-liners, this "for women, by women" film fails to meet its intended goal of feminist rhetoric. Despite a truly bang-up performance from Amanda Seyfried, it barely even meets the criteria for a solid hate-watch. Amid the discourse, Torie struggles not to sound like a misogynist discussing Sydney Sweeney's most famous attributes, and everyone fails (again and again) to correctly pronounce Seyfried.
In this episode, Cheryl sits down with Brad Pitzele to unpack a long and complicated health journey that began with early autoimmune symptoms and escalated into psoriatic arthritis, debilitating fatigue, and eventually melanoma linked to immunosuppressive treatment. Frustrated by a system that offered only escalating medications and limited answers, Brad began an intense period of self-experimentation and research. His turning point came after a Lyme disease diagnosis, one that helped connect years of seemingly unrelated symptoms. This ultimately pushed him deeper into understanding the root causes of chronic illness, especially the role of mitochondrial dysfunction and inflammation. From there, the conversation shifts into the tools that helped Brad reclaim his health, including exercise with oxygen therapy (EWOT) and red and near-infrared light therapy. He explains how both approaches work at a cellular level to improve oxygen delivery, support mitochondrial function, and reduce inflammation. Thseare are all mechanisms that have implications for conditions like chronic fatigue, autoimmune disease, multiple sclerosis and even cardiovascular health. This episode is a deep dive into resilience, curiosity, and the power of continuing to search for answers when conventional paths fall short, offering both practical insight and hope for anyone navigating complex or unexplained health challenges. Connect with Brad at One Thousand Roads. Disclaimer: Links may contain affiliate links, which means we may get paid a commission at no additional cost to you if you purchase through this page. Read our full disclosure here. Takeaways Chronic symptoms do not always have clear answers and standard care often focuses on managing symptoms rather than addressing root causes Mitochondrial health plays a central role in energy, recovery, and overall resilience and when it is compromised nearly every system in the body is affected Inflammation and low oxygen levels go hand in hand, creating a cycle that can worsen chronic illness over time Exercise with oxygen therapy works by increasing oxygen delivery to tissues and may support energy production and reduce inflammation Red and near infrared light therapy may enhance mitochondrial function by increasing cellular demand for oxygen and boosting energy output Combining oxygen therapy with red light can create a complementary supply and demand effect at the cellular level Healing from complex or chronic conditions is rarely quick and consistent cumulative inputs over time matter more than short term fixes Self advocacy and curiosity are critical when navigating unexplained health issues or when conventional approaches fall short Small improvements over time can rebuild momentum and hope even before full recovery is achieved Simple inputs like oxygen, light, and movement can have powerful effects when applied consistently and strategically Watch on YouTube Disclaimer: Links may contain affiliate links, which means we may get paid a commission at no additional cost to you if you purchase through this page. Read our full disclosure here. CONNECT WITH CHERYL Shop all my healthy lifestyle favorites, lots of discounts! 21 Day Fat Loss Kickstart: Make Keto Easy, Take Diet Breaks and Still Lose Weight Avaline Wines, Tested and Clean, Sugar Free Drinking Ketones Wild Pastures, Clean Meat to Your Doorstep 20% off for life Clean Beauty 20% off first order DIY Lashes 10% off NIRA at Home Laser for Wrinkles 10% off or current promo with code HealNourishGrow Instagram for daily stories with recipes, what I eat in a day and what’s going on in life Facebook YouTube Pinterest TikTok Amazon Store The Shoe Fairy Competition Gear Getting Started with Keto Resources The Complete Beginners Guide to Keto Getting Started with Keto Podcast Episode Getting Started with Keto Resource Guide Episode Transcript Cheryl McColgan (00:00)Hey everyone, I’m Cheryl McColgan and today I am joined by Brad Pitzley and we are going to talk about some of his health history. He has a really interesting background with some challenging diseases and scenarios that he went through. And you know, like many of the guests on the HealNursery podcast, he just has a health journey that he wants to share with people and kind of what ended up actually helping him. Because so often people go down these roads with different conditions and they just have a lot of trouble finding out number one what it is, number two if there’s anything that can help them feel better or how to treat it. And so I think Brad’s going to have a lot of really interesting things to share with us today. So Brad, if you could just maybe start by, I don’t know how far in the way back machine you want to go, but kind of just, you know, give us a little bit about your health journey. And as we go along, I’m sure I’ll have some kind of questions to fill in for everyone. Brad Pitzele (00:50)Yeah, I had weird health things going on since grade school. I was diagnosed with psoriasis, but then I had other weird things that just kind of came and went. We’d go to the doctor, they’d give it a label. It would last for a while. There was no treatment for said label and then it would kind of just disappear and then I’d move on with life and then a year or six months or whatever, something else might pop up. But it really kind of started to come to a head. Um, probably around 2010 or 11, I started to develop autoimmune arthritis, what was considered psoriatic arthritis, which is, it’s basically like rheumatoid arthritis, but it’s what you get with psoriasis. Um, and they started to test all sorts of different drugs on me. The first sets didn’t work. Then they put me on, um, some immune suppressive drugs. They gave me relief for like maybe six months and they’d start wearing off and they would double the dose and they’re. I was kind of worse off when it wore off and then it would kind of bring me up a little bit. And then was kind of like I was taking a stair step into, you know, into a worse and worse place. And I was on those drugs for probably about two years. And then I developed melanoma. And that’s one of the side effects of the drugs is it’s got a high risk of cancer and specifically melanoma. So that was kind of a, a jumping off point for me. I, during that period, I also started to develop weird other symptoms. Like I started to get stiffness in the back of my legs. had tremendous brain fog and energy issues. had pain in my feet and I would take this back to the rheumatologist and I’d be like, this is, is this part of the, this disease? assume. he was like, no, that’s not part of the disease. And I was kind of shocked and like, well, it feels like part of the disease. It’s kind of, you know, it’s just. Cheryl McColgan (02:38)All right. Brad Pitzele (02:41)another symptom of whatever’s going on with me. But he didn’t really acknowledge that. And then when I got cancer, I went back to him and I was like, Hey, you know, I’m really afraid I’m like, if I keep taking these drugs, more risk of cancer. I don’t take these drugs. I, you know, I die, cripple crumpled up in a ball in the corner, so to speak. And he was kind of like, no, I don’t think that’s going to happen. Yeah. I think we’re just going to try another drug in the, the, the same category. And that was like, just started having alarm bells in my head. Just started shouting at me. was like, either path feels like it’s very bad. And I was a, I had a young children at the time. I was a relatively new father and that was even more scary. I was kind of the single income in the household. And I just started like, I’m like, what happens if these things happen to me to not just me, but my family. and that’s kind of when I started jumping off and like doing my own research and trying to figure out what I call a third path for because neither of those really made sense to me. Cheryl McColgan (03:40)those both sound like not very good options. I’m just kind of curious when you were going back to the doctor with these things, kind of two questions here actually. One, and I think I already know the answer, but one, were drugs the only answer that this doctor was able to give to you? And secondly, I think having the cancer being a known side effect of the drug is really interesting. you ever talk about what the mechanism there is or anything to know about that just for people with curiosity? Brad Pitzele (04:07)Yeah, so yeah, mostly it was drugs. He did also offer me injections of steroids into some of my joints. He was very skilled at it, because he said it was gonna be very painful. It wasn’t that painful, but steroids turn off your immune system. And it’s the same thing with some of the drugs I was on. One of them was a… I won’t call brand name, but it was a TNF inhibitor. TNF stands for tumor necrosis factor. And it’s basically in a component of our immune system. And so there was some research done and they found that if they turned off that component of your immune system, hey, the pain and symptoms go away. Unfortunately, as the name alludes to, it kills tumors. when you turn it, we all have cancer in our Cheryl McColgan (04:49)Yeah Brad Pitzele (04:52)body. Like right now as we speak, everyone has it. It’s just our immune system is able to kill it off and so it never really gains a foothold. But once you start tipping the balance of the scales, obviously, you know, it can run amok. And that’s what happened in my case. Cheryl McColgan (05:08)Yeah, very interesting. also it just brings up so many other questions that I’ll have to go down a rabbit hole after we’re done with our conversation. But so you had these things, you didn’t have good relief, you were still having symptoms, then you got cancer. And I assume obviously you had to get treated for that at that point. Was that really the turning point for you to just be like, I’ve got to find some other way to manage this? How did how did things go from there? Brad Pitzele (05:30)Yeah, it was, and I’m not gonna tell you it was a fast turn for me. It took me several years. But I mean, from there, I just started reading anything I could. I read books, I was out on the internet, I was in chat groups talking to other people who had similar symptoms, Facebook groups, Googling on PubMed, looking at research, so many rabbit holes I ran down. I was joking, I’m recovering engineer. ⁓ I got my undergraduate in mechanical engineering, so I’m very analytical by my nature, I suppose. Research didn’t scare me, and I just was reading anything I could. I wasn’t gonna… Cheryl McColgan (05:55)You Brad Pitzele (06:07)You know, wait for them to find something in the research and then try to translate it 20 years later. Like that does me no good. and I tried everything. I did a lot of self experimentation, everything from complete changes of diet, supplements, so many, mean, different modalities, all sorts of weird stuff. Sometimes my family looked at me pretty good side, I when they saw some of the stuff I was doing. but you know, when you’re, when you’re really desperate and. things are getting worse and worse. And particularly when you also feel this responsibility and obligation to your family, you just, it’s not even just about you. You’re like, what do I do? I like, I’m gonna disappoint all these people and life is not gonna be good for them. I just told myself, I’m not allowed. know, like this is absolutely not allowed. This is not gonna happen, but it kept happening for a few more years. And then, I ended up at a doctor’s office and he tried all sorts of things. Nothing was working. He was an MD, but he was non-insurance, so was integrative. And he was trying all sorts of alternate modalities on me. Even the things he was sure were gonna do anything, nothing was doing anything. He’s doing testing on me, nothing was popping. And then he suggested I do a Lyme disease test. I remember thinking, I’m like, doctor, I don’t have Lyme disease. I’m like, I’ve never been bitten by one of these ticks. I’ve never had that bullseye rash thing. I’m thinking to myself, I don’t have that. But I was kind of like, you know what? And it was expensive test at the time. It was like 500 bucks. Insurance didn’t pay. But I was like, you know what? I’m gonna pay the 500 bucks. I’m gonna do the test so he can see it’s negative and we can get him off this Lyme thing. We can get to the real deal because it’s not Lyme. And sure enough, it came back that I had Lyme disease and one of its co-infections called Bartonella, which is the infection that causes cat scratch disease as well. And I was so shocked. went back to him. was like, doc, what’s the chances this is a false positive? I don’t think I have it. And he was like, Brad, it’s a urine PCR, which means you have the DNA of those bacteria in your urine. What do you think is the chances it’s, it’s false positive? I’m like, got it. Cheryl McColgan (08:12)Not. Brad Pitzele (08:14)And that’s when it finally started to hit. ⁓ Cheryl McColgan (08:16)Well, just for people that aren’t familiar, I think everybody’s kind of heard of Lyme disease at some point, maybe Bartonella, but what did that kind of mean to you at the time? Like I’m sure once you got that diagnosis, you wanted to learn more about it. Were you thinking that that explained some of the things that you had up to this point or how did that mesh into the whole symptom profile? Brad Pitzele (08:36)Life disease is incredibly challenging. for a variety of reasons. One, it’s very difficult to get under control. There’s a lot of folks in America and across the world, quite frankly, suffering with it right now. The other reason it’s tough is there’s not a lot of doctors willing to treat it. There’s this whole stigma about it. What makes it particularly difficult is there’s this question on if it actually exists in some doctor’s head. It’s like the weirdest thing in the world. We know there’s this infectious agent, we know it infects humans, and yet when a human comes to the doctor and says, I’ve been infected by it, they’re like, are you sure? And so you kind of get, I think the term I hear often is medical gas lit. And on top of that, doctors, for legal reasons, often don’t want to touch it. So my doctor didn’t want to touch it. And he was like, look, you have to go to a Lyme specialist three hours away. I recommend him as best I can. And it was a long waiting list to get into this doctor’s office. And while I was waiting, just… I was relentless, you I just couldn’t sit here and let myself deal with all this. It was a three month wait. And so I just started reading voraciously on Lyme disease to your point. was reading all sorts of research. I was reading books on it, a lot of books on the, like the science and what was happening to your body mechanically. And it was actually pretty eye opening because when I started to read all these symptoms, I was like, I started to piece together all these pieces, the puzzle that happened to me in my childhood, ⁓ things that happened Cheryl McColgan (10:12)Mm. Brad Pitzele (10:13)more recently, things that the rheumatologist couldn’t explain, but now we’re clear as day what was going on. And so the jigsaw puzzle started to fall into place for me. So it was kind of an epiphany from that perspective, yeah. Cheryl McColgan (10:29)Yeah, that’s got to be the waiting had to be one of the hardest things, I’m sure. then once you finally got to him, did he because he was specialized in Lyme specifically, did he have any solutions for you? Or then was it somewhere that you still had to go to go down the road? Brad Pitzele (10:42)No. You know, the disappointing thing is, I ended up, the whole family was diagnosed with Lyme disease, not just me, my children and so forth. So we all carted in the car down three hours from, I live in Dallas area down in Austin. He had a lot of things to say to us. It was kind of stuff I’d already read. Most of it I’d already tried. know, supplements I’d already run through myself and like it became cost prohibited both the time and the visitation and we just didn’t get anywhere. So we probably visited him. five or six times and then I was like, okay, well this is not, know, and was, each time it was kind of clear, like his tools were somewhat limited. And so then it was time to kind of, while I was doing his stuff, I was also just actively experimenting. was, you know, was a, you know, a test dummy every set, every second of it, because again, you know, you just can’t wait, you know, come back in two months. You’re like, if this thing doesn’t work in a few weeks, I got to, I’ll keep doing it, but I’ll add other things. See where I go. Cheryl McColgan (11:46)Right, well, I’m sure once you knew that your whole family had this issue that probably made you want to solve it even more, not that it wasn’t enough for you to solve it for yourself, but now you’ve got other people in your family that you want to feel well, you know? Brad Pitzele (11:53)Yes. Absolutely, absolutely. was definitely set heavy on my mind. Just I didn’t want the kids to have to go down this path. Cheryl McColgan (12:06)So this kind of leads us into this whole backstory into the sign that’s behind your head right now, 1000 roads, because you kind of did that many roads to get here, right? And so what did you come across? I thought that was like one of the best business names I’ve ever seen, the way, knowing the backstory. But anyway, what was it that you found in the research or what led you to kind of, there’s a couple of things that did end up helping you, which is awesome, because I think now we’re going to share this with people because Brad Pitzele (12:16)Yeah, that’s right. you Thank you. Cheryl McColgan (12:35)Like you said, there’s plenty of people out there with Lyme disease. There’s plenty of people out there with unexplained illnesses or things that are affecting them. And, you know, there are some interesting tools that do work, worked in your case. So how did you end up finding what actually ended up working for you? Brad Pitzele (12:50)Well, I eventually started doing a lot of research on all sorts of things. And one thing that stuck with me was mitochondrial health. I hear more and more folks talking about it in recent years, which is great, but this is probably about a little 10, 12 years ago. It really wasn’t a well-spoken about area. the more I researched about mitochondrial health, the more I realized this is at the root of everything. So for your listeners, the mitochondria are this little organelle, this little subset inside all of your cells that produce the energy. And they’re extremely fragile. And when they get damaged or they’re not working efficiently, nothing works efficiently because everything takes energy, right? Us talking takes energy, thinking takes energy, moving our muscles, our organs working take energy, repair our immune system, all of it. And so often when you’re dealing with chronic health conditions, particularly when you’re dealing with an infectious agent or even cancers, they go after our mitochondria. because they kind of take the power down in the system and that gives them a leg up on our immune system and our defenses and it allows them to kind of I would call it just burrow deeper into our biology and you know shift the biology to be more favorable towards whatever that is. So for me it that was kind of an epiphany and I delved into a couple tools and the first one was something called exercise with oxygen therapy. also known as EWOT, E-W-O-T. No one was really talking about it. It was kind of the small little thing, not a lot of information out there. And then there was a second one, more folks have heard of today, which is red light therapy, and really red and near infrared light therapy. And they both work through mechanisms that help the mitochondria restore itself. Cheryl McColgan (14:45)Yeah, the exercise, I was looking at the photo on the website of the EWOT contraption and I’m kind of having a hard time conceptualizing. think what, and actually before we go into that, let’s address this other question that came up in my mind when I was looking at the contraption, because I’m like, okay, the thing that most people are probably somewhat familiar with nowadays is a hyperbaric oxygen chamber. And that is used in cancer treatment. think it was, Dr. Seyfried has this thing, and you might be familiar with him just like. through your mitochondrial research, but it’s called like a press pulse thing that they use with cancer patients. And it has to do with ketogenic diet, because you’re starving the cancer of sugar. And then also this hyperbaric oxygen therapy. That’s, that’s all just kind of a weird aside for people that are hearing this, it really has nothing to do with this conversation. But it’s interesting to look up. But for your thing, the hyperbaric works in one way. And I think people like you can visualize it, because you go in and you kind of just lay down. And that’s what it is. But this And when people go to the website, they’ll see it. It’s kind of, looks like a big balloon or a box. So guess I’m having trouble kind of conceptualizing how do you even use that or, how do you exercise with that? That’s a very long winded question, but hopefully we’ll get there. Brad Pitzele (15:47)Yeah. Sure. Well. Yeah, that’s great. So I think it’s two questions. What is it? How does it work sort of thing? Exercise with oxygen therapy at its principles really simple. It simply involves doing any sort of exercise, preferably something that gets your heart rate up, generally cardiovascular exercise, while wearing a mask and breathing near pure oxygen, so about 93 % oxygen. So to your point about how does the contraption or the EWATS system work, it works as, it’s like this, there’s actually a device called an oxygen concentrator that can produce an endless supply of oxygen. You plug it into the wall and you flip the switch and it takes the oxygen in your room, which is probably at like let’s say 21 % at sea level, and it purifies it to 93 % oxygen by separating out the other gases, the nitrogen and the argon. which is great, but these machines that you can plug into your wall, your home outlet, they produce only five or 10 liters of oxygen in a minute. And when you exercise, you can easily use 50 or 60 liters in a minute. So to get a 15 minute session in, you can easily use 900 plus liters of oxygen. And that machine’s only putting out at the best 10 liters of it. And so every minute. And so what we do is we take that machine and we fill a large reservoir to a thousand liters. So think of it as about six feet, five and a half, six feet squared. It looks like a big pillow. And we fill that thing with oxygen. Now to like dimensionalize this for folks, a thousand liters of oxygen is similar to the amount of oxygen you’ll breathe in an entire day. And we’ll fill this, this, you know, bloom, what we call a reservoir with oxygen. And then we’ll attach a hose with a mask on the end of it. Put the mask on and you just breathe out of that reservoir. of water. So again, in that 15 minutes, you can take in a whole day of oxygen. It’s really a massive amount. Now, how does it compare to hyperbaric oxygen? That’s a really good question. Hyperbaric oxygen, at its core, what you do is you get inside of a chamber, they pressurize it, and that forces more oxygen through your lung membrane and into your blood. Now, Once it gets past your lung membrane and into your blood, your, what happens in hyperbaric oxygen is it goes not just into your red blood cells, because if you look at your red blood cells right now, which are the parts of your blood that are designed to carry oxygen, they’re at capacity. Like you can put a little pulse oximeter on your finger and it’ll say 99 % or 100 % or 98%. And so there’s not room for more oxygen, but what hyperbaric does, and EWAT does the same thing, is it actually forces oxygen into your blood plasma. Now blood plasma is this clearish brown liquid, it’s effectively water plus plus, that all the red and white blood cells ride on. And so it can actually turn that into an oxygen carrying vehicle inside your blood, something that normally doesn’t carry very much oxygen. And that’s through a process called Henry’s Law, which goes beyond human biology. It’s really just a chemistry law that says, you take an insoluble gas and enforce it on top of an insoluble liquid, it’ll force the gas to go into solution. In this case, the gas is oxygen and the liquid is blood plasma. Now, in hyperbaric oxygen, the body tries to get back into balance. It notices there’s a surplus of oxygen in the blood. And so your body tries to regulate, go back to homeostasis by using something called vasoconstriction, which means your blood vessels constrict. They get smaller to allow less of that oxygen through. So your body is naturally fighting against delivering that oxygen. In spite of that, you deliver a large dose of oxygen to the tissues. In IWA, what we do is we come to the opposite. Instead of using pressure to force more oxygen into and through your lungs, we use exercise to pull it through. So when you start exercising, your body immediately recognizes that it needs more energy. And the gating factor in producing more energy is oxygen. We all in this Western world generally get enough food. It’s just we’re… When you’re exercising, there’s not enough oxygen. So when it notices this, you have all these physiological changes, right? You start breathing faster and deeper. Your lung membrane actually thins out to allow more oxygen to pass through. Your heart starts beating faster. Every beat is deeper. Your blood vessels actually dilate. They actually open up to allow larger blood flow through them. And then when you exercise, naturally, actually, your blood pressure goes up. And most of us think, no, high blood pressure is bad, but in exercise it’s actually really good because the more pressure inside your blood, that differential between the pressure in your circulatory system and the tissues is like a driving force that drives the oxygen out of the blood and into the tissues. we do EWAT, we’re taking advantage of all those physiological changes to allow us to take in oxygen very quickly and deliver it deeply into the tissues. in a 15 minute EWAT session, you could take in as much oxygen as you would in a hyperbaric session in 90 or more minutes. It’s really quite a large dose. Cheryl McColgan (21:09)Wow. then what about, so how does that affect the mitochondria? Does it just give them more energy and kind of helps them repair quicker? Or what’s the connection between mitochondrial health and the EY? Brad Pitzele (21:16)Thank This is actually the really fascinating part. And this is the thing that really got me more interested in it. EWAT was founded actually in the 1960s and 70s. There was this prolific inventor named Manfred von Arden. He was a German physicist and inventor. He invented the scanning electron microscope. He helped commercialize television technology in the 1930s. And he got interested in oxygen in 1960s and 70s because there was a gentleman named Warburg in the 1920s who had proven that he could take any cancerous cell, any regular cell and turn it into a cancerous cell simply by depriving it of oxygen. And the reverse was true. So Von Arden got interested in that, wanted to start experiment with oxygen, simply trying to reverse cancer. And along the way, what he discovered is something really powerful about our circulatory system, which is as we age, this thing we now refer to as inflammation happens inside our bodies, this slow, gradual increase in inflammation and that affects every part of our body including our circulatory system. But our circulatory system is actually kind of a weak link. At the very end of your circulatory system is your capillaries and they’re incredibly thin and they’re actually the component where the oxygen and the nutrients gets transferred from the circulatory system to the tissues. So you’ve got these really thin capillaries, thinner than a human hair, actually smaller than a red blood cell. In order for a red blood cell to get in a healthy capillary, it has to fold over like a taco to get in because it can’t fit in normal if it’s fully expanded. So there’s not a lot of room for error. And when you start having this inflammation, it causes blockages in the capillaries. So when that happens, you lose circulation downstream. You have what I call a brownout. All the cells on the other side of that inflammation are no longer getting red blood cells, they’re no longer getting oxygen. Luckily, our body does have a backup generator and that’s called anaerobic respiration. Anaerobic respiration is when they create energy without oxygen. But the problem with it is multi-fold. Number one, it only can produce about 5 % of the energy, it can produce what has oxygen. So immediately the cells are like powering down, they’re not able to do all of their essential functions. problem is it produces a massive amount of metabolic waste and free radicals and those things damage our mitochondria because our mitochondria are incredibly fragile as we spoke about earlier and they’re right at the heart of it wherever you’re producing energy you have some free radicals but now when you shift over to anaerobic all of a sudden you’re just spitting out all sorts of damaging chemicals if you will and it has no energy so it has no way to actually clear it and so it becomes I kind of call it’s like a doom loop, which is it starts with dysfunction the dysfunction causes more free radicals which causes more damage and dysfunction and Soon enough, you know, you’ve got these kind of almost zombie cells. They’re just having a hard time Doing anything and then when you do IWA what’s amazing is the oxygen because it’s Inside the plasma it can get through those blockages. So it immediately starts to feed those downstream cells the oxygen they’ve been starving but more importantly than that immediate fix if you will is they cause an anti-inflammatory effect and this was another like big aha in my healing journeys when I realized There’s plenty of research on this. Anywhere in your body you have inflammation, you have the hypoxia, which is the fancy medical term for oxygen starvation. So inflammation means local oxygen starvation. And anywhere you have oxygen starvation, you have inflammation. They go hand in hand. You can’t have one without the other. And so when we restore oxygen, even in the circulatory system, we can turn off that inflammation that’s happening in our capillaries, reestablish normal blood flow. So you get done doing your EWOT sessions. And Von Arden discovered this. had elderly people, he looked at their capillaries and their throughput, and he had them do just a couple sessions of EWOT, and they came back weeks later, and their microcirculation was still reestablished to more youthful levels. So he was able to open them back up where red blood cells were able to deliver oxygen. really at the root of it all is, you know, every chronic illness you can think of, it has inflammation. Right? mean, there’s not one Alzheimer’s, cancer, autoimmunity, the list goes on and on, name one and it has chronic inflammation. And there’s actually, there’s a gentleman, Arthur Guyton, he wrote the textbook, Medical Physiology, and every doctor any of us has ever gone to had to use that medical physiology book. when they went to medical school, it’s been the standard across the world for over 50 years. And he has this great quote where he says all disease at its root is lack of oxygen. And it’s really true because once the mitochondria break down and we start having inflammation, all the negative effects come from downstream from that. And so that was kind of my. Aha. Light bulb moment, which is if I can turn my mitochondria on it, and I can turn down the inflammation and eventually turn off the inflammation. then like my body will have energy to get ahead. can start to repair itself. It can start to detoxify the immune system. Then we’ll have energy to do everything it needs to do and help, you know, kind of kick on and start to fight a good battle, so to speak. Cheryl McColgan (26:58)Yeah, I mean, I want to go back to how this actually helped you and how you actually found one and all that stuff. But my brain is just going, the one thing that I keep coming to hearing your explanation, and that was an amazing explanation, by the way, for lay people, I can tell you’re an engineer or so. The system where you’re talking about going all the way to the capillaries, I heart disease is the number one killer, right? And we have, I think a lot of it is the chronic inflammation that you’re talking about, but. Obviously once that process is already done, you’re describing how the capillaries can’t get any red blood cells. So to me, it would make perfect sense that this might be not only did it help you in your disease process with Lyme disease and the arthritis and everything, but it seems like it would be pretty amazing for cardiovascular patients or people that don’t have good blood flow, like that on top of the mitochondrial benefit. Brad Pitzele (27:41)Hmm It’s actually, we are helping folks with everything from autoimmunity, cancer, Lyme, long COVID, chronic fatigue, Parkinson’s, heart disease, so many things, because if you can turn off the inflammation and you can give the body energy to heal, it will do just amazing things. That was kind of like the shocking thing to me when I first got into it. was like, wait a second. Like every time I was treating myself as a pin cushion and trying something new, I always had to the question like, what if this doesn’t work? and like what damage could I be doing? know, because there were things that were a little bit risky to be quite honest, where I found out risks, you know, a little bit too late for my liking. But this was one where was like, it’s oxygen. And like, so it was kind of shocking when I started looking at the benefits and I was like, this is kind of crazy that we’re talking about something as simple as oxygen with all these health benefits. But yeah, we’ve had folks with all sorts of different chronic cardiovascular conditions Cheryl McColgan (28:31)Right. Brad Pitzele (28:48)Now, there’s a lot of health benefits to it, but the other crazy thing about oxygen is there’s all these athletic performance benefits. And this is important because directly to your cardiovascular component, which is actually a lot of Olympic teams have used EWAT to improve their athletic performance. because athletic teams are very science driven, there’s some really good research on it showing it improves VO2 max, reduces recovery time. improves short-term memory, it improves power output, et cetera. And all of this is really due to being able to fuel our cells and our muscles more, and also helping clear out all that metabolic waste, because that metabolic waste primarily develops when you have a shortage of oxygen when you’re exercising. Cheryl McColgan (29:34)Amazing that something so simple could be so hugely beneficial. So once you finally saw this, you’re like, Werber knew this about cancer and this guy’s onto this exercise with oxygen thing. Like, well, how do you do it? Where do you get it? Like nobody’s ever seen this before. I think like you’re saying the athletic teams might have it and stuff, but I mean, I’ve certainly never been anywhere where I’ve seen like, hey, get EWOT therapy here. So how did you find it? Brad Pitzele (29:56)Yeah, it’s really, really kind of a rare thing. 15 years ago, it was incredibly rare. There really wasn’t anywhere to go. You could find it occasionally. You might find it in a chiropractor’s office here or there or some sort of recovery clinic. Nowadays, they’re more widespread. So there are places that do it, doctors, chiropractors. But for me, there were a couple of folks selling it, but they were… I didn’t have a whole lot of faith. There was no customer reviews. was no customers talking about it on chat. It was just them as the company and they, a lot of them spoke in superlatives and like marketing speak that it just didn’t make me feel really comfortable. And they were very expensive too. you know, they were maybe the cheapest was 5,000 and the most expensive one I saw was 25,000. and it was this kind of cross hatch of I didn’t have confidence and geez, that’s a lot of money for this next experiment when the last Cheryl McColgan (30:31)yeah. Brad Pitzele (30:49)26 behind me didn’t do anything or 57 or whatever it was. So that’s when I kind of decided, did a little bit more research and decided I was going to try to build my own. Cheryl McColgan (31:00)Yeah, was thinking that I was like, I was an engineer, the next thing would be like, can I just build this? So that’s what you did, obviously, right? Brad Pitzele (31:06)I did it out of necessity because I just didn’t have faith. I built my own. didn’t think it was, I’ll be honest, I didn’t think this was gonna be my solution. Nothing else was. And I started doing it and… You know, slowly but surely I started to walk out of that basement, that proverbial basement. I just kept taking steps up and up. At first it was subtle and then it was kind of all at once sort of thing where I was shocked. You know, was like things like, my gosh, my brain fog’s gone. I’m like focusing in a meeting or I just got down on the floor and played with the kids and I don’t need to lay in bed for two days in pain. And you know, slowly but surely I just felt better and better. And it wasn’t until I saw that same doctor again, and he was like, wow, you’re like a year later. And he was like, wow, you’re so much better. What did you do? And I told him, and he’s like, wow, would you consider selling them to my patients? And that was kind of the, you know, jumping off point where I was like, well, gosh, yeah, maybe we could help other people with this. Cheryl McColgan (32:04)Yeah, that’s awesome. I’m so glad, you know, it’s, it’s, it’s always an interesting thing on podcasts because sometimes you get, I think not on this particular podcast, but other ones, it’s like people that kind of are just selling stuff, you know, or snake oil things or whatever. But what I really love is when there are people that, you know, had their own health problem, they dive into the research, they try it all there, use themselves as an experiment as a pin cushion, as you said, and then they find something that actually works. And then they they make it so that they can share it with everybody else. don’t just keep it to yourself, because I’m sure it kind of felt like a miracle at the time if something finally worked for you. Brad Pitzele (32:41)You know, it really was. I was, because the hardest part is also when you’re in these groups and you’re talking to all these other folks and they’re like, oh, try this, nothing worked and then this worked. And you try that thing and it didn’t work. You you try 57 other different things, as I was saying, and you kind of just start losing any hope. You’re like, I don’t think, I think I’m just that case that there’s nothing that’s going to work. But yeah, when you do find it, it’s, yeah, it’s obviously life changing, even having hope and like, I always tell folks like when you’re really sick, it’s not about, you wanna get to 100%, like 100 % is amazing, it’s the dream we all have when we’re sick, but. more important than 100 % is like feeling better this week than last week or this month than last month because at some point when you’re in it, you just lose a lot of hope and it becomes kind of this like the spiral downward that you just don’t believe in anything and it just lowers you spiritually I just say. And having something to know like, hey, Yeah, it still kinda stinks, but like, remember a month ago it was worse, and so like, now you’re like, yeah, I can’t wait to see how I’m gonna be two months from now, you know, or where am gonna be by this summer sort of thing? Like, it was, it’s kinda the exact opposite. It’s kinda like this hope spiral, if you will. Cheryl McColgan (33:55)Yeah. Well, it’s kind of that’s something that I think it’s good to point out for people too, is that, you you mentioned there is all this research on this. There’s a lot of good science to back up mitochondrial health, that’s kind of mitochondrial health is kind of a long game. And it’s kind of something that you have to continually do not over, you know, just a few days and you’re going to feel so much better. It’s week after week, month after month, the more that you support your mitochondrial health, the more chance you have of really feeling better. So it’s not just this thing where you can try it for a week and you’re like, that doesn’t work. You have to keep up on it for a while, right? Brad Pitzele (34:24)Yeah. Yeah, you’re absolutely right in general speaking. mean, we have… people come to me and they ask like, how long am I going to have to do this for? I tell them is, I can’t say how long until you get to the top of the mountain, so to speak, but I find that most folks who get to the top of the mountain, they feel so good when they do it, they don’t ever want to stop. And some of those folks never really exercised, they hated it, but now they’re like, it’s like 15 minutes, I do it three or five times a week, and I feel amazing, so why wouldn’t I do it? And we talked about that capillary thinning, Cheryl McColgan (34:52)Mm-hmm. Brad Pitzele (34:58)That’s actually a chronic thing that happens to all of us in Western society. And so this is something that’s anti-aging at that very kind of cellular level. So I recommend it for folks, but. I guess for me when I was really sick, always say one of the hardest parts was the ceremony is this what they call them. Counting pills every night, doing this protocol, doing that protocol. You keep adding, like if there’s 10 more minutes in your day, you add 10 more minutes of some protocol that you’re hoping will make you feel better. And then you get to a point where you realize you’re spending six hours of your day, you know, just all you’re doing is these protocols and it just becomes overwhelming. like, even if I felt better, what’s the purpose of all I’m doing is going from from the sauna to the this and I’m doing this pill and I’m doing that. And that’s kind of the, what I found, one of the things I really loved about EWOD was it was something I could do consistently in my home, 15 minutes a day. And it helps with your mitochondrial health. It helps with detoxification. It helps with energy. So it’s like, multiple, it’s kind of multifaceted in the way it benefits you. relatively short period of time. Cheryl McColgan (36:07)Yeah, and you mentioned, and I want to be respectful of your time. know we’re kind of getting a little bit long here, but one of the other things when in respect to mitochondrial health is red light therapy. And there’s also a ton of great research on that. And so I kind of wasn’t surprised when I went to your website that that’s something that you also got into. I mean, I think that’s when you look at the number and the breadth of research on that, I think it’s pretty undeniable that it is good for people that serves a real purpose, that it does help the mitochondria. So at what point, Brad Pitzele (36:34)Yeah. Cheryl McColgan (36:35)after you found the EWAT, I’m assuming you kind of got on this mitochondrial health thing and then maybe stumbled into that stuff. that how it went or is there something else? Brad Pitzele (36:44)Yeah, I started looking at it early on, probably about six months after I was doing EWOT, four to six months right in there I’d say, I started doing Red Light. So you’re right, there’s like tens of thousands of peer-reviewed research studies out there and what it does. They work really interestingly together. Because we mentioned EWAT, when you do it, you increase the supply of oxygen massively, right? It’s a day of oxygen in 15 minutes. So you’re flooding your body with oxygen. And then if you do red light immediately afterwards, what it does is the way it primarily works is it increases oxygen demand in your mitochondria. So it forces the mitochondria to suck up more oxygen. And when they do that, they produce more energy. So any of the research you read on red light whether skin health collagen growth bone mental, brain health, me, athletic recovery performance, healing in general, it all comes from the same thing, is that it’s just forcing our mitochondria to suck up more oxygen and produce more energy. So if you compare those two, you compare them at the same time, you first drive a massive increase in supply of oxygen, and then you increase the mitochondrial demand for it, and so you get this kind of one-two punch. The interesting thing is why I think we need it in today’s society as well is we’re actually deficient on red and near infrared light. And the reason is, if you look at the sun, the sun is full spectrum. has everything from ultraviolet and the blues through the reds and the near infrareds. So when you go outside and it changes throughout the day, early and late in the day, you get more of those reds and near infrareds. And at high noon, you get more of the blues. unfortunately, or fortunately, however you want to look at it, over time as as ⁓ species, we’ve moved indoors and we started using indoor lighting primarily and we spend more and more time there. And then more recently, we’ve switched from incandescent to LED lighting. Now, LED lighting is very energy efficient and one of ways they make it incredibly energy efficient is they take out all the reds and the near infrareds that we experience as heat because obviously you don’t want your lighting to heat your room. You don’t want it to, everyone sees that as energy. waste and to that extent you’re trying to use it for lighting it can be. However, that puts us in a place where we spend a lot of time bathed in blue lights and not really getting enough of the reds and the other parts of the spectrum. Cheryl McColgan (39:27)Yeah, that’s another interesting rabbit hole for people to go down if they haven’t already is just the, you know, changing out some of the lighting in your home or using specific lighting for certain scenarios, like in your bedroom and towards night as you’re getting ready to go to sleep. But anyway, I just want to clarify one quick point there, because I’m envisioning, that was actually what I was envisioning when you started talking about the synergy between red light and the EWAT. So do you like do your EWAT with the red light panel like in front of you or do you just do it right after? Brad Pitzele (39:53)Yeah. I prefer to do it right after. The challenge with doing it right on you is to get the best benefit from red light. Red light works on something called a biphasic dose response, fancy science term, which just means the benefits over time look like a bell curve. So too little, you won’t get any benefit. There’s kind of like a just right where you get peak benefit. And then if you do more, it starts diminishing in benefit. It doesn’t harm. It’s just a waste of time, right? So you spent five more minutes to get less sort of thing. Cheryl McColgan (40:21)Mm-hmm. Brad Pitzele (40:22)with exercising in red light is one, I like to get as much skin exposure as possible so you’re hitting as many mitochondria as possible. And two is you’re moving. So sometimes you’re close to the light, sometimes you’re further away. And so you’re not really able to kind of measure that dose effectively to get inside that biphasic kind of peak zone. Cheryl McColgan (40:43)Okay, no, that makes a ton of sense. Although I still am going to put this out to you that, maybe you put at least on, you know, the little face mask while you’re exercising. I feel like you can attach it to the oxygen part, you know, and just put a red light around it. Maybe that’s a little too, maybe that’s a little too much. But anyway, well, Brad, this has been so wonderful. And I just appreciate you so much sharing your whole journey and then how you came to find this. Brad Pitzele (40:51)There you go. It makes yours waterproof. That’d be fun. Cheryl McColgan (41:09)If people want to connect with you online or learn more about EWOT and learn more about Red Light, where’s the best place that they can find you and connect with you? Brad Pitzele (41:17)Yeah, go to 1000roads.com slash Cheryl and we have a great offer for your listeners. They can check out. You can also ⁓ go to our YouTube channel. put out weekly videos. 1000roads, HQ is our channel. It’s all spelled out, O-N-E-T-H-O-U-S-A-N-D-R-O-A-D-S.com. Cheryl McColgan (41:25)Awesome. Okay, awesome, and all that will be in the show notes for everyone, so don’t feel like you have to write it down. But Brad, again, thank you so much for coming and sharing your knowledge today, and I really appreciate it. Brad Pitzele (41:46)Thank you so much, Cheryl.
What if the cancer treatments you trust are built on the wrong foundation?Dr. Thomas Seyfried has spent decades building the scientific case that cancer isn't a genetic disease. It's a metabolic one. And that distinction changes everything. He breaks down exactly why cancer cells can't survive without glucose and glutamine, why conventional oncology has largely ignored this, and why managing cancer without toxic side effects isn't just possible. It's already happening.Dr. Seyfried also explains why eating meat won't raise your glutamine levels the way most people fear, how nutritional ketosis can cut chemotherapy doses in half, and why a drug called DON could be a turning point in metabolic cancer care if the FDA ever gets out of the way. If you or someone you love is navigating a cancer diagnosis, this conversation could reshape how you think about treatment options. Don't wait to hear it.Ready to try fasting but don't want to do it alone? Join Dr. Katie's 3-Day Guided Fast, for expert support, daily live calls, and a community to fast alongside: Sign-Up Download the FREE Healing Tools Guide: https://bit.ly/drkatie-giftguideMORE FROM KATIE DEMING M.D.6 Pillars of Healing Cancer Workshop Series - Click Here to EnrollTransform your hydration with the Spring Aqua System: https://springaqua.info/drkatieFollow Dr. Katie Deming on Instagram: https://www.instagram.com/katiedemingmd/Please Support the ShowShare this episode with friends & familyGive a Review on SpotifyGive a Review on Apple PodcastWatch on YoutubeDISCLAIMER: The Born to Heal Podcast is intended for informational purposes only and is not a substitute for seeking professional medical advice, di...
In this episode, Mark Bell and Nsima talk with Professor Thomas Seyfried to discuss his metabolic theory of cancer, why he believes mitochondrial dysfunction is at the root of chronic disease, and how nutrition, exercise, and metabolic health may influence cancer risk and outcomes.Dr. Seyfried breaks down his views on glucose, glutamine, ketosis, fasting, GKI, obesity, processed foods, inflammation, and why he believes the current medical system is missing the bigger picture when it comes to prevention and management.Special perks for our listeners below!
Min mest krävande roll hittills Det säger Amanda Seyfried som har huvudrollen i bioaktuella The testament of Ann Lee Lyssna på alla avsnitt i Sveriges Radios app. I intervjun med Björn Jansson berättar hon om vad som krävdes för rollen som Ann Lee där sång, dans och extas förekommer rikligt. Ann Lee var Shaker-rörelsens ledare i USA på 1700-talet. ”Mamma Mia”-skådespelaren Amanda Seyfried har också tränat mycket på att lära sig Joni Mitchells sånger, och hon skulle gärna spela en singer-song-writer i någon kommande film.I inslaget hör vi också Amanda Seyfried sjunga.
P1 Kultur tar sig an biohelgen! Vi pratar med Julia Thelin som långfilmsdebuterar med Mecenaten och med Hollywoodstjärnan Amanda Seyfried om att spela religiös ledare. Dessutom: Charli XCX intar bioduken och Ryan Gosling ska rädda världen. Lyssna på alla avsnitt i Sveriges Radios app. KONST OCH IDENTITET I JULIA THELINS ”MECENATEN”Möt regissören Julia Thelin som gjort bioaktuella ”Mecenaten” där Carla Sehn spelar en städerska som utger sig för att vara gallerist och tar sig an två unga performancekonstnärer (Maxwell Cunningham och Lucas Lynggaard Tønnesen). AMANDA SEYFRIED OM ATT TA TON SOM SHAKER-RÖRELSENS GRUNDAREP1 Kulturs reporter Björn Jansson har pratat med Hollywoodstjärnan Amanda Seyfried som spelar Shaker-rörelsens grundare, som ansågs vara den kvinnliga Jesus av sina följare, i dramamusikalen ”The Testament of Ann Lee”.POPSTJÄRNAN CHARLI XCX GÖR MOCKUMENTÄR OM SITT GENOMBROTT MED BRATSOMMAREN Tina Mehrafzoon från P3 har sett mockumentären ”The Moment” om och med popstjärnan Charli XCX, där Alexander Skarsgård spelar en nyckelroll. RYAN GOSLING SKA RÄDDA JORDEN I ”PROJECT HAIL MARY” – HUR BRA ÄR SCI FI-STORFILMEN?NO-läraren Ryland Grace (Ryan Gosling) vaknar på ett rymdskepp, ljusår från jorden, och inser att han måste stoppa en mystisk substans som hotar att släcka solen. Och därute i rymden lär han känna en stenig utomjordning. Vi frågar vår kritiker Lisa Bergström – är det en barnfilm?INFÖR LYRIKPRISET – LEILA INANNA SULTAN ÄR NOMINERAD FÖR ”STRAFFKOLONIEN”1958 instiftades Sveriges Radios Lyrikpris, som är Sveriges äldsta lyrikpris. Det första gick till författaren Nelly Sachs och förra året tilldelades Nils-Åke Hasselmark priset för diktsamlingen ”Ingenmans strand”. På torsdag är det dags att avslöja vilken svensk poet som får ta emot årets pris. Inför tillkännagivandet sänder P1 Kultur dikter ur de fem nominerade diktsamlingarna som juryn valt ut ur 2025 års utgivning. Vi har idag kommit fram till Straffkolonien av Leila Inanna Sultan. KULTURVECKAN SOM GÅTT – VAD TAR VI MED OSS IN I HELGEN?Roger Wilson blickar tillbaka på kulturveckan tillsammans med programledarkollegan Lisa Bergström och P3:s Tina Mehrafzoon.Programledare: Roger WilsonProducent: Henrik Arvidsson
Hello healers, In this episode of The Moss Report, I travel to Budapest, Hungary, to visit Semmelweis University and sit down with research scientist Dr. Christos Chinopoulos, a leading biochemist whose work has helped advance the mitochondrial and metabolic theory of cancer. Previously on The Moss Report, my father and I spoke with Professor Thomas N. Seyfried of Boston College, who repeatedly pointed to Dr. Chinopoulos as an important scientific collaborator in clarifying key aspects of this theory. In particular, their work has focused on how cancer cells generate energy, the role of mitochondria, the importance of glucose and glutamine, and the idea that a specific metabolic vulnerability may represent an "Achilles heel" of cancer. In this conversation, Dr. Chinopoulos discusses: • his work with Professor Seyfried • how metabolic theory builds on and corrects aspects of Otto Warburg's original framework • why ketogenic therapy may help cancer patients • the limits of targeting glucose alone • glutamine, substrate-level phosphorylation, and cancer cell survival • his laboratory's work on drug development aimed at exploiting metabolic differences between healthy cells and cancer cells • how this research may eventually contribute to more effective and less toxic cancer treatment The episode also includes a brief tour of Dr. Chinopoulos' lab at Semmelweis University, where his team studies tumor metabolism, drug response, and precision approaches to cancer biology. Read the full article, with transcript: https://www.themossreport.com/cancers-metabolic-achilles-heel/ Watch our earlier interview with Professor Thomas N. Seyfried here: https://youtu.be/jiZKpvJ1V20?si=bjAxaV5wkhnLAPKk Subscribe to The Moss Report here: https://themossreport.com/subscribe Your subscription not only gives you access to all our content, but also helps support the longest-running independent voice reporting on less-toxic, more natural approaches to cancer care. Subscribing is a like supporting us on Patreon. Visit our sponsors: Center for Integrative Oncology https://intonc.org Mycolife.US - Mushroom Extracts https://mycolife.us Sign up for the free Essentials of Cancer at The Moss Report website: https://themossreport.com/the-essentials How are you healing today? - Ben Moss
She's played the blushing bride in "Mamma Mia!" and the sidekick to the high-school bully in "Mean Girls". Now Amanda Seyfried takes on the role of Ann Lee, the 18th-century religious leader who founded the Shaker movement in the United States. Eve Jackson hears from Seyfried about the role at the Paris premiere of The Testament of Ann Lee. We also check in with ambassadors of Tuareg culture, Tinariwen, as they return with their 10th album and embark on a European tour. And, we hear from the team behind a powerful new animation telling the story of a child soldier travelling through Guinea, Sierra Leone and Liberia in "Allah Is Not Obliged".
Tell me if this makes sense… We live in a world today characterized by a fetishized pornographic addiction to rape. If it were not so, Law & Order: SVU wouldn’t have made it past a single season – let alone, into SYNdication for nearly 30 years…! I loathe Adorno and the CULTural Marxists who SYNthesized (read: weaponized) Marx and Freud to the general detriment of mankind, beginning with the ‘West’. But, he raised some legit points, as often the baddies do. It’s their SOLUTIONS we all need be wary of. For nigh on 100 years, we’ve basked in the jaundiced glow of the Frankfurt School, as legions of university students continue having their minds and spirits poisoned in the name of ‘Progress’. See also the ancient Roman Collegium, a concept dating back to (at least) the days of Plato – who, incidentally, literally wrote the book on The Republic. I digress… In Adorno’s “Fetish-character” essay, he states, a fetish is a substitute object of desire.[1] I would submit that in the latent undercurrent of this Nietzschean ‘power-evolving universe’ of today’s America; men and women, by and large, secretly harbor a craven desire for rape. It sounds crazy! Until one considers the popularity of Law & Order: SVU for the last 27 years. America is Kung-Fu LARPing, with each new iteration of the ‘fetish substitute object of desire’ further blurring the lines between fantasy and reality (schizoaffective disorder) as we creep ever closer to the Chaos Magick of bringing these secret desires to life. But, beware; LARPing has consequences.[2] The Epstein Saga has been publicly ongoing for 2+ decades. More than a thousand witnesses have come forward – including dozens who’ve accused Trump (E. Jean Carroll) – and yet, only Epstein and Maxwell have been ‘brought to justice’. Speaking of ‘justice’, Thomas Massie probably said it best:[3] Congress created the Department of Justice, Congress funds the Department of Justice, and Congress is responsible for the oversight of the Department of Justice. When will we see justice? I’ll tell you what I’ve not seen. I’ve not seen any arrests from the revelations in the Epstein Files – over 3 million documents describing horrible things, describing unspeakable things, much of it redacted. Over two dozen people have resigned; CEOS, members of government, worldwide. But, I haven’t seen any arrests or investigations here in the United States, from this Department of Justice. Prince Andrew, Duke of York, who has since been stripped of his royalty, his royal titles, due to his affiliation with Jeffrey Epstein, has been arrested. Peter Mandelson, who previously served as UK’s Ambassador to the United States, resigned in disgrace from United Kingdom’s House of Lords and the Labor Party, and he’s been arrested. Former Prime Minister of Norway Thorbjorn Jagland has been charged. But, we don’t see any charges, arrests, or investigations in the United States. What do we see? We see our FBI Director celebrating in the locker room at the Olympics overseas. It’s fine to be proud of this country. But, we should be proud of this country because we have a system of justice that works. And yet we do not. … We need justice. We want the Department of Justice to get to work, and that’s what they need to do – now. The Trump (45/47) DOJ is unwilling to rat itself out – and so are the other 77+ million co-conspirators… And then there’s the 77 million co-conspirators who voted for Epstein’s best friend Trump as many as three times, knowing he’d been accused of sexual assault by dozens of women, and even after he was found liable for sexually assaulting E. Jean Carroll. For 77 million men and women it was not a dealbreaker! He rapes, but he saves. He saves more than he rapes … but he probably does rape.[4] Considering the aforementioned, what would be crazy is not acknowledging America’s fetishized pornographic addiction to rape – which is precisely what we’re doing. We are gaslighting ourselves at this point, as we turn a blind eye to our own culpability. After all – on the eve of America’s 250th Anniversary of Independence – wasn’t this always to be a government of, by, and for The People…? 18 For the wrath of God is revealed from heaven against all ungodliness and unrighteousness of men, who hold the truth in unrighteousness; …21 Because that, when they knew God, they glorified [him] not as God, neither were thankful; but became vain in their imaginations, and their foolish heart was darkened.22 Professing themselves to be wise, they became fools, …24 Wherefore God also gave them up to uncleanness through the lusts of their own hearts, to dishonour their own bodies between themselves: …26 For this cause God gave them up unto vile affections: for even their women did change the natural use into that which is against nature:27 And likewise also the men, leaving the natural use of the woman, burned in their lust one toward another; men with men working that which is unseemly, and receiving in themselves that recompence of their error which was meet.28 And even as they did not like to retain God in [their] knowledge, God gave them over to a reprobate mind, to do those things which are not convenient;29 Being filled with all unrighteousness, fornication, wickedness, covetousness, maliciousness; full of envy, murder, debate, deceit, malignity; whisperers,30 Backbiters, haters of God, despiteful, proud, boasters, inventors of evil things, disobedient to parents,31 Without understanding, covenantbreakers, without natural affection, implacable, unmerciful:32 Who knowing the judgment of God, that they which commit such things are worthy of death, not only do the same, but have pleasure in them that do them. — Romans 1:18, 21–22, 24, 26–32 KJV 4 Rejoice in the Lord alway: [and] again I say, Rejoice.5 Let your moderation be known unto all men. The Lord [is] at hand.6 Be careful for nothing; but in every thing by prayer and supplication with thanksgiving let your requests be made known unto God.7 And the peace of God, which passeth all understanding, shall keep your hearts and minds through Christ Jesus. 8 Finally, brethren, whatsoever things are true, whatsoever things [are] honest, whatsoever things [are] just, whatsoever things [are] pure, whatsoever things [are] lovely, whatsoever things [are] of good report; if [there be] any virtue, and if [there be] any praise, think on these things. — Philippians 4:4–8 KJV #Links Clips [1:58] Etymology (the origins of words) was taken out of schools in the early 1900’s for a reason. (See also entry below) [5:39] Demons in the Headlines EXPOSED: The War for Power and Souls in D.C. | Strange Encounters | Ep 29 – YouTube (See also Blaze Media article below) [3:15] Rep. Massie Asks, “When Will We See Justice” Following Latest Epstein Files Revelations (See also C-SPAN Congressional Chronicle entry below[3:1]) Previous RWR broadcasts referenced 2026-02-25 2026-02-26 Proof of America’s fetishized pornographic addiction to rape Amanda Seyfried Wore A “Prosthetic [redacted]” For ‘Testament Of Ann Lee’ Amanda Seyfried will go to extreme lengths for a film role — especially when it comes to feeling comfortable during a nude scene. The actor wore what she described as a “prosthetic [redacted]” in her recent movie The Testament of Ann Lee, as she revealed in a Feb. 25 interview with BBC’s The Scott Mills Breakfast Show. “This movie, it needed to be graphic, so, like, I had a prosthetic [redacted],” she said in a clip posted to Instagram, which understandably perplexed Mills himself. When pressed for more details, she surprisingly had a rave review about the experience. “It was cool. It was exciting.” Seyfried plays the real-life Ann Lee, a Christian woman in 18th-century Great Britain who viewed herself as a representative of God and eventually founded a religious sect called Shakers, with the film capturing her group’s move across the pond to New York during the Colonial era. Son of megachurch pastor sentenced after horrific materials found at home ‘among worst investigators have seen’ An Indiana megachurch once known for preaching purity and sexual morality has found itself at the center of a scandal that has shaken a congregation, rattled political allies, and ended with a six-year prison sentence. Jonathan Peternel, 24, of Pendleton, was sentenced Friday after pleading guilty in January to one Level 4 felony count of child exploitation and three felony counts of possession of child sexual abuse material. The case drew intense public scrutiny not only because of the disturbing evidence uncovered by investigators, but because his father, Nathan Peternel, remains listed as lead pastor at Life Church and is a longtime mentor and close associate of Indiana Lt. Gov. Micah Beckwith. Why Viewers Say You Should Watch ‘Nymphomaniac’ Alone Due to Its Graphic Scenes Both volumes of Lars von Trier’s Nymphomaniac are streaming on Netflix in the U.S., and its return to an easy, familiar platform has revived a warning that has followed the film since 2013: ‘Watch this one by yourself.‘ … So why does this movie come with a warning like that? The movie’s name actually answers that on its own. The term nymphomania is used to classify someone who has an uncontrollable compulsion toward sex, and that is exactly what the film follows across 2 volumes and 8 chapters. It opens with a woman named Joe, found beaten in an alley. A man named Seligman brings her home, and she begins telling him the story of her life from her earliest sexual memories through decades of escalating need. Von Trier was telling the story of a woman whose entire life is shaped by a compulsion she cannot control. … The discomfort the audience feels isn’t incidental. It’s the mechanism. Von Trier built the film so that watching it puts you closer to Joe’s experience than any non-explicit version ever could. The surface reading is addiction… What Joe is actually chasing is not sex but connection. Every encounter she describes to Seligman moves her further from other people rather than closer to them. Sex becomes the thing she reaches for because the thing she actually needs keeps slipping out of range. That distance between the act and the need behind it is where von Trier plants the real story. The compulsion is real, but the loneliness underneath it is what he keeps circling back to. He called this technique “Digressionism,” a term he coined to describe a storytelling style that deliberately wanders away from its own plot. He cited Marcel Proust as an influence. Nymphomaniac is the final film in what von Trier and critics call the Depression Trilogy. Following Antichrist in 2009 and Melancholia in 2011. After years infiltrating child exploitation rings, expert reveals an even DARKER American underworld | Blaze Media Demons in the Headlines EXPOSED: The War for Power and Souls in D.C. | Strange Encounters | Ep 29 – YouTube [31:30–33:26] Back to the politics piece; everybody within politics – even if they disagree with exploitation or whatever – they show partiality. And, I believe it’s, is it second Peter? … It says, ‘where partiality exists, exists every form of deceit and evil’. We can look it up … but I think that’s it. But, where partiality exists, exists all forms of evil. ***[Did he mean this passage?]For where envying and strife [is], there [is] confusion and every evil work. But the wisdom that is from above is first pure, then peaceable, gentle, [and] easy to be intreated, full of mercy and good fruits, without partiality, and without hypocrisy. – James 3:16–17 KJV*** And, what is happening in our political world that I’ve that I’ve seen now is; you have career politicians – even if they claim to be Christians – they sell access. And, it might be access to conservative organizations. But, they sell access – and they’re partial to donors. … they’re unbelievably partial. And, they’re partial to their ‘club’, as opposed to the people they’re elected to represent. And, you have a bureaucracy that’s in place, and you have these elitists that are in place, that think that they can buy – because they have been able to buy your position – buy you, buy access to you, or buy access to somebody else, and ‘own’ – in this case, a US Senator, what I’m running for. But, it’s across the board for everything; Congressmen, even the President … Everything’s for sale. And, it’s ‘access’ that they’re selling, right? And, that’s the thing that stood out to me the most; partiality. More proof / Trump-Epstein Saga DOJ’s Epstein Files Screwups Get Worse With Unredacted Nudes and Images of Kids The Justice Department is under fire after newly released Jeffrey Epstein case materials reportedly included unredacted nude images and photos involving minors. Analysis by CNN uncovered nearly 100 explicit pictures of two naked young women on a beach, the news outlet reported. The materials also included photos showing a young girl kissing Epstein on the cheek. At least one unredacted image depicted Epstein alongside a nude female, and additional selfie-style nude photos of at least two other unidentified females were also published, with their ages unclear, according to CNN. Under the Epstein Files Transparency Act, which Congress passed and President Trump signed in late November, the DOJ is obligated to omit sexually explicit imagery and anything that might identify victims. The images have now been redacted. DOJ Gives Shameless Reason for Hiding Photo of Howard Lutnick and Jeffrey Epstein Donald Trump’s White House Chief of Staff Susie Wiles is ‘Shocked’ the FBI Dared to Come for Her ‘Uncle Jeff’ shifts focus on Erika Kirk grooming allegations post-Epstein file release – We Got This Covered Most Americans in new survey dispute Donald Trump’s economic boom claim CBS’s new hire appeared 1,700 times in Epstein’s files, and John Oliver just exposed his disturbing emails – We Got This Covered Epstein Had Close Ties to Prosecutor Behind Key Provision of Plea Deal | The New Republic Turns out ICE is just a bunch of scared widdle guys Fear as senator discovers staggering true amount Trump spent on arming ICE – Raw Story Congressional Chronicle – Members of Congress, Hearings and More | C-SPAN.org[3:2] [standalone clip] Rep. Massie Asks, "When Will We See Justice" Following Latest Epstein Files Revelations | Video | C-SPAN.org The Purpose Of the System Is What It Does (POSIWID) Millions at Risk as Android Mental Health Apps Expose Sensitive Data US defense secrets sold to Russians for millions in crypto – Newsweek Tucker Carlson pushes DNA tests for Jews, ‘Khazar’ theory | The Jerusalem Post The largely discredited theory states that Ashkenazi Jews are genetically descended from a Turkic minority that converted to Judaism in the Middle Ages rather than from the 12 tribes of Israel. During Tucker Carlson’s interview last week with Mike Huckabee, the US ambassador to Israel, both men made considerable waves with their takes on history and theology. Anthropic says it will not accede to Pentagon demands as deadline looms | AP News Anthropic said it sought narrow assurances from the Pentagon that Claude won’t be used for mass surveillance of Americans or in fully autonomous weapons. But after months of private talks exploded into public debate, it said in a Thursday statement that new contract language “framed as compromise was paired with legalese that would allow those safeguards to be disregarded at will.” From the Wayback. Why – and why now – is Daily Mail breaking these stories out of the dust bin…? Secret mind-control techniques using TVs revealed in disturbing patent | Daily Mail Online Declassified CIA memo reveals plan to turn citizens into unwitting assassins | Daily Mail Online On the lighter / brighter side… Why age is an advantage for starting a business – Fast Company Sardonic levity, as Rome burns… Images That Might Indicate Society is in Decline | eBaum’s World Caller Dialogue David – WI Feminism dating back to early 1800s (CH: Owenism – Wikipedia) Valerie Solanas, SCUM Manifesto – Wikipedia Friedrich Nietzsche, Beyond Good and Evil (1886)[5] Insanity in individuals is something rare–but in groups, parties, nations, and epochs it is the rule. Bitchute: Etymology (the origins of words) was taken out of schools in the early 1900’s for a reason. Also on YouTube: Etymology ~ The Origins Of Words Was Taken Out Of Schools In The Early 1900s For A Reason – YouTube James – Vancouver The Scribner-Bantam English dictionary : Williams, Edwin B. (Edwin Bucher), 1891-1975 : Free Download, Borrow, and Streaming : Internet Archive #Footnotes Clowney, David W. “On the Fetish-Character in Music and the Regression of Listening” Reading Notes for the 1938 Essay by Theodor Adorno. 3 Nov. 2005, p. 6, users.rowan.edu/~clowney/aesthetics/ReadingGuides/Adorno.ppt. Accessed 26 Feb. 2026. More (e.g., “course guides” at Clowney’s aesthetics page: users.rowan.edu/~clowney/aesthetics/. ︎ Berenson, Alex. “On the Dangers of Cosplay.” Substack.com, Unreported Truths, 11 Jan. 2026, alexberenson.substack.com/p/on-the-dangers-of-cosplay. Accessed 26 Feb. 2026. ︎ C-SPAN. “Congressional Chronicle – Members of Congress, Hearings and More.” C-SPAN.org, C-SPAN, 24 Feb. 2026, www.c-span.org/congress/?chamber=house&date=2026-02-24. Accessed 26 Feb. 2026. Click on “Speakers” tab, select Thomas Massie in “Speakers” dropdown menu, and see timestamp (10:45:03 AM) and transcript of Massie’s remarks. ︎ ︎ ︎ [Massie:] Congress created the Department of Justice, Congress funds the Department of Justice, and Congress is responsible for the oversight of the Department of Justice. When will we see justice? I’ll tell you what I’ve not seen. I’ve not seen any arrests from the revelations in the Epstein Files – over 3 million documents describing horrible things, describing unspeakable things – much of it redacted. Over two dozen people have resigned; CEOs, members of government, worldwide. But, I haven’t seen any arrests or investigations here in the United States, from this Department of Justice. Prince Andrew, Duke of York, who has since been stripped of his royalty, his royal titles, due to his affiliation with Jeffrey Epstein, has been arrested. Peter Mandelson, Who previously served as UK’s Ambassador to the United States, resigned in disgrace from United Kingdom’S House of Lords and the Labor Party, and he’s been arrested. Former Prime Minister of Norway, Thorbjorn Jagland has been charged. But, we don’t see any charges, arrests, or investigations in the United States. What do we see? We see our FBI Director celebrating in the locker room at the Olympics overseas. It’s fine to be proud of this country. But, we should be proud of this country because we have a system of justice that works. And yet we do not. Who are the men that should be investigated? I’ll name them right here. Leon Black; you don’t even have to see past the redactions to see that this man needs to be investigated. Jess Staley; accused of terrible things, it’s right there in the files. Why is he not being investigated? And, Leslie Wexner; why did the FBI list him as a co-conspirator in their own documents in a child sex trafficking case, and then tell him, according to him, that they had no questions for him? Why is that? Well, the Epstein Files Transparency Act requires the DOJ and the FBI to disclose to us their internal memos and emails about how they made those decisions, whether to prosecute or not prosecute. Yet, they have not delivered those memos. And, we still don’t have the memos and documents and emails from 2008, to explain why Jeffrey Epstein was given such a light sentence in what would have been an open and shut case of child sex trafficking, which allowed him to go back and recommit these terrible crimes, create hundreds of more victims, and ensnare so many other people in his conspiracy. Where are those documents that describe those decisions? We need justice. We want the Department of Justice to get to work, and that’s what they need to do – now! Jones, Marcie. “Gee, Look at All These Co-Conspirators in the Epstein Files That Pam Bondi and Kash Patel Say Never Existed.” Wonkette.com, Wonkette, 25 Feb. 2026, www.wonkette.com/p/gee-look-at-all-these-co-conspirators. Accessed 26 Feb. 2026. ︎ Nietzsche, Friedrich. Beyond Good and Evil. 1886. Gutenberg.org, Chapter IV. Apophthegms And Interludes, ln. 156, 4 Feb. 2013, gutenberg.org/files/4363/4363-h/4363-h.htm. Accessed 28 Feb. 2026. from The Complete Works of Friedrich Nietzsche (1909-1913). ︎
The Testament of Ann Lee is a 2025 epic historical musical drama film directed by Mona Fastvold, who co-wrote it with Brady Corbet. The film stars Amanda Seyfried as Ann Lee, the founding leader of the Shakers religious sect in the 18th century. The supporting cast includes Thomasin McKenzie, Lewis Pullman, Stacy Martin, Tim Blake Nelson, and Christopher Abbott.The Testament of Ann Lee had its premiere in the main competition of the 82nd Venice International Film Festival on 1 September 2025, where it was nominated for the Golden Lion, and was given a limited theatrical release in the United States on 25 December and the United Kingdom on 27 February 2026 by Searchlight Pictures. The film received positive reviews from critics, with Seyfried receiving acclaim for her performance (often described as "career-best") and earning nominations for the Golden Globe Award and the Critics' Choice Award for Best Actress. Hosted on Acast. See acast.com/privacy for more information.
Some exciting news—The Take is now on Patreon: www.patreon.com/kermodeandmayo. Become a Vanguardista or an Ultra Vanguardista to get video episodes of Take Two every week, plus member‑only chat rooms, polls and submissions to influence the show, behind‑the‑scenes photos and videos, the monthly Redactor's Roundup newsletter, and access to a new fortnightly LIVE show—a raucous, unfiltered lunchtime special with the Good Doctors, new features, and live chat so you can heckle, vote, and have your questions read out in real time. Amanda Seyfried is our special guest this week. She's starred in Mean Girls, The Housemaid and Mamma Mia!, but she's never been a Mancunian... until now. She joins Simon alongside writer-director Mona Fastvold to talk about The Testament of Ann Lee, in which Seyfried stars as the titular leader of the Shakers. You might not have heard of her and the 18th century radical religious sect she founded—and we promise you've definitely never seen a musical about her. Seyfried talks about her struggle to crack a Manchester accent for the role, never mind all that ecstatic song and dance—and we hear from Fastvold about he old-school filmmaking techniques that helped her and co-writer husband Brady Corbet bring this unique story to the screen on shoestring budget. Mark will review The Testament of Ann Lee next week, but we've got four more movie reviews for you in the meantime—it's a packed show! First, The Secret Agent, where paranoia and deception collide as an ex-academic gets caught up in South American political turmoil. Then there's If I Had Legs I'd Kick You, a darkly comic tale of maternal burnout pushed to surreal extremes. We also have Wasteman—a gritty prison drama starring Rye Lane's David Jonsson. And finally, Good Luck Have Fun Don't Die, a genre-bending evil-tech adventure starring Sam Rockwell. Plus all the usual delights: the box office top 10, the unpredictable joy of the Laughter Lift, and your tip-top correspondence. Don't miss it. Timecodes 00:00:00 Show starts 00:10:09 The Secret Agent review 00:22:02 Box Office Top 10 00:39:24 Mona Fastvold and Amanda Seyfried interview 01:01:24 If I Had Legs I'd Kick You review 01:07:35 Laughter Lift 01:12:09 Wasteman review 01:19:13 Good Luck, Have Fun, Don't Die review You can contact the show by emailing correspondence@kermodeandmayo.com or you can find us on social media, @KermodeandMayo Please take our survey and help shape the future of our show: https://www.kermodeandmayo.com/survey EXCLUSIVE NordVPN Deal ➼ https://nordvpn.com/take Try it risk-free now with a 30-day money-back guarantee! A Sony Music Entertainment production. Find more great podcasts from Sony Music Entertainment at sonymusic.com/podcasts and follow us @sonypodcasts To advertise on this show contact: podcastadsales@sonymusic.com Learn more about your ad choices. Visit podcastchoices.com/adchoices
Fresh off a flight from LA, Vogue's cover star, Amanda Seyfried is back in New York and on The Run Through to talk about award season!“I will say my favorite part … was being at the A24 party at the Chateau,” says Seyfried reflecting on the Golden Globes that happened Sunday evening. “I was just on the couch with a bunch of people that I like and don't ever see except at award shows.” Seyfried says she was surprised when a conversation in the Golden Globes ballroom with Jennifer Lawrence was picked up by cameras. “There are still moments when I forget that people are watching it,” says Seyfried. “It was a little bit unnerving when I saw that because I just believed, I guess, stupidly that it was a private conversation.” Seyfried was a two-time nominee at the ceremony for her roles in the Testament on Ann Lee and the television series Long Bright River. With award season in full swing, she's been working closely with her stylist Elizabeth Stewart to make sure she is red carpet ready. “We've been wearing a lot of Prada and we decided to wear a Versace [to the Golden Globes], which is always trusted and beautiful and classic as well. Away from Hollywood, Seyfried's wardrobe is much more casual as she cares for 52 animals on her farm upstate. “I'll wear the big tall muck boots,” says Seyfried. “The ones you can't drive a car in 'cause your foot can't reach the pedal.” Her animals include peacocks, chickens, goats, horses, donkeys and a new rescue rabbit named Bugsy that is a bit stand-offish. “He could be 37 years-old.” says Seyfried. “ I have absolutely no idea. He's got a droopy wet eye. But he's very nice it seems.” In The Testament of Ann Lee directed by Mona Fastvold, Seyfried plays the titular character who is credited with creating the Shaker religious community in the mid-18th century. “The Shakers worshiped through song and dance,” says Seyfried on the challenge of undertaking the role as their leader.“The singing had to be second nature.” says Seyfried on her performance. “But with singing, I've always been judging myself as I've been doing it. Even in Les Mis, I wasn't present the way I was. So I had to let go of that very early on. And the key to that was she's human and I need to feel it. It's not about how it sounds. It's about how it feels. And I need the audience to become a Shaker for two and a half hours.”While promoting the film, Seyfried's 8 year-old daughter Nina was introduced to one of her mother's earlier roles in the cult classic Mean Girls. “She said that she didn't think it was that funny,” recalls Seyfried. “but she really loved my role. That was Nina's critique of Mean Girls at age eight.”The Run-Through with Vogue is your go-to podcast where fashion meets culture. Hosted by Chloe Malle, Head of Editorial Content, Vogue U.S.; Chioma Nnadi, Head of British Vogue; and Nicole Phelps, Director of Vogue Runway, each episode features the latest fashion news and exclusive designer and celebrity interviews. Learn about your ad choices: dovetail.prx.org/ad-choices
Podcasting is a privilege as Steve is joined by Dan Kois and Rebecca Onion to unpack and cackle at the domestic thriller schlockfest The Housemaid. Sydney Sweeney and Amanda Seyfried star in the Paul Fieg-directed tale of two women facing off to rule the McMansion roost.Next, Seyfried proves she's got the range as the panel joins the chorus appraising her performance in The Testament of Ann Lee, the epic tone poem and musical biopic about the founder of the Shakers directed by Mona Fastvold. Finally, Julia hops on the call to join a conversation with Alia Hanna Habib, the influential book agent who is divulging hard-won publishing world insights in a new book Take It from Me and in the Substack Delivery & Acceptance.In a Slate Plus bonus episode, the panel addresses a listener questioner from a U.S. history teacher about syllabus-worthy pop culture.EndorsementsDan: The Ruth Asawa retrospective at MoMA which illuminates the work and life of the prolific artist.Rebecca: A bunch of books including Canticle by Janet Rich Edwards, The Ax by Donald E. Westlake, and True Grit by Charles Portis.Steve: The essay "East Side Story" about Marty Supreme by Nawal Arjini in the New York Review of Books.---Email us your thoughts at culturefest@slate.com. Podcast production by Benjamin Frisch. Production assistance by Daniel Hirsch. Hosted on Acast. See acast.com/privacy for more information.
Podcasting is a privilege as Steve is joined by Dan Kois and Rebecca Onion to unpack and cackle at the domestic thriller schlockfest The Housemaid. Sydney Sweeney and Amanda Seyfried star in the Paul Fieg-directed tale of two women facing off to rule the McMansion roost.Next, Seyfried proves she's got the range as the panel joins the chorus appraising her performance in The Testament of Ann Lee, the epic tone poem and musical biopic about the founder of the Shakers directed by Mona Fastvold. Finally, Julia hops on the call to join a conversation with Alia Hanna Habib, the influential book agent who is divulging hard-won publishing world insights in a new book Take It from Me and in the Substack Delivery & Acceptance.In a Slate Plus bonus episode, the panel addresses a listener questioner from a U.S. history teacher about syllabus-worthy pop culture.EndorsementsDan: The Ruth Asawa retrospective at MoMA which illuminates the work and life of the prolific artist.Rebecca: A bunch of books including Canticle by Janet Rich Edwards, The Ax by Donald E. Westlake, and True Grit by Charles Portis.Steve: The essay "East Side Story" about Marty Supreme by Nawal Arjini in the New York Review of Books.---Email us your thoughts at culturefest@slate.com. Podcast production by Benjamin Frisch. Production assistance by Daniel Hirsch. Hosted on Acast. See acast.com/privacy for more information.
The Housemaid is a 2025 American erotic psychological thriller film co-produced and directed by Paul Feig from a screenplay by Rebecca Sonnenshine, based on the 2022 novel of the same name by Freida McFadden. The film stars Sydney Sweeney, Amanda Seyfried, Brandon Sklenar, Michele Morrone, and Elizabeth Perkins. Its plot follows a young woman with a troubled past (Sweeney) who becomes the live-in housekeeper for a wealthy family (Seyfried and Sklenar). Their seemingly perfect life unravels when she discovers their household hides dark secrets.The Housemaid premiered at the Axa Equitable Center in New York City on December 2, 2025, and was released in the United States by Lionsgate on December 19, 2025. The film received positive reviews from critics, who praised Feig's direction and the performances of the cast (particularly Seyfried), as well as the film's plot twists and sense of fun. Hosted on Acast. See acast.com/privacy for more information.
On the December 27, 2025 edition of The Richard Crouse Show we meet firector James House and producer Caroline Sciama of “Elizabeth Taylor: Rebel Superstar,” a compelling three-part docuseries that reexamines Taylor’s life through a modern lens, highlighting her evolution from child star under MGM’s control to a trailblazing activist, businesswoman, and feminist icon. It features exclusive interviews with Taylor’s son Chris Wilding, granddaughter Naomi Wilding, and stars like Sharon Stone, Joan Collins, and Paris Jackson, alongside rare archival audio and can be seen on Hollywood Suite. Then, we meet Atom Egoyan and Amanda Seyfried of the new film “Seven Veils.” In this a new psychological thriller, now playing in theatres, Seyfried is Jeanine, a director dealing with repressed trauma as she mounts a production of her mentor’s most famous work, the opera “Salome.” Rich with metaphor and suspense “Seven Veils” is an intellectual thriller about art imitating life. Finally, we’ll meet Keira Jang, star of “Can I Get A Witness?” a Canadian eco-sci fi/coming-of-age film now on streaming sevices. It’s set in a future where climate change and world poverty have been eradicated. To mitigate these modern-day issues, travel and technology are banned and every citizen must end life at 50. Documenting the process are artists as witnesses, like the character Kiera plays, a teenager on her first day on the job.
On the December 27, 2025 edition of The Richard Crouse Show we meet firector James House and producer Caroline Sciama of “Elizabeth Taylor: Rebel Superstar,” a compelling three-part docuseries that reexamines Taylor's life through a modern lens, highlighting her evolution from child star under MGM's control to a trailblazing activist, businesswoman, and feminist icon. It features exclusive interviews with Taylor's son Chris Wilding, granddaughter Naomi Wilding, and stars like Sharon Stone, Joan Collins, and Paris Jackson, alongside rare archival audio and can be seen on Hollywood Suite. Then, we meet Atom Egoyan and Amanda Seyfried of the new film “Seven Veils.” In this a new psychological thriller, now playing in theatres, Seyfried is Jeanine, a director dealing with repressed trauma as she mounts a production of her mentor's most famous work, the opera “Salome.” Rich with metaphor and suspense “Seven Veils” is an intellectual thriller about art imitating life. Finally, we'll meet Keira Jang, star of “Can I Get A Witness?” a Canadian eco-sci fi/coming-of-age film now on streaming sevices. It's set in a future where climate change and world poverty have been eradicated. To mitigate these modern-day issues, travel and technology are banned and every citizen must end life at 50. Documenting the process are artists as witnesses, like the character Kiera plays, a teenager on her first day on the job.
I've been covering Amanda Seyfried's work consistently since starting my career — particularly starting the best part of my career, focusing on interviews. In fact, one of my very first press days was for Atom Egoyan's Chloe, which Seyfried headlines alongside Julianne Moore. With every press day that followed, I was constantly struck by Seyfried's general warmth and her passion for her work, but especially by her openness while talking about it. About 25 years into her career, I'm still wowed by those same qualities, but a new one surfaced during our latest conversation, our very first Collider Ladies Night interview. It's the importance Seyfried puts on being there for actors on the rise, like her The Housemaid co-star, Sydney Sweeney.The two star in the highly anticipated adaptation of Freida McFadden's incredibly popular novel. Sweeney plays Millie, a young woman who accepts a job working as a housemaid for Seyfried's character, Nina Winchester, and her family. Initially, it seems like a dream gig. The Winchester home is beautiful and Nina appears to be a lovely employer. However, on day one of the job, things take a turn. Or rather, Nina takes a turn.In celebration of The Housemaid's release this weekend, and The Testament of Ann Lee's upcoming rollout, Seyfried joined me for a Collider Ladies Night conversation to discuss the experiences that led her to this moment — a truly exceptional moment during which she has two wildly different films hitting theaters at about the same time, both featuring breathtaking work from her. Hosted on Acast. See acast.com/privacy for more information.
Special Bonus Episode! Mean Book Club is four ladies (UCB, BuzzFeed, College Humor, Impractical Jokers) who read, discuss and whine about NYT bestselling books that have questionable literary merit. It's fun. It's cathartic. It's perfect for your commute. New podcast (almost) every Tuesday! Send any future book suggestions to meanbookclub@gmail.com! Follow us on the socials @meanbookclub! Rate, like, subscribe, and check out our Patreon page at patreon.com/meanbookclub to become a true patron of the mean arts. CREDITS: Hosted by Sarah Burton, Clara Morris, Johnna Scrabis, & Sabrina B. Jordan. This episode was produced and edited by Sarah Burton. Special thanks to FSM Team for our theme song, "Parkour Introvert." You can get it here: https://www.free-stock-music.comBecome a supporter of this podcast: https://www.spreaker.com/podcast/mean-book-club--3199521/support.
"Avatar: Fire & Ash" is the third entry in the phenomenally successful sci-fi franchise, and delivers exactly what you'd expect, 3 hours and 12 minutes of spectacular visuals and zippy action. The story, however, is very repetitive and has little to offer that's new. Plus, there's no real sense of peril. The attraction is the remarkable eye candy, so if you opt to see it, go ahead and splurge on the Imax version. The very busy actresses Sydney Sweeney and Amanda Seyfried star in the goofy psychological thriller "The Housemaid." Sydney plays the maid who uncovers some dark secrets in the household of wealthy Amanda. Seyfried is excellent but Sweeney is merely adequate in this trashy flick. "The Housemaid" doesn't clean up because the filmmakers didn't have the nerve to go full camp...which would have been the better route to take. The strange political thriller "The Secret Agent" is a nominee for this year's Critics' Choice Award for Best Foreign Language Film. Set during Brazil's political strife of 1977, Wagner Moura plays a tech pro who is being pursued by secret foes. The structure of “The Secret Agent” is disjointed for sure, but only that adds to its offbeat appeal. The animated musical “David” is the latest from faith-based distributor Angel Studios. This well made and involving movie tells the story of the King of Israel from his early days as a lowly shepherd to his heroic defeat of Goliath and his ascension as leader of his people. The story's violence has been toned down, but it's still faithful to the Biblical themes and is a painless introduction for the kiddies.
Route 66 will turn 100 next year. It slithers along I-40 as a road that almost didn't think it needed to be there. So much of roadside America vanished once they built the interstate, but you can still see signs of it here and there.While glancing over at Route 66, as I drove back from Ohio to California, I couldn't help but see how America has become so divided between those who exist in the virtual new frontier of the internet and those who still live in the long-forgotten old America, an America Big Tech will soon leave behind. A week or so ago, while driving through Lakewood, Ohio, I saw two police officers helping a ranting and raving woman open her locked car door. They just stood there, with their heads down, doing their job as temperatures sank to 20 degrees and the snow flurries swirled around their heads. They wanted to be home with their families, but there they were, doing their jobs.Cleveland is a symbol of an America in steep decline. Emptied out factories, some areas so crippled by poverty, they look like third-world countries. The businesses have been abandoned, graffiti covers almost every block, and most people know to stay away from these neighborhoods.My daughter was commissioned to paint a mural on the side of an abandoned building near a vacantd lot in a lower-middle-class neighborhood in Cleveland to dress it up a little. It is cities like Cleveland that Trump was elected to help fix. And it is why bringing in millions from poverty-ridden countries only means these Americans are pushed to the back of the line. His methods might be crude and in some cases, reckless, but his intentions have always been the same. Not just to Make America Great Again, but to Make America Safe Again. The Democrats can't keep America safe because they have become disconnected from real life and exist inside a self-perpetuating feedback loop that tells them only what they want to hear.They can't keep us safe on the streets. They can't keep businesses safe. They can't keep us safe on the roads. They can't keep families safe in cities ruled by gang warfare. They can't keep women safe from violent attacks by random lunatics who should not even be roaming the streets at all. They can't keep women and girls safe in locker rooms. They can't keep children safe in classrooms where they insist upon rewriting America's history and foisting an ideological cult upon the young so that they, too, grow up believing they can change their gender if the color of their skin makes them bad people. They can't keep those strung out on fentanyl safe either, the hundreds of thousands of overdoses every year. If anything, the Democrats are fighting to protect the rights of the drug cartels, like they fight to protect the rights of illegal immigrants, and like they fight to protect the rights of criminals. The Democrats exist in a protective bubble. They never see or hear the stories that come in brief flashes: a woman was punched on the subway, a man was carjacked with his toddler watching, a store was robbed, and a family was shot at a fast-food restaurant. Protesters beat someone up for wearing a MAGA hat, and a woman is kicked out of a gym for accurately calling attention to a naked man in the locker room. They can't really address any of these problems, so they shapeshift their message to see what works. Once they win, they can't deliver. Trump is trying to deliver, and all they're doing is trying to stop him. Democrats RisingTyler Robinson has never looked better. He was smiling as he strode into the courthouse on trial for the murder of Charlie Kirk. And why wouldn't he be smiling? He knows he's a hero on the Left, and he knows that a loud faction of the Right is defending him by blaming - wait for it - Israel.Amanda Seyfried has refused to apologize for saying Charlie Kirk was “hateful,” even if her words echoed Robinson's, who said that Charlie deserved to be killed because he “spread too much hate.” Seyfried, who has a major movie coming out in a couple of weeks, will be celebrated for her comments and will likely earn an Oscar nomination for a different role in which she plays the presumed second coming of Christ in the Shaker movement. Oh, the irony. The Kirk assassination should have rocked America to its core, as previous political assassinations have. Maybe it would have shaken us all awake so that we could ask, How did we ever get here? But if the Trump near-assassination didn't do it, if so many of the Real Housewives of the Democratic Party celebrated with cold glasses of Chardonnay and an Instagram post, nothing would.The Democrats have the wind at their backs with major wins in elections all over the country, including the first Democrat to win in Miami in almost 30 years. They believe they have the messaging right and are hitting on affordability, healthcare, and a living wage. So by the looks of it now, nothing can stop them from taking the House in 2026 and the presidency in 2028.They haven't changed a thing. They haven't tacked to the center. They haven't confronted “gender affirming care.” In fact, they're openly bragging about supporting it, at least if the performative meme factory of frontrunner Gavin, the Great White Male Hope for the Democrats in 2028, is any indication.Here is Ben Shapiro.To them, opposing “trans kids” is “hate.” And that is what got Charlie Kirk killed, except that his death was like lifting a fallen tree in the forest. All of the creepy crawlies came out. It isn't just the Left. Some on the Right are making a play for the giant hole Charlie left behind. “I don't care about the midterms,” says Candace Owens. “I hate the Republican Party,” says Tucker Carlson. Marjorie Taylor Greene is enjoying her fifteen minutes of fame by being a useful idiot for the Left, telling CNN and 60 Minutes everything they want to hear. MAGA is tearing itself apart. What separated Charlie Kirk from the parasitic vultures who have flown in to peck at the corpse is that he wasn't in it just for clicks and views or for money. He was in it because he believed in it, and he was dedicated to helping defeat the Left to save this country, especially its youth. Without him, however, the Democrats can use their powerful media machine to manipulate the message, even to deflect from their own craziness long enough to fool the public into trusting them before they once again demand that all must comply or else. That's our potential future if the Right can't get it together to mount a proper offense.The problem for the Democrats is that the mass delusions they push onto the American public have almost no practical application in the real America, the one I've just seen as I've driven across the country.What I saw was an America that needs politicians not just for “affordability,” but to keep things running - buses, grocery stores, schools, and most especially, to keep them and their neighborhoods safe, something the Democrats can't and won't do. Trump telling working-class Americans to buy fewer dolls this Christmas is the kind of thing that can sink a presidency and a legacy. True, he isn't running for re-election, but it's the kind of thing that will stick. The truth matters less than the perception, and for now, the Democrats control the media and thus, the message. To defeat the Democrats, Trump and MAGA will have to find a way to tell Americans to buy as many dolls as they want because now they can afford them. Sticks and StonesThe greatest crime imaginable to the Good People of the Left is a bad word. I was there when we began curating our soft language. Make the words inoffensive, and the problems will be solved. There is no homelessness; there are the “unhoused” people. There are no drug addicts, but mentally ill people. We don't give away our pets, we “rehome” them. It isn't catastrophic, life-altering medications and surgeries that sterilize children and wreck their bodies for life. It's “gender affirming care.” So, of course, Trump would be their biggest enemy. He got famous for saying anything, even if — especially if — it was shocking. The Left knows this and yet, they can't help themselves. It's “dangerous” because bad words are “dangerous” in a Woketopia ruled by soft language.They exist in an ecosystem that turns the story of a Cinnebon employee caught on tape using the N-word into the biggest scandal of the week. That convinces them that every terrible thing they've said and done for ten years has been justified. This country is infested, they believe, with “racists,” and they plan to do something about it once they take back power. How will they do that? By mandating thought and speech, just as they did last time. The internet gives them that kind of control to decide who gets to stay and who has to go. They won't only use it, they'll expand on it. But words are nothing compared to a bullet in the neck, a punch in the face, or a knife across the throat. But even if the victims are not white, crime remains an elusive concept for them because crime presents as “systemically racist police,” or mass incarceration, or something Trump and MAGA did. They especially ignore crimes by illegal immigrants. Cleveland and other cities like it have been ravaged by crime and drugs. Trump's answer was to send in National Guard troops to protect ICE agents and clean up the cities. Then he began bombing the cartel boats bringing drugs to the United States. Everything he does is to keep America safe, and yet, to the Democrats, that's criminal activity. So the citizens languish, overdose, and die, and the only person to ever do anything about it is the guy they still want to impeach, destroy, or even kill. Of Thee I SingI have just spent the past few weeks driving across this big, beautiful, complicated country, and I've never seen a greater disconnect between the traumas foisted upon Americans by the Democrats and the reality of life on the ground. In real life, we can still see each other as fellow Americans. The guy in the elevator can pet my dog and talk to me about how much he misses his dog, who died last year. There are no identifiers that pit us against each other, unless someone is wearing a MAGA hat or a No Kings t-shirt.But that is not true online. We are tracked and traced, our likes and our friends are used to put us in a specific category. An America ruled by the Left will take that one step further, all the way to 1984, where those allowed in are only those who love Big Brother.During the last Civil War, one of the greatest concerns was holding the Union together. It mattered that America survive. Here's hoping we honor their sacrifice, find a better way forward for all of us, and yes, hold onto the dream. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.sashastone.com/subscribe
In this ZFF Masters episode, Amanda Seyfried reflects on the roles and experiences that have shaped her into one of the most beloved and versatile performers of our time. She discusses the impact of iconic films like MAMMA MIA! and MEAN GIRLS and shares behind-the-scenes stories from fan-favourite projects. She also offers insights into her latest film, THE TESTAMENT OF ANN LEE which she presented at the 21st Zurich Film Festival, already marking her as a major contender this awards season. Amanda Seyfried has long been one of the defining faces of contemporary American cinema. After gaining early attention in the TV series AS THE WORLD TURNS and ALL MY CHILDREN, she broke through with the hit comedy MEAN GIRLS (2004), paving the way for major film roles. She went on to star in HBO's BIG LOVE and lead the global phenomenon MAMMA MIA! (2008) and its sequel, showcasing her vocal talent. Her range expanded further through acclaimed performances in JENNIFER'S BODY, CHLOE and LES MISÉRABLES. Seyfried earned her first Academy Award nomination for portraying Marion Davies in David Fincher's MANK (2020). She achieved her biggest television success with her Emmy and Golden Globe winning performance as Elizabeth Holmes in THE DROPOUT (2022). ZFF Masters are in-depth conversations with renowned voices from world cinema, open to the public and held during the Zurich Film Festival. They offer audiences a rare opportunity to gain insight into the creative process and artistic vision of leading figures in film. This episode is presented by Deadline. Cover photo: Anne Morgenstern #ZFF2025 #zurichfilmfestival
Cancer can be seen as a seed that only sprouts in the right soil—the body's inner landscape. Today, that soil is changing fast, and cancer rates are climbing, especially among young people. Our modern diet—packed with sugar, processed foods, and nonstop snacking—keeps the body flooded with signals to grow, not heal. But there's good news: by eating real, colorful foods and giving the body time to rest between meals, we can calm inflammation, balance our gut, and make our inner soil far less welcoming to disease. The power to shift the story lies in every bite and every pause we take. In this episode, I discuss, along with Dr. Jason Fung and Dr. Thomas Seyfried, how modern diets and constant eating create a fertile soil for disease. Dr. Jason Fung is a physician, author, and researcher. His groundbreaking science-based books about diabetes and obesity, The Diabetes Code, The Obesity Code, and The Complete Guide to Fasting have sold over one million copies and challenged the conventional wisdom that diabetics should be treated with insulin. Dr. Fung is also the co-founder of The Fasting Method, a program to help people lose weight and reverse Type 2 Diabetes naturally with fasting. His work on fasting has been cited by CNN, Time, The Atlantic, Forbes, The Toronto Star, and many other media outlets. His latest book is The Cancer Code: A Revolutionary New Understanding of a Medical Mystery. Dr. Thomas Seyfried is an American professor of biology, genetics, and biochemistry at Boston College. He received his Ph.D. from the University of Illinois Urbana-Champaign in 1976 and did his postdoctoral fellowship at the Yale University School of Medicine. Dr. Seyfried has over 150 peer-reviewed publications, and his research focuses primarily on the mechanisms driving cancer, epilepsy, and neurodegenerative diseases and calorie-restricted ketogenic diets in their prevention and treatment. He is the author of Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer and presently serves on the Nutrition & Metabolism, Neurochemical Research, Journal of Lipid Research, and ASN Neuro editorial boards. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN to save 15%. Full-length episodes can be found here:Is Cancer Caused By Sugar? How Can My Diet Help Prevent Cancer? A Radical New Dietary Approach To Cancer Treatment
What if the cancer treatment that works best is the one pharmaceutical companies can't profit from? What if one of the cancer treatments that works best is the one the pharmaceutical companies can't profit from?!Dr. Katie sits down again with Professor Thomas Seyfried to explore why the medical system resists alternative approaches to a disease that claims over 1,700 lives daily in the U.S., and what's actually driving cancer at the cellular level. They reveal a specific therapeutic strategy that targets both fuels cancer cells depend on to survive.Dr. Seyfried explains how cancer isn't the genetic lottery you've been led to believe, it's a metabolic condition with a metabolic solution. You'll learn why your body's normal cells thrive on completely different fuel than cancer cells do, and how a compound called DON (a glutamine antagonist) combined with therapeutic ketosis creates conditions where healthy cells flourish while cancer cells can't survive. Chapters:00:13:25 – Starving the Tumor00:16:22 – The Banned Cancer Drug00:21:03 – Beyond the Keto Diet00:32:00 – Why Healing Threatens the ‘System'00:37:15 – The Genetic MythDr. Katie and Dr. Seyfried discuss the practical challenges patients face when trying to find providers who understand this science, why measuring your glucose-ketone index matters more than following any specific meal plan.Dr. Seyfried's research team is seeing remarkable outcomes in advanced cases that conventional medicine has given up on, and he shares exactly what that approach looks like.Listen and learn why the paradigm shift in cancer management isn't just coming, it's already here, waiting for the rest of the world to catch up.Dr. Seyfried: https://www.bc.edu/bc-web/schools/morrissey/departments/biology/people/faculty-directory/thomas-seyfried.htmlAccess the FREE Water Fasting Masterclass Now: https://www.katiedeming.com/the-healing-power-of-fasting/ Transform your hydration with the system that delivers filtered, mineralized, and structured water all in one. Spring Aqua System: https://springaqua.info/drkatieMORE FROM KATIE DEMING M.D. Work with Dr. Katie: www.katiedeming.com 6 Pillars of Healing Cancer Workshop Series - Click Here to Enroll Follow Dr. Katie Deming on Instagram: https://www.instagram.com/katiedemingmd/ Email: INFO@KATIEDEMING.COM Please Support the Show Share this episode with a friend or family member Give a Review on Spotify Give a Review on Apple Podcast Watch on Youtube: https://youtube.com/playlist?list=PL5LplU70TE9i01tW_7Tozi8b6X6rGBKA2&si=ZXLy5PjM7daD6AV5 DISCLAIMER: The Born to Heal Podcast is intended for informational purposes only and is not a substitute for seeking professional medical advice, diagnosis, or treatment. Individual medical histories are unique; therefore, this episode should not be used to diagnose, treat, cure, or prevent any disease without consulting your healthcare provider.
Welcome to The Superhumanize Podcast. I'm your host, Ariane Sommer, and today we're diving into one of the most paradigm-shifting conversations in modern medicine: the metabolic theory of cancer.For decades, we've been told that cancer is primarily a genetic disease, a matter of unlucky mutations that require aggressive pharmaceutical interventions. But what if that's only part of the story? What if cancer is fundamentally a metabolic disease, a disorder of cellular energy production that we can address through diet, lifestyle, and targeted metabolic therapies?This isn't fringe science. And it's giving patients new hope, and new options, beyond the standard cut, poison, and burn model. Today, I'm thrilled to welcome Dr. Donese Worden to the show. Dr. Worden is a board-certified Naturopathic Medical Doctor, researcher, and global health educator who has dedicated her career to bridging conventional and alternative cancer care. She's collaborated with Banner MD Anderson Cancer Center, served as CEO of Care Oncology, and works directly with Dr. Seyfried on metabolic cancer research. She's also the creator of the 7 Pillars of Health framework, a comprehensive approach to resilience that addresses everything from sleep and gut health to spiritual wellbeing.Dr. Worden's motto is 'Educate, Empower, Enlighten,' and that's exactly what we're going to do today. We'll explore the metabolic theory of cancer, discuss both prevention and treatment strategies, and give you a roadmap for building resilience at every level.Episode Highlights00:00 Welcome + why the “metabolic theory of cancer” matters02:00 Genetics vs. metabolism: why only ~5% is strictly genetic (and gene expression is modifiable)03:45 Warburg's mitochondrial lens; PET scans lighting up because cancer voraciously consumes sugar06:45 How we veered away historically; incentives that kept oncology gene-centric09:00 What damages mitochondria today: toxins, antibiotics (without mitigation), chronic stress10:30 Stress as a metabolic driver; why it keeps glucose high even on a “good” diet12:30 Ketogenic therapy for cancer: high fat, lower protein (individualized), carbs mainly from veggies15:00 Measuring correctly: Keto-Mojo, GKI (Glucose-Ketone Index); skip urine strips for accuracy17:00 Fast stress relief protocols: music-guided entrainment, breath work, active meditation, journaling20:15 Somatic breath work in practice; rapid emotional release21:00 Best fats and how Dr. W screens with food-sensitivity testing first23:15 Keto cycles for prevention: 6-week blocks a couple times per year24:15 Exercise as mitochondrial medicine: HIIT + resistance for biogenesis and cancer risk reduction26:00 The KetoPet model: ketogenic diet + HBOT + interval training; lessons for humans28:15 Starting movement in late-stage cases; meeting people exactly where they are30:15 “Press–Pulse” strategy: what stays constant vs. what's pulsed to outsmart tumor adaptation32:00 Repurposed meds (e.g., metformin, doxycycline) and why many oncologists can't step outside SOC33:00 Bridging care: when surgery/chemo/radiation have a role; aiming at cancer stem cells37:15 Hyperbaric oxygen therapy (HBOT): driving O₂ into cells; why it's pulsed and protocol-specific39:30 Outcomes Dr. W sees most consistently: better quality of life, often longer survival41:00 The psychology of prognosis; belief, stress, and manifestation43:00 The “placebo” as your body's own pharmacy (parasympathetic healing state)44:15 Targeting glutamine along with glucose; where evidence stands now (e.g., berberine, exercise, stress)46:45 The Seven Pillars of Health overview (self-audit)48:30 Pillar 1 — Sleep: deep/REM, how you feel on waking49:15 Pillar 2 — Body: strength,...
„The Testament of Ann Lee” w reżyserii Mony Fostvold z Amandą Seyfried w roli głównej podbił festiwal filmowy w Wenecji. Poprzez muzykę i taniec opowiada o XVIII-wiecznej mistyczce, która założyła radykalny Kościół szejkersów.Autorka: Adriana ProdeusArtykuł przeczytasz pod linkiem: https://www.vogue.pl/a/the-testament-of-ann-lee-recenzja-filmu
Telluride & Venice first reactions are finally here, and rave reviews have hit for Hamnet, Dwayne “The Rock” Johnson, The Testament of Ann Lee, Adam Sandler, No Other Choice, Julia Roberts, Springsteen: Deliver Me From Nowhere, Greta Lee, and so many more. VENICE & TELLURIDE REACTIONS (Including Reviewing the Reviewers): Jay Kelly + M1's Headline for the Episode - 2:00 . Supporting Actor Category Snapshot - 8:11 . Bugonia + Our Trailer 2 & Poster Review - 12:02 Hamnet, the Big 3 in Best Picture right now + Our Trailer Review - 16:48 . Lead Actress Category Snapshot - 23:14 . Springsteen: Deliver Me From Nowhere & M1's Born To Run Fantasy - 25:43 Ballad of a Small Player & why we're predisposed to love Colin Farrell in this - 32:09 Tuner includes a starmaking performance per NBP - 34:16 After the Hunt took a beating, but could Julia Roberts still get a nom? - 36:08 No Other Choice is great, but non-werewolf loving critics are a problem - 40:47 Frankenstein, another disappointing masterpiece from GDT (?!?!) - 45:27 Late Fame might be another Greta Lee showcase - 51:48 Father Mother Sister Brother & the ovation rule almost gets dealt with - 53:41 The Wizard of the Kremlin & ovations that don't fit the tomato score - 56:48 La Grazia, Venice's Opening Night film puts our rule to the test - 58:54 The Smashing Machine & Dwayne “The Rock” Johnson's big Venice moment - 1:00:20 . Lead Actor Category Snapshot - 1:02:51 . Supporting Actress Snapshot - 1:06:17 . The Testament of Ann Lee & suspicions re: unexpected musicals - 1:08:34 Cover-Up & a new Doc Feature contender - 1:13:43 . Holdovers from Cannes, Sundance, & Berlin including It Was Just An Accident, Sentimental Value, Train Dreams, Blue Moon, Nouvelle Vague, The History of Sound & The Secret Agent + its trailer review - 1:14:41 . Venice & Cannes Standing Ovations Tally - 1:18:45 . OUTRO: 1:20:49 Upcoming Venice & TIFF schedules + Words of Wisdom involving stopwatches that beep or not. If you enjoy our show, please help spread the word. You can rate, review, like, subscribe, and follow us via all these links here. https://linktr.ee/mikemikeandoscar
What if cancer isn't primarily a genetic disease — but a metabolic one? In this groundbreaking conversation, Professor Thomas N. Seyfried, PhD (Boston College), author of Cancer as a Metabolic Disease, joins Ralph W. Moss, PhD and Ben Moss to discuss the Mitochondrial and Metabolic Theory of Cancer — and why it challenges decades of conventional thinking. Dr. Seyfried explains how cancer cells depend on glucose and glutamine as their dual fuel supply — and how cutting off both pathways may be the key to shutting cancer down. He details the role of the Glucose Ketone Index (GKI), nutritional ketosis, and new interest in anti-parasitic drugs like fenbendazole and mebendazole, which appear to target cancer's energy metabolism. This episode explores: Why the somatic mutation theory no longer explains cancer's true origin How mitochondrial dysfunction drives tumor growth The critical role of glucose and glutamine fermentation in sustaining cancer cells Why targeting both fuels together is essential for effective therapy Emerging research on fenbendazole, mebendazole, and DON as tools in metabolic therapy The potential of a paradigm shift in oncology — from genes to metabolism Resources: This Podcast contains many scientific terms. To assist our readers in understanding them, we have created this glossary. The article with links, resources and full transcript can be found here: https://themossreport.com/s5-e13-prof-thomas-seyfried-mitochondrial-metabolic-theory/ Direct link to The Warburg hypothesis and the emergence of the mitochondrial metabolic theory of cancer https://link.springer.com/content/pdf/10.1007/s10863-025-10059-w.pdf In the Journal https://link.springer.com/article/10.1007/s10863-025-10059-w Mitochondrial Substrate-Level Phosphorylation as Energy Source for Glioblastoma: Review and Hypothesis Christos Chinopoulos & Thomas N. Seyfried Paper https://www.tandfonline.com/doi/epdf/10.1177/1759091418818261?needAccess=true (PDF) https://www.tandfonline.com/doi/full/10.1177/1759091418818261 Christos Chinopoulos https://semmelweis.hu/english/2019/09/my-university-dr-christos-chinopoulos-and-the-rppa-facility/ Therapeutic benefit of combining calorie-restricted ketogenic diet and glutamine targeting in late-stage experimental glioblastoma https://pubmed.ncbi.nlm.nih.gov/31149644 Glucose Ketone Index Calculator Post https://pmc.ncbi.nlm.nih.gov/articles/PMC4367849 Spreadsheet with calculator https://pmc.ncbi.nlm.nih.gov/articles/instance/4367849/bin/12986_2015_9_MOESM1_ESM.xlsx Sam Apple - Ravenous https://amzn.to/4nr6YMP
Access the FREE Water Fasting Masterclass Now: https://www.katiedeming.com/the-healing-power-of-fasting/What lifestyle choices can reduce your risk before cancer develops? (Video ReRelease)Dr. Katie Deming sat down with Dr. Thomas Seyfried, professor of biology at Boston College and author of Cancer as a Metabolic Disease. Together, they explore how cancer cells depend on sugar and glutamine for fuel, why the mitochondria, not DNA mutations, may be at the heart of the disease, and what this understanding means for prevention and treatment.Key Highlights:Can dietary changes, fasting, and exercise support treatment once cancer is diagnosed? Why should patients and doctors pay attention to the Glucose Ketone Index (GKI) to measure how the body is fueling itself?What can you do today to reduce your risk of chronic illness?Dr. Seyfried explains the Warburg Effect, the role of dysfunctional mitochondria in cancer growth, and why standard treatments may sometimes work against us by feeding cancer's energy needs.Listen, learn the surprising story of how weight loss, not a new drug, led to dramatic tumor reduction in lab studies. Dr. Thomas Seyfried: https://www.bc.edu/bc-web/schools/morrissey/departments/biology/people/faculty-directory/thomas-seyfried.htmlAccess the FREE Water Fasting Masterclass Now: https://www.katiedeming.com/the-healing-power-of-fasting/ Transform your hydration with the system that delivers filtered, mineralized, and structured water all in one. Spring Aqua System: https://springaqua.info/drkatieMORE FROM KATIE DEMING M.D. Save your spot for the next LIVE fasting call here: https://www.katiedeming.com/the-healing-power-of-fasting/ Work with Dr. Katie: www.katiedeming.comEmail: INFO@KATIEDEMING.COM 6 Pillars of Healing Cancer Workshop Series - Click Here to Enroll Follow Dr. Katie Deming on Instagram: https://www.instagram.com/katiedemingmd/ Please Support the Show Share this episode with a friend or family member Give a Review on Spotify Give a Review on Apple Podcast DISCLAIMER: The Born to Heal Podcast is intended for informational purposes only and is not a substitute for seeking professional medical advice, diagnosis, or treatment. Individual medical histories are unique; therefore, this episode should not be used to diagnose, treat, cure, or prevent any disease without consulting your healthcare provider.
Episode 2672 - BEST OF: Vinnie Tortorich welcomes Dr. Thomas Seyfried and they discuss metabolic dysfunction, glucose, glutamine, and cancer therapies. https://vinnietortorich.com/2025/07/glucose-glutamine-cancer-dr-thomas-seyfried-episode-2672 PLEASE SUPPORT OUR SPONSORS YOU CAN WATCH THIS EPISODE ON YOUTUBE - Glucose, Glutamine, and Cancer Vinnie explains why he recommends listening to Dr. Thomas Seyfried. (2:00) Vinnie has been in remission and avoided chemo for 17 years by leading a ketogenic lifestyle. There are all kinds of side effects from chemotherapy, even though it can save people. There have been several theories of disease. (8:00) NCI states that cancer is a genetic disease of dysregulated cell growth, called the somatic mutation theory. Another theory suggests that damage to organelles can cause mutations in cells, or that mutations may have a mitochondrial metabolic origin. The treatment of cancer as a metabolic disease also allows people to participate in the management of their disorder. He explains the importance of oxygen and energy and how they affect the cells. (11:00) This is known as the mitochondrial metabolic theory of cancer. Dr. Seyfried explains some fascinating experiments and theories. (14:00) Once there is an agreement on the mitochondrial metabolic theory, treatment for cancers could be much less toxic and more manageable. (17:00) Metabolically treating cancer can help because even if there is recurrence, it can often be treated with fewer chemicals. (20:00) The idea is to reduce or eliminate the cancer through diet and medication that target the fermentation metabolism. Glutamine is an amino acid and has many uses in the body. (22:30) Dr. Seyfried explains the press-pulse therapeutic strategy. The Glucose Ketone Index What kind of diet and supplementation can help those who may have cancer? (27:30) The Glucose Ketone Index (GKI) calculator and its function are explained. How the GKI happens varies per person, but if you can keep the GKI measurement at 2.0 mmol or below, you can put pressure on the tumor cells. (29:00) Each person is their own experiment, but low-carb is beneficial as it keeps your ketones active. Vinnie asks Dr. Seyfried to explain ketone measurements and monitors. (32:30) They discuss genetics, such as the BRCA1 mutation. (36:00) They discuss the frustration of some doctors' approaches to other diseases. (40:00) Type 2 diabetes has replaced smoking as the number one risk factor for cancer! (43:15) They discuss the challenges of today's diet and lifestyle. (46:00) Low-cost and convenience foods are taking their toll on society's health. Type 2 diabetes is a diet and lifestyle issue. Give people the opportunity to make their own choices. Many doctors need to be re-educated, and people need to know all their options. (50:30) Processed food and glucose are a highly addictive force on the brain. (51:00) Dr. Seyfried is a professor who shares information about and is developing a protocol, which he hopes will be available soon. His website is: More News If you are interested in the NSNG® VIP group is currently closed for registration, but you can get on the wait list - Don't forget to check out Serena Scott Thomas on Days of Our Lives on the Peacock channel. “Dirty Keto” is available on Amazon! You can purchase or rent it . Make sure you watch, rate, and review it! Eat Happy Italian, Anna's next cookbook, is available! You can go to You can order it from . Anna's recipes are in her cookbooks, website, and Substack–they will spice up your day! Don't forget you can invest in Anna's Eat Happy Kitchen through StartEngine. Details are at Eat Happy Kitchen. PURCHASE DIRTY KETO (2024) The documentary launched in August 2024! Order it TODAY! This is Vinnie's fourth documentary in just over five years. Visit my new Documentaries HQ to find my films everywhere: Then, please share my fact-based, health-focused documentary series with your friends and family. Additionally, the more views, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! PURCHASE BEYOND IMPOSSIBLE (2022) Visit my new Documentaries HQ to find my films everywhere: REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere:
In this episode of Death Clock, Brent talks with Dr. Thomas Seyfried, an impassioned biologist and leading voice in the metabolic theory of cancer. Seyfried argues that the origins of cancer lie not in mutations, but in dysfunctional mitochondria, and that treating cancer as a metabolic disease opens the door to radically different therapies. They explore the promise and pitfalls of ketogenic diets, fasting, and metabolic interventions, and challenge conventional thinking on everything from chemo to cancer screening. Hope you enjoy.
Merriam-Webster's Word of the Day for July 13, 2025 is: contrite kun-TRYTE adjective Contrite is a formal adjective used to describe someone who feels regret for their bad behavior, or something, such as an apology, that shows such regret. // Although the mayor appeared contrite about the most recent scandal plaguing city hall, many constituents remained unpersuaded. See the entry > Examples: “At the restaurant, late into the meal, ‘Honey, Honey,' from the ‘Mamma Mia' soundtrack began to play, with [Amanda] Seyfried's 22-year-old voice issuing through the restaurant's speakers. The waitress came over, contrite. The song was just part of the usual play list. ‘Listen, I love having a stake in pop culture,' Seyfried reassured her. ‘It's really nice.'” — Alexis Soloski, The New York Times, 11 Mar. 2025 Did you know? Props to Elton John: sorry really does seem to be the hardest word. But saying it (in something other than a nonapology, of course) is an important part of being contrite—that is, feeling or showing sorrow and remorse for one's bad behavior. Contrite traces back to the Latin verb conterere, meaning “to pound to pieces,” “to crush, “to wear out or down,” or “to exhaust mentally or physically.” In Medieval Latin—the Latin used in Medieval times especially for religious or literary purposes—conterere came to mean “to crush in spirit with a sense of one's sin,” or “to render contrite.” Anglo-French speakers borrowed a form of the verb conterere and made it the adjective contrit, which was in turn adopted into English in the 1300s.
In this compelling episode, Dr. Vera Tarman interviews Dr. Thomas Seyfried, a pioneer in the field of cancer metabolism. Dr. Seyfried challenges the mainstream view of cancer as a genetic disease and presents strong evidence that cancer is fundamentally a mitochondrial metabolic disorder. Dr. Thomas N. Seyfried is a distinguished American biologist and professor at Boston College, renowned for his pioneering work in cancer metabolism. With a Ph.D. in Genetics and Biochemistry from the University of Illinois, Urbana, and postdoctoral training in neurochemistry at Yale University School of Medicine, Dr. Seyfried has dedicated his career to exploring the metabolic underpinnings of cancer and other neurological diseases. Dr. Seyfried is best known for his groundbreaking book, Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer (2012), where he presents compelling evidence that cancer is primarily a mitochondrial metabolic disorder rather than a genetic one. This perspective builds upon the early 20th-century findings of Otto Warburg, who observed that cancer cells rely heavily on fermentation for energy production, even in the presence of oxygen—a phenomenon known as the Warburg effect. Dr. Seyfried's research suggests that targeting cancer's metabolic dependencies, such as glucose and glutamine, through dietary interventions like the ketogenic diet, could offer non-toxic therapeutic strategies. We explore: How cancer cells fuel themselves differently from healthy cells The connection between sugar, ultra-processed foods (UPFs), and cancer growth The Warburg Effect and the roles of glucose and glutamine in tumor development Whether refined sugar is carcinogenic like tobacco Why Dr. Seyfried believes ketogenic diets and caloric restriction can be powerful cancer therapies How his views align with metabolic psychiatry (Dr. Chris Palmer's Brain Energy) The controversial yet promising approach of "press-pulse" therapy The potential for preventing cancer through dietary change Follow: https://www.bc.edu/bc-web/schools/morrissey/departments/biology/people/faculty-directory/thomas-seyfried.html https://tomseyfried.com The content of our show is educational only. It does not supplement or supersede your healthcare provider's professional relationship and direction. Always seek the advice of your physician or other qualified mental health providers with any questions you may have regarding a medical condition, substance use disorder, or mental health concern.
Prof. Thomas Seyfried is a professor of biology at Boston College and a leading researcher in cancer metabolism. He is best known for his book Cancer as a Metabolic Disease, where he argues that cancer is primarily caused by mitochondrial dysfunction rather than genetic mutations. Seyfried holds a Ph.D. in Genetics and Biochemistry and completed postdoctoral training in neurology at Yale University. His research focuses on metabolic therapies, including ketogenic diets, as potential treatments for cancer and neurological disorders. He has published over 150 scientific papers and is a prominent advocate for rethinking conventional cancer treatment approaches.In our conversation we discuss:(00:00) – Why cancer rates are doubling(06:54) – The real root cause of cancer and evolving treatments(13:07) – Why we believed cancer was mostly genetic(20:52) – The role of mitochondria in preventing cancer(25:54) – Did our ancestors get cancer? Lifespan vs. risk(28:46) – Lessons from the Inuit diet(31:42) – What's the optimal diet for cancer prevention?(42:05) – Understanding and measuring your GKI(46:12) – Intermittent fasting vs. prolonged fasting(55:32) – Cancer treatments and key supplements to know(58:26) – The role of NAD precursors in recoveryLearn more about Prof. SeyfriedUniversity profile - https://www.bc.edu/bc-web/schools/morrissey/departments/biology/people/faculty-directory/thomas-seyfried.htmlBook - https://www.amazon.com/Cancer-Metabolic-Disease-Management-Prevention-ebook/dp/B00852YXZS?ref_=ast_author_mpbWatch full episodes on: https://www.youtube.com/@seankimConnect on IG: https://instagram.com/heyseankim
Send us a textShort Summary: Cancer's metabolic roots with Dr. Thomas Seyfried.About the guest: Thomas Seyfried, PhD is a professor of biology at Boston College. He has researched cancer metabolism, epilepsy, and lipid biochemistry for over 40 years.Note: Podcast episodes are fully available to paid subscribers on the M&M Substack and everyone on YouTube. Partial versions are available elsewhere. Transcript and other information on Substack.Episode Summary: Dr. Thomas Seyfried discusses the mitochondrial metabolic theory of cancer, challenging the dominant somatic mutation theory. He explores how cancer cells rely on fermentation due to defective oxidative phosphorylation, drawing on Otto Warburg's work. Seyfried explains how ketogenic diets and nutritional ketosis can starve cancer cells by limiting glucose and glutamine, while sharing evidence from nuclear transfer experiments and clinical studies. The conversation also covers environmental factors driving cancer and the importance of metabolic flexibility for prevention.Key Takeaways:Cancer is characterized by dysregulated cell growth, but Seyfried argues it stems from mitochondrial dysfunction, not just genetic mutations.Cancer cells ferment glucose & glutamine, unable to use fatty acids or ketones, making ketogenic diets a potential therapeutic tool.Nuclear transfer experiments show cancer traits reside in the cytoplasm, not the nucleus, challenging the somatic mutation theory.Environmental factors like processed foods, stress, and poor sleep disrupt mitochondrial function, increasing cancer risk.Seyfried's glucose-ketone index helps monitor metabolic states to manage cancer & chronic diseases.Cancer rates are rising in younger people, possibly due to obesity, inflammation, and environmental toxins.Metabolic flexibility, cycling between ketosis and carb-based states, may mimic ancestral patterns and reduce chronic disease risk.Related episode:M&M #215: Cancer Metabolism: Sugar, Fructose, Lipids & Fasting | Gary PattiSupport the showAll episodes, show notes, transcripts, etc. at the M&M Substack Affiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off. Readwise: Organize and share what you read. Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase. KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription. MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off. For all the ways you can support my efforts
“You see bald-headed people who have been treated for cancer. ‘You're trying to kill cancer cells, why the hell are you going bald?'”The provocative rhetorical question is asked by professor Thomas Seyfried, whose research at Boston College will revolutionize our understanding of cancer and other chronic diseases.“Metabolic therapy kills cancer cells and keeps your hair”, he says.“People are being brutalized by the system. They're being treated by people who don't know the biology and biochemistry behind the disease.”“Cancer is not a genetic disease, it's a metabolic problem. The reason everybody says it's a genetic disease is confirmation bias. It's been hammered into everybody's brain”, Seyfried says.We can see that conventional oncology is not addressing the right problem, because the death rates aren't dropping the way they should, he points out."The promise of the gene theory has not come to fruition, nor will it ever do. Meanwhile, thousands of people are dying every day. It's the greatest tragedy in the history of medicine."Thomas Seyfried does not dismiss conventional methods like radiation and chemo, but the problem is that those are being employed first, when they should be employed last.Seyfried contends that cancer is “a remarkably simple disorder” when you understand the biology. But we have made it complicated and mysterious by focusing on downstream phenomena instead of the actual cause, metabolic dysfunction.“You really have to work hard to get your body to get cancer”, he says.“Our paleolithic ancestors and those who live according to traditional ways rarely have cancer. Animals in nature rarely have cancer.”“Before antibiotics and orthopedic surgeons we died from injuries and infections. What's killing us now, whether it's dementia, cancer, cardiovascular disease or diabetes, is civilization itself.”Which means: Not exercising, being under stress, having poor sleep and eating ultra-processed food (sometimes food-like substances).Our bodies become less and less capable of using oxygen to generate energy. Cells resort to fermentation, like cells in primitive life forms once did. This is the crux of the matter. When cells switch from oxygen to glucose (a sugar) and glutamine (an amino acid) to generate energy, they become cancer cells.The solution? Starving the tumor.German doctor Otto Warburg discovered the metabolic mechanism behind dysregulated cell growth already a century ago. But other theories outmaneuvered his findings.Before rediscovering Warburg's theory and improving it, Thomas Seyfried was “just as indoctrinated as everybody else”, he says.Seyfried and his colleagues developed a diet-drug combination to destroy tumors by doing away with the detrimental fuels glucose and glutamine.A low-carb, high fat diet plus fasting targets glucose (healthy cells can burn fatty acids and ketone bodies, cancer cells cannot), and a “press-pulse” method including certain repurposed anti-parasite drugs targets glutamine. Add exercise.Patients can keep track of the levels of glucose and ketones in their blood with a simple device.“We're getting longer and longer survivors for the so-called terminal cancers.”One big obstacle to getting established medicine to rethink is that there is no money in metabolic therapy. There's no pill or shot for Big Pharma to sell. But Seyfried is optimistic:“When you educate people in certain ways and make certain products that will keep the entire body healthy, this will be a new industry. It's coming.”Seyfried's research at Boston CollegeIHMC Lecture by Seyfried
I’m going to beat this cancer or die trying. Actor Michael Landon Clips Played: Peggy that’s the recipe for mustard gas (original in pinned and desc.) (youtube.com) This study DOUBLED cancer survivorship, challenging 100 years of treatment methodology. (youtube.com) Chemical Weapons of WW1 – Horrific Weapons of War – No1 – […] The post NEW: Dr. Seyfried -Radiation and Steroids ALSO Drive Sugar HIGHER- Tumor Growth. Mustard Gas & Chemo. Procedures to Make It WORSE, Not Better. No Improvement or Change in Cancer Treatment 100 Years. Wonder Why? Dr. Cornelius Rhoads and Puerto Rico. appeared first on Psychopath In Your Life.
Cancer is one of the most terrifying illnesses of our age - a sudden change that happens silently inside our bodies and slowly eats away at us until there's nothing left. It's also one of the biggest failures of the pharmaceutical age - somewhere between 90 and 97% of all cancer drugs fail at clinical trials. Which is why we're unbelievably excited to bring you our conversation with Dr. Thomas Seyfried, Professor of Biology at Boston College who appears to be hot on the trail of a cure cancer that has nothing to do with the oncology-industrial-complex. According to the dozens of papers he and his colleagues have published over the last few decades, a strict ketogenic diet coupled to a glutamine inhibitor is sufficient to weaken cancer cells to the point that the immune system can actually clear the tumor. A recent paper from his group published in February of 2025 shows the stunning effects of his protocol in a small group of eighteen glioblastoma patients. Median survival for these patients for the last hundred years has been 12-15 months, but with Seyfried's intervention appears to have been extended up to 84 months. That's seven years, for those keeping score.We sit down with Seyfried to take apart his protocol, why it works for cancer, why no one's heard if it, and how everyone has completely misunderstood what cancer actually is.MAKE HISTORY WITH US THIS SUMMER:https://demystifysci.com/demysticon-2025PATREON https://www.patreon.com/c/demystifysciPARADIGM DRIFThttps://demystifysci.com/paradigm-drift-show(00:00) Go!(00:07:33) - Reception of Metabolic Cancer Research(00:10:05) - Breakthrough in Glioblastoma Treatment(00:14:49) - Glutamine-Glutamate Cycle in Cancer(00:16:33) - Challenges and Critiques of Standard Care(00:17:43) - Barriers to Implementing Metabolic Therapies(00:24:19) - Radiation and Cancer Treatment(00:26:07) - Metabolic Approach to Cancer(00:27:30) - Evolutionary Biology's Role in Understanding Cancer(00:28:52) - Mitochondria's Role in Cellular Destiny(00:31:39) - The Oxidative Phosphorylation Process(00:35:28) - Cancer and Mitochondrial Function(00:38:43) - Cellular Electrochemical Gradients(00:41:30) - Cancer's Dependency on Fermentable Fuels(00:45:08) - Glutamine's Role in Cancer Treatment(00:52:11) - Patient Compliance and Dietary Challenges(00:55:33) - Glucose Ketone Index for Health Monitoring(01:06:48) - Fenbendazole and Cancer Research(01:10:02) - Medical Industry Business Models(01:13:27) - Diets and Nutritional Ketosis(01:17:06) - Metabolic Variability and Personalization(01:19:25) - Exercise and Metabolic Health(01:23:43) - Historical Misconceptions in Cancer Treatment(01:26:21) - Obesity and Cancer Prevention(01:28:00) - Metabolic Theories of Cancer(01:47:18) - Metastatic Cancer Origins(01:55:24) - Therapeutic and Collaborative Approaches(01:59:57) - Practical Steps and Transformations#CancerResearch, #glioblastoma, #CancerAwareness, #Oncology, #CancerTreatment, #CancerSurvivor, #FightCancer, #EndCancer, #CancerSupport, #ClinicalTrials, #CancerWarrior, #BeatCancer, #CureCancer, #CancerFighter, #StayStrong, #CancerCommunity, #philosophypodcast, #sciencepodcast, #longformpodcast ABOUS US: Anastasia completed her PhD studying bioelectricity at Columbia University. When not talking to brilliant people or making movies, she spends her time painting, reading, and guiding backcountry excursions. Shilo also did his PhD at Columbia studying the elastic properties of molecular water. When he's not in the film studio, he's exploring sound in music. They are both freelance professors at various universities. SOCIAL: - Discord: https://discord.gg/MJzKT8CQub- Facebook: https://www.facebook.com/groups/DemystifySci- Instagram: https://www.instagram.com/DemystifySci/- Twitter: https://twitter.com/DemystifySciMUSIC: -Shilo Delay: https://g.co/kgs/oty671
Amanda Seyfried is more than just that girl in MEAN GIRLS or that singing heroine in MAMMA MIA, or the even the Hollywood legend in MANK. No, Seyfried keeps pushing into new areas and her latest, LONG BRIGHT RIVER, shows yet another side of this huge talent. Here she talks to Josh about all of it including why she passed on a giant Marvel role and why missing out on WICKED had a big silver lining. UPCOMING EVENT! Nathan Lane -- March 20th in New York -- Tickets here Paul Feig -- April 6th in Miami -- Tickets here! C2E2 events in Chicago April 12th -- Tickets here! SUPPORT OUR SPONSORS! Quince -- Go to Quince.com/happysadco for 365 day returns and free shipping! Check out the Happy Sad Confused patreon here! We've got discount codes to live events, merch, early access, exclusive episodes, video versions of the podcast, and more! To watch episodes of Happy Sad Confused, subscribe to Josh's youtube channel here! Learn more about your ad choices. Visit podcastchoices.com/adchoices
This episode is brought to you by Levels, Bon Charge, and Ollie, For years, many have believed that cancer is primarily genetic or just bad luck, but emerging research suggests we have far more control over our risk than previously thought. Dr. Thomas Seyfried's groundbreaking work reframes cancer as a metabolic dysfunction, focusing on its root cause rather than just treating symptoms. While controversial, this approach offers new hope for both practitioners and patients seeking alternative strategies for prevention and treatment. Today on The Dhru Purohit Show, we're bringing you a special compilation episode featuring Dhru's conversations with Dr. Thomas Seyfried and experts from the Hippocrates Research Foundation, a nonprofit dedicated to continuing Dr. Seyfried's work by educating cancer patients on metabolic-based treatment approaches. Dr. Seyfried explores the role of oxidative stress, mitochondrial health, and glucose in cancer development and progression, along with his research on ketogenic diets as a promising solution to correct these imbalances. Den Stacey shares his journey of seeking guidance from the Hippocrates Research Foundation—ultimately becoming cancer-free. The Hippocrates Research Foundation team—Daniel Orrego, Dr. Gregory Howard, and Dr. Michelle Howard—discuss their research and their approach to guiding cancer patients by implementing a protocol designed to starve cancer while fueling the body. Dr. Thomas Seyfried is an American professor of biology, genetics, and biochemistry at Boston College. With over 150 peer-reviewed publications, his research focuses on the mechanisms driving cancer, epilepsy, and neurodegenerative diseases, as well as the role of calorie-restricted ketogenic diets in their prevention and treatment. He is the author of Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer and serves on the editorial boards of Nutrition & Metabolism, Neurochemical Research, Journal of Lipid Research, and ASN Neuro. In this episode, Dhru and his guests dive into: The role of mitochondrial dysfunction in cancer (04:05) The promise of the ketogenic diet and its impact on cells (09:58) How the ketogenic diet cuts off cancer's fuel sources (20:37) Den Stacey's email about his experience with Dr. Seyfried's protocol (26:54) The Press-Pulse protocol used in Den's treatment (30:25) The role of stress reduction as a key part of the protocol (35:31) The benefits of hyperbaric oxygen therapy (38:53) Why pharmaceutical drugs and diet should be used in concert (40:47) What an ideal cancer treatment team looks like (46:31) Testing and evaluating the protocol in real-world cases (56:39) Recognizing the success of the case study and the next steps (59:42) Final thoughts (01:02:01) Also mentioned: Full episode with Dr. Thomas Seyfried Full episode with Den Stacey This episode is brought to you by Levels, Bon Charge, and Ollie, Right now, Levels is offering my listeners an additional 2 FREE months of the Levels annual Membership when you use my link, levels.link/DHRU. Make moves on your metabolic health with Levels today. Right now, BON CHARGE is offering my community 15% off; just go to boncharge.com/DHRU and use coupon code DHRU to save 15%. Want to give your dog the best in clean eating? Take the online quiz and introduce Ollie to your pet. Right now, Ollie is offering 60% off your first box of meals when you subscribe today! Just head to Ollie.com, use the code DHRU and you'll get 60% off your first box of meals in your subscription. Learn more about your ad choices. Visit megaphone.fm/adchoices
Filmmaker Atom Egoyan ("Exotica", "The Sweet Hereafter") returns after 9 years for his third appearance on the podcast. He has a new movie that is currently in theaters called "Seven Veils" starring Academy Award® nominee Amanda Seyfried ("Mean Girls", "Mama Mia"). The film follows theater director Jeanine (Seyfried) who, after years away, re-enters the opera world to stage her former mentor's most famous work. Haunted by dark and disturbing memories from her past, Jeanine allows her repressed trauma to color the present as her personal and professional lives begin to unravel. Renowned director Atom Egoyan sees "Seven Veils" as operating within a trilogy alongside his other critically acclaimed works "Exotica" and "The Sweet Hereafter". In "Seven Veils", he also reunites with Seyfried, who he worked with on the 2009 film "Chloe", in this visually stunning, propulsive work, filmed on location during the staging of his acclaimed production of "Salome". Egoyan directed the opera "Salome" in 1996, the first opera in what would be many to come over his career. Best known as a prominent film director since the 1980s, Egoyan has proven he is a master of both mediums, and "Seven Veils" is his way of bringing both together. Also on this episode the Canadian filmmaker Jeffrey St. Jules ("Bang Bang Baby") discusses his new film "The Silent Planet". The film stars the great actor Elias Koteas ("Exotica", "Crash") who joins us in this conversation. Serving a life sentence alone on a distant planet, an aging convict must confront his past when a new prisoner arrives and forces him to remember his life on Earth.
Former Oklahoma Rep Sherrie Conley joins me to discuss a couple of education related bills. SB 224 and HB 1491. SB224 would establish a Statewide Longistudinal Data System in the state of Oklahoma. This would allow the govermnment to track and monitor your child from cradel to the grave. I have a big problem with this! Listen and you'll understand why. Then, we have HB1491 and this interesting move by Gov Stitt with support from Speaker Hilbert and Pro Temp Paxton. They want to allow any of the board members to participate in setting the agenda for the OSDE. Maybe this would not seem so interesting, if it were not on the heals of Gov Stitt's recent move to remove three board members and replace them with three members that some have suggested are closely aligned with Stitt. Is this a hotile takeover to wrest control from Superintendent Walters and prevent him from trying to count children of illegal immigrants? Or is it an honest move to redistribute power? We'll lay out some facts, and you can decide. Transcript: Jake How do you feel about surveillance? How do you feel about surveying your children or the state surveying your children? We're talking about data mining. It is a topic of one particular bill here in the Oklahoma legislature. We're gonna take a look at it. I'm here with Sherry Connolly and will also look at house bill 149 1 that was recently backed by Governor Stitt and the speaker of the house. This deals with a shake up in the school board here in Oklahoma so got a lot to get to let's get to it. All right, I'm here with the former house representative Sherry Connolly Sherry welcome to the show Sherrie Conley Thank you so much for having me You You bet. Well I appreciate you all the work you have done and are doing in the state. Before we get too involved in these subjects that I wanna dive into both this idea of data mining collecting information on our children in the state and also this house bill 1491. I want to give you a chance to talk about a passion project of yours. Exposing the corruption in the public schools. Real quickly, what is the website that you are working on? Sherrie Conley So we have we have two websites one is our broken trust website it's still in the construction phases but we've got another one that we're taking over called iHeart my teacher You OK Sherrie Conley .org. It is a collection of over 24, 000 reports of a teacher misconduct the majority of it is all sexual misconduct and so. Yeah, it's like it's a huge undertaking. We got to update it. I believe the gentleman that has it that we're taking it from. He worked for about four years doing it and just got overwhelmed with all of the information and so yeah we we got a lot of work ahead of us, but it's iHeartmyteacher.org You You know someone would ask, “is this actually happening in our schools?” and I think that's the right I mean that is eye-opening that the one who founded this to track this and expose it he's overwhelmed because of all of the data that he's he's collecting and all of the instances of sexual misconduct in our schools so yeah, it's definitely happening Sherrie Conley It is definitely happening and I have collected it over the last year and a half while really just a year started my research in February of last year collecting the data. I got 2 6 3 predators from inside the school and those are just Oklahoma cases those are just predators from inside You Wow Sherrie Conley Oklahoma. You Well, that is iHeart my teacher .org the other one broken trust you're working on but that's gonna be coming to everyone pretty soon and I just wanted to make sure we we highlighted that before we get into these other conversations and forget to because I really appreciate your work there. I think it's needed in the state. Sherrie Conley Yeah, thank you You But the topic today we're looking at this statewide longitudinal data systems. The SLDS this is something that looks like it's been adopted by about 40 states and often times that's used as an argument for for something to adopt it and if we see a trend across the nation then often times Oklahoma says well it's happening everywhere else we want to happen here too, but we want to hit the pause button on that and say wait a minute is this a good idea? To actually track the data on our students what have you seen Sherry about this SLDS in our US concerned about it as I am Sherrie Conley I am extremely concerned about it and let me just kind of give you just a little piece of information. This started in Oklahoma back in 20 12 Oklahoma received a $4.99 million grant. For the race to the top program to institute a longitude that system and that money good for the year 2012 to 20 17 I haven't that information just came to me, but I have not had an opportunity to dig into that and what was instituted whenever that money was received? You Well, back in 20 12 Sherrie Conley Yes You OK, do you know where this is originating from? I mean, who is behind this and pushing this as far as wanting schools to adopt us Sherrie Conley No, I asked the house author where the language came from and he's he's not real sure where it came from but he knows that it's being pushed by the education people in Oklahoma and also by the chambers and so you know if you look at The language inside the bill it gives the workforce commission higher education, career tech superintendent, public instruction, Oklahoma, employment security commission oh QA and the the university it's the Russo group. It gives them all access to the data that comes out of the database. Me personally it also add some language in there that says among approved entities, but then it also goes down and it makes the comment that that there could be other Groups that are given access to it, and so that is the part that concerns me if this was being You Right Sherrie Conley created and used in the state of Oklahoma in order to improve education at the common end level at higher Ed workforce you know I'm getting our kids to work and getting them educated in the field that they want to pursue I would be OK with this, but I see you know connections to the agenda from the United Nations for a global database system, and that is what concerns me about this You Me too, yeah have you seen the divergent series? Sherrie Conley I have yes You Stuff like this reminds me of this, and I know that that could be laughable, but so all too often we're seeing the sci-fi fantasy world becoming reality you know, and when you have an agenda for kids when you when you wanting to mind their skills and their strengths and all these data points on them to it seems like fund them in a certain direction Sherrie Conley Yeah You And it just reminded me of that I don't know if is a divergent series or one of those I think it's called a divergent they they have certain categories that people go and Sherrie Conley Yes You select at a certain age and you know it seems like we're thinking along those lines, dude does the government really need that much data on our kids and do they need to have that much control about how to funnel them in a certain direction? Sherrie Conley Yeah, well it makes me think of the movie. I think it's ants where when the baby answer born somebody holds it up and says this is a worker aunt and hold it up and you know this is you know You Right Sherrie Conley whatever whatever the other categories are it's been a long time since I've seen the movie but that's what this kind of makes me think of is funding kids into you know well your grades are not high enough so you can't go to college so you're gonna have to go either into the military or into career tech, I feel like you know we need to be educating our kids. On all sorts of You know the arts and music, appreciation and being able to think logically and reasonably and you know create a dialogue and rhetoric and all of those things and then let the kids decide. I think that we're doing too much of deciding for the kids. I say all the time I know there's a lot of other people that that say this, but let's teach the kids what to think or how to think and not what to think you know and that's what this feels like there. This is a push You Right, right? Sherrie Conley towards is pushing kids to think this is where I'm gonna have to go because I'm not good enough to go to know to someplace else and I just I don't agree with making decisions for children. People have the freedom. They should have the freedom to be able to make the decisions on their own, we should not be collecting data points in order to push them into the direction that somebody else thinks they need to go. You Well, I'll just read here from the text of the bill again we're talking about Cinna bill 22 4 and is there is there a house bill with a different number? Sherrie Conley I have not found one You OK OK I think it's just this one. It's run by Seyfried in the Senate in Caldwell in the house and here in section a right at the beginning of the bill first page. It says the purpose of the SLDS shall be to provide state agencies, but right there first red flag provide state agencies, legislators, and other Sherrie Conley Yeah, You approved users with with that's the issue. It's very vague very open right other approved who are these approved users and who's approving them Sherrie Conley that's the Yes You It was shall provide them with access to data on early childhood education, elementary and secondary education, workforce training and employment outcomes and employment outcomes so I mean how how far are we gonna track these Sherrie Conley Yes You individuals these children it is it employment while they're in high school or is it beyond that? Sherrie Conley Well, the next word, the next four words, five words say improve education, and then here's the caveat and workforce outcomes You There you go Sherrie Conley You know here's the thing is that you have to track somebody past their high school in college careers in order to be able to track workforce outcomes right so you You Yum Sherrie Conley know that I mean they're calling it a longitudinal data system and so they are truly talking about tracking people from the cradle to the grave and determining where they go, what I see this is using this for ES G and social scores you know I just came from London and one of the perfect examples of a social credit score is the Uber system and you know you can take that system and you can you can see where using these data points where people go whether or not they're working, you know you can use gaps in their employment as they hit on their social credit score that if you're tracking their workforce your tracking their work and And everything that comes after high school in college that's exactly what that stuff can be used for You Yeah, well it's clear and it's no secret. The DEF has made it very clear that they have an agenda and you know when you start seeing things like this it seems to match what they have been very vocal about this this global Sherrie Conley Absolutely You agenda and it's so easy to dismiss this and say you know you radical conspiracy theorist talking about 15 minute cities and and social credit scores. But then we have a bill like this and it's talking about tracking from the cradle to the grave preparing people for the workforce and and here's a thing I get so sick of it because it's always for our own good. It's always about the government protecting us helping us, but it's like you said, are we telling them what to think or we just simply teaching them how to think how to be independent critical thinkers who then can go pioneer their own way rather than Sherrie Conley Yeah Yeah You fall into a certain track that has been pre- prepared for them. Sherrie Conley Yes, yeah and that is that is very concerning to me because how many people actually reinvent themselves all the time they get a degree in one thing and then you know decide I don't wanna do that and so they go to another job that's You Yeah Sherrie Conley outside of where of what they actually majored in in college and you know is that eventually going to be used against us if you look at the comparisons to the launch Tual database and to the UN agenda They have data collection and management on there, which is sharing the and the integration of the educational data for global monitoring monitoring monitoring sorry You Monitoring Sherrie Conley Privacy and security oversight then they got tracking student progress, which aligns a state level educational outcomes with the global four targets and interestingly enough it actually even has a workforce and migration data in it and it's to improve understanding of migration impact or education systems and what I find so interesting is that the argument you know I'm gonna go back to the argument between Walters and stick the argument between them was Walters, wanting to collect the data on the students who are illegal immigrants to determine the impact that they're having on Oklahoma's education system and the funding right and yet this the UN database the UN agenda is actually wanting to collect that data through these launch to databases and so I find it very interesting that they got that battle going back-and-forth between them and yet this SDS actually does exactly what Walters just wanting to do to determine the impact on our education system here in the state of Oklahoma You Yeah, I just as I read down the bill it just for me. It's more concerning. It says implement identity management capabilities, identity Sherrie Conley Yeah, what is that? You management, right to create unique identifiers that link early childhood childhood education, elementary, and secondary education post secondary education, workforce data, so we've seen those for Elements there in the previously in the bill that early childhood elementary secondary post secondary and workforce but this identity management capability What is that about and you know one thing we know Sherrie Conley No You about the UNWEF this global agenda is the big 3M's that the monitoring management and monetize Sherrie Conley Yep You and this is the goal is to monitor that's why I push back Sherrie Conley I didn't You against surveillance, especially in this day, even if it's used to justify preparing our youth for the future or use to justify catching more criminals I'm gonna be paranoid whenever we talk about Sherrie Conley Yes You surveillance because I know there's a bigger agenda here and that is the first step and Sherrie Conley Absolutely You monitoring which then when you're monitored, you can be managed and when you're managed, you can be monetized not for your Sherrie Conley Yep You benefit, but for someone else's benefit to use you Sherrie Conley Yep You as a channel and Just direct you in a certain way where you can be a good worker which where we heard that before if it rings a Marx's Sherrie Conley Yes, You tone Sherrie Conley yes well and if you think about it, these companies that are changing their human resources to human capital that gives a huge Red flag for me that you are counting me not as as as someone who is valuable to your organization, but you're counting me as an asset that I You Yeah Sherrie Conley am I am looked at as money for you to make money and I don't know they're just there's something just really creepy about that. It's kind of a weird word to use, but that is very scary to me and then the that section 4 was something that was very section 3 that was very concerning to me because when you say identity management capabilities, that is what it sounds to me like and I hope I'm wrong but what it sounds to me like is giving someone a number inside the database that will follow me kind of like my Social Security number that will follow me all of my life so that it can be tracked, regardless of where I go work and regardless, if you know what state I'm working in that it can always be tracked back to that number and that I'll have to use that along with my Social Security number so that they can identify who I am and what I'm doing. You Yum and we're talking about things like your history of illness for instance, your travel where were you Sherrie Conley Yes You exposed to other forms of illness Sherrie Conley Exactly You Behavior psychological Sherrie Conley Yes You evaluations, you know Sherrie Conley Yes You businesses you started businesses you've been affiliated with the list goes on and on and on and the ones reading this first of all, we don't even know who that Sherrie Conley It does You is because they've Sherrie Conley Right You intentionally made it vague, so who's gonna be looking at this data and how would they be evaluating you? Do you want them evaluating you and your children especially So man, so many red flags here and you know one of the things we mentioned at the start of this I think before we went live is you know Chad Colwell was carrying this in the house you know you respect Chad Caldwell in the house and we're waiting to hear back from him as far as what is it that he sees that would be good about this bill I personally don't know him well I don't know Senator Seyfried well in the Senate I know both of them have had other good pieces of legislation in the past So I'm curious to hear from them what what is it about this bill that you think would be good for Oklahoma's Sherrie Conley Yeah, I am. I am very much interested in hearing hearing from him and that's the reason why I reached out to him. I was hoping that I could get you know a response back so that we could talk about you know what he seems to be the benefit of this, but I will tell you that I'm also very concerned about this being linked to school based healthcare. I'm also very concerned about it being linked to common core and I was looking at a graphic that was put out by Jenny White and it's it's kind of a complicated graphic I I really need to sit down with her and have her explain to me yeah You I saw that graphic arrows going everywhere Sherrie Conley Yes, yes everywhere but if you look at it closely, you can see that there are different entities that are gathering data on our students at every single level and so I mean even our night test you know that are tracking our our test scores are reading in math test scores for fourth and eighth graders You know that's that's a concern to me also, I mean, I understand the need to be able to determine where our kids arming we're using that data to be able to say look our schools are not cutting it. They are failing our students and so they're failing our families and they're failing our communities and our businesses who need good you know intelligent articulate workforce so I understand that but this I believe goes way further than what anybody realizes the capabilities of this are and if this truly is connected to the UN and I noticed. Let me see I wrote some notes on it so the $4.99 million if they got in 20 12 you know what was the cost of that 4.99 million. What did the state have to give to the federal government who provided the grant money for this what were the stipulations what were the strengths and I guarantee you in looking at what they say the cost in implementing this is gonna be 2.1 to $5.1 million and again you know is this a state investment is this federal dollars I believe it says in there or something about grant money and so if anytime you connect the federal government to a data system they are going to want something for that money you can't they don't just give money away and expect you you know to just say hey thanks and then walk away. They want something for it. And to say, it says data access, she'll be granted through a formal data sharing agreement submitted to the statewide launch to database data system, government council, and you know so who who does that mean is going to get is gonna get this information it also says controlled access to approve external partners, including researchers or vendors Ensuring compliance with privacy protections, but you know what here's the thing is that if you if you have attached a number to my kid and you tracking them, I'm more concerned about that than I am you sharing you know where our kids are in math at a fifth grade level OK so if that is sharing that information Performance information outcome information with them to help them determine what they need to do with curriculum. I'm OK with that, but when you start selling the data to people who are going to use it to manage behaviors and the ability to limit our freedoms based on that data, I have a huge problem with it. You Yum Yum that money from in 20 12 where did it go? Was it was it spent on this as as the beginning laying out the infrastructure in the foundation for it that was that money spent was a set aside what happened to it? Sherrie Conley Yeah, I don't know that's a really good question and that's sad. That's gonna be my next dig to see if we can figure out you know what legislation created that I like. I said it was just given to me right before I came on the call and so You OK Sherrie Conley I am I still have yet to figure to figure that part out, but I will tell you that you can't. You can't gather all of this information and not connected to the healthcare industry and to mental health and those sort of things because. I just believe that those are data points that they will include in this and so I think I said that it was the Yeah, I didn't. I didn't see anything on there. Maybe it did say Oklahoma healthcare but I didn't put it in there. Seems like there was something in there. You Well, obviously, the big push for community schools, wraparound services, social emotional Sherrie Conley Yes, yes You learning, and you know this is very concerning to a lot of people, including myself as we are asking teachers and school administrators and possibly leaving, not even hiring outside Contractors to come in to service our children when we send them to school to learn and so we're just blowing the lines between school and every other aspect of their life is that the reason we have public schools government funded schools Sherrie Conley You know I anymore I'm I'm starting to question you know the people who are in control at the higher level not you know at the state level obviously, the majority of Oklahoma's are levelheaded, but I don't think that they are looking past What they've been told about this legislation I don't think that you know one of the things you were in the Senate and you know one of the things that we need to be thinking about as legislators is what what is the long-term goal here? What are the long-term consequences here and I think that you know people read legislation they get the lobbyist to come and talk to them and they say oh we wanna do this and this is what we're gonna do. You know what we're gonna use it for but they don't look downstream to see well upstream to see who it's coming from number one but then downstream to see what are those long-term consequences and you and I both know that there's legislation that gets past every single year that has to have cleanup language done to it because somebody didn't think about the unintended consequences. You No doubt no doubt well I'm looking at the time here. We're already at 40 minutes and try to keep these about a half hour long but that's OK. I want to let's just touch on this 1491 and we'll do a part two to dig into this little bit Sherrie Conley OK You deeper, but this is house bill 149 1 filed by speaker Hilbert with support from the pro Tim, Lonnie Paxton and Governor Stitt, and it would allow any member of the state board of education to place an item on the board agenda, if requested in writing by at least two members of the board. Now speaker, Hilbert said we have volunteer boards and commissions that play important oversight function for the for state agencies for a reason and the duly appointed members of the state board of education should have a say in the agenda before them. This has been a long-standing issue that needs to be fixed and then pro Paxton said the state board of education plays a crucial role in shaping the future of our schools and its members should have a clear and fair process for addressing key issues. This legislation ensures that every board member has a voice and setting the agenda, reinforcing transparency, and accountability in our education system he said with the current structure, the board is neutralized and has no no say in shaping policy, allowing this will provide a fair and more effective Structure. What do you think? Do you do you like this? Does it make sense to open this up for other board members to have a say in setting the agenda or do you think that that is going down a path with going back to our last argument with unintended consequences? Sherrie Conley Yeah, so that's a really great question and so my thoughts on it go to number one. The board members on the state board of education are appointed by one person and so what looks like is happening now is it's being stacked against the the chairman of the board, which is superintendent Walters to push an agenda or to reverse an agenda you know on policy that was passed prior to now that's just you know from the outside looking in that's what it looks like, but what I would say is that because all Five of the board members that sit on the state board of education are appointed by one person that creates You Can we talk about the governor? Sherrie Conley Yes, that creates a balance of power issue for me because if you look at the first six years, the governor state has been an office. He's been perfectly fine with everything that superintendent Walters has you know done with the exception of maybe a couple of issues which I believe that they have had conversations you know behind the scenes about that you know those board members they're reminded often I think who they are appointed by and who they are actually they're on the best of. And so they're reminded quite often that they are expected to carry out the governors agenda, right that's at least what it sounds like when you're reminded you this is who you work for that sounds like a threat to me and so if I'm reminded who I work for that. Sounds like they're trying to tell me you know do what I tell you to do or you're not gonna have this job anymore which looks like exactly what happened with the shake up right well You Yum Sherrie Conley now there's three new board members appointed to this board and with a fourth seat that is open. And that really looks like an opportunity for you know some some shenanigans. I'll just call them to happen within the state Board of Education now that Governor and Ryan are not agreeing on things and so I disagree with what they're trying to do but only because if he had done this at the very beginning without it looking like there's an agenda behind it then I probably would've thought. Oh yeah that's probably a good idea. But now looking at the timing of this, it looks very suspicious to me and so I'm very concerned that it's because of the immigration policy that the three members who were removed voted for And and and since that was the first question that was asked of one of the new board members was on the immigration issue, you know it looks very suspicious and it looks like there's trying to be some control there so the governor actually has control over the rules if he doesn't like the rule when it comes to his desk, he can reject it and so him trying to do this in the 11th hour of his term it really just kind of feels like there's Like I said, some shenanigans going on there You Yeah, I mean it is. It's impossible to simply dismiss how this has Sherrie Conley Yes You followed the removal of those three board members and replaced ironically with three members who seem to have connections back to it. So it's it's suspicious to me as well. The timing of this it feels like an agenda. It's interesting attorney general Drummond said Governor step promoted and supported superintendent Ryan Walters, every step of the way, even standing by the superintendent when he gave blanket approval for the miss spending of our tax dollars now that his handpick superintendent refuses to do his bidding Governor state wants to change the law to get his appointee full control of the education agenda. Sherrie Conley Yeah You So I mean, I'm not a big drum and fan but I think that he's probably right here Sherrie Conley I agree, yeah and you know if these five members of the board were elected I would feel a lot differently about it and are we going to change this policy for all school boards to wear all school school board members have the opportunity to add items to an agenda because that looks very suspicious that you are picking on one board you know we have a multitude I couldn't even tell you how many boards we have across the state and so when you are hand picking a specific board to make the changes on, but you're not including all of the other boards that have member sitting on it. It looks very suspicious and it makes me you know. Doubt that this is the right thing to do You Here with Sherry Connolly, former house rep and an educator and you've spent years in administration as well so your perspective and insight into education in general is is very respected and I appreciate your insight today Sherrie Conley Thank you so much. I appreciate you asking and giving me the opportunity to to share my thoughts on this and I hope that you know we've been able to help shed some light on that the issues of both bills and I look forward to having conversation you know you and I had had other bills that we wanted to discuss and so I look forward to You Yeah, well I said Sherrie Conley talking again with you. You thank you and I said we would do a part two on this. Maybe we covered it adequately for now but there's there's Sherrie Conley Yeah You definitely many others that we have our eyes on so yes, let's let's plan this again soon because these bills are going through quickly and some of them we wanna make sure don't go through. There's big Sherrie Conley Yes You concerns just like the one we mentioned Cita bill 224 and even this one we must Sherrie Conley Yeah You consider this what is the bill number house bill 1491 on the school board, so yeah we're gonna keep an eye on these and come back and talk about this. She appreciate you. Sherrie Conley Yes, I appreciate you too Jake. Thank you so much. You You bet all right guys we should like share and subscribe spread the word and I will see you again next time
Professor Thomas Seyfried is a professor of biology, genetics, and biochemistry at Boston College. He received a PhD in 1976 in genetics and neurochemistry from the University of Illinois at Urbana-Champaign, followed by a postdoctoral degree from Yale University in New Haven, Connecticut, in the field of neurochemistry and genetics. His field of interest is gene-environmental interactions in epilepsy and brain cancer. Dr. Seyfried's lab at Boston College focuses on studying dietary therapies for epilepsy, brain cancer, and neurodegenerative lipid storage diseases. YouTube A Novel Therapeutic Strategy For Metabolic Management of Cancer - Thomas Seyfried (June 2018) Podcast Thomas Seyfried, Ph.D.: Controversial discussion—cancer as a mitochondrial metabolic disease? (EP.30) In this episode you will discover: In this episode you will learn about the complexities of cancer and Professor Thomas Seyfried insights on cancer- how cancer research developed over the past decade, the impacts of sugar and cancer, boosting your body's defenses and navigating a cancer diagnosis. Connect more with Dr. Kiltz Website: https://www.doctorkiltz.com/ Keto + Carnivore Support - Group Kiltz Mighty Tribe: https://kiltz-mighty-tribe.mn.co/ Kiltz Cups: https://kiltzcups.com/ Doctor Kiltz Nutritional Solutions: https://www.doctorkiltznutritionalsolutions.com/ Instagram: https://www.instagram.com/doctorkiltz/ Tiktok: https://www.tiktok.com/@doctorkiltz Facebook: https://www.facebook.com/doctorkiltz Twitter: https://mobile.twitter.com/doctorkiltz Amazon: https://www.amazon.com/Robert-Kiltz/e/B005EIXDWU%3Fref=dbs_a_mng_rwt_scns_share Books by Dr. Kiltz: https://www.doctorkiltz.com/books-by-dr-kiltz/
The medical industrial complex and big insurance are wasting billions of your dollars on research and treatments for cancer as a genetic disease. Dr. Thomas Seyfried, a 40-year doctor and researcher currently at Boston College has evidence that it's a metabolic condition and can be treated. However, his protocol will not be used by indoctrinated oncologists and physicians because of their continual fear of standing up, speaking out and being in constant fear of losing their careers. Pay close attention to Dr. Seyfried and the knowledge he shares.Study/Protocol: https://patriotswithgrit.com/wp-content/uploads/2025/01/Duraj-et-al.pdf-------------------------------Check out all of our vendors at:https://patriotswithgrit.com/patriot-partners/SPONSORS FOR THIS VIDEO❤️ Cardio Miracle - Boost your energy, help support your immune system, and improve your mental clarity-plus use promo code GRIT and save 10% on your order https://cardiomiracle.myshopify.com/discount/GRIT
Professor Thomas Seyfried challenges the conventional understanding of cancer in this insightful discussion. With over 30 years of experience, Seyfried emphasizes cancer as a metabolic disorder, not a genetic disease, and explores the role of diet, lifestyle, and mitochondrial dysfunction in cancer's prevalence. Delving into topics like the ketogenic diet, glucose fermentation, and the impact of stress and environment, Seyfried offers a fresh perspective on cancer prevention and management. This episode is a deep dive into rethinking cancer's causes and solutions with potentially life-changing implications.
Professor Thomas Seyfried joins the conversation to challenge the conventional view of cancer as a genetic disease, presenting it instead as a metabolic disorder influenced by lifestyle factors. With over 30 years of research, Seyfried argues that current cancer treatments may exacerbate the disease. He discusses the role of glucose and glutamine in cancer metabolism and emphasizes the potential of metabolic therapy, including ketogenic diets, for prevention and management. Explore the compelling intersection of biochemistry, lifestyle, and cancer with Seyfried's groundbreaking insights.Sponsors:ZocDoc: https://www.zocdoc.com/neuroHone Health Hormone Testing: https://honehealth.com/Momentous - Use code NEURO to get 20% off your order - https://www.livemomentous.com/neuro Timestamp 0:00 Challenging Cancer's Genetic Theory with Metabolic Insights4:54 Cancer as a Metabolic Disorder Not a Genetic Disease13:05 Challenging the Genetic Theory of Cancer Amidst Confirmation Bias15:27 Booking Doctor Appointments Easily with ZocDoc16:27 Mitochondria's Role in Cancer Cell Proliferation and Fermentation21:08 Mitochondrial Dysfunction and Its Role in Cancer Development31:23 Cancer Cells' Fermentation and Mitochondrial Dysfunction37:33 Metabolic Therapy as a Non-Toxic Cancer Treatment Alternative46:39 Exploring Diets and Metabolic Pressure on Cancer Cells49:36 Exercise and Diet in Cancer Treatment Targeting Glutamine50:50 Ketogenic Lifestyle's Impact on Cancer and Chronic Diseases52:40 Targeting Glucose and Glutamine to Combat Pancreatic Cancer54:36 Impact of Modern Lifestyle on Health and Chronic Diseases58:26 Metabolic Therapy as a Disruptive Cancer Prevention and TreatmentThe Neuro Athletics Newsletter Instagram: @louisanicola_Twitter : @louisanicola_YouTube: @Louisa NicolaThe Neuro Experience Podcast is proud to have hosted: Dr Andrew Huberman, Dr Gabrielle Lyon, Dr Layne Norton, Thomas DeLauer, Shawn Stevenson, Dr. Rocio Salas-Whalen, Saad Alam, Uma Naidoo, Dr. Lanna Cheuck, Angela Lee Pucci, Jillian Turecki, Dr. Jordan Feigenbaum, Dr. Darren Candow, Dr. Sue Varma, Evy Poumpouras, Dr Casey Means, Renee Deehan, Dr Chris Palmer, Dr Charles Brenner, Dr Joe Zundell, Dr Ray Dorsy, Dr Dale Bredeson, Dr. Ben Bikman
In this episode from 2011 I was joined by Paul Seyfried of Utah Shelter Systems to discuss civil defense in the US and in other nations, the continued threat of nuclear war, chemical attack and biological weapons. He also explains … Continue reading →
Could fighting off the most feared and deadly disease be as simple as controlling what you put on your plate? Here is the revolutionary cancer care advice you've never heard. Dr Thomas Seyfried is a Professor of biology, genetics, and biochemistry at Boston College. He has over 150 peer-reviewed publications and is also the author of books such as, ‘Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer'. In this conversation, Dr Thomas and Steven discuss topics such as, the link between blood sugar and cancer growth, how stress management impacts your cells, the biggest misconceptions about cancer, and how calorie restriction could prevent cancer. (00:00) Intro (01:59) What Would Dr Seyfried Say He Does? (02:37) How Much Of A Problem Is Cancer Globally? (04:30) What Types Of Cancer Are People Dying From? (05:02) How Many People Will Develop Cancer? (06:56) Where Does Cancer Rank In The Probabilities Of Taking My Life? (08:12) What Is The Fermentation Process? (12:16) How Have You Arrived At This Conclusion? (16:52) Why Do Cancers Grow So Rapidly? (19:17) What Are Ketones? (21:23) What Can We Learn About Cancer From Our Ancestors? (24:36) What Role Does Exercise Play In Fighting These Diseases? (25:44) What Lifestyle Choices Are Causing The Cancer To Develop? (29:07) Is Cancer Genetic? (31:09) How Do We Keep Our Mitochondria Healthy? (32:42) Is Cancer Genetic? (36:27) Why Haven't Opinions Changed Based On Dr Seyfried's Evidence? (38:27) If We Adopt This Mindset, What Will Happen To Cancer Statistics? (39:17) Are The Current Cures Working? (41:50) The Current Technologies Used To Prevent Cancer (49:10) How Do We Prevent Cancer? (51:06) Should I Be On A Keto Diet? (54:57) Dr Seyfried's Dog Study (57:14) Human Cases Of People That Have Followed Your Research (01:03:39) What Is Metabolic Therapy? (01:04:36) What Should Someone That Has Cancer And Is Listening To This Do? (01:07:52) Keto Plus Hyperbaric Oxygen Study (01:11:57) Can You Have A Pre-Disposition To Cancer? (01:12:28) Should I Restrict What I Eat, To Stave Off Cancer? (01:13:16) What's Your View On Fasting? (01:13:58) How Do I Get Into The Keto State? (01:17:10) Do We Need More Discipline? (01:18:36) What Happens When You Fast? (01:20:52) What Advice Would Dr Seyfried Give To His Kids? (01:22:14) Why Isn't Dr Seyfried Trying To Be Metabolically Perfect? (01:23:04) What Food Laws Would Dr Seyfried Introduce? (01:25:18) Is Dr Seyfried Hopeful? (01:28:14) And What If You Are Successful? (01:29:10) Are There Any Studies That Have Broken Dr Seyfried's Heart? (01:30:50) What Would Dr Seyfried Say To Someone Listening? (01:32:55) Guest's Last Question Follow Dr Thomas: Instagram - https://g2ul0.app.link/cwAePGF1pNb Twitter - https://g2ul0.app.link/0yuLM6I1pNb YouTube: You can purchase Dr Thomas' book, ‘Keto for Cancer: Ketogenic Metabolic Therapy as a Targeted Nutritional Strategy', here: https://g2ul0.app.link/1FotHad2pNb Spotify: You can purchase Dr Thomas' book, ‘Keto for Cancer: Ketogenic Metabolic Therapy as a Targeted Nutritional Strategy', here: https://g2ul0.app.link/1FotHad2pNb Watch the episodes on Youtube - https://g2ul0.app.link/DOACEpisodes My new book! 'The 33 Laws Of Business & Life' is out now - https://g2ul0.app.link/DOACBook You can purchase the The Diary Of A CEO Conversation Cards: Second Edition, here: https://g2ul0.app.link/f31dsUttKKb Follow me: https://g2ul0.app.link/gnGqL4IsKKb Sponsors: Shopify - http://shopify.com/bartlett Learn more about your ad choices. Visit megaphone.fm/adchoices
Today, I am blessed to have Dr. Thomas Seyfried here with me. Thomas N. Seyfried received his Ph.D. in Genetics and Biochemistry from the University of Illinois, Urbana, in 1976. He did his undergraduate work at the University of New England, where he recently received the distinguished Alumni Achievement Award. He also holds a Master's degree in Genetics from Illinois State University. Thomas Seyfried served with distinction in the United States Army's First Cavalry Division during the Vietnam War and received numerous medals and commendations. He was a Postdoctoral Fellow in the Department of Neurology at the Yale University School of Medicine and then served on the faculty as an Assistant Professor in Neurology. Dr. Seyfried argues that cancer is a metabolic disease, not a genetic one, and suggests that lifestyle factors play a role in its development. He highlights that if you wanted to get cancer, you would adopt a sedentary lifestyle, consume highly processed foods with long shelf lives, avoid fresh food, experience high levels of emotional stress, and deprive yourself of sleep. He notes that many people engage in these behaviors unknowingly, leading to increased rates of cancer, diabetes, obesity, and other chronic diseases. Seyfried's point is that to prevent cancer, individuals should focus on maintaining metabolic health through exercise, proper diet, stress management, and quality sleep. Dr. Seyfried highlights that the current medical understanding of cancer is rooted in the idea that it is a genetic disease, a concept taught in medical schools and upheld by oncologists. These professionals are trained to use traditional treatments like chemotherapy and radiation, focusing on managing toxicity rather than addressing the root cause. Seyfried argues that cancer is a metabolic disease driven by glucose and glutamine, but this crucial information is missing from training. He emphasizes the need for metabolic therapy, which targets the fuels cancer cells depend on while keeping healthy cells thriving, notably through ketosis. He expresses frustration at the medical community's resistance to acknowledging this approach despite mounting evidence that metabolic interventions could starve cancer cells and slow tumor growth. Tune in as Dr. Seyfried explains that while animals are hardwired to eat for survival, humans, with conscious awareness, can override this instinct, which can lead to disorders like anorexia. He highlights that modern diets, full of processed carbohydrates and fats, are far removed from what our ancestors ate, causing health issues like obesity, type 2 diabetes, and cancer. Additionally, he critiques the financial burden of cancer treatments, calling the system immoral, especially for the economically disadvantaged. Resources from this episode: Website: https://tomseyfried.com/ Cancer as a Metabolic Disease: https://www.amazon.com/Cancer-Metabolic-Disease-Management-Prevention/dp/0470584920/benazadi-20 Donate: https://www.bc.edu/bc-web/offices/alumni/giving.html