The set of life-sustaining chemical transformations within the cells of organisms
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What if the reason your health plan keeps failing is not a lack of discipline but a strategy never designed for your body? In this episode of Sharkpreneur, Seth Greene interviews Angelo Poli, Founder of MetPro and Author of MetPro: The Science to Transform, who explains why generic diets and standardized fitness advice often fail to deliver sustainable results. He explains how metabolic profiling uses individual data, ongoing feedback, and personalized adjustments to identify which nutrition and fitness strategies will produce the most progress. Angelo also reveals why busy entrepreneurs should rely less on willpower and instead build scientifically informed routines that yield the greatest results with the least wasted time. Key Takeaways:→ Every person responds differently to nutrition and exercise. → Metabolic profiling assesses a person's starting point and identifies the specific adjustments needed to improve body composition, energy, and performance. → A perceived “slow metabolism” may be influenced by how the body has adapted to a person's long-term habits. → Busy entrepreneurs are often derailed when their schedules become overwhelming, making a reliable routine more valuable than temporary motivation.→ The most effective health strategy focuses on actions that deliver the greatest return without unnecessary effort. Angelo Poli is the founder of MetPro and the author of MetPro: The Science to Transform. For more than 20 years, he's helped entrepreneurs, executives, professional athletes, and high performers optimize energy, body composition, performance, and longevity. His work centers on a simple idea: performance isn't just about training harder. It's about understanding how your metabolism adapts to stress, recovery, fueling, and workload over time. That's why strategies that work at one stage of training often stop working at the next. After a serious injury left him walking with a cane for nearly a decade, Angelo became obsessed with understanding what truly drives lasting transformation. That pursuit ultimately led to the creation of MetPro and a methodology that has helped more than 20,000 people achieve sustainable results. Connect With Angelo:Website: https://metpro.co/Facebook: https://www.facebook.com/MetabolicProfiling/Instagram: https://www.instagram.com/metproco/YouTube: https://www.youtube.com/@metabolicprofiling
Text us a comment or question!If you're over 50 and you've ever said - or even thought - "My metabolism is broken," this episode is for you.This week, I'm continuing my special Behind the Book series by reading Chapter 4 of my upcoming book: Fully Alive: A Blueprint for Building the Strongest, Healthiest, and Most Meaningful Second Half of Your Life.And in this chapter, we're tackling one of the biggest - and most discouraging - beliefs in the over-50 health and fitness world - that aging has somehow broken your metabolism.Because let's face it… it can certainly feel that way.You eat less. You exercise more. You try harder. And somehow the strategies that worked at 30 or 40 don't seem to work anymore.So what happened?In this chapter, I'll explain why your metabolism isn't some mysterious force conspiring against you - and why "broken" may be completely the wrong way to think about what's happening inside your body.Instead, we'll explore a much more powerful idea - Adaptation.Your body is constantly responding to the environment you create and the signals you send it.Years of restrictive dieting. Loss of muscle. Reduced activity. Poor sleep. Stress. Repeated cycles of losing and regaining weight. Your body notices all of it - and adapts accordingly.But here's the incredibly good news - adaptation works both ways.The same body that adapted to years of restriction and inactivity can begin adapting to strength training, better nutrition, movement, recovery, and consistency.Your body isn't finished at 50. Or 60. Or 70.It's still listening.In This Episode, You'll Learn:What metabolism actually is—and what it isn'tWhy having a "slow metabolism" is more complicated than most people realizeWhy weight loss can become more difficult even when you're eating lessHow years of dieting can change the environment your body is responding toWhy muscle loss and declining activity matter so much after 50The difference between metabolic damage and metabolic adaptationWhy the bathroom scale can convince you nothing is working—even when your health is improvingWhy trying to force your body to lose weight may be the wrong approachHow strength training, movement, nutrition, recovery, and consistency send your body new signalsWhy your goal isn't to get your 25-year-old metabolism backAnd why the body you have today may be far more capable of change than you've been led to believe The big takeaway?Stop asking "Is my metabolism broken?"Start asking "What has my metabolism been responding to?"Because once you stop treating your body like the enemy, you can begin creating an environment that encourages it to thrive.And that's where things get exciting.
Today we are doing something we have never done before.Once a month, members of The Metabolic Initiative get an hour to put their own questions directly to the scientists and clinicians at the forefront of metabolic health. Those sessions stay inside the platform. This one does not.After Dr. Ben Bikman joined us for episode 100, the questions kept coming. So we invited him back to sit with Dr. Dominic D'Agostino and MHI co-founder Victoria Field for a live member Q&A, and for the first time we are releasing the full session publicly.What came out of it: GLP-1 medications and the muscle loss debate, and how Ben's own position on these drugs has shifted. Insulin resistance and ceramides. Exogenous ketones, and when they may actually be useful. Metabolic approaches to cancer and the glucose ketone index. Exercise timing. Type 1 diabetes. Cortisol and fat distribution. Supplements.Questions Answered in This Episode:The muscle loss debate around GLP-1s has become polarized. Should clinicians be worried about muscle loss, muscle function, or neither?If you were diagnosed with cancer, are there any metabolic therapies you would start immediately?How long can it take for ceramides in adipose tissue to resolve — and insulin resistance to improve?Bioidentical D-BHB exogenous ketones are substantially more expensive. What is the value proposition over other forms?GLP-1 receptor agonists consistently raise resting heart rate. Is that something to be concerned about?Are there any emerging approaches to improving the management of type 1 diabetes?What happens metabolically, and to fat cells, glucose and ketones, when taking corticosteroids?This is the kind of conversation we host every month inside The Metabolic Initiative, alongside expert presentations from our conferences and a library built entirely around metabolic health and therapy, with CME credit available on eligible content for healthcare providers.If you want to be in the room for the next one, the first seven days are free. membership.metabolicinitiative.comSpecial thanks to the sponsors of this episode:Genova Connect: Get 15% off any Genova Connect test kit with code METABOLICLINK here.Cowboy Colostrum: Get up to 25% off with code METABOLIC here.More LinksDr. Ben Bikman's website: benbikman.comInsulin IQ: insuliniq.comYouTube: youtube.com/@benbikmanInstagram: @benbikmanphdIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: InstagramFacebookYouTubeLinkedInPlease keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
Thabo Shole Mashao speaks to Nathalie Mat, Registered Dietitian discussing what metabolism is and metabolic processes. They also touch on how different diets affect our metabolic processes. The Clement Manyathela Show is broadcast on 702, a Johannesburg based talk radio station, weekdays from 09:00 to 12:00 (SA Time). Clement Manyathela starts his show each weekday on 702 at 9 am taking your calls and voice notes on his Open Line. In the second hour of his show, he unpacks, explains, and makes sense of the news of the day. Clement has several features in his third hour from 11 am that provide you with information to help and guide you through your daily life. As your morning friend, he tackles the serious as well as the light-hearted, on your behalf. Thank you for listening to a podcast from The Clement Manyathela Show. Listen live on Primedia+ weekdays from 09:00 and 12:00 (SA Time) to The Clement Manyathela Show broadcast on 702 https://buff.ly/gk3y0Kj For more from the show go to https://buff.ly/XijPLtJ or find all the catch-up podcasts here https://buff.ly/p0gWuPE Subscribe to the 702 Daily and Weekly Newsletters https://buff.ly/v5mfetc Follow us on social media: 702 on Facebook https://www.facebook.com/TalkRadio702 702 on TikTok https://www.tiktok.com/@talkradio702 702 on Instagram: https://www.instagram.com/talkradio702/ 702 on X: https://x.com/Radio702 702 on YouTube: https://www.youtube.com/@radio702 See omnystudio.com/listener for privacy information.
View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this "Ask Me Anything" (AMA) episode, Peter takes a deep dive into the liver and its central role in metabolic health. He explains why the liver can serve as a "canary in the coal mine" for metabolic dysfunction and explores how insulin resistance, visceral fat, alcohol consumption, genetics, and hormones contribute to liver disease, along with how increasing muscle mass can benefit liver health. Peter provides a framework for understanding the progression of liver disease, highlighting which stages are reversible and why early detection matters. He explains why normal liver enzymes can provide false reassurance, which labs he uses to assess liver health, and the tools available for detecting fibrosis and more advanced disease. Peter then breaks down the interventions that can meaningfully improve liver health once risk or disease is identified, ranging from diet and exercise to GLP-1–based therapies and other medications. Finally, he examines popular claims around liver "detoxification" and supplements, separating what is supported by evidence from what is unlikely to meaningfully improve liver health. If you're not a subscriber and are listening on a podcast player, you'll only be able to hear a preview of the AMA. If you're a subscriber, you can now listen to this full episode on your private RSS feed or our website at the AMA #88 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here. We discuss: Why the liver is the "canary in the coal mine" for metabolic dysfunction, and an overview of what the liver does [2:00]; The relationship between the liver and blood sugar control [6:30]; A framework for understanding how metabolic disease affects the liver [9:15]; Chronic caloric surplus and insulin resistance as drivers of liver disease [11:00]; Liver diseases that result from metabolic dysfunction and the difference between steatosis and fibrosis [15:15]; How visceral fat affects liver health [20:00]; The importance of lifestyle interventions for liver and metabolic health: resistance training, not drinking calories, and the impact of fructose [22:00]; Why alcohol-associated liver disease is more common than we give it credit for [26:30]; Genetic and hormonal risks for liver disease [31:45]; Labs that objectively measure liver health and the FIB-4 score [35:30]; FibroScan: non-invasive imaging of the liver [44:30]; The resiliency of the liver: an organ that can heal itself [47:00]; Fibrosis staging and its impact on mortality and cancer risk [49:15]; Interventions for someone with MASLD: weight loss and GLP-1s [52:00]; Other medications used to treat metabolic liver disease [57:00]; The role of exercise in treating metabolic liver disease: caloric deficit and building muscle [59:45]; The myth of liver detoxes and cleanses, and a few supplements that may benefit the liver [1:01:15]; A practical summary: how to assess your risk and the levers that reverse the disease [1:08:00]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube
In this episode, Dr. C. Joe Northup, MD, FACS, FASMBS, Bariatric Surgeon & 40th President of the American Society for Metabolic and Bariatric Surgery (ASMBS), discusses the impact of GLP-1 medications on bariatric surgery, the durability and safety of surgical treatment, and expanding access to obesity care. He also shares leadership lessons, the future of metabolic care, and why obesity should be treated as a disease rather than a character flaw.
MAPS BOGO: https://mapsbogo.com Buy one get one free — mix and match any of the top 10 most popular programs (Anabolic, Aesthetic, Performance, 15 Minutes, Anywhere, Symmetry, Starter, Muscle Mommy, Powerlift, 40+) for $157. In this episode the guys break down why being fat and fit is objectively better than being skinny and unfit across every major health metric — longevity data, energy levels, pain and injury risk, and hormone health. They cover the research showing fit overweight individuals have similar or better mortality outcomes than normal weight but unfit people, why frailty is actually one of the highest risk categories in medicine, and why the look people chase by restricting often leads to worse health and worse aesthetics. They also get into Hadi Choopan's legendary pyramid squat session on the Smith machine working up to 500 pounds and back down, Rho Nutrition's liposomal creatine solving the digestion issue for people who can't handle regular creatine, Procter and Gamble acquiring Thorne and what it signals about where the wellness industry is heading, Philip Morris buying food companies in the 1970s and applying their addiction science to processed food, Crisp Power protein pretzels and why the combination of high protein and fiber produces unusual satiety, an Anthropic study where scientists planted a thought in Claude's neural network and it became aware something was wrong, and Myspace relaunching with a no-algorithm model led by the brothers who say they originally conceived the idea behind Facebook. Then they answer questions submitted through Instagram. SPONSORS Crisp Power (protein pretzels): https://www.crisppower.com/mindpump Code: MINDPUMP for 10% off. 28g protein per bag, high fiber, zero added sugar, vegan. Rho Nutrition (liposomal creatine, NAD+ and Glutathione): https://www.rhonutrition.com/discount/MINDPUMP Code: MINDPUMP for 20% off everything. Paleo Valley (grass-fed fermented meat sticks): https://paleovalley.com/mindpump 15% off automatically applied at checkout, no code needed. LINKS Mind Pump Store: https://mindpumpstore.com Maps Fitness Products: https://mapsfitnessproducts.com Instagram: @mindpumpmedia 0:00 - Intro 1:54 - Being fat and fit is better than being skinny and unfit — the data breakdown 5:18 - Why frailty is one of the highest risk categories in all of medicine 11:55 - Metabolic flexibility, muscle as storage and why fitness is the real multiplier 19:42 - Does looking better actually make you happier? What the data says 27:10 - Hadi Choopan's legendary pyramid squat session — 500 pounds on the Smith machine 33:18 - Greatest gym feats — the guys share their own legendary training moments 39:40 - Rho liposomal creatine — solving the digestion problem for people who can't handle regular creatine 41:32 - Procter and Gamble acquires Thorne — what it signals about the wellness industry 45:23 - Philip Morris bought food companies in the 1970s and applied their addiction science to processed food 53:34 - Crisp Power protein pretzels — why the protein and fiber combination creates unusual satiety 55:03 - Claude's neural network study — AI became aware something was planted inside it 1:01:35 - Myspace is relaunching with no algorithms — and the founders' connection to the Facebook story 1:04:36 - Q&A: What AB exercises are actually worth doing? 1:07:39 - Q&A: If muscle memory is real, why not do an aggressive cut and regain muscle after? 1:09:47 - Q&A: How to bulletproof the QL and lower back 1:11:10 - Q&A: Should you eat before a 5am workout?
Send us Fan MailToday we're releasing a new episode from a brand new series called the Boundless Body Radio Heritage Series! I wanted to do something extra special to celebrate 1,000 podcast episodes recorded here at Boundless Body Radio, a milestone that we hit on June 24, 2026!These episodes are actually not new, although they might be new to you! When we first got started back in October, 2020, I was so fortunate that so many incredible people said "YES" to being hosted on the show, however, we didn't have very many listeners at the time!Today, we get thousands of downloads every single month, and are usually included in the top 150 Fitness and Nutrition Podcasts on the Apple Podcast charts!To honor our amazing guests, I will be selecting one of those original episodes and posting them here on for this special series!As I was going through these episodes again, I remembered how valuable these conversations actually were. it was really striking how much the information these experts have shared has born out to be even more accurate several years later.The audio quality of a show was not as good back then as it is now, but I still really hope you enjoy these episodes, and find them relevant and helpful to you today!Cheers, thanks as always for listening, and I really hope you enjoy this episode of the Boundless Body Radio Heritage Series!Dr. Thomas Seyfried is a returning guest on our show! Be sure to check out his first appearance on Boundless Body Radio on episode 60, which one of the most fascinating discussions we've ever had, all about cancer as a metabolic disease! He was also hosted on episode 363 of our podcast.Thomas N. Seyfried received his Ph.D. in Genetics and Biochemistry from the University of Illinois, Urbana, in 1976. He was a Postdoctoral Fellow in the Department of Neurology at the Yale University School of Medicine and then served on the faculty as an Assistant Professor in Neurology. Other awards and honors have come from such diverse organizations as the American Oil Chemists Society, the National Institutes of Health, The American Society for Neurochemistry, the Ketogenic Diet Special Interest Group of the American Epilepsy Society, the Academy of Comprehensive and Complementary Medicine, and the American College of Nutrition.Dr. Seyfried has over 150 peer-reviewed publications and is the author of the book, Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer (Wiley, 1st ed., 2012).Find Dr. Seyfried at-https://foundationformetaboliccancertherapies.com/Movie, coming soon- CANCERREVOLUTION: A Cancer Science Documentary with Dr. Seyfried and former podcast guest Travis Christofferson.Find Boundless Body at-myboundlessbody.comFind Boundless Body at-myboundlessbody.comBook a session with us here!
What's the difference between lymphedema and ordinary leg swelling? Discover the underlying causes of lymphedema, the connection between lymphedema and diet, and how supporting your metabolic health may help reduce chronic leg swelling and lymphedema symptoms.0:00 Lymphedema diet connection 0:12 Lymphatic drainage explained 1:08 Edema vs. lymphedema1:59 The lymphatic system 2:48 Lymphedema causes5:30 Lymphedema and metabolic health7:05 Strength training for lymphedema7:43 More lymphedema solutions
GLP-1 receptor agonists have transformed weight loss and metabolic health—but what are we overlooking? In this episode of New Frontiers in Functional Medicine, Dr. Kara Fitzgerald is joined by Dr. Sanjay Bhojraj and Dr. Alexis Gonzales to explore the clinical tradeoffs of GLP-1 therapy, including lean muscle preservation, nutrient status, weight regain, and long-term metabolic health. The conversation also examines SiPore, an engineered silica-based intervention that works locally in the GI tract to slow the breakdown and absorption of carbohydrates and fats. Dr. Fitzgerald and her guests discuss findings from the randomized, double-blind, placebo-controlled SHINE trial, including outcomes related to A1c, visceral fat, waist circumference, cholesterol, and lean mass. They also explore how CGMs can reveal post-meal glucose patterns, why muscle preservation matters during weight loss, and how clinicians can support patients transitioning off GLP-1 medications—including those preparing for pregnancy, IVF, or surgery. Full show notes + references: https://www.drkarafitzgerald.com/fxmed-podcast/ GUEST DETAILS Sanjay Bhojraj, MD, FACC is an interventional cardiologist and Fellow of the American Academy of Anti-Aging Medicine specializing in cardiometabolic health, longevity medicine, and precision cardiovascular prevention. He's the founder of the Laguna Institute of Functional Medicine. His programs focus on reversing metabolic dysfunction, improving resilience, and reducing cardiovascular risk through lifestyle optimization and advanced diagnostic testing. Dr. Alexis Gonzales ("Dr. G") is OvationLab's Senior Clinical Implementation and AI Specialist, translating breakthrough research into practical clinical workflows, and holds advanced degrees in biochemistry (Saint Mary's), biotechnology (Johns Hopkins), and naturopathic medicine (Bastyr). She provides concierge functional-medicine care at her private practice in California—focusing on endometriosis, fertility, PCOS, and menopause—while distilling emerging research into practical frameworks at conferences to make integrative solutions accessible. http://sigridpro.com/DRKF THANK YOU TO OUR SPONSOR SIGRID http://sigridpro.com/DRKF *CONNECT with DrKF* Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You Practitioner Training Program: https://www.drkarafitzgerald.com/trainingyyi/ Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw
Our dear friends invited us to an event this weekend in LA… they are partnering with Gary Brecka to build Ultimate Longevity Centers which will bring treatments and testing that just hasn't been easily accessible before now. I believe the way we look at aging is outdated and I'm going to share the biggest take aways I got from his on stage message and chatting with him one on one. We are talking about very practical starting points and Gary Brecka's actual morning health routine. Stop waiting until something is wrong to start taking care of your body. We have been taught this idea that getting older automatically means getting weaker, having less energy, gaining weight, losing muscle, sleeping worse, becoming more anxious, needing more medications and eventually developing all of the diseases that "run in our family." Gary challenges a lot of that thinking. His message is essentially… What if we became obsessed with keeping our bodies functioning incredibly well for as long as possible? What if instead of asking, "How do I treat disease once I have it?" we asked, "How do I create a body that is incredibly difficult for disease to thrive in?" And then there's the longevity piece that completely fascinates me. Gary believes we're entering a period where medicine, AI, biological data and longevity research are going to advance so rapidly that lifespan could look radically different in the future. Maybe 120. Maybe beyond. We don't know. But what we do know is that we need to keep ourselves healthy enough NOW to benefit from whatever becomes possible later. So today's episode is about doing the things that give you the strongest, healthiest, most capable body possible. I've been listening to Gary Brecka talk about health, longevity, anxiety, genetics, sleep, sunlight, oxygen, muscle, bloodwork and what he believes is coming next in longevity science. THE BIG IDEA: YOUR HEALTH IS BUILT EVERY DAY One of my biggest takeaways from Gary is that health isn't something we deal with when there's a problem. It's something we're building every single day. Your sleep last night matters. What you do when you wake up matters. Whether you move your body matters. Whether you maintain muscle matters. Your metabolic health matters. Your stress matters. Your relationships matter. Your nutrition matters. Your environment matters. And individually, none of these things feels life-changing. But repeated for years and decades… they become your life. Gary describes his routine as simple, portable and repeatable. I LOVE that. Because the best health routine isn't the $100,000 biohacking setup. It's the one you'll actually do every day. HABIT #1: HYDRATE BEFORE YOU DO ANYTHING ELSE Gary starts his morning with water and minerals. One version of his routine is a large glass of room-temperature water with mineral salt and sometimes lemon. His current routine also frequently includes mineral salt, hydrogen water and essential amino acids. Wake up and hydrate. You've just spent roughly eight hours without drinking anything. Don't make coffee your first liquid of the day. Put water next to your bathroom sink. Put it next to your coffee machine. Make it automatic. Gary likes mineral salt because sodium and other minerals participate in fluid balance and normal nerve and muscle function. HABIT #2: GET OUTSIDE FIRST THING Gary says to get outside within the first part of your morning and get natural outdoor light into your eyes. His routine generally calls for about 10 minutes outside. Morning light helps tell your brain: It's daytime. Start the clock. Light is one of the strongest environmental signals for the circadian system. Properly timed morning light can shift circadian timing earlier and increase daytime alertness. And I love thinking of sleep this way: Your good night's sleep starts in the morning. We tend to think sleep health starts when we crawl into bed. But your body has been receiving signals all day telling it when to be awake and when to prepare for sleep. HABIT #3: BREATHE ON PURPOSE Gary talks about oxygen constantly. His personal morning practice has included three rounds of deep breathing followed by breath holds. And this connects to another thing we've been talking about: Anxiety. I love the idea that when you feel anxious, you shouldn't immediately decide: "I'm an anxious person." Anxiety is a state your nervous system is experiencing. Sometimes your thoughts are driving your physiology. And sometimes your physiology can amplify anxious thoughts. Either way, changing the physical state can sometimes help change the mental state. Research on structured breathwork has found modest improvements in stress and anxiety, although it isn't a cure-all and the quality of studies varies. HABIT #4: GIVE YOUR BRAIN SILENCE Gary often combines his morning breathing with quiet, gratitude and reflection. He has described sitting quietly for around 10 minutes, looking toward the horizon or closing his eyes and thinking about gratitude. (PodScripts (https://podscripts.co/podcasts/the-ultimate-human-with-gary-brecka/246-gary-brecka-answers-googles-most-searched-questions-on-his-diet-wellness-and-lifestyle?utm_source=chatgpt.com)) Think about how different this is from what most of us do. Eyes open. Phone. Email. Instagram. News. Text messages. Stress. Other people's priorities. And we wonder why we feel overstimulated. TRY THIS: Before consuming everybody else's thoughts… Have some of your own. What am I grateful for? What matters today? Who needs me today? How do I want to feel today? What is actually important? PRACTICAL VERSION: Five minutes. That's it. No phone. No podcast. No input. Just quiet. HABIT #5: USE CONTROLLED DISCOMFORT Cold exposure is another major Brecka habit. If he has access to a cold plunge, he uses it. When traveling, he has said a cold shower works too. But I think there is a bigger lesson here than whether everybody needs to buy a cold plunge. Stop designing your entire life around comfort. Human beings are unbelievably adaptable. Exercise is stress. Heat is stress. Cold is stress. Fasting is stress. Challenging your brain is stress. The key is appropriate amounts of stress followed by recovery. HABIT #6: MOVE EARLY Gary includes movement in his morning routine. But here's what I love: It doesn't need to be a full workout. Walk. Stretch. Squat. Lift. Do yoga. Go outside. Movement tells your body: We're alive. We're using this machine today. And then keep moving after the morning is over. One exceptionally practical habit is walking after meals. Instead of finishing dinner and immediately sitting on the couch… WALK FOR 10 MINUTES. Moving skeletal muscle after eating can help the body handle glucose. You don't need workout clothes. You don't need a gym. You don't even need to sweat. Walk around your neighborhood. Walk your dog. Walk while you're on a phone call. ONE OF THE EASIEST HEALTH RULES: Eat → walk. HABIT #7: BUILD MUSCLE LIKE YOUR FUTURE DEPENDS ON IT This is where I think longevity conversations get really practical. MUSCLE IS NOT JUST ABOUT LOOKING GOOD. Maintaining muscle becomes increasingly important as we age. Resistance training is one of the most powerful non-drug strategies available for preserving and building skeletal muscle. Losing muscle eventually affects: strength balance mobility independence your ability to recover from illness your ability to do normal life You're not building your 2026 body. You're building your 2056 body. HABIT #8: PRIORITIZE PROTEIN AND REAL FOOD- avoid processed foods Gary emphasizes protein and essential amino acids because preserving lean tissue is a major part of his longevity philosophy. The research strongly supports resistance training for preserving muscle, while evidence regarding how much additional benefit comes from protein supplementation specifically is more mixed. HABIT #9: PROTECT YOUR METABOLIC HEALTH I think this deserves WAY more attention. We obsess over weight. Gary talks much more about metabolic health. There is a difference. Weight is one number. Metabolic health includes things like: blood glucose insulin sensitivity blood pressure blood lipids waist circumference fitness body composition Instead of only asking: "How much do I weigh?" Ask: "How well is my body functioning?" Someone can lose weight while losing muscle. Someone can be thin and still have poor metabolic health. PRACTICAL HABITS: Strength train. Walk. Walk after meals. Eat mostly whole foods. Get enough sleep. Maintain healthy body composition. Reduce constant snacking if it isn't serving you. Know your basic health numbers. THE GOAL ISN'T SKINNY. The goal is metabolically capable. HABIT #10: TEST… DON'T JUST GUESS This might be one of my favorite parts of Brecka's philosophy. Stop guessing about everything. If you're exhausted all the time… investigate. If you're unusually anxious… investigate. If your sleep has suddenly changed… investigate. If your energy has disappeared… investigate. If your hormones feel completely different… investigate. If you feel awful despite doing "everything right"… investigate. Don't immediately decide: "I'm getting old." "This runs in my family." "I'm just an anxious person." "My metabolism sucks." "This is just how I am." ASK BETTER QUESTIONS. Could something modifiable be contributing? sleep nutrient deficiencies thyroid function iron status medications hormones metabolic health stress alcohol caffeine environment psychological health This does NOT mean ordering every exotic test on the internet. It means becoming curious about your own biology. HABIT #11: DON'T TURN ANXIETY INTO YOUR IDENTITY This is worth repeating because I think this is such an important mental shift. Instead of: "I AM anxious." Try: "I'm experiencing anxiety." Those are very different statements. One is an identity. One is a temporary condition worth investigating. Gary's message leans heavily toward investigating biology. He talks about things like methylation pathways and MTHFR. There are legitimate genetic influences on anxiety. But anxiety is complex. Research suggests anxiety disorders arise through a combination of genetic vulnerability and environmental influences, not one single "anxiety gene." (PubMed (https://pubmed.ncbi.nlm.nih.gov/15699295/?utm_source=chatgpt.com)) So I would approach it from ALL DIRECTIONS: Calm the body. Investigate the biology. Work on the thoughts. Breathwork. Sleep. Exercise. Less overstimulation. Healthy relationships. Therapy when needed. Medical evaluation when something feels physiologically off. Nutrition. Less caffeine when appropriate. Time outdoors. Don't choose between: "It's psychological." or "It's biological." It can be both. HABIT #12: GENETICS ARE INFORMATION… NOT ALWAYS DESTINY This is another Gary Brecka concept that I think is incredibly empowering when we phrase it accurately. People say: "Diabetes runs in my family." "Anxiety runs in my family." "Heart disease runs in my family." "Autoimmune disease runs in my family." And we can start thinking: Well… I guess that's coming for me too. But genetics often represent susceptibility rather than certainty. Your genes can increase risk. Your environment can increase or decrease risk. Your behaviors matter. Your metabolic health matters. Your exposures matter. Your entire biological environment matters. So instead of thinking: "My family gets this disease." Think: "I may have inherited a vulnerability. What parts of that vulnerability can I modify?" THAT is empowering. Important distinction: Some diseases absolutely are caused by inherited genetic mutations. So we should not say: "Genetic diseases aren't real." They absolutely are. The better message is: Genes can load the gun. They don't always pull the trigger. And with many complex chronic diseases, what ultimately happens involves an interaction between genetics and environment. HABIT #13: STOP THINKING OF SLEEP AS LOST PRODUCTIVITY Sleep is when your body gets to repair. And Brecka's evening routine reflects this. He emphasizes regular sleep, reducing stimulation late at night and setting up the next morning by protecting the night before. My favorite way to think about sleep: Tomorrow starts tonight. Stop trying to squeeze another hour out of your day if it destroys tomorrow. Decide when you're going to bed BEFORE you're tired. Dim things down. Get off your phone. Stop working. Let the nervous system receive a signal that the day is ending. Pick a bedtime and protect it the same way you'd protect an important meeting. NOW LET'S TALK ABOUT LIVING TO 120 The speed of advancement is changing. AI can analyze enormous amounts of biological data. Diagnostics are improving. Scientists are studying the actual biology of aging rather than treating aging purely as an unavoidable decline. Researchers are investigating cellular senescence, epigenetics, regenerative medicine and other mechanisms associated with biological aging. Gary believes these developments could eventually change human lifespan dramatically. And his argument is essentially: Stay alive and stay healthy long enough to benefit from what's coming. That hit me HARD. Because imagine being 75 in the future… But instead of arriving at 75: metabolically sick weak frail sedentary cognitively struggling carrying multiple preventable chronic illnesses You arrive: strong metabolically healthy active engaged cognitively sharp sleeping well maintaining muscle surrounded by people you love THAT is the bridge. Not: "How do I live forever today?" But: "How healthy can I be when tomorrow's medicine arrives?" DON'T JUST CHASE LIFESPAN. CHASE HEALTHSPAN. I don't want to simply exist until I'm 120. I want to LIVE. I want to: travel walk everywhere lift my suitcase play with grandchildren hike swim think clearly learn new things have great conversations have energy be independent laugh have purpose wake up excited THAT is longevity. Not adding years at the end where you can't live. Adding life to the years. WHAT SHOULD WE ACTUALLY DO RIGHT NOW? If you took this entire episode and boiled it down into a daily longevity checklist… MORNING Hydrate. Get outside. Get natural morning light. Breathe intentionally. Spend a few minutes in quiet. Think about gratitude. Move your body. Use cold exposure if you enjoy it and it's appropriate for you. Don't immediately flood your brain with stress. DURING THE DAY Eat nutrient-dense real food. Prioritize protein. Strength train consistently. Walk. Walk after meals. Stay metabolically healthy. Maintain muscle. Build meaningful relationships. Have purpose. Keep learning. Get outside. NIGHT Stop eating mindlessly late into the evening. Reduce stimulation. Get off the phone. Give yourself a predictable bedtime. Sleep. THROUGHOUT YOUR LIFE Know your numbers. Do appropriate preventive screening. Investigate symptoms rather than ignoring them. Don't automatically assume something is "just aging." Don't automatically assume family history means destiny. Continue learning as science changes. Protect your muscle. Protect your metabolism. Protect your brain. Protect your relationships. Protect your sleep. THE SIMPLEST VERSION OF EVERYTHING GARY BRECKA IS SAYING 1. Get sunlight. 2. Breathe. 3. Hydrate. 4. Move. 5. Build muscle. 6. Eat real nutrient-dense food. 7. Protect your metabolism. 8. Sleep like it matters. 9. Challenge your body sometimes. 10. Investigate problems instead of simply accepting them. 11. Don't confuse genetic risk with guaranteed destiny. 12. Don't turn anxiety into your identity. 13. Build relationships and a life that gives you purpose. 14. Stay unbelievably healthy while longevity science continues advancing. And maybe most importantly… DON'T WAIT UNTIL YOU'RE SICK TO BECOME INTERESTED IN YOUR HEALTH. I learned that every single thing that gives me the best chance of being healthy at 120 also gives me a better life at 45. Getting sunlight tomorrow morning makes tomorrow better. Sleeping tonight makes tomorrow better. Building muscle makes this decade better. Eating well makes today better. Getting outside makes today better. Putting my phone down makes today better. Managing anxiety makes today better. Having people I love around me makes today better. So this isn't really an episode about trying to cheat death. It's about refusing to sleepwalk through your health. Your body is the vehicle that carries you through every single experience you're hoping to have. Every trip. Every adventure. Every business idea. Every dinner. Every workout. Every moment with your kids. Every future grandkid. Everything. So take ridiculously good care of it. And instead of looking at aging and thinking… "Well, I guess everything starts going downhill from here…" What if we thought completely differently? What if our goal was: I want to be stronger next year. Healthier next year. More metabolically healthy next year. More informed next year. More capable next year. And then do it again. And again. And again. For decades. Let's make the goal to be fully alive for as much of it as humanly possible. That's the health lesson I'm taking from Gary Brecka. Don't wait for the future of longevity medicine. Build the kind of body today that's ready for it.
Metabolic health is far more nuanced than conventional nutrition advice suggests. On this week's episode of the WHOOP Podcast, WHOOP Global Head of Human Performance and Principal Scientist Dr. Kristen Holmes sits down with Metabolic Health Expert Dr. Nick Norwitz MD PhD to discuss why curiosity is one of the most powerful tools for improving long-term health. Dr. Nick Norwitz shares how a ketogenic diet unexpectedly put his inflammatory bowel disease into remission after numerous conventional treatments had failed. This experimentation sparked a career dedicated to challenging assumptions with rigorous science and thoughtful self-experimentation. Together, Dr. Nick Norwitz and Dr. Kristen Holmes unpack the difference between "evidence-based" and truly individualized care. This episode continues to explore why muscle, sleep, and visceral fat play central roles in brain, heart, and metabolic health. From discussions on protein, the microbiome, and emerging therapies to Nick's famous Oreo-versus-statin experiment, the conversation encourages listeners to move beyond one-size-fits-all health advice, and partner with their healthcare providers to embrace safe, data-informed experimentation for a better understanding of their biology. Shownotes:(00:00) Trailer Intro(00:43) Who Is Dr. Nick Norwitz?(03:07) Nick's Personal Health Journey(08:29) Nutrition as a Medical Intervention(12:41) What Does “Evidence-Based” Care Really Mean?(16:42) The Key to Optimizing Your Health(19:17) Debunking Metabolic Health Myths(20:46) The Benefits of Training and Exercise(26:29) How Metabolism Affects Strength, Cardio, and Brain Health(30:03) How Does Sleep Impact Inflammation?(32:35) GLP-1s and Your Metabolism: What's Really Happening?(34:47) Nick's Take on Self-Experimentation(35:43) The Oreo vs. Statin Study(45:19) How to Burn Fat(49:43) Do We Really Need to Focus on Protein?(51:25) What Is Visceral Fat—and How Do You Lose It?(56:08) Why You Should Stay Curious About Your HealthResources:Fitness and aging (Nature Aging 2026); https://www.nature.com/articles/s43587-026-01150-x Visceral fat and resistant starch: (Nature Metabolism 2024): https://www.nature.com/articles/s42255-024-00988-y Visceral fat and resistant starch, **YouTube Breakdown: https://youtu.be/wnEApLnKDRI Visceral fat and brain volume: (Nature Comm 2026): https://www.nature.com/articles/s41467-026-71141-4 Leg power and longevity (twin study): https://pubmed.ncbi.nlm.nih.gov/26551663/ 600-calorie exercise burn study (Nature Metabolism 2025): https://www.nature.com/articles/s42255-025-01236-7 Microbiome and beige fat study (Nature 2026): https://www.nature.com/articles/s41586-026-10205-3 Oreo versus statin study: https://pubmed.ncbi.nlm.nih.gov/38276308/Follow Nick Norwitz:WebsiteYouTubeInstagramXLinkedInSubstackSupport the showFollow WHOOP:Sign up for WHOOP Advanced LabsTrial WHOOP for Freewww.whoop.comInstagramTikTokYouTubeXFacebookLinkedInFollow Will Ahmed:InstagramXLinkedInFollow Kristen Holmes:InstagramLinkedInFollow Emily Capodilupo:LinkedIn
HEALTH NEWS Chamomile Rinse Matches Chlorhexidine in Reducing Plaque and Gum Inflammation, Trial Finds A few minutes of sprinting could make a bigger impact than 90 minutes of moderate running Ultra-processed foods linked to higher prostate cancer risk in men Cinnamon Supplementation Associated With Lower Blood Sugar and Cholesterol in Review of 21 Meta-Analyses Healthy lifestyle cuts hearing impairment risk by 14%, metabolism is key driver Chamomile Rinse Matches Chlorhexidine in Reducing Plaque and Gum Inflammation, Trial Finds Western University of Arad (Romania), August 12 2026 (Natural News) A chamomile herbal rinse reduced plaque buildup and gum inflammation on par with chlorhexidine. Researchers enrolled 175 healthy adults and divided them into five groups: chamomile, sage, ginger, placebo, or chlorhexidine rinses, the report stated. Over twelve weeks, researchers tracked plaque accumulation and gingival inflammation using standardized dental indexes. Participants rinsed daily with their assigned solution, and measurements were recorded at intervals across the study period. Chamomile's effect relies on plant compounds including apigenin and chamazulene, which act through anti-inflammatory pathways, while chlorhexidine works through strong antimicrobial action, researchers said. Chamomile flower material contains acylated derivatives of apigenin 7-O-glucoside. Every active rinse, including chamomile, produced significant reductions compared to placebo. Chamomile performed statistically on par with chlorhexidine, the rinse most dentists reach for first. Chlorhexidine is a prescription-strength antiseptic that dentists consider the gold standard for controlling plaque. Long-term chlorhexidine use commonly causes tooth staining, taste changes, and irritation of soft tissue inside the mouth. A few minutes of sprinting could make a bigger impact than 90 minutes of moderate running Rockefeller University, August 13 2026 (Eurekalert) Three minutes of sprinting can do something that 90 minutes of moderate exercise apparently cannot: dramatically reshape the molecular contents of the bloodstream. Rockefeller researchers comparing different intensities of exercise found that six sets of 30-second, all-out sprints altered nearly a quarter of the proteins measured immediately afterward. Moderate, continuous cycling for 90 minutes altered fewer than one-quarter of one percent. And while moderate running on a treadmill changed more proteins than cycling, it still altered far fewer than a quick sprint. Sprinting triggered changes in more than 200 metabolites. It also caused an immediate surge of proteins involved in blood-vessel growth, tissue remodeling, and hormonal signaling. Some of these proteins appear to enter the bloodstream through an expedited cell signaling process known as ectodomain shedding—rather than being newly made and secreted, portions of proteins already sitting on the cell surface were cleaved off and rapidly released into circulation. The researchers also found that human fat cells exposed to blood collected after sprinting underwent extensive changes in gene activity, shifting how the cells process fuel, respond to hormones, and sense nutrient availability. Not so with moderate exercise which produced a more modest response. It was not until three hours after completing that exercise that a meaningful wave of the fatty acids and liver-derived proteins that typically appear in response to the demands of endurance exercise were found in the bloodstream. Ultra-processed foods linked to higher prostate cancer risk in men Florida Atlantic University, August 12 2026 (News-Medical) Ultra-processed foods (UPFs) account for nearly 60% of adults' and 70% of children's energy intake in the United States. New research from Florida Atlantic University provides evidence that men with higher consumption of UPFs have increased risks of prostate cancer. Published in The American Journal of Medicine, the study provides analyses from a large and nationally representative data from 17,024 U.S. men ages 18 and older. Researchers used two 24-hour dietary recalls to calculate the percentage of daily calories participants consumed from UPFs. Men in the three higher-consumption groups of UPFs had a 29% greater risk of prostate cancer, while those in the two highest-consumption groups had a 30% greater risk, compared to those in the lowest consumption group. After adjustments, the increased risk remained significant, ranging from 24% to 31%. Men with the highest UPF intake alone had a possible 34% higher risk, although the finding did not reach statistical significance, potentially reflecting the smaller number of prostate cancer cases in that group. Cinnamon Supplementation Associated With Lower Blood Sugar and Cholesterol in Review of 21 Meta-Analyses Lanzhou University Second Clinical Medical College (China), August 11 2026 (Natural News) A pooled analysis of 21 meta-analyses, including 139 placebo-controlled comparisons, found cinnamon supplementation associated with lower HbA1c, total cholesterol, LDL cholesterol, and blood pressure, according to a report published in Frontiers in Nutrition. The report stated that the strongest effects occurred at daily amounts above 1.5 grams, or roughly three-quarters of a teaspoon, for periods of two months or less. Compared with placebo, cinnamon supplementation was tied to a measurable reduction in HbA1c, the blood test doctors use to track blood sugar control over the previous several months, the article stated. Total cholesterol and LDL cholesterol also declined, and blood pressure readings improved, according to the analysis. Ceylon cinnamon, sometimes labeled 'true cinnamon,' contains only trace amounts of coumarin, while Cassia cinnamon, the variety commonly found on supermarket shelves, contains higher levels, according to the article. For daily use, experts cited in the report recommend limiting Cassia cinnamon to about one teaspoon or less, with occasional larger amounts considered unlikely to cause harm. Healthy lifestyle cuts hearing impairment risk by 14%, metabolism is key driver Fudan University (Japan), August 12 2026 (News-Medical) Hearing impairment ranks as the third largest contributor to global disability among sensory disorders, with prevalence rising across younger and middle-aged populations alongside older adults. The Fudan University team conducted an analysis of 441,844 UK Biobank participants aged 40 to 69 at baseline, with a median follow-up of 14.22 years. The researchers constructed a comprehensive lifestyle score spanning seven behaviors: smoking status, alcohol consumption, physical activity, sleep duration, sedentary time, social engagement, and dietary supplement use. Over the study period, 20,743 incident cases of hearing impairment were documented. Participants with an ideal lifestyle had a 14% lower risk of developing hearing impairment than those with a poor lifestyle. Among individual factors, smoking cessation offered the greatest preventive benefit, followed by reduced sedentary time; dietary supplement use showed no protective effect, and social contact frequency was not significantly associated with hearing risk. The study's core insight emerges from its quantitative mediation analysis, which revealed metabolic dysfunction as the dominant biological pathway linking lifestyle to auditory health. Metabolic biomarkers–most notably BMI and HDL-c–mediated approximately 16.5% and 14.0% of the total lifestyle–hearing association respectively. In contrast, each inflammatory marker contributed less than 6% of the effect, playing only a secondary role.
Support the show to get full episodes, full archive, and join the Discord community. The Transmitter is an online publication that aims to deliver useful information, insights and tools to build bridges across neuroscience and advance research. Visit thetransmitter.org to explore the latest neuroscience news and perspectives, written by journalists and scientists. Read more about our partnership. Sign up for Brain Inspired email alerts to be notified every time a new Brain Inspired episode is released. To explore more neuroscience news and perspectives, visit thetransmitter.org. Marco Facchin is a postdoctoral philosopher of neuroscience and cognitive sciences more broadly at the University of Antwerp. He and his colleague Farid Zahnoun recently hosted a workshop called Beyond Neuro-computationalism with themselves and a handful of speakers, almost all of whom have been on Brain Inspired. In that workshop, they discussed many topics around this sort of forever ongoing reassessment in neuroscience and philosophy about how best to think about cognition, the role of brains, embodied, enactive, embedded, extended - known together as 4E cognition - how much biological detail matters for a good explanation, and so on. The talks from that workshop are online, and I'll link to them in the show notes. So today Marco and I discuss how that all went, and many of the topics and themes I just mentioned, plus his own work and ideas along those lines. Marco Facchin Social: @marcofacchin.bsky.social Beyond neuro-computationalism talks. Why can't we say what cognition is (at least for the time being) Predictive processing and anti-representationalism Defusing the Representation-Hungry Challenge Structural representations do not meet the job description challenge Structure and function in the predictive brain Read the transcript. 0:00 - Intro 3:30 - Beyond neuro-computationalism 14:02 - Vicente Raja motifs 17:58 - 4E cognition 32:36 - Philosophy and neuroscience 42:18 - The problem with predictive processing 48:56 - Role of AI in understanding brains and minds 54:05 - Metabolic constraints 1:07:58 - A philosopher's view of neuroscience 1:13:27 - A-lieving and AI 1:25:47 - AI consciousness
For so many people, the thought of memory loss or cognitive decline feels frightening. But today's guest shares an empowering message: there is so much we can do through our daily choices to support brain health and reduce risk. I'm joined by Dr. David Perlmutter, board-certified neurologist, leading brain health expert, and bestselling author of Brain Defenders, to discuss what we can do today to protect our brains as we age. We explore the important shift in how we understand brain health, looking at the bigger picture of immunometabolism, metabolic health, inflammation, and the environment that influences the brain long before symptoms appear. Dr. Perlmutter explains why habits that support the entire body, including blood sugar balance and reduced inflammation, can also support cognitive health. He also shares exciting areas of research and reminds us that even small changes can create meaningful improvements over time. Just like we can take steps to support our bones, we can also support our brains through the choices we make every day. "Your brain's destiny is in your hands. It's based upon the choices that you are going to make every single day. A cure for dementia is not going to be given to you in the form of a medication." ~ Dr. David Perlmutter In this episode: - [03:22] - The new science of brain health and immunometabolism - [11:19] - Metabolic health and its impact on cognitive decline - [17:26] - Blood sugar, insulin resistance, and brain health - [28:35] - How to protect your brain as you age - [31:37] - Lab tests for proactive brain health - [39:15] - Environmental toxins, plastics, and brain health - [45:26] - Emerging therapies and the future of brain protection - [52:08] - Resources from Dr. Perlmutter Resources - Osteoporosis Exercises to Strengthen Your Bones and Prevent Fractures - https://tinyurl.com/mystrongbonesexercises - Dr. Perlmutter's new book, Brain Defenders - https://drperlmutter.com/books/brain-defenders/ - Dr. Perlmutter's website - https://drperlmutter.com/ More about Margie - Website - https://margiebissinger.com/ - Facebook - https://www.facebook.com/p/Margie-Bissinger-MS-PT-CHC-100063542905332/ - Instagram - https://www.instagram.com/margiebissinger/?hl=en DISCLAIMER – The information presented on this podcast should not be construed as medical advice. It is not intended to replace consultation with your physician or healthcare provider. The ideas shared on this podcast are the expressed opinions of the guests and do not always reflect those of Margie Bissinger and Happy Bones, Happy Life Podcast. *In compliance with the FTC guidelines, please assume the following about links on this site: Some of the links going to products are affiliate links of which I receive a small commission from sales of certain items, but the price is the same for you (sometimes, I even get to share a unique discount with you). If I post an affiliate link to a product, it is something that I personally use, support, and would recommend. I personally vet each and every product. My first priority is providing valuable information and resources to help you create positive changes in your health and bring more happiness into your life. I will only ever link to products or resources (affiliate or otherwise) that fit within this purpose.
I am delighted to have Jessie Inchauspe, the Glucose Goddess, joining me on the podcast today! Metabolic health is my passion! It is a huge focus of my work, and Jessie is truly a gift in this space! She is a rising-star author and biochemist with a clear, accessible way of explaining the science behind glucose metabolism. Jessie joins me today to discuss the impact of glucose metabolism and spikes. We dive into her background and how an accident created her pain-to-purpose story. We discuss the role of continuous glucose monitors and how glucose spikes impact our mitochondria, inflammation, and oxidative stress. We get into glycation and aging, how weight gain is a protective aspect of glucose spikes- or hyperglycemia, and the role of vinegar, movement, and fiber. We also talk about Jessie's new book, her opinions on fasting, and so much more. I loved interviewing Jessie! Her enthusiasm is contagious, and it is easy to understand why she is such a beloved author in the health and wellness space! IN THIS EPISODE YOU WILL LEARN: Jessie shares how an accident led her to where she is today. How a continuous glucose monitor changed everything for Jessie. How Jessie developed her simple principles to steady glucose levels. What is the purpose of glucose in the body? How do glucose spikes impact our mitochondria? Jessie shares a fascinating vinegar hack to reduce the side effects and symptoms of glucose spikes. How being metabolically unhealthy impacts the aging process. The benefits of having savory breakfasts and eating vegetables first with every meal. Jessie talks about her new book, The Glucose Goddess Method. How gaining weight protects our bodies from the impact of glucose spikes. How walking or moving after meals balances blood sugar levels. Why is blood sugar so important? Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia's website. Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. Purchase Cynthia's book, The Menopause Gut. Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Connect with Jessie Inchauspe On her website Instagram
What if your "chemical imbalance" was never actually in your brain — but on your plate? Dr. Georgia Ede is a Harvard trained psychiatrist who began to experience a host of mystery symptoms in her 40s, including fibromyalgia, migraines, chronic fatigue syndrome, and IBS. When she got relief after experimenting with her diet, she began her path of nutritional studies & later became a nutritional psychiatrist. In this episode, she covers questionnaire collecting vs research, a warning about experimenting on yourself, chemical imbalances vs inflammation & 3 tests you can do at home. This episode originally aired on July 8, 2024. If you liked this episode, you'll also like episode 251: FOOD ADDICTION: CHARACTER FLAW OR REAL DEPENDENCE? [REMASTERED] Guest:https://www.instagram.com/georgiaedemd/https://twitter.com/GeorgiaEdeMDhttps://www.diagnosisdiet.com/https://www.facebook.com/GeorgiaEdeMdhttps://www.linkedin.com/in/georgiaedemd/ Sponsors: https://www.historicpensacola.org/about-us/ 1:31 Skeptical Psychiatrist's Turning Point3:11 Why Nutrition Studies Lie5:38 Rethinking Chemical Imbalances7:10 Metabolic vs Nutritional Psychiatry8:52 Two Diets, Two Goals11:12 Testing Diets in Prisons?12:04 How Fast Results Come14:05 Special Forces Eat Keto15:00 Is Inflammation to Blame?18:14 Try 30 Carbs a Day21:02 Self-Experimenting Without a Doctor24:25 Test Your Insulin at Home28:58 Does Red Dye Cause ADHD?31:06 The Chocolate Craving Mystery34:00 Inside Food Addiction Research39:32 Escape the Glucose Rollercoaster42:11 Her 90-Year-Old Mom's Keto Win46:08 Hope Is on the MenuRequest to join my private Facebook Group, MFR Curious Insiders: https://www.facebook.com/share/g/1BAt3bpwJC/Follow me in all the places:https://www.meredithforreal.com/ https://www.instagram.com/the_curiousintrovert/ meredith@meredithforreal.comhttps://www.youtube.com/meredithforreal https://www.facebook.com/curiousintrovert
In this episode, I'm breaking down the foundational blueprint I believe every woman needs for aging powerfully, not just gracefully. After three decades in this industry (and a lifetime of paying attention to my own body), I've distilled it down to seven pillars that show up again and again with my clients, students, and community. What we cover: Muscle & movement — why building muscle after 35 is your longevity organ, your insulin sink, and your protection from falling, not just an aesthetic goal Metabolic health — the blood sugar conversation hiding underneath fatigue, weight that won't shift, and mood swings, and why stable blood sugar is a longevity practice, not a diet Hormonal intelligence — learning to understand what your hormones are communicating instead of fighting or fearing them Nutrition fundamentals — why consistent eating and proper protein distribution matter more than any "perfect" diet Recovery & sleep — why sleep is where the real repair work happens, and practical ways to support it (especially for shift workers) Nervous system & stress — why chronic low-grade stress is one of the most underestimated accelerants of aging Identity & purpose — my personal favorite pillar, and the one most health conversations skip entirely Let's dive in! Thank you for joining us today. If you could rate, review & subscribe, it would mean the world to me! While you're at it, take a screenshot and tag me @jennpike to share on Instagram – I'll re-share that baby out to the community & once a month I'll be doing a draw from those re-shares and send the winner something special! Click here to listen: Apple Podcasts – CLICK HERESpotify – CLICK HERE This episode is sponsored by: withinUs | Use the code JENNPIKE20 at withinus.ca for a limited time to save 20% off your first order and 20% off your first subscription order St. Francis | Go to stfrancisherbfarm.com and save 15% off your all your orders with code JENNPIKE15 Eversio Wellness | Go to eversiowellness.com/discount/jennpike15 and save 15% off every order with code JENNPIKE15 /// not available for "subscribe & save" option Free Resources: Free Perimenopause Support Guide | jennpike.com/perimenopausesupport Free Blood Work Guide | jennpike.com/bloodworkguide The Simplicity Sessions Podcast | jennpike.com/podcast Get 20% on thewalkingpad.com using code "JENNPIKE20" Metabolic Guide | jennpike.com/metabolic-guide Get discounts at happybumco.com using code "JENNPIKE" *code doesn't apply with Black Friday sale* Programs: Ignite: Your 8-Week Body Transformation Program | https://jennpike.com/ignite The Peri & Menopause Project - Join the Waitlist | jennpike.com/theperimenopauseproject Synced Virtual Fitness Studio | jennpike.com/synced Services: Work With Jenn | https://jennpike.com/work-with-jenn/ Functional Testing | jennpike.com/testing-packages Business Mentorship | The Audacious Woman Mentorship: jennpike.com/theaudaciouswoman Connect with Jenn: Instagram | @jennpike Facebook | @thesimplicityproject YouTube | Simplicity TV Website | The Simplicity Project Inc. Have a question? Send it over to hello@jennpike.com and I'll do my best to share helpful insights, thoughts and advice.
This isn't an anti-GLP-1 episode. It's an anti-“here's your injection, see you in six months” episode. In this episode of Root Cause Radio, we break down how GLP-1 medications work, including semaglutide, the dual GLP-1/GIP agonist tirzepatide, and the investigational triple agonist retatrutide. We explain how these medications truly work (and how some may work better than others), and how they influence appetite, fullness, blood sugar, gastric emptying, fat metabolism, and energy expenditure.We also explore the parts of GLP-1 use that are too often ignored:• Undereating, nutrient deficiencies, and inadequate protein intake• Muscle loss and changes in body composition• Nausea, constipation, reflux, bloating, and impaired gut motility• Potential consequences for women's hormones, menstrual cycles, and fertility• Gallbladder, pancreatic, kidney, and dehydration concerns• Reduced pleasure, motivation, and possible anhedonia• Metabolic adaptation and weight regain after stopping• The emerging conversation around low-dose or “microdosed” GLP-1 use for conditions such as endometriosis, MCAS, and autoimmune diseaseMost importantly, we discuss what responsible GLP-1 care should actually look like: adequate calories and protein, resistance training, micronutrient monitoring, proactive GI support, individualized dosing, body-composition assessment, and a transition plan that begins before the medication is stopped.GLP-1 medications can be valuable tools- let's know what they really do, how they work, and how do use them responsibly. My Website & Work with Me: Instagram: www.instagram.com/faithandfitwww.upliftfitnutrition.comEmail for coaching & phone consults: laceydunn@upliftfitnutrition.com & fitandfaith@gmail.comOrder my book "The Women's Guide to Hormonal Harmony" on amazon! Anya Rosen's info:Website: https://birchwell.clinic/aboutInstagram: https://www.instagram.com/anyaargosh/Email: anya@birchwell.clinic
Intermittent fasting and periodic prolonged fasting may be among the most beneficial things you can do for your health. Discover the benefits of fasting, the best intermittent fasting patterns, how to break a fast, and what happens to your body when you fast.0:00 Prolonged fasting 1:35 Intermittent fasting2:44 Benefits of fasting3:35 Ketones and fat burning4:17 Growth hormone 4:30 Extended fasting benefits 4:55 16:8 fasting and other fasting patterns5:27 Spermidine 5:52 Refeeding after a fast6:07 Fasting and stem cells6:30 How to break a fast6:54 Meal timing and insulin resistance 8:26 Fasting and menstrual cycles 9:02 Fasting and menopause 9:39 Fasting and PCOS 10:29 Prolonged fasting and testosterone11:17 Should I exercise while fasting?
Send us Fan MailDr. Jocelyn Foran is a Canadian medical doctor and Staff Anesthesiologist at Nova Scotia Health Authority, holding a Fellowship from the Royal College of Physicians and Surgeons of Canada (FRCPC) and a Diplomat of the American Board of Obesity Medicine.Through her private practice, Upstream Metabolic Medical, she promotes ketogenic and carnivore diets as treatments for chronic disease and metabolic conditions — dietary approaches that remain contested within mainstream nutrition science and are not endorsed by major public health bodies.While her clinical background is in anesthesiology rather than nutrition or dietetics, she has pursued additional training as a Metabolic Health Practitioner through the Nutrition Network, an organization that advocates low-carbohydrate diets.Metabolism is the process of turning food into form and function- yes, we ARE what we eat. Our metabolism is the core to our health, balancing everyday building (anabolism) with the breakdown of cells (catabolism). In our 21st-century toxic food environment, many of us are now living with metabolic dysfunction and chronic diseases that result: high blood pressure, obesity, insulin resistance, diabetes, infertility, autoimmune illnesses, mental illnesses and cancer. These chronic diseases are not cured, but rather “managed” with medications, often for the rest of our lives.Metabolic coaching focuses on root cause healing to address and reverse chronic illnesses, empowering patients to improve their health by addressing lifestyle issues.Find Dr. Jocelyn Foran at-https://www.metabolicmedical.ca/aboutIG- @MetabolicMedicalFB- @Metabolic MedicalFind Boundless Body at-myboundlessbody.comBook a session with us here!
If you want a healthy future into old age, you need a healthy liver. Fortunately, it's extremely robust and pretty low maintenance, considering how much crazy complicated stuff it does. But at least 1 in 4 Americans has liver dysfunction, which will slowly steal some of their agency of what they're able to do as they get older. I think it's worth 20 minutes of your time to learn how to love and protect your liver. Did you know one of your liver's best protectors is estrogen? Come to my website: www.healthcouragecollective.comAre you ready to give your cells their best chance to not have to stop living before they die by allowing them access to physiologic levels of hormones, but aren't sure how to even get started? Join the waitlist for my new beta program here and help me figure out how best to help wonderful women like you get the hormone care they deserve!Join the Waitlist HereCome visit me: www.healthcouragecollective.comemail me: healthcouragecollective@gmail.com
Metabolic health, remission, and real nutrition strategies: on this episode of the Real Health Podcast, Dr. Ron Hunninghake and Jen Nolan of Remission Nutrition explore what it actually takes to rebuild your health through food."So it's not always about, oh, I have a diagnosis and I'm doing this thing, and then I'll be in remission. But what about re-mission?" said Jen Nolan.In this episode of the Real Health Podcast, Dr. Ron Hunninghake sits down with Jen Nolan, owner and director of Remission Nutrition, to explore how nutrition builds metabolic health and lays the foundation for lasting wellness and remission. Remission, Jen explains, isn't just a cancer conversation: the same principles apply to diabetes and other chronic conditions rooted in metabolic health, which is why the conversation broadens from there into practical nutrition that works for everyone.Discover practical strategies for overcoming common barriers to healthy eating: convenience, time, and food addiction, and learn how to retrain your taste buds for real, whole foods. From intermittent fasting and ketogenic diets to simple home cooking techniques and smart shopping habits, Jen and Dr. Ron share actionable guidance for building a sustainable nutrition plan that supports metabolic health and long-term vitality.Whether you're thinking about remission from cancer, diabetes, or another chronic condition, or simply want to eat in a way that supports your metabolic health, this conversation offers practical, food-first strategies you can start using today.Chapters:0:00 Intro[1:15] Remission beyond cancer: diabetes and chronic conditions[4:10] Barriers to healthy eating: convenience, time, and food addiction[8:20] Home cooking techniques and smart shopping habits[12:40] Trends, Intermittent fasting, and ketogenic diets[17:40] Building a sustainable nutrition plan
Over a week ago, I stood at 19,341 feet on the roof of Africa, Mount Kilimanjaro. It was the hardest thing I've ever done, harder than any Ironman or marathon. But somewhere between the rainforest and the summit, I realized I wasn't just climbing a mountain. I was watching my patients' weight loss journeys play out in front of me. In this episode, I'm sharing the first four lessons Kilimanjaro taught me about health, resilience, and what it actually takes to accomplish something hard. From the invisible prep work no one applauds, to why "pole pole" (slowly) is the secret to going further, this episode reframes what progress really looks like. Your summit isn't built in one dramatic moment. It's built in thousands of small, unglamorous decisions, the walk after dinner, the water instead of soda, the appointment you finally book. You'll learn why plateaus and slow progress aren't failures, why community and encouragement matter as much as calories, and why the hardest and most important step is simply saying yes. Episode Highlights: Why the journey begins long before the mountain, or the diet, ever starts The invisible decisions behind every success story nobody sees Lesson two: why "pole pole" (slowly) is the pace that actually gets you there Why our culture's obsession with fast results works against how bodies really change Lesson three: why encouragement on the journey matters as much as the plan itself Lesson four: why saying yes before you feel ready is the hardest and most important step Why no single meal, workout, or medication changes your life, consistency does The one question to ask yourself this week to keep moving forward Connect with Dr. Alicia Shelly: Website | drshellymd.com Facebook | www.facebook.com/drshellymd Instagram | @drshellymd Linked In | www.linkedin.com/in/drshellymd Twitter | @drshellymd About Dr. Alicia Shelly Dr. Alicia Shelly was raised in Atlanta, GA. She received her Doctorate of Medicine from Case Western Reserve University School of Medicine in Cleveland, OH. Dr. Shelly has been practicing Primary Care and Obesity medicine since 2014. In 2017, she became a Diplomat of the American Board of Obesity Medicine. She is the lead physician at the Wellstar Medical Center Douglasville. She started a weekly podcast & Youtube channel entitled Back on Track: Achieving Healthy Weight loss, where she discusses how to get on track and stay on track with your weight loss journey. She has spoken for numerous local and national organizations, including the Obesity Medicine Association, and the Georgia Chapter of the American Society of Metabolic and Bariatric Surgeons. She has been featured on CNN, Fox 5 News, Bruce St. James Radio show, Upscale magazine, and Shape.com. She was named an honoree of the 2021 Atlanta Business Chronicle's 40 under 40 award. She also is a collaborating author for the, "Made for More: Physician Entrepreneurs who Live Life and Practice Medicine on their own terms''. Resources: FREE! Discover the 5 Reasons Your Weight-Loss Journey Has Gotten Derailed (And How To Get Back On Track!)
In this School of Doza episode, Nurse Doza opens the Metabolic Series with the adrenal glands — and why you may feel tired all day, crash between 2 and 4 PM, and wake up unrested. He explains how chronic stress can keep the body stuck in fight-or-flight, why that pattern is hard to shift, and the daily levers he leans on: belly breathing, less screen time at night, and morning sunlight. Then he breaks down Zen by MSW Nutrition — adrenal glandular plus four adaptogens — for stress support. FEATURED PARTNER Zen by MSW Nutrition is built in three layers rather than a single botanical: **125 mg of adrenal glandular tissue** (bovine, sourced from Argentina), **four standardized adaptogens** — Asian ginseng, rhodiola, eleuthero, and schisandra — plus **cofactor nutrients** (vitamin C, B6 as P5P, and pantothenic acid). Licorice rounds out the 9-ingredient formula. It's the supplement Nurse Doza reaches for when the goal is supporting the adrenal glands and the body's stress response, instead of layering more caffeine on top of a depleted system.
Why does eating sugar sometimes leave you more exhausted than before you ate it? Metabolic health researcher Chris Mearns sits down to explain the science behind fructose, cellular energy, and the compound that changed his own relationship with cravings.Chris Mearns is a metabolic health researcher and founder of LIV3 Health, focused on how fructose metabolism affects cellular energy production. He explains how the enzyme fructokinase converts dietary fructose into uric acid, degrading ATP and shifting cells into a defensive, energy-conserving state linked to fatigue, fat storage, and chronic cravings. The conversation covers how this same mechanism connects to gout, a disease historically limited to those with access to sugar and alcohol, and why calorie restriction or GLP-1 medications often fail to address the underlying signal. Chris also discusses luteolin, a flavonoid identified as a fructokinase inhibitor, the personal experiment that led him to develop it into a supplement called Sugar Shield, and emerging research linking fructokinase inhibition to cognitive decline prevention.The conversation also covers why fruit affects the body differently than refined sugar, and what a realistic timeline looks like once the underlying signal is actually addressed.It's a practical look at why willpower alone rarely fixes chronic cravings, and what the research says might work instead.✨ Get Sugar Shield (use code DRJOY for 15% off your first purchase): https://liv3health.com/joykong Chris talks about:02:29 Why every disease shares one root cause05:44 Mitochondria: your body's real engine08:12 Reframing fructose as a signaling molecule10:32 How fructokinase turns ATP into uric acid13:03 Bears, torpor, and ancient fructose survival19:12 The organs fructose hits hardest20:03 Fructose, uric acid, and gout23:54 Why GLP-1s don't fix the engine26:17 Pharma's race for fructokinase inhibitors34:56 Lutein: a natural fructokinase inhibitor43:23 Fructose and the Alzheimer's connection46:01 First steps to reset your metabolismAdditional Resources✨ Visit LIV3 Health: https://liv3health.com ✨ Follow LIV3 Health on Instagram: https://www.instagram.com/tryliv3/ ✨ Follow Chris Mearns on Instagram: https://www.instagram.com/chris_liv3/ ✨ Subscribe to Chris Mearns' YouTube channel, The Fructose Model: https://www.youtube.com/@thefructosemodel Visit My Clinic: Chara Health
A physical therapist is evaluating a patient in the outpatient clinic who reports progressive fatigue, orthostatic dizziness, and generalized weakness. During the exam, the therapist observes darkened pigmentation over the patient's knuckles, elbows, and the lining of the mouth. Which of the following conditions is MOST consistent with these findings? Find it all out in the podcast! Be prepared for the NPTE so that you can pass with flying colors! Check out www.ptfinalexam.com/podcast for more information and to stay up-to-date with our latest courses and projects. #Npte #PT #ptboards #crushtheNPTE #study #studygram #spt #ptstudent #ptlife #sptprobs #physicaltherapystudent #physicaltherapy #physio #physiotherapist #ptlife #ptstudentstudy
Menopause Mastery | Perimenopause vs. Menopause: What Most Women Never Get Told | Episode 290
Dr Kishlay joins me on this episode discussing his journey into Carnivore, his metabolic practice, myths around Carnivore and the types of cases he sees. He has been carnivore for more than 6 years and is an OG of Indian Carnivore Doctors. To get in touch with him, visit his IG - @metabolicdr.k . You can also visit his YouTube channel - https://www.youtube.com/@metabolicdr.k1650
Part Two – The FutureYou Blueprint™: Restoring Biological Communication Once you recognize the patterns, what's next? In Part 2 of The FutureYou Blueprint™ Educational Series, Debbie introduces the philosophy behind The FutureYou Blueprint™ and explains why lasting health isn't about chasing symptoms—it's about restoring biological communication before dysfunction becomes disease. In this episode, you'll discover: Why restoring communication always comes before optimization The philosophy behind The FutureYou Blueprint™ Why personalized biological investigation is essential because every body tells a different story How The FutureYou Blueprint™ provides a personalized roadmap to restore resilience and support healthy aging Why no podcast, protocol, or social media post can replace a personalized approach to your biology This episode introduces the thinking behind Debbie's proprietary framework while showing why true health transformation begins with understanding your unique patterns—not following someone else's plan. Because biology is personal. Your roadmap should be too. Ready to create your own FutureYou Blueprint™? Visit www.debbiepotts.net to learn more about personalized coaching, Metabolic Pattern Analysis™, functional lab interpretation, and The FutureYou Blueprint™ programs.
A cardiac surgeon who's performed thousands of open-heart operations says most of his patients didn't have to be there — and the culprit isn't cholesterol, it's metabolic health.In this episode of Health Longevity Secrets, Robert Lufkin MD sits down with Dr. Philip Ovadia, board-certified cardiac surgeon and author of the new book "Stay Off My Kitchen Table." Once morbidly obese and prediabetic himself, Ovadia lost nearly 100 pounds and rethought everything he was taught about heart disease. He explains why "meat is medicine," how red meat got vilified by bad science, what really drives heart disease, and how his nationwide telehealth practice is rebuilding primary care around metabolic health.Chapters:00:00 — Introduction01:34 — Why a Heart Surgeon Wrote "Stay Off My Kitchen Table"04:54 — Do You Need to Eat Meat? Nutrient Density and Bioavailability07:30 — Meat Is Medicine: Why Red Meat Was Vilified09:38 — How Bad Epidemiology Made Meat the Villain12:43 — Red Meat Down 40%, Heart Disease Worse: What That Tells Us14:23 — Ovadia's Own Journey: Obese, Prediabetic, and Gary Taubes15:54 — Why Medical Schools Resist This (and What's Changing)19:01 — RFK Jr, Trump, the New Food Pyramid and realfood.gov21:38 — Leaving Employed Surgery for a Telehealth Practice25:24 — Metabolic Care Beyond the Heart: Building Primary Care31:38 — What Telemedicine Patients Actually Experience37:01 — It's Not Just What You Eat — It's What You Absorb38:50 — Gut Health, Anti-Nutrients, and the NAD Supplement Problem42:37 — Best Wearables: Why the CGM Tops the List44:11 — Empowering Patients to Take Back ControlKey takeaways:Metabolic health — not cholesterol — is the primary driver of heart disease, and most heart surgery is preventable through diet and lifestyle."Meat is medicine": red meat was vilified largely by poorly done epidemiologic science layered with political and economic interests.U.S. red meat consumption has fallen ~40% since the 1950s–60s, yet heart disease has gotten worse — strong evidence meat isn't the cause.It's not just what you eat, it's what you absorb: gut health, bioavailability, and plant anti-nutrients all shape your results.The continuous glucose monitor (CGM) is the single most powerful wearable for understanding how food and lifestyle affect your metabolic health.Studies & sources:"Stay Off My Kitchen Table" by Dr. Philip Ovadia (with Joshua Lisik) — ovadiahearthealth.com"Stay Off My Operating Table" by Dr. Philip Ovadia — GoodreadsOvadia Heart Health (nationwide telehealth practice) — ovadiahearthealth.comNew U.S. dietary guidelines & food pyramid — realfood.govGary Taubes (author and science journalist) — garytaubes.comDr. Lufkin's book "Lies I Taught in Medical School": robertlufkinmd.com/lies⭐ Enjoying the show? Please leave a 5-star review on Apple Podcasts — it takes 30 seconds and helps more people discover the science of health and longevity. Thank you!New episodes every other Tuesday. Subscribe so you don't miss one.Continue this conversation on Substack: https://robertlufkinmd.substack.comLies I Taught In Medical School — Free sample chapter: https://www.robertlufkinmd.com/lies/Web: https://www.robertlufkinmd.comYouTube: https://www.youtube.com/robertlufkinmdX: https://x.com/robertlufkinmdInstagram: https://www.instagram.com/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinLinkedIn: https://www.linkedin.com/in/robertlufkinmd/
Aging after 50 doesn't have to be an uphill battle. Discover the single greatest marker of aging and longevity, how to work with your body to age gracefully, evidence-based longevity tips, and the critical role of mitochondrial health.0:00 Aging gracefully after 500:38 VO2 max and longevity1:26 Metabolic health explained2:45 Aging biomarkers after 503:41 The truth about cholesterol and longevity6:18 Genetics and aging6:59 No energy for exercise 7:35 The top anti-aging supplements8:28 Longevity tips Download Dr. Berg's Free Daily Health Routine: https://drbrg.co/4tO9nV9
What if most chronic illness isn't caused by bad luck or genetics, but by the daily choices we make?In this episode of Coaching In Session, Michael Rearden sits down with holistic nutritionist, radio host, and wellness coach Tammy Cuthbert Garcia to discuss the connection between lifestyle, mindset, nutrition, and long-term health. They explore why symptoms should be viewed as signals rather than problems to suppress, how personal responsibility impacts wellness, and why true healing often starts by addressing root causes instead of managing symptoms.The conversation explores how modern healthcare often focuses on symptom management while overlooking prevention, education, and personal accountability. Tammy explains why awareness is the first step toward transformation and how individuals can begin making sustainable changes that support long-term wellness.Listeners will gain practical insights into improving health through consistent habits, better decision-making, community support, and a deeper understanding of how the body responds to lifestyle choices.What You'll LearnWhy lifestyle choices play a major role in long-term healthHow symptoms can serve as valuable signals from the bodyThe connection between mindset, identity, and healingWhy metabolic health matters more than many people realizeHow childhood experiences influence food behaviorsThe importance of personal responsibility in wellnessPractical ways to create sustainable health habitsWhy community support accelerates transformationKey Takeaways✅ Holistic nutrition focuses on lifestyle, habits, and long-term wellness.✅ Awareness is the first step toward improving your health.✅ Symptoms often reveal underlying issues that need attention.✅ Food beliefs and family culture shape lifelong habits.✅ Metabolic health plays a major role in overall well-being.✅ Personal responsibility creates lasting change.✅ Mindset and identity can either support or hinder healing.✅ Consistency matters more than perfection.✅ Community support can accelerate growth and transformation.✅ Small daily choices compound into significant health outcomes.Tammy Garcia's Guest Links & ResourcesWebsite – https://naturallyinspiredradio.com/X – http://x.com/tammycuthbertgInstagram – http://instagram.com/tammycuthbertgarciaFree Lifestyle Health & Wellness Assessment - https://calendly.com/tammycuthbertgarcia/consciously-clean-assessmentExplore More With Michael ReardenWebsite – https://revenconcepts.com/Podcast – https://coachinginsession.buzzsprout.com/Instagram – https://www.instagram.com/revenconcepts/Work With Michael Reardenhttps://www.revenconcepts.com/
Program notes:0:44 Novel agent for acute pain1:44 Post-abdominal surgery and placebo, low and high dose2:46 Compared to placebo and opioids3:19 Metabolic associated steatotic liver disease4:19 Imaging with two techniques and plasma markers5:19 Imaging and composite scores for staging6:21 Identifying appropriate candidates for clinical trials7:00 Alcohol consumption during pregnancy8:00 Employed, tobacco use, and mental stress predicts9:01 Never tested medicines for AUD in pregnant women9:24 Early detection of Alzheimer's disease with circular RNA10:24 Can it identify those with the disease as well as those at risk11:24 Almost 95% AUC12:20 Use with tau, it was even better13:05 End
Welcome to Episode 318 of Autism Parenting Secrets. Many parents enter this journey searching for the next therapy, treatment, supplement, or breakthrough intervention. While those approaches can absolutely help, Dr. Kurt Woeller believes one of the most common mistakes is pursuing advanced therapies before establishing the foundations that allow them to work. Dr. Woeller is an integrative and functional medicine physician, biomedical autism specialist, educator, author, and Chief Medical Officer of Mosaic Diagnostics. For nearly 30 years, he has helped families and practitioners better understand the underlying factors influencing health, development, communication, behavior, and recovery. In this conversation, he shares the Four Pillars that he believes should remain at the center of every biomedical program: diet, foundational nutrients, gut health, and methylation. He also explains why individualized investigation, thoughtful testing, and consistent implementation matter far more than chasing the latest trend. The secret this week is… Don't Skip The FOUR PILLARS You'll Discover: Why skipping the foundation slows progress (9:12) The FOUR PILLARS every parent should strengthen first (10:47) How to find your child's unique "kryptonite" (30:18) The one test NOT to skip (41:36) Why great parents become great detectives (50:09) About Our Guest: Dr. Kurt N. Woeller, D.O., is an integrative and functional medicine physician and biomedical autism specialist with nearly 30 years of experience. He focuses on complex conditions including autism, autoimmune disorders, and neurological challenges using specialized diagnostics and targeted interventions. He serves as Chief Medical Officer of Mosaic Diagnostics, is the founder of Integrative Medicine Academy, and is the author of multiple books including Autism: The Road to Recovery. Dr. Woeller is a respected educator who has trained thousands of practitioners and continues to lecture internationally on autism, functional medicine, and biomedical intervention. Sunrise Functional Medicine Center Dr. Woeller on Substack Integrative Medicine Academy You Tube Channel Dr. Woeller's Functional Medicine Doc Talk podcast References in this Episode: Mosaic Diagnostics Autism Recovery System James Adams The Personalized Autism Nutrition Plan: Nourishing Hope for Kids with ASD, ADHD, Anxiety, and Neurodevelopmental Delays by Julie Matthews, M.S. Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism, Dr. Jill James et al. Meadow Health Autism Health Summit Medical Academy of Pediatrics and Special Needs (MAPS) Documenting Hope Additional Resources: To learn more about personalized 1:1 support go to www.elevatehowyounavigate.com If you enjoyed this episode, share it with your friends.
Are Your Supplements Actually Doing Anything? With Reed Davis of Functional Diagnostic Nutrition® You don't feel any different after taking them. So...how do you know if your supplements are actually working? It's a question millions of people ask—but according to Reed Davis Founder of Functional Diagnostic Nutrition® (FDN), it may not be the first question you should be asking. In this episode of the Pretty Well Podcast, Reed and I dive into why so many people continue chasing symptoms while the real problem quietly gains traction beneath the surface. He calls it metabolic chaos—the slow, invisible breakdown that can begin years before you're diagnosed with diabetes, heart disease, an autoimmune condition, or another chronic illness. The scary part? Metabolic chaos doesn't announce itself. It quietly churns beneath the surface until one day, it's affecting your life in a big way. We also explore why supplements aren't a substitute for understanding what's really happening inside your body, why masking symptoms (even with supplements) can delay healing, and how functional lab testing can help uncover what's driving your fatigue, digestive issues, inflammation, hormone imbalance, brain fog, and other chronic symptoms. Reed also shares his D.R.E.S.S.® framework—Diet, Rest, Exercise, Stress Reduction, and Supplementation—and explains why getting these foundations right is essential if you want to stop guessing and start making meaningful progress. If you've ever wondered: -Are my supplements doing anything for me? -Why don't I feel any different even though I'm doing all the right things? -Is there a hidden reason I don't feel my best? ...this episode is for you. Timestamps 03:42 How do you know if your supplements are working? 11:18 The hidden danger of metabolic chaos 22:51 Food sensitivities vs. food allergies 35:07 Why pain is a message—not the problem 46:35 Stop chasing symptoms and start asking better questions
Coach Ted talks about the strong draw of choices and habitual behaviors that can be counter to our objectives. (Originally aired 08-28-2024)
Join us for a live Q&A with Dr. Ben Bikman here.For the 100th episode of The Metabolic Link, Ben Bikman, PhD, professor of cell biology and physiology at Brigham Young University and author of Why We Get Sick, returns for a milestone conversation with co-hosts Dominic D'Agostino, PhD, and Victoria Field. Together, they examine what clinicians are measuring, what conventional approaches may be missing, and how the science of metabolic health continues to evolve.Bikman argues that the clinical picture of metabolic health remains glucose-centric and lipid-heavy while the earliest signal, elevated insulin, goes unmeasured. He explains why women stay insulin sensitive at far higher body fat than men and what menopause takes away, why visceral fat is misunderstood, and how a fatty liver can be miscounted as lean mass on a DEXA scan. That last point is why he now says he was wrong about GLP-1 drugs, and why he thinks they should be prescribed as something other than weight loss medication.Questions Answered in This Episode:• Why does standard bloodwork detect metabolic dysfunction so late?• Why are women more insulin sensitive than men at the same or higher body fat?• What actually changes metabolically during menopause?• Is visceral fat inherently dangerous, or is something else going on?• Why did Dr. Bikman change his position on GLP-1 medications?• Should GLP-1 drugs be prescribed as weight loss drugs at all?This milestone episode offers a rigorous, physiology-first look at where metabolic science stands today, and what researchers and clinicians may need to examine next.Thank you for listening, watching, sharing these conversations, and helping us reach 100 episodes. We're incredibly grateful to have you as part of this community.Special thanks to the sponsors of this episode:Genova Connect: Get 15% off any Genova Connect test kit with code METABOLICLINK here.Cowboy Colostrum: Get up to 25% off with code METABOLIC here.iRestore: Get a special discount on the iRestore Illumina face mask with code LINK here.More LinksDr. Ben Bikman's website: benbikman.comInsulin IQ: insuliniq.comYouTube: youtube.com/@benbikmanInstagram: @benbikmanphdFeatured study: White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's DiseaseIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: InstagramFacebookYouTubeLinkedInPlease keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
I had a patient walk into my office recently looking frustrated. She sat down, crossed her arms, and said, "Dr. Shelly, my medication has stopped working. I lost 32 pounds, but for the last six weeks my weight hasn't budged. Am I immune to this medication?" If you've looked at the scale lately and wondered the same thing, this episode is for you. In this episode, I'm walking you through the seven most common reasons weight loss plateaus happen, from still being on a starting dose to hidden medical conditions like thyroid issues or PCOS that can quietly work against you. I'll also break down why protein intake and resistance training matter more than most people realize once a GLP-1 medication kicks in. But here's what matters most: a plateau doesn't mean your medication has failed. Your body is incredibly smart, and adapting is exactly what it's designed to do. You'll learn exactly what's happening biologically during a stall, and the five practical steps to get your progress moving again. Episode Highlights: Why plateaus are a normal, expected part of every weight loss journey, not a sign of failure Why your starting dose may not be your effective dose yet How low protein intake quietly stalls progress and costs you muscle Why resistance training protects the muscle mass your metabolism depends on How untreated sleep issues like sleep apnea can sabotage results The hidden medical conditions, from thyroid issues to PCOS, that can slow weight loss Why hitting a plateau might actually mean you've already succeeded Five practical steps to get moving again when progress stalls Connect with Dr. Alicia Shelly: Website | drshellymd.com Facebook | www.facebook.com/drshellymd Instagram | @drshellymd Linked In | www.linkedin.com/in/drshellymd Twitter | @drshellymd About Dr. Alicia Shelly Dr. Alicia Shelly was raised in Atlanta, GA. She received her Doctorate of Medicine from Case Western Reserve University School of Medicine in Cleveland, OH. Dr. Shelly has been practicing Primary Care and Obesity medicine since 2014. In 2017, she became a Diplomat of the American Board of Obesity Medicine. She is the lead physician at the Wellstar Medical Center Douglasville. She started a weekly podcast & Youtube channel entitled Back on Track: Achieving Healthy Weight loss, where she discusses how to get on track and stay on track with your weight loss journey. She has spoken for numerous local and national organizations, including the Obesity Medicine Association, and the Georgia Chapter of the American Society of Metabolic and Bariatric Surgeons. She has been featured on CNN, Fox 5 News, Bruce St. James Radio show, Upscale magazine, and Shape.com. She was named an honoree of the 2021 Atlanta Business Chronicle's 40 under 40 award. She also is a collaborating author for the, "Made for More: Physician Entrepreneurs who Live Life and Practice Medicine on their own terms''. Resources: FREE! Discover the 5 Reasons Your Weight-Loss Journey Has Gotten Derailed (And How To Get Back On Track!)
Ten pounds in two weeks. No hunger. No craving for coffee or alcohol. This is Jeff's personal, week-by-week account of starting tirzepatide (sold as Zepbound), tracked through blood sugar, cholesterol markers, and a noticeable dimming of everyday motivation and joy. What changed in the first two weeks: appetite, weight, and energy Tracking glucose, LDL, ApoB, and other metabolic markers with a CGM and blood panels Why alcohol and coffee stopped feeling rewarding The emerging link between GLP-1s, dopamine, and the brain's reward circuitry The trade-off between appetite control and a sense of vitality or spark This episode is for anyone weighing GLP-1s for themselves, or curious what the drugs are actually like beyond the headlines. This episode was made possible by: CocoaVia:. Use code COMMUNE2026 for 25% off at CocoaVia.com LMNT: Get a free 8-count Sample Pack of LMNT's most popular drink mix flavors with any purchase at drinklmnt.com/commune. Stemregen: Get 20% off your first order at stemregen.co/commune with the code COMMUNEPOD Vivobarefoot: Try Vivobarefoot risk-free with a 100-day return guarantee, and get 25% off your order at vivobarefoot.com/commune. Stripes: Visit stripesbeauty.com and use the code COMMUNE20 for 20% off our entire product line.
This one came straight out of the DMs. Aaron gets messages from people who are interested in coaching and they usually lay out everything they have been doing and everything they have tried. The same handful of problems keep showing up over and over again, so instead of answering them one at a time, this episode is the full breakdown.The whole thing is built around three buckets. Poor metrics, where the plateau only exists in perception because there was never a baseline, a rate of loss target, or any real objectivity built into the approach in the first place. False plateaus, where the deficit is actually intact but something is muddying the water and making it look like nothing is happening. And true plateaus, where the deficit on paper simply does not match the deficit in reality.If you are coaching yourself through a fat loss phase, this is the episode to have open when the scale stops moving and you are trying to figure out whether to change something or hold the line. Bryan spent a good portion of this one saying he had nothing to add, which is probably the best endorsement it could get. Before that, Bryan talks about the ten day family road trip through the canyons that has him off the mic for the next couple of weeks, and Aaron recaps the boys training trip he put together in Dallas.Covered in this episodeWhy an emotional goal like fat loss needs objective metrics to save you from yourselfEstablishing an actual baseline before you start, and why "intuitive eating" is not a planThe problem with subjective labels like eating healthy or eating goodDaily weigh-ins as data points, not verdicts, and how to use weekly and seven day moving averagesWeighing under identical conditions so you stop importing noise into your own metricsWhy the mirror is a terrible short term progress toolSetting a target rate of loss, 0.5% to 1% of body mass per week, and reverse engineering the timeline from thereWhy the first week whoosh on low carb is gut contents, glycogen, and water, not fatWater retention and inflammation from hard training, travel, poor sleep, sickness, and menstrual cyclesFat loss is not linear, and what a huge week usually means for the week after itThe gut check question: have my actions actually changed, or am I still running it by the book?Getting leaner makes you more sensitive to stress, sleep, and digestionRecomping as an explanation, and why you probably should not hold your breath on itToo much flexibility and macro Tetris, and why more opportunities equal more errorsWhen to suspect user error versus when to actually go get labsOverconfidence from early success and why the corners you cut early stop working laterInversion of control, or too many meals sourced by hands that are not your ownUntracked sauces, oils, bites, tastes, the mom tax, and the zero calorie spray technicalityAlcohol as its own macronutrient and the weekend pattern robbing weekday progressNEAT quietly dropping the longer you diet, with an important caveat on improving healthMetabolic adaptation, why it is real but often overblown, and Pontzer's constrained energy modelBody temperature after meals as a real time readout of energy availabilitySleep as the unsung hero of fat loss and the one natural cheat code that actually existsBuilding in non-progress weeks proactively because life is going to happenAccepting that rigidity has to increase as your ambition increasesTimestamps00:00:00 - Intro: Is Your Fat Loss Stalled? Then Do These00:00:55 - Updates: Bryan's road trip and Aaron's Dallas training trip00:06:25 - Bucket one: poor metrics00:07:25 - Establishing an actual baseline00:10:15 - Weekly averages and seven day moving averages00:13:40 - Setting a target rate of loss: 0.5% to 1% per week00:16:45 - Setting realistic goals and running the math00:19:40 - Bucket two: false plateaus00:22:45 - Fat loss is not linear00:26:20 - Too much flexibility and macro Tetris00:31:00 - Inversion of control00:32:15 - Bucket three: true plateaus00:36:20 - NEAT dropping the longer you diet00:38:00 - Metabolic adaptation: real but often overblown00:41:20 - Sleep is the unsung hero of fat loss00:43:30 - Take homes and building in non-progress weeks Training hard, but don't look like it? Aaron closes that gap ⬇️https://coach.strakernutritionco.com/applicationDone For You Client Check-In System for Coaches ⬇️https://strakernutritionco.com/macronutrient-reporting-check-in-template/Paragon Training Methods Programming ⬇️https://paragontrainingmethods.comFollow Bryan's Evolved Training Systems Programming ⬇️https://evolvedtrainingsystems.comFind Us on Social Media ⬇️IG | @Eat.Train.ProsperIG | @bryanboorsteinIG | @aaron_strakerYT | EAT TRAIN PROSPER PODCAST
The Nurses Report on America Out Loud with Melissa Schreibfeder, BSN, RN, BC-FMP – After navigating years of chronic fatigue, Lyme disease, mold toxicity, and ultimately surviving inflammatory breast cancer, a rare and aggressive form of breast cancer, Amber was forced to look beyond standard approaches and ask deeper questions. What she discovered changed everything. The body is not broken. It is...
On this episode of Vitality Radio, Jared breaks down the probiotic strains he trusts most and explains why not all probiotics deserve the same reputation. Learn the differences between spore-based probiotics, traditional human strains, postbiotics, and beneficial yeast, and discover how each supports digestive health, immune function, metabolism, mental health, gut barrier integrity, and overall wellness. Jared highlights the research behind favorite strains like Bacillus coagulans, Bacillus subtilis, Bacillus clausii, Lactobacillus reuteri, Akkermansia muciniphila, and Saccharomyces boulardii, while also explaining how he selected the ingredients used in Vital Spores, Back on Tract, and GLP-1 Metabolic Optimizer. Whether you're new to probiotics or looking to better understand the science behind today's most popular strains, this episode offers practical guidance to help you make more informed supplement decisions.Products:Back On TractPrecision Probiotic Vital SporesGLP-1 Metabolic OptimizerAdditional Information:448: VR Vintage: The Great Debate in Probiotics: Human Strains vs. Spores 627: GLP-1 Explained Part 1: How to Support Metabolism Without Drugs628: GLP-1 Explained Part 2: The Lifestyle Blueprint for Real Metabolic: OptimizationVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.This podcast is produced by DrTalks.comhttps://drtalks.com/podcast-service/
The Nurses Report on America Out Loud with Melissa Schreibfeder, BSN, RN, BC-FMP – After navigating years of chronic fatigue, Lyme disease, mold toxicity, and ultimately surviving inflammatory breast cancer, a rare and aggressive form of breast cancer, Amber was forced to look beyond standard approaches and ask deeper questions. What she discovered changed everything. The body is not broken. It is...
In this fascinating deep dive, Dr. Scott Watier and Tommy Welling break down a landmark study from Nature Metabolism that tracked what happens inside the body during a seven-day water fast — and the findings go far beyond weight loss. The hosts walk through the three distinct phases of an extended fast, explaining how the first 48 hours switches the body into fat-burning mode, day three triggers a dramatic biological renovation involving immune function, brain health, and cardiovascular protection, and days five through seven begin locking in longer-lasting metabolic changes. One of the most reassuring takeaways is around lean muscle loss — the hosts explain why the apparent muscle decrease during a longer fast is largely water and glycogen, not actual tissue, and how fat loss from the fast is what actually stays off. They also address how everyday fasters can capture some of these deeper benefits through consistent fasting windows, strategic low-carb nutrition opportunities, and proper electrolyte support without needing to do a week-long fast. The episode closes with practical guidance on how to break an extended fast gently — starting with easy proteins and healthy fats — and a challenge to pull out the calendar and schedule your next longer reset before the week is out. Take the NEW FASTING PERSONA QUIZ! - The Key to Unlocking Sustainable Weight Loss With Fasting! Resources and Downloads: SIGN UP FOR THE DROP OF THE ULTIMATE GUIDE TO BLOOD SUGAR CONTROL GRAB THE OPTIMAL RANGES FOR LAB WORK HERE! - NEW RESOURCE! FREE RESOURCE - DOWNLOAD THE NEW BLUEPRINT TO FASTING FOR FAT LOSS! SLEEP GUIDE DIRECT DOWNLOAD DOWNLOAD THE FASTING TRANSFORMATION JOURNAL HERE! Partner Links: Get your FREE BOX OF LMNT hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase here! Get 25% off a Keto-Mojo blood glucose and ketone monitor (discount shown at checkout)! Click here! Our Community: Let's continue the conversation. Click the link below to JOIN the Fasting For Life Community, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply! If you enjoy the podcast, please tap the stars below and consider leaving a short review on Apple Podcasts/iTunes. It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them! Article Link: https://staycuriousmetabolism.substack.com/p/what-happens-to-your-body-during?publication_id=2682303&post_id=201125972&r=wn02o&triedRedirect=true
Insulin resistance — not willpower — is why you can eat 1,200 calories, train, and still not lose weight. Metabolic-health author Ben Azadi joins Liz Roman to explain sugar burning vs. fat adaptation, how to do keto without a gallbladder, why seed oils sabotage "keto" diets, and the reframe that changes everything: you get healthy to lose weight, not the other way around. Real root-cause answers for women who've been told their labs are "normal." Connect with Ben: Instagram | Web | Youtube Get Ben's New Book - Keto Flex *** CONNECT:
Why the Transition Period Is a Critical Window for Dairy Cow Health (02:10 – 10:36) The discussion begins by examining the transition period as one of the most challenging phases in a dairy cow's lifecycle. Research suggests that 30–50% of disease events occur within the first three weeks after calving, making this a key window for understanding and supporting immune function. Dr. Rostoll-Cangiano shares insights into the biological changes that occur during this time, emphasizing the importance of immune adaptation as cows move from late gestation into early lactation. Immune Cell Dynamics and Metabolic Stress in Transition Cows (02:10 – 10:36) Building on this foundation, Dr. Rostoll-Cangiano discusses emerging research on T-cells, dendritic cells, and the differences between systemic and intestinal immune responses. The panel explores how immune cells face substantial metabolic demands after calving, often becoming metabolically constrained as they attempt to support both immune defense and milk production. This competition for energy and nutrients may leave cows more susceptible to disease challenges and environmental stressors during the transition period. Dry Period Management and Prepartum Feed Intake (10:36 – 16:26) The conversation then turns to management practices that can influence transition success before calving. The panel examines how changes in dry matter intake (DMI), bunk space availability, and social stress can significantly affect a cow's metabolic health and immune resilience. Maintaining consistent feed intake and minimizing unnecessary stressors during the dry period are highlighted as key strategies for supporting a smoother transition into lactation. Genetics, Productivity, and Cow Resilience (17:52 – 24:44) The group explores whether modern dairy genetics have altered the balance between productivity and resilience. While today's dairy cows produce substantially more milk than previous generations, the panel discusses whether this increased productivity may come with narrower physiological margins under stress. The discussion highlights the ongoing challenge of improving production while preserving the ability of cows to adapt to metabolic and environmental stressors. Factors Affecting Colostrum Quality and Calf Immunity (28:17 – 35:18) Attention then shifts to colostrum production and quality, with a focus on how maternal health before calving can influence calf outcomes. Topics include the effects of: Metabolic status during the transition period Somatic cell count at dry-off Prepartum inflammation Immunoglobulin G (IgG) concentration Passive transfer and calf health The panel explains how these factors can influence both the quality of colostrum and the long-term health and performance of newborn calves.Nutritional Interventions to Support Transition Cow Performance The experts review research evaluating choline and chromium supplementation as potential tools for supporting transition cow health and improving colostrum production. While published responses have been variable, these nutritional strategies continue to receive attention for their potential role in enhancing metabolic function and immune responses around calving. Precision Dairy Technologies for Managing At-Risk Cows (37:27 – 44:51) The conversation expands into activity monitors and rumination tracking systems. These tools allow producers to identify at-risk cows earlier, monitor behavioral changes, and make more informed management decisions at the individual cow level. By detecting potential problems before clinical signs appear, precision technologies can help improve intervention timing and overall herd health outcomes. Key Transition Cow Management Takeaways The episode concludes with a reminder that, despite advances in dairy research and technology, strong management fundamentals remain the most effective way to support cow health and performance: Maximize dry matter intake Reduce stress and unnecessary regrouping Manage body condition score changes Prioritize cow comfort Provide adequate feeding and resting space Ultimately, while the biology of transition cows is complex, the panel emphasizes that the greatest improvements in health, productivity, and resilience often come from consistently executing proven management practices. Join the Real Science Exchange Please subscribe and share with your industry friends. Invite more people to join us at the Real Science Exchange virtual pub table. Please be sure to register for our upcoming Real Science Lecture Series webinars. Finally, if you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription. Then, email a picture to anh.marketing@balchem.com. Include your size and mailing address. As a result, we'll mail you a shirt.
As part of our summer series, we're revisiting some of the most important conversations we've had on the topics that matter most to our health. And few are more important than heart disease. Heart disease remains the number one cause of death worldwide. Yet despite decades of research, millions of prescriptions, and billions of dollars spent on treatment, many people are still confused about what actually causes it—and what we can do to prevent it. For years, the conversation around heart disease has focused almost entirely on cholesterol. But what if that's only part of the story? In this special compilation episode, you'll hear from Dr. Cindy Geyer of The UltraWellness Center, Dr. Eric Topol, and Dr. Aseem Malhotra as they explore a different perspective on heart disease—one that goes beyond cholesterol and looks at the deeper drivers of cardiovascular risk, including inflammation, insulin resistance, metabolic dysfunction, lifestyle, and early detection. You'll hear why many experts now believe heart disease often begins decades before symptoms appear, why traditional testing can miss important warning signs, and how emerging science is giving us new tools to identify risk earlier than ever before. Most importantly, you'll hear a message that is both practical and hopeful: that many of the factors driving heart disease are within our control, and that prevention remains one of the most powerful tools we have. Let's dive in. View Show Notes From This Episode Sign up for Dr. Hyman's Brainshaping Academy to learn how to nourish the biological systems that support your mental, emotional, and cognitive health https://drhyman.com/products/brainshaping?utm_source=dr_hyman_show&utm_medium=newsletter&utm_campaign=may_27&utm_content=link Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman's Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by BON CHARGE, BIOptimizers, Rho, Made In, Seatopia, and Cozy Earth. Explore red light products at boncharge.com/hyman and enjoy 15% off with code HYMAN. Go to bioptimizers.com/hyman and use code HYMAN to save 15% off your order, plus get a free gift. Explore science-backed products at rhonutrition.com and use code HYMAN for 20% off the entire site. Upgrade your cookware at madeincookware.com and save 10% off your first order with code HYMAN-HIVE. Find a cleaner source of seafood. Check out seatopia.fish/hyman and receive free shipping on your first order. Head to cozyearth.com to save 20% and upgrade all of your daily essentials today. (0:00) The persistence of heart disease and the low-fat diet hypothesis (0:32) Preventing heart disease through diet, lifestyle, and simple behaviors (2:19) Revisiting key conversations on heart disease (3:44) Beyond cholesterol: deeper drivers and risk factors (7:18) Typical workup, treatments, and advances in cholesterol testing (17:48) Metabolic health, hormonal, and inflammatory factors in heart disease (29:37) Advances in cardiovascular diagnostics and AI (31:31) Impact of lifestyle and new pharmacological treatments (36:55) Statins, side effects, and lipoprotein fractionation (40:13) The role of AI, new diagnostics, and Dr. Topol's journey (43:19) Rethinking treatment: diet, industry influence, and the low-fat craze (45:28) Saturated fat, cholesterol, and revisiting the evidence (48:00) Cholesterol in heart disease risk and systematic drug review (52:31) Insulin resistance, cholesterol's role, and mortality (58:31) Challenges in changing medical dogma (1:00:31) Closing remarks and call to action
High cholesterol has been treated as the main cause of heart disease for decades. But over the years, I've changed my mind. Today, I believe cholesterol is only part of the story, and that inflammation, insulin resistance, and metabolic health are often the real drivers of cardiovascular disease. In this encore episode, I'm revisiting one of my most talked-about Office Hours conversations to share how my thinking has evolved and why understanding the root cause of heart disease can completely change the way you approach prevention. In today's episode, I discuss: Why cholesterol alone is a poor predictor of heart disease—and the biomarkers I believe matter even more, including ApoB, lipoprotein(a), inflammation, and insulin resistance The surprising role sugar, refined carbohydrates, and metabolic dysfunction play in driving cardiovascular disease Why two people with the same cholesterol can have dramatically different heart disease risk—and how a personalized approach changes the conversation The nutrition, lifestyle, and testing strategies I use to help reduce inflammation, improve metabolic health, and lower cardiovascular risk at its source Heart disease isn't simply a cholesterol problem—it's often a metabolic and inflammatory problem. When you understand what's really driving your risk, you can stop chasing a single number and start addressing the underlying biology that supports lifelong cardiovascular health. Track your metabolic and cardiovascular health biomarkers: functionhealth.com/mark for 160+ lab tests at just $365/year. Use code MARK2026 for $50 off. Have a question you'd love answered on Office Hours? Submit it here' (0:00) The cholesterol and heart disease paradox; introduction and overview of cholesterol, inflammation, and metabolic health (1:11) Sponsor: Function Health (1:41) Traditional views vs. new science on cholesterol, inflammation, and heart disease (4:52) Inflammation and sugar as key factors in heart disease (8:41) Advanced markers: ApoB, lipoprotein fractionation, and comprehensive testing (13:57) Causes of inflammation and holistic heart disease prevention (19:35) Metabolic health risks, new technologies, and personalized interventions (22:35) Diet, exercise, lifestyle, and supplements for heart and metabolic health (25:03) Understanding heart disease beyond cholesterol (25:37) Sponsor: Brain Shaping Academy (26:33) Community engagement, sharing, and final thoughts (28:07) Sponsor acknowledgments and closing remarks