Podcasts about metabolic

In this biochemistry-made-simple episode, Dr. Scott Watier and Tommy Welling use the powerful "metabolic battery" analogy to explain why some people feel stuck despite doing everything right with their fasting and food choices. They break down how excess glucose creates a traffic jam in your mitochondria by overloading NADH and depleting NAD+, which promotes insulin resistance and blocks fat burning even when you're following your fasting schedule perfectly. The hosts reveal why reaching for NAD+ supplements misses the point—it's like adding more battery packs to a device you never unplug—and instead provide actionable strategies to restore natural battery cycling through consistent fasting windows, protein-based meals, post-meal movement, and protected sleep. They explain how continuous glucose monitors show you the real-time movie of your metabolic battery's charge-discharge cycle, not just the final score like A1C tests, helping you understand why certain food choices create the wired-and-tired, crashing-after-meals pattern that sabotages your fasting efforts and keeps you trapped in a cycle of cravings and inconsistent results. ⁠⁠⁠⁠⁠Take the NEW FASTING PERSONA QUIZ! - The Key to Unlocking Sustainable Weight Loss With Fasting!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Resources and Downloads: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠SIGN UP FOR THE DROP OF THE ULTIMATE GUIDE TO BLOOD SUGAR CONTROL⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠GRAB THE OPTIMAL RANGES FOR LAB WORK HERE! - NEW RESOURCE! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠FREE RESOURCE - DOWNLOAD THE NEW BLUEPRINT TO FASTING FOR FAT LOSS!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠SLEEP GUIDE DIRECT DOWNLOAD⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠DOWNLOAD THE FASTING TRANSFORMATION JOURNAL HERE!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Partner Links: Get your⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ FREE BOX OF LMNT⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ here!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Get ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠25% off a Keto-Mojo⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ blood glucose and ketone monitor (discount shown at checkout)! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Click here!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Our Community: Let's continue the conversation. Click the link below to JOIN the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Fasting For Life Community⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply! If you enjoy the podcast, please tap the stars below and consider leaving a short review on Apple Podcasts/iTunes. It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them! Article Links: https://www.youtube.com/watch?v=7gN0hEyCO_E

Every year, the clock change brings more than just a few days of fatigue. This episode uncovers the profound physiological impact of Daylight Savings Time, particularly the spring shift, on your health. Moving beyond anecdotal complaints, we delve into the published research revealing population-scale circadian disruption and its downstream effects. This is your ultimate guide to understanding the hidden dangers of Daylight Savings and how to prepare yourself and your clients to navigate the clock change with minimal impact on your heart, brain, and metabolic health. Topics discussed:- Circadian disruption- Spring shift risks- Physiological mechanisms- Metabolic dysregulation- Proactive strategies- Coaching opportunities---------- ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠My Live Program for Coaches: The Functional Nutrition and Metabolism Specialization ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.metabolismschool.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠---------- [Free] Metabolism School 101: The Video Series⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://www.metabolismschool.com/metabolism-101⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠----------Subscribe to My Youtube Channel: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://youtube.com/@sammillerscience?si=s1jcR6Im4GDHbw_1⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠----------⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Grab a Copy of My New Book - Metabolism Made Simple⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠---------- Stay Connected: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram: @sammillerscience⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Youtube: SamMillerScience⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook: The Nutrition Coaching Collaborative Community⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TikTok: @sammillerscience⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠----------“This Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast and the show notes or the reliance on the information provided is to be done at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment and is for educational purposes only. Always consult your physician before beginning any exercise program and users should not disregard, or delay in obtaining, medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. By accessing this Podcast, the listener acknowledges that the entire contents and design of this Podcast, are the property of Oracle Athletic Science LLC, or used by Oracle Athletic Science LLC with permission, and are protected under U.S. and international copyright and trademark laws. Except as otherwise provided herein, users of this Podcast may save and use information contained in the Podcast only for personal or other non-commercial, educational purposes. No other use, including, without limitation, reproduction, retransmission or editing, of this Podcast may be made without the prior written permission of Oracle Athletic Science LLC, which may be requested by contacting the Oracle Athletic Science LLC by email at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠operations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@sammillerscience.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. By accessing this Podcast, the listener acknowledges that Oracle Athletic Science LLC makes no warranty, guarantee, or representation as to the accuracy or sufficiency of the information featured in this Podcast."

In this episode, fertility expert Gabriela Rosa reveals one of the biggest blind spots in modern fertility care: many couples are pushed toward treatments like IVF before receiving a true diagnosis. She breaks down how fertility clinics often operate, why infertility is frequently misunderstood, and how underlying issues such as thyroid dysfunction, insulin resistance, and PCOS can significantly impact reproductive outcomes. Gabriela shares powerful patient stories, including Renee's own experience, to illustrate how personalized investigation and root-cause medicine can dramatically shift fertility trajectories. She also explains why fertility is a “team sport,” outlining her strategic approach to improving egg quality, hormonal balance, and metabolic health while interpreting key tests like AMH and follicle development timelines. The conversation concludes with practical guidance on nutrition's role in fertility, her “Three Rocks” framework for treatment, and a thoughtful decision tree to help women determine when egg freezing may or may not be the right choice. Gabriela Rosa, DrPH (Candidate, Harvard), is a Harvard-awarded fertility specialist, founder of The Rosa Institute, and author of Fertility Breakthrough: Overcoming Infertility and Recurrent Miscarriage When Other Treatments Have Failed. She pioneered telehealth-based, integrative fertility care, making evidence-based solutions accessible worldwide.Gabriela also created and hosts The Fertility Challenge, a free online program that reaches tens of thousands globally each year. Her F.E.R.T.I.L.E. Method® has supported more than 204,000 people across 111 countries, with published research demonstrating a 78.8% live birth rate among patients in her signature program—even after years of infertility, recurrent miscarriage, and failed treatments.SHOW NOTES:0:39 Welcome to the show!2:43 About Gabriela Rosa3:35 Welcome her to the podcast!4:47 The biggest blindspot in fertility9:05 How fertility clinics operate10:56 What does infertility mean?11:52 Getting a proper diagnosis12:36 Patient story16:26 IVF industry goals18:48 Miscarriage & Thyroid21:19 Renee's story23:35 IUI incentives & results25:19 Who benefits from IVF?27:50 *APOLLO NEURO*29:50 *CALOCURB*31:00 Who gets turned away from her clinic35:39 Who she does work with37:30 Fertility is a team sport40:05 Her strategy for improving fertility43:16 Timeline of eggs & follicles45:45 AMH testing & optimal ranges51:14 PCOS & Insulin Resistance55:04 Infertility and all-cause mortality1:01:03 Research on correlation between nutrition & fertility1:05:38 The 3 Rocks1:11:09 Egg Freezing decision treeRESOURCES:Apollo Neuro - code: BIOHACKERBABES for $90 offCalocurb - code: RENEE10Website: fertilitybreakthrough.comIG: @dr.gabrielarosa, @fertilitybreakthroughFB: FertilitySpecialistGabrielaRosaX: gabrielarosaTikTok: @gabrielarosafertilityPodcast: Talk Sex with Gabriela RosaSupport this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands

If you're on Wegovy, Zepbound, Ozempic, or Mounjaro — and worried about what happens when you stop — this episode is for you. The fear of gaining it all back is real. But weight regain is not inevitable. It's manageable. And I'm going to show you how. "What happens when you stop your GLP-1?" This is one of the most common questions I get in my clinic every single week. It's time I answered it publicly — with science, not fear. In this episode, I break down exactly what happens in your body when you stop your GLP-1, why weight regain happens, and the five pillars you need to protect your results, whether you're stopping by choice or out of necessity. Listen now! Episode Highlights: The physiological reason hunger surges and metabolism slows when you stop GLP-1s  What the SURMOUNT-4 clinical trial tells us about weight regain after stopping Tirzepatide Who is at highest risk for regaining weight  The 5 pillars of weight maintenance: protein, resistance training, carb awareness, appetite retraining, and medication transition strategy Connect with Dr. Alicia Shelly: Website | drshellymd.com Facebook | www.facebook.com/drshellymd Instagram | @drshellymd Linked In | www.linkedin.com/in/drshellymd Twitter | @drshellymd About Dr. Alicia Shelly Dr. Alicia Shelly was raised in Atlanta, GA. She received her Doctorate of Medicine from Case Western Reserve University School of Medicine in Cleveland, OH.  Dr. Shelly has been practicing Primary Care and Obesity medicine since 2014.  In 2017, she became a Diplomat of the American Board of Obesity Medicine. She is the lead physician at the Wellstar Medical Center Douglasville. She started a weekly podcast & Youtube channel entitled Back on Track: Achieving Healthy Weight loss,  where she discusses how to get on track and stay on track with your weight loss journey. She has spoken for numerous local and national organizations, including the Obesity Medicine Association, and the Georgia Chapter of the American Society of Metabolic and Bariatric Surgeons. She has been featured on CNN, Fox 5 News, Bruce St. James Radio show, Upscale magazine, and Shape.com. She was named an honoree of the 2021 Atlanta Business Chronicle's 40 under 40 award. She also is a collaborating author for the, "Made for More: Physician Entrepreneurs who Live Life and Practice Medicine on their own terms''. Resources: FREE! Discover the 5 Reasons Your Weight-Loss Journey Has Gotten Derailed (And How To Get Back On Track!)

He explains how sugar, especially fructose and fruit, fuels cancer—drawing on 40 years of data and research from Thomas Seyfried. #SugarAndCancer #MetabolicDisease #HealthTalks

Send a textMitochondria in human evolution, climate adaptation, maternal genetics, aging, and disease.TOPICS DISCUSSED:Endosymbiotic theory: Mitochondria arose from oxidative bacteria engulfed by archaea-like hosts, confirmed by phylogenetic analysis.Maternal mtDNA inheritance: Mitochondrial DNA is inherited from the mother, not the father. There are adaptive reasons for this.Haplogroups & adaptation: Tropical lineages tightly couple energy production for efficiency; northern ones uncouple to generate heat.Heteroplasmy & aging: Mixed mutant and normal mitochondria accumulate in cells, eroding energy in high-demand tissues like brain and heart.Bioenergetics in disease: Many common conditions, from Parkinson's to cancer, stem from mitochondrial-nuclear interactions rather than nuclear genes alone.Ketogenic diets: High-fat intake fuels mitochondrial beta-oxidation, which may compensate for brain energy deficits in epilepsy and bipolar disorder.Warburg effect: Cancer cells shift to glycolysis to prioritize biosynthetic building blocks over maximal ATP production.Modern mismatches: Global travel pairs ancestral mtDNA with mismatched diets and climates, raising risks for metabolic dysfunction.ABOUT THE GUEST: Douglas Wallace, PhD is a geneticist and evolutionary biologist who has studied mitochondria for over 50 years. He currently directs the Center for Mitochondrial and Epigenomic Medicine at Children's Hospital of Philadelphia and the University of Pennsylvania.RELATED EPISODE:M&M 260 | Energy Resistance Principle in Life, Healing & Disease | Martin Picard & Nirosha MuruganSupport the showHealth Products by M&M Partners: SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off. Lumen device: Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts

A patient with metabolic disease develops progressive shoulder pain with loss of motion, proximal thigh weakness, and has a history of low‑trauma fractures. The physical exam shows periarticular tenderness and visible muscle atrophy.  The patient also reports the muscular weakness is worsened at the end of each day. Which of the following conditions is MOST likely present? Find it all out in the podcast! Be prepared for the NPTE so that you can pass with flying colors! Check out www.ptfinalexam.com/podcast for more information and to stay up-to-date with our latest courses and projects. #Npte #PT #ptboards #crushtheNPTE #study #studygram #spt #ptstudent #ptlife #sptprobs #physicaltherapystudent #physicaltherapy #physio #physiotherapist #ptlife #ptstudentstudy

Reverse dieting has been a buzzword in fitness for years, promising a way to increase calories without gaining fat. But why do so many coaches and individuals still get it wrong? This episode dives deep into the 5 crucial mistakes that can derail your reverse diet, turning a promising strategy into a frustrating setback. Topics discussed: - Individual factors- Importance of adherence - Impact of gut issues on digestion and bloat- Metabolic adaptation- Nuance in approach for athletes vs. general population---------- ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠My Live Program for Coaches: The Functional Nutrition and Metabolism Specialization ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.metabolismschool.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠---------- [Free] Metabolism School 101: The Video Series⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://www.metabolismschool.com/metabolism-101⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠----------Subscribe to My Youtube Channel: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://youtube.com/@sammillerscience?si=s1jcR6Im4GDHbw_1⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠----------⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Grab a Copy of My New Book - Metabolism Made Simple⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠---------- Stay Connected: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram: @sammillerscience⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Youtube: SamMillerScience⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook: The Nutrition Coaching Collaborative Community⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TikTok: @sammillerscience⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠----------“This Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast and the show notes or the reliance on the information provided is to be done at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment and is for educational purposes only. Always consult your physician before beginning any exercise program and users should not disregard, or delay in obtaining, medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. By accessing this Podcast, the listener acknowledges that the entire contents and design of this Podcast, are the property of Oracle Athletic Science LLC, or used by Oracle Athletic Science LLC with permission, and are protected under U.S. and international copyright and trademark laws. Except as otherwise provided herein, users of this Podcast may save and use information contained in the Podcast only for personal or other non-commercial, educational purposes. No other use, including, without limitation, reproduction, retransmission or editing, of this Podcast may be made without the prior written permission of Oracle Athletic Science LLC, which may be requested by contacting the Oracle Athletic Science LLC by email at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠operations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@sammillerscience.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. By accessing this Podcast, the listener acknowledges that Oracle Athletic Science LLC makes no warranty, guarantee, or representation as to the accuracy or sufficiency of the information featured in this Podcast."

referencesCell Death & Disease 2026. 17, Article number: 71 Am J Physiol Cell Physiol. 2020 Dec 9;320(3):C415–C427Guerra, DJ.2026. Unpublished LecturesJagger/Richards. 1964. As Tears Go By. Marrianne Faithful https://open.spotify.com/track/2EYXCRp63iQdmeKHXN8Rrg?si=70ceced5d9304eb8Mozart , WA 1779. Sinfonia Concertante in E flat Major K.364https://music.youtube.com/watch?v=_0hTDZ0whpU&si=NNbjswoPokVPveuu

Get free access to our new Ketogenic Metabolic Therapy ebook here.Could changing your metabolism reduce alcohol cravings, ease psychiatric symptoms, and even make cancer immunotherapy more effective? The science is pointing to yes, and the mechanisms are fascinating.In this Journal Club episode, co-hosts Victoria Field, Dr. Dominic D'Agostino, and Dr. Angela Poff break down five peer-reviewed papers from their newly released Ketogenic Metabolic Therapy ebook (Volume 4). From a French preclinical study showing ketogenic diet enhances PD-L1 immunotherapy response in kidney cancer, to an NIH/UPenn trial using machine-learning-derived fMRI signatures to measure reduced alcohol cravings during ketosis, to Stanford's pilot trial demonstrating notable metabolic and psychiatric improvements in schizophrenia and bipolar disorder, this episode covers the cutting edge of metabolic therapy research.Questions Answered in This Episode:Why does the brain crave alcohol in people with alcohol use disorder, and how might ketones help? How might a ketogenic diet affect a tumor's response to immunotherapy?Can insulin resistance in the brain contribute to psychiatric symptom severity?How does the ketogenic diet compare to the Mediterranean diet for autoimmune inflammation?Does timing of ketogenic diet initiation matter for chronic pain relief?Is it realistic for people with serious mental illness to adhere to a ketogenic diet?Whether you're a clinician, researcher, or someone looking to understand the latest science, this episode reveals just how far-reaching ketogenic metabolic therapy has become, spanning oncology, psychiatry, addiction, autoimmune disease, chronic pain, and much more!In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

In this episode of Keeping Abreast, Dr. Jenn Simmons is joined by Jen Nolan and Sara Stratton of Remission Nutrition for a conversation that cuts through the noise around “healthy living” after a breast cancer diagnosis.Jen explains how nutrigenomics (genetic-based nutrition + lifestyle guidance) helps women understand what their body actually needs, from detox capacity to fat metabolism to exercise tolerance. Dr. Jenn shares her own example: years of high-intensity endurance workouts that she thought were helping until genetic testing revealed they were doing real harm.Sara shares her story of being diagnosed with stage 3C triple positive breast cancer at 37, and how she supported her body through chemotherapy and recovery using a metabolic approach, including fasting around treatment, strength training, mindfulness, and carefully chosen supplements. Together, they talk about how to make changes without overwhelm, avoid fear-based restriction and orthorexia, navigate resistance from conventional providers, and build a lifestyle that's sustainable long-term - with joy included.In This Episode, You'll Learn:What nutrigenomics can tell you about food, detox, sleep, stress, and exerciseSara's approach to supporting her body during chemo: fasting, movement, mindfulness, and recoveryWhat to know about supplements during chemotherapy including why antioxidants can be trickyWhy people get overwhelmed after diagnosis, and how to start with small, realistic stepsThe “crowding out” method: what to add first so healthy habits stickCommon non-negotiables that move the needle fast (Diet soda + processed snack foods)How to avoid orthorexia and stop turning food into fearHow to advocate for yourself when your oncologist dismisses integrative toolsEpisode Timeline: 01:06 Introducing Jen Nolan + Sara Stratton 04:10 Nutrigenomics and personalized healing 10:56 Sara's diagnosis at 37 + what life looked like before 13:55 Metabolic approach during treatment (fasting, keto, movement) 24:14 Fasting around chemo + how she trained through treatment 28:47 Supplements + what to avoid during chemotherapy 32:11 Fat metabolism genes + why keto doesn't work the same for everyone 35:59 How to start without overwhelm (3 changes at a time) 44:44 Treatment phase vs. long-term lifestyle (graduating from strictness) 49:55 Why conventional providers resist integrative support 51:43 What to do when your oncologist dismisses fasting/nutrition 54:34 Why breast cancer is usually not an emergency (and time matters) 58:48 Joy, purpose, and living while healingTo talk to a member of Dr. Jenn's team and learn more about working privately with Dr. Jenn visit: https://calendly.com/stephanie-1031/clarity-callTo get your copy of Dr. Jenn's book, The Smart Woman's Guide to Breast Cancer, visit: https://tinyurl.com/SmartWomansBreastCancerGuideTo purchase the auria breast cancer screening test go here https://auria.care/ and use the code DRJENN20 for 20% Off.Connect with Dr. Jenn:Website: https://www.jennsimmonsmd.com/Facebook: https://www.facebook.com/DrJennSimmonsInstagram: https://www.instagram.com/drjennsimmons/YouTube: https://www.youtube.com/@dr.jennsimmons

ReferencesGuerra, DJ. 2026. Unpublished LecturesScience Translational Medicine 2019: 17 Jul. Vol. 11, Issue 501, eaav7816Lennon/McCartney. 1969. Let it Be Beatleshttps://open.spotify.com/track/7iN1s7xHE4ifF5povM6A48?si=77799fa1a6ca494e

ReferencesGuerra, DJ. 2026 Unpublished LecturesCell.2022 Jun 16;185(14):2542–2558.e18. https://omim.org/entry/607358Experimental & Molecular Medicine2025 57:1881–1892Hunter/Garcia, 1968. Dark Star Grateful Dead Live/Dead LP https://open.spotify.com/track/07CwWCJetytT1cSnQOgRMU?si=de8e173488834efb

GLP-1 medications are either wildly overhyped or harshly criticized depending on the week—and one of the loudest concerns right now is that they “cause muscle loss.” In this episode, I'm digging into what the research actually shows about lean mass changes on GLP-1s, what's being misunderstood online, and what patients and clinicians can do to protect muscle while still benefiting from these powerful therapies. To help me unpack this, I'm joined by Dr. Michael Tsoukas, Associate Professor of Medicine in the Division of Endocrinology at the McGill University Health Centre, Co-Director of the Metabolic & Weight Optimization Clinic, and a clinician-scientist whose work focuses on GLP-1 pharmacotherapy and obesity treatment. He's trained at Tufts, McGill, and Harvard, and has authored over 50 peer-reviewed publications.We talk about where the muscle-loss concern came from, how GLP-1 weight loss compares to bariatric surgery and diet-only approaches, and whether lean mass loss always reflects true functional muscle loss. We also get practical, discussing resistance training and protein targets (it's more than you may think!).If you're on a GLP-1, considering one, or prescribing them—this is a science-based conversation that separates fear from facts.Guest: Dr. Michael TsoukasWebsite: mwoc.caWORK WITH MEJoin my Weight Loss Coaching Program for women, Best Weight https://www.sashahighmd.com/bestweightRecover Strong for Binge Eatinghttps://www.sashahighmd.com/bedO​​ntario-Wide Virtual Obesity Management Clinichttps://www.highmetabolicclinic.comTaking the first step toward weight loss can feel overwhelming — but you don't have to do it alone. I've created a curated list of my podcast episodes to gently guide you as you begin your journey. https://www.sashahighmd.com/podcast-guideFOLLOW SASHAInstagramhttps://www.instagram.com/sashahighmd/

Cheap food holds capitalism together. But to get it, we've had to cheapen almost everything on the planet: the work of women, nature and colonies. We've made strange new ecologies all over the world, and now we're living in the metabolic sh*tshow. How will the ruling class keep control? On this week's Do Your Own Research, […]

ReferencesImmun Ageing. 2020; 17: 2.Trends in Immunology. 2017. REVIEW| VOLUME 38,ISSUE 4, P287-297, APRIL 01, Int J Mol Sci. 2025 Apr 27;26(9):4147Experimental & Molecular Medicine 2019. volume 51, Article number: 80 Beethoven, LV 1811. Piano Concert V in E Flat Major OP 73.https://music.youtube.com/watch?v=q-hn8WH_-3U&si=TNpna_2DZLIoX2nM

What if your anxiety, brain fog, or mood swings aren't psychological flaws—but signs of a brain energy crisis? In this episode, we explore Metabolic Psychiatry, insulin resistance, mitochondrial health, and the emerging science behind brain energy metabolism. You'll learn how Metabolic Synchronization—aligning blood sugar, lean muscle mass, and mitochondrial function—may be the missing link to mental clarity, cognitive resilience, and long-term life control. If the brain is an energy system, then reclaiming your mental agency begins with metabolic repair. Let's make sense of it. #MetabolicPsychiatry #BrainEnergy #MentalHealth2026 #InsulinResistance #MitochondrialHealth Follow Dr. JC Doornick and the Makes Sense Academy:► Makes Sense Substack - https://drjcdoornick.substack.com ► Instagram: / drjcdoornick ► Substack: / drjcdoornick ►Facebook:  / makessensepodcast ►YouTube:  / drjcdoornick MAKES SENSE PODCAST Welcome to the Makes Sense with Dr. JC Doornick Podcast. This podcast explores topics that expand human consciousness and enhance performance. On the Makes Sense Podcast, we acknowledge that it's who you are that determines how well what you do works, and that perception is subjective and an acquired taste. When you change the way you look at things, the things you look at begin to change. Welcome to the uprising of the sleepwalking masses. Welcome to the Makes Sense with Dr. JC Doornick Podcast. SUBSCRIBE/RATE/REVIEW & SHARE our new podcast. FOLLOW Podcast: You will find a "Follow" button in the top right. This will enable the podcast software to alert you when a new episode launches each week. Apple: https://podcasts.apple.com/ca/podcast/makes-sense-with-dr-jc-doornick/id1730954168 Spotify: https://open.spotify.com/show/1WHfKWDDReMtrGFz4kkZs9?si=003780ca147c4aec Podcast Affiliates: Kwik Learning: Many people ask me where I get all these topics, which I've been covering for almost 15 years. I have learned to read nearly four times faster and retain information 10 times better with Kwik Learning. Learn how to learn and earn with Jim Kwik. Get his program at a special discount here: https://jimkwik.com/dragon OUR SPONSORS: Makes Sense Academy: A private mastermind and psychologically safe environment full of the Mindset and Action steps that will help you begin to thrive. The Makes Sense Academy. https://www.skool.com/makes-sense-academy/about The Sati Experience: A retreat designed for the married couple that truly loves one another, yet wants to take their love to that higher magical level. Relax, reestablish, and renew your love at the Sati Experience. https://www.satiexperience.com Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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This week I interviewed Reed Davis for the second time! Reed Davis is a Board Certified Holistic Health Practitioner(HHP) and Certified Nutritional Therapist (CNT), is an expert in functional lab testing and holistic lifestylemedicine. He is the Founder of Functional Diagnostic Nutrition (FDN) and the FDN Certification Course with over 4,000 graduates in 50 countries. We discussed how to avoid environmental toxins, the new food pyramid, Reed's top health principals and his one tip to get your body back to what it once was! Connect with Reed: https://www.functionaldiagnosticnutrition.com/“FDN Methodology in Action” case study series at https://www.fdntraining.com/eatclean26--------How to Take Simple Steps to Reclaim the Body, Energy, and Strength You Had 10-15 Years Ago Using My Stepladder System:https://www.stepladdersystem.com/FREE Nutrition Cheatsheets:https://brian-getleaneatclean.beehiiv.com/subscribeClick to book a FREE 15 minute consult with Brian:https://calendly.com/bdgryn/15min------------Interested in Upgrading your Mitochondria, Improving Energy and Sleep! Check out Troscriptions: https://bit.ly/4ik5kK5Use Discount Code for 10% OFF: EATCLEAN----Watch Get Lean Eat Clean podcast video episodes on YouTube!YouTube.com/@briangryn3680----B.rad Whey Protein Isolate Superfuel:The Best Protein on The Planet! Available in Two Delicious Flavors: Vanilla Bean and Cocoa BeanUse Coupon Code glec10off for 10% off your order!https://a.co/d/731gssV----My favorite health bars with clean ingredients!https://www.eatprima.com/BRIAN6816310% OFF with this link!

Show Notes HOST Melody Hartzler | | Book Appointment AROUND THE TABLE Kara Siedman | ResBiotic In Today's Episode In this episode of the Tables Talk Podcast, Dr. Melody Hartzler sits down with Kara Siedman, RD, CDCES, Director of Partnerships at ResBiotic, to examine how microbiome-driven physiology intersects with hormonal transitions during perimenopause and menopause. As estrogen and progesterone fluctuate and decline, women experience predictable shifts in metabolic regulation, immune signaling, and inflammatory burden. Increasing evidence suggests these changes are tightly linked to alterations in gut microbial diversity, intestinal barrier integrity, and microbial metabolite production. This conversation explores the gut–hormone axis through a mechanistic lens, highlighting how microbiome dysfunction may amplify symptoms such as blood sugar instability, weight gain, estrogen dominance, gastrointestinal distress, and genitourinary changes. Kara draws on clinical experience and emerging research to clarify why many hormonally driven symptoms occur in the absence of overt disease on conventional testing. The episode emphasizes perimenopause as a critical intervention window—one in which targeted dietary, lifestyle, and microbiome-supportive strategies may meaningfully influence long-term cardiometabolic and immune health. Key Takeaways Hormonal decline during perimenopause is closely linked to reduced microbiome diversity and resilience Estrogen loss impacts intestinal barrier function, inflammation, and metabolic regulation The estrobolome plays a central role in estrogen metabolism and symptom expression Microbiome-targeted interventions may reduce cardiometabolic risk during menopause Diet, fiber diversity, and precision biotics are foundational tools for supporting this transition Episode Highlights Hormonal Transitions & the Gut–Hormone Axis Estrogen and progesterone fluctuations in perimenopause Bidirectional signaling between endocrine function and the microbiome Declining microbial diversity and reduced short-chain fatty acid production Inflammation, Metabolism, and Insulin Resistance Metabolic endotoxemia and LPS-driven inflammation Microbiome contributions to blood sugar dysregulation and weight gain Links between dysbiosis, immune activation, and chronic disease risk The Estrobolome & Estrogen Metabolism Beta-glucuronidase activity and estrogen deconjugation Microbial reactivation of estrogen and clinical implications Estrogen dominance, elimination pathways, and gut health Vaginal Microbiome & Genitourinary Health Estrogen-dependent Lactobacillus depletion Increased risk of UTIs and yeast infections Gut–vaginal microbiome crosstalk and clinical considerations Clinical Interventions to Support Microbiome Resilience Mediterranean-style dietary patterns and plant diversity Fiber intake, resistant starch, prebiotics, probiotics, and postbiotics Stress, sleep disruption, medications, and microbiome vulnerability Precision supplementation during the menopausal transition

Best Of 2GG: Brooke at Metabolic (use your words wisely) by Two Girls and a Guy

ReferencesSCIENTIFIC REPORTS 2016 | 6:34594 | DOI:10.1038/srep34594 Seminars in Immunology 2025. V. 78,Jun, 101954Front Immunol. 2025 Jan 8:15:1515715Telemann, GP. 1735. Sinfonia Spirituosa TWV 40&50https://open.spotify.com/album/2nJX3LIjdAbNIGR3qbQaBI?si=VF-7aHcBS_qOkEsl34LdKQ

In this powerful episode, we sit down with Dr. Joe Zundell — aka “Cancer Daddy” — for a wide-ranging conversation on cancer science, early detection, and what's actually moving the field forward. We cover: • Multi-cancer early detection (MCED) testing and the promise of liquid biopsies • Accuracy, limitations, and clinical decision-making • Metabolic vulnerabilities in cancer (Warburg effect, glutamine dependence) • Epigenetics and tumor biology • Immunotherapy, targeted therapies, and radiopharmaceuticals • Translational research and the bench-to-bedside gap • Drug resistance and evolutionary pressure in cancer treatment • Personalized risk reduction and prevention strategies We also get very personal in this episode — discussing loss, integrity in academia, career pivots, and what truly drives Dr. Zundell's mission in cancer research. This is an honest, science-first, and deeply human conversation about cancer, prevention, innovation, and responsibility in modern medicine. Coach Vinny Email: vinny@balancedbodies.io Instagram: vinnyrusso_balancedbodies Facebook: Vinny Russo Dr. Eryn Email: dr.eryn@balancedbodies.io Instagram: dr.eryn_balancedbodies Facebook: Eryn Stansfield Dr. Joe Zundell Email: drjoezundell@gmail.com Instagram: dr.joezundell LEGION 20% OFF CODE Go to https://legionathletics.com/ and use the code RUSSO for 20% off your order!

ReferencesAntimicrob Agents Chemother. 2017 Dec 21;62(1):e01614-17Br J Cancer. 2002 Mar 18;86(6):963–970Science Translational Medicine 2019: vol. 11, Issue 501, 17 Jul Int J Mol Sci. 2025 Apr 27;26(9):4147 Fogerty, J 1969. Fortunate Son. CCRhttps://open.spotify.com/track/4BP3uh0hFLFRb5cjsgLqDh?si=5b6bd7dea0774f9dHunter/Garcia. 1973 It Must Have Been the Roses. Grateful Dead [Reckoning] lphttps://music.youtube.com/watch?v=tvXQ7r-n-Go&si=J6mTP9rquTHkNo-D

Why does losing weight feel so much harder after 40? If you found it easy to lose weight and build muscle in your 30s, but now those same strategies barely make an impact, you're not imagining things. Your body is following a new set of rules. In this episode, we break down what happens to your hormones, your metabolism, and your muscle mass as you age, and, more importantly, what you can do about it. We explore everything from GLP-1 medications and peptide therapies to creatine, protein targets, and why resistance training is non-negotiable for maintaining weight loss. Whether you're just starting your weight loss journey or you've hit a frustrating plateau, this episode will help you understand what's happening in your body and what to do next. How to Maintain Muscle Mass While Losing Weight Do resistance training 2–3 times per week Eat about 100 grams of protein per day  Take 3–5 grams of creatine daily Ensure you are properly hydrated- aim for 100 ounces per day Use peptides  Consider targeted therapies Track your body composition instead of using the scale Bio: Stephanie Gray Stephanie Gray, DNP, MS, ARNP, AGNP-C, ABAAHP, FAARFM, is a functional medicine provider who helps men and women build sustainable, optimal health and longevity.  A nurse practitioner since 2009, Dr. Gray completed her doctorate focusing on estrogen metabolism from the University of Iowa in 2011 and holds a Master's in Metabolic Nutritional Medicine from the University of South Florida's Medical School. Dr. Gray is one of the Midwest's most credentialed female healthcare providers. She completed an Advanced Fellowship in Anti-Aging, Regenerative, and Functional Medicine in 2013 and became Iowa's first BioTe certified provider—now the state's only platinum provider with over 10,000 pellet placements. She is also certified as a SIBO doctor-approved practitioner, mold-literate provider, and ReCODE 2.0 practitioner for cognitive decline prevention. An Amazon best-selling author, Dr. Gray wrote Your Longevity Blueprint and Your Fertility Blueprint, and hosts the Your Longevity Blueprint podcast. She co-founded Your Longevity Blueprint Nutraceuticals with her husband, Eric. After her own ten-year fertility journey, she now specializes in helping couples optimize reproductive health through functional medicine. Having lost her grandmother to vascular dementia, she is personally committed to helping families avoid cognitive decline. Dr. Gray founded the Integrative Health and Hormone Clinic in Hiawatha, Iowa. In this episode: Why your weight loss strategy will need to change in your forties Why optimizing your hormones should be foundational to your weight loss strategy How resistance training helps to preserve your muscle mass when you're taking GLP-1s The benefits of creatine and peptides for women over 40 How the Emsculpt Neo can help with fat reduction The value of tracking your protein intake Why proper hydration is crucial for your muscles, metabolism, and regulating stress Links and Resources: Guest Social Media Links: @stephaniegraydnp Relative Links for This Show:  ⁠⁠⁠⁠⁠⁠Use Code FIBER to get 10% off GLP-1 Fiber⁠ ⁠⁠⁠⁠⁠Use code CREATINE to get 10% off Creatine Use code Drgray20 to get 20% off ⁠Perfect Aminos Follow Your Longevity Blueprint  On Instagram| Facebook| Twitter| YouTube | LinkedIn Get your copy of the Your Longevity Blueprint book and claim your bonuses here Find Dr. Stephanie Gray and Your Longevity Blueprint online   Follow Dr. Stephanie Gray  On Facebook| Instagram| Youtube | Twitter | LinkedIn Integrative Health and Hormone Clinic Podcast production by Team Podcast

In this episode of The Health Fix Podcast, Jay Campbell, best known for being the testosterone replacement therapy guru shares his two-decade plus journey into the world of peptides and hormone replacement therapy and how these compounds have transformed not just physique and fat loss, but metabolic health and longevity.  This conversation goes far beyond weight loss headlines and dives into the mental benefit side of health optimization. **We get real in this episode and there's some swear words so if you're listening with kiddos around listen with caution** What You'll Learn In This Episode: Why GLP peptides are reshaping obesity treatment The power of microdosing peptides, especially GLP-1's, for sustainable results Why education is the missing link for both clinicians and patients Injectable vs oral peptides — what actually works The role of lifestyle optimization alongside peptide therapy How misinformation (and AI amplification) is distorting public perception The humanitarian mission to make peptide therapies more accessible Peptides Are a Tool — Not a Shortcut Jay emphasizes that GLP peptides can dramatically improve metabolic health but without lifestyle changes, long-term success is limited. For those who want to stay active and adventure-ready, peptides may: Improve insulin sensitivity Reduce inflammation Support fat loss Enhance recovery But they are meant to amplify effort, not replace it.   Microdosing Changes the Game One of the most powerful strategies discussed is microdosing. Rather than high-dose protocols aimed purely at appetite suppression, strategic lower dosing can: Preserve muscle mass Reduce side effects Improve metabolic flexibility Support long-term sustainability This is particularly important for athletic or active adults who don't want to lose performance while improving body composition.   Injectable > Oral Jay explains why injectable peptides remain the gold standard due to bioavailability and effectiveness. Understanding delivery method matters especially for those investing in advanced health strategies.   The Future of Obesity Treatment We're entering an era where next-generation GLP and triple-agonist peptides are transforming how we address: Insulin resistance Chronic inflammation Fat loss resistance Metabolic disease But access, education, and responsible use are critical and why Jay and I do podcasts like this!   Health Optimization as a Spiritual Practice One of the most compelling parts of the conversation: When you optimize your biology, you elevate your capacity; physically, mentally, and spiritually. Health isn't vanity. It's vitality. It's freedom. It's staying in the game.   Resources From The Show: Jay's Website - https://jaycampbell.com/ Jay's Peptide Company - https://biolongevitylabs.com/ Jay's New Book - Metabolic Awakening with GLP-1 Peptides Dr. J's March 18th, 2026 Workshop: 5:30p PST/7:30p CST (register to get the replay if you can't make it live) - The Art of Staying Your Sport or Hobby and Being Adventure Ready at Any Age    

Send a textDr. Gagandeep Singh joins Dr. Michael Koren to discuss his triangle approach, which combines the talents of a medical doctor, a nutritionist, and a trainer to tackle the medications, diets, and exercise changes needed to make a difference in metabolic diseases. Metabolic diseases include diabetes, hypertension, obesity, and polycystic ovary syndrome (PCOS). Dr. Singh, who practices in India, explains how this holistic approach has resulted in high success rates, with patients improving their lab numbers, losing weight, and reducing their medications as he "treats to success."Be a part of advancing science by participating in clinical research.Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.comListen on SpotifyListen on Apple PodcastsWatch on YouTubeShare with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramX (Formerly Twitter)LinkedInWant to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.comMusic: Storyblocks - Corporate InspiredThank you for listening!

ReferencesFront Immunol. 2015 Sep 28;6:493Guerra, DJ. Unpublished LecturesInt J Mol Sci. 2025 Apr 27;26(9):4147Biomolecules2019, 9(10), 513Vivaldi, A. 1715. The Great Venetian Masshttps://music.youtube.com/playlist?list=OLAK5uy_nz3Iy2f-mkA2jbas2npilpkSh3Db5l-wY&si=DesZSQv0ZBZcvrw-

Are WiFi, blue light, and modern tech quietly frying your mitochondria?Occupational Therapist (and championship Pole Dancer!) Kristen Gilbert joins me to break down quantum biology in a way that actually makes sense — from metabolic water (Gerald Pollack's “fourth phase water”) to circadian light signaling, grounding, EMF mitigation, and how sunrise might be the most underrated healing practice on Earth.We also explore sacred geometry, honeycomb lattice water, tattoos as energetic transmission, and how tending to your mitochondrial terrain can radically shift mood, energy, and resilience.This conversation bridges science, mysticism, and lived experience in a way that will change how you think about your body.Watch on Odysee. Listen on podcast platforms everywhere.Part 2:danikatz.locals.comwww.patreon.com/danikatz All things Dani, including books, courses, coaching + consulting, and her one-of-a-kind, critically acclaimed POP PROPAGANDA DIGITAL MEDIA LITERACY COURSE:www.danikatz.comPlus, schwag:danikatz.threadless.com Find Kristen and sign up for her Rise and Shine course (with me!):www.kristengilbert.ca Show notes:· Why healthy routines collapse when life improves· The nervous system's “upper limit” on joy· Trauma, self-sabotage & subconscious contraction· How somatic work expands your capacity for happiness· Light hygiene & circadian rhythm as nervous system repair· Metabolic (exclusion zone) water & mitochondrial health· The role of grounding + sunrise exposure· Anger as a mobilizing force (not a spiritual flaw)· Belonging vs fitting in· Slowing down as a revolutionary act

In this episode, I talk with Dr. Tommy Wood about how to protect and strengthen brain health across the lifespan—how overstimulation, chronic stress, and not giving your brain time to rest and recover undermines focus and productivity, and why restructuring your workday, prioritizing sleep, and building in real cognitive breaks can help you think more clearly and perform better. We discuss how the balance of stimulus, supply, and support shifts as we age, why retirement and prolonged illness can accelerate cognitive decline without ongoing challenge, and how physical activity, deep work, and continued learning help maintain function and even build “crystallized intelligence”—wisdom—later in life. We also get into genetic risk and why it’s largely a probability game where lifestyle can stack the deck in your favor; the powerful role of social connection and helping others in reducing dementia risk; how to use digital tools for real connection instead of passive consumption; and the cognitive effects of substances like nicotine, alcohol, cannabis, and stimulants. Dr. Tommy shares practical strategies—from structuring your day around focused work and restorative breaks to picking hobbies that challenge your brain—as well as simple ways to maintain cognitive function, extend the time you stay sharp, and lower the likelihood of decline over your life. TIMESTAMPS: Tommy Wood's new book explains the environmental impact on your brain health. [01:07] In adults over 40, dementia is the number one health concern. [07:21] Why haven't we done a better job of understanding the brain's neurological disease? [13:28] Studies have shown that an older adult learning a new language or musical instrument, experiences significant changes in the structure of the brain. [20:45] Failure is the primary driver of neuroplasticity. [21:35] If you do one of two activities such as attending lectures, writing, classes, volunteering, sports and such, you are best protected from dementia. [ 26:00] What are the three S's that are the key to long-term brain health and disease prevention? [29:08] Metabolic disease like high blood pressure is a significant risk factor for dementia. [35:13] People who are stressed usually don't give their brain time to recover. [36:03] Some people do have genetic influence and possibly have a higher risk that they can learn to work with. [38:33] It's estimated that 45 to 70 ish percent of dementias are preventable. [39:53] We can eliminate this accelerated decline that we are seeing around us by hitting the checkpoints like move, nourish, stimulate, connect and adapt. [47:06] The social connection is terribly important. [47:43] The areas of the brain that are most susceptible to decreases in function as we age, are the areas of the brain that are negatively impacted by being socially isolated. [51:27] What is the impact of the digital world that surrounds us? What about smoking and alcohol? [52:26] Marijuana use definitely has an effect on brain. [01:02:46] If someone only has a small amount of time to learn these things, what would be the tips you would give them? [01:07:34] LINKS: Brad Kearns.com BradNutrition.com - 20% OFF Your First Order! B.rad Superdrink – Hydrates 28% Faster than Water—Creatine-Charged Hydration for Next-Level Power, Focus, and Recovery B.rad Whey Protein Superfuel - The Best Protein on The Planet! Brad’s Shopping Page BornToWalkBook.com B.rad Podcast – All Episodes Peluva Five-Toe Minimalist Shoes Dr. Tommy Wood Instagram @drtommywood The Stimulated Mind: Future-proof your Brain Podcast with Wood: Metabolic Efficiency Podcast with Wood: Sensible Healthy Living Podcast with Wood: Beauty of Not Always Optimizing Nourish Balance Thrive Dr.TommyWood.com We appreciate all feedback, and questions for Q&A shows, emailed to podcast@bradventures.com. If you have a moment, please share an episode you like with a quick text message, or leave a review on your podcast app. Thank you! Check out each of these companies because they are absolutely awesome or they wouldn’t occupy this revered space. Seriously, I won’t promote anything that I don't absolutely love and use in daily life: B.rad Nutrition: Premium quality, all-natural supplements for peak performance, recovery, and longevity; including the world's highest quality whey protein! Get 20% OFF your first order! Peluva: Comfortable, functional, stylish five-toe minimalist shoe to reawaken optimal foot function. Use code BRADPODCAST for 15% off! Get Stride: Advanced DNA, methylation profile, microbiome & blood at-home testing. Hit your stride the right way, with cutting-edge technology and customized programming. Save 10% with the code BRAD. Online educational courses: Numerous great offerings for an immersive home-study educational experience Primal Fitness Expert Certification: The most comprehensive online course on all aspects of traditional fitness programming and a total immersion fitness lifestyle. Save 25% on tuition with code BRAD! See omnystudio.com/listener for privacy information.

Dr. Mark Tarnopolsky's VO2 max was once 87.6 ml/kg/min — an elite-level mark few humans have reached. He's competed at three world championships in three different sports. He's also had three cardiac ablation surgeries, bled from his bowels after races, and watched his vision tunnel to a speck crossing a finish line. His story is a master class in where the line falls between peak performance and self-destruction.Now 63, Tarnopolsky is a neurologist, neuromuscular disease specialist, and supplement formulator who has channeled decades of elite athletic experience and hundreds of published studies into the idea that keeping metabolic throughput high is what protects us as we age.In this conversation with Dom D'Agostino, he shares practical strategies anyone can apply: why resistance training three times per week is non-negotiable after 50, why post-exercise nutrient timing improved performance in a simulated training camp with identical calories, why he says creatine belongs in nearly everyone's regimen, and why he personally takes his mitochondrial supplement stack situationally after hard efforts rather than daily.Questions Answered in This Episode:What is the only intervention proven to extend human lifespan — and by how much?At what point does endurance exercise become pro-aging — and what are the warning signs?What simple nutrient timing strategy improved performance with zero extra calories?How did a bodybuilder bar conversation lead to a published discovery about growth hormone and collagen?What muscle and bone costs of Ozempic aren't getting enough attention?Why did elite endurance athletes need nearly as much dietary protein as bodybuilders — and why were bodybuilders massively overconsuming?This conversation reframes the longevity debate around what's actually been proven in human clinical trials — not Petri dishes, not animal models, and not social media influencers.Special thanks to the sponsors of this episode:✅ Troscriptions – Get 10% off your first order with code METABOLICLINK here.✅ Toups and Co – Get 15% off your first order with code METABOLIC here.✅ iRestore – Get a huge discount on the Elite and the Illumina bundle here. ✅ MudWtr – Get up to 43% off + free shipping and a free rechargeable frother with code METABOLICLINK here.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

ReferencesGuerra, DJ 2026. Unpublished LecturesThe Journal of Biological Chemistry 2018 293, 19001-19011 Int J Mol Sci. 2025 Apr 27;26(9):4147Cell Death & Disease 2019. v 10, Article number: 315 Hunter/Garcia/Kreutzmann. 1975 Franklin's Tower. Grateful Dead.https://open.spotify.com/track/3PgIhd4XmwtmV2XGU5qhzZ?si=7714f01313ca477bTravis, M. 1946. !6 Tons. Tennessee Ernie Fordhttps://open.spotify.com/track/3P6OwCX7Ofiaaqtvujb6i5?si=4b8704749b6e4390

Dr. Frank Dumont is Executive Medical Director at Virta Health, where he leads medical strategy to advance safe, scalable metabolic care. A longtime internal medicine physician at Estes Park Medical Center, he previously directed its Wellness Service Line. A Fellow of the American College of Physicians, Dr. Dumont has also served in leadership roles with the Colorado Medical Society and the American Medical Association. In this episode, Drs. Brian and Frank talk about… (00:00) Intro (04:03) How Dr. Frank's personal health issues and professional experiences as a doctor led him to adopt a metabolic health approach to healing himself and his patients (10:41) Exercise, nutrition, and de-prescribing  (14:22) Fat adaptation and fasting (24:09) Virta's peer-reviewed publications and long-term data (30:09) The positive cascading effect on holistic health of metabolic lifestyle interventions (36:25) Social support and mental health (44:41) Dr. Frank's experience leaving a standard medical practice and becoming a metabolic health practitioner (52:22) Moral injury and physician burnout in the standard medical care system (54:05) Employe wellness and metabolic health care (01:01:01) Outro/plugs For more information, please see the links below. Thank you for listening! Links: Please consider supporting us on Patreon: https://www.lowcarbmd.com/   Dr. Frank Dumont: Virta Health: https://www.virtahealth.com/ X: https://x.com/FrankDumont Linkedin: https://www.linkedin.com/in/frank-d-dumont-46aa00b7/ Dr. Brian Lenzkes:  Website: https://arizonametabolichealth.com/ Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author Dr. Tro Kalayjian:  Website: https://toward.health Twitter: https://twitter.com/DoctorTro IG: https://www.instagram.com/doctortro/ Toward Health App Join a growing community of individuals who are improving their metabolic health; together.  Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.  Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888  Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US Learn more: https://toward.health/community/

Every single week in my clinic, I see smart, motivated people stuck in their weight loss journey not because they're doing something wrong, but because they believe something wrong. The myths surrounding weight loss are so deeply embedded in our culture that even some physicians still repeat them. And the cost? Shame, delayed treatment, and people giving up on themselves unnecessarily. I've spent over a decade watching these myths do real damage and I'm done staying quiet about it. In this episode, I'm breaking down the top 5 weight loss myths I wish my patients would stop believing and replacing them with what the science actually says. If you've ever said "I just need more willpower" this episode is for you. Listen now!   Episode Highlights: Why "calories in, calories out" is an oversimplification of a complex metabolic system How metabolic adaptation explains why what worked before stops working Why obesity is a chronic, relapsing disease  The truth about weight loss medications and why using them is NOT cheating Why the scale is just data, not a report card, and what metabolic progress really looks like Why stopping everything after weight loss leads to weight regain, and what to do instead   Connect with Dr. Alicia Shelly: Website | drshellymd.com Facebook | www.facebook.com/drshellymd Instagram | @drshellymd Linked In | www.linkedin.com/in/drshellymd Twitter | @drshellymd   About Dr. Alicia Shelly Dr. Alicia Shelly was raised in Atlanta, GA. She received her Doctorate of Medicine from Case Western Reserve University School of Medicine in Cleveland, OH.  Dr. Shelly has been practicing Primary Care and Obesity medicine since 2014.  In 2017, she became a Diplomat of the American Board of Obesity Medicine. She is the lead physician at the Wellstar Medical Center Douglasville. She started a weekly podcast & Youtube channel entitled Back on Track: Achieving Healthy Weight loss,  where she discusses how to get on track and stay on track with your weight loss journey. She has spoken for numerous local and national organizations, including the Obesity Medicine Association, and the Georgia Chapter of the American Society of Metabolic and Bariatric Surgeons. She has been featured on CNN, Fox 5 News, Bruce St. James Radio show, Upscale magazine, and Shape.com. She was named an honoree of the 2021 Atlanta Business Chronicle's 40 under 40 award. She also is a collaborating author for the, "Made for More: Physician Entrepreneurs who Live Life and Practice Medicine on their own terms''.   Resources: FREE! Discover the 5 Reasons Your Weight-Loss Journey Has Gotten Derailed (And How To Get Back On Track!)

In this episode Andrea Samadi interviews Thoryn Stevens, CEO and founder of Brain.One, about using AI, wearables, biomarkers and evidence-based micro-habits to create personalized brain-health protocols. Watch our full interview on YouTube here https://www.youtube.com/watch?v=r9UN9kev2CE or listen and follow the show notes here https://andreasamadi.podbean.com/e/can-ai-personalize-your-brain-health-inside-brainones-protocols/  What We Covered on EP 386 with Thoryn Stephens The Problem with Generic Wellness Advice Why most health advice fails to translate into sustained behavior change The gap between research findings and real-world application Why optimization must be systematic, not inspirational From Data to Daily Micro-Habits How Brain.One analyzes peer-reviewed research using AI Turning biometrics (HRV, sleep data, metabolic markers) into actionable protocols Why small, consistent micro-habits compound into long-term neuroplastic change Wearables & What Actually Matters The most misunderstood wearable metrics HRV, sleep architecture, and recovery as early indicators of cognitive health How to avoid becoming obsessive with numbers while still using data intelligently Dementia Prevention & Cognitive Longevity Evidence-based strategies inspired by the Lancet dementia prevention framework Why metabolic health and inflammation play a critical role in brain aging Prevention vs. reversal: when to start optimizing brain health Biological Bottlenecks to Human Potential Stress dysregulation as a performance limiter Sleep architecture and glymphatic clearance Metabolic flexibility and mitochondrial function Why emotional regulation remains foundational to cognitive performance AI in Health: Hype vs. Evidence What makes Brain.One's system evidence-constrained How AI can scale personalized health protocols The future of data-driven behavioral optimization

Nearly 90% of Americans suffer from metabolic disease, Manu Diwakar tells us, citing a recent McKinsey & Company study. For Diwakar, CFO of Virta Health, that statistic defines both the scale of the challenge and the clarity of the mission.Metabolic disease, he explains, includes type 2 diabetes, obesity, liver disease, kidney disease, heart disease, and high blood pressure—“branches of a tree,” he tells us, all sharing the same root cause: poor nutrition. Virta's model blends medical professionals and technology to reverse those conditions, partnering with insurers, employers, and government entities in a B2B2C framework.From a finance perspective, the impact is measurable. Diwakar tells us Virta uses pharmacy and medical claims data to compare enrolled members with non-enrolled employees who share the same conditions—creating what he describes as a “really clean A/B test.” For type 2 diabetes, the company delivers a “two-to-one ROI,” he tells us, making the value proposition tangible.In a market captivated by GLP-1 drugs, the numbers sharpen further. Virta charges about $150 per month, Diwakar tells us, compared with roughly $1,000 per month list price for GLP-1s—about $500 after rebates. More important, he notes that when patients stop GLP-1s, weight often returns. By targeting the root cause—nutrition habits—Virta aims to make results sustainable and long-lasting, he tells us.For Diwakar, disciplined measurement and root-cause thinking align strategy with impact—improving health while lowering cost.

ReferencesStem Cell Res Ther. 2018 Dec 7;9:342Developmental Cell. 2024. V.59, Issue 2:211-227.e5January 22, Cell Commun Signal. 2023 Sep 19;21:244.Cell Discov 2024. 10, 71.Baker/Taylor. 1968 Passing the Time Cream WoFhttps://open.spotify.com/track/7wxd5oR50LKSTtqqJQxYSX?si=4e7a91cc8f6e463cPisendel, JG. 1717. Sonata in G Minorhttps://music.youtube.com/watch?v=beAdy0DoWEk&si=CCs2BQwfundJ65-u

Dr. Saadia Mian covers the medical dos and don'ts of fasting, tips on staying healthy while fasting, and how fasting impacts insulin resistance, fertility, testosterone, weight gain, and more!

ReferencesJ Biol Chem 2017 292: 20481.Cell Metabolism. 2018. 27.,3 p602-615.e4March 06Proc Natl Acad Sci U S A. 2010 May 8;107(21):9626–9631Proc Natl Acad Sci U S A. 2011 May 18;108(23):9466–9471Guerra,DJ. 2026. Unpublished LecturesHoward, B. 1954.Fly Me to the Moon. Sinatrahttps://open.spotify.com/track/7FXj7Qg3YorUxdrzvrcY25?si=3104a016654d4bb9Sparks, A. "Pinetop" 1935. Every Day I Have the Blues. Count Basis and Joe Williamshttps://open.spotify.com/track/1ZVV4uUYilEdZRySfKjvpx?si=62de0af91e7648f0Kaukonen, J. 1971. Third Week in Chelsea. JAhttps://open.spotify.com/track/5t5bV1HLuULF0bX1F6MfCv?si=d65795563a324df7

Fat loss stalled? Low energy? It might not be calories — it could be fatty liver. In this episode, Ben explains how fatty liver silently slows metabolism long before symptoms appear, and why it is one of the most overlooked reasons for stubborn weight gain. You'll learn: • How liquid sugar and constant snacking overload the liver• Why insulin is the real fat-storage hormone• The power of a simple 12–16 hour fasting window• How walking after meals can blunt insulin spikes by over 30 percent• Why sleep is essential for restoring liver insulin sensitivity• The truth about fruit, alcohol, and dietary fat• Why coffee can either heal or harm your liver depending on quality Ben also breaks down how to reverse fatty liver naturally with a simple 3-step protocol: remove the overload, restore insulin signaling, and support detox. Plus, he shares a free egg-based protocol designed to help you lose the last 10 pounds while improving liver health. If your metabolism feels stuck, this episode will help you understand why — and what to do about it. Share this with someone who needs it and remember to practice Vitamin G: gratitude. New customers get 20% off with code BENAZADI at https://bit.ly/4rV6vEE  FREE GUIDE: How To Lose 1 Pound Of Fat Per Day HERE - https://bit.ly/4j45Yxa

ReferencesBMC Biology2011 9:85Biomedicines 2023, 11(7), 1804Cancer Res (2011) 71 (2): 293–297Biophysics J. 2018. Volume 114, Issue 1, 9 January: 126-136Proc Natl Acad Sci U S A. 2024 Jan 4;121(2):e2311700120. Guerra, DJ. 2026. Unpublished Lectures.Aurelius Augustinus Hipponensis. St. 387 De libero arbitrio voluntatis.Hunter/Garcia. 1974. Scarlet Begoniashttps://open.spotify.com/track/3euDGpS2R0NC2Xssqxohva?si=1985f2fff9f146d6Simon, P. 1969. The Boxer, S&G.BoTWhttps://open.spotify.com/track/76TZCvJ8GitQ2FA1q5dKu0?si=5e15f1cdf43a4083

This episode explores tadalafil (Cialis) as a potential longevity drug, though no randomized human trials prove it extends lifespan. Cialis works by blocking PDE5, enhancing nitric oxide signaling, and improving blood flow through vasodilation. Originally approved for pulmonary hypertension, it's also used for erectile dysfunction and BPH. Its 36-hour half-life makes it superior to Viagra for continuous longevity effects.   The host frames vascular aging and endothelial dysfunction as key drivers of age-related diseases (heart disease, stroke, dementia, kidney disease). Observational data shows Cialis users have 44% lower mortality, fewer cardiovascular events, reduced dementia risk, and lower mortality in diabetics. Additional benefits include improved cardiac function, reduced infarct size, arrhythmia suppression, and regression of left ventricular hypertrophy. A 2024 meta-analysis found it lowers hemoglobin A1C, possibly via improved microvascular perfusion, insulin sensitivity, and mitochondrial function.   Cialis crosses the blood-brain barrier and may improve neurovascular coupling and hippocampal plasticity, potentially benefiting those with or at risk of dementia. Safety is generally good with long-term daily use (2.5–5 mg), though cautions include avoiding use with nitrates, low blood pressure, or certain retinal disorders. Common side effects are headache, nasal congestion, and acid reflux. The host recommends consulting a doctor and references potential synergy with telmisartan.   Tadalafil (Cialis) — MedlinePlus drug info: [https://medlineplus.gov/druginfo/meds/a604008.html](https://medlineplus.gov/druginfo/meds/a604008.html) Sildenafil (Viagra) — MedlinePlus drug info: [https://medlineplus.gov/druginfo/meds/a699015.html](https://medlineplus.gov/druginfo/meds/a699015.html)   Key mechanisms mentioned Nitric Oxide (NO) — NCBI Bookshelf: [https://www.ncbi.nlm.nih.gov/books/NBK554485/](https://www.ncbi.nlm.nih.gov/books/NBK554485/) Cyclic GMP (cGMP) — NCBI Bookshelf: [https://www.ncbi.nlm.nih.gov/books/NBK542234/](https://www.ncbi.nlm.nih.gov/books/NBK542234/)   Conditions mentioned in the episode Benign Prostatic Hyperplasia (BPH) — MedlinePlus: [https://medlineplus.gov/benignprostatichyperplasia.html](https://medlineplus.gov/benignprostatichyperplasia.html) Pulmonary Arterial Hypertension (PAH) — MedlinePlus: [https://medlineplus.gov/pulmonaryhypertension.html](https://medlineplus.gov/pulmonaryhypertension.html)   Blood pressure drug mentioned Telmisartan — MedlinePlus drug info: [https://medlineplus.gov/druginfo/meds/a601249.html](https://medlineplus.gov/druginfo/meds/a601249.html)   Other longevity / comparison drugs mentioned Metformin — MedlinePlus drug info: [https://medlineplus.gov/druginfo/meds/a696005.html](https://medlineplus.gov/druginfo/meds/a696005.html) Sirolimus (Rapamycin) — MedlinePlus drug info: [https://medlineplus.gov/druginfo/meds/a602026.html](https://medlineplus.gov/druginfo/meds/a602026.html)   Side-effect helper mentioned Ibuprofen (Advil) — MedlinePlus drug info: [https://medlineplus.gov/druginfo/meds/a682159.html](https://medlineplus.gov/druginfo/meds/a682159.html)   Dementia meds mentioned Donepezil (Aricept) — MedlinePlus drug info: [https://medlineplus.gov/druginfo/meds/a697032.html](https://medlineplus.gov/druginfo/meds/a697032.html) Amantadine — MedlinePlus drug info: [https://medlineplus.gov/druginfo/meds/a682064.html](https://medlineplus.gov/druginfo/meds/a682064.html)   Lab markers mentioned Hemoglobin A1C (HbA1c) test — MedlinePlus lab test: [https://medlineplus.gov/lab-tests/hemoglobin-a1c-hba1c-test/](https://medlineplus.gov/lab-tests/hemoglobin-a1c-hba1c-test/) Insulin in blood test — MedlinePlus lab test: [https://medlineplus.gov/lab-tests/insulin-in-blood/](https://medlineplus.gov/lab-tests/insulin-in-blood/)   People referenced (where the claims were mentioned) Huberman Lab (Dr. Andrew Huberman) — site: [https://www.hubermanlab.com/](https://www.hubermanlab.com/) Clip about low-dose tadalafil (2.5–5mg) — X post: [https://x.com/tbpn/status/2022350426394534334](https://x.com/tbpn/status/2022350426394534334) Bryan Johnson (Blueprint) — site: [https://blueprint.bryanjohnson.com/](https://blueprint.bryanjohnson.com/) Dr. David Sinclair (Harvard profile) — site: [https://sinclair.hms.harvard.edu/people/david-sinclair](https://sinclair.hms.harvard.edu/people/david-sinclair)   Show Notes   00:00 Welcome to the Hart2Heart Podcast. 01:56 What Cialis Is: PDE5 Inhibition, cGMP & Nitric Oxide Explained 03:43 Approved Uses & Origin Story: Pulmonary Hypertension, ED, and BPH 05:33 Why Cialis Over Viagra: 36-Hour Half-Life & 24/7 Vascular Benefits 06:52 Vascular Aging 101: Endothelium, Perfusion, and Why It Drives Disease 11:14 What the Human Data Shows: Observational Evidence for Mortality, CVD & Dementia 13:04 Mechanisms Deep Dive: Heart Protection, Heart Failure, and Anti-Atherosclerosis 15:02 Cialis for Diabetics: Lowering A1C and Improving Insulin Sensitivity 16:21 Brain Effects: Blood–Brain Barrier, Neurovascular Coupling & Dementia Potential 18:21 Safety, Who Should Avoid It, and Daily Longevity Dosing (2.5–5 mg) + Wrap-Up   The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to cutting through the noise and uncovering the most effective strategies for optimizing health, longevity, and peak performance. This podcast dives deep into evidence-based approaches to hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise protocols, leveraging sunlight, and de-prescribing pharmaceuticals — using medications only when absolutely necessary. Beyond health science, we explore the intersection of public health and politics, exposing how policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being. Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen). If you're ready to take control of your health and performance, this podcast is for you.We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect with Dr. Mike Hart Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart

In Part 2 of this conversation, we're clarifying an important distinction: chronic undereating that leads to biological binge responses is not the same as biblical gluttony.Gluttony is a heart issue — replacing our need for God with food.But many women are not struggling because they love food too much.They're struggling because they've been under-fueling their bodies for years.In this episode, Rachel unpacks:The difference between gluttony and biological survival responsesWhat chronic calorie restriction does to hormones and metabolismWhy restriction often backfires for fat lossWhat reverse dieting is and how it worksWhy slowly increasing calories can restore metabolic trustHow maintenance phases actually support long-term fat lossWhy reverse dieting can be a worshipful act of stewardshipIf you've believed the lie that you must restrict forever to see results, this episode will reframe everything.What You'll LearnWhy gluttony and biological binge cycles are not the same thingHow leptin, ghrelin, cortisol, and thyroid hormones respond to chronic dietingSigns your metabolism may be suppressedWhy eating more strategically can reduce binge urgesHow reverse dieting increases metabolic capacityWhy maintenance is not failure — it's foundationalHow to cycle between maintenance and deficit wiselyScripture Referenced1 Corinthians 6:19–20“Do you not know that your body is a temple of the Holy Spirit within you… You are not your own, for you were bought with a price. So glorify God in your body.”Ready for Structure?If this episode resonated with you, Rachel's next FASTer Way round is open. Inside, women learn how to:Reverse diet safely (when appropriate)Support metabolism and hormonesUse carb cycling strategicallyStrength train effectivelyCycle between maintenance and fat loss phasesSteward their bodies with wisdom and faithDoors are open now.I am always love to connect with you!Don't hesitate to reach out!Personal Instagram: @racheljmitchellPodcast Instagram: @livingonmissionpodEmail: rachel@racheljmitchell.comJoin my 21 Day Metabolic Reset

Welcome to Resiliency Radio with Dr. Jill Carnahan, where today's episode uncovers a critical and often overlooked driver of chronic symptoms in women: meta-inflammation. Dr. Jill is joined by Dr. Lara Zakaria, widely known as The Foodie Farmacist, for a practical, empowering conversation on how inflammation, metabolism, stress, and lifestyle intersect in women's health. In this episode, Dr. Jill Carnahan and Dr. Lara Zakaria explore why so many women feel exhausted, inflamed, and burned out—despite doing "all the right things." Drawing from Dr. Zakaria's journey from retail pharmacy to functional and personalized nutrition, this conversation reveals why addressing root causes—not just symptoms—is essential for long-term resilience. This episode is for women who want clarity, sustainable strategies, and permission to stop striving for perfection while still supporting deep healing. ✨ Like, subscribe, and share to help more women reclaim energy, balance, and metabolic health.

➡️ Get the full episode breakdown at Biology of Trauma® Podcast -  Episode 161: Dopamine and Depression: The Metabolic Link You Need to KnowDopamine doesn't just create pleasure. It signals unexpected experiences and primes the brain to learn. New research reveals that depression, anxiety, and ADHD have different metabolic phenotypes. Understanding your unique metabolic footprint explains why standard treatments work for some and not others. Mental health and metabolic health are inseparable.In This Episode You'll Learn:[01:00] How does peripheral nerve stimulation affect dopamine in the brain?[06:30] Does dopamine actually make you feel good?[13:00] What is the real function of dopamine in learning and memory?[15:30] How does trauma change the way we perceive reality?[22:00] What are metabolic phenotypes in mental health conditions?[27:00] Why does the same diagnosis look different in different people?[33:00] How are metabolism, hormones, and mental health connected?[37:00] What role does the hypothalamus play in emotional and metabolic regulation?[44:00] Why do negative experiences affect us more than positive ones?[47:00] What does anchoring to something unchangeable mean for recovery?Resources/Guides:Learn more about Dr. Kyle Bills' ResearchThe NeuroNova Seat: Dopamine-releasing neuromodulation device.Year-long Biology of Trauma® immersion program with coursework on stress, grief, attachment, letting go, freeze, and neuroplasticity. Available for self-help individuals and practitioners seeking certification.Foundational Journey — Six weeks to clean up your internal environment so repair becomes possible. This is where we create the conditions for cellular healing. Prerequisite for the Year of Transformation program.The Biology of Trauma book — Get your copy hereRelated Podcast Episodes:Episode 5: How Genetics & Epigenetics Affect In-Utero Development (Part 1) with Dr. William Walsh Episode 6: The Role of Methylation & Epigenetics in Mental Health Outcomes (Part 2) with William Walsh

Send a textIn episode #174 we discussed Dr. Jose Areta's latest research, including:How energy deficits influence muscle protein synthesis and qualityThe role of mitochondrial proteins and their upregulation during energy restrictionPractical implications for timing and periodization of caloric deficits in training cyclesHormonal signals and their interaction with muscle adaptation during energy deficitsAssociate Professor Dr. José L. Areta is a leading scholar in Exercise Metabolism and Nutrition in the School of Sport and Exercise Sciences at Liverpool John Moores University (LJMU). His research investigates how nutrition and exercise interact to influence both performance and health. He focuses on the timing and composition of macronutrients — carbohydrates, proteins, and fats — and how they affect training adaptation. José also examines the role of dietary supplements in optimizing athletic performance, as well as the endocrine and metabolic consequences of energy restriction, particularly low energy availability. He has contributed influential studies on how severe calorie deficits combined with exercise can alter muscle quality and metabolism. José's work links cellular-level changes in muscle to practical nutrition strategies for athletes facing weight-sensitive sports or energy restriction.Please note that this podcast is created strictly for educational purposes and should never be used for medical diagnosis or treatment.Follow Jose Areta's research: Study discussed, Endocrine, Metabolic, and Skeletal Muscle Proteomic Responses During Energy Deficit With Concomitant Aerobic Exercise in Humans: https://faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202502384RRIG: https://www.instagram.com/jose_l_aretaWeb: https://profiles.ljmu.ac.uk/13460-jose-aretaResearch: https://scholar.google.com/citations?user=8tP0vzUAAAAJ&hl=enMentioned:A Systematic Review and Meta-Analysis on the Association and Differences between Aerobic Threshold and Pint of Optimal Fat OxidationCreatineBeta-alanineMORE NR Save 10% on our website with code NEWPOD10 Apply to work with us, click here: https://nutritional-revolution.com/ Interested in having your biomarkers or nutrigenomics checked? Email us at nutritionalrev@gmail.com Follow us @nutritionalrevolution Save 20% on supplements at our trusted online source: https://us.fullscript.com/welcome/kchannell Join Nutritional Revolution's The Feed Club to get $20 off with an additional $20 Feed credit drop every 90 days.: https://thefeed.com/teams/nutritional-revolution If you're interested in sponsoring Nutritional Revolution Podcast, shoot us an email at nutritionalrev@gmail.com.

In this episode, Ben Azadi explains the five metabolic levels of fat loss and why most people feel stuck despite dieting, exercising, and eating “clean.” Fat loss is not about willpower or calories. It is about hormones, inflammation, and metabolic signaling. Many people fail because they are using the wrong strategy for the metabolic level their body is currently in. Ben breaks down each level, from the Frozen Phase, where the body is in survival mode and unable to burn fat, to Fat-Burning Freedom, where fat loss becomes effortless and sustainable. You will learn: Why caloric restriction and excessive cardio backfire How insulin resistance and inflammation block fat loss Why eating clean is not enough without proper timing and protein How intermittent fasting, strength training, and recovery reset metabolism What it truly takes to lose 25–50+ pounds and keep it off This episode reframes fat loss as a metabolic progression and provides clarity for anyone who has struggled with plateaus, rebounds, or frustration on their health journey.

Stay Connected Beyond the Podcast Subscribe to our Substack to get episode updates, event announcements, wellness tips, and personal thoughts from Marnie and Stephanie delivered straight to your inbox. If you love the show and want to support what we're building, consider a paid subscription for $30 annually. Your support helps fund podcast production and allows us to continue bringing you meaningful, high-quality conversations. https://theartoflivingwell.substack.com/ What if your symptoms weren't random — and aging didn't have to mean decline? In this in-depth and highly practical episode, we explore how understanding your unique biology, labs, and lifestyle can completely change your health trajectory. In this powerful conversation on The Art of Living Well Podcast®, hosts Marnie Dachis Marmet and Stephanie May Potter welcome back Dr. Stephen Cabral for a third time. Dr. Cabral dives deep into the principles of Personomics, root-cause healing, and why testing — not guessing — is essential for long-term health and longevity. Together, they walk through real lab results on air, explain what common imbalances actually mean, and break down why most people normalize symptoms that are early warning signs from the body. From gut health and mold exposure to neurotransmitters, stress, genetics, and aging, this episode offers clarity, reassurance, and a clear roadmap for healing. _______________________________________ What You'll Learn in This Episode: ● What Personomics is and how it differs from traditional medicine ● The difference between chronological age and biological age ● How to identify the early signs your body is out of balance ● Why most people feel "fine" but are actually compensating ● The power of functional medicine lab testing vs. guessing ● What gut, vitamin, and neurotransmitter labs can reveal ● How stress, mold, and lifestyle impact energy and resilience ● Why supplements alone don't heal — and when they do matter ● How to personalize protocols without overdoing it ● How to build a sustainable, boring routine that supports longevity _______________________________________ Noteworthy Quotes from the Episode: ● "All symptoms trace back to deficiencies or toxicities." – Dr. Stephen Cabral ● "You don't heal by adding more — you heal by removing what doesn't belong." – Dr. Stephen Cabral ● "Your genetics are real, but they are not your destiny." – Dr. Stephen Cabral ● "You never truly know what's going on until you test." – Dr. Stephen Cabral ● "Most people think they're fine because they've normalized their symptoms." – Dr. Stephen Cabral ● "There's a system to healing — it's not guesswork." – Dr. Stephen Cabral _______________________________________ Episode Breakdown with Timestamps: 00:00 - Trailer & Intro 02:15 - Why feeling "okay" is not the same as being healthy 06:00 - Deficiencies vs toxicities and why supplements fail 10:55 - The Rain Barrel Effect and stress accumulation 16:00 - Why genetics does not control your health 21:30 - The flaw in one-size-fits-all medicine 26:40 - Early body signals before chronic disease 31:00 - Why lab testing beats guessing 41:30 - Stress, dopamine, and burnout in high performers 52:30 - Longevity, anti-aging, and health after 40 _______________________________________ Wellness Resources for Everyday Health: This is the exact functional lab test discussed on the show. The Stephen Cabral Candida, Metabolic, and Vitamins Test provides insight into gut health, metabolism, and key nutrient levels. Get $150 off at stephencabral.com/livingwell  _______________________________________ Looking for a clean, plant-based boost for energy, focus, and immunity? We love ENERGYbits algae tablets—a simple, nutrient-dense superfood made from pure algae.

Weak grip strength is not a normal part of aging. It is often an early warning sign of metabolic dysfunction. In this episode, Ben explains how issues like insulin resistance, chronic inflammation, mitochondrial decline, and mineral depletion can weaken nerve signaling and muscle function, especially in the hands. Grip strength is one of the strongest predictors of longevity, independence, and overall metabolic health. You'll learn why people can look fit yet still struggle with weak hands, cramping, or fatigue, and how these symptoms often appear years before serious disease. Ben breaks down the four main root causes behind grip weakness and shares a simple daily protocol to restore strength. The episode covers insulin resets, nutrition strategies, mineral support, protein intake, grip training, and the role of creatine in improving strength and muscle signaling. Ben also explains why chronic stress and inflammation accelerate metabolic decline and how gratitude can positively impact metabolism. This episode offers practical, actionable steps you can start today to rebuild grip strength, improve energy, and protect long-term metabolic health. CLICK To Get Your Creatine - MYOXCIENCE Use Coupon Code "FREEDOM" for 25% off - https://bit.ly/4qTgABP