The set of life-sustaining chemical transformations within the cells of organisms
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Alzheimer's doesn't begin with memory loss. It begins years earlier with metabolic dysfunction. In this episode, Ben Azadi reveals why Alzheimer's is now being referred to as “Type 3 Diabetes” and how insulin resistance, inflammation, and chronic stress silently damage the brain long before symptoms appear. You'll learn why genetics are not your destiny, how the brain becomes starved for fuel despite high blood sugar, and why waiting for symptoms is already too late. Ben breaks down the science behind hippocampal shrinkage, reduced glucose uptake in the brain, and the role of cortisol in cognitive decline. This episode introduces the 15-Minute Brain Reboot, a simple daily protocol designed to protect and rebuild brain health: Daily fasting to switch the brain's fuel from sugar to ketones Zone 2 movement to increase blood flow and grow new brain cells Gratitude (“Vitamin G”) to lower stress hormones and protect neurons Ben also answers common questions about genetics, brain games, fasting safety, supplements, and why prevention isn't emphasized in conventional medicine. The takeaway is clear: you're not broken, you're early. With consistent daily habits, your brain can heal, adapt, and stay sharp for decades to come.
A new Nutrients study shows that drinking 12 ounces of 100% elderberry juice daily for a week helped overweight adults activate more genes that regulate how the body uses energy after meals than a placebo Elderberry juice turned on processes that help the body manage energy better — making it easier to switch between burning carbohydrates and fat for fuel Earlier research from Washington State University showed elderberry juice improved blood sugar control, increased fat burning, and shifted energy use during meal challenges Practical tip: Aim for about 12 ounces of unsweetened, 100% elderberry juice daily for seven days. Check labels to avoid added sugars, as unsweetened juice still contains about 30 to 36 grams of natural sugar per eight-ounce serving Safety first: Never eat raw elderberries, check for medication interactions (such as immunosuppressants or diabetes drugs), and consult a healthcare provider before using if you are breastfeeding or have an autoimmune condition
Today, I'm joined by the incredible Anthony Castore, a trailblazer who fuses elite strength coaching with deep cellular medicine. In our conversation, Anthony shares his journey from a young athlete determined to defy genetic odds to becoming an expert in both physical training and the nuanced science of peptides, mitochondria, and bioregulators. Use code NAT10 for 10% off products at https://alchemiqlabs.com/ Episode Timestamps: Welcome and episode introduction ... 00:00:00 Anthony Castore's path from strength coaching to cellular medicine ... 00:05:55 Connecting strength training with cellular pathways (AMPK, mTOR) ... 00:12:27 Explaining and balancing AMPK and mTOR for performance ... 00:13:03 Training strategies: Metabolic, hypertrophy, and neural approaches ... 00:18:18 Building a solid foundation: Lifestyle, training, nutrition, peptides ... 00:23:04 Assessing recovery capacity and individualizing protocols ... 00:26:02 Mitochondrial fission, fusion, and targeted adaptation ... 00:29:57 Optimizing muscle gain and fat loss through calories and recovery ... 00:31:00 Differentiating bodybuilder vs. longevity approaches ... 00:34:44 Integrating peptides and support molecules into routines ... 00:40:44 Ketone esters and mitochondrial peptide interventions ... 00:41:20 Cautions on stacking and combining interventions ... 00:54:04 Lessons learned from overdoing interventions ... 01:05:02 Our Amazing Sponsors: Vitali - combines pharmaceutical-grade copper peptides with zero-age exosomes to support clearer cellular signaling and long-term skin resilience, working with your biology instead of forcing change. Visit VitaliSkincare.com and use code NAT20 for 20% off. BEAM Minerals - Low energy often starts in the mitochondria. Support cellular energy with a bioavailable liquid mineral supplement — and get 20% off at beamminerals.com with code NAT20. Complete Liver Complex by LVLUP Health - supports your liver's natural detox pathways so your body can reset after the holidays without suffering. Go to lvluphealth.com and use code NAT for 20% off. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group
Get Fitness Lab (20% off for listeners), the #1 coaching app that adapts to YOUR recovery, YOUR schedule, and YOUR body. Build muscle, lose fat, and get stronger with daily personalized guidance. Now with Apple Health integration.--Are biohacks keeping you stuck instead of helping you lose fat and build muscle? Why does body recomp feel so hard even when you are doing all the “right” things?Body recomp, build muscle, and lose fat come up constantly on fitness podcasts, but I keep seeing the same mistake. People chase cold plunges, red light therapy, peptides, and supplements while ignoring the basics of nutrition and fitness. I sat down with Jenn Trepeck, author of Uncomplicating Wellness and host of Salad with a Side of Fries, to flip that script.We break down her concept of biostacking and why most people are operating at 50 to 60 percent capacity. We talk protein, fiber, hydration, sleep, stress, connection, and why metabolism only improves when the basics are in place. This conversation ties directly into Wits and Weights, evidence-based fitness, and evidence-based nutrition for sustainable weight loss, strength training, and long-term health.Today, you'll learn all about:0:00 – Why biohacks fail most people3:00 – Biohacking vs biostacking explained6:00 – Metabolic health reality check9:30 – Building a real foundation13:30 – Nutrition basics that matter18:00 – Movement and muscle building24:00 – Stress, sleep, and recovery31:00 – Connection and longevity38:00 – Where to start practicallyEpisode resources:Jenn's Book: Uncomplicating Wellness: Ditch the Rules. Quiet the Noise. Reclaim Your Life.Website: asaladwithasideoffries.comPodcast: Salad With a Side of FriesFacebook: @Saladwithasideoffriespodcast Instagram: @saladwithasideoffriespodYouTube: @jenntrepeck Support the show
In this episode of the NeuroVeda podcast, we sit down with Sujatha Reddy, LPC, BC-TAM, BAMS, a deeply experienced mental health clinician and Ayurvedic practitioner whose work bridges ancient wisdom and modern therapeutic practice. Sujatha is a Licensed Professional Counselor in Colorado and Ohio, a Licensed Natural Medicine Facilitator in Colorado, a Board-Certified Traditional Ayurvedic Medicine practitioner, certified psychedelic-assisted psychotherapist, holosomatic breathwork therapist, and yoga therapist. With over 35 years of Ayurvedic practice in the U.S. and 25 years in the mental health field, she brings a rare depth of perspective to the conversation. She is the founder and executive director of Ayumind LLC and Heartland Wellness PLLC, and also owns a Humanly mental health franchise in Lakewood, Colorado.Together, we explore the Ayurvedic understanding of mental health as a metabolic and systemic process rather than a standalone diagnosis. Sujatha explains the concept of the koshas, the layers of self, and how disconnection across these layers contributes to anxiety, depression, and emotional dysregulation. She shares how the gunas shape our mental and emotional states, and how practices like breathwork, meditation, mantra, yoga therapy, and personalized Ayurvedic protocols can release stored trauma and restore balance. This episode offers a powerful look at truly integrative mental health care, blending Ayurveda, Western psychology, and psychedelic-assisted psychotherapy to address root causes rather than symptoms, while emphasizing the importance of resilience, community, and reconnection to self in healing.TakeawaysAyurveda views mental health as a metabolic disorder.The mind is interconnected with the body and spirit.Understanding the koshas helps in addressing mental health.Disconnection from self leads to anxiety and depression.Breathwork can release trauma stored in the body.The gunas influence our mental and emotional states.Personalized programs are essential for mental health.Holistic approaches integrate body, mind, and spirit.Ayurvedic practices can enhance resilience and well-being.Community and social engagement are vital for mental health.
Derrick Van Every is a PhD candidate at Stu Phillips' Protein Metabolism Lab as well as a powerlifting and nutrition coach.In this episode, we discuss the topics he addressed in one of his recent published papers, namely:What are the main drivers of hypertrophy?Does the pump cause hypertrophy?What about training-related hormonal increases?… And more!Links and resources:Derrick's paper – “Load-induced human skeletal muscle hypertrophy: Mechanisms, myths, and misconceptions”: https://www.sciencedirect.com/science/article/pii/S2095254625000869Connect with Derrick on Instagram @derrick_cbb: https://www.instagram.com/derrick_cbb/ Sign up for one on one coaching with me: https://www.fittotransformtraining.com/coaching.htmlFollow me on Instagram @nikias_fittotransform: http://instagram.com/nikias_fittotransform/Visit my website: https://www.fittotransformtraining.comSign up for my free newsletter: https://mailchi.mp/157389602fb0/mailinglistSubscribe to my YouTube channel: https://www.youtube.com/@nikias_fittotransform Sign up for the No Quit Kit email series on retraining your mindset for long-term fat loss success: https://mailchi.mp/4b368c26baa8/noquitkitsignupTake my free “Should You Cut or Bulk First?” quiz: https://nikias-dddr9p81.scoreapp.com/
ReferencesAging Cell. 2023 Jul 9;23(1):e13920 bioRxiv [Preprint]. 2025 Mar 25:2025.03.22.644753Austin, G. 1926. Five foot Two Eyes of Bluehttps://open.spotify.com/track/2dloA2Xw41XN4kRrOgnx81?si=f6bd077287c54742Morton, GS 1965. Sophisticated Boom Boom . The Shangri-lashttps://open.spotify.com/track/29bV7N2KQ06j7sJQPrmrBv?si=62be726ab11545c6Garber, J. 1926 Baby Facehttps://open.spotify.com/track/2evkH9IeWX1VDZ9WPHoUvE?si=0267887ab15e4ce9Weatherly, F. 1910. Danny Boy. https://open.spotify.com/track/1VLTwDHRsJ9jYXGMktz3zk?si=83c148acbdcd4fb2
Dr. Andrew Best is a professor at the Massachusetts College of Liberal Arts where he focuses on evolutionary questions about human physiology. You can email him at andrew.best@mcla.edu. His latest study was titled "Ultra Endurance Athletes and the Metabolic Ceiling." They looked at the maximum, sustainable amount of energy expenditure that can be done over a long time period. It answers the question, "what is the limit of human energy expenditure?" It's a metric that literally dictates how hard you can train. If you want sustainable performance, you'll love this episode. Fan of the podcast? Support our partners! Thank you MOBO Board! Invented by renowned physical therapist Jay Dicharry, MOBO helps you stabilize your stance with an innovative rocker board that's set up on two fins. The design effectively forces you to drive your big toe into the board to improve your stability. I was pretty arrogant going into my first session on the MOBO Board. How hard can it be to balance, right? Well, I was humbled pretty quickly! Even if you're a good runner, better balance, stability, and proprioception is going to help you have a more powerful stride and prevent more running injuries. You'll learn how to improve the efficiency of the kinetic chain from your hip to your big toe. Because as Jay likes to say, it's not just how strong you are, but how well you use that strength. I was recently at a weekend physical therapy workshop (lol I was the only running coach) and learned how important (and rare) this simple movement is. Save 10% with code STRENGTHRUN10 at checkout at moboboard.com. The Ultimate Training Bundle Dial in your running, weight training, nutrition, and mindset - with certainty. Strength Running's Ultimate Training Bundle is a collection of our six most popular training programs at a huge, 35% discount. Since 2010, we've helped runners in dozens of countries race faster, get stronger, and prevent more injuries with our evidence-based training programs. You'll get High Performance Lifting, Injury Prevention for Runners, Bodyweight Power, Mindset Mastery, Nutrition for Runners, and Team Strength Running (our group coaching membership community). These multimedia courses offer coaching lessons, video demonstrations, interviews, injury treatment protocols, and even coaching with Jason. And the best part? Once you're a member, you get any and all updates and additions at no cost. Once you're in, you're family. Give yourself the gift of certainty: of knowing that you're doing the right thing with your training, strength work, nutrition, and mindset. And if you're not sure, you'll have access to Jason as your coach. Sign up here.
references FEBS J. 2008 Mar;275(5):1025-38Mol Med Rep. 2018 Sep 27;18(6):4793–4801Eur J Immunol. 2020 Oct 25;50(11):1643–1652Dawson, J. 1971 Last Lonely Eagle NRPShttps://music.youtube.com/watch?v=KU8kalZM4KE&si=kti7elgiZflGW3tjDylan, B. 1963 Don't Think Twicehttps://music.youtube.com/watch?v=Kv7K9ghgcgA&si=Qp33XJQDNvxK0k-BSchmelzer, JM 1664 Violin Sonatas Romanescahttps://music.youtube.com/playlist?list=OLAK5uy_k8TeNzQczMKnGy8h8DZ5Wgl_JEHxlc-m4&si=wplciKfIq96hReu2
On today's episode of The Wholesome Fertility Podcast, I'm joined by Gabriella Rosa @dr.gabrielarosa, a globally recognised fertility specialist and researcher, to unpack the truth about fertility after 40. We explore why age alone is not the real issue, what actually impacts egg and sperm quality, and how metabolic health, lifestyle factors, and emotional wellbeing play a much bigger role in conception than most people are told. Gabriella also shares insights from her clinical research and discusses the importance of addressing fertility-related trauma and stress. This episode offers clarity, hope, and evidence-based guidance for anyone navigating fertility in their late 30s and 40s. Key Takeaways: Fertility myths around age 35 and 40 Egg quality, sperm quality, and mitochondrial health Why fertility is a team effort Metabolic health and lifestyle factors that influence conception The emotional impact of infertility and why support matters Gabriella's clinical trial supporting emotional wellbeing in fertility Guest Bio: Gabriela Rosa @dr.gabrielarosa is a world-renowned fertility specialist, author, and Harvard-awarded scholar. She is the founder of The Rosa Institute and creator of the Fertility Breakthrough Program™, which has transformed the lives of over 140,000 couples in 110+ countries. Gabriela's work focuses on addressing the root causes of infertility using an evidence-based approach that combines modern science with natural medicine. With extensive training in reproductive health, naturopathy, and public health, Gabriela is passionate about empowering couples to achieve their dream of parenthood while improving their long-term health and well-being. Connect with Gabriela Rosa: Website: https://fertilitybreakthrough.com/ Facebook: https://www.facebook.com/FertilitySpecialistGabrielaRosa Instagram: https://www.instagram.com/dr.gabrielarosa/ Fertility Breakthrough Instagram: https://www.instagram.com/fertilitybreakthrough/ Fertility Breakthrough Facebook: https://www.facebook.com/rosainstitutefertilitybreakthrough ______________________________ Disclaimer: The information shared on this podcast is for educational and informational purposes only and is not intended as medical advice. Please consult with your healthcare provider before making any changes to your health or fertility care. Ready to discover what your body needs most on your fertility journey? Take the personalized quiz inside The Wholesome Fertility Journey and get tailored resources to meet you exactly where you are: https://www.michelleoravitz.com/the-wholesome-fertility-journey For more about my work and offerings, visit: www.michelleoravitz.com Curious about ancient wisdom for fertility? Grab my book The Way of Fertility: https://www.michelleoravitz.com/thewayoffertility Join the Wholesome Fertility Facebook Group for free resources & community support: https://www.facebook.com/groups/2149554308396504/ Connect with me on social: Instagram: @thewholesomelotusfertilityFacebook: The Wholesome Lotus
Today we welcome Dr. Nancy Miggins Dr Nancy Miggins, DC, ABAAHP, FAAMFM is a double board-certified Doctor of Chiropractic. Her advanced credentials are in Anti-Aging Medicine and Chronic Pain Management. She is also an advanced fellow, completing the prestigious Fellowship in Anti-Aging, Metabolic and Functional Medicine. Dr Miggins has spent over 30 years helping health seekers take the guesswork out of what diet and lifestyle approaches are best for their unique body. Her system, strategies and solutions inspire these individuals to reclaim power over their health and increase their health certainty. She breaks down the science and transforms it into a "why" that motivates action. Her heart-felt compassion and shameless approach inspires an "I can do this" attitude. She promotes a radical gradualism approach to complete health transformation. Get here book here: AMAZON Thank you for your support! The B.I.Stander Podcast is a listener supported podcast so please consider subscribing. BE A FRIEND OF PODCASTVILLE AND TELL A FRIEND Thank you to our very supportive sponsors! Blue Canary Auto Locations in Bainbridge Island & Bremerton Sound Reprographics Locations in Bainbridge Island & Poulsbo Tideland Magazine Pick up a copy on the Ferry Sheldon Orthodontics Free Consultation KitsapSmokestack.org Be your own aligrithom, find what to do in your neighborhood Miguelitos Best Mexican food on the island! 2 great locations on Beautiful Bainbridge Island Editing by: Cherie Newman Magpie Audio Productions Fly on the Wall performed by LeRoy Bell
The 2025-2030 Dietary Guidelines for Americans just dropped, and they represent a major shift from rigid rules to personalized, sustainable nutrition. These aren't just recommendations—they shape what your doctor tells you, influence insurance policies, and determine what's served in schools and hospitals. In this episode, I break down the most important updates and translate them into simple, actionable steps you can implement today. No overwhelm, no perfection required—just practical strategies rooted in the latest research. Tune in to learn the new protein recommendations that could transform your weight loss results, why your cooking method matters more than you think, and which small changes create the biggest health impact over time. --- Sign up for the Back on Track: Setting the Vision for your health Masterclass: https://drshellymd.kit.com/ecc62a0638 Episode Highlights: The new protein target: 1.2-1.6 grams per kilogram body weight (and why it matters for muscle preservation, satiety, and metabolic health) Why cooking methods can sabotage your progress—simple swaps from deep-fried to baked, roasted, or grilled The truth about fats: why healthy fats aren't the enemy and which ones to prioritize Practical carb guidance: focus on fiber-rich whole grains, not elimination Sugar reality check: keeping added sugars under 10 grams per meal Sodium targets and how to actually track your intake The permission to be flexible: mixing plant and animal proteins for variety and nutrition Why progress beats perfection—start with just one or two changes this week Connect with Dr. Alicia Shelly: Website | drshellymd.com Facebook | www.facebook.com/drshellymd Instagram | @drshellymd Linked In | www.linkedin.com/in/drshellymd Twitter | @drshellymd About Dr. Alicia Shelly Dr. Alicia Shelly was raised in Atlanta, GA. She received her Doctorate of Medicine from Case Western Reserve University School of Medicine in Cleveland, OH. Dr. Shelly has been practicing Primary Care and Obesity medicine since 2014. In 2017, she became a Diplomat of the American Board of Obesity Medicine. She is the lead physician at the Wellstar Medical Center Douglasville. She started a weekly podcast & Youtube channel entitled Back on Track: Achieving Healthy Weight loss, where she discusses how to get on track and stay on track with your weight loss journey. She has spoken for numerous local and national organizations, including the Obesity Medicine Association, and the Georgia Chapter of the American Society of Metabolic and Bariatric Surgeons. She has been featured on CNN, Fox 5 News, Bruce St. James Radio show, Upscale magazine, and Shape.com. She was named an honoree of the 2021 Atlanta Business Chronicle's 40 under 40 award. She also is a collaborating author for the, "Made for More: Physician Entrepreneurs who Live Life and Practice Medicine on their own terms''. Resources: FREE! Discover the 5 Reasons Your Weight-Loss Journey Has Gotten Derailed (And How To Get Back On Track!)
Episode 323: You're Not Unmotivated. You're Overloaded.The Thrive Forever Fit Show with Jay NixonIf you've been feeling stuck, overwhelmed, or quietly disconnected from your health journey, this episode is for you.In this training, Jay breaks down a hard truth most people never hear:You're not lazy.You're not unmotivated.You're overloaded.Trying harder isn't the answer when clarity is missing. In this episode, Jay explains why doing “all the right things” often leads to paralysis, frustration, and disengagement—and how simplicity, not intensity, is the key to rebuilding momentum.This is not a hype talk.This is a reset.Whether you've fallen off track or just feel worn down by too many rules, voices, and expectations, this episode will help you exhale, refocus, and re-enter your health journey with confidence and direction.• Why lack of motivation is usually a clarity problem, not a discipline problem• How overload shuts down consistency at the nervous system level• Why success sometimes requires lowering the bar strategically• What “Minimum Effective Standards” really mean for long-term progress• How to rebuild self-trust without starting over• A simple 7-day reset that gets you back into momentum without pressure• Confusion creates paralysis. Simplicity creates momentum• Purpose and progress are revealed through action, not overthinking• You don't need a breakthrough—you need a re-entry point• Momentum returns when pressure is removed• Consistency beats intensity every timeFor the next week, focus on just three things:Move your body 20–30 minutes, three times this weekEat protein at your first meal of the dayGo to bed 30 minutes earlierNo tracking.No perfection.No guilt.If you do these three things, you are back in the game.• Anyone feeling overwhelmed or burned out by their health routine• People who “know what to do” but can't seem to stay consistent• Listeners who feel behind and don't know how to restart• Anyone who needs clarity, not another planMomentum doesn't come from motivation.It comes from direction.And direction starts with one small standard done consistently.
Longevity isn't just about what you eat or how you train—it's really more about whether you believe your body is worth investing in. On this episode of The Dr. Hyman Show, I'm joined by my longtime friend and colleague Dr. Gabrielle Lyon to explore why muscle may be one of the most overlooked drivers of long-term health. We focus on practical, accessible ways to build strength as you age, and why muscle plays a much bigger role in your health than most people realize. We explore: • How strength training supports your blood sugar and metabolic health, beyond what the scale can show • Why muscle quality—not weight—is a stronger predictor of long-term health • How building strength helps you stay mobile, capable, and resilient as you age • What most people miss about protein and muscle health Aging well is something you can actively support, starting with how you care for your body today. And strength is one of the most powerful places you can begin. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman's Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Timeline, PerfectAmino, BIOptimizers, Mau Nui, Made In Cookware and BON CHARGE. Receive 35% off off a subscription at timeline.com/drhyman. Go to bodyhealth.com and use code HYMAN20 to get 20% off your first order. Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%. Learn more about the health benefits of venison and how to get yours, head over to mauinuivenison.com/hyman. Head to madeincookware.com and use the code HYMAN for 10% off your order. Upgrade your routine. Head to boncharge.com/hyman and use code DRMARK for 15% off. (0:00) Introduction and Dr. Gabrielle Lyon's background (1:00) Protein's importance across ages and muscle benefits (3:28) Muscle: A neglected organ and its metabolic roles (8:01) Assessing muscle quality and functional health (13:09) Resistance training and muscle rejuvenation strategies (19:33) Muscle's immune and hormonal functions (22:29) Myokines and body composition analysis (26:17) Strength training and innovative techniques (32:05) Muscle as the organ of longevity and protein's significance (38:12) Dietary guidelines and protein requirement debates (48:08) Amino acids, protein turnover, and intake strategies (59:48) Metabolic flexibility and creatine's benefits (1:00:21) Sponsor: Timeline's research on urolithin A (1:02:20) Mitochondrial health and muscle-centric medicine (1:08:14) Muscle health's mismatch with chronic diseases (1:10:20) Dr. Lyon's longevity practices and quickfire questions (1:16:03) Strength's importance during menopause and cold exposure (1:18:51) Dr. Lyon's career highlights and resources (1:20:17) Closing remarks and disclaimers
Featured on Cancer Breakthroughs 3.0 Summit 2025 — Jane McLelland is a four-time cancer survivor, former Chartered Physiotherapist, and the internationally bestselling author of How to Starve Cancer. After facing stage IV cervical cancer and later treatment-induced myelodysplasia (a pre-leukemia condition), Jane dove into decades of research to decode cancer metabolism and build a practical framework patients and clinicians can understand. Often called a “modern-day Cancer Sherlock Holmes,” she's best known for the McLelland Metro Map™—a visual guide to the fuel pathways cancers use to survive and adapt.In this conversation, Jane explains why cancer is a “shapeshifter” and why single-solution thinking (one drug, one supplement, one diet) often falls short. She breaks down the logic behind her “Metabolic Cocktail” strategy—combining diet, movement, supplements, and carefully selected low-toxicity repurposed drugs to synergistically block multiple cancer fuel routes (glucose, glutamine, and fat pathways). You'll also hear her cautionary take on DIY trends and oversimplified protocols, plus how tools like PET imaging, gene expression insights, and even AI can help personalize a more nuanced, adaptable plan.Most importantly, Jane offers a mindset shift: cancer treatment isn't a static one-time choice—it's an evolving strategy. If you've ever wondered how to “think metabolically,” ask better questions, and understand the why behind integrative combinations (including where keto can help—and where it can backfire), this episode gives you a clearer map and a smarter way forward.Key Topics CoveredWhy cancer behaves like a “shapeshifter” and adapts when one pathway is blockedThe core idea behind the McLelland Metro Map™ and metabolic “fuel routing”Jane's Metabolic Cocktail philosophy: synergy across diet, exercise, supplements, and repurposed drugsThe overlooked role of glutamine and fat metabolism—not just glucose—in cancer fuelingHow keto can help early for some people, and how it may drive resistance pathways later for othersRepurposed drug principles Jane discusses (e.g., metformin-style glucose control, statins, anti-inflammatories, anti-platelet concepts) and why combinations matterUsing tools like PET scans (and the limitations when cancers shift fuels) to understand metabolic activityStrategies and cautions around blocking glutamine uptake (and why receptor-level targeting matters)A practical overview of ferroptosis: GPX4 vs. cysteine/glutathione pathways and why pulsing mattersThe importance of doctor oversight, personalization, and avoiding extreme “one-size-fits-all” DIY protocols -----------------------------------------------A Better Way to Treat Cancer: A Comprehensive Guide to Understanding, Preventing and Most Effectively Treating Our Biggest Health ThreatGrab my book here: https://www.amazon.com/dp/B0CM1KKD9X?ref_=pe_3052080_397514860 Unleashing 10X Power: A Revolutionary Approach to Conquering CancerGet it here: https://store.thekarlfeldtcenter.com/products/unleashing-10x-powerPrice: $24.99100% Off Discount Code: CANCERPODCAST1 Healing Within: Unraveling the Emotional Roots of CancerGet it here: https://store.thekarlfeldtcenter.com/products/healing-withinPrice: $24.99100% Off Discount Code: CANCERPODCAST2-----------------------------------------------Integrative Cancer Solutions was created to instill hope and empowerment. Other people have been where you are right now and have already done the research for you. Listen to their stories and journeys and apply what they learned to achieve similar outcomes as they have, cancer remission and an even more fullness of life than before the diagnosis. Guests will discuss what therapies, supplements, and practitioners they relied on to beat cancer. Once diagnosed, time is of the essence. This podcast will dramatically reduce your learning curve as you search for your own solution to cancer. To learn more about the cutting-edge integrative cancer therapies Dr. Karlfeldt offer at his center, please visit www.TheKarlfeldtCenter.com
Most people assume they're healthy until something breaks. The problem is that dysfunction shows up in your biology years before symptoms appear. I sat down with Dr. Paul Turek to break down what modern biomarkers actually reveal about your health, performance, and long term disease risk. We explore why “normal” lab ranges can be misleading, why guessing based on symptoms fails, and how early signs of metabolic dysfunction, inflammation, and nutrient deficiencies quietly shape how you feel, train, and age. This conversation is about testing and not guessing. We spoke about how to understand what's happening inside your body before problems become diagnosed. And about taking ownership of your health data at any age, not reacting once it's too late. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. Topics discussed.... 00:00 Intro 01:18 Why most people miss early signs of dysfunction 03:42 Why symptoms appear years after biological dysfunction 06:15 What modern blood biomarkers actually reveal about health 09:48 Metabolic dysfunction and early insulin resistance 13:12 Inflammation markers and long-term disease risk 16:30 Why “normal” lab ranges can be misleading 19:55 Nutrient deficiencies that quietly impact energy and cognition 24:05 How biomarkers influence training, recovery, and performance 28:10 Male and female differences in interpreting lab data 32:20 Hormones, aging, and proactive health monitoring 36:05 Why guessing based on symptoms fails 39:45 Taking ownership of your health data at any age 44:05 Longevity, prevention, and performance through testing 48:20 When to test, how often, and what actually matters 52:10 The future of personalized medicine and early intervention 56:00 Final takeaways on testing vs reacting A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Function: Visit https://functionhealth.com/louisa or use gift code NEURO100 at sign-up to own your health. Timeline: Don't let another year go by feeling less than your best. Grab 35% off your one month subscription of Mitopure Gummies at Timeline.com/neuro35 Kion: Support strength, recovery, and muscle as you age with essential amino acids. Get 20% off at https://getkion.com/neuro I'm Louisa Nicola, clinical neurophysiologist, Alzheimer's prevention specialist, and founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain, reducing Alzheimer's risk, and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed.Join thousands who subscribe to the Neuro Athletics Newsletter: https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/theneuroexperience_/ TikTok: https://www.tiktok.com/@louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
If you feel like you're doing everything right and nothing is changing, it's probably not you. It's your metabolism being under supported for years without you even realizing it. In episode 2 of our Real Results Reset series, I'm breaking down why so many women in their 30s, 40s, and 50s feel stuck despite eating clean, moving their bodies, and trying to do all the right things.I walk you through the real metabolic blockers that quietly slow progress, why your body isn't working against you, but protecting you, and what supportive shifts actually help your metabolism respond again without more restriction or burnout.By the end, you'll feel relief knowing your metabolism isn't broken and you're not failing. If you want to find out which blocker is holding you back and what happens when you finally start supporting your body the right way, hit play and let's dive in.4:24 – How Chronic Undereating and Inconsistent Calories Hurt Your Progress7:45 – Why Protein Is The Essential Fix Most Women Miss9:53 – Stress Isn't Just Mental—How Busy Living Spikes Cortisol & Stalls Progress2:57 – Hormonal Shifts in Perimenopause, Menopause, and Postpartum—What They Actually Mean for Metabolism16:57 – Five Simple Steps to Unstick Your Metabolism—Consistency Beats Perfection Every TimeOTHER EPISODES YOU'LL LOVE:Ready to stop starting over? Tune into the Real Results Reset Series playlist and listen to the full January series HERE
A new food pyramid sparked familiar outrage, quick conclusions, and polarized takes across the nutrition industry. This episode isn't about defending or attacking the graphic itself, it's about understanding what population-level guidelines are meant to do, and why they're often misunderstood. Topics discussed: - Population-level nutrition guidance- Food pyramid history- Why guidelines fail- Industry overreaction- Individualized nutrition needs- Coaching versus graphics- Metabolic context matters---------- My Live Program for Coaches: The Functional Nutrition and Metabolism Specialization www.metabolismschool.com---------- [Free] Metabolism School 101: The Video Serieshttp://www.metabolismschool.com/metabolism-101----------Subscribe to My Youtube Channel: https://youtube.com/@sammillerscience?si=s1jcR6Im4GDHbw_1----------Grab a Copy of My New Book - Metabolism Made Simple---------- Stay Connected: Instagram: @sammillerscienceYoutube: SamMillerScience Facebook: The Nutrition Coaching Collaborative CommunityTikTok: @sammillerscience----------“This Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast and the show notes or the reliance on the information provided is to be done at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment and is for educational purposes only. Always consult your physician before beginning any exercise program and users should not disregard, or delay in obtaining, medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. By accessing this Podcast, the listener acknowledges that the entire contents and design of this Podcast, are the property of Oracle Athletic Science LLC, or used by Oracle Athletic Science LLC with permission, and are protected under U.S. and international copyright and trademark laws. Except as otherwise provided herein, users of this Podcast may save and use information contained in the Podcast only for personal or other non-commercial, educational purposes. No other use, including, without limitation, reproduction, retransmission or editing, of this Podcast may be made without the prior written permission of Oracle Athletic Science LLC, which may be requested by contacting the Oracle Athletic Science LLC by email at operations@sammillerscience.com. By accessing this Podcast, the listener acknowledges that Oracle Athletic Science LLC makes no warranty, guarantee, or representation as to the accuracy or sufficiency of the information featured in this Podcast."
The term "ultra-processed food" appeared nearly 100 times in the White House's Make America Healthy Again report. But what if the concept is too imprecise to guide real policy—and could even cause harm?Dr. David Ludwig—Harvard endocrinologist, obesity researcher, and author of Always Hungry—joins Dr. Dominic D'Agostino to dismantle the ultra-processed food framework from the inside out. Ludwig reveals why the NOVA classification system lumps protein bars with soda, why the FDA admitted they can't define what they're trying to regulate, and why the famous studies showing ultra-processed foods cause overeating may be fundamentally flawed.This conversation cuts through the noise to identify what actually matters: the mechanistic difference between processing carbohydrates, fats, and proteins—and why that distinction should reshape nutrition policy.Questions answered in this episode:Can ultra-processed foods be "fixed" through reformulation?What's the most overrated "healthy" food in supermarkets?Should omega-3 levels be part of standard blood work?Are GLP-1 drugs a metabolic reset or a lifelong crutch?If you could pass one food policy law, what would it be?Why did the low-fat diet era make obesity worse?Dr. Ludwig argues that "ultra-processed food" is a compelling marketing term without mechanistic grounding—and that precise, actionable targets like highly processed carbohydrates and demonstrably harmful additives would do far more to improve public health.Special thanks to the sponsors of this episode:✅ Fatty15 – Get 15% off a 90-day Starter Kit with code METABOLICLINK here.✅ Troscriptions – Get 10% off your first order with code METABOLICLINK here.✅ iRestore - Get a huge discount on the iRestore Illumina Face Mask when you use the code METABOLICLINK here.✅Genova Connect – Get 15% off any test kit with code METABOLICLINK here.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
Metabolic health impacts far more than weight — it influences your hormones, inflammation levels, energy, and long-term risk for chronic disease. In this episode of Get Well Better by The Lanby, Taylor Fazio, Wellness Advisor, breaks down what metabolic health really means, why most Americans are metabolically unhealthy, and the everyday habits that can dramatically improve insulin sensitivity and overall health.On this “One Take on One Take” episode:Tip 1: Optimize nutrition by prioritizing fiber, reducing ultra-processed foods, and building balanced meals to support stable blood sugar and reduce inflammation.Tip 2: Build movement into your day — especially strength training — since muscle is one of the most important sites for glucose storage and insulin sensitivity.Tip 3: Use data to personalize your health journey: track key labs (fasting insulin, glucose, HbA1c) and consider a CGM to understand your unique glucose response and improve metabolic flexibility.
The science of metabolic psychiatry is advancing, but the movement behind it is just getting started. In this episode, Dr. Bret Scher sits down with Natasha Smikles and Eddie Rodriguez from Metabolic Collective, a new nonprofit working to build an international advocacy network for ketogenic and metabolic therapies.Their goal: accelerate awareness, adoption, and support for metabolic interventions in mental health.They cover:The personal journeys that led Natasha and Eddie to metabolic therapyWhy lived experience is such a powerful driver of changeWhy Metabolic Collective was created, and who it's forHow Metabolic Collective is organizing community-led advocacy and educationWhat tools, resources, and events are available to help you get involvedHow to support others, start a local group, or bring metabolic psychiatry into your communityMetabolic psychiatry is growing, and movements like this are helping close the gap between research and real-world impact. From mental health challenges to neurological disorders, the Metabolic Collective hopes to spread the word about metabolic therapies and empower patients with alternative options to standard of care.
In this important episode, I break down the newly FDA-approved Wegovy pill and what it means for obesity treatment. The first oral GLP-1 medication for obesity has arrived, offering a needle-free alternative to weekly injections. This development could transform access for patients who've avoided treatment due to injection hesitation, cost barriers, or preference for daily pill routines. Tune in to learn what the Wegovy pill is, how it works, and why it represents a major step forward in giving patients more options for sustainable weight loss. Sign up for the Back on Track: Setting the Vision for your health Masterclass: https://drshellymd.kit.com/ecc62a0638 Episode Highlights: How the Wegovy pill works as a daily medication vs. weekly injections The science behind GLP-1 receptor agonists and appetite regulation Clinical data showing approximately 13.6% body weight reduction Overcoming injection hesitation—a major barrier to treatment adherence Proper dosing: daily pill on empty stomach with specific timing requirements Common side effects and important black box warnings to know Affordable self-pay pricing: starting at $149/month through NovoCare pharmacy program Why more options mean better care for chronic disease management Connect with Dr. Alicia Shelly: Website | drshellymd.com Facebook | www.facebook.com/drshellymd Instagram | @drshellymd Linked In | www.linkedin.com/in/drshellymd Twitter | @drshellymd About Dr. Alicia Shelly Dr. Alicia Shelly was raised in Atlanta, GA. She received her Doctorate of Medicine from Case Western Reserve University School of Medicine in Cleveland, OH. Dr. Shelly has been practicing Primary Care and Obesity medicine since 2014. In 2017, she became a Diplomat of the American Board of Obesity Medicine. She is the lead physician at the Wellstar Medical Center Douglasville. She started a weekly podcast & Youtube channel entitled Back on Track: Achieving Healthy Weight loss, where she discusses how to get on track and stay on track with your weight loss journey. She has spoken for numerous local and national organizations, including the Obesity Medicine Association, and the Georgia Chapter of the American Society of Metabolic and Bariatric Surgeons. She has been featured on CNN, Fox 5 News, Bruce St. James Radio show, Upscale magazine, and Shape.com. She was named an honoree of the 2021 Atlanta Business Chronicle's 40 under 40 award. She also is a collaborating author for the, "Made for More: Physician Entrepreneurs who Live Life and Practice Medicine on their own terms''. Resources: FREE! Discover the 5 Reasons Your Weight-Loss Journey Has Gotten Derailed (And How To Get Back On Track!)
Shawn & Janet Needham R.Ph. have Moira Newiss on the podcast to discuss metabolic mental health. Moira is a BANT registered nutritional therapist, health coach and accredited ketogenic metabolic therapy expert who specializes in brain energy, one of the recently discovered root causes of many mental health problems. Moira supports her clients by helping them understand what is going on with their biology and how to make simple changes in their diet and lifestyle to help address the root cause. She is passionate about offering hope and practical solutions, aiming not only for symptoms to improve, but for clients to get their lives back on track. Moira Newiss Website | https://www.moiranewiss.co.uk/ Facebook | https://www.facebook.com/theenergyrebootexpert/ Instagram | https://www.instagram.com/moiranewiss YouTube | https://www.youtube.com/@moiranewiss Health Solutions Instagram | https://www.instagram.com/health_solutions_shawn_needham/ TikTok | https://www.tiktok.xcom/@healthsolutionspodcast Facebook | https://www.facebook.com/HealthSolutionsPodcast Moses Lake Professional Pharmacy Website | http://mlrx.com.com/ Facebook | https://www.facebook.com/MosesLakeProfessionalPharmacy/ Shawn Needham X| https://x.com/ShawnNeedham2 Shawn's Book | http://mybook.to/Sickened_The_Book Additional Links https://linktr.ee/mlrx
Shalin Shah is the CEO of Marius Pharmaceuticals and widely known as The Metabolic CEO. He's a leading voice in metabolic health and hormone therapy innovation, and one of the strongest advocates working to destigmatize testosterone for both men and women.In this episode, we go deep into what's really happening with testosterone today — why levels are declining across the population, why this is not just a “male” issue, and why testosterone is foundational to metabolic health, longevity, mental health, bone density, and quality of life. Shalin breaks down complex science in a way that's practical and empowering, and explains why testosterone deficiency is being massively underdiagnosed and undertreated.We talk about environmental toxins, sleep disruption, stress, lifestyle, and the long-term consequences of ignoring low testosterone — including cardiovascular disease, diabetes, depression, frailty, and increased all-cause mortality. We also explore the future of hormone therapy, why testing should be standard, and how innovation like oral testosterone could change access and outcomes for millions of people.This conversation is informative, eye-opening, and honestly a bit of a wake-up call — especially for anyone in midlife who wants to age strong, think clearly, and feel energized again.What we cover:Why testosterone levels are declining in men and womenTestosterone as a metabolic health marker, not a lifestyle drugThe role of sleep, stress, toxins, and modern lifeWhy fatigue, brain fog, depression, and low motivation are often hormonalThe truth about testosterone myths and stigmaWhy testing matters — and why baselines should start earlyThe difference between “normal” and “optimal” hormone levelsOral vs topical vs injectable testosteroneWhy muscle, bone health, and longevity are directly tied to hormonesWhat's changing at the FDA — and why this moment mattersPanel: https://www.fda.gov/patients/fda-expert-panels/fda-expert-panel-testosterone-replacement-therapy-men-12102025?Comments: https://www.regulations.gov/document/FDA-2025-N-6743-0001/commentwww.kyzatrex.comhttps://www.instagram.com/themetabolicceo/Please remember to rate, review, and follow the show – and share with a friend!Check out our new Comedy Wellness Podcast: Anything But Mid, cohosted with Whitney Stropp:https://podcasts.apple.com/us/podcast/anything-but-mid/id1849386215https://www.youtube.com/@AnythingButMidFind Amy's affiliates and discount codes: https://amyedwards.info/affiliatepageSky Rock Sedona: https://www.skyrocksedona.com/20% Discount Link:https://www.marriott.com/event-reservations/reservation-link.mi?id=1759866624184&key=CORP&app=resvlinkAll links: amyedwards.infoInstagram: @realamyedwardsFight For Her: fightforher.netTikTok: @themagicbabeYouTube: YouTube ChannelPodcast: The Amy Edwards Show PodcastFree Course: The Ageless MindsetFull Course: The Youthfulness HackWork with Amy: Book a Call Let's get you to your HAPPIEST and most RADIANT! Book a call to apply to work together one-on-one: https://amyedwards.as.me/15mincallAmy's hair by https://www.thecollectiveatx.comPodcast editing by https://podcastmagician.com/Get my FREE course "The Ageless Mindset: The Ultimate Guide to Look Younger and Feel Happier!" HERE: https://best-you-life.teachable.com/p/the-ageless-mindset-the-ultimate-guide-to-look-younger-feel-happierGet the full course “The Youthfulness Hack: The Secret System to Reverse Aging Fast and Create a New, Radiant You!” Out now! https://best-you-life.teachable.com/p/the-youthfulness-hack
Send us a textFeeling “fine” with normal labs can hide the earliest signs of metabolic trouble. We dive into a revealing study of young adults that compares sedentary people to those who simply meet activity guidelines, and what it uncovers inside their muscle cells is hard to ignore: lower mitochondrial respiration, poorer cardiolipin quality, higher lactate production, and a tilt toward glycolysis that predicts insulin resistance and chronic disease years before a diagnosis.We walk through why mitochondria—not BMI or a single glucose reading—are the real engines of health. You'll hear how cardiolipin acts like high‑grade motor oil for the electron transport chain, what happens when its quality drops, and why consistent moderate movement upgrades both the quantity and the integrity of this critical lipid. The active group in the study wasn't elite; they just hit 150 minutes of weekly activity, yet showed superior fat oxidation, better lactate handling, and true metabolic flexibility.We also connect the dots to food. With the dietary guidelines flipping the old pyramid, we talk about prioritizing whole foods, quality protein, whole‑fat dairy, eggs, fish, and minimizing refined grains to support resilient cell membranes and healthier mitochondria. Pair that with practical steps—brisk walking most days, a bit of resistance training, and paying attention to deeper markers like fasting insulin or HOMA‑IR—and you have a blueprint to improve energy, reduce cravings, and lower long‑term risk without chasing extreme routines.If you've been waiting for a sign to start moving and simplify your plate, this is it. Subscribe, share with someone you love, and leave a review to tell us the one change you'll make this week. Your cells will notice first—and the rest of your life will follow.For video, open source references and PowerPoint slide deck: www.thehealthedgepodcast.com
Leg weakness, burning when walking, wobbling knees, or foot pain are not signs of aging. They are often early warnings of insulin resistance and metabolic dysfunction, which silently damages muscle, nerves, and circulation long before diabetes is diagnosed. Your legs are meant to be the body's largest blood sugar sponge. When insulin resistance develops, glucose cannot enter muscle cells efficiently, leading to muscle fatigue, inflammation, fat infiltration, nerve damage, and poor circulation. Common warning signs include: Heavy or tired legs while walking Burning or cramping muscles Balance issues and slower gait Difficulty standing from a chair Tingling, numbness, or cold feet Key labs that reveal the problem: Fasting insulin (optimal: 3–6) HbA1c (optimal: 5.2% or lower) Fasting glucose (70–90 mg/dL) Triglycerides under 100 HDL over 60 Triglyceride-to-HDL ratio under 1.5 The 7-step protocol to restore leg strength: Stop eating at least 3 hours before bed Strength train legs twice per week Eat 30–40g of high-quality protein per meal Lower carbs, eliminate snacking, and walk after meals Walk daily to improve circulation Support nerves with sleep, B vitamins, grounding, and red light therapy Prioritize deep, consistent sleep Ben emphasizes that leg strength is metabolic protection, not vanity, and that fixing insulin resistance can rapidly restore strength, balance, and energy.
On this episode of The Dr. Hyman Show, I'm rejoined by psychiatrist and Harvard professor Dr. Chris Palmer for a conversation that challenges how we've been taught to think about mental illness. For decades, psychiatry has focused on managing symptoms—often without asking what's actually driving them. We discuss a different way of understanding mental health, one that looks beyond diagnostic labels and considers how whole-body biology influences brain function, resilience, and recovery. Watch the full conversation on YouTube or listen wherever you get your podcasts. In this conversation, we explore: • Why mental illness is rising alongside obesity, diabetes, and other chronic diseases • How whole-body biology influences mood, focus, and emotional resilience • The link between inflammation, metabolic dysfunction, and conditions like depression and bipolar disorder • How nutrition, testing, and lifestyle changes can support real recovery If mental health has ever felt close to home for you or someone you care about, this conversation is meant to offer clarity, compassion, and a place to start. This episode was recorded live at the Eudēmonia Summit, a conference exploring the future of health, longevity, and well-being. Learn more at eudemonia.net. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hymanhttps://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman's Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Timeline, BON CHARGE, Qualia, Paleovalley, Pique and Korrus. Receive 35% off a subscription at timeline.com/drhyman. Upgrade your routine. Head to boncharge.com/hyman and use code DRMARK for 15% off. Go to qualialife.com/hyman and use code HYMAN at checkout for an extra 15% off. Head to paleovalley.com and use code HYMAN20 for 20% off your first order. Secure 20% off your order plus a free starter kit at piquelife.com/hyman.Upgrade your lighting. Enjoy 15% off at korrus.com/drhyman. (0:00) Introduction to mental health crisis and guest Dr. Christopher Palmer (1:31) Eudaimonia Summit and psychiatric revolution (3:06) Traditional and systemic views on psychiatric disorders (7:23) Misconceptions and stigma surrounding mental disorders (10:15) The impact of childhood experiences on mental health (13:28) Root causes of mental illness: Inflammation and brain dysfunction (21:23) Metabolic dysfunction in mental illness (24:15) Significance of metabolism in mental health (27:47) Metabolic nutritional psychiatry and premature mortality (32:34) The mental health revolution and metabolic treatments (34:16) Ketogenic diet as a potential treatment for mental disorders (37:18) Functional and network medicine in mental health (41:13) Biomarkers and potential treatments in metabolic mental health (49:07) Ketogenic therapy and its anti-inflammatory effects (50:12) Historical and emerging paradigms in psychiatry (54:38) Integrating functional medicine into mainstream psychiatry (56:20) Addressing chronic disease in national health discussions (58:22) Closing remarks and further resources (59:02) Podcast outro and call to action
Your physiology doesn't always follow what the textbooks say. In this episode, we sit down with Dr. Marco Altini (ultra runner, endurance coach, data scientist, and thinker at the intersection of physiology, technology, and performance). Marco opens up about the moment he realized that doing the same high-carb diet he recommended to himself for years wasn't actually working as well as he thought. He walks us through how shifting to a periodized approach - changing fueling based on training demands rather than sticking to a fixed carb ratio - improved his fat oxidation, gut health, and performance markers in ways he hadn't seen before. Marco grounds the discussion in real data, including how his substrate oxidation changed after adjusting his diet and why better metabolic flexibility matters for endurance athletes. Along the way, we tackle common misconceptions about high-carb diets, the link between GI distress and fueling strategy, and why testing beats guessing when you want to understand your own response to food and training.What we cover in this episode:Why metabolic efficiency is not a single target, but a moving rangeHow nutrition periodization can support training without wrecking your gutThe overlooked connection between GI distress and everyday dietary patternsWhat Marco learned from tracking substrate oxidation instead of guessingHow fat oxidation and VO₂-related metrics can change with nutrition shiftsWhy weight loss is not the same thing as improved performanceThe role of testing in understanding what your body actually responds toHow to think critically about fueling without copying elite or influencer strategiesLinks:Follow Dr. Altini's Substack and find him on Instagram @altini_marcoMarco's Substack article "Periodized Nutrition and Metabolic Flexbility for Endurance Performance"Marco's Substack article "Learnings from a Year of Periodized Nutrition and Metabolic Testing"Bob's Metabolic Efficiency Training book (3rd edition)More about our guest: Marco holds a PhD cum laude in applied machine learning, a M.Sc. cum laude in computer science engineering, and a M.Sc. cum laude in human movement sciences and high-performance coaching. He has published more than 50 papers and patents at the intersection between physiology, health, technology and human performance. He is the co-founder of HRV4Training, Endurance Coach at Destination Unknown, advisor at Oura, guest lecturer at VU Amsterdam, and editor of the Wearables department of IEEE Pervasive Computing. He loves running.Download the Patreon app to join our free Community (@isnpodcast) and become a supporter of the show by joining our low-cost Silver or Gold level membership. -------Subscribe to our show to get the weekly episodes and also check out the YouTube channel.You can help us remain 100% ad-free and get access to exclusive bonus content and behind-the-scenes conversations with Bob and Dina. Join our Patreon community or find us in the Patreon app by searching ISNPodcast.We'd love to connect with you on Instagram @isnpodcast and on Facebook @insidesportsnutrition And when you're ready to level up your health and performance even more, check out the services offered by Bob and Dina at their respective businesses.
Essential Wellness Podcast This week on the Essential Wellness Podcast, our community gathered for the official kickoff call of the 90-Day Wellness Reset Program, hosted by Aisha Harley and guided by Dr. Josie Schmidt and Dr. Louise Rose. This foundational call set the tone for the next three months, introducing a gentle, sustainable approach to detoxification and whole-body wellness. Unlike short-term cleanses, this reset is designed to work with the body—supporting natural detox pathways through preparation, nourishment, and intentional daily practices. Participants were encouraged to approach the journey with curiosity, patience, and an open mind as they begin this transformational reset together.
Are you training hard, eating clean… yet still not seeing fat loss or performance improvements? Today, metabolic testing expert Daniel Crumback joins me to explain how metabolic testing helps you finally stop guessing and start personalizing your training, nutrition, and recovery based on real physiology. We break down exactly what we measure in a Resting Metabolic Rate test and an Active VO₂ Peak test — including fat vs. carb utilization, metabolic flexibility, ventilatory thresholds (VT1 & VT2), FatMax, VO₂ peak vs. max, and heart-rate zones based on your actual data, not formulas. You'll learn how to: • Improve fat burning at rest and during exercise • Identify breathing, cardiac, or metabolic limitations • Train smarter with accurate Zone 2, tempo, and interval zones • Support longevity and mitochondrial health • Adapt training for midlife hormones and stress load Daniel and I also share the most common mistakes people make before and after testing — and how getting your physiology right can transform your results. If you're stuck doing "all the right things" with no payoff, this episode will show you the missing data your body has been trying to tell you. Learn more about Daniel: https://strategichealthperformance.com/about-me-final/ Connect with Debbie: www.debbiepotts.net Educational only. Partner with a qualified practitioner—especially if you're on medications, have gallbladder disease, significant anemia, active IBD, are pregnant, or have complex conditions.
Doug Reynolds thought he was bulletproof until his running career collapsed under mysterious weight gain and joint pain. Three weeks studying ketones changed everything—launching Low Carb USA and the Society of Metabolic Health Practitioners. What emerged wasn't just conferences but sanctuary for practitioners facing hostility from colleagues who resist dietary intervention. Reynolds breaks conventional barriers: speakers scatter among attendees, forging relationships that span the country. After a three-year battle, the Society now offers ACCME-accredited continuing education credits, legitimizing metabolic medicine. January 23-25, 2026 conference at lowcarbusa.org. Code IFIXHEARTS saves 20%.BIG IDEAThe loneliness of practitioners who face hostility for recommending dietary interventions has created an urgent need for community—and Low Carb USA became that refuge by accident, simply by bringing people together in the same room.Doug Reynolds Contact InfoSociety of Metabolic Health Practitioners: https://thesmhp.org/Low Carb USA: https://www.lowcarbusa.org/The Road to Metabolic Health: https://amzn.to/4qtEPpESend Dr. Ovadia a Text Message. (If you want a response, you must include your contact information.) Dr. Ovadia cannot respond here. To contact his team, please send an email to team@ifixhearts.com Like what you hear? Head over to IFixHearts.com/book to grab a copy of my book, Stay Off My Operating Table. Ready to go deeper? Talk to someone from my team at IFixHearts.com/talk.Stay Off My Operating Table on X: Dr. Ovadia: @iFixHearts Jack Heald: @JackHeald5 Learn more: Stay Off My Operating Table on Amazon Take Dr. Ovadia's metabolic health quiz: iFixHearts Dr. Ovadia's website: Ovadia Heart Health Jack Heald's website: CultYourBrand.com Theme Song : Rage AgainstWritten & Performed by Logan Gritton & Colin Gailey(c) 2016 Mercury Retro RecordingsAny use of this intellectual property for text and data mining or computational analysis including as training material for artificial intelligence systems is strictly prohibited without express written consent from Dr. Philip Ovadia.
Warrior woman — if you're training consistently, eating “pretty well,” doing the steps, doing the protein… and your bod still isn't shifting the way you expected — this episode is for you girl. Because this isn't an age problem. It's not a hormones problem. And it's definitely not a motivation problem. It's a strategy and sequence problem. Body composition is an adaptation. And adaptations have prerequisites. Most women were taught the what… but not the when, the why, or the context. So you end up executing “the right things” inside a system that can't support the outcome you're asking for. In this episode, I'm teaching you how to think like a strategist:strategy → systems → sequencing — and why your bod adapts when the inputs finally make sense in the right order. What You'll Learn in This Episode If you've been stuck in that loop of “I'm doing everything… why isn't this working?” we're unpacking: What strategy actually is (and why it's not just a plan) Why your body responds to context not effort The difference between a goal and a strategy The “Warrior System Stack”: the 4 layers you can't skip if you want results Why you're chasing the outcome your system isn't ready to support How to find the one system that's currently limiting your progress What to do next if you want body recomposition (without forcing it) Key Takeaways (Strategy, Systems + Sequencing) 1) Body composition is an adaptation — and adaptations require prerequisites 2) You were taught the what**… not the** order 3) Your strategy fails when it ignores the system you're operating inside 4) The Warrior System Stack Layer 1: Nervous system (safety, capacity, resiliency) Layer 2: Metabolic system (energy availability, consistency) Layer 3: Mechanical system (movement, load tolerance, joints/tissues) Layer 4: Adaptation (intensity + expression — where body comp happens) 5) Sequence beats intensity 6) If nothing is changing, it's not because your body is stubborn — it's because she's intelligent 7) Ask these 3 questions to find your next move Which system is limiting me right now? (nervous / metabolic / mechanical) Am I trying to force an adaptation I haven't prepared for? What's the next stabilizing action I can repeat for 30 days? Powerful Quotes “Your body doesn't respond to effort alone. She responds to context — to systems — to order.” “This is not an age problem. This is not a hormone problem. It's a strategy and sequence problem.” “Body recomposition is an adaptation — and adaptations require prerequisites.” “You're doing a lot of the right things… but in the wrong era of your body and your life.” “If you skip the order, your body doesn't adapt — not because she's stubborn, but because she's intelligent.” BUILD THE BODY YOU LOVE TRAINING ASSESSMENT WORKSHOP If you want to build a body you love… you have to know where you're actually at. Girl… you're doing so many of the right things. The lifting, the walking, the fuelling — you're trying. But if you don't know where you're actually at in your training — what's working, what's missing, what your body needs right now — it's almost impossible to move forward. That's why I'm hosting a small, private workshop on JAN 30th We're going to slow everything down and look at your training clearly so you finally know what to focus on — and why. This workshop gives you a proven pathway and the exact next steps you need to finally move forward — now and in the next six months. Because: You can't build the body you love if you don't know where you're really at. Save your seat and get your Training Assessment — https://warriorschool.co/training-assessment/ Listen + Subscribe If you've been stuck doing “all the right things” and wondering why your body isn't changing — this episode will give you the missing piece: order. Press play now, and if this hits, subscribe so you don't miss what's coming next inside Warrior School Pod.
Dr. Jenn Simmons joins the Biohacker Babes for a powerful and deeply personal conversation about her shift from conventional oncology to functional medicine after witnessing the impact of breast cancer in her own family. She pulls back the curtain on the limitations of traditional cancer care — especially the overreliance on mammograms — and explains why true prevention begins with metabolic health, lifestyle choices, informed patient advocacy, and other options for testing. Dr. Jenn challenges the profit-driven structure of the healthcare system and empowers listeners to question standard protocols, explore more predictive screening options like the Auria test, and reclaim responsibility for their wellbeing. This episode is a bold call to action for anyone ready to move beyond fear-based medicine and step into proactive, root-cause healing.Dr. Jenn Simmons is a breast surgeon, integrative oncologist, best-selling author, Podcast Host, 3x Summit host and founder of PerfeQtion Imaging. She began her career as Philadelphia's first fellowship-trained breast surgeon and spent 17 years at the forefront of breast oncology.Her own health crisis led her to discover functional medicine and a new framework for patient care—one focused on creating health rather than managing disease. In 2019, she left conventional medicine to establish Real Health MD, where she helps women on their breast cancer journey truly heal.Today, her mission is to transform the landscape of breast cancer detection and survivorship. Through innovations in functional imaging, hormone restoration, and integrative care, Dr. Simmons aims to revolutionize how we screen for breast cancer and to redefine longevity for all women, including those with a history of breast cancer.SHOW NOTES:0:40 Welcome to the podcast!2:06 About Dr. Jenn Simmons3:02 Welcome Dr. Jenn to the show!3:46 Her turning point from conventional care7:26 Dr. Mark Hyman & functional medicine9:45 Conventional whack-a-mole17:26 Dad's transition into Biological Dentistry20:19 Metabolic chaos in children23:45 Cholesterol & metabolic health32:25 Mammograms & radiation35:55 History & stats on mammography43:02 We all make cancer cells44:27 Diagnosis mindset46:33 Renee's screening53:28 Alternative screening options58:39 Perfeqtion Imaging centers1:00:04 The Galleri Test1:07:48 Changing the system1:10:24 Where to find her1:11:49 Her final piece of advice1:12:50 Thanks for tuning in!RESOURCES:Website: www.perfeqtionimaging.com, www.realhealthmd.comYouTube: @dr.jennsimmonsIG: @drjennsimmons Auria Tears Test - code: DRJENN20Support this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands
In this eye-opening episode, we explore one of the most exciting shifts in modern mental health: the discovery that mental health is deeply rooted in metabolic health. When the brain's energy supply falters, everything from mood to memory to emotional resilience can be affected — and new research is revealing how nutrition and lifestyle can restore balance. Our guest, Moira Newiss, is a BANT-registered nutritional therapist, health coach, and accredited ketogenic metabolic therapy expert who specializes in brain energy — a newly recognized root cause of many mental health challenges. Moira helps clients understand what's happening in their biology and guides them through simple, practical changes that spark real transformation. Her work is grounded in hope, clarity, and the belief that people can not only feel better but truly get their lives back on track. Together, we unpack how ketogenic diets can provide a cleaner, more efficient fuel source for the brain through ketones, helping stabilize brain energy and improve mental well-being. Moira also explains why diet is only one piece of the puzzle — and how sleep, light, movement, and stress balance each play essential roles in optimizing brain metabolism. Want to watch this episode on YouTube? Click here. Subscribe if you'd like to catch all new episodes live and participate with our guests directly. Want to learn more about becoming an FDN? Go to fdntraining.com/resources to get our best free workshops and mini-courses! Where to find Moira Newiss: Website: moiranewiss.co.uk Instagram: @moiranewiss YouTube: @moiranewiss
If you've fallen off your weight loss journey—whether from illness, the holidays, or life's unexpected turns—this episode will help you start moving forward again. I'm opening up about my own 2025 health crisis: developing blood clots in both lungs that stopped me in my tracks physically and emotionally. After significant weight gain and struggling to walk a mile that once took me 12 minutes, I'm sharing the hard-won lessons from rebuilding my fitness from scratch. In this episode, I tackle the mental and physical challenges of restarting when you're nowhere near where you used to be. Whether you're getting back on track after illness, holidays, or just feeling stuck, I walk you through three practical strategies that helped me go from exhausted after one walk to running comfortably again. Episode Highlights: How serious illness can derail both fitness and self-worth Why your inner dialogue matters more than you think during setbacks Three actionable strategies for resetting your weight loss journey The power of scheduling workouts and building accountability Dr. Shelly's 2026 fitness goals: Olympic triathlon, Mount Kilimanjaro, and Berlin Marathon Why flexibility and grace are essential when life throws you off course Upcoming vision workshop on January 15th at 7pm EST Connect with Dr. Alicia Shelly: Website | drshellymd.com Facebook | www.facebook.com/drshellymd Instagram | @drshellymd Linked In | www.linkedin.com/in/drshellymd Twitter | @drshellymd About Dr. Alicia Shelly Dr. Alicia Shelly was raised in Atlanta, GA. She received her Doctorate of Medicine from Case Western Reserve University School of Medicine in Cleveland, OH. Dr. Shelly has been practicing Primary Care and Obesity medicine since 2014. In 2017, she became a Diplomat of the American Board of Obesity Medicine. She is the lead physician at the Wellstar Medical Center Douglasville. She started a weekly podcast & Youtube channel entitled Back on Track: Achieving Healthy Weight loss, where she discusses how to get on track and stay on track with your weight loss journey. She has spoken for numerous local and national organizations, including the Obesity Medicine Association, and the Georgia Chapter of the American Society of Metabolic and Bariatric Surgeons. She has been featured on CNN, Fox 5 News, Bruce St. James Radio show, Upscale magazine, and Shape.com. She was named an honoree of the 2021 Atlanta Business Chronicle's 40 under 40 award. She also is a collaborating author for the, "Made for More: Physician Entrepreneurs who Live Life and Practice Medicine on their own terms''. Resources: FREE! Discover the 5 Reasons Your Weight-Loss Journey Has Gotten Derailed (And How To Get Back On Track!)
In this episode, Dr. Tony Ebel addresses a question that deeply concerns seizure parents: why seizures often increase during developmental leaps. Drawing from both clinical experience and his personal journey as a father, he explains how these temporary upticks can be part of neurological growth and healing, not necessarily regression. Dr. Tony breaks down the neuroscience behind neuroplasticity, increased metabolic demand, and why the nervous system can look more unstable before reorganizing more effectively. He also shares clear guidance on how to support your child during these phases, how to tell the difference between healing progress and true setbacks, and when additional medical support is needed.-----Links & ResourcesListen to the deep dive seizures episode here.Get access to our free guide to improve your child's sleep here.-----Key Topics Covered:3:00 Dr. Tony's personal story and his son's seizure journey6:00 Reframing the challenge and when an uptick may signal healing11:00 The neuroscience of neuroplasticity and temporary instability14:00 Why vulnerable nervous systems struggle more during developmental leaps17:00 Three key signs to distinguish healing progression from true regression22:00 How parents can support their child through regulation, sleep, and metabolic needs26:00 Metabolic demand and the immune system connection30:00 The vagus nerve's role in neurological stability32:00 Understanding regression as part of progression in healing36:00 Practical recap and warning signs that require medical review40:00 Closing encouragement and how to submit future questions-- Follow us on Socials: Instagram: @pxdocs Facebook: Dr. Tony Ebel & The PX Docs Network Youtube: The PX Docs For more information, visit PXDocs.com to read informative articles about the power of Neurologically-Focused Chiropractic Care. Find a PX Doc Office near me: PX DOCS DirectoryTo watch Dr. Tony's 30 min Perfect Storm Webinar: Click Here
Have you ever said, "I just don't feel like myself anymore" — even though your labs look normal? In this episode of the Health Fix Podcast, Dr. Jannine Krause breaks down why inflammation starts in the brain, how it drives fatigue, brain fog, cravings, hormone imbalance, and accelerated aging — and why 2026 is the year to stop suppressing symptoms and start correcting root causes. Inflammation isn't just a body problem. It's a brain health issue first. Your brain uses 20% of your daily calories, and when inflammation is present, it shifts into defensive mode, not performance mode. That's when clarity disappears, energy crashes, and nothing feels like it's working anymore.
Amanda King ND is a nutritional therapist, naturopathic practitioner, and author of Metabolic Drugs for Cancer (co-written with Dr. Hari Kuhan). She also writes The Metabolic Nutritionist on Substack—followed by 30,000+ subscribers—where she breaks down off-label oncology drugs, supplements, and metabolic approaches to cancer care in clear, practical language. In this episode, Dr. King joins Dr. Michael Karlfeldt to explain why “cancer is a disease of metabolism” is more than a slogan—and how understanding metabolic weaknesses can empower smarter, more personalized integrative strategies.You'll hear how repurposed medications can target cancer's metabolic pathways (glucose, mitochondria, inflammatory signaling, and more), and why personalization matters more than internet protocols. Amanda and Dr. Karlfeldt discuss the Care Oncology “METRICS” drug set (including metformin, statins, doxycycline, and mebendazole), plus additional tools like ivermectin, fenbendazole, DCA, 2-DG, anti-inflammatories (aspirin/COX pathways), histamine blockers (cimetidine), and even PDE5 inhibitors like sildenafil/tadalafil—along with real cautions around dosing, contraindications, and interactions (including potential conflicts with immunotherapy). The conversation also ties metabolic therapy to the “press–pulse” concept and terrain-based care: ketogenic nutrition, inflammation reduction, oxygenation, and lifestyle foundations that strengthen the body while making cancer more vulnerable.Whether you're a patient, caregiver, or practitioner, this episode offers a grounded roadmap for thinking about integrative oncology without guesswork—using a “test, assess, address” mindset to build a strategy that evolves with labs, symptoms, treatment phases, and the individual.Key Topics Covered (bulleted)Why cancer metabolism (not just genetics) is a key lever in integrative oncologyWhat repurposed/off-label drugs can target: glucose pathways, mitochondria, signaling pathways (e.g., EGFR/AKT/mTOR)Why one-size-fits-all protocols are risky—and how to personalize using “test, assess, address”The Care Oncology/METRICS drug set and when it may (or may not) fitSafety and dosing concerns with high-dose ivermectin/fenbendazole and DIY internet protocolsWhen metformin vs berberine may be appropriate—and why they can sometimes be combinedDoxycycline: potential synergy (e.g., with IV vitamin C) vs contraindications (including immunotherapy concerns)Anti-inflammatory strategy: COX pathways, aspirin vs selective COX-2 approaches, plus natural options“Press–pulse” metabolic strategy and why protocols should evolve over timeOther emerging tools discussed: DCA, 2-DG, cimetidine, itraconazole, PDE5 inhibitors (Viagra/Cialis) -----------------------------------------------A Better Way to Treat Cancer: A Comprehensive Guide to Understanding, Preventing and Most Effectively Treating Our Biggest Health ThreatGrab my book here: https://www.amazon.com/dp/B0CM1KKD9X?ref_=pe_3052080_397514860 Unleashing 10X Power: A Revolutionary Approach to Conquering CancerGet it here: https://store.thekarlfeldtcenter.com/products/unleashing-10x-powerPrice: $24.99100% Off Discount Code: CANCERPODCAST1 Healing Within: Unraveling the Emotional Roots of CancerGet it here: https://store.thekarlfeldtcenter.com/products/healing-withinPrice: $24.99100% Off Discount Code: CANCERPODCAST2-----------------------------------------------Integrative Cancer Solutions was created to instill hope and empowerment. Other people have been where you are right now and have already done the research for you. Listen to their stories and journeys and apply what they learned to achieve similar outcomes as they have, cancer remission and an even more fullness of life than before the diagnosis. Guests will discuss what therapies, supplements, and practitioners they relied on to beat cancer. Once diagnosed, time is of the essence. This podcast will dramatically reduce your learning curve as you search for your own solution to cancer. To learn more about the cutting-edge integrative cancer therapies Dr. Karlfeldt offer at his center, please visit www.TheKarlfeldtCenter.com
In this episode, Dr. Derrick Hines sits down with Renée Fitton, MS, RD, to explore the science behind fasting-mimicking diets and how short, structured fasting cycles can reset metabolism, reduce inflammation, and support long-term health.They break down how fasting-mimicking protocols activate cellular repair processes like autophagy, improve insulin sensitivity, reduce visceral and liver fat, and support longevity without extreme restriction or muscle loss. The conversation also covers emerging research on diabetes reversal, inflammation reduction, and how fasting-mimicking diets may support cancer care and healthy aging.This episode offers a clear, practical look at how using food strategically — not constantly — can help restore metabolic flexibility and improve overall health.Topics Covered:- How fasting-mimicking diets work at a cellular level- Metabolic reset, insulin sensitivity, and inflammation reduction- Visceral fat, liver health, and biological aging- The role of fasting-mimicking diets in diabetes and longevity- Emerging research on cancer support and immune resilience- Why short, periodic fasting can be more effective than daily restriction
Sunlight is a vital sign for human health. In this episode, we explore the science-backed benefits of sunlight beyond vitamin D...including hormone balance, circadian rhythm, fertility, mood, metabolism, and immune health. We will also cover how to safely personalize sun exposure based on skin tone, timing, and lifestyle.-----
In this powerful interview, Shana sits down with Sam Hughes, VP of Sales at Unicity, to uncover the story and science behind the Feel Great System—a metabolic support protocol built on two potent products: Unimate and Balance. Sam shares his unique journey from working in customer service to helping roll out this system across North America. He breaks down the ingredients inside each product, why they were chosen, and how they're helping thousands reverse insulin resistance, balance blood sugar, and feel better—often fast. If you're ready to simplify your wellness journey and actually feel great, this episode is for you. What We Cover in This Episode Sam's journey from customer service to VP of Sales at Unicity How the Feel Great System was developed—and why it's so effective Ingredient breakdown: Unimate: Yerba mate extract, chlorogenic acid, mood + fat metabolism Balance: Biosphere fiber matrix, insulin + cholesterol control Success stories from the field Why metabolic health is in crisis (and what's working) How to integrate these nutraceuticals with fasting and circadian health strategies
Glioblastoma has a long-term survival rate under 1% at ten years. After decades of research focusing primarily on mutation-targeted therapies, median survival has improved by only a few months. Dr. Tomás Duraj believes there's a better path forward.Dr. Duraj is a physician-scientist at Boston College working on the metabolic vulnerabilities of cancer. In this Metabolic Health Summit presentation, he outlines a clinical framework for studying ketogenic metabolic therapy — one built on biomarker-driven protocols, not dietary guesswork.The core argument: cancer cells depend on specific metabolic pathways for survival. Block those pathways while providing alternative fuels to healthy cells, and you create a therapeutic window that most tumors can't escape.Why cancer cells metabolically resemble organisms from 2 billion years agoThe limits of the somatic mutation theory and why most targeted gene therapies have underdeliveredSubstrate level phosphorylation vs. oxidative phosphorylation — and why the distinction mattersThe Glucose-Ketone Index as a measurable, actionable biomarkerThe press-pulse strategy: sustained metabolic pressure paired with targeted interventionsHow to protect healthy tissue before targeting tumor metabolismRepurposed pharmacological approaches and the need for publicly funded clinical trialsThe case for small, non-randomized pilot studies with highly motivated patientsMetabolic therapy represents the future of medicine: a coherent clinical strategy grounded in decades of research and increasingly recognized by physicians and scientists across disciplines. For practitioners seeking complementary approaches that extend the reach of oncological therapeutics, this presentation lays out a practical roadmap for integrating emerging insights with standard care.✅Genova Connect – Get 15% off any test kit with code METABOLICLINK here.✅ iRestore - Get a huge discount on the iRestore Illumina Face Mask when you use the code METABOLICLINK here.✅Piquelife.com - Get the Pu'er Bundle for 20% off here.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
In this episode of The Lisa Fischer Said Podcast, Lisa Fischer sits down with Reed Davis, founder of Functional Diagnostic Nutrition (FDN), to challenge everything you think you know about functional medicine and "root cause" healing. Reed shares his journey from environmental law to health detective, explains why symptoms are not the problem—but signals of deeper metabolic chaos—and breaks down his HIDDEN and D.R.E.S.S. frameworks for restoring health without drugs. They dive into functional lab testing, supplement skepticism, thyroid disorders, chronic fatigue, hives, ADHD, environmental toxins, and why personalized, upstream investigation matters more than diagnoses. This conversation is a must-listen for anyone frustrated with normal labs, endless prescriptions, or one-size-fits-all wellness advice. WEBSITE: https://www.functionaldiagnosticnutrition.com/ INSTAGRAM: https://www.instagram.com/fdntraining/ FACEBOOK: https://www.facebook.com/FunctionalDiagnosticNutrition/ YOUTUBE: https://www.youtube.com/channel/UC7xDnEKCe9gKeWZ2vbE3C8w EPISODE SPONSOR: https://www.ralstonfamilyfarms.com/ EPISODE SPONSOR: https://www.akelscarpetone.com/ EPISODE SPONSOR: https://www.davidsburgers.com/ LISA'S LINKS: Lisa Fischer Said Academy: https://lisafischersaid.com/academy/ Website: lisafischersaid.com For more information on group intermittent fasting coaching with Lisa, email fasting@lisafischersaid.com For more information on one-on-one or group health coaching with Lisa, email healthcoaching@lisafischersaid.com Podcast produced by clantoncreative.com
In episode #412 of The Hormone Puzzle Podcast, our host, Dr. Kela Smith, talks about Peptides 101: What They Are, How They Work, and Why They're Transforming Metabolic, Hormone & Wellness Optimization – Inside the Fertility Puzzle with Dr. Kela. At the end of every month on The Hormone Puzzle Podcast, Dr. Kela takes you Inside the Fertility Puzzle with a special solo episode dedicated to key fertility topics. From optimizing hormones and decoding lab results to fostering emotional resilience, these episodes deliver actionable advice and expert insights to support your journey to conception. Designed to equip you with the tools and knowledge needed to navigate your unique fertility challenges, this series is your guide to empowerment and clarity. Tune in and let's work together to solve your fertility puzzle with confidence! More about Dr. Kela: Dr. Kela Smith is a leading Holistic Integrative Fertility & Hormone Doctor, dedicated to supporting women and couples facing fertility challenges. After overcoming her own fertility struggles using the Hormone Puzzle Method, it has been her mission to help others solve their infertility puzzles so they can get and stay pregnant, have a healthy happy pregnancy, and easy postpartum. An accomplished author, she also hosts Solving-Infertility Summit, and Healthy Happy Pregnancy Summit. Dr. Kela's expertise also extends to guiding and inspiring future fertility experts as the lead educator at the Hormone Puzzle Society Educational Institute. Thank you for listening! This episode is brought to you in partnership with Proov - https://proovtest.com/PUZZLE Follow Dr. Kela on Instagram: @kela_healthcoach Get your FREE Fertility Meal Plan: https://hormonepuzzlesociety.com/ FTC Affiliate Disclaimer: The disclosure that follows is intended to fully comply with the Federal Trade Commission's policy of the United States that requires to be transparent about any and all affiliate relations the Company may have on this show. You should assume that some of the product mentions and discount codes given are "affiliate links", a link with a special tracking code This means that if you use one of these codes and purchase the item, the Company may receive an affiliate commission. This is a legitimate way to monetize and pay for the operation of the Website, podcast, and operations and the Company gladly reveals its affiliate relationships to you. The price of the item is the same whether it is an affiliate link or not. Regardless, the Company only recommends products or services the Company believes will add value to its users. The Hormone Puzzle Society and Dr. Kela will receive up to 30% affiliate commission depending on the product that is sponsored on the show. For sponsorship opportunities, email HPS Media at media@hormonepuzzlesociety.com
Early signs of brain damage linked to obesity are already showing up in young adults, decades before symptoms like memory loss or confusion begin Having low levels of choline, a nutrient most people don't get enough of, is strongly connected to inflammation, liver stress, and neuron injury in people with obesity Women are especially vulnerable to brain-related effects of metabolic stress, as they tend to have significantly lower choline levels than men A major brain imaging study confirmed that obesity directly causes brain shrinkage, white matter damage, and reduced cognitive performance — not just a correlation Simple lifestyle shifts like eating more choline-rich foods, cutting seed oils, moving daily, and prioritizing sleep can help repair and protect your brain long before problems show up
Avoidant restrictive food intake disorder (ARFID) is an eating disorder where people severely restrict food due to fear, sensory sensitivities, or low interest — not body image concerns — causing significant health and social problems Unlike normal picky eating, ARFID involves intense distress, extremely narrow food choices, nutritional deficiencies, weight loss, and serious disruption to daily life and social activities Prevalence ranges from 0.35% to 6.4% depending on region, primarily affecting children and teens, with average diagnosis at age 11 and higher male representation than other disorders Treatment approaches include parental control strategies, cognitive behavioral therapy, family-based treatment, food therapy, and sequential oral sensory methods to gradually reduce food-related fear and anxiety A specialized protocol combining psychology, hypnosis, and neuro-linguistic programming shows 90% success for adults and 65% for children, often achieved in single session
Fasting is one of the most powerful tools for fat loss, healing, and longevity, but it fails for many people because their metabolism is not prepared. In this episode, Ben Azadi explains why fasting feels miserable or unsustainable for most people and reveals the hidden metabolic mistakes that sabotage results before a fast even begins. You'll learn why being a sugar burner instead of a fat burner makes fasting feel like torture, how stress and poor sleep block fat burning, and why nighttime eating can completely ruin your fast the next day. Ben also breaks down how inflammation, toxins stored in fat cells, low protein intake, and an all-or-nothing approach to fasting lead to crashes, cravings, and failure. This episode covers: Why fasting fails when metabolic flexibility is low The role of insulin, cortisol, and inflammation in fasting success How stress, sleep, and nighttime eating impact fat burning Why toxins can make fasting feel worse instead of better How to properly prepare your body before fasting The 7 foundational steps to make fasting easier and effective How to know when your body is truly ready to fast If fasting has ever felt like failure or suffering, this episode explains why it was not your fault and how fixing the foundation can completely change your results. FREE GUIDE: Better Than Ozempic - https://bit.ly/3Y6YZtv
Beautiful soul, this episode is for any woman navigating perimenopause, menopause, or feeling confused by the emotional, mental, and physical shifts happening in her body. Julie is joined by Dr. Mindy Pelz for a powerful, grounded conversation that reframes hormonal change not as something breaking down, but as an initiation into wisdom, clarity, and deeper self-trust. Together, they explore why symptoms like brain fog, anxiety, irritability, sleep disruption, and emotional intensity are not failures, but messages from the body asking to be listened to differently. This episode gently reframes menopause as a spiritual and biological transition, intuition as a skill that strengthens with age, and metabolic health as a foundation for emotional balance. It is especially supportive for women feeling unseen by the medical system, overwhelmed by symptoms, or sensing that this season of life is calling them into a new level of leadership, truth, and alignment. Episode Chapters (4:06) Welcoming Dr. Mindy Pelz and her work in women's health (5:20) Why women are unprepared for perimenopause and menopause (9:14) Estrogen, progesterone, testosterone, and emotional shifts (16:12) Metabolic health, A1C, and symptom reduction (23:25) Fasting, food rhythms, and honoring the female body (30:16) Brain rewiring, intuition, and the wise woman phase (37:25) Hormone therapy, neurochemicals, and mental clarity (42:26) Relationships, boundaries, and identity changes (48:13) Anxiety, rumination, and nervous system support (58:49) Closing angel message: Heaven lives within you Work with Julie & Your Angels If you've been feeling the nudge I want to hear my angels clearly, I want to work with them every day, here's how to go deeper:
Butyrate, a short-chain fatty acid produced by gut bacteria that ferment dietary fiber, helps improve metabolic health by enhancing insulin function, regulating glucose levels and supporting healthy body composition Unlike most cells that use glucose, colonocytes (the epithelial cells that line your colon) prefer butyrate for energy, converting 70% to 80% through beta-oxidation to maintain gut barrier health Promoting butyrate production through fiber intake is beneficial, but only if your gut is healthy. If your gut is compromised, starting with dextrose water before transitioning to whole foods is recommended Lifestyle factors significantly impact butyrate production, with chronic stress, smoking, excessive drinking and antibiotic overuse reducing beneficial gut bacteria and SCFA production Excessive linoleic acid consumption, common in processed foods and vegetable oils, reduce beneficial gut bacteria, negatively affecting gut and metabolic health