Podcasts about metabolic

ReferencesCurr Opin Allergy Clin Immunol 2025, 25:444–454Guerra. DJ.2026. Unpublished Lectures.BiolOpen. 2019 Oct 15; 8(10): bio040311Lennon/McCartney. 1966. Rain. Beatleshttps://open.spotify.com/track/48TNLcToLs8DWkdj5vYdiW?si=375c43203c1c4ccdClapton/Bramlett, 1970. Let it Rainhttps://open.spotify.com/track/7DiaNCPgH5dJ1cJ925jTAA?si=b8bfac43cdef493cPage/Plant. 1973. The Rain Songhttps://open.spotify.com/track/3JLrri1xSCui3bzITDJbkk?si=6c47b7b4a0974806 Townsend, P. 1973. Love, Reign O'er Me. The Whohttps://open.spotify.com/track/4Mqs0h95KAeNiGp7u4udlt?si=56521c6a1b71425aLightfoot, G. 1975. Rainy Day Peoplehttps://open.spotify.com/track/1TZteKaf5z3P3i87jyB8jc?si=def4f81ab3ef4100

ReferencesNature Immunology 2018. volume 19, pages871–884 Guerra, DJ. 2026 Unpublished Lectures ChemBioChem,2018. .: 19, Issue: 15, Pages: 1657-1663, Morrison/Manzarek/Krieger/Densmore. 1971. Riders on the Storm. Doors.https://open.spotify.com/track/14XWXWv5FoCbFzLksawpEe?si=ee8db94467dd4d0a

What does real longevity actually look like? Is it the latest biohacking trend, or something much more foundational? In this episode, I sit down with Dr. Loren Marks, chiropractor and longevity-focused clinician, to discuss why the conversation around healthspan is rapidly becoming one of the most important topics in modern healthcare. Together, we explore how true longevity is less about chasing health fads and more about understanding and optimizing the body's fundamental physiological processes. Dr. Marks breaks down the difference between biohacking and sustainable longevity, emphasizing the importance of metabolic health, inflammation control, and personalized assessments. We discuss key biomarkers such as insulin and hsCRP, the role of muscle mass in aging well, and why balance training is one of the most overlooked strategies for preventing falls and maintaining independence later in life. If longevity is the healthcare conversation of the next decade, this episode offers a clear roadmap for practitioners and patients alike. From foundational metabolic markers to functional movement and personalized care, we explore how integrating modern science with clinical fundamentals can help people not just live longer, but live better.   Key takeaways: Longevity is rooted in physiological optimization rather than quick-fix biohacking techniques. Metabolic markers such as insulin, APOB, and HSCRP play crucial roles in determining health risks and should be part of regular health assessments. Muscle mass is pivotal for glucose disposal, fall prevention, and overall health, making strength training essential for longevity. Balance training can significantly reduce fall risks, a leading cause of serious injuries among older adults. More About Dr. Loren Marks: Dr. Loren Marks is a Manhattan-based Doctor of Chiropractic and board-certified Clinical Nutritionist with more than four decades of clinical experience guiding patients toward precision health, structural integrity, and long-term vitality. At his Midtown practice, Dr. Marks delivers executive-level health optimization through comprehensive metabolic analysis, advanced cardiovascular risk stratification, microbiome and gastrointestinal evaluation, hormone mapping, and precision structural care. His work integrates chiropractic medicine, functional nutrition, advanced blood chemistry interpretation, and non-invasive performance technologies into a cohesive, data-driven model of care. With a deep foundation in spinal biomechanics and neurophysiology, Dr. Marks brings extensive expertise in structural rehabilitation, chronic pain syndromes, neurologic function, and the relationship between biomechanical alignment and systemic health. His clinical approach recognizes that metabolic resilience, neurologic integrity, and structural stability are inseparable components of long-term performance and longevity. Dr. Marks is the author of a chapter in Arachnoiditis: The Evidence Revealed, edited by Antonio Aldrete, MD, and a contributing chapter author in Integrative Gastroenterology, edited by Gerard Mullin, MD, as part of the Andrew Weil integrative medicine series. His published work reflects a longstanding commitment to bridging structural medicine, gastrointestinal health, and systems-based clinical strategy. Known for synthesizing complex laboratory and clinical data into clear, strategic action plans, Dr. Marks focuses on identifying subtle patterns of dysfunction years before they manifest as overt disease. His philosophy is grounded in a core principle: sustainable longevity and peak performance are achieved not through isolated interventions, but through system-wide alignment — metabolic, neurologic, structural, and behavioral. Dr. Marks provides discreet, highly personalized care for individuals committed to measurable, evidence-informed health optimization. Licensed Doctor of Chiropractic in New York State. Board-Certified in Clinical Nutrition (DACBN). Website Instagram Connect with me! Website Instagram Facebook YouTube

High cholesterol is one of the most widely discussed—and established—risk factors in medicine. But reams of research now show that while it is key to cardiovascular risk, it is not the whole story.In this episode of A Whole New Level, editorial director Mike Haney sits down with Dr. Ronald Krauss, one of the world's leading lipid researchers and a pioneer in understanding how different forms of LDL—and the physiological factors around them—affect cardiovascular risk.Dr. Krauss explains why the basic link between cholesterol and heart disease is well established among experts—but also why the standard cholesterol panel often misses the deeper metabolic story. Drawing on decades of research, he walks through how lipoproteins, particle size, triglycerides, and metabolic health interact to determine whether cholesterol actually becomes dangerous.Along the way, the conversation explores why cardiovascular disease remains the leading killer despite statins and decades of research—and how factors like obesity, insulin resistance, and inflammation reshape the lipid landscape in ways that traditional tests may not capture.The result is a clearer framework for understanding cardiovascular risk: not just how much cholesterol is in the blood, but how it's being transported, how long those particles circulate, and what metabolic conditions are driving them.Sign Up to Get Your Free Ultimate Guide to Glucose: ⁠⁠⁠https://levels.link/wnl⁠⁠In this episode, we coverWhy the cholesterol–heart disease link isn't actually controversial among researchersCholesterol vs. lipoproteins: why the particles carrying cholesterol matter more than the number itselfSmall dense LDL: how triglyceride metabolism produces the most harmful particlesApoB and particle counts: why many researchers prefer measuring particles instead of cholesterol massLipoprotein(a): the genetically driven risk factor affecting up to a third of the populationMetabolic syndrome: the cluster of conditions that amplifies cardiovascular riskWhy carbohydrates and metabolic dysfunction can drive harmful lipid patternsThe saturated fat debate: why food context and metabolic health matter more than simple fat categories

Hey all you Vipers! Mr and Mrs Weedman are back with another round of great cannabis news, hot topics, headlines, research and reports. Before they get going, they get normal -  seshing on some Juicy Fruit flower from their friends @Midwest_Terps.  Mr Weedman shares a recent federally funded study finding most consumers are replacing medications with CBD and a new research report finding CBD useful when treating liver diseases. Mrs Weedman talks about the potential for cannabis as a legitimate medicine for menopause, she shares a research report on the munchies and how cannabis affects appetite, and she talks about the women shaping today's regulated market.   Support The Show: https://www.buzzsprout.com/283607/supportTWITTER: @weedman420podYouTube: Weedman420 ChroniclesEMAIL:  weedman420chronicles@gmail.comSHOP: www.eightdecades.comIG: @eightdecadesEMAIL: eightdecadesinfo@gmail.com#CannabisTruth #StomptheStigma #HomeGrow #FreethePlant #Stoners #rosin  #Potheads #Vipers #CannabisCultureEducation #CannabisResearch #Weed #Marijuana #LegalizeIt #CannabisNews #CBD #Terpenes #PodcastCannabis #eightdecades #CannabisLifestyle #HealthyLifestyle #NaturalMedicine #CannabisIndustry #PlantMedicine #News #WeedResearch #MedicalMarijuana #Infused #420Podcast #420Education #Health #WeedWellness #WorldNews #Gardening #budtender #420Culture #hemp #dabs #hash #joints #edibles #weed #gummies #tincture #vapes #pauliesayssmokesmartArticle Links:*  https://www.marijuanamoment.net/millions-of-americans-use-cbd-as-a* https://www.greenstate.com/health/cannabis-menopause-symptoms/?utm_source=flipboard&utm_content=topic/cannabidiol* https://www.foxnews.com/health/cannabis-compounds-could-reverse-disease-affecting-one-third-adults?utm_source=flipboard&utm_content=user%2FFoxNews* https://www.marijuanamoment.net/scientists-reveal-what-types-of-food-the-marijuana-munchies-make-you-crave-the-most/?utm_source=flipboard&utm_content=ChefJeff314%2Fmagazine%2FCannabis+Currently* https://www.greenstate.com/business/cannabis-leaders-speak-to-the-next-generation-of-women/?utm_source=flipboard&utm_content=GreenState/magazine/GreenState+News+%26+LifeCOPYRIGHT 2021 WeedMan420Chronicles©Suggestions? Questions? Chat with us here.Support the show

Obesity is not simply excess weight—it is a metabolic and inflammatory state that can reshape cancer biology. Adipose tissue alters hormones, insulin signaling, inflammatory cytokines, and immune responses, creating conditions that favor tumor development. Evidence now links obesity with cancers of the breast, colon, endometrium, pancreas, liver, kidney, and esophagus. Understanding these mechanisms opens the door to precision prevention strategies, from weight management to metabolic therapies. The message from translational science is clear: metabolism and malignancy are deeply intertwined. #CancerResearch #ObesityScience #TranslationalMedicine

ReferencesMBOC 2011. Volume 22, Issue 18 3456–3464Guerra, DJ. 2026. Unpublished LecturesDiscoveries (Craiova). 2014 Sep 23;2(3):e29J Cell Mol Med. 2015 May 28;19(7):1427–1440J Cell Mol Med. 2015 May 28;19(7):1427–1440Signal Transduction and Targeted Therapy2025. volume 10, Article number: 254Dylan, B. 1964 Mr. Tambourine Manhttps://open.spotify.com/track/3RkQ3UwOyPqpIiIvGVewuU?si=7127b25041cf4972 Zevon, W. 2003. Keep Me in Your Heart for a Whilehttps://open.spotify.com/track/1fRlDQzrpvWd4BlIzifUkJ?si=0a8e5251592e49eaMozart, WA. 1773. Symphony 25 in G Minor K.183https://music.youtube.com/playlist?list=OLAK5uy_nYdGMRH0VYkIzQZQhIlX3utzG2dlDWurk&si=g3zc1O-3naltl3I7

ReferencesGuerra, DJ 2026. Unpublished LecturesBiol Open. 2019 Oct 15; 8(10): bio040311.Small GTPases. 2012 Jul 1;3(3):139–153.Cell Mol Biol Lett. 2024 Aug 10;29:108Front Immunol. 2019 May 31;10:1225Brain Commun. 2021 Mar 5;3(2):fcab020Balin M. 1967. Coming Back to Me Jefferson Airplanehttps://open.spotify.com/track/0TBntp6t4oS6UXjxikO5n7?si=ccff17969d2c4680Kokkonen, J. 1972. Water Song Hot Tuna https://open.spotify.com/track/5Qe0nAjBVDecK7SfZE9YUm?si=4c8689cc0a2e4a1ePaige, J 1974 Bron yr Aur Zeppelinhttps://open.spotify.com/track/5rgWj8h7lzbSmwpp0wFkXD?si=d08d8d2b18bc40dc

In this biochemistry-made-simple episode, Dr. Scott Watier and Tommy Welling use the powerful "metabolic battery" analogy to explain why some people feel stuck despite doing everything right with their fasting and food choices. They break down how excess glucose creates a traffic jam in your mitochondria by overloading NADH and depleting NAD+, which promotes insulin resistance and blocks fat burning even when you're following your fasting schedule perfectly. The hosts reveal why reaching for NAD+ supplements misses the point—it's like adding more battery packs to a device you never unplug—and instead provide actionable strategies to restore natural battery cycling through consistent fasting windows, protein-based meals, post-meal movement, and protected sleep. They explain how continuous glucose monitors show you the real-time movie of your metabolic battery's charge-discharge cycle, not just the final score like A1C tests, helping you understand why certain food choices create the wired-and-tired, crashing-after-meals pattern that sabotages your fasting efforts and keeps you trapped in a cycle of cravings and inconsistent results. ⁠⁠⁠⁠⁠Take the NEW FASTING PERSONA QUIZ! - The Key to Unlocking Sustainable Weight Loss With Fasting!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Resources and Downloads: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠SIGN UP FOR THE DROP OF THE ULTIMATE GUIDE TO BLOOD SUGAR CONTROL⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠GRAB THE OPTIMAL RANGES FOR LAB WORK HERE! - NEW RESOURCE! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠FREE RESOURCE - DOWNLOAD THE NEW BLUEPRINT TO FASTING FOR FAT LOSS!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠SLEEP GUIDE DIRECT DOWNLOAD⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠DOWNLOAD THE FASTING TRANSFORMATION JOURNAL HERE!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Partner Links: Get your⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ FREE BOX OF LMNT⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ here!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Get ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠25% off a Keto-Mojo⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ blood glucose and ketone monitor (discount shown at checkout)! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Click here!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Our Community: Let's continue the conversation. Click the link below to JOIN the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Fasting For Life Community⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply! If you enjoy the podcast, please tap the stars below and consider leaving a short review on Apple Podcasts/iTunes. It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them! Article Links: https://www.youtube.com/watch?v=7gN0hEyCO_E

Register for a live Q&A with Dr. Tommy Wood on Wednesday, March 25th.Decreased glucose uptake in the brain is often considered a hallmark of Alzheimer's disease. But Dr. Tommy Wood asks whether part of that metabolic signature may reflect how little cognitive demand we place on the brain.He sits down with Dr. Dominic D'Agostino for a nuanced conversation on metabolic health and cognitive function.. Dr. Wood is a neuroscientist, neonatal brain injury researcher, and author of The Stimulated Mind.This episode follows the metabolic thread through every stage of brain health. Pre-diabetes and type 2 diabetes as predictors of cognitive decline. Neurovascular coupling as the reason heart disease risk factors double as brain disease risk factors. Lactate crossing the blood-brain barrier to drive BDNF production where it actually matters. Creatine as a brain energy distributor that most people still only associate with muscle. Dr. Wood lays out his Three S Model — Stimulus, Supply, Support — and makes the case that cognitive demand drives glucose uptake into the brain the same way muscular contraction drives it into skeletal muscle.Questions Answered in This Episode:Does the brain respond to energy demand the same way skeletal muscle does?What role does creatine play in brain energy distribution, and what do the clinical trials show?Can heavy resistance training produce the same brain-relevant lactate response as HIIT?How should exercise be dosed after a concussion or traumatic brain injury?Is cognitive decline in your 50s, 60s, and 70s actually inevitable, or is that a statistical artifact?Why are pre-diabetes and metabolic syndrome among the strongest predictors of dementia?The mechanistic throughline here is demand-driven metabolism. Dr. Wood makes the case that the same principles governing glucose uptake in skeletal muscle apply to the brain — and the conversation gets into what that means for how we interpret FDG-PET data, design lifestyle interventions, and think about neurodegeneration itself.Find more at DrTommyWood.comSpecial thanks to the sponsors of this episode:✅ Fatty15 – Get 15% off a 90-day Starter Kit with code METABOLICLINK here✅ Troscriptions – Get 10% off your first order with code METABOLICLINK here✅ Toups and Co – Get 15% off your first order with code METABOLIC here✅ ZocDoc - Find and instantly book a top-rated doctor hereIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

If you're over 40 and doing "everything right" — eating clean, lifting weights, prioritizing sleep — but your metabolism feels slower, hunger feels stronger, and fat loss feels harder… This episode explains why. In this deep-dive rabbit hole, Coach Debbie Potts uncovers the powerful (and often overlooked) connection between bile flow, mitochondrial efficiency, GLP-1 signaling, hormones, and midlife metabolism. Bile acids are not just digestive fluids. They are metabolic signaling molecules that regulate: • GLP-1 and PYY (satiety hormones) • Insulin sensitivity • Fat oxidation • Thyroid receptor expression • Estrogen clearance (the estrobolome) • Microbiome balance • Inflammatory tone • Toxin elimination You'll learn how midlife hormonal shifts — including declining estrogen and testosterone — affect mitochondrial ATP production, bile synthesis, and receptor signaling. When bile signaling weakens, GLP-1 drops, hunger rises, insulin resistance increases, fat oxidation declines, inflammation builds, and metabolism adapts downward. This isn't a willpower problem. It's a signaling problem. High performers often feel this shift first because chronic stress suppresses digestion, weakens vagal tone, reduces stomach acid, impairs gallbladder contraction, and disrupts bile release. In this episode, Debbie connects the dots and explains the midlife cascade: Hormone shift → Mitochondrial decline → Bile signaling weakens → GLP-1 drops → Insulin resistance rises → Fat oxidation slows → Inflammation increases → Thyroid sensitivity declines → Metabolic rate adapts downward. You'll also learn why GLP-1 medications are exploding in popularity — and why restoring upstream physiology may be the more sustainable path. Instead of pushing harder, we sequence smarter. When flow restores, metabolism follows.

On the next episode of Redefining Health, we'll be joined by Christopher Davis to dive into the fascinating topic of metabolic health—what it truly means and how practitioners can effectively discuss it with their patients. Metabolic health is deeply tied to mitochondrial function, the "powerhouses" of our cells that drive energy production. When mitochondrial health is compromised, it can lead to a range of issues, from poor energy levels to chronic diseases. Factors such as oxidative stress, poor diet, lack of exercise, and environmental toxins all play a role in mitochondrial dysfunction. In this episode, we'll explore: What metabolic health really means and why it's essential for overall well-being. How practitioners can simplify the concept for patients and emphasize the importance of lifestyle factors like diet, exercise, and stress management. The role of VO2 Max as a powerful yet underutilized tool for assessing cardiovascular and metabolic health. VO2 Max, which measures the body's ability to utilize oxygen during exercise, is one of the best indicators of mitochondrial and cardiovascular health. Despite its value, it's not used enough in clinical practice. We'll discuss why this metric matters and how it can be integrated into patient care to provide a more comprehensive picture of health.   Join us for this insightful conversation as we redefine what it means to achieve and maintain metabolic health.

ReferenceseLife. 2022 Nov 25;11:e83073Lipids Health Dis. 2025 Jul1;24:225Cell Reports 2021 Volume 35, Issue 5109076May 04.Guerra, DJ. 2026 Unpublished LecturesMcGuinn/Parsons/White et al. 1968 Sweetheart of the Rodeo. The Byrdshttps://music.youtube.com/playlist?list=OLAK5uy_kejb97oJ9VJCssjIxpz2YeHK9htTy-wz0&si=kkIqFi6NfkhHCpl9

Every year, the clock change brings more than just a few days of fatigue. This episode uncovers the profound physiological impact of Daylight Savings Time, particularly the spring shift, on your health. Moving beyond anecdotal complaints, we delve into the published research revealing population-scale circadian disruption and its downstream effects. This is your ultimate guide to understanding the hidden dangers of Daylight Savings and how to prepare yourself and your clients to navigate the clock change with minimal impact on your heart, brain, and metabolic health. Topics discussed:- Circadian disruption- Spring shift risks- Physiological mechanisms- Metabolic dysregulation- Proactive strategies- Coaching opportunities---------- ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠My Live Program for Coaches: The Functional Nutrition and Metabolism Specialization ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.metabolismschool.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠---------- [Free] Metabolism School 101: The Video Series⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://www.metabolismschool.com/metabolism-101⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠----------Subscribe to My Youtube Channel: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://youtube.com/@sammillerscience?si=s1jcR6Im4GDHbw_1⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠----------⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Grab a Copy of My New Book - Metabolism Made Simple⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠---------- Stay Connected: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram: @sammillerscience⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Youtube: SamMillerScience⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook: The Nutrition Coaching Collaborative Community⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TikTok: @sammillerscience⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠----------“This Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast and the show notes or the reliance on the information provided is to be done at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment and is for educational purposes only. Always consult your physician before beginning any exercise program and users should not disregard, or delay in obtaining, medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. By accessing this Podcast, the listener acknowledges that the entire contents and design of this Podcast, are the property of Oracle Athletic Science LLC, or used by Oracle Athletic Science LLC with permission, and are protected under U.S. and international copyright and trademark laws. Except as otherwise provided herein, users of this Podcast may save and use information contained in the Podcast only for personal or other non-commercial, educational purposes. No other use, including, without limitation, reproduction, retransmission or editing, of this Podcast may be made without the prior written permission of Oracle Athletic Science LLC, which may be requested by contacting the Oracle Athletic Science LLC by email at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠operations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@sammillerscience.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. By accessing this Podcast, the listener acknowledges that Oracle Athletic Science LLC makes no warranty, guarantee, or representation as to the accuracy or sufficiency of the information featured in this Podcast."

In this episode, fertility expert Gabriela Rosa reveals one of the biggest blind spots in modern fertility care: many couples are pushed toward treatments like IVF before receiving a true diagnosis. She breaks down how fertility clinics often operate, why infertility is frequently misunderstood, and how underlying issues such as thyroid dysfunction, insulin resistance, and PCOS can significantly impact reproductive outcomes. Gabriela shares powerful patient stories, including Renee's own experience, to illustrate how personalized investigation and root-cause medicine can dramatically shift fertility trajectories. She also explains why fertility is a “team sport,” outlining her strategic approach to improving egg quality, hormonal balance, and metabolic health while interpreting key tests like AMH and follicle development timelines. The conversation concludes with practical guidance on nutrition's role in fertility, her “Three Rocks” framework for treatment, and a thoughtful decision tree to help women determine when egg freezing may or may not be the right choice. Gabriela Rosa, DrPH (Candidate, Harvard), is a Harvard-awarded fertility specialist, founder of The Rosa Institute, and author of Fertility Breakthrough: Overcoming Infertility and Recurrent Miscarriage When Other Treatments Have Failed. She pioneered telehealth-based, integrative fertility care, making evidence-based solutions accessible worldwide.Gabriela also created and hosts The Fertility Challenge, a free online program that reaches tens of thousands globally each year. Her F.E.R.T.I.L.E. Method® has supported more than 204,000 people across 111 countries, with published research demonstrating a 78.8% live birth rate among patients in her signature program—even after years of infertility, recurrent miscarriage, and failed treatments.SHOW NOTES:0:39 Welcome to the show!2:43 About Gabriela Rosa3:35 Welcome her to the podcast!4:47 The biggest blindspot in fertility9:05 How fertility clinics operate10:56 What does infertility mean?11:52 Getting a proper diagnosis12:36 Patient story16:26 IVF industry goals18:48 Miscarriage & Thyroid21:19 Renee's story23:35 IUI incentives & results25:19 Who benefits from IVF?27:50 *APOLLO NEURO*29:50 *CALOCURB*31:00 Who gets turned away from her clinic35:39 Who she does work with37:30 Fertility is a team sport40:05 Her strategy for improving fertility43:16 Timeline of eggs & follicles45:45 AMH testing & optimal ranges51:14 PCOS & Insulin Resistance55:04 Infertility and all-cause mortality1:01:03 Research on correlation between nutrition & fertility1:05:38 The 3 Rocks1:11:09 Egg Freezing decision treeRESOURCES:Apollo Neuro - code: BIOHACKERBABES for $90 offCalocurb - code: RENEE10Website: fertilitybreakthrough.comIG: @dr.gabrielarosa, @fertilitybreakthroughFB: FertilitySpecialistGabrielaRosaX: gabrielarosaTikTok: @gabrielarosafertilityPodcast: Talk Sex with Gabriela RosaSupport this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands

Can you reverse fatty liver disease with a ketogenic diet?Fatty liver disease is now one of the fastest-growing liver conditions in the world, affecting roughly 30% of adults and an increasing number of children. And in many cases, it's driven by metabolic dysfunction and insulin resistance.In this conversation, Dr. Bret Scher speaks with Dr. Amy Goss (University of Alabama at Birmingham) and Dr. Karen Jerome-Zapadka (Trajectory Health Partners) about the growing epidemic of metabolic dysfunction–associated steatotic liver disease (MASLD) and why carbohydrate restriction and ketogenic nutrition may be powerful tools for addressing it.In this interview, you'll learn:What MASLD (formerly NAFLD) is and why it's becoming so commonHow insulin resistance and excess carbohydrates contribute to fatty liverNew research showing how carbohydrate restriction can reduce liver fatWhy ketogenic and low-carb diets may improve liver metabolism beyond weight lossThe clinical experience of reversing fatty liver through metabolic therapyWhy lifestyle approaches often receive less attention than medicationsDr. Amy Goss and her team at the University of Alabama at Birmingham are currently conducting a large NIH-funded clinical trial investigating how carbohydrate restriction affects liver fat and insulin sensitivity in adolescents with fatty liver disease.At the same time, Dr. Karen Jerome-Zapadka is applying these metabolic principles in clinical practice at Trajectory Health Partners, helping patients reverse steatotic liver disease through carbohydrate reduction and comprehensive metabolic care. Together, their research and real-world clinical experience are helping advance a deeper understanding of how targeting metabolic dysfunction may transform the way fatty liver disease is treated.Curious about the safety of ketogenic therapy? Visit our Is Keto Safe topic page to see all of our top content on the topic: https://www.metabolicmind.org/resources/topics/is-keto-safe/

A couple weeks ago, I talked about chronification and how it's just a fancy word that makes things feel permanent when they're not. Today we're tackling another buzzword: metabolic migraines. And here's the thing... people hear this term and think they've been diagnosed with a different TYPE of migraine. Like there are hormone migraines over here, stress migraines over there, and metabolic migraines in their own category. But that's not how this works. If you've been told you have "metabolic migraines" and you're treating that one piece in isolation... this episode is going to change the way you think about what's actually happening in your body. In this episode: What metabolic migraines actually means (in plain English) Why it's NOT a separate "type" of migraine — and why that matters How metabolic dysfunction is connected to your gut, hormones, nervous system, and liver (it's all one system) Why treating metabolism alone won't work if you're not addressing what caused it The real question nobody asks: What made your metabolism break down in the first place? How chronic systemic inflammation drives metabolic dysfunction — and why that's good news Why focusing on blood sugar and supplements alone keeps you stuck at 20% better The 3-phase approach that heals metabolism by addressing the whole inflammatory picture (not just one pathway) My challenge to you: stop chasing labels and start asking what's inflamed Resources mentioned: Free Guide: Toxic Migraine Triggers Book a Migraine Breakthrough® Assessment Call:  Connect with me: Website: https://pages.debbiewaidlcoach.com/ Instagram: https://www.instagram.com/debbiewaidl.coach/ Facebook Group: Women's Migraine Freedom™    Disclaimer: The Migraine Freedom™ Your Way Podcast and information provided by Debbie Waidl and guests in this podcast is presented solely to provide helpful information, education, and entertainment on the subjects discussed. The use of information or resources mentioned on or linked from this podcast is at the user's own risk and discretion. This podcast is not intended to diagnose or treat any medical condition. For diagnosis or treatment of any medical problem, consult your own physician. Debbie Waidl and In The Balance Health Coaching LLC are not responsible for any medical conditions or liable for any damages or negative consequences from any treatment, action, application, or preparation to any person reading or following the information presented on this podcast. References are provided for informational purposes only and do not constitute an endorsement of any websites or other sources.

If you're on Wegovy, Zepbound, Ozempic, or Mounjaro — and worried about what happens when you stop — this episode is for you. The fear of gaining it all back is real. But weight regain is not inevitable. It's manageable. And I'm going to show you how. "What happens when you stop your GLP-1?" This is one of the most common questions I get in my clinic every single week. It's time I answered it publicly — with science, not fear. In this episode, I break down exactly what happens in your body when you stop your GLP-1, why weight regain happens, and the five pillars you need to protect your results, whether you're stopping by choice or out of necessity. Listen now! Episode Highlights: The physiological reason hunger surges and metabolism slows when you stop GLP-1s  What the SURMOUNT-4 clinical trial tells us about weight regain after stopping Tirzepatide Who is at highest risk for regaining weight  The 5 pillars of weight maintenance: protein, resistance training, carb awareness, appetite retraining, and medication transition strategy Connect with Dr. Alicia Shelly: Website | drshellymd.com Facebook | www.facebook.com/drshellymd Instagram | @drshellymd Linked In | www.linkedin.com/in/drshellymd Twitter | @drshellymd About Dr. Alicia Shelly Dr. Alicia Shelly was raised in Atlanta, GA. She received her Doctorate of Medicine from Case Western Reserve University School of Medicine in Cleveland, OH.  Dr. Shelly has been practicing Primary Care and Obesity medicine since 2014.  In 2017, she became a Diplomat of the American Board of Obesity Medicine. She is the lead physician at the Wellstar Medical Center Douglasville. She started a weekly podcast & Youtube channel entitled Back on Track: Achieving Healthy Weight loss,  where she discusses how to get on track and stay on track with your weight loss journey. She has spoken for numerous local and national organizations, including the Obesity Medicine Association, and the Georgia Chapter of the American Society of Metabolic and Bariatric Surgeons. She has been featured on CNN, Fox 5 News, Bruce St. James Radio show, Upscale magazine, and Shape.com. She was named an honoree of the 2021 Atlanta Business Chronicle's 40 under 40 award. She also is a collaborating author for the, "Made for More: Physician Entrepreneurs who Live Life and Practice Medicine on their own terms''. Resources: FREE! Discover the 5 Reasons Your Weight-Loss Journey Has Gotten Derailed (And How To Get Back On Track!)

ReferencesGuerra. DJ 2026. Unpublished LecturesLipids Health Dis. 2025 Jul1;24:225Jagger/Richards. 1969 Paint it Blackhttps://open.spotify.com/track/63T7DJ1AFDD6Bn8VzG6JE8?si=7cb90ffb26b54512Beethoven LV. 1804 Symphony 3 in E Flat Major. Eroicahttps://music.youtube.com/watch?v=fhHcty9OM-0&si=ZWJt3uJUkjXY9ujt

ReferencesGuerra, DG. 2026. Unpublished LecturesLipids Health Dis. 2025 Jul 1;24:225Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7661–7666Leadon/Frey/Henley/Meiser/Blue/Souther/Norman. 1973 Desperado Eagleshttps://music.youtube.com/playlist?list=OLAK5uy_k3UBMdBe0k-PWX6y1VCLJZVJogoUaKEco&si=KAdQVnU-qVFn_r52

ReferencesiScience 2024. 27, 109267, March 15, Front. Immunol., 2018,03 December Sec. T Cell Biologyv9Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7661–7666Townsend, P 1973. Im One The Who Quadrophenia. https://music.youtube.com/watch?v=qvPVw0l5XpY&si=jHjslRqdHZH21KGHMozart, WA 1786. Piano Concerto in A Major. K 488.https://music.youtube.com/watch?v=V4S6UYv8-W4&si=AmbTM2OPzO10wJjx

He explains how sugar, especially fructose and fruit, fuels cancer—drawing on 40 years of data and research from Thomas Seyfried. #SugarAndCancer #MetabolicDisease #HealthTalks

ReferencesJ Biol Chem. 2011 Apr 8; 286(14): 11937–11950.Cardiovasc Diabetol.2020; 19: 33.J Cell Physiol. 2021 Apr;236(4):2333-2351Cytometry 2006. Part A 69 Issue 3Mar. Pages105-208Lennon/McCartney. 1964 Hard Day's Night. lphttps://music.youtube.com/playlist?list=OLAK5uy_kNANFuHzr_3bZH3S5aXxOT4X1ouKnjY4k&si=02aKQ86d5RTfyyY7CSNY, 1970. Deja Vu lp.https://music.youtube.com/playlist?list=OLAK5uy_neUnMuHswIr4wB5qPiV5iozF-550Cz3k8&si=neIOWnSei3lU7e07

Send a textMitochondria in human evolution, climate adaptation, maternal genetics, aging, and disease.TOPICS DISCUSSED:Endosymbiotic theory: Mitochondria arose from oxidative bacteria engulfed by archaea-like hosts, confirmed by phylogenetic analysis.Maternal mtDNA inheritance: Mitochondrial DNA is inherited from the mother, not the father. There are adaptive reasons for this.Haplogroups & adaptation: Tropical lineages tightly couple energy production for efficiency; northern ones uncouple to generate heat.Heteroplasmy & aging: Mixed mutant and normal mitochondria accumulate in cells, eroding energy in high-demand tissues like brain and heart.Bioenergetics in disease: Many common conditions, from Parkinson's to cancer, stem from mitochondrial-nuclear interactions rather than nuclear genes alone.Ketogenic diets: High-fat intake fuels mitochondrial beta-oxidation, which may compensate for brain energy deficits in epilepsy and bipolar disorder.Warburg effect: Cancer cells shift to glycolysis to prioritize biosynthetic building blocks over maximal ATP production.Modern mismatches: Global travel pairs ancestral mtDNA with mismatched diets and climates, raising risks for metabolic dysfunction.ABOUT THE GUEST: Douglas Wallace, PhD is a geneticist and evolutionary biologist who has studied mitochondria for over 50 years. He currently directs the Center for Mitochondrial and Epigenomic Medicine at Children's Hospital of Philadelphia and the University of Pennsylvania.RELATED EPISODE:M&M 260 | Energy Resistance Principle in Life, Healing & Disease | Martin Picard & Nirosha MuruganSupport the showHealth Products by M&M Partners: SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off. Lumen device: Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts

ReferencesAm J Physiol Cell Physiol. 2020 Dec 9;320(3):C415–C427Cell Physiol Biochem. 2015 Feb 11;35(4):1253–1275. Molecular Cancer 2017. 16(1)DOI: 10.1186/s12943-017-0699-3Guerra, DJ 2026. Unpublished LecturesMozart, WA. 1787. Don Giovanni Overture K.527https://open.spotify.com/track/7JINUFIVIptR7hlQYayU3h?si=5d92671383214c71

Guest host Dr. Scott Faulkner ( https://castlerockregenerativehealth.com) leads Health & Wellness Wednesday on Rush to Reason, joined by Jeremy Sova (biohacker and health optimization researcher), Regina Nabrit (mental health and behavioral health specialist), and later Josh Gardner (peptide expert). The hour opens with a sober reflection on current world tensions and a reminder to stay grounded in faith and perspective—but how do you stay informed without becoming overwhelmed? Regina Nabrit explores the growing mental health crisis tied to social media addiction, dopamine overload, and constant digital stimulation. Are smartphones quietly destroying sleep, relationships, and emotional resilience? The team introduces practical tools—including the “Four D's” strategy—to help listeners regain control of their attention and mental well-being. From there, the conversation pivots into cutting-edge biohacking and longevity science. Jeremy Sova breaks down the importance of biomarkers, vitamin D optimization, omega-3 levels, and targeted supplementation, arguing that modern food alone may no longer provide the nutrients our bodies need. Then the discussion dives even deeper into cellular aging, including the concept of “zombie cells” (senescent cells) that may drive inflammation, disease, and accelerated aging. Could emerging therapies—from natural senolytics to peptides and regenerative medicine—help the body repair itself? What simple steps today could dramatically change your long-term health? HOUR 2 Health & Wellness Wednesday on Rush to Reason, continues as the conversation dives deeper into peptides, cellular energy, and metabolic health, exploring why declining NAD levels may contribute to brain fog, fatigue, and aging. Could new sublingual peptide delivery technology dramatically improve absorption—bypassing digestion and delivering compounds directly into the bloodstream and even past the blood-brain barrier? Josh Gardner explains how peptides such as BPC-157, Thymosin Alpha-1, and GHK-Cu are used to support immune function, tissue repair, and inflammation control. Meanwhile, Jeremy Sova connects the dots between metabolic dysfunction, insulin resistance, and modern chronic disease, noting that widely known drugs like GLP-1 treatments (Ozempic-type medications) are themselves peptides. The panel emphasizes the importance of biomarker testing and personalized medicine, warning that many people chase quick fixes without understanding what's actually happening inside their bodies. Could a deeper look at hormones, metabolism, and mitochondrial health add years—maybe even decades—to your healthspan? The discussion builds toward emerging therapies and the possibility that modern regenerative medicine may rewrite the future of aging. HOUR 3 In hour 3 of Rush To Reason, the conversation explores the cutting edge of longevity science, starting with the battle against cellular senescence—“zombie cells”—and simple compounds that may help the body clear them out. Could nutrients like fisetin, quercetin, and omega-3s influence brain inflammation and even neurodegenerative disease pathways? Josh Gardner shares his personal journey into fasting and peptide therapy, explaining how peptides targeting mitochondria, recovery, and growth hormone may help restore cellular energy. The discussion then shifts to telomere length, the protective caps on chromosomes linked to aging. Are therapies like epithalon peptides and hyperbaric oxygen therapy capable of extending healthspan? Jeremy Sova reveals surprising insights from his own continuous glucose monitoring experiments, including which foods caused dramatic metabolic spikes—and which simple habits stabilized blood sugar. Finally, the team tackles stem cell exhaustion, regenerative medicine, and the future of healing. Could emerging therapies—from NAD+ delivery to immune-support peptides like Thymosin Alpha-1—transform how we approach aging, recovery, and disease prevention?

A patient with metabolic disease develops progressive shoulder pain with loss of motion, proximal thigh weakness, and has a history of low‑trauma fractures. The physical exam shows periarticular tenderness and visible muscle atrophy.  The patient also reports the muscular weakness is worsened at the end of each day. Which of the following conditions is MOST likely present? Find it all out in the podcast! Be prepared for the NPTE so that you can pass with flying colors! Check out www.ptfinalexam.com/podcast for more information and to stay up-to-date with our latest courses and projects. #Npte #PT #ptboards #crushtheNPTE #study #studygram #spt #ptstudent #ptlife #sptprobs #physicaltherapystudent #physicaltherapy #physio #physiotherapist #ptlife #ptstudentstudy

Reverse dieting has been a buzzword in fitness for years, promising a way to increase calories without gaining fat. But why do so many coaches and individuals still get it wrong? This episode dives deep into the 5 crucial mistakes that can derail your reverse diet, turning a promising strategy into a frustrating setback. Topics discussed: - Individual factors- Importance of adherence - Impact of gut issues on digestion and bloat- Metabolic adaptation- Nuance in approach for athletes vs. general population---------- ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠My Live Program for Coaches: The Functional Nutrition and Metabolism Specialization ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.metabolismschool.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠---------- [Free] Metabolism School 101: The Video Series⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://www.metabolismschool.com/metabolism-101⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠----------Subscribe to My Youtube Channel: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://youtube.com/@sammillerscience?si=s1jcR6Im4GDHbw_1⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠----------⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Grab a Copy of My New Book - Metabolism Made Simple⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠---------- Stay Connected: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram: @sammillerscience⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Youtube: SamMillerScience⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook: The Nutrition Coaching Collaborative Community⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TikTok: @sammillerscience⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠----------“This Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast and the show notes or the reliance on the information provided is to be done at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment and is for educational purposes only. Always consult your physician before beginning any exercise program and users should not disregard, or delay in obtaining, medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. By accessing this Podcast, the listener acknowledges that the entire contents and design of this Podcast, are the property of Oracle Athletic Science LLC, or used by Oracle Athletic Science LLC with permission, and are protected under U.S. and international copyright and trademark laws. Except as otherwise provided herein, users of this Podcast may save and use information contained in the Podcast only for personal or other non-commercial, educational purposes. No other use, including, without limitation, reproduction, retransmission or editing, of this Podcast may be made without the prior written permission of Oracle Athletic Science LLC, which may be requested by contacting the Oracle Athletic Science LLC by email at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠operations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@sammillerscience.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. By accessing this Podcast, the listener acknowledges that Oracle Athletic Science LLC makes no warranty, guarantee, or representation as to the accuracy or sufficiency of the information featured in this Podcast."

referencesCell Death & Disease 2026. 17, Article number: 71 Am J Physiol Cell Physiol. 2020 Dec 9;320(3):C415–C427Guerra, DJ.2026. Unpublished LecturesJagger/Richards. 1964. As Tears Go By. Marrianne Faithful https://open.spotify.com/track/2EYXCRp63iQdmeKHXN8Rrg?si=70ceced5d9304eb8Mozart , WA 1779. Sinfonia Concertante in E flat Major K.364https://music.youtube.com/watch?v=_0hTDZ0whpU&si=NNbjswoPokVPveuu

Get free access to our new Ketogenic Metabolic Therapy ebook here.Could changing your metabolism reduce alcohol cravings, ease psychiatric symptoms, and even make cancer immunotherapy more effective? The science is pointing to yes, and the mechanisms are fascinating.In this Journal Club episode, co-hosts Victoria Field, Dr. Dominic D'Agostino, and Dr. Angela Poff break down five peer-reviewed papers from their newly released Ketogenic Metabolic Therapy ebook (Volume 4). From a French preclinical study showing ketogenic diet enhances PD-L1 immunotherapy response in kidney cancer, to an NIH/UPenn trial using machine-learning-derived fMRI signatures to measure reduced alcohol cravings during ketosis, to Stanford's pilot trial demonstrating notable metabolic and psychiatric improvements in schizophrenia and bipolar disorder, this episode covers the cutting edge of metabolic therapy research.Questions Answered in This Episode:Why does the brain crave alcohol in people with alcohol use disorder, and how might ketones help? How might a ketogenic diet affect a tumor's response to immunotherapy?Can insulin resistance in the brain contribute to psychiatric symptom severity?How does the ketogenic diet compare to the Mediterranean diet for autoimmune inflammation?Does timing of ketogenic diet initiation matter for chronic pain relief?Is it realistic for people with serious mental illness to adhere to a ketogenic diet?Whether you're a clinician, researcher, or someone looking to understand the latest science, this episode reveals just how far-reaching ketogenic metabolic therapy has become, spanning oncology, psychiatry, addiction, autoimmune disease, chronic pain, and much more!In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

In this episode of Keeping Abreast, Dr. Jenn Simmons is joined by Jen Nolan and Sara Stratton of Remission Nutrition for a conversation that cuts through the noise around “healthy living” after a breast cancer diagnosis.Jen explains how nutrigenomics (genetic-based nutrition + lifestyle guidance) helps women understand what their body actually needs, from detox capacity to fat metabolism to exercise tolerance. Dr. Jenn shares her own example: years of high-intensity endurance workouts that she thought were helping until genetic testing revealed they were doing real harm.Sara shares her story of being diagnosed with stage 3C triple positive breast cancer at 37, and how she supported her body through chemotherapy and recovery using a metabolic approach, including fasting around treatment, strength training, mindfulness, and carefully chosen supplements. Together, they talk about how to make changes without overwhelm, avoid fear-based restriction and orthorexia, navigate resistance from conventional providers, and build a lifestyle that's sustainable long-term - with joy included.In This Episode, You'll Learn:What nutrigenomics can tell you about food, detox, sleep, stress, and exerciseSara's approach to supporting her body during chemo: fasting, movement, mindfulness, and recoveryWhat to know about supplements during chemotherapy including why antioxidants can be trickyWhy people get overwhelmed after diagnosis, and how to start with small, realistic stepsThe “crowding out” method: what to add first so healthy habits stickCommon non-negotiables that move the needle fast (Diet soda + processed snack foods)How to avoid orthorexia and stop turning food into fearHow to advocate for yourself when your oncologist dismisses integrative toolsEpisode Timeline: 01:06 Introducing Jen Nolan + Sara Stratton 04:10 Nutrigenomics and personalized healing 10:56 Sara's diagnosis at 37 + what life looked like before 13:55 Metabolic approach during treatment (fasting, keto, movement) 24:14 Fasting around chemo + how she trained through treatment 28:47 Supplements + what to avoid during chemotherapy 32:11 Fat metabolism genes + why keto doesn't work the same for everyone 35:59 How to start without overwhelm (3 changes at a time) 44:44 Treatment phase vs. long-term lifestyle (graduating from strictness) 49:55 Why conventional providers resist integrative support 51:43 What to do when your oncologist dismisses fasting/nutrition 54:34 Why breast cancer is usually not an emergency (and time matters) 58:48 Joy, purpose, and living while healingTo talk to a member of Dr. Jenn's team and learn more about working privately with Dr. Jenn visit: https://calendly.com/stephanie-1031/clarity-callTo get your copy of Dr. Jenn's book, The Smart Woman's Guide to Breast Cancer, visit: https://tinyurl.com/SmartWomansBreastCancerGuideTo purchase the auria breast cancer screening test go here https://auria.care/ and use the code DRJENN20 for 20% Off.Connect with Dr. Jenn:Website: https://www.jennsimmonsmd.com/Facebook: https://www.facebook.com/DrJennSimmonsInstagram: https://www.instagram.com/drjennsimmons/YouTube: https://www.youtube.com/@dr.jennsimmons

ReferencesGuerra, DJ. 2026. Unpublished LecturesScience Translational Medicine 2019: 17 Jul. Vol. 11, Issue 501, eaav7816Lennon/McCartney. 1969. Let it Be Beatleshttps://open.spotify.com/track/7iN1s7xHE4ifF5povM6A48?si=77799fa1a6ca494e

ReferencesGuerra, DJ. 2026 Unpublished LecturesCell.2022 Jun 16;185(14):2542–2558.e18. https://omim.org/entry/607358Experimental & Molecular Medicine2025 57:1881–1892Hunter/Garcia, 1968. Dark Star Grateful Dead Live/Dead LP https://open.spotify.com/track/07CwWCJetytT1cSnQOgRMU?si=de8e173488834efb

GLP-1 medications are either wildly overhyped or harshly criticized depending on the week—and one of the loudest concerns right now is that they “cause muscle loss.” In this episode, I'm digging into what the research actually shows about lean mass changes on GLP-1s, what's being misunderstood online, and what patients and clinicians can do to protect muscle while still benefiting from these powerful therapies. To help me unpack this, I'm joined by Dr. Michael Tsoukas, Associate Professor of Medicine in the Division of Endocrinology at the McGill University Health Centre, Co-Director of the Metabolic & Weight Optimization Clinic, and a clinician-scientist whose work focuses on GLP-1 pharmacotherapy and obesity treatment. He's trained at Tufts, McGill, and Harvard, and has authored over 50 peer-reviewed publications.We talk about where the muscle-loss concern came from, how GLP-1 weight loss compares to bariatric surgery and diet-only approaches, and whether lean mass loss always reflects true functional muscle loss. We also get practical, discussing resistance training and protein targets (it's more than you may think!).If you're on a GLP-1, considering one, or prescribing them—this is a science-based conversation that separates fear from facts.Guest: Dr. Michael TsoukasWebsite: mwoc.caWORK WITH MEJoin my Weight Loss Coaching Program for women, Best Weight https://www.sashahighmd.com/bestweightRecover Strong for Binge Eatinghttps://www.sashahighmd.com/bedO​​ntario-Wide Virtual Obesity Management Clinichttps://www.highmetabolicclinic.comTaking the first step toward weight loss can feel overwhelming — but you don't have to do it alone. I've created a curated list of my podcast episodes to gently guide you as you begin your journey. https://www.sashahighmd.com/podcast-guideFOLLOW SASHAInstagramhttps://www.instagram.com/sashahighmd/

Cheap food holds capitalism together. But to get it, we've had to cheapen almost everything on the planet: the work of women, nature and colonies. We've made strange new ecologies all over the world, and now we're living in the metabolic sh*tshow. How will the ruling class keep control? On this week's Do Your Own Research, […]

ReferencesImmun Ageing. 2020; 17: 2.Trends in Immunology. 2017. REVIEW| VOLUME 38,ISSUE 4, P287-297, APRIL 01, Int J Mol Sci. 2025 Apr 27;26(9):4147Experimental & Molecular Medicine 2019. volume 51, Article number: 80 Beethoven, LV 1811. Piano Concert V in E Flat Major OP 73.https://music.youtube.com/watch?v=q-hn8WH_-3U&si=TNpna_2DZLIoX2nM

What if your anxiety, brain fog, or mood swings aren't psychological flaws—but signs of a brain energy crisis? In this episode, we explore Metabolic Psychiatry, insulin resistance, mitochondrial health, and the emerging science behind brain energy metabolism. You'll learn how Metabolic Synchronization—aligning blood sugar, lean muscle mass, and mitochondrial function—may be the missing link to mental clarity, cognitive resilience, and long-term life control. If the brain is an energy system, then reclaiming your mental agency begins with metabolic repair. Let's make sense of it. #MetabolicPsychiatry #BrainEnergy #MentalHealth2026 #InsulinResistance #MitochondrialHealth Follow Dr. JC Doornick and the Makes Sense Academy:► Makes Sense Substack - https://drjcdoornick.substack.com ► Instagram: / drjcdoornick ► Substack: / drjcdoornick ►Facebook:  / makessensepodcast ►YouTube:  / drjcdoornick MAKES SENSE PODCAST Welcome to the Makes Sense with Dr. JC Doornick Podcast. This podcast explores topics that expand human consciousness and enhance performance. On the Makes Sense Podcast, we acknowledge that it's who you are that determines how well what you do works, and that perception is subjective and an acquired taste. When you change the way you look at things, the things you look at begin to change. Welcome to the uprising of the sleepwalking masses. Welcome to the Makes Sense with Dr. JC Doornick Podcast. SUBSCRIBE/RATE/REVIEW & SHARE our new podcast. FOLLOW Podcast: You will find a "Follow" button in the top right. This will enable the podcast software to alert you when a new episode launches each week. Apple: https://podcasts.apple.com/ca/podcast/makes-sense-with-dr-jc-doornick/id1730954168 Spotify: https://open.spotify.com/show/1WHfKWDDReMtrGFz4kkZs9?si=003780ca147c4aec Podcast Affiliates: Kwik Learning: Many people ask me where I get all these topics, which I've been covering for almost 15 years. I have learned to read nearly four times faster and retain information 10 times better with Kwik Learning. Learn how to learn and earn with Jim Kwik. Get his program at a special discount here: https://jimkwik.com/dragon OUR SPONSORS: Makes Sense Academy: A private mastermind and psychologically safe environment full of the Mindset and Action steps that will help you begin to thrive. The Makes Sense Academy. https://www.skool.com/makes-sense-academy/about The Sati Experience: A retreat designed for the married couple that truly loves one another, yet wants to take their love to that higher magical level. Relax, reestablish, and renew your love at the Sati Experience. https://www.satiexperience.com Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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This week I interviewed Reed Davis for the second time! Reed Davis is a Board Certified Holistic Health Practitioner(HHP) and Certified Nutritional Therapist (CNT), is an expert in functional lab testing and holistic lifestylemedicine. He is the Founder of Functional Diagnostic Nutrition (FDN) and the FDN Certification Course with over 4,000 graduates in 50 countries. We discussed how to avoid environmental toxins, the new food pyramid, Reed's top health principals and his one tip to get your body back to what it once was! Connect with Reed: https://www.functionaldiagnosticnutrition.com/“FDN Methodology in Action” case study series at https://www.fdntraining.com/eatclean26--------How to Take Simple Steps to Reclaim the Body, Energy, and Strength You Had 10-15 Years Ago Using My Stepladder System:https://www.stepladdersystem.com/FREE Nutrition Cheatsheets:https://brian-getleaneatclean.beehiiv.com/subscribeClick to book a FREE 15 minute consult with Brian:https://calendly.com/bdgryn/15min------------Interested in Upgrading your Mitochondria, Improving Energy and Sleep! Check out Troscriptions: https://bit.ly/4ik5kK5Use Discount Code for 10% OFF: EATCLEAN----Watch Get Lean Eat Clean podcast video episodes on YouTube!YouTube.com/@briangryn3680----B.rad Whey Protein Isolate Superfuel:The Best Protein on The Planet! Available in Two Delicious Flavors: Vanilla Bean and Cocoa BeanUse Coupon Code glec10off for 10% off your order!https://a.co/d/731gssV----My favorite health bars with clean ingredients!https://www.eatprima.com/BRIAN6816310% OFF with this link!

Show Notes HOST Melody Hartzler | | Book Appointment AROUND THE TABLE Kara Siedman | ResBiotic In Today's Episode In this episode of the Tables Talk Podcast, Dr. Melody Hartzler sits down with Kara Siedman, RD, CDCES, Director of Partnerships at ResBiotic, to examine how microbiome-driven physiology intersects with hormonal transitions during perimenopause and menopause. As estrogen and progesterone fluctuate and decline, women experience predictable shifts in metabolic regulation, immune signaling, and inflammatory burden. Increasing evidence suggests these changes are tightly linked to alterations in gut microbial diversity, intestinal barrier integrity, and microbial metabolite production. This conversation explores the gut–hormone axis through a mechanistic lens, highlighting how microbiome dysfunction may amplify symptoms such as blood sugar instability, weight gain, estrogen dominance, gastrointestinal distress, and genitourinary changes. Kara draws on clinical experience and emerging research to clarify why many hormonally driven symptoms occur in the absence of overt disease on conventional testing. The episode emphasizes perimenopause as a critical intervention window—one in which targeted dietary, lifestyle, and microbiome-supportive strategies may meaningfully influence long-term cardiometabolic and immune health. Key Takeaways Hormonal decline during perimenopause is closely linked to reduced microbiome diversity and resilience Estrogen loss impacts intestinal barrier function, inflammation, and metabolic regulation The estrobolome plays a central role in estrogen metabolism and symptom expression Microbiome-targeted interventions may reduce cardiometabolic risk during menopause Diet, fiber diversity, and precision biotics are foundational tools for supporting this transition Episode Highlights Hormonal Transitions & the Gut–Hormone Axis Estrogen and progesterone fluctuations in perimenopause Bidirectional signaling between endocrine function and the microbiome Declining microbial diversity and reduced short-chain fatty acid production Inflammation, Metabolism, and Insulin Resistance Metabolic endotoxemia and LPS-driven inflammation Microbiome contributions to blood sugar dysregulation and weight gain Links between dysbiosis, immune activation, and chronic disease risk The Estrobolome & Estrogen Metabolism Beta-glucuronidase activity and estrogen deconjugation Microbial reactivation of estrogen and clinical implications Estrogen dominance, elimination pathways, and gut health Vaginal Microbiome & Genitourinary Health Estrogen-dependent Lactobacillus depletion Increased risk of UTIs and yeast infections Gut–vaginal microbiome crosstalk and clinical considerations Clinical Interventions to Support Microbiome Resilience Mediterranean-style dietary patterns and plant diversity Fiber intake, resistant starch, prebiotics, probiotics, and postbiotics Stress, sleep disruption, medications, and microbiome vulnerability Precision supplementation during the menopausal transition

Best Of 2GG: Brooke at Metabolic (use your words wisely) by Two Girls and a Guy

ReferencesSCIENTIFIC REPORTS 2016 | 6:34594 | DOI:10.1038/srep34594 Seminars in Immunology 2025. V. 78,Jun, 101954Front Immunol. 2025 Jan 8:15:1515715Telemann, GP. 1735. Sinfonia Spirituosa TWV 40&50https://open.spotify.com/album/2nJX3LIjdAbNIGR3qbQaBI?si=VF-7aHcBS_qOkEsl34LdKQ

In this powerful episode, we sit down with Dr. Joe Zundell — aka “Cancer Daddy” — for a wide-ranging conversation on cancer science, early detection, and what's actually moving the field forward. We cover: • Multi-cancer early detection (MCED) testing and the promise of liquid biopsies • Accuracy, limitations, and clinical decision-making • Metabolic vulnerabilities in cancer (Warburg effect, glutamine dependence) • Epigenetics and tumor biology • Immunotherapy, targeted therapies, and radiopharmaceuticals • Translational research and the bench-to-bedside gap • Drug resistance and evolutionary pressure in cancer treatment • Personalized risk reduction and prevention strategies We also get very personal in this episode — discussing loss, integrity in academia, career pivots, and what truly drives Dr. Zundell's mission in cancer research. This is an honest, science-first, and deeply human conversation about cancer, prevention, innovation, and responsibility in modern medicine. Coach Vinny Email: vinny@balancedbodies.io Instagram: vinnyrusso_balancedbodies Facebook: Vinny Russo Dr. Eryn Email: dr.eryn@balancedbodies.io Instagram: dr.eryn_balancedbodies Facebook: Eryn Stansfield Dr. Joe Zundell Email: drjoezundell@gmail.com Instagram: dr.joezundell LEGION 20% OFF CODE Go to https://legionathletics.com/ and use the code RUSSO for 20% off your order!

Why does losing weight feel so much harder after 40? If you found it easy to lose weight and build muscle in your 30s, but now those same strategies barely make an impact, you're not imagining things. Your body is following a new set of rules. In this episode, we break down what happens to your hormones, your metabolism, and your muscle mass as you age, and, more importantly, what you can do about it. We explore everything from GLP-1 medications and peptide therapies to creatine, protein targets, and why resistance training is non-negotiable for maintaining weight loss. Whether you're just starting your weight loss journey or you've hit a frustrating plateau, this episode will help you understand what's happening in your body and what to do next. How to Maintain Muscle Mass While Losing Weight Do resistance training 2–3 times per week Eat about 100 grams of protein per day  Take 3–5 grams of creatine daily Ensure you are properly hydrated- aim for 100 ounces per day Use peptides  Consider targeted therapies Track your body composition instead of using the scale Bio: Stephanie Gray Stephanie Gray, DNP, MS, ARNP, AGNP-C, ABAAHP, FAARFM, is a functional medicine provider who helps men and women build sustainable, optimal health and longevity.  A nurse practitioner since 2009, Dr. Gray completed her doctorate focusing on estrogen metabolism from the University of Iowa in 2011 and holds a Master's in Metabolic Nutritional Medicine from the University of South Florida's Medical School. Dr. Gray is one of the Midwest's most credentialed female healthcare providers. She completed an Advanced Fellowship in Anti-Aging, Regenerative, and Functional Medicine in 2013 and became Iowa's first BioTe certified provider—now the state's only platinum provider with over 10,000 pellet placements. She is also certified as a SIBO doctor-approved practitioner, mold-literate provider, and ReCODE 2.0 practitioner for cognitive decline prevention. An Amazon best-selling author, Dr. Gray wrote Your Longevity Blueprint and Your Fertility Blueprint, and hosts the Your Longevity Blueprint podcast. She co-founded Your Longevity Blueprint Nutraceuticals with her husband, Eric. After her own ten-year fertility journey, she now specializes in helping couples optimize reproductive health through functional medicine. Having lost her grandmother to vascular dementia, she is personally committed to helping families avoid cognitive decline. Dr. Gray founded the Integrative Health and Hormone Clinic in Hiawatha, Iowa. In this episode: Why your weight loss strategy will need to change in your forties Why optimizing your hormones should be foundational to your weight loss strategy How resistance training helps to preserve your muscle mass when you're taking GLP-1s The benefits of creatine and peptides for women over 40 How the Emsculpt Neo can help with fat reduction The value of tracking your protein intake Why proper hydration is crucial for your muscles, metabolism, and regulating stress Links and Resources: Guest Social Media Links: @stephaniegraydnp Relative Links for This Show:  ⁠⁠⁠⁠⁠⁠Use Code FIBER to get 10% off GLP-1 Fiber⁠ ⁠⁠⁠⁠⁠Use code CREATINE to get 10% off Creatine Use code Drgray20 to get 20% off ⁠Perfect Aminos Follow Your Longevity Blueprint  On Instagram| Facebook| Twitter| YouTube | LinkedIn Get your copy of the Your Longevity Blueprint book and claim your bonuses here Find Dr. Stephanie Gray and Your Longevity Blueprint online   Follow Dr. Stephanie Gray  On Facebook| Instagram| Youtube | Twitter | LinkedIn Integrative Health and Hormone Clinic Podcast production by Team Podcast

In this episode of The Health Fix Podcast, Jay Campbell, best known for being the testosterone replacement therapy guru shares his two-decade plus journey into the world of peptides and hormone replacement therapy and how these compounds have transformed not just physique and fat loss, but metabolic health and longevity.  This conversation goes far beyond weight loss headlines and dives into the mental benefit side of health optimization. **We get real in this episode and there's some swear words so if you're listening with kiddos around listen with caution** What You'll Learn In This Episode: Why GLP peptides are reshaping obesity treatment The power of microdosing peptides, especially GLP-1's, for sustainable results Why education is the missing link for both clinicians and patients Injectable vs oral peptides — what actually works The role of lifestyle optimization alongside peptide therapy How misinformation (and AI amplification) is distorting public perception The humanitarian mission to make peptide therapies more accessible Peptides Are a Tool — Not a Shortcut Jay emphasizes that GLP peptides can dramatically improve metabolic health but without lifestyle changes, long-term success is limited. For those who want to stay active and adventure-ready, peptides may: Improve insulin sensitivity Reduce inflammation Support fat loss Enhance recovery But they are meant to amplify effort, not replace it.   Microdosing Changes the Game One of the most powerful strategies discussed is microdosing. Rather than high-dose protocols aimed purely at appetite suppression, strategic lower dosing can: Preserve muscle mass Reduce side effects Improve metabolic flexibility Support long-term sustainability This is particularly important for athletic or active adults who don't want to lose performance while improving body composition.   Injectable > Oral Jay explains why injectable peptides remain the gold standard due to bioavailability and effectiveness. Understanding delivery method matters especially for those investing in advanced health strategies.   The Future of Obesity Treatment We're entering an era where next-generation GLP and triple-agonist peptides are transforming how we address: Insulin resistance Chronic inflammation Fat loss resistance Metabolic disease But access, education, and responsible use are critical and why Jay and I do podcasts like this!   Health Optimization as a Spiritual Practice One of the most compelling parts of the conversation: When you optimize your biology, you elevate your capacity; physically, mentally, and spiritually. Health isn't vanity. It's vitality. It's freedom. It's staying in the game.   Resources From The Show: Jay's Website - https://jaycampbell.com/ Jay's Peptide Company - https://biolongevitylabs.com/ Jay's New Book - Metabolic Awakening with GLP-1 Peptides Dr. J's March 18th, 2026 Workshop: 5:30p PST/7:30p CST (register to get the replay if you can't make it live) - The Art of Staying Your Sport or Hobby and Being Adventure Ready at Any Age    

In this episode, I talk with Dr. Tommy Wood about how to protect and strengthen brain health across the lifespan—how overstimulation, chronic stress, and not giving your brain time to rest and recover undermines focus and productivity, and why restructuring your workday, prioritizing sleep, and building in real cognitive breaks can help you think more clearly and perform better. We discuss how the balance of stimulus, supply, and support shifts as we age, why retirement and prolonged illness can accelerate cognitive decline without ongoing challenge, and how physical activity, deep work, and continued learning help maintain function and even build “crystallized intelligence”—wisdom—later in life. We also get into genetic risk and why it’s largely a probability game where lifestyle can stack the deck in your favor; the powerful role of social connection and helping others in reducing dementia risk; how to use digital tools for real connection instead of passive consumption; and the cognitive effects of substances like nicotine, alcohol, cannabis, and stimulants. Dr. Tommy shares practical strategies—from structuring your day around focused work and restorative breaks to picking hobbies that challenge your brain—as well as simple ways to maintain cognitive function, extend the time you stay sharp, and lower the likelihood of decline over your life. TIMESTAMPS: Tommy Wood's new book explains the environmental impact on your brain health. [01:07] In adults over 40, dementia is the number one health concern. [07:21] Why haven't we done a better job of understanding the brain's neurological disease? [13:28] Studies have shown that an older adult learning a new language or musical instrument, experiences significant changes in the structure of the brain. [20:45] Failure is the primary driver of neuroplasticity. [21:35] If you do one of two activities such as attending lectures, writing, classes, volunteering, sports and such, you are best protected from dementia. [ 26:00] What are the three S's that are the key to long-term brain health and disease prevention? [29:08] Metabolic disease like high blood pressure is a significant risk factor for dementia. [35:13] People who are stressed usually don't give their brain time to recover. [36:03] Some people do have genetic influence and possibly have a higher risk that they can learn to work with. [38:33] It's estimated that 45 to 70 ish percent of dementias are preventable. [39:53] We can eliminate this accelerated decline that we are seeing around us by hitting the checkpoints like move, nourish, stimulate, connect and adapt. [47:06] The social connection is terribly important. [47:43] The areas of the brain that are most susceptible to decreases in function as we age, are the areas of the brain that are negatively impacted by being socially isolated. [51:27] What is the impact of the digital world that surrounds us? What about smoking and alcohol? [52:26] Marijuana use definitely has an effect on brain. [01:02:46] If someone only has a small amount of time to learn these things, what would be the tips you would give them? [01:07:34] LINKS: Brad Kearns.com BradNutrition.com - 20% OFF Your First Order! B.rad Superdrink – Hydrates 28% Faster than Water—Creatine-Charged Hydration for Next-Level Power, Focus, and Recovery B.rad Whey Protein Superfuel - The Best Protein on The Planet! Brad’s Shopping Page BornToWalkBook.com B.rad Podcast – All Episodes Peluva Five-Toe Minimalist Shoes Dr. Tommy Wood Instagram @drtommywood The Stimulated Mind: Future-proof your Brain Podcast with Wood: Metabolic Efficiency Podcast with Wood: Sensible Healthy Living Podcast with Wood: Beauty of Not Always Optimizing Nourish Balance Thrive Dr.TommyWood.com We appreciate all feedback, and questions for Q&A shows, emailed to podcast@bradventures.com. If you have a moment, please share an episode you like with a quick text message, or leave a review on your podcast app. Thank you! Check out each of these companies because they are absolutely awesome or they wouldn’t occupy this revered space. Seriously, I won’t promote anything that I don't absolutely love and use in daily life: B.rad Nutrition: Premium quality, all-natural supplements for peak performance, recovery, and longevity; including the world's highest quality whey protein! Get 20% OFF your first order! Peluva: Comfortable, functional, stylish five-toe minimalist shoe to reawaken optimal foot function. Use code BRADPODCAST for 15% off! Get Stride: Advanced DNA, methylation profile, microbiome & blood at-home testing. Hit your stride the right way, with cutting-edge technology and customized programming. Save 10% with the code BRAD. Online educational courses: Numerous great offerings for an immersive home-study educational experience Primal Fitness Expert Certification: The most comprehensive online course on all aspects of traditional fitness programming and a total immersion fitness lifestyle. Save 25% on tuition with code BRAD! See omnystudio.com/listener for privacy information.

Dr. Mark Tarnopolsky's VO2 max was once 87.6 ml/kg/min — an elite-level mark few humans have reached. He's competed at three world championships in three different sports. He's also had three cardiac ablation surgeries, bled from his bowels after races, and watched his vision tunnel to a speck crossing a finish line. His story is a master class in where the line falls between peak performance and self-destruction.Now 63, Tarnopolsky is a neurologist, neuromuscular disease specialist, and supplement formulator who has channeled decades of elite athletic experience and hundreds of published studies into the idea that keeping metabolic throughput high is what protects us as we age.In this conversation with Dom D'Agostino, he shares practical strategies anyone can apply: why resistance training three times per week is non-negotiable after 50, why post-exercise nutrient timing improved performance in a simulated training camp with identical calories, why he says creatine belongs in nearly everyone's regimen, and why he personally takes his mitochondrial supplement stack situationally after hard efforts rather than daily.Questions Answered in This Episode:What is the only intervention proven to extend human lifespan — and by how much?At what point does endurance exercise become pro-aging — and what are the warning signs?What simple nutrient timing strategy improved performance with zero extra calories?How did a bodybuilder bar conversation lead to a published discovery about growth hormone and collagen?What muscle and bone costs of Ozempic aren't getting enough attention?Why did elite endurance athletes need nearly as much dietary protein as bodybuilders — and why were bodybuilders massively overconsuming?This conversation reframes the longevity debate around what's actually been proven in human clinical trials — not Petri dishes, not animal models, and not social media influencers.Special thanks to the sponsors of this episode:✅ Troscriptions – Get 10% off your first order with code METABOLICLINK here.✅ Toups and Co – Get 15% off your first order with code METABOLIC here.✅ iRestore – Get a huge discount on the Elite and the Illumina bundle here. ✅ MudWtr – Get up to 43% off + free shipping and a free rechargeable frother with code METABOLICLINK here.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Dr. Frank Dumont is Executive Medical Director at Virta Health, where he leads medical strategy to advance safe, scalable metabolic care. A longtime internal medicine physician at Estes Park Medical Center, he previously directed its Wellness Service Line. A Fellow of the American College of Physicians, Dr. Dumont has also served in leadership roles with the Colorado Medical Society and the American Medical Association. In this episode, Drs. Brian and Frank talk about… (00:00) Intro (04:03) How Dr. Frank's personal health issues and professional experiences as a doctor led him to adopt a metabolic health approach to healing himself and his patients (10:41) Exercise, nutrition, and de-prescribing  (14:22) Fat adaptation and fasting (24:09) Virta's peer-reviewed publications and long-term data (30:09) The positive cascading effect on holistic health of metabolic lifestyle interventions (36:25) Social support and mental health (44:41) Dr. Frank's experience leaving a standard medical practice and becoming a metabolic health practitioner (52:22) Moral injury and physician burnout in the standard medical care system (54:05) Employe wellness and metabolic health care (01:01:01) Outro/plugs For more information, please see the links below. Thank you for listening! Links: Please consider supporting us on Patreon: https://www.lowcarbmd.com/   Dr. Frank Dumont: Virta Health: https://www.virtahealth.com/ X: https://x.com/FrankDumont Linkedin: https://www.linkedin.com/in/frank-d-dumont-46aa00b7/ Dr. Brian Lenzkes:  Website: https://arizonametabolichealth.com/ Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author Dr. Tro Kalayjian:  Website: https://toward.health Twitter: https://twitter.com/DoctorTro IG: https://www.instagram.com/doctortro/ Toward Health App Join a growing community of individuals who are improving their metabolic health; together.  Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.  Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888  Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US Learn more: https://toward.health/community/

Fat loss stalled? Low energy? It might not be calories — it could be fatty liver. In this episode, Ben explains how fatty liver silently slows metabolism long before symptoms appear, and why it is one of the most overlooked reasons for stubborn weight gain. You'll learn: • How liquid sugar and constant snacking overload the liver• Why insulin is the real fat-storage hormone• The power of a simple 12–16 hour fasting window• How walking after meals can blunt insulin spikes by over 30 percent• Why sleep is essential for restoring liver insulin sensitivity• The truth about fruit, alcohol, and dietary fat• Why coffee can either heal or harm your liver depending on quality Ben also breaks down how to reverse fatty liver naturally with a simple 3-step protocol: remove the overload, restore insulin signaling, and support detox. Plus, he shares a free egg-based protocol designed to help you lose the last 10 pounds while improving liver health. If your metabolism feels stuck, this episode will help you understand why — and what to do about it. Share this with someone who needs it and remember to practice Vitamin G: gratitude. New customers get 20% off with code BENAZADI at https://bit.ly/4rV6vEE  FREE GUIDE: How To Lose 1 Pound Of Fat Per Day HERE - https://bit.ly/4j45Yxa