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NEW! Support your strength and muscle goals with PUORI Creatine+ — a clean, effective creatine monohydrate supplement enhanced with taurine. Get 20% off at puori.com/VANESSA In this masterclass episode, Vanessa sits down with Dr. David Church, one of the most exciting young researchers in protein metabolism and a mentee of Dr. Arny Ferrando and Dr. Robert Wolfe. Together, they break down the latest science on protein timing, distribution, and supplementation — and how to apply it to achieve fat loss, preserve muscle, and enhance cognition. You'll learn: • How stable isotope tracer studies work and what they reveal about muscle protein synthesis (MPS). • The minimum protein per meal needed to trigger muscle growth and repair — and whether you can hit it with two meals a day. • The truth about intermittent fasting and muscle preservation — what happens to MPS in 2-meal and 1-meal-a-day patterns. • Why older adults and women over 40 face anabolic resistance and how EAAs (essential amino acids) can help overcome it. • What happens when you double your protein intake from 0.8 g/kg to 1.6 g/kg — and why distribution may matter less than total intake. • The surprising power of small doses of EAAs in muscle maintenance and cognitive support. • Why creatine is foundational for women, including new research showing benefits for brain health and sleep deprivation. • How to optimize body recomposition — burning fat while protecting lean mass — even during calorie restriction. • The difference between supplemental vs. replacement nutrition, and why EAAs work for older adults with low appetite. • The synergy of protein + resistance training + sleep + activity in driving sustainable fat loss. OneSkin is powered by the breakthrough peptide OS-01, the first ingredient proven to reduce skin's biological age. I use the OS-01 Face and Eye formulas daily—they've transformed my skin's smoothness, firmness, and glow. Visit oneskin.co/VANESSA and use code VANESSA for 15% off your first purchase Dr. Church also shares his own daily stack — including why he takes 20 g of creatine per day and combines it with EAAs for energy, cognition, and recovery — plus his favorite high-protein meals for busy days. If you've ever wondered how to burn fat efficiently while protecting every gram of muscle, this episode is packed with evidence-based takeaways you can implement right away. Mentioned in this Episode: • Puori Creatine + – clean, third-party-tested creatine monohydrate with taurine • Essential amino acids for older adults and women facing anabolic resistance • Stable isotope tracer studies — how we truly measure MPS • Protein targets: 1.6–2.4 g/kg depending on activity and energy restriction • Pre-sleep protein and its impact on overnight MPS and metabolic rate Get delicious high protein meal recipes! Connect with Vanessa on Instagram @ketogenicgirl Free High-Protein Keto Guide Get 20% off on the Tone LUX Crystal Red Light Therapy Mask or the Tone Device breath ketone analyzer at https://ketogenicgirl.com with the code VANESSA Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.
Send us a textDuncan Smart is no ordinary health voice.An international endurance athlete and the force behind his recent books CARNIVORE: The Manual: A Real-World Guide to Meat-Based Living. For Carnivore, Keto and Low-Carb Warriors and Blood & Bone: The Vampire's Guide to Carnivore Living, he wields metabolic science like a knife, carving through nutritional lies with ancestral fire.Known to readers as The Carnivore Vampire, Duncan fuses Slavic folklore, Mongol steppe wisdom, and Arctic survival rituals into a manifesto for the metabolically betrayed. His work is a rebellion against sickness, sedation, and the modern feedlot of dogma.He once walked the tamed path: teacher; vegetarian; cog in the machine - until his body screamed for the truth. His return to flesh, fire, and fasting sparked a visceral transformation: gut sealed, mind cleared, mission forged. Duncan dissects dogma with academic precision from his base in North Yorkshire's wild moors, where he trains, writes, and helps others to rewild their biology. Through the concepts of meat as sacred fuel, movement as ancestral ritual, and metabolic fire as birthright.Find Duncan at-IG- @duncsmartFB- @Duncan SmartBlood & Bone: The Vampire's Guide to Carnivore LivingCARNIVORE: The Manual: A Real-World Guide to Meat-Based Living. For Carnivore, Keto and Low-Carb WarriorsFind Boundless Body at- myboundlessbody.com Book a session with us here!
Beat BLOAT & unlock better protein absorption and digestion with MassZymes by BiOptimizers. NOW GET 15% off your order with the code VANESSA at bioptimizers.com/vanessa What separates people who keep fat off from those who regain it? In this episode, Vanessa Spina breaks down the latest research on long-term fat loss maintenance — including insights from one of the world's most respected obesity and metabolism researchers, Dr. James Hill. You'll learn the proven strategies that help preserve lean muscle, protect metabolism, and create sustainable fat loss — all backed by decades of science. Vanessa unpacks Dr. Hill's three-bucket model for lasting success, showing how to combine nutrition, activity, and mindset into a lifelong blueprint for body recomposition and metabolic health. Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa In this episode, you'll discover: • Why losing fat and keeping it off require two completely different skill sets • The research-backed protein and training strategies that preserve lean muscle • How small daily changes — like 100 fewer calories or 2,000 more steps — compound over time • Why exercise “fixes” your metabolism and helps you stay lean for life • The concept of your appetite sweet spot — and how to find it • How to shift from a “victim” to “voyager” mindset and make maintenance effortless • Dr. Hill's insights on GLP-1 medications and how to transition off without regaining weight If you've ever lost weight and struggled to maintain it, this episode will show you the science of what truly works — and how to protect your lean mass, metabolism, and confidence for the long term. Get my free NEW high-protein keto guide: The Keto Reset eBook Learn more about the TONE LUX Crystal red light therapy mask and the accessory the TONE LUX CONTOUR for the neck and décolleté and get 20% OFF with the code VANESSA Free high-protein keto guide: The Keto Reset eBook
NEW! Support your strength and muscle goals with PUORI Creatine+ — a clean, effective creatine monohydrate supplement enhanced with taurine. Get 20% off at puori.com/VANESSA In today's episode, Vanessa sits down with one of the most influential figures in obesity and metabolism research — Dr. James Hill, Professor of Nutrition Sciences at the University of Alabama at Birmingham and co-founder of the National Weight Control Registry. Dr. Hill has spent over four decades studying how people successfully lose weight, maintain it long-term, and preserve their lean mass and metabolic health. Dr. Hill has led landmark clinical trials such as the Diabetes Prevention Program, Look AHEAD, and the Beef WISE Study on high-protein diets. His decades of work reveal why weight loss is only the beginning — and why the real secret to success lies in learning the completely different skill set of maintenance. OneSkin is powered by the breakthrough peptide OS-01, the first ingredient proven to reduce skin's biological age. I use the OS-01 Face and Eye formulas daily—they've transformed my skin's smoothness, firmness, and glow. Visit oneskin.co/VANESSA and use code VANESSA for 15% off your first purchase In this conversation, you'll hear: The protein “lever” Dr. Hill uses to curb appetite and protect muscle during a cut—plus why the source may matter less than you think Three habits most long-term maintainers share (and one that surprised even him) The moment your “diet” must flip into “maintenance”—and a simple sign you're ready The smallest daily tweak from his research that predicts whether you'll regain or not What exercise actually changes in your metabolism beyond calorie burn—and how much you really need The simple resistance-training + protein formula he gives midlife women to keep muscle while losing fat His three-bucket framework (diet, activity, mind state) and a 60-second self-check to find which bucket is breaking your results The mindset shift that moves people from “I always regain” to “this is who I am” — plus a quick exercise to uncover your real why The step-by-step exit plan he uses when patients come off GLP-1s—starting with what to do in week one to avoid rebound If you've ever lost weight and struggled to keep it off, this episode shows you which levers matter most—and how to pull them so your results stick while your metabolism and muscle thrive. Get delicious high protein meal recipes! Connect with Vanessa on Instagram @ketogenicgirl Free High-Protein Keto Guide Get 20% off on the Tone LUX Crystal Red Light Therapy Mask or the Tone Device breath ketone analyzer at https://ketogenicgirl.com with the code VANESSA Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast Mentioned in this episode: • Dr. James Hill's upcoming book: Losing the Weight Loss Meds: A 10-Week Playbook for Stopping GLP-1 Medications and Keeping the Weight Off — now available for pre-order • The National Weight Control Registry; The Diabetes Prevention Program (DPP); The Look AHEAD Study; The Beef WISE Study The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.
In this episode of the Metabolic Mind podcast, Dr. Bret Scher speaks with L.J. Amaral, a registered dietitian, certified in nutrition oncology, and PhD student researcher at Cedars-Sinai, about where ketogenic therapy may fit into cancer care. Together they emphasize a crucial point: in oncology, we're not just treating the tumor, we're treating the whole person. The quality of life, physical strength, and day-to-day function of patients matter in prognosis.L.J. covers:How shifting fuel toward ketones may influence metabolism, inflammation, fatigue, and even muscle preservation during treatment.Why many tumors crave glucose, and why that matters for dietary strategies.The potential of ketogenic therapy used alongside standard of care (surgery/chemo/radiation), with early signals around feasibility, daily living, and patient well-being.The real-world nuance of responders vs. non-responders, and why personalized coaching is key.How some patients pair fasting windows with treatment, and the practical safeguards to consider.What's next: details on an NIH-funded, multi-center phase 2 trial comparing a ketogenic approach to an American Cancer Society–style diet.Ketogenic therapy in oncology is early but advancing. If you're curious about science-backed nutrition strategies that support both treatment and daily life, this conversation is for you.
Beat BLOAT & unlock better protein absorption and digestion with MassZymes by BiOptimizers. NOW GET 15% off your order with the code VANESSA at bioptimizers.com/vanessa In this solo episode, Vanessa breaks down her in-depth conversation with Dr. Emily Lantz, a leading researcher in protein metabolism and muscle physiology. Discover why eating around 30 g of high-quality protein at each meal may be the key to preserving lean muscle, optimizing metabolism, and aging stronger—especially for women through perimenopause and beyond. Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa Vanessa also unpacks the research on protein distribution (30-30-30), sleep as an anabolic signal, and how to protect your muscle during rapid fat loss, translating cutting-edge science into practical steps you can use today. What You'll Learn The science behind the 30-30-30 protein rule and why it matters for women How sleep loss can lower muscle protein synthesis by up to 20% What studies reveal about plant vs. animal protein for glucose control and satiety The truth about “wasted” protein and how much you really need per meal How to minimize muscle loss during fat loss or menopause A simple 3-meal template to optimize body composition and strength
Send us a textMax Helmer is a former CrossFit gym owner, lifelong athlete, and host of The Low Carb Consultant Podcast.After years of battling chronic dieting, rapid weight fluctuations, and inflammatory health issues, Max discovered the power of low-carb nutrition and intermittent fasting in 2018—transformations that reshaped both his health and his perspective.Today, he interviews leading doctors, athletes, and coaches to uncover the most effective strategies for health, longevity, and performance, bringing practical and science-backed insights to his audience.Based in Texas with his wife and two children, Max balances podcasting and content creation with his passions for cooking, meal prepping, training in his garage, and spending time with family. His mission is simple: help others cut through the noise and discover what truly works for sustainable health and performance.Find Max at-IG @thelowcarbconsultantPodcast- The Low Carb Consultant PodcastYT @Max Helmer The Low Carb ConsultantFind Boundless Body at- myboundlessbody.com Book a session with us here!
In this episode of Better Thinking, Nesh Nikolic speaks with Professor Zoltán Sarnyai about his recent randomized controlled trial on ketogenic metabolic therapy for serious mental illness and the broader implications of this emerging field for the future of psychiatric treatment.Professor Zoltán Sarnyai, Director of the Margaret Roderick Centre for Mental health Research at James Cook University, is a medically trained neuroscientist with an internationally recognised expertise in the neurobiology of stress and mental health disorders. Before moving to Australia, he was University Lecturer in the Department of Pharmacology, University of Cambridge and a Fellow of Pembroke College, where he was Director of Studies for Medicine. He trained at McLean Hospital at Harvard Medical School and at The Rockefeller University, supported by the DuPont-Warren Award and a NARSAD Young Investigator Award, respectively. His group described the role of stress neuropeptides oxytocin and corticotropin-releasing factor in addiction, for which he was awarded the Richter Prize by the International Society of Psychoneuroendocrinology. More recently, he discovered the efficacy of ketogenic metabolic therapy in preclinical models of schizophrenia and is currently conducting the world's first randomised controlled clinical trial to investigate this in clinical populations. Zoltán was appointed Lady Davis Visiting Professor at Technion-Israel Institute of Technology to study the neuro- metabolic aspects of schizophrenia. Zoltan has published over 150 original research papers, reviews and book chapters, his works have been cited over 10,000 time, with an H index of 50. He is Associate Editor for Nutritional Neuroscience and Frontiers in Neuroscience, and editorial board member of Nutritional Psychiatry and Stress.
Welcome to The Superhumanize Podcast. I'm your host, Ariane Sommer, and today we're diving into one of the most paradigm-shifting conversations in modern medicine: the metabolic theory of cancer.For decades, we've been told that cancer is primarily a genetic disease, a matter of unlucky mutations that require aggressive pharmaceutical interventions. But what if that's only part of the story? What if cancer is fundamentally a metabolic disease, a disorder of cellular energy production that we can address through diet, lifestyle, and targeted metabolic therapies?This isn't fringe science. And it's giving patients new hope, and new options, beyond the standard cut, poison, and burn model. Today, I'm thrilled to welcome Dr. Donese Worden to the show. Dr. Worden is a board-certified Naturopathic Medical Doctor, researcher, and global health educator who has dedicated her career to bridging conventional and alternative cancer care. She's collaborated with Banner MD Anderson Cancer Center, served as CEO of Care Oncology, and works directly with Dr. Seyfried on metabolic cancer research. She's also the creator of the 7 Pillars of Health framework, a comprehensive approach to resilience that addresses everything from sleep and gut health to spiritual wellbeing.Dr. Worden's motto is 'Educate, Empower, Enlighten,' and that's exactly what we're going to do today. We'll explore the metabolic theory of cancer, discuss both prevention and treatment strategies, and give you a roadmap for building resilience at every level.Episode Highlights00:00 Welcome + why the “metabolic theory of cancer” matters02:00 Genetics vs. metabolism: why only ~5% is strictly genetic (and gene expression is modifiable)03:45 Warburg's mitochondrial lens; PET scans lighting up because cancer voraciously consumes sugar06:45 How we veered away historically; incentives that kept oncology gene-centric09:00 What damages mitochondria today: toxins, antibiotics (without mitigation), chronic stress10:30 Stress as a metabolic driver; why it keeps glucose high even on a “good” diet12:30 Ketogenic therapy for cancer: high fat, lower protein (individualized), carbs mainly from veggies15:00 Measuring correctly: Keto-Mojo, GKI (Glucose-Ketone Index); skip urine strips for accuracy17:00 Fast stress relief protocols: music-guided entrainment, breath work, active meditation, journaling20:15 Somatic breath work in practice; rapid emotional release21:00 Best fats and how Dr. W screens with food-sensitivity testing first23:15 Keto cycles for prevention: 6-week blocks a couple times per year24:15 Exercise as mitochondrial medicine: HIIT + resistance for biogenesis and cancer risk reduction26:00 The KetoPet model: ketogenic diet + HBOT + interval training; lessons for humans28:15 Starting movement in late-stage cases; meeting people exactly where they are30:15 “Press–Pulse” strategy: what stays constant vs. what's pulsed to outsmart tumor adaptation32:00 Repurposed meds (e.g., metformin, doxycycline) and why many oncologists can't step outside SOC33:00 Bridging care: when surgery/chemo/radiation have a role; aiming at cancer stem cells37:15 Hyperbaric oxygen therapy (HBOT): driving O₂ into cells; why it's pulsed and protocol-specific39:30 Outcomes Dr. W sees most consistently: better quality of life, often longer survival41:00 The psychology of prognosis; belief, stress, and manifestation43:00 The “placebo” as your body's own pharmacy (parasympathetic healing state)44:15 Targeting glutamine along with glucose; where evidence stands now (e.g., berberine, exercise, stress)46:45 The Seven Pillars of Health overview (self-audit)48:30 Pillar 1 — Sleep: deep/REM, how you feel on waking49:15 Pillar 2 — Body: strength,...
NEW! Support your strength and muscle goals with PUORI Creatine+ — a clean, effective creatine monohydrate supplement enhanced with magnesium and vitamin B12. Get 20% off at puori.com/VANESSA Can you really lose fat without losing muscle? Vanessa sits down with Dr. Guillermo Escalante, physique competitor and sports nutrition researcher, to reveal the science of doing exactly that. Learn how high-protein diets and refeeds can preserve lean mass, reignite a slowed metabolism, and make fat loss more sustainable. Dr. Escalante shares evidence-backed insights from his own research and contest experience on how to optimize protein intake, structure refeeds, and achieve real body recomposition—without the extremes. OneSkin is powered by the breakthrough peptide OS-01, the first ingredient proven to reduce skin's biological age. I use the OS-01 Face and Eye formulas daily—they've transformed my skin's smoothness, firmness, and glow. Visit oneskin.co/VANESSA and use code VANESSA for 15% off your first purchase Unlock sharper focus and support long-term brain health with Ketone-IQ—clean brain fuel for deep work, mental clarity, and sustained energy with no crash. Get 30% off your subscription, plus a free gift with your second shipment at Ketone.com/vanessa. Get delicious high protein meal recipes! Connect with Vanessa on Instagram @ketogenicgirl Free High-Protein Keto Guide Get 20% off on the Tone LUX Crystal Red Light Therapy Mask or the Tone Device breath ketone analyzer at https://ketogenicgirl.com with the code VANESSA Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.
In this powerful educational episode, Vanessa sits down with Oliver Amdrup-Chamby, CEO and Co-Founder of Puori, for an in-depth masterclass on the supplements most overlooked—yet most transformative—for women's health: creatine and omega-3s. Drawing on the latest scientific research and insights from world-leading muscle and metabolism experts, Vanessa and Oliver unpack: ✅ Why creatine is a foundational supplement for women—supporting fat loss, body recomposition, muscle preservation, and cognition ✅ How creatine protects metabolism and lean mass during fat loss ✅ The truth about “water retention” and bloating myths ✅ How creatine supports menopause, bone density, and strength across the lifespan ✅ The emerging research on brain and mood benefits of creatine ✅ Why omega-3s are critical for inflammation, recovery, metabolic health, and brain function ✅ How creatine and omega-3s synergize for performance and longevity Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa Then, in the final third of the conversation, they address one of the most pressing issues in the supplement industry today: purity and contamination. Vanessa and Oliver discuss: ⚠️ Why heavy metals like lead have been found in popular protein powders and prenatal vitamins ⚠️ What “safe levels” actually mean ⚠️ How consumers can protect themselves by choosing transparent, third-party tested products ✅ How Puori leads the industry with Clean Label Project certification, testing for over 200 contaminants, and QR codes that let you view your batch's lab results instantly This episode is a must-listen for women who want to take their health, fat loss, and longevity to the next level—using the cleanest, most evidence-based supplements available. Beat BLOAT & unlock better protein absorption and digestion with MassZymes by BiOptimizers. NOW GET 15% off your order with the code VANESSA at bioptimizers.com/vanessa Mentioned in This Episode: • Puori Creatine+ — use code VANESSA for 20% off, including subscriptions • Creatine Supplementation in Women's Health: A Lifespan Perspective • Puori Omega-3 testing & Clean Label certification Get my NEW high-protein keto guide: The Keto Reset eBook Learn more about the TONE LUX Crystal red light therapy mask and the accessory the TONE LUX CONTOUR for the neck and décolleté and get 20% OFF with the code VANESSA Free high-protein keto guide: The Keto Reset eBook
A meta-analysis of low-carb diets for diabetes remission found little to no effect at 12 months, clinically important harms to quality of life, and the deal-killer––an increase in LDL cholesterol.
Unlock sharper focus and support long-term brain health with Ketone-IQ—clean brain fuel for deep work, mental clarity, and sustained energy with no crash. Get 30% off your subscription, plus a free gift with your second shipment at Ketone.com/vanessa. In this episode, Vanessa sits down with Dr. Emily Lantz, Assistant Professor at the University of Texas Medical Branch and mentee of the late Professor Douglas Paddon-Jones, for a deep dive into how protein timing, distribution, and quality influence muscle health, fat loss, and long-term body composition. NEW! Support your strength and muscle goals with PUORI Creatine+ — a clean, effective creatine monohydrate supplement enhanced with magnesium and vitamin B12. Get 20% off at puori.com/VANESSA Dr. Lantz is one of the foremost researchers studying how nutrition and metabolism interact — from the 30/30/30 protein distribution model to the surprising effects of sleep deprivation on muscle protein synthesis. They discuss:
Ketogenic therapy is a powerful tool for weight loss. But not everyone who cuts carbs is able to achieve their goal weight and metabolic health goals. Could GLP-1s offer the missing piece when low-carb and clean eating aren't quite enough?In this episode of the Metabolic Mind Podcast, Dr. Bret Scher sits down with Dr. Shannon Robinson, a board-certified psychiatrist and addiction medicine specialist, to explore this overlooked population who could benefit most from GLP-1s. Drawing from both her personal journey and clinical practice, Dr. Robinson highlights why lifestyle alone isn't always enough, and how medications can sometimes be life-changing.In this conversation, you'll learn:✅ Why GLP-1s may help patients already following strict low-carb or carnivore diets✅ How keto (and GLP-1s) are beneficial for weight loss and addiction✅ The parallels between GLP-1s and addiction medicine✅ Real-world insights on side effects, dosing, and the impact of GLP-1s on muscle✅ Advice for people starting GLP-1 medications✅ Why controlling GLP-1 dose is importantFor many, food and lifestyle changes unlock better health. But when life's stressors and personal biology create roadblocks, other tools may be able to help. As Dr. Robinson highlights, GLP-1s aren't a replacement for a healthy lifestyle, but when strategically used in combination with lifestyle changes, they can be a key to success for many people.
Beat BLOAT & unlock better protein absorption and digestion with MassZymes by BiOptimizers. NOW GET 15% off your order with the code VANESSA at bioptimizers.com/vanessa In today's solocast, we break down a brand new clinical trial that tested whether a high-protein diet really shuts down autophagy — and what it means for fat loss and body composition. For years, many believed that eating more protein would block the body's cellular clean-up process, and that only low-protein fasting diets could deliver longevity benefits. But does the science actually back that up? This new randomized controlled trial put high-protein and low-protein diets head-to-head, measuring weight loss, belly fat, metabolic health, and markers of autophagy. The results may surprise you — and they could change how we think about protein for fat loss and longevity. Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa We'll explore: Why autophagy matters for health and aging How the trial compared high vs. low protein under calorie restriction What the researchers found on belly fat, IGF-1, and cellular clean-up What this means for your fat loss and body recomposition goals IQBAR — Brain + body nutrition bars with high protein and clean ingredients. Get 20% off all products by texting VANESSA to 64000. Get my NEW high-protein keto guide: The Keto Reset eBook Learn more about the TONE LUX Crystal red light therapy mask and the accessory the TONE LUX CONTOUR for the neck and décolleté and get 20% OFF with the code VANESSA Free high-protein keto guide: The Keto Reset eBook
Send us a textUrban A. Kiernan, Ph.D. has over 25 years of industry business and research experience that has spanned from diagnostics, biomarkers, sports antidoping and now into biopharmaceutical discovery.Dr. Kiernan is the Founder, Chairman and CEO of iMetabolic Biopharma Corporation (iMBP), an early stage TechBio company that is developing an innovative AI computational drug discovery technology, as well as an early stage drug pipeline with assets gearing towards the treatment of metabolic, cardiovascular and neuro-degenerative diseases.With one business exit under his belt, he has also been the recipient of almost $5M in NIH awards, holds 12 issued patents, authored ~50 peer reviewed publications and four book chapters.He is a husband and father of three (grandfather of one), as well as is the host of the Decoding Health Podcast. Even though he owns his own drug discovery company, he is an advocate for personal accountability and commitment to health and health span.For fun he holds a 2nd degree black belt in Judo and recently received his black belt in Brazilian Jiu Jitsu.Find Dr. Kiernan at-LK- Urban A. Kiernan, Ph.D.IG- @light_bearerYT- @DecodingHealthPodcasthttps://www.decodinghealthpodcast.com/Find Boundless Body at- myboundlessbody.com Book a session with us here!
Harvard MD/PhD Nick Norwitz reversed ulcerative colitis, lowered cholesterol with Oreos, and now exposes the cracks in modern medicine. This episode is a masterclass in metabolic rebellion and curiosity.Join the Kiltz Health Certification Course here: 50% DISCOUNT until 10/8/2025: https://buy.stripe.com/fZuaEYbJaeCp4Df2OY0480xJoin the Kiltz Mighty Tribe - It's free: https://kiltz-mighty-tribe.mn.co/0:00 – Nick's medical legacy and why he chose medicine 4:12 – Ulcerative colitis diagnosis and desperation-driven healing 8:45 – Ketogenic diet leads to full remission 12:30 – Why modern medicine fails chronic disease patients 16:05 – Incentives, pharma, and the business of healthcare 20:40 – Why RCTs don't reflect real-world healing 25:10 – Nutrition education gaps in med school 30:00 – GLP-1s, statins, and lifestyle vs. pharma 35:45 – Nick's grocery cart: what he actually eats 41:20 – Red meat and cancer myths 46:00 – The Oreo experiment: lowering LDL with cookies 50:30 – Empowering patients to lead their own health journey 54:00 – “Stay Curious”: Nick's mantra and tattoo 58:00 – Where to follow Nick Norwitz and final reflections
In this episode of the Ageless Future podcast, Cade Archibald interviews Matt Gallant, CEO and co-founder of BIOptimizers, to explore his multi-decade journey in health optimization. From experimenting with over 30 diets—including keto, vegan, carnivore, and raw food—to founding a supplement empire grounded in rigorous scientific research, Matt shares how his passion for performance and experimentation has shaped his mission to transform health. The conversation dives deep into cutting-edge supplementation, the development of a world-class biolab, and the power of neurofeedback as a tool for cognitive transformation. Matt also introduces his 10-day brain optimization program, Metamorphosis, designed to unlock higher levels of resilience, executive function, and consciousness. This episode is a masterclass in biohacking and personalized health optimization. Matt Gallant is a serial entrepreneur, the CEO and co-founder of BIOptimizers, a health author, and a kinesiologist with a degree in the Science of Physical Activity. He has also been a strength and conditioning coach for multiple pro athletes and a self-defense instructor. He co-formulated the Magnesium Breakthrough, among many other supplements over 18 years. He's tried virtually every diet once but has been successfully following a mostly ketogenic diet for over 30 years, and his purpose is to create life-changing health solutions. Matt recommends three of their products: Magnesium Breakthrough, Mushroom Breakthrough, and MassZymes, and offeres our Ageless Future listeners a 15% discount by visiting bioptimizers.com/agelessfuture!Instagram: https://www.instagram.com/bioptimizers/ Website: www.bioptimizers.comFacebook: https://www.facebook.com/BiOptimizers/YouTube: https://www.youtube.com/bioptimizersTikTok: https://www.tiktok.com/@bioptimizers
Send us a textJackie Fletcher is a returning guest on our show! Be sure to check out her first appearance on episode 539 of Boundless Body Radio!!Jackie Fletcher is a qualified Network Nutrition Adviser, Primal Health Coach and Health and Wellbeing Coach, specializing in metabolic health. Jackie started her ketogenic way of eating in January 2018.Jackie is committed to not only improving her own health and wellbeing, but to pay it forward to the wider community through her volunteering, health coaching and podcast. She is a former ambassador for the Public Health Collaboration, which is a registered charity focused on improving public health.As a health coach, she encourages, motivates and educates clients with a personalized approach to eating real food and a positive way of living. This message was central to her mission when she founded Fabulously Keto and The Fabulously Keto Podcast, which I was fortunate to be recently hosted on!Jackie lives in the UK with her husband and twin boys, she has a black belt in Taekwondo, and sometimes she can be found open water swimming, even in the winter!Find Jackie at-TW- @fabulouslyketoFB- @FabulouslyKetoIG- @fabulouslyketo1https://fabulouslyketo.com/Find Boundless Body at- myboundlessbody.com Book a session with us here!
Unlock sharper focus and support long-term brain health with Ketone-IQ—clean brain fuel for deep work, mental clarity, and sustained energy with no crash. Get 30% off your subscription, plus a free gift with your second shipment at Ketone.com/vanessa. In this powerful second interview, Dr. Latt Mansor returns to the podcast to share his personal 20+ lb fat loss transformation—and how he used ketones and strategic carb re-feeds to break through stubborn plateaus, curb hunger, and preserve lean muscle mass. NEW! Support your strength and muscle goals with PUORI Creatine+ — a clean, effective creatine monohydrate supplement enhanced with magnesium and vitamin B12. Get 20% off at puori.com/VANESSA We dive into: How to use ketones to improve fat loss quality (not just scale weight) Why Dr. Mansor says ketones helped him “lose fat without losing muscle” How carb re-feeds helped him overcome plateaus and support metabolic flexibility How ketones support appetite control, recovery, and training performance A new study showing ketones boost sprint output and reduce fatigue Ketones vs. GLP-1 drugs like Ozempic—how they compare for appetite suppression Dosing protocols for fat loss, fasting, and late-night cravings How ketones improve oxygen delivery, red blood cell production, and reduce cortisol The science behind ketones reducing muscle protein breakdown and supporting performance Ketones and the brain: supporting focus, anxiety, ADHD, and GABA signaling If you've hit a fat loss plateau—or want to preserve muscle while losing fat—this episode is packed with cutting-edge science and tools on how to use exogenous ketones and strategic carbs to support metabolic health, performance, and sustainable results. Connect with Vanessa on Instagram @ketogenicgirl Free High-Protein Keto Guide Get 20% off on the Tone LUX Crystal Red Light Therapy Mask or the Tone Device breath ketone analyzer at https://ketogenicgirl.com with the code VANESSA Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.
Ketogenic therapy for mental illness is gaining attention, with more and more patients looking to incorporate this strategy into their care plan.The problem is that sometimes patients struggle to find providers to help them and providers often lack the expertise and confidence to prescribe this strategy.These issues led to a light bulb moment for Dr. Kelly, “We've got to capacity build, we have to figure this out.”In this interview, Dr. Bret Scher speaks with Deanna Kelly, PharmD, internationally recognized for her work in schizophrenia, psychiatric pharmacology, and metabolic health, who is now pioneering an innovative project of her own called Live it, Launch it.This first-of-its-kind study is Dr. Kelly's brainchild, designed to train clinicians through direct experience in an effort to increase clinical expertise in metabolic and ketogenic therapies. Participants don't just learn the science, they actually live a ketogenic diet themselves, gaining confidence, competence, and practical insight to better guide patients struggling with psychiatric disorders.In this interview, you'll discover:Why so many families are searching for trained ketogenic therapy cliniciansWhy personal experience may be the missing link in clinical adoptionThe potential widespread clinical impact of Live it, Launch it.The potential of ketogenic therapy alongside medications like GLP-1sAn update on Dr. Kelly's in-patient ketogenic therapy for schizophrenia studyBy training clinicians to live it before they launch it, this study could change how psychiatric care is delivered, and help meet the growing demand for clinical guidance in ketogenic therapy.Expert Featured:Dr. Deanna KellyDirector of the Maryland Psychiatric Research CenterX: https://x.com/profdeannakResources Mentioned:Why Did the Maryland Health Department Halt a Critical Schizophrenia Study?https://youtu.be/tzPlQ6dJwe8Stanford Study Shows Promise of Ketohttps://www.metabolicmind.org/trials/featured/stanford-study-shows-promise-of-keto/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits:https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of...
Send us a textToday we are releasing another bonus episode! This is my second and most recent appearance on The Fabulously Keto Podcast hosted by Jackie Fletcher!As always, it was a fun chat, and I'm always so grateful to be a guest on someone else's show!Find Jackie at-TW- @fabulouslyketoFB- @FabulouslyKetoIG- @fabulouslyketo1https://fabulouslyketo.com/Find Boundless Body at- myboundlessbody.com Book a session with us here!
Beat BLOAT & unlock better protein absorption and digestion with MassZymes by BiOptimizers. NOW GET 15% off your order with the code VANESSA at bioptimizers.com/vanessa Today's solocast is all about Protein-Sparing Modified Fast (PSMF) days — how I've been using them in my own fat loss journey, how my approach differs from the traditional PSMF, and what the latest research says about PSMF, refeeds, and protein intake for protecting lean mass. IQBAR is offering our special podcast listeners 20% OFF all IQBAR products, plus get FREE shipping. To get your 20% off, text VANESSA to 64000. That's VANESSA to sixty-four thousand. Message and data rates may apply. See terms for details. I'll be sharing: Exactly how I structure PSMF days for myself, including my research based updates on the method How I base my approach on cutting-edge research, including the brand-new 2025 meta-analysis on protein intake and lean mass preservation during fat loss My personal results so far — how much weight I've lost since starting August 1, how it's affecting my body composition, and what's working best for me The latest studies on PSMF and refeed protocols: do refeeds really help with fat loss or just with muscle preservation and diet fatigue? Why pushing protein higher during a cut is “muscle insurance” and what the evidence says is the sweet spot for most women and men If your goal is fat loss without losing muscle, this episode is your blueprint. Get my NEW high-protein keto guide: The Keto Reset eBook Learn more about the TONE LUX Crystal red light therapy mask and the accessory the TONE LUX CONTOUR for the neck and décolleté and get 20% OFF with the code VANESSA Free high-protein keto guide: The Keto Reset eBook
In this episode of The Heart to Heart podcast, host Dr. Mike Hart interviews Alex Leaf, an independent nutritional researcher renowned for debunking nutritional misinformation on social media. The discussion covers topics such as the benefits of collagen for skin health, the potential advantages of ketogenic diets for athletes, and the truth behind various nutrition myths including the effects of soy on testosterone and semen retention. Alex also shares his insights on intermittent fasting, ideal protein intake, and the debate over seed oils. The conversation concludes with their thoughts on cardiovascular health markers and the relevance of particle size in LDL cholesterol. Alex Leaf is an independent nutritional researcher, scientific communicator, and educator specializing in human health and performance. With a decade of experience translating complex science into actionable insights, Alex rose to prominence as a researcher and writer at Examine.com before joining Ari Whitten's Energy Blueprint. His work spans peer-reviewed publications—including contributions to the ISSN position stand on ketogenic diets—and teaching in the Master's program in Human Nutrition and Functional Medicine at the University of Western States. Follow him here: Website: alexleaf.com Instagram: @AlexJLeaf Links: IVF and Abstinence Studies Systematic Review on Ketogenic Diets in Athletes Whey Protein vs. Beef Protein Show Notes: 00:00 – Welcome back to the Hart2Heart Podcast with Dr. Mike Hart 02:30 – Collagen and skin health 08:30 – Ketogenic diets for athletes 14:00 – Protein intake for athletes 18:00 – Intermittent fasting vs caloric restriction 25:00 – Seed oils: myths and facts 30:00 – Semen retention: debunking the myths 35:00 – Soy and hormones 38:30 – Soy consumption and hormonal effects 39:30 – Whey protein: benefits and misconceptions 42:30 – Post-workout nutrition myths 45:00 – Insulin sensitivity and carbohydrate timing 54:00 – Protein intake strategies 57:00 – Calories and diet composition 57:14 – “A calorie is a calorie, but depending on your diet's composition, you'll absorb and utilize very different amounts of calories from food.” 01:01:00 – Debating dietary approaches 01:05:00 – Cardiovascular health markers 01:12:00 – Conclusion and contact information — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to cutting through the noise and uncovering the most effective strategies for optimizing health, longevity, and peak performance. This podcast dives deep into evidence-based approaches to hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary. Beyond health science, we tackle the intersection of public health and politics, exposing how Policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being. Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen). If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being. Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart
Content Note / Trigger Warning: The first two-thirds of this episode focus on Maria Emmerich's expertise in helping thousands of people who are overweight, obese, or struggling with metabolic health to lose weight and dramatically improve their health and lives. In the last third of the interview, Maria shares her very recent personal experience with struggling with restrictive dieting, and her courageous journey of weight regain. Please listen with care if these topics around disordered eating may be sensitive or triggering for you. See *RESOURCE below if you or someone you care about needs support. Unlock sharper focus and support long-term brain health with Ketone-IQ—clean brain fuel for deep work, mental clarity, and sustained energy with no crash. Get 30% off your subscription, plus a free gift with your second shipment at Ketone.com/vanessa. Today's guest is Maria Emmerich, internationally renowned nutritionist, best-selling author, and an expert in her version of integrating 1-2 Protein Sparing Modified Fast Days (PSMF Days) in a week to create a weekly caloric deficit while protecting muscle and metabolism, including re-feed days to balance out the week. In this episode, we cover: What PSMF Days are and how they differ from the sugar diet or fasting How PSMF Days preserve lean muscle while accelerating fat loss The role of stall foods like nuts, dairy, and nut flours in holding back fat loss Client strategies for satiety, electrolytes, and exercise integration The science behind metabolic adaptation, and refeeds Why higher protein intake and supplements like creatine are key for recomposition Maria's personal story of becoming too lean, regaining weight, and how it reshaped her coaching philosophy This episode is packed with practical strategies from Maria's decades of experience helping people transform their health — and also offers a very candid look into her own personal journey. IQBAR is offering my podcast listeners 20% OFF all products, plus FREE shipping! IQBARs are packed with plant protein, fiber, and brain nutrients like Lion's Mane and omega-3s, keto-friendly, low in sugar, gluten-free, dairy-free, and soy-free. To claim your discount, just text VANESSA to 64000. That's VANESSA to sixty-four thousand. Message and data rates may apply. See terms for details. NEW! Support your strength and muscle goals with PUORI Creatine+ — a clean, effective creatine monohydrate supplement enhanced with magnesium and vitamin B12. Get 20% off at puori.com/VANESSA Connect with Vanessa on Instagram @ketogenicgirl Free High-Protein Keto Guide Get 20% off on the Tone LUX Crystal Red Light Therapy Mask or the Tone Device breath ketone analyzer at https://ketogenicgirl.com with the code VANESSA Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen. *RESOURCE: If you are in the United States and you or someone you love is struggling with disordered eating, support is available. You can call the National Eating Disorders Association (NEDA) Helpline at 1-800-931-2237 or visit nationaleatingdisorders.org for resources.
Beat BLOAT & unlock better protein absorption and digestion with MassZymes by BiOptimizers. NOW GET 15% off your order with the code VANESSA at bioptimizers.com/vanessa In this special solocast, Vanessa recaps the top highlights from two powerhouse researchers in protein metabolism: Dr. Carlene Starck and Dr. Arny Ferrando. If your goal is fat loss, muscle preservation, and body recomposition—especially in peri and post-menopause—this episode is packed with evidence-based strategies you can start applying today. IQBAR is offering our special podcast listeners 20% OFF all IQBAR products, plus get FREE shipping. To get your 20% off, text VANESSA to 64000. That's VANESSA to sixty-four thousand. Message and data rates may apply. See terms for details.
In this week's episode of The Best Guest podcast we welcome The Brain Energy Reboot Expert, Moira Newiss.We talk about:Ketogenic & Metabolic Mental HealthMitochondria, Brain Energy & FatigueAutoimmune Conditions & the Carnivore DietAbout Moira NewissMoira Newiss is a BANT registered nutritional therapist, health coach and accredited ketogenic metabolic therapy expert who specialises in brain energy, one of the recently discovered root causes of many mental health problems.Moira's passion for metabolic mental health was sparked after a 20-year career as a senior NHS manager, managing hundreds of staff and multi-million-pound budgets. Following burnout, chronic fatigue and mental illness, she retrained at the Institute for Optimum Nutrition and became fascinated by the link between energy, mood, mental health and metabolic health. Moira works with individuals who have conditions including depression, anxiety, bipolar disorder, and schizophrenia, who have often not found a resolution with medication or psychological support alone. Her personalised approach has helped hundreds to improve their symptoms, with some achieving full remission, that means reversal, of their condition.A regular conference speaker, Moira co-authored the first mental health guidelines for nutritional therapists and published the case report ‘Remission of Schizophrenia Using a Carnivore Ketogenic Metabolic Therapy with Nutritional Therapy Practitioner Support'.Moira is lucky to live on the beautiful west coast of Scotland where she has a large garden, grows her own fruit and vegetables and has a lovely flock of hens. She also loves adventure, regularly climbing mountains, bike packing and hiking in remote spots on short expeditions. Key TakeawaysFor some people, shifting from glucose to ketone fuel can rapidly improve brain fog, mood, and energy.Common keto pitfalls include undereating fat and overeating proteinSleep, morning light, reduced evening blue light, and gentle movement support brain energy and mood.Short-term carnivore diet can be a powerful elimination protocol to calm inflammation, heal the gut and identify food triggers.Dairy-free keto is doable - use coconut fats, olive oil, tallow/lard, fatty fish; check labels on “milks” for hidden carbs.QuoteI had planned to do a hundred kilometre bike ride, and I remember crossing the finishing line thinking—and I was crying 'cause it was just an emotional thing—I just knew I cracked it. I just knew the energy was there. I'd cycled a hundred kilometres with no carbohydrates.Connect with Moira NewissWebsite: https://www.moiranewiss.co.uk/ Instagram: https://www.instagram.com/moiranewiss LinkedIn: https://www.linkedin.com/in/moira-newiss/ YouTube: https://www.youtube.com/@moiranewiss Connect with Victoria BennionLearn more about us: https://thebestpodcastguest.co.uk/Download our Podcast Guest Starter Kit: The Podcast Guest Starter Kit gives you a proven plan to find the right shows, craft a winning pitch, and maximise every interview.
Unlock sharper focus and support long-term brain health with Ketone-IQ — clean brain fuel for deep work, mental clarity, and sustained energy with no crash. Get 30% off your subscription, plus a free gift with your second shipment at Ketone.com/vanessa. In this highly requested follow-up, Dr. Arny Ferrando returns to the Optimal Protein Podcast to go even deeper into the science of preserving muscle and optimizing body composition. Dr. Ferrando is one of the world's leading researchers in muscle protein metabolism, with over 35 years of groundbreaking work on essential amino acids, anabolic resistance, and nutrition-exercise interactions. We kick things off with his perspective on Protein-Sparing Modified Fasts (PSMF) versus water fasting, and the implications each has for fat loss and lean mass preservation. Dr. Ferrando also shares his positive take on collagen supplementation, including how it can support connective tissue health, and weighs in on the potential risks of GLP-1 medications to muscle tissue during rapid weight loss. NEW! Support your strength and muscle goals with PUORI Creatine+ — a clean, effective creatine monohydrate supplement enhanced with magnesium and vitamin B12. Get 20% off at puori.com/VANESSA We kick things off with his perspective on Protein-Sparing Modified Fasts (PSMF) versus water fasting, and the implications each has for fat loss and lean mass preservation. Dr. Ferrando also shares his positive take on collagen supplementation, including how it can support connective tissue health, and weighs in on the potential risks of GLP-1 medications to muscle tissue during rapid weight loss. The heart of this episode dives into anabolic resistance during menopause. Dr. Ferrando explains why it may not just be about hormones, but also about impaired nutrient delivery to muscle. He describes amino acids as the “signal” and blood flow as the “delivery truck”—a powerful analogy that reveals why exercise is so critical to overcoming anabolic resistance. We explore practical strategies for women to preserve muscle and improve body composition during midlife and beyond, including: Why blood flow and nutrient delivery may matter as much as hormones. How red light therapy and blood flow restriction training (BFR) could enhance amino acid delivery and muscle responsiveness. His recommendations for EAA dosing, timing, and frequency in peri- and postmenopausal women. The role of microvascular health and endothelial function in muscle retention. Why free-form EAAs are more efficient than intact protein under calorie restriction. This conversation is packed with actionable science and myth-busting insights that will help you understand how to protect your muscle, burn fat, and stay strong at every stage of life. Connect with Vanessa on Instagram @ketogenicgirl Free High-Protein Keto Guide Get 20% off on the Tone LUX Crystal Red Light Therapy Mask or the Tone Device breath ketone analyzer at https://ketogenicgirl.com with the code VANESSA Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.
Unlock better protein absorption and digestion with MassZymes by BiOptimizers. NOW GET 15% off your order with the code VANESSA at bioptimizers.com/vanessa The Bloating Episode! If you've ever struggled with bloating after eating, digestive discomfort, or wondered if your body is really absorbing all the protein and nutrients you consume, this episode is for you. I'm joined by Wade Lightheart, co-founder and president of BiOptimizers, to dive into the science of digestive enzymes and how they can transform digestion, nutrient absorption, and protein utilization. A former natural bodybuilding champion, Wade developed MassZymes after struggling with his own digestion on a high-protein diet. We cover: What EXACTLY causes bloating and poor protein digestion Why low stomach acid and declining enzyme levels with age can cause bloating and poor nutrient absorption. Clinical research on protease blends and a 2024 protein study showing improved amino acid absorption with enzyme support. A university laboratory test on MassZymes suggesting over 1,200% more amino acids released compared to digestion alone. How lipase enzymes can reduce bloating and fullness after high-fat meals. Why older adults and high-protein eaters may especially benefit from enzyme supplementation for muscle and metabolic health. If bloating, slow digestion, or protein absorption has ever held you back from feeling your best, this conversation will help you fix your bloat and unlock the full benefits of your nutrition.
Unlock sharper focus and support long-term brain health with Ketone-IQ — clean brain fuel for deep work, mental clarity, and sustained energy with no crash. Get 30% off your subscription, plus a free gift with your second shipment at Ketone.com/vanessa. Today's episode features Dr. Carlene Starck, a nutrition scientist whose groundbreaking research is changing the way we think about protein and amino acid requirements. Her work suggests that current recommendations for essential amino acids may be far too low, with major implications for fat loss, muscle preservation, and how we define protein quality. NEW! I love Puori for their pure, science-backed supplements. Creatine+ is one of my top recommendations for women, as it's a foundational supplement that supports fat loss, body recomposition, lean muscle, and even cognition. Get 20% off at puori.com/VANESSA We discuss her research on: Why true protein and amino acid needs are higher than guidelines suggest How this widens the gap between animal and plant-based proteins The impact of gut and oxidative amino acid losses on protein requirements Novel strategies to improve protein digestion, from kiwifruit enzymes to keratin hydrolysates Dairy vs. plant alternatives, and what her latest A2 milk study revealed about mood and cognition Affordable ways to close key nutrient gaps for better body composition and health Dr. Starck also shares a preview of her upcoming work on protein requirements and what it means for the future of nutrition science. This is a must-listen episode if you want to understand why protein is so central to fat loss, metabolic health, and long-term body recomposition. Connect with Vanessa on Instagram @ketogenicgirl Free High-Protein Keto Guide Get 20% off on the Tone LUX Crystal Red Light Therapy Mask or the Tone Device breath ketone analyzer at https://ketogenicgirl.com with the code VANESSA Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.
IQBAR is offering our special podcast listeners 20% OFF all IQBAR products, plus get FREE shipping. To get your 20% off, text VANESSA to 64000. That's VANESSA to sixty-four thousand. Message and data rates may apply. See terms for details. In this solo recap episode, Vanessa breaks down her in-depth interview with Dr. Andy Galpin, one of the world's leading muscle scientists and performance physiologists. This 60-minute masterclass distills the most important takeaways from their conversation into clear, actionable steps for fat loss, body recomposition, and metabolic health.
Dr. Dominic D'Agostino (@DominicDAgosti2) is a tenured associate professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine and a Visiting Senior Research Scientist at the Institute for Human and Machine Cognition.This episode is brought to you by: Helix Sleep premium mattresses: https://HelixSleep.com/Tim (27% off all mattress orders)Momentous high-quality creatine: https://livemomentous.com/tim (code TIM for up to 35% off)AG1 all-in-one nutritional supplement: https://DrinkAG1.com/Tim (1-year supply of Vitamin D plus 5 free AG1 travel packs)Timestamps:[00:00:00] Start.[00:14:43] Why I'm interested in ketogenic strategies for neurodegenerative prevention.[00:16:18] Mary and Steve Newport's ketone-linked temporary cognitive improvements.[00:18:18] A mechanisms overview for Alzheimer's/dementia.[00:21:25] The immune system as longevity's "fifth horseman" — and why metabolic control is key.[00:22:04] How to measure ketones and GKI.[00:23:00] Fasting vs. ketogenic diet.[00:24:18] There's nothing fishy about sardine fasting.[00:28:32] My hiatal hernia discovery and increased cancer risk concerns.[00:30:04] HSCRP as a superior biomarker to LDL for cardiovascular risk.[00:31:57] Glucose tolerance testing revelations and CGM importance.[00:31:57] Upgrading the metabolic machinery through keto without getting bored.[00:42:07] What do do if you, like Dom and me, are among the 30% who suffer from cholesterol hyperabsorption.[00:43:42] Dom's day-to-day diet regimen.[00:45:56] How Dom optimizes his aging dogs with ketones, SARMs, and supplements.[00:51:30] Supplementing for sleep disruption while fasting.[00:55:41] Why Dom doesn't have misgivings about melatonin.[00:59:15] Shingles prevention through fasting protocols.[01:00:15] Immune system modulation: Innate vs. adaptive, vegan vs. ketogenic.[01:03:54] Dom at 50-something: Current meal timing and composition.[01:05:57] Blue zone observations: Greek and Sardinian longevity habits.[01:08:16] Ketogenic diet initiation tips: MCT, electrolytes, and fasted cardio.[01:15:18] Ketone metabolic therapy for cancer.[01:18:15] The metabolic psychiatry revolution.[01:22:10] The soothing effects of hyperbaric oxygen and ketosis on seizure sufferers.[01:28:27] Metformin vs. berberine.[01:31:43] The low-dose neuroprotective potential of GLP-1 drugs.[01:34:58] NAD research: MIB-626 and stabilized forms for mitochondrial health.[01:39:48] Idebenone, CoQ10, and the Deanna protocol for ALS.[01:42:05] Dom's supplement short list: CoQ10, creatine, ketones, vitamin D, melatonin.[01:44:43] KetoNutrition.org, Metabolic Health Summit, Audacious Nutrition, veteran-focused research protocols, and other parting thoughts.*Show notes for this episode: https://tim.blog/2025/09/03/dr-dominic-dagostino-all-things-ketones/For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Unlock sharper focus and support long-term brain health with Ketone-IQ — clean brain fuel for deep work, mental clarity, and sustained energy with no crash. Get 30% off your subscription, plus a free gift with your second shipment at Ketone.com/vanessa. In this episode of the Optimal Protein Podcast, I'm joined by Dr. Andy Galpin — world-renowned muscle physiologist, strength coach, and leading expert in human performance optimization. We dive deep into the cutting-edge science of muscle, metabolism, fat loss, and how to train smarter at every stage of life. NEW! Support your strength and muscle goals with PUORI Creatine+ — a clean, effective creatine monohydrate supplement enhanced with magnesium and vitamin B12. Get 20% off at puori.com/VANESSA This conversation covers the latest research on muscle fiber types, how to maintain fast-twitch muscle into your 40s and beyond, and why many women are far more predisposed to strength and power than we've been led to believe. Dr. Galpin also shares actionable strategies to break out of fat loss plateaus, reverse chronic dieting, improve metabolic flexibility, and strategically use tools like intermittent fasting, pre-sleep protein, and creatine to maximize fat loss and muscle retention. You'll learn: What actually happens to fat when you lose it (hint: it leaves your body when you exhale!) Why most people are eating way less protein than they think — and how that sabotages recomposition The truth about sarcoplasmic vs. myofibrillar hypertrophy How to train if you're stuck at 1200 calories and not seeing progress The surprising impact of sleep on fat metabolism and why pre-sleep protein may boost your overnight fat burning How to use your circadian rhythm to schedule workouts for maximum performance What Dr. Galpin recommends if your peak energy window is in the late afternoon — including ideal wake-up and bedtimes Whether Pilates, intermittent fasting, or creatine actually work for fat loss and muscle building And how women can use strength training to build muscle, reverse aging, and become “metabolically bulletproof” If you're looking to overcome metabolic resistance, finally see results from your fat loss efforts, and train in a way that respects your biology — this episode is a masterclass in practical, science-backed strategies from one of the top experts in the world. Connect with Vanessa on Instagram @ketogenicgirl Free High-Protein Keto Guide Get 20% off on the Tone LUX Crystal Red Light Therapy Mask or the Tone Device breath ketone analyzer at https://ketogenicgirl.com with the code VANESSA Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.
In this episode of Unstress Health with Dr. Ron Ehrlich, psychiatrist and educator Dr. Matt Bernstein shares groundbreaking insights on the connection between nutrition, metabolism, and mental health. From his personal family journey through PANS/PANDAS and Lyme disease to pioneering holistic mental health programs at Accord, Dr. Bernstein explains how diet, lifestyle, and circadian rhythm alignment can radically transform psychiatric treatment. Mental health challenges affect over a billion people worldwide, yet conventional psychiatry often focuses only on symptom suppression. Dr. Matt Bernstein offers a refreshing approach, integrating metabolic health, ketogenic nutrition, and lifestyle medicine to help patients move beyond medication dependency and towards true healing. Together, Dr. Ron and Dr. Bernstein explore how food can be medicine, the science of ketones and brain health, and the four pillars of metabolic psychiatry: diet, exercise, mindfulness, and circadian rhythm alignment. Guest: Dr. Matt Bernstein Psychiatrist, educator & CEO of Accord, a residential program pioneering metabolic and holistic psychiatry Advocates for food as medicine, ketogenic interventions, and circadian alignment in mental health treatment Subscribe for More Insights Stay connected with valuable content by subscribing to Dr. Ron Ehrlich's YouTube channel: ▶ Subscribe Here: @doctorronehrlich Stay Connected with Dr. Ron Ehrlich Loved the content? Stay informed and join the conversation by following us on social media and exploring additional resources:
IQBAR is offering our special podcast listeners 20% OFF all IQBAR products, plus get FREE shipping. To get your 20% off, text VANESSA to 64000. That's VANESSA to sixty-four thousand. Message and data rates may apply. See terms for details. In this Friday episode, I'm diving into my fascinating conversation with Will Nitze, the founder and CEO of IQBAR—a bar formulated to fuel both the brain and the body. This solocast-style recap explores the unique backstory of how Will built IQBAR from the ground up and how the brand became a leader in the functional protein space. We break down: How Will developed the idea and scaled IQBAR from concept to nationwide success The exact macronutrient profile behind IQBAR and why it's ideal for fat loss The powerful synergy between high protein and high fiber for satiety, stable blood sugar, and body recomposition Why ingredients like MCT oil, lion's mane, magnesium, and omega-3s were included for cognitive support How smart snacking can support fat loss goals—especially when macros are optimized If you're someone who struggles with hitting protein targets on the go, curbing cravings, or simply wants a science-backed, low-carb snack that supports your fat loss journey—this is the episode for you. Learn more about the TONE LUX Crystal red light therapy mask and the accessory the TONE LUX CONTOUR for the neck and décolleté and get 20% OFF with the code VANESSA Free high-protein keto guide: The Keto Reset eBook
IQBAR is offering our special podcast listeners 20% OFF all IQBAR products, plus get FREE shipping. To get your 20% off, text VANESSA to 64000. That's VANESSA to sixty-four thousand. Message and data rates may apply. See terms for details. In today's episode, Vanessa sits down with Dr. Samuel Dicken, Research Fellow at University College London's Centre for Obesity Research and lead author of the UPDATE Trial — the longest and most rigorous clinical study to date comparing ultra-processed (UPF) vs. minimally processed (MPF) diets. This landmark trial revealed a game-changing finding:
Discover how Protein-Sparing Modified Fasting PSMF) Days can unlock rapid fat loss without sacrificing muscle. Vanessa shares her own recent results alongside the latest studies on intermittent high-protein fasting in women. Learn more about the TONE LUX Crystal red light therapy mask and the accessory the TONE LUX CONTOUR for the neck and décolleté and get 20% OFF with the code VANESSA Have you ever wondered if you could accelerate fat loss with just a few high-protein, very low-calorie days each week? In this episode, Vanessa dives deep into the modern science of Protein-Sparing Modified Fasts (PSMF) and how intermittent high-protein fasting can help women lose fat, preserve lean muscle, and improve metabolic health. Vanessa reviews the latest studies on: 1–3 PSMF days per week compared to daily dieting Alternate-day and 5:2 style intermittent fasting approaches with high protein How PSMF days stack up against water fasting and generic low-calorie diets Fat loss, lean mass retention, and insulin sensitivity outcomes in women She also shares her personal PSMF experiment — one month of cycling three PSMF days per week — and reveals her results: fat loss, waist measurement changes, muscle preservation, and how it felt in real life. If you've been curious about modern approaches to PSMF, how to implement them safely, and whether they truly outperform traditional dieting, this episode brings you the evidence and the personal perspective. IQBAR is offering our special podcast listeners 20% OFF all IQBAR products, plus get FREE shipping. To get your 20% off, text VANESSA to 64000. That's VANESSA to sixty-four thousand. Message and data rates may apply. See terms for details. Free high-protein keto guide: The Keto Reset eBook
Send us a textRachel Frase is a returning guest on our show! Be sure to check out her first appearance on episode 767 of Boundless Body Radio, recorded with Dr. Lori Calabrase!Rachel Frase is a practicing registered dietitian in Connecticut with 13 years' experience, who began her career working as a clinical dietitian in the traditional healthcare model, and has spent her last 8 years working with patients to prevent and reverse chronic metabolic conditions.She spent several years in the medical weight loss field, guiding patients with nutritional and lifestyle changes to support and maintain weight loss as well as improve metabolic markers, and the last couple years using tailored ketogenic diets in a metabolic psychiatry practice.Her journey with her own GI issues that could not be resolved by traditional medicine led her down the rabbit holes of diet and lifestyle, as she was determined to get her health and quality of life back. It led her to peel back the layers of what true human nutrition really is and how it heals.She enjoys living an active life and getting outdoors as much as possible. She participates in a variety of activities, currently including running in a club called the Run 169 Towns Society where the goal is to run a race in every town in Connecticut, open water swimming, and hiking with her husband at national park sites.Find Rachel Frase RD-N at-https://www.loricalabresemd.com/http://touchpoints180.org/IG- @rf_nutritionLK- @Rachel Frase RDFind Boundless Body at- myboundlessbody.com Book a session with us here!
IQBAR is offering our special podcast listeners 20% OFF all IQBAR products, plus get FREE shipping. To get your 20% off, text VANESSA to 64000. That's VANESSA to sixty-four thousand. Message and data rates may apply. See terms for details. This episode of the Optimal Protein Podcast takes a deep dive into the Protein-Sparing Modified Fast (PSMF) — a scientifically designed approach for rapid fat loss that prioritizes lean muscle preservation. Listeners will learn: What defines a PSMF and how it works in practice The latest research on fat loss outcomes and muscle retention How PSMF compares with ketogenic diets, VLCDs, and intermittent fasting Differences in results between men and women Short-term benefits and potential challenges with long-term use How to implement cycling strategies, refeed phases, and sustainable maintenance plans Evidence-based guidelines for safe and effective use Packed with research findings and practical insights, this episode provides a clear, evidence-based look at how PSMF can be used as a tool for body recomposition, fat loss, and long-term health. Connect with Vanessa on Instagram @ketogenicgirl Free High-Protein Keto Guide Get 20% off on the Tone LUX Crystal Red Light Therapy Mask or the Tone Device breath ketone analyzer at Ketogenicgirl.com with the code VANESSA Join the Community! Follow Vanessa on Instagram to see her meals, recipes, informative posts, and much more! Click here @ketogenicgirl Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast: The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.
Dr Steven R. Gundry is an American physician and low-carbohydrate diet author, most famous for his book 'Unlocking the Keto Code'. He is also the founder of Gundry MD, dedicated to dramatically improving human health, happiness, and longevity through his unique vision of diet and nutrition. Dr Steven joins Angela to talk about mitochondrial uncoupling, specifically how you can eat certain foods designed to turbo-charge your metabolism, effectively wasting calories, enabling you to support energy and vitality while supporting fat loss at the same time. KEY TAKEAWAYS: Mitochondrial Uncoupling: Mitochondrial uncoupling is a process where the mitochondria waste calories to generate heat, which can enhance metabolism and support fat loss Ketones as Signaling Compounds: Contrary to popular belief, ketones are not a super fuel for the body. Instead, they act as signaling compounds Role of Diet in Longevity: Certain foods, such as spices (e.g., black pepper, cinnamon), fermented cheeses, and beverages like tea and red wine, can enhance mitochondrial uncoupling Impact of Cold and Heat Exposure: Both cold exposure and sauna use can uncouple mitochondria, promoting metabolic health TIMESTAMPS AND KEY TOPICS: [00:00:27] Mitochondrial uncoupling explained. [00:05:39] Ketogenic diet for seizure reduction. [00:19:24] Insulin and fat storage. [00:29:04] Cost-of-living hypothesis and aging. [00:49:45] Melatonin in the Mediterranean diet. [00:53:38] Sauna and cold exposure benefits. [00:56:47] Red light therapy benefits. VALUABLE RESOURCES Get a free snapshot of your health and personalised report at www.yourtotalhealthcheck.com Join The High Performance Health Community Click here for discounts on all the products I personally use and recommend A BIG thank you to our sponsors who make the show possible: Sign Up to Angela's Weekly Fresh Starts Email to transform your health, energy, and longevity with just ONE small habit every week - angelafoster.me/freshstart Check out Defender Shield's products and save 10% with code ANGELA at http://defendershield.com/angela Get 20% off the Creatine I love at http://trycreate.co/ANGELA20 and use code ANGELA20 to save 20% on your firsts order. ABOUT THE HOST Angela Foster is an award winning Nutritionist, Health & Performance Coach, Speaker and Host of the High Performance Health podcast. A former Corporate lawyer turned industry leader in biohacking and health optimisation for women, Angela has been featured in various media including Huff Post, Runners world, The Health Optimisation Summit, BrainTap, The Women's Biohacking Conference, Livestrong & Natural Health Magazine. Angela is the creator of BioSyncing®️ a blueprint for ambitious entrepreneurial women to biohack their health so they can 10X how they show up in their business and their family without burning out. CONTACT DETAILS Instagram Facebook LinkedIn Disclaimer: The High Performance Health Podcast is for general information purposes only and do not constitute the practice of professional or coaching advice and no client relationship is formed. The use of information on this podcast, or materials linked from this podcast is at the user's own risk. The content of this podcast is not intended to be a substitute for medical or other professional advice, diagnosis, or treatment. Users should seek the assistance of their medical doctor or other health care professional for before taking any steps to implement any of the items discussed in this podcast. This Podcast has been brought to you by Disruptive Media. https://disruptivemedia.co.uk/
IQBAR is offering our special podcast listeners 20% OFF all IQBAR products, plus get FREE shipping. To get your 20% off, text VANESSA to 64000. That's VANESSA to sixty-four thousand. Message and data rates may apply. See terms for details. Today's episode is a deep-dive recap of my mind-blowing conversation with Dr. Paul Laursen — one of the world's top experts in exercise physiology, high-intensity interval training (HIIT), and fat-adapted performance. If you've ever wondered: Why you feel better fat-fueled than carb-loaded How diet actually drives fat loss more than training Why ketones might be more than a fuel — and actually a proxy for VO₂ max How to optimize your metabolic flexibility using HIIT and protein-forward nutrition …this episode will change how you see your body composition journey — especially if you've been trying to out-exercise a poor diet.
Nicole Laurent, MA, LMHC, is a licensed mental health counselor, nonprofit founder of Brain Fog Recovery Source, and clinical innovator in metabolic psychiatry. Nicole specializes in the targeted use of ketogenic metabolic therapy (KMT) to achieve remission in psychiatric disorders traditionally labeled treatment resistant. Through her clinical practice, peer reviewed articles, educational blog, continuing education programs for psychotherapy professionals, and nonprofit initiatives, Nicole challenges conventional psychiatric paradigms and increases access to evidence based ketogenic interventions for low income and government disabled populations globally. She reframes how mental health clinicians conceptualize and implement treatments, moving the field toward genuine remission and improved patient outcomes. Timestamps: 00:00 Trailer 00:31 Introduction 06:15 Nutrition's role in chronic disease 10:25 Effect of supportive guidance on health outcomes 14:00 Challenges of deprescribing medications 17:13 Transdiagnostic mental health intervention 20:14 Ketogenic diet in metabolic psychiatry 22:49 Dietary consultation 27:47 Psychotherapy and ethics 29:48 Metabolic psychiatry's growing influence 32:22 Nonprofit expands treatment access 38:27 Personal experience fuels advocacy 41:22 Inpatient support for mental illness 44:17 Where to find Nicole Instagram: https://www.instagram.com/mentalhealthketo/ X: https://x.com/KetoCounselor YouTube: https://www.youtube.com/@nicolelaurentLMHC Other: https://mentalhealthketo.com/brain-fog-recovery-source-501c3/ Website: https://www.every.org/brain-fog-recovery-source/f/metabolic-psychiatric Join Revero now to regain your health: https://revero.com/YT Revero.com is an online medical clinic for treating chronic diseases with this root-cause approach of nutrition therapy. You can get access to medical providers, personalized nutrition therapy, biomarker tracking, lab testing, ongoing clinical care, and daily coaching. You will also learn everything you need with educational videos, hundreds of recipes, and articles to make this easy for you. Join the Revero team (medical providers, etc): https://revero.com/jobs #Revero #ReveroHealth #shawnbaker #Carnivorediet #MeatHeals #AnimalBased #ZeroCarb #DietCoach #FatAdapted #Carnivore #sugarfree Disclaimer: The content on this channel is not medical advice. Please consult your healthcare provider.
Send us a textGregg Rocheford became a personal friend as we met through our show! Gregg worked as a geologist, an IT professional, and has climbed Devils Tower, jumped out of a plane (twice), and slept in a snow cave!In 2021, Gregg heard that an approach called “intermittent fasting” was effective for losing weight. As a chair bound IT professional, Gregg developed a soft muffin top around his waistline.In August 2021, Gregg fasted for 206 hours in three weeks and started a physical Therapy program for past shoulder injuries. He began to notice big changes, and even his wife was impressed with the changes she had noticed in such a short time. He then began eating a low carbohydrate, meat-based diet which produced even more results.After retiring at 62, in 2022, Gregg purchased a college biology textbook at his local Goodwill. What followed is a continuing and amazing journey of body and mind. Gregg joined a local YMCA when he turned 65 in 2024 and has added enough muscle mass that he gets regular compliments from many who guess that he is much younger than 65. Recently, he began a part-time job at the YMCA as a Health and Wellness Coach!Find Gregg at-FB- @Gregg RochefordAnd stay tuned!Find Boundless Body at- myboundlessbody.com Book a session with us here!
IQBAR is offering our special podcast listeners 20% OFF all IQBAR products, plus get FREE shipping. To get your 20% off, text VANESSA to 64000. That's VANESSA to sixty-four thousand. Message and data rates may apply. See terms for details. Today's guest is Dr. Paul Laursen — exercise physiologist, endurance coach, co-author of HIIT Science: The Science and Application of High-Intensity Interval Training, and co-founder of Athletica.ai. Dr. Laursen has coached athletes to 17 world championships, and his research on HIIT, metabolic flexibility, and low-carb nutrition has shaped how athletes and everyday people train for health and performance. In this episode, we cover: Why diet—not exercise—is the key driver of fat loss (and the clinical study that proved it) How being fat-fueled is actually a proxy for VO₂ max, a key marker of cardiovascular fitness and longevity The difference between burning carbs vs. burning fat during exercise — and why metabolic flexibility matters for performance and health How to use HIIT protocols strategically for fat loss, insulin sensitivity, and body recomposition without overtraining Why low-carb and very low-carb high-fat diets can supercharge fat oxidation, recovery, and cognitive clarity The role of ketones in appetite control, recovery, and brain performance Dr. Laursen's top recommendations for training, nutrition, and recovery to optimize body composition and metabolic health Whether you're an athlete, a weekend warrior, or someone looking to improve body composition and metabolic resilience, this conversation is packed with actionable strategies to help you get leaner, stronger, and more metabolically fit. Connect with Vanessa on Instagram @ketogenicgirl Free High-Protein Keto Guide Get 20% off on the Tone LUX Crystal Red Light Therapy Mask or the Tone Device breath ketone analyzer at Ketogenicgirl.com with the code VANESSA Join the Community! Follow Vanessa on Instagram to see her meals, recipes, informative posts, and much more! Click here @ketogenicgirl Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast: The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.
IQBAR is offering our special podcast listeners 20% OFF all IQBAR products, plus get FREE shipping. To get your 20% off, text VANESSA to 64000. That's VANESSA to sixty-four thousand. Message and data rates may apply. See terms for details. In this Part 2 solo recap episode, Vanessa Spina continues breaking down her powerful conversation with protein pioneer Dr. Donald Layman—covering the second half of their in-depth interview on metabolism, insulin resistance, muscle maintenance during menopause, and the launch of a groundbreaking new Protein Quality Hub. If you've ever wondered how to structure your meals to maximize fat loss, support lean mass, and protect your metabolic health as you age—this is the episode you've been waiting for.
Dr. Tro Kalayjian is a board-certified physician in Internal Medicine and Obesity Medicine, and the founder of Toward Health, a virtual metabolic health clinic helping people break free from food addiction and chronic metabolic disease. He's also a founding member of the Society of Metabolic Health Practitioners and an international speaker on metabolic psychiatry, obesity, and nutrition science. But what makes Dr. Tro's work truly powerful is that it's personal. He grew up in a household affected by obesity and struggled with his own weight into adulthood, reaching over 350 pounds. After years of frustration with traditional medical advice, he took a deep dive into the research and completely transformed his health—losing over 150 pounds and sustaining that loss for more than a decade. His clinic's latest research, published in Frontiers in Psychiatry, shows how combining low-carb nutrition with real-time support, psychological care, and metabolic monitoring can significantly reduce food addiction and binge eating symptoms—offering hope for those who haven't found relief in diets or medications alone. Dr. Tro is passionate about helping others find food freedom, and today he's here to share the science, the struggle, and the solutions that actually work. Research Highlights: Published in Frontiers in Psychiatry (2025): 43 lbs average weight loss ~40–50% improvement in food addiction and binge eating symptoms Outcomes comparable to medications (e.g. amphetamines, GLP-1s) — but without long-term side effects Case series (220 people) on keto for binge eating showed significant improvements, challenging the old myth that "restrictive diets worsen eating disorders"
Unlock sharper focus and support long-term brain health with Ketone-IQ—clean brain fuel for deep work, mental clarity, and sustained energy with no crash. Get 30% off your subscription, plus a free gift with your second shipment at Ketone.com/vanessa. In Part 2 of this powerful interview, legendary protein researcher Dr. Donald Layman returns to the Optimal Protein Podcast to unpack some of the most misunderstood concepts in nutrition today—and to reveal potential groundbreaking changes to the U.S. dietary guidelines around protein, red meat, saturated fat, and carbohydrates. Dr. Layman breaks down what the science actually says about protein dosing, timing, oxidation, and muscle uptake—and who truly needs to worry about protein distribution. Vanessa and Dr. Layman also discuss:
IQBAR is offering our special podcast listeners 20% OFF all IQBAR products, plus get FREE shipping. To get your 20% off, text VANESSA to 64000. That's VANESSA to sixty-four thousand. Message and data rates may apply. See terms for details. In this Friday solo episode, Vanessa Spina breaks down the first half of her latest interview with Dr. Donald Layman — legendary protein researcher and one of the most featured guests in the history of the Optimal Protein Podcast. They cover game-changing updates to U.S. dietary guidelines, red meat's misunderstood role in metabolic health, and the science of protein timing for fat loss and body recomposition. Whether you're over 30, in a fat loss phase, or simply looking to optimize your protein intake, this episode is packed with insight.
Unlock sharper focus and support long-term brain health with Ketone-IQ—clean brain fuel for deep work, mental clarity, and sustained energy with no crash. Get 30% off your subscription, plus a free gift with your second shipment at Ketone.com/vanessa. This week on the Optimal Protein Podcast, I'm thrilled to be joined once again by Dr. Don Layman, one of the world's foremost experts in protein metabolism and amino acid science. In this first part of our two-part conversation, we take a deep dive into the true definition of protein quality, the flaws of current scoring systems, and the metabolic significance of leucine as a primary trigger for muscle protein synthesis. Dr. Layman also introduces the EAA-9 protein quality model, a new way of evaluating protein sources that takes into account the body's exact essential amino acid requirements—moving beyond methods like PDCAAS. Get 20% off on the Tone LUX Crystal Red Light Therapy Mask Ketogenicgirl.com with the code VANESSA We also discuss: Why protein quality should be defined by amino acid content, not nitrogen How leucine “shows up in nature” in exact ratios that muscle recognizes The four key signals muscle responds to: energy, leucine, insulin, and IGF-1 What activates and suppresses mTOR, and why AMPK shuts down MPS in low energy states How protein turnover drives up to 20% of your resting metabolic rate The concept of metabolic prioritization and what happens when your diet lacks adequate EAAs Why the term “protein requirement” is misleading—and why we actually have amino acid requirements Dr. Layman's response to the 100 g of protein study on protein distribution A preview of what's really happening during fat loss, and how muscle preservation strategies can make or break long-term success This episode is a masterclass in muscle metabolism, protein science, and the tools you need to optimize your nutrition—especially for fat loss and body recomposition.