Podcasts about ketogenic

Send us Fan MailChris DeLisle of Chris Cooking Nashville is Nashville's own Primal Pioneer, whose personal carnivore transformation led to over 100 pounds of weight loss, shatters diet dogma and hands you the ultimate chef's setlist for bold, unapologetic meat-focused cooking.Inside his new book Eat Your Meat, Love Your Life: Rock and Roll Carnivore Cooking to Crank Your Kitchen to 11, you'll find the following-130 knockout recipes, from no‑nonsense beginner fare like Fire and Fat Beef Patties with Brie and Poppin' Pork Chops with a Mustard Sear, to advanced showstoppers like Roadie Meatloaf with Pepper Jack Stuffing and Crack of Noon Cured Salmon with Caper Sour Cream;A progressive skill‑building structure that transforms you from meat‑minded novice to kitchen commander;Rock‑and‑roll callouts and punch‑in‑your-gut quotes to keep you fired up between chapters;And Real‑world meal plans, grocery lists, and prep strategies to supercharge your results!Whether you're battling brain fog, stalling on the scale, or craving a lifestyle that ignites every cell in your body, this book is your ticket to primal power. It's time to silence the sugar sirens, ditch the carb crutches, and fuel your body with the most ancient—and effective—fuel on the planet.Ready to roar? Crack open Eat Your Meat, Love Your Life and take the first bite toward a stronger, sharper, more powerful you on a rock-and-roll tour of culinary creation!Find Chris at-https://www.chriscookingnashville.com/Book- Eat Your Meat, Love Your Life: Rock and Roll Carnivore Cooking to Crank Your Kitchen to 11YT- Chris Cooking NashvilleAsh and Chris' Music- https://www.ashtaylor.com/Find Boundless Body at-myboundlessbody.comBook a session with us here! 

Can ketogenic therapy be safe for someone with heart disease, atherosclerosis, or a stent? Can you follow a ketogenic diet without losing weight? In this Metabolic Mailbag episode, Dr. Bret Scher answers viewer questions about ketogenic therapy, cardiovascular risk, anorexia recovery, pregnancy and nursing, schizophrenia remission, keto on a budget, and whether doctors learn about ketogenic therapy in medical school.He covers:Ketogenic therapy and cardiovascular disease after a stent or atherosclerosisHow to follow a ketogenic diet without unwanted weight lossWhat early research suggests about ketogenic therapy for weight-restored anorexiaKetogenic therapy during pregnancy or nursing, and why clinical supervision is essentialLab markers that may change during sustained nutritional ketosisWhy schizophrenia symptom remission is different from a cureHow genetics and metabolism may both contribute to serious mental illnessBudget-friendly ways to approach a well-formulated ketogenic dietWhy keto is rarely taught in medical schoolThe big takeaway is that ketogenic therapy is best understood as a clinical tool, not a one-size-fits-all template. Heart history, weight goals, symptoms, labs, pregnancy, medications, budget, and support all shape what the right approach looks like.

Send us Fan MailToday we're releasing a new episode from a brand new series called the Boundless Body Radio Heritage Series! I wanted to do something extra special to celebrate 1,000 podcast episodes recorded here at Boundless Body Radio, a milestone that we hit on June 24, 2026!These episodes are actually not new, although they might be new to you! When we first got started back in October, 2020, I was so fortunate that so many incredible people said "YES" to being hosted on the show, however, we didn't have very many listeners at the time!Today, we get thousands of downloads every single month, and are usually included in the top 150 Fitness and Nutrition Podcasts on the Apple Podcast charts!To honor our amazing guests, I will be selecting one of those original episodes and posting them here on for this special series!As I was going through these episodes again, I remembered how valuable these conversations actually were. it was really striking how much the information these experts have shared has born out to be even more accurate several years later.The audio quality of a show was not as good back then as it is now, but I still really hope you enjoy these episodes, and find them relevant and helpful to you today!Cheers, thanks as always for listening, and I really hope you enjoy this episode of the Boundless Body Radio Heritage Series!Dr. Thomas Seyfried is a returning guest on our show! Be sure to check out his first appearance on Boundless Body Radio on episode 60, which one of the most fascinating discussions we've ever had, all about cancer as a metabolic disease! He was also hosted on episode 363 of our podcast.Thomas N. Seyfried received his Ph.D. in Genetics and Biochemistry from the University of Illinois, Urbana, in 1976. He was a Postdoctoral Fellow in the Department of Neurology at the Yale University School of Medicine and then served on the faculty as an Assistant Professor in Neurology. Other awards and honors have come from such diverse organizations as the American Oil Chemists Society, the National Institutes of Health, The American Society for Neurochemistry, the Ketogenic Diet Special Interest Group of the American Epilepsy Society, the Academy of Comprehensive and Complementary Medicine, and the American College of Nutrition.Dr. Seyfried has over 150 peer-reviewed publications and is the author of the book, Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer (Wiley, 1st ed., 2012).Find Dr. Seyfried at-https://foundationformetaboliccancertherapies.com/Movie, coming soon- CANCERREVOLUTION: A Cancer Science Documentary with Dr. Seyfried and former podcast guest Travis Christofferson.Find Boundless Body at-myboundlessbody.comFind Boundless Body at-myboundlessbody.comBook a session with us here! 

Dr Anthony Chaffee joins Trending with Timmerie. His work focuses on metabolic health and healing from chronic disease. Episode Guide Recovering from cancer with carnivore (1:11) Healing low testosterone (22:33) Prostate cancer and testosterone blockers (32:43) Anxiety post menopause (35:29) Why is there a birth rate crisis in the US? What can we do about it? (40:22) Do we believe in women’s empowerment? (47:21) Resources mentioned: Dr. Anthony Chaffee https://www.dranthonychaffee.com/ Harvard study on Carnivore/Ketosis and depression https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2022.951376/full https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-024-03775-4 Otto Warburg, on the origin of cancer cells https://www.science.org/doi/abs/10.1126/science.123.3191.309 Cancer Treatment With the Ketogenic Diet: A Systematic Review and Meta-analysis of Animal Studies https://www.frontiersin.org/articles/10.3389/fnut.2021.594408/full Ketogenic diets and cancer treatment https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375425/ UW review of over 800 studies in the literature: weak to no evidence for meat and cancer risk or any other disease, and especially not unprocessed red meat https://www.nature.com/articles/s41591-022-01968-z Keto Mojo https://shop.keto-mojo.com Fatal Tesla Crash Into Texas Home Now Under Federal Safety Investigation https://www.wsj.com/business/autos/fatal-tesla-crash-into-texas-home-now-under-federal-safety-investigation-48cfeebe Dr. Caldwell episode https://relevantradio.com/2025/10/how-your-gut-mind-and-birth-control-are-connected/ Past Dr. Chaffee Episode https://relevantradio.com/2025/07/adhd-autism-carnivore-2/

Send us Fan MailDr. Jocelyn Foran is a Canadian medical doctor and Staff Anesthesiologist at Nova Scotia Health Authority, holding a Fellowship from the Royal College of Physicians and Surgeons of Canada (FRCPC) and a Diplomat of the American Board of Obesity Medicine.Through her private practice, Upstream Metabolic Medical, she promotes ketogenic and carnivore diets as treatments for chronic disease and metabolic conditions — dietary approaches that remain contested within mainstream nutrition science and are not endorsed by major public health bodies.While her clinical background is in anesthesiology rather than nutrition or dietetics, she has pursued additional training as a Metabolic Health Practitioner through the Nutrition Network, an organization that advocates low-carbohydrate diets.Metabolism is the process of turning food into form and function- yes, we ARE what we eat. Our metabolism is the core to our health, balancing everyday building (anabolism) with the breakdown of cells (catabolism). In our 21st-century toxic food environment, many of us are now living with metabolic dysfunction and chronic diseases that result: high blood pressure, obesity, insulin resistance, diabetes, infertility, autoimmune illnesses, mental illnesses and cancer. These chronic diseases are not cured, but rather “managed” with medications, often for the rest of our lives.Metabolic coaching focuses on root cause healing to address and reverse chronic illnesses, empowering patients to improve their health by addressing lifestyle issues.Find Dr. Jocelyn Foran at-https://www.metabolicmedical.ca/aboutIG- @MetabolicMedicalFB- @Metabolic MedicalFind Boundless Body at-myboundlessbody.comBook a session with us here! 

Kristina became passionate about metabolic therapies and the power of nutrition as both prevention and treatment for chronic illnesses and psychiatric conditions after witnessing her daughter achieve rapid remission from bipolar disorder through a whole foods ketogenic and then carnivore diet. Her family's remarkable health transformation using food as medicine inspired her to pursue further education in nutrition and metabolic health. As a dedicated advocate for these life-changing therapies, Kristina is committed to raising awareness, expanding access, and empowering others to take charge of their physical and mental well-being through dietary and lifestyle strategies. Socials: Instagram:  https://www.instagram.com/thebetterhumansproject?igsh=OTZldmwwaG1tMGg%3D&utm_source=qr Facebook:  https://www.facebook.com/groups/1401476164164301/?ref=share&mibextid=wwXIfr&rdid=8bpynYy9YxXtzqAG&share_url=https%3A%2F%2Fwww.facebook.com%2Fshare%2Fg%2F18DkW7E5Aj%2F%3Fmibextid%3DwwXIfr# Timestamps: 00:00 Trailer 00:48 Introduction 03:27 Managing daughter's emotional challenges 06:22 Discussing childhood obesity factors 10:19 Addressing infant indigestion issues 13:27 Getting a new family doctor 18:18 Switching to local fresh food 21:19 Discovering the impact of eating well 23:08 Life-changing improvements in mental health 29:13 Trust in healthcare post-COVID 31:58 Transitioning to a carnivore diet 36:40 Health concerns and government response 40:09 Importance of nutrition in health 42:30 Personal transformation and community support 45:33 Addressing chronic disease with support 47:32 Social media and Better Humans Project Join Revero now to regain your health: https://revero.com/YT Revero.com is an online medical clinic for treating chronic diseases with this root-cause approach of nutrition therapy. You can get access to medical providers, personalized nutrition therapy, biomarker tracking, lab testing, ongoing clinical care, and daily coaching. You will also learn everything you need with educational videos, hundreds of recipes, and articles to make this easy for you. Join the Revero team (medical providers, etc): https://revero.com/jobs ‪#Revero #ReveroHealth #shawnbaker  #Carnivorediet #MeatHeals #AnimalBased #ZeroCarb #DietCoach  #FatAdapted #Carnivore #sugarfree Disclaimer: The content on this channel is not medical advice. Please consult your healthcare provider.

Ketogenic and low-carbohydrate diets often focus on a specific carbohydrate target: keep your net carbs under 30 grams. But as registered dietitian and certified diabetes educator Franziska Spritzler demonstrates in this presentation from Metabolic Health Summit, a carbohydrate target is not a therapy. Effective implementation means a full assessment of medical history, medications, labs, food preferences, lifestyle, and the motivation that will carry a patient through year one and beyond.Spritzler specializes in low-carbohydrate and ketogenic nutrition and has extensive experience helping people use these approaches to improve metabolic health. The creator of lowcarbdietitian.com, she walks through the practical decisions clinicians face: when a ketogenic diet is warranted versus a more flexible low-carbohydrate approach, why she recommends 1.2 to 1.8 grams of protein per kilogram rather than the RDA's 0.8, how to manage medication adjustments for patients at risk of hypoglycemia or hypotension, and how to handle electrolytes, carbohydrate counting, sweeteners, and plant-based variations without losing the patient along the way.Questions Answered in This Episode:• What actually separates a ketogenic diet from a low-carbohydrate diet, and when does the difference matter?• Why is the protein RDA too low for long-term metabolic health, and what range does Spritzler recommend instead?• Who should avoid ketogenic diets entirely, and why are most contraindications manageable with closer supervision?• How should medications be monitored and adjusted when a patient begins carbohydrate restriction?• Should patients count net carbs or total carbs, and why are packaged "net carb" labels unreliable?• Can a ketogenic diet be done as a vegetarian or vegan?A practice-tested blueprint for turning carbohydrate restriction from a prescription into a therapy patients can sustain.Special thanks to the sponsors of this episode:✅ Genova Connect: Get 15% off any Genova Connect test kit with code METABOLICLINK here.✅ iRestore: Get a special discount on the iRestore Illumina Face Mask with code LINK here.✅ fatty15: Get an additional 50% off a 90-day subscription starter kit with code METABOLICLINK.✅ Zocdoc: Find and instantly book a top-rated doctor here.More Links• Franziska's website: lowcarbdietitian.com• The Metabolic Initiative (expert lectures, CME, ad-free episodes, live Q&As; first 7 days free): membership.metabolicinitiative.comIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: InstagramFacebookYouTubeLinkedInPlease keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Could metabolic therapies become part of the future of cancer care?That question sits at the center of Dr. Bret Scher's conversation with neurologist and researcher Dr. Matthew Phillips, whose recent study explored a metabolic approach in people with glioblastoma, one of the most aggressive forms of brain cancer.Rather than relying on a single intervention, the study combined a ketogenic diet, intermittent fasting, and repeated five-day fasts alongside standard chemotherapy and radiation. Together, these strategies were designed to lower the Glucose Ketone Index, or GKI, by reducing glucose and increasing ketones.In this conversation, they explore:Why cancer cell metabolism is becoming an important area of researchHow glucose, ketones, and mitochondrial function may influence cancer growthWhy the GKI was a central target in the studyHow fasting and ketogenic therapy were integrated with standard cancer treatmentThe difference between intentional weight loss and cancer cachexiaWhy quality of life deserves as much attention as survivalWhat the study's long-term survivors may teach researchersWhy larger randomized trials are still neededParticipants following the metabolic protocol achieved an average GKI of 1.88, and every participant completed all eight five-day fasts. The metabolic therapy group also had a median survival of 21 months compared with 14 months in the control group, along with a higher rate of survival beyond three years.These results offer a compelling reason to keep studying this approach, particularly in a cancer with such limited treatment options and a difficult prognosis. Since the trial was small and nonrandomized, it can't provide definitive answers, but it does give researchers a strong foundation to build on.

Send us Fan MailPatrick Coles, Ph.D., is the Chief Scientist at Normal Computing, where he develops novel computing hardware for Artificial Intelligence (AI) applications. Previously, he was a Staff Scientist at Los Alamos National Lab (LANL), where he made important contributions to the theory of quantum computing.Patrick has a broad background, having done his PhD in Chemical Engineering at Berkeley and his MPhil in Biochemistry at Cambridge. Currently, Patrick is working on a new theory for cancer and chronic disease. His Toxin Sequestration Theory (TST) of cancer was featured on the cover of the Masters Of Health magazine.He regularly discusses TST in his Substack blogs and his YouTube channel. He is also passionate about the carnivore diet, which he's been doing for 19 months now.Find Patrick at-YT- @OxalateWarriorSubstack- @patrickcolesTW- @ColesThermoAIFind Boundless Body at-myboundlessbody.comBook a session with us here! 

How many grams of protein do you need to be healthy? What about fiber? Supplements? It feels like we're changing our diets daily to adhere to constantly shifting recommendations and none of it is really working to optimize our health. Christopher Gardner, Professor of Medicine in Nutrition Science at Stanford University, and featured advisor on the Netflix show, “You Are What You Eat: A Twin Experiment”, joins us today to talk about how the industry is stacked against us and why the solution to our diet woes is as simple as beans, peas, and lentils. For more than 30 years Christopher Gardner, PhD, has studied what to consume and to avoid for optimal health, and how best to motivate individuals to achieve healthy dietary behaviors. He recently completed a two-year term serving on the US Dietary Guidelines Advisory Committee and is the past chair of the American Heart Association's Nutrition Committee. He has conducted and published dozens of human nutrition intervention trials, including trials of Mediterranean, Ketogenic, Vegan, Low-Fat and Low-Carb diets and their effects on cardiometabolic health. Some of his current interests include Stealth Nutrition, Unapologetic Deliciousness and Institutional Food Settings. He is currently working on personalized nutrition explorations with several colleagues, with particular focus on the gut microbiome.

Send us Fan MailNicolas Hunter is an experienced extended faster who has transformed his health through a combination of fasting, carnivore-based nutrition, and nutrient-dense ancestral foods.After reaching more than 345 pounds, Nicolas lost over 185 pounds and gradually moved away from calorie counting, constant restriction, and the idea that eating less every day was the answer. Today, he uses carnivore not as a rigid ideology, but as a practical metabolic tool that makes extended fasting feel natural and sustainable.His current rhythm often consists of a 72-hour fast, followed by two generous one-meal-a-day refeed days, and then another 72-hour fast. When he eats, he prioritizes meat, fish, eggs, traditional dairy, and other simple, nourishing foods, eating until genuinely satisfied rather than counting calories. Nicolas believes fasting should not feel like punishment, starvation, or a daily battle against hunger. For him, the real breakthrough came when food stopped controlling his attention and the constant “food noise” disappeared.Nicolas no longer sees fasting as endlessly deciding not to eat. He sees it as regaining the freedom to decide when to eat. His philosophy is simple: fasting is not something you force through suffering—it is a natural state the body can return to when it is properly nourished. Carnivore is the tool, extended fasting is the practice, and freedom from constant hunger is the result.Nick's motto is- "Fasting is not when you spend your life deciding not to eat. Fasting begins when you regain the freedom to decide when to eat."Find Nicolas at-Email- nickhuntersf@me.comFind Boundless Body at-myboundlessbody.comBook a session with us here! 

In this episode we dive into the metabolic and lifestyle foundations that drive chronic fatigue, ME/CFS, and energy dysfunction. Blood sugar stabilization is covered in depth, from managing hypoglycemia and insulin resistance to the role of ketogenic nutrition in difficult cases that have not responded to other approaches. We also look at hydration and electrolyte balance as an underappreciated piece of cellular energy production, and walk through practical sleep strategies including weighted blankets, white noise, mouth taping, and building a consistent sleep routine. Register for Chronic Fatigue and Pain Syndromes Clinical Strategies and Treatment Applications at https://pages.kharrazianinstitute.com/chronic-fatigue-and-pain-syndromesTo become a Certified Functional Medicine practitioner, visit https://kharrazianinstitute.com/⁠. Try our 7-day free trial, no credit card required. TIMESTAMPS: 00:00 Discussing blood sugar and energy levels06:17 Ketogenic diet benefits for ME/CFS10:16 Getting started with intermittent fasting12:01 Intermittent fasting and autophagy benefits15:40 Hydration and fatigue management tips18:58 Addressing sleep hygiene basics23:14 Benefits of weighted blankets and calming aids27:14 Improving sleep for chronic fatigue30:00 Promoting educational health resourcesSupport this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

Send us Fan MailChristine Horton, CHC, RDH, FAAOSH, FADHA, CH-OSE is a dental hygenest, and a health coach specializing in PMOS (Polyendocrine  Metabolic Ovarian Syndrome) and PCOS (Polycystic Ovary Syndrome). She is the founder of Fusion Health Coaching, and the Programs & Advocacy Co-Director of the PCOS Awareness Association.Christine is passionate about helping women with PMOS | PCOS feel truly heard, connecting medical, dental, and lifestyle health to find the answers standard care leaves out. Christine Horton lives with PMOS | PCOS and helps other women bridge the gaps between their medical, dental, and lifestyle health, the connection standard PCOS care routinely overlooks.As the founder of Fusion Health Coaching and creator of The Fusion PATHWAY, she also serves as Programs & Advocacy Co-Director for the PCOS Awareness Association. Based in Greater Houston, Christine meets women where they are- listening first, then walking beside them as they figure it out.Find Christine at- https://fusionhealthcoach.com/LK- Christine Hortonhttps://www.pcosaa.org/Find Boundless Body at-myboundlessbody.comBook a session with us here! 

Dr Anthony Chaffee joins Trending with Timmerie. His work focuses toward metabolic health and healing from chronic disease. Episode Guide Recovering from cancer with carnivore (0:56) Healing low testosterone (22:03) Prostate cancer and testosterone blockers (32:42) Anxiety post menopause (35:29) Pro-life training camp for teenagers (41:00) Tomorrow on Trending (50:57) Resources mentioned: Register for Vox Vitae with $100 off discount code: Timmerie100 https://www.voxvitae.org/camps Dr. Anthony Chaffee https://www.dranthonychaffee.com/ Harvard study on Carnivore/Ketosis and depression https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2022.951376/full Share the flyer for Vox Vitae https://www.facebook.com/photo/?fbid=1445123434310121&set=a.548611617294645 https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-024-03775-4 Otto Warburg, on the origin of cancer cells https://www.science.org/doi/abs/10.1126/science.123.3191.309 Cancer Treatment With the Ketogenic Diet: A Systematic Review and Meta-analysis of Animal Studies https://www.frontiersin.org/articles/10.3389/fnut.2021.594408/full Ketogenic diets and cancer treatment https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375425/ UW review of over 800 hundred studies in the literature: weak to no evidence for meat and cancer risk or any other disease, and especially not unprocessed red meat https://www.nature.com/articles/s41591-022-01968-z Keto Mojo https://shop.keto-mojo.com Fatal Tesla Crash Into Texas Home Now Under Federal Safety Investigation https://www.wsj.com/business/autos/fatal-tesla-crash-into-texas-home-now-under-federal-safety-investigation-48cfeebe Dr. Caldwell episode https://relevantradio.com/2025/10/how-your-gut-mind-and-birth-control-are-connected/ Past Dr. Chaffee Episode https://relevantradio.com/2025/07/adhd-autism-carnivore-2/

Can ketogenic therapy help atrial fibrillation? What should you make of the KETO-CTA study? And do higher ketones always mean better results?In this Metabolic Mailbag episode, Dr. Bret Scher answers audience questions about cardiovascular health, ketosis, ketone levels, and how to personalize a ketogenic approach based on your goals and metabolic health. From AFib concerns to cholesterol controversies and troubleshooting low ketone readings, this episode tackles some of the most common questions in the keto community.In this episode, we cover:Ketogenic therapy and atrial fibrillation (AFib)The latest update on the KETO-CTA studyLDL cholesterol, plaque, and cardiovascular riskWhy ketone levels don't tell the whole storyRaising ketones without sacrificing energy or muscleCarbohydrate intake and metabolic flexibilityFasting, protein, and thyroid considerationsMCT oil, exogenous ketones, and other strategies to increase ketosisOne of the biggest takeaways: context matters. Whether you're evaluating cholesterol, ketone levels, or cardiovascular risk, there is rarely a one-size-fits-all answer. Understanding your goals, metabolic health, and individual response is often more important than chasing a specific number.

Send us Fan MailDr. Austin Dudzinski is a Clinical Pharmacist at Think Whole Person Healthcare, and enjoys working with cardiometabolic disorders, especially diabetes and dyslipidemia.Think Whole Person Healthcare partners with physicians in many areas of care, keeping primary care, specialists, and diagnostics all under the same roof, saving their patients time, emotional effort, and money.What Dr. Dudzinsky finds most exciting about working in Medicine is that there are always innovations on the horizon, especially in preventive medicine for diseases such as cancer and dementia. He has known he's wanted to work in this field since college.What Dr. Dudzinski loves most about working at think is that it provides him with the opportunity to use the entire body of knowledge that he has learned and apply it to help patients. If asked, he thinks his patients would say he's, “The bald pharmacist that calls them about their diabetes.”When he's not at work, he enjoys playing guitar, exercising, reading medical literature, and hanging out with his wife and son.Find Dr. Dudzinsky at-TW/X- @ApoDudzhttps://thinkhealthcare.org/Find Boundless Body at-myboundlessbody.comBook a session with us here! 

Send us Fan MailDr. Jodi Nishida is a returning guest on our show! Be sure to check out her first appearance on episode 721 of Boundless Body Radio!Dr. Jodi Nishida is a Doctor of Pharmacy and accredited Metabolic Healthcare Practitioner who has been in healthcare for over 30 years. After experiencing the ketogenic lifestyle's effect on her own autoimmune condition, she decided to build a keto-based medical practice called The Keto Prescription so others could benefit from it too.Over the last several years, she has helped thousands of patients realize the benefits of clean, medically guided keto. With an accreditation in ketogenic nutrition; certifications in cardiovascular disease management, pharmacogenomics, and medication management; and first-hand experience working in gastrointestinal clinics and women's health clinics, Jodi works closely with each patient to tailor keto to their medications, medical conditions, lifestyle, and socioeconomic situation.Health is not a one-size-fits-all approach, and we all have unique challenges. Because all of us are addicted to sugar and processed food to some extent, fueled largely by our food industry, she has also partnered with two highly qualified psychologists locally, to help her patients address the root of their eating behaviors.She is also the owner of her latest venture, Rise Cafe, located in Honolulu, HI! The coffee shop is an offshoot of her medical practice where she can proudly bring low carb, no sugar items to the people of Hawaii. Rise Cafe is their combined effort to improve the health of those who visit!Find Dr. Jodi Nishida at-https://weloverise.com/IG- @theketoprescriptionhttps://www.theketoprescription.com/Check out the HILAROUS reviews on Yelp!Find Boundless Body at-myboundlessbody.comBook a session with us here! 

Today we have Dr. Dominic D'Agostino, who over the past 10 years has been a frequent guest on STEM-Talk. Today Dom joins us to give us an update on his recent research into ketogenic metabolic therapies, ketone supplements as well as hyperbaric oxygen therapy for traumatic brain injuries. Dom and his lab at the University of South Florida have published more than 20 papers since his last appearance on STEM-Talk in 2023. Dom is an Associate Professor in the Department of Molecular Pharmacology and Physiology at South Florida's Morsani College of Medicine. Dom has a background in neuroscience, molecular pharmacology, nutrition and physiology. In addition to developing and testing metabolic-based therapies, Dom's lab also investigates seizure disorders, brain cancer, neurodegenerative diseases and rare genetic-metabolic disorders. Show notes: [00:03:28] Dawn welcomes Dom back to the show and explaining that he has been quite busy since his last appearance, authoring or co-authoring more than 20 papers. Over the past several years, Dom has been helping to advance the science and application of ketogenic metabolic therapy (KMT) with colleagues at Moffitt Cancer Center, particularly focusing on using KMT to enhance immune-based therapies for certain types of cancers. Dawn asks Dom about this collaboration. [00:05:04] Dawn explains that ketogenic metabolic therapy is a dietary approach that focuses on a high-fat/low-carb diet to reduce glucose availability for cancer cells, potentially slowing their growth and improving treatment outcomes. It has been explored as a complimentary treatment for a variety of cancers including gliomas by shifting the metabolism of tumor cells away from glucose. Dawn asks Dom to explain what is involved in KMT. [00:06:58] Dawn clarifies that KMT requires less than 20-25 grams of carbohydrates per day, and that ketosis is a metabolic state in which the body switches from glucose metabolism to metabolizing fats in the form of ketones. Dawn goes on to explain that cancer cells typically consume glucose at a higher rate than normal cells. However, cancer cells are also very adaptable, and Dawn asks Dom to talk about this feature of cancer cells. [00:09:14] Ken explains that KMT has shown the most promise in treating high-grade gliomas, or brain cancers, such as glioblastoma, which is the most aggressive primary brain tumor in adults. Ken explains that Dom was part of a massive review titled “Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma,” which proposed guidelines for the management of glioblastoma based on an understanding of cancer as a metabolic disease, particularly involving mitochondria. Ken asks Dom to talk about this review. [00:11:21] From a patient advocacy perspective, Ken notes that the review recommends that there should be an aggressive education campaign that can arm patients with knowledge about KMT and other novel therapies. Ken asks Dom to talk about that recommendation. [00:13:15] Ken asks about the process of cutting the review from upwards of 200 pages down to around 50 pages with 49 authors. [00:15:04] Dawn mentions that Dom was part of another paper in 2024 titled “Targeting the mitochondrial stem cell connection in cancer treatment – a hybrid orthomolecular protocol.” Dawn explains that this paper looked at the mitochondrial stem cell connection theory (MSCC), which argues that cancer originates from chronic oxidative phosphorylation insufficiency in stem cells. This insufficiency leads to the formation of cancer stem cells and abnormal energy metabolism ultimately resulting in malignancy. There were 16 research centers and organizations involved in this paper which introduced a hybrid orthomolecular protocol to target the mitochondrial stem-cell connection. Dawn asks Dom to give an overview of MSCC. [00:18:26] Dawn explains that in this paper Dom and his co-authors propose a protocol that would enhance oxidative phosphorylation and inhibit the primary fuels of cancer, glucose and glutamine. This would target both cancer stem cells and metastasis. Dawn asks Dom to explain why this concept is attracting so much interest as a potential therapeutic approach for cancer. [00:20:48] Dawn asks if Dom could discuss the orthomolecular protocol, which is an approach that focuses on preventing and treating diseases by correcting nutritional balances in the body. [00:24:41] Ken asks if the proposed dietary intervention in the orthomolecular approach is different from a standard or typical ketogenic diet. [00:26:48] Ken shifts the discussion to talk about ketone supplements, explaining that Dom recently published a paper titled “Divergent hepatic outcomes of chronic ketone supplementation.” Ken goes on to explain that ketone salts preserve liver health, while some ketone esters and precursors appear to drive inflammation and steatosis. There is a lot of interest in ketone supplementation because they substantially elevate circulating ketones without having to restrict carbohydrates as strictly. The problem, as Ken explains, is that the long-term hepatic safety of ketone supplements remains unclear. In the aforementioned paper, Dom's rodent study evaluated the formulation-dependent impact of chronic ketone supplementation on liver histopathology, inflammatory signaling and systemic biomarkers. Ken asks Dom to discuss this paper and its findings and to give an overview of the various ketone supplements currently available. [00:30:49] Dawn asks Dom to dive into the methods and findings of the rodent study. [00:34:36] Ken asks Dom what his confidence is in the rodent model used in this study, and what are the next step for further research. [00:37:47] Regarding the two different doses given to rats in the study, Ken asks Dom how these doses correlate to doses in humans [00:40:23] Ken mentions that Ben Bikman, who was our guest on episode 143, published a study in February which Dom helped co-author. It examined the effects of ketone supplements on liver function. Ken asks Dom to discuss this study. [00:44:38] Dawn pivots to ask about a joint paper that Dom did with Andrew Koutnik, who was our guest on episode 185, on carbohydrates and physical performance titled “Carbohydrate ingestion on exercise metabolism and physical performance.” Dawn asks Dom to talk about this paper, which showed that a small amount of carbohydrates is sufficient to fuel athletic performance, and how additional carbohydrate intake showed diminishing returns. [00:49:18] Ken follows up on the finding that endurance athletes who rely on carb loading can tend toward pre-diabetes. [00:51:39] Ken asks Dom about the University of South Florida trial that Dom is an advisor for on traumatic brain injury and hyperbaric oxygen therapy. [00:54:41] Dawn mentions that Dom recently had an editorial in Frontiers that gave an overview of the emerging applications of hyperbaric/hyperbaric-oxygen therapy in the treatment of different neurological disorders. Dawn asks Dom what the key points in that editorial were. [00:59:06] Dawn explains that Dom recently gave a lecture at IHMC (available to view on IHMC's YouTube page), on traumatic brain injury and the populations at greatest risk in that context. Dawn asks Dom to give an overview of how an injury to the brain can result in neurometabolic crisis. [01:02:53] Ken asks Dom, excluding occupation demographics, what demographic is most at risk for traumatic brain injury (TBI) and why. [01:04:45] Ken mentions that it is understandable the risk that young people face with TBI due to the activities that young people engage in. Older people, however, have increased risk of TBI from falling as well as an additional age-related biological component that young people are not subject to. Ken asks Dom to elaborate on this. [01:07:12] Dawn mentions that several years ago, Dom and his wife bought some acreage in the countryside and started farming and asks Dom how the farm life is going. [01:07:57] Dawn closes the interview asking how Dom's wife is doing.

How many carbs should you eat on a ketogenic diet? Do ketone levels matter? And why do cravings hit so hard? Is Dairy recommended?In this Metabolic Mailbag episode, registered dietitian and medical student Temple Stewart breaks down some of the most common challenges people face when starting and maintaining a ketogenic diet, especially for PCOS (PMOS), metabolic health, and long-term sustainability.Temple brings a unique perspective to this conversation, combining clinical nutrition experience with current medical training and a deep focus on women's metabolic health. Her approach is practical, individualized, and grounded in helping people build strategies they can realistically sustain over the long term.In this episode, we cover:Ketogenic therapy and the menstrual cycleCravings and the “sugar dragon”PCOS and therapeutic ketone levelsDairy, protein, and hungerVegetarian keto challengesCGMs and ketone testingHow to personalize a ketogenic approach long termOne of the biggest takeaways: successful ketogenic therapy is about understanding your own metabolism, building sustainable habits, and learning which strategies help you feel your best over time.

Kristina Cook shares how lifelong anxiety and postpartum depression, combined with her daughter Genevieve's escalating, unpredictable mood instability, rage, suicidality, and mania, pushed their family into crisis despite years of therapy, medications, and an 11-year-old's 16-week hospital in-treatment stay with a discharge plan involving notifying police. After an RFK Jr. press conference led her to Casey and Calley Means' message in Good Energy, Kristina removed ultra-processed foods and refined ingredients and saw rapid improvements in sleep, pain, and her daughter's behavior. Later, after hearing Dr. Chris Palmer describe ketogenic therapy for severe mental illness, Kristina and her daughter transitioned to keto, endured a brief detox period, and then experienced dramatic mental clarity; Genevieve reached remission and came off medication, and Kristina also saw major weight and anxiety relief. Kristina now studies nutrition, works with the Metabolic Collective, and advocates for accessible metabolic therapies for families. Good Energy (book by Casey Means & Callie Means)  metaboliccollective.org  Metabolic Mind — https://www.metabolicmind.org/ Kristina on X (Twitter): @KristinaCook https://x.com/KristinaCo9561 The Better Humans Project — Kristina's Instagram and Facebook pages  https://www.instagram.com/thebetterhumansproject?igsh=MTM4YTkyZ3duejdjbw==

Dr. Ian Lake has worked as a doctor in the NHS for nearly four decades, most of this time as a general practitioner. After being diagnosed with LADA Type 1 Diabetes at age 36 and managing it conventionally for 20 years, he adopted the low carb diet and has been following it for the past 10 years. He is a founding member of the Public Health Collaboration in the U.K. and has conducted several important research projects investigating the connection between low carb diets and human health. He has also worked with Dr. Tro and others to produce the Type 1 Consensus Statement. In this episode, Drs. Tro and Ian talk about… (00:00) Intro (03:30) The mental and physical health challenges faced by Type 1 Diabetics and how these challenges have traditionally been dealt with (13:44) Ketoacidosis, what insulin does, and modern methods/dietary reccomendations for controlling Type 1 Diabetes (25:45) How Dr. Lake's colleagues have responded to his ideas regarding Type 1 and ketogenic diets (38:00) Dr. Lake's new book, Shifting Gears, on the need to move from a glucose-centric view of Type 1 to a holistic, healthy human being perspective (50:23) Outro For more information, please see the links below. Thank you for listening! Links: Please consider supporting us on Patreon: https://www.lowcarbmd.com/ Resources Mentioned in this Episode: Dr. Ian Lake's last appearance on the LCMD Podcast: https://lowcarbmd.com/podcast/episode-368-dr-ian-lake/ Dr. Ian Lake: X: https://twitter.com/idlake Type1Keto: https://type1keto.com Type 1 Consensus Statement: https://journalofmetabolichealth.org/index.php/jmh/article/view/100 Case report: Ketogenic diet alleviated anxiety and depression associated with insulin-dependent diabetes management: https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2024.1404842/full Shifting Gears (New Book): https://type1keto.com/product/shifting-gears-the-1000-mile-ride-that-changed-my-mindset-on-type-1-diabetes/ Dr. Brian Lenzkes:  Website: https://arizonametabolichealth.com/ Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author Dr. Tro Kalayjian:  Website: https://toward.health Twitter: https://twitter.com/DoctorTro IG: https://www.instagram.com/doctortro/ Toward Health App Join a growing community of individuals who are improving their metabolic health; together.  Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.  Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888  Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US Learn more: https://toward.health/community/

What if the most powerful tool for mental health recovery isn't a medication — it's your metabolism?  Dr. Erin Louise Bellamy joins Dr. Vera Tarman for a deep dive into ketogenic metabolic therapy: what it is, how it works, and why it may be one of the most underutilized interventions in both psychiatric care and food addiction recovery.  Dr. Bellamy is a chartered psychologist, CEO of IKRT (International Ketogenic Research & Therapy), and a research fellow at the University of East London. She has been researching and applying ketogenic metabolic therapy in clinical settings since 2014, with a background that bridges eating disorders, psychiatric research, and metabolic health.  In this episode, Vera and Erin discuss:  How Erin went from eating disorder and alexithymia research to ketogenic metabolic psychiatry — and why the field's "biopsychosocial" model was missing the bio  The difference between metabolic psychiatry, ketogenic therapy, and therapeutic carbohydrate restriction — and why the terminology matters  What carbohydrate range actually produces therapeutic ketosis (and why "dirty keto" doesn't cut it)  The shared mechanistic pathways across psychiatric diagnoses — including mitochondrial dysfunction, insulin resistance, and neuroinflammation  Why antipsychotic medications create metabolic dysfunction, and how ketogenic therapy can help offset those side effects  The GABA/glutamate shift that makes ketones naturally anxiolytic — and why this may work differently than the serotonin model of depression  The "buffer effect": what it feels like to be in ketosis when you're a food addict — and why some people describe it as a pane of glass between themselves and a trigger food  How ketogenic therapy compares to GLP-1 medications (Ozempic/Wegovy) for reducing food noise — and Erin's concerns about the long-term research  MCT oil vs. exogenous ketones: when each is useful, and when exogenous ketones are counterproductive  Applying ketogenic therapy to people with ADHD, bipolar disorder, and co-occurring food addiction  How to support vegan or plant-based clients who want to pursue ketogenic therapy  Why the first week matters most — and how to help clients through withdrawal without triggering a binge  The 19-person IKRT group program published in Frontiers — and what's coming next in the research  Connect with Dr. Erin Bellamy:  

In today's episode, we dive into the “clinical faces of fatigue.” Join Datis Kharrazian as we explore why some individuals never fully recover from illnesses or injuries, the intricate link between mood and brain energy, and why two patients with similar medical conditions like anemia can have vastly different experiences of fatigue.We'll unravel how mitochondrial dysfunctions, both inherited and acquired, lie at the heart of chronic fatigue, depression, fibromyalgia, and other conditions often resistant to simple solutions. You'll discover why bagfuls of supplements aren't enough, and how real recovery requires understanding and addressing the unique bioenergetic roadblocks each patient faces, ranging from oxidative stress and poor sleep to blood sugar imbalances and exposure to environmental toxins.Register for Chronic Fatigue and Pain Syndromes Clinical Strategies and Treatment Applications at https://pages.kharrazianinstitute.com/chronic-fatigue-and-pain-syndromesTo become a Certified Functional Medicine practitioner, visit https://kharrazianinstitute.com/⁠. Try our 7-day free trial, no credit card required. 00:00 Factors affecting mitochondrial function03:55 Optimizing patient bioenergetics basics09:27 Mitochondria and cell evolution12:33 Focus on acquired mitochondrial dysfunctions14:23 Mitochondrial ATP production process20:22 Ketogenic diet and energy pathways21:15 Ketogenic diet for chronic fatigue27:02 Exploring functional medicine resourcesSupport this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

Send us Fan MailGavin Symes is a returning guest on our show! Be sure to check out her first appearance on episode 776 of Boundless Body Radio!Gavin Symes is Registered Occupational Therapist, a Metabolic Therapy Coach, and the Founder & Chief Wizard of Wizard OT, short for Occupational Therapy. He founded Wizard OT in 2020 to provide a truly person-centered approach to therapy.At the core of their approach is the idea that each person should be treated as an individual. By considering each person's biological, psychological and social needs, they provide a tailored approach to improving every client's wellbeing. They don't assume to know ahead of time what is best for their clients, and instead, work with the individual, their family and their wider network to create an intervention.In 2010, Gavin suffered a serious head injury that left him physically and cognitively impaired. The injury made simple tasks hard and required some basic skills to be relearnt. Progress was slow and hard-won but with time, support and consistent effort, he was able to make a full recovery. The experience of having his life turned upside down by a debilitating impairment has informed everything Gavin has done throughout his career, as it is the fire that drives him to help others.Find Gavin at-https://www.wizardot.com/IG- @wizard_otFind Boundless Body at-myboundlessbody.comBook a session with us here! 

What if your body could warn you before a relapse happens? In this fascinating episode, Dr. Vera Tarman sits down with Bob Messerschmidt — biomedical engineer, inventor, and one of the architects behind the original Apple Watch's health-sensing technology — to explore a surprisingly simple but powerful biomarker: the erythrocyte sedimentation rate (ESR). Bob is the founder of Core Health and has developed an FDA-registered at-home device that tracks chronic low-grade inflammation over time. For those of us in the food addiction and recovery world, this conversation opens a compelling new door: could inflammation tracking be the missing feedback loop for people working to stay abstinent from ultra-processed foods?

Ketogenic diets can help some obese people lose a significant amount of weight when their health is at risk. But in recent months, social media influencers have also credited these very low-carb diets with a far more remarkable effect: treating, or even curing, schizophrenia. Is there any truth to this claim, or is it just another social media fad racing ahead of the evidence?

Send us Fan MailJohn LaSpina is a returning guest on our show! Be sure to check out his appearances on episodes 575, 582, 606, 718, 834, and 912 of Boundless Body Radio!John LaSpina, known online as Carnivore Teacher Alpha, is a retired educator, nutrition researcher, and creator of the popular Carnivore Teacher platforms where he teaches people around the world about the proper human diet and metabolic health.After spending more than three decades in the classroom teaching middle school, John turned his passion for education toward nutrition science, human biology, and the hidden chemistry of modern food.Through his books, interviews, and videos, he helps people understand how ultra-processed foods and plant toxins can affect the body-and how returning to nutrient-dense animal foods can restore health and vitality. John lives in Florida with his husband Doug and continues to teach, write, and share what he learns with a growing global community.He is the author of several books, including The Carnivore Teacher: A Meat-Based Education for Total Transformation, Processed To Death: The Truth About Ultra-Processed Food and How to Escape Its Grip, and his latest book Beyond Oxalates: The Complete Guide to Plant ToxinsFind John at-YT@- Carnivore Teacher AlphaIG- @carnivoreteacherjohnLK- @Carnivore TeacherFind Boundless Body at-myboundlessbody.comBook a session with us here! 

People with treatment-resistant depression and anxiety are seeing real improvements through ketogenic therapy. Now there's real-world clinical data to back it up.In this interview, Dr. Bret Scher sits down with Dr. Erin Bellamy to discuss her newly published findings from a clinical program bringing ketogenic therapy into everyday mental health care.While this was not a randomized controlled trial, the results offer an important look at how these interventions may work in everyday clinical practice, with meaningful improvements reported across both depression and anxiety measures.In this conversation, you'll learn:What the study found and how to interpret the resultsThe difference between real-world evidence and randomized trialsWhy some individuals were able to achieve clinically meaningful improvements, including remissionThe role of structure, education, and ongoing support in implementing ketogenic therapyCommon challenges people face and how group support can help navigate themHow ketogenic therapy can be personalized based on individual needsThe real-life improvements participants experienced in mood, anxiety, daily functioning, and quality of lifeDr. Bellamy also shares powerful insights from her clinical experience, including how individuals with long-standing, treatment-resistant symptoms were able to make meaningful lifestyle changes, challenging the idea that people with mental health conditions cannot adhere to dietary interventions.Looking ahead, Dr. Bellamy is launching a new study through the Metabolic Psychiatry Scholar Award to further explore and scale this approach.Learn more about the impact of metabolic therapies on depression and mood disorders on our Depression Topic Page: https://www.metabolicmind.org/resources/topics/keto-for-depression/

Send us Fan MailNicole Laurent is one the most featured returning guest on our show, so be sure to check out all her appearances on episodes 248, 343, 438, 538, and 744 of Boundless Body Radio!Nicole Laurent, LMHC, has been a licensed mental health counselor in Washington state for almost two decades. Her current practice focuses on helping her clients with anxiety, depression, and other mental health issues transition to a ketogenic diet or uses other nutritional therapies to complement their psychotherapy work.She holds several specialized training certifications, allowing her to work with underlying biological factors in mental illness. Nicole works with clients via telehealth, and helps people explore medication-free options for their mental health using research and evidence-based nutritional and functional psychiatry so that people can get their lives back without side effects or dependence on big pharma.In 2021, she created MentalHealthKeto.com, a blog devoted to educating people about ketogenic diets for mental health and neurological issues.Nicole is one of seven pioneers of Metabolic Psychiatry recognized by the Baszucki Brain Research Fund and the Milken Institute and has been given the Metabolic Mind Award in 2022Find Nicole at-https://mentalhealthketo.com/Study- Awareness and best practices in using ketogenic therapy to treat serious mental illness: a modified Delphi consensusIG- @mentalhealthketoTW- @KetoCounselorLK- Nicole Laurent, LMHCFB- @thatketocounselorFREE E-BOOK!Google Scholar link set with keyword "ketogenic"!Find Boundless Body at-myboundlessbody.comBook a session with us here! 

Are we destined for cognitive decline as we age, or do we have more control than we think?In this conversation, Dr. Bret Scher sits down with neuroscientist and researcher Dr. Tommy Wood to explore a powerful shift in how we think about brain health, aging, and dementia prevention.Dr. Wood challenges the common belief that cognitive decline is inevitable, highlighting how lifestyle, environment, and daily habits can meaningfully shape our brain's trajectory over time. He introduces his “3S Framework”—Stimulus, Supply, and Support—to explain how brain function is built, maintained, and optimized across the lifespan.In this interview, you'll learn:Why cognitive decline isn't inevitableHow mindset and engagement can influence brain agingThe role of metabolic health and energy supply in brain functionHow nutrition, sleep, exercise, and social connection interact to support the brainWhere ketogenic therapy and ketones may fit into brain health and cognitive declineHow to navigate modern challenges like technology, AI, and information overload from a brain health perspectiveDr. Wood also shares insights from his upcoming book, The Stimulated Mind, offering a practical framework to help individuals “future-proof” their brain and stay sharp in an ever-changing world.The key takeaway: brain health isn't about a single intervention. It's about consistently engaging, fueling, and supporting the brain in ways that promote resilience over time.

Send us Fan MailDr. Maya Schumer is a psychiatric neuroscientist and postdoctoral fellow at McLean Hospital and Harvard Medical School, and she is a first-time guest on Boundless Body Radio!Dr. Schumer's work focuses on understanding the brain network dynamics underlying bipolar disorder, particularly mania. Dr. Schumer's path is both professional and personal, as she has lived with bipolar disorder for over a decade. After years of persistent symptoms despite extensive treatment, she began exploring metabolic approaches to mental health, including ketogenic therapy, which profoundly changed her own trajectory.This lived experience informs her scientific work and advocacy, where she is passionate about bridging the gap between research and real-world healing. In addition to her research, Dr. Schumer is actively involved in national and international efforts to integrate lived experience into psychiatric science.She serves on committees within the International Society for Bipolar Disorders and the Society of Biological Psychiatry, and she is dedicated to advancing more personalized, biologically grounded approaches to mental health care.Through her research and public speaking, Dr. Schumer aims to expand how we understand and treat bipolar disorder—bringing together neuroscience and lived experience to help others find more effective paths to remission and stability.Find Dr. Maya Schumer at-TW- @MayaSchumerLK- Maya SchumerGoogle ScholarNY Times Article- Can the Keto Diet Really Improve Mental Health?Find Boundless Body at-myboundlessbody.comBook a session with us here! 

Send a textMitochondria in human evolution, climate adaptation, maternal genetics, aging, and disease.TOPICS DISCUSSED:Endosymbiotic theory: Mitochondria arose from oxidative bacteria engulfed by archaea-like hosts, confirmed by phylogenetic analysis.Maternal mtDNA inheritance: Mitochondrial DNA is inherited from the mother, not the father. There are adaptive reasons for this.Haplogroups & adaptation: Tropical lineages tightly couple energy production for efficiency; northern ones uncouple to generate heat.Heteroplasmy & aging: Mixed mutant and normal mitochondria accumulate in cells, eroding energy in high-demand tissues like brain and heart.Bioenergetics in disease: Many common conditions, from Parkinson's to cancer, stem from mitochondrial-nuclear interactions rather than nuclear genes alone.Ketogenic diets: High-fat intake fuels mitochondrial beta-oxidation, which may compensate for brain energy deficits in epilepsy and bipolar disorder.Warburg effect: Cancer cells shift to glycolysis to prioritize biosynthetic building blocks over maximal ATP production.Modern mismatches: Global travel pairs ancestral mtDNA with mismatched diets and climates, raising risks for metabolic dysfunction.ABOUT THE GUEST: Douglas Wallace, PhD is a geneticist and evolutionary biologist who has studied mitochondria for over 50 years. He currently directs the Center for Mitochondrial and Epigenomic Medicine at Children's Hospital of Philadelphia and the University of Pennsylvania.RELATED EPISODE:M&M 260 | Energy Resistance Principle in Life, Healing & Disease | Martin Picard & Nirosha MuruganSupport the showHealth Products by M&M Partners: SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off. Lumen device: Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts

Ketogenic therapy for schizophrenia, bipolar disorder, and depression is gaining attention, but how can it be safely implemented into clinical practice?A newly published expert consensus provides practical recommendations to help clinicians thoughtfully apply ketogenic metabolic therapy (KMT) for serious mental illnesses.In this in-depth conversation, Dr. Matt Bernstein and Dr. Georgia Ede, both members of the expert committee, discuss how this Delphi consensus was developed, what it includes, and how it can be responsibly integrated into psychiatric practice.In this interview, they discuss:What a Delphi process is and why it was usedThe results of the Delphi process (33 consensus statements and 10 clinical recommendations)Who may be appropriate candidates for KMTAbsolute and relative contraindicationsRecommended laboratory screening and monitoringHow long a trial should last before assessing efficacyHow clinicians can personalize implementation safelyImportantly, the authors emphasize that ketogenic metabolic therapy is not a replacement for standard psychiatric treatment. Rather, it may be considered alongside first-line therapies, particularly for individuals who have not responded adequately, cannot tolerate medications, or are seeking additional options.Reflecting on the value of this work, Dr. Bernstein shares:“I would have loved to have read this six years ago when I was starting to think about implementing these types of practices. It would have given me confidence to charge forward… I probably would have been further along now than I am.”With randomized controlled trials ongoing and more research expected in the coming years, this consensus provides a thoughtful, experience-informed framework for clinicians who are seeing growing interest in metabolic approaches.If you are a clinician, we encourage you to read the full publication.If you are a patient or family member, consider sharing this interview and the paper with your care team to support an informed discussion about whether metabolic strategies may be appropriate in your individual case.As always, clinical decisions should be made in partnership with qualified healthcare professionals.

Send a textRosemary Laberee, aka “Ro”, has been married to her husband Pete for 35 years, and they have 4 grown kids and a grandson. Her undergraduate degree is in business, and she has a master's degree in health science. She is also senior fitness certified and a certified osteoporosis peer educator.At age 60, Ro set out to reverse osteoporosis, something her doctor had said was impossible, and they were wrong. After encountering many women who had been told that there was nothing they can do besides taking medications, she decided to take her story to Instagram. She now has a growing audience eager for information about what lifestyle changes they can make to move the needle in the right direction when it comes to bone health.Recently, she retired from her work as a consultant in a nationally acclaimed pediatric research institute in order to devote more time to building her Instagram following and spreading the word on her motto- “Build bones now; ask me how!” In her spare time, she lifts weights, reads books, and continues to learn more about human biology.Find Ro at-IG- @coffeebooksbarbellsEmail- bonebodyrecomp@gmail.comFind Boundless Body at- myboundlessbody.com Book a session with us here!

How can doctors, psychiatrists, and other health practitioners implement keto for serious mental illnesses like schizophrenia, bipolar disorder, and depression?In this short interview, Dr. Bret Scher sits down with Dr. Georgia Ede to discuss a newly published Delphi consensus paper in Frontiers in Nutrition, authored by eight experienced clinicians and researchers to establish best practices for the use of ketogenic metabolic therapy (KMT) in serious mental illnesses.Using a structured expert consensus process, the group created 33 statements clarifying things like:What ketogenic metabolic therapy isWho may be appropriate candidates?Safety considerations and medical screeningMonitoring standards and clinical implementationHow KMT can be integrated alongside standard psychiatric careThese statements were then brought to a larger group of experienced clinicians to assess broader consensus, which resulted in all 33 statements reaching the consensus threshold.This paper is not a set of formal treatment guidelines. Instead, they represent an important first step in delivering practical, experience-informed guidance for clinicians who are seeing growing patient interest in metabolic approaches to serious mental illnessAs research continues to evolve, this consensus provides a thoughtful framework for psychiatrists, primary care clinicians, therapists, dietitians, and multidisciplinary teams who wish to incorporate ketogenic metabolic therapy into individualized treatment plans.If you are a clinician interested in learning more about metabolic approaches in psychiatry, we encourage you to explore the full publication.If you are a patient or family member, consider sharing this paper with your care team to start an informed discussion about whether metabolic strategies may be appropriate in your individual case.With the clinical evidence still accumulating and randomized controlled trials ongoing, we expect this clinical guidance to continue to evolve as more data and real word experience becomes available.

Polycystic Ovary Syndrome (PCOS) is the leading cause of infertility in women, but what if the real issue isn't the ovaries?In this eye-opening conversation, Dr. Bret Scher speaks with Dr. Steven Palter, reproductive endocrinologist and founder of Gold Coast IVF, about the powerful connection between PCOS, metabolic health, mental health, and fertility.For decades, PCOS has been treated symptom-by-symptom: birth control for irregular cycles, fertility drugs for ovulation, IVF for infertility. But Dr. Palter explains why this approach often misses the root cause: insulin resistance and metabolic dysfunction.When you address the metabolic driver, everything can change.Ketogenic and low-carbohydrate dietary approaches are showing promise in improving insulin sensitivity, restoring ovulation, improving mood, and even supporting fertility, often before significant weight loss occurs. In many cases, women who were preparing for IVF are conceiving naturally after correcting their metabolic health.In this video, you'll learn:Why PCOS is best understood as a metabolic disorderHow insulin resistance drives infertility, mood changes, and long-term health risksWhy traditional “eat less, move more” advice often failsHow ketogenic therapy may restore ovulation and improve fertilityThe connection between PCOS, depression, and binge eatingWhy GLP-1 medications aren't the same as metabolic repairIf you or someone you know is struggling with PCOS, infertility, or unexplained hormonal symptoms, this episode offers a hopeful and science-based perspective on what's possible when metabolic health becomes the priority.As always, consult your healthcare provider before making significant dietary changes.

The Ketogenic diet is popular for weight loss in humans, but does it work, and can it work with my grass-eating horses? The simple answer is yes, and you don't need to make them carnivores! A ketone, also known as beta-hydroxybutyrate, can be produced in two ways in horses. The first is the bacterial breakdown of cellulose in their hindgut. I have discussed this elsewhere, and it is the primary source of this ketone. The second way occurs when a horse consumes its body fat, which then forms ketones. The most common way to force a horse to consume its body fat is to starve them, and this is exactly what happens in starvation. But we don't need to go that far. What starts the horse making its own ketones is deciding to stop eating. There are two ways to do this: feed adequate amounts of high-quality protein, and stop feeding excess glucose (sugar) in the form of starch found in grains, grain mixes, balancers, supplements, treats, and excess hay. Believe it or not, but the more you feed food filled with glucose, the hungrier the horse will become. It is a paradox, but it is essential to understand if you want your horse to lose body fat, maintain muscle, become healthy, and remain sound. ********** Community.TheHorsesAdvocate.com is a place to learn about horses, barns, and farms. Its information is free, and a membership option lets horse owners attend live meetings to ask questions and deepen their understanding of what they have learned on the site. Membership helps support this message and spread it to everyone worldwide who works with horses. The Equine Practice, Inc. website discusses how and why I perform equine dentistry without immobilization or the automatic use of drugs. I only accept new clients in Florida. Click here to make an appointment. The Horsemanship Dentistry School is a place for those interested in learning how to perform equine dentistry without drugs on 97% of horses. Thank you for sharing and "Helping Horses Thrive In A Human World."

Send a textDr. David G. Harper is a returning guest on our show! Be sure to check out his first appearance on episode 319 of Boundless Body Radio!Dr. David G. Harper is a health educator and cancer researcher, and has studied the impact of diet on human health for many years. The culmination of that extensive work is the BioDiet, a ketogenic food regimen that he created in 2012. The significant weight loss and health improvements he experienced led Dr. Harper to counsel thousands of people on the BioDiet, in clinical trials and on a personal basis, with consistent, impressive results.He is the author of the bestselling book BioDiet: The Scientifically Proven, Ketogenic Way to Lose Weight and Improve Health, which has become an international best-seller, reaching as high as #18 globally for books overall on Amazon.com. Dr. Harper is an Associate Professor of Kinesiology at the University of the Fraser Valley and a Visiting Scientist at the BC Cancer Research Center, Terry Fox Laboratory.He holds a Ph.D. from the University of British Columbia and completed a post-doctoral fellowship in comparative physiology at the University of Cambridge. He was on the Scientific Advisory Board of the Canadian Clinicians for Therapeutic Nutrition and a member of the Institute for Personalized Therapeutic Nutrition. He is a great friend and a great human being!Find Dr. Harper at-https://www.biodiet.org/LK- Dr. David G. HarperFB- @Dave HarperReciprocal Meat Conference June 21-24, 2026 in Amarillo, TX!How It's Made - Canola Oil! UNBELIVABLY DISGUSTING.Check out his amazing talk at Keto Salt Lake 2022!Find Boundless Body at-myboundlessbody.comFind Boundless Body at- myboundlessbody.com Book a session with us here!

In this powerful interview, Dr. Bret Scher speaks with Dr. Robin Engelhardt, a German researcher and PhD in psychology, who is launching a pilot study investigating ketogenic metabolic therapy as a treatment for PTSD and complex PTSD.Using his own personal experience of healing from PTSD through nutritional ketosis, Dr. Engelhardt is now launching a pilot study to explore whether this approach can help others. His pilot study will test feasibility, safety, and symptom response, paving the way for future randomized controlled trials.

Can a ketogenic diet help with depression when other options have failed? Emerging suggests the answer may be yes.In this video, Dr. Bret Scher shares the latest clinical data on ketogenic therapy for depression, including two new studies showing meaningful improvements, even remission, in people with moderate to severe symptoms. For individuals struggling with treatment-resistant depression, these findings offer real hope and open the door to a new therapeutic pathway: metabolic interventions that target brain energy.In this video, you'll learn:How ketosis may support brain function and mental healthWhat two new pilot studies reveal about keto for depression and anhedoniaHow researchers are beginning to rethink the metabolic roots of mood disorders

Send us a textBenjiman Boyd is a graduate researcher and metabolic health advocate dedicated to exploring the intersection of diet and neurometabolism.With over seven years of personal experience successfully managing ADHD and depression through a ketogenic lifestyle, he brings a unique blend of lived insight and academic rigor to the field. Currently, his thesis work investigates the potential of the ketogenic diet as a treatment for Borderline Personality Disorder.Benjiman's ultimate mission is to obtain clinical licensure and certify in Ketogenic Metabolic Therapy, with the specific goal of bringing these life-changing metabolic interventions to patients across Upstate New York.He is a good friend and co-collaborator with our friend and former podcast guest Steven T, and was recently hosted on my dear friend Robyn Dobbins' amazing podcast, KetoBiography.Find Benjiman at-TW- @benjiboyd4LK- @benjiman boydFB Group- Metabolic CollectiveBenjiman's Thesis- Ketogenic Therapy: A Metabolic Intervention for Treatment-Resistant Borderline Personality DisorderFind Boundless Body at- myboundlessbody.com Book a session with us here!

In this special Metabolic Mailbag episode, cardiologist Dr. Bret Scher steps into the hot seat to answer your most pressing questions about ketogenic therapy, heart health, and metabolic markers. Drawing directly from listener questions, this conversation tackles the confusion and concern many people face when lab results change after starting a ketogenic diet.

On this episode of The Dr. Hyman Show, I'm rejoined by psychiatrist and Harvard professor Dr. Chris Palmer for a conversation that challenges how we've been taught to think about mental illness. For decades, psychiatry has focused on managing symptoms—often without asking what's actually driving them. We discuss a different way of understanding mental health, one that looks beyond diagnostic labels and considers how whole-body biology influences brain function, resilience, and recovery.  Watch the full conversation on YouTube or listen wherever you get your podcasts. In this conversation, we explore: • Why mental illness is rising alongside obesity, diabetes, and other chronic diseases • How whole-body biology influences mood, focus, and emotional resilience • The link between inflammation, metabolic dysfunction, and conditions like depression and bipolar disorder • How nutrition, testing, and lifestyle changes can support real recovery If mental health has ever felt close to home for you or someone you care about, this conversation is meant to offer clarity, compassion, and a place to start. This episode was recorded live at the Eudēmonia Summit, a conference exploring the future of health, longevity, and well-being. Learn more at eudemonia.net. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hymanhttps://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman's Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Timeline, BON CHARGE, Qualia, Paleovalley, Pique and Korrus. Receive 35% off a subscription at timeline.com/drhyman. Upgrade your routine. Head to boncharge.com/hyman and use code DRMARK for 15% off. Go to qualialife.com/hyman and use code HYMAN at checkout for an extra 15% off. Head to paleovalley.com and use code HYMAN20 for 20% off your first order. Secure 20% off your order plus a free starter kit at piquelife.com/hyman.Upgrade your lighting. Enjoy 15% off at korrus.com/drhyman. (0:00) Introduction to mental health crisis and guest Dr. Christopher Palmer (1:31) Eudaimonia Summit and psychiatric revolution (3:06) Traditional and systemic views on psychiatric disorders (7:23) Misconceptions and stigma surrounding mental disorders (10:15) The impact of childhood experiences on mental health (13:28) Root causes of mental illness: Inflammation and brain dysfunction (21:23) Metabolic dysfunction in mental illness (24:15) Significance of metabolism in mental health (27:47) Metabolic nutritional psychiatry and premature mortality (32:34) The mental health revolution and metabolic treatments (34:16) Ketogenic diet as a potential treatment for mental disorders (37:18) Functional and network medicine in mental health (41:13) Biomarkers and potential treatments in metabolic mental health (49:07) Ketogenic therapy and its anti-inflammatory effects (50:12) Historical and emerging paradigms in psychiatry (54:38) Integrating functional medicine into mainstream psychiatry (56:20) Addressing chronic disease in national health discussions (58:22) Closing remarks and further resources (59:02) Podcast outro and call to action

In this eye-opening episode, we explore one of the most exciting shifts in modern mental health: the discovery that mental health is deeply rooted in metabolic health. When the brain's energy supply falters, everything from mood to memory to emotional resilience can be affected — and new research is revealing how nutrition and lifestyle can restore balance. Our guest, Moira Newiss, is a BANT-registered nutritional therapist, health coach, and accredited ketogenic metabolic therapy expert who specializes in brain energy — a newly recognized root cause of many mental health challenges. Moira helps clients understand what's happening in their biology and guides them through simple, practical changes that spark real transformation. Her work is grounded in hope, clarity, and the belief that people can not only feel better but truly get their lives back on track. Together, we unpack how ketogenic diets can provide a cleaner, more efficient fuel source for the brain through ketones, helping stabilize brain energy and improve mental well-being. Moira also explains why diet is only one piece of the puzzle — and how sleep, light, movement, and stress balance each play essential roles in optimizing brain metabolism.     Want to watch this episode on YouTube? Click here. Subscribe if you'd like to catch all new episodes live and participate with our guests directly.   Want to learn more about becoming an FDN? Go to fdntraining.com/resources to get our best free workshops and mini-courses! Where to find Moira Newiss: Website: moiranewiss.co.uk Instagram: @moiranewiss YouTube: @moiranewiss  

Send us a textBronson Dant is a returning guest on our show! Be sure to check out his appearances on episode 271, 487, 687, and 828 of Boundless Body Radio!Coach Bronson Dant has been coaching and training people in health and fitness for over 13 years. In 2018 Bronson discovered how a carnivore-based diet was the secret to extreme optimization of his metabolic health and performance. Since then, he has designed specific methods to use both nutrition and fitness to radically improve the lives of hundreds of people all over the world.Bronson has numerous certifications and extensive training in health and fitness. He is a frequent guest and subject matter expert on health and fitness podcasts and YouTube channels, including his own YT channel at Coach Bronson. He is also a prolific speaker and presenter at health conventions all over the US.Bronson is the author of several books, including The Ultimate Ketogenic Fitness Book: The complete guide to optimizing Keto for a better quality of life, and his most recent book Body Confident: Unlock the secret to strength, independence, and lifelong badassery using the F2 MethodFind Bronson at-https://coachbronson.com/IG- @coach.bronsonYT- @coach.bronsonBlog- https://coachbronson.com/blog/Study- Substrate-Corrected VO₂Models for Improved Interpretation of Movement EconomyFind Boundless Body at- myboundlessbody.com Book a session with us here!

Shannon Davis, a Registered Dietitian Nutritionist with more than 19 years of experience specializing in metabolic health and insulin resistance. She's a founding board member of the American Diabetes Society, an Insulin IQ Coach, and the founder of a successful virtual metabolic health practice where she's helped nearly a thousand people reverse insulin resistance, lose weight, and even put type 2 diabetes into remission. Shannon's background spans dialysis, organ transplant, bariatrics, and pharmaceutical sales — giving her a unique perspective on why food, not medication, is the real solution to most dietary conditions. She's been featured on over 50 podcasts as an expert in metabolic health, and when she's not helping people transform their lives, you'll find her in the gym doing CrossFit or spending time riding horses — her lifelong passion. Instagram: https://www.instagram.com/sldavis6580 X: https://x.com/fittoeat6580 YouTube: https://youtube.com/@shannondavis1619 Facebook: https://www.facebook.com/shannon.davis.9279 Website: https://shannonfeelgreat.com/ Timestamps: 00:00 Trailer 00:53 Introduction 05:31 Renal care challenges and ethics 09:11 Kidney health and low-carb diets 10:41 Keto and kidney care 13:44 Dialysis conflict of interest 18:39 Diabetes advocacy and carnivore 21:16 Ketogenic diets and diabetes 24:02 Preventing heart disease 28:16 Diet wars and social media 31:26 Better living through medication 34:04 Platform censorship frustrations  37:14 Grassroots health movement challenges 42:51 AI transforming pharmaceutical marketing 43:30 Drug industry priorities  49:16 Low carb diet and cholesterol 50:29 Where to find Shannon 53:43 United in the fight Join Revero now to regain your health: https://revero.com/YT Revero.com is an online medical clinic for treating chronic diseases with this root-cause approach of nutrition therapy. You can get access to medical providers, personalized nutrition therapy, biomarker tracking, lab testing, ongoing clinical care, and daily coaching. You will also learn everything you need with educational videos, hundreds of recipes, and articles to make this easy for you. Join the Revero team (medical providers, etc): https://revero.com/jobs ‪#Revero #ReveroHealth #shawnbaker  #Carnivorediet #MeatHeals #AnimalBased #ZeroCarb #DietCoach  #FatAdapted #Carnivore #sugarfree Disclaimer: The content on this channel is not medical advice. Please consult your healthcare provider.

Beth Zupec-Kania is a leading global expert in ketogenic therapy, known for her decades of clinical experience and clear, compassionate guidance. A registered and certified dietitian-nutritionist, she has spent more than 30 years helping clinicians, patients, and families use therapeutic ketosis safely and effectively for neurological, psychiatric, metabolic, and even select cancer-related conditions. In this episode, Dr. Tro, Dr. Brian, and Beth talk about… (00:00) Intro (02:23) What The Charlie Foundation is and how Beth first became involved (05:09) The frustrations Beth faced as a nutritionist promoting an, at the time, very taboo diet in the ketogenic diet (09:37) How Beth initially came to see the power of keto as a therapy for people with epilepsy (12:16) The evolution of the keto diet over the decades (18:40) How the keto diet can be life changing for children with epilepsy (27:28) Epilepsy patients weaning off of the keto diet (30:22) Why a supplemental or drug cannot replace the keto diet for epilepsy patients (32:44) How sugar and the microbiome play into epilepsy and seizure disorders (41:28) Beth's personal experience with the ketogenic diet (47:38) HRT, women's health, and the keto diet (51:54) Addiction and denial (56:55) Fatty liver disease and the keto diet (01:00:02) The new dietary guidelines (01:04:04) Eating REAL fats (01:05:52) For more information, please see the links below. Thank you for listening! Links: Please consider supporting us on Patreon: https://www.lowcarbmd.com/ Beth Zupec-Kania: The Charlie Foundation: https://charliefoundation.org/ Website: https://www.bethzupeckania.com/ Keto Mastery: https://www.ketomastery.pro/ Dr. Brian Lenzkes:  Website: https://arizonametabolichealth.com/ Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author Dr. Tro Kalayjian:  Website: https://www.doctortro.com/ Twitter: https://twitter.com/DoctorTro IG: https://www.instagram.com/doctortro/ Toward Health App Join a growing community of individuals who are improving their metabolic health; together.  Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.  Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888  Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US Learn more: https://doctortro.com/community/ 

Dr. Caroline Roberts is a board-certified physician and leading clinician at Virta Health, where she helps patients reverse type 2 diabetes through evidence-based, nutrition-focused care. Known for her compassionate approach and expertise in metabolic health, Dr. Roberts empowers individuals to reclaim their health using sustainable, real-world strategies. Her work blends cutting-edge science with practical guidance, making her a standout voice in the movement to transform diabetes care. In this episode, Drs. Tro, Brian, and Caroline talk about… (00:00) Intro (02:44) How Dr. Caroline discovered the power of keto for reversing Type 2 diabetes and controlling Type 1 diabetes (08:46) Why you don't need to eat 120 grams of carbs per day (10:36) DKA risk in Type 2 patients (18:15) Type 1 patients and low carb diets (23:36) Ketogenic diets and cardiovascular outcomes (30:44) Why the medical world has been so slow to acknowledge the benefits of keto and low carb diets (44:08) Dietary sustainablility  (45:58) CGMs, finger sticks, and keto diets (54:36) Long term patient outcomes from Virta patients (58:57) Keto and psychiatric health (01:04:08) Outro For more information, please see the links below. Thank you for listening! Links: Please consider supporting us on Patreon: https://www.lowcarbmd.com/ Dr. Caroline Roberts: Papers:  https://www.researchgate.net/profile/Caroline-Roberts-17 Virta Health: https://www.virtahealth.com Dr. Brian Lenzkes:  Website: https://arizonametabolichealth.com/ Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author Dr. Tro Kalayjian:  Website: https://www.doctortro.com/ Twitter: https://twitter.com/DoctorTro IG: https://www.instagram.com/doctortro/ Toward Health App Join a growing community of individuals who are improving their metabolic health; together.  Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.  Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888  Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US Learn more: https://doctortro.com/community/ 

David Baszucki is the founder and CEO of Roblox. TIME named Roblox one of the “100 Most Influential Companies,” and it has been recognized by Fast Company for innovation on their “Most Innovative Companies” and “Most Innovative Companies in Gaming” lists.This episode is brought to you by:Qlosi prescription eye drop used to treat age-related blurry near vision (presbyopia) in adults: https://Qlosi.com/TimAG1 all-in-one nutritional supplement: https://DrinkAG1.com/TimWealthfront high-yield cash account: https://Wealthfront.com/TimNew clients get 3.75% base APY from program banks + additional 0.65% boost for 3 months on your uninvested cash (max $150k balance. Terms apply. The Cash Account offered by Wealthfront Brokerage LLC (“WFB”) member FINRA/SIPC, not a bank. The base APY as of 9/26/25 is representative, can change, and requires no minimum. Tim Ferriss, a non-client, receives compensation from WFB for advertising and holds a non-controlling equity interest in the corporate parent of WFB. Experiences will vary. Outcomes not guaranteed. Instant withdrawals may be limited by your receiving firm and other factors. Investment advisory services provided by Wealthfront Advisers LLC, an SEC-registered investment adviser. Securities investments: not bank deposits, bank-guaranteed or FDIC-insured, and may lose value.*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dr. Dominic D'Agostino (@DominicDAgosti2) is a tenured associate professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine and a Visiting Senior Research Scientist at the Institute for Human and Machine Cognition.This episode is brought to you by: Helix Sleep premium mattresses: https://HelixSleep.com/Tim (27% off all mattress orders)Momentous high-quality creatine: https://livemomentous.com/tim (code TIM for up to 35% off)AG1 all-in-one nutritional supplement: https://DrinkAG1.com/Tim (1-year supply of Vitamin D plus 5 free AG1 travel packs)Timestamps:[00:00:00] Start.[00:14:43] Why I'm interested in ketogenic strategies for neurodegenerative prevention.[00:16:18] Mary and Steve Newport's ketone-linked temporary cognitive improvements.[00:18:18] A mechanisms overview for Alzheimer's/dementia.[00:21:25] The immune system as longevity's "fifth horseman" — and why metabolic control is key.[00:22:04] How to measure ketones and GKI.[00:23:00] Fasting vs. ketogenic diet.[00:24:18] There's nothing fishy about sardine fasting.[00:28:32] My hiatal hernia discovery and increased cancer risk concerns.[00:30:04] HSCRP as a superior biomarker to LDL for cardiovascular risk.[00:31:57] Glucose tolerance testing revelations and CGM importance.[00:31:57] Upgrading the metabolic machinery through keto without getting bored.[00:42:07] What do do if you, like Dom and me, are among the 30% who suffer from cholesterol hyperabsorption.[00:43:42] Dom's day-to-day diet regimen.[00:45:56] How Dom optimizes his aging dogs with ketones, SARMs, and supplements.[00:51:30] Supplementing for sleep disruption while fasting.[00:55:41] Why Dom doesn't have misgivings about melatonin.[00:59:15] Shingles prevention through fasting protocols.[01:00:15] Immune system modulation: Innate vs. adaptive, vegan vs. ketogenic.[01:03:54] Dom at 50-something: Current meal timing and composition.[01:05:57] Blue zone observations: Greek and Sardinian longevity habits.[01:08:16] Ketogenic diet initiation tips: MCT, electrolytes, and fasted cardio.[01:15:18] Ketone metabolic therapy for cancer.[01:18:15] The metabolic psychiatry revolution.[01:22:10] The soothing effects of hyperbaric oxygen and ketosis on seizure sufferers.[01:28:27] Metformin vs. berberine.[01:31:43] The low-dose neuroprotective potential of GLP-1 drugs.[01:34:58] NAD research: MIB-626 and stabilized forms for mitochondrial health.[01:39:48] Idebenone, CoQ10, and the Deanna protocol for ALS.[01:42:05] Dom's supplement short list: CoQ10, creatine, ketones, vitamin D, melatonin.[01:44:43] KetoNutrition.org, Metabolic Health Summit, Audacious Nutrition, veteran-focused research protocols, and other parting thoughts.*Show notes for this episode: https://tim.blog/2025/09/03/dr-dominic-dagostino-all-things-ketones/For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.