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Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we're navigating through a myriad of transformative advancements reshaping the industry. From artificial intelligence-driven research breakthroughs to strategic acquisitions in emerging therapeutic areas, these developments are setting new benchmarks in drug discovery and patient care. **Strategic Acquisitions and Expansions:** Samsung Biologics' recent proposal to acquire Swiss CDMO Polypeptide for $1.8 billion marks a significant expansion into peptide production, underscoring the growing therapeutic importance of peptides. Their specificity and efficacy make them particularly appealing for metabolic disorders such as obesity. This acquisition reflects a strategic move to capture emerging market opportunities as demand for innovative metabolic treatments rises. Eli Lilly's bold $2.8 billion acquisition of Atai-Beckley highlights the pharmaceutical industry's shifting focus towards psychedelics. As mental health disorders like depression and PTSD become more prominent, psychedelics hold great promise for new therapeutic approaches. This acquisition may pave the way for further research and acceptance of psychedelics within mainstream medicine, offering new hope for patients. Another notable development is Tempus' acquisition of Personalisis for $1.5 billion. This move strengthens Tempus' cancer treatment portfolio by leveraging genomics-driven insights, emphasizing precision medicine's critical role in oncology. **AI Integration and Technological Innovation:** Bristol Myers Squibb is doubling down on AI integration by expanding its collaboration with Nvidia to build what promises to be the most powerful AI supercomputer dedicated to life sciences. This development is pivotal as it signifies a deeper commitment to harnessing computational power in R&D. By accelerating drug discovery and optimizing clinical trial processes, AI stands to revolutionize how treatments are developed and tailored to individual patients. Overall, these developments indicate a dynamic phase characterized by technological innovation and strategic collaborations. The integration of AI into drug development processes stands out as a transformative force, promising enhanced efficiency and efficacy in bringing new treatments to market. **Regulatory Milestones and Clinical Trials:** In regulatory news, Takeda's Qdenga has achieved a milestone by becoming India's first approved dengue vaccine. This approval is crucial in addressing neglected tropical diseases, with significant implications for public health in regions where dengue is prevalent. By reducing dengue fever incidence, this vaccine could play a vital role in improving health outcomes in many tropical countries. Promising results have emerged from clinical trials across various therapeutic areas. 4D Molecular Therapeutics reported an 87% reduction in treatment burden for wet AMD using their gene therapy candidate 4D-150 in Phase 2b trials—demonstrating potential as a transformative approach with reduced intervention frequency. Latigo Biotherapeutics' Nav1.8 inhibitor LTG-001 outperformed Vicodin in Phase 2 trials for acute pain, offering a non-opioid alternative amidst the opioid crisis. Meanwhile, Regenxbio's five-year data on surabgene lomparvovec shows sustained efficacy in wet AMD and diabetic retinopathy—underscoring its potential as a long-term treatment option. **Financial Performance and IPO Activity:** Financially, Abbott exceeded expectations with strong sales from their device and diagnostic divisions, prompting an upward revision of their full-year profit forecast. This reflects sustained demand for innovative diagnostic solutions and medical devices—highlighting Abbott's strategic market positioning. The IPO landscape remains active with companies like Nuvox Therapeutics seeking to raise funds for advancing oxygen therapeutics targeting hypoxia-related diseases—showcasing renewed investor interest and confidence within biotech innovation. Latigo Biotherapeutics is preparing for an IPO to advance its pipeline, demonstrating a strategic response to the opioid crisis. By developing alternatives that minimize addiction risks while providing effective relief, Latigo underscores the industry's commitment to safer pain management solutions. Turning to clinical trials, Scribe Therapeutics plans a $96 million IPO to advance its CRISPR-based lipid-lowering therapies, marking significant interest in genetic solutions for cardiovascular diseases like hyperlipidemia. The precision offered by CRISPR technology could revolutionize treatment options for conditions contributing significantly to cardiovascular health burdens. **Geopolitical Influences:** Geopolitical factors are also influencing market dynamics, particularly in the UK biotech sector where IPO plans are being shaped by global uncertainties despite robust venture capital backing. This situation underscores the complex interplay between regional economic conditions and global investment trends in biotech innovation. As these trends continue unfolding across the industry landscape—from AI-driven research advancements to strategic acquisitions—the potential impact on patient care paradigms remains profound. These developments not only promise new possibilities within drug development but also influence broader healthcare delivery models aimed at improving patient outcomes globally.Support the show
Episode 387 Two big interstellar discoveries have hit the headlines. One is the discovery of the first atmosphere ever found on a small, rocky exoplanet that could host alien life. The planet LHS 1140b is about 50 light years from Earth and sits in the “Goldlocks” zone, meaning it's close enough to its star to be habitable. So what do we know about its atmosphere – and could it be just like Earth? The second story is of sugar molecules discovered in interstellar space for the first time – detected in a cosmic cloud nearly 27 light years away. Researchers believe this sugar could have formed before the solar system itself. Find out more with Senior Editor Chelsea Whyte and Space Reporter Leah Crane. To read more about these stories, visit https://www.newscientist.com/ Image credits: Chester Harman, CC BY-SA 4.0 https://creativecommons.org/licenses/by-sa/4.0 via Wikimedia Commons ESO/spaceengine.org, CC BY 4.0 https://creativecommons.org/licenses/by/4.0 via Wikimedia Commons Learn more about your ad choices. Visit megaphone.fm/adchoices
Scott and a mourning JB go through the week's biggest news stories. Hosted on Acast. See acast.com/privacy for more information.
Earnings from TSMC (TSM) are "incredibly solid," says Stephen Sopko, believing the company making two-thirds of its revenue from "leading edge" AI chips shows strength in the tech trade. He explains why the report is "incredibly promising" for the AI trade, so long as TSMC delivers on execution in meeting robust demand. One supply risk it faces: power, something Stephen calls "the primary" factor behind how the AI buildout continues from here.======== Schwab Network ========Empowering every investor and trader, every market day. Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – https://twitter.com/schwabnetworkFollow us on Facebook – https://www.facebook.com/schwabnetworkFollow us on LinkedIn - https://www.linkedin.com/company/schwab-network/ About Schwab Network - https://schwabnetwork.com/about======== Schwab Network ========Empowering every investor and trader, every market day. Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – https://twitter.com/schwabnetworkFollow us on Facebook – https://www.facebook.com/schwabnetworkFollow us on LinkedIn - https://www.linkedin.com/company/schwab-network/ About Schwab Network - https://schwabnetwork.com/about
Liz Peek highlights the rise of the Democratic Socialists of America as a significant threat to established Democraticincumbents. Young voters are flocking to radical platforms promising free services. Rahm Emanuel emerges as a blunt voice for the party, urging a challenge against these "loons." (2)STEEL BRIDGE PS
Worship with us live online at ExploreGracePoint.com/church-onlineGracePoint Church2351 Rice Creek RdNew Brighton, MN 55112
Dr Sira Karvinen - Sweat analysis | Exercise | Future applications Sira Karvinen currently works at the Gerontology Research Center, University of Jyväskylä, Finland. She is a postdoctoral researcher in a EsmiRs-study - Risk of metabolic dysfunction in middle aged women: systemic and intracrine oestrogen and microRNAs as mediating factors. --- This podcast episode is sponsored by Fibion Inc. | The New Gold Standard for Sedentary Behaviour and Physical Activity Monitoring Learn more about Fibion: fibion.com/research --- Physical Activity Researcher Podcast have created a ‘Purchase Guide for Researchers: Accelerometer-based Activity Trackers'. You can download it from here. ---
The statement from South Africa's Minister of Sport, Gayton McKenzie, addresses the unexpected and tragic death of Jayden Adams, a midfielder for Bafana Bafana and Mamelodi Sundowns, who passed away at the age of 25.His death was confirmed on July 11, 2026, occurring just weeks after he played a pivotal role in his nation's remarkable journey during the 2026 FIFA World Cup.Adams participated in all three group-stage matches, contributing to South Africa's advancement to the knockout phase of the World Cup for the first time in history. Earlier that year, he celebrated victory in the CAF Champions League with the prominent domestic club, Mamelodi Sundowns F.C.McKenzie disclosed that Adams competed while enduring profound personal sorrow during the tournament, taking to the field against the Czech Republic mere hours after receiving the news of his grandmother's passing.His body was found at a residence in Cape Town, leading local authorities to initiate an investigation. A definitive cause of death has yet to be established, and officials have requested privacy for his family during this difficult time. Tributes have been received from around the world, including messages from the South African Football Players Union (SAFPU) and FIFA President Gianni Infantino.
Oran P. Smith on South Carolina's changing attitudes about taxation
ACT expects the prison population to grow under its policy of cracking down on burglars - but says it's necessary. The Party wants a mandatory three-year prison sentence for offenders convicted of burglary three times, claiming judges are too lenient in sentencing. Deputy Leader Nicole McKee says it's clear changes need to be made, and repeat offenders will need to face punishment. "We've said - enough is enough, and we want to make some changes here, make people accountable, put victims first and give the opportunity for New Zealanders to feel safe in their own homes." LISTEN ABOVESee omnystudio.com/listener for privacy information.
Geoffrey Wawro, guest author, details how Richard Nixon derailed peace talks in 1968 through Anna Chennault, promising South Vietnamese President Thieu a "better deal" to prevent a "November surprise" for Hubert Humphrey. This move resulted in the war continuing for four more years, costing 28,000 additional American lives for essentially the same peace terms available in 1968. Under Nixon, the 1969 Battle of Hamburger Hill highlighted the continued reliance on the "search and destroy" doctrine despite its heavy costs. Waves of American troops were sent against prepared bunkers for a hill with no strategic value, sparking a domestic outcry led by figures like Ted Kennedy. Furthermore, the segment notes the ineffectiveness of South Vietnamese local militias ("Ruff Puffs"), which were often infiltrated by the Viet Cong and frequently avoided combat despite being heavily armed by the US. The Vietnam War: A Military History(5)
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Promising to crack down on crime and promoting strong ties with President Trump - right-wing populists are winning elections across Latin America. Is this a passing phase coming out of voters' economic and safety concerns or a lasting shift? And will this tie the region more to the United States? In this episode: Jose Ragas, Historian and Assistant Professor, Catholic University of Chile. Oliver Stuenkel, Associate Professor, School of International Relations, Getulio Vargas Foundation in Brazil. Javier Farje, Journalist and Historian. Host: Scott McLean Connect with us: @AJEPodcasts on X, Instagram, Facebook, and YouTube
Professor Evan Ellis reports that Keiko Fujimori is the declared victor in Peru's election, promising a pro-security, pro-U.S. agenda despite continued economic ties with China. Meanwhile, Bolivia remains unstable as President Rodrigo Paznavigates an economic crisis, currency devaluation, and ongoing pressure from former leader Evo Morales. (11)1857 VENEZUELA
HortWeek editor Matt Appleby, prospective horticulturist Douglas Newbery and technical editor Sally Drury report on the essential horticulture stories of the week.Topics for this week:National Plant Show product highlights including pre and post-biotics for soil health, a marvellous mulch and a child-size garden centre trolley.Promising news from Aeroplas pot and tray company An early look at potential Christmas hot sellersNew lines for Creation Horticulture New plant award winners at NPS and Gardeners' World LiveOne-stop shops in the UK - could this Dutch model work where it's failed in the past?Horticultural shows: what changes might be see for next year?Horticulture salaries come under the microscope in HortWeek's latest reportAnd Doug Newbery (son of Georgie Newbery of Flowers from the Farm) offers his thoughts on horticulture as a careerPodcast producer: Christina Taylor Hosted on Acast. See acast.com/privacy for more information.
In this episode, Anthony and Bernie are joined by the great Dr. Bixby to discuss the difficulties in the diagnosis and treatment of acute leukemias of mixed or ambiguous lineage (ALAL/MPAL). We discuss:- Diagnostic uncertainties and how the criteria for diagnosis have changed over the years- Data behind the optimal treatment of MPAL and uncertainties in the literature- Promising data for the FLAG-VIPR hybrid regimen and other novel treatment strategies
Worship with us live online at ExploreGracePoint.com/church-onlineGracePoint Church2351 Rice Creek RdNew Brighton, MN 55112
Ursolic acid is a natural plant compound found in foods like apple peels and herbs, and it is often promoted for muscle growth, strength, fat loss, IGF-1, mTOR signaling, and exercise performance. In this episode, we look at the human research on ursolic acid supplements, including resistance training studies, muscle biopsy data, anabolic signaling, body fat changes, strength results, and possible side effects. Does ursolic acid really help people build muscle and get stronger, or is the evidence still too limited? Let's break down what the science actually says.ReadMy Rhabdo BooKOrder onAmazon (affiliate link)Consultations https://supplementclarity.com/private-consultations/Connect With MeSupplementClarity.com YouTubeTiktokAbout Since the 1990s I've been sorting nutrition facts from fiction and helping people understand dietary supplements, using clinical research as my litmus test. I am independent and unbiased. I analyze the research so you don't have to. I wrotethe first book about exercise-induced rhabdomyolysis. I have an MS in exercise science and a BS in biology & chemistry. Disclaimer Episodes are for informationonly. I'm NOT a medical doctor. NO medical advice is given or implied. ALWAYSconsult your physician for the best health advice for you. I participate in theAmazon Associates program which means if you click on a link to amazon and makea purchase, I may make a small commission at no extra cost to you.
Pancreatic cancer is among the most deadly forms of cancer, and it can be difficult to catch early. But there's some good news: Clinical trials of a new drug called daraxonrasib found that it doubled the survival time of patients with advanced pancreatic cancer. And some oncologists are calling it a game changer—not just for pancreatic cancer, but potentially other forms of cancer too. Ira talks with oncologist Zev Wainberg, who led a clinical trial for the drug. Plus, ALS is a degenerative disease that causes patients to lose their ability to walk, swallow and eventually to breathe. Now, there's a drug for a rare genetic form of ALS that can slow the progression or even reverse some of these symptoms. Ira talks with New York Times health and science reporter Pam Belluck about this new treatment. Guests: Dr. Zev Wainberg is a co-director of UCLA Health's GI Oncology Program. Pam Belluck is a health and science reporter for The New York Times. Other episodes you may enjoy: mRNA Vaccine For Pancreatic Cancer Continues To Show Promise How do clinical trials work, and who can participate? Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Colombia's Presidential Shift Toward Security and Law and Order. Guest: Evan Ellis. Abelardo de la Espriellaappears to have won the Colombian presidency, promising a crackdown on insecurity and organized crime modeled after El Salvador's policies. His victory signals a likely return to strong security cooperation with the United States and a departure from the policies of Gustavo Petro. 91900 MEXICO
National is promising to power up New Zealand homes if re-elected, with a loan scheme to encourage households to convert to solar and make energy efficiency improvements. The Home Energy fund would offer long term loans, at below market interest rates, so people can invest in the likes of solar, battery storage and insulation. The idea is a version of a scheme proposed by LGNZ and renewable energy advocates Rewiring Aotearoa. Mike Casey from Rewiring Aotearoa spoke to Lisa Owen.
Grieving Out Loud: A Mother Coping with Loss in the Opioid Epidemic
As a veteran of the music and entertainment industry, David Nathan has helped shape the careers of A-list artists including Taylor Swift, Amy Winehouse and Ariana Grande.But behind that success, he faced a loss he never could have imagined. His son took what he believed was a Percocet, unaware it was laced with fentanyl, and died at just 19.Now, Nathan is focused on his most personal work yet: helping others navigate mental health challenges in his son's honor.What makes that mission even more meaningful is that it began with his son. Before his death, he founded an apparel company called Happy Jack, donating a portion of proceeds to support children facing mental health struggles.In this episode of Grieving Out Loud, Nathan shares his son's story, what he hopes other parents can learn, and how he's carrying forward a mission rooted in love, loss and purpose.Visit the Happy Jack website. Watch The Risks are Real live assembly here.Related episodes: Promising young entrepreneur dies after taking counterfeit PercocetThe Voice You Knew — The Story You Didn'tWhen Men Don't Cry: Confronting the Culture of Silent GriefSend us Fan MailBehind every number is a story of a life cut short, a family shattered, and a community devastated.They were...daughterssonsmothersfathersfriendswiveshusbandscousinsboyfriendsgirlfriends.They were More Than Just A Number. Support the showConnect with AngelaFollow Grieving Out LoudFollow Emily's HopeRead Angela's BlogSubscribe to Grieving Out Loud/Emily's Hope UpdatesSuggest a GuestFor more episodes and information, just go to our website, emilyshope.charityWishing you faith, hope and courage!Podcast producers:Casey Wonnenberg King & Kayli Fitz
In Real Men on Top: How Patriarchy Shapes Our Reality (Oxford University Press, 2026), Robin Dembroff shows us that we don't just live in a patriarchal world. We live in a world that patriarchy taught us to see. Patriarchy is not simply a system where men dominate women, Dembroff argues. It is a deeper reality-shaping force that legitimizes economic exploitation, political injustice, and social cruelty by dividing all of us into the rigid categories of Man, Woman, Animal, and Child. These categories are presented as natural truths, but Dembroff reveals them as man-made myths--ones that construct a reality in which being characterized as Woman, Animal, or Child marks moral degradation. By no coincidence, feminization, dehumanization, and infantilization are the very degradations used to make a man 'less of a man'. But this book is more than critique; it's also a guide to transformation especially for those grappling with what it means to be a man under patriarchy. Patriarchy's myths celebrate the identity Man, but these myths are no friend to most men. Promising strength and superiority, they instead fuel isolation, emotional repression, and relentless pressure to prove oneself while propping up systems that enrich the powerful few. Rather than deliver freedom and prosperity, these myths entrap and impoverish. Real Men on Top invites readers to see through them and, in so doing, to find new possibilities for living, relating, and becoming human. Sharp, daring, and deeply felt, Real Men on Top is a book for anyone who senses that something is deeply wrong with the way we live and wants to understand how we got here, and where we might begin the work of remaking reality. Robin Dembroff is an Associate Professor of Philosophy at Yale University Caleb Zakarin is CEO and Publisher of the New Books Network. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network
In Real Men on Top: How Patriarchy Shapes Our Reality (Oxford University Press, 2026), Robin Dembroff shows us that we don't just live in a patriarchal world. We live in a world that patriarchy taught us to see. Patriarchy is not simply a system where men dominate women, Dembroff argues. It is a deeper reality-shaping force that legitimizes economic exploitation, political injustice, and social cruelty by dividing all of us into the rigid categories of Man, Woman, Animal, and Child. These categories are presented as natural truths, but Dembroff reveals them as man-made myths--ones that construct a reality in which being characterized as Woman, Animal, or Child marks moral degradation. By no coincidence, feminization, dehumanization, and infantilization are the very degradations used to make a man 'less of a man'. But this book is more than critique; it's also a guide to transformation especially for those grappling with what it means to be a man under patriarchy. Patriarchy's myths celebrate the identity Man, but these myths are no friend to most men. Promising strength and superiority, they instead fuel isolation, emotional repression, and relentless pressure to prove oneself while propping up systems that enrich the powerful few. Rather than deliver freedom and prosperity, these myths entrap and impoverish. Real Men on Top invites readers to see through them and, in so doing, to find new possibilities for living, relating, and becoming human. Sharp, daring, and deeply felt, Real Men on Top is a book for anyone who senses that something is deeply wrong with the way we live and wants to understand how we got here, and where we might begin the work of remaking reality. Robin Dembroff is an Associate Professor of Philosophy at Yale University Caleb Zakarin is CEO and Publisher of the New Books Network. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/gender-studies
In Real Men on Top: How Patriarchy Shapes Our Reality (Oxford University Press, 2026), Robin Dembroff shows us that we don't just live in a patriarchal world. We live in a world that patriarchy taught us to see. Patriarchy is not simply a system where men dominate women, Dembroff argues. It is a deeper reality-shaping force that legitimizes economic exploitation, political injustice, and social cruelty by dividing all of us into the rigid categories of Man, Woman, Animal, and Child. These categories are presented as natural truths, but Dembroff reveals them as man-made myths--ones that construct a reality in which being characterized as Woman, Animal, or Child marks moral degradation. By no coincidence, feminization, dehumanization, and infantilization are the very degradations used to make a man 'less of a man'. But this book is more than critique; it's also a guide to transformation especially for those grappling with what it means to be a man under patriarchy. Patriarchy's myths celebrate the identity Man, but these myths are no friend to most men. Promising strength and superiority, they instead fuel isolation, emotional repression, and relentless pressure to prove oneself while propping up systems that enrich the powerful few. Rather than deliver freedom and prosperity, these myths entrap and impoverish. Real Men on Top invites readers to see through them and, in so doing, to find new possibilities for living, relating, and becoming human. Sharp, daring, and deeply felt, Real Men on Top is a book for anyone who senses that something is deeply wrong with the way we live and wants to understand how we got here, and where we might begin the work of remaking reality. Robin Dembroff is an Associate Professor of Philosophy at Yale University Caleb Zakarin is CEO and Publisher of the New Books Network. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/critical-theory
Worship with us live online at ExploreGracePoint.com/church-onlineGracePoint Church2351 Rice Creek RdNew Brighton, MN 55112
In Real Men on Top: How Patriarchy Shapes Our Reality (Oxford University Press, 2026), Robin Dembroff shows us that we don't just live in a patriarchal world. We live in a world that patriarchy taught us to see. Patriarchy is not simply a system where men dominate women, Dembroff argues. It is a deeper reality-shaping force that legitimizes economic exploitation, political injustice, and social cruelty by dividing all of us into the rigid categories of Man, Woman, Animal, and Child. These categories are presented as natural truths, but Dembroff reveals them as man-made myths--ones that construct a reality in which being characterized as Woman, Animal, or Child marks moral degradation. By no coincidence, feminization, dehumanization, and infantilization are the very degradations used to make a man 'less of a man'. But this book is more than critique; it's also a guide to transformation especially for those grappling with what it means to be a man under patriarchy. Patriarchy's myths celebrate the identity Man, but these myths are no friend to most men. Promising strength and superiority, they instead fuel isolation, emotional repression, and relentless pressure to prove oneself while propping up systems that enrich the powerful few. Rather than deliver freedom and prosperity, these myths entrap and impoverish. Real Men on Top invites readers to see through them and, in so doing, to find new possibilities for living, relating, and becoming human. Sharp, daring, and deeply felt, Real Men on Top is a book for anyone who senses that something is deeply wrong with the way we live and wants to understand how we got here, and where we might begin the work of remaking reality. Robin Dembroff is an Associate Professor of Philosophy at Yale University Caleb Zakarin is CEO and Publisher of the New Books Network. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/lgbtq-studies
In Real Men on Top: How Patriarchy Shapes Our Reality (Oxford University Press, 2026), Robin Dembroff shows us that we don't just live in a patriarchal world. We live in a world that patriarchy taught us to see. Patriarchy is not simply a system where men dominate women, Dembroff argues. It is a deeper reality-shaping force that legitimizes economic exploitation, political injustice, and social cruelty by dividing all of us into the rigid categories of Man, Woman, Animal, and Child. These categories are presented as natural truths, but Dembroff reveals them as man-made myths--ones that construct a reality in which being characterized as Woman, Animal, or Child marks moral degradation. By no coincidence, feminization, dehumanization, and infantilization are the very degradations used to make a man 'less of a man'. But this book is more than critique; it's also a guide to transformation especially for those grappling with what it means to be a man under patriarchy. Patriarchy's myths celebrate the identity Man, but these myths are no friend to most men. Promising strength and superiority, they instead fuel isolation, emotional repression, and relentless pressure to prove oneself while propping up systems that enrich the powerful few. Rather than deliver freedom and prosperity, these myths entrap and impoverish. Real Men on Top invites readers to see through them and, in so doing, to find new possibilities for living, relating, and becoming human. Sharp, daring, and deeply felt, Real Men on Top is a book for anyone who senses that something is deeply wrong with the way we live and wants to understand how we got here, and where we might begin the work of remaking reality. Robin Dembroff is an Associate Professor of Philosophy at Yale University Caleb Zakarin is CEO and Publisher of the New Books Network. Learn more about your ad choices. Visit megaphone.fm/adchoices
In Real Men on Top: How Patriarchy Shapes Our Reality (Oxford University Press, 2026), Robin Dembroff shows us that we don't just live in a patriarchal world. We live in a world that patriarchy taught us to see. Patriarchy is not simply a system where men dominate women, Dembroff argues. It is a deeper reality-shaping force that legitimizes economic exploitation, political injustice, and social cruelty by dividing all of us into the rigid categories of Man, Woman, Animal, and Child. These categories are presented as natural truths, but Dembroff reveals them as man-made myths--ones that construct a reality in which being characterized as Woman, Animal, or Child marks moral degradation. By no coincidence, feminization, dehumanization, and infantilization are the very degradations used to make a man 'less of a man'. But this book is more than critique; it's also a guide to transformation especially for those grappling with what it means to be a man under patriarchy. Patriarchy's myths celebrate the identity Man, but these myths are no friend to most men. Promising strength and superiority, they instead fuel isolation, emotional repression, and relentless pressure to prove oneself while propping up systems that enrich the powerful few. Rather than deliver freedom and prosperity, these myths entrap and impoverish. Real Men on Top invites readers to see through them and, in so doing, to find new possibilities for living, relating, and becoming human. Sharp, daring, and deeply felt, Real Men on Top is a book for anyone who senses that something is deeply wrong with the way we live and wants to understand how we got here, and where we might begin the work of remaking reality. Robin Dembroff is an Associate Professor of Philosophy at Yale University Caleb Zakarin is CEO and Publisher of the New Books Network. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/politics-and-polemics
In Real Men on Top: How Patriarchy Shapes Our Reality (Oxford University Press, 2026), Robin Dembroff shows us that we don't just live in a patriarchal world. We live in a world that patriarchy taught us to see. Patriarchy is not simply a system where men dominate women, Dembroff argues. It is a deeper reality-shaping force that legitimizes economic exploitation, political injustice, and social cruelty by dividing all of us into the rigid categories of Man, Woman, Animal, and Child. These categories are presented as natural truths, but Dembroff reveals them as man-made myths--ones that construct a reality in which being characterized as Woman, Animal, or Child marks moral degradation. By no coincidence, feminization, dehumanization, and infantilization are the very degradations used to make a man 'less of a man'. But this book is more than critique; it's also a guide to transformation especially for those grappling with what it means to be a man under patriarchy. Patriarchy's myths celebrate the identity Man, but these myths are no friend to most men. Promising strength and superiority, they instead fuel isolation, emotional repression, and relentless pressure to prove oneself while propping up systems that enrich the powerful few. Rather than deliver freedom and prosperity, these myths entrap and impoverish. Real Men on Top invites readers to see through them and, in so doing, to find new possibilities for living, relating, and becoming human. Sharp, daring, and deeply felt, Real Men on Top is a book for anyone who senses that something is deeply wrong with the way we live and wants to understand how we got here, and where we might begin the work of remaking reality. Robin Dembroff is an Associate Professor of Philosophy at Yale University Caleb Zakarin is CEO and Publisher of the New Books Network. Learn more about your ad choices. Visit megaphone.fm/adchoices
Texas standout Brooks Bahr joins the program after a highly‑touted prep career and a church mission. Mitch Harper dives into how he’s feeling physically and mentally as he returns to basketball and looks to make an impact in his first season at BYU.
Molecular hydrogen improves your body's antioxidant defenses instead of directly lowering oxidative stress, helping you recover without blocking muscle adaptation Molecular hydrogen helps you maintain speed and power during repeated sprints, especially in the final, fatigue-heavy stages where performance normally declines Hydrogen supports your cellular energy systems by improving mitochondrial function, allowing your muscles to maintain power under stress Unlike traditional antioxidants, hydrogen targets only the most damaging molecules, preserving the signals your body relies on to build strength and endurance Using hydrogen in short, repeated doses, especially through hydrogen-rich water, strengthens your body's resilience and speeds recovery over time
Matt Williamson, former NFL scout and nationally renowned analyst, breaks down the Pittsburgh Steelers like no one else. Don't miss his insight, every Monday-Friday morning. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Promising oral treatment moves closer for Stargardt patients.
The final hour of Robby & Rexrode continues with Paul Kuharsky of paulkuharsky.com, who brings the latest on the Titans' mandatory mini-camp and the team's performance. Do the Titans have a strong WR core this year? It appears there are five promising WR's who can help contribute to the team. Should the Titans pursue Brendan Sorsby in the NFL supplementary draft?
Promising author, depressing life circumstances for our characters.
Knicks fan Rich basks in Jalen Brunson leading New York to its first NBA championship since 1973 ESPN's Mike Breen tells Rich what it was like to witness the Knicks-Spurs series courtside from the announcers' chair, what the NBA title win means for the city of New York, past players, and more. Rich and the guys react to Team USA's rout of Paraguay in their World Cup opener and what it could foretell about how far the USMNT's could advance in the knockout rounds. Learn more about your ad choices. Visit podcastchoices.com/adchoices
Worship with us live online at ExploreGracePoint.com/church-onlineGracePoint Church2351 Rice Creek RdNew Brighton, MN 55112
Hour 3 -- Another addition of Danny's Double Dips. The guys also dive into the top young stars in Bay Area Sports, and are later joined by Rich Aurilia to break down the Giants epic comeback capped off by a Bryce Eldridge Grand Slam. See omnystudio.com/listener for privacy information.
Hour 3 -- Another addition of Danny's Double Dips. The guys also dive into the top young stars in Bay Area Sports, and are later joined by Rich Aurilia to break down the Giants epic comeback capped off by a Bryce Eldridge Grand Slam. See omnystudio.com/listener for privacy information.
President Donald Trump has changed a lot about American foreign policy – and to many, America itself. But a lot of the issues facing this country were around long before he became president. Ben Rhodes' new book, All We Say: The Battle for American Identity: A History in 15 Speeches, tells the story of this country through speeches by figures like Ben Franklin, Martin Luther King, and yes, Donald Trump. We spoke with Ben about what those speeches reveal about being American, and what Trump's actions in Iran can tell us about his presidency and our country.And in headlines, President Trump continues to whiplash in Iran talks, we have a new pick for the Director of National Intelligence, and Kash Patel prepares the FBI for the World Cup.Show Notes: Check out Ben's book – https://tinyurl.com/pxpr6t8c Call Congress – 202-224-3121 Subscribe to the What A Day Newsletter – https://tinyurl.com/y4y2e9jy What A Day – YouTube – https://www.youtube.com/@whatadaypodcast Follow us on Instagram – https://www.instagram.com/crookedmedia/ For a transcript of this episode, please visit crooked.com/whataday
Funding novel therapeutics isn't just “harder than ever”—the rules have changed entirely. The wild rush of capital into early-stage biotech during 2020–2021 gave way to a drought, making investor priorities sharper and startup hurdles higher than most founders realize.Michael Rome, Managing Director at Foresite Capital, joined the Smart Biotech Scientist Podcast to dissect what's really driving funding decisions today, and what early-stage founders must do to stand out.Key topics discussed:The financial cycle of biotech investment before, during, and after the COVID-19 boom (02:47)Why investors are now focused on clear pathways to approved drugs and how founders should frame their proposals (06:10)The evolving importance of CMC expertise and manufacturing readiness for startups at different stages (07:44)Leadership traits and execution qualities investors appreciate in biotech founders and teams (09:18)Promising scientific and market areas including small molecule oncology, degraders, and heterobifunctional molecules (11:24)Practical advice for founders preparing for fundraising: focusing on unmet medical needs and market analysis (14:55)The impact of recent M&A activity and regulatory challenges at the FDA on the future of biotech investment (16:27)The importance of open communication and collaboration between scientists and investors (18:47)Smart insight: For those preparing their next fundraising push, Michael advised:Start with the end in mind: Outline the unmet need, the clinical and market pathway, and the product vision firstReverse engineer your innovation: Work backwards from market and regulatory needs to inform your technical approach, not the other way around.Frame your business case: Make it obvious to investors how your solution advances value in the ecosystemIf you want to go deeper into the themes from this conversation with Michael Rome—how investors evaluate biotech companies, why CMC and execution matter, and how founders can better frame their science for funding—these episodes are a strong next listen:Episodes 189 - 190: Why Smart Biotech Founders Plan CMC First (While Competitors Burn Cash Later)Episodes 165 - 166: Why Your Funding Pitches Fail Despite Brilliant Science (And How to Fix It)Episodes 183 - 184: From Lab to Market: Secrets to Commercializing Cutting-Edge Biotech Innovations with Chervee HoEpisodes 231 - 232: From IND to BLA: The Biologics CMC Decisions That Determine Regulatory Success with Henri KornmannConnect with Michael Rome: LinkedIn: https://www.linkedin.com/in/michael-rome-5067616b/ Foresite Capital website: www.foresitecapital.comNext: If you enjoyed this episode, please leave a review on Apple Podcasts or your favorite podcast platform. By doing so, we can empower more scientists like you. Stay tuned for more inspiring biotech insights in our next episode.Support the show
The Labour Party is promising cost-of-living relief for public transport users - pledging to cap their fares at no more than $20 a week if elected. National says it's just more irresponsible spending from Labour. Deputy political editor Craig McCulloch reports.
There's a sin you keep promising yourself you'll quit — and you're starting to wonder why you can't. This message walks through Revelation 8 and 9, the seven trumpets, and one uncomfortable truth most of us feel but rarely say out loud: sin doesn't stay a choice forever. At some point you stop choosing it, and it starts choosing you.We tend to read Revelation as a map of the end of the world. But the seventh seal doesn't open onto final destruction — it opens onto the Day of Atonement and a trumpet blast that, to the people who first heard it, meant one thing: a call to come home. The trumpets aren't only about the future. They're a warning about right now — about the thing quietly enslaving you, the way it dresses itself up as harmless, and the freedom that's actually possible when you finally name it. This isn't a timeline. It's an invitation.Support the show
Worship with us live online at ExploreGracePoint.com/church-onlineGracePoint Church2351 Rice Creek RdNew Brighton, MN 55112
We're learning from court transcripts that investigators tested a second male cruise passenger as a potential match to DNA recovered from Anna Kepner's rape kit. Pennsylvania volunteer firefighter confesses he's behind three weekend fires. Promising college football player shot day after his graduation ceremony. Sydney Silvagni reports. See omnystudio.com/listener for privacy information.
A medical breakthrough in the fight against pancreatic cancer is showing promising results after decades of research. The experimental drug, taken once a day, extends patients' lives by slowing the progression of one of the deadliest cancers. Dr. Rachna Shroff, associate director of clinical investigations at the University of Arizona Comprehensive Cancer Center, joins Stephanie Sy for more. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy
In this episode, Crawlspace Media's Tim Pilleri and Lance Reenstierna speak with survivor Jenaé Newell and director Ben Zand about their riveting new docuseries, The Cult of Natureboy. "The Cult of NatureBoy" is a new docuseries examining the dark reality behind online spiritual leader Eligio "NatureBoy" Bishop and his community, Carbon Nation. Promising a liberated "black utopia" through raw living, Bishop lured followers into a manipulative, abusive, and violent sex cult that ended with his life imprisonment. This episode was previously published on Missing on May 21st, 2026. Check out it: https://www.hulu.com/series/ce23eaed-d60d-472f-aa32-294619e7f438. Follow Jenaé Newell: https://www.instagram.com/jenae.alexandrea. Check out Jenaé Newell's book: https://www.amazon.com/Lesson-Learned-Wisdom-Granted-Divine/dp/B0CVF35Q12. Zandland: https://www.zand.land/. Check out Quince: https://quince.com/MISSING. Check out Mint Mobile: mintmobile.com/missing. Main podcast theme by Kevin Macleod. Check out his work at https://incompetech.com/. Additional music by David Williams. See his work at http://williamsflutes.com. Follow Missing: IG: https://www.instagram.com/MissingCSM/. TT: https://www.tiktok.com/@missingcsm. FB: https://www.facebook.com/MissingCSM. X: https://twitter.com/MissingCSM. Spotify: https://open.spotify.com/show/0yRXkJrZC85otfT7oXMcri. Youtube: https://www.youtube.com/missingcsm. Apple: https://podcasts.apple.com/us/podcast/missing/id1006974447. Follow Crawlspace: IG: https://www.instagram.com/Crawlspacepodcast. TT: https://www.tiktok.com/@crawlspacepodcast. FB: https://www.facebook.com/Crawlspacepodcast. X: https://twitter.com/crawlspacepod. Spotify: https://open.spotify.com/show/7iSnqnCf27NODdz0pJ1GvJ. Youtube: https://www.youtube.com/crawlspace. Apple: https://podcasts.apple.com/us/podcast/crawlspace-true-crime-mysteries/id1187326340. Check out our entire network at http://crawlspace-media.com/. Learn more about your ad choices. Visit megaphone.fm/adchoices
In this new episode, Crawlspace Media's Tim Pilleri and Lance Reenstierna speak with survivor Jenaé Newell and director Ben Zand about their riveting new docuseries, The Cult of Natureboy. "The Cult of NatureBoy" is a new docuseries examining the dark reality behind online spiritual leader Eligio "NatureBoy" Bishop and his community, Carbon Nation. Promising a liberated "black utopia" through raw living, Bishop lured followers into a manipulative, abusive, and violent sex cult that ended with his life imprisonment. Check out it: https://www.hulu.com/series/ce23eaed-d60d-472f-aa32-294619e7f438. Follow Jenaé Newell: https://www.instagram.com/jenae.alexandrea. Check out Jenaé Newell's book: https://www.amazon.com/Lesson-Learned-Wisdom-Granted-Divine/dp/B0CVF35Q12. Zandland: https://www.zand.land/. Check out Quince: https://quince.com/MISSING. Check out Mint Mobile: mintmobile.com/missing. Main podcast theme by Kevin Macleod. Check out his work at https://incompetech.com/. Additional music by David Williams. See his work at http://williamsflutes.com. Follow Missing: IG: https://www.instagram.com/MissingCSM/. TT: https://www.tiktok.com/@missingcsm. FB: https://www.facebook.com/MissingCSM. X: https://twitter.com/MissingCSM. Spotify: https://open.spotify.com/show/0yRXkJrZC85otfT7oXMcri. Youtube: https://www.youtube.com/missingcsm. Apple: https://podcasts.apple.com/us/podcast/missing/id1006974447. Follow Crawlspace: IG: https://www.instagram.com/Crawlspacepodcast. TT: https://www.tiktok.com/@crawlspacepodcast. FB: https://www.facebook.com/Crawlspacepodcast. X: https://twitter.com/crawlspacepod. Spotify: https://open.spotify.com/show/7iSnqnCf27NODdz0pJ1GvJ. Youtube: https://www.youtube.com/crawlspace. Apple: https://podcasts.apple.com/us/podcast/crawlspace-true-crime-mysteries/id1187326340. Check out our entire network at http://crawlspace-media.com/. Learn more about your ad choices. Visit megaphone.fm/adchoices
Iran negotiations appear on the verge of collapse as the ceasefire deadline approaches, with U.S. officials preparing to travel for talks even as Iranian leadership signals it may not participate. Outrage is mounting after the IDF confirmed a soldier was responsible for smashing a statue of Jesus in southern Lebanon, prompting condemnation from Prime Minister Netanyahu and Christian leaders. FBI Director Kash Patel files a $250 million defamation lawsuit against The Atlantic, accusing the outlet of knowingly publishing false allegations about his conduct based on anonymous sources. A personalized mRNA vaccine for pancreatic cancer is showing early signs of promise in a small Phase 1 trial. California's governor's race is shifting following Eric Swalwell's exit amid scandal, with new polling showing former HHS Secretary Xavier Becerra gaining ground as a potential contender. Birch Gold: Text MK to 989898 to join Birch Gold's Learn and Earn event by April 30! Supersure Insurance: Simplify your business insurance and get a free coverage report at https://Supersure.com/Megyn Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.