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Episode Highlights With MindyCutting through the myth… can women fast and what we need to do differentlyHow to navigate fasting with a female hormone cycle and why it is so important The three types of women and how each fasts differently There are times when women shouldn't fast and times when it can be a game changerWe have two metabolisms: glucose and ketones and how to use them differently Somewhere 8-12 hours after food we shift to ketones The healing switches that turn on when we fastWhat flex fasting is and how she helps people find what works best for themPerimenopause and menopause specific fasting guidelinesThe cortisol component and how to pay attention to this partCan fasting be brain protective post menopause When to fast and when not to, and the most important meal you eat after fasting The important nutrients to focus on after fasting and the story about leucine Let's stop making beans the enemy! And her take on sardine fasting Supplements she most often recommends and why The one food group that kills our ability to make our own GLP (it might surprise you)Order of food matters, not just the amount and type! Important concerns with GLPs and how to make your own and not lose muscle!Resources MentionedMindy's books - Fast Like a Girl, Age Like a Girl and Eat Like a GirlMindy's YouTube channelStress questionnaireLive like a girl podcastBioptimizersI love and use so many products from them, but I especially love the magnesium (Magnesium Breakthrough) and digestive enzymes (Masszymes). Visit bioptimizers.com/wellnessmama to get the best deal!
In this episode, Dr. David Jockers sits down with fasting expert Ben Azadi, host of the Metabolic Freedom Podcast and author of the book Metabolic Freedom, for a detailed, hour-by-hour walk through exactly what happens inside your body during a 72-hour water fast. You will learn what's really going on at each stage of a fast, from the first 12 hours of digestive rest all the way through ketone production, autophagy, mitochondrial biogenesis, and a dramatic spike in growth hormone, plus why your body targets visceral fat and old, damaged proteins before anything else. Dr. Jockers and Ben also cover how to prepare your body before a long fast, what to eat (and avoid) once you break it, which liquids and supplements actually support a fast, and the specific dopamine and immune system resets that happen at the 48 and 72 hour marks. In This Episode: 00:00 Fasting Supplements Debate 00:27 Podcast Intro and 72 Hour Fast 04:06 12 to 16 Hours Fat Burning 05:51 Ketones and Brain Clarity 08:48 BDNF and Stress Resilience 11:07 Spiritual and Dopamine Reset 13:51 24 Hours Autophagy Begins 16:53 Visceral Fat and Mitochondria 25:12 Growth Hormone and Muscle Loss 29:06 Preparing for a Long Fast 34:20 Push Past Dinner Cravings 35:08 Ghrelin Waves and Herbal Tea 36:43 Deeper Fat Burning Benefits 37:23 Fatty Liver Fuel Explained 38:43 No Such Thing Failed 39:54 Gut Stem Cells and Leaky 44:15 Dopamine Reset at 48 46:38 Immune Reset at 72 47:12 Water Fast vs ProLon 49:29 Discipline and Addiction Break 50:21 What to Drink While 51:59 Supplements Binders and Gut 56:56 Breaking Fast Safely 58:18 Where to Find Jockers 01:00:23 Gratitude Closing Thoughts Paleo Valley grass-fed meat sticks are a clean, kid-friendly snack (or even a meal replacement) with no sugar, additives, or preservatives, and the proper omega-6 to omega-3 ratio you want from grass-fed beef. They come in beef and turkey, with flavors like original, garlic summer sausage, and teriyaki. Go to paleovalley.com/jockers for 15% off your order. If quality protein is always the hardest part of getting dinner on the table, ButcherBox delivers over 100 premium protein options straight to your door, including 100% grass-fed beef, free-range organic chicken, crate-free pork, and wild-caught seafood, fully customizable to fit your routine. Go to butcherbox.com/drjockers to get $20 off your first box, plus your choice of free ground beef for life, or free chicken thighs or top sirloins in every box for a year, with free shipping always. Your skin can absorb more chlorine in a single 10-minute shower than from drinking eight glasses of tap water, and that's exactly what the Aquatru Shower filter is built to stop. It uses advanced four-stage filtration with a copper-zinc KDF blend to neutralize chlorine and chloramine the moment water hits it, protecting your hair, skin, and hair color. Head to aquatrushower.com and use promo code SHNUTRITION for 20% off your Aquatru Shower today. "Visceral fat is literally choking out blood supply from getting into your vital organs." Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio Resources: Visit paleovalley.com/jockers to get 15% off Paleo Valley grass-fed meat sticks and other products Visit butcherbox.com/drjockers to get $20 off your first box, plus a free item choice and free shipping Visit aquatrushower.com and use promo code SHNUTRITION to get 20% off Aquatru Shower Connect with Ben Azadi: Website: https://benazadi.com/ Instagram: https://www.instagram.com/thebenazadi/ YouTube: https://www.youtube.com/@KetoKamp Podcast: https://podcasts.apple.com/us/podcast/the-ben-azadi-show/id1470779784 Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/
In this episode of the Optimal Body Podcast, Doc Jen and Doctor Dom interview nutritionist Thomas DeLauer, who specializes in cognitive nutrition and performance. Thomas shares his journey from corporate healthcare to nutrition advocacy, emphasizing how nutrition and diet impact brain function and mental clarity. He highlights key foods like dark berries, MCT oil, and eggs for cognitive support, discusses metabolic flexibility, and introduces the concept of "energy flux" for improving metabolism. Thomas also offers practical strategies for sustainable lifestyle changes, including managing willpower and optimizing meal timing for peak mental and physical performance. Needed Discount: Jen trusted Needed Supplements for fertility, pregnancy, and beyond! Support men and women's health and nutrition with vitamins, Omega-3, and more. Used by 6,000+ pros. Use code OPTIMAL for 20% off at checkout! Thomas's Resources: Thomas on IG Thomas on YT Thomas's Website Thomas on FB We Think You'll Love: FREE week of Jen Heath Jen's Instagram Dom's Instagram YouTube Channel For full show notes and resources visit https://jen.health/podcast/473 What You'll Learn: 2:05 What is Cognitive Nutrition? 8:09 Optimizing Energy and Brainpower 11:09 Foods for Mental Clarity 15:06 Fasting and Ketones for Brain Function 21:52 Understanding Metabolism 28:52 Improving Metabolic Health 32:08 Dieting Without Crashing Your Metabolism 35:20 Intuitive Eating and Whole Foods 38:07 The Importance of Protein and Fiber 42:33 Maintaining Willpower Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Send us Fan MailToday we're releasing a new episode from a brand new series called the Boundless Body Radio Heritage Series! I wanted to do something extra special to celebrate 1,000 podcast episodes recorded here at Boundless Body Radio, a milestone that we hit on June 24, 2026!These episodes are actually not new, although they might be new to you! When we first got started back in October, 2020, I was so fortunate that so many incredible people said "YES" to being hosted on the show, however, we didn't have very many listeners at the time!Today, we get thousands of downloads every single month, and are usually included in the top 150 Fitness and Nutrition Podcasts on the Apple Podcast charts!To honor our amazing guests, I will be selecting one of those original episodes and posting them here on for this special series!As I was going through these episodes again, I remembered how valuable these conversations actually were. it was really striking how much the information these experts have shared has born out to be even more accurate several years later.The audio quality of a show was not as good back then as it is now, but I still really hope you enjoy these episodes, and find them relevant and helpful to you today!Cheers, thanks as always for listening, and I really hope you enjoy this episode of the Boundless Body Radio Heritage Series!Dr. Thomas Seyfried is a returning guest on our show! Be sure to check out his first appearance on Boundless Body Radio on episode 60, which one of the most fascinating discussions we've ever had, all about cancer as a metabolic disease! He was also hosted on episode 363 of our podcast.Thomas N. Seyfried received his Ph.D. in Genetics and Biochemistry from the University of Illinois, Urbana, in 1976. He was a Postdoctoral Fellow in the Department of Neurology at the Yale University School of Medicine and then served on the faculty as an Assistant Professor in Neurology. Other awards and honors have come from such diverse organizations as the American Oil Chemists Society, the National Institutes of Health, The American Society for Neurochemistry, the Ketogenic Diet Special Interest Group of the American Epilepsy Society, the Academy of Comprehensive and Complementary Medicine, and the American College of Nutrition.Dr. Seyfried has over 150 peer-reviewed publications and is the author of the book, Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer (Wiley, 1st ed., 2012).Find Dr. Seyfried at-https://foundationformetaboliccancertherapies.com/Movie, coming soon- CANCERREVOLUTION: A Cancer Science Documentary with Dr. Seyfried and former podcast guest Travis Christofferson.Find Boundless Body at-myboundlessbody.comFind Boundless Body at-myboundlessbody.comBook a session with us here!
Intermittent fasting and periodic prolonged fasting may be among the most beneficial things you can do for your health. Discover the benefits of fasting, the best intermittent fasting patterns, how to break a fast, and what happens to your body when you fast.0:00 Prolonged fasting 1:35 Intermittent fasting2:44 Benefits of fasting3:35 Ketones and fat burning4:17 Growth hormone 4:30 Extended fasting benefits 4:55 16:8 fasting and other fasting patterns5:27 Spermidine 5:52 Refeeding after a fast6:07 Fasting and stem cells6:30 How to break a fast6:54 Meal timing and insulin resistance 8:26 Fasting and menstrual cycles 9:02 Fasting and menopause 9:39 Fasting and PCOS 10:29 Prolonged fasting and testosterone11:17 Should I exercise while fasting?
Daniel Rowland and Mikael are back for another research roundup with four recent studies. What blood biomarkers do and do not tell you about training load in elite triathletes, why two athletes with the same VO2max can have very different thresholds, what actually predicts running injuries in a cohort of 5,200 runners, and whether supersets deliver the same strength gains in a third less gym time. HIGHLIGHTS AND KEY TOPICS: VLaMax (maximal glycolytic flux) and metabolic thresholds: the first evidence in real athletes that at a given VO2max, a higher glycolytic rate means a lower threshold power. How VLaMax is measured, why sprint power on its own tells you little to nothing, and whether you can and should measure it and base training decisions off it. How much running is too much: in 5,205 runners tracked over 18 months, a single run 10 to 30% longer than the longest run of the previous 30 days came with a 64% higher injury risk, and bigger jumps than that led to injury risk increasing by well over 100%. Why the acute:chronic workload ratio and the classic weekly 10% rule showed little or no relationship with injury, and why you should never use the performance management chart for controlling running load. Practical long run progression for a marathon or an Ironman, and the one TrainingPeaks chart Mikael looks at more than any other. Four seasons of blood urea and creatine kinase in 20 elite (some world class) triathletes: urea tracks training load, CK does not, and a single reading against a reference range means almost nothing. Why the ratio of objective to subjective training load may be the most useful signal a coach has, and a heuristic for using it in practice. Supersets versus traditional sets: the same strength, hypertrophy, power and body composition gains in 36% less time, 44 minutes per session against 69, and how to apply that to a triathlete's lower body dominant strength programme. SHOWNOTES, LINKS, RESOURCES AND RELATED EPISODES: Follow Daniel Rowland and Endurance: Ideas + Implementation on his website, Substack and Instagram. The shownotes for today's episode can be found here. The full podcast episode archives (including category filters) can be found here. New Research on Torque Training, Ketones, Carb Loading and Pacing | Daniel Rowland | EP#698 Is VO2max more important than lactate threshold? | Research roundup | EP#705 Is Optimised Workout Design Pointless (and Time in Zone What Really Matters)? | Q&A | EP#708 Maximal glycolytic flux modulates metabolic thresholds independent of maximal oxygen uptake - Meixner et al. 2026 How much running is too much? Identifying high-risk running sessions in a 5200-person cohort study - Schuster Brandt Frandsen et al. 2025 Dose-response to endurance training: a longitudinal study of training load and biomarkers in elite triathletes - Cejuela et al. 2026 Less time, same gains: Comparison of superset vs traditional set training on muscular adaptations - Burke et al. 2024 SPONSORS: Precision Fuel & Hydration produce our favourite gels, sports drinks, and electrolyte and carbohydrate products here at That Triathlon Show and Scientific Triathlon. Use the free Fuel & Hydration Planner to get a personalised plan for your carbohydrate, sodium and fluid intake in your next event, and get 15% off your first 2026 order by using the code TTS2026 at checkout. Rouvy is hands down the most complete indoor cycling platform for triathletes. Among their thousands of beautiful bike courses from all around the world, all filmed in stunning quality, they have over 75 IRONMAN and IRONMAN 70.3 race courses plus 20+ Challenge Family courses, so you can pre-ride your race from home. Real gradients, real visuals, and real feel! Head to rouvy.com and use the code TTS to get your first month free on top of a 7-day free trial. Effortless Swimming produce the best swim goggles for triathletes and open water swimmers. Their NanoClear anti-fog lenses give you clear, fog-free vision that lasts and doesn't wear off. Don't let foggy or leaky goggles ruin another swim. Go to shop.effortlessswimming.com and use the code TTS15 to get 15% off your goggles, and get a free two-month Effortless Swimming course membership.LEARN MORE ABOUT SCIENTIFIC TRIATHLON: The Scientific Triathlon website is the home of That Triathlon Show and everything else that we doContact us through our contact form or email me directly (note - email/contact form messages get responded to much more quickly than Instagram DMs)Subscribe to our NewsletterFollow us on InstagramLearn more about our coaching, training plans, and training camps. We have something to offer for everybody from beginners to professionals.HOW CAN I SUPPORT THAT TRIATHLON SHOW (FOR FREE)? I really appreciate you reading this and considering helping the show! If you love the show and want to support it to help ensure it sticks around, there are a few very simple things you can do, at no cost other than a minute of your time. Subscribe to the podcast in your podcast app to automatically get all new episodes as they are released.Tell your friends, internet and social media friends, acquaintances and triathlon frenemies about the podcast. Word of mouth is the best way to grow the podcast by far!Rate and review the podcast (ideally five stars of course!) in your podcast app of choice (Spotify and Apple Podcasts are the biggest and most important ones).Share episodes online and on social media. Share your favourite episodes in your Instagram stories, start a discussion about interesting episodes on forums, reference them in your blog or Substack. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
In this episode of the Health Optimization Medicine Podcast, Dr. Scott Sherr sits down with Dr. Dominic D'Agostino, the premier researcher in ketogenic metabolic therapies. Moving past the mainstream fads of keto ice cream and internet trends, they break down how exogenous ketones actually impact cellular energy, cardiovascular health, and environmental stress. From the liver toxicity associated with certain high-dose ketone esters to the hidden vasodilatory superpowers of L-BHB, this discussion separates the biohacking hype from the physiological reality of ketone supplementation. Join us as we delve into: Fad vs. Science: Why serious researchers use the term Ketone Metabolic Therapy instead of Ketogenic Diet, and why peer-reviewed science is growing exponentially despite Google trends. The Metformin VO2 Max Penalty: Exploring recent data showing metformin can blunt VO2 max adaptations to exercise by 50% and acts as a weak mitochondrial toxin. Mitochondrial Hydraulic Efficiency: How ketones physically tighten electron flow in the mitochondria, reducing superoxide (ROS) production and enhancing endogenous antioxidant capacity. The Danger of 1,3-Butanediol: Why relying on high doses of certain ketone esters and diols can trigger dizziness, liver abnormalities, and dependence, and how to formulate them safely. The L-BHB Advantage: Why the lesser-known L-enantiomer of BHB acts as a potent vasodilator, significantly increasing cardiac output and brain blood flow through adenosine signaling. Performance vs. Recovery: Why exogenous ketones might underwhelm a healthy athlete looking for a power boost, but shine in extreme stress environments like hypoxia, hyperoxia, and recovery. This episode is for you if: You want to know the difference between a nutritional ketogenic diet and simply taking exogenous ketone supplements. You are concerned about the side effects, liver stress, and acidic load of pushing your blood ketone levels too high. You are interested in the synergistic effects of Hyperbaric Oxygen Therapy (HBOT) combined with ketone therapies for traumatic brain injury and mitigating oxygen toxicity. You can also find this episode on… YouTube: https://youtu.be/sU-ZNinqqgg Find more from Dr. Dominic D'Agostino: Website: https://ketonutrition.org/ Metabolic Health Initiative: https://www.metabolicinitiative.com/ Instagram: https://www.instagram.com/dominic.dagostino.kt/ LinkedIn: https://www.linkedin.com/in/dominic-d-agostino-156014b/ Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ HOMeHOPe Conference 2026: https://homehope.org/homehope-conference-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products
When did you last actually let yourself feel hungry? Not the "due for a snack" kind. Properly, deliberately hungry, on purpose. If you can't remember, you're not alone. Now imagine using that discomfort as a lever instead of avoiding it.Every reflexive snack, every meeting that runs straight into the next, every bite you take before your body even asks for it keeps you running on one setting. You never give your body the signal to switch fuel sources, sharpen your focus, or clean house at a cellular level. The fog, the afternoon slump, the stubborn weight that won't shift: that's the bill for never stopping.Dr Tom Buckley has spent more than 22 years reading the bloodwork of Performance Intelligence's executive clients, translating what's happening inside hundreds of high performers into how they eat, train, and lead. He's back on the podcast to explain what fasting actually does inside your body, why the meal you were told never to skip has a cereal company to thank for that reputation, and how two nights a week without dinner might be the highest-leverage habit in your week.You could keep running on constant fuel and wonder why your energy never settles. Or you could learn to use hunger as a lever instead of an enemy.03:35 The fat that's easiest to shift, and where it sits 05:41 Ghrelin, leptin and the people who never feel full 09:03 Three fuels, one easy habit: why carbohydrate wins by default 10:27 Metabolic flexibility: the skill Western living has trained out of us 16:08 The story that's driven Dr Tom for 35 years 21:47 What fasting switches off first 22:47 Ketones: the fuel that skips the insulin queue 25:13 Fasting and the new GLP-1 drugs are chasing the same biology 27:33 The shortcut risk: trading discipline for a jab 28:17 What decades of fasting research actually agree on 31:16 The benefits nobody puts on the label 33:21 Andrew's own Tuesday and Thursday fast, and why it finally clicked 36:01 The worst thing we do as humans, and the second worst thing 41:20 Autophagy: the cellular housekeeping everyone's talking about 44:22 Marvellous mitochondria, and why the name always gets a rerecord 45:00 The 18:6 protocol Dr Tom and Andrew actually live by 46:37 Why 6pm to midday captures most of the benefit 48:49 The client who fasted every day and undid his own progress 50:06 Why Dr Tom says don't pull this lever before your late 30s 51:39 David Sinclair's one-meal-a-day experiment 53:06 The 24-hour fast Dr Tom takes on international flights 54:50 Why women need a different rulebook entirely 58:29 Dirty fasting and dirty keto: the shortcut that costs you later 60:47 Dr Tom's cliff notes for the time-poor listenerWatch on Youtube: https://youtu.be/iiDAwpx78yoThe resource Dr Tom referenced for women's fasting protocols: Fast Like a Girl by Dr Mindy Pelz: https://fastlikeagirl.com/You can find Dr Tom at his LinkedIn: https://www.linkedin.com/in/tom-buckley-06a76b98/Listen to Dr Tom and Andrew talk GLP-1s: https://performanceintelligence.com/the-science-of-ozempic-and-what-happens-after-you-stop-dr-tom-buckley/
Join us for a live Q&A with Dr. Ben Bikman here.For the 100th episode of The Metabolic Link, Ben Bikman, PhD, professor of cell biology and physiology at Brigham Young University and author of Why We Get Sick, returns for a milestone conversation with co-hosts Dominic D'Agostino, PhD, and Victoria Field. Together, they examine what clinicians are measuring, what conventional approaches may be missing, and how the science of metabolic health continues to evolve.Bikman argues that the clinical picture of metabolic health remains glucose-centric and lipid-heavy while the earliest signal, elevated insulin, goes unmeasured. He explains why women stay insulin sensitive at far higher body fat than men and what menopause takes away, why visceral fat is misunderstood, and how a fatty liver can be miscounted as lean mass on a DEXA scan. That last point is why he now says he was wrong about GLP-1 drugs, and why he thinks they should be prescribed as something other than weight loss medication.Questions Answered in This Episode:• Why does standard bloodwork detect metabolic dysfunction so late?• Why are women more insulin sensitive than men at the same or higher body fat?• What actually changes metabolically during menopause?• Is visceral fat inherently dangerous, or is something else going on?• Why did Dr. Bikman change his position on GLP-1 medications?• Should GLP-1 drugs be prescribed as weight loss drugs at all?This milestone episode offers a rigorous, physiology-first look at where metabolic science stands today, and what researchers and clinicians may need to examine next.Thank you for listening, watching, sharing these conversations, and helping us reach 100 episodes. We're incredibly grateful to have you as part of this community.Special thanks to the sponsors of this episode:Genova Connect: Get 15% off any Genova Connect test kit with code METABOLICLINK here.Cowboy Colostrum: Get up to 25% off with code METABOLIC here.iRestore: Get a special discount on the iRestore Illumina face mask with code LINK here.More LinksDr. Ben Bikman's website: benbikman.comInsulin IQ: insuliniq.comYouTube: youtube.com/@benbikmanInstagram: @benbikmanphdFeatured study: White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's DiseaseIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: InstagramFacebookYouTubeLinkedInPlease keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
Send us Fan MailBen Azadi is a returning guest on our show! Be sure to check out his first appearances on episodes 290 and 798 of Boundless Body Radio!Ben Azadi, FDN-P, is a leading authority on metabolic health, international keynote speaker, and New York Times bestselling author. After facing his own health challenges, Ben transformed his life in 2008—losing 80 pounds and stepping into metabolic freedom. That turning point sparked a global mission: to help 1 billion people break free from physical and mental obesity through education, not medication.With 18+ years in the health and wellness space, Ben is now leading a bold 10-year initiative to naturally reverse type 2 diabetes in 1 million people. Through his work, Ben has reached millions worldwide and personally coached thousands to reclaim their health.His following includes an audience of nearly 3M+ on digital platforms, more than 1M YouTube subscribers with over 100M views, and his top-ranked podcast, The Ben Azadi Show, which has surpassed 100 million downloads.Ben is the author of several best-selling books, including Metabolic Freedom: A 30-Day Guide to Restore Your Metabolism, Heal Hormones & Burn Fat. His latest book is a revised addition of Keto Flex Revised: The Advanced Guide to Metabolic Flexibility, Fat Burning, and Hormone Health for Every Body at Every Stage.Find Ben at-www.benazadi.comketoflexbook.comIG- @thebenazadi Find Boundless Body at-myboundlessbody.comBook a session with us here!
Send us Fan MailBen Azadi is a returning guest on our show! Be sure to check out his first appearances on episodes 290 and 798 of Boundless Body Radio!Ben Azadi, FDN-P, is a leading authority on metabolic health, international keynote speaker, and New York Times bestselling author. After facing his own health challenges, Ben transformed his life in 2008—losing 80 pounds and stepping into metabolic freedom. That turning point sparked a global mission: to help 1 billion people break free from physical and mental obesity through education, not medication.With 18+ years in the health and wellness space, Ben is now leading a bold 10-year initiative to naturally reverse type 2 diabetes in 1 million people. Through his work, Ben has reached millions worldwide and personally coached thousands to reclaim their health.His following includes an audience of nearly 3M+ on digital platforms, more than 1M YouTube subscribers with over 100M views, and his top-ranked podcast, The Ben Azadi Show, which has surpassed 100 million downloads.Ben is the author of several best-selling books, including Metabolic Freedom: A 30-Day Guide to Restore Your Metabolism, Heal Hormones & Burn Fat. His latest book is a revised addition of Keto Flex Revised: The Advanced Guide to Metabolic Flexibility, Fat Burning, and Hormone Health for Every Body at Every Stage.Find Ben at-www.benazadi.comketoflexbook.comIG- @thebenazadi Find Boundless Body at-myboundlessbody.comBook a session with us here!
In this edition of The Random Show, Tim Ferriss and Kevin Rose reunite over tequila to talk Zen retreats, learning to rock climb at (almost) 50, mortality and grief, why you should stop saying "one day," AI predictions , and much more. Please enjoy!This episode is brought to you by:Incogni, which removes your personal data from the web, helping shield you from fraud, scams, and identity theft: Incogni.com/Tim (use code TIM at checkout and get 60% off an annual plan)Wealthfront high-yield cash account: Wealthfront.com/Tim New clients get 3.30% base APY from program banks + additional 0.75% boost for 3 months on your uninvested cash (max $150k balance). Terms and conditions apply. The Cash Account offered by Wealthfront Brokerage LLC (“WFB”) member FINRA/SIPC, not a bank. The base APY as of 1/30/26 is representative, can change, and requires no minimum. Tim Ferriss, a non-client, receives compensation from WFB for advertising and holds a non-controlling equity interest in the corporate parent of WFB, which creates a conflict of interest. Individual experiences and outcomes will differ. Instant withdrawals may be limited by your receiving firm and other factors. Investment advisory services provided by Wealthfront Advisers LLC, an SEC-registered investment adviser. Securities investments: not bank deposits, not bank-guaranteed or FDIC-insured, and may lose value.Timestamps[00:00:00] Start.[00:00:24] A tequila toast, and getting "taxed" by alcohol as you age.[00:02:18] Toaster at 15: a late-night health scare.[00:06:01] Losing Om Malik, and finding out on retreat.[00:08:03] Matt Mullenweg, Antarctica, and gratitude.[00:09:34] Coming to terms with our limited time on Earth.[00:14:37] Five days of silence and the koan "Mu."[00:15:20] Kevin's micro-insight and a plug for The Way.[00:27:25] Rock climbing after 40, and a Yosemite goal.[00:29:18] Michael Eckert and finger-strength training.[00:30:40] The Nug, Abrahangs, and a travel training kit.[00:32:57] Free Solo and climbing with a fear of heights.[00:37:53] The Blade Itself, and a friend lost in a plane crash.[00:39:19] A2 protein and Pioneer Pastures.[00:40:34] Maui Nui venison and the nitrate question.[00:43:48] deltaG ketones: what they are and the catch.[00:45:42] Ketones, dementia, and verbal fluidity.[00:46:29] Pre-grieving a parent's decline.[00:48:33] Training not to die: the one bike I can stand and the Norwegian 4×4.[00:51:10] Something beats nothing: saunas, treadmills, and Duolingo chess.[00:53:04] The MM120 anxiety study — and a small-world surprise.[00:56:17] Psilocybin, LSD, and dementia case reports.[01:01:28] Neutonic toothpicks and Kevin's AI-powered home.[01:06:12] Spooky AI personalization and investment autopsies.[01:17:38] Values cards, contractual bonds, and dark information.[01:23:25] 360 reviews and child-rearing.[01:24:54] Wispr Flow, Shokz, and my recording rig.[01:29:32] The "big three" and where AI goes next.[01:44:40] Let your winners run; buy the company, not the product.[01:51:08] Digg's relaunch, 5-Bullet Friday, and parting thoughts.*DISCLAIMER FROM TIM FERRISS: I am not an investment adviser. Nor is Kevin Rose. All opinions are mine alone. Or his. There are risks involved in placing any investment in securities or in Bitcoin or in cryptocurrencies or in anything. None of the information presented herein is intended to form the basis of any offer or recommendation or have any regard to the investment objectives, financial situation, or needs of any specific person, and that includes you, my dear listener or reader. Everything you're going to hear is for informational entertainment purposes only.*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
He carried two copies of ApoE4, the highest genetic risk factor for Alzheimer's disease, went through medical school knowing exactly what his LDL of 700 meant, decided the experts were wrong, and then published the case report to prove it. In this episode, Louisa sits down with Dr. Nick Norwitz, PhD researcher and metabolic scientist, for one of the most scientifically dense conversations on brain health, cholesterol biology, and Alzheimer's prevention ever recorded on this show. They cover why the phospholipid form of DHA reaches the brain more effectively than standard fish oil, how ApoE4 carriers burn through omega-3s differently and what to do about it, the lithium orotate data that sold out supplement shelves worldwide, and why GSK-3 beta, the enzyme that phosphorylates tau, may be the most under appreciated target in Alzheimer's research today. Then Dr. Nick Norwitz lays out the case that challenges the "LDL is always the enemy" consensus: why metabolically healthy individuals may not benefit from aggressive lipid-lowering therapy, what his viral coronary CT angiogram showed after seven years of 700+ cholesterol, why the EZPAVE trial headlines don't hold up under scrutiny, and what GLP-1s are doing inside the brain completely independent of weight loss. You'll also hear about the sardine diet experiment, the omega-3 thermogenesis connection, ketones as misfolded protein clearance agents, creatine for depression, retatrutide and PCSK9, BPC-157 risks, and what Dr. Nick Norwitz believes is coming in Alzheimer's gene therapy within the next decade. *Reduce your risk of Alzheimer's with my science-backed protocol for women 30+:*https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ *TOPICS DISCUSSED*(00:00:00) Intro: The ApoE4 Paradox and the Case Report That Broke the Internet (00:00:57) Why Standard Omega-3 Supplements Fail and What to Take Instead (00:05:13) DHA and the Phospholipid Carrier: How It Crosses the Blood-Brain Barrier (00:10:19) ApoE4 Explained: Risk, Genetics, and Why Nick Is Optimistic (00:17:38) Why ApoE4 Carriers Burn Through DHA Faster and Need More (00:20:31) Women, Omega-3s, Menopause, and Brain Insulin Resistance (00:21:41) Statins, Sex Differences, and the DHA-Blood Sugar Connection (00:26:01) Statins and Dementia: What the Data Actually Say (00:32:24) Tau, GSK-3 Beta, Lithium Orotate, and Targeting Alzheimer's Pathology (00:42:19) The Glymphatic System, 40Hz Devices, and Sleep as Brain Clearance (00:45:21) Gene Editing, Prime Editing, and the Future of ApoE4 Therapy (00:49:33) Nick's Case Report: 700 LDL, Zero Plaque, and Seven Years of Data (00:55:10) The EZPAVE Trial: Why the Headlines Don't Hold Up (01:00:33) KetoneIQ: Ketones for Brain Energy and Focus (01:01:29) Cheers Health: Supporting Liver Function and Cognitive Recovery (01:03:54) If Not LDL, What Causes Heart Disease in Metabolically Healthy People? (01:12:05) The Oreo Experiment and the Sardine Diet: Self-Experiments in Metabolism (01:19:10) Ketones, Women's Brains, and Clearing Misfolded Proteins (01:21:08) The Full Brain Health Protocol: Omega-3s, Creatine, NAD, Lithium, and More (01:24:01) GLP-1s for the Brain: Independent of Weight, Targeting Amyloid and Tau (01:25:28) Peptides: BPC-157 Risks, Retatrutide, MOTS-c, and What's Worth Watching (01:29:02) Why Nick Is Controversial And Why He Doesn't Mind _______ *Thank you to our sponsors*Fenix Health Science: fenixhealthscience.com Use code NEUROEXPPulsetto: https://pulsetto.tech/pages/NEURO or use Code NEURO for some off your orderFunction Health: https://www.functionhealth.com/louisanicolaBASED Bodyworks: https://basedbodyworks.com/ and use code NEURO for 20% offKetoneIQ: https://ketone.com/NEURO for 30% OFFCheers Health: https://CheersHealth.com/NEURO or use code NEURO for 20% off _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention.If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0Instagram: https://www.instagram.com/louisanicola_/Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
He carried two copies of ApoE4, the highest genetic risk factor for Alzheimer's disease, went through medical school knowing exactly what his LDL of 700 meant, decided the experts were wrong, and then published the case report to prove it. In this episode, Louisa sits down with Dr. Nick Norwitz, PhD researcher and metabolic scientist, for one of the most scientifically dense conversations on brain health, cholesterol biology, and Alzheimer's prevention ever recorded on this show. They cover why the phospholipid form of DHA reaches the brain more effectively than standard fish oil, how ApoE4 carriers burn through omega-3s differently and what to do about it, the lithium orotate data that sold out supplement shelves worldwide, and why GSK-3 beta, the enzyme that phosphorylates tau, may be the most under appreciated target in Alzheimer's research today. Then Nick lays out the case that challenges the "LDL is always the enemy" consensus: why metabolically healthy individuals may not benefit from aggressive lipid-lowering therapy, what his viral coronary CT angiogram showed after seven years of 700+ cholesterol, why the EZPAVE trial headlines don't hold up under scrutiny, and what GLP-1s are doing inside the brain completely independent of weight loss. You'll also hear about the sardine diet experiment, the omega-3 thermogenesis connection, ketones as misfolded protein clearance agents, creatine for depression, retatrutide and PCSK9, BPC-157 risks, and what Nick believes is coming in Alzheimer's gene therapy within the next decade. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+:https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: The ApoE4 Paradox and the Case Report That Broke the Internet 00:57 Why Standard Omega-3 Supplements Fail and What to Take Instead 05:13 DHA and the Phospholipid Carrier: How It Crosses the Blood-Brain Barrier 10:19 ApoE4 Explained: Risk, Genetics, and Why Nick Is Optimistic 17:38 Why ApoE4 Carriers Burn Through DHA Faster and Need More 20:31 Women, Omega-3s, Menopause, and Brain Insulin Resistance 21:41 Statins, Sex Differences, and the DHA-Blood Sugar Connection 26:01 Statins and Dementia: What the Data Actually Say 32:24 Tau, GSK-3 Beta, Lithium Orotate, and Targeting Alzheimer's Pathology 42:19 The Glymphatic System, 40Hz Devices, and Sleep as Brain Clearance 45:21 Gene Editing, Prime Editing, and the Future of ApoE4 Therapy 49:33 Nick's Case Report: 700 LDL, Zero Plaque, and Seven Years of Data 55:10 The EZPAVE Trial: Why the Headlines Don't Hold Up 01:00:33 KetoneIQ: Ketones for Brain Energy and Focus 01:01:29 Cheers Health: Supporting Liver Function and Cognitive Recovery 01:03:54 If Not LDL, What Causes Heart Disease in Metabolically Healthy People? 01:12:05 The Oreo Experiment and the Sardine Diet: Self-Experiments in Metabolism 01:19:10 Ketones, Women's Brains, and Clearing Misfolded Proteins 01:21:08 The Full Brain Health Protocol: Omega-3s, Creatine, NAD, Lithium, and More 01:24:01 GLP-1s for the Brain: Independent of Weight, Targeting Amyloid and Tau 01:25:28 Peptides: BPC-157 Risks, Retatrutide, MOTS-c, and What's Worth Watching 01:29:02 Why Nick Is Controversial And Why He Doesn't Mind _______ Thank you to our sponsors Fenix Health Science: fenixhealthscience.com Use code NEUROEXP Pulsetto: https://pulsetto.tech/pages/NEURO or use Code NEURO for some off your order Function Health: https://www.functionhealth.com/louisanicola BASED Bodyworks: https://basedbodyworks.com/ and use code NEURO for 20% off KetoneIQ: https://ketone.com/NEURO for 30% OFF Cheers Health: https://CheersHealth.com/NEURO or use code NEURO for 20% off _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
Everyone seems to be chasing the next breakthrough: the newest biohack, recovery tool, supplement, wellness trend, luxury gym membership, or productivity hack. Yet the people who appear happiest often have something much simpler—a clear purpose, meaningful relationships, a strong body, and a life built around things they genuinely enjoy. Kenny Santucci returns for a third appearance, but this time the format is different. This is two longtime friends sitting down for an unfiltered conversation about the current state of fitness culture, gym innovation, entrepreneurship, wellness trends, relationships, happiness, and why so many people overcomplicate what it means to live well. From cold plunges and coffee obsessions to business growth, purpose, dating, community, and finding peace in your forties, this episode is a reminder that the best life isn't always the most optimized—it's the one you actually enjoy living. Follow Kenny @kennysantucci Follow Chase @chase_chewning ----- 00:00 – Kenny is BACK 02:00 – The future of gym equipment and fitness innovation 08:25 – Why experience matters more than products 13:00 – Luxury gyms, wellness clubs and what people really pay for 18:30 – Ketones, performance and chasing the next wellness trend 21:40 – Why most people live somewhere in the middle 25:00 – Metal music, Enya and finding balance 26:20 – Othership, mushrooms and wellness culture 29:00 – Open-mindedness versus blind judgment 30:30 – Building teams and scaling businesses 37:40 – Who takes care of the entrepreneur? 39:00 – Kenny's definition of the perfect day 41:40 – Coffee, cigars and simple pleasures 47:00 – Why happiness isn't more stuff 54:45 – Relationships, freedom and staying true to yourself 57:00 – Marriage, family and timing 01:03:00 – Arnold Schwarzenegger and breaking the rules 01:08:00 – Why Chase stopped attending wellness events 01:11:00 – Getting older and caring less what people think 01:12:00 – Purpose, fulfillment and avoiding resentment 01:14:00 – The reality of aging and why fitness matters 01:16:30 – Kenny's definition of Ever Forward ----- Episode Resources: Energy Bits - 20% off with code EVERFORWARD KETONE IQ - 30 % off brain fuel LMNT - free sample pack 38terra - 33% off gut health Watch and subscrbe on YouTube
Have you heard of ketones, but not really sure what it means? Do we make them ourselves or do we take them as a supplement? And wonder if this is just another wellness trend? We cover: Why your brain energy drops in perimenopause even before your period stops, and what estrogen has to do with it What ketones actually are and why they're so much more than just a fasting byproduct How to get the benefits of ketosis without going low carb or skipping meals What to look for on a ketone supplement label so you're not wasting money on something that barely works The surprising ways ketones may help with brain fog, joint pain, migraines, and workout recovery Past episode NAD: Key to Longevity or Dangerous Shortcut? https://podcasts.apple.com/us/podcast/nad-key-to-longevity-or-dangerous-shortcut-uncovering/id1531105768?i=1000725528296 Contact Courtney Van Bussum: Website: https://longevitylaunch.com/about-us Give thanks to our sponsors: Try Vitali skincare. 20% off with code ZORA here - https://vitaliskincare.com Get Primeadine spermidine by Oxford Healthspan. 15% discount with code ZORA here - https://www.oxfordhealthspan.com/ZORA Get Mitopure Urolithin A by Timeline. 20% discount with code ZORA at https://timeline.com/zora Try MitoQ for optimal mitochondrial health. Code ZORA for 20% off https://mitoq.com/zora Join the Hack My Age community on: YouTube: https://youtube.com/@hackmyage Facebook Page: @Hack My Age Facebook Group: @Biohacking Menopause Biohacking Menopause Private Women's Only Support Group: https://hackmyage.com/biohacking-menopause-membership/ Instagram: @HackMyAge Website: HackMyAge.com For partnership inquiries: https://www.category3.ca/ Some episodes of Hack My Age are supported by partners whose products or services may be discussed during the show. The host may receive compensation or earn a minor commission if you purchase through affiliate links at no extra cost to you. All opinions shared are those of the host and guests, based on personal experience and research, and do not necessarily represent the views of any sponsor. Sponsorships do not imply medical endorsement or approval by any healthcare provider featured on this podcast.
We removed all the cutlery from our house before this great episode! The main science discussion was on a new study looking at reproducibility of adaptations in individual athletes. The relatively surprising finding is that there was no significant correlation in how the same athlete responds to the same intervention across time. We discuss what that means for training science. The word “holistic” is coming in hot.We also talked about a new study on post-exercise ketones, finding a 15% increase in natural EPO levels. Even knowing that, we aren't recommending ketones to many athletes we coach. What's going on? The disclaimers will blot out the sun.And this one was full of fun topics! Other topics: when good butter knives go bad, Tom Evans doing the coolest downhill training on the treadmill, new trail supershoe data, a study on carb intake and bone health, and how collagen may impact bone health for female athletes. Plus questions on breathing, uphill treadmill miles, breakups, programming workouts, coaching communication, and more.We love you all! HUZZAH!-David and MeganClick "Get 40% Off" button for 40% off at The Feed here: thefeed.com/swapBuy Janji's amazing gear: https://janji.com (code "SWAP")20% flash deal for the Wahoo Kickr Run treadmill on Wednesday: https://www.wahoofitness.com/devices/running/treadmills/kickr-run-buy (code “SWAP”)For training plans, weekly bonus podcasts, heart rate zones, articles, and videos: patreon.com/swap
Sponsored By:→ Neuro | Go to https://getneuro.com and use code ONEDAY at checkout for 15% OFF your entire order.DescriptionHe licensed technology from Oxford, sold it to Navy SEALs and the US Department of Defense, brought the price from $30 a shot to $5, and is now stocking shelves at Chevron and Equinox. This is what it looks like to create a new category from scratch and refuse to stop.Jon Bier sits down with Michael Brandt — Stanford CS grad, 2:35 marathoner, and co-founder and CEO of Ketone-IQ — for one of the most genuinely nerdy, genuinely exciting conversations about building a brand that didn't exist before. Jon helped launch Ketone-IQ early on and didn't invest. He'll tell you that himself. This is the conversation where he probably fully processes that decision.Ketones aren't a trend. They're a nutritional primitive — a new macronutrient. The kind of thing you can't speed-run. And Michael Brandt is the rare founder who built his entire business philosophy around that truth.The category is coming. They just got here first.In this episode:• Why creating a new category is a decade-long bet — and why that's exactly the right bet if you want to build something fundamental instead of fast• How Ketone-IQ went from a $6M DoD contract and $30-a-shot margins to nationwide grocery stores and a near-half-billion-dollar valuation• What Jon and Michael actually talk about when they talk about celebrity deals, brand equity, and why the brands nobody can name are the real cautionary taleFind Michael & Ketone-IQ:• Michael on Instagram: https://www.instagram.com/michaeldbrandt/• Ketone-IQ: https://ketone.com• Ketone-IQ on IG:https://www.instagram.com/ketone/Timestamps:0:00 - Building a New Category From Scratch: Why It's Harder (and Bigger) Than Anything Else1:18 - How Ketone IQ Started: Oxford, the Military, and $30-a-Shot Pro Athletes4:01 - What Ketones Actually Do and Why Michael Got Obsessed7:08 - The DoD Relationship: Research, Procurement, and On-Base Retail8:02 - The Early Positioning Problem: Ketones ≠ the Keto Diet10:22 - Why Sampling Is Everything for a Product You Actually Feel13:36 - Jon Bier's Regret: Why He Didn't Invest (And Why the Odds Were Against It)15:18 - How Marathon Running Gave Michael the Belief to Do the Impossible21:25 - The First Sign of Real Momentum: People Who Tried It Couldn't Stop23:17 - "We're Not Selling Ketones — We're Selling a Feeling"25:03 - Grün, Element, and How to Win Without a Product People Can Feel29:27 - Trend Proof vs. Trend Dependent: Why Ketones Are a Nutritional Primitive32:43 - How Jon Bier Spots Winners (And Why Most Brands Fail Because They're Too Early)35:26 - How to Cannibalize Yourself Before a Competitor Does39:10 - The Jake Paul and Jeff Wu Connection (and the Antifund Story)41:43 - What the Rogan Partnership Actually Means for a Brand45:40 - Why DTC Alone Is Dead and Retail Is the Startup Within the Startup49:08 - Why the Brands That Won DTC Stopped Innovating53:26 - How Celebrity Ambassadors Unlock Retail Doors56:03 - What Retailers Actually Want to Hear (It's Not About the Product)1:00:07 - Why Big Companies Destroy the Brands They Buy1:02:50 - Where Ketone IQ Is Now and What the Exit Math Looks Like1:05:10 - What Michael Would Actually Do With the Money
You're not imagining your fibromyalgia pain or symptoms. Discover common fibromyalgia causes and triggers, and learn how to find fibromyalgia relief by addressing the underlying issue.0:00 Introduction: Fibromyalgia explained 0:42 Fibromyalgia causes and triggers 1:45 Low vitamin D and fibromyalgia3:19 Mitochondrial damage and fibromyalgia symptoms5:00 What to do for fibromyalgia relief5:31 Fibromyalgia research and recovery7:58 Fixing low vitamin D 8:39 Magnesium deficiency and fibromyalgia symptoms 10:34 More fibromyalgia relief tips
Dr Erin Louise Bellamy Dr Erin Louise Bellamy is a Chartered Psychologist, Metabolic Psychiatry Practitioner, and CEO of IKRT (ikrt.org), an international organisation advancing ketogenic metabolic therapy (KMT) for mental health. She holds a PhD in Psychology (ketogenic diets and depression) and a master's degree (MSc) in Psychiatric Research from King's College London and is a Research Fellow at the University of East London. With over a decade of experience researching and implementing KMT, Erin integrates clinical practice, education, and research to improve mental health outcomes. She is an Associate Fellow of the British Psychological Society and a member of the Society of Metabolic Health Practitioners. Link to Show Notes on Website https://fabulouslyketo.com/podcast/262 Dr Erin’s Top Tips If you’re dealing with mental health symptoms, consider ketogenic therapy. Use ketogenic therapy if you are taking any medications to offset the negative side effects Approach ketogenic therapy with the same daily commitment as you would if it was medication Resources Mentioned New Atkins For a New You: The Ultimate Diet for Shedding Weight and Feeling Great – Dr Eric C Westman, Dr Stephen D Phinney and Dr Jeff S Volek Connect with Dr Erin Louise Bellamy on social media Twitter: https://x.com/erinlbellamy and https://x.com/ikrt_org Facebook Page: https://www.facebook.com/profile.php?id=61554863570171 Instagram: https://www.instagram.com/erinlouisebellamy/ and https://www.instagram.com/ikrt_org/ LinkedIn: https://www.linkedin.com/in/erin-louise-bellamy/ and https://www.linkedin.com/company/integrative-ketogenic-research-and-therapies YouTube:https://www.youtube.com/@FabulouslyKeto Website Details: https://www.ikrt.org The Fabulously Keto Diet & Lifestyle Journal: A 12-week journal to support new habits – Jackie Fletcher If you have enjoyed listening to this episode – Leave us a review By leaving us a review on your favourite podcast platform, you help us to be found by others. Support Jackie Help Jackie make more episodes by supporting her. If you wish to support her we have various options from one off donations to becoming a Super Fabulously Keto Podcast Supporter with coaching and support. Check out this page for lots of different ways to support the podcast. https://fabulouslyketo.com/support Or You can find us on Patreon: https://www.patreon. com/FabulouslyKeto Connect with us on social media https://www.facebook.com/FabulouslyKeto https://www.instagram.com/FabulouslyKeto1 https://twitter.com/FabulouslyKeto https://www.youtube.com/@FabulouslyKeto Facebook Group: https://www.facebook.com/groups/FabulouslyKeto Music by Bob Collum Recommend a guest We would love to know if you have a favourite guest you would like us to interview. Let us know who you would like to hear of if you have a particular topic you would like us to cover. https://fabulouslyketo.com/recommend-a-guest We sometimes get a small commission on some of the links, this goes towards the costs of producing the podcast.
Leave an Amazon Rating or Review for my New York Times Bestselling book, Make Money Easy! Check out the full episode: https://greatness.lnk.to/1928DM Most people have spent years obsessing over what to eat. Dr. Mindy Pelz says that's exactly the wrong question. Your body runs two energy systems. One runs on food. The other only kicks in after 8 to 10 hours without eating. That's the fat-burning, brain-sharpening, hunger-suppressing system. Most people never get there. That's why diets keep failing. You're only working with half the machine. Mindy breaks down how to train into fasting gradually. Trying to jump straight to long fasts is like running a marathon with three weeks of 3-mile runs. Lewis learned that the hard way. She also gives one dead-simple rule for timing meals: eat when it's light out. Once darkness hits and melatonin rises, your body stores what you eat as fat. The suffering at hour 12? That's your body repairing itself. That's the point. Sign up for the Greatness newsletter: http://www.greatness.com/newsletter Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
In this episode, coach Daniel Rowland and myself each bring two recent research studies to the table that we have found interesting and potentially useful for athletes and coaches. We discuss the implications and practical takeaways of the findings, how athletes can implement the findings in practice, and the strengths and weaknesses of the different studies. Whether you listen for the love of endurance sports science, or because you want to keep up to date with the cutting edge in triathlon training, this one is for you. HIGHLIGHTS AND KEY TOPICS: A study looking into two types of torque training: very short maximal effort low-cadence sprints, and classic four-minute torque intervals just below Critical Power. Does ketone ester supplementation have direct performance-enhancing benefits? How age-group triathletes actually carb-loaded before the Ironman World Championships - did they hit the optimal amounts of carbohydrates or not? A review on the science of pacing, and practical takeaways including specific sessions to improve pacing. DETAILED EPISODE SHOWNOTES: We have detailed shownotes for all of our episodes. The shownotes are basically the podcast episode in written form, that you can read in 5-10 minutes. They are not transcriptions, but they are also not just surface-level overviews. They provide detailed insights and timestamps for each episode, and are great especially for later review, after you've already listened to an episode. The shownotes for today's episode can be found at https://scientifictriathlon.com/tts698/ LINKS AND RESOURCES: Daniel's Substack (Endurance: Ideas + Implementation) and website The Role of Pedaling Intensity During Torque Training in Cyclists: A Three‐Arm Randomized Controlled Trial - de Pablos et al. 2026 Post‐exercise ketone supplementation improves endurance performance and mitochondrial adaptations during an 8‐week endurance training intervention - Robberechts et al. 2026 From Intention to Execution: Pre-Race Nutrition Behaviours, Influences, and Performance Outcomes in Female Endurance Athletes at the IRONMAN® World Championships - Fortis et al. 2026 Developing negative split pacing in endurance athletes: practical guidelines and training models - Grivas et al. 2026 WHAT SHOULD I LISTEN TO NEXT? If you enjoyed this episode, I think you'll love the following related episodes: John Wakefield of Red Bull BORA hansgrohe – cycling coach and bike fitter | EP#465 - for more on torque training Carbohydrates – science and practice with Tim Podlogar, PhD | EP#354 - for more on carb loading Glycogen metabolism and optimising glycogen resynthesis with Bob Murray, PhD | EP#252 - for even more on carb loading Brendan Egan, PhD | EP#407 - for more on ketones Pacing science and training talk with Andy Renfree, PhD | EP#349 - for more on pacing You can find our full episode archives here, where you can filter for categories such as Training, Racing, Science & Physiology, Swimming, Cycling, Running etc. You can also find separate archives for specific series of episodes I've done, specifically Q&A episodes, TTS Thursday episodes, and Beginner Tips episodes. LEARN MORE ABOUT SCIENTIFIC TRIATHLON: The Scientific Triathlon website is the home of That Triathlon Show and everything else that we do Contact us through our contact form or email me directly (note - email/contact form messages get responded to much more quickly than Instagram DMs) Subscribe to our Newsletter Follow us on Instagram Learn more about our coaching, training plans, and training camps. We have something to offer for everybody from beginners to professionals. HOW CAN I SUPPORT THAT TRIATHLON SHOW (FOR FREE)? I really appreciate you reading this and considering helping the show! If you love the show and want to support it to help ensure it sticks around, there are a few very simple things you can do, at no cost other than a minute of your time. Subscribe to the podcast in your podcast app to automatically get all new episodes as they are released. Tell your friends, internet and social media friends, acquaintances and triathlon frenemies about the podcast. 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A screencast from Chapter 21 in CH 223 entitled “Ketones, Aldehydes and Carboxylic Acids”
It's In The News, where we bring you the top diabetes stories and headlines happening now. Top stories this week: Dexcom shares details of its next generation CGM, T1D and GLP-1 studies, weight loss management on GLP-1 medications updates, all-in-one CGM and pump, and more! Announcing Community Commericals! Learn how to get your message on the show here. Learn more about studies and research at Thrivable here Please visit our Sponsors & Partners - they help make the show possible! Omnipod - Simplify Life All about Dexcom All about VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com Episode transcript: XX Dexcom announces some features of it's next generation CGM – the G8. We've been talking about this with CEO Jake Leach for a while now – it will be a 50% smaller with what they're calling advanced sensing capabilities. According to Leach, G8 will adapt to the physiologic variability of each user. It has additional technology built in, based on a new silicon chip design and algorithm. 15 day wear is now the baseline for all Dexcom sensors moving forward. At launch the G8 will only measure glucose but the plan is for a multi-analyte version to follow. That would measure ketones and potassium. Ketones we know – but potassium is very important for people with kidney and possible for people taking some diabetes meds. It's an interesting space to watch.. btw, analyte is just a medical word for the specific thing you're measuring – the target of the test you're running. we're going to hear that word a lot I think.. Looks like an FDA submission for the G8 next year.. with an outside the US launch the following year. https://www.drugdeliverybusiness.com/dexcom-unveils-next-gen-g8-cgm/ XX Glucotrack has submitted its implantable continuous blood glucose monitor (CBGM) for FDA IDE, that's investigational device exemption and would enable the company to initiate a U.S. clinical study for the fully implantable technology. Rutherford, New Jersey-based Glucotrack's device features no on-body external component. The company aims to offer it for three years of continuous, accurate blood glucose monitoring for a more convenient, less intrusive solution. Unlike traditional CGMs that measure glucose in interstitial fluid, the CBGM measures glucose levels directly from the blood. The implant goes five centimeters within the subclavian vein. Glucotrack's active implantable device has a small battery and some electronics that go just under the skin in the pectoral region. The location of the implant is not in a major vessel, but the implant can measure real-time glucose levels as pulsatile blood flows over the tip of the sensor. https://www.drugdeliverybusiness.com/glucotrack-submits-long-term-implantable-cbgm-fda-ide/ XX PharmaSens today announced the publication of data from the first clinical study evaluating its all-in-one insulin patch pump offering. The all-in-one pump pairs the Niaa Essential insulin patch pump with the SynerG continuous glucose monitor (CGM) sensor developed by Pacific Diabetes Technologies. However, this system would be one device that features both the pump and CGM technology. PharmaSens and SiBionics also have a collaboration aimed at developing the all-in-one solution. They are jointly developing the next-generation Niia insulin patch pump with a SiBionics CGM. PharmaSens expects a second feasibility study in the second quarter to evaluate the next-generation pump with SiBionics' CGM. PharmaSens says the clinical feasibility study of Niia demonstrated for the first time ever that the combined offering is, in fact, feasible. It believes its device addresses the need for alternatives to multi-device diabetes management. systems. Aggregated MARD for the investigational device came in at 11.6%. A MARD target of less than 10% is considered ideal for CGM devices, but PharmaSens said that, in the context of the early feasibility study, the results were encouraging and provide evidence supporting the development of an all-in-one system. https://www.drugdeliverybusiness.com/pharmasens-efs-insulin-patch-pump-cgm/ XX XX ViCentra launches the newest version of the Kaleido pump system in Europe. This is that small colorful pump, with Diabeloops algorithm and the Dexcom G7. It'll be in Germany and the Netherlands later this summer. https://hellokaleido.com/vicentra-announces-commercial-launch-of-new-smartphone-controlled-kaleido-automated-insulin-delivery-patch-pump-system/-- XX Diabeloop just got CE Mark approval for DBLG2 integrations – it's latest AID platform the company has kicked off the gradual European launch of the technology. It currently offers DBLG2 as a smartphone application on Android, with iOS integration coming soon. As you just heard, it's integrated with kaleido and the company says it plans to make additional configuration for DBLG2 with alternative pumps "available soon." Running on a user's smartphone, DBLG2 works as a self-learning algorithm. It continuously analyzes glucose data, calculates insulin needs in real time and automatically adjusts delivery. https://www.drugdeliverybusiness.com/diabeloop-fda-next-gen-algorithm-g7/ XX Among adults with type 1 diabetes (T1D), the initiation of GLP-1-based therapy was associated with a lower risk for all-cause death, several cardiovascular outcomes, all-cause hospitalisations, and hypoglycaemia, without a higher risk for diabetic ketoacidosis. METHODOLOGY: Researchers in Greece conducted a retrospective cohort study utilising real-world data from a global health research network to evaluate the association between GLP-1-based therapy and cardiovascular and renal outcomes in adults with T1D. A total of 4088 patients receiving GLP-1-based therapies (median age, 43 years; 34.3% men) were propensity score matched with an equal number of patients not receiving the treatment. The risk for hypoglycaemia was lower with GLP-1-based therapy (hazard ratio, 0.72; P = .021); however, the risk for diabetic ketoacidosis did not differ significantly between the two groups. https://www.medscape.com/viewarticle/glp-1-drugs-tied-cardiovascular-benefits-t1d-2026a1000fbx XX Eli Lilly and Company (NYSE: LLY) today announced detailed results from two late-phase trials showing that people with obesity maintained their weight loss long term with either Foundayo or lower-dose Zepbound after switching from higher doses of injectable incretin therapy. The findings from SURMOUNT-MAINTAIN and ATTAIN-MAINTAIN, were presented at the 33rd European Congress on Obesity (ECO) and published in The Lancet and Nature Medicine, respectively. "Weight regain remains one of the biggest challenges in obesity care, and is often the result of treatment interruptions that cause biology to work against patients, undoing the progress they've made," said Louis J. Aronne, M.D., FACP, DABOM, founder and Chair Emeritus of the American Board of Obesity Medicine, former president of The Obesity Society, Fellow of the American College of Physicians, world-renowned obesity specialist and Lilly consultant. "These medicines can be used for long-term maintenance today, and results from SURMOUNT-MAINTAIN and ATTAIN-MAINTAIN provide additional evidence of their potential when switching from higher doses of injectable incretin therapy." https://investor.lilly.com/news-releases/news-release-details/lillys-foundayo-and-lower-dose-zepbound-helped-people-maintain XX Scientists in Sweden have developed a more reliable way to create insulin-producing cells from human stem cells. These lab-grown cells not only respond strongly to glucose but were also able to restore blood sugar control when transplanted into diabetic mice. When transplanted into diabetic mice, the cells gradually restored the animals' ability to regulate blood sugar. Long way to go, as we say with most of these mice studies. https://www.sciencedaily.com/releases/2026/05/260505234620.htm XX Interesting look at how the body controls sugar storage – apparently this finding challenges long-standing biology concepts and could open new directions for disease treatment. Published in Nature, the study describes a potential method for directly reducing glycogen, the stored form of sugar in the body. These scientists discovered that glycogen can be directly regulated by ubiquitin, a protein best known for marking damaged proteins for recycling or removal. The study is the first to show that ubiquitin can regulate glycogen in humans, overturning more than 50 years of scientific understanding. Excess glycogen is also associated with more common health problems, including diabetes, obesity, liver disease, and heart disease. https://scitechdaily.com/scientists-just-rewrote-biology-hidden-mechanism-could-transform-diabetes-treatment/ XX A new Oklahoma law will give parents the option to have their children screened for Type 1 Diabetes. The measure passed with overwhelming bipartisan support in the Legislature and takes effect Nov 1. Oklahoma consistently ranks among the states with the highest rates of diabetes and diabetes-related deaths. The law gives parents access to antibody testing that can detect risk years before symptoms develop, helping families take preventive action and avoid emergency room visits. https://journalrecord.com/2026/05/11/oklahoma-law-expands-access-type-1-diabetes-screening/ XX More to come including a new study trying to figure out why some people are more likely to develop diabetes, a look at cannabis and preventing metabolic disorders, and XX A National Institutes of Health (NIH)-funded study has identified key differences in human pancreatic islet cells that may help explain why some people are more likely to develop diabetes. Researchers found that the mix of hormone-producing cells in the pancreas varies widely from person to person, and that variation plays a central role in how the body regulates blood sugar. The study involved a deep dive into islet cell function that is linked to donor traits associated with observable characteristics, or phenotype, such as sex, race and ethnicity, as well as genetic information, or genotype, including predicted ancestry and genetic risk for both type 1 and type 2 diabetes. The findings highlight that islet cell composition, rather than the physical size and shape of islets, is a key factor in regulating hormone release. The team found that the makeup of pancreatic islets plays a major role in how effectively they release insulin and glucagon — key hormones that regulate blood glucose. Islets with a higher proportion of insulin-producing beta cells showed stronger insulin secretion in response to various stimuli, while higher levels of alpha and delta cells were generally linked to reduced insulin output. In addition, the researchers found that islet hormone secretion is affected by donor traits, such as sex, race and ethnicity and their genetic makeup, including ancestry predicted from genetic testing and genetic risk for type 2 diabetes. Combined, the findings of the study have significant implications for understanding the factors that may predispose people to diabetes. "This study is the tip of the iceberg," said Dr. Evans-Molina. "We hope this dataset becomes useful to the entire diabetes research community and that researchers use it to answer questions about the genotype-phenotype correlation within these data." https://www.nih.gov/news-events/news-releases/nih-funded-study-maps-human-pancreatic-islet-cells-offering-new-clues-diabetes-risk XX XX XX Research published recently in JAMA Network Open offers illuminating evidence suggesting there is a positive association between GLP-1 agonists—drugs commonly used to treat obesity and diabetes—and better outcomes among breast cancer patients. "This study suggests that GLP-1 drugs may offer protective benefits potentially improving survival and recurrence risk in some female patients with breast cancer – whether this is related to weight control, improve cardiovascular health or other mechanisms remains to be studied," said study senior author Bernard F. Fuemmeler, Ph.D., MPH, associate director for population sciences and the Gordon D. Ginder, M.D., Chair in Cancer Research at VCU Massey Comprehensive Cancer Center. Breast cancer patients who are also obese or have type 2 diabetes experience more aggressive cancer growth and worse outcomes. Prior studies have shown that weight loss treatment and surgery following a breast cancer diagnosis are associated with improved heart health and increased survival. What are GLP-1 drugs? Glucagon-like peptide-1 receptor agonists (GLP-1 RAs). Approved to treat type 2 diabetes in 2005 and weight management in 2021. Impacts on breast cancer survival and recurrence are still unclear. Since 2020, the use of these drugs has increased dramatically, where approximately 12% of Americans have used GLP-1s for weight loss, according to a RAND report. The research findings Through a retrospective cohort study examining the electronic health records of more than 840,000 breast cancer patients who were diagnosed between 2006 and 2023, the results suggest there is a potential link between GLP-1 RAs and improved outcomes among breast cancer patients who are also obese or have type 2 diabetes. GLP-1 RA use was associated with an overall lower risk of death from any cause over a 10-year follow-up period among breast cancer patients. Additionally, breast cancer survivors who used GLP1-RAs for diabetes or obesity had a significantly lower risk of their cancer returning over 10 years following their initial treatment. "Our findings align with emerging preclinical research and contribute to a growing body of literature related to GLP-1 RA use in oncology settings," said study lead author Kristina L. Tatum, PsyD, MS, of the VCU School of Public Health. What's next? Further studies are needed to understand the biological mechanisms, if any, between GLP-1 RAs and breast cancer outcomes. The research team intends to further evaluate these correlations through randomized clinical trials. "Our study underscores the potential of GLP-1 RAs as an adjunct strategy for improving cancer-related outcomes among patients with breast cancer, although clinical trials are needed to inform effective therapeutic approaches and clinical decision making," Fuemmeler said. https://www.oncology-central.com/could-glp-1-receptor-agonists-improve-outcomes-for-breast-cancer-patients-with-obesity-or-with-type-2-diabetes/ XX Researchers at UC Riverside gave cannabis to obese mice and found that not only did the rodents lose weight, but when given a concentrated cannabis oil, the mice also saw striking benefits in their metabolic function. DiPatrizio said his team studied the issue to better understand why cannabis users show significant reductions in weight and risk for diabetes compared with nonusers. "We would think that chronic cannabis users would be eating more and weigh more, but it's just the opposite," DiPatrizio said. Scientists are increasingly examining the possibility that cannabis compounds could fight obesity or metabolic disorders like diabetes. Cannabinoids interact with the body's endocannabinoid system, which partially controls nearly every aspect of our physiology, including metabolism and appetite. That creates the possibility that targeting this widespread system could unlock new therapies for these conditions. https://www.sfgate.com/cannabis/article/cannabis-weight-loss-california-study-22255328.php XX A new campaign launched by diaTribe and Genentech aims to empower and educate people about diabetes-related eye disease. Here's what you can do today to protect your eye health. To help address these barriers, diaTribe and Genentech partnered to launch All Eyes on DME, a new campaign that aims to spread awareness and educate people at-risk for or living with diabetes-related eye conditions like DME. Also partnering in the campaign is actor and comedian Damon Wayans, who wanted to share his journey (and, of course, a joke or two) with type 2 diabetes to open up the conversation about what is often a stigmatized or less talked about topic: eye health and diabetes. One of these important conversations happened recently at the All Eyes on DME launch in New York City, where Wayans joined a panel of experts, advocates, and people living with DME to talk about diabetes-related eye disease and how to help prevent it. https://www.alleyesondme.com/dme-in-the-spotlight.html https://diatribe.org/diabetes-complications/all-eyes-dme-new-campaign-spotlights-eye-health-and-diabetes
Every diet you've ever tried has failed you for one reason: it never told you when to eat. Your body runs on two energy systems. One burns sugar. The other burns fat. Most people never spend a single day in the second one. Around eight to ten hours without food, the switch flips. Ketones flood your brain. Hunger quiets. Mental clarity hits. Healing turns on. This is what fasting expert Dr. Mindy Pelz has been teaching for over 25 years, and what her book Fast Like a Girl made impossible to ignore. For women, timing is everything. Day 1 to 10, fast longer and lift heavier. Day 11 to 15, testosterone surges and libido climbs. Day 16 to 19 is for deeper fasts. After day 20, progesterone needs you to back off and rest. Fast like a man during the back half of your cycle and you'll tank the very hormones keeping you calm and regular. Underneath all of it sits the hormonal hierarchy. Oxytocin at the top. Cortisol below it. Then insulin. Then sex hormones. When you feel safe and connected, the whole stack works. When you don't, nothing else matters. Connection isn't optional for women. It's biology. Dr. Mindy's books: Age Like a Girl How Menopause Rewires Your Brain for Mental Clarity, Increased Confidence, and Renewed Energy Eat Like a Girl: 100+ Delicious Recipes to Balance Hormones, Boost Energy, and Burn Fat Fast Like a Girl: A Woman's Guide to Using the Healing Power of Fasting to Burn Fat, Boost Energy, and Balance Hormones The Menopause Reset: Get Rid of Your Symptoms and Feel Like Your Younger Self Again The Reset Factor Kitchen: 101 Tasty Recipes to Eat Your Way to Wellness,Burn Belly Fat, and Maximize Your Energy The Reset Factor: 45 Days to TransformingYour Health by Repairing Your Gut In this episode you will: Learn the fasting cycle for women, Dr. Mindy's day-by-day framework that syncs your fasting window, workout intensity, and food choices to your menstrual cycle Uncover why your menstrual cycle is a monthly detox rather than a burden, and what an irregular or absent cycle is actually telling you about your body Discover why timing your eating matters more than what you eat, and how the ketogenic energy system unlocks fat burning, mental clarity, and steady energy Understand the hormonal hierarchy, how oxytocin, cortisol, insulin, and sex hormones stack on each other, and why female community and connection function as biological medicine Find out what long-term birth control does to the gut microbiome and the brain-ovary connection, and why so many women struggle with hormonal imbalances after coming off the pill For more information go to https://lewishowes.com/1928 For more Greatness text PODCAST to +1 (614) 350-3960 Follow The Daily Motivation for essential highlights from The School of Greatness More SOG episodes we think you'll love: Glucose Goddess Dr. Mary Claire Haver Dr. Mark Hyman TOPICS Dr. Mindy Pelz, intermittent fasting, ketogenic energy system, fasting cycle for women, hormonal hierarchy, menstrual cycle nutrition, cortisol and stress, birth control and microbiome, oxytocin and women's health, Fast Like a Girl Get more from Lewis! Get my New York Times Bestselling book, Make Money Easy!Get The Greatness Mindset audiobook on SpotifyText Lewis AIYouTubeInstagramWebsiteTiktokFacebookX Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Ketones may be the most underrated fuel source in human metabolism, and most people only hear about them in the context of intermittent fasting or the ketogenic diet. When your body burns fat, it produces ketones- molecules that have been shown to support brain health, heart health, cognitive function, and longevity. The problem is that fasting and strict keto aren't realistic for most people, so the question is: Is there actually a way to get the benefits of ketones without giving up food? That's exactly what my guest this week on the Medical Disruptor set out to answer. Dr. Latt Mansor earned his PhD in metabolism from Oxford and is the lead scientist behind Ketone-IQ, a ketone-based drink that gives the body the same fuel source you'd typically only access through fasting. In this episode of The Medical Disruptor, we're going deep on how ketones work, why your metabolism may be the missing piece in your health story, and how to use ketosis to take your energy, focus, and longevity to the next level. I cover what ketones really are and why your brain and heart love them, the science behind intermittent fasting, paleo, and ketogenic diets, and why so many women are told their fatigue and brain fog are "normal" when their metabolism is actually the root cause. We get into how exogenous ketones work, who they're for, and practical ways to use them without overhauling your entire life. If you've been medically gaslit about your energy, your weight, or your metabolic health and told everything looks "fine," this conversation is going to give you a completely different lens. You don't have to fast to feel better. You just need the right information, and that's what we're here for. Get your ketones here → https://ketone.com/disruptor Want more practical health tips? Join my newsletter! https://freechapter.lpages.co/newsletter-opt-in/ Check us out on social media: https://www.instagram.com/drefratlamandre https://www.facebook.com/drefratlamandre https://www.tiktok.com/@drefratlamandre #functionalmedicine #drefratlamandre #medicaldisruptor #NPwithaPHD #nursepractitioner #medicalgaslighting Chapters 00:00 - Introduction 03:49 - The $6M Military Study 05:23 - Latt's Personal Transformation 13:30 - What Is Ketosis 15:13 - Why the Brain Loves Ketones 20:47 - What Are Exogenous Ketones 25:17 - Ketones & Heart Failure 29:13 - Ketones & Alzheimer's 33:46 - Exogenous Ketones vs Keto Diet 36:17 - Ketones & Insulin Resistance 39:33 - What Medicine Needs to Change Guest Links: FB: https://www.facebook.com/latt.shahril.mansor IG: https://www.instagram.com/lattmansor/ Website:www.ketone.com Learn more about your ad choices. Visit megaphone.fm/adchoices
The belief that IV dextrose is necessary to clear ketones in hyperemesis gravidarum originated from a logical, and now known to be outdated, extrapolation of basic starvation ketosis physiology and the treatment paradigm for diabetic ketoacidosis (DKA). The original experiments that led to this conclusion go back to the 1960s (Foster data). Not only is this outdated, but it is also physiologically incorrect. We've learned a lot about IV fluid replacement about hyperemesis gravidarum in the last several years- in the last data review was in January 2026 in Lancet. Even the correction of hyponatremia has evolved. Should we be following urine ketones for patients being treated for HG? Is Dextrose needed? Listen in for details.1. Nana M, Painter R, Williamson C et al. Hyperemesis gravidarum. The Lancet, Jan 2026; 407, 78-892. Clark SM, Zhang X, Goncharov DA. Inpatient Management of Hyperemesis Gravidarum. Obstet Gynecol. 2024 Jun 1;143(6):745-758. doi: 10.1097/AOG.0000000000005518. Epub 2024 Feb 1. PMID: 38301258.3. Ayus JC, et al.Correction rates and clinical outcomes in hospitalized adults with severe hyponatremia: a systematic review and meta-analysis. JAMA Intern Med. 2025;185(1):38-51. 4. ACOG Clinical Epert Series: Inpatient Management of Hyperemesis Gravidarium. Obstet Gynecol; 2024
Can a ketogenic diet affect your thyroid? What about bone health, uric acid, cannabis use, or ketone supplements?In this Metabolic Mailbag episode, Dr. Bret Scher and Dr. Georgia Ede answer your most pressing questions about ketogenic therapy and how it interacts with real-world health concerns.From thyroid function to mental health, this conversation highlights how nuanced and individualized metabolic therapies can be.You'll learn:How ketogenic diets influence thyroid hormones, and why lower T3 doesn't necessarily mean hypothyroidismWhen to monitor thyroid function more closely, especially with pre-existing conditions or medications like lithiumWhat the evidence says about protein intake, uric acid, and bone healthWhy temporary changes during the adaptation phase (like uric acid fluctuations) may not reflect long-term outcomesHow cannabis use may affect appetite, cravings, and adherence to a ketogenic dietWhether exogenous ketones and MCT oil provide the same benefits as nutritional ketosisDr. Ede also shares a key principle: context matters. Lab values, symptoms, and individual biology all need to be considered together, especially when using ketogenic therapy for mental health or metabolic conditions.The key takeaway: ketogenic therapy is not one-size-fits-all. It's a dynamic, personalized approach that often requires thoughtful monitoring, adjustments, and collaboration with a knowledgeable clinician.
In this episode, Dr. David Jockers dives into the transformative benefits of a seven-day water fast. He explores how fasting balances blood sugar, improves insulin sensitivity, and triggers deep cellular healing, making it a powerful tool for weight loss and overall health. You'll learn how fasting helps the body burn fat, repair mitochondria, and reset the immune system. Dr. Jockers breaks down the science behind autophagy and mitophagy, showing how your body eliminates damaged cells to replace them with healthier, stress-resistant ones. Plus, discover the critical role ketones play in brain health and how fasting elevates stem cell production. With insights on how to prepare for and break a fast, you'll get practical tips for maximizing the benefits of extended fasting. In This Episode: 00:00 Key Fasting Milestones 04:17 Why Fast Seven Days 04:53 Blood Sugar and Fat Burn 06:23 Ketones and Brain Benefits 07:40 Autophagy and Mitochondria 08:37 Gut Microbiome Reset 10:20 Hormones Longevity Stem Cells 16:06 Research and Immune Tregs 18:08 Hour by Hour Breakdown 20:07 Five vs Seven Days 21:03 What to Drink While Fasting 22:54 Prep Meals Before Fasting 24:19 How Often and Exercise 25:29 Breaking the Fast Safely 26:50 Wrap Up and Final Thanks Hair loss isn't just about age—it's about hair follicles getting stuck. AnaGain Nu by Purality Health uses a pea sprout extract clinically shown to reactivate follicles and boost regrowth. With their micelle liposomal delivery, your body absorbs it fast and effectively. Try it risk-free with a 180-day money-back guarantee and get a buy-one-get-one-free deal at RenewYourHair.com - https://renewyourhair.com/drj. Looking to boost your hair growth and enhance your skin health? Now's the perfect time to try iRestore's Elite Laser Hair Growth System and the Illumina Face Mask, both designed to give you thicker hair and smoother, more radiant skin. Take advantage of the Memorial Day savings event and grab this powerful bundle at an exclusive discount. Visit iRestore.com and use code DRJOCKERS to claim your offer today. "Fasting for 36–48 hours can reset your brain and dopamine, giving you a clearer mind and better mental health." ~ Dr. Jockers Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio Resources: Reignite hair growth with AnaGain Nu, risk-free with a 180-day guarantee and a buy-one-get-one-free deal! https://renewyourhair.com/drj Visit iRestore.com and use code DRJOCKERS to claim your offer today Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/
You broke a 5-day dry fast. Two days later, you've got a cold sore, a shingles patch, or that crushing post-mono fatigue is back. Almost everyone blames the fast. They're looking at the wrong window.The dry fast is the safest period your immune system experiences all year. Autophagy is destroying virus-occupied cells. Ketones starve viruses of the glucose metabolism they need. mTOR (the growth signal viruses hijack to replicate) is shut down. And NK cell activity is climbing. Inside that fasted state, viral replication is mechanically and metabolically near-impossible. That's why most people don't flare during the fast itself.The danger is the refeed. The moment food comes back, mTOR turns back on, autophagy shuts off, your T-cells are still parked in bone marrow, cortisol is still peaking, and T3 is still crashed. For 24 to 72 hours your antiviral defences are at zero — and any virus that survived the fast now has an open road to refill the reservoirs the fast just cleared. Worse, it can spread to nerve cells it never previously occupied.In this video I break down:— Why the dry fast creates a near-impenetrable antiviral state (4 mechanisms)— Why the refeed is the highest-risk window in the entire protocol (5 mechanisms)— Why a botched refeed leaves chronically ill patients MORE infected than they started— The bridge strategy: dry fast → water fast → controlled refeed with antivirals already on board— The full pharmacological stack: T3, L-lysine, monolaurin, acyclovir, ivermectin— Early warning signs of reactivation in the refeed window (and what to do)— Why this gets dramatically easier from cycle 3 onward— The T3 off-ramp as the second high-risk window most people missThis isn't a reason to fear fasting. It's the map of when the danger window opens and how to close it before food can.
The 14-Day Metabolic Reset
A ketogenic diet put his ulcerative colitis into complete remission — off all medications, confirmed on colonoscopy. Dr. Nick Norwitz (PhD Oxford, MD Harvard) explains why evidence-based care isn't always optimal care, how keto rewires the gut and brain, and why GLP-1 drugs should catalyze lifestyle change, not replace it.CHAPTERS:0:00 - The most remarkable thing about my story is it's not unique1:14 - Welcome Nick Norwitz — Oxford PhD, Harvard MD2:02 - Ulcerative colitis, desperation, and keto remission5:34 - What medical school doesn't teach8:05 - Why evidence-based care ≠ optimal care15:53 - The carnivore-ketogenic IBD case series (10 patients)18:50 - Fiber elimination in pediatric Crohn's — 60–85% remission20:00 - Keto for depression: Ohio State trial — 69–71% reduction23:49 - Seed oils: the nuanced truth29:32 - Ketones and neurodegenerative disease32:52 - Autophagy, lateral habenula, and depression36:16 - Sonnenburg 2021: fermented foods beat fiber for inflammation37:20 - GLP-1 agonists: good tool, poor deployment43:29 - Statins slash GLP-1 by ~50% (Cell Metabolism, 2024)48:57 - ClosingREFERENCES:Carnivore-Keto for IBD (Norwitz et al., Frontiers, 2024): PMC11409203Keto for Depression (Ohio State, 2025): PMC12420795Fermented Foods vs Fiber (Sonnenburg, Cell, 2021): Stanford NewsStatins Slash GLP-1 (Cell Metabolism, 2024): pubmed/38325336Autophagy + Depression (Nature, 2025): NatureGUEST: Nick Norwitz, PhD MDHOST: Dr. Robert Lufkin MD | robertlufkinmd.com⭐ Enjoying the show? Please leave a 5-star review on Apple Podcasts — it takes 30 seconds and helps more people discover the science of health and longevity. Thank you!New episodes every Tuesday & Thursday. Subscribe so you don't miss one.Continue this conversation on Substack: https://robertlufkinmd.substack.comLies I Taught In Medical School — Free sample chapter: https://www.robertlufkinmd.com/lies/Web: https://www.robertlufkinmd.comYouTube: https://www.youtube.com/robertlufkinmdX: https://x.com/robertlufkinmdInstagram: https://www.instagram.com/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinLinkedIn: https://www.linkedin.com/in/robertlufkinmd/
Stephen explores the fascinating biological processes behind eye health, ketone production, and the impact of insulin resistance. Discover how your diet influences retinal health through local ketone synthesis and the implications for preventing eye diseases.Chapters00:00 The Hidden Power of the Retinal Pigment Epithelium05:13 The Role of Ketones in Eye Health10:27 Insulin's Impact on Retinal Health
Rubicon - Janelle King discusses pertinent topics in healthcare
People with pre-diabetes are 2.7 times more likely to develop major depression. People with new bipolar disorder are 3.5 times more likely to have metabolic syndrome. If that stopped you in your tracks, good – it stopped me too. I brought Dr. Georgia Ede back to The Resetter Podcast to dig into her new expert consensus on ketogenic diets and mental health, and this conversation is one every woman needs to hear. Dr. Ede is a Harvard-trained psychiatrist and one of the world's leading experts in nutritional and metabolic psychiatry. What she laid out in this episode completely reframed how I think about brain health, brain energy, and what it actually means to feed your mind. We get into why the brain is a hybrid engine that runs best on a mixture of glucose and ketones and what happens when it runs on glucose alone. If you've ever wondered whether what you eat is affecting how you think, feel, and function – this one will give you the science and tools to find out. For more resources related to today's episode, visit the podcast episode page: https://www.drmindypelz.com/ep334 CONNECT WITH DR. GEORGIA EDE: Change Your Diet, Change Your Mind Instagram: @GeorgiaEdeMD Facebook: @GeorgiaEdeMD LinkedIn: @GeorgiaEdeMD X: @GeorgiaEdeMD CONNECT WITH DR. MINDY: Join Reset Academy Watch the episodes on YouTube Follow Dr. Mindy on Instagram Subscribe to Dr. Mindy's newsletter for tools and research on fasting, hormones, and metabolic health Disclaimer: This podcast is intended for educational and informational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making changes to your diet, fasting routine, or lifestyle.
We imagined doing PG-13 things to a very tasty gel before this great episode! The main training topic was a discussion of steady running. Lots of theory talks about “hard days hard and easy days easy.” But we think there's a place for an addition: “medium days medium.” We discuss the rationale and timing of how to work steady running into a typical week.We also had a big discussion of pregnancy and sponsorships, after Emma Bates announced that she was no longer running for UCAN. We had a few days to calm down, so the angry rants are strong but less intense than they would have been last week. And this one was full of fun topics! Other topics: ankle yeeting, colon health in runners (and David's screening experience), our favorite gels, a data snack connecting sauna use to lower resting heart rate, a study on sodium bicarbonate's effect on 5k performance, a big study on post-exercise ketones improving adaptation, a shocking TUE dashboard, hard candy to simulate the mouth rinse studies, depletion runs, hemoglobin levels, and lots more.Come for the science. Stay for David realizing that his takes are aggressively wrong. We love you all! HUZZAH!-David and MeganClick "Get 40% Off" button for 40% off at The Feed here: thefeed.com/swapBuy Janji's amazing gear: https://janji.com (code "SWAP")The Wahoo KICKR Run is the best treadmill on the market: https://www.wahoofitness.com/devices/running/treadmills/kickr-run-buy (code “SWAP”)For training plans, weekly bonus podcasts, heart rate zones, articles, and videos: patreon.com/swap
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Amy Berger, a low-carb and keto nutritionist, shares her expertise on simple approaches to low-carb living, the benefits of ketogenic and carnivore diets, and the latest insights on Alzheimer's and thyroid health. Discover practical tips, misconceptions, and scientific perspectives to optimise your health journey.https://www.instagram.com/tuitnutritionhttps://www.youtube.com/@amyberger-ketowithoutthecrazyChapters00:00 Introduction to Amy Burger and Her Mission01:59 Understanding Low Carb, Keto, and Carnivore Diets04:33 The Differences Between Low Carb and Keto06:48 Personal Journey into Low Carb and Keto09:13 Alzheimer's Disease and the Role of Ketogenic Diet11:28 The Controversy of Alzheimer's Drug Research12:46 Therapeutic Ketosis and Monitoring Levels15:14 Hypothyroidism: Causes and Treatment19:29 Co-authoring 'End Your Carb Confusion'22:38 The Changing Perception of Dietary Fat24:20 Understanding LDL Cholesterol on a Keto Diet27:09 Common Mistakes in Keto and Carnivore Diets30:21 Artificial Sweeteners and Their Role34:39 Advice for Clients and Information Overload38:10 Frustrations with Lab Metrics and Ranges
Up to 70% of dementia may be preventable, so why aren't more people talking about what actually drives cognitive decline? In this episode, I'm with Dr. Tommy Wood, neuroscientist and author of “The Stimulated Mind,” to explore the lifestyle levers that protect your brain across a lifetime. Learn how white matter hyperintensities develop and whether they can reverse, what MCTs and ketones actually do for a glucose-starved brain, and why social connection may be the most underrated variable in cognitive aging. What is the one change you could make today that would most protect your brain tomorrow?Want ad-free episodes? Subscribe to Forever Strong Insider: https://bit.ly/4u5VSReGet Dr. Tommy Wood's book, “The Stimulated Mind”: https://bit.ly/4bYIUxE Listen to "Better Brain Fitness" on all your favorite platforms!YouTube: https://bit.ly/4bGqxMN Spotify: https://bit.ly/4c0OGPj Apple Podcasts: https://bit.ly/3NL7toq
Dr. Rhonda Patrick, PhD, is a biomedical scientist and public science educator. She shares the exercise, nutrition, supplementation and lifestyle practices linked to better health and lower disease risk including specific cardio and resistance training routines, when and why to do intermittent fasting, ways to lower visceral fat, omega-3 sourcing, creatine for brain and muscle and peptides such as BPC-157. It's broad and thorough coverage of how to build a total health program tailored to your goals and individual biology. Read the show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Our Place: https://fromourplace.com/huberman Lingo: https://hellolingo.com/huberman LMNT: https://drinklmnt.com/huberman Function: https://functionhealth.com/huberman Mateina: https://drinkmateina.com/huberman Timestamps 00:00:00 Rhonda Patrick (00:02:40) Competition, Jumping Rope, Rope Flow (00:06:49) Rhonda's Exercise Routine, Cardiovascular & Resistance Training (00:12:30) Cognitive & Physical Benefits of Exercise, Serotonin & Impulse Control (00:14:40) Sponsors: Our Place & Lingo (00:17:03) Phones While Training? (00:18:45) Rhonda's Strength Training, Low-Reps, Modifications, Mental Resilience (00:27:00) Daily Protein Intake, Intermittent Fasting, Processed Carbohydrates (00:33:32) Lipopolysaccharide (LPS); Gut Permeability, Gluten; Cardiovascular Health (00:42:58) Sponsor: AG1 (00:44:21) Tight Junctions, Gut, Neuroinflammation (00:47:26) L-glutamine, Immune System, Cancer Risk (00:54:55) N-acetylcysteine (NAC), Vitamin E; Antioxidant Balance, Reductive Stress (01:00:08) Starch, Tool: Bedtime Fast & Cardiovascular Health (01:03:36) Cortisol, Intermittent Fasting Benefits (01:08:09) Cortisol, Train Fasted?; Hormones, Visceral Fat (01:13:35) Visceral Fat, Perimenopause/Menopause, Insulin Resistance in Brain & Body (01:21:13) Sponsor: LMNT (01:22:33) Cortisol & Sleep (01:25:42) Intermittent Fasting, Metabolic Switch, Ketones, Muscle Loss? (01:36:47) Tools: Logic-Based Habits; Daily Metabolic Switch; Exercise, Autophagy (01:45:06) Exercise After Poor Sleep?; Training Breaks (01:52:47) Tool: "Exercise Snacks"; Sedentary Lifestyle & Cardiorespiratory Fitness (02:03:31) Sponsor: Function (02:05:16) Creatine, Dose, Resistance Training, Cognitive Function (02:17:43) Biology; Creatine; Supplement Safety (02:25:18) Omega-3s, Inflammation, Cancer Risk, Vitamin D; Trans Fat (02:36:52) Magnesium Threonate vs Bisglycinate, Sleep, Cognitive Benefit; Vitamin D (02:45:46) Supplement Types, Multivitamin, Coenzyme Q10, Urolithin A, Sulforaphane (02:55:10) Microplastics (02:57:26) Sponsor: Mateina (02:58:28) BPC-157, NMN, NR, Tool: Evaluating Supplements, Safety, Sources (03:06:28) L-Carnitine, Alpha-GPC, Nicotine, GABA & Ketogenic Diet (03:15:20) Nattokinase; Microplastics, Water Bottles; Seed Oils (03:22:21) Sauna, Creatine for Kids?, Bananas, Tool: Evaluating Studies (03:28:37) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices
Join us for a new Sh*t Talkers Weekly podcast episode where we discuss comments from YouTube about the podcasts, recent races and Cam's running goals, logic on pushing past excuses, and more! Follow along: Instagram: https://www.instagram.com/cameronrhanes Twitter: https://twitter.com/cameronhanes Facebook: https://www.facebook.com/camhanes/ Website: https://www.cameronhanes.com Timestamps: 00:00:00 – Marty Supreme Movie, Ketones, & Social Media Control 00:04:57 – Comments on Sh*t Talkers Weekly Episodes 00:14:54 – Conspiracies Behind Birth Control 00:20:10 – James Running Logic for Time & Lifting 240lbs 00:23:27 – Cam's Recent Races, Training, & Cam's Running Heart Rate 00:37:10 – Pushing Past the Excuses During Training 00:47:25 – New Merch, Upcoming Guests, James' Training & Triathlons 00:56:21 – Final Thoughts Thank you to our sponsors: Sig Sauer: https://www.sigsauer.com/ use code CAM10 for 10% off optics MTN OPS Supplements: https://mtnops.com/ Use code KEEPHAMMERING for 20% off Good Ranchers: https://www.goodranchers.com/ use code CAMERON for $25 off your first order Hoyt: http://bit.ly/3Zdamyv use code CAM for 10% off Black Rifle Coffee: https://www.blackriflecoffee.com/ Use code KEEPHAMMERING for 10% your orderMontana Knife Company: https://www.montanaknifecompany.com/ Use code CAM for 10% off
Welcome! and Thank you for listening. Don't fall off your exercise ball but we are going to talk low carb and keto! Last week I completed the Long Play 33 with 35 miles- bonus miles as Andy, the race director, would say. Based on a recently published study on nutrition during endurance events, I decided to decrease my glucose intake and add Ketone IQ shots to the mix. I have a history of bonking in the later parts of a race. Sometimes, it is more like the early part. My stomach no longer accepts gels, I feel sluggish, and have assumed it was my mental attitude and the need for more fuel. I figured I was dehydrated leading to a decrease in blood to the gut and inability to digest my intake resulting muscle glycogen depletion. As soon as I started taking gels, I became dependent on them. Once, I could not tolerate them, I was headed for low energy and the need to walk or quit. My new hypothesis is that it is my brain's demand for fuel and my bloodstream dip in glucose that causes the bonk. Wild swings in glucose and insulin followed by a decrease in my ability to burn fat as fuel. So I tried a few new things this race and had a pleasant surprise. I had another pleasant surprise with my follow up lipid and DHA levels. Certainly, a tell all episode. Thanks for listening. Website: doctordulaney.com Email me at Jami@doctordulaney.com Cookbook: amzn.to/4onHVe4 Ebook: doctordulaney.com/.powerful-plates-ebook/?mc_cid-cc24587 Water distillers: https://mypurewater.com/?sld=jdulaney discount code: cleanwaterforsophie https://academic.oup.com/edrv/article/47/2/191/8432248
Kill your vices, sculpt your physique, and become unstoppable with my FREE 6-Step Daily Domination Blueprint. Today I'm joined by metabolic scientist Dr. Latt Mansor to discuss all things ketones. Latt holds a PhD in Physiology, Anatomy, and Genetics from University of Oxford and is the Research Lead at Ketone-IQ; a performance nutrition and metabolic health company. His work has helped shed light on the role ketones play in cognitive function, physical performance, and metabolic health. And he's here to share how ketones impact recovery, mental clarity, and energy production. We also dive into the role ketones play in heart health, metabolic disease, brain function, and more. Find out why ketones are called "nature's superfuel", and how you can use them to supercharge your health, in today's episode... What impact do ketones have on appetite, strength, and recovery? [6:23] Pre or post workout: When is the best time to take ketones? [13:17] Is combining carbs with ketones the optimal performance strategy? [15:07] Ketones vs. stimulants... What's the difference? [20:04] Can ketones treat heart failure and cardiovascular disease? [23:34] Carbs, processed foods, genetics... What really causes insulin resistance? [30:36] What are the physical performance benefits of taking ketones? [39:48] Can ketones reduce the effects of traumatic brain injuries? [45:32] Sponsors AG1: Improve your gut health and immunity, and boost your energy and recovery at drinkag1.com/jay. Marek Health: Take the path to better health, optimized performance, and increased longevity at marekhealth.com - code JAY at checkout for 10% off. Want to work with me to transform your body and mind? Go here now.
Visit lukestorey.com/getqitone and use code LUKE10 to save 10%Longevity isn't about just living longer, but rather living better and longer.Today, I sit down with Dr. Greg Bailey, a former emergency room physician turned biotech investor who now operates at the forefront of longevity science. After a decade in emergency medicine, he transitioned into drug development and cutting-edge research focused on extending healthspan, not just lifespan. We get into the mechanics of ketosis and why metabolic flexibility may matter more than extreme dieting, and the growing role of AI in medicine. Beyond the tech, we address supplement credibility, flawed research, and why connection, purpose, and education remain foundational to real longevity.If you're serious about biohacking, metabolic health, and the future of regenerative medicine, this conversation sets the tone.You'll Learn:[00:00] Introduction[01:29] The creativity and absurdity Greg witnessed in emergency room patients[03:14] Different motivations for pursuing longevity and how desired lifespan changes based on projected health[07:46] Cutting-edge longevity interventions, including epigenetics and cellular reprogramming[12:01] The UCLA study that reversed biological age by two years[15:03] The supplement industry's crisis of trust, why 75% of studies fail replication, and the critical need for credible voices[23:18] Mike Levin's revolutionary bioelectric limb regeneration[33:57] What the ultimate longevity factor is, and today's epidemic of loneliness[39:59] The two pathways to ketosis and why cells prefer ketones over sugar[44:54] Ketones as a potential alcohol replacement for social occasions[49:20] Ketones for brain health across all ages and spermidine's dramatic autophagy effects[01:05:40] Greg's most influential teachers, his mother's profound impact, and my epiphanies I experiencedRelated The Life Stylist Episodes:Surviving the City with Spiritual Science with Dr. Jack Kruse | PodcastThe Toxic Lighting Crisis & How To Fix It with Dr. Jack Kruse, Part 1 | Part 1 and Part 2The 5G EMF Apocalypse & Why Health Food Won't Save You With Dr. Jack Kruse | PodcastThe Ultimate Biohacking Mastermind with Dr. Jack Kruse, Aaron Alexander, & Matt Maruca | PodcastDeuterium Depletion: The Most Powerful Health Hack You've Never Heard Of W/ Dr. Que Collins & Dr. László Boros | PodcastDeuterium Depletion Revisited: The Missing Link With Dr. Anne Cooper | PodcastBadass Biohacks: Deuterium-Depleted Water & Molecular Hydrogen for Extreme Health w/ Robert Slovak | PodcastResources Mentioned:Reversal of epigenetic aging and immunosenescent trends in humans by Fahy, G et al | ArticleA Randomized Open-Label, Observational Study of the Novel Ketone Ester, Bis Octanoyl (R)-1,3-Butanediol, and Its Acute Effect on ß-Hydroxybutyrate and Glucose Concentrations in Healthy Older Adults by Stephens, E et al | ArticleREAD: The Body Electric by Robert O. Becker | BookREAD: A Horse Named Lonesome by Luke Storey | WebsiteA ketogenic diet extends longevity and healthspan in adult mice by Roberts, M et al | ArticleImpact of polyphenol oxidase on the bioavailability of flavan-3-ols in fruit smoothies by Ottaviani, J et al | ArticleSprevive | WebsiteUrolithin A | WikipediaTimeline Mitopure | WebsitePrimeadine Spermidine | WebsiteFull show notes at lukestorey.com/qitoneFind more from Dr. Greg Bailey:Dr. Greg Bailey | WebsiteQitone | Website | Facebook | InstagramFind more from Luke:Luke Storey | Instagram | Facebook | X | YouTube | LinkedInTHE LIFE STYLIST IS BROUGHT TO YOU BY:BIOPTIMIZERS | Visit bioptimizers.com/luke to save 15% off sitewide.QUANTUM UPGRADE | Visit lukestorey.com/quantumupgrade and use code LUKE15 to get your 15-day free trial.BON CHARGE | Use the code LIFESTYLIST for 15% off at boncharge.com/lifestylist.LOTUS WEI | Visit lotuswei.com/luke. Take the Flower Quiz and use code LUKE to save 10%Keywords:longevity science, healthspan, lifespan vs healthspan, aging research, biotech investing, drug development, emergency medicine, ketosis, ketone esters, exogenous ketones, metabolic health, metabolic flexibility, fasting, ketogenic diet, epigenetics, cellular reprogramming, limb regeneration, stem cells, senolytics, NAD pathways, AI in medicine, clinical trials, supplement credibility, regenerative medicine, spermidine, urolithin A, education and longevity, purpose and aging
Tim Tebow is back—and this time he's bringing full-on dad energy. Tim shares the surreal (and hilarious) realities of becoming a father to Daphne Raine, from driving home like a hyper-cautious grandpa to realizing how instantly responsibility rewires your whole brain. Along the way, Levi and Jennie soak up Tim's reflections on what fatherhood has already taught him about God's voice in chaos, and how love turns into action. Then the conversation turns tender and powerful as Tim opens up about his new book If the Tree Could Speak—a poetic, perspective-shifting retelling of the gospel through the life of the tree that became the cross. From Easter tenderness to the brutal honesty of Calvary, this episode is a reminder that the cross changes everything—and that our calling is to live like we actually believe it. Connect with us on social! Tim: @timtebow Levi: @levilusko Jennie: @jennielusko Fresh Life Church: @freshlife [Links] If the Tree Could Speak Book: https://bit.ly/4rqk0fE Look Again Book: https://bit.ly/4aYrDEh Get the 5 Gallon Bucket: https://bit.ly/sdl4sHY Get the Lusketeer Sticker: https://bit.ly/sdl4sHY Subscribe for more exclusive content: https://levilusko.com/hitl-subscribe Time Stamps 0:00:18 – Ketones, cold plunges, and dad-life banter 0:01:23 – Bringing Daphne home: joy, fear, and responsibility 0:06:05 – “Splash radius” and worship in the delivery room 0:20:45 – If the Tree Could Speak: the cross through the tree's eyes 0:40:13 – Grief with hope: “he's not lost—he's found” 0:43:12 – “Look Again”: seeing people as infinitely valuable MVPs
Full Show Notes: bengreenfieldlife.com/drandrew2 In this episode, Dr. Andrew Koutnik returns for part 2 of our deep dive into metabolism and nutrition. We explore why you need far fewer carbohydrates than you think—both during daily life and intense exercise—and how sustained blood glucose levels for brain energy metabolism matter more than muscle glycogen stores. Andrew breaks down the different types of exogenous ketones, debunks liver toxicity concerns, and shares groundbreaking research on ketones for sleep quality and sleep apnea treatment from his NASA astronaut studies. Dr. Andrew Koutnik is a research scientist whose career bridges cutting-edge science, elite performance, and personal experience living with type 1 diabetes for over 17 years. His work focuses on how nutrition, metabolism, and lifestyle can be leveraged to maximize human health, performance, and resilience across diverse conditions—from chronic disease to extreme environments. Episode Sponsors: ZBiotics Pre-Alcohol Probiotic: The world's first genetically engineered probiotic that helps break down the toxic byproduct of alcohol, Zbiotics Pre-Alcohol allows you to enjoy your night out and feel great the next day. Order with the confidence of a 100% money-back guarantee and 15% off your first order at zbiotics.com/BEN15. Young Goose: To experience the transformative power of Young Goose's cutting-edge products, visit younggoose.com and use code BEN10 at checkout to enjoy a 10% discount on your first order. Troscriptions: Explore Troscriptions' revolutionary buccal troche delivery system that bypasses digestion to deliver pharmaceutical-grade, physician-formulated health optimization compounds directly through your cheek mucosa for faster onset and higher bioavailability than traditional supplements. Discover a completely new way to optimize your health at troscriptions.com/BEN or enter BEN at checkout for 10% off your first order. Formula IQ: Recuperate IQ by Formula IQ is a comprehensive copper supplement designed to support mitochondrial energy, iron balance, and metabolic health by pairing bioavailable copper with essential cofactors your body needs for proper utilization, which is especially crucial if you've been under chronic stress or supplementing with high-dose zinc. Try it at formulaiq.com and use code BEN for 10% off.See omnystudio.com/listener for privacy information.
No.1 Health Doctor Benjamin Bikman breaks down keto, insulin resistance, sugar addiction, and calorie counting, and the ONE test that predicts weight gain! Dr Benjamin Bikman is a metabolic scientist and researcher focused on the link between insulin resistance and chronic disease. He is Professor of Cell Biology at Brigham Young University and Co-founder of Insulin IQ. Follow Dr Benjamin: Instagram - https://bit.ly/3MGLKNH X - https://bit.ly/3N6hziZ Website - https://bit.ly/491iGI6 He explains: ◼️Why shrinking fat cells depends on lowering insulin, not eating less ◼️How ketones act as a brain fuel that kills hunger and boosts metabolism ◼️Why constant carb intake traps energy and makes willpower fail ◼️How GLP-1 drugs may worsen muscle loss and long-term metabolic health ◼️Why a fasting insulin test reveals problems years before diabetes [00:00] What Should People Focus on for 2026 When It Comes to Diet? [02:32] What Is Metabolism? [07:18] Why Calorie Counting Doesn't Work [09:57] Ketones and Fat Loss [22:37] How the Liver Decides What to Do With Fat [25:09] Is Keto Sustainable? [27:15] Could Keto Help With Eating Disorders and Sugar Addiction? [30:24] The Effects of Keto on the Heart [32:54] Should You Take Exogenous Ketones? [38:04] Is Keto Suitable for Women? [44:36] The Perfect Diet and Lifestyle for 2026 [51:12] Steve's Ketone Levels After a Keto Shot [57:04] Ads [58:40] Continuing the Perfect Lifestyle for 2026 [59:42] When Not to Do Keto [01:05:48] How Cancers Use Sugar for Energy [01:10:36] Are Vitamins and Supplements Contributing to Obesity? [01:21:19] Thoughts on Ozempic and GLP-1s [01:26:05] Ads [01:32:58] What's the Best Sweetener to Use? [01:34:57] Collagen Peptides [01:37:03] Creatine [01:38:06] How to Get Rid of Stubborn Fat for Good [01:45:23] How Stress Contributes to Weight Gain [01:49:31] Check Your Testosterone Levels [01:51:39] What Tests Can We Do at Home? [01:52:49] If You Could Have One Thing for Life, What Would It Be? The Diary Of A CEO: ◼️Join DOAC circle here - https://doaccircle.com/ ◼️Buy The Diary Of A CEO book here - https://smarturl.it/DOACbook ◼️The 1% Diary is back - limited time only: https://bit.ly/3YFbJbt ◼️The Diary Of A CEO Conversation Cards (Second Edition): https://g2ul0.app.link/f31dsUttKKb ◼️Get email updates - https://bit.ly/diary-of-a-ceo-yt ◼️Follow Steven - https://g2ul0.app.link/gnGqL4IsKKb Sponsors: Pipedrive - https://pipedrive.com/CEO Wispr - Get 14 days of Wispr Flow for free at https://wisprflow.ai/DOAC Ketone - https://ketone.com/STEVEN for 30% off your subscription order
Full Shownotes: https://bengreenfieldlife.com/podcast/495/ In this episode, I take you through a solo Q&A exploring topics like the best sauna practices, the real benefits of walking 7,000 steps a day, and the latest research on gut health treatments—including my personal experience starting a fecal microbiota transplant for chronic issues. How perceived food sensitivities can sometimes create real symptoms, clear up concerns about ketone supplements and liver health, and emphasize the importance of staying active throughout the day. I also mention my biohacking binder and let you know all the resources, studies, and tools I recommend will be linked in the show notes for anyone wanting more details. You’ll gain access to my complete binder of home biohacking tools and gadgets designed to support long-term health and performance (click here to start exploring). Episode Sponsors: IM8: Ditch the cabinet full of supplements—IM8 packs 92 powerhouse ingredients into one delicious scoop for all-day energy, gut health, and cellular support. Go to IM8Health.com and use code BEN for an exclusive gift—fuel your body the right way! Quantum Upgrade: Recent research has revealed that the Quantum Upgrade was able to increase ATP production by a jaw-dropping 20–25% in human cells. Unlock a 15-day free trial with the code BEN15 at quantumupgrade.io. Muse: Muse S Athena combines clinical-grade EEG and fNIRS technology to train your brain in real time while tracking sleep with 86% expert-level accuracy. Get 15% off at choosemuse.com/BENGREENFIELD or use code BENGREENFIELD at checkout. BIOptimizers Magnesium Breakthrough: The 7 essential forms of magnesium included in this full-spectrum serving help you relax, unwind, and turn off your active brain after a long and stressful day, so you can rest peacefully and wake up feeling refreshed, vibrant, and alert. Go to bioptimizers.com/ben and use code ben15 for 15% off any order. LMNT: Everyone needs electrolytes, especially those on low-carb diets, who practice intermittent or extended fasting, are physically active, or sweat a lot. Go to DrinkLMNT.com/BenGreenfield to get a free sample pack with your purchase!See omnystudio.com/listener for privacy information.