Podcasts about mitochondria

Are you exhausted all the time? In this solo episode, Darin breaks down why so many people feel chronically exhausted despite eating clean, exercising, and "doing everything right." He explains how modern life disrupts mitochondrial function, circadian rhythm, stress signaling, and nutrient availability, and why fatigue is not a personal failure, but a biological signal. This episode offers a grounded, practical roadmap to restoring energy by realigning your environment, habits, and daily rhythms with how the body is actually designed to function.     What You'll Learn in This Episode: Why chronic fatigue is exploding—even among healthy, active people How mitochondria do far more than "make energy" The role of circadian rhythm, light exposure, and timing in energy production Why stress, overtraining, and modern lifestyles drain cellular energy How emotional suppression and unexpressed stress affect vitality The difference between forcing energy and allowing energy Simple daily practices that support mitochondrial repair How breathwork, stillness, and social connection restore resilience Why nutrition alone isn't enough without rhythm and recovery How to realign your biology with the modern world     Timecodes 00:00:00 – Welcome to SuperLife and the intention behind this episode 00:00:32 – Sponsor: TheraSage and natural frequency-based healing 00:02:10 – Happy New Year + why this conversation matters now 00:02:37 – Are you exhausted even though you're "doing everything right"? 00:03:26 – The modern energy crisis and rising chronic fatigue 00:04:12 – Why surface-level health advice no longer works 00:04:27 – Mitochondria: more than energy factories 00:04:59 – Circadian misalignment, EMFs, and modern stressors 00:05:36 – Overtraining, stress load, and lack of recovery 00:06:00 – Fatigue as a signal, not a lack of discipline 00:06:18 – How artificial light disrupts internal clocks 00:07:25 – Discipline as alignment with natural rhythms 00:07:36 – Emotional release, primal expression, and energy recovery 00:08:47 – Why "why am I tired all the time?" is exploding online 00:09:24 – The mitochondria as environmental sensors 00:10:06 – Stress signaling, thoughts, and cellular energy flow 00:11:18 – Breathwork and slowing the nervous system 00:12:24 – Social connection and low-stress signaling 00:13:02 – Sponsor: Bite toothpaste and eliminating plastic exposure 00:15:19 – Morning sunlight and circadian priming 00:15:52 – Reducing artificial light at night 00:16:15 – Nutrients that support mitochondrial function 00:17:29 – Sleep timing, consistency, and repair 00:18:20 – Evening routines and melatonin protection 00:19:46 – Small daily steps compound into real energy 00:20:17 – Antioxidants, inflammation, and recovery 00:20:49 – Training smarter, not harder 00:21:31 – Breathwork, sauna, and recovery rituals 00:22:26 – Nutrition, protein, and polyphenols 00:24:37 – Five daily energy takeaways 00:25:24 – Energy is permitted, not forced 00:26:03 – Listening to the body and closing reflections 00:26:49 – SuperLife Patreon and community support     Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien     Thank You to Our Sponsors: Therasage: Go to www.therasage.com and use code DARIN at checkout for 15% off Bite Toothpaste: Go to trybite.com/DARIN20 or use code DARIN20 for 20% off your first order.     Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences     Key Takeaway "Fatigue isn't failure. It's feedback. When your environment, timing, and signals align, your biology remembers how to thrive."     Bibliography/Sources: Ames, B. N. (2006). Low micronutrient intake may accelerate the degenerative diseases of aging through allocation triage. Proceedings of the National Academy of Sciences, 103(47), 17589–17594. https://doi.org/10.1073/pnas.0608757103 Bass, J., & Takahashi, J. S. (2010). Circadian integration of metabolism and energetics. Science, 330(6009), 1349–1354. https://doi.org/10.1126/science.1195668 Gooley, J. J., Chamberlain, K., Smith, K. A., Khalsa, S. B., Rajaratnam, S. M., Van Reen, E., Zeitzer, J. M., Czeisler, C. A., & Lockley, S. W. (2011). Exposure to room light before bedtime suppresses melatonin onset and shortens melatonin duration in humans. The Journal of Clinical Endocrinology & Metabolism, 96(3), E463–E472. https://doi.org/10.1210/jc.2010-2098 Kreher, J. B., & Schwartz, J. B. (2012). Overtraining syndrome: A practical guide. Sports Health, 4(2), 128–138. https://doi.org/10.1177/1941738111434406 Meeusen, R., Duclos, M., Foster, C., Fry, A., Gleeson, M., Nieman, D., Raglin, J., Rietjens, G., Steinacker, J., & Urhausen, A. (2013). Prevention, diagnosis, and treatment of the overtraining syndrome: Joint consensus statement of the European College of Sport Science and the American College of Sports Medicine. European Journal of Sport Science, 13(1), 1–24. https://doi.org/10.1080/17461391.2012.730061 Panda, S. (2016). Circadian physiology of metabolism. Cell Metabolism, 23(6), 1152–1163. https://doi.org/10.1016/j.cmet.2016.06.005 Picard, M., Juster, R. P., & McEwen, B. S. (2014). Mitochondrial allostatic load: Putting the 'gluc' back in glucocorticoids. Nature Reviews Endocrinology, 10(5), 303–310. https://doi.org/10.1038/nrendo.2014.22 Picard, M., & McEwen, B. S. (2018). Psychological stress and mitochondria: A systematic review. Psychosomatic Medicine, 80(2), 126–140. https://doi.org/10.1097/PSY.0000000000000544 Picard, M., McElroy, G. S., & Turnbull, D. M. (2015). Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory, and transcriptional responses to acute psychological stress. Proceedings of the National Academy of Sciences, 112(48), 14920–14925. https://doi.org/10.1073/pnas.1518223112 Reiter, R. J., Rosales-Corral, S., Tan, D. X., Acuna-Castroviejo, D., Qin, L., Yang, S. F., & Xu, K. (2017). Melatonin as a mitochondria-targeted antioxidant: One of evolution's best inventions? Journal of Pineal Research, 62(1), e12394. https://doi.org/10.1111/jpi.12394 Scheer, F. A., Hilton, M. F., Mantzoros, C. S., & Shea, S. A. (2009). Adverse metabolic and cardiovascular consequences of circadian misalignment. Proceedings of the National Academy of Sciences, 106(11), 4453–4458. https://doi.org/10.1073/pnas.0808180106 Straub, R. H. (2017). The brain and immune system prompt energy shortage in chronic inflammation and ageing. Nature Reviews Rheumatology, 13(2), 74–79. https://doi.org/10.1038/nrrheum.2016.213 World Health Organization. (n.d.). Micronutrient deficiencies. World Health Organization. https://www.who.int/health-topics/micronutrients

In this episode, Dr. Datis Kharrazian explores longevity medicine and the hallmarks of aging and disease. How do early signs of loss of resilience—like cognitive decline or changes in physical appearance—offer clues about our biological age? What can cutting-edge studies, such as the Dunedin Longitudinal Study, teach us about predicting poor aging trajectories and preventing chronic diseases like cardiovascular issues and cancer, before they silently take hold?Dr. Kharrazian uncovers the mechanisms underlying tissue degeneration, explores why resilience is central to healthy aging, and explains how functional medicine clinicians can use biomarkers and in-depth assessments to help shift morbidity later in life. Whether you're a healthcare practitioner, a nutrition enthusiast, or facing chronic health challenges, this episode bridges the gap between complex science and actionable steps you can implement right now.Learn functional longevity strategies from Dr. Datis Kharrazian. Discover how to use personalized nutrition, diet, and lifestyle approaches to optimize healthspan. Enroll in the Longevity Mastery Program at: https://pages.kharrazianinstitute.com/longevityFor patient-oriented functional medicine courses, visit https://drknews.com/online-courses/For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/00:00 "Longevity, Wellness, and Disease"03:51 "Pace and Markers of Aging"09:02 "Aging Mechanisms and Disease Links"13:33 Aging, Resilience, and Clinical Outcomes14:52 "Hallmarks of Aging Explained"20:11 "Aging Tissues and Inflammation"22:18 Mitochondria, Aging, and Vascular Health25:59 Cancer Warning Signs32:21 "Aging's Role in Cancer Progression"33:13 "Functional Health Solutions Podcast"Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

We're back with another episode in a series of highly vetted companies that I love sharing with my community. Today, I'm joined by Forrest Smith, the co-founder and CEO of Kineon. A dynamic entrepreneur with an infectious enthusiasm for his work, Forrest reads and writes fluent Chinese, lives in Mexico, and brings over 20 years of experience building and scaling successful startups. His work at Kineon reflects his optimism and innovative approach in the field of health and wellness technology. In our conversation, we explore what red light therapy (photobiomodulation) is and its cellular and mitochondrial effects. We unpack the benefits of methylene blue, the impact of photobiomodulation on joint pain and thyroid health, and specific contraindications. We also discuss red light therapy and the gut hormone access, peptides, recovery toolkits, and female-centric research related to infertility, PCOS, endometriosis, thyroid health, and more. This is one of those conversations you will likely want to listen to more than once. Be sure to check the show notes for a special offer from Kineon, exclusively for my listeners. IN THIS EPISODE, YOU WILL LEARN: What is red light therapy? How red light therapy supports the body at the cellular level, particularly during the aging process How methylene blue enhances the effects of red light therapy The value of photobiomodulation for treating chronically inflamed joints and muscle tissue How local inflammation in the joints impacts gut health The benefits of red light therapy for female-specific pathologies, such as endometriosis, hypothyroidism, and dysmenorrhea The way that red light therapy works in combination with stem cell treatments, PRP, and extracorporeal shock wave therapy Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow  Cynthia's Menopause Gut Book is on presale now! Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Connect with Forrest Smith Kineon Kineon Labs on Instagram We're giving away TWO Kineon Move+ Pro devices (worth $499 each!) Want to enter? Leave a review of the Everyday Wellness podcast in English on Apple Podcasts or Spotify.  Take a screenshot of your review. Email the screenshot and one reason why you'd like to win to podcast@cynthiathurlow.com (You must live in the U.S. to enter.)

Send us a textCellular metabolism, mitochondrial health, and the roles of diet and environment in metabolic health, fetal & child development, and Alzheimer's.TOPICS DISCUSSED:Cellular growth vs. burning: Cells alternate between growing (using glucose for building blocks in low-oxygen environments) and burning (generating ATP in mitochondria with oxygen); dysregulation leads to metabolic issues.Key regulatory enzymes: PI3 kinase imports glucose, AMP kinase builds mitochondria, and mTOR drives cell division; their synchronization determines healthy modes, while desynchronization causes diseases.Fructose as a dose-dependent mitochondrial toxin: High fructose intake inhibits AMP kinase, reducing mitochondrial function and diverting energy to fat storage; it is dose-dependent, like alcohol, and unnecessary in the diet.Obesogens & endocrine disruptors: Chemicals like tributyltin (TBT) alter gene expression across generations, promoting obesity unrelated to calories; modern exposures increase reactive oxygen species (ROS), burdening cells.Fetal & neonatal development: Maternal diet, especially high sugar or formula feeding, can cause neonatal obesity and fatty liver; breastfeeding supports proper jaw development and oxygen intake.Brain metabolism & Alzheimer's: The brain's high energy needs make it vulnerable to mitochondrial issues and ROS; energy deficits from diet, stress, and toxins lead to synapse loss and inflammation, treatable via prevention.ROS & health: Mitochondria produce ROS as a byproduct of ATP generation; excess from diet or environment causes damage, but antioxidants and lifestyle can mitigate risks.PRACTICAL TAKEAWAYS:Limit added sugars in your diet to reduce mitochondrial stress and ROS, focusing on whole foods over ultra-processed items for better metabolic health.Prioritize breastfeeding for infants when possible to support proper physical development and reduce future metabolic risks.Incorporate regular exercise and social activities to manage stress and boost brain-protective factors like BDNF, aiding neurodegeneration prevention.Get adequate sleep to regulate cortisol and maintain cellular energy balance, helping prevent brain fog and chronic diseases.ABOUT THE GUEST: Robert Lustig, MD is a pediatric endocrinologist and Professor Emeritus at the University of California, San Francisco, with a background in neuroendocrinology and obesity research.*Not medical advice.Support the showAffiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts

In this expansive and deeply honest conversation, Darin sits down with Gregory Schwartz for a wide-ranging exploration of awakening, ecology, food systems, energy, consciousness, and what it truly means to live in right relationship with the planet and ourselves. What begins as a conversation about athletic identity and environmental travel unfolds into a profound dialogue on political ecology, spiritual awakening, mitochondrial intelligence, community-scale solutions, and the collapse of outdated belief systems. This episode bridges the scientific, the spiritual, and the deeply human—offering a grounded yet visionary roadmap for creating a future where health, sovereignty, and connection replace extraction, disconnection, and burnout.     What You'll Learn in This Episode How early athletic identity, injury, and discipline shaped Greg's lifelong path Why travel and "ground-truthing" reality changes how we see the world The concept of the "Planet Doctor" and speaking on behalf of Earth Why data alone doesn't change behavior—and why the heart must lead How food systems, soil health, and gut health are inseparably linked The real reasons environmental solutions stall despite available money and technology Why community-scale action is the missing link between individual and government change How regenerative food systems ripple into health, ecology, and social cohesion The dangers of hyper-productivity and the loss of rest, recovery, and contemplation Why mitochondria are not just powerhouses—but listeners and conductors of energy What spiritual awakening actually feels like—and why it can be destabilizing The collapse of identity as a necessary step toward integration The difference between being a messenger and being the message How awakenings mature from chaos into discipline, embodiment, and service Why optimism comes from living examples, not abstract ideology How small, aligned actions create resonance fields that attract new realities     Timecodes 00:00 – Athletic roots, injury, and the pivot into physiology & nutrition 03:00 – Travel, environmental exposure, and seeing reality beyond data 07:00 – Political ecology, capitalism, and the illusion of separation from nature 12:30 – Food systems, soil health, and gut microbiome parallels 16:00 – Regenerative agriculture, working with farmers, and nuance over dogma 20:00 – Community-scale solutions: food, energy, microgrids, and localization 24:00 – Burnout culture, productivity addiction, and missing rest cycles 27:00 – Mitochondria, flow state, and the intelligence of the cell 30:00 – Spiritual awakening: lightning bolts, breakdowns, and integration 35:00 – Heaven, hell, and altered states as present-moment realities 39:00 – Discipline vs. chaos: maturing the awakening process 44:00 – Being the message vs. delivering the message 49:00 – Embodiment, purpose, and integrating spirituality into real life 55:00 – System collapse, courage, and rebuilding new realities 01:00:00 – Hope, optimism, and why examples matter more than arguments 01:05:00 – Creating resonance through aligned action and community     Find More From Gregory Schwartz Political ecology research and teaching Environmental systems, food sovereignty, and regenerative frameworks Community-scale energy and food solutions Writing and speaking on consciousness, awakening, and integration     Thank You to Our Sponsors Truniagen: Go to www.truniagen.com and use code DARIN20 at checkout for 20% off Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout.     Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien     Find More from Gregory Schwartz Website: theplanetdoctor.com Instagram: @theplanetdoctor Try Greg's Free Masterclass by signing up here!     Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences     Key Takeaway "The systems don't change because we lack solutions—they don't change because we haven't changed our relationship to ourselves, to nature, and to each other. When that shifts, everything else follows."  

Episode 210: Heat Stroke BasicsWritten by Jacob Dunn, MS4, American University of the Caribbean. Edits and comments by Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice. Definition:Heat stroke represents the most severe form of heat-related illness, characterized by a core body temperature exceeding 40°C (104°F) accompanied by central nervous system (CNS) dysfunction. Arreaza: Key element is the body temperature and altered mental status. Jacob: This life-threatening condition arises from the body's failure to dissipate heat effectively, often in the context of excessive environmental heat load or strenuous physical activity. Arreaza: You mentioned, it is a spectrum. What is the difference between heat exhaustion and heat stroke? Jacob: Unlike milder heat illnesses such as heat exhaustion, heat stroke involves multisystem organ dysfunction driven by direct thermal injury, systemic inflammation, and cytokine release. You can think of it as the body's thermostat breaking under extreme stress — leading to rapid, cascading failures if not addressed immediately. Arreaza: Tell us what you found out about the pathophysiology of heat stroke?Jacob: Pathophysiology: Under normal conditions, the body keeps its core temperature tightly controlled through sweating, vasodilation of skin blood vessels, and behavioral responses like seeking shade or drinking water. But in extreme heat or prolonged exertion, those mechanisms get overwhelmed.Once core temperature rises above about 40°C (104°F), the hypothalamus—the brain's thermostat—can't keep up. The body shifts from controlled thermoregulation to uncontrolled, passive heating. Heat stroke isn't just someone getting too hot—it's a full-blown failure of the body's heat-regulating system. Arreaza: So, it's interesting. the cell functions get affected at this point, several dangerous processes start happening at the same time.Jacob: Yes: Cellular Heat InjuryHigh temperatures disrupt proteins, enzymes, and cell membranes. Mitochondria start to fail, ATP production drops, and cells become leaky. This leads to direct tissue injury in vital organs like the brain, liver, kidneys, and heart.Arreaza: Yikes. Cytokines play a big role in the pathophysiology of heat stroke too. Jacob: Systemic Inflammatory ResponseHeat damages the gut barrier, allowing endotoxins to enter the bloodstream. This triggers a massive cytokine release—similar to sepsis. The result is widespread inflammation, endothelial injury, and microvascular collapse.Arreaza: What other systems are affected?Coagulation AbnormalitiesEndothelial damage activates the clotting cascade. Patients may develop a DIC-like picture: microthrombi forming in some areas while clotting factors get consumed in others. This contributes to organ dysfunction and bleeding.Circulatory CollapseAs the body shunts blood to the skin for cooling, perfusion to vital organs drops. Combine that with dehydration from sweating and fluid loss, and you get hypotension, decreased cardiac output, and worsening ischemia.Arreaza: And one of the key features is neurologic dysfunction.Jacob: Neurologic DysfunctionThe brain is extremely sensitive to heat. Encephalopathy, confusion, seizures, and coma occur because neurons malfunction at high temperatures. This is why altered mental status is the hallmark of true heat stroke.Arreaza: Cell injury, inflammation, coagulopathy, circulatory collapse and neurologic dysfunction. Jacob: Ultimately, heat stroke is a multisystem catastrophic event—a combination of thermal injury, inflammatory storm, coagulopathy, and circulatory collapse. Without rapid cooling and aggressive supportive care, these processes spiral into irreversible organ failure.Background and Types:Arreaza: Heat stroke is part of a spectrum of heat-related disorders—it is a true medical emergency. Mortality rate reaches 30%, even with optimal treatment. This mortality correlates directly with the duration of core hyperthermia. I'm reminded of the first time I heard about heat stroke in a baby who was left inside a car in the summer 2005. Jacob: There are two primary types: -nonexertional (classic) heat stroke, which develops insidiously over days and predominantly affects vulnerable populations like children, the elderly, and those with chronic illnesses during heat waves; -exertional heat stroke, which strikes rapidly in young, otherwise healthy individuals, often during intense exercise in hot, humid conditions. Arreaza: In our community, farm workers are especially at risk of heat stroke, but any person living in the Central Valley is basically at risk.Jacob: Risk factors amplify vulnerability across both types, including dehydration, cardiovascular disease, medications that impair sweating (e.g., anticholinergics), and acclimatization deficits. Notably, anhidrosis (lack of sweating) is common but not required for diagnosis. Hot, dry skin can signal the shift from heat exhaustion to stroke. Arreaza: What other conditions look like heat stroke?Differential Diagnosis:Jacob: Presenting with altered mental status and hyperthermia, heat stroke demands a broad differential to avoid missing mimics. -Environmental: heat exhaustion, syncope, or cramps. -Infectious etiologies like sepsis or meningitis must be ruled out. -Endocrine emergencies such as thyroid storm, pheochromocytoma, or diabetic ketoacidosis (DKA) can overlap. -Neurologic insults include cerebrovascular accident (CVA), hypothalamic lesions (bleeding or infarct), or status epilepticus. -Toxicologic culprits are plentiful—sympathomimetic or anticholinergic toxidromes, salicylate poisoning, serotonin syndrome, malignant hyperthermia, neuroleptic malignant syndrome (NMS), or even alcohol/benzodiazepine withdrawal. When it comes to differentials, it is always best to cast a wide net and think about what we could be missing if this is not heat stroke. Arreaza: Let's say we have a patient with hyperthermia and we have to assess him in the ER. What should we do to diagnose it?Jacob: Workup:Diagnosis is primarily clinical, hinging on documented hyperthermia (>40°C) plus CNS changes (e.g., confusion, delirium, seizures, coma) in a hot environment. Arreaza: No single lab confirms it, but targeted testing allows us to detect complications and rule out alternative diagnosis. Jacob: -Start with ECG to assess for dysrhythmias or ischemic changes (sinus tachycardia is classic; ST depressions or T-wave inversions may hint at myocardial strain). -Labs include complete blood count (CBC), comprehensive metabolic panel (electrolytes, renal function, liver enzymes), glucose, arterial blood gas, lactate (elevated in shock), coagulation studies (for disseminated intravascular coagulation, or DIC), creatine kinase (CK) and myoglobin (for rhabdomyolysis), and urinalysis. Toxicology screen if history suggests. Arreaza: I can imagine doing all this while trying to cool down the patient. What about imaging?-Imaging: chest X-ray for pulmonary issues, non-contrast head CT if neurologic concerns suggest edema or bleed (consider lumbar puncture if infection suspected). It is important to note that continuous core temperature monitoring—via rectal, esophageal, or bladder probe—is essential, not just peripheral skin checks. Arreaza: TreatmentManagement:Time is tissue here—initiate cooling en route, if possible, as delays skyrocket morbidity. ABCs first: secure airway (intubate if needed, favoring rocuronium over succinylcholine to avoid hyperkalemia risk), support breathing, and stabilize circulation. -Remove the patient from the heat source, strip clothing, and launch aggressive cooling to target 38-39°C (102-102°F) before halting to prevent rebound hypothermia. -For exertional cases, ice-water immersion reigns supreme—it's the fastest method, with immersion in cold water resulting in near-100% survival if started within 30 minutes. -Nonexertional benefits from evaporative cooling: mist with tepid water (15-25°C) plus fans for convective airflow. -Adjuncts include ice packs to neck, axillae, and groin; -room-temperature IV fluids (avoid cold initially to prevent shivering); -refractory cases, invasive options like peritoneal lavage, endovascular cooling catheters, or even ECMO. -Fluid resuscitation with lactated Ringer's or normal saline (250-500 mL boluses) protects kidneys and counters rhabdomyolysis—aim for urine output of 2-3 mL/kg/hour. Arreaza: What about medications?Jacob: Benzodiazepines (e.g., lorazepam) control agitation, seizures, or shivering; propofol or fentanyl if intubated. Avoid antipyretics like acetaminophen. For intubation, etomidate or ketamine as induction agents. Hypotension often resolves with cooling and fluids; if not, use dopamine or dobutamine over norepinephrine to avoid vasoconstriction. Jacob: What IV fluid is recommended/best for patients with heat stroke?Both lactated Ringer's solution and normal saline are recommended as initial IV fluids for rehydration, but balanced crystalloids such as LR are increasingly favored due to their lower risk of hyperchloremic metabolic acidosis and AKI. However, direct evidence comparing the two specifically in the setting of heat stroke is limited. Arreaza: Are cold IV fluids better/preferred over room temperature fluids?Cold IV fluids are recommended as an adjunctive therapy to help lower core temperature in heat stroke, but they should not delay or replace primary cooling methods such as cold-water immersion. Cold IV fluids can decrease core temperature more rapidly than room temperature fluids. For example, 30mL/kg bolus of chilled isotonic fluids at 4 degrees Celsius over 30 minutes can decrease core temperature by about 1 degree Celsius, compared to 0.5 degree Celsius with room temperature fluids. Arreaza: Getting cold IV sounds uncomfortable but necessary for those patients. Our favorite topic.Screening and Prevention:-Heat stroke prevention focuses on public health and individual awareness rather than routine testing. -High-risk groups—elderly, children, athletes, laborers, or those on impairing meds—should acclimatize gradually (7-14 days), hydrate preemptively (electrolyte solutions over plain water), and monitor temperature in exertional settings. -Communities during heat waves need cooling centers and alerts. -For clinicians, educate patients with CVD or obesity about early signs like dizziness or nausea. -No formal "screening" exists, but vigilance in EDs during summer surges saves lives. -Arreaza: I think awareness is a key element in prevention, so education of the public through traditional media like TV, and even social media can contribute to the prevention of this catastrophic condition.Jacob: Ya so heat stroke is something that should be on every physician's radar in the central valley especially in the summer time given the hot temperatures. Rapid recognition is key. Arreaza: Thanks, Jacob for this topic, and until next time, this is Dr. Arreaza, signing off.Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! References:Gaudio FG, Grissom CK. Cooling Methods in Heat Stroke. J Emerg Med. 2016 Apr;50(4):607-16. doi: 10.1016/j.jemermed.2015.09.014. Epub 2015 Oct 31. PMID: 26525947. https://pubmed.ncbi.nlm.nih.gov/26525947/.Platt, M. A., & LoVecchio, F. (n.d.). Nonexertional classic heat stroke in adults. In UpToDate. Retrieved September 7, 2025, from https://www.uptodate.com/contents/nonexertional-classic-heat-stroke-in-adults. (Key addition: Emphasizes insidious onset in at-risk populations and the role of urban heat islands in exacerbating classic cases.) Heat Stroke. WikEM. Retrieved December 3, 2025, from https://wikem.org/wiki/Heat_stroke. (Key additions: Details on cooling rates for immersion therapy, confirmation that anhidrosis is not diagnostic, and fluid titration to urine output for rhabdomyolysis prevention.)Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/. 

Send us a textMitochondrial dysfunction affects overall energy production and is linked to chronic conditions including fatigue, brain fog, and inflammatory disorders. We explore how to support cellular energy through nutrition, lifestyle, and mindset transformation.• Mitochondria are the cell's powerhouse, affecting metabolism, oxidative stress, and cellular signaling• Poor diet, medications, toxins, chronic stress, and inadequate exercise can disrupt mitochondrial function• Key supplements for energy support include CoQ10, alpha-lipoic acid, acetyl-L-carnitine, magnesium, and B vitamins• Lifestyle interventions like intermittent fasting, red light therapy, grounding, and quality sleep improve energy production• Heavy metals including lead, arsenic, and mercury can directly poison mitochondria and decrease energy• Energy production requires proper macronutrients (carbs, fats, proteins) and micronutrients (vitamins, minerals, cofactors)• The "10 A's of Transformation" provide a holistic framework for energy enhancement: Awareness, Action, Alignment, Accountability, Acceptance, Authenticity, Attention, Adaptability, Appreciation, and Abundance Support the show Sponsor Affiliates Empowering Your Health https://www.atecam.com/ Get YOUR Own Joburg Protein Snacks Discount Code: Damaris15 Or Damaris18 Feeling need to Lose Weight & Become metabolically Healthy GET METABOLIC COURSE GLP 1 REseT This course is designed for individuals looking to optimize their metabolic health through integrative and functional medicine approaches. Whether you're on a GLP-1 medication or seeking natural ways to enhance your metabolic function, this course provides actionable steps, expert insights, and a personalized roadmap sustainable wellness. Are you feeling stressed, tired, or Metabolism imbalanced? Take advantage of our free mindful steps to help improve your well-being.ENJOY ONE OF our Books Mindful Ways Health Wealth & Life https://stan.store/Mindfullyintegrative Join Yearly membership ALL IN ONE FUNCTION HEALTH Ask Us for help...

Podcast Description: The Cellular Breakthrough That Changed How I See Chronic IllnessSchedule a Discovery Zoom call to see if we can help you!Welcome to today's episode with Doctor Hugh. In this podcast, I share a simple but powerful idea that has helped many of my clients heal faster than ever before.This is about cell energy, sunlight, and how your body makes power to heal.What This Episode Is AboutA cellular breakthrough that changed how I treat chronic illnessWhy many sick people are still not getting betterHow the body uses light like plants use sunlightWhy energy comes before detoxOne affordable tool that helps fragile and very sick people healWho This Episode Is ForIf you struggle with:FibromyalgiaBrain fogIBS or gut problemsDamage from antibioticsChronic fatigueTrouble thinking or memory lossThis episode is for you.The Big Idea: Your Body Uses LightPlants use sunlight to grow foodThis process is called photosynthesisYour body works in a similar waySpecial light waves help your cells make energyWhen you don't get enough of these light waves:Cells slow downMitochondria stop working wellHealing becomes very hardWhy Chronic Illness HappensMany sick people are low in healthy light exposureModern life keeps us indoorsYour cells become energy starvedLow energy leads to pain, inflammation, and diseaseWhy Infrared Light MattersMost sunlight energy is invisibleOnly a small part is visible lightInfrared light makes up over half of the sun's energyThis light goes deep into the bodyDeep light helps:Mitochondria make energyCells repair themselvesThe body heal without stressNot All Heat Is the SameThis is not about sweatingSick people should not push detoxThe goal is gentle energy supportThe wavelength does the workWhy I Recommend an Infrared Sauna BlanketSkin-to-skin contact gives deep penetrationWorks without extreme heatSafe for very fragile peopleAffordable and easy to use at homeKey benefits:Supports energy productionHelps cells heal naturallyNo harsh detox reactionsUnderstanding Infrared Light (Simple Version)Near infrared = closer to visible lightMid infrared = middle rangeFar infrared = deepest penetrationFar infrared goes deepest, reaching:CellsMitochondriaCell membranesThat's why it matters most for chronic illness.Why Deeper Is BetterDeeper light reaches energy factories in cellsEnergy leads to repairRepair leads to healingJust like sunlight feeds plants:Infrared light feeds your cellsReal ResultsSince focusing on energy first:Clients heal fasterProgress is smootherLess crashing and setbacksBetter long-term recoveryFinal MessageYou do not need to suffer.You need:The right energyThe right guidanceA plan made for your bodyNext StepsVisit my websiteSchedule a callGet a guided plan made just for youHealing

Dr. Lara Briden challenges everything you think you know about metabolism, revealing why energy—not weight—is the true marker of metabolic health. This conversation explores how modern life has pushed our physiology into states it was never designed for, and offers a compassionate, science-based approach to understanding your body as a logical system rather than a problem to fix.GUEST INFORMATION:Name: Dr. Lara BridenTitle/Credentials: Naturopathic doctor, author, former evolutionary biology researcher Background: Has peer-reviewed publications and thesis in evolutionary biology, specializes in women's health with focus on centering female physiology as normal mammalian function EPISODE HIGHLIGHTS:Evolutionary Biology FrameworkDr. Briden explains how her background in evolutionary biology informs her medical practice, viewing women's bodies as logical systems that make biological sense Menopause as Evolutionary AdvantageDiscussion of how menopause evolved as a survival advantage, with post-reproductive women being essential for family group survival Debunking the Willpower MythChallenges the narrative that metabolic issues are about eating too much and exercising too little The Asthma AnalogyExplains why telling people to "just lose weight" is like telling someone with asthma to "just breathe better" Environmental FactorsDetails how environmental toxins, gut microbiome changes, and epigenetics contribute to metabolic dysfunction across species and generations Energy as Metabolic MarkerExplains metabolic flexibility and how the body should preferentially burn fat in fasting states Blood Sugar CrashesDiscusses how insulin resistance often presents as reactive hypoglycemia rather than high blood sugar Seed Oils DiscussionDr. Briden shares her perspective on high-dose omega-6 oils as metabolically problematic signaling molecules Nervous System and MetabolismExplores how the autonomic nervous system significantly impacts insulin sensitivity and metabolic rate Key Metabolic NutrientsDiscuss essential nutrients for metabolic health: magnesium, taurine, choline, inositol, and glycine, historically obtained from organ meats Mitochondria as MastersFascinating discussion of mitochondria as dynamic cellular powerhouses affected by emotions and social activity Lab Testing SimplifiedProvides practical lab markers for insulin resistance: ALT levels, ALT to AST ratio, and triglycerides RESOURCES MENTIONED:Metabolism Repair For Women, by Dr. BridenPeriod Repair Manual (previous book) Potential upcoming cookbook collaboration KEY TAKEAWAYS:Metabolism problems often come before weight gain, not after—it's about insulin resistance first Energy levels and satiety between meals are better indicators of metabolic health than body weight Environmental factors including toxins, processed oils, and gut dysfunction are major contributors to metabolic issues The body has a complex system that can't be micromanaged—focus on removing obstacles and supporting overall health Simple lab tests (ALT, triglycerides) can reveal insulin resistance more effectively than complex testing Website: https://www.larabriden.com/CALL TO ACTION:Subscribe to the One Thing Podcast for more conversations that challenge conventional health wisdom and center biology over blame. Share this episode with someone who's been struggling with metabolic health issues—these insights could be exactly what they need to hear.

Have you ever said, "I just don't feel like myself anymore" — even though your labs look normal? In this episode of the Health Fix Podcast, Dr. Jannine Krause breaks down why inflammation starts in the brain, how it drives fatigue, brain fog, cravings, hormone imbalance, and accelerated aging — and why 2026 is the year to stop suppressing symptoms and start correcting root causes. Inflammation isn't just a body problem. It's a brain health issue first. Your brain uses 20% of your daily calories, and when inflammation is present, it shifts into defensive mode, not performance mode. That's when clarity disappears, energy crashes, and nothing feels like it's working anymore.

This solo masterclass on oxalates explains why many people who eat clean still struggle with joint pain, kidney stones, fatigue, brain fog, and chronic inflammation. You'll learn how oxalates behave very differently from other plant compounds like lectins, phytates, and salicylates. Unlike those compounds, oxalates physically bind minerals and form microscopic crystals that can lodge in tissues, damage mitochondria, and accumulate over time. This episode will change how you think about superfoods, clean eating, and long term human performance. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey walks you through the real science of oxalates using decades of self experimentation, functional medicine research, and hands on biohacking. As the founder of the biohacking movement, Dave has tested fasting, ketosis, carnivore strategies, supplements, nootropics, sleep optimization protocols, and metabolic interventions to uncover what actually improves resilience, neuroplasticity, and mitochondrial function without unnecessary damage. In this masterclass, you'll learn why oxalates cause problems even when digestion seems fine, why symptoms can show up in joints, kidneys, nerves, skin, and old injuries, and why reducing oxalates too fast can make you feel worse before you feel better. Dave explains oxalate dumping, candida driven oxalate overload, microbiome interactions, and why foods like spinach, almonds, cacao, and green smoothies often backfire over time. He also shares practical ways to lower your oxalate load safely, support mineral balance, and protect your metabolism and brain using a Smarter Not Harder approach. This episode is for you if you eat “healthy” but still feel off, deal with unexplained pain or inflammation, or want to improve longevity, brain optimization, sleep, and human performance without extreme restriction. You'll Learn: • Why oxalates are different from lectins, phytates, and other plant toxins • How oxalates drain minerals and damage mitochondria • What oxalate dumping feels like and how to avoid it • Which superfoods cause the biggest problems and what to replace them with • How hydration, minerals, and supplements affect oxalate clearance • Why oxalates accelerate aging and tissue stiffness over time • Practical biohacking strategies to protect longevity and human performance Thank you to our sponsors! -ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. -Branch Basics | Get 15% off Branch Basics with the code DAVE15 at https://branchbasics.com/DAVE15. -BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 to save 20% off your first order of PerfectAmino. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: oxalates, oxalic acid, biohacking oxalates, oxalate dumping, plant toxins explained, lectins vs oxalates, phytates and mineral absorption, anti-nutrients, superfoods controversy, clean eating problems, kidney stones oxalates, joint pain inflammation, mineral depletion, calcium oxalate crystals, metabolism dysfunction, brain fog causes, neuroplasticity and inflammation, longevity nutrition, anti-aging nutrition, functional medicine oxalates, supplements for oxalates, hydration and kidney health, urinary pH balance, candida and oxalates, microbiome and oxalates, fasting and oxalates, ketosis and oxalates, carnivore diet transition, human performance nutrition, sleep optimization inflammation, nootropics and brain optimization, Dave Asprey oxalates Resources: • Join Our New Low-Oxalate Challenge! https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 – Trailer 1:25 – Introduction 3:18 – What Are Oxalates 5:40 – Oxalates vs Other Plant Toxins 7:18 – Oxalate Sources and Chemistry 9:17 – Kidney Stones and Crystal Formation 10:19 – Oxalate Dumping Explained 12:03 – System Level Effects 14:54 – Inflammation, Mitochondria, and Aging 16:56 – Who Should Pay Attention 19:32 – High Oxalate Foods 24:56 – Smart Food Swaps 27:22 – Exercise and Hydration 29:07 – Clearing Oxalates Safely 31:01 – Summary and Key Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This week I interviewed the Founder & CEO of Touchstone Essentials - Eddie Stone! Eddie's background working directly with everyday people on practical detox solutions, combined with his experience leading one of the most trusted clean supplement brands, gives him a unique perspective on the real-world challenges people face when trying to improve their health. We discussed the importance of sourcing when it comes to ingredients for health and wellness products along with:- Supporting Detox for your Cells- Power of Zeolites- How Environmental Factors affect your Healthand his one tip to get your body back to what it once was!Product Special: https://getleaneatclean.thegoodinside.com/special-offer-telo-vital-lp-------FREE Nutrition Cheatsheets:https://brian-getleaneatclean.beehiiv.com/subscribeClick to book a FREE 15 minute consult with Brian:https://calendly.com/bdgryn/15min------------Interested in Upgrading your Mitochondria, Improving Energy and Sleep! Check out Troscriptions: https://bit.ly/4ik5kK5Use Discount Code for 10% OFF: EATCLEAN----Watch Get Lean Eat Clean podcast video episodes on YouTube!YouTube.com/@briangryn3680----B.rad Whey Protein Isolate Superfuel:The Best Protein on The Planet! Available in Two Delicious Flavors: Vanilla Bean and Cocoa BeanUse Coupon Code glec10off for 10% off your order!https://a.co/d/731gssV----My favorite health bars with clean ingredients!https://www.eatprima.com/BRIAN6816310% OFF with this link!

Cancer, cardiovascular disease, diabetes, mold toxicity, parasites, and chronic illness are often treated as separate problems—but what if they all stem from the same root cause? David DeHaas, founder of Living Waters Wellness Center, sits down with Alicia Hickson, PA-C, founder of Rama Health, to explore why cancer is not primarily a genetic disease, but a metabolic and mitochondrial disorder driven by inflammation, toxins, mold exposure, parasites, blood sugar dysregulation, emotional trauma, and impaired detoxification pathways.Drawing from the groundbreaking research of Dr. Thomas Seyfried, Alicia explains how damaged mitochondria alter cellular energy production, creating an internal environment where cancer and chronic disease can thrive. This conversation challenges the conventional genetic theory of cancer and reframes healing through the lens of terrain medicine.Throughout the episode, David and Alicia connect the dots between:Mitochondrial dysfunction and cancer metabolismMold toxicity, candida, yeast, and immune system overloadParasites and chronic inflammationEmotional trauma, unforgiveness, and limbic system dysregulationConstipation, lymphatic congestion, and impaired detox pathwaysWhy genetics account for only a small percentage of disease riskWhy conventional medicine often misses root causesWhen integrative and conventional medicine work best togetherDavid shares compelling real-world cases from Living Waters Wellness Center, including parasite cleansing, colon hydrotherapy, emotional release, and rapid shifts in tumor presentation—demonstrating how healing accelerates when the body's internal terrain is restored.Alicia also breaks down advanced clinical tools and therapies, including:Circulating tumor cell testing for cancer monitoringHormone metabolism and estrogen detox pathways (DUTCH testing)Mold and mycotoxin testing strategiesHyperthermia therapy, mistletoe therapy, and immune modulationWhy maintaining remission is just as important as treating cancerThis episode is essential listening for anyone who has been told, “There's nothing more we can do,” aSupport the show Ready for your healing journey?Visit our website: www.LivingWatersCleanse.com Or give us a call at: (208) 378-9911Stem Cell Activation Patches:www.StemCellPatch.netGet your Supplements and Natural Body Products Here:www.livingwaterscleanse.com/supplementsQI-Shield EMF Devices:Protect your whole home or office with a touric shield from EMF's. 1. QI Shield Covers 16'x16' 2. QI Home Covers 50' x 50' 3. QI Max Covers 250'x250'Click on link and enter Livingwaters in discount code section during checkout Magnesium Soaks:Follow us on our socials: Living Waters Wellness CenterBitChute: www.bitchute.com/livingwaterswellnessRumble: www.rumble.com/l...

In this solo episode of The SuperLife Podcast, Darin Olien dives deep into the true biology of energy—not motivation, not stimulants, not willpower, but the mitochondria themselves. Inspired by a groundbreaking conversation between Dr. Andrew Huberman and Dr. Martin Picard, Darin reframes energy as an emergent property of how we live, not just what we eat or how much we sleep. This episode explores how mitochondria act as signal translators, listening to your food, stress, sleep, movement, emotions, purpose, and environment—and turning those signals into either vitality or depletion. Darin connects cutting-edge mitochondrial science with real-world practices around recovery, meaningful stress, consistency, connection, and alignment, showing how true longevity and resilience are built at the cellular level.     What You'll Learn in This Episode 00:00  – Welcome to SuperLife & the mission of sovereignty and vitality 00:32 – Thera Sage sponsor: family-built healing tech & red light 02:10 – Why this episode is different: diving into cellular energy 02:42 – Inspiration from Huberman & Picard's mitochondria conversation 03:11 – Rethinking mitochondria: not just ATP, but information processors 04:03 – Energy as potential for change, not calories or fuel 04:39 – How thoughts, emotions, food, and stress shape energy 05:05 – Energy is dynamic, adaptive, and responsive to how you live 06:02 – Mitochondria as signal integrators: sleep, hormones, purpose, connection 06:50 – Mitochondria as antennas, not factories 07:16 – Translating life experience into biological energy 08:09 – Why we don't feel "energy," we feel energy flow 08:53 – Flow states, purpose, and why passion creates vitality 09:32 – Different organs, different mitochondrial roles 10:26 – Why energy optimization is not one-size-fits-all 10:49 – Energy resistance: the hidden cause of fatigue and burnout 11:47 – Chronic stress, poor sleep, and ultra-processed food as energy blockers 12:12 – Why recovery is non-negotiable for longevity 12:20 – Caldera Lab sponsor: clean, performance-driven skincare 14:20 – The danger of constant output without recovery 14:45 – Sleep as a mitochondrial reset and repair system 15:40 – Exercise, adaptation, and why recovery completes the signal 16:22 – Intentional stress vs. chronic stress 17:29 – Food as information, not just fuel 18:05 – Time-restricted eating, fresh food, and metabolic signaling 18:27 – Meaning, purpose, and emotional states as cellular inputs 19:23 – Mitochondria, aging, and the potential reversibility of decline 20:06 – SuperLife framework: alignment over optimization 20:37 – Consistency beats intensity at the cellular level 21:19 – Stable rhythms: sleep, nourishment, hydration, movement 21:45 – Stillness, meditation, and parasympathetic repair 22:35 – Growth requires both resistance and recovery 24:44 – Connection, community, and loneliness as biological signals 25:27 – Eliminating fatal conveniences to restore vitality 26:02 – Your mitochondria are listening—change the signals 26:21 – Honoring Huberman & Picard's contribution to human health 27:12 – Energy flow as the foundation of a SuperLife 28:11 – Closing reflections and invitation to apply this work     Thank You to Our Sponsors Therasage: Go to www.therasage.com and use code DARIN at checkout for 15% off Caldera Lab: Experience the clinically proven benefits of Caldera Lab's clean skincare regimen and enjoy 20% off your order by visiting calderalab.com/darin and using code DARIN at checkout.     Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien     Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences     Key Takeaway "Your mitochondria are not broken. They are responding perfectly to the signals you give them. Change the signals, and your energy, resilience, and life will follow."     Bibliography & Sources Here is the bibliography based on the sources referenced in the document, formatted with direct links to the scientific papers, books, and the podcast episode. Primary Source Material Huberman, A. (Host). (2025, December 15). Improve Energy & Longevity by Optimizing Mitochondria with Dr. Martin Picard [Audio/Video podcast]. Huberman Lab. Link to Episode Picard Lab. Mitochondrial Psychobiology Group. Columbia University Irving Medical Center. Link to Lab Website Key Scientific Literature & Books Hood, D. A., Memme, J. M., Oliveira, A. N., & Triolo, M. (2019). Exercise and Mitochondrial Biogenesis. Physiological Reviews, 99(1), 669–715. Read Study Lane, N. (2015). The Vital Question: Energy, Evolution, and the Origins of Complex Life. W.W. Norton & Company. Book Link López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013). The Hallmarks of Aging. Cell, 153(6), 1194–1217. Read Study Mattson, M. P., Moehl, K., Ghena, N., Schmaedick, M., & Cheng, A. (2018). Intermittent Metabolic Switching, Neuroplasticity and Brain Health. Nature Reviews Neuroscience, 19, 63–80. Read Study Picard, M., & McEwen, B. S. (2018). Psychological Stress and Mitochondria: A Systematic Review. Psychosomatic Medicine, 80(2), 126–140. Read Study Picard, M., & Shirihai, O. S. (2022). Mitochondrial Psychobiology: Foundations and Applications. Current Opinion in Behavioral Sciences, 43, 102–110. Read Study Speakman, J. R., & Selman, C. (2011). The Free-Radical Damage Theory: Accumulating Evidence Against a Simple Link. Trends in Ecology & Evolution, 26(1), 33–39. Read Study Wallace, D. C. (2015). Mitochondria and Cancer. Nature Reviews Cancer, 12, 685–698. (Note: Often referenced alongside his Annual Review of Genetics work on aging). Read Study

This episode originally aired as #432 on 5/22/24 and we are bringing it to you again! Parasite cleansing has become a hot topic in the natural health world, but it can feel a little overwhelming. Are you confused about where to start or how to do a cleanse yourself? On this episode of Vitality Radio, Jared demystifies the process by sharing his experience along with his wife's, and a thorough breakdown of the entire process, the products, and what to expect. You'll learn a couple of ways to approach parasite cleansing and which one might be right for you or your family, including kids.  If you never thought about parasites being a problem in America, think again! For a deeper understanding of why parasites are indeed a bigger problem than is understood by most, be sure to listen to Jared's interviews with Dr. Todd Watts and Dr. Jay Davidson - the founders of CellCore.Products:CellCore Para KitVitality Nutrition Parasite CleanseVital 5 Precision Probiotic Vital SporesMagnesium BisglycinateCellCore Bowel MoverLife Seasons Regulari-TRedmond RelyteTrace Minerals Endure Drops***Inquire for capsule-free protocol Additional Information:For information on coaching options and personalized support, please email jessica@vitalitynutrition.comVitality Wellness Community Detox & Support GroupVitality Radio Podcast Listener Community#359: Comprehensive Detoxification of Parasites, Lyme, and Other Toxins With Dr. Todd Watts of CellCore Biosciences#431: Are Parasites Part of Your Health Concerns? With Dr. Jay Davidson#385: Rebalancing and Healing the Body Through Functional Medicine Detoxification With Dr. Stephen Cabral#258: Your Magnesium User's Guide***Be sure to check out all of the Emotional Vitality Episodes, including Jen's Story mentioned in this showVisit the podcast website here: VitalityRadio.comYou can follow @vitalityradio and @vitalitynutritionbountiful on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Please also join us on the Dearly Discarded Podcast with Jared St. Clair.Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

My guest today is Dr. Alexis Cowan, PhD,, a Princeton-trained molecular biologist specializing in metabolism, mitochondrial function, and circadian biology. We talk about why modern science has drifted into scientism, how mitochondrial dysfunction sits at the root of nearly every chronic disease, and why reclaiming sovereignty over your health is both radical and necessary. We dive deep into light biology, circadian rhythms, sun exposure, quantum biology, and the incentives that shape (and distort) modern medicine. We also explore Alexis' personal health journey, her break from academia, her work with Jack Kruse's ideas, and how Bitcoin, self-custody, and proof-of-work thinking mirror biological truth.→ Please like, comment, share & follow — to help me beat the suppressing big tech algorithms & gov. censorship. Thank you!– SPONSORS –→ Get your TREZOR wallet & accessories, with a 5% discount, using my code at checkout (get my discount code from the episode - yep, you'll have to watch it): https://affil.trezor.io/SHUn→ Have you tried mining bitcoin? Stack sats directly to your wallet while saving on taxes with Abundant Mines: https://AbundantMines.com/Efrat - Claim your free month of hosting via this link– AFFILIATES –→ Get 10% off on Augmented NAC to detox Spike protein, with the code YCXKQDK2 via this link: https://store.augmentednac.com/?via=efrat (Note, this is not medical advice and you should consult your MD)→ Be good to your eyes & health, and get the Daylight tablet - a healthier, more human-friendly computer, with zero flicker and zero blue light, by design. Thank me later ;-) https://bit.ly/Efrat_daylight→ Get a second citizenship and a plan B to relocate to another country with Expat Money, leave your details for a follow up: https://expatmoney.com/efrat→ Watch “New Totalitarian Order” conference with Prof. Mattias Desmet & Efrat - code EFRAT for 10% off: https://efenigson.gumroad.com/l/desmet_efrat→ Join me in any of these upcoming events: https://www.efrat.blog/p/upcoming-events– LINKS –Dr. Alexis Cowan's website: dralexisjazmyn.comAlexis' courses (Code HOLYDAYS for 10% off): https://dralexisjazmyn.thinkific.com/collections/products X: https://x.com/dralexisjazmynInstagram: instagram.com/dralexisjazmynYoutube: https://www.youtube.com/@UndoctrinateYourselfEfrat's Twitter: https://twitter.com/efenigsonEfrat's Channels: https://linktr.ee/efenigsonWatch on all platforms: https://linktr.ee/yourethevoiceSupport Efrat's work: ⁠https://bit.ly/zap_efrat– CHAPTERS –00:00 – Coming up.. 01:40 - Intro to Dr. Alexis Cowan05:05 - Why is Alexis dancing? 08:30 - Biology & health in the spiritual, divinity lense10:15 - Why did Alexis chose medical & biology route16:35 – Mitochondria, ATP & how energy actually works26:30 - Why modern science isn't focused on Mitochondria?32:43 – Ad Break – Trezor & Abundant Mines34:49 – How light regulates biology: circadian signaling & daily habits40:37 – Blue light + UV fear: the “block UV at all costs” narrative45:41 – Melanin, skin tone, sunlight, & artificial lights 59:40 - Skin cancer & the sun's benefits1:03:36 – Get a tan to reduce nnEMF / Wireless / 5G radiation!1:07:37 – Mitochondria's health, Transhumanism and nnEMF damages  1:19:09 – Ad Break – Expat Money & New Totalitarian Order (Mattias Desmet)1:20:55 - Grounding benefits1:24:49 – Where should we live geographically?1:29:00 – Overcast & geoengineered skies impact on light therapy 1:34:30 – Adverse reactions & cancer post C jabs1:40:40 - Prepare your body to travel & flights1:44:40 – Tips for trauma, anti-depression and stress1:56:05 - The vision for decentralized science & health 2:04:30 – The education system problems & Alexis' suggestions2:08:30 - Bitcoiners, incentives & sovereignty

In this episode, Dr. Jockers explores with Jason Prall how mitochondrial health and the gut microbiome are deeply connected, shaping energy, inflammation, and long-term resilience. You'll learn why mitochondria are far more than energy producers and how their communication drives whole-body health.   In this episode, you'll discover how the microbiome helps translate food into signals that influence mitochondrial function, metabolism, and cellular repair. Jason breaks down why diversity in the gut matters and how everyday choices quietly shape this internal dialogue.   In this episode, you'll hear practical insights on how sleep, light exposure, movement, fasting, and stress act as signals that either strengthen or weaken this mitochondrial–microbiome connection. The conversation leaves space to rethink how small lifestyle shifts can create powerful biological change.     In This Episode:  00:00 Introduction to Human and Mitochondrial DNA 04:06 Deep Dive into Mitochondria and Aging 14:01 Understanding the Gut Microbiome 25:38 Environmental Factors Affecting Health 29:19 Mindfulness and Detoxification 29:55 Impact of Thoughts on Health 31:06 Personalized Health Approaches 31:39 Universal Health Strategies 33:43 Importance of Sleep 37:19 Exercise and Movement 41:07 Fasting and Meal Timing 45:48 Stress and Recovery Balance 48:42 Final Thoughts and Resources     If you want practical, natural strategies to balance your hormones, heal your gut, boost your energy, and slow aging, don't miss The Dr. Josh Axe Show. Dr. Axe blends ancient wisdom with cutting-edge science and brings on world-class experts for unfiltered conversations you won't hear anywhere else. Transform your health from the inside out and subscribe to The Dr. Josh Axe Show, with new episodes every Monday and Thursday.   Support glowing skin, stronger joints, better digestion, and deeper sleep with Paleovalley's 100% Grass-Fed Bone Broth Protein. Unlike most brands that use hides and skins, Paleovalley slow-simmers real beef bones to extract collagen, glycine, and key amino acids that boost metabolism and reduce inflammation. Each scoop delivers 15 grams of collagen and the clinical dose of glycine for better sleep. Get 15% off at paleovalley.com/jockers.     "Every disease involves mitochondria—when mitochondrial function fails, the body breaks down."      Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio     Resources: Paleovalley Bone Broth Protein: Save 15% on grass-fed bone broth protein at paleovalley.com/jockers.   Connect with Jason Prall: Book:  https://amzn.to/3YC78Wt Website:  humanlongevityfilm.com, beyondlongevitybook.com   Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/ 

What if the anxiety, burnout, inflammation, or exhaustion you carry didn't begin with you?In this solo episode, Dr. Taz explores the emerging science behind generational trauma and how stress, fear, and survival patterns can be passed down biologically through mitochondrial DNA, the nervous system, and hormonal pathways. She explains why some people struggle with symptoms that don't resolve despite doing everything right, and how ancestral trauma may be quietly shaping inflammation, cortisol levels, emotional regulation, and energy production across generations.You will learn how trauma can alter mitochondrial function, disrupt the HPA axis, and create inherited patterns of hypervigilance, anxiety, burnout, and chronic disease. Dr. Taz introduces her five body map framework, physical, mental, emotional, spiritual, and community, to help you understand where inherited trauma may be showing up and how healing becomes possible when all layers are addressed.Dr. Taz shares: • How trauma can be transmitted biologically through mitochondrial DNA passed down the maternal line • Why chronic inflammation, insulin resistance, and cortisol dysregulation often appear in families with histories of displacement, silence, or survival stress • The signs of inherited nervous system patterns, including hypervigilance, fear based thinking, emotional suppression, and burnout that starts early • How ancestral trauma affects hormones, energy production, mental health, and emotional regulation • Why family secrets, shame, and silence can destabilize the entire family ecosystem and show up as disease • The five body map approach to screening generational trauma across physical, mental, emotional, spiritual, and community layers • Practical ways to begin healing, including nervous system regulation, storytelling, somatic release, mitochondrial support, and restoring safe connection within familiesWhether you are dealing with unexplained symptoms, chronic stress, emotional patterns that seem bigger than your life experience, or simply want to understand your family's health history more deeply, this episode offers a new lens on healing. You may inherit biology, but you can change how it is expressed and what gets passed forward.Stay Connected:Connect further to Hol+ at https://holplus.co/- Don't forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Follow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsGet your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseHost & Production TeamHost: Dr. Taz; Produced by ClipGrowth.com (Producer: Pat Gostek) (00:00) - Hi everyone, it's Dr. Taz. Before we get into today's episode, I just wanna pause and say thank you. Your messages, your shares, your stories are, the reason we make Whole Plus every conversation here is about connecting the science, the intuition, and everyday life together so you can feel more like yourself. (00:00) - if you haven't already hit that subscribe or follow button, it helps us reach more people who need this. All right, let's begin. What if the pain you [00:00:30] carry didn't start with you? Science now shows that trauma can be passed through generations, not just through stories or behaviors, but through biological changes in the body itself. (00:00) - this episode, we're exploring the connection between ancestral trauma and mitochondrial DNA and how your body might still be echoing the stress, the fear, or the survival patterns of your lineage. The gift of being in practice for over 16 years and seeing, I don't know how [00:01:00] many patients, I think collectively as, uh, a series of whole plus clinics were at 60, 70,000. (00:00) - the gift of seeing a patient day in and day out and following them through their journey. Allows us as providers a lot of time to think, observe, learn, and listen. And one of the things that has always confused me until recently is why some people have symptoms or have issues without any explanation.[00:01:30] (00:00) - done all the right things. They're following the diet, they're exercising, they are doing all the things they're supposed to do. They've got those wellness routines down, red, light, blue, light, you name it, they're doing it, but they're still not well. And while I could have a conversation with all of you about chemistry and biology and physiology, here's what maturity and time has taught me. (00:00) - healing and being well doesn't exist on [00:02:00] one plane. It's not just about the numbers and the data. It's actually a whole lot more, so much more that it may even be linked to your generational trauma. Now, bear with me for a second. Please don't roll your eyes and change the channel or flip the screen. (00:00) - is important information and we are just beginning to understand what all of this means and how it's all connected. I've had many opportunities to observe [00:02:30] this. Some of them begin right in our home. I have watched as the women in our family have a very similar look in their eye demeanor way of talking tone. (00:00) - name it. Some of it we could explain away. My mom was an immigrant, came here at a very young age, 17, 18, 19 years old, had an arranged marriage. She had, I thought, the insecurity of being an immigrant, of being somebody in a new [00:03:00] country without a community. And I always explained away her inability or fear. (00:00) - of in terms of taking action or taking next steps as a part of that story, the immigrant story, right? I, I can't imagine what so many immigrants go through to get here and then to build a life in a family of their own, leaving behind mothers and fathers, brothers and sisters, huge families. So I explained her story away that way. (00:00) - then there [00:03:30] was me and I grew up, as I've shared sometimes in a slightly chaotic, dysfunctional childhood home, and I don't wanna get into all of those details, but I had that same glimmer of fear and insecurity that I saw in my mom. But let's fast forward to my daughter all these years later, growing up in a pampered home with a father that dotes on her. (00:00) - we doted on her even a bit too much, but regardless, had all the comforts and the [00:04:00] security that anybody externally could provide. But guess what? The same glimmer, that same sparkle, that same sort of tone. Something, I can't describe it, where there's fear...

In this episode, Coach Debbie Potts sits down with Dr. Zulia Frost, Co-Founder and Medical Director of Recharge Health, to explore how targeted red light therapy can support mitochondrial repair, thyroid function, gut health, liver detoxification, and overall metabolic resilience for adults navigating midlife. If you are in your 40s, 50s, 60s, or beyond and want to improve your energy, metabolism, hormone balance, digestion, and recovery, this conversation provides the education, tools, and strategies you need to optimize your health from the inside out. Zulia explains the science behind photobiomodulation, how red and near-infrared light activate cellular energy pathways, and why FlexBeam delivers medical-grade targeted therapy directly to organs and tissues that need it most. We break down the research on mitochondrial function, Hashimoto's and thyroid hormone conversion, gut inflammation, motility challenges, liver congestion, stress recovery, and active aging. This episode is especially relevant for midlife athletes, high performers, over-40 adults experiencing metabolic slowdown, and anyone wanting to age with strength, clarity, and vitality. Mentioned in the Episode FlexBeam by Recharge Health Try FlexBeam and save with code: CoachDebbiePotts Website: https://recharge.health (affiliate support is appreciated) Topics Covered • Why mitochondrial function declines with age and how red light supports ATP production • The connection between photobiomodulation and thyroid hormone activation • Clinical research on PBM for Hashimoto's and autoimmune thyroid dysfunction • Red light therapy for gut inflammation, motility, and microbiome balance • Liver detoxification, metabolic health, and targeted PBM application • Supporting the nervous system, vagal tone, sleep quality, and stress recovery • FlexBeam protocols for midlife athletes and active aging • How to integrate daily PBM routines into lifestyle, training, and recovery • Why targeted photobiomodulation works differently from full-body light panels About Zulia Frost Dr. Zulia Frost is a pioneer in photobiomodulation, neuromuscular rehabilitation, and integrative medicine. With more than two decades of clinical experience, she is internationally recognized for her work in cellular repair technologies and her scientific leadership at Recharge Health. Connect with Coach Debbie Potts Website: https://www.debbiepotts.net Podcast: The Coach Debbie Potts Show YouTube: https://www.youtube.com/@coachdebbiepotts Instagram: @coachdebbiepotts Email: coachdebbiepotts@icloud.com Support the Show If this episode helped you understand how to age stronger instead of slower, please rate, review, and share it with someone looking to improve their health, metabolism, and longevity.

What if the root cause of our most devastating chronic diseases—from Alzheimer's and cardiovascular disease to diabetes and cancer—could be traced back to the same cellular structures? And what if these tiny organelles hold the key to understanding how we age and potentially extending our healthspan?Dr. Hemal Patel, Professor in the Department of Anesthesiology at UC San Diego School of Medicine, takes us on a fascinating journey into the world of mitochondria. Far from being mere "powerhouses of the cell" as we learned in school, these ancient bacterial descendants play sophisticated roles as gatekeepers of cellular life and death, potential drivers of cell differentiation, and central players in understanding chronic disease.When functioning properly, mitochondria form interconnected communities within our cells—appearing like strings of pearls in heart cells, which devote a remarkable 30% of their volume to these energy-generating structures. But when these connections break down, disease follows. Dr. Patel explains how every chronic condition can be viewed through the lens of energy imbalance, with mitochondria at the center of this critical equation.Perhaps most exciting is the breakthrough technology Dr. Patel's team has developed: a simple blood test called MeScreen that can assess mitochondrial function without invasive biopsies. Using just a few drops of blood, this revolutionary approach reveals each person's unique mitochondrial signature, offering personalized insights that could transform how we approach health optimization and disease prevention.Whether you're curious about the fundamental biology of life, seeking to understand chronic disease, or interested in cutting-edge approaches to longevity, this conversation will forever change how you think about the trillions of tiny organelles powering every aspect of your existence. Discover why supporting these ancient symbionts might be the missing link in our pursuit of longer, healthier lives.https://mescreen.com/cart/47561239626013:1?discount=&ref=emssndtq (Use the code MITOHEALTH100 for $100 off)Lies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (LUFKIN20 for 20% off) https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin At home blood testing (20% off) https://siphoxhealth.com/lufkin Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmdInstagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: https://www.facebook.com/robertlufkinmd Bluesky: ...

Popular media leverage weak study to criticize RFK Jr.'s rethink of standard recommendations for saturated fat avoidance; Poor quality plant-based diets hike cardio risk; A listener complains his lp(a) is going up with age despite his healthy diet, lifestyle; Scientists pinpoint cocoa ingredient that slows aging; Berry proanthocyanidins preserve brain power; Tattooing may promote inflammation, undermine immunity.

Country singer Jellyroll dishes on his triple-digit weight loss odyssey; DGL for GERD—will it raise blood pressure? CBD curbs aggression in dogs; Hundreds of environmental chemicals may imbalance our microbiomes; ADHD isn't just a malady—it may impart unrecognized superpowers; The evolutionary mismatch between our ancient genes and modern artificial environments; Could napping improve cognitive function? Heart attacks, lung problems soared after LA wildfires; HHS Secretary RFK Jr. focuses attention on inadequate testing, treatments for chronic Lyme Disease.

In this episode, Coach Debbie reveals why your thyroid isn't the problem — your cellular environment is. Learn how vagus nerve dysfunction, LPS, H. pylori, low stomach acid, sluggish bile, and mitochondrial stress block T4 → T3 conversion and prevent T3 (even medication!) from entering your cells. Debbie shares her personal case study connecting GI-MAP, MEScreen mitochondrial testing, blood chemistry, HRV, and vagus nerve suppression to low T3 activation, slow metabolism, and performance plateaus. Key topics: • Why T3 meds don't always work • How LPS blocks thyroid hormone • Gut–vagus–thyroid connection • Bile flow + fat-burning • Mitochondria + metabolism • How stress shuts down thyroid activation Pulsetto Vagus Nerve Stimulation:

In this episode of the Let's Talk Thyroid podcast, I am speaking with Dr. Sam Shay, a functional medicine expert, discussing the complexities of thyroid health. We explore the importance of comprehensive thyroid testing - not just the thyroid panel but other tests that can help unpack solutions to managing thyroid health. Dr Shay identifies 6 often overlooked categories of tests to explore:Nutritional deficienciesMitochondriaGut HealthGeneticsHormonesAdrenalHere is some of what we talk about and where to find it00:00 Introduction to Functional Medicine and Thyroid Health05:29 Understanding Thyroid Testing and Nutritional Deficiencies11:00 The Role of Mitochondria in Thyroid Function17:01 Gut Health and Its Impact on Thyroid22:40 Genetics and Thyroid Health28:10 The Influence of Hormones and Stress on Thyroid Function33:42 Holistic Approaches to Thyroid ManagementDr. Sam Shay, DC, IFMCP is a functional medicine expert, speaker, and stand-up comic who helps people get out of survival mode and reclaim their energy, focus, and vitality through personalizedfunctional lab testing and his signature NeuroHarmony Model™After overcoming years of chronic fatigue, insomnia,and digestive issues since childhood, Dr. Sam turned his recovery into a mission. He's spent the last 25 years mastering the science of nutrition, mind-body medicine, and clinical lab testing to decode the root causes of burnout, overwhelm, and chronic health issues.Known as the “friendly lab nerd,” Dr. Sam makes advanced lab testing approachable—combining deep data analysis with relatable insights to help clients balance hormones, heal the gut, optimizesleep, and reduce inflammation. His unique NeuroHarmony Model™ weaves together functionaltesting with nervous system regulation to create sustainable health—not just short-term symptomfixes.He's been featured on over 200 podcasts and summits and brings an engaging, humorous tone to even the most complex health topics. Dr. Sam empowers his audience with practical tools to feelbetter and function at their best.Connect with Dr Shay:YouTube: https://www.youtube.com/tenpointwellness/Facebook: https://www.facebook.com/sam.shay.792/Instagram: https://www.instagram.com/drsamshay/Head to drsamshay.com/DNA-decoded and enter code GOLD100 for $100 off the Gold programLet's Talk Thyroid is a podcast where we explore different aspects of living thyroid-friendly lifestyle positively & practically to help you thrive and not just survive.⭐️  WEBSITE: https://letstalkthyroid.com

What if you're looking for healing in all the wrong places?After two years of guiding clients through integrative cancer care, Dr. Katie reflects on the most important lessons that completely transformed her practice. She shares why the natural healing space feels so overwhelming and confusing, even for someone with decades of medical training. If you've ever felt paralyzed by conflicting advice or stuck choosing between conventional and natural approaches, you'll understand why this clarity matters.Dr. Katie opens up about a major pivot in her work and reveals how mitophagy and mitochondrial repair may help explain why people emerge from extended fasting as completely different versions of themselvesAccess the FREE Water Fasting Masterclass Now: https://www.katiedeming.com/the-healing-power-of-fasting/Chapters:06:30 - Give Yourself Permission to Pivot07:31 - Fear Is the Real Fog09:30 - Illness as a Wake Up Signal13:30 - Stop Consuming Content Like Medicine17:20 - Natural vs Conventional Is a False War20:00 - The Emotional Patterns That Keep People Sick25:30 - Mitochondria: The Missing Link in Chronic Illness32:00 - Water Fasting as a System Reboot37:53 - The Five Lessons That Changed Her PracticeShe explains why she increasingly believes most illness might actually be rooted in something many practitioners miss, and shares the one practice that addresses physical healing, emotional release, and spiritual alignment all at once. You'll discover why healthy mitochondria may be a missing piece in many healing journeys.She challenges common assumptions about what creates lasting health changes. Whether you're managing a diagnosis, supporting someone who is, or simply seeking optimal wellness, Dr. Katie's insights about emotional patterns, cellular health, and the courage to pivot when something isn't working will shift how you approach your own path forward.LisAccess the FREE Water Fasting Masterclass Now: https://www.katiedeming.com/the-healing-power-of-fasting/ Transform your hydration with the system that delivers filtered, mineralized, and structured water all in one. Spring Aqua System: https://springaqua.info/drkatieMORE FROM KATIE DEMING M.D. Work with Dr. Katie: www.katiedeming.com 6 Pillars of Healing Cancer Workshop Series - Click Here to Enroll Follow Dr. Katie Deming on Instagram: https://www.instagram.com/katiedemingmd/ Email: INFO@KATIEDEMING.COM Please Support the Show Share this episode with a friend or family member Give a Review on Spotify Give a Review on Apple Podcast Watch on Youtube: https://youtube.com/playlist?list=PL5LplU70TE9i01tW_7Tozi8b6X6rGBKA2&si=ZXLy5PjM7daD6AV5 DISCLAIMER: The Born to Heal Podcast is intended for informational purposes only and is not a substitute for seeking professional medical advice, diagnosis, or treatment. Individual medical histories are unique; therefore, this episode should not be used to diagnose, treat, cure, or prevent any disease without consulting your healthcare provider.

Dr. Martin Picard, PhD, is a professor of behavioral medicine at Columbia University and an expert on how our behaviors and psychology shape cellular energy production and rates of aging. He explains that your mitochondria don't just “make energy”; they translate what you do—your mindset and your relationships—into the energy you experience as vitality or lack thereof. He explains how exercise, nutrition, sleep, meditation, and even certain thought patterns and our sense of purpose can charge our cells like batteries. He also shares findings that hair greying is the result of cellular stress and is reversible. This episode links physical and mental ‘energy' with cellular energy and provides science-supported tools to improve your physical and mental health. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Helix: https://helixsleep.com/huberman Lingo: https://hellolingo.com/huberman Function: https://functionhealth.com/huberman Waking Up: https://wakingup.com/huberman Timestamps (00:00:00) Martin Picard (00:03:50) What is Energy?, Energy Flow & Transformation (00:07:53) Energy, Vitality, Emotions, Sensory Perception (00:14:18) Sponsors: Helix Sleep & Lingo (00:17:19) “Mito-Centric” View of World, Mitochondrial Energy & Information Patterns (00:25:26) Organelles, Mitochondria & Energy Transformation; Maternal Genes (00:31:12) Mitotypes & Differentiation, Mitochondria as “Social Organisms” (00:36:52) Food & Dysfunctional Energy Transformation (00:40:02) Lifestyle Choices & Interests, Physiological Growth (00:46:39) Pregnancy, Amenorrhea; Illness & Tiredness (00:51:07) Sponsor: AG1 (00:52:29) Energy Transformation & Distribution; Body's Wisdom, Feeling Sick (00:56:27) Tool: Feel Your Energy; Breath & Energy (01:02:31) Flow of Energy; Trade-Offs, Life Purpose & Enjoyment (01:10:15) Biology, Meaningful Experiences & Energy Flow (01:16:27) Sponsor: Function (00:18:15) Inflammation, Energetic Flow (01:20:43) Child Prodigies, Species Lifespan & Mitochondrial Metabolism; Aging (01:28:56) Lifestyle & Aging: Exercise, Fasting; Inflammation, Sleep, Stimulants (01:37:06) Energetic Stress Signals, GDF-15, Cancer, Heart Failure (01:42:18) Genes, Lifestyle & Aging (01:47:54) Gray Hair Reversal, Stress; Inflammation & Aging (01:57:37) Energy Recovery, Sleep & Mitochondrial Function, Stress, Meditation (02:05:16) Tools: Yoga Nidra, NSDR; Pre-Sleep Relaxation, Energy & Restorative Sleep (02:10:58) Diet & Individualization, Clinical Trials; Mitochondria & Nutrition, Keto (02:20:14) Alcohol & Energy Budget; Stress (02:25:02) Exercise, Increase Mitochondria, Overtraining; Resistance & Growth (02:33:06) Sponsor: Waking Up (02:34:41) Supplements & Mitochondria Health, Deficiencies, SS31, Methylene Blue (02:41:31) Energy Flow & Experiences, Balance (02:49:13) Transform Through Resistance, Energetic Awareness, Connection (02:56:05) Food Overconsumption & Mitochondria Disruption; Tissues & Mitochondria (03:01:02) Mitochondrial Health Test; Tool: Ways to Increase Energy; Meditation (03:06:10) Peptides; Fertility Supplements, Urolithin A; Electromagnetic Fields (03:12:16) Acknowledgements (03:14:15) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices

The pros and cons of natural vs synthetic vitamins; Telehealth site for ADD meds lands founder in prison; Why eradicating H. pylori may set the stage for Alzheimer's; Why integrative physicians often don't accept insurance; Far-infrared phototherapy may offer “electroceutical” treatment for dementia; Hobbies may forestall all-cause mortality—by 29%! 

This week I interviewed Dr. Kevin Smith.  Dr. Smith is a functional medicine practitioner and founder of the Chronic Conditions Center in Pittsburgh, PA. He specializes in helping people understand and fix the root causes of chronic health problems—including gut issues, autoimmunity, chronic pain, thyroid dysfunction, adrenal fatigue, and inflammation—using natural, non-invasive methods. We discussed proper sleep hygiene along with:- testing for thyroid issues- how Dr. Smith solves individuals' health issuesand his one tip to get your body back to what it once was!Connect with Dr. Kevin Smith:  https://www.chronicpa.com/-------How to Take Simple Steps to Reclaim the Body, Energy, and Strength You Had 10-15 Years Ago Using My Stepladder System:https://www.stepladdersystem.com/FREE Nutrition Cheatsheets:https://brian-getleaneatclean.beehiiv.com/subscribeClick to book a FREE 15 minute consult with Brian:https://calendly.com/bdgryn/15min------------Interested in Upgrading your Mitochondria, Improving Energy and Sleep! Check out Troscriptions: https://bit.ly/4ik5kK5Use Discount Code for 10% OFF: EATCLEAN----Watch Get Lean Eat Clean podcast video episodes on YouTube!YouTube.com/@briangryn3680----B.rad Whey Protein Isolate Superfuel:The Best Protein on The Planet! Available in Two Delicious Flavors: Vanilla Bean and Cocoa BeanUse Coupon Code glec10off for 10% off your order!https://a.co/d/731gssV----My favorite health bars with clean ingredients!https://www.eatprima.com/BRIAN6816310% OFF with this link!

Watch the FULL podcast here: https://youtu.be/7kfykswH6IoWhy is zone two training so important for mitochondrial health? It's linked with improvements in fat oxidation and lactate clearance, which are used as surrogates of mitochondrial function in sports science.This clip explores how different exercise intensities drive distinct metabolic responses, why athletes are useful models for understanding cellular energy, and how laboratory testing with metabolic carts and lactate measurements led to practical training zones from easy efforts to sprints. I'm exploring with my guest how zone two work consistently improved fat oxidation and lactate clearance in testing, while higher intensities remain essential for performance and VO2, since competitions are decided at the top end. Here, I'm discussing the balance between building a metabolically efficient engine at the mitochondrial level with zone two, and training the “turbo” at zones four and five plus sprint work for race demands, all in clear, everyday language you can apply.As a nutritionist and health communicator, my aim is to translate these lab insights into practical training decisions that respect both mitochondrial function and cardiorespiratory adaptations.***This episode is sponsored by: NOWATCH: Health tracking reimaginedKnow your body, trust yourself.15% off with code LWBW15 at nowatch.com***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. https://sarahmacklin.substack.com/***Let's be friends!

In this episode of Creating Your Ageless Future, Regan Archibald delivers a powerful deep dive into the science of body composition, metabolic aging, and the peptides reshaping modern regenerative medicine. He breaks down the “Ageless Axis”—the brain, muscle, and heart—and explains how blood sugar, inflammation, mitochondrial function, and visceral fat determine how quickly we age. Regan shares emerging breakthroughs in GLP-1s, Tesamorelin, CJC-1295, AOD9604, and the “Wolverine stack” (BPC-157 + TB500), and reveals how peptides act as metabolic reset systems rather than dependency-forming drugs. Along the way, he celebrates real client transformations, exposes misconceptions about weight loss drugs, explains why muscle is the antidote to gravity, and updates listeners on new Ageless Future pharmacy innovations. This episode is part science class, part biohacking blueprint—everything you need to build a younger, stronger, more resilient future. AGELESS FUTURE:Book Comprehensive Labs: https://agelessfuture.com/longevity-labs/FREE copy of The Peptide Blueprint: https://agelessfuture.com/blueprintSign up for future Health Accelerator Challenges calls LIVE! https://us02web.zoom.us/webinar/register/WN_YZsiUMOzSyqcE8IinC5YEQ#/registrationBooks: https://www.amazon.com/Books-Regan-Archibald/s?rh=n%3A283155%2Cp_27%3ARegan%2BArchibaldArticles: https://medium.com/search?q=Regan+ArchibaldLIKE/FOLLOW/SUBSCRIBE AGELESS FUTURE:YouTube -https://www.youtube.com/@ReganArchibald / https://www.youtube.com/@Ageless.FutureLinkedIn: https://www.linkedin.com/in/regan-archibald-ab70b813Instagram: https://www.instagram.com/ageless.future/Facebook: https://www.facebook.com/AgelessFutureHealth/DISCLAIMER: Here's the info scoop: everything on this channel is purely for educational and informational kicks—definitely not medical advice. We're here to share the good stuff on wellness and longevity, but let's be clear: the FDA hasn't signed off on any of it. Our aim? To inspire and inform, not play doctor. So before diving headfirst into any health crusade, check in with your healthcare pro. Absorb, explore, and stay curious! 

Revolutionary study highlights anti-aging benefits of collagen supplementation; Creatine gummies flunk potency tests; Do small irregularities on an endoscopy dictate a lifetime prescription for acid-blockers? How exercise slows cancer and forestalls dementia; Pregnant women require frequent thyroid checks to avert autism; Fructose may stoke body-wide inflammation; What causes bleeding gums? 

If you're over 40 and have been told your ovarian reserve is low, you've likely heard things like your only option is IVF with donor eggs or your time has run out. But those statements rarely tell the full story. In today's episode, Improve Ovarian Reserve to Get Pregnant After 40, we explore what ovarian reserve actually measures, why it does not define your fertility potential, and how a functional fertility approach can support egg quality, hormone communication, and your chances of pregnancy, whether naturally or with IVF. Even after 40, your body can respond when you understand the underlying imbalances that influence ovarian function. You'll learn • What AMH, FSH, and AFC truly indicate and why they don't measure egg quality • How mitochondrial energy, nutrient levels, and antioxidants influence egg development after 40 • The role of thyroid health and why optimal TSH should be below 2.0 when trying to conceive • How gut infections, immune dysregulation, and vaginal microbiome imbalances affect ovarian reserve • Which functional tests help uncover hidden imbalances that impact egg potential, including GI MAP, DUTCH, GrowBaby, and HTMA This episode is especially for you if: • You are 40 or older and have been told your AMH is low or your FSH is high • You have experienced failed IVF cycles, early loss, or poor egg quality and want to know what else you can do • You want a functional fertility framework that looks at hormone communication, egg energy, and whole body imbalances rather than just chasing lab numbers Next Steps in Your Fertility Journey Subscribe to Get Pregnant Naturally for evidence-based guidance on functional fertility, and share this episode with anyone on their fertility journey. Not sure where to start? Download our most popular guide:  Ultimate Guide to Getting Pregnant This Year If You Have Low AMH/High FSH it breaks everything down step by step to help you understand your options and take action For personalized support to improve pregnancy success, book a call here. --- Timestamps 00:00 What low ovarian reserve really means after 40 Why AMH and FSH do not predict your ability to conceive and why your fertility is not defined by these numbers. 01:00 AMH, FSH and AFC explained for women over 40 How ovarian reserve tests measure quantity, not quality and why functional fertility looks deeper. 02:00 Case study: Diminished ovarian reserve at 41 with autoimmune clues A real example of low AMH and Hashimoto's with gut infections that resulted in a natural pregnancy. 04:00 Mitochondria and egg energy after 40 How mitochondrial function influences egg maturation and which nutrients support better ovarian energy. 05:00 Thyroid health and why TSH must be optimal to conceive The full thyroid picture and why ferritin, antibodies and gluten sensitivity matter for ovarian reserve. 07:00 Mineral balance and heavy metals that affect ovarian reserve How magnesium, copper imbalance and toxic metals influence egg quality and hormone stability. 08:30 Adrenal stress and cortisol patterns that lower ovarian signaling How chronic stress suppresses FSH and LH and what adrenal patterns look like on testing. 10:00 Gut health, estrogen metabolism and inflammation How dysbiosis, leaky gut and yeast overgrowth interfere with follicle growth and hormone balance. 11:00 Vaginal microbiome and hidden infections linked to failed implantation Why Ureaplasma, Mycoplasma and high pH environments reduce embryo success and implantation. 13:00 Case study: Natural pregnancy at 43 with DOR A woman with low AMH and high FSH who addressed gut, adrenal and thyroid imbalances and conceived naturally. --- Resources

In this GSD Mode Health & Fitness Podcast we discuss the Peptide Mots-C and it's impacts on Mitochondria, Energy Levels and more.   Check Out ZONE (Amazing Nootropic for Mental Focus and Energy): https://forjlife.com/products/zone-nootropic-supplement-mental-focus-eye-fatigue   *Disclamer: This is NOT medical advice. Please make sure to seek your own medical professional for your medical advice. 

Today, I'm joined by the incomparable Dr. Ted Achacoso—a true pioneer in shifting healthcare from "what's wrong with you" to "what's right with you." Trained across neurology, pharmacology, AI, and nutritional medicine, Dr. Achacoso brings a sharp mix of science, humor, and unfiltered honesty to our conversation. We get real about what it takes to optimize health at the cellular level, why metabolomics is the future doctors can't ignore, and how something as simple as a toxicity panel can completely change your health trajectory.   Episode Timestamps: Welcome and episode introduction ... 00:00:00 Science, laughter, and Dr. Ted's background ... 00:00:38 Early curiosity, accelerated medical pathway ... 00:07:20 Reframing healthcare: from disease to wellness ... 00:14:04 Cell danger response and importance of metabolomics ...00:16:15 Case study: toxicity panel as diagnostic game-changer ... 00:35:17 Patient motivation and behavioral change ... 00:44:20 Vitamin D: its underestimated power and role ... 00:51:12 Vitamin D paradox, genetics, and medication effects ... 01:00:34 Daily longevity habits and mindset ... 01:22:03 Longevity in one word: balance ... 01:33:05 Home Hope resources and closing ... 01:35:20   Our Amazing Sponsors:   Tro Mune by Troscriptions - Cold season doesn't have to take you out. I use Tro Mune—a nightly buccal troche with 75 mg cordycepin—to build immune resilience while I sleep. Take ½–1 before bed, and use it before you get sick or right when you feel it. Troscriptions.com, use NAT10, and get 10% off your first order.   Digestive Bitters by Just Thrive - One capsule before eating helps your body absorb more nutrients, ease digestion, and leave you feeling light instead of weighed down. Head over to Justthrivehealth.com/discount/NAT and use code NAT20 for 20% off.   Tranq Dart by Wizard Sciences - a multi-pathway sleep support from Wizard Sciences. It's not a knockout pill; it's a gentle nudge toward that wind-down zone. I take it about 30 minutes before bed, and it helps my body and brain sync up for sleep. Visit wizardsciences.com and use code NAT15 for 15% off. Sleep smarter, not harder.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

In this episode of Everything Is Personal, Len sits down with Chris Bur – co-founder of the oldest ESS60 manufacturer and author of Live Longer and Better. They break down the story of C60 vs ESS60, how a “Nobel-linked” discovery turned into MyVitalC, and what the science really says about longevity, healthspan and mitochondria. EndoDNA: Where Genetic Science Meets Actionable Patient CareEndoDNA bridges the gap between complex genomics and patient wellness. Our patented DNA analysis platforms and AI technology provide genetic insights that support and enhance your clinical expertise.Click here to check out to take control over your Personal Health & Wellness Connect with EndoDNA on SOCIAL: IG | X | YOUTUBE | FBConnect with host, Len May, on IG Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The most common complaints Dr. Friedman hears from patients are a lack of energy and brain fog. Many people turn to these quick fixes like caffeine, sugar, stimulants, and energy drinks. But unfortunately, these things can wreak havoc on our hormones and lead to an array of unhealthy conditions.  Joining us today is returning guest and friend Ari Whitten with his new book "Eat for Energy." He shares the secrets to restoring energy, cognitive function, and alertness!Ari Whitten is a number one bestselling author of several cutting-edge books and holds two advanced certifications from the National Academy of Sports Medicine and a Ph.D. in clinical psychology. He's the host of the popular energy blueprint podcast, which brings together the world's leading experts on the subject of fatigue and energy enhancement.Listen as Ari & Dr. Friedman discuss a range of topics in this XL episode, including mitochondria, coffee and getting good sleep, and choosing the best diet plan.To learn more or get your copy of Eat for Energy go to: https://theenergyblueprint.com/eat-for-energy-book/

How does mitochondrial function directly influence aging in the skin and what can we do to support it? Why do our energy levels affect the way we show up in life, from social interactions to self-care? In this episode, Dr. Dan Pardi and I explore one of the most powerful foundations of youthful, radiant skin: mitochondrial health. We dive into how vitality, energy production, and cellular function directly influence not only how we age, but how we feel, and how we show up in our daily lives.Shop Qualia: http://www.qualialife.com/rachelYou're going to love this conversation, and you're going to want to share it with everyone you care about who also desires to look and feel their best too!Learn more about Dr. Dan Pardi:Dr. Dan Pardi is the Chief Health Officer at Qualia Life Sciences, where he leads education to advance healthspan and peak performance. He's the founder of humanOS.me and host of humanOS Radio, the official podcast of the Sleep Research Society. Dan has advised elite military units, Fortune 500 companies, and startups through his consultancy, Vivendi Health. He holds a PhD in Cognitive Neuroscience from Leiden University and Stanford, and speaks regularly at events like TEDx, VC Firms, and the Institute for Human Machine Cognition.Connect with Dan:Facebook: @QualiaLifeInstagram @qualialifeLinkedIn: https://www.linkedin.com/in/danpardi/Step into your Radiance Sanctuary in the Membership https://www.theschoolofradiance.com/membershipFor more resources related to today's episode, click here for the podcast episode page: https://www.theschoolofradiance.com/podcasts Follow Rachel Varga Official on Instagram: https://www.instagram.com/rachelvargaofficial/ —Catch full episodes of The School of Radiance Podcast here on YouTube https://www.youtube.com/@RachelVargaOfficial —Subscribe to the YouTube channel here: https://www.youtube.com/@RachelVargaOfficial —Follow me here:Instagram: https://www.instagram.com/rachelvargaofficial/ Facebook: https://www.instagram.com/rachelvargaofficial/ Website: https://www.theschoolofradiance.com —FREE STUFF: Download my FREE Skincare Checklist, sign up for my FREE 30 minute biohack your way to clear skin and slowing aging training now, and my newsletter for promos and exclusive events just for you! https://www.theschoolofradiance.com/freebiesEveryone gets one FREE call! Book your free 15-minute call with Rachel Varga to see which options will help you achieve your skin radiance goals! https://rachelvarga.as.me/YourPersonalizedRadianceConsultation —Looking for Skincare products, Tutorials, booking YOUR private One-on-One, and the deep dive Radiance Membership?SHOP skincare: https://alwaysradiantskinshop.comBOOK your private One-on-One: https://rachelvarga.as.me/Initialconsultation REGISTER for Tutorials and/or Membership: https://theschoolofradiance.com As a disclaimer, please note that the information shared in this podcast and interview is not to be taken as medical advice, and it's always important to consult with your physician before making any lifestyle changes. Rachel disclaims any responsibility for inaccurate credentials of guests or information used that may cause harm.Thank you for tuning in to this episode of The School of Radiance with Rachel Varga (formerly The Rachel Varga Podcast and The Always Radiant Skin Podcast)!Rachel Vargainfo@theschoolofradiance.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Is your body running on broken engines?We often obsess over what we eat, but we rarely think about how our cells process that fuel. If your mitochondria (the engines of your cells) are dysfunctional, it doesn't matter how perfect your diet is—you will feel tired, you will recover slowly, and you will age faster.In this episode, we sit down with Brad Currier, a PhD in muscle physiology and scientist at Timeline, to discuss Urolithin A—the breakthrough molecule that acts as a "recycling program" for your cells. Brad reveals why natural food sources are virtually impossible to rely on (you'd need to drink 1.5 liters of juice daily), how this molecule compares to fasting for longevity, and the shocking data coming out of studies with Olympic athletes.In this episode, you will learn:The "Junkyard" Theory: Why mitochondrial dysfunction is the root cause of low energy and poor recovery.Mitophagy Explained: How to trigger the selective breakdown of "zombie" mitochondria to build fresh, healthy ones.The Pomegranate Reality Check: Why you can't eat your way to therapeutic levels of Urolithin A (and the sugar cost of trying).Fasting vs. MitoPure: The difference between "global" starvation (fasting) and "surgical" cellular repair.Olympic Secrets: How elite runners are using this specific protocol to lower perceived exertion and muscle damage.The Future of Longevity: How this impacts not just muscle, but skin, immune health, and cognitive function.Timeline Mitopure Gummies: GET 20% Off Now!

Join us for an eye-opening conversation with Dr. Jess Peatross, a former hospitalist turned integrative and environmental medicine expert. She breaks down the real root causes of chronic illness, from mold exposure and parasites to hidden infections, nervous system dysregulation, toxicity, and mitochondrial burnout.In this episode, Dr. Jess shares her deeply personal journey from conventional medicine to functional healing and reveals the clinical frameworks she now uses to help thousands of patients recover — even the most complex “mystery illness” cases. We cover:•Why conventional medicine misses chronic illness patterns•The shocking truth about mold toxicity and modern home construction•Parasites: symptoms, myths, testing, and treatment•“Kill • Bind • Sweat” explained — and how her protocol has evolved•Why the nervous system is the true starting point of all healing•Mitochondria, detox pathways & drainage essentials•How trauma, stress & freeze states create chronic disease•Histamine intolerance, MCAS, hormones & perimenopause•Best testing approaches for toxins, infections & gut health•Tools clinicians can use to start learning functional and environmental medicine

In Episode 175 of the Fit Mother Project Podcast, Dr. A talks with neuroscientist and MitoQ Chief Science Officer Dr. Siobhan Mitchell about one of the most powerful — and overlooked — drivers of women's health after 40: mitochondrial function. She shares how her grandmother's Alzheimer's diagnosis inspired her career and why the latest science points to mitochondria, oxidative stress, and “inflammaging” as core players in memory, energy, and healthy aging.You'll learn how exercise, smart intervals, fasting, MCT oils, CoQ10, vitamin C, and mitochondrial-targeted antioxidants like MitoQ can help your cells produce cleaner energy, recover faster, and better protect your brain, heart, and muscles. Dr. Mitchell also breaks down what human studies actually show about MitoQ and other mitochondrial supports like PQQ, NAC, and NAD boosters.If you're a busy mom or midlife woman who wants steady energy, clearer thinking, and stronger training results without burning out your system, this conversation will give you a science-backed roadmap.Key TakeawaysMitochondria = powerhouses and “CEOs” of the cellOxidative stress & “inflammaging” drive faster agingBalance matters: not too much, not too little mitochondrial activityExercise (especially intervals) trains mitochondrial resilienceFasting & ketones trigger autophagy and longevity pathwaysMCTs (especially C8/C10) support ketones and brain functionCoQ10 is essential but poorly delivered into mitochondria via standard supplementsMitoQ = mitochondria-targeted CoQ10 derivative with human dataStudies: better power output, recovery, and less exercise-induced DNA damageVitamin C, magnesium, B12 often need supplement support with ageNAC, PQQ, NAD boosters, and urolithin A: promising but mixed dataNo magic bullets: stack smart supplements on top of fundamentalsMore About MitoQ and Dr. Siobhan MitchellWebsite: https://www.mitoq.com/Use code FITFAMILY at checkout for 10% off your purchaseFacebook: https://www.facebook.com/MitoQ/Instagram: https://www.instagram.com/mitoq/YouTube: https://www.youtube.com/user/MitoQHealthX: https://twitter.com/Mito_QTik Tok: https://www.tiktok.com/@mitoqPodcast: Cell Me About It https://open.spotify.com/show/2Bbc0Oi5ypbui2voVpnCxf?si=40f849b961d041ffDr. Siobhan Mitchell's Email: smitchell@mitoq.comBiographical Information on Dr. Siobhan MitchellDr. Siobhan Mitchell, PhD is the chief scientific officer of MitoQ with over 25 years of research experience in how nutrition impacts brain aging, metabolic health, and longevity. She completed her PhD at SUNY Albany and a post-doctoral fellowship on brain aging at University of Washington.Siobhan held roles at the three largest food companies in the world (Unilever, Nestle and Pepsico), leading trials in Europe, North America and Asia, which investigated the effects of nutrition on cognitive decline, mood and performance. Additionally she was senior director at Noom, where she directed a team...

Dr. Glen Jeffery, PhD, is a professor of neuroscience at University College London and a leading expert on how different colors (wavelengths) of light impact cellular, organ and overall health. He explains that long-wavelength light (red, near-infrared and infrared) can enter the body and brain to enhance mitochondrial function and thereby improve metabolism, eyesight, blood glucose regulation, mood, hormones and more. We also discuss how short-wavelength light from LED bulbs can impair mitochondrial health and why balanced, full-spectrum light is essential for health. Dr. Jeffery shares simple yet powerful ways to use natural and artificial light sources to enhance your metabolic function, eyesight and longevity. Sponsors AG1: https://drinkag1.com/huberman Wealthfront*: https://wealthfront.com/huberman Joovv: https://joovv.com/huberman Rorra: https://rorra.com/huberman Function: https://functionhealth.com/huberman Timestamps 00:00 Glen Jeffery 03:12 Light, Ultraviolet (UV), Visible & Infrared (IR) Light 06:25 Light's Impact on the Body & Light, Sunburn, Cataracts 09:55 UV Light, All-Cause Mortality, Skin Cancer 14:55 Sponsors: Wealthfront & Joovv 17:58 Light Impacts Mitochondria Function & Structure, Long-Wavelength Light (Red/IR), Nano Water 25:00 Long-Wavelength Light Passes Through Clothing & Body; Tissue Scattering 30:08 Long-Wavelength Light & Blood Glucose; Mitochondria 36:19 Red Light, Parkinson's Disease, Cell Death; Eye Rods & Aging; Mitochondria Community 42:46 Red/IR Light, Skull & Brain; Safe Non-Ionizing Radiation 48:22 Sponsors: AG1 & Rorra 51:04 Offsetting Retinal Aging, Improve Vision & Long-Wavelength Light 59:28 Tool: Long-Wavelength Light & Preserve Retinal Mitochondria; Sunlight 1:03:50 Mitochondrial Theory of Aging, Circadian Rhythm & Mitochondria 1:07:57 Tool: Improve Vision with Long-Wavelength Light 1:10:44 Macular Degeneration, Rescuing Vision, Early Intervention 1:13:59 Light Effects at Local vs Distant Tissues, Immune System, Body Communication 1:19:09 Sponsor: Function 1:20:56 Short-Wavelength Light, LED Light, Mitochondria & Serious Health Detriments 1:28:39 Lifespan, LED Lights; Sunlight & Balanced Wavelengths; "Sunlike" Marketing 1:34:45 Fires, Incandescent Lights vs LED Lights, Lasers; Long-Wavelength Devices 1:39:07 Incandescent & Halogen Bulbs, Mitochondria & Built Environments 1:45:19 Windows, Light & Office Work; Screens, Kids & Myopia; Tools: Plants; Lighting 1:55:56 Bring the Outdoors Indoors 2:00:35 Tool: Candlelight; Dim Halogen Lamps 2:05:06 Mitochondrial Diseases, Children & Long-Wavelength Light; Light Bulbs 2:11:53 Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter *This experience may not be representative of other Wealthfront clients, and there is no guarantee of future performance or success. Experiences will vary. The Cash Account, which is not a deposit account, is offered by Wealthfront Brokerage LLC, member FINRA/SIPC.  Wealthfront Brokerage is not a bank. The base APY is 3.50% on cash deposits as of November 07, 2025, is representative, subject to change, and requires no minimum. If eligible for the overall boosted rate of 4.15% offered in connection with this promo, your boosted rate is also subject to change if the base rate decreases during the 3 month promo period. Funds in the Cash Account are swept to program banks, where it earns the variable APY. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer. Investment advisory services are provided by Wealthfront Advisers LLC, an SEC-registered investment adviser. Securities investments: not bank deposits, bank-guaranteed or FDIC-insured, and may lose value. Learn more about your ad choices. Visit megaphone.fm/adchoices

In Episode 266 of the Fit Father Project Podcast, Dr. A sits down with neuroscientist and MitoQ Chief Science Officer, Dr. Siobhan Mitchell, to unpack one of the deepest levers of health for men over 40: your mitochondria. You'll hear how her grandmother's battle with Alzheimer's led her into decades of research on aging, “inflammaging,” and why mitochondrial function sits at the root of brain health, energy, and longevity.Together, they break down how exercise, fasting, MCT oils, CoQ10, vitamin C, and mitochondrial-targeted antioxidants like MitoQ can make the workouts and nutrition you're already doing more effective. You'll learn what the science actually shows in human trials — from better power output and faster recovery to less exercise-induced DNA damage and improved blood vessel growth in working muscles.If you're a busy man who wants more consistent energy, stronger training results, and better protection for your heart, muscles, and brain as you age, this is an essential listen.Key Takeaways:Mitochondria = powerhouses and “CEOs” of the cellOxidative stress & “inflammaging” drive faster agingBalance matters: not too much, not too little mitochondrial activityExercise (especially intervals) trains mitochondrial resilienceFasting & ketones trigger autophagy and longevity pathwaysMCTs (especially C8/C10) support ketones and brain functionCoQ10 is essential but poorly delivered into mitochondria via standard supplementsMitoQ = mitochondria-targeted CoQ10 derivative with human dataStudies: better power output, recovery, and less exercise-induced DNA damageVitamin C, magnesium, B12 often need supplement support with ageNAC, PQQ, NAD boosters, and urolithin A: promising but mixed dataNo magic bullets: stack smart supplements on top of fundamentalsMore About MitoQ and Dr. Siobhan MitchellWebsite: https://www.mitoq.com/On December 1st, go to https://www.mitoq.com/ for a special Cyber Monday offerAfter December 1st, go to https://www.mitoq.com/ and use code FITFAMILY at checkout for 10% off your purchaseFacebook: https://www.facebook.com/MitoQ/Instagram: https://www.instagram.com/mitoq/YouTube: https://www.youtube.com/user/MitoQHealthX: https://twitter.com/Mito_QTik Tok: https://www.tiktok.com/@mitoqPodcast: Cell Me About It https://open.spotify.com/show/2Bbc0Oi5ypbui2voVpnCxf?si=40f849b961d041ffDr. Siobhan Mitchell's Email: smitchell@mitoq.comBiographical Information on Dr. Siobhan MitchellDr. Siobhan Mitchell, PhD is the chief scientific officer of MitoQ with over 25 years of research experience in how nutrition impacts brain aging, metabolic health, and longevity. She completed her PhD at SUNY Albany and a post-doctoral fellowship on brain aging at University of Washington.Siobhan held roles at the three largest food companies in the world...

Parenting a child who goes from calm to chaos in seconds can feel exhausting. You try everything—deep breaths, gentle words, even walking away—and still, the meltdowns come. You're not alone.When kids struggle with big emotions, there's often a hidden root cause inside the body—and minerals play a much bigger role than most parents realize.In this episode, I sit down with Dr. Aaron Hartman to unpack the powerful connection between minerals, mitochondria, and meltdowns—and how nutrition, lifestyle, and nervous system regulation can help your child regain balance and calm.Why does my child melt down when they're “just tired or hungry”?When your child seems to unravel at the smallest thing, it's not bad behavior—it's biology. Mineral imbalances directly affect how their nervous system fires.Low magnesium or zinc deficiency can make the brain more reactive to stress.When blood sugar drops from skipping meals or eating too many processed foods, the body burns through nutrients fast—leading to irritability, anxiety, or panic attacks.A deficient diet full of additives and low in whole foods affects serotonin, dopamine, and other key neurotransmitters.When we calm the brain first and nourish the body, meltdowns start to fade.Takeaway: A balanced diet rich in real food, protein, and calming minerals helps stabilize your child's emotions and energy.Need quick relief while you work on those root causes? Try Quick Calm—my proven method to calm the brain fast so you and your child can reset and start fresh.Could my child's mood swings be linked to mineral deficiencies?Absolutely. Research continues to show how essential minerals affect mental well-being and brain function.Here's what parents need to know:Zinc deficiency is linked with attention deficit disorder (ADD/ADHD), depression, and poor immune function.Magnesium supports relaxation and sleep by calming overactive neurons.B vitamins and vitamin D play a critical role in serotonin production—affecting mood and focus.Too much copper or exposure to heavy metals can worsen anxiety, aggression, and brain fog.HTMA testing (Hair Tissue Mineral Analysis) can reveal these hidden imbalances, helping you target the root cause instead of chasing symptoms.

This week I explore the revolutionary Rice Diet study conducted by Walter Kempner in 1958, which documented the reversal of diabetes and diabetic blindness using a simple diet of white rice, fruit, and sugar. It challenges conventional medical beliefs and highlights the significance of Kempner's findings in the context of diabetes treatment.Kempner W, Peschel RL, Schlayer C. Effect of rice diet on diabetes mellitus associated with vascular disease. Postgrad Med. 1958;24:359-371.------------FREE Nutrition Cheatsheets:https://brian-getleaneatclean.beehiiv.com/subscribeClick to book a FREE 15 minute consult with Brian:https://calendly.com/bdgryn/15min------------Interested in Upgrading your Mitochondria, Improving Energy and Sleep! Check out Troscriptions: https://bit.ly/4ik5kK5Use Discount Code for 10% OFF: EATCLEAN----Watch Get Lean Eat Clean podcast video episodes on YouTube!YouTube.com/@briangryn3680-----How to Take Simple Steps to Reclaim the Body, Energy, and Strength You Had 10-15 Years Ago Using My Stepladder System:https://www.stepladdersystem.com/----B.rad Whey Protein Isolate Superfuel:The Best Protein on The Planet! Available in Two Delicious Flavors: Vanilla Bean and Cocoa BeanUse Coupon Code glec10off for 10% off your order!https://a.co/d/731gssV----My favorite health bars with clean ingredients!https://www.eatprima.com/BRIAN6816310% OFF with this link!

I receive a lot of health questions about how to remedy various debilitating conditions. One of the more concerning questions I receive frequently is regarding kidney failure. Why is there an epidemic of people with failing kidney function? It comes down to mitochondria dysfunction. Instead of focusing in one one study like most health educators do, my goal with these short shows is to paint broad strokes and cover the entire subject from a birds eye view all the way down to the mitochondrial level. Most importantly, as I cover various health conditions in future episodes, I will focus very heavily on the solutions, citing research and mechanisms to back up each of the proposed supplements or protocols. In the case of the kidneys, it comes down to one protein: mitochondrial transcription factor A, or TFAM. When that critical protein inside mitochondria in your kidneys becomes deficient, energy production falls and tissue function decreases, hence, kidney failure. It always comes back to mitochondria. My website: www.matt-blackburn.com Mitolife products: www.mitolife.co Music by George Henner: https://georgehenner.bandcamp.com Two studies I referenced: Mitochondrial Energetics in the Kidneys https://pmc.ncbi.nlm.nih.gov/articles/PMC5965678/#:~:text=The%20kidney%20is%20one%20of,pressure%20in%20the%20glomeruli5. Loss of Mitochondrial Transcription Factor A (TFAM) in Tubule Cells Causes Renal Failure https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3346980  

CRISPR-based gene editing has revolutionized modern biology, but these tools are unable to access the DNA that resides inside mitochondria. Researchers are eager to access and edit this DNA to understand more about the energy production and the mutations that can cause incurable mitochondrial diseases.Because CRISPR can't help with these problems, researchers have been looking for other ways to precisely edit the mitochrondrial genome. And the past few years have brought some success — if researchers can make editing safe and accurate enough, it could eventually be used to treat, and even cure, these genetic conditions.This is an audio version of our Feature: Faulty mitochondria cause deadly diseases — fixing them is about to get a lot easier Hosted on Acast. See acast.com/privacy for more information.

Episode Highlights With JustineHer background in cell membrane medicine and what she learned in thisUnderstanding mitochondria and phospholipids and fatty acidsWhat we don't understand about mitochondria and why they aren't just the powerhouses of the cell and what else they doEinstein: the environment determines how the particle behavesWhat the real biggest needle movers are for healthWhy she tries to use technology outside to minimize the downsidesWe really are a body of water that is regulated by light Mitchondria are sensors and 95-99% of conditions we see today are of mitochondria originThe biggest exposure to human health today is the exposure to non-native EMFs and blue lightLight and dark cycles are foundational for mitochondrial and overall healthWhy we were designed to be connected to natural infrared light (outdoor light) all day longMitochondria actually make subcellular mitochondria Vitamin D is a photoelectric signal that requires light, hydration, redox and more and how a supplement can't replicate this. Taking a supplement doesn't fix a deficiency, it ignores the entire system Why she is vehemently opposed to sunglasses and sunscreen outside of very isolated instances (like skiing and on a boat) and why we want that light on our skin and eyesNeuropsin receptors and why this natural light is so important What redox is- and if you're not able to detox it's because you've lost your voltageHow to support cell membrane and cellular voltage to naturally support redox and detoxMelanin is not just a pigment but a biological semiconductor and heavy metal chelatorWhy a tan is one of the most proactive things we can do in today's world! And melanin is protective against non-native EMFsHow phospholipids are so important and what we don't understand about themWhy it's imperative for us to be in the sunlight for healing How to support our cells with the right fats and why this is so foundationalThe membrane is the brain of the cell and supporting this makes a huge differenceHer take on fish oil and why she would never recommend or consume itIn nature, EPA and DHA are always found within a whole food matrix: fishWhat the cell danger response is and why this matters. The real story on cholesterol: “cholesterol over 200 isn't pathological- it's often a signal of metabolic competence. It's a marker of a nervous system with reserve, of mitochondria still making enough pregnenolone, steroid hormones, and brain lipids.”Resources MentionedMitochondrial Restoration Program Fatty Acid Biochemistry WebinarJustine on InstagramHealthy home lighting

In this episode of the Evolving Wellness Podcast, hosted by Sarah Kleiner, special guest Mateo discusses the remarkable health benefits and advancements in hydrogen therapy. The conversation covers various testimonials, including a woman with severe autoimmune lupus treated at Dr. Allen Inman's clinic in Costa Rica, who experienced life-changing results from using hydrogen therapy. They explore different forms of hydrogen application such as tablets, water, and inhalation, and discuss the technology behind Axiom H2's products. They also dive into hydrogen's role in mitochondrial health, immune system regulation, and potential applications across various medical fields. Mateo shares exciting upcoming advancements for 2024, including a new app and groundbreaking hydrogen technologies.About AxiomAxiom H2™ is pioneering the future of molecular hydrogen technology to optimize health at the cellular level. Their mission is to create the world's most advanced hydrogen delivery systems—engineered to meet medical standards while embodying aerospace precision and durability. Partnering with European R&D experts, doctors, athletes, and global institutions, Axiom H2 combines science, innovation, and purpose to redefine modern wellness. Their vision is to empower people to achieve better vitality, balance oxidative stress, and enhance performance through clean, safe, and effective hydrogen therapyBLACK FRIDAY SALE (get the best discount with code SARAHK) -https://axiomh2.com/ref/6/?wdr_coupon=SARAHKJoin My Circadian App Webinar: https://www.sarahkleinerwellness.com/mycircadianapp-free-webinar DST Guide - https://www.sarahkleinerwellness.com/offers/v5QFAdqz/checkout Quantum Winter Blueprint - https://www.sarahkleinerwellness.com/offers/LS7YHuUF/checkout _________Timestamps00:00 Incredible Testimonial: From Wheelchair to Dancing01:15 Introduction to the Evolving Wellness Podcast01:36 Special Black Friday Announcement04:13 Sarah's Personal Journey with Hydrogen07:30 Understanding Molecular Hydrogen08:32 Different Forms of Hydrogen Therapy10:28 The Importance of Clean Hydrogen25:54 Hydrogen's Role in Cancer and Overall Health29:26 Company Transparency and Global Presence30:30 Addressing Safety Concerns and Misconceptions31:46 Hydrogen's Role in Health and Anti-Aging33:35 Innovative Partnerships and Diagnostic Tools39:24 Hydrogen Therapy and Immune System Modulation43:21 Real-World Success Stories and Testimonials53:35 Future Innovations and Upcoming Releases57:57 Final Thoughts and Holiday Offers________________________________________This video is not medical advice & as a supporter to you and your health journey - I encourage you to monitor your labs and work with a professional!________________________________________Get all my free guides and product recommendations to get started on your journey!https://www.sarahkleinerwellness.com/all-free-resourcesCheck out all my courses to understand how to improve your mitochondrial health & experience long lasting health! (Use code PODCAST to save 10%) - https://www.sarahkleinerwellness.com/coursesSign up for my newsletter to get special offers in the future! -https://www.sarahkleinerwellness.com/contactFree Guide to Building your perfect quantum day (start here) -https://www.sarahkleinerwellness.com/opt-in-9d5f6918-77a8-40d7-bedf-93ca2ec8387fMy free product guide with all product recommendations and discount codes:https://www.sarahkleinerwellness.com/resource_redirect/downloads/file-uploads/sites/2147573344/themes/2150788813/downloads/eac4820-016-b500-7db-ba106ed8583_2024_SKW_Affiliate_Guide_6_.pdf