Podcasts about mitochondria

Welcome to "Thriving in Midlife" The Women's Guide to Wellness, Longevity & Hormones After 40. This is your trusted space to cut through the noise, ditch the overwhelm, and finally feel extraordinary in your body, mind, and life. Are you ready to stop pushing through life and start living it with intention, energy, and ease? Then let's get started. I'm your host, Kellie Lupsha, a high-performance health coach, who is delighted to be your guide to vitality.In this episode, Dr. Heidi and I are diving into a topic that I know so many of you have been asking about: energy. Whether you feel like you're running on empty or you just want to go from an eight to a ten on your energy scale, we are breaking down the secret sauce your body needs. We're talking about those tiny structures inside you called mitochondria, why you aren't lazy even if you feel exhausted, and how we can flip the switch to create a positive feedback loop in our health.Key Highlights:➡️ Why feeling tired in your late 30s, 40s, and 50s is often a systemic change rather than a character flaw.➡️ What mitochondria actually do and why healthy ones equal better energy.➡️ Simple formula involving food and oxygen that your body uses to produce ATP.➡️ Why our mitochondria become less efficient as we age and how hormonal shifts play a role.➡️ The difference between the negative energy loop and the positive feedback loop we want to achieve.➡️ The modern habit that silently interferes with how your body creates energy.➡️ Why moving your body is essential to triggering your energy switches, even when you're tired.➡️ How stress regulation and giving yourself grace can unclog your mitochondrial signals.Key Takeaways:"Mitochondria affect your muscles, your sleep, your brain, your gut… it's the missing secret sauce to energy." - Kellie Lupsha"Laughter, joy, meditation, being around friends that we love, socialization... this is key for a healthy mitochondria." - Dr. Heidi*TAKE THE FREE ~ DISCOVER YOUR MIDLIFE HEALTH BLUEPRINT*****>>> Click Here

In this episode of the Evolving Wellness Podcast, host Sarah Kleiner welcomes back Dr. Scott to discuss the 'sympathetic spiral of doom' and how modern lifestyles contribute to chronic stress and energy depletion. Dr. Scott shares insights into how overstimulation, poor diet, and interrupted sleep cycles can lead to nervous system dysregulation and mitochondrial dysfunction. The conversation covers the importance of circadian rhythm, hydration, and low-hanging fruit lifestyle changes to support overall wellbeing. They also explore the potential benefits of methylene blue, red light therapy, and other practical tools for regaining optimal health. Tune in to learn more about foundational steps to improve energy levels and break free from chronic stress.About Dr. ScottDr. Scott Sherr is a Board-Certified Internal Medicine Physician Certified to Practice Health Optimization Medicine (HOMe), a specialist in Hyperbaric Oxygen Therapy (HBOT), and COO of Troscriptions (a Smarter Not Harder company). His clinical telepractice includes HOMe as its foundation alongside an integrative approach to HBOT that includes cutting edge and dynamic HBOT protocols, comprehensive testing (using the HOMe framework), targeted supplementation, personal practices, synergistic technologies (new, ancient, psychedelic), and moreConnect with Dr. Scott - https://www.linkedin.com/in/drsherr/ _________Sponsored By:→ Bon Charge | Go to https://boncharge.com/products/demi-red-light-device?rfsn=8108115.26608d & use code SARAHKLEINER for 15% off storewide.→ VivaRays | This episode is sponsored by VivaRays - VivaRays Blue - code YOGI https://vivarays.com/ → Organifi | For an exclusive offer, go to https://www.organifi.com/SARAHK for 20% off your order._________Timestamp:00:00 Introduction and Personal Experience with Coffee00:51 Welcome to the Evolving Wellness Podcast03:37 Understanding the Sympathetic Spiral of Doom06:29 The Role of the Nervous System and Mitochondria10:53 Practical Tips for Nervous System Regulation16:53 The Importance of Circadian Rhythm and Light Exposure25:31 Supporting Mitochondrial Health and Energy Production36:17 The State of Metabolic Health in the US36:55 Improving Mitochondrial Function37:27 Addressing Trauma and Sympathetic Overdrive38:31 The Importance of a Supportive Environment40:38 Sleep and Its Impact on Health44:35 The Role of Blue Blockers and Sleep Aids48:21 Caffeine and Its Effects on the Body50:46 The Benefits of Exogenous Ketones58:56 Navigating the Sympathetic Spiral of Doom01:05:14 Final Thoughts and Resources——— This video is not medical advice & as a supporter to you and your health journey - I encourage you to monitor your labs and work with a professional!________________________________________Get all my free guides and product recommendations to get started on your journey!https://www.sarahkleinerwellness.com/all-free-resourcesCheck out all my courses to understand how to improve your mitochondrial health & experience long lasting health! (Use code PODCAST to save 10%) -  https://www.sarahkleinerwellness.com/coursesMy free product guide with all product recommendations and discount codes:https://www.canva.com/design/DAF7mlgZpJI/xVyE4tiQFEWJmh_Xwx8Kbw/view?utm_content=DAF7mlgZpJIFree Webinar on Light & Health (includes free light bulb guide) - https://www.sarahkleinerwellness.com/mycircadianapp-free-webinarGet Early Access to Podcast Episodes & my Seasonal Food Course + UVB+Red Light Therapy course for free -  https://open.substack.com/pub/sarahkleinerwellness/p/uvbred-light-protocol?r=5eztl9&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true

Ramona is a neuroscientist and scientific strategist with deep experience at the intersection of neuroscience, rehabilitation, and emerging health technologies. She earned her BS in Psychology from Brown University, her PhD in Neuroscience from the Uniformed Services University (where her research focused on the modulation of inflammation following Neurotrauma, including publications on the impact of photobiomodulation on microglial activation), and she completed a postdoctoral fellowship in the Neurology Department at the University of Texas at Austin Dell Medical School.Ramona is the Senior Director of US Medical Affairs for Winback America, and serves as a Scientific Advisor for two start ups, Neuronic and the Brainnovation Network. She specializes in translating complex science into real-world clinical and commercial outcomes — from leading research and publication efforts to building clinician training programs. In these roles, she oversees clinical research, education, and regulatory positioning. At Neuronic specifically, she supports research efforts to demonstrate the efficacy of transcranial photobiomodulation on cognitive function and a variety of neurological conditions.She is passionate about leveraging technology to help people achieve their highest quality of life and brings a practical, collaborative approach to connecting science, clinical practice, and business strategy. SHOWNOTES:

What if your breakthrough isn't another supplement or hormone protocol, but a personalized understanding of what's actually driving your results?In this episode of the Smart Nutrition Made Simple Show, I talk with Brad Clifford, founder and CEO of ELEVÉTION Health, a concierge performance company built around genomics, advanced blood work, and cellular health. Brad shares how he went from panic attacks and brain fog to rebuilding his health from the cellular level up.We break down the two-pronged nature of health, psychological and physiological, why sleep is the ultimate force multiplier, and why no supplement, peptide, or TRT protocol can replace foundational habits. We also dive into metabolic flexibility, mitochondrial health, GLP-1 drugs, and why most people regain the weight when they come off them.Tune in now to build a smarter, more sustainable strategy for long-term performance and longevity.Timestamps:00:00 – Why GLP-1 Drugs Feel So Powerful 01:44 – Episode Intro 03:26 – Who Is Brad Clifford? 07:03 – The Two Prongs of Health 08:25 – Sleep, Nutrition & Exercise Foundations 12:25 – Brad's Health Struggles & Panic Attacks 15:30 – Genomics & Brain Chemistry 21:44 – How Elevation Differs from Typical Clinics 24:41 – Why “Stacks” Don't Work 28:30 – Mitochondria & NAD 31:51 – Metabolic Flexibility 34:52 – Carnivore & Long-Term Tradeoffs 39:27 – Addition by Subtraction 40:00 – Sleep & Injury Risk 41:30 – Psychology of Transformation 43:00 – GLP-1 Weight Regain 46:17 – Future Casting & Identity 51:05 – UK Expansion 52:01 – Where to ConnectConnect with Brad CliffordWebsite: https://www.elevetion.comInstagram (Elevation): https://www.instagram.com/elevetionhealth/Instagram (Brad): https://www.instagram.com/brad_cliffordLinks & Resources:Connect with Ben on Instagram: https://www.instagram.com/bodysystemscoaching/Learn more about Ben's coaching program: www.bodysystems.comSubscribe to the Smart Nutrition Made Simple Show on Apple Podcasts -

Send a textIn episode #174 we discussed Dr. Jose Areta's latest research, including:How energy deficits influence muscle protein synthesis and qualityThe role of mitochondrial proteins and their upregulation during energy restrictionPractical implications for timing and periodization of caloric deficits in training cyclesHormonal signals and their interaction with muscle adaptation during energy deficitsAssociate Professor Dr. José L. Areta is a leading scholar in Exercise Metabolism and Nutrition in the School of Sport and Exercise Sciences at Liverpool John Moores University (LJMU). His research investigates how nutrition and exercise interact to influence both performance and health. He focuses on the timing and composition of macronutrients — carbohydrates, proteins, and fats — and how they affect training adaptation. José also examines the role of dietary supplements in optimizing athletic performance, as well as the endocrine and metabolic consequences of energy restriction, particularly low energy availability. He has contributed influential studies on how severe calorie deficits combined with exercise can alter muscle quality and metabolism. José's work links cellular-level changes in muscle to practical nutrition strategies for athletes facing weight-sensitive sports or energy restriction.Please note that this podcast is created strictly for educational purposes and should never be used for medical diagnosis or treatment.Follow Jose Areta's research: Study discussed, Endocrine, Metabolic, and Skeletal Muscle Proteomic Responses During Energy Deficit With Concomitant Aerobic Exercise in Humans: https://faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202502384RRIG: https://www.instagram.com/jose_l_aretaWeb: https://profiles.ljmu.ac.uk/13460-jose-aretaResearch: https://scholar.google.com/citations?user=8tP0vzUAAAAJ&hl=enMentioned:A Systematic Review and Meta-Analysis on the Association and Differences between Aerobic Threshold and Pint of Optimal Fat OxidationCreatineBeta-alanineMORE NR Save 10% on our website with code NEWPOD10 Apply to work with us, click here: https://nutritional-revolution.com/ Interested in having your biomarkers or nutrigenomics checked? Email us at nutritionalrev@gmail.com Follow us @nutritionalrevolution Save 20% on supplements at our trusted online source: https://us.fullscript.com/welcome/kchannell Join Nutritional Revolution's The Feed Club to get $20 off with an additional $20 Feed credit drop every 90 days.: https://thefeed.com/teams/nutritional-revolution If you're interested in sponsoring Nutritional Revolution Podcast, shoot us an email at nutritionalrev@gmail.com.

This week I interviewed the king of the mattress - Derek Hales! Since 2013, Derek has tested over 500 mattresses and founded NapLab, a platform that takes a truly data-driven approach to sleep products. His methodology goes far beyond surface impressions; instead, every mattress is subjected to 10 standardized tests with 43 measurable data points, so people can learn how cooling, motion isolation, and edge support actually impact their sleep and health. We discuss the importance of the weight of your mattress is along with:  - What is the best mattress to maintain your cool throughout the night- Is memory foam worth the hype?- Should you rotate your mattressand much, much more!!Connect with Derek:https://naplab.com/-----------------How to Take Simple Steps to Reclaim the Body, Energy, and Strength You Had 10-15 Years Ago Using My Stepladder System:https://www.stepladdersystem.com/FREE Nutrition Cheatsheets:https://brian-getleaneatclean.beehiiv.com/subscribeClick to book a FREE 15 minute consult with Brian:https://calendly.com/bdgryn/15min------------Interested in Upgrading your Mitochondria, Improving Energy and Sleep! Check out Troscriptions: https://bit.ly/4ik5kK5Use Discount Code for 10% OFF: EATCLEAN----Watch Get Lean Eat Clean podcast video episodes on YouTube!YouTube.com/@briangryn3680----B.rad Whey Protein Isolate Superfuel:The Best Protein on The Planet! Available in Two Delicious Flavors: Vanilla Bean and Cocoa BeanUse Coupon Code glec10off for 10% off your order!https://a.co/d/731gssV----My favorite health bars with clean ingredients!https://www.eatprima.com/BRIAN6816310% OFF with this link!

Angela talks to Ari Whitten, the founder of The Energy Blueprint and an expert in mitochondrial health about his comprehensive approach to overcoming fatigue and optimising energy levels by addressing the cellular engines of the body—the mitochondria.  Ari explains how modern lifestyle factors, such as poor light exposure, chronic stress, and nutritional deficiencies, signal the mitochondria to enter a defence mode rather than an energy-producing mode WHAT YOU'LL LEARN: The Cell Danger Response (CDR): Mitochondria have a dual role; they are not just energy producers but also environmental sensors that shift into a defensive state when they perceive threats Circadian Rhythm and Light: Proper exposure to natural light in the morning and minimising artificial blue light at night is critical for regulating the mitochondrial clock and ensuring deep, restorative sleep. Hormetic Stress: Introducing controlled stressors—such as high-intensity exercise, cold exposure, or heat—can actually strengthen mitochondria and increase their capacity to produce energy The Importance of Nutrient Density: Specific nutrients, including CoQ10, magnesium, and polyphenols, are essential "fuel" for the electron transport chain TIMESTAMPS [00:04:15] The "Energy Gap" [00:18:30] Mitochondria as Sensors [00:32:45] The Power of Red Light Therapy [00:52:10] Building Metabolic Flexibility VALUABLE RESOURCES ⁠Join The High Performance Health Community⁠ ⁠Click here⁠ for discounts on all the products I personally use and recommend A BIG thank you to our sponsors who make the show possible The Ultimate Guide to Red Light Therapy  Find out your biological age and how your daily habits are influencing it with DNA, bloodwork and microbiome testing with a Stride One membership - visit https://www.getstride.com/angela/ for 10% off. Ready to support your body at the cellular level where it matters? Head to www.MitoQ.com and use my code ANGELA for 10% off your first order *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. ABOUT THE HOST Angela Foster is an award winning Nutritionist, Health & Performance Coach, Speaker and Host of the High Performance Health podcast. A former Corporate lawyer turned industry leader in biohacking and health optimisation for women, Angela has been featured in various media including Huff Post, Runners world, The Health Optimisation Summit, BrainTap, The Women's Biohacking Conference, Livestrong & Natural Health Magazine. Angela is the creator of BioSyncing®️ a blueprint for ambitious entrepreneurial women to biohack their health so they can 10X how they show up in their business and their family without burning out. CONTACT DETAILS ⁠Instagram⁠ ⁠Facebook⁠ ⁠LinkedIn⁠ Disclaimer: The High Performance Health Podcast is for general information purposes only and do not constitute the practice of professional or coaching advice and no client relationship is formed. The use of information on this podcast, or materials linked from this podcast is at the user's own risk. The content of this podcast is not intended to be a substitute for medical or other professional advice, diagnosis, or treatment. Users should seek the assistance of their medical doctor or other health care professional for before taking any steps to implement any of the items discussed in this podcast. This Podcast has been brought to you by Disruptive Media. ⁠https://disruptivemedia.co.uk/

You've treated the pain. You've tracked the triggers. You've adjusted food, sleep, and stress and yet migraines keep finding a way in.What if the missing piece isn't in your head… but in your metabolism?In this episode of Migraine Heroes Podcast, host Diane Ducarme explores one of the most overlooked drivers of migraine: the thyroid. Not as a single lab value, but as a system that sets the rhythm for your brain, your nervous system, and your tolerance to pain.The thyroid doesn't just influence weight or energy. It acts as a metabolic pacemaker, shaping blood flow, heat production, neurotransmitter balance, and stress resilience. When that rhythm slows or becomes unstable, the migraine brain becomes far more reactive — even to triggers that once felt manageable.Blending modern neuroscience with an Eastern medicine lens, this episode unpacks why migraines often show up alongside fatigue, coldness, brain fog, pressure headaches, and that persistent feeling of running on empty.In this episode, you'll learn:Why the thyroid functions as the metabolic pacemaker for the brain and how a slowed rhythm lowers your migraine thresholdHow reduced internal “fire” contributes to dampness, heaviness, and pressure in the headFive subtle yet powerful ways a struggling metabolism signals the nervous system to trigger migraineWhy thyroid-linked migraines often feel slower, heavier, and harder to shakeHow restoring rhythm, warmth, and flow can change how your migraine brain respondsThis episode isn't about diagnosing disease or blaming a single gland. It's about understanding the deeper patterns your body is communicating and responding before those whispers become pain.If your migraines come with fatigue, cold sensitivity, brain fog, or a sense that your system just can't keep up anymore, this conversation may finally bring clarity.

Send a textThe biology of fat tissue, estrogen's role in metabolism and health, and how exercise interacts with these processes, especially during menopause.TOPICS DISCUSSED:Adipose tissue basics: White fat primarily stores energy in large lipid droplets, while brown fat burns fatty acids for heat via high mitochondrial density; white fat can “brown” with exercise or certain foods like capsaicin.Fat distribution & health: Subcutaneous fat (under skin) is more insulin-sensitive and less problematic than visceral fat (around organs), which links to metabolic issues; females store more subcutaneously pre-menopause, shifting to visceral post-menopause.Estrogen signaling: Estradiol binds nuclear and membrane receptors to regulate gene expression and mitochondrial function; it enhances insulin sensitivity and browning in fat cells, with receptors like ER-alpha feminizing fat distribution.Fat storage: Fat cells enlarge (hypertrophy) more than multiply in obesity, leading to hypoxia, inflammation, and insulin resistance; excess fatty acids spill to liver and muscle, worsening metabolic dysfunction.Menopause effects: Estrogen drop causes visceral fat gain, reduced energy expenditure, insulin resistance, and higher metabolic disease risk; symptoms include hot flashes and reduced exercise motivation, modeled in rodents via ovary removal.Exercise & estrogen links: Exercise boosts estrogen receptor expression and mitochondrial density in fat, mimicking estrogen's browning effects; synergism may explain reduced exercise responsiveness post-menopause.Brain-fat connections: Estrogen in the nucleus accumbens influences exercise motivation and fat browning; manipulations there alter running behavior and adipose metabolism in rodents.ABOUT THE GUEST: Victoria Vieira-Potter, PhD leads a lab at the University of Missouri, studying how estrogen and exercise influence adipose cells.RELATED EPISODE:M&M 174 | Adipose Tissue & Body Fat: Obesity, Insulin, Leptin, Fertility, Weight Loss & GLP-1 Drugs | Sean HartigSupport the showHealth Products by M&M Partners: SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off. Lumen device: Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts

Today's conversation dives deep into hormone health and the myths surrounding testosterone therapy, featuring Shalin Shah, CEO of Marius Pharmaceuticals, and guided by host Chris Duffin with contributions from Anthony, our co-host. We'll explore the stigmas and misconceptions attached to testosterone treatments, the groundbreaking launch of Kaisertrex (an FDA-approved oral testosterone capsule), and why hormone diagnostics matter for both men and women. Shalin Shah shares his journey as a passionate advocate for gender equity in hormone care and discusses how lifestyle, environmental factors, and stress impact hormone levels—especially as more young people experience low testosterone.  

In this episode, I sit down with Daria Mochly-Rosen to explore the powerful role mitochondria play in our energy, brain health, metabolism, and long term resilience. We talk about the science behind sleep, strength training, stress, and nutrition, and how simple daily habits can support better healthspan without falling into burnout or extreme biohacks.We also cover the cultural pressure to hustle nonstop, why slowing down is not a weakness, and how connection, family, and meaningful conversations can actually support your biology. She breaks down the fascinating truth about how we inherit mitochondria, how lifestyle choices influence cellular health, and why it is never too late to start building stronger, more resilient energy from the inside out.→ Leave Us A Voice Message! Topics Discussed:→ What are mitochondria?→ How to boost energy?→ Does sleep affect health?→ Best habits for longevity?→ Are mitochondria inherited?Sponsored By: → Function | Own your health for $365 a year. That's a dollar a day. Learn more and join using my link. Visit https://www.functionhealth.com/bewellbykelly and use gift code BEWELL25 for a $25 credit toward your membership→ Be Well By Kelly Protein Powder & Essentials | Get $10 off your order with PODCAST10 at https://bewellbykelly.com.→ Timeline | Support your cells and how you age with Mitopure® Gummies from Timeline. Visit https://timeline.com/KELLY and save up to 39% off your Mitopure® Gummies.→ Fatty 15 | Fatty15 is on a mission to replenish your C15 levels and restore your long-term health. You can get an additional 15% off their 90-day subscription Starter Kit by going to https://fatty15.com/KELLY15 and using code KELLY15 at checkout.Timestamps: → 00:00:00 - Introduction→ 00:01:57 - What are mitochondria?→ 00:02:48 - Mitochondria in each cell→ 00:03:46 - Krebs cycle, ATP + metabolism→ 00:06:24 - Cellular energy production→ 00:08:22 - Nutrition for energy→ 00:14:08 - Healthy vs refined carbs→ 00:17:05 - Sugar + metabolic health→ 00:19:12 - Fad diets explained→ 00:23:45 - Lifestyle changes for longevity→ 00:30:33 - Stress + mitochondrial health→ 00:35:59 - Mitophagy + autophagy benefits→ 00:40:46 - Glymphatic brain detox→ 00:43:09 - Exercise + movement science→ 00:49:10 - Mitochondrial peptides→ 00:55:16 - MOTS-C peptide benefits→ 00:56:35 - Chronic disease + mitochondria→ 01:02:38 - Reactive oxygen species→ 01:07:36 - Family, connection + health→ 01:12:07 - Fertility + energy health→ 01:15:01 - Building healthy mitochondriaFurther Listening: → The Key to Longevity: Exploring Mitochondrial Uncoupling with Dr. Steven GundryCheck Out Daria:→ Stanford | https://med.stanford.edu/profiles/daria-mochly-rosen→ Linkedin | https://www.linkedin.com/in/daria-mochly-rosen-9733bb198→ Book |

Modern humans are living in an environment radically different from the one our biology evolved to operate within. In this conversation, we explore how light, mitochondria, evolution, and physics shape aging, disease, mental health, and longevity. This episode reframes health not as a matter of isolated interventions, but as the consequence of whether we remain inside—or drift outside—the human biological envelope.Dr Alistair Nunn is the Director of Science of The Guy Foundation Family Trust and Visiting Professor in Theoretical Quantum Biology & Bioenergetics Research Centre for Optimal Health at the University of Westminster, London, UK. SUPPORT MY WORK

In this episode of Beauty Bytes, I sit down with Courtney Van Bussum, the Chief Operating Officer of Longevity Launch Labs, an innovation incubator dedicated to translating cutting-edge cellular science into real-world medical solutions. We go way beyond the basics to explore the mitochondria—the ancient, alien-like "batteries" living inside our cells that power everything from our heartbeat to our collagen production .Courtney explains why mitochondrial dysfunction is actually the root cause of aging symptoms we hate, like brain fog, skin dullness, and even gray hair (did you know gray hair is just your follicle running out of energy to produce pigment?) . We discuss the concept of hormesis—using good stress like exercise and intermittent fasting to make your cells stronger—and why you might need to "starve" your cells at night to help them repair.We also get into the nitty-gritty of supplementation. We break down why 1-MNA might be safer than aggressive NAD+ IV drips, why creatine isn't just for bodybuilders (it's a brain and beauty super-fuel!), and the emerging world of mitochondrial peptides like SS-31.

In this episode, Dr. Greg Jones sits down with Dr. Sharon Hausman-Cohen, Chief Medical Officer of IntelliXX DNA, to explore how medical genomics is transforming the way we understand heart disease, brain health, inflammation, and metabolism. Most people think genetics stops at traits like eye color or ancestry. Genomics goes much deeper—analyzing how thousands of genes interact to influence cardiovascular risk, cognitive function, clotting tendencies, nutrient metabolism, and chronic inflammation.Dr. Hausman-Cohen explains why many direct-to-consumer DNA tests fall short, how incomplete interpretation can mislead patients, and why clinician-guided genomic analysis allows for truly personalized care. The conversation also dives into inflammation, methylation, homocysteine, cholesterol myths, caffeine metabolism, mitochondrial health, and women's unique clotting risks.Whether you're trying to reduce your risk of heart disease, improve mental clarity, or understand how your biology responds to diet, supplements, and medications—this episode offers a science-based roadmap for precision health.

This episode is brought to you by Troscriptions and Strong Coffee Company. What if the smallest molecule in the universe could have the biggest impact on your health? Welcome "Greg the Hydrogen Man" to explore the science, controversy, and real-world application of hydrogen water and molecular hydrogen therapy. This conversation goes beyond hydration — it explores how hydrogen acts as a biological signal, how it interacts with oxygen, and why it may be foundational to cellular health. Whether you're into biohacking, longevity, performance, or holistic health, this episode will challenge how you think about water and what it means to truly nourish the body. ----- 00:00 – Why water can heal… or harm 02:30 – Why most hydrogen devices are problematic 05:00 – Japan's longevity advantage explained 07:45 – Hydrogen, gut health, and gas signaling 10:00 – What hydrogen water actually is 14:00 – The healing waters of Lourdes & hydrogen discovery 17:30 – Why hydrogen is different from all antioxidants 19:30 – Mitochondria, oxidative stress & disease 22:45 – Hydrogen and stroke recovery in Japan 26:30 – Why clean water matters before hydrogen 30:00 – Live blood analysis: clean water vs hydrogen water 33:30 – How hydrogen acts as a cellular signal 36:00 – Morning hydrogen water protocol 40:30 – The Japanese hydrogen machine origin story 43:00 – How long before people feel results 45:30 – Safety, medications & contraindications 48:30 –Ever Forward ----- Episode resources: Try Calm by Troscriptions and use checkout code EVERFORWARD Save 15% on organic coffee and lattes with code CHASE at https://www.StrongCoffeeCompany.com Watch and subscribe on YouTube Greg's YouTube channel

Dr. Khambatta introduces mitochondria, explains their role in energy production, shares his personal autoimmune journey, and traces the evolutionary history that made complex life possible. #Mitochondria #ChronicDisease #Autoimmunity #HealthTalks

Most parents are told ADHD lives only in the brain, but what if the real issue starts much deeper? In this episode, we explore a powerful and often overlooked driver of ADHD symptoms: mineral depletion at the cellular level. You'll hear why calm, focus, sleep, and emotional regulation are literally built from minerals and how many kids are trying to regulate big emotions while running on empty batteries. Dana Kay is joined by Caroline Alan, co-founder of Beam Minerals and author of The Mineral Reset, to break down complex biology into parent-friendly language. Caroline explains how minerals fuel the mitochondria — the tiny "campfires" inside every cell — and why children who lack proper mineral support can appear anxious, wired, exhausted, or stuck in fight-or-flight, even when they eat a "healthy" diet. This conversation helps parents understand why food quality, soil depletion, filtered water, and modern stressors have created a widespread mineral gap — and what gentle, practical steps families can take to support their child's nervous system without overwhelm. If your child struggles with meltdowns, sleep issues, anxiety, or focus, this episode offers a new lens grounded in biology, not behavior. LINKS MENTIONED IN THE SHOW https://beamminerals.com/adhdthrive https://mineralresetbook.com Discount Code: ADHDTHRIVE Connect with Caroline Alan Website: www.carolinealan.com Instagram: https://www.instagram.com/carolinealan.official/ YouTube: https://www.youtube.com/@carolinealan.official KEY TAKEAWAYS [00:00] ADHD symptoms as signs of depletion [03:48] Why minerals matter beyond bones and teeth [08:41] Mitochondria, energy, and brain function [11:05] Low energy cells and nervous system stress [21:10] Soil depletion and food mineral loss [23:31] How filtered water worsens deficiency [30:22] Humic vs. fulvic minerals explained [38:05] Minerals as spark plugs for the brain [44:51] One simple step parents can take today MEMORABLE MOMENTS "Our kids are not being difficult — they're depleted." "Calm is built from minerals." "Minerals are the spark plugs for the brain." "That equals a kid who cannot sit down." "You cannot eat your way out of mineral deficiency." "This isn't ADHD behavior — it's biology." Dana Kay Resources:

When cellular energy production is impaired, no diet, supplement, or health protocol can work as intended.In this episode, Dr. Chris Masterjohn, nutrition scientist and expert in micronutrients and metabolism, explains why mitochondrial function is the limiting factor behind stalled progress, persistent fatigue, and supplements that stop working over time.He breaks down why vitamin D supplementation often creates new problems when it is taken without proper nutrient balance, how high doses can disrupt other systems in the body, and why sunlight has biological effects that vitamin D pills alone cannot replicate.Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women's health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you'll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women.https://kayla-barnes-lentz.circle.so/checkout/become-a-memberThis conversation explores:Why mitochondrial bottlenecks explain most energy and health plateausHow micronutrient deficiencies undermine supplements and biohacksWhen creatine supports cellular energy and why it works differently than most supplementsWhy vitamin D supplementation can backfire without context and balanceWhy sunlight affects biology in ways supplements cannot replaceHow diet, fasting, and exercise interact with mitochondrial capacityWhy optimizing one system often breaks another without proper foundationsConnect with Kayla:Instagram: https://www.instagram.com/kaylabarnes/TikTok: https://www.tiktok.com/@femalelongevityTwitter:https://x.com/femalelongevityWebsite:https://www.kaylabarnes.com/Spotify:https://open.spotify.com/show/4OLWWn22...Apple: https://podcasts.apple.com/us/podcast...Follow Her Female Protocol: https://www.protocol.kaylabarnes.comLearn more about Dr Chris Masterjohn's work:Website: https://www.chrismasterjohn-phd.com/Instagram: https://www.instagram.com/chrismasterjohn/YouTube: https://www.youtube.com/@chrismasterjohn

We discuss three pivotal studies showing how natural light wavelengths positively influence health from all-cause mortality to visual perfomance to blood glucose control in Type II diabetics.Jonathan Jarecki is a biomedical science sophomore with an interest in light and health, and host of Whole Health Podcast. SUPPORT MY WORK

Dr. Catherine Clinton shares her journey into the growing field of quantum biology that led to her book, Optimize, that explains how light, water, sound and human energy influence the human body at the cellular level, this week on Spirit Gym.Learn more about Catherine's work on her website. Find her on social media via Facebook, Instagram and YouTube.Order Catherine's book, Optimize, and receive more than $400 in free bonuses, including her Quantum Biology Masterclass and her Unlocking Your Quantum Biology course at this link.Timestamps6:51 Catherine's introduction to natural medicine.10:48 Psychoneuroimmunology.19:25 Quantum biology: Waves that hold energy and information.27:21 The electrical capacity of the human body and how pain emerges.34:19 pH balance and a positive charge in the body.48:04 What is the source of electrical currents in nature and humans?57:08 The fascia as a liquid crystalline semiconductor that can create its own charge.1:08:39 When Catherine went all in on quantum biology.1:15:59 Nurturing a relationship with the natural world is one of the most overlooked ways to elevate our health.1:26:17 “We don't end at the barriers of our skin.”1:32:32 Tantra and the Nada Bindu point.1:41:07 The physical receiver.1:47:08 “Use your heart to feel what you know.”1:53:26 Water: The bridge for frequency information.2:03:16 “Awe is medicine.”2:11:04 Digging deeper into the mitochondria.2:27:47 Did you know each of us can communicate with the universe via infrared light transmission?ResourcesWhat is Life? by Erwin SchrodingerWater, The Cradle of Life via its Coherent Quantum Frequencies by Hans Geesink, Dirk Mejier and Igor Jerman (free PDF)Adenosine triphosphate (ATP)Electric Body, Electric Health by Eileen McKusickFind more resources for this episode on our website.Music Credit: Meet Your Heroes (444Hz), Composed, mixed, mastered and produced by Michael RB Schwartz of Brave Bear MusicThanks to our awesome sponsors:PaleovalleyBIOptimizers US and BIOptimizers UK PAUL15Organifi CHEK20Wild PasturesKorrect SPIRITGYMPique LifeCHEK Institute We may earn commissions from qualifying purchases using affiliate links.

Oh hey y'all.I have wanted to have this conversation for a long time, and Dr. Scott Sherr absolutely delivered.We get into what mitochondria actually do, why almost all of us are dealing with some level of dysfunction, and how energy production sits at the center of mental clarity, recovery, stress resilience, and overall health.This is one of those episodes that completely shifts how you think about your body.We also talk about methylene blue, why the internet both loves and fears it, and how to think about nervous system training, oxygen therapy, and health optimization without getting overwhelmed.This one is science heavy but incredibly practical, and honestly, I did not want it to end.Highlights:(03:09) Why mitochondria might be the missing link in modern health(09:08) The real reasons energy production breaks down over time(16:18) What health optimization medicine actually means in practice(20:30) Methylene blue explained without the hype or fear(36:25) Hyperbaric oxygen therapy, when it helps and when it does not(42:05) Building health long term while still feeling better nowConnect with Dr Scott:https://www.linkedin.com/in/drsherr/ https://www.linkedin.com/company/troscriptions/ https://www.linkedin.com/company/onebasehealth/https://www.instagram.com/troscriptions/ https://www.instagram.com/drscottsherr/https://www.instagram.com/onebasehealth/ https://www.instagram.com/homehopeorg/Qualia Mind - click hereCoupon Code: SHOCKANDYALL (15% off any purchase)Visit Nicole's on demand fitness platform for live weekly classes and a recorded library of yoga, strength training, guided audio meditations and mobility (Kinstretch) classes, as well: https://www.sweatandstillness.comGrab Nicole's bestselling children's book and enter your email for A FREE GIFT: https://www.yolkedbook.comFind Nicole on Instagram:https://www.instagram.com/nicolesciacca/Tik Tok: https://www.tiktok.com/@thenicolesciaccaFacebook: https://www.facebook.com/nicolesciaccayoga/Youtube:https://www.youtube.com/channel/UC1X8PPWCQa2werd4unex1eAPractice yoga with Nicole in person in Santa Monica, CA at Aviator Nation Ride. Get the App to book in: https://apps.apple.com/us/app/aviator-nation-ride/id1610561929Book a discovery call or virtual assessment with Nicole here: https://www.calendly.com/nicolesciaccaThis Podcast is proudly produced by Wavemakers Audio

This week I interviewed Santiago Brand. He is an international educator and consultant in brain mapping and neurofeedback, helping professionals, high performers, and everyday individuals use neuroscience to optimize mental health, focus, and resilience.  Santiago combines deep technical expertise with engaging, real-world examples, offering a rare blend of science and practical tools you can use to think more clearly, recover faster from stress, and sustain peak performance in work, sport, and life.Connect with Santiago:https://www.santiagobrand.com/-----------------How to Take Simple Steps to Reclaim the Body, Energy, and Strength You Had 10-15 Years Ago Using My Stepladder System:https://www.stepladdersystem.com/FREE Nutrition Cheatsheets:https://brian-getleaneatclean.beehiiv.com/subscribeClick to book a FREE 15 minute consult with Brian:https://calendly.com/bdgryn/15min------------Interested in Upgrading your Mitochondria, Improving Energy and Sleep! Check out Troscriptions: https://bit.ly/4ik5kK5Use Discount Code for 10% OFF: EATCLEAN----Watch Get Lean Eat Clean podcast video episodes on YouTube!YouTube.com/@briangryn3680----B.rad Whey Protein Isolate Superfuel:The Best Protein on The Planet! Available in Two Delicious Flavors: Vanilla Bean and Cocoa BeanUse Coupon Code glec10off for 10% off your order!https://a.co/d/731gssV----My favorite health bars with clean ingredients!https://www.eatprima.com/BRIAN6816310% OFF with this link!

Mitochondria, Metabolism & Modern Medicine   When "Everything Looks Normal"… But You Don't Feel Normal The Cellular Health Conversation Most People Never Get Why Your Energy, Hormones, and Metabolism Start at the Mitochondria   You can be "doing everything right"… and still feel wiped out by 2 p.m.  You can have "normal" labs… and still feel like something is off.    In this episode of Richer Soul, Rocky sits down with Dr. William Haas to explore what modern medicine often misses: cellular dysfunction, mitochondrial health, gut integrity, hormones, toxins, and recovery tools like hyperbaric oxygen—especially for high performers who hit the wall despite clean living.  "Medical school is teaching how to manage disease. And that was a rude awakening."    5 Soul-Level Insights from Dr. William Haas: (This isn't about chasing more hacks. It's about understanding what your body is telling you.)  Mitochondria aren't just "energy." Dr. Haas explains mitochondria produce ATP (your energy currency) and influence inflammation and immune pathways—so mitochondrial dysfunction can ripple into far more than fatigue.  Some "normal" meds can quietly derail cellular performance. He specifically calls out antibiotics like Cipro and Levoquin as "terrible" for mitochondrial health, notes OTC anti-inflammatories can "uncouple" mitochondria, and discusses metformin potentially impacting mitochondria and contributing to B12 deficiency.  Food sensitivities may be a symptom, not the root cause. When people "light up like a Christmas tree" on food sensitivity testing, Dr. Haas says it often points to gut barrier issues ("leaky gut")—and that fixing the gut can make sensitivities go away.  Hormones don't fail in isolation—stress and sleep shape the outcome. He emphasizes starting with fundamentals like sleep, alcohol reduction, and stress management, and explains "cortisol steal" where high stress drives cortisol production at the expense of testosterone.  Metabolism isn't magic: build lean muscle. When asked how to increase metabolic rate, Dr. Haas gives the simplest (and most effective) answer: build lean muscle mass.    Why This Conversation Matters: Dr. Haas shares that in his 40s—while scaling his medical practice, starting another business helping other doctors, and growing his family—fatigue hit hard, even while he was "doing the right things." It became a wake-up moment that something at a cellular level was off.  That experience pushed him deeper into what he describes as cellular medicine: mitochondria, redox/repair pathways, hormones, toxins, and tools like hyperbaric oxygen.  And it highlights a hard truth for high performers: If your health collapses, your freedom collapses with it.    Money Learning: Dr. Haas also touches a reality most people don't think about: Becoming a doctor can delay earning for a long time. He says he was about 38 when he made his first "real" doctor paycheck—and contrasts that with his brother who started earning right after college.  Rocky adds an important point: sometimes the best decisions happen outside the traditional insurance-driven system—when you can get proactive testing and establish baselines, rather than waiting until the system says you're "sick enough" to qualify.    Key Takeaway: If you want more energy, better recovery, and a longer health span, you can't only focus on symptoms—you have to protect the foundations: mitochondria, gut function, hormones, and lean muscle mass.    Guest Bio: Dr. William Haas: Dr. William Haas is trained in family practice and describes his path into integrative medicine, which he frames as focusing on prevention, food as medicine, the mind-body connection, and pulling tools from different healing modalities. He also mentions training/mentorship with Andrew Weil.  In this episode, he discusses deeper evaluation beyond basic labs, including gut function/microbiome, micronutrients, hormones, inflammation, and toxins such as mycotoxins/mold, microplastics, and heavy metals.    Links: Website: https://vyvewellness.com/ Facebook: https://www.facebook.com/VYVEWellness/ Instagram: https://www.instagram.com/vyvewellness YouTube: https://www.youtube.com/@VYVEWellness Blog: https://vyvewellness.com/blog/   Ready to Go Deeper? Stop accepting "everything looks normal" as the end of the conversation. If you want to identify your own detox, redox, and repair blind spots, start with the free assessment at vyvewellness.com.   #RicherSoul #DrWilliamHaas #Mitochondria #MitochondrialHealth #Metabolism #LeanMuscle #FunctionalMedicine #IntegrativeMedicine #GutHealth #LeakyGut #HormoneHealth #Testosterone #HyperbaricOxygen #HBOT #Longevity #HealthOptimization    Watch the full episode on YouTube: https://www.youtube.com/@richersoul Richer Soul Life Beyond Money. You got rich, now what? Let's talk about your journey to more a purposeful, intentional, amazing life. Where are you going to go and how are you going to get there? Let's figure that out together. At the core is the financial well-being to be able to do what you want, when you want, how you want. It's about personal freedom! Thanks for listening! Show Sponsor: http://profitcomesfirst.com/ Schedule your free no obligation call: https://bookme.name/rockyl/lite/intro-appointment-15-minutes If you like the show please leave a review on iTunes: http://bit.do/richersoul https://www.facebook.com/richersoul http://richersoul.com/ rocky@richersoul.com Some music provided by Junan from Junan Podcast Any financial advice is for educational purposes only and you should consult with an expert for your specific needs.

Get Dr. Vonda's latest insights on strength, bone health, longevity, and aging with power delivered straight to your inbox. Join her free health & longevity newsletter here: https://www.drvondawright.com/resources/aging-longevity Today I want to talk with you about how women age, and why so many of us feel surprised by what happens to our bodies in midlife.   This is not an episode about chasing youth or fearing wrinkles. It is about understanding why women are not taught how longevity really works in our bodies, and why the years leading up to menopause matter far more than we were ever told. I have learned, through decades of caring for women as an orthopedic sports surgeon, that we are not simply smaller versions of men. Our biology has often been overlooked in longevity research, even though estrogen quietly influences nearly every system that determines how strong, mobile, and independent we remain as we age. I want you to know this. Aging is not something that happens to you. It is something you can shape. With the right information, a few consistent habits, and a deeper understanding of your own body, you can build strength and resilience that carry you forward for decades.   If you have ever felt like your body changed without warning, like the advice that once worked no longer does, or like aging has been framed as something to fear, this episode is for you. My hope is that this conversation leaves you feeling informed, supported, and empowered to age with strength, clarity, and confidence.   Timestamps 00:00 Introduction to Female Longevity 02:06 The Unique Aging Process of Women 03:19 Critical Data Points on Female Longevity 07:08 10 Essential Principles of Female Longevity 07:56 The Critical Decade: 35-45 09:27 The Role of Estrogen in Longevity 11:27 Body Composition Changes in Midlife 12:45 Mitochondria and Female Energy 13:49 Muscle Strength and Longevity 14:55 Cardiovascular Fitness and Lifespan 15:36 Brain Health and Estrogen 16:37 Inflammation and Aging 17:56 Modifying Biological Age 19:42 Conclusion: Designing an Unbreakable Future  

Check Out BioVitalis Peptides: https://biovitalis.org/   Check Out ZONE (Amazing Nootropic for Mental Focus and Energy): https://forjlife.com/products/zone-nootropic-supplement-mental-focus-eye-fatigue   *Disclaimer: This NOT medical advice. Please make sure to seek your own medical professional for medical advice.

In the late 1990s, a strange carbon molecule quietly delivered the single longest lifespan extension ever recorded in mammals. The rats lived about 90% longer, and almost no one was paying attention. This episode breaks down what that molecule is, why it works, and how it may upgrade mitochondria, sleep, and human performance when used correctly. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Chris Burres, founder and chief scientist of MyVitalC and the original long-term manufacturer of carbon 60. Chris has produced this Nobel Prize–winning molecule since the early 1990s, supplying research institutions around the world years before it ever entered the biohacking space. He explains how carbon 60 behaves differently from traditional antioxidants, why stability and concentration used to be major problems, and how modern manufacturing finally made real-world use possible. Chris is also a published author, longevity summit host, patent holder, and longtime science communicator who brings rare clarity and humor to complex biology. Dave and Chris explore how carbon 60 interacts with mitochondria, oxidative stress, metabolism, and electrical signaling in the body, and where it fits alongside ketosis, nootropics, supplements, and functional medicine strategies. They also unpack why improving mitochondrial function often shows up first as better energy and sleep optimization, and how that foundation supports longevity, brain optimization, and Smarter Not Harder performance. Along the way, Dave shares his own early experience with C60, how he uses it today, and why it now shows up even in his Danger Coffee stack. You'll Learn: • Why carbon 60 produced the longest longevity result ever recorded in mammal studies • How mitochondrial efficiency shapes energy, sleep, and human performance • What makes C60 a selective antioxidant instead of a blunt one • Why purity, concentration, and stability determine whether a supplement works • How carbon 60 fits into biohacking stacks built around ketosis and metabolism • What users report first, from focus and resilience to deeper sleep • Why mitochondrial health underpins long-term anti-aging strategies • How to think about supplements through a Smarter Not Harder lens Dave Asprey is a four time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Affiliates: Vibrant Blue Oils | Grab a full-size bottle for over 50% off at https://vibrantblueoils.com/dave. ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: carbon 60 podcast, C60 longevity science, biohacking mitochondria, mitochondrial optimization podcast, anti-aging supplements science, human performance longevity, selective antioxidant mitochondria, sleep optimization biohacking, brain optimization supplements, nootropics longevity stack, ketosis metabolism longevity, functional medicine mitochondria, oxidative stress longevity, carbon 60 supplement science, MyVitalC podcast, Chris Burres interview, Dave Asprey biohacking, Danger Coffee stack, Smarter Not Harder longevity, Nobel Prize molecule longevity, mitochondrial health podcast Resources: • Get a 30% discount on your next purchase of ESS60 at: https://www.myvitalc.com/pages/humanupgradeod?ref=humanupgrade • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 – Introduction & C60 Discovery 4:04 – The Molecule & Nobel Prize 8:27 – Quantum Properties & Superconductivity 11:16 – Rat Longevity Study Results 14:33 – Selective Antioxidant Properties 15:51 – User Experience & Timeline 18:15 – Biological Age Testing 21:33 – Why Oil & Product Development 23:32 – Mechanism of Action 28:13 – Biohacker Discovery Story 30:03 – FDA & Supplement Regulation 33:50 – Migraines & Clinical Observations 37:53 – Athletic Performance 40:43 – Stacking & Contraindications 45:57 – Skincare Product 50:43 – Who Benefits Most 1:00:37 – Mitochondria & Consciousness 1:02:03 – Where to Buy & Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Modern biochemistry and ancient faith are intricately linked in achieving profound healing. Dr. Cowden and Virginia delve into the powerhouse of the cell – mitochondria – exploring how nutrition, supplements, peptides, and understanding your body's unique needs can unlock optimal health, all while considering a holistic, integrative perspective.Where to Find VirginiaWebsiteInstagramFacebookLinkedInDonate

In this episode of Ageless Future, Cade Archibald reframes aging as a bioenergetic problem—not simply “wear and tear” or the passage of time. He explains how mitochondrial dysfunction can quietly precede chronic disease through declining ATP production, rising oxidative stress (ROS), and increasingly inefficient cellular signaling, setting the stage for issues like neurodegeneration, cardiometabolic disease, and autoimmune/inflammatory disorders. Cade highlights how mitochondria act as intelligent signaling hubs that help the body adapt to stress, why symptoms often appear before labs look abnormal, and how restoring energy can unlock repair, detoxification, hormone balance, and immune stability. He closes with practical “mitochondria-charging” strategies—recovery, sleep, heat/cold exposure, red light, and foundational habits—challenging listeners to prioritize restoration to restore health.AGELESS FUTURE:Book Comprehensive Labs: https://agelessfuture.com/longevity-labs/FREE copy of The Peptide Blueprint: https://agelessfuture.com/blueprintSign up for future Health Accelerator Challenges calls LIVE! https://us02web.zoom.us/webinar/register/WN_YZsiUMOzSyqcE8IinC5YEQ#/registrationBooks: https://www.amazon.com/Books-Regan-Archibald/s?rh=n%3A283155%2Cp_27%3ARegan%2BArchibaldArticles: https://medium.com/search?q=Regan+ArchibaldLIKE/FOLLOW/SUBSCRIBE AGELESS FUTURE:YouTube -https://www.youtube.com/@ReganArchibald / https://www.youtube.com/@Ageless.FutureLinkedIn: https://www.linkedin.com/in/regan-archibald-ab70b813Instagram: https://www.instagram.com/ageless.future/Facebook: https://www.facebook.com/AgelessFutureHealth/DISCLAIMER: This video is for educational purposes only and does not provide medical advice, diagnosis, or treatment.  Many of the molecules discussed in this video are research compounds and are not approved by the U.S. Food and Drug Administration (FDA) for any specific medical use, indication, or condition. They are mentioned only in the context of existing scientific literature and ongoing research and are not being recommended, prescribed, sold, or offered through this video.  This content does not endorse or recommend any specific tests, products, procedures, or treatment protocols.References to our clinic are for general educational context only; investigational or non‑approved products are not available for direct ordering or prescribing based solely on viewing this content.  Do not start, stop, or change any medication, peptide, or supplement based on this video. All medical decisions must be made with a licensed prescribing clinician after a proper evaluation. No provider–patient relationship is created by viewing this content or contacting our clinic.  Regan Archibald is a Licensed Acupuncturist and longevity coach. He is not a medical doctor. Cade Archibald is COO and Co-Founder of Ageless Future, also not a medical doctor. All medical decisions, lab ordering, and prescribing in our clinic are performed only by our licensed medical team (MD, APRN, PA).  Viewers should follow the guidance of their own licensed clinicians and local health authorities regarding diagnosis and treatment decisions.

Dr. Jones dives into the world of MOTS-C, explaining its potential to enhance metabolic health. He highlights its role in peptide therapy to optimize healing and promote fat loss. This biohacking approach could be a key to longevity science and overall health.CHAPTERS00:00 What MOTS-c Is & Why It's Unique00:37 How MOTS-c Works in the Cell01:12 Mitochondrial Benefits & Energy Support02:18 Key Benefits: Energy, Metabolism & Fat Loss03:33 MOTS-c for Longevity & Anti-Aging Pathways04:37 Performance, Recovery & Endurance Support05:08 Cognitive Support & Stress Resilience05:38 Why MOTS-c Is Popular in Longevity Protocols06:19 Clinical Uses: Fat Loss, Fatigue & Insulin Resistance06:36 How to Use MOTS-c Safely (Cycling & Dosing Principles)Connect with Dr. Greg JonesInstagram: @doctorjones_doctorjones Enovative Wellness Center: https://enovativewellness.com/

In this episode, Dr. David Jockers reveals the dangers of processed seed oils and how they poison your mitochondria, preventing your body from burning fat efficiently. You'll learn how these oils contribute to chronic inflammation and oxidative stress, making fat burning nearly impossible. Dr. Jockers also explains the harmful effects of processed sugars and starches, which spike insulin levels and keep your body in sugar-burning mode. By reducing these ingredients, you can kickstart fat burning and improve overall metabolic health. The episode dives into the harmful chemicals found in many everyday foods, including preservatives and artificial sweeteners. Dr. Jockers discusses how these chemicals disrupt your cell function and damage your gut, making it essential to avoid them for optimal health and fat loss. In This Episode:  00:00 Introduction to Mitochondria and Seed Oils 00:21 Podcast Introduction and Overview 03:27 Three Food Ingredients to Avoid 03:52 Processed Seed Oils: The Hidden Danger 07:33 Processed Carbohydrates and Their Impact 09:34 Harmful Chemicals in Food 11:19 Healthy Alternatives and Recommendations 15:20 Nutrient-Rich Foods for Better Health 20:47 Hydration and Gratitude 22:41 Conclusion and Final Thoughts   Boost your health with Paleo Valley's Organic SuperGreens powder. Packed with 23 nutrient-rich superfoods, it's free from inflammatory cereal grasses and easy to add to any drink or recipe. It's USDA organic, gluten-free, and contains no fillers or sugars. Enhance your daily nutrition with a quick scoop! Save 15% at Paleo Valley using code 'JOCKERS'   When it comes to cooking, Chef Foundry offers the perfect solution with their P 600 ceramic cookware, which is free from Teflon, PFAS, and plastic coatings. Made with Swiss-engineered ceramic, this cookware makes it easy to prepare healthy meals without the toxins. Take 20% off with code SAFE20 at chefsfoundry.com/jockers and upgrade your kitchen today.   Get Huel's full High-Protein Starter Kit with my exclusive offer of 20% OFF online with my code Jockers20 at huel.com/Jockers20. New Customers Only. Code only valid for the bundle. Thank you to Huel for partnering and supporting our show!    "Seed oils are poison to your mitochondria—destroying your ability to burn fat and causing chronic inflammation"  ~ Dr. Jockers     Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio     Resources: Paleovalley Save 15% using JOCKERS at paleovalley.com/jockers. Visit chefsfoundry.com/jockers for 20% off with code SAFE20. Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/   If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/ 

Your butt is not about aesthetics. It is a longevity organ that directly impacts metabolism, brain optimization, resilience, and how long you stay strong as you age. In this episode, you'll learn why strength training and protein intake matter more than body fat percentage, how mitochondria drive human performance and recovery, and why building muscle protects your brain, stabilizes mood, and supports long-term longevity. This conversation reframes biohacking, anti-aging, and health from weight loss to muscle span, the length of time you live with strong, functional skeletal muscle. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Gabrielle Lyon, an accomplished physician and New York Times bestselling author of Forever Strong: A New, Science-Based Strategy for Aging Well, and author of the upcoming The Forever Strong Playbook, releasing January 27, 2026. Dr. Lyon pioneered the Muscle-Centric Medicine® approach, which places muscle at the center of disease prevention, metabolic health, and true vitality. She has trained elite athletes, military operatives, and public figures, while also living this philosophy at home as a mother of two with her husband, a retired Navy SEAL. Together, they break down why intermuscular fat may matter more than body fat percentage, how skeletal muscle drives insulin sensitivity and lowers inflammation, and why becoming physically stronger improves brain function and neuroplasticity. They explore protein needs across the lifespan, fasting, ketosis, carnivore-style nutrition, supplements, sleep optimization, and the real tradeoffs of GLP-1 drugs, including the risk of accelerated muscle loss if strength and protein are neglected. The conversation also covers mindset, hormesis, and why physical resilience creates emotional regulation and clearer decision-making in a world increasingly shaped by AI and convenience. This episode is essential listening for anyone serious about biohacking, hacking human performance, longevity, mitochondria, neuroplasticity, nootropics, metabolism, functional medicine, anti-aging strategies, supplements, and living Smarter Not Harder, ideally with a cup of Danger Coffee in hand. You'll Learn: • Why your glutes and skeletal muscle are critical drivers of longevity and brain health • Why intermuscular fat can matter more than body fat percentage for metabolic dysfunction • How strength training improves neuroplasticity, cognition, and emotional resilience • Why protein needs increase with age and why outdated limits can hold you back • What GLP-1 drugs get right, where they fail, and how to protect muscle span • Why progressive stimulus beats lifting heavy for long-term strength and injury prevention • How sleep optimization and recovery support mitochondria and human performance • How building muscle creates clarity, resilience, and better decision-making Dave Asprey is a four time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Thank you to our sponsors! Quantum Upgrade | Support your brain, energy, focus, sleep, and recovery with Quantum Upgrade, a 24/7 streaming quantum energy service designed to work continuously in the background. Try it free for 15 days with no credit card required: https://quantumupgrade.io/DAVE Screenfit | Get your at-home eye training program for 40% off using code DAVE at https://www.screenfit.com/dave BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle. KillSwitch | If you're ready for the best sleep of your life, order now at https://www.switchsupplements.com and use code DAVE for 20% off. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: muscle longevity organ, glutes brain health, strength training longevity podcast, muscle span aging, intermuscular fat metabolism, IMAT insulin resistance, skeletal muscle brain function, neuroplasticity strength training, protein intake aging, high protein diet longevity, metabolism muscle health, mitochondria muscle brain, muscle centric medicine podcast, gabrielle lyon podcast, forever strong playbook, women strength training longevity, GLP-1 muscle loss, sarcopenia aging prevention, resistance training brain health, sleep optimization muscle recovery, fasting ketosis muscle health, carnivore diet muscle metabolism, functional medicine muscle health, biohacking strength longevity, human performance muscle, anti-aging strength training, supplements muscle recovery, progressive stimulus training, blood flow restriction training, muscle resilience mindset Resources: • Get Gabrielle's NEW book Forever Strong: https://drgabriellelyon.com/forever-strong/ • Gabrielle's Website: https://drgabriellelyon.com/ • Follow Gabrielle's Instagram: https://www.instagram.com/drgabriellelyon/ • Gabrielles Youtube: https://www.youtube.com/@DrGabrielleLyon • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 – Introduction 1:01 – The Playbook vs Workbook 3:47 – Protein & Metabolic Health 6:21 – Mindset & Negativity 7:20 – Histamines & Hot Flashes 10:49 – Women & Strength Training 13:40 – Connective Tissue & EDS 16:15 – Muscle Span & Aging 19:41 – Training for Kids 21:55 – Pain Cave & Discomfort 25:25 – Emotional Regulation 29:46 – Resilience & Dating 32:11 – Building Friction & Discernment 35:47 – Self-Denial vs Awareness 41:03 – Mitochondria & Energy 42:46 – Bigger Booty, Bigger Brain 44:52 – Body Fat vs IMAT 49:01 – Measuring Muscle Health 52:08 – GLP-1s & Muscle Loss 56:12 – Protein Absorption Myths 59:30 – mTOR & Protein 1:01:29 – Closing Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Peter Cowan and I discuss the surge in non-contact soft-tissue injuries of 49ers players and possible mechanisms including chronic magnetic field exposure from nearby electrical substation, circadian rhythm disruption causing mitochondrial dysfunction, impaired collagen repair and delayed healing.Peter Cowan is a software developer, health coach with an interest in applied circadian biology and EMF mitigating consultant. PODCAST SPONSORS

In this episode of the Soil Sisters Podcast, meet Dr. Ben Edwards, founder and CEO of Veritas Medical and Veritas Wellness in Lubbock, Texas. Dr. Edwards shares his path from conventional family medicine to a holistic, root-cause resolution approach to health and wellness. He discusses his transformation following a divine intervention that guided him to realize the flaws in conventional chronic disease management. The conversation explores real patient experiences and the importance of nutrition, hydration, movement, and peace—The four pillars taught at Veritas Wellness. Dr. Ben also explains in practical terms the role of the gut microbiome and mitochondrial health in foundational wellbeing. You'll gain insights into the power of mindset, the significant impact of epigenetics, and the interconnectedness of soil health and human health. Tune in to learn how you're the cure you've been looking for.MEET OUR GUEST: Dr. Ben Edwards has over 20+ years in the medical field. He is the founder and CEO of Veritas Medical and Veritas Wellness in Lubbock, TX. And he also hosts the "You're The Cure" Podcast (Top 75 Functional Health Podcast), where he educates people on getting to the root cause of disease, and teaching them how to NOT NEED a Doctor!Raised in Belton, TX, Dr. Edwards holds degrees from Baylor University and the University of Texas Medical School at Houston. He completed his residency at Waco's McLennan County Medical Education and Research Foundation before moving to West Texas in 2005 with his wife Jamie where Dr. Edwards was the only doctor in the county at the Garza County Health Clinic. After 7 years of practicing conventional medicine, a divine appointment opened his eyes to root cause resolution medicine.TIME STAMPS:00:00 Welcome to the Soil Sisters Podcast00:43 Introducing Dr. Ben Edwards00:52 Dr. Ben's Medical Journey04:17 A Divine Appointment  08:39 Challenging Conventional Medicine09:18 A Nurse Practitioner's Transformation14:39 The Power of Alternative Medicine27:10 Personal Testimonies and Success Stories31:01 Integrative Approaches to Cancer Treatment33:23 Transitioning to Root Cause Resolution37:14 A New Beginning: Starting Veritas Medical38:59 Overcoming Challenges: Building the Practice40:41 The Insurance Dilemma: Breaking Free from The System41:34 The Power of Mitochondria and Microbiome42:47 Launching Veritas Wellness: Health Coaching Revolution44:25 The Four Pillars of Wellness59:54 Epigenetics: Taking Control of Your Health01:09:43 Healthy Soil, Healthy Gut01:12:48 Conclusion: Empowering Health and Wellness

In the third installment of the Skin Anarchy and Timeline Masterclass, Dr. Ekta Yadav sits down with Dr. Brad Currier, Manager of Clinical Trials at Timeline, for a behind-the-scenes look at what real evidence in longevity science and skincare actually requires.With a foundation in muscle physiology, exercise science, and aging research, Dr. Currier brings a performance-driven lens to longevity — reframing skin not as a cosmetic surface, but as a mitochondria-dense longevity organ, biologically linked to muscle health, metabolic resilience, and cellular energy. The episode explores why mitochondrial function may be one of the most underappreciated drivers of how both skin and the body age.At the center of the conversation is Timeline's research on urolithin A, a postbiotic shown to support mitochondrial renewal. Rather than relying on marketing narratives, Timeline has built its platform on mechanism-first science, translating years of cellular research into human clinical trials — including biopsy-based studies that reveal measurable changes in collagen synthesis and skin structure.Dr. Currier also pulls back the curtain on the truth about clinical claims in beauty — explaining why many “clinically tested” labels lack rigor, how underpowered or biased studies distort results, and what separates meaningful, published human data from perception-based marketing. From wrinkle depth to hydration to barrier function, he outlines how Timeline measures outcomes that reflect real biological change — not just surface-level improvement.The episode ultimately reframes longevity as precision science, not hype — emphasizing the importance of human trials, mitochondrial health, and transparent evidence in an industry flooded with buzzwords.Listen to the full episode of Skin Anarchy to hear Dr. Brad Currier unpack what clinical validation should look like — and why the future of longevity skincare depends on measurable biology, not marketing promises.SHOP TIMELINEDon't forget to subscribe to Skin Anarchy on Apple Podcasts, Spotify, or your preferred platform.Reach out to us through email with any questions.Sign up for our newsletter!Shop all our episodes and products mentioned through our ShopMy Shelf!Support the show

Today I'm joined by neuroscientist and mitochondrial health expert Siobhan Mitchell to cut through the noise around mitochondria, inflammation, NAD, and what actually matters for energy, recovery, and brain health in midlife We unpack why mitochondria are not just “battery packs”, they are a master regulator of oxidative stress, immune signalling, and cellular aging. Siobhan explains the difference between hormetic stress that upgrades your system (like training) versus chronic stress that drains it WHAT YOU'LL LEARN: • What mitochondria actually do, beyond “energy production”  • Mitophagy and mitochondrial biogenesis, and why both decline with age  • The difference between hormetic stress (exercise) and chronic stress (modern life)  • Why mitochondrial dysfunction can drive inflammation and immune overactivation  • How brain energy demand and oestrogen loss intersect in menopause symptoms  • CD38, inflammation, and why staying lean matters for NAD preservation  • Why NAD precursors can be wasted, and what supports conversion inside the cell  • The practical take on timing, training, and recovery support TIMESTAMPS 00:01 Mitochondria, ATP, and the oxidative stress trade-off  04:14 Mitophagy, mitochondrial biogenesis, and aging  16:13 Mitochondria as immune regulators, inflammation and cytokines  23:09 Brain energy, menopause, oestrogen, and cognitive decline mechanisms  29:33 NAD explained, CD38, and why NAD drops with age  48:56 NAD, GLUT4, insulin sensitivity, and perimenopause metabolism  53:19 Where to learn more, discount code, and closing VALUABLE RESOURCES ⁠Join The High Performance Health Community⁠ ⁠Click here⁠ for discounts on all the products I personally use and recommend A BIG thank you to our sponsors who make the show possible Get 10% off MitoQ NAD+ - www.mitoq.com with code ANGELA Get 35% off Timeline Mitopure by visiting this link while the offer lasts - https://www.timeline.com/promotions/angela35 Upgrade your cellular health - get 20% off Beam Minerals at http://beamminerals.com/ANGELA & use code ANGELA at checkout ABOUT THE GUEST Dr Siobhan Mitchell - Chief Scientific Officer - MitoQ Siobhan is the Chief Scientific Officer at MitoQ. She completed her PhD at SUNY Albany and a post-doctoral fellowship in brain ageing at the University of Washington. Siobhan has held roles at the three largest food companies in the world (Unilever, Nestlé, and PepsiCo), where she conducted trials in Europe, North America, and Asia, investigating the effects of nutrition on cognitive decline, mood, and performance. Additionally, she was Senior Director of Research at Noom, where she led a team investigating the behavioural and health effects of weight loss and mental health ABOUT THE HOST Angela Foster is an award winning Nutritionist, Health & Performance Coach, Speaker and Host of the High Performance Health podcast. A former Corporate lawyer turned industry leader in biohacking and health optimisation for women, Angela has been featured in various media including Huff Post, Runners world, The Health Optimisation Summit, BrainTap, The Women's Biohacking Conference, Livestrong & Natural Health Magazine. Angela is the creator of BioSyncing®️ a blueprint for ambitious entrepreneurial women to biohack their health so they can 10X how they show up .without burning out. CONTACT DETAILS ⁠Instagram⁠ ⁠Facebook⁠ ⁠LinkedIn⁠ Disclaimer: The High Performance Health Podcast is for general information purposes only and do not constitute the practice of professional or coaching advice and no client relationship is formed. The use of information on this podcast, or materials linked from this podcast is at the user's own risk. The content of this podcast is not intended to be a substitute for medical or other professional advice, diagnosis, or treatment. Users should seek the assistance of their medical doctor or other health care professional for before taking any steps to implement any of the items discussed in this podcast.

In this episode, we're joined by Dr. Darren Schmidt, a chiropractor who has dedicated his practice exclusively to clinical nutrition and nutritional healing. He is the founder of the Nutritional Healing Center of Ann Arbor and a nationally recognized speaker on chronic illness and metabolic health. Dr. Schmidt's nontraditional path into healthcare stems from his rejection of conventional medical models that have failed. Drawing from over 30 years of clinical experience, he explains why many people never fully recover from chronic illness — and how addressing cellular function, toxin overload, and nutritional deficiencies can change that… We also dive into his 2024 book, Optimal Health: The 7 Step System to Transforming Your Health with Nutritional Healing, where he outlines the fundamental causes of chronic disease, including the often-misunderstood difference between detoxification and drainage. Dr. Schmidt breaks down how issues like mold exposure, parasites, mitochondrial dysfunction, and metabolic stress quietly undermine health. This discussion covers: What separates Dr. Schmidt from other doctors. How diet and supplements help people get well. The unique mechanisms of chronic illness. The 7-step framework from Optimal Health Follow Dr. Schmidt on social media: YouTube • TikTok • Instagram • Facebook

Why do so many people struggle with fatigue, stubborn weight gain, hormone issues, and burnout — even when they're eating “clean” and training hard? In this episode, we break down the real reason your body isn't healing and why most health advice fails to address the root cause.Joined by Lindsay Perry, this conversation dives deep into a systems-based approach to health, exploring how the gut, liver, hormones, nervous system, sleep, and stress all work together to control energy, metabolism, and long-term results.Rather than focusing on symptoms, trends, or extreme diets, this episode explains what's happening under the hood — from ATP production and mitochondrial function to cortisol regulation, nervous system balance, and metabolic flexibility. You'll learn why pushing harder often backfires and how chronic stress quietly sabotages recovery, fat loss, and hormone health.We cover:Why gut and liver health are foundational for hormones and energyHow stress and nervous system dysregulation block healing and fat lossThe role of sleep and circadian rhythm in metabolism and recoveryWhy detoxification and elimination are biological processes — not fadsHow to fuel properly based on stress, activity, and current health stateLindsay Perry brings real-world coaching insight throughout the episode, helping connect science with practical application for people who feel stuck despite doing “everything right.”If you're tired of surface-level health advice and want a clear, root-cause explanation of how the body actually heals, this episode will change how you think about health, fitness, and recovery.00:00 – Introduction & Why Most People Aren't Healing00:41 – The “March Method” & Root-Cause Health Explained01:02 – ATP, Mitochondria & Cellular Energy Basics01:19 – Hormones, Cycles & Why Balance Matters02:44 – Detox, Elimination & Why the Body Gets Stuck04:14 – Cold Exposure, Stress Adaptation & Recovery05:50 – Stress Load, Burnout & Early Cortisol Discussion07:55 – Fueling the Body: Fat vs Carbs Explained10:57 – Sleep, Circadian Rhythm & Metabolic Health12:12 – Gut Health: The Foundation of Healing15:48 – Liver Function, Detox Pathways & Hormones18:35 – Inflammation, Energy Deficits & Fatigue21:30 – Nervous System Regulation & Chronic Stress24:35 – Cortisol, Survival Mode & Weight Loss Resistance28:10 – Why Pushing Harder Makes Things Worse32:24 – Metabolic Flexibility & Long-Term Healing34:27 – Nervous System Reset & Final Takeaways35:57 – Closing ThoughtsDisclaimer:The information discussed in this episode is for educational and informational purposes only and is not intended as medical advice. This content is not a substitute for professional medical diagnosis, treatment, or guidance. Always consult with a qualified healthcare provider before making changes to your diet, lifestyle, supplements, or health practices.

Today, I'm joined by the incredible Anthony Castore, a trailblazer who fuses elite strength coaching with deep cellular medicine. In our conversation, Anthony shares his journey from a young athlete determined to defy genetic odds to becoming an expert in both physical training and the nuanced science of peptides, mitochondria, and bioregulators.   Use code NAT10 for 10% off products at https://alchemiqlabs.com/   Episode Timestamps: Welcome and episode introduction ... 00:00:00 Anthony Castore's path from strength coaching to cellular medicine ... 00:05:55 Connecting strength training with cellular pathways (AMPK, mTOR) ... 00:12:27 Explaining and balancing AMPK and mTOR for performance ... 00:13:03 Training strategies: Metabolic, hypertrophy, and neural approaches ... 00:18:18 Building a solid foundation: Lifestyle, training, nutrition, peptides ... 00:23:04 Assessing recovery capacity and individualizing protocols ... 00:26:02 Mitochondrial fission, fusion, and targeted adaptation ... 00:29:57 Optimizing muscle gain and fat loss through calories and recovery ... 00:31:00 Differentiating bodybuilder vs. longevity approaches ... 00:34:44 Integrating peptides and support molecules into routines ... 00:40:44 Ketone esters and mitochondrial peptide interventions ... 00:41:20 Cautions on stacking and combining interventions ... 00:54:04 Lessons learned from overdoing interventions ... 01:05:02   Our Amazing Sponsors: Vitali - combines pharmaceutical-grade copper peptides with zero-age exosomes to support clearer cellular signaling and long-term skin resilience, working with your biology instead of forcing change. Visit VitaliSkincare.com and use code NAT20 for 20% off.   BEAM Minerals - Low energy often starts in the mitochondria. Support cellular energy with a bioavailable liquid mineral supplement — and get 20% off at beamminerals.com with code NAT20.   Complete Liver Complex by LVLUP Health - supports your liver's natural detox pathways so your body can reset after the holidays without suffering. Go to lvluphealth.com and use code NAT for 20% off.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Full Show Notes: https://bengreenfieldlife.com/lavalle/ In this episode, I sit down with the legendary clinical pharmacist Jim LaValle for a fascinating exploration of some of the most innovative approaches to health, performance, and longevity. We discuss everything from peptides and small molecules for mitochondrial and kidney support to the science behind improving VO2 max, brain function, sleep, and more. Jim LaValle unpacks his decades of experience, shares cutting-edge research on metabolic health, and explains the power of his Metabolic Code test—which I recently tried myself—for identifying and addressing the biggest bottlenecks in your health journey. Throughout our conversation, we swap stories about nutrition missteps (think gallons of dairy and endless antibiotics), dive into the practical application of peptides like KPV, BPC-157, and lorazotide for healing the gut, and examine trends Jim repeatedly sees even in high performers—like stress-driven hormone changes and sneaky signs of inflammation. If you’re curious about how personalized lab testing, wearable data, and smart supplementation can help you feel better, perform better, and age powerfully, you’ll love the insights in this episode. James "Jim" B. LaValle, B.S.Pharm, CCN, MT, DHM, DHPh, is an internationally recognized clinical pharmacist, author, and board-certified clinical nutritionist, with over 40 years of clinical experience in natural products, lifestyle, drug/nutrient depletion, compounding pharmacy, and peptides. Episode Sponsors: Truvaga: Balance your nervous system naturally with Truvaga's vagus nerve stimulator. Visit Truvaga.com/Greenfield and use code GREENFIELD30 to save $30 off any Truvaga device. Calm your mind, focus better, and recover faster in just two minutes. ZBiotics Pre-Alcohol Probiotic: The world's first genetically engineered probiotic that helps break down the toxic byproduct of alcohol, Zbiotics Pre-Alcohol allows you to enjoy your night out and feel great the next day. Order with the confidence of a 100% money-back guarantee and 15% off your first order at zbiotics.com/BEN15. TRIUMPH Coaching: Join me for one-on-one coaching with me and my hand-picked team, custom-built around your labs, your lifestyle, and goals, until you actually hit them. No guesswork. Just results. If you’re finally ready to stop wasting time and money and start living the boundless life you know is possible, go to jointriumphcoaching.com and book your call. Just Thrive: Take the Just Thrive FEEL BETTER challenge today, and save 20% on your first Gut Essentials Bundle. Just Thrive Probiotic is the only probiotic clinically proven to arrive 100% alive in your gut, reducing bloat, better energy, and even clearing skin. Digestive Bitters packs 12 science-backed herbs in one tasteless capsule that jumpstarts your digestion and supports GLP-1 production so cravings don’t control you. Visit justthrivehealth.com/BEN and save 20% with promo code BEN. See the difference for yourself or get a full product refund, no questions asked. Boundless Bar: If you’re ready to fuel workouts, sharpen your focus, and support whole-body vitality, grab your Boundless Bars now at boundlessbar.com —and save 10% when you sign up for a Boundless Bar subscription.See omnystudio.com/listener for privacy information.

This week, we are joined by Chris Masterjohn, PhD. Chris is a nutritional scientist, a former professor, and the founder of Mitome. With a PhD in nutritional science and years of research in mitochondrial biology, Chris's work focuses on translating peer-reviewed science into practical tools for human health. At Mitome, Dr. Masterjohn pioneered the first analysis designed to measure mitochondrial respiratory chain function directly, identifying individual energy bottlenecks and guiding personalized science-backed protocols to optimize the system responsible for over 90% of cellular energy production. His mission is to bring mitochondrial testing out of the rare disease space and into everyday health. In this interview, we discuss why so little is understood about the role serotonin plays in the body and how our mitochondria might play a part in the experince of antidepressant withdrawal. *** Thank you for being with us to listen to the podcast and read our articles this year. MIA is funded entirely by reader donations. If you value MIA, please help us continue to survive and grow. https://www.madinamerica.com/donate/ To find the Mad in America podcast on your preferred podcast player, click here: https://pod.link/1212789850 © Mad in America 2025. Produced by James Moore https://www.jmaudio.org

Your body does not fail all at once. Aging starts when cells quietly shift into survival mode and never come back out. In this episode, you go inside the thinking of a true medical outlier to understand how stress, travel, toxins, and metabolic overload reprogram cells, shut down energy, and accelerate aging, and how restoring mitochondrial function can reverse that trajectory from the inside out. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Theodore Achacoso and Boomer Anderson, leaders in Health Optimization Medicine and Practice. Dr. Achacoso is a physician-scientist and the founding pioneer of Health Optimization Medicine, known for his work on cellular networks, metabolomics, and mitochondrial function. Boomer Anderson is the CEO of Smarter Not Harder and Troscriptions, where he focuses on translating complex biology into practical tools for human performance and longevity. Together, they unpack how cells respond to perceived threats through the Cell Danger Response, why mitochondria control energy, inflammation, and repair, and why chasing disease labels misses the real drivers of aging. The discussion covers methylene blue as an electron recycler, why LDL cholesterol plays a role in detoxification and immune signaling, how fasting and ketosis shift metabolism between repair and growth, and why sleep optimization, circadian rhythm, and light exposure matter even more when you travel. They also explore neuroplasticity, consciousness, nootropics, supplements, and why health optimization works best when you restore balance instead of forcing outcomes. You'll Learn: • What the Cell Danger Response is and how it reshapes aging and performance • How mitochondria sense stress before symptoms appear • Why cellular energy controls resilience, sleep, and longevity • How methylene blue supports mitochondrial electron flow • Why fasting and ketosis shift metabolism between repair and growth • How travel, light, and circadian disruption affect aging • Why very low LDL can impair detoxification and immune signaling • Why real anti-aging starts at the cellular level, not with disease labels Thank you to our sponsors! AquaTru | Go to https://aquatruwater.com/daveasprey and save $100 on all AquaTru water purifiers. Screenfit | Get your at-home eye training program for 40% off using code DAVE at www.screenfit.com/dave. Puori | Use code DAVE at puori.com/DAVE to get 32% off your Puori Fish Oil when you start a subscription. You save more than $18. fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: cell danger response podcast, mitochondria aging, mitochondrial dysfunction aging, health optimization medicine, dr ted achacoso, boomer anderson, troscriptions, troscriptions methylene blue, methylene blue mitochondria, methylene blue biohacking, cellular aging podcast, anti aging mitochondria, metabolic stress aging, fasting ketosis metabolism, mitochondrial energy production, neuroplasticity mitochondria, sleep optimization aging, functional medicine mitochondria, smarter not harder biohacking, dave asprey mitochondria Resources: • Get A Discount On All Troscription Products with code ‘dave' at: https://troscriptions.com/ • Learn More About Methylene Blue From My Full Masterclass Covering The Topic: https://daveasprey.com/mb/ • Discover More About The ‘Health Optimization Medicine and Practice' From Our Guests: https://homehope.org/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 – Trailer 1:25 – Introduction & Guest Background 3:11 – Health Optimization Medicine Origins 4:26 – Root Causes of Health vs Disease 6:15 – Biohacking & Self-Experimentation 8:19 – Medicinal Plants & Nootropics 11:25 – Travel & Jet Lag Solutions 13:42 – Cell Danger Response 17:38 – Metabolites & Cellular Health 18:57 – LDL & Lipopolysaccharides 20:42 – Cellular Model & First Principles 22:55 – Consciousness & Mitochondria 25:46 – Nanotechnology Research 28:55 – Giving Back & Service 31:17 – Blue Cannatine Development 34:48 – Methylene Blue Products 36:22 – Metformin Discussion 38:00 – Dosing & Cordycepin 41:25 – Closing & Discount Code See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dorian Yates is a former professional bodybuilder, six-time Mr. Olympia winner and a pioneer of high-intensity, low-volume training for building muscle size and strength. He explains how anyone can vastly improve their fitness, mindset and appearance by training with weights just two or three days per week for less than an hour. We also discuss how to determine your natural strengths and passions and select which life path is right for you. Dorian also shares his journey and transformation from wayward youth to world champion athlete, his exploration of psychedelics, views on cannabis and on longevity and health optimization more generally. The knowledge and wisdom Dorian shares is valuable to men and women of all ages. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David Protein: https://davidprotein.com/huberman Joovv: https://joovv.com/huberman Our Place: https://fromourplace.com/huberman LMNT: https://drinklmnt.com/huberman Function Health: https://functionhealth.com/huberman Timestamps (00:00:00) Dorian Yates (00:03:17) High-Intensity Training, Bodybuilding, Blood & Guts (00:09:15) Muscular Failure, Stimulate & Recover; Anabolics (00:12:04) Sponsors: David & Joovv (00:14:33) Muscle Pump, Stimulus; Recovery Weeks (00:17:32) Beginners & Learning Correct Mechanics; Diabetes (00:22:13) Research vs Real World, Tool: High-Intensity, Low-Volume Training, HIIT Sprints (00:28:53) Bodybuilding Journey, Reading, Training Logs, Aspiration, Parents (00:39:21) Sponsors: AG1 & Our Place (00:42:46) TRT, Steroids, Genetics, Early Bodybuilding Career; Tool: Steroid Risks (00:53:57) Father & Son Relationship; Training Evolution (00:58:31) Workout Intensity & Motivation, Self-Mastery, Transforming Anger (01:05:34) Death; Opportunity Analysis; Bodybuilders, Steroids & Diuretics (01:12:18) Human Possibility, Fitness & Health Progression, Nutrition (01:16:05) Sponsor: LMNT (01:17:26) Mike Mentzer (01:20:42) 1992-1993 Mr. Olympia, Underdog vs Favorite Mindset (01:30:22) Inspiration & Achieving Goal; Retirement, Transition & Identity (01:38:52) Flexibility, Winning vs Loving the Process (01:43:08) Aging, Exercise & Posture (01:46:34) Sponsor: Function (01:48:22) Losing Muscle & Diet Change; Breathing; Health & Mind (01:52:02) Psychedelics, DMT, Ayahuasca, Perspective & Connection (02:01:20) Risks, Research & Psychedelics; Brain Plasticity, Perspective Change (02:06:23) Sunlight & Mood, Schizophrenia, Dopamine, Mitochondria (02:12:15) Cannabis, Smoking & Health; Cancer; Breathwork (02:19:34) Cannabis & Motivation, Individual Variation, THC Levels (02:25:22) Plant Medicine, Kratom, Natural Plants vs Extracts (02:28:53) Training for Women, Losing Fat & Resistance Training; Resilience (02:33:52) DY Nutrition, Supplements; Life Purpose & Consciousness (02:44:40) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

Video: https://www.youtube.com/watch?v=A6ymQgVLC5cAutism & Parkinson's https://youtu.be/1E53ZYehUCU?si=69pKeFSKi07GGsATHypothyroid Biomarker https://youtu.be/X6CxX9kA6b0?si=Bkr8ZKooNdie-N6IDr. Kristen Lyall, ScD https://youtu.be/cjBR8m82KZQ?si=C-Tclr25oBbid7qGNicole Rincon & links to her other episodes in notes https://youtu.be/jRd7rE38W90?si=i8CvVutA4a1K9NzeDaylight Computer Company, use "autism" for $50 off at https://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount at https://getchroma.co/?ref=autismFig Tree Christian Golf Apparel & Accessories, use "autism" for 10% discount at https://figtreegolf.com/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount at https://thecognity.com00:00 Serotonin Recap: thalamocortical connections (esp. S1 somatosensory)02:41 Aromatic Amino Acids & UV-sensitive aromatic benzene rings04:56 Personal Sunlight Reversal Host reversed Hashimoto's (2005–2024) via increased sunlight07:58 Cell-Level Roles Serotonin drives neurogenesis, migration, dendrites/spines; T3 matures organelles, myelination & cellular energy11:00 Maternal Thyroid Dependency Fetus relies on maternal T3/T4 until ~weeks 16–20; hypothyroidism as easy, modifiable biomarker for autism/Parkinson's13:07 Substantia Nigra & Basal Ganglia Neuromelanin/dopamine loss in substantia nigra links autism & Parkinson's; disrupts basal ganglia go/no-go orchestration15:44 Mitochondria & Melanin Energy Cytochrome c oxidase produces H2O in ETC; melanin + water coupling provides power 18:00 Hypothyroidism Biomarker Call Undisputed, simple-to-check risk factor; urgent prenatal thyroid screening & sunlight exposure needed20:36 Modern Environment Impact Blue light/low sunlight blocks synthesis; upstream fixes (reflexes, thyroid checks, sunlight) offer prevention/recovery potential22:15 Serotonin & T3 Synergy Serotonin architects connections; T3 engineers cell/organelle maturity & myelination; combined deficits cascade into autism/Parkinson's24:00 Substantia Nigra Detail Loss of neuromelanin/dopamine in substantia nigra (mesencephalon) impairs basal ganglia; ties to movement disorders in both conditions25:44 Mitochondria Water Production Cytochrome c oxidase (complex IV) generates H2O; melanin & water 27:58 Final Synthesis & Implications Serotonin + T3 critical for cell development/myelination; maternal hypothyroidism disrupts both autism/Parkinson's riskX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

This week I interviewed Dr. Sam Shay. Dr Shay is a functional medicine expert, speaker, and stand-up comic.  With over 25 years of experience in nutrition science, mind-body medicine, and genetic analysis, Dr. Sam guides others in building personalized health strategies rooted in their unique biology. We discussed functional approaches to hypo/hyperthyroidism along with:- the importance of mitochondrial health- using genetics to guide nutrition- carb tolerance testsand his one tip to get your body back to what it once was!Connect with Dr. Shay:https://drsamshay.com/-------How to Take Simple Steps to Reclaim the Body, Energy, and Strength You Had 10-15 Years Ago Using My Stepladder System:https://www.stepladdersystem.com/FREE Nutrition Cheatsheets:https://brian-getleaneatclean.beehiiv.com/subscribeClick to book a FREE 15 minute consult with Brian:https://calendly.com/bdgryn/15min------------Interested in Upgrading your Mitochondria, Improving Energy and Sleep! Check out Troscriptions: https://bit.ly/4ik5kK5Use Discount Code for 10% OFF: EATCLEAN----Watch Get Lean Eat Clean podcast video episodes on YouTube!YouTube.com/@briangryn3680----B.rad Whey Protein Isolate Superfuel:The Best Protein on The Planet! Available in Two Delicious Flavors: Vanilla Bean and Cocoa BeanUse Coupon Code glec10off for 10% off your order!https://a.co/d/731gssV----My favorite health bars with clean ingredients!https://www.eatprima.com/BRIAN6816310% OFF with this link!

Is mitochondrial decline the hidden blueprint that decides how fast your body ages? Josh Trent welcomes Dr. Brad Currier, PhD, Clinical Scientist, to the Wellness + Wisdom Podcast, episode 793, to unpack how mitochondrial health is passed through generations, why modern environments and sedentary living accelerate aging, how mitophagy and Urolithin A restore cellular energy, why gut health blocks or enables longevity, and how exercise plus targeted supplementation can fundamentally shift mood, vitality, and long term health from the inside out. 30% Off Mitopure (Timeline Nutrition) The first clinically tested Urolithin A supplement Mitopure® is a highly pure form of Urolithin A, a postbiotic clinically shown to energize cells, increase muscle strength, and improve endurance. And this is just the beginning. New studies continuously explore and prove the incredible potential of Urolithin A. Few people can get enough Urolithin A from diet alone. Mitopure unlocks 6X the dose of Urolithin A when compared to dietary sources such as pomegranate juice, without the sugar. Mitochondria, our cellular powerhouses, are constantly renewed to fulfill the vast energy demands of cells. As we age, mitochondrial function declines, starting as early as our 30s. Mitopure stimulates the mitochondrial renewal process to protect cells from age-associated decline. Get Mitopure Today Save 30% with code JOSH at checkout In This Episode, Dr. Brad Currier Uncovers: [01:10] How to Optimize Mitochondrial Health How our mitochondrial DNA is passed from mothers to children. The functions of mitochondria in the human body. How our environment affects our mitochondria. Why UV radiation from the sun damages proteins in our cells. How sedentary lifestyle impact mitochondrial health. Resources: Dr. Brad Currier, PhD Timeline Nutrition - 30% off with code JOSH  [08:35] Intergenerational Mitochondrial Health How mitochondrial health is impacted by multiple generations that came before us. Why we're impacted by seven generations before us, and we impact seven generations after us. The importance of nurturing our mitochondrial health. Resources: It Didn't Start with You by Mark Wolynn [12:55] The Cause of Aging What causes faster aging. How our cells become unhealthy and age. Why our cell turnover slows down as we age. How mitochondria break down and impact our energy levels. Resources: 781 Pedram Shojai | Anti-Aging Cult: Why Trying To Live Forever Devours Your Soul [16:55] The Importance of Urolithin A The role of postbiotics in digestion. Why we need Urolithin A for optimal health. How Urolithin A was discovered. Resources: Outwitting The Devil by Napoleon Hill [20:55] You Need to Fix Your Microbiome Why we have to take supplements to maintain our health. How the microbiome blocks production of Urolithin A. Why most people's gut microbiome is damaged. How our gut microbiome lacks diversity compared. [24:15] Gut-Brain Axis How the gut-brain axis is linked to many diseases. Why mitochondria can impact different systems of the body. The importance of supplementing Urolithin A. Why food cannot help us produce more Urolithin A. How aging affects protein absorption. [29:35] Activate Mitophagy to Stop Aging Why Mitopure is the only clinically proven supplement to activate mitophagy. The three phases of the mitochondria's life cycle. Why removing cellular residue prevents aging. How healthy mitochondria can help us live a better life. Why renewing cellular energy requires consistency. [36:05] Scientific Data Behind Mitochondrial Health How mitochondrial health impacts mood and mental health. Why Timeline Nutrition continues running new clinical studies. How repeated scientific research proves whether something truly works or not. Why they publish all of their studies online. [43:40] The Power of Exercise Why professional athletes have a higher risk of heart attack. How exercise is the best tool for health and longevity. Why combining Mitopure with exercise increases mitochondrial health. How weightlifting helps us create new cells. [50:20] The Fundamentals of Health How Brad takes care of his own health. Why exercise is the most important tool for him. The role of a good diet and sleep in our health. [55:20] Change Is Counter-Intuitive Why change can feel counterintuitive at first. The importance of allowing ourselves to feel uncomfortable. How we can't often know for sure what tools or supplements are best for us. "Poor quality food and pollutants in our environment ultimately converge on the mitochondria and have an impact on its ability to produce energy. When we have this accumulation of debris in our cells, they don't work as well and they start releasing toxins that impact cells around them. " — Dr. Brad Currier, PhD Leave Wellness + Wisdom a Review on Apple Podcasts All Resources From This Episode Dr. Brad Currier, PhD Timeline Nutrition - 30% off with code JOSH  It Didn't Start with You by Mark Wolynn 781 Pedram Shojai | Anti-Aging Cult: Why Trying To Live Forever Devours Your Soul Outwitting The Devil by Napoleon Hill Josh's Trusted Products | Up To 40% Off Shop All Products Biohacking⁠ ❤️ WAVwatch - Now 15% off with JOSH100

Are you exhausted all the time? In this solo episode, Darin breaks down why so many people feel chronically exhausted despite eating clean, exercising, and "doing everything right." He explains how modern life disrupts mitochondrial function, circadian rhythm, stress signaling, and nutrient availability, and why fatigue is not a personal failure, but a biological signal. This episode offers a grounded, practical roadmap to restoring energy by realigning your environment, habits, and daily rhythms with how the body is actually designed to function.     What You'll Learn in This Episode: Why chronic fatigue is exploding—even among healthy, active people How mitochondria do far more than "make energy" The role of circadian rhythm, light exposure, and timing in energy production Why stress, overtraining, and modern lifestyles drain cellular energy How emotional suppression and unexpressed stress affect vitality The difference between forcing energy and allowing energy Simple daily practices that support mitochondrial repair How breathwork, stillness, and social connection restore resilience Why nutrition alone isn't enough without rhythm and recovery How to realign your biology with the modern world     Timecodes 00:00:00 – Welcome to SuperLife and the intention behind this episode 00:00:32 – Sponsor: TheraSage and natural frequency-based healing 00:02:10 – Happy New Year + why this conversation matters now 00:02:37 – Are you exhausted even though you're "doing everything right"? 00:03:26 – The modern energy crisis and rising chronic fatigue 00:04:12 – Why surface-level health advice no longer works 00:04:27 – Mitochondria: more than energy factories 00:04:59 – Circadian misalignment, EMFs, and modern stressors 00:05:36 – Overtraining, stress load, and lack of recovery 00:06:00 – Fatigue as a signal, not a lack of discipline 00:06:18 – How artificial light disrupts internal clocks 00:07:25 – Discipline as alignment with natural rhythms 00:07:36 – Emotional release, primal expression, and energy recovery 00:08:47 – Why "why am I tired all the time?" is exploding online 00:09:24 – The mitochondria as environmental sensors 00:10:06 – Stress signaling, thoughts, and cellular energy flow 00:11:18 – Breathwork and slowing the nervous system 00:12:24 – Social connection and low-stress signaling 00:13:02 – Sponsor: Bite toothpaste and eliminating plastic exposure 00:15:19 – Morning sunlight and circadian priming 00:15:52 – Reducing artificial light at night 00:16:15 – Nutrients that support mitochondrial function 00:17:29 – Sleep timing, consistency, and repair 00:18:20 – Evening routines and melatonin protection 00:19:46 – Small daily steps compound into real energy 00:20:17 – Antioxidants, inflammation, and recovery 00:20:49 – Training smarter, not harder 00:21:31 – Breathwork, sauna, and recovery rituals 00:22:26 – Nutrition, protein, and polyphenols 00:24:37 – Five daily energy takeaways 00:25:24 – Energy is permitted, not forced 00:26:03 – Listening to the body and closing reflections 00:26:49 – SuperLife Patreon and community support     Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien     Thank You to Our Sponsors: Therasage: Go to www.therasage.com and use code DARIN at checkout for 15% off Bite Toothpaste: Go to trybite.com/DARIN20 or use code DARIN20 for 20% off your first order.     Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences     Key Takeaway "Fatigue isn't failure. It's feedback. When your environment, timing, and signals align, your biology remembers how to thrive."     Bibliography/Sources: Ames, B. N. (2006). Low micronutrient intake may accelerate the degenerative diseases of aging through allocation triage. Proceedings of the National Academy of Sciences, 103(47), 17589–17594. https://doi.org/10.1073/pnas.0608757103 Bass, J., & Takahashi, J. S. (2010). Circadian integration of metabolism and energetics. Science, 330(6009), 1349–1354. https://doi.org/10.1126/science.1195668 Gooley, J. J., Chamberlain, K., Smith, K. A., Khalsa, S. B., Rajaratnam, S. M., Van Reen, E., Zeitzer, J. M., Czeisler, C. A., & Lockley, S. W. (2011). Exposure to room light before bedtime suppresses melatonin onset and shortens melatonin duration in humans. The Journal of Clinical Endocrinology & Metabolism, 96(3), E463–E472. https://doi.org/10.1210/jc.2010-2098 Kreher, J. B., & Schwartz, J. B. (2012). Overtraining syndrome: A practical guide. Sports Health, 4(2), 128–138. https://doi.org/10.1177/1941738111434406 Meeusen, R., Duclos, M., Foster, C., Fry, A., Gleeson, M., Nieman, D., Raglin, J., Rietjens, G., Steinacker, J., & Urhausen, A. (2013). Prevention, diagnosis, and treatment of the overtraining syndrome: Joint consensus statement of the European College of Sport Science and the American College of Sports Medicine. European Journal of Sport Science, 13(1), 1–24. https://doi.org/10.1080/17461391.2012.730061 Panda, S. (2016). Circadian physiology of metabolism. Cell Metabolism, 23(6), 1152–1163. https://doi.org/10.1016/j.cmet.2016.06.005 Picard, M., Juster, R. P., & McEwen, B. S. (2014). Mitochondrial allostatic load: Putting the 'gluc' back in glucocorticoids. Nature Reviews Endocrinology, 10(5), 303–310. https://doi.org/10.1038/nrendo.2014.22 Picard, M., & McEwen, B. S. (2018). Psychological stress and mitochondria: A systematic review. Psychosomatic Medicine, 80(2), 126–140. https://doi.org/10.1097/PSY.0000000000000544 Picard, M., McElroy, G. S., & Turnbull, D. M. (2015). Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory, and transcriptional responses to acute psychological stress. Proceedings of the National Academy of Sciences, 112(48), 14920–14925. https://doi.org/10.1073/pnas.1518223112 Reiter, R. J., Rosales-Corral, S., Tan, D. X., Acuna-Castroviejo, D., Qin, L., Yang, S. F., & Xu, K. (2017). Melatonin as a mitochondria-targeted antioxidant: One of evolution's best inventions? Journal of Pineal Research, 62(1), e12394. https://doi.org/10.1111/jpi.12394 Scheer, F. A., Hilton, M. F., Mantzoros, C. S., & Shea, S. A. (2009). Adverse metabolic and cardiovascular consequences of circadian misalignment. Proceedings of the National Academy of Sciences, 106(11), 4453–4458. https://doi.org/10.1073/pnas.0808180106 Straub, R. H. (2017). The brain and immune system prompt energy shortage in chronic inflammation and ageing. Nature Reviews Rheumatology, 13(2), 74–79. https://doi.org/10.1038/nrrheum.2016.213 World Health Organization. (n.d.). Micronutrient deficiencies. World Health Organization. https://www.who.int/health-topics/micronutrients

We're back with another episode in a series of highly vetted companies that I love sharing with my community. Today, I'm joined by Forrest Smith, the co-founder and CEO of Kineon. A dynamic entrepreneur with an infectious enthusiasm for his work, Forrest reads and writes fluent Chinese, lives in Mexico, and brings over 20 years of experience building and scaling successful startups. His work at Kineon reflects his optimism and innovative approach in the field of health and wellness technology. In our conversation, we explore what red light therapy (photobiomodulation) is and its cellular and mitochondrial effects. We unpack the benefits of methylene blue, the impact of photobiomodulation on joint pain and thyroid health, and specific contraindications. We also discuss red light therapy and the gut hormone access, peptides, recovery toolkits, and female-centric research related to infertility, PCOS, endometriosis, thyroid health, and more. This is one of those conversations you will likely want to listen to more than once. Be sure to check the show notes for a special offer from Kineon, exclusively for my listeners. IN THIS EPISODE, YOU WILL LEARN: What is red light therapy? How red light therapy supports the body at the cellular level, particularly during the aging process How methylene blue enhances the effects of red light therapy The value of photobiomodulation for treating chronically inflamed joints and muscle tissue How local inflammation in the joints impacts gut health The benefits of red light therapy for female-specific pathologies, such as endometriosis, hypothyroidism, and dysmenorrhea The way that red light therapy works in combination with stem cell treatments, PRP, and extracorporeal shock wave therapy Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow  Cynthia's Menopause Gut Book is on presale now! Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Connect with Forrest Smith Kineon Kineon Labs on Instagram We're giving away TWO Kineon Move+ Pro devices (worth $499 each!) Want to enter? Leave a review of the Everyday Wellness podcast in English on Apple Podcasts or Spotify.  Take a screenshot of your review. Email the screenshot and one reason why you'd like to win to podcast@cynthiathurlow.com (You must live in the U.S. to enter.)

This solo masterclass on oxalates explains why many people who eat clean still struggle with joint pain, kidney stones, fatigue, brain fog, and chronic inflammation. You'll learn how oxalates behave very differently from other plant compounds like lectins, phytates, and salicylates. Unlike those compounds, oxalates physically bind minerals and form microscopic crystals that can lodge in tissues, damage mitochondria, and accumulate over time. This episode will change how you think about superfoods, clean eating, and long term human performance. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey walks you through the real science of oxalates using decades of self experimentation, functional medicine research, and hands on biohacking. As the founder of the biohacking movement, Dave has tested fasting, ketosis, carnivore strategies, supplements, nootropics, sleep optimization protocols, and metabolic interventions to uncover what actually improves resilience, neuroplasticity, and mitochondrial function without unnecessary damage. In this masterclass, you'll learn why oxalates cause problems even when digestion seems fine, why symptoms can show up in joints, kidneys, nerves, skin, and old injuries, and why reducing oxalates too fast can make you feel worse before you feel better. Dave explains oxalate dumping, candida driven oxalate overload, microbiome interactions, and why foods like spinach, almonds, cacao, and green smoothies often backfire over time. He also shares practical ways to lower your oxalate load safely, support mineral balance, and protect your metabolism and brain using a Smarter Not Harder approach. This episode is for you if you eat “healthy” but still feel off, deal with unexplained pain or inflammation, or want to improve longevity, brain optimization, sleep, and human performance without extreme restriction. You'll Learn: • Why oxalates are different from lectins, phytates, and other plant toxins • How oxalates drain minerals and damage mitochondria • What oxalate dumping feels like and how to avoid it • Which superfoods cause the biggest problems and what to replace them with • How hydration, minerals, and supplements affect oxalate clearance • Why oxalates accelerate aging and tissue stiffness over time • Practical biohacking strategies to protect longevity and human performance Thank you to our sponsors! -ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. -Branch Basics | Get 15% off Branch Basics with the code DAVE15 at https://branchbasics.com/DAVE15. -BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 to save 20% off your first order of PerfectAmino. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: oxalates, oxalic acid, biohacking oxalates, oxalate dumping, plant toxins explained, lectins vs oxalates, phytates and mineral absorption, anti-nutrients, superfoods controversy, clean eating problems, kidney stones oxalates, joint pain inflammation, mineral depletion, calcium oxalate crystals, metabolism dysfunction, brain fog causes, neuroplasticity and inflammation, longevity nutrition, anti-aging nutrition, functional medicine oxalates, supplements for oxalates, hydration and kidney health, urinary pH balance, candida and oxalates, microbiome and oxalates, fasting and oxalates, ketosis and oxalates, carnivore diet transition, human performance nutrition, sleep optimization inflammation, nootropics and brain optimization, Dave Asprey oxalates Resources: • Join Our New Low-Oxalate Challenge! https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 – Trailer 1:25 – Introduction 3:18 – What Are Oxalates 5:40 – Oxalates vs Other Plant Toxins 7:18 – Oxalate Sources and Chemistry 9:17 – Kidney Stones and Crystal Formation 10:19 – Oxalate Dumping Explained 12:03 – System Level Effects 14:54 – Inflammation, Mitochondria, and Aging 16:56 – Who Should Pay Attention 19:32 – High Oxalate Foods 24:56 – Smart Food Swaps 27:22 – Exercise and Hydration 29:07 – Clearing Oxalates Safely 31:01 – Summary and Key Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.