Podcasts about mitochondria

Most parents are told ADHD lives only in the brain, but what if the real issue starts much deeper? In this episode, we explore a powerful and often overlooked driver of ADHD symptoms: mineral depletion at the cellular level. You'll hear why calm, focus, sleep, and emotional regulation are literally built from minerals and how many kids are trying to regulate big emotions while running on empty batteries. Dana Kay is joined by Caroline Alan, co-founder of Beam Minerals and author of The Mineral Reset, to break down complex biology into parent-friendly language. Caroline explains how minerals fuel the mitochondria — the tiny "campfires" inside every cell — and why children who lack proper mineral support can appear anxious, wired, exhausted, or stuck in fight-or-flight, even when they eat a "healthy" diet. This conversation helps parents understand why food quality, soil depletion, filtered water, and modern stressors have created a widespread mineral gap — and what gentle, practical steps families can take to support their child's nervous system without overwhelm. If your child struggles with meltdowns, sleep issues, anxiety, or focus, this episode offers a new lens grounded in biology, not behavior. LINKS MENTIONED IN THE SHOW https://beamminerals.com/adhdthrive https://mineralresetbook.com Discount Code: ADHDTHRIVE Connect with Caroline Alan Website: www.carolinealan.com Instagram: https://www.instagram.com/carolinealan.official/ YouTube: https://www.youtube.com/@carolinealan.official KEY TAKEAWAYS [00:00] ADHD symptoms as signs of depletion [03:48] Why minerals matter beyond bones and teeth [08:41] Mitochondria, energy, and brain function [11:05] Low energy cells and nervous system stress [21:10] Soil depletion and food mineral loss [23:31] How filtered water worsens deficiency [30:22] Humic vs. fulvic minerals explained [38:05] Minerals as spark plugs for the brain [44:51] One simple step parents can take today MEMORABLE MOMENTS "Our kids are not being difficult — they're depleted." "Calm is built from minerals." "Minerals are the spark plugs for the brain." "That equals a kid who cannot sit down." "You cannot eat your way out of mineral deficiency." "This isn't ADHD behavior — it's biology." Dana Kay Resources:

We discuss three pivotal studies showing how natural light wavelengths positively influence health from all-cause mortality to visual perfomance to blood glucose control in Type II diabetics.Jonathan Jarecki is a biomedical science sophomore with an interest in light and health, and host of Whole Health Podcast. SUPPORT MY WORK

Dr. Catherine Clinton shares her journey into the growing field of quantum biology that led to her book, Optimize, that explains how light, water, sound and human energy influence the human body at the cellular level, this week on Spirit Gym.Learn more about Catherine's work on her website. Find her on social media via Facebook, Instagram and YouTube.Order Catherine's book, Optimize, and receive more than $400 in free bonuses, including her Quantum Biology Masterclass and her Unlocking Your Quantum Biology course at this link.Timestamps6:51 Catherine's introduction to natural medicine.10:48 Psychoneuroimmunology.19:25 Quantum biology: Waves that hold energy and information.27:21 The electrical capacity of the human body and how pain emerges.34:19 pH balance and a positive charge in the body.48:04 What is the source of electrical currents in nature and humans?57:08 The fascia as a liquid crystalline semiconductor that can create its own charge.1:08:39 When Catherine went all in on quantum biology.1:15:59 Nurturing a relationship with the natural world is one of the most overlooked ways to elevate our health.1:26:17 “We don't end at the barriers of our skin.”1:32:32 Tantra and the Nada Bindu point.1:41:07 The physical receiver.1:47:08 “Use your heart to feel what you know.”1:53:26 Water: The bridge for frequency information.2:03:16 “Awe is medicine.”2:11:04 Digging deeper into the mitochondria.2:27:47 Did you know each of us can communicate with the universe via infrared light transmission?ResourcesWhat is Life? by Erwin SchrodingerWater, The Cradle of Life via its Coherent Quantum Frequencies by Hans Geesink, Dirk Mejier and Igor Jerman (free PDF)Adenosine triphosphate (ATP)Electric Body, Electric Health by Eileen McKusickFind more resources for this episode on our website.Music Credit: Meet Your Heroes (444Hz), Composed, mixed, mastered and produced by Michael RB Schwartz of Brave Bear MusicThanks to our awesome sponsors:PaleovalleyBIOptimizers US and BIOptimizers UK PAUL15Organifi CHEK20Wild PasturesKorrect SPIRITGYMPique LifeCHEK Institute We may earn commissions from qualifying purchases using affiliate links.

Oh hey y'all.I have wanted to have this conversation for a long time, and Dr. Scott Sherr absolutely delivered.We get into what mitochondria actually do, why almost all of us are dealing with some level of dysfunction, and how energy production sits at the center of mental clarity, recovery, stress resilience, and overall health.This is one of those episodes that completely shifts how you think about your body.We also talk about methylene blue, why the internet both loves and fears it, and how to think about nervous system training, oxygen therapy, and health optimization without getting overwhelmed.This one is science heavy but incredibly practical, and honestly, I did not want it to end.Highlights:(03:09) Why mitochondria might be the missing link in modern health(09:08) The real reasons energy production breaks down over time(16:18) What health optimization medicine actually means in practice(20:30) Methylene blue explained without the hype or fear(36:25) Hyperbaric oxygen therapy, when it helps and when it does not(42:05) Building health long term while still feeling better nowConnect with Dr Scott:https://www.linkedin.com/in/drsherr/ https://www.linkedin.com/company/troscriptions/ https://www.linkedin.com/company/onebasehealth/https://www.instagram.com/troscriptions/ https://www.instagram.com/drscottsherr/https://www.instagram.com/onebasehealth/ https://www.instagram.com/homehopeorg/Qualia Mind - click hereCoupon Code: SHOCKANDYALL (15% off any purchase)Visit Nicole's on demand fitness platform for live weekly classes and a recorded library of yoga, strength training, guided audio meditations and mobility (Kinstretch) classes, as well: https://www.sweatandstillness.comGrab Nicole's bestselling children's book and enter your email for A FREE GIFT: https://www.yolkedbook.comFind Nicole on Instagram:https://www.instagram.com/nicolesciacca/Tik Tok: https://www.tiktok.com/@thenicolesciaccaFacebook: https://www.facebook.com/nicolesciaccayoga/Youtube:https://www.youtube.com/channel/UC1X8PPWCQa2werd4unex1eAPractice yoga with Nicole in person in Santa Monica, CA at Aviator Nation Ride. Get the App to book in: https://apps.apple.com/us/app/aviator-nation-ride/id1610561929Book a discovery call or virtual assessment with Nicole here: https://www.calendly.com/nicolesciaccaThis Podcast is proudly produced by Wavemakers Audio

This week I interviewed Santiago Brand. He is an international educator and consultant in brain mapping and neurofeedback, helping professionals, high performers, and everyday individuals use neuroscience to optimize mental health, focus, and resilience.  Santiago combines deep technical expertise with engaging, real-world examples, offering a rare blend of science and practical tools you can use to think more clearly, recover faster from stress, and sustain peak performance in work, sport, and life.Connect with Santiago:https://www.santiagobrand.com/-----------------How to Take Simple Steps to Reclaim the Body, Energy, and Strength You Had 10-15 Years Ago Using My Stepladder System:https://www.stepladdersystem.com/FREE Nutrition Cheatsheets:https://brian-getleaneatclean.beehiiv.com/subscribeClick to book a FREE 15 minute consult with Brian:https://calendly.com/bdgryn/15min------------Interested in Upgrading your Mitochondria, Improving Energy and Sleep! Check out Troscriptions: https://bit.ly/4ik5kK5Use Discount Code for 10% OFF: EATCLEAN----Watch Get Lean Eat Clean podcast video episodes on YouTube!YouTube.com/@briangryn3680----B.rad Whey Protein Isolate Superfuel:The Best Protein on The Planet! Available in Two Delicious Flavors: Vanilla Bean and Cocoa BeanUse Coupon Code glec10off for 10% off your order!https://a.co/d/731gssV----My favorite health bars with clean ingredients!https://www.eatprima.com/BRIAN6816310% OFF with this link!

Mitochondria, Metabolism & Modern Medicine   When "Everything Looks Normal"… But You Don't Feel Normal The Cellular Health Conversation Most People Never Get Why Your Energy, Hormones, and Metabolism Start at the Mitochondria   You can be "doing everything right"… and still feel wiped out by 2 p.m.  You can have "normal" labs… and still feel like something is off.    In this episode of Richer Soul, Rocky sits down with Dr. William Haas to explore what modern medicine often misses: cellular dysfunction, mitochondrial health, gut integrity, hormones, toxins, and recovery tools like hyperbaric oxygen—especially for high performers who hit the wall despite clean living.  "Medical school is teaching how to manage disease. And that was a rude awakening."    5 Soul-Level Insights from Dr. William Haas: (This isn't about chasing more hacks. It's about understanding what your body is telling you.)  Mitochondria aren't just "energy." Dr. Haas explains mitochondria produce ATP (your energy currency) and influence inflammation and immune pathways—so mitochondrial dysfunction can ripple into far more than fatigue.  Some "normal" meds can quietly derail cellular performance. He specifically calls out antibiotics like Cipro and Levoquin as "terrible" for mitochondrial health, notes OTC anti-inflammatories can "uncouple" mitochondria, and discusses metformin potentially impacting mitochondria and contributing to B12 deficiency.  Food sensitivities may be a symptom, not the root cause. When people "light up like a Christmas tree" on food sensitivity testing, Dr. Haas says it often points to gut barrier issues ("leaky gut")—and that fixing the gut can make sensitivities go away.  Hormones don't fail in isolation—stress and sleep shape the outcome. He emphasizes starting with fundamentals like sleep, alcohol reduction, and stress management, and explains "cortisol steal" where high stress drives cortisol production at the expense of testosterone.  Metabolism isn't magic: build lean muscle. When asked how to increase metabolic rate, Dr. Haas gives the simplest (and most effective) answer: build lean muscle mass.    Why This Conversation Matters: Dr. Haas shares that in his 40s—while scaling his medical practice, starting another business helping other doctors, and growing his family—fatigue hit hard, even while he was "doing the right things." It became a wake-up moment that something at a cellular level was off.  That experience pushed him deeper into what he describes as cellular medicine: mitochondria, redox/repair pathways, hormones, toxins, and tools like hyperbaric oxygen.  And it highlights a hard truth for high performers: If your health collapses, your freedom collapses with it.    Money Learning: Dr. Haas also touches a reality most people don't think about: Becoming a doctor can delay earning for a long time. He says he was about 38 when he made his first "real" doctor paycheck—and contrasts that with his brother who started earning right after college.  Rocky adds an important point: sometimes the best decisions happen outside the traditional insurance-driven system—when you can get proactive testing and establish baselines, rather than waiting until the system says you're "sick enough" to qualify.    Key Takeaway: If you want more energy, better recovery, and a longer health span, you can't only focus on symptoms—you have to protect the foundations: mitochondria, gut function, hormones, and lean muscle mass.    Guest Bio: Dr. William Haas: Dr. William Haas is trained in family practice and describes his path into integrative medicine, which he frames as focusing on prevention, food as medicine, the mind-body connection, and pulling tools from different healing modalities. He also mentions training/mentorship with Andrew Weil.  In this episode, he discusses deeper evaluation beyond basic labs, including gut function/microbiome, micronutrients, hormones, inflammation, and toxins such as mycotoxins/mold, microplastics, and heavy metals.    Links: Website: https://vyvewellness.com/ Facebook: https://www.facebook.com/VYVEWellness/ Instagram: https://www.instagram.com/vyvewellness YouTube: https://www.youtube.com/@VYVEWellness Blog: https://vyvewellness.com/blog/   Ready to Go Deeper? Stop accepting "everything looks normal" as the end of the conversation. If you want to identify your own detox, redox, and repair blind spots, start with the free assessment at vyvewellness.com.   #RicherSoul #DrWilliamHaas #Mitochondria #MitochondrialHealth #Metabolism #LeanMuscle #FunctionalMedicine #IntegrativeMedicine #GutHealth #LeakyGut #HormoneHealth #Testosterone #HyperbaricOxygen #HBOT #Longevity #HealthOptimization    Watch the full episode on YouTube: https://www.youtube.com/@richersoul Richer Soul Life Beyond Money. You got rich, now what? Let's talk about your journey to more a purposeful, intentional, amazing life. Where are you going to go and how are you going to get there? Let's figure that out together. At the core is the financial well-being to be able to do what you want, when you want, how you want. It's about personal freedom! Thanks for listening! Show Sponsor: http://profitcomesfirst.com/ Schedule your free no obligation call: https://bookme.name/rockyl/lite/intro-appointment-15-minutes If you like the show please leave a review on iTunes: http://bit.do/richersoul https://www.facebook.com/richersoul http://richersoul.com/ rocky@richersoul.com Some music provided by Junan from Junan Podcast Any financial advice is for educational purposes only and you should consult with an expert for your specific needs.

Check Out BioVitalis Peptides: https://biovitalis.org/   Check Out ZONE (Amazing Nootropic for Mental Focus and Energy): https://forjlife.com/products/zone-nootropic-supplement-mental-focus-eye-fatigue   *Disclaimer: This NOT medical advice. Please make sure to seek your own medical professional for medical advice.

In the late 1990s, a strange carbon molecule quietly delivered the single longest lifespan extension ever recorded in mammals. The rats lived about 90% longer, and almost no one was paying attention. This episode breaks down what that molecule is, why it works, and how it may upgrade mitochondria, sleep, and human performance when used correctly. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Chris Burres, founder and chief scientist of MyVitalC and the original long-term manufacturer of carbon 60. Chris has produced this Nobel Prize–winning molecule since the early 1990s, supplying research institutions around the world years before it ever entered the biohacking space. He explains how carbon 60 behaves differently from traditional antioxidants, why stability and concentration used to be major problems, and how modern manufacturing finally made real-world use possible. Chris is also a published author, longevity summit host, patent holder, and longtime science communicator who brings rare clarity and humor to complex biology. Dave and Chris explore how carbon 60 interacts with mitochondria, oxidative stress, metabolism, and electrical signaling in the body, and where it fits alongside ketosis, nootropics, supplements, and functional medicine strategies. They also unpack why improving mitochondrial function often shows up first as better energy and sleep optimization, and how that foundation supports longevity, brain optimization, and Smarter Not Harder performance. Along the way, Dave shares his own early experience with C60, how he uses it today, and why it now shows up even in his Danger Coffee stack. You'll Learn: • Why carbon 60 produced the longest longevity result ever recorded in mammal studies • How mitochondrial efficiency shapes energy, sleep, and human performance • What makes C60 a selective antioxidant instead of a blunt one • Why purity, concentration, and stability determine whether a supplement works • How carbon 60 fits into biohacking stacks built around ketosis and metabolism • What users report first, from focus and resilience to deeper sleep • Why mitochondrial health underpins long-term anti-aging strategies • How to think about supplements through a Smarter Not Harder lens Dave Asprey is a four time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Affiliates: Vibrant Blue Oils | Grab a full-size bottle for over 50% off at https://vibrantblueoils.com/dave. ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: carbon 60 podcast, C60 longevity science, biohacking mitochondria, mitochondrial optimization podcast, anti-aging supplements science, human performance longevity, selective antioxidant mitochondria, sleep optimization biohacking, brain optimization supplements, nootropics longevity stack, ketosis metabolism longevity, functional medicine mitochondria, oxidative stress longevity, carbon 60 supplement science, MyVitalC podcast, Chris Burres interview, Dave Asprey biohacking, Danger Coffee stack, Smarter Not Harder longevity, Nobel Prize molecule longevity, mitochondrial health podcast Resources: • Get a 30% discount on your next purchase of ESS60 at: https://www.myvitalc.com/pages/humanupgradeod?ref=humanupgrade • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 – Introduction & C60 Discovery 4:04 – The Molecule & Nobel Prize 8:27 – Quantum Properties & Superconductivity 11:16 – Rat Longevity Study Results 14:33 – Selective Antioxidant Properties 15:51 – User Experience & Timeline 18:15 – Biological Age Testing 21:33 – Why Oil & Product Development 23:32 – Mechanism of Action 28:13 – Biohacker Discovery Story 30:03 – FDA & Supplement Regulation 33:50 – Migraines & Clinical Observations 37:53 – Athletic Performance 40:43 – Stacking & Contraindications 45:57 – Skincare Product 50:43 – Who Benefits Most 1:00:37 – Mitochondria & Consciousness 1:02:03 – Where to Buy & Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of Ageless Future, Cade Archibald reframes aging as a bioenergetic problem—not simply “wear and tear” or the passage of time. He explains how mitochondrial dysfunction can quietly precede chronic disease through declining ATP production, rising oxidative stress (ROS), and increasingly inefficient cellular signaling, setting the stage for issues like neurodegeneration, cardiometabolic disease, and autoimmune/inflammatory disorders. Cade highlights how mitochondria act as intelligent signaling hubs that help the body adapt to stress, why symptoms often appear before labs look abnormal, and how restoring energy can unlock repair, detoxification, hormone balance, and immune stability. He closes with practical “mitochondria-charging” strategies—recovery, sleep, heat/cold exposure, red light, and foundational habits—challenging listeners to prioritize restoration to restore health.AGELESS FUTURE:Book Comprehensive Labs: https://agelessfuture.com/longevity-labs/FREE copy of The Peptide Blueprint: https://agelessfuture.com/blueprintSign up for future Health Accelerator Challenges calls LIVE! https://us02web.zoom.us/webinar/register/WN_YZsiUMOzSyqcE8IinC5YEQ#/registrationBooks: https://www.amazon.com/Books-Regan-Archibald/s?rh=n%3A283155%2Cp_27%3ARegan%2BArchibaldArticles: https://medium.com/search?q=Regan+ArchibaldLIKE/FOLLOW/SUBSCRIBE AGELESS FUTURE:YouTube -https://www.youtube.com/@ReganArchibald / https://www.youtube.com/@Ageless.FutureLinkedIn: https://www.linkedin.com/in/regan-archibald-ab70b813Instagram: https://www.instagram.com/ageless.future/Facebook: https://www.facebook.com/AgelessFutureHealth/DISCLAIMER: This video is for educational purposes only and does not provide medical advice, diagnosis, or treatment.  Many of the molecules discussed in this video are research compounds and are not approved by the U.S. Food and Drug Administration (FDA) for any specific medical use, indication, or condition. They are mentioned only in the context of existing scientific literature and ongoing research and are not being recommended, prescribed, sold, or offered through this video.  This content does not endorse or recommend any specific tests, products, procedures, or treatment protocols.References to our clinic are for general educational context only; investigational or non‑approved products are not available for direct ordering or prescribing based solely on viewing this content.  Do not start, stop, or change any medication, peptide, or supplement based on this video. All medical decisions must be made with a licensed prescribing clinician after a proper evaluation. No provider–patient relationship is created by viewing this content or contacting our clinic.  Regan Archibald is a Licensed Acupuncturist and longevity coach. He is not a medical doctor. Cade Archibald is COO and Co-Founder of Ageless Future, also not a medical doctor. All medical decisions, lab ordering, and prescribing in our clinic are performed only by our licensed medical team (MD, APRN, PA).  Viewers should follow the guidance of their own licensed clinicians and local health authorities regarding diagnosis and treatment decisions.

In this episode, Dr. David Jockers reveals the dangers of processed seed oils and how they poison your mitochondria, preventing your body from burning fat efficiently. You'll learn how these oils contribute to chronic inflammation and oxidative stress, making fat burning nearly impossible. Dr. Jockers also explains the harmful effects of processed sugars and starches, which spike insulin levels and keep your body in sugar-burning mode. By reducing these ingredients, you can kickstart fat burning and improve overall metabolic health. The episode dives into the harmful chemicals found in many everyday foods, including preservatives and artificial sweeteners. Dr. Jockers discusses how these chemicals disrupt your cell function and damage your gut, making it essential to avoid them for optimal health and fat loss. In This Episode:  00:00 Introduction to Mitochondria and Seed Oils 00:21 Podcast Introduction and Overview 03:27 Three Food Ingredients to Avoid 03:52 Processed Seed Oils: The Hidden Danger 07:33 Processed Carbohydrates and Their Impact 09:34 Harmful Chemicals in Food 11:19 Healthy Alternatives and Recommendations 15:20 Nutrient-Rich Foods for Better Health 20:47 Hydration and Gratitude 22:41 Conclusion and Final Thoughts   Boost your health with Paleo Valley's Organic SuperGreens powder. Packed with 23 nutrient-rich superfoods, it's free from inflammatory cereal grasses and easy to add to any drink or recipe. It's USDA organic, gluten-free, and contains no fillers or sugars. Enhance your daily nutrition with a quick scoop! Save 15% at Paleo Valley using code 'JOCKERS'   When it comes to cooking, Chef Foundry offers the perfect solution with their P 600 ceramic cookware, which is free from Teflon, PFAS, and plastic coatings. Made with Swiss-engineered ceramic, this cookware makes it easy to prepare healthy meals without the toxins. Take 20% off with code SAFE20 at chefsfoundry.com/jockers and upgrade your kitchen today.   Get Huel's full High-Protein Starter Kit with my exclusive offer of 20% OFF online with my code Jockers20 at huel.com/Jockers20. New Customers Only. Code only valid for the bundle. Thank you to Huel for partnering and supporting our show!    "Seed oils are poison to your mitochondria—destroying your ability to burn fat and causing chronic inflammation"  ~ Dr. Jockers     Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio     Resources: Paleovalley Save 15% using JOCKERS at paleovalley.com/jockers. Visit chefsfoundry.com/jockers for 20% off with code SAFE20. Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/   If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/ 

Your butt is not about aesthetics. It is a longevity organ that directly impacts metabolism, brain optimization, resilience, and how long you stay strong as you age. In this episode, you'll learn why strength training and protein intake matter more than body fat percentage, how mitochondria drive human performance and recovery, and why building muscle protects your brain, stabilizes mood, and supports long-term longevity. This conversation reframes biohacking, anti-aging, and health from weight loss to muscle span, the length of time you live with strong, functional skeletal muscle. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Gabrielle Lyon, an accomplished physician and New York Times bestselling author of Forever Strong: A New, Science-Based Strategy for Aging Well, and author of the upcoming The Forever Strong Playbook, releasing January 27, 2026. Dr. Lyon pioneered the Muscle-Centric Medicine® approach, which places muscle at the center of disease prevention, metabolic health, and true vitality. She has trained elite athletes, military operatives, and public figures, while also living this philosophy at home as a mother of two with her husband, a retired Navy SEAL. Together, they break down why intermuscular fat may matter more than body fat percentage, how skeletal muscle drives insulin sensitivity and lowers inflammation, and why becoming physically stronger improves brain function and neuroplasticity. They explore protein needs across the lifespan, fasting, ketosis, carnivore-style nutrition, supplements, sleep optimization, and the real tradeoffs of GLP-1 drugs, including the risk of accelerated muscle loss if strength and protein are neglected. The conversation also covers mindset, hormesis, and why physical resilience creates emotional regulation and clearer decision-making in a world increasingly shaped by AI and convenience. This episode is essential listening for anyone serious about biohacking, hacking human performance, longevity, mitochondria, neuroplasticity, nootropics, metabolism, functional medicine, anti-aging strategies, supplements, and living Smarter Not Harder, ideally with a cup of Danger Coffee in hand. You'll Learn: • Why your glutes and skeletal muscle are critical drivers of longevity and brain health • Why intermuscular fat can matter more than body fat percentage for metabolic dysfunction • How strength training improves neuroplasticity, cognition, and emotional resilience • Why protein needs increase with age and why outdated limits can hold you back • What GLP-1 drugs get right, where they fail, and how to protect muscle span • Why progressive stimulus beats lifting heavy for long-term strength and injury prevention • How sleep optimization and recovery support mitochondria and human performance • How building muscle creates clarity, resilience, and better decision-making Dave Asprey is a four time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Thank you to our sponsors! Quantum Upgrade | Support your brain, energy, focus, sleep, and recovery with Quantum Upgrade, a 24/7 streaming quantum energy service designed to work continuously in the background. Try it free for 15 days with no credit card required: https://quantumupgrade.io/DAVE Screenfit | Get your at-home eye training program for 40% off using code DAVE at https://www.screenfit.com/dave BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle. KillSwitch | If you're ready for the best sleep of your life, order now at https://www.switchsupplements.com and use code DAVE for 20% off. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: muscle longevity organ, glutes brain health, strength training longevity podcast, muscle span aging, intermuscular fat metabolism, IMAT insulin resistance, skeletal muscle brain function, neuroplasticity strength training, protein intake aging, high protein diet longevity, metabolism muscle health, mitochondria muscle brain, muscle centric medicine podcast, gabrielle lyon podcast, forever strong playbook, women strength training longevity, GLP-1 muscle loss, sarcopenia aging prevention, resistance training brain health, sleep optimization muscle recovery, fasting ketosis muscle health, carnivore diet muscle metabolism, functional medicine muscle health, biohacking strength longevity, human performance muscle, anti-aging strength training, supplements muscle recovery, progressive stimulus training, blood flow restriction training, muscle resilience mindset Resources: • Get Gabrielle's NEW book Forever Strong: https://drgabriellelyon.com/forever-strong/ • Gabrielle's Website: https://drgabriellelyon.com/ • Follow Gabrielle's Instagram: https://www.instagram.com/drgabriellelyon/ • Gabrielles Youtube: https://www.youtube.com/@DrGabrielleLyon • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 – Introduction 1:01 – The Playbook vs Workbook 3:47 – Protein & Metabolic Health 6:21 – Mindset & Negativity 7:20 – Histamines & Hot Flashes 10:49 – Women & Strength Training 13:40 – Connective Tissue & EDS 16:15 – Muscle Span & Aging 19:41 – Training for Kids 21:55 – Pain Cave & Discomfort 25:25 – Emotional Regulation 29:46 – Resilience & Dating 32:11 – Building Friction & Discernment 35:47 – Self-Denial vs Awareness 41:03 – Mitochondria & Energy 42:46 – Bigger Booty, Bigger Brain 44:52 – Body Fat vs IMAT 49:01 – Measuring Muscle Health 52:08 – GLP-1s & Muscle Loss 56:12 – Protein Absorption Myths 59:30 – mTOR & Protein 1:01:29 – Closing Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Peter Cowan and I discuss the surge in non-contact soft-tissue injuries of 49ers players and possible mechanisms including chronic magnetic field exposure from nearby electrical substation, circadian rhythm disruption causing mitochondrial dysfunction, impaired collagen repair and delayed healing.Peter Cowan is a software developer, health coach with an interest in applied circadian biology and EMF mitigating consultant. PODCAST SPONSORS

In this episode of the Soil Sisters Podcast, meet Dr. Ben Edwards, founder and CEO of Veritas Medical and Veritas Wellness in Lubbock, Texas. Dr. Edwards shares his path from conventional family medicine to a holistic, root-cause resolution approach to health and wellness. He discusses his transformation following a divine intervention that guided him to realize the flaws in conventional chronic disease management. The conversation explores real patient experiences and the importance of nutrition, hydration, movement, and peace—The four pillars taught at Veritas Wellness. Dr. Ben also explains in practical terms the role of the gut microbiome and mitochondrial health in foundational wellbeing. You'll gain insights into the power of mindset, the significant impact of epigenetics, and the interconnectedness of soil health and human health. Tune in to learn how you're the cure you've been looking for.MEET OUR GUEST: Dr. Ben Edwards has over 20+ years in the medical field. He is the founder and CEO of Veritas Medical and Veritas Wellness in Lubbock, TX. And he also hosts the "You're The Cure" Podcast (Top 75 Functional Health Podcast), where he educates people on getting to the root cause of disease, and teaching them how to NOT NEED a Doctor!Raised in Belton, TX, Dr. Edwards holds degrees from Baylor University and the University of Texas Medical School at Houston. He completed his residency at Waco's McLennan County Medical Education and Research Foundation before moving to West Texas in 2005 with his wife Jamie where Dr. Edwards was the only doctor in the county at the Garza County Health Clinic. After 7 years of practicing conventional medicine, a divine appointment opened his eyes to root cause resolution medicine.TIME STAMPS:00:00 Welcome to the Soil Sisters Podcast00:43 Introducing Dr. Ben Edwards00:52 Dr. Ben's Medical Journey04:17 A Divine Appointment  08:39 Challenging Conventional Medicine09:18 A Nurse Practitioner's Transformation14:39 The Power of Alternative Medicine27:10 Personal Testimonies and Success Stories31:01 Integrative Approaches to Cancer Treatment33:23 Transitioning to Root Cause Resolution37:14 A New Beginning: Starting Veritas Medical38:59 Overcoming Challenges: Building the Practice40:41 The Insurance Dilemma: Breaking Free from The System41:34 The Power of Mitochondria and Microbiome42:47 Launching Veritas Wellness: Health Coaching Revolution44:25 The Four Pillars of Wellness59:54 Epigenetics: Taking Control of Your Health01:09:43 Healthy Soil, Healthy Gut01:12:48 Conclusion: Empowering Health and Wellness

In the third installment of the Skin Anarchy and Timeline Masterclass, Dr. Ekta Yadav sits down with Dr. Brad Currier, Manager of Clinical Trials at Timeline, for a behind-the-scenes look at what real evidence in longevity science and skincare actually requires.With a foundation in muscle physiology, exercise science, and aging research, Dr. Currier brings a performance-driven lens to longevity — reframing skin not as a cosmetic surface, but as a mitochondria-dense longevity organ, biologically linked to muscle health, metabolic resilience, and cellular energy. The episode explores why mitochondrial function may be one of the most underappreciated drivers of how both skin and the body age.At the center of the conversation is Timeline's research on urolithin A, a postbiotic shown to support mitochondrial renewal. Rather than relying on marketing narratives, Timeline has built its platform on mechanism-first science, translating years of cellular research into human clinical trials — including biopsy-based studies that reveal measurable changes in collagen synthesis and skin structure.Dr. Currier also pulls back the curtain on the truth about clinical claims in beauty — explaining why many “clinically tested” labels lack rigor, how underpowered or biased studies distort results, and what separates meaningful, published human data from perception-based marketing. From wrinkle depth to hydration to barrier function, he outlines how Timeline measures outcomes that reflect real biological change — not just surface-level improvement.The episode ultimately reframes longevity as precision science, not hype — emphasizing the importance of human trials, mitochondrial health, and transparent evidence in an industry flooded with buzzwords.Listen to the full episode of Skin Anarchy to hear Dr. Brad Currier unpack what clinical validation should look like — and why the future of longevity skincare depends on measurable biology, not marketing promises.SHOP TIMELINEDon't forget to subscribe to Skin Anarchy on Apple Podcasts, Spotify, or your preferred platform.Reach out to us through email with any questions.Sign up for our newsletter!Shop all our episodes and products mentioned through our ShopMy Shelf!Support the show

Today I'm joined by neuroscientist and mitochondrial health expert Siobhan Mitchell to cut through the noise around mitochondria, inflammation, NAD, and what actually matters for energy, recovery, and brain health in midlife We unpack why mitochondria are not just “battery packs”, they are a master regulator of oxidative stress, immune signalling, and cellular aging. Siobhan explains the difference between hormetic stress that upgrades your system (like training) versus chronic stress that drains it WHAT YOU'LL LEARN: • What mitochondria actually do, beyond “energy production”  • Mitophagy and mitochondrial biogenesis, and why both decline with age  • The difference between hormetic stress (exercise) and chronic stress (modern life)  • Why mitochondrial dysfunction can drive inflammation and immune overactivation  • How brain energy demand and oestrogen loss intersect in menopause symptoms  • CD38, inflammation, and why staying lean matters for NAD preservation  • Why NAD precursors can be wasted, and what supports conversion inside the cell  • The practical take on timing, training, and recovery support TIMESTAMPS 00:01 Mitochondria, ATP, and the oxidative stress trade-off  04:14 Mitophagy, mitochondrial biogenesis, and aging  16:13 Mitochondria as immune regulators, inflammation and cytokines  23:09 Brain energy, menopause, oestrogen, and cognitive decline mechanisms  29:33 NAD explained, CD38, and why NAD drops with age  48:56 NAD, GLUT4, insulin sensitivity, and perimenopause metabolism  53:19 Where to learn more, discount code, and closing VALUABLE RESOURCES ⁠Join The High Performance Health Community⁠ ⁠Click here⁠ for discounts on all the products I personally use and recommend A BIG thank you to our sponsors who make the show possible Get 10% off MitoQ NAD+ - www.mitoq.com with code ANGELA Get 35% off Timeline Mitopure by visiting this link while the offer lasts - https://www.timeline.com/promotions/angela35 Upgrade your cellular health - get 20% off Beam Minerals at http://beamminerals.com/ANGELA & use code ANGELA at checkout ABOUT THE GUEST Dr Siobhan Mitchell - Chief Scientific Officer - MitoQ Siobhan is the Chief Scientific Officer at MitoQ. She completed her PhD at SUNY Albany and a post-doctoral fellowship in brain ageing at the University of Washington. Siobhan has held roles at the three largest food companies in the world (Unilever, Nestlé, and PepsiCo), where she conducted trials in Europe, North America, and Asia, investigating the effects of nutrition on cognitive decline, mood, and performance. Additionally, she was Senior Director of Research at Noom, where she led a team investigating the behavioural and health effects of weight loss and mental health ABOUT THE HOST Angela Foster is an award winning Nutritionist, Health & Performance Coach, Speaker and Host of the High Performance Health podcast. A former Corporate lawyer turned industry leader in biohacking and health optimisation for women, Angela has been featured in various media including Huff Post, Runners world, The Health Optimisation Summit, BrainTap, The Women's Biohacking Conference, Livestrong & Natural Health Magazine. Angela is the creator of BioSyncing®️ a blueprint for ambitious entrepreneurial women to biohack their health so they can 10X how they show up .without burning out. CONTACT DETAILS ⁠Instagram⁠ ⁠Facebook⁠ ⁠LinkedIn⁠ Disclaimer: The High Performance Health Podcast is for general information purposes only and do not constitute the practice of professional or coaching advice and no client relationship is formed. The use of information on this podcast, or materials linked from this podcast is at the user's own risk. The content of this podcast is not intended to be a substitute for medical or other professional advice, diagnosis, or treatment. Users should seek the assistance of their medical doctor or other health care professional for before taking any steps to implement any of the items discussed in this podcast.

In this episode, we're joined by Dr. Darren Schmidt, a chiropractor who has dedicated his practice exclusively to clinical nutrition and nutritional healing. He is the founder of the Nutritional Healing Center of Ann Arbor and a nationally recognized speaker on chronic illness and metabolic health. Dr. Schmidt's nontraditional path into healthcare stems from his rejection of conventional medical models that have failed. Drawing from over 30 years of clinical experience, he explains why many people never fully recover from chronic illness — and how addressing cellular function, toxin overload, and nutritional deficiencies can change that… We also dive into his 2024 book, Optimal Health: The 7 Step System to Transforming Your Health with Nutritional Healing, where he outlines the fundamental causes of chronic disease, including the often-misunderstood difference between detoxification and drainage. Dr. Schmidt breaks down how issues like mold exposure, parasites, mitochondrial dysfunction, and metabolic stress quietly undermine health. This discussion covers: What separates Dr. Schmidt from other doctors. How diet and supplements help people get well. The unique mechanisms of chronic illness. The 7-step framework from Optimal Health Follow Dr. Schmidt on social media: YouTube • TikTok • Instagram • Facebook

Why do so many people struggle with fatigue, stubborn weight gain, hormone issues, and burnout — even when they're eating “clean” and training hard? In this episode, we break down the real reason your body isn't healing and why most health advice fails to address the root cause.Joined by Lindsay Perry, this conversation dives deep into a systems-based approach to health, exploring how the gut, liver, hormones, nervous system, sleep, and stress all work together to control energy, metabolism, and long-term results.Rather than focusing on symptoms, trends, or extreme diets, this episode explains what's happening under the hood — from ATP production and mitochondrial function to cortisol regulation, nervous system balance, and metabolic flexibility. You'll learn why pushing harder often backfires and how chronic stress quietly sabotages recovery, fat loss, and hormone health.We cover:Why gut and liver health are foundational for hormones and energyHow stress and nervous system dysregulation block healing and fat lossThe role of sleep and circadian rhythm in metabolism and recoveryWhy detoxification and elimination are biological processes — not fadsHow to fuel properly based on stress, activity, and current health stateLindsay Perry brings real-world coaching insight throughout the episode, helping connect science with practical application for people who feel stuck despite doing “everything right.”If you're tired of surface-level health advice and want a clear, root-cause explanation of how the body actually heals, this episode will change how you think about health, fitness, and recovery.00:00 – Introduction & Why Most People Aren't Healing00:41 – The “March Method” & Root-Cause Health Explained01:02 – ATP, Mitochondria & Cellular Energy Basics01:19 – Hormones, Cycles & Why Balance Matters02:44 – Detox, Elimination & Why the Body Gets Stuck04:14 – Cold Exposure, Stress Adaptation & Recovery05:50 – Stress Load, Burnout & Early Cortisol Discussion07:55 – Fueling the Body: Fat vs Carbs Explained10:57 – Sleep, Circadian Rhythm & Metabolic Health12:12 – Gut Health: The Foundation of Healing15:48 – Liver Function, Detox Pathways & Hormones18:35 – Inflammation, Energy Deficits & Fatigue21:30 – Nervous System Regulation & Chronic Stress24:35 – Cortisol, Survival Mode & Weight Loss Resistance28:10 – Why Pushing Harder Makes Things Worse32:24 – Metabolic Flexibility & Long-Term Healing34:27 – Nervous System Reset & Final Takeaways35:57 – Closing ThoughtsDisclaimer:The information discussed in this episode is for educational and informational purposes only and is not intended as medical advice. This content is not a substitute for professional medical diagnosis, treatment, or guidance. Always consult with a qualified healthcare provider before making changes to your diet, lifestyle, supplements, or health practices.

Today, I'm joined by the incredible Anthony Castore, a trailblazer who fuses elite strength coaching with deep cellular medicine. In our conversation, Anthony shares his journey from a young athlete determined to defy genetic odds to becoming an expert in both physical training and the nuanced science of peptides, mitochondria, and bioregulators.   Use code NAT10 for 10% off products at https://alchemiqlabs.com/   Episode Timestamps: Welcome and episode introduction ... 00:00:00 Anthony Castore's path from strength coaching to cellular medicine ... 00:05:55 Connecting strength training with cellular pathways (AMPK, mTOR) ... 00:12:27 Explaining and balancing AMPK and mTOR for performance ... 00:13:03 Training strategies: Metabolic, hypertrophy, and neural approaches ... 00:18:18 Building a solid foundation: Lifestyle, training, nutrition, peptides ... 00:23:04 Assessing recovery capacity and individualizing protocols ... 00:26:02 Mitochondrial fission, fusion, and targeted adaptation ... 00:29:57 Optimizing muscle gain and fat loss through calories and recovery ... 00:31:00 Differentiating bodybuilder vs. longevity approaches ... 00:34:44 Integrating peptides and support molecules into routines ... 00:40:44 Ketone esters and mitochondrial peptide interventions ... 00:41:20 Cautions on stacking and combining interventions ... 00:54:04 Lessons learned from overdoing interventions ... 01:05:02   Our Amazing Sponsors: Vitali - combines pharmaceutical-grade copper peptides with zero-age exosomes to support clearer cellular signaling and long-term skin resilience, working with your biology instead of forcing change. Visit VitaliSkincare.com and use code NAT20 for 20% off.   BEAM Minerals - Low energy often starts in the mitochondria. Support cellular energy with a bioavailable liquid mineral supplement — and get 20% off at beamminerals.com with code NAT20.   Complete Liver Complex by LVLUP Health - supports your liver's natural detox pathways so your body can reset after the holidays without suffering. Go to lvluphealth.com and use code NAT for 20% off.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Full Show Notes: https://bengreenfieldlife.com/lavalle/ In this episode, I sit down with the legendary clinical pharmacist Jim LaValle for a fascinating exploration of some of the most innovative approaches to health, performance, and longevity. We discuss everything from peptides and small molecules for mitochondrial and kidney support to the science behind improving VO2 max, brain function, sleep, and more. Jim LaValle unpacks his decades of experience, shares cutting-edge research on metabolic health, and explains the power of his Metabolic Code test—which I recently tried myself—for identifying and addressing the biggest bottlenecks in your health journey. Throughout our conversation, we swap stories about nutrition missteps (think gallons of dairy and endless antibiotics), dive into the practical application of peptides like KPV, BPC-157, and lorazotide for healing the gut, and examine trends Jim repeatedly sees even in high performers—like stress-driven hormone changes and sneaky signs of inflammation. If you’re curious about how personalized lab testing, wearable data, and smart supplementation can help you feel better, perform better, and age powerfully, you’ll love the insights in this episode. James "Jim" B. LaValle, B.S.Pharm, CCN, MT, DHM, DHPh, is an internationally recognized clinical pharmacist, author, and board-certified clinical nutritionist, with over 40 years of clinical experience in natural products, lifestyle, drug/nutrient depletion, compounding pharmacy, and peptides. Episode Sponsors: Truvaga: Balance your nervous system naturally with Truvaga's vagus nerve stimulator. Visit Truvaga.com/Greenfield and use code GREENFIELD30 to save $30 off any Truvaga device. Calm your mind, focus better, and recover faster in just two minutes. ZBiotics Pre-Alcohol Probiotic: The world's first genetically engineered probiotic that helps break down the toxic byproduct of alcohol, Zbiotics Pre-Alcohol allows you to enjoy your night out and feel great the next day. Order with the confidence of a 100% money-back guarantee and 15% off your first order at zbiotics.com/BEN15. TRIUMPH Coaching: Join me for one-on-one coaching with me and my hand-picked team, custom-built around your labs, your lifestyle, and goals, until you actually hit them. No guesswork. Just results. If you’re finally ready to stop wasting time and money and start living the boundless life you know is possible, go to jointriumphcoaching.com and book your call. Just Thrive: Take the Just Thrive FEEL BETTER challenge today, and save 20% on your first Gut Essentials Bundle. Just Thrive Probiotic is the only probiotic clinically proven to arrive 100% alive in your gut, reducing bloat, better energy, and even clearing skin. Digestive Bitters packs 12 science-backed herbs in one tasteless capsule that jumpstarts your digestion and supports GLP-1 production so cravings don’t control you. Visit justthrivehealth.com/BEN and save 20% with promo code BEN. See the difference for yourself or get a full product refund, no questions asked. Boundless Bar: If you’re ready to fuel workouts, sharpen your focus, and support whole-body vitality, grab your Boundless Bars now at boundlessbar.com —and save 10% when you sign up for a Boundless Bar subscription.See omnystudio.com/listener for privacy information.

This week, we are joined by Chris Masterjohn, PhD. Chris is a nutritional scientist, a former professor, and the founder of Mitome. With a PhD in nutritional science and years of research in mitochondrial biology, Chris's work focuses on translating peer-reviewed science into practical tools for human health. At Mitome, Dr. Masterjohn pioneered the first analysis designed to measure mitochondrial respiratory chain function directly, identifying individual energy bottlenecks and guiding personalized science-backed protocols to optimize the system responsible for over 90% of cellular energy production. His mission is to bring mitochondrial testing out of the rare disease space and into everyday health. In this interview, we discuss why so little is understood about the role serotonin plays in the body and how our mitochondria might play a part in the experince of antidepressant withdrawal. *** Thank you for being with us to listen to the podcast and read our articles this year. MIA is funded entirely by reader donations. If you value MIA, please help us continue to survive and grow. https://www.madinamerica.com/donate/ To find the Mad in America podcast on your preferred podcast player, click here: https://pod.link/1212789850 © Mad in America 2025. Produced by James Moore https://www.jmaudio.org

Your body does not fail all at once. Aging starts when cells quietly shift into survival mode and never come back out. In this episode, you go inside the thinking of a true medical outlier to understand how stress, travel, toxins, and metabolic overload reprogram cells, shut down energy, and accelerate aging, and how restoring mitochondrial function can reverse that trajectory from the inside out. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Theodore Achacoso and Boomer Anderson, leaders in Health Optimization Medicine and Practice. Dr. Achacoso is a physician-scientist and the founding pioneer of Health Optimization Medicine, known for his work on cellular networks, metabolomics, and mitochondrial function. Boomer Anderson is the CEO of Smarter Not Harder and Troscriptions, where he focuses on translating complex biology into practical tools for human performance and longevity. Together, they unpack how cells respond to perceived threats through the Cell Danger Response, why mitochondria control energy, inflammation, and repair, and why chasing disease labels misses the real drivers of aging. The discussion covers methylene blue as an electron recycler, why LDL cholesterol plays a role in detoxification and immune signaling, how fasting and ketosis shift metabolism between repair and growth, and why sleep optimization, circadian rhythm, and light exposure matter even more when you travel. They also explore neuroplasticity, consciousness, nootropics, supplements, and why health optimization works best when you restore balance instead of forcing outcomes. You'll Learn: • What the Cell Danger Response is and how it reshapes aging and performance • How mitochondria sense stress before symptoms appear • Why cellular energy controls resilience, sleep, and longevity • How methylene blue supports mitochondrial electron flow • Why fasting and ketosis shift metabolism between repair and growth • How travel, light, and circadian disruption affect aging • Why very low LDL can impair detoxification and immune signaling • Why real anti-aging starts at the cellular level, not with disease labels Thank you to our sponsors! AquaTru | Go to https://aquatruwater.com/daveasprey and save $100 on all AquaTru water purifiers. Screenfit | Get your at-home eye training program for 40% off using code DAVE at www.screenfit.com/dave. Puori | Use code DAVE at puori.com/DAVE to get 32% off your Puori Fish Oil when you start a subscription. You save more than $18. fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: cell danger response podcast, mitochondria aging, mitochondrial dysfunction aging, health optimization medicine, dr ted achacoso, boomer anderson, troscriptions, troscriptions methylene blue, methylene blue mitochondria, methylene blue biohacking, cellular aging podcast, anti aging mitochondria, metabolic stress aging, fasting ketosis metabolism, mitochondrial energy production, neuroplasticity mitochondria, sleep optimization aging, functional medicine mitochondria, smarter not harder biohacking, dave asprey mitochondria Resources: • Get A Discount On All Troscription Products with code ‘dave' at: https://troscriptions.com/ • Learn More About Methylene Blue From My Full Masterclass Covering The Topic: https://daveasprey.com/mb/ • Discover More About The ‘Health Optimization Medicine and Practice' From Our Guests: https://homehope.org/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 – Trailer 1:25 – Introduction & Guest Background 3:11 – Health Optimization Medicine Origins 4:26 – Root Causes of Health vs Disease 6:15 – Biohacking & Self-Experimentation 8:19 – Medicinal Plants & Nootropics 11:25 – Travel & Jet Lag Solutions 13:42 – Cell Danger Response 17:38 – Metabolites & Cellular Health 18:57 – LDL & Lipopolysaccharides 20:42 – Cellular Model & First Principles 22:55 – Consciousness & Mitochondria 25:46 – Nanotechnology Research 28:55 – Giving Back & Service 31:17 – Blue Cannatine Development 34:48 – Methylene Blue Products 36:22 – Metformin Discussion 38:00 – Dosing & Cordycepin 41:25 – Closing & Discount Code See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dorian Yates is a former professional bodybuilder, six-time Mr. Olympia winner and a pioneer of high-intensity, low-volume training for building muscle size and strength. He explains how anyone can vastly improve their fitness, mindset and appearance by training with weights just two or three days per week for less than an hour. We also discuss how to determine your natural strengths and passions and select which life path is right for you. Dorian also shares his journey and transformation from wayward youth to world champion athlete, his exploration of psychedelics, views on cannabis and on longevity and health optimization more generally. The knowledge and wisdom Dorian shares is valuable to men and women of all ages. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David Protein: https://davidprotein.com/huberman Joovv: https://joovv.com/huberman Our Place: https://fromourplace.com/huberman LMNT: https://drinklmnt.com/huberman Function Health: https://functionhealth.com/huberman Timestamps (00:00:00) Dorian Yates (00:03:17) High-Intensity Training, Bodybuilding, Blood & Guts (00:09:15) Muscular Failure, Stimulate & Recover; Anabolics (00:12:04) Sponsors: David & Joovv (00:14:33) Muscle Pump, Stimulus; Recovery Weeks (00:17:32) Beginners & Learning Correct Mechanics; Diabetes (00:22:13) Research vs Real World, Tool: High-Intensity, Low-Volume Training, HIIT Sprints (00:28:53) Bodybuilding Journey, Reading, Training Logs, Aspiration, Parents (00:39:21) Sponsors: AG1 & Our Place (00:42:46) TRT, Steroids, Genetics, Early Bodybuilding Career; Tool: Steroid Risks (00:53:57) Father & Son Relationship; Training Evolution (00:58:31) Workout Intensity & Motivation, Self-Mastery, Transforming Anger (01:05:34) Death; Opportunity Analysis; Bodybuilders, Steroids & Diuretics (01:12:18) Human Possibility, Fitness & Health Progression, Nutrition (01:16:05) Sponsor: LMNT (01:17:26) Mike Mentzer (01:20:42) 1992-1993 Mr. Olympia, Underdog vs Favorite Mindset (01:30:22) Inspiration & Achieving Goal; Retirement, Transition & Identity (01:38:52) Flexibility, Winning vs Loving the Process (01:43:08) Aging, Exercise & Posture (01:46:34) Sponsor: Function (01:48:22) Losing Muscle & Diet Change; Breathing; Health & Mind (01:52:02) Psychedelics, DMT, Ayahuasca, Perspective & Connection (02:01:20) Risks, Research & Psychedelics; Brain Plasticity, Perspective Change (02:06:23) Sunlight & Mood, Schizophrenia, Dopamine, Mitochondria (02:12:15) Cannabis, Smoking & Health; Cancer; Breathwork (02:19:34) Cannabis & Motivation, Individual Variation, THC Levels (02:25:22) Plant Medicine, Kratom, Natural Plants vs Extracts (02:28:53) Training for Women, Losing Fat & Resistance Training; Resilience (02:33:52) DY Nutrition, Supplements; Life Purpose & Consciousness (02:44:40) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

Video: https://www.youtube.com/watch?v=A6ymQgVLC5cAutism & Parkinson's https://youtu.be/1E53ZYehUCU?si=69pKeFSKi07GGsATHypothyroid Biomarker https://youtu.be/X6CxX9kA6b0?si=Bkr8ZKooNdie-N6IDr. Kristen Lyall, ScD https://youtu.be/cjBR8m82KZQ?si=C-Tclr25oBbid7qGNicole Rincon & links to her other episodes in notes https://youtu.be/jRd7rE38W90?si=i8CvVutA4a1K9NzeDaylight Computer Company, use "autism" for $50 off at https://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount at https://getchroma.co/?ref=autismFig Tree Christian Golf Apparel & Accessories, use "autism" for 10% discount at https://figtreegolf.com/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount at https://thecognity.com00:00 Serotonin Recap: thalamocortical connections (esp. S1 somatosensory)02:41 Aromatic Amino Acids & UV-sensitive aromatic benzene rings04:56 Personal Sunlight Reversal Host reversed Hashimoto's (2005–2024) via increased sunlight07:58 Cell-Level Roles Serotonin drives neurogenesis, migration, dendrites/spines; T3 matures organelles, myelination & cellular energy11:00 Maternal Thyroid Dependency Fetus relies on maternal T3/T4 until ~weeks 16–20; hypothyroidism as easy, modifiable biomarker for autism/Parkinson's13:07 Substantia Nigra & Basal Ganglia Neuromelanin/dopamine loss in substantia nigra links autism & Parkinson's; disrupts basal ganglia go/no-go orchestration15:44 Mitochondria & Melanin Energy Cytochrome c oxidase produces H2O in ETC; melanin + water coupling provides power 18:00 Hypothyroidism Biomarker Call Undisputed, simple-to-check risk factor; urgent prenatal thyroid screening & sunlight exposure needed20:36 Modern Environment Impact Blue light/low sunlight blocks synthesis; upstream fixes (reflexes, thyroid checks, sunlight) offer prevention/recovery potential22:15 Serotonin & T3 Synergy Serotonin architects connections; T3 engineers cell/organelle maturity & myelination; combined deficits cascade into autism/Parkinson's24:00 Substantia Nigra Detail Loss of neuromelanin/dopamine in substantia nigra (mesencephalon) impairs basal ganglia; ties to movement disorders in both conditions25:44 Mitochondria Water Production Cytochrome c oxidase (complex IV) generates H2O; melanin & water 27:58 Final Synthesis & Implications Serotonin + T3 critical for cell development/myelination; maternal hypothyroidism disrupts both autism/Parkinson's riskX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

This week I interviewed Dr. Sam Shay. Dr Shay is a functional medicine expert, speaker, and stand-up comic.  With over 25 years of experience in nutrition science, mind-body medicine, and genetic analysis, Dr. Sam guides others in building personalized health strategies rooted in their unique biology. We discussed functional approaches to hypo/hyperthyroidism along with:- the importance of mitochondrial health- using genetics to guide nutrition- carb tolerance testsand his one tip to get your body back to what it once was!Connect with Dr. Shay:https://drsamshay.com/-------How to Take Simple Steps to Reclaim the Body, Energy, and Strength You Had 10-15 Years Ago Using My Stepladder System:https://www.stepladdersystem.com/FREE Nutrition Cheatsheets:https://brian-getleaneatclean.beehiiv.com/subscribeClick to book a FREE 15 minute consult with Brian:https://calendly.com/bdgryn/15min------------Interested in Upgrading your Mitochondria, Improving Energy and Sleep! Check out Troscriptions: https://bit.ly/4ik5kK5Use Discount Code for 10% OFF: EATCLEAN----Watch Get Lean Eat Clean podcast video episodes on YouTube!YouTube.com/@briangryn3680----B.rad Whey Protein Isolate Superfuel:The Best Protein on The Planet! Available in Two Delicious Flavors: Vanilla Bean and Cocoa BeanUse Coupon Code glec10off for 10% off your order!https://a.co/d/731gssV----My favorite health bars with clean ingredients!https://www.eatprima.com/BRIAN6816310% OFF with this link!

In this episode of Wellness at the Speed of Light, Dr. Stefano Sinicropi is joined by board-certified neurologist Dr. Theodore Henderson for an educational discussion on brain health, cellular energy, and emerging approaches in neurology. The conversation centers on how light-based therapies, often referred to as photobiomodulation, are being studied for their potential role in supporting brain function. Dr. Henderson explains how mitochondria, the structures responsible for cellular energy production, are closely linked to cognitive performance, memory, and overall neurological health. When mitochondrial function is compromised, it may contribute to cognitive decline and neurological stress over time. Dr. Sinicropi and Dr. Henderson explore how this science is being examined in the context of neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease, and traumatic brain injury, with a focus on understanding mechanisms rather than promoting treatments. The episode discusses why traditional models of care have often overlooked cellular energy and light-based research, and how ongoing scientific inquiry is expanding the way clinicians think about brain resilience and recovery. This episode is designed for healthcare professionals, patients, caregivers, and listeners interested in neuroscience, brain wellness, and the future of integrative neurological care. It offers a clear, accessible explanation of complex concepts and invites thoughtful consideration of where neurological research is heading. Rather than making promises, this conversation encourages curiosity, informed dialogue, and a deeper understanding of how advancing science may shape the future of brain health.

Is mitochondrial decline the hidden blueprint that decides how fast your body ages? Josh Trent welcomes Dr. Brad Currier, PhD, Clinical Scientist, to the Wellness + Wisdom Podcast, episode 793, to unpack how mitochondrial health is passed through generations, why modern environments and sedentary living accelerate aging, how mitophagy and Urolithin A restore cellular energy, why gut health blocks or enables longevity, and how exercise plus targeted supplementation can fundamentally shift mood, vitality, and long term health from the inside out. 30% Off Mitopure (Timeline Nutrition) The first clinically tested Urolithin A supplement Mitopure® is a highly pure form of Urolithin A, a postbiotic clinically shown to energize cells, increase muscle strength, and improve endurance. And this is just the beginning. New studies continuously explore and prove the incredible potential of Urolithin A. Few people can get enough Urolithin A from diet alone. Mitopure unlocks 6X the dose of Urolithin A when compared to dietary sources such as pomegranate juice, without the sugar. Mitochondria, our cellular powerhouses, are constantly renewed to fulfill the vast energy demands of cells. As we age, mitochondrial function declines, starting as early as our 30s. Mitopure stimulates the mitochondrial renewal process to protect cells from age-associated decline. Get Mitopure Today Save 30% with code JOSH at checkout In This Episode, Dr. Brad Currier Uncovers: [01:10] How to Optimize Mitochondrial Health How our mitochondrial DNA is passed from mothers to children. The functions of mitochondria in the human body. How our environment affects our mitochondria. Why UV radiation from the sun damages proteins in our cells. How sedentary lifestyle impact mitochondrial health. Resources: Dr. Brad Currier, PhD Timeline Nutrition - 30% off with code JOSH  [08:35] Intergenerational Mitochondrial Health How mitochondrial health is impacted by multiple generations that came before us. Why we're impacted by seven generations before us, and we impact seven generations after us. The importance of nurturing our mitochondrial health. Resources: It Didn't Start with You by Mark Wolynn [12:55] The Cause of Aging What causes faster aging. How our cells become unhealthy and age. Why our cell turnover slows down as we age. How mitochondria break down and impact our energy levels. Resources: 781 Pedram Shojai | Anti-Aging Cult: Why Trying To Live Forever Devours Your Soul [16:55] The Importance of Urolithin A The role of postbiotics in digestion. Why we need Urolithin A for optimal health. How Urolithin A was discovered. Resources: Outwitting The Devil by Napoleon Hill [20:55] You Need to Fix Your Microbiome Why we have to take supplements to maintain our health. How the microbiome blocks production of Urolithin A. Why most people's gut microbiome is damaged. How our gut microbiome lacks diversity compared. [24:15] Gut-Brain Axis How the gut-brain axis is linked to many diseases. Why mitochondria can impact different systems of the body. The importance of supplementing Urolithin A. Why food cannot help us produce more Urolithin A. How aging affects protein absorption. [29:35] Activate Mitophagy to Stop Aging Why Mitopure is the only clinically proven supplement to activate mitophagy. The three phases of the mitochondria's life cycle. Why removing cellular residue prevents aging. How healthy mitochondria can help us live a better life. Why renewing cellular energy requires consistency. [36:05] Scientific Data Behind Mitochondrial Health How mitochondrial health impacts mood and mental health. Why Timeline Nutrition continues running new clinical studies. How repeated scientific research proves whether something truly works or not. Why they publish all of their studies online. [43:40] The Power of Exercise Why professional athletes have a higher risk of heart attack. How exercise is the best tool for health and longevity. Why combining Mitopure with exercise increases mitochondrial health. How weightlifting helps us create new cells. [50:20] The Fundamentals of Health How Brad takes care of his own health. Why exercise is the most important tool for him. The role of a good diet and sleep in our health. [55:20] Change Is Counter-Intuitive Why change can feel counterintuitive at first. The importance of allowing ourselves to feel uncomfortable. How we can't often know for sure what tools or supplements are best for us. "Poor quality food and pollutants in our environment ultimately converge on the mitochondria and have an impact on its ability to produce energy. When we have this accumulation of debris in our cells, they don't work as well and they start releasing toxins that impact cells around them. " — Dr. Brad Currier, PhD Leave Wellness + Wisdom a Review on Apple Podcasts All Resources From This Episode Dr. Brad Currier, PhD Timeline Nutrition - 30% off with code JOSH  It Didn't Start with You by Mark Wolynn 781 Pedram Shojai | Anti-Aging Cult: Why Trying To Live Forever Devours Your Soul Outwitting The Devil by Napoleon Hill Josh's Trusted Products | Up To 40% Off Shop All Products Biohacking⁠ ❤️ WAVwatch - Now 15% off with JOSH100

Save 20% on all Nuzest Products WORLDWIDE with the code MIKKIPEDIA at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comThis week on the podcast, Mikki speaks to Curtis Gillespie Sayers for a wide-ranging and grounded conversation on chronic illness, mitochondrial health, and what real healing actually requires.Curtis shares his own health journey — from being in and out of hospital from a young age with severe sleep apnoea, cardiometabolic risk, and long-standing physiological stress, to entering the health space through bodybuilding before realising that looking fit and being well are not the same thing.Together, they explore why many people remain stuck despite doing “all the right things,” and how healing often fails not because of a lack of effort, but because the body is still operating in a defensive state. They discuss the physiology that keeps the body stuck in survival rather than being able to heal. They also dive into peptides, what is and isn't appropriate and Curtis' recommendations for out of the box treatments. Curtis Gillespie Sayers is a health practitioner and systems thinker specialising in mitochondrial health, nervous system regulation, and recovery from chronic illness.After spending much of his early life in and out of hospital with significant respiratory and cardiometabolic complications — including severe sleep apnoea, hypertension, dyslipidaemia, and pre-diabetic markers — Curtis entered the health space initially through bodybuilding. While improving his physique helped some symptoms, it also revealed a deeper truth: external fitness does not guarantee internal health.Driven by a desire to understand what was happening beneath the surface, Curtis shifted his focus toward the interaction between mitochondria, the nervous system, immune signalling, and environmental inputs such as light, sleep, and stress. His work now centres on helping people who feel “stuck” — those who have tried diets, supplements, and protocols without lasting improvement — by addressing the biological signals that determine whether the body can actually heal.Curtis takes a pragmatic, data-informed approach, viewing tools like nutrition, supplements, and peptide therapy as supportive levers rather than shortcuts, and emphasising the importance of safety, adequacy, and rhythm in long-term recovery.Curtis https://lifestylempowerment.ca/Curtis https://www.instagram.com/funct.med.curtis/ Curranz Supplement: Use code MIKKIPEDIA to get 20% off your first order - go to www.curranz.co.nz  or www.curranz.co.uk to order yours Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwilliden

Did you know that the millions of tiny mitochondria in your body are considered 'social beings'? Yes, these tiny organelles don't just generate energy for the cell. They sense the environment, form dynamic groups, communicate with each other, divide labor among themselves, and even heal one another. Learn about these fascinating organelles from a world expert, and hear what we can do to optimize their behavior in our bodies. Then hear an interview with a Harvard physician about the role of dietary protein in our overall health. How much protein should we really consume every day? These interviews are courtesy of the 'Big Picture Science' podcast, produced by the SETI Institute on October 6, 2025: https://radio.seti.org/episodes/skeptic-check-health-fads. ‘Bench Talk: The Week in Science' is a weekly program that airs on WFMP Louisville FORward Radio 106.5 FM (forwardradio.org) every Monday at 7:30 pm, Tuesday at 11:30 am, and Wednesday at 7:30 am. Visit our Facebook page for links to the articles discussed in this episode: https://www.facebook.com/BenchTalkRadio

Want to drop 8-12 lbs before summer without crash dieting or losing muscle? Join the Get Lean in 45 Days Workshop on January 20th. Includes replay, fat loss workout program, custom macros, and complete 45-day protocol.—Are you lifting weights, tracking macros, and still stuck with stubborn fat? What if your labs look “normal” but your metabolism feels broken?Body recomp is supposed to feel simpler when you train hard and eat well, yet many people chasing weight loss and muscle building feel stuck. I brought on Dr. Amie Hornaman, known as the Thyroid Fixer, to challenge the way we think about metabolism, hormone health, and strength training. We explored T2, a lesser-known thyroid hormone that acts directly at the mitochondria to help burn fat, boost energy, and protect lean mass.This conversation matters if you care about nutrition and fitness, longevity, and strength training over 40, especially for women's fitness and anyone frustrated by slow progress despite doing “everything right.” We connected evidence-based fitness, evidence-based nutrition, and smart supplementation, without hype or shortcuts.Today, you'll learn all about:0:00 – Why metabolism feels broken4:20 – The forgotten thyroid hormone9:45 – T2 vs T3 and T415:30 – Fat loss without muscle loss22:10 – Mitochondria and metabolism28:40 – Appetite vs energy expenditure35:55 – Strength training and thyroid health44:30 – Hashimoto's and lab myths52:20 – Practical next stepsEpisode resources:Thyroid Fixxr T2 Supplement - get 10% off with code WITSThe Thyroid Fixer Podcast - follow to get Philip's episode soon!Free 7-Day Thyroid Healing KickstarterJust Fix Your THYROID Facebook GroupWebsite: dramie.com Support the show

Are you exhausted all the time? In this solo episode, Darin breaks down why so many people feel chronically exhausted despite eating clean, exercising, and "doing everything right." He explains how modern life disrupts mitochondrial function, circadian rhythm, stress signaling, and nutrient availability, and why fatigue is not a personal failure, but a biological signal. This episode offers a grounded, practical roadmap to restoring energy by realigning your environment, habits, and daily rhythms with how the body is actually designed to function.     What You'll Learn in This Episode: Why chronic fatigue is exploding—even among healthy, active people How mitochondria do far more than "make energy" The role of circadian rhythm, light exposure, and timing in energy production Why stress, overtraining, and modern lifestyles drain cellular energy How emotional suppression and unexpressed stress affect vitality The difference between forcing energy and allowing energy Simple daily practices that support mitochondrial repair How breathwork, stillness, and social connection restore resilience Why nutrition alone isn't enough without rhythm and recovery How to realign your biology with the modern world     Timecodes 00:00:00 – Welcome to SuperLife and the intention behind this episode 00:00:32 – Sponsor: TheraSage and natural frequency-based healing 00:02:10 – Happy New Year + why this conversation matters now 00:02:37 – Are you exhausted even though you're "doing everything right"? 00:03:26 – The modern energy crisis and rising chronic fatigue 00:04:12 – Why surface-level health advice no longer works 00:04:27 – Mitochondria: more than energy factories 00:04:59 – Circadian misalignment, EMFs, and modern stressors 00:05:36 – Overtraining, stress load, and lack of recovery 00:06:00 – Fatigue as a signal, not a lack of discipline 00:06:18 – How artificial light disrupts internal clocks 00:07:25 – Discipline as alignment with natural rhythms 00:07:36 – Emotional release, primal expression, and energy recovery 00:08:47 – Why "why am I tired all the time?" is exploding online 00:09:24 – The mitochondria as environmental sensors 00:10:06 – Stress signaling, thoughts, and cellular energy flow 00:11:18 – Breathwork and slowing the nervous system 00:12:24 – Social connection and low-stress signaling 00:13:02 – Sponsor: Bite toothpaste and eliminating plastic exposure 00:15:19 – Morning sunlight and circadian priming 00:15:52 – Reducing artificial light at night 00:16:15 – Nutrients that support mitochondrial function 00:17:29 – Sleep timing, consistency, and repair 00:18:20 – Evening routines and melatonin protection 00:19:46 – Small daily steps compound into real energy 00:20:17 – Antioxidants, inflammation, and recovery 00:20:49 – Training smarter, not harder 00:21:31 – Breathwork, sauna, and recovery rituals 00:22:26 – Nutrition, protein, and polyphenols 00:24:37 – Five daily energy takeaways 00:25:24 – Energy is permitted, not forced 00:26:03 – Listening to the body and closing reflections 00:26:49 – SuperLife Patreon and community support     Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien     Thank You to Our Sponsors: Therasage: Go to www.therasage.com and use code DARIN at checkout for 15% off Bite Toothpaste: Go to trybite.com/DARIN20 or use code DARIN20 for 20% off your first order.     Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences     Key Takeaway "Fatigue isn't failure. It's feedback. When your environment, timing, and signals align, your biology remembers how to thrive."     Bibliography/Sources: Ames, B. N. (2006). Low micronutrient intake may accelerate the degenerative diseases of aging through allocation triage. Proceedings of the National Academy of Sciences, 103(47), 17589–17594. https://doi.org/10.1073/pnas.0608757103 Bass, J., & Takahashi, J. S. (2010). Circadian integration of metabolism and energetics. Science, 330(6009), 1349–1354. https://doi.org/10.1126/science.1195668 Gooley, J. J., Chamberlain, K., Smith, K. A., Khalsa, S. B., Rajaratnam, S. M., Van Reen, E., Zeitzer, J. M., Czeisler, C. A., & Lockley, S. W. (2011). Exposure to room light before bedtime suppresses melatonin onset and shortens melatonin duration in humans. The Journal of Clinical Endocrinology & Metabolism, 96(3), E463–E472. https://doi.org/10.1210/jc.2010-2098 Kreher, J. B., & Schwartz, J. B. (2012). Overtraining syndrome: A practical guide. Sports Health, 4(2), 128–138. https://doi.org/10.1177/1941738111434406 Meeusen, R., Duclos, M., Foster, C., Fry, A., Gleeson, M., Nieman, D., Raglin, J., Rietjens, G., Steinacker, J., & Urhausen, A. (2013). Prevention, diagnosis, and treatment of the overtraining syndrome: Joint consensus statement of the European College of Sport Science and the American College of Sports Medicine. European Journal of Sport Science, 13(1), 1–24. https://doi.org/10.1080/17461391.2012.730061 Panda, S. (2016). Circadian physiology of metabolism. Cell Metabolism, 23(6), 1152–1163. https://doi.org/10.1016/j.cmet.2016.06.005 Picard, M., Juster, R. P., & McEwen, B. S. (2014). Mitochondrial allostatic load: Putting the 'gluc' back in glucocorticoids. Nature Reviews Endocrinology, 10(5), 303–310. https://doi.org/10.1038/nrendo.2014.22 Picard, M., & McEwen, B. S. (2018). Psychological stress and mitochondria: A systematic review. Psychosomatic Medicine, 80(2), 126–140. https://doi.org/10.1097/PSY.0000000000000544 Picard, M., McElroy, G. S., & Turnbull, D. M. (2015). Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory, and transcriptional responses to acute psychological stress. Proceedings of the National Academy of Sciences, 112(48), 14920–14925. https://doi.org/10.1073/pnas.1518223112 Reiter, R. J., Rosales-Corral, S., Tan, D. X., Acuna-Castroviejo, D., Qin, L., Yang, S. F., & Xu, K. (2017). Melatonin as a mitochondria-targeted antioxidant: One of evolution's best inventions? Journal of Pineal Research, 62(1), e12394. https://doi.org/10.1111/jpi.12394 Scheer, F. A., Hilton, M. F., Mantzoros, C. S., & Shea, S. A. (2009). Adverse metabolic and cardiovascular consequences of circadian misalignment. Proceedings of the National Academy of Sciences, 106(11), 4453–4458. https://doi.org/10.1073/pnas.0808180106 Straub, R. H. (2017). The brain and immune system prompt energy shortage in chronic inflammation and ageing. Nature Reviews Rheumatology, 13(2), 74–79. https://doi.org/10.1038/nrrheum.2016.213 World Health Organization. (n.d.). Micronutrient deficiencies. World Health Organization. https://www.who.int/health-topics/micronutrients

In this episode, Dr. Datis Kharrazian explores longevity medicine and the hallmarks of aging and disease. How do early signs of loss of resilience—like cognitive decline or changes in physical appearance—offer clues about our biological age? What can cutting-edge studies, such as the Dunedin Longitudinal Study, teach us about predicting poor aging trajectories and preventing chronic diseases like cardiovascular issues and cancer, before they silently take hold?Dr. Kharrazian uncovers the mechanisms underlying tissue degeneration, explores why resilience is central to healthy aging, and explains how functional medicine clinicians can use biomarkers and in-depth assessments to help shift morbidity later in life. Whether you're a healthcare practitioner, a nutrition enthusiast, or facing chronic health challenges, this episode bridges the gap between complex science and actionable steps you can implement right now.Learn functional longevity strategies from Dr. Datis Kharrazian. Discover how to use personalized nutrition, diet, and lifestyle approaches to optimize healthspan. Enroll in the Longevity Mastery Program at: https://pages.kharrazianinstitute.com/longevityFor patient-oriented functional medicine courses, visit https://drknews.com/online-courses/For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/00:00 "Longevity, Wellness, and Disease"03:51 "Pace and Markers of Aging"09:02 "Aging Mechanisms and Disease Links"13:33 Aging, Resilience, and Clinical Outcomes14:52 "Hallmarks of Aging Explained"20:11 "Aging Tissues and Inflammation"22:18 Mitochondria, Aging, and Vascular Health25:59 Cancer Warning Signs32:21 "Aging's Role in Cancer Progression"33:13 "Functional Health Solutions Podcast"Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

We're back with another episode in a series of highly vetted companies that I love sharing with my community. Today, I'm joined by Forrest Smith, the co-founder and CEO of Kineon. A dynamic entrepreneur with an infectious enthusiasm for his work, Forrest reads and writes fluent Chinese, lives in Mexico, and brings over 20 years of experience building and scaling successful startups. His work at Kineon reflects his optimism and innovative approach in the field of health and wellness technology. In our conversation, we explore what red light therapy (photobiomodulation) is and its cellular and mitochondrial effects. We unpack the benefits of methylene blue, the impact of photobiomodulation on joint pain and thyroid health, and specific contraindications. We also discuss red light therapy and the gut hormone access, peptides, recovery toolkits, and female-centric research related to infertility, PCOS, endometriosis, thyroid health, and more. This is one of those conversations you will likely want to listen to more than once. Be sure to check the show notes for a special offer from Kineon, exclusively for my listeners. IN THIS EPISODE, YOU WILL LEARN: What is red light therapy? How red light therapy supports the body at the cellular level, particularly during the aging process How methylene blue enhances the effects of red light therapy The value of photobiomodulation for treating chronically inflamed joints and muscle tissue How local inflammation in the joints impacts gut health The benefits of red light therapy for female-specific pathologies, such as endometriosis, hypothyroidism, and dysmenorrhea The way that red light therapy works in combination with stem cell treatments, PRP, and extracorporeal shock wave therapy Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow  Cynthia's Menopause Gut Book is on presale now! Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Connect with Forrest Smith Kineon Kineon Labs on Instagram We're giving away TWO Kineon Move+ Pro devices (worth $499 each!) Want to enter? Leave a review of the Everyday Wellness podcast in English on Apple Podcasts or Spotify.  Take a screenshot of your review. Email the screenshot and one reason why you'd like to win to podcast@cynthiathurlow.com (You must live in the U.S. to enter.)

Send us a textCellular metabolism, mitochondrial health, and the roles of diet and environment in metabolic health, fetal & child development, and Alzheimer's.TOPICS DISCUSSED:Cellular growth vs. burning: Cells alternate between growing (using glucose for building blocks in low-oxygen environments) and burning (generating ATP in mitochondria with oxygen); dysregulation leads to metabolic issues.Key regulatory enzymes: PI3 kinase imports glucose, AMP kinase builds mitochondria, and mTOR drives cell division; their synchronization determines healthy modes, while desynchronization causes diseases.Fructose as a dose-dependent mitochondrial toxin: High fructose intake inhibits AMP kinase, reducing mitochondrial function and diverting energy to fat storage; it is dose-dependent, like alcohol, and unnecessary in the diet.Obesogens & endocrine disruptors: Chemicals like tributyltin (TBT) alter gene expression across generations, promoting obesity unrelated to calories; modern exposures increase reactive oxygen species (ROS), burdening cells.Fetal & neonatal development: Maternal diet, especially high sugar or formula feeding, can cause neonatal obesity and fatty liver; breastfeeding supports proper jaw development and oxygen intake.Brain metabolism & Alzheimer's: The brain's high energy needs make it vulnerable to mitochondrial issues and ROS; energy deficits from diet, stress, and toxins lead to synapse loss and inflammation, treatable via prevention.ROS & health: Mitochondria produce ROS as a byproduct of ATP generation; excess from diet or environment causes damage, but antioxidants and lifestyle can mitigate risks.PRACTICAL TAKEAWAYS:Limit added sugars in your diet to reduce mitochondrial stress and ROS, focusing on whole foods over ultra-processed items for better metabolic health.Prioritize breastfeeding for infants when possible to support proper physical development and reduce future metabolic risks.Incorporate regular exercise and social activities to manage stress and boost brain-protective factors like BDNF, aiding neurodegeneration prevention.Get adequate sleep to regulate cortisol and maintain cellular energy balance, helping prevent brain fog and chronic diseases.ABOUT THE GUEST: Robert Lustig, MD is a pediatric endocrinologist and Professor Emeritus at the University of California, San Francisco, with a background in neuroendocrinology and obesity research.*Not medical advice.Support the showAffiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts

In this expansive and deeply honest conversation, Darin sits down with Gregory Schwartz for a wide-ranging exploration of awakening, ecology, food systems, energy, consciousness, and what it truly means to live in right relationship with the planet and ourselves. What begins as a conversation about athletic identity and environmental travel unfolds into a profound dialogue on political ecology, spiritual awakening, mitochondrial intelligence, community-scale solutions, and the collapse of outdated belief systems. This episode bridges the scientific, the spiritual, and the deeply human—offering a grounded yet visionary roadmap for creating a future where health, sovereignty, and connection replace extraction, disconnection, and burnout.     What You'll Learn in This Episode How early athletic identity, injury, and discipline shaped Greg's lifelong path Why travel and "ground-truthing" reality changes how we see the world The concept of the "Planet Doctor" and speaking on behalf of Earth Why data alone doesn't change behavior—and why the heart must lead How food systems, soil health, and gut health are inseparably linked The real reasons environmental solutions stall despite available money and technology Why community-scale action is the missing link between individual and government change How regenerative food systems ripple into health, ecology, and social cohesion The dangers of hyper-productivity and the loss of rest, recovery, and contemplation Why mitochondria are not just powerhouses—but listeners and conductors of energy What spiritual awakening actually feels like—and why it can be destabilizing The collapse of identity as a necessary step toward integration The difference between being a messenger and being the message How awakenings mature from chaos into discipline, embodiment, and service Why optimism comes from living examples, not abstract ideology How small, aligned actions create resonance fields that attract new realities     Timecodes 00:00 – Athletic roots, injury, and the pivot into physiology & nutrition 03:00 – Travel, environmental exposure, and seeing reality beyond data 07:00 – Political ecology, capitalism, and the illusion of separation from nature 12:30 – Food systems, soil health, and gut microbiome parallels 16:00 – Regenerative agriculture, working with farmers, and nuance over dogma 20:00 – Community-scale solutions: food, energy, microgrids, and localization 24:00 – Burnout culture, productivity addiction, and missing rest cycles 27:00 – Mitochondria, flow state, and the intelligence of the cell 30:00 – Spiritual awakening: lightning bolts, breakdowns, and integration 35:00 – Heaven, hell, and altered states as present-moment realities 39:00 – Discipline vs. chaos: maturing the awakening process 44:00 – Being the message vs. delivering the message 49:00 – Embodiment, purpose, and integrating spirituality into real life 55:00 – System collapse, courage, and rebuilding new realities 01:00:00 – Hope, optimism, and why examples matter more than arguments 01:05:00 – Creating resonance through aligned action and community     Find More From Gregory Schwartz Political ecology research and teaching Environmental systems, food sovereignty, and regenerative frameworks Community-scale energy and food solutions Writing and speaking on consciousness, awakening, and integration     Thank You to Our Sponsors Truniagen: Go to www.truniagen.com and use code DARIN20 at checkout for 20% off Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout.     Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien     Find More from Gregory Schwartz Website: theplanetdoctor.com Instagram: @theplanetdoctor Try Greg's Free Masterclass by signing up here!     Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences     Key Takeaway "The systems don't change because we lack solutions—they don't change because we haven't changed our relationship to ourselves, to nature, and to each other. When that shifts, everything else follows."  

Episode 210: Heat Stroke BasicsWritten by Jacob Dunn, MS4, American University of the Caribbean. Edits and comments by Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice. Definition:Heat stroke represents the most severe form of heat-related illness, characterized by a core body temperature exceeding 40°C (104°F) accompanied by central nervous system (CNS) dysfunction. Arreaza: Key element is the body temperature and altered mental status. Jacob: This life-threatening condition arises from the body's failure to dissipate heat effectively, often in the context of excessive environmental heat load or strenuous physical activity. Arreaza: You mentioned, it is a spectrum. What is the difference between heat exhaustion and heat stroke? Jacob: Unlike milder heat illnesses such as heat exhaustion, heat stroke involves multisystem organ dysfunction driven by direct thermal injury, systemic inflammation, and cytokine release. You can think of it as the body's thermostat breaking under extreme stress — leading to rapid, cascading failures if not addressed immediately. Arreaza: Tell us what you found out about the pathophysiology of heat stroke?Jacob: Pathophysiology: Under normal conditions, the body keeps its core temperature tightly controlled through sweating, vasodilation of skin blood vessels, and behavioral responses like seeking shade or drinking water. But in extreme heat or prolonged exertion, those mechanisms get overwhelmed.Once core temperature rises above about 40°C (104°F), the hypothalamus—the brain's thermostat—can't keep up. The body shifts from controlled thermoregulation to uncontrolled, passive heating. Heat stroke isn't just someone getting too hot—it's a full-blown failure of the body's heat-regulating system. Arreaza: So, it's interesting. the cell functions get affected at this point, several dangerous processes start happening at the same time.Jacob: Yes: Cellular Heat InjuryHigh temperatures disrupt proteins, enzymes, and cell membranes. Mitochondria start to fail, ATP production drops, and cells become leaky. This leads to direct tissue injury in vital organs like the brain, liver, kidneys, and heart.Arreaza: Yikes. Cytokines play a big role in the pathophysiology of heat stroke too. Jacob: Systemic Inflammatory ResponseHeat damages the gut barrier, allowing endotoxins to enter the bloodstream. This triggers a massive cytokine release—similar to sepsis. The result is widespread inflammation, endothelial injury, and microvascular collapse.Arreaza: What other systems are affected?Coagulation AbnormalitiesEndothelial damage activates the clotting cascade. Patients may develop a DIC-like picture: microthrombi forming in some areas while clotting factors get consumed in others. This contributes to organ dysfunction and bleeding.Circulatory CollapseAs the body shunts blood to the skin for cooling, perfusion to vital organs drops. Combine that with dehydration from sweating and fluid loss, and you get hypotension, decreased cardiac output, and worsening ischemia.Arreaza: And one of the key features is neurologic dysfunction.Jacob: Neurologic DysfunctionThe brain is extremely sensitive to heat. Encephalopathy, confusion, seizures, and coma occur because neurons malfunction at high temperatures. This is why altered mental status is the hallmark of true heat stroke.Arreaza: Cell injury, inflammation, coagulopathy, circulatory collapse and neurologic dysfunction. Jacob: Ultimately, heat stroke is a multisystem catastrophic event—a combination of thermal injury, inflammatory storm, coagulopathy, and circulatory collapse. Without rapid cooling and aggressive supportive care, these processes spiral into irreversible organ failure.Background and Types:Arreaza: Heat stroke is part of a spectrum of heat-related disorders—it is a true medical emergency. Mortality rate reaches 30%, even with optimal treatment. This mortality correlates directly with the duration of core hyperthermia. I'm reminded of the first time I heard about heat stroke in a baby who was left inside a car in the summer 2005. Jacob: There are two primary types: -nonexertional (classic) heat stroke, which develops insidiously over days and predominantly affects vulnerable populations like children, the elderly, and those with chronic illnesses during heat waves; -exertional heat stroke, which strikes rapidly in young, otherwise healthy individuals, often during intense exercise in hot, humid conditions. Arreaza: In our community, farm workers are especially at risk of heat stroke, but any person living in the Central Valley is basically at risk.Jacob: Risk factors amplify vulnerability across both types, including dehydration, cardiovascular disease, medications that impair sweating (e.g., anticholinergics), and acclimatization deficits. Notably, anhidrosis (lack of sweating) is common but not required for diagnosis. Hot, dry skin can signal the shift from heat exhaustion to stroke. Arreaza: What other conditions look like heat stroke?Differential Diagnosis:Jacob: Presenting with altered mental status and hyperthermia, heat stroke demands a broad differential to avoid missing mimics. -Environmental: heat exhaustion, syncope, or cramps. -Infectious etiologies like sepsis or meningitis must be ruled out. -Endocrine emergencies such as thyroid storm, pheochromocytoma, or diabetic ketoacidosis (DKA) can overlap. -Neurologic insults include cerebrovascular accident (CVA), hypothalamic lesions (bleeding or infarct), or status epilepticus. -Toxicologic culprits are plentiful—sympathomimetic or anticholinergic toxidromes, salicylate poisoning, serotonin syndrome, malignant hyperthermia, neuroleptic malignant syndrome (NMS), or even alcohol/benzodiazepine withdrawal. When it comes to differentials, it is always best to cast a wide net and think about what we could be missing if this is not heat stroke. Arreaza: Let's say we have a patient with hyperthermia and we have to assess him in the ER. What should we do to diagnose it?Jacob: Workup:Diagnosis is primarily clinical, hinging on documented hyperthermia (>40°C) plus CNS changes (e.g., confusion, delirium, seizures, coma) in a hot environment. Arreaza: No single lab confirms it, but targeted testing allows us to detect complications and rule out alternative diagnosis. Jacob: -Start with ECG to assess for dysrhythmias or ischemic changes (sinus tachycardia is classic; ST depressions or T-wave inversions may hint at myocardial strain). -Labs include complete blood count (CBC), comprehensive metabolic panel (electrolytes, renal function, liver enzymes), glucose, arterial blood gas, lactate (elevated in shock), coagulation studies (for disseminated intravascular coagulation, or DIC), creatine kinase (CK) and myoglobin (for rhabdomyolysis), and urinalysis. Toxicology screen if history suggests. Arreaza: I can imagine doing all this while trying to cool down the patient. What about imaging?-Imaging: chest X-ray for pulmonary issues, non-contrast head CT if neurologic concerns suggest edema or bleed (consider lumbar puncture if infection suspected). It is important to note that continuous core temperature monitoring—via rectal, esophageal, or bladder probe—is essential, not just peripheral skin checks. Arreaza: TreatmentManagement:Time is tissue here—initiate cooling en route, if possible, as delays skyrocket morbidity. ABCs first: secure airway (intubate if needed, favoring rocuronium over succinylcholine to avoid hyperkalemia risk), support breathing, and stabilize circulation. -Remove the patient from the heat source, strip clothing, and launch aggressive cooling to target 38-39°C (102-102°F) before halting to prevent rebound hypothermia. -For exertional cases, ice-water immersion reigns supreme—it's the fastest method, with immersion in cold water resulting in near-100% survival if started within 30 minutes. -Nonexertional benefits from evaporative cooling: mist with tepid water (15-25°C) plus fans for convective airflow. -Adjuncts include ice packs to neck, axillae, and groin; -room-temperature IV fluids (avoid cold initially to prevent shivering); -refractory cases, invasive options like peritoneal lavage, endovascular cooling catheters, or even ECMO. -Fluid resuscitation with lactated Ringer's or normal saline (250-500 mL boluses) protects kidneys and counters rhabdomyolysis—aim for urine output of 2-3 mL/kg/hour. Arreaza: What about medications?Jacob: Benzodiazepines (e.g., lorazepam) control agitation, seizures, or shivering; propofol or fentanyl if intubated. Avoid antipyretics like acetaminophen. For intubation, etomidate or ketamine as induction agents. Hypotension often resolves with cooling and fluids; if not, use dopamine or dobutamine over norepinephrine to avoid vasoconstriction. Jacob: What IV fluid is recommended/best for patients with heat stroke?Both lactated Ringer's solution and normal saline are recommended as initial IV fluids for rehydration, but balanced crystalloids such as LR are increasingly favored due to their lower risk of hyperchloremic metabolic acidosis and AKI. However, direct evidence comparing the two specifically in the setting of heat stroke is limited. Arreaza: Are cold IV fluids better/preferred over room temperature fluids?Cold IV fluids are recommended as an adjunctive therapy to help lower core temperature in heat stroke, but they should not delay or replace primary cooling methods such as cold-water immersion. Cold IV fluids can decrease core temperature more rapidly than room temperature fluids. For example, 30mL/kg bolus of chilled isotonic fluids at 4 degrees Celsius over 30 minutes can decrease core temperature by about 1 degree Celsius, compared to 0.5 degree Celsius with room temperature fluids. Arreaza: Getting cold IV sounds uncomfortable but necessary for those patients. Our favorite topic.Screening and Prevention:-Heat stroke prevention focuses on public health and individual awareness rather than routine testing. -High-risk groups—elderly, children, athletes, laborers, or those on impairing meds—should acclimatize gradually (7-14 days), hydrate preemptively (electrolyte solutions over plain water), and monitor temperature in exertional settings. -Communities during heat waves need cooling centers and alerts. -For clinicians, educate patients with CVD or obesity about early signs like dizziness or nausea. -No formal "screening" exists, but vigilance in EDs during summer surges saves lives. -Arreaza: I think awareness is a key element in prevention, so education of the public through traditional media like TV, and even social media can contribute to the prevention of this catastrophic condition.Jacob: Ya so heat stroke is something that should be on every physician's radar in the central valley especially in the summer time given the hot temperatures. Rapid recognition is key. Arreaza: Thanks, Jacob for this topic, and until next time, this is Dr. Arreaza, signing off.Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! References:Gaudio FG, Grissom CK. Cooling Methods in Heat Stroke. J Emerg Med. 2016 Apr;50(4):607-16. doi: 10.1016/j.jemermed.2015.09.014. Epub 2015 Oct 31. PMID: 26525947. https://pubmed.ncbi.nlm.nih.gov/26525947/.Platt, M. A., & LoVecchio, F. (n.d.). Nonexertional classic heat stroke in adults. In UpToDate. Retrieved September 7, 2025, from https://www.uptodate.com/contents/nonexertional-classic-heat-stroke-in-adults. (Key addition: Emphasizes insidious onset in at-risk populations and the role of urban heat islands in exacerbating classic cases.) Heat Stroke. WikEM. Retrieved December 3, 2025, from https://wikem.org/wiki/Heat_stroke. (Key additions: Details on cooling rates for immersion therapy, confirmation that anhidrosis is not diagnostic, and fluid titration to urine output for rhabdomyolysis prevention.)Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/. 

Send us a textMitochondrial dysfunction affects overall energy production and is linked to chronic conditions including fatigue, brain fog, and inflammatory disorders. We explore how to support cellular energy through nutrition, lifestyle, and mindset transformation.• Mitochondria are the cell's powerhouse, affecting metabolism, oxidative stress, and cellular signaling• Poor diet, medications, toxins, chronic stress, and inadequate exercise can disrupt mitochondrial function• Key supplements for energy support include CoQ10, alpha-lipoic acid, acetyl-L-carnitine, magnesium, and B vitamins• Lifestyle interventions like intermittent fasting, red light therapy, grounding, and quality sleep improve energy production• Heavy metals including lead, arsenic, and mercury can directly poison mitochondria and decrease energy• Energy production requires proper macronutrients (carbs, fats, proteins) and micronutrients (vitamins, minerals, cofactors)• The "10 A's of Transformation" provide a holistic framework for energy enhancement: Awareness, Action, Alignment, Accountability, Acceptance, Authenticity, Attention, Adaptability, Appreciation, and Abundance Support the show Sponsor Affiliates Empowering Your Health https://www.atecam.com/ Get YOUR Own Joburg Protein Snacks Discount Code: Damaris15 Or Damaris18 Feeling need to Lose Weight & Become metabolically Healthy GET METABOLIC COURSE GLP 1 REseT This course is designed for individuals looking to optimize their metabolic health through integrative and functional medicine approaches. Whether you're on a GLP-1 medication or seeking natural ways to enhance your metabolic function, this course provides actionable steps, expert insights, and a personalized roadmap sustainable wellness. Are you feeling stressed, tired, or Metabolism imbalanced? Take advantage of our free mindful steps to help improve your well-being.ENJOY ONE OF our Books Mindful Ways Health Wealth & Life https://stan.store/Mindfullyintegrative Join Yearly membership ALL IN ONE FUNCTION HEALTH Ask Us for help...

Podcast Description: The Cellular Breakthrough That Changed How I See Chronic IllnessSchedule a Discovery Zoom call to see if we can help you!Welcome to today's episode with Doctor Hugh. In this podcast, I share a simple but powerful idea that has helped many of my clients heal faster than ever before.This is about cell energy, sunlight, and how your body makes power to heal.What This Episode Is AboutA cellular breakthrough that changed how I treat chronic illnessWhy many sick people are still not getting betterHow the body uses light like plants use sunlightWhy energy comes before detoxOne affordable tool that helps fragile and very sick people healWho This Episode Is ForIf you struggle with:FibromyalgiaBrain fogIBS or gut problemsDamage from antibioticsChronic fatigueTrouble thinking or memory lossThis episode is for you.The Big Idea: Your Body Uses LightPlants use sunlight to grow foodThis process is called photosynthesisYour body works in a similar waySpecial light waves help your cells make energyWhen you don't get enough of these light waves:Cells slow downMitochondria stop working wellHealing becomes very hardWhy Chronic Illness HappensMany sick people are low in healthy light exposureModern life keeps us indoorsYour cells become energy starvedLow energy leads to pain, inflammation, and diseaseWhy Infrared Light MattersMost sunlight energy is invisibleOnly a small part is visible lightInfrared light makes up over half of the sun's energyThis light goes deep into the bodyDeep light helps:Mitochondria make energyCells repair themselvesThe body heal without stressNot All Heat Is the SameThis is not about sweatingSick people should not push detoxThe goal is gentle energy supportThe wavelength does the workWhy I Recommend an Infrared Sauna BlanketSkin-to-skin contact gives deep penetrationWorks without extreme heatSafe for very fragile peopleAffordable and easy to use at homeKey benefits:Supports energy productionHelps cells heal naturallyNo harsh detox reactionsUnderstanding Infrared Light (Simple Version)Near infrared = closer to visible lightMid infrared = middle rangeFar infrared = deepest penetrationFar infrared goes deepest, reaching:CellsMitochondriaCell membranesThat's why it matters most for chronic illness.Why Deeper Is BetterDeeper light reaches energy factories in cellsEnergy leads to repairRepair leads to healingJust like sunlight feeds plants:Infrared light feeds your cellsReal ResultsSince focusing on energy first:Clients heal fasterProgress is smootherLess crashing and setbacksBetter long-term recoveryFinal MessageYou do not need to suffer.You need:The right energyThe right guidanceA plan made for your bodyNext StepsVisit my websiteSchedule a callGet a guided plan made just for youHealing

Dr. Lara Briden challenges everything you think you know about metabolism, revealing why energy—not weight—is the true marker of metabolic health. This conversation explores how modern life has pushed our physiology into states it was never designed for, and offers a compassionate, science-based approach to understanding your body as a logical system rather than a problem to fix.GUEST INFORMATION:Name: Dr. Lara BridenTitle/Credentials: Naturopathic doctor, author, former evolutionary biology researcher Background: Has peer-reviewed publications and thesis in evolutionary biology, specializes in women's health with focus on centering female physiology as normal mammalian function EPISODE HIGHLIGHTS:Evolutionary Biology FrameworkDr. Briden explains how her background in evolutionary biology informs her medical practice, viewing women's bodies as logical systems that make biological sense Menopause as Evolutionary AdvantageDiscussion of how menopause evolved as a survival advantage, with post-reproductive women being essential for family group survival Debunking the Willpower MythChallenges the narrative that metabolic issues are about eating too much and exercising too little The Asthma AnalogyExplains why telling people to "just lose weight" is like telling someone with asthma to "just breathe better" Environmental FactorsDetails how environmental toxins, gut microbiome changes, and epigenetics contribute to metabolic dysfunction across species and generations Energy as Metabolic MarkerExplains metabolic flexibility and how the body should preferentially burn fat in fasting states Blood Sugar CrashesDiscusses how insulin resistance often presents as reactive hypoglycemia rather than high blood sugar Seed Oils DiscussionDr. Briden shares her perspective on high-dose omega-6 oils as metabolically problematic signaling molecules Nervous System and MetabolismExplores how the autonomic nervous system significantly impacts insulin sensitivity and metabolic rate Key Metabolic NutrientsDiscuss essential nutrients for metabolic health: magnesium, taurine, choline, inositol, and glycine, historically obtained from organ meats Mitochondria as MastersFascinating discussion of mitochondria as dynamic cellular powerhouses affected by emotions and social activity Lab Testing SimplifiedProvides practical lab markers for insulin resistance: ALT levels, ALT to AST ratio, and triglycerides RESOURCES MENTIONED:Metabolism Repair For Women, by Dr. BridenPeriod Repair Manual (previous book) Potential upcoming cookbook collaboration KEY TAKEAWAYS:Metabolism problems often come before weight gain, not after—it's about insulin resistance first Energy levels and satiety between meals are better indicators of metabolic health than body weight Environmental factors including toxins, processed oils, and gut dysfunction are major contributors to metabolic issues The body has a complex system that can't be micromanaged—focus on removing obstacles and supporting overall health Simple lab tests (ALT, triglycerides) can reveal insulin resistance more effectively than complex testing Website: https://www.larabriden.com/CALL TO ACTION:Subscribe to the One Thing Podcast for more conversations that challenge conventional health wisdom and center biology over blame. Share this episode with someone who's been struggling with metabolic health issues—these insights could be exactly what they need to hear.

Have you ever said, "I just don't feel like myself anymore" — even though your labs look normal? In this episode of the Health Fix Podcast, Dr. Jannine Krause breaks down why inflammation starts in the brain, how it drives fatigue, brain fog, cravings, hormone imbalance, and accelerated aging — and why 2026 is the year to stop suppressing symptoms and start correcting root causes. Inflammation isn't just a body problem. It's a brain health issue first. Your brain uses 20% of your daily calories, and when inflammation is present, it shifts into defensive mode, not performance mode. That's when clarity disappears, energy crashes, and nothing feels like it's working anymore.

This solo masterclass on oxalates explains why many people who eat clean still struggle with joint pain, kidney stones, fatigue, brain fog, and chronic inflammation. You'll learn how oxalates behave very differently from other plant compounds like lectins, phytates, and salicylates. Unlike those compounds, oxalates physically bind minerals and form microscopic crystals that can lodge in tissues, damage mitochondria, and accumulate over time. This episode will change how you think about superfoods, clean eating, and long term human performance. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey walks you through the real science of oxalates using decades of self experimentation, functional medicine research, and hands on biohacking. As the founder of the biohacking movement, Dave has tested fasting, ketosis, carnivore strategies, supplements, nootropics, sleep optimization protocols, and metabolic interventions to uncover what actually improves resilience, neuroplasticity, and mitochondrial function without unnecessary damage. In this masterclass, you'll learn why oxalates cause problems even when digestion seems fine, why symptoms can show up in joints, kidneys, nerves, skin, and old injuries, and why reducing oxalates too fast can make you feel worse before you feel better. Dave explains oxalate dumping, candida driven oxalate overload, microbiome interactions, and why foods like spinach, almonds, cacao, and green smoothies often backfire over time. He also shares practical ways to lower your oxalate load safely, support mineral balance, and protect your metabolism and brain using a Smarter Not Harder approach. This episode is for you if you eat “healthy” but still feel off, deal with unexplained pain or inflammation, or want to improve longevity, brain optimization, sleep, and human performance without extreme restriction. You'll Learn: • Why oxalates are different from lectins, phytates, and other plant toxins • How oxalates drain minerals and damage mitochondria • What oxalate dumping feels like and how to avoid it • Which superfoods cause the biggest problems and what to replace them with • How hydration, minerals, and supplements affect oxalate clearance • Why oxalates accelerate aging and tissue stiffness over time • Practical biohacking strategies to protect longevity and human performance Thank you to our sponsors! -ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. -Branch Basics | Get 15% off Branch Basics with the code DAVE15 at https://branchbasics.com/DAVE15. -BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 to save 20% off your first order of PerfectAmino. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: oxalates, oxalic acid, biohacking oxalates, oxalate dumping, plant toxins explained, lectins vs oxalates, phytates and mineral absorption, anti-nutrients, superfoods controversy, clean eating problems, kidney stones oxalates, joint pain inflammation, mineral depletion, calcium oxalate crystals, metabolism dysfunction, brain fog causes, neuroplasticity and inflammation, longevity nutrition, anti-aging nutrition, functional medicine oxalates, supplements for oxalates, hydration and kidney health, urinary pH balance, candida and oxalates, microbiome and oxalates, fasting and oxalates, ketosis and oxalates, carnivore diet transition, human performance nutrition, sleep optimization inflammation, nootropics and brain optimization, Dave Asprey oxalates Resources: • Join Our New Low-Oxalate Challenge! https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 – Trailer 1:25 – Introduction 3:18 – What Are Oxalates 5:40 – Oxalates vs Other Plant Toxins 7:18 – Oxalate Sources and Chemistry 9:17 – Kidney Stones and Crystal Formation 10:19 – Oxalate Dumping Explained 12:03 – System Level Effects 14:54 – Inflammation, Mitochondria, and Aging 16:56 – Who Should Pay Attention 19:32 – High Oxalate Foods 24:56 – Smart Food Swaps 27:22 – Exercise and Hydration 29:07 – Clearing Oxalates Safely 31:01 – Summary and Key Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This week I interviewed the Founder & CEO of Touchstone Essentials - Eddie Stone! Eddie's background working directly with everyday people on practical detox solutions, combined with his experience leading one of the most trusted clean supplement brands, gives him a unique perspective on the real-world challenges people face when trying to improve their health. We discussed the importance of sourcing when it comes to ingredients for health and wellness products along with:- Supporting Detox for your Cells- Power of Zeolites- How Environmental Factors affect your Healthand his one tip to get your body back to what it once was!Product Special: https://getleaneatclean.thegoodinside.com/special-offer-telo-vital-lp-------FREE Nutrition Cheatsheets:https://brian-getleaneatclean.beehiiv.com/subscribeClick to book a FREE 15 minute consult with Brian:https://calendly.com/bdgryn/15min------------Interested in Upgrading your Mitochondria, Improving Energy and Sleep! Check out Troscriptions: https://bit.ly/4ik5kK5Use Discount Code for 10% OFF: EATCLEAN----Watch Get Lean Eat Clean podcast video episodes on YouTube!YouTube.com/@briangryn3680----B.rad Whey Protein Isolate Superfuel:The Best Protein on The Planet! Available in Two Delicious Flavors: Vanilla Bean and Cocoa BeanUse Coupon Code glec10off for 10% off your order!https://a.co/d/731gssV----My favorite health bars with clean ingredients!https://www.eatprima.com/BRIAN6816310% OFF with this link!

In this solo episode of The SuperLife Podcast, Darin Olien dives deep into the true biology of energy—not motivation, not stimulants, not willpower, but the mitochondria themselves. Inspired by a groundbreaking conversation between Dr. Andrew Huberman and Dr. Martin Picard, Darin reframes energy as an emergent property of how we live, not just what we eat or how much we sleep. This episode explores how mitochondria act as signal translators, listening to your food, stress, sleep, movement, emotions, purpose, and environment—and turning those signals into either vitality or depletion. Darin connects cutting-edge mitochondrial science with real-world practices around recovery, meaningful stress, consistency, connection, and alignment, showing how true longevity and resilience are built at the cellular level.     What You'll Learn in This Episode 00:00  – Welcome to SuperLife & the mission of sovereignty and vitality 00:32 – Thera Sage sponsor: family-built healing tech & red light 02:10 – Why this episode is different: diving into cellular energy 02:42 – Inspiration from Huberman & Picard's mitochondria conversation 03:11 – Rethinking mitochondria: not just ATP, but information processors 04:03 – Energy as potential for change, not calories or fuel 04:39 – How thoughts, emotions, food, and stress shape energy 05:05 – Energy is dynamic, adaptive, and responsive to how you live 06:02 – Mitochondria as signal integrators: sleep, hormones, purpose, connection 06:50 – Mitochondria as antennas, not factories 07:16 – Translating life experience into biological energy 08:09 – Why we don't feel "energy," we feel energy flow 08:53 – Flow states, purpose, and why passion creates vitality 09:32 – Different organs, different mitochondrial roles 10:26 – Why energy optimization is not one-size-fits-all 10:49 – Energy resistance: the hidden cause of fatigue and burnout 11:47 – Chronic stress, poor sleep, and ultra-processed food as energy blockers 12:12 – Why recovery is non-negotiable for longevity 12:20 – Caldera Lab sponsor: clean, performance-driven skincare 14:20 – The danger of constant output without recovery 14:45 – Sleep as a mitochondrial reset and repair system 15:40 – Exercise, adaptation, and why recovery completes the signal 16:22 – Intentional stress vs. chronic stress 17:29 – Food as information, not just fuel 18:05 – Time-restricted eating, fresh food, and metabolic signaling 18:27 – Meaning, purpose, and emotional states as cellular inputs 19:23 – Mitochondria, aging, and the potential reversibility of decline 20:06 – SuperLife framework: alignment over optimization 20:37 – Consistency beats intensity at the cellular level 21:19 – Stable rhythms: sleep, nourishment, hydration, movement 21:45 – Stillness, meditation, and parasympathetic repair 22:35 – Growth requires both resistance and recovery 24:44 – Connection, community, and loneliness as biological signals 25:27 – Eliminating fatal conveniences to restore vitality 26:02 – Your mitochondria are listening—change the signals 26:21 – Honoring Huberman & Picard's contribution to human health 27:12 – Energy flow as the foundation of a SuperLife 28:11 – Closing reflections and invitation to apply this work     Thank You to Our Sponsors Therasage: Go to www.therasage.com and use code DARIN at checkout for 15% off Caldera Lab: Experience the clinically proven benefits of Caldera Lab's clean skincare regimen and enjoy 20% off your order by visiting calderalab.com/darin and using code DARIN at checkout.     Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien     Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences     Key Takeaway "Your mitochondria are not broken. They are responding perfectly to the signals you give them. Change the signals, and your energy, resilience, and life will follow."     Bibliography & Sources Here is the bibliography based on the sources referenced in the document, formatted with direct links to the scientific papers, books, and the podcast episode. Primary Source Material Huberman, A. (Host). (2025, December 15). Improve Energy & Longevity by Optimizing Mitochondria with Dr. Martin Picard [Audio/Video podcast]. Huberman Lab. Link to Episode Picard Lab. Mitochondrial Psychobiology Group. Columbia University Irving Medical Center. Link to Lab Website Key Scientific Literature & Books Hood, D. A., Memme, J. M., Oliveira, A. N., & Triolo, M. (2019). Exercise and Mitochondrial Biogenesis. Physiological Reviews, 99(1), 669–715. Read Study Lane, N. (2015). The Vital Question: Energy, Evolution, and the Origins of Complex Life. W.W. Norton & Company. Book Link López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013). The Hallmarks of Aging. Cell, 153(6), 1194–1217. Read Study Mattson, M. P., Moehl, K., Ghena, N., Schmaedick, M., & Cheng, A. (2018). Intermittent Metabolic Switching, Neuroplasticity and Brain Health. Nature Reviews Neuroscience, 19, 63–80. Read Study Picard, M., & McEwen, B. S. (2018). Psychological Stress and Mitochondria: A Systematic Review. Psychosomatic Medicine, 80(2), 126–140. Read Study Picard, M., & Shirihai, O. S. (2022). Mitochondrial Psychobiology: Foundations and Applications. Current Opinion in Behavioral Sciences, 43, 102–110. Read Study Speakman, J. R., & Selman, C. (2011). The Free-Radical Damage Theory: Accumulating Evidence Against a Simple Link. Trends in Ecology & Evolution, 26(1), 33–39. Read Study Wallace, D. C. (2015). Mitochondria and Cancer. Nature Reviews Cancer, 12, 685–698. (Note: Often referenced alongside his Annual Review of Genetics work on aging). Read Study

This episode originally aired as #432 on 5/22/24 and we are bringing it to you again! Parasite cleansing has become a hot topic in the natural health world, but it can feel a little overwhelming. Are you confused about where to start or how to do a cleanse yourself? On this episode of Vitality Radio, Jared demystifies the process by sharing his experience along with his wife's, and a thorough breakdown of the entire process, the products, and what to expect. You'll learn a couple of ways to approach parasite cleansing and which one might be right for you or your family, including kids.  If you never thought about parasites being a problem in America, think again! For a deeper understanding of why parasites are indeed a bigger problem than is understood by most, be sure to listen to Jared's interviews with Dr. Todd Watts and Dr. Jay Davidson - the founders of CellCore.Products:CellCore Para KitVitality Nutrition Parasite CleanseVital 5 Precision Probiotic Vital SporesMagnesium BisglycinateCellCore Bowel MoverLife Seasons Regulari-TRedmond RelyteTrace Minerals Endure Drops***Inquire for capsule-free protocol Additional Information:For information on coaching options and personalized support, please email jessica@vitalitynutrition.comVitality Wellness Community Detox & Support GroupVitality Radio Podcast Listener Community#359: Comprehensive Detoxification of Parasites, Lyme, and Other Toxins With Dr. Todd Watts of CellCore Biosciences#431: Are Parasites Part of Your Health Concerns? With Dr. Jay Davidson#385: Rebalancing and Healing the Body Through Functional Medicine Detoxification With Dr. Stephen Cabral#258: Your Magnesium User's Guide***Be sure to check out all of the Emotional Vitality Episodes, including Jen's Story mentioned in this showVisit the podcast website here: VitalityRadio.comYou can follow @vitalityradio and @vitalitynutritionbountiful on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Please also join us on the Dearly Discarded Podcast with Jared St. Clair.Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

In this episode, Dr. Jockers explores with Jason Prall how mitochondrial health and the gut microbiome are deeply connected, shaping energy, inflammation, and long-term resilience. You'll learn why mitochondria are far more than energy producers and how their communication drives whole-body health.   In this episode, you'll discover how the microbiome helps translate food into signals that influence mitochondrial function, metabolism, and cellular repair. Jason breaks down why diversity in the gut matters and how everyday choices quietly shape this internal dialogue.   In this episode, you'll hear practical insights on how sleep, light exposure, movement, fasting, and stress act as signals that either strengthen or weaken this mitochondrial–microbiome connection. The conversation leaves space to rethink how small lifestyle shifts can create powerful biological change.     In This Episode:  00:00 Introduction to Human and Mitochondrial DNA 04:06 Deep Dive into Mitochondria and Aging 14:01 Understanding the Gut Microbiome 25:38 Environmental Factors Affecting Health 29:19 Mindfulness and Detoxification 29:55 Impact of Thoughts on Health 31:06 Personalized Health Approaches 31:39 Universal Health Strategies 33:43 Importance of Sleep 37:19 Exercise and Movement 41:07 Fasting and Meal Timing 45:48 Stress and Recovery Balance 48:42 Final Thoughts and Resources     If you want practical, natural strategies to balance your hormones, heal your gut, boost your energy, and slow aging, don't miss The Dr. Josh Axe Show. Dr. Axe blends ancient wisdom with cutting-edge science and brings on world-class experts for unfiltered conversations you won't hear anywhere else. Transform your health from the inside out and subscribe to The Dr. Josh Axe Show, with new episodes every Monday and Thursday.   Support glowing skin, stronger joints, better digestion, and deeper sleep with Paleovalley's 100% Grass-Fed Bone Broth Protein. Unlike most brands that use hides and skins, Paleovalley slow-simmers real beef bones to extract collagen, glycine, and key amino acids that boost metabolism and reduce inflammation. Each scoop delivers 15 grams of collagen and the clinical dose of glycine for better sleep. Get 15% off at paleovalley.com/jockers.     "Every disease involves mitochondria—when mitochondrial function fails, the body breaks down."      Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio     Resources: Paleovalley Bone Broth Protein: Save 15% on grass-fed bone broth protein at paleovalley.com/jockers.   Connect with Jason Prall: Book:  https://amzn.to/3YC78Wt Website:  humanlongevityfilm.com, beyondlongevitybook.com   Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/ 

What if the anxiety, burnout, inflammation, or exhaustion you carry didn't begin with you?In this solo episode, Dr. Taz explores the emerging science behind generational trauma and how stress, fear, and survival patterns can be passed down biologically through mitochondrial DNA, the nervous system, and hormonal pathways. She explains why some people struggle with symptoms that don't resolve despite doing everything right, and how ancestral trauma may be quietly shaping inflammation, cortisol levels, emotional regulation, and energy production across generations.You will learn how trauma can alter mitochondrial function, disrupt the HPA axis, and create inherited patterns of hypervigilance, anxiety, burnout, and chronic disease. Dr. Taz introduces her five body map framework, physical, mental, emotional, spiritual, and community, to help you understand where inherited trauma may be showing up and how healing becomes possible when all layers are addressed.Dr. Taz shares: • How trauma can be transmitted biologically through mitochondrial DNA passed down the maternal line • Why chronic inflammation, insulin resistance, and cortisol dysregulation often appear in families with histories of displacement, silence, or survival stress • The signs of inherited nervous system patterns, including hypervigilance, fear based thinking, emotional suppression, and burnout that starts early • How ancestral trauma affects hormones, energy production, mental health, and emotional regulation • Why family secrets, shame, and silence can destabilize the entire family ecosystem and show up as disease • The five body map approach to screening generational trauma across physical, mental, emotional, spiritual, and community layers • Practical ways to begin healing, including nervous system regulation, storytelling, somatic release, mitochondrial support, and restoring safe connection within familiesWhether you are dealing with unexplained symptoms, chronic stress, emotional patterns that seem bigger than your life experience, or simply want to understand your family's health history more deeply, this episode offers a new lens on healing. You may inherit biology, but you can change how it is expressed and what gets passed forward.Stay Connected:Connect further to Hol+ at https://holplus.co/- Don't forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Follow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsGet your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseHost & Production TeamHost: Dr. Taz; Produced by ClipGrowth.com (Producer: Pat Gostek) (00:00) - Hi everyone, it's Dr. Taz. Before we get into today's episode, I just wanna pause and say thank you. Your messages, your shares, your stories are, the reason we make Whole Plus every conversation here is about connecting the science, the intuition, and everyday life together so you can feel more like yourself. (00:00) - if you haven't already hit that subscribe or follow button, it helps us reach more people who need this. All right, let's begin. What if the pain you [00:00:30] carry didn't start with you? Science now shows that trauma can be passed through generations, not just through stories or behaviors, but through biological changes in the body itself. (00:00) - this episode, we're exploring the connection between ancestral trauma and mitochondrial DNA and how your body might still be echoing the stress, the fear, or the survival patterns of your lineage. The gift of being in practice for over 16 years and seeing, I don't know how [00:01:00] many patients, I think collectively as, uh, a series of whole plus clinics were at 60, 70,000. (00:00) - the gift of seeing a patient day in and day out and following them through their journey. Allows us as providers a lot of time to think, observe, learn, and listen. And one of the things that has always confused me until recently is why some people have symptoms or have issues without any explanation.[00:01:30] (00:00) - done all the right things. They're following the diet, they're exercising, they are doing all the things they're supposed to do. They've got those wellness routines down, red, light, blue, light, you name it, they're doing it, but they're still not well. And while I could have a conversation with all of you about chemistry and biology and physiology, here's what maturity and time has taught me. (00:00) - healing and being well doesn't exist on [00:02:00] one plane. It's not just about the numbers and the data. It's actually a whole lot more, so much more that it may even be linked to your generational trauma. Now, bear with me for a second. Please don't roll your eyes and change the channel or flip the screen. (00:00) - is important information and we are just beginning to understand what all of this means and how it's all connected. I've had many opportunities to observe [00:02:30] this. Some of them begin right in our home. I have watched as the women in our family have a very similar look in their eye demeanor way of talking tone. (00:00) - name it. Some of it we could explain away. My mom was an immigrant, came here at a very young age, 17, 18, 19 years old, had an arranged marriage. She had, I thought, the insecurity of being an immigrant, of being somebody in a new [00:03:00] country without a community. And I always explained away her inability or fear. (00:00) - of in terms of taking action or taking next steps as a part of that story, the immigrant story, right? I, I can't imagine what so many immigrants go through to get here and then to build a life in a family of their own, leaving behind mothers and fathers, brothers and sisters, huge families. So I explained her story away that way. (00:00) - then there [00:03:30] was me and I grew up, as I've shared sometimes in a slightly chaotic, dysfunctional childhood home, and I don't wanna get into all of those details, but I had that same glimmer of fear and insecurity that I saw in my mom. But let's fast forward to my daughter all these years later, growing up in a pampered home with a father that dotes on her. (00:00) - we doted on her even a bit too much, but regardless, had all the comforts and the [00:04:00] security that anybody externally could provide. But guess what? The same glimmer, that same sparkle, that same sort of tone. Something, I can't describe it, where there's fear...

Popular media leverage weak study to criticize RFK Jr.'s rethink of standard recommendations for saturated fat avoidance; Poor quality plant-based diets hike cardio risk; A listener complains his lp(a) is going up with age despite his healthy diet, lifestyle; Scientists pinpoint cocoa ingredient that slows aging; Berry proanthocyanidins preserve brain power; Tattooing may promote inflammation, undermine immunity.

Country singer Jellyroll dishes on his triple-digit weight loss odyssey; DGL for GERD—will it raise blood pressure? CBD curbs aggression in dogs; Hundreds of environmental chemicals may imbalance our microbiomes; ADHD isn't just a malady—it may impart unrecognized superpowers; The evolutionary mismatch between our ancient genes and modern artificial environments; Could napping improve cognitive function? Heart attacks, lung problems soared after LA wildfires; HHS Secretary RFK Jr. focuses attention on inadequate testing, treatments for chronic Lyme Disease.

Dr. Martin Picard, PhD, is a professor of behavioral medicine at Columbia University and an expert on how our behaviors and psychology shape cellular energy production and rates of aging. He explains that your mitochondria don't just “make energy”; they translate what you do—your mindset and your relationships—into the energy you experience as vitality or lack thereof. He explains how exercise, nutrition, sleep, meditation, and even certain thought patterns and our sense of purpose can charge our cells like batteries. He also shares findings that hair greying is the result of cellular stress and is reversible. This episode links physical and mental ‘energy' with cellular energy and provides science-supported tools to improve your physical and mental health. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Helix: https://helixsleep.com/huberman Lingo: https://hellolingo.com/huberman Function: https://functionhealth.com/huberman Waking Up: https://wakingup.com/huberman Timestamps (00:00:00) Martin Picard (00:03:50) What is Energy?, Energy Flow & Transformation (00:07:53) Energy, Vitality, Emotions, Sensory Perception (00:14:18) Sponsors: Helix Sleep & Lingo (00:17:19) “Mito-Centric” View of World, Mitochondrial Energy & Information Patterns (00:25:26) Organelles, Mitochondria & Energy Transformation; Maternal Genes (00:31:12) Mitotypes & Differentiation, Mitochondria as “Social Organisms” (00:36:52) Food & Dysfunctional Energy Transformation (00:40:02) Lifestyle Choices & Interests, Physiological Growth (00:46:39) Pregnancy, Amenorrhea; Illness & Tiredness (00:51:07) Sponsor: AG1 (00:52:29) Energy Transformation & Distribution; Body's Wisdom, Feeling Sick (00:56:27) Tool: Feel Your Energy; Breath & Energy (01:02:31) Flow of Energy; Trade-Offs, Life Purpose & Enjoyment (01:10:15) Biology, Meaningful Experiences & Energy Flow (01:16:27) Sponsor: Function (00:18:15) Inflammation, Energetic Flow (01:20:43) Child Prodigies, Species Lifespan & Mitochondrial Metabolism; Aging (01:28:56) Lifestyle & Aging: Exercise, Fasting; Inflammation, Sleep, Stimulants (01:37:06) Energetic Stress Signals, GDF-15, Cancer, Heart Failure (01:42:18) Genes, Lifestyle & Aging (01:47:54) Gray Hair Reversal, Stress; Inflammation & Aging (01:57:37) Energy Recovery, Sleep & Mitochondrial Function, Stress, Meditation (02:05:16) Tools: Yoga Nidra, NSDR; Pre-Sleep Relaxation, Energy & Restorative Sleep (02:10:58) Diet & Individualization, Clinical Trials; Mitochondria & Nutrition, Keto (02:20:14) Alcohol & Energy Budget; Stress (02:25:02) Exercise, Increase Mitochondria, Overtraining; Resistance & Growth (02:33:06) Sponsor: Waking Up (02:34:41) Supplements & Mitochondria Health, Deficiencies, SS31, Methylene Blue (02:41:31) Energy Flow & Experiences, Balance (02:49:13) Transform Through Resistance, Energetic Awareness, Connection (02:56:05) Food Overconsumption & Mitochondria Disruption; Tissues & Mitochondria (03:01:02) Mitochondrial Health Test; Tool: Ways to Increase Energy; Meditation (03:06:10) Peptides; Fertility Supplements, Urolithin A; Electromagnetic Fields (03:12:16) Acknowledgements (03:14:15) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Glen Jeffery, PhD, is a professor of neuroscience at University College London and a leading expert on how different colors (wavelengths) of light impact cellular, organ and overall health. He explains that long-wavelength light (red, near-infrared and infrared) can enter the body and brain to enhance mitochondrial function and thereby improve metabolism, eyesight, blood glucose regulation, mood, hormones and more. We also discuss how short-wavelength light from LED bulbs can impair mitochondrial health and why balanced, full-spectrum light is essential for health. Dr. Jeffery shares simple yet powerful ways to use natural and artificial light sources to enhance your metabolic function, eyesight and longevity. Sponsors AG1: https://drinkag1.com/huberman Wealthfront*: https://wealthfront.com/huberman Joovv: https://joovv.com/huberman Rorra: https://rorra.com/huberman Function: https://functionhealth.com/huberman Timestamps 00:00 Glen Jeffery 03:12 Light, Ultraviolet (UV), Visible & Infrared (IR) Light 06:25 Light's Impact on the Body & Light, Sunburn, Cataracts 09:55 UV Light, All-Cause Mortality, Skin Cancer 14:55 Sponsors: Wealthfront & Joovv 17:58 Light Impacts Mitochondria Function & Structure, Long-Wavelength Light (Red/IR), Nano Water 25:00 Long-Wavelength Light Passes Through Clothing & Body; Tissue Scattering 30:08 Long-Wavelength Light & Blood Glucose; Mitochondria 36:19 Red Light, Parkinson's Disease, Cell Death; Eye Rods & Aging; Mitochondria Community 42:46 Red/IR Light, Skull & Brain; Safe Non-Ionizing Radiation 48:22 Sponsors: AG1 & Rorra 51:04 Offsetting Retinal Aging, Improve Vision & Long-Wavelength Light 59:28 Tool: Long-Wavelength Light & Preserve Retinal Mitochondria; Sunlight 1:03:50 Mitochondrial Theory of Aging, Circadian Rhythm & Mitochondria 1:07:57 Tool: Improve Vision with Long-Wavelength Light 1:10:44 Macular Degeneration, Rescuing Vision, Early Intervention 1:13:59 Light Effects at Local vs Distant Tissues, Immune System, Body Communication 1:19:09 Sponsor: Function 1:20:56 Short-Wavelength Light, LED Light, Mitochondria & Serious Health Detriments 1:28:39 Lifespan, LED Lights; Sunlight & Balanced Wavelengths; "Sunlike" Marketing 1:34:45 Fires, Incandescent Lights vs LED Lights, Lasers; Long-Wavelength Devices 1:39:07 Incandescent & Halogen Bulbs, Mitochondria & Built Environments 1:45:19 Windows, Light & Office Work; Screens, Kids & Myopia; Tools: Plants; Lighting 1:55:56 Bring the Outdoors Indoors 2:00:35 Tool: Candlelight; Dim Halogen Lamps 2:05:06 Mitochondrial Diseases, Children & Long-Wavelength Light; Light Bulbs 2:11:53 Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter *This experience may not be representative of other Wealthfront clients, and there is no guarantee of future performance or success. Experiences will vary. The Cash Account, which is not a deposit account, is offered by Wealthfront Brokerage LLC, member FINRA/SIPC.  Wealthfront Brokerage is not a bank. The base APY is 3.50% on cash deposits as of November 07, 2025, is representative, subject to change, and requires no minimum. If eligible for the overall boosted rate of 4.15% offered in connection with this promo, your boosted rate is also subject to change if the base rate decreases during the 3 month promo period. Funds in the Cash Account are swept to program banks, where it earns the variable APY. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer. Investment advisory services are provided by Wealthfront Advisers LLC, an SEC-registered investment adviser. Securities investments: not bank deposits, bank-guaranteed or FDIC-insured, and may lose value. Learn more about your ad choices. Visit megaphone.fm/adchoices