Podcasts about mitochondria

Daylight Savings Time changeover health myths busted; A doctor breaks her ankle and is billed $64,000 in uncovered expenses; Vitamin D shields life-prolonging telomeres, may help depression; The vaunted DASH Diet for hypertension faces off against low-carb alternative; The critical first 1000 days after conception—early life sugar avoidance yields major later life health dividends; Do you really need hot water to disinfect your hands?

Send us a textHow mitochondria travel between cells and how this hidden communication shapes metabolism, immunity, and even potential therapies.Episode Summary: Dr. Jon Brestoff talks about mitochondrial dynamics inside cells, their transfer between unrelated cells (distinct from inheritance during division), and its roles in adipose tissue communication, macrophage cleanup, and systemic metabolic signaling; they explore how high-fat diets disrupt this process, potential hormetic benefits, therapeutic mitochondria transplantation for diseases like Leigh syndrome and obesity, and broader immunometabolism crosstalk.About the guest: Jon Brestoff, MD, PhD is an associate professor of pathology and immunology at Washington University School of Medicine in St. Louis, where he directs the Initiative for Immunometabolism.Discussion Points:Mitochondria per cell range from ~100-5000; they move via fusion/fission, vertical inheritance (cell division), or horizontal transfer without division.Transfer mechanisms: free release, extracellular vesicles, or tunneling nanotubes using cytoskeleton transport.In healthy fat tissue, adipocytes routinely donate mitochondria to macrophages for degradation (quality control); high-fat (lard-based, long-chain FA) diets block macrophage uptake, diverting mitochondria to other organs.Diverted mitochondria may induce “mito-hormesis” (mild oxidative stress boosting antioxidants) or signal adipocyte metabolic status inter-organ.Mitochondria transplantation shows promise in animal models for ischemia-reperfusion, obesity, and mitochondrial diseases.Immune cells prefer glycolysis but have low mitochondrial biomass; transplanted mitochondria tilt T-cells toward anti-inflammatory regulatory phenotype.Circulating cell-free mitochondria rival immune cell numbers.Obesity inflammation stems from dying oversized adipocytes releasing lipids/mitochondria, forming crown-like structures with pro-inflammatory macrophages.Leigh syndrome from genetic mutations disrupting the electron transport chain.Transfer may be an evolutionary relic of endosymbiosis; cells may selectively use exogenous mitochondria like a “generator” during metabolic crisis.Reference Paper:Study: The power and potential of mitochondria transferRelated Episode:M&M 260: Energy Resistance Principle in Life, Healing & Disease | Martin Picard & Nirosha MuruganSupport the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

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In this episode of the Smarter Not Harder Podcast, Dr. Latt Mansor joins Jodi Duval for a deep-dive into ketones, mitochondria, and metabolic flexibility — the science of how your body creates, manages, and optimizes energy. From brain performance to heart health, this conversation bridges Oxford-level physiology, real-world biohacking, and the future of metabolic medicine. Join us as we explore: How ketones work as both fuel and signaling molecules to power your brain, muscles, and heart Why metabolic flexibility is the key to longevity, resilience, and cognitive clarity The difference between endogenous and exogenous ketones — and how to use Ketone IQ effectively The link between mitochondrial health, NAD⁺, and energy metabolism Groundbreaking research on ketones in Alzheimer's, mental health, and heart-failure recovery This episode is for you if: You want to understand how ketones can boost cognition, focus, and energy You're a clinician, athlete, or optimizer seeking to personalize supplementation and performance You're curious about the future of metabolic psychiatry and mitochondrial medicine You want smarter, not harder, ways to enhance metabolism, longevity, and recovery You can also find this episode on...YouTube: https://youtu.be/ictAuB43lIs Find more from Dr. Latt Mansor:Website: https://ketone.com Instagram: https://instagram.com/lattmansor/ LinkedIn: https://linkedin.com/in/lattmansor Find more from Smarter Not Harder:Website: Smarter Not Harder Podcast Instagram: https://instagram.com/troscriptions Get 10% Off your Clinical Metabolomics Module at HOMeHOPe using code POD10 → https://homehope.org/products/clinical-metabolomics Get 10% Off your Troscriptions order with code PODCAST10 → https://troscriptions.com Get daily metabolic-health content and future-of-medicine insights by following @troscriptions on Instagram.

Dr. Hoffman continues his conversation with  Dr. Nathan Bryan, a pioneering scientist, health innovator, biotech entrepreneur, and author of "The Secret of Nitric Oxide: Bringing the Science to Life." 

In this episode of the Intelligent Medicine podcast, Dr. Ronald Hoffman discusses the vital role of nitric oxide in human health with expert Dr. Nathan Bryan, a pioneering scientist, health innovator, and biotech entrepreneur who's reshaping the conversation around longevity, human performance, and the truth behind modern health. He's author of "The Secret of Nitric Oxide: Bringing the Science to Life." They explore the science behind nitric oxide, its numerous benefits, including its impact on cardiovascular health and erectile function, and the misconceptions surrounding common supplementation methods. Dr. Bryan explains how his research led to the development of effective nitric oxide supplements and a nitric oxide-friendly lifestyle. They also address the safety and efficacy of combining nitric oxide support with erectile dysfunction medications, and Dr. Bryan shares insights into ongoing research and future innovations in the field.

This week I interviewed Katie Hardie! Katie is a Board-Certified Holistic Nutritionist and FDN Practitioner who helps high performers reclaim their energy, optimize nutrition, and achieve lasting results through bio individual, science-driven programs. We discussed how most of your health gains will be done in the kitchen along with:- what to buy when going to the grocery store- the importance of functional medicine- Katie's favorite tests for optimal healthand her one tip to get your body back to what it once was!Connect with Katie:Website: https://www.mypeak365.com/ Instagram: https://www.instagram.com/mypeak365/ Links:Interested in Upgrading your Mitochondria, Improving Energy and Sleep! Check out Troscriptions: https://bit.ly/4ik5kK5Use Discount Code for 10% OFF: EATCLEAN----Watch Get Lean Eat Clean podcast video episodes on YouTube!YouTube.com/@briangryn3680-----How to Take Simple Steps to Reclaim the Body, Energy, and Strength You Had 10-15 Years Ago Using My Stepladder System:https://www.stepladdersystem.com/----B.rad Whey Protein Isolate Superfuel:The Best Protein on The Planet! Available in Two Delicious Flavors: Vanilla Bean and Cocoa BeanUse Coupon Code glec10off for 10% off your order!Amazon (case sensitive): GLEC10OFFB.rad Nutrition.com: glec10offhttps://a.co/d/731gssV----My favorite health bars with clean ingredients!https://www.eatprima.com/BRIAN6816310% OFF with this link!----| Listen to the Get Lean Eat Clean Podcast |►Apple Podcasts | https://podcasts.apple.com/us/podcast/get-lean-eat-clean/id1540391210►Spotify | https://open.spotify.com/show/0QmJzYZsdV6tUNbDxaPJjS| Connect with Brian |►Website | https://www.briangryn.com►Instagram | https://www.instagram.com/bdgryn►Facebook | https://www.facebook.com/getleanandeatclean►Twitter | https://twitter.com/grynnerwinner

Welcome to the Mind Muscle Connection Podcast!In this episode, I sit down with Dr. Phil Batterson to talk about VO2 Max for Lifters: The Untapped Lever for Performance, Fat Loss & Longevity.We cover why it matters for performance, how it connects to recovery and fat loss, and simple ways to improve it without wrecking your lifting progress. If you're serious about building muscle or your fitness journey, this episode is a must listen!Let's talk about:00:47 Introduction to Dr. Phil Batterson04:22 Mitochondria & why it matters06:00 Endurance and Cardio10:51 Cardio vs Muscle Gains30:21 Dr. Phil's training38:40 VO2 Max01:06:23 How VO2 max impacts lifters01:09:10 Misconceptions01:11:16 Where to find Dr. PhilFollow Dr. Phil Batterson on Instagram:https://www.instagram.com/drphilbatterson/Follow me on Instagram for more information and education:  jeffhoehn_FREE 30 Min Strategy Call: HEREBody Recomp Masterclass: HERENutrition Periodization Masterclass: HEREHow You Can Work With Me?: HERECoaching application: HEREBody Recomp Checklist 2.0: https://chipper-producer-6244.kit.com/26b5c9f94a

In this episode of Ageless Future, Regan Archibald explores the groundbreaking molecule SLU-PP-332, a compound designed to mimic the metabolic benefits of exercise by activating key genetic and mitochondrial pathways. Originally developed by researchers at St. Louis University, SLU-PP-332 works through the ERR-alpha and AMPK pathways, promoting fat oxidation, mitochondrial biogenesis, and improved insulin sensitivity—without the oxidative stress of overtraining. Regan discusses how animal studies demonstrated dramatic improvements in endurance, fat loss, and glucose control, and shares his own experience using SLU-PP-332 to enhance VO₂ max, energy, and recovery. He also outlines its potential applications for metabolic syndrome, muscle loss, inflammation, and even post-COVID mitochondrial dysfunction. The episode concludes with practical insights on stacking SLU-PP-332 with other peptides like MOTS-c, 5-Amino-1MQ, and BPC-157 for comprehensive metabolic rejuvenation, while emphasizing the foundation of longevity medicine: optimizing insulin sensitivity, mitochondrial efficiency, and consistent physical conditioning.www.agelessfuture.com

Discover how decoding your DNA can unlock the full potential of plant medicine. This episode delivers a cannabis masterclass for biohackers, revealing how personalized genetics are transforming human performance, brain optimization, and longevity. You'll learn how to identify your ideal cannabis and supplement protocols, balance your endocannabinoid system, and turn precision data into powerful healing. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Len May, MSc, visionary authority in personalized medicine and CEO of EndoDNA, the world leader in DNA-based wellness technology. With over 25 years of pioneering work in genomics, epigenetics, and medicinal cannabis, Len's patented DNA decoding system maps your unique genotypes to design tailor-made health solutions. His company holds the world's largest real-world efficacy database in precision wellness, integrating functional medicine, AI-driven analytics, and genetic data to create personalized blueprints for optimal brain function and performance. Together, Dave and Len explore how your genetic code determines how you respond to cannabis, psychedelics, nootropics, and supplements—and how to use that data to reduce anxiety, improve sleep optimization, and enhance focus. You'll learn how decoding your DNA can guide anti-aging strategies, mitochondrial performance, metabolism, and neuroplasticity, revealing new ways to live longer and smarter. This episode dives deep into the intersection of cannabis science, genomics, and biohacking. You'll discover how genetic polymorphisms influence mood, cognition, and stress response, and how personalized medicine can help you make smarter decisions around ketosis, fasting, and recovery. From optimizing the endocannabinoid system to hacking your biology for resilience and longevity, this is the future of functional medicine in action. You'll Learn: • How the endocannabinoid system regulates mood, focus, pain, and stress response • Which genetic polymorphisms affect cannabis sensitivity, anxiety risk, and dosing windows • How to use DNA testing to select cannabinoid and terpene ratios that fit your biology • Why delivery method matters and when sublingual dosing outperforms inhalation • How personalized cannabis protocols can support sleep optimization, recovery, and emotional regulation • The role of cannabinoids in mitochondrial function, neuroplasticity, and cognitive performance • How pharmacogenomics reduces antidepressant side effects and improves treatment matching • How to screen genetics for safer psychedelic use and avoid adverse reactions • What HLA and related markers reveal about mold sensitivity and inflammation This is essential listening for anyone serious about biohacking, brain optimization, longevity, anti-aging, functional medicine, and living Smarter Not Harder—with precision tools designed to upgrade your mind and body at the genetic level. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: cannabis biohacking, cannabis masterclass, Dave Asprey cannabis, DNA decoding, genetic testing for cannabis, personalized medicine, endocannabinoid system, cannabis genomics, cannabis and DNA, cannabis and genetics, cannabis nootropics, plant medicine biohacking, cannabis brain optimization, cannabis and neuroplasticity, cannabis for focus, cannabis and mitochondria, cannabis metabolism, cannabis for sleep, cannabis anti-aging, precision wellness, functional medicine, cannabis longevity, EndoDNA, Len May, cannabis and AI, biohacking genetics, cannabis and fasting, cannabis and ketosis, personalized supplements, cannabis and mood, cannabis stress response, genetic biohacking, cannabis cognitive performance Thank you to our sponsors! -Screenfit | Get your at-home eye training program for 40% off using code DAVE at https://www.screenfit.com/dave. -Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. -iRestore | Use code DAVE at https://www.irestore.com/ to unlock an exclusive discount on the iRestore Elite. Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 – Trailer • 1:25 – Introduction • 7:02 – Cannabis & The Endocannabinoid System • 13:30 – How It Works • 21:38 – Brain Health & Clinical Studies • 26:52 – Psychedelics & Genetic Testing • 31:37 – Genetics vs Epigenetics • 34:53 – Antidepressant Safety • 40:41 – Cannabis Success Stories • 46:02 – ADHD & Personality Genes • 50:54 – Mold, Nicotine & Mitochondria • 55:27 – GLP-1 & Metabolism • 1:00:34 – Microbiome & Medical Freedom See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Hydrogen is one of the most abundant elements in the universe, and according to today's guest, it's also one of the most misunderstood and underutilized when it comes to human health. I'm sitting down once again with Greg the Hydrogen Man, a molecular hydrogen expert, researcher, and host of the Uprising144K YouTube channel, to go deep into the truth behind hydrogen therapy.Greg shares the extraordinary story of how hydrogen helped him rise from a wheelchair-bound state and serious heart condition to full health, and why he believes purity and production methods make all the difference. He pulls back the curtain on industry misinformation, the corruption behind cheap machines, and why Japan is decades ahead of the US when it comes to hydrogen research and medical applications. Visit lukestorey.com/holyhydrogen and use code LUKE for $100 off the Lourdes Hydrofix.DISCLAIMER: This podcast is for educational purposes only and not intended for diagnosing or treating illnesses. The hosts disclaim responsibility for any adverse effects from using the information presented. Consult your healthcare provider before using referenced products. This podcast may include paid endorsements.THIS SHOW IS BROUGHT TO YOU BY:LITTLE SAINTS | Visit lukestorey.com/littlesaints and use code LUKE to get 20% off your first order. EONS | Visit lukestorey.com/eons and use code LUKE20 to save 20%.PIQUE | For a limited time, get 20% off for life + a free starter kit at piquelife.com/lukeFLFE | Try Focused Life-Force Energy for FREE for 15 days at lukestorey.com/flfeMORE ABOUT THIS EPISODE:(00:00:00) Uprising144K & Greg's Return(00:34:12) Clean Water First: Carbon Distillation, Minerals, & the Microbiome(00:45:34) Hydrogen as the Body's Shield Against Modern Stressors(00:53:31) Hydrogen, Mitochondria, & the Balance of Life(01:05:04) The Easiest Health Habit You're Not DoingResources:• Website: holyhydrogen.com • Instagram: instagram.com/uprising144k_ • Facebook: facebook.com/holyhydrogen • X: x.com/hydrogenman2 • X: x.com/holyhydrogen1 • TikTok: tiktok.com/@holy.hydrogen • YouTube: youtube.com/@UPRISING144K • YouTube: youtube.com/@HappyJapan-jh6zz • Rumble:

Send us a textA biophysical rethink of life, health, and disease through the lens of the Energy Resistance Principle (ERP).Episode Summary: A reframe of biology as energy flow through resistance rather than mere molecular machinery, introducing the Energy Resistance Principle (ERP): life requires a Goldilocks balance of electron flow from food to oxygen via mitochondria; too much or too little resistance drives aging, disease, and death. Explain mitochondria as energy transformers, link ERP to insulin resistance, psychiatric disorders, and healing, and explore health as a dynamic field-like state optimized by flux modulation.About the guest: Nirosha Murugan, PhD is a biophysicist studying how physical signals pattern biology to decode and reprogram health; Martin Picard, PhD is a mitochondrial psychobiologist at Columbia University, exploring how mitochondrial energy dynamics connect to human experiences, health, and healing. They collaborate on biophotons, light emission, and multi-scale energy signaling.Discussion Points:Mitochondria transform electrons from food into versatile electricity via proton gradients.Energy Resistance Principle: transformation needs resistance; chronic high resistance causes dissipative heat, damage, aging.GDF15 cytokine signals mitochondrial stress to brain, triggering energy conservation/mobilization.Insulin resistance: adaptive defense against electron overload, reversible by fasting/exercise.Psychiatric illness: excess brain energy resistance; exercise, keto, psychedelics redistribute flux.Health: dynamic optimization of energy resistance, not absence of disease.Healing: daily recovery from micro-damage via balanced resistance.Future: energy-based diagnostics/therapies (light, TMS) over molecule-only drugs.*Not medical advice.Reference Paper: The energy resistance principleRelated Episode:M&M 70: Mitochondria, Aging, Cellular Energy, Metabolism, Gray Hair Reversal & Brain-Body Communication | Martin PicardSupport the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

In this episode, Penny welcomes functional medicine expert Sharon Yeh — former clinical pharmacist turned mitochondrial and circadian wellness practitioner — to explore how simple but profound changes in light exposure, timing of meals, and environmental rhythms can unlock healing on every level: body, mind and soul.

Autism is exponentially on the rise and the question is, "Why?" Dr. Richard Boles, MD explains how there's hope for a better life by recharging the brain's battery packs by fueling the mitochondria and this process may be creating a significant impact for improving autism.https://www.neuroneeds.comDrboles@molecularmito.com______________________https://www.thequestforwonder.com/amazings-seriesYou can take advantage of one of the best holistic health conferences anywhere and enter Discount Promo Code – GRIT for 30% off all My EHI Aloha courses and Healing for the A.G.E.S. events and replays by visitinghttps://myehialoha.org/#GRIT--------------------------Check out all of our vendors at: https://patriotswithgrit.com/patriot-partners/ SPONSORS FOR THIS VIDEO❤️ Cardio Miracle – One Drink. Endless Benefits.Feel steady energy, sharper clarity, and stronger resilience every day.Own your freedom in health & experience the full power your body was designed for.

Creatine's story has been far too small for its biology. Most people still see it as a supplement for strength or cognitive performance, but its most important work happens inside the mitochondria.In this episode, we explore a side of creatine few people talk about: how it may function as mitochondrial medicine. We'll break down 3 distinct ways creatine acts in and supports the mitochondria; roles that could reshape how we think about energy, resilience, and cellular health.  And beyond that, how creatine may be one of the few molecules that can both diagnose and treat mitochondrial dysfunction. 00:00 Understanding Mitochondrial Dysfunction00:43 Introduction to Creatine's Role01:16 Mitochondrial Dysfunction Explained01:56 Creatine as a Theranostic Agent02:57 Mechanisms of Creatine in Mitochondria04:09 Therapeutic Roles of Creatine05:22 Redox Control and Antioxidant Properties06:27 Conclusion: The Unique Power of Creatine PMID: 40948982

Here I explain the lymphatic system, a crucial bodily network for overall health and appearance. I explain how the lymphatic system works to remove cellular waste and fluid from your organs and combat infections. I provide science-based tools that support your lymphatic system for the sake of health and appearance, including: how to reduce fluid retention in your limbs, trunk or face, how to eliminate 'bags' under your eyes and brain fog, and how to improve cardiac health and longevity. Because your lymphatic system lacks a central pump, it needs the mechanical forces generated by specific types of bodily movement, breathing and pressure to circulate your lymph properly, and I explain how you can activate these. I also explain how to support optimal functioning of your glymphatic system, a brain- and spinal cord waste-clearing system active during sleep that is crucial for brain functioning and longevity, including to prevent dementia. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AGZ by AG1: https://drinkagz.com/huberman LMNT: https://drinklmnt.com/huberman David: https://davidprotein.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman Timestamps (00:00:00) Lymphatic System (00:04:11) Circulatory System, Heart; Oxygen, Nutrient & Waste Transfer (00:11:03) Lymphatic System, Fluid, Lymphedema, Chronic Inflammation; Brain Fog (00:14:52) Sponsor: LMNT & David Protein (00:17:28) Lymphatic Vessels, Tool: Enhance Lymphatic Drainage with Movement (00:26:24) Tools: Jumping (Rebounding), Treading Water, Swimming (00:27:41) Tool: Swelling, Lymphatic Drainage & Diaphragmatic Breathing (00:32:05) Swimming & Lymphatic Flow; Tai Chi (00:34:00) Lymphatic Massage, Cancer & Lymphedema; Jade Roller & Gua Sha (00:37:28) Sponsor: AGZ by AG1 (00:38:56) Lymph Flow, Tool: Lymphatic Massage & Manual Lymphatic Drainage (00:45:02) Immune Function of Lymphatic System, Sore Lymph Nodes (00:54:24) Cancer Treatment, Lymph Nodes & Lymphedema (00:57:02) Limb Swelling, Minor Lymphedema & Inflammation, Lymphatic Boots (01:00:09) Sponsors: Eight Sleep (01:01:43) Glymphatic System, Brain & Sleep (01:05:56) Sleep & Brain Waste Recycling; Discovery of the Glymphatic System (01:12:24) Enhance Glymphatic Clearance, Brain Fog, Age, Tool: Side Sleeping Position (01:15:54) Tools: Optimize Sleep, Cardiovascular Exercise, Elevate Feet, Pillow (01:17:29) Puffy Face, Tool: Lymphatic & Facial Massage (01:21:23) Sponsor: Function (01:23:11) Tool: Hydration & Lymphatic Support (01:24:48) Tool: Cardiovascular Exercise & Lymphatic Vessels, Heart, Aging (01:31:06) Tool: Infrared & Red Light, Mitochondria, Lymphedema, Skin Appearance (01:36:08) Key Takeaways (01:37:21) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

Episode Highlights With SarahLight and leptin and how these interplay with each otherThe importance of leptin and what it isAll of our hormones are circadian How to support these hormones naturallyLeptin wasn't even discovered and studied until 1994 and why we still don't hear much about it even thought it is so importantHow this interplays with thyroid health and why this is important What it means when leptin is low or highThe mitochondrial aspect of these hormones and how light environment impacts thisHow much our light environment affects almost every aspect of healthMost important factors we can shift in our light environmentWhat to know about UV light and how much of each type of light we needWhat red and infrared light at sunrise and sunset do for hormones and mitochondriaWhy hunger in the morning is a good thing and important to haveRed light therapy panels don't have far infrared light and it is available in the sun daily! If our mitochondria think we are in danger, even if we have the perfect diet, they can down-regulate to keep us safe and how to signal safetyHer own amazing fertility journey and how these factors helped even when IVF failedThyroid specific advice for supporting the thyroid and tapering off medsHow a leptin reset can help and how to do itStrategies for timing food and carbs with the sun to get nourishment without gaining weightHer best tips for leptin reset and getting all these things into rangePerimenopause and how light and leptin come into playResources MentionedAll of Sarah's courses - Use code Katie for 15% offMyCircadianAppSarah's website, her Instagram, and YouTubeEvolving Wellness PodcastSarah's Free EbooksFunction Health lab testing

NEW! Support your strength and muscle goals with PUORI Creatine+ — a clean, effective creatine monohydrate supplement enhanced with taurine. Get 20% off at puori.com/VANESSA In this masterclass episode, Vanessa sits down with Dr. David Church, one of the most exciting young researchers in protein metabolism and a mentee of Dr. Arny Ferrando and Dr. Robert Wolfe. Together, they break down the latest science on protein timing, distribution, and supplementation — and how to apply it to achieve fat loss, preserve muscle, and enhance cognition. You'll learn: • How stable isotope tracer studies work and what they reveal about muscle protein synthesis (MPS). • The minimum protein per meal needed to trigger muscle growth and repair — and whether you can hit it with two meals a day. • The truth about intermittent fasting and muscle preservation — what happens to MPS in 2-meal and 1-meal-a-day patterns. • Why older adults and women over 40 face anabolic resistance and how EAAs (essential amino acids) can help overcome it. • What happens when you double your protein intake from 0.8 g/kg to 1.6 g/kg — and why distribution may matter less than total intake. • The surprising power of small doses of EAAs in muscle maintenance and cognitive support. • Why creatine is foundational for women, including new research showing benefits for brain health and sleep deprivation. • How to optimize body recomposition — burning fat while protecting lean mass — even during calorie restriction. • The difference between supplemental vs. replacement nutrition, and why EAAs work for older adults with low appetite. • The synergy of protein + resistance training + sleep + activity in driving sustainable fat loss. OneSkin is powered by the breakthrough peptide OS-01, the first ingredient proven to reduce skin's biological age. I use the OS-01 Face and Eye formulas daily—they've transformed my skin's smoothness, firmness, and glow. Visit oneskin.co/VANESSA and use code VANESSA for 15% off your first purchase Dr. Church also shares his own daily stack — including why he takes 20 g of creatine per day and combines it with EAAs for energy, cognition, and recovery — plus his favorite high-protein meals for busy days. If you've ever wondered how to burn fat efficiently while protecting every gram of muscle, this episode is packed with evidence-based takeaways you can implement right away. Mentioned in this Episode: • Puori Creatine + – clean, third-party-tested creatine monohydrate with taurine • Essential amino acids for older adults and women facing anabolic resistance • Stable isotope tracer studies — how we truly measure MPS • Protein targets: 1.6–2.4 g/kg depending on activity and energy restriction • Pre-sleep protein and its impact on overnight MPS and metabolic rate Get delicious high protein meal recipes! Connect with Vanessa on Instagram @ketogenicgirl Free High-Protein Keto Guide  Get 20% off on the Tone LUX Crystal Red Light Therapy Mask or the Tone Device breath ketone analyzer at https://ketogenicgirl.com with the code VANESSA Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.

While we're making progress in TREATING cancer, worldwide cancer INCIDENCE is soaring, especially among young people; New guidelines for colon cancer screening urge earlier start at age 45; Rates of peanut allergy are declining as more parents follow revised advice to introduce nuts earlier to kids; What's with all the buzz about methylene blue? Legalization and stronger pot are creating an epidemic of ER visits for uncontrolled vomiting, debilitating abdominal pain; New smart toilet gives you a report card on your poop; When Zoloft doesn't work for anxiety.

New study suggests taking thyroid medication WITH food may be just as good as taking it on an empty stomach; Natural support for Parkinson's Disease; Reviving the lost art of handwriting may be key to kid's learning; Dr. Jeffrey Bland does a deep dive on why not all fish oils are alike.

Feeling burned out, inflamed, or stuck in survival mode? In this episode, Dr. Tim Jackson sits down with Dr. Mark Sherwood—naturopathic doctor, longevity expert, and former law-enforcement officer turned wellness leader—to reveal how true healing starts at the mitochondrial level. Learn how molecular hydrogen, red-light therapy, vagus-nerve activation, and emotional calm can reverse cellular stress, boost energy, and extend your healthspan. Discover why modern medicine often misses the root cause of aging and how you can take back control of your biology today.

In this special follow-up episode, we revisit one of our most talked-about conversations of the year — with Morley M. Robbins, author of [Cu]re Your Fatigue. After episode 306, listeners sent in thoughtful questions about blood donation, iron overload, copper supplementation, mitochondrial health, and the role of GHK-Cu peptides.In this conversation, Morley returns to unpack these complex topics with clarity and depth. We'll explore how iron moves into tissues, the implications of long-term copper IUD use, how to approach copper and iron balance strategically as we age, and why our mitochondria might just hold the key to vitality in our later decades.Whether you're navigating your own health journey or simply curious about how minerals shape aging, this is a conversation you won't want to miss.Morley Robbins' Root Cause Protocol is now available from our affiliate partner, Jigsaw Health. Click the following link for 10% off*: https://www.jigsawhealth.com/?rfsn=8710089.1dddcf3&utm_source=refersion&utm_medium=affiliate&utm_campaign=8710089.1dddcf3Watch for GHK-Cu coming soon from Auro Wellness and use the link below for 10% off this and other fine products.Connect with Morley Robbins at: 847-922-8061 morleyrobbins@gmail.com @therootcauseprotocolBUY [Cu]re Your Fatigue (2nd ed.) on Amazon and support this podcast at https://amzn.to/3JczMd3Article cited by Morley:Xu, J, Jia, Z, Knutson, MD, and Leeuwenburgh, C. Impaired Iron Status in Aging Research Int. J. Mol. Sci. 2012, 13, 2368-2386; doi:10.3390/ijms13022368Please, support The Aging Well Podcast by hitting the ‘like' button, subscribing/following the podcast, sharing with a friend, and….BUY the products you need to… age well from our trusted affiliates and support the mission of The Aging Well Podcast*.The Aging Well Podcast merchandise | Show how you are aging well | Use the promo code AGING WELL for free shipping on orders over $75 | https://theagingwellpodcast-shop.fourthwall.com/promo/AGINGWELLRebalance Health | products created by hormone health experts to lower cortisol, improve sleep, and minimize the impact of stress on the body and mind | https://get.aspr.app/SH1AkZ or https://rebalancehealth.com with the promo code: AGING WELLAuro Wellness | Glutaryl—Antioxidant spray that delivers high doses of glutathione (“Master Antioxidant”) | 10% off Code: AGINGWELL at https://aurowellness.com/agingwellpodcastBerkeley Life | Optimize nitric oxide levels | Purchase your starter kit at a 15% discount | Use the promo code: AGINGWELL15 | https://berkeleylife.pxf.io/c/6475525/3226696/31118Oxford Healthspan | Primeadine®, a plant-derived spermidine supplement | 10% off code: AGINGWELL | https://oxford-healthspan.myshopify.com/AgingWellJigsaw Health | Trusted supplements. “It's fun to feel good.” | Click the following link for 10% off: https://www.jigsawhealth.com/?rfsn=8710089.1dddcf3&utm_source=refersion&utm_medium=affiliate&utm_campaign=8710089.1dddcf3Prolon | The Fasting Mimicking Diet (FMD) is a revolutionary five-day nutrition program scientifically formulated to mimic the effects of a prolonged water fast while still allowing nourishment - supporting the benefits of fasting without the challenges and risks that come from water-only fasts. | For the best available discount always use this link: https://prolonlife.com/theagingwellpodcastThrive25—Your personal longevity advisor | https://www.thrive25.com/early-access?via=william-jeffreyFusionary Formulas | Combining Ayurvedic wisdom with Western science for optimal health support. | 15% off Code: AGINGWELL | https://fusionaryformulas.com?sca_ref=9678325.IHg5xYhdOzzke8ZrDr Lewis Nutrition | Fight neurodegeneration and cognitive decline with Daily Brain Care by Dr Lewis Nutrition—a proven daily formula designed to protect and restore brain function. | 10% off code: AGINGWELL or use the link: https://drlewisnutrition.com/AGINGWELL*We receive commission on these purchases. Thank you.

In this mind-expanding episode, Darin sits down with Dani Fontaine — researcher, practitioner, and expert on the human body's forgotten communication system: the endocannabinoid system. They unravel how this network regulates everything from mood and sleep to pain and consciousness — and why it was deliberately scrubbed from mainstream medical education. Dani reveals how cannabinoids, light, sound, and nature all communicate with our body's receptor fields — shaping the way we feel, heal, and perceive the world. Together they explore the profound spiritual and scientific implications of this hidden system, and how it connects us back to balance, nature, and truth.     What You'll Learn 00:00:00 - Welcome to the SuperLife Podcast 00:00:32 - Sponsor: Energy Bits 00:01:52 - Introducing Guest Danny Fontaine: Cannabis Pioneer and Plant Medicine Healer 00:04:54 - Deep Dive: What is the Endocannabinoid System (ECS)? 00:06:30 - ECS: The Homeostasis and Retrograde Signaling System 00:09:20 - ECS as a Receptive System for Subtle Energies and Environment 00:10:23 - Endocannabinoid System Toning (X-Tone) 00:12:58 - When the ECS Gets Worn and Depleted 00:16:34 - ECS Receptors on Every Cell, Fascia, and Neural Makeup 00:19:14 - How the ECS Breaks Down: The Impact of False Light 00:22:11 - The ECS and Non-Photon Rich Food 00:23:40 - Modulating the ECS Through the Six Senses (Touch and Breath) 00:24:38 - Mitochondria and ECS Receptors (MTK, CB1) 00:25:14 - Endogenous ECS and the Need for Proper Nutrients 00:27:11 - Cannabis as our Phyto Twin: The Plant Factor 00:27:57 - THC and the Suppression of Anandamide (Bliss Molecule) 00:31:44 - Sponsor: Fatty 15 00:35:25 - The Vast Amount of ECS Research & Medical Suppression 00:38:27 - Cannabinoids, Pain, and Individual Assessment 00:40:29 - Modulating ECS with Nature: Terpenes like Pinene 00:42:51 - Olfactory System as the Most Sophisticated Input 00:47:03 - ECS as the "Microscope Moment" for Health 00:48:23 - Pinene, CB1, and TRP Receptors in Pain Management 00:50:39 - The ECS, Collagen, and Hyaluronic Acid Fluctuation 00:51:44 - Working with the ECS for Faster Results (Cancer and Genetic Mutations) 00:55:06 - Sponsor: SuperLife Patreon 00:56:39 - Measuring the ECS with Bio-Field Technology 00:57:29 - The Danger of THC Stacking and Immunosuppression 00:59:30 - Overwhelmed Cells and Fake Inputs 01:00:12 - Hemp as a Homeostasis Plant for the Planet (Soil Remediation/Carbon) 01:02:06 - ECS Strength in Animals vs. Humans 01:04:08 - Why Cannabis and Hemp Were Suppressed 01:07:07 - The Historical Use of Cannabis in Medicine 01:08:12 - Hemp's Nutritional Profile (Amino Acids and Omegas) 01:09:37 - Ayahuasca, Receptor Overexpression, and Looping 01:13:33 - Importance of ECS Knowledge and Application 01:14:58 - Exercise, Anandamide, and ECS Toning 01:15:22 - Cold Plunge and Shocking the ECS and Hormones 01:17:16 - Takeaways: Light, Movement, Sound, and Breath 01:21:41 - ECS: The Main Signaling and Communication System 01:23:28 - Final Thoughts: ECS as the Conduit to Self and Spirit     Thank You to Our Sponsors: Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout. EnergyBits: Get 20% off your entire order by going to https://energybits.com/ and using code DARIN at checkout.     Find More from Dani Fontaine Instagram: @danifontaine Website: danifontaine.com Products: Try Dani's Nature Root     Connect with Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com     Key Takeaway “Your endocannabinoid system isn't just a biology lesson — it's a bridge between your body and the universe. When you feed it light, breath, and truth, you remember what balance actually feels like.”

We've all heard mitochondria called the "powerhouse of the cell," but what does that mean for skin? In this episode of The Rogue Pharmacist, Ben Fuchs breaks down how mitochondria fuel cell repair, collagen production, and overall skin vitality. Associated Skin Care Professionals (ASCP) presents The Rogue Pharmacist with Benjamin Knight Fuchs, R.Ph. This podcast takes an enlightening approach to supporting licensed estheticians in their pursuit to achieve results-driven skin care treatments for their clients. You can always count on us to share professional skin care education, innovative techniques, and the latest in skin science. Benjamin Knight Fuchs is a registered pharmacist, nutritionist, and skin care chemist with 35 years of experience developing pharmacy-potent skin health products for estheticians, dermatologists, and plastic surgeons. Ben's expert advice gives licensed estheticians the education and skin science to better support the skin care services performed in the treatment room while sharing insights to enhance clients' at-home skin care routines. Connect with Ben Fuchs: Website: www.brightsideben.com Phone: 844-236-6010 Facebook: www.facebook.com/The-Bright-Side-with-Pharmacist-Ben-Fuchs-101162801334696/ About Our Sponsor: All Truth Treatment Systems products have one thing in common—they work! Our products are made with 100 percent active and functional ingredients that make a difference to your skin. No fillers, preservatives, waxes, emulsifiers, oils, or fragrances. Our ingredients leverage the latest biochemical understandings and use proven strategies gleaned from years of compounding prescription skin health products for the most discerning physicians and patients. Website: www.TruthTreatmentsPro.com Facebook: www.facebook.com/truthtreatments Private Facebook Pro Group: www.facebook.com/groups/truthtreatments Instagram: http://www.instagram.com/truth.treatments

EPOC Explained: The Afterburn Effect That Boosts Metabolism and MitochondriaClick On My Website Below To Schedule A Free 15 Min Zoom Call:www.Over40FitnessHacks.comOver 40 Fitness Hacks SKOOL Group!Get Your Whoop4.0 Here!Episode Summary: Boosting Energy and Mitochondria Efficiency with HIT and EPOCIn this episode of Over 40 Fitness Hacks, host Brad Williams dives deep into how High-Intensity Training (HIT) and Excess Post-Exercise Oxygen Consumption (EPOC) can reignite energy levels, boost metabolism, and increase mitochondrial efficiency—especially important for those of us over 40.After recovering from hernia surgery, Brad shares his experience noticing a drop in calorie burn and energy output on his Whoop tracker. He explains how this decline connected to reduced mitochondrial activity from skipping HIT sessions. Turning to ChatGPT for insights, Brad explores how HIT stimulates mitochondrial biogenesis—the process of creating new mitochondria—by pushing the body to oxygen debt and triggering powerful recovery processes afterward.He breaks down the “afterburn effect” (EPOC), explaining how intense bursts of effort force the body to consume extra oxygen post-workout to restore balance, repair tissue, and boost metabolism for up to 36 hours. Brad also compares Zone 2 cardio (steady-state fat burning) with Zone 5 HIT (maximum heart rate, short bursts) and why both are crucial for longevity and efficiency.Listeners will learn:How HIT drives more calorie burn and mitochondrial density than slower workouts.The science behind EPOC and why it's a key to sustained fat loss.How to structure HIT for maximum efficiency (e.g., 30 seconds all-out, 90 seconds rest).Why adding weights or masks during HIT can actually reduce heart rate and efficiency.The importance of balancing intensity with recovery to avoid cortisol spikes and fatigue.Brad wraps up by sharing his plan to reintroduce weekly HIT sessions—short, bodyweight-based, and focused purely on speed and heart rate—to reignite energy and optimize his mitochondria naturally before turning back to supplements.

www.homehope.orgTroscriptionsChapters00:00 Foundations of Health Optimization03:00 The Role of Mitochondria in Mental Health05:49 A Multi-Pronged Approach to Healing08:48 Salutogenesis: Focusing on Health, Not Disease12:11 The Concept of Holobiont and Health Optimization15:02 Optimizing Health Span vs. Longevity18:02 Self-Triage for Health Improvement20:59 Basic Pillars of Health25:46 Addressing Snoring and Sleep Health26:59 The Importance of Grounding and Sun Exposure28:28 Understanding the Information Gap in Health30:19 Empowerment Through Personal Health Data32:28 The Role of Laboratory Testing in Health Optimization33:45 The Impact of Gut Health on Mental Well-being35:58 Exploring the Benefits of Mushrooms39:50 Natural vs. Synthetic Health Solutions42:13 The Balance of Optimization and Acceptance49:38 Community and Support in Health Journeys To learn more about Mission 22's impact and programs, visit www.mission22.org or find us on social media. IG: @mission_22. Tiktok: @_mission22

Beat BLOAT & unlock better protein absorption and digestion with MassZymes by BiOptimizers. NOW GET 15% off your order with the code VANESSA at bioptimizers.com/vanessa What separates people who keep fat off from those who regain it? In this episode, Vanessa Spina breaks down the latest research on long-term fat loss maintenance — including insights from one of the world's most respected obesity and metabolism researchers, Dr. James Hill. You'll learn the proven strategies that help preserve lean muscle, protect metabolism, and create sustainable fat loss — all backed by decades of science. Vanessa unpacks Dr. Hill's three-bucket model for lasting success, showing how to combine nutrition, activity, and mindset into a lifelong blueprint for body recomposition and metabolic health. Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa In this episode, you'll discover: • Why losing fat and keeping it off require two completely different skill sets • The research-backed protein and training strategies that preserve lean muscle • How small daily changes — like 100 fewer calories or 2,000 more steps — compound over time • Why exercise “fixes” your metabolism and helps you stay lean for life • The concept of your appetite sweet spot — and how to find it • How to shift from a “victim” to “voyager” mindset and make maintenance effortless • Dr. Hill's insights on GLP-1 medications and how to transition off without regaining weight If you've ever lost weight and struggled to maintain it, this episode will show you the science of what truly works — and how to protect your lean mass, metabolism, and confidence for the long term. Get my free NEW high-protein keto guide: The Keto Reset eBook Learn more about the TONE LUX Crystal red light therapy mask and the accessory the TONE LUX CONTOUR for the neck and décolleté and get 20% OFF with the code VANESSA Free high-protein keto guide: The Keto Reset eBook

In this episode of the Smarter Not Harder Podcast, the HOMeHOPe Faculty — Dr. Ted Achacoso, Dr. Scott Sherr, Jodi Duval, and Dr. Allen Bookatz — gather for an eye-opening and deeply personal roundtable on the real impact of small lifestyle changes. From hydration to circadian biology, sleep divorces to grayscale screens, this episode breaks down the science behind everyday habits that create extraordinary transformation. Join us as we delve into: Why hydration timing may matter more than hydration amount How “sleep divorces” saved marriages and improved HRV When working out less leads to more energy and fat loss The grayscale phone hack that reclaims your dopamine and your sleep  This episode is for you if: You think lifestyle change has to be hard, expensive, or dramatic You're curious why patients resist the simplest habits — and how to get them to comply You've tried “healthy” changes and wondered why they didn't work You're ready to fall in love with feeling well — and want to help others do the same You can also find this episode on…YouTube: https://youtu.be/KVRtjQ9pCgE Find more from Smarter Not Harder:Website: https://troscriptions.com/pages/podcast Instagram: https://instagram.com/troscriptions Get 10% Off your purchase of the Metabolomics Module by using *PODCAST10* at https://homehope.org Get 10% Off your Troscriptions purchase by using *POD10* at https://troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

Dr. Dan Pardi is the Chief Health Officer at Qualia Life Sciences, where he leads education initiatives focused on advancing healthspan and optimizing peak performance. Qualia Life Sciences develops products rooted in complex systems science, a framework that recognizes the body's natural ability to self-regulate and heal. Their growing product line includes support for brain health, cellular health, NAD+ levels, and most recently, Stem Cells.Dr. Pardi holds a PhD in Cognitive Neuroscience from Leiden University and Stanford. His work is dedicated to translating cutting-edge scientific research into practical tools and programs that help people live longer, healthier, and higher-performing lives. SHOWNOTES:

In this episode, we explore the connections between Autism and Parkinson's, focusing particularly on the basal ganglia and its substructures, notably the substantia nigra within the midbrain. We discuss how the substantia nigra, known for its high concentration of neuromelanin, plays a critical role in these disorders. The episode examines how neuromelanin, a dark pigment, not only absorbs all frequencies of light but also has antioxidant properties, binds metals, and acts as a neuroprotector. This discussion leads into the broader implications of environmental signals, particularly light, on human biology, touching on how modern changes in light exposure might affect these conditions.We examine the role of tyrosine in the synthesis of neuromelanin and its derivatives like dopamine, which are crucial for neural function. We look at how deficiencies or imbalances in these pathways could lead to the symptoms observed in Autism and Parkinson's, including motor function issues. The conversation also covers the direct and indirect pathways in the basal ganglia, explaining how these pathways facilitate or inhibit movement, respectively, and how their dysfunction can manifest in the characteristic motor symptoms of both disorders. We also touch on the significance of thyroid function, particularly the roles of T3 and T4 hormones, in brain development and neuron health, tying these elements back to the overarching theme of energy loss and transduction in both Autism and Parkinson's.Autism and Parkinson's are a lack of, or a loss of, energy.Biological Energy: Quantum Mechanisms, Water, DHA, and NF-kB: https://youtu.be/2-IA_gunXbwDaylight Computer Company, use "autism" for $50 off athttps://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount athttps://getchroma.co/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount athttps://thecognity.com0:00 Autism and Parkinson's; Basal Ganglia; Substantia Nigra; Neuromelanin; Internal Calculators2:15 Tyrosine; Chromophores; Aromatic Amino Acids3:50 Biological Energy; Mitochondria; Environmental Signals; Cytochrome C Oxidase; Autism Research Miss6:20 Deep Brain Stimulation6:48 Neuromelanin9:02 Reverse Engineer ATPase10:48 Tree Examples11:45 Hypoxia and loss of energy & dopamine12:26 Eyes, hair, & skin; RPE; efficiency & power; What is Light?13:58 Light; Information & Energy; electromagnetic; wave-particle duality; sunlight versus artificial light17:08 Thyroid; T3 & T4; Iodine18:31 Roles of T323:00 Loss of energy in the womb & Autism research25:00 Melanin + Water = Electrons26:40 Basal Ganglia; "Motivations" & Movements; Direct Pathway30:55 Indirect Pathway32:52 Go, No-Go; Action selection, learning & habits; fine motor skills34:18 Parkinson's and loss of timing & energy; modulating the two pathways & dopamine37:07 Reviews/Ratings & contact infoX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

Modern joint pain isn't just wear and tear—it's a systemic, metabolic disease that starts years before symptoms show. In this episode, you'll learn how inflammation, mitochondria dysfunction, and immune imbalance trigger cartilage loss… and how to reverse it using targeted cytokine modulation, cellular regeneration, and smarter supplements for longevity and human performance. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Kiran Krishnan, a research microbiologist and Chief Scientific Officer at Calroy Health Sciences. He's the founder of Microbiome Labs—one of the most trusted microbiome-focused brands in functional medicine—and a formulator behind cutting-edge supplements like Arterosil and Vascanox. With over two decades of experience, Kiran has launched multiple health ventures, authored scientific textbook chapters, published clinical trials, and holds global patents in human health. He's a leading authority on systemic inflammation, mitochondrial dysfunction, and gut-driven disease—and one of the few voices making complex biology accessible for real-world results. He breaks down their new supplement Cartigenix HP, and how cytokines like IL-6 and TNF-alpha flip your cartilage cells from anabolic repair to catabolic destruction, how mitochondrial decline speeds up joint damage, and why most modern painkillers make your joints worse. You'll learn how a specialized blend of boswellia and celery seed reprograms inflammation, why walking beats medication in clinical trials, and how fasting, nitric oxide, and gut health work together to optimize joint regeneration. You'll learn: • How cartilage cells (chondrocytes) rely on mitochondria for tissue repair • Why global cytokines like IL-6 and TNF-alpha drive joint degradation and brain fog • How cartilage begins to break down in your teens—and what to do about it now • The surprising clinical data on walking distance, inflammation markers, and recovery • Why most supplements and NSAIDs fail—and what actually rebuilds joints • How diet and leaky gut create 5-day inflammation spikes from a single fast-food meal • The mitochondrial link between joint pain, cardiovascular risk, and depression • Why perimenopausal women are at 10x higher risk for arthritis—and how to prevent it • How to track your biological joint age using imaging and systemic inflammation labs This is essential listening for anyone serious about biohacking, functional medicine, pain-free aging, and human performance. Whether you're lifting heavy, walking daily, or just trying to stay mobile into old age, this episode gives you the science and tools to reverse joint degeneration and extend your healthspan. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Joint cartilage regeneration, IL-6 inflammation suppression, TNF-alpha cytokine modulation, Chondrocyte mitochondrial repair, Catabolic to anabolic tissue shift, Osteoarthritis reversal, Rheumatoid arthritis inflammation, Mitochondria and collagen synthesis, Boswellia seratol extract, Celery seed COX inhibition, Matrix metalloproteinase (MMP) inhibition, Synovial fluid inflammation, Leaky gut and joint pain, Six-minute walk test improvement, Global cytokine markers, High sensitivity CRP reduction, ESR sedimentation rate, Uric acid crystal formation, Post-prandial glucose walking, Cartilage MRI biomarkers, Functional medicine joint support, Fasted repair stacking, Vasodilation and nitric oxide, Anti-inflammatory supplement stacking, NF-kB pathway reduction, Joint space biological age, Microvascular circulation and cartilage, Caloric load and cytokine spike, Perimenopause and arthritis risk, Joint tissue anabolic activation **Get an exclusive discount for podcast listeners at calroy.com/dave : https://calroy.com/product/cartigenix-hp/?lp=dave ** Thank you to our sponsors! -BodyGuardz | Visit https://www.bodyguardz.com/ and use code DAVE for 25% off. -BiOptimizers | Go to http://bioptimizers.com/dave and use code DAVE15 to get 15% off your order. -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. -Caldera + Lab | Go to https://calderalab.com/DAVE and use code DAVE at checkout for 20% off your first order. Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:25 — Introduction 2:01 — Why Modern Medicine Fails at Joint Pain 3:07 — Painkillers That Accelerate Joint Damage 7:35 — Rheumatoid vs. Osteoarthritis Explained 8:54 — Cytokines That Destroy Cartilage 12:10 — Arthritis Begins in Your Teens 15:35 — 75% Pain Reduction in 7 Days 18:35 — The Science Behind Boswellia & Celery Seed 24:10 — Six-Minute Walk Test Results 25:45 — The $200/Month Painkiller Trap 28:53 — Proof Cartilage Can Regrow 31:01 — Mitochondria and Joint Repair 32:29 — Inflammation Links to Heart Disease 35:52 — Why Glucosamine Doesn't Work 37:07 — Silent Arthritis in 90% of Adults 40:44 — Why Women Face Higher Joint Risk After 40 45:52 — Food as the #1 Inflammation Trigger 47:23 — Fasting & Cartogenics Stack for Repair 50:27 — Movement Snacks and Efficient Training 55:54 — Why Joints Heal Slower Than Muscles 57:48 — Dave's Stack and Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This week on Optimal Metabolism, Shana sits down with one of her greatest mentors in circadian and quantum biology, Carrie Bennett, to uncover the surprising science behind winter wellness. Together, they explore why embracing the dark may be the key to restoring your melatonin rhythm, healing adrenal fatigue, and boosting mitochondrial health this season. You'll learn how our biology shifts during winter, why being more ketogenic and aligned with shorter days supports metabolic healing, and whether we really need to supplement with vitamin D—or if nature already built the answer into the circadian rhythm itself. If you've been feeling sluggish, anxious, or out of sync this winter, this episode will help you reconnect to the light and dark rhythms God designed for your energy, hormones, and overall wellness. What You'll Learn ✨ How embracing darkness boosts melatonin and repairs circadian rhythm ✨ Why longer nights are not a problem to fix—but a healing signal for the body ✨ The link between mitochondrial water, light exposure, and adrenal recovery ✨ Why going more ketogenic in winter can enhance energy and fat-burning ✨ The truth about vitamin D supplementation during darker months ✨ How meal timing and grounding restore cortisol and hormonal balance ✨ Carrie's top practical steps to live in sync with natural light cycles Links & Resources

Chris Burres is a published author of Live Longer and Better, Host of the Live Beyond the Norms, Podcast and patent holder with a surprising twist – he's not just a visionary scientist but also a master of comedy improv. Chris Burres is the founder and chief scientist at MyVitalC, where he manufactures a Nobel Prize winning molecule responsible for the single longest longevity experimental result in history, a full 90% extension of life.  He is the intersection where science meets laughter, and his life's mission is to help people live longer, healthier, happier, pain-free lives with science. Follow Chris on Social Media: https://www.instagram.com/myvitalc https://www.instagram.com/chrisburres https://www.tiktok.com/@myvitalc https://www.youtube.com/@MyVitalC/videos Additional Resources:

NEW! Support your strength and muscle goals with PUORI Creatine+ — a clean, effective creatine monohydrate supplement enhanced with taurine. Get 20% off at puori.com/VANESSA In today's episode, Vanessa sits down with one of the most influential figures in obesity and metabolism research — Dr. James Hill, Professor of Nutrition Sciences at the University of Alabama at Birmingham and co-founder of the National Weight Control Registry. Dr. Hill has spent over four decades studying how people successfully lose weight, maintain it long-term, and preserve their lean mass and metabolic health. Dr. Hill has led landmark clinical trials such as the Diabetes Prevention Program, Look AHEAD, and the Beef WISE Study on high-protein diets. His decades of work reveal why weight loss is only the beginning — and why the real secret to success lies in learning the completely different skill set of maintenance. OneSkin is powered by the breakthrough peptide OS-01, the first ingredient proven to reduce skin's biological age. I use the OS-01 Face and Eye formulas daily—they've transformed my skin's smoothness, firmness, and glow. Visit oneskin.co/VANESSA and use code VANESSA for 15% off your first purchase In this conversation, you'll hear: The protein “lever” Dr. Hill uses to curb appetite and protect muscle during a cut—plus why the source may matter less than you think Three habits most long-term maintainers share (and one that surprised even him) The moment your “diet” must flip into “maintenance”—and a simple sign you're ready The smallest daily tweak from his research that predicts whether you'll regain or not What exercise actually changes in your metabolism beyond calorie burn—and how much you really need The simple resistance-training + protein formula he gives midlife women to keep muscle while losing fat His three-bucket framework (diet, activity, mind state) and a 60-second self-check to find which bucket is breaking your results The mindset shift that moves people from “I always regain” to “this is who I am” — plus a quick exercise to uncover your real why The step-by-step exit plan he uses when patients come off GLP-1s—starting with what to do in week one to avoid rebound If you've ever lost weight and struggled to keep it off, this episode shows you which levers matter most—and how to pull them so your results stick while your metabolism and muscle thrive. Get delicious high protein meal recipes! Connect with Vanessa on Instagram @ketogenicgirl Free High-Protein Keto Guide  Get 20% off on the Tone LUX Crystal Red Light Therapy Mask or the Tone Device breath ketone analyzer at https://ketogenicgirl.com with the code VANESSA Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast Mentioned in this episode: • Dr. James Hill's upcoming book: Losing the Weight Loss Meds: A 10-Week Playbook for Stopping GLP-1 Medications and Keeping the Weight Off — now available for pre-order • The National Weight Control Registry; The Diabetes Prevention Program (DPP); The Look AHEAD Study; The Beef WISE Study The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.

In this illuminating episode, we sit down with Dr. Paul Barrattiero, founder of Echo Water, to explore how hydrogen-rich water can transform the gut and simplify the entire healing process. Our bodies are designed to produce hydrogen naturally, but thanks to stress, toxins, and modern diets, that ability often shuts down. Dr. Paul explains how drinking hydrogen water helps restore this missing function — changing the electrical voltage of the gut and signaling the body to repair itself.Dr. Paul Barrattiero is a pioneering advocate for molecular hydrogen therapy with over two decades of experience in the health and wellness industry. As the founder of Echo Water, he has also held C-level executive positions at prominent wellness companies. His career is marked by a commitment to advancing the benefits of hydrogen therapy and holistic health solutions. Paul created the Echo Water Hydrogen System designed to harness the power of hydrogen water to reduce oxidative stress and inflammation—key contributors to many chronic diseases. Echo Water now offers a range of products dedicated to supporting detoxification, cognitive function, immune health, and gut recovery. In addition to his work with Echo Water, Paul is also the visionary behind LumaNova, a groundbreaking company focused on light therapy for wellness. With a range of products, including the LumaNova Vitamin D Light™, Paul is bringing scientifically backed light therapy into homes and wellness centers. LumaNova's mission is to help individuals improve mood, sleep, and overall well-being by tapping into the regenerative power of light—one of the most effective, natural tools for improving health and vitality. SHOW NOTES:0:40 Welcome to the podcast!3:45 Dr. Paul Barratiero's Bio4:52 Welcome him to the show!5:51 What's new in hydrogen research?7:33 Benefits of new Echo flask8:32 Difference between hydrogen & regular water11:58 Humid & fulvic acids vs hydrogen13:06 How to fix gut issues 17:45 Do we need hydrogen forever?19:04 Vitamin D & Red light21:24 Mitochondria & athletic recovery26:24 What kind of water to put in Echo30:53 Eating in Italy vs US34:56 Quality of hydrogen products39:06 Hydrogen prebiotic mix43:08 Echo water products48:24 Hydrogen as an antioxidant signal50:36 H. Pylori & SIBO52:08 Fasting with hydrogen54:43 Hydrogen & menstrual cycle issues57:32 Studies on female hormones58:59 Testosterone and weight gain1:00:05 Echo hydrogen bath unit1:05:40 His finale piece of advice1:07:59 Thanks for tuning in!RESOURCES:Website: echowater.com - Save 10% with code: BIOHACKERBABESInstagramFacebookTikTokTwitterYouTubeSupport this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands

New options for knee pain—radiation and embolization; Popeye was right to power-up with spinach; Conquering inflammation; Methane-predominant SIBO; Unnecessary back surgery on seniors is rampant; Medicare Advantage patients often relegated to inferior cancer surgery. 

Biohacking isn't just food + exercise, it's about fixing the invisible disruptors wrecking your biology. EMFs, mold, toxins, mitochondrial stress, these are the real reasons you still feel tired, foggy, or inflamed even on a perfect diet. I've been there. I lost 100 lbs, built Bulletproof Coffee, and discovered why food alone isn't enough. In this video, I'll show you what's actually holding back your energy, focus, and longevity… and how to finally feel truly bulletproof.Chapters:0:00 – Introduction1:30 – The hidden disruptors wrecking your health2:15 – EMFs: invisible energy thieves3:00 – Mold exposure: the silent killer in your home4:00 – How toxins block your nutrients5:10 – Mitochondria: the real source of energy6:20 – Detox hacks that actually work7:30 – Binders: the secret to flushing toxins8:30 – Rebuilding nutrients for lasting energy9:20 – The missing biological switch: nervous system safety10:30 – Resetting your circadian rhythm naturally11:30 – Box breathing: a biohack for instant calm12:20 – Gratitude, digestion & unlocking thrival modeConnect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/Danger Coffee: https://dangercoffee.com/DAVE15Dave Asprey's BEYOND Conference: https://beyondconference.com/Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15Upgrade Collective: https://www.ourupgradecollective.comUpgrade Labs: https://upgradelabs.com40 Years of Zen: https://40yearsofzen.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode, Angela sits down with Ulrich Dempfle, co-founder and CEO of CAROL Bike, to uncover the science and innovation behind one of the most time-efficient ways to boost VO₂ max, metabolic health, and brain function. Ulrich explains why VO₂ max is the most important marker for longevity, how it declines without training, and how short, AI-guided REHIT sprints boost mitochondria, BDNF (brain-derived neurotrophic factor), and cardiovascular fitness in just minutes. He also breaks down how Reduced-Exertion High-Intensity Interval Training (REHIT) works, why traditional zone 2 training doesn't work for everyone, and how gamification and real-time performance data make staying consistent easier than ever. What You'll Learn: Why VO₂ max is the strongest predictor of health and longevity How REHIT delivers major fitness gains in just minutes Why zone 2 training doesn't work for everyone How short, AI-guided sprints boost mitochondria and brain function Metabolic and cognitive benefits of REHIT How CAROL Bike personalises training to maximise VO₂ max TIMESTAMPS 00:00 Intro & The Importance of VO₂ Max 01:00 How VO₂ Max Declines and Why It Matters 04:22 Zone 2 Training Myths & Non-Responders 09:09 Mitochondria 101: Density vs. Efficiency 12:00 The Science Behind REHIT & CAROL Bike 19:09 Gamification, Dopamine & Workout Adherence 22:02 Lactate, BDNF & Brain Health Benefits 26:04 Insulin Sensitivity & Metabolic Effects 30:17 Efficient Weekly Training Structure 34:51 Afterburn Effect & Fat Oxidation Misconceptions 45:00 VO₂ Max Testing & Fitness Score Tracking 52:00 Peer-Reviewed Research & AI Personalisation 57:30 Real-World VO₂ Max Improvements 1:01:00 How to Get Started & Special Listener Offer VALUABLE RESOURCES ⁠Join The High Performance Health Community⁠ ⁠Click here⁠ for discounts on all the products I personally use and recommend A BIG thank you to our sponsors who make the show possible: Exclusive discount for podcast listeners on Carol Bike - the bike that gets you fittest the fastest - click here WWW.CAROLBIKE.COM and use code ANGELA Hormone Harmony - go to LVLUPHEALTH.COM/ANGELA and use the code ANGELA at checkout for an exclusive 15% off ABOUT THE GUEST Ulrich Dempfle is the CEO and co-founder of CAROL Bike, the world's first Reduced Exertion HIIT (REHIT) exercise bike. Originally trained as a mechanical engineer in Germany, Ulrich began his career in the automotive industry before moving to the UK to pioneer AI in healthcare systems. After discovering REHIT through a BBC documentary, he partnered with leading exercise scientists to bring this lab-based protocol to the public. Today, Ulrich leads CAROL's product development, combining science, data, and technology to deliver the most time-efficient cardio workout. CAROL website: https://carolbike.com/ Find CAROL Bike on all platforms @theCAROLbike ABOUT THE HOST Angela Foster is an award-winning Nutritionist, Health & Performance Coach, Speaker, and Host of the High Performance Health podcast. A former Corporate lawyer turned industry leader in biohacking and health optimisation for women, Angela has been featured in Huff Post, Runners World, The Health Optimisation Summit, BrainTap, The Women's Biohacking Conference, Livestrong & Natural Health Magazine. Angela is the creator of BioSyncing®️, a blueprint for ambitious entrepreneurial women to biohack their health so they can 10X how they show up in their business and family without burning out. DISCLAIMER The High Performance Health Podcast is for general information purposes only and does not constitute professional or coaching advice, nor does it form a client relationship. The use of information on this podcast, or materials linked from this podcast, is at the user's own risk. Always seek advice from your medical doctor or healthcare professional before implementing any changes.

Beat BLOAT & unlock better protein absorption and digestion with MassZymes by BiOptimizers. NOW GET 15% off your order with the code VANESSA at bioptimizers.com/vanessa In this solo episode, Vanessa breaks down her in-depth conversation with Dr. Emily Lantz, a leading researcher in protein metabolism and muscle physiology. Discover why eating around 30 g of high-quality protein at each meal may be the key to preserving lean muscle, optimizing metabolism, and aging stronger—especially for women through perimenopause and beyond. Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa Vanessa also unpacks the research on protein distribution (30-30-30), sleep as an anabolic signal, and how to protect your muscle during rapid fat loss, translating cutting-edge science into practical steps you can use today. What You'll Learn The science behind the 30-30-30 protein rule and why it matters for women How sleep loss can lower muscle protein synthesis by up to 20% What studies reveal about plant vs. animal protein for glucose control and satiety The truth about “wasted” protein and how much you really need per meal How to minimize muscle loss during fat loss or menopause A simple 3-meal template to optimize body composition and strength

Back from Metabolic Health Day, I'm joined by client and Terrain Advocate-in-training, Katie Resor, to share the most use-today insights: energy and fatigue through a metabolic lens, nature and circadian rhythm, simple detox wins, EMF practices that fit real life, and the vendors/tests we loved. You'll also hear reflections on community, hope, and why health is a terrain we tend—not a finish line. Show links include the conference recordings and resources we mention.   Explore more support: Grab your copy of the Metabolic Health Day conference recordings here: https://mtih.app.neoncrm.com/np/clients/mtih/product.jsp?product=1&https://www.thebreastcancerrecoverycoach.com/metabolic-health-coaching-m Better Than Before Breast Cancer Life Coaching Membership: https://www.thebreastcancerrecoverycoach.com/lifecoaching   Let's Connect! If this episode helped you breathe a little easier, please share it with a friend or leave a review. Every share helps spread this message of hope, healing, and whole-person wellness.

I sat down with R. Blank, CEO of Shield Your Body and author of Empowered, to cut through the EMF noise with clear science and practical steps. If you've ever wondered what EMF actually is, what's hype vs. real risk, and how to reduce exposure without abandoning modern tech, this conversation is for you.R. breaks down ionizing vs. non-ionizing radiation, why your cell phone is the #1 avoidable source, and the “distance × time” rule that drives smarter habits. We get tactical: building a low-EMF bedroom (no phones, battery-powered alarm clocks, low-blue rechargeable lamps), why a meter beats guesswork, when to de-energize a circuit at night, safer audio (air-tubes over AirPods), and how to configure your phone radios (airplane mode, Wi-Fi/Bluetooth off when you don't need them). We also compare shielding products vs. Faraday gear, when apparel makes sense (travel and high-density environments), and how to think about privacy tools like Faraday wallets and laptop sleeves.If you want data-backed, low-friction ways to protect sleep, focus, and long-term health without quitting your devices, you'll love this one. You'll walk away with a simple rule (“stop carrying your phone in your pocket”), a bedroom checklist, and a clearer map for what to change today and what, if anything, to buy later.Timeline Mitopure Gummies: GET 20% Off Now!

Have you heard all the hype around Urolithin A?  In this episode, I sit down with expert integrative and functional nutritionist, Jennifer Scheinman, to dive into one of the most exciting breakthroughs in women's health and longevity—Urolithin A.  This little-known yet well-researched natural molecule has been shown in studies to significantly improve muscle strength and function, helping combat the age-related muscle decline so many of us experience in midlife.  We'll unpack how Urolithin A supports mitochondrial health—the very core of our energy production—so you can feel more vibrant and strong at every stage.  Plus, Jennifer shares how topical Urolithin A can even target the internal and external signs of skin aging, giving your skin and cells a rejuvenating boost.  Ready to feel vibrant, strong, and glow from the inside out? Tune in here to feel truly energized from the cellular level up! Jennifer Scheinman Jennifer Scheinman is a Registered Dietitian Nutritionist with over 25 years of experience in nutrition and wellness. She holds a master's degree in integrative and functional nutrition, and has advanced training from the Institute of Functional Medicine. Jen's expertise in cellular health and aging makes her a sought-after speaker and media expert. She's the Senior Manager of Nutrition Affairs at Timeline, where she educates healthcare providers and consumers on the role of Urolithin A in supporting mitochondrial health and longevity. Beyond Timeline, Jen is a writer, speaker, and nutrition coach, helping women optimize their health and vitality during menopause and beyond. IN THIS EPISODE What's happening to women's mitochondria with age  How declining hormones play a role in energy and appearance  Ways to optimize cellular function in midlife  Supplementing with Urolithin A, and how it helps your body  Research findings on Urolithin A and muscle health  Different forms of Urolithin A supplementation for your lifestyle  How topical application of Urolithin A helps your skin  Where and how to get your Mitopure (Urolithin A) with 20% off! QUOTES “Other things we saw in that study were improvements in things like inflammatory markers, which we know chronic inflammation is a huge issue as we start to get older. We saw specifically C-reactive protein was lowered, and we saw other markers of muscle health that, while they didn't make statistical significance, they were trending that way.” “It stays very potent and very localized– a benefit to the skin. So you're having that same cellular turnover of the mitochondria, basically making the mitochondria in your skin act in a more youthful way.” “Even just after 2 weeks, we start to see improvements that are visibly noticeable. And then when we take that out to 8 weeks, it's statistically significant improvements in wrinkle reduction and in wrinkle depth. So, [it's] really powerful but gentle.” RESOURCES MENTIONED Get your free VIP ticket to the Perimenopause Solution event https://hayh.site/pr_bl_ap-snyder_a_snyder Order Mitopure (Urolithin A) at Timeline HERE with discount code ENERGIZED for 20% off your purchase!  https://⁠timeline.com/ENERGIZED Timeline on Instagram Jen Scheinman on Instagram  RELATED EPISODES  663: From Wired and Tired to Calm and Energized: The GABA-Mitochondria Connection + How to Fix It at the Cellular Level with Dr. Scott Sherr #653: Mitochondria, Menopause & Metabolism: The Cellular Secret to More Energy After 40 with Dr. Felice Gersh #623: Red Light Therapy for Upgrading Your Mitochondria, Cellular Energy, Skin and Brain Health with Jonathan Otto 595: How to Master Your Metabolism and Reverse Cellular Aging in Midlife + My Best Tips to Thrive with Dr. Mariza

In this masterclass episode of Skin Anarchy, Dr. Ekta Yadav sits down with Dr. Julie Faitg, Senior Manager of Applied Research and Regulatory Affairs at Timeline, to uncover how mitochondrial science is transforming the future of skin longevity.Dr. Feitge challenges the familiar “powerhouse” analogy, instead calling mitochondria the “CEO of the cell.” Far from passive energy producers, these organelles orchestrate communication, repair, and renewal—directly influencing collagen production, elasticity, and cellular resilience. “If your mitochondria aren't healthy,” she explains, “the entire cascade of cellular function begins to falter.”Through vivid analogies, Dr. Feitge describes how mitochondria behave differently across tissues—fueling endurance in muscles, focus in the brain, and regeneration in the skin. This adaptability, she notes, is what makes them the foundation of both vitality and longevity.The conversation dives into mitochondrial resilience, the skin's ability to repair and recover from stress. Aging begins when this resilience declines, leading to diminished energy, slower renewal, and visible signs of fatigue.Dr. Faitgd highlights Timeline's breakthrough ingredient, Mitopure® (Urolithin A)—a clinically validated compound that triggers mitophagy, the process of recycling damaged mitochondria. In trials, topical Mitopure® improved collagen expression, hydration, and firmness while reducing inflammation and UV-induced stress.Developed in Switzerland under rigorous safety and precision standards, Timeline's skincare line redefines beauty as m—a shift from treating the surface to revitalizing the source.

Longevity and anti-aging science has leveled up in recent years, and as a result, there are tons of game-changing treatments with proven effectiveness. From supplements to boost mitochondrial health to light and oxygen therapy, you can slow or even reverse aging as well as improve your overall health. Learn the top treatments for anti-aging – listen now!   ✅Start healing with us! Learn more about our virtual clinic:  https://drruscio.com/virtual-clinic/  

NEW! Support your strength and muscle goals with PUORI Creatine+ — a clean, effective creatine monohydrate supplement enhanced with magnesium and vitamin B12. Get 20% off at puori.com/VANESSA Can you really lose fat without losing muscle? Vanessa sits down with Dr. Guillermo Escalante, physique competitor and sports nutrition researcher, to reveal the science of doing exactly that. Learn how high-protein diets and refeeds can preserve lean mass, reignite a slowed metabolism, and make fat loss more sustainable. Dr. Escalante shares evidence-backed insights from his own research and contest experience on how to optimize protein intake, structure refeeds, and achieve real body recomposition—without the extremes. OneSkin is powered by the breakthrough peptide OS-01, the first ingredient proven to reduce skin's biological age. I use the OS-01 Face and Eye formulas daily—they've transformed my skin's smoothness, firmness, and glow. Visit oneskin.co/VANESSA and use code VANESSA for 15% off your first purchase Unlock sharper focus and support long-term brain health with Ketone-IQ—clean brain fuel for deep work, mental clarity, and sustained energy with no crash. Get 30% off your subscription, plus a free gift with your second shipment at Ketone.com/vanessa. Get delicious high protein meal recipes! Connect with Vanessa on Instagram @ketogenicgirl Free High-Protein Keto Guide  Get 20% off on the Tone LUX Crystal Red Light Therapy Mask or the Tone Device breath ketone analyzer at https://ketogenicgirl.com with the code VANESSA Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.

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“There isn't an aspect of our health that mitochondria don't affect,” explains Daria Mochly-Rosen, Ph.D.  Daria Mochly-Rosen, Ph.D., Stanford professor, renowned protein chemist, and author, joins us today to explain how mitochondria impact energy, resilience, and long-term health, and what practical steps we can take to support them:  - What is mitochondrial dysfunction (~3:15) - Bringing awareness to the field (~8:20) - Signs of mitochondrial dysfunction (~9:30) - The importance of mitochondria (~10:30) - Assessing mitochondrial health (~11:55) - How to improve cellular health (~13:45) - Diet & exercise for mitochondrial health (~17:30) - Cancer & mitochondria (~27:45) - Biohacking your cellular health (~34:40) - AI & genentics (~38:30) - Empowering health takeaways (~44:00) Referenced in the episode:  - Follow Mochly-Rosen online (https://www.linkedin.com/in/daria-mochly-rosen-9733bb198/)  - Pick up her book, The Life Machines  - Check out her company, SPARK NS (https://sparkns.org/)  This podcast was made in partnership with Gaia Herbs. Your path to stress support starts now.* Visit gaiaherbs.com and use promo code MBGPod to get 20% off. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.We hope you enjoy this episode, and feel free to watch the full video on YouTube! Whether it's an article or podcast, we want to know what we can do to help here at mindbodygreen. Let us know at: podcast@mindbodygreen.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

What if you could improve your mitochondria, oxygen efficiency, and recovery in just 20 minutes a day—by breathing energized water? This episode explores one of the most surprising breakthroughs in biohacking and how it can help you live longer, think clearer, and perform better. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey talks with Rowena Gates, co-founder of NanoVi, a therapeutic device backed by biophysics research that supports protein repair and mitochondrial communication. Her work reveals how structured water inside your cells drives neuroplasticity, cellular regeneration, and stress resilience—offering a new pathway to recovery, energy, and longevity. You'll learn how structured water affects mitochondrial efficiency, how it compares to recovery methods like cold therapy and fasting, and why improved VO₂ max may correlate with a longer lifespan. Dave and Rowena also explore how NanoVi stacks with supplements, nootropics, ketosis, and functional medicine to enhance brain optimization, metabolism, and human performance. You'll Learn: • How structured water boosts mitochondrial function and VO₂ max • The difference between hydration and energized cellular water • What happens to your brain and heart rate variability in 20 minutes of NanoVi use • The link between water structure, protein repair, and recovery • How biohackers combine NanoVi with fasting, cold therapy, and sleep optimization for faster results • Why stronger mitochondrial communication can extend lifespan and upgrade cognitive function They explore how structured water, mitochondrial repair, and recovery science intersect to create a smarter approach to health and longevity. You'll also learn how optimizing cellular communication, oxygen efficiency, and stress resilience can accelerate healing, improve focus, and extend lifespan. This is essential listening for anyone serious about biohacking, human performance, and longevity, and for those who want to understand how functional biology and mitochondrial science are redefining recovery, energy, and aging. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: NanoVi, Structured water, Energized water, Biohacking, Dave Asprey, Mitochondrial repair, Mitochondrial communication, Human performance, Longevity, Recovery science, Oxidative stress, Protein repair, Redox signaling, Cellular hydration, Functional medicine, VO₂ max, Neuroplasticity, Brain optimization, Cellular energy, Stress resilience, Cold therapy, Fasting, Sleep optimization, Breathwork, Nootropics, Metabolism, Oxygen efficiency, ATP production, Cellular regeneration, Anti-aging, Smarter Not Harder **To level up your mitochondria with a NanoVi: visit https://eng3corp.com/dave/ ** Resources: • Business of Biohacking Summit | Register to attend October 20-23 in Austin, TX https://businessofbiohacking.com/ • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:25 — Introduction to NanoVi 4:01 — How to Use NanoVi 6:23 — Understanding Ordered Water 9:16 — Scientific Evidence & Studies 13:02 — Pricing & Accessibility 15:02 — Mitochondrial Function & MiScreen Results 19:55 — Brain Function & Cognitive Benefits 23:47 — How Ordered Water Works 27:34 — Cellular Communication & Fascia 30:14 — Heart Rate Variability & Stress Reduction 34:54 — Athletic Performance & Recovery 38:52 — Mental Health & Sleep Benefits 42:00 — Supplement Stacking 45:50 — Deep Sleep & Parasympathetic State 48:48 — Chronic Conditions & Fatigue 51:54 — Meditation & Brain Training 55:42 — Brain Injury & Resilience 59:36 — Conclusion & Where to Get It See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this powerful educational episode, Vanessa sits down with Oliver Amdrup-Chamby, CEO and Co-Founder of Puori, for an in-depth masterclass on the supplements most overlooked—yet most transformative—for women's health: creatine and omega-3s. Drawing on the latest scientific research and insights from world-leading muscle and metabolism experts, Vanessa and Oliver unpack: ✅ Why creatine is a foundational supplement for women—supporting fat loss, body recomposition, muscle preservation, and cognition ✅ How creatine protects metabolism and lean mass during fat loss ✅ The truth about “water retention” and bloating myths ✅ How creatine supports menopause, bone density, and strength across the lifespan ✅ The emerging research on brain and mood benefits of creatine ✅ Why omega-3s are critical for inflammation, recovery, metabolic health, and brain function ✅ How creatine and omega-3s synergize for performance and longevity Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa Then, in the final third of the conversation, they address one of the most pressing issues in the supplement industry today: purity and contamination. Vanessa and Oliver discuss: ⚠️ Why heavy metals like lead have been found in popular protein powders and prenatal vitamins ⚠️ What “safe levels” actually mean ⚠️ How consumers can protect themselves by choosing transparent, third-party tested products ✅ How Puori leads the industry with Clean Label Project certification, testing for over 200 contaminants, and QR codes that let you view your batch's lab results instantly This episode is a must-listen for women who want to take their health, fat loss, and longevity to the next level—using the cleanest, most evidence-based supplements available. Beat BLOAT & unlock better protein absorption and digestion with MassZymes by BiOptimizers. NOW GET 15% off your order with the code VANESSA at bioptimizers.com/vanessa Mentioned in This Episode: • Puori Creatine+ — use code VANESSA for 20% off, including subscriptions • Creatine Supplementation in Women's Health: A Lifespan Perspective • Puori Omega-3 testing & Clean Label certification Get my NEW high-protein keto guide: The Keto Reset eBook Learn more about the TONE LUX Crystal red light therapy mask and the accessory the TONE LUX CONTOUR for the neck and décolleté and get 20% OFF with the code VANESSA Free high-protein keto guide: The Keto Reset eBook