Podcasts about mitochondria

The fascinating intersections of circadian biology, quantum health, and women's wellness really come alive as I sit down with Neurosurgeon-turned-Quantum-Biologist Dr. Jack Kruse. You'll hear how simple things, like the light you see first thing in the morning, quietly shape your hormones, energy, and even how you age. Dr. Jack's decades of surgical and biophysical knowledge make these concepts surprisingly practical for everyday health. By the end, you may find yourself rethinking your daily routines in the best way.   Together, we get into why AM sunlight can make such a big difference for women going through hormonal changes, especially around menopause. Dr. Jack breaks down big ideas like heteroplasmy in simple, eye-opening terms and shows how it plays into skin health, longevity, and mitochondrial function. You'll also hear why red light deserves a place in your wellness routine, and how blue light and non-native EMFs might be draining more than just your battery.   If you've ever struggled with weight changes, low energy, or hormonal shifts, you'll appreciate Dr. Jack's explanation of the leptin-melanocortin pathway and what it means for women at every age. His own 150-pound weight-loss story adds real heart to the science and shows how much can change when your environment starts working for you instead of against you. This episode delivers a mix of empowering insights and simple shifts you can start today for better vitality.   And before you go, make sure to download my Free Holiday Recipe Guide, a delicious, hormone-friendly way to enjoy festive, Keto-Green dishes all season long at dranna.com.   Key Timestamps: [00:00:00] Introduction. [00:04:57] Circadian biology and health optimization. [00:10:10] The importance of morning sunlight. [00:17:00] Environmental impact on women's health. [00:19:54] Blue light toxicity in eyes. [00:23:04] Impact of sunglasses on health. [00:27:52] Importance of oxytocin hormone. [00:30:30] Mitochondria and light absorption. [00:36:15] Leptin and fertility connection. [00:38:05] Importance of fat for babies. [00:43:05] Blue light's role in hormonal balance and infertility. [00:45:36] Natural sun protection alternatives. [00:50:32] Hormonal health and technology impact. [00:53:10] Light as medicine and healing. [00:58:41] GABA and benzodiazepine addiction. [01:00:06] Relationship between light and health. [01:09:18] Deuterium's impact on health. [01:13:39] Sun exposure for sexual health. [01:20:34] Politics and health care challenges. [01:24:03] Importance of time over wealth. [01:27:29] Jet lag management strategies.   Memorable Quotes: "If you're a woman who's a dried-up prune, this by definition already tells you that you don't get enough AM sunlight." [00:10:17] – Dr. Jack Kruse   "Blue light is the single number one thing that destroys hormone balance." [00:43:21] – Dr. Jack Kruse   Links Mentioned: Free Holiday Recipe Guide: https://dranna.com/holidayrecipes   Connect with Dr. Jack Kruse: Website: https://jackkruse.com/ Instagram: https://www.instagram.com/drjackkruse/ Facebook: https://www.facebook.com/drjackkruse/ Patreon: https://www.patreon.com/drjackkruse   Connect with Dr. Anna Cabeca: Website: https://drannacabeca.com/pages/show Instagram: https://www.instagram.com/thegirlfrienddoctor/ YouTube: https://www.youtube.com/@thegirlfrienddoctor TikTok: https://www.tiktok.com/@drannacabeca   Produced by Evolved Podcasting: www.evolvedpodcasting.com

Today, I'm joined by the brilliant Dr. Elena Gross, a neuroscientist with an inspiring story and a relentless drive to solve the mysteries behind chronic migraines and brain health. Dr. Gross's personal journey—enduring twenty days of migraine each month and navigating countless failed treatments—led her from crawling through the pain to founding Brain Ritual, a company reimagining brain fuel for longevity.   Episode Timestamps: Intro and offers ... 00:00:00 Elena Gross's journey from chronic migraines to neuroscience ... 00:46 Distinguishing migraines from headaches ... 08:13 Energy deficit in the brain and ketones as a solution ... 15:05 Mechanisms and benefits of ketones for brain health ... 23:03 Micronutrients and mitochondrial support ... 28:20 Perfume, toxins, and migraine triggers ... 32:30 Hormonal, dietary, and oxidative stress factors in migraines ... 34:33 Exogenous ketones: Types, safety, and application ... 44:43 Brain Ritual supplement overview ... 47:04 Expanding beyond migraines: Mitochondria and neuropsychiatric health ... 57:31 Four pillars for mastering migraines ... 67:00 Actionable starting step for listeners ... 71:58 How to access Brain Ritual and community ... 73:10   Our Amazing Sponsors: Regenerive - Most cheap Ashwagandha is bulked up with stems and leaves to inflate the "actives." Those parts can bring compounds you don't actually want in your body. A root-only extract containing four newly identified bioactives, the ASHX4 Complex. Visit regenerive.co and use code NAT25 for 25% off.   StemRegen - A plant-based supplement protocol designed to enhance stem cell function. support your recovery, flexibility, and long-term vitality. Visit stemregen.co/NAT15 and use code: NAT15 for 15% off your order.   Blue Peptide Spray from Young Goose - brings the message back loud and clear. With NAD+ APEX to refuel energy, methylene blue to recharge your mitochondria, and GHK-Cu to tell your skin, "Hey, start making that collagen again!" It's longevity science, not cosmetic hype. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

We often think fitness is about pushing harder. More miles. More sweat. More effort.But what if the real secret to lifelong performance and metabolic health lies not in intensity, but in understanding the quiet signals your body sends every day?This week on Live Well Be Well, I'm joined by world renowned physiologist Dr. Iñigo San Millán, director of performance for UAE Team Emirates and one of the leading experts in mitochondrial health, endurance physiology, and chronic metabolic disease. Iñigo has spent decades studying elite athletes and everyday patients, and his work reveals a striking truth. The systems that help world champions thrive are the same systems that protect us from illness, fatigue, and burnout.We explore the science behind training zones, lactate, and metabolic flexibility, but also the human side of energy, longevity, and self trust. Because understanding your physiology is not only about performance. It is about reclaiming your capacity to feel strong, stable, and well in your own life.Here's What We Dive Into:- How mitochondria underpin long-term health and signal metabolic resilience.- Why Zone 2 training improves energy stability and protects against chronic disease.- What lactate truly reveals about your physiology beyond exercise performance.- How elite athletes teach us about metabolic dysfunction and adaptation.- Why nutrition shapes mitochondrial function and insulin sensitivity.- What drives burnout and fatigue at the cellular level and how to reverse it.- How to train smarter by listening to heart rate, breath, and internal cues.- Why most people are unintentionally overtraining or undertraining and how to find balance.Love,Sarah Ann

Send us a textMitochondrial fatty acid synthesis is a little-known but essential pathway that supports energy production and metabolic health.Summary: Dr. Sara Nowinski explains how mitochondria not only burn fuels to make ATP but also synthesize their own fatty acids inside the matrix; this conserved pathway produces lipoic acid (an essential enzyme cofactor) and longer-chain fats required for proper assembly of the electron transport chain, and disrupting it impairs respiration, glucose handling, and insulin sensitivity while enhancing it appears protective against obesity and heart injury.About the guest: Sara Nowinski, PhD is an assistant professor in the Department of Metabolism and Nutritional Programming at Van Andel Institute in Grand Rapids, Michigan, where since 2021 she has led a lab focused on mitochondrial biology and the mitochondrial fatty acid synthesis (mitoFAS) pathway.Topics Discussed:Basic mitochondrial energy production: food → pyruvate/fatty acids → acetyl-CoA → TCA cycle → electron transport chain → ATPMitochondrial fatty acid synthesis (mitoFAS): a bacterial-like pathway that builds fats on an acyl carrier protein inside the matrixLipoic acid: an 8-carbon fatty acid made only by mitoFAS, covalently attached to key enzymes (e.g., pyruvate dehydrogenase); cannot be rescued by supplements for cofactor useLonger mitoFAS products (14–16 carbons) stabilize electron transport chain assembly factors, explaining why pathway loss collapses respiration even when lipoic acid is intactKnocking out mitoFAS causes embryonic lethality, insulin resistance, poor glucose homeostasis, and a rare neurodegenerative disorder (MEPAN syndrome)Overexpressing the mitochondrial acyl carrier protein protects mice from diet-induced obesity, insulin resistance, and cardiac injuryMuscle cell differentiation fails without mitoFAS, hinting at a role in tissue development and repairPractical Takeaways:Supplemental lipoic acid can act as an antioxidant but cannot replace the lipoic acid your mitochondria must make themselves for enzyme function.Severe impairment of mitochondrial fatty acid synthesis is linked to insulin resistance and metabolic disruption, suggesting mitochondrial health (beyond just biogenesis) matters for glucose control.Lifestyle or future therapies that boost overall mitochondrial function (e.g., exercise via PGC-1α) may indirectly support tSupport the showAffiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. Special sale Nov 10 - Dec 1: Lumen is half off ($599 → $299), and MINDMATTER gets another 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, get $100 off for AquaTru Carafe, Classic and Under the Sink Units, and $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts

Today I discuss the significant impact of cooking oils, particularly industrial seed oils, on the obesity epidemic. We touch on the rise in linoleic acid consumption and its correlation with weight gain, inflammation, and other health issues. The speaker emphasizes the importance of understanding the effects of these oils and offers practical advice for healthier cooking alternatives.------------FREE Nutrition Cheatsheets:https://brian-getleaneatclean.beehiiv.com/subscribeClick to book a FREE 15 minute consult with Brian:https://calendly.com/bdgryn/15min------------Interested in Upgrading your Mitochondria, Improving Energy and Sleep! Check out Troscriptions: https://bit.ly/4ik5kK5Use Discount Code for 10% OFF: EATCLEAN----Watch Get Lean Eat Clean podcast video episodes on YouTube!YouTube.com/@briangryn3680-----How to Take Simple Steps to Reclaim the Body, Energy, and Strength You Had 10-15 Years Ago Using My Stepladder System:https://www.stepladdersystem.com/----B.rad Whey Protein Isolate Superfuel:The Best Protein on The Planet! Available in Two Delicious Flavors: Vanilla Bean and Cocoa BeanUse Coupon Code glec10off for 10% off your order!https://a.co/d/731gssV----My favorite health bars with clean ingredients!https://www.eatprima.com/BRIAN6816310% OFF with this link!

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The FDA belatedly liberates women's hormone replacement; Beta-blockers now deemed passé for routine heart attack aftercare; After most breast cancer surgery, adjuvant radiation brings no survival benefits; Can you drink caffeinated coffee if you have atrial fibrillation? Ignore frequent falls without attention to balance and stability training at your peril; Is it reasonable to contemplate a knee replacement surgery at 88? 

“Study” that's not even a study spreads panic about dubious melatonin-heart failure link; Should you ignore dr's advice to take powerful acid-blocking drugs? Novel implantable electrical pacemakers may bring relief to sufferers of severe constipation; Benefits of cocoa flavanols for heart, brain, athletic performance. Give the gift of healthy chocolate! Go to FlavaNaturals.com and use coupon code HOFFMAN20 for 20% off site-wide. Plus get free shipping on all orders over $30. 

If you're parenting an Autistic child and living in a state of constant alert (sensory overwhelm, dysregulation, sleepless nights, meltdowns, and the never-ending to-do list), this episode gives you a concrete biochemical map for how to get back to baseline. In today's conversation,I'm joined by Dr. Scott Sherr board certified internal medicine physician, certified practitioner of Health Optimization Medicine, and COO of Troscriptions, a company making physician formulated, precision-dosed buccal troches for focus, stress, sleep, and immune function. We talk about: What is the "sympathetic spiral of doom." What GABA deficiency actually looks like (and why calming down isn't as simple as "go meditate"). Why mitochondrial dysfunction and chronic inflammation show up so strongly in autistic and disabled kids and how supporting cellular energy can actualy reduce hyper-excitability. The real problem with giving kids 10–20 supplements at once. How targeted support can help caregivers feel better now, while they work the longer game of diet, lifestyle, and environment. Links Mentioned Dr. Scott Sherr's clinical practice: https://drscottsherr.com Troscriptions Products: https://troscriptions.com (Please work with a practitioner before using any product with a child.) If you found this episode helpful: Please share it with a caregiver who feels stuck in stress, burnout, or dysregulation. And grab my free guide: Gut Health Toolkit

On this episode of Vitality Radio, Jared dives deep into one of the most fascinating frontiers in functional nutrition—brain energy. He unpacks how ATP fuels your mind, why BDNF acts like “fertilizer for neurons,” and how lifestyle stressors, toxins, and poor sleep can dim your mental lightbulb. From there, he explores the natural tools that can reignite focus, memory, and long-term cognitive vitality. You'll hear how powerhouse nutrients can support mitochondrial performance, boost brain-derived neurotrophic factor, and promote sharper thinking—without the crash of caffeine or pharmaceuticals. Jared wraps up with three practical, results-driven protocols: one for focus and ADHD support, one for immediate memory and cognition, and one for long-term prevention of cognitive decline. Each stack can be customized to fit your individual goals so you can think clearer, focus longer, and age smarter—naturally.Brain Boosting Protocol CollectionShop the collection! Bundle and save - no code needed, just add to your cart to get:Buy 2 at 10% offBuy 3-4 at 15% offBuy 5+ at 25% offAdditional Information:Brain Boosting Protocol Blog Post#335: The Latest Research on Preventing and Reversing Dementia and Alzheimer's with Dr. Dale Bredesen#570: Liquid Yoga & Mind Fuel: Harnessing Mushrooms and Herbs for Focus and Calm#511: Unraveling NAD+ and NMN for Longevity and Anti-AgingVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

“You can't Type A your way into pregnancy. You can push, but your body will push back.” Hello Beautiful, Monica here supporting you to become the conscious mama you were born to be... This episode is packed with truth bombs, science-backed insights, and a big dose of real talk with fertility expert Kristen Karchmer. Together we peel back the layers of fertility burnout and talk about why women who “do everything right” are often the most exhausted, frustrated, and still not pregnant. Spoiler: it's not your age, it's your cellular energy. We dive into the reality that fertility clinics rarely talk about—how rushing into IVF or IUI without repairing the foundation of your health can actually set you back. Kristen shares how fatigue, stress, and even emotional disconnection play a far bigger role than the latest supplement on TikTok. It's about building resilience, coherence, and a sustainable rhythm that supports both your body and your future baby. And yes, we go there: the illusion of control, the obsession with apps and trackers, and the collective conditioning that tells women to “do more” instead of “be more present.” This episode is your permission slip to slow down, listen deeply, and start aligning your energy with your body's innate wisdom. Because fertility isn't a race, it's a frequency shift. “The only way to get a baby out is to surrender. The same goes for calling one in.” Timestamps 00:00 – Why your frequency matters more than your protocol 06:10 – Listening to your body instead of influencers 09:00 – The illusion of control and the myth of the fertility cliff 12:22 – How surrender prepares you for both conception and motherhood 18:12 – Generational burnout, epigenetics, and fertility 23:45 – Redefining success and rewriting the modern woman's blueprint “Surrender isn't giving up, it's getting out of your own way so your body can do what it was designed to do.” Full Transcript Over on the Blog: The Hidden Cost of Fertility Burnout (and Why Surrender Is Your New Superpower) with Kristen Karchmer https://www.findingfertility.co/blog/the-hidden-cost-of-fertility-burnout-and-why-surrender-is-your-new-superpower-with-kristen-karchmer Let's Do This Together

Fatigue isn't just about feeling tired, but also your body's warning signal that something much deeper is out of balance.  In this episode, I sit down with Dr. Evan Hirsch, founder of the Energy MD Method, to uncover his proven four-step process for restoring energy, reversing long COVID, and resolving chronic fatigue for good. We discuss the Toxic Five: the underlying root causes that drain your vitality and how you can retrain your nervous system, open detox pathways, and naturally restore your mitochondria. Dr. Hirsch shares his personal five-year battle with exhaustion, what finally worked, and how thousands have reclaimed their energy using the same framework.    "Our bodies are always working for our best interest. You can't just replace mitochondria 'to high heaven' and expect results. You have to fix the underlying problem that's forcing them to shut down." ~ Dr. Evan Hirsch   In This Episode: - Dr. Evan's journey through chronic fatigue - An overview of long COVID and the propagation of spike proteins  - Long COVID vs chronic fatigue - Why some people get long COVID and others don't - The 4-step process to resolve chronic fatigue and long COVID - Success stories and the program timeline - Addressing sleep issues and promoting sleep optimization - Mitochondria damage and cell danger response - Stats on chronic fatigue syndrome - Challenges and shortcomings in medical testing   Products & Resources Mentioned: Bon Charge Red Light Face Mask: Just go to https://boncharge.com/myersdetox and your discount will be automatically applied at checkout! Tru Energy Lip Peptide Treatment: Visit https://trytruenergy.com/wendy3 now to claim your special Buy One, Get One Free offer for a limited time. Organifi Happy Drops: Get 20% off at https://organifi.com/myersdetox with code MYERSDETOX. Chef's Foundry P600 Cookware: Get an exclusive discount just for my listeners by going to https://bit.ly/myersdetox    Energy MD Method Program: Learn more and apply at https://www.energymdmethod.com/  Heavy Metals Quiz: Take the free quiz and get a custom detox video guide at https://heavymetalsquiz.com.   About Dr. Evan Hirsch: Dr. Evan Hirsch (MD), known as the Energy MD, is a world-renowned fatigue expert, bestselling author, and professional speaker. After his own years-long struggle with chronic fatigue, he developed the Energy MD Method, a science-based four-step process to identify and remove the root causes of exhaustion, long COVID, and mitochondrial dysfunction. Through his global online program, he's helped thousands reclaim their vitality naturally. Learn more at https://www.energymdmethod.com/  and on Instagram https://www.instagram.com/evanhirschmd/    Disclaimer The Myers Detox Podcast was created and hosted by Dr. Wendy Myers. This podcast is for information purposes only. Statements and views expressed on this podcast are not medical advice. This podcast, including Wendy Myers and the producers, disclaims responsibility for any possible adverse effects from using the information contained herein. The opinions of guests are their own, and this podcast does not endorse or accept responsibility for statements made by guests. This podcast does not make any representations or warranties about guests' qualifications or credibility. Individuals on this podcast may have a direct or indirect financial interest in products or services referred to herein. If you think you have a medical problem, consult a licensed physician.

Brand New episode! What if the missing link in your recovery isn't another supplement or stretch, but energy at the cellular level? We sit down with Dr. Zulia Frost—medical doctor, researcher, and co-founder of Recharge Health—to unpack how photobiomodulation, neuromodulation, and sound can help your body heal faster, perform better, and sleep deeper without side effects.Zulia's story is a powerful one: a devastating car accident, spinal fractures, and paralysis in her right leg. Conventional care saved her life, but it was targeted red and infrared light, gentle nerve stimulation, and a disciplined movement routine that rebuilt it. She explains in plain language how red and near-infrared wavelengths interact with mitochondria to increase ATP, release nitric oxide, and open blood flow—key steps that reduce pain, accelerate collagen repair, and restore function in joints and muscles. We compare sunlight to devices, discuss why consistent dosing matters, and reveal why wearable, skin-contact designs can deliver a reliable, high-intensity dose where you need it most.Get 10% off on FlexBeam at www.ChampionsMojo.com/FlexBeam and enter championsmojo as a coupon code at check out. Pain lives in the nervous system as much as in tissue, so we dive into neuromodulation for endorphin-driven relief and layer in sound therapy to shift brain waves toward calm. Zulia shares practical routines for athletes and everyday movers: short sessions for acute injuries, broader mapping for chronic issues, and pre-activation before training to boost output. She also offers simple, science-backed habits—consistent bedtimes, a few minutes of morning red light over the chest or abdomen, stretching before the day's load, and brief walks—that support circadian rhythm, gut health, and resilience over time. We close with clear guidance on facial use, eye safety, and how to personalize settings without guesswork.Whether you're rehabbing a shoulder, chasing a PR in the pool, or trying to sleep through the night, this conversation gives you a practical blueprint to turn light, sound, and routine into results. If this helped you rethink recovery, follow the show, share it with a friend, and leave a quick review to help others find it.• photobiomodulation basics and why mitochondria matter• nitric oxide, blood flow, and faster tissue repair• wearable versus panel devices and sunlight trade-offs• dosing for acute injuries, chronic pain, and sport prep• neuromodulation for pain relief and endorphins• sound therapy, brain waves, and deeper sleep• routines for circadian health, stretching, and breathing• gut microbiome support with red light• safe face use and eye protection guidance• a proactive approach to long-term vitalityVisit Recharge Health to learn more about FlexBeam and create your routine todayEmail us at HELLO@ChampionsMojo.com. Opinions discussed are not medical advice, please seek a medical professional for your own health concerns. Check out Kelly's Books at www.KellyPalace.com

I have hypothyroidism.  Do I need to be concerned about low ferritin levels?What are the benefits of lower-dose fish oil?Is there a connection between melatonin supplementation and depression?Can I take melatonin while on warfarin?What to do about the state of our healthcare system?

Are children's IQs going down?An overview of medical reversalsCan you comment on the melatonin and heart failure study?Result of a prostate artery embolization

Episode 4 — Starlight Inside, The Mitochondria EpisodeShow Notes / DescriptionIn today's episode, we zoom inward—into the living universe inside your cells—to explore how your mitochondria (your body's tiny suns) create the energy that fuels everything you do… and what happens when life burns too hot for too long.We talk about the ancient origins of your mitochondria, why their DNA is passed almost entirely through your maternal line, and how your mother's light and your father's genetic architecture work together to shape your vitality, resilience, and metabolism.Then we step into the “forest canopy” around your mitochondria—your antioxidant and repair systems—including superoxide dismutase, catalase, glutathione, and the master regulator NRF2.You'll learn:✨ Why stress, infections, chronic busyness, poor sleep, toxins, and nutritional deficiencies can overwhelm your antioxidant canopy✨ How your body actually protects you by dimming energy (instead of failing)✨ Why some people rebound quickly and others crash harder✨ And how daily nourishment rebuilds your internal ecosystemWe also meet “Anna,” a high-performing woman who didn't realize her exhaustion was a sign of her body protecting her—not betraying her.Her story will help you understand why energy depletion often isn't about willpower, but about biology.Finally, I'll share a deeply personal story from my herbal medicine training—a free clinic, a big pot of kitchari, and the moment I learned how profoundly simple nourishment can shift the nervous system.This episode is for you if:

Ready to boost your energy and future-proof your health? In this episode, I'm joined by expert neuroscientist Dr. Siobhan Mitchell, who breaks down why your mitochondria—the tiny powerhouses inside your cells—are the secret to healthy aging.  She explains how the perimenopause and menopause transition is not just hormonal, but a neuroendocrine shift that impacts your brain, mood, energy, AND vitality.  And even if you're doing your best to bring on lifestyle recommendations for optimizing mitochondrial health, odds are you still need more support than just that in midlife. So, that's where the supplement MitoQ comes into play.  As MitoQ's Chief Scientific Officer, Dr. Mitchell reveals how this advanced antioxidant works deep inside your cells to enhance mitochondrial function, boosting mental clarity and long-term longevity.  Tune in and discover how to fuel your energy, elevate your mood, and embrace midlife feeling stronger than ever! Dr. Siobhan Mitchell  Siobhan Mitchell is the chief scientific officer of MitoQ. She completed her PhD at SUNY Albany and a post-doctoral fellowship on brain aging at the University of Washington. Siobhan has held roles at the three largest food companies in the world (Unilever, Nestle, and Pepsico), leading trials worldwide, which researched the effects of nutrition on cognitive decline, mood, and performance. She was also senior director at Noom, where she directed a team investigating chronic disease management, weight loss, and mental health digital programs using cognitive behavior therapy methods. IN THIS EPISODE Why mitochondria are a key contributing factor to aging  Preventing menopause symptoms in relation to brain changes  Research on estrogen levels in menopause for longevity  Lifestyle changes for enhanced cognitive functioning  The impact stress has on your mitochondrial function  How to notice if your mitochondria aren't working well  How MitoQ supplementation boosts cell vitality and longevity  Ways to measure your mitochondrial function  QUOTES“You get these overactive mitochondria that are also producing energy and oxidative stress at much higher levels, and these oxidative stress mechanisms can also bring on faster aging through inflammation and things like that.” “[MitoQ] is basically helping protect your mitochondria from excessive oxidative stress. It gets into the mitochondria better than any other supplement on the market because it was especially engineered to have this tag that allows it to get into the mitochondria up to [about] 90%.” RESOURCES MENTIONED Order my new book: The Perimenopause Revolution https://drmariza.com/book Use code DRMARIZA and get 15% off your order of Silverbiotics https://silverbiotics.com/discount/drmariza Use code: ENERGIZED for 10% off your order of MitoQ HERE! http://mitoq.com MitoQ on Instagram Siobhan on X  RELATED EPISODES  #688: Unlock Cellular Energy and Longevity with Urolithin A + Mitochondrial Optimization with  Jen Scheinman  #653: Mitochondria, Menopause & Metabolism: The Cellular Secret to More Energy After 40 with Dr. Felice Gersh #663: From Wired and Tired to Calm and Energized: The GABA-Mitochondria Connection + How to Fix It at the Cellular Level with Dr. Scott Sherr #623: Red Light Therapy for Upgrading Your Mitochondria, Cellular Energy, Skin and Brain Health with Jonathan Otto #690: The Perimenopause Revolution: Why midlife isn't the end — it's the beginning of your most energized, powerful, and vibrant self

This episode is brought to you by Troscriptions. Tired, drained, and ready for a change? You are not alone. In fact, 94% of Americans experience some degree of mitochondrial dysfunction that is possibly leading to unwanted symptoms such as brain fog, fatigue, weight gain, and even poor mental health. In this episode with Dr. Scott Sherr, MD you will learn how modern life has made us evolutionarily unfit for our environment, and why living in constant fight-or-flight mode leads to what he calls "the sympathetic spiral of doom." Together, we explore early warning signs of cellular decline, the link between mood and mitochondria, and practical strategies for restoring balance — from better sleep and parasympathetic recovery to optimizing nutrition and lab testing. This episode is a masterclass in understanding your body's energy systems and how to reclaim your vitality at the cellular level. Follow Scott @drscottsherr Follow Chase @chase_chewning ----- 00:01 What Is Mitochondrial Dysfunction? — 94% of U.S. adults struggle with energy and detoxification. 01:28 Meet Dr. Scott Sherr — His background in internal medicine and health optimization. 04:00 The Science of ATP — How your body creates 150 pounds of energy every day — and the hidden cost. 06:58 What's Breaking Our Mitochondria — Sugar, medications, toxins, and chronic stress. 09:28 Why We're Not Built for Modern Life — Evolutionary mismatch and constant overstimulation. 12:52 Energy Production vs. Detoxification — The "plumbing" analogy that explains cellular backup. 15:48 Early Warning Signs — Fatigue, mood swings, slow recovery, and why energy equals emotion. 20:59 You Can Feel Fine and Still Be Unhealthy — Why "not sick" doesn't mean "optimized." 24:53 Optimizing Cellular Health — Nutrient testing, heavy metals, inflammation, and resilience between ages 21–30. 27:54 The #1 Mitochondrial Killer: Stress — Why sympathetic overdrive is the hidden threat to energy. 30:41 The Sympathetic Spiral of Doom — How stress hormones shut down energy production. 35:59 Breaking the Spiral — Awareness, HRV, recovery, and restoring nervous system balance. 41:46 The Role of Safety and GABA — How feeling unsafe keeps you stuck in fight-or-flight. 46:49 Biohacks That Actually Work — GABA, sauna, sleep, and Dr. Sherr's nightly recovery ritual. 49:31 Modeling Health for the Next Generation — Mindfulness, meditation, and leading by example. 53:15 Ever Forward — Energy as currency and the art of being both present and progressing. ----- Episode resources: Take the energy quiz and see how Troscriptions can help you take your life back. Use code EVERFORWARD at checout. Watch and subscribe on YouTube

Just 4 simple lifestyle measures deliver 9 additional years of disease-free healthspan; Study underscores protein's role in staving off cancer, heart disease, and death; CoQ10 scores vs. neurodegeneration; Urolithin A (Mitopure®️) found to support athletic performance, immune function; Why you should ignore some influencers' advice to avoid fish oil. 

As little as 3000 steps per day can slow progression to Alzheimer's Disease; Self-reports of memory impairment soaring among young people; New study vindicates unprocessed red meat—and even often-vilified processed red meat—for cancer and overall health. Prostate artery embolization (PAE) offers new non-invasive option for men's age-related urinary problems; Targeting the mitochondria and the microbiome for Parkinson's Disease; Popular prostate and hair loss prevention drugs linked to depression and suicide—while Cialis for urinary symptoms may stave off cardiovascular disease; Discovery that a safe, cheap medication may increase survival after breast cancer surgery. 

In this science-backed and empowering episode of Resiliency Radio, Dr. Jill Carnahan is joined by Dr. Siobhan Mitchell, Chief Scientific Officer of MitoQ, to explore how optimizing mitochondrial health can revolutionize the way we age, perform, and heal. ⚡ Together, they unpack the critical role mitochondria play in everything from immune function and brain health to energy production, resilience, and mental well-being. Discover how MitoQ, a breakthrough antioxidant supplement, supports mitochondrial function, enhances athletic performance, and may even aid mental health and PTSD recovery by repairing cellular damage and reducing inflammation.

Pain isn't just in your body, it's in your brain. In this groundbreaking episode, Host Dave Asprey sits down with Dr. Daniel Amen to reveal how emotional and physical pain share the same neural circuits and how you can rewire them for relief, resilience, and longevity. You'll learn practical tools to break the “doom loop” of pain, restore neuroplasticity, and retrain your brain for calm, healing, and high performance. This is essentiallistening for anyone ready to stop managing pain and start hacking it. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR The Washington Post called Dr. Daniel Amen the most popular psychiatrist in America. He is a former infantry medic and board certified child and adult psychiatrist who trained at the Walter Reed Army Medical Center in Washington, DC. He is the CEO and founder of Amen Clinics, with 11 locations nationwide and home to the world's largest brain imaging database for psychiatry with nearly 300,000 SPECT scans on patients from 155 countries. Dr. Amen is a 12 time New York Times bestselling author, including the books Change Your Brain, Change Your Life, Healing ADD, Memory Rescue, Raising Mentally Strong Kids, and The End of Mental Illness. He has published over 90 scientific articles and led groundbreaking brain imaging research on NFL players, childhood trauma, negativity bias, reversing brain aging, obesity and the brain, and predicting treatment responses. With over 10 million followers and multiple PBS specials, his mission is bold: to end mental illness by creating a revolution in brain health. His newest book Change Your Brain, Change Your Pain explores the neuroscience of pain and how to heal it through brain optimization and functional medicine. Host Dave Asprey and Dr. Amen uncover how suppressed emotions, inflammation, gut health, and mitochondrial function all influence pain and what you can do to reverse it using biohacking, functional medicine, and supplements. They explore how chronic pain rewires neural pathways, how to activate your brain's natural calming switch, and why techniques like hypnosis, red light therapy, rage journaling, and havening can restore balance to your nervous system. You'll also learn the surprising links between aspartame, Tylenol, and generational anxiety, and how to protect your mitochondria to optimize energy, metabolism, and emotional resilience. This episode delivers practical, science based tools for brain optimization, sleep optimization, neuroplasticity, and anti aging while connecting the dots between biohacking, psychology, and functional medicine to help you live smarter not harder. You'll Learn: • How emotional pain and physical pain run on the same brain circuits • Why suppressed rage can trigger chronic pain and how to release it • The link between inflammation, gut health, and brain suffering pathways • How supplements like saffron, curcumin, and omega 3s support pain relief and mood • Why red light therapy, hypnosis, and havening boost neuroplasticity and calm the nervous system • How environmental toxins, aspartame, and Tylenol disrupt mitochondria and increase pain • Simple daily habits to retrain your brain for resilience, optimism, and longevity Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: chronic pain neuroscience, emotional pain circuits, Change Your Brain Change Your Pain, Dr. Daniel Amen, Dave Asprey, biohacking, neuroinflammation, anterior cingulate cortex, SPECT imaging, mitochondrial metabolism, functional psychiatry, neuroplasticity, rage therapy, havening technique, red light therapy, saffron supplements, aspartame toxicity, gut brain axis, trauma healing, pain hacking BrainMD Happy Saffron Plus: Affiliate Link: https://www.awin1.com/cread.php?awinmid=89351&awinaffid=855302&ued=https%3A%2F%2Fbrainmd.co…Dave's 15% OFF Discount Code: DAVE15Please note – works on one-time purchases or the first order of a subscription.Thank you to our sponsors! • AquaTru | Go to https://aquatruwater.com/daveasprey and save $100 on all AquaTru water purifiers. • NeuroVeda Health | Go to https://www.neurovedahealth.com/aspery to learn more and book your week. • BON CHARGE | Go to https://boncharge.com and use code DAVE for 15% off. • ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Dave's Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated• Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 — Trailer 01:25 — Dr. Amen's Brain Scan Research 02:11 — Physical vs Emotional Pain 05:15 — Childhood Trauma and Pain 08:10 — The Doom Loop Explained 14:01 — Havening Technique 18:27 — Training Positivity and Hope 22:11 — Rage Therapy and Journaling 26:44 — COVID and Brain Inflammation 29:41 — Mitochondria and Energy 36:14 — Pain Relief Protocol 39:32 — Saffron for Pain 43:28 — Aspartame and Anxiety 47:30 — Pain Switches in the Brain 50:50 — Red Light Therapy 52:39 — Fear and Pain Loops 56:36 — Environmental Toxins58:21 — Final ThoughtsSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

I used to assume conception began at the first sign of pregnancy — until I learned about Trimester Zero. The 100-day window before conception may be the most powerful period in shaping your baby's lifelong health — and your own. In this minisode, I sit down with Vida Delrahim and Ronit Menashe, co-founders of WeNatal, to unpack what science now calls the pre-pregnancy trimester. We talk about how both women and men can dramatically influence fertility and genetics before conception through nutrition, lifestyle, and the health of one mighty organelle — the mitochondria.This episode features highlights from our full conversation, which premiered August 12th, 2025. Watch the full episode here → https://www.youtube.com/watch?v=5gztCFH603g About the guests:After experiencing miscarriages just a week apart, best friends Vida and Ronit were devastated — and confused. Both were healthy, both on prenatal vitamins, and yet doctors dismissed their losses as “random” or “age-related.” They partnered with leading experts, pored over research, and created a science-backed prenatal system for both women and men. What began as a personal mission has grown into WeNatal — a movement giving couples the knowledge, tools, and products to support conception, pregnancy, and the lifelong health of future generations. *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsor for supporting this episode. Check them out and enjoy exclusive discounts: HoneyloveSave 20% Off Honeylove at https://www.honeylove.com/NEURO. *** I'm Louisa Nicola — clinical neurophysiologist — Alzheimer's prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer's risk — and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ *** Topics discussed: 00:04 – What Is Trimester Zero?00:57 – Nutrient Reserves and Baby Brain Development01:31 – Why Early Nutrition Matters (and Morning Sickness Reality)02:03 – Male Fertility: Sperm Quality and DNA Health02:27 – The Power of Epigenetics: Passing Down More Than Genes03:39 – The Three Pillars: Choline, Sperm, Epigenetics04:00 – Nutrition and Mitochondrial Health in Eggs05:37 – Mitochondria, Aging, and Fertility Myths06:09 – Why Egg Quality Matters More Than Quantity07:05 – Miscarriage Myths and Male Factor Fertility08:05 – How Modern Life Impacts Reproductive Health09:32 – Why Supplements Like CoQ10 and PQQ Matter Learn more about your ad choices. Visit megaphone.fm/adchoices

Send us a textSummary: I unpack why medicine sometimes reverses course—and how you can tell sound evidence from shiny anecdotes—with physician-author Dr. Adam Cifu of the University of Chicago and co-author of Ending Medical Reversal.Key topics & takeawaysWhy medicine “flips”: Plausible theories + observational data → premature guidelines; true answers require randomized trials. Classic examples: menopausal hormone therapy, early peanut avoidance, and stents for stable angina (LEAP trial, COURAGEOpen-minded skepticism: Ask, “What's the human outcomes evidence?” Cool mechanisms and moving testimonials aren't proof.Hype outside the clinic: Mitochondria “rechargers,” microbiome panaceas, and biological age tests are intriguing—but not ready for prime time.Nutrition sanity:  For supplement evidence summaries, I like Examine.When AI helps (and when it doesn't): Tools can orient you to established topics; they're weaker on breaking studies. Look for linked primary sources.N-of-1 experiments: When evidence is uncertain and the outcome is measurable (sleep, blood pressure, pain), test on yourself—track a baseline, try the change, measure again, and, if possible, stop-start to confirm. Use symptom diaries, validated scales, or wearables.Humility is a signal: Trust sources that sometimes conclude “we don't know.” I often check Cochrane Reviews for balanced syntheses.About my guest Adam Cifu, MD is a professor of medicine at the University of Chicago, author of 140+ peer-reviewed papers, and co-author of Ending Medical Reversal. He writes at Sensible Medicine.Call to action If this episode helped you think more clearly about health claims, share it with a friend and leave a quick review on Apple or Spotify. For my newsletter on practical, evidence-supported longevity, visit DrBobbyLiveLongAndWell.com.

Ready to transform your health, beat the fatigue, and defy aging? This is the episode you need!Elisabeth Carson sits down with Dr. Catherine Arnston, CEO of EnergyBits and the leading expert, "voice of algae" to dive deep into the science behind microalgae, the most nutrient-dense food in the world. You'll learn the shocking truth about this ancient superfood that's endorsed by NASA and the United Nations.What You'll Discover:The Mitochondria Connection: Learn how microalgae, especially spirulina, delivers Superoxide Dismutase (SOD), the critical enzyme that repairs and protects your mitochondria—the power source of your cells.Stop the Decline: Understand why your body's natural production of protective enzymes (like SOD) drops after age 30/40, leading to fatigue, hormonal issues, and chronic disease.Energy vs. Detox: Discover the key differences between Spirulina (Energy Bits), which acts as a nourishing, instant fuel, and Chlorella (Recovery Bits), Mother Nature's ultimate detox crew for removing heavy metals, glyphosate, and mold toxins.Anti-Aging & Hormones: Find out how restoring cellular energy and balancing your nutritional foundation is the key to improving skin health, hormonal balance (especially through perimenopause/menopause), and feeling truly complete.A Food, Not a Supplement: Why algae is regulated as a whole food and is more nutrient-dense than an entire plate of vegetables, making it the easiest way to fill nutritional gaps without gas or cooking.Dr. Arnston shares her mission and personal story of launching EnergyBits after her sister's cancer diagnosis, realizing that true healing starts with maximizing the body's natural defenses through nutrition.

#180 - New Mitochondria Research: The Untold Anti-Aging Hack You Need to Know You've heard of mitochondria — the “powerhouses of the cell,” right? But here's what most people don't know: those tiny energy factories are also the secret behind how your skin ages. In this episode, we're taking a deep dive beneath the surface (literally) to uncover how your skin's mitochondria control everything from collagen production and elasticity to wrinkle formation and inflammation — and what you can do to keep them healthy, energized, and glowing. We'll unpack how UV exposure, stress, poor sleep, and even skincare products can damage mitochondrial DNA… and why that matters for your skin's vitality and your long-term health. And yes — we'll also talk about two game-changing molecules that actually work: CoQ10 and melatonin. These two are your mitochondria's dream team, boosting energy, repairing damage, and keeping your skin youthful at the cellular level. You'll learn: ⚡️ How your mitochondria literally fuel your skin's glow (and what happens when they burn out)

In this episode of the Ageless Future Podcast, Cade Archibald explores how white adipose tissue (white fat) can be transformed into metabolically active brown fat to improve energy, fat loss, and overall health. He explains how excess white fat impairs mitochondrial function and nitric oxide production—two keys to aging and vitality. Cade discusses practical strategies like cold exposure, high-intensity interval training (HIIT), and mitochondrial-boosting peptides (including MOTS-c, Epitalon, and Adipotide). He also reviews a fascinating animal study showing Adipotide reduced abdominal fat by 27% and improved insulin sensitivity by 50% in just 28 days. Listeners are challenged to try cold showers, HIIT, and energy tracking for better metabolic function and cellular health.www.agelessfuture.comLIKE/FOLLOW/SUBSCRIBE:YouTube -https://www.youtube.com/@ReganArchibald / https://www.youtube.com/@Ageless.FutureInstagram: https://www.instagram.com/ageless.future/Facebook: https://www.facebook.com/AgelessFutureHealth/

Mentor Sessions Ep. 037: Michael Morelli on Rock Bottom Addiction Recovery, Building a Bitcoin-Powered Fitness Empire, Parallels to Sound Money & Radical LongevityMichael Morelli's Bitcoin journey mirrors his brutal addiction recovery: from high more than sober for a decade, snorting oxycodone amid bankruptcy and affairs, to a 113-day shred from 25% to 8% body fat—bootstrapping FitScript into a multimillion-dollar data-driven health empire coaching 600+ men with peak biomarkers while stacking BTC as a maxi since 2020. Inspired by Saifedean Ammous' "The Bitcoin Standard," Morelli draws logical parallels between paleo nutrition's ancestral simplicity and Bitcoin's finite, sound money—why it's the only asset that "just seems logical" in a fiat-fueled health and wealth disparity crisis. In this BTC Sessions interview, he busts carnivore myths (labs "fucking wrecked"), unpacks peptides for faster gains, red light therapy hacks, and his no-excuses mantra: if a coke-addicted bankrupt can rebuild to live until 150, stacking sats with low-time preference, Bitcoiners have zero excuses for subpar health. Topics:Brutal rock bottom: Addiction, abuse & what led there113-day rebirth: Fatherhood spark & no-excuses mindsetBootstrapping empire: Mom's basement to millionsFitness myths busted: Carnivore dangers & paleo logicBitcoin awakening: Shitcoins to maxi via SaifedeanHealth-money parallels: Disparity extremes & white coat trapsActionable optimization: Low-hanging fruit for BTC stackersPeptides decoded: Mechanisms for faster recoveryRed light therapy: Mitochondria boost & hair regrowthEntrepreneurship grit: Fuck Aging brand & mindset masteryChapters:00:00 Teaser & Intro01:24 Background & Journey02:09 Addiction & Rock Bottom04:42 No Excuses06:10 Abuse & Roots13:04 Fitness & Control16:34 Empire Collapse19:03 Biz Success23:42 Myths & Paleo26:13 Lab & FitScript31:05 BTC Parallels & Journey33:06 Disparities & Pharma38:50 Actionable Tips43:07 Longevity & Alpha47:53 Peptides & Red Light1:02:45 Outro & DiscountAbout Michael MorelliPerformance health engineer, founder FitScript. Test, don't guess. X.com: @morellifitFitScript: fitscript.me (mention podcast for $1000 off)Check previous ep with Prince Filip of Serbia: https://youtu.be/h7kyNNUuLOg

Daylight Savings Time changeover health myths busted; A doctor breaks her ankle and is billed $64,000 in uncovered expenses; Vitamin D shields life-prolonging telomeres, may help depression; The vaunted DASH Diet for hypertension faces off against low-carb alternative; The critical first 1000 days after conception—early life sugar avoidance yields major later life health dividends; Do you really need hot water to disinfect your hands?

Send us a textHow mitochondria travel between cells and how this hidden communication shapes metabolism, immunity, and even potential therapies.Episode Summary: Dr. Jon Brestoff talks about mitochondrial dynamics inside cells, their transfer between unrelated cells (distinct from inheritance during division), and its roles in adipose tissue communication, macrophage cleanup, and systemic metabolic signaling; they explore how high-fat diets disrupt this process, potential hormetic benefits, therapeutic mitochondria transplantation for diseases like Leigh syndrome and obesity, and broader immunometabolism crosstalk.About the guest: Jon Brestoff, MD, PhD is an associate professor of pathology and immunology at Washington University School of Medicine in St. Louis, where he directs the Initiative for Immunometabolism.Discussion Points:Mitochondria per cell range from ~100-5000; they move via fusion/fission, vertical inheritance (cell division), or horizontal transfer without division.Transfer mechanisms: free release, extracellular vesicles, or tunneling nanotubes using cytoskeleton transport.In healthy fat tissue, adipocytes routinely donate mitochondria to macrophages for degradation (quality control); high-fat (lard-based, long-chain FA) diets block macrophage uptake, diverting mitochondria to other organs.Diverted mitochondria may induce “mito-hormesis” (mild oxidative stress boosting antioxidants) or signal adipocyte metabolic status inter-organ.Mitochondria transplantation shows promise in animal models for ischemia-reperfusion, obesity, and mitochondrial diseases.Immune cells prefer glycolysis but have low mitochondrial biomass; transplanted mitochondria tilt T-cells toward anti-inflammatory regulatory phenotype.Circulating cell-free mitochondria rival immune cell numbers.Obesity inflammation stems from dying oversized adipocytes releasing lipids/mitochondria, forming crown-like structures with pro-inflammatory macrophages.Leigh syndrome from genetic mutations disrupting the electron transport chain.Transfer may be an evolutionary relic of endosymbiosis; cells may selectively use exogenous mitochondria like a “generator” during metabolic crisis.Reference Paper:Study: The power and potential of mitochondria transferRelated Episode:M&M 260: Energy Resistance Principle in Life, Healing & Disease | Martin Picard & Nirosha MuruganSupport the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

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In this episode of the Smarter Not Harder Podcast, Dr. Latt Mansor joins Jodi Duval for a deep-dive into ketones, mitochondria, and metabolic flexibility — the science of how your body creates, manages, and optimizes energy. From brain performance to heart health, this conversation bridges Oxford-level physiology, real-world biohacking, and the future of metabolic medicine. Join us as we explore: How ketones work as both fuel and signaling molecules to power your brain, muscles, and heart Why metabolic flexibility is the key to longevity, resilience, and cognitive clarity The difference between endogenous and exogenous ketones — and how to use Ketone IQ effectively The link between mitochondrial health, NAD⁺, and energy metabolism Groundbreaking research on ketones in Alzheimer's, mental health, and heart-failure recovery This episode is for you if: You want to understand how ketones can boost cognition, focus, and energy You're a clinician, athlete, or optimizer seeking to personalize supplementation and performance You're curious about the future of metabolic psychiatry and mitochondrial medicine You want smarter, not harder, ways to enhance metabolism, longevity, and recovery You can also find this episode on...YouTube: https://youtu.be/ictAuB43lIs Find more from Dr. Latt Mansor:Website: https://ketone.com Instagram: https://instagram.com/lattmansor/ LinkedIn: https://linkedin.com/in/lattmansor Find more from Smarter Not Harder:Website: Smarter Not Harder Podcast Instagram: https://instagram.com/troscriptions Get 10% Off your Clinical Metabolomics Module at HOMeHOPe using code POD10 → https://homehope.org/products/clinical-metabolomics Get 10% Off your Troscriptions order with code PODCAST10 → https://troscriptions.com Get daily metabolic-health content and future-of-medicine insights by following @troscriptions on Instagram.

Dr. Hoffman continues his conversation with  Dr. Nathan Bryan, a pioneering scientist, health innovator, biotech entrepreneur, and author of "The Secret of Nitric Oxide: Bringing the Science to Life." 

In this episode of the Intelligent Medicine podcast, Dr. Ronald Hoffman discusses the vital role of nitric oxide in human health with expert Dr. Nathan Bryan, a pioneering scientist, health innovator, and biotech entrepreneur who's reshaping the conversation around longevity, human performance, and the truth behind modern health. He's author of "The Secret of Nitric Oxide: Bringing the Science to Life." They explore the science behind nitric oxide, its numerous benefits, including its impact on cardiovascular health and erectile function, and the misconceptions surrounding common supplementation methods. Dr. Bryan explains how his research led to the development of effective nitric oxide supplements and a nitric oxide-friendly lifestyle. They also address the safety and efficacy of combining nitric oxide support with erectile dysfunction medications, and Dr. Bryan shares insights into ongoing research and future innovations in the field.

This week I interviewed Katie Hardie! Katie is a Board-Certified Holistic Nutritionist and FDN Practitioner who helps high performers reclaim their energy, optimize nutrition, and achieve lasting results through bio individual, science-driven programs. We discussed how most of your health gains will be done in the kitchen along with:- what to buy when going to the grocery store- the importance of functional medicine- Katie's favorite tests for optimal healthand her one tip to get your body back to what it once was!Connect with Katie:Website: https://www.mypeak365.com/ Instagram: https://www.instagram.com/mypeak365/ Links:Interested in Upgrading your Mitochondria, Improving Energy and Sleep! Check out Troscriptions: https://bit.ly/4ik5kK5Use Discount Code for 10% OFF: EATCLEAN----Watch Get Lean Eat Clean podcast video episodes on YouTube!YouTube.com/@briangryn3680-----How to Take Simple Steps to Reclaim the Body, Energy, and Strength You Had 10-15 Years Ago Using My Stepladder System:https://www.stepladdersystem.com/----B.rad Whey Protein Isolate Superfuel:The Best Protein on The Planet! Available in Two Delicious Flavors: Vanilla Bean and Cocoa BeanUse Coupon Code glec10off for 10% off your order!Amazon (case sensitive): GLEC10OFFB.rad Nutrition.com: glec10offhttps://a.co/d/731gssV----My favorite health bars with clean ingredients!https://www.eatprima.com/BRIAN6816310% OFF with this link!----| Listen to the Get Lean Eat Clean Podcast |►Apple Podcasts | https://podcasts.apple.com/us/podcast/get-lean-eat-clean/id1540391210►Spotify | https://open.spotify.com/show/0QmJzYZsdV6tUNbDxaPJjS| Connect with Brian |►Website | https://www.briangryn.com►Instagram | https://www.instagram.com/bdgryn►Facebook | https://www.facebook.com/getleanandeatclean►Twitter | https://twitter.com/grynnerwinner

Welcome to the Mind Muscle Connection Podcast!In this episode, I sit down with Dr. Phil Batterson to talk about VO2 Max for Lifters: The Untapped Lever for Performance, Fat Loss & Longevity.We cover why it matters for performance, how it connects to recovery and fat loss, and simple ways to improve it without wrecking your lifting progress. If you're serious about building muscle or your fitness journey, this episode is a must listen!Let's talk about:00:47 Introduction to Dr. Phil Batterson04:22 Mitochondria & why it matters06:00 Endurance and Cardio10:51 Cardio vs Muscle Gains30:21 Dr. Phil's training38:40 VO2 Max01:06:23 How VO2 max impacts lifters01:09:10 Misconceptions01:11:16 Where to find Dr. PhilFollow Dr. Phil Batterson on Instagram:https://www.instagram.com/drphilbatterson/Follow me on Instagram for more information and education:  jeffhoehn_FREE 30 Min Strategy Call: HEREBody Recomp Masterclass: HERENutrition Periodization Masterclass: HEREHow You Can Work With Me?: HERECoaching application: HEREBody Recomp Checklist 2.0: https://chipper-producer-6244.kit.com/26b5c9f94a

Discover how decoding your DNA can unlock the full potential of plant medicine. This episode delivers a cannabis masterclass for biohackers, revealing how personalized genetics are transforming human performance, brain optimization, and longevity. You'll learn how to identify your ideal cannabis and supplement protocols, balance your endocannabinoid system, and turn precision data into powerful healing. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Len May, MSc, visionary authority in personalized medicine and CEO of EndoDNA, the world leader in DNA-based wellness technology. With over 25 years of pioneering work in genomics, epigenetics, and medicinal cannabis, Len's patented DNA decoding system maps your unique genotypes to design tailor-made health solutions. His company holds the world's largest real-world efficacy database in precision wellness, integrating functional medicine, AI-driven analytics, and genetic data to create personalized blueprints for optimal brain function and performance. Together, Dave and Len explore how your genetic code determines how you respond to cannabis, psychedelics, nootropics, and supplements—and how to use that data to reduce anxiety, improve sleep optimization, and enhance focus. You'll learn how decoding your DNA can guide anti-aging strategies, mitochondrial performance, metabolism, and neuroplasticity, revealing new ways to live longer and smarter. This episode dives deep into the intersection of cannabis science, genomics, and biohacking. You'll discover how genetic polymorphisms influence mood, cognition, and stress response, and how personalized medicine can help you make smarter decisions around ketosis, fasting, and recovery. From optimizing the endocannabinoid system to hacking your biology for resilience and longevity, this is the future of functional medicine in action. You'll Learn: • How the endocannabinoid system regulates mood, focus, pain, and stress response • Which genetic polymorphisms affect cannabis sensitivity, anxiety risk, and dosing windows • How to use DNA testing to select cannabinoid and terpene ratios that fit your biology • Why delivery method matters and when sublingual dosing outperforms inhalation • How personalized cannabis protocols can support sleep optimization, recovery, and emotional regulation • The role of cannabinoids in mitochondrial function, neuroplasticity, and cognitive performance • How pharmacogenomics reduces antidepressant side effects and improves treatment matching • How to screen genetics for safer psychedelic use and avoid adverse reactions • What HLA and related markers reveal about mold sensitivity and inflammation This is essential listening for anyone serious about biohacking, brain optimization, longevity, anti-aging, functional medicine, and living Smarter Not Harder—with precision tools designed to upgrade your mind and body at the genetic level. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: cannabis biohacking, cannabis masterclass, Dave Asprey cannabis, DNA decoding, genetic testing for cannabis, personalized medicine, endocannabinoid system, cannabis genomics, cannabis and DNA, cannabis and genetics, cannabis nootropics, plant medicine biohacking, cannabis brain optimization, cannabis and neuroplasticity, cannabis for focus, cannabis and mitochondria, cannabis metabolism, cannabis for sleep, cannabis anti-aging, precision wellness, functional medicine, cannabis longevity, EndoDNA, Len May, cannabis and AI, biohacking genetics, cannabis and fasting, cannabis and ketosis, personalized supplements, cannabis and mood, cannabis stress response, genetic biohacking, cannabis cognitive performance Thank you to our sponsors! -Screenfit | Get your at-home eye training program for 40% off using code DAVE at https://www.screenfit.com/dave. -Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. -iRestore | Use code DAVE at https://www.irestore.com/ to unlock an exclusive discount on the iRestore Elite. Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 – Trailer • 1:25 – Introduction • 7:02 – Cannabis & The Endocannabinoid System • 13:30 – How It Works • 21:38 – Brain Health & Clinical Studies • 26:52 – Psychedelics & Genetic Testing • 31:37 – Genetics vs Epigenetics • 34:53 – Antidepressant Safety • 40:41 – Cannabis Success Stories • 46:02 – ADHD & Personality Genes • 50:54 – Mold, Nicotine & Mitochondria • 55:27 – GLP-1 & Metabolism • 1:00:34 – Microbiome & Medical Freedom See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Hydrogen is one of the most abundant elements in the universe, and according to today's guest, it's also one of the most misunderstood and underutilized when it comes to human health. I'm sitting down once again with Greg the Hydrogen Man, a molecular hydrogen expert, researcher, and host of the Uprising144K YouTube channel, to go deep into the truth behind hydrogen therapy.Greg shares the extraordinary story of how hydrogen helped him rise from a wheelchair-bound state and serious heart condition to full health, and why he believes purity and production methods make all the difference. He pulls back the curtain on industry misinformation, the corruption behind cheap machines, and why Japan is decades ahead of the US when it comes to hydrogen research and medical applications. Visit lukestorey.com/holyhydrogen and use code LUKE for $100 off the Lourdes Hydrofix.DISCLAIMER: This podcast is for educational purposes only and not intended for diagnosing or treating illnesses. The hosts disclaim responsibility for any adverse effects from using the information presented. Consult your healthcare provider before using referenced products. This podcast may include paid endorsements.THIS SHOW IS BROUGHT TO YOU BY:LITTLE SAINTS | Visit lukestorey.com/littlesaints and use code LUKE to get 20% off your first order. EONS | Visit lukestorey.com/eons and use code LUKE20 to save 20%.PIQUE | For a limited time, get 20% off for life + a free starter kit at piquelife.com/lukeFLFE | Try Focused Life-Force Energy for FREE for 15 days at lukestorey.com/flfeMORE ABOUT THIS EPISODE:(00:00:00) Uprising144K & Greg's Return(00:34:12) Clean Water First: Carbon Distillation, Minerals, & the Microbiome(00:45:34) Hydrogen as the Body's Shield Against Modern Stressors(00:53:31) Hydrogen, Mitochondria, & the Balance of Life(01:05:04) The Easiest Health Habit You're Not DoingResources:• Website: holyhydrogen.com • Instagram: instagram.com/uprising144k_ • Facebook: facebook.com/holyhydrogen • X: x.com/hydrogenman2 • X: x.com/holyhydrogen1 • TikTok: tiktok.com/@holy.hydrogen • YouTube: youtube.com/@UPRISING144K • YouTube: youtube.com/@HappyJapan-jh6zz • Rumble:

Send us a textA biophysical rethink of life, health, and disease through the lens of the Energy Resistance Principle (ERP).Episode Summary: A reframe of biology as energy flow through resistance rather than mere molecular machinery, introducing the Energy Resistance Principle (ERP): life requires a Goldilocks balance of electron flow from food to oxygen via mitochondria; too much or too little resistance drives aging, disease, and death. Explain mitochondria as energy transformers, link ERP to insulin resistance, psychiatric disorders, and healing, and explore health as a dynamic field-like state optimized by flux modulation.About the guest: Nirosha Murugan, PhD is a biophysicist studying how physical signals pattern biology to decode and reprogram health; Martin Picard, PhD is a mitochondrial psychobiologist at Columbia University, exploring how mitochondrial energy dynamics connect to human experiences, health, and healing. They collaborate on biophotons, light emission, and multi-scale energy signaling.Discussion Points:Mitochondria transform electrons from food into versatile electricity via proton gradients.Energy Resistance Principle: transformation needs resistance; chronic high resistance causes dissipative heat, damage, aging.GDF15 cytokine signals mitochondrial stress to brain, triggering energy conservation/mobilization.Insulin resistance: adaptive defense against electron overload, reversible by fasting/exercise.Psychiatric illness: excess brain energy resistance; exercise, keto, psychedelics redistribute flux.Health: dynamic optimization of energy resistance, not absence of disease.Healing: daily recovery from micro-damage via balanced resistance.Future: energy-based diagnostics/therapies (light, TMS) over molecule-only drugs.*Not medical advice.Reference Paper: The energy resistance principleRelated Episode:M&M 70: Mitochondria, Aging, Cellular Energy, Metabolism, Gray Hair Reversal & Brain-Body Communication | Martin PicardSupport the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

In this episode, Penny welcomes functional medicine expert Sharon Yeh — former clinical pharmacist turned mitochondrial and circadian wellness practitioner — to explore how simple but profound changes in light exposure, timing of meals, and environmental rhythms can unlock healing on every level: body, mind and soul.

Here I explain the lymphatic system, a crucial bodily network for overall health and appearance. I explain how the lymphatic system works to remove cellular waste and fluid from your organs and combat infections. I provide science-based tools that support your lymphatic system for the sake of health and appearance, including: how to reduce fluid retention in your limbs, trunk or face, how to eliminate 'bags' under your eyes and brain fog, and how to improve cardiac health and longevity. Because your lymphatic system lacks a central pump, it needs the mechanical forces generated by specific types of bodily movement, breathing and pressure to circulate your lymph properly, and I explain how you can activate these. I also explain how to support optimal functioning of your glymphatic system, a brain- and spinal cord waste-clearing system active during sleep that is crucial for brain functioning and longevity, including to prevent dementia. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AGZ by AG1: https://drinkagz.com/huberman LMNT: https://drinklmnt.com/huberman David: https://davidprotein.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman Timestamps (00:00:00) Lymphatic System (00:04:11) Circulatory System, Heart; Oxygen, Nutrient & Waste Transfer (00:11:03) Lymphatic System, Fluid, Lymphedema, Chronic Inflammation; Brain Fog (00:14:52) Sponsor: LMNT & David Protein (00:17:28) Lymphatic Vessels, Tool: Enhance Lymphatic Drainage with Movement (00:26:24) Tools: Jumping (Rebounding), Treading Water, Swimming (00:27:41) Tool: Swelling, Lymphatic Drainage & Diaphragmatic Breathing (00:32:05) Swimming & Lymphatic Flow; Tai Chi (00:34:00) Lymphatic Massage, Cancer & Lymphedema; Jade Roller & Gua Sha (00:37:28) Sponsor: AGZ by AG1 (00:38:56) Lymph Flow, Tool: Lymphatic Massage & Manual Lymphatic Drainage (00:45:02) Immune Function of Lymphatic System, Sore Lymph Nodes (00:54:24) Cancer Treatment, Lymph Nodes & Lymphedema (00:57:02) Limb Swelling, Minor Lymphedema & Inflammation, Lymphatic Boots (01:00:09) Sponsors: Eight Sleep (01:01:43) Glymphatic System, Brain & Sleep (01:05:56) Sleep & Brain Waste Recycling; Discovery of the Glymphatic System (01:12:24) Enhance Glymphatic Clearance, Brain Fog, Age, Tool: Side Sleeping Position (01:15:54) Tools: Optimize Sleep, Cardiovascular Exercise, Elevate Feet, Pillow (01:17:29) Puffy Face, Tool: Lymphatic & Facial Massage (01:21:23) Sponsor: Function (01:23:11) Tool: Hydration & Lymphatic Support (01:24:48) Tool: Cardiovascular Exercise & Lymphatic Vessels, Heart, Aging (01:31:06) Tool: Infrared & Red Light, Mitochondria, Lymphedema, Skin Appearance (01:36:08) Key Takeaways (01:37:21) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

Episode Highlights With SarahLight and leptin and how these interplay with each otherThe importance of leptin and what it isAll of our hormones are circadian How to support these hormones naturallyLeptin wasn't even discovered and studied until 1994 and why we still don't hear much about it even thought it is so importantHow this interplays with thyroid health and why this is important What it means when leptin is low or highThe mitochondrial aspect of these hormones and how light environment impacts thisHow much our light environment affects almost every aspect of healthMost important factors we can shift in our light environmentWhat to know about UV light and how much of each type of light we needWhat red and infrared light at sunrise and sunset do for hormones and mitochondriaWhy hunger in the morning is a good thing and important to haveRed light therapy panels don't have far infrared light and it is available in the sun daily! If our mitochondria think we are in danger, even if we have the perfect diet, they can down-regulate to keep us safe and how to signal safetyHer own amazing fertility journey and how these factors helped even when IVF failedThyroid specific advice for supporting the thyroid and tapering off medsHow a leptin reset can help and how to do itStrategies for timing food and carbs with the sun to get nourishment without gaining weightHer best tips for leptin reset and getting all these things into rangePerimenopause and how light and leptin come into playResources MentionedAll of Sarah's courses - Use code Katie for 15% offMyCircadianAppSarah's website, her Instagram, and YouTubeEvolving Wellness PodcastSarah's Free EbooksFunction Health lab testing

NEW! Support your strength and muscle goals with PUORI Creatine+ — a clean, effective creatine monohydrate supplement enhanced with taurine. Get 20% off at puori.com/VANESSA In this masterclass episode, Vanessa sits down with Dr. David Church, one of the most exciting young researchers in protein metabolism and a mentee of Dr. Arny Ferrando and Dr. Robert Wolfe. Together, they break down the latest science on protein timing, distribution, and supplementation — and how to apply it to achieve fat loss, preserve muscle, and enhance cognition. You'll learn: • How stable isotope tracer studies work and what they reveal about muscle protein synthesis (MPS). • The minimum protein per meal needed to trigger muscle growth and repair — and whether you can hit it with two meals a day. • The truth about intermittent fasting and muscle preservation — what happens to MPS in 2-meal and 1-meal-a-day patterns. • Why older adults and women over 40 face anabolic resistance and how EAAs (essential amino acids) can help overcome it. • What happens when you double your protein intake from 0.8 g/kg to 1.6 g/kg — and why distribution may matter less than total intake. • The surprising power of small doses of EAAs in muscle maintenance and cognitive support. • Why creatine is foundational for women, including new research showing benefits for brain health and sleep deprivation. • How to optimize body recomposition — burning fat while protecting lean mass — even during calorie restriction. • The difference between supplemental vs. replacement nutrition, and why EAAs work for older adults with low appetite. • The synergy of protein + resistance training + sleep + activity in driving sustainable fat loss. OneSkin is powered by the breakthrough peptide OS-01, the first ingredient proven to reduce skin's biological age. I use the OS-01 Face and Eye formulas daily—they've transformed my skin's smoothness, firmness, and glow. Visit oneskin.co/VANESSA and use code VANESSA for 15% off your first purchase Dr. Church also shares his own daily stack — including why he takes 20 g of creatine per day and combines it with EAAs for energy, cognition, and recovery — plus his favorite high-protein meals for busy days. If you've ever wondered how to burn fat efficiently while protecting every gram of muscle, this episode is packed with evidence-based takeaways you can implement right away. Mentioned in this Episode: • Puori Creatine + – clean, third-party-tested creatine monohydrate with taurine • Essential amino acids for older adults and women facing anabolic resistance • Stable isotope tracer studies — how we truly measure MPS • Protein targets: 1.6–2.4 g/kg depending on activity and energy restriction • Pre-sleep protein and its impact on overnight MPS and metabolic rate Get delicious high protein meal recipes! Connect with Vanessa on Instagram @ketogenicgirl Free High-Protein Keto Guide  Get 20% off on the Tone LUX Crystal Red Light Therapy Mask or the Tone Device breath ketone analyzer at https://ketogenicgirl.com with the code VANESSA Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.

While we're making progress in TREATING cancer, worldwide cancer INCIDENCE is soaring, especially among young people; New guidelines for colon cancer screening urge earlier start at age 45; Rates of peanut allergy are declining as more parents follow revised advice to introduce nuts earlier to kids; What's with all the buzz about methylene blue? Legalization and stronger pot are creating an epidemic of ER visits for uncontrolled vomiting, debilitating abdominal pain; New smart toilet gives you a report card on your poop; When Zoloft doesn't work for anxiety.

New study suggests taking thyroid medication WITH food may be just as good as taking it on an empty stomach; Natural support for Parkinson's Disease; Reviving the lost art of handwriting may be key to kid's learning; Dr. Jeffrey Bland does a deep dive on why not all fish oils are alike.

In this mind-expanding episode, Darin sits down with Dani Fontaine — researcher, practitioner, and expert on the human body's forgotten communication system: the endocannabinoid system. They unravel how this network regulates everything from mood and sleep to pain and consciousness — and why it was deliberately scrubbed from mainstream medical education. Dani reveals how cannabinoids, light, sound, and nature all communicate with our body's receptor fields — shaping the way we feel, heal, and perceive the world. Together they explore the profound spiritual and scientific implications of this hidden system, and how it connects us back to balance, nature, and truth.     What You'll Learn 00:00:00 - Welcome to the SuperLife Podcast 00:00:32 - Sponsor: Energy Bits 00:01:52 - Introducing Guest Danny Fontaine: Cannabis Pioneer and Plant Medicine Healer 00:04:54 - Deep Dive: What is the Endocannabinoid System (ECS)? 00:06:30 - ECS: The Homeostasis and Retrograde Signaling System 00:09:20 - ECS as a Receptive System for Subtle Energies and Environment 00:10:23 - Endocannabinoid System Toning (X-Tone) 00:12:58 - When the ECS Gets Worn and Depleted 00:16:34 - ECS Receptors on Every Cell, Fascia, and Neural Makeup 00:19:14 - How the ECS Breaks Down: The Impact of False Light 00:22:11 - The ECS and Non-Photon Rich Food 00:23:40 - Modulating the ECS Through the Six Senses (Touch and Breath) 00:24:38 - Mitochondria and ECS Receptors (MTK, CB1) 00:25:14 - Endogenous ECS and the Need for Proper Nutrients 00:27:11 - Cannabis as our Phyto Twin: The Plant Factor 00:27:57 - THC and the Suppression of Anandamide (Bliss Molecule) 00:31:44 - Sponsor: Fatty 15 00:35:25 - The Vast Amount of ECS Research & Medical Suppression 00:38:27 - Cannabinoids, Pain, and Individual Assessment 00:40:29 - Modulating ECS with Nature: Terpenes like Pinene 00:42:51 - Olfactory System as the Most Sophisticated Input 00:47:03 - ECS as the "Microscope Moment" for Health 00:48:23 - Pinene, CB1, and TRP Receptors in Pain Management 00:50:39 - The ECS, Collagen, and Hyaluronic Acid Fluctuation 00:51:44 - Working with the ECS for Faster Results (Cancer and Genetic Mutations) 00:55:06 - Sponsor: SuperLife Patreon 00:56:39 - Measuring the ECS with Bio-Field Technology 00:57:29 - The Danger of THC Stacking and Immunosuppression 00:59:30 - Overwhelmed Cells and Fake Inputs 01:00:12 - Hemp as a Homeostasis Plant for the Planet (Soil Remediation/Carbon) 01:02:06 - ECS Strength in Animals vs. Humans 01:04:08 - Why Cannabis and Hemp Were Suppressed 01:07:07 - The Historical Use of Cannabis in Medicine 01:08:12 - Hemp's Nutritional Profile (Amino Acids and Omegas) 01:09:37 - Ayahuasca, Receptor Overexpression, and Looping 01:13:33 - Importance of ECS Knowledge and Application 01:14:58 - Exercise, Anandamide, and ECS Toning 01:15:22 - Cold Plunge and Shocking the ECS and Hormones 01:17:16 - Takeaways: Light, Movement, Sound, and Breath 01:21:41 - ECS: The Main Signaling and Communication System 01:23:28 - Final Thoughts: ECS as the Conduit to Self and Spirit     Thank You to Our Sponsors: Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout. EnergyBits: Get 20% off your entire order by going to https://energybits.com/ and using code DARIN at checkout.     Find More from Dani Fontaine Instagram: @danifontaine Website: danifontaine.com Products: Try Dani's Nature Root     Connect with Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com     Key Takeaway “Your endocannabinoid system isn't just a biology lesson — it's a bridge between your body and the universe. When you feed it light, breath, and truth, you remember what balance actually feels like.”

Beat BLOAT & unlock better protein absorption and digestion with MassZymes by BiOptimizers. NOW GET 15% off your order with the code VANESSA at bioptimizers.com/vanessa What separates people who keep fat off from those who regain it? In this episode, Vanessa Spina breaks down the latest research on long-term fat loss maintenance — including insights from one of the world's most respected obesity and metabolism researchers, Dr. James Hill. You'll learn the proven strategies that help preserve lean muscle, protect metabolism, and create sustainable fat loss — all backed by decades of science. Vanessa unpacks Dr. Hill's three-bucket model for lasting success, showing how to combine nutrition, activity, and mindset into a lifelong blueprint for body recomposition and metabolic health. Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa In this episode, you'll discover: • Why losing fat and keeping it off require two completely different skill sets • The research-backed protein and training strategies that preserve lean muscle • How small daily changes — like 100 fewer calories or 2,000 more steps — compound over time • Why exercise “fixes” your metabolism and helps you stay lean for life • The concept of your appetite sweet spot — and how to find it • How to shift from a “victim” to “voyager” mindset and make maintenance effortless • Dr. Hill's insights on GLP-1 medications and how to transition off without regaining weight If you've ever lost weight and struggled to maintain it, this episode will show you the science of what truly works — and how to protect your lean mass, metabolism, and confidence for the long term. Get my free NEW high-protein keto guide: The Keto Reset eBook Learn more about the TONE LUX Crystal red light therapy mask and the accessory the TONE LUX CONTOUR for the neck and décolleté and get 20% OFF with the code VANESSA Free high-protein keto guide: The Keto Reset eBook

Modern joint pain isn't just wear and tear—it's a systemic, metabolic disease that starts years before symptoms show. In this episode, you'll learn how inflammation, mitochondria dysfunction, and immune imbalance trigger cartilage loss… and how to reverse it using targeted cytokine modulation, cellular regeneration, and smarter supplements for longevity and human performance. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Kiran Krishnan, a research microbiologist and Chief Scientific Officer at Calroy Health Sciences. He's the founder of Microbiome Labs—one of the most trusted microbiome-focused brands in functional medicine—and a formulator behind cutting-edge supplements like Arterosil and Vascanox. With over two decades of experience, Kiran has launched multiple health ventures, authored scientific textbook chapters, published clinical trials, and holds global patents in human health. He's a leading authority on systemic inflammation, mitochondrial dysfunction, and gut-driven disease—and one of the few voices making complex biology accessible for real-world results. He breaks down their new supplement Cartigenix HP, and how cytokines like IL-6 and TNF-alpha flip your cartilage cells from anabolic repair to catabolic destruction, how mitochondrial decline speeds up joint damage, and why most modern painkillers make your joints worse. You'll learn how a specialized blend of boswellia and celery seed reprograms inflammation, why walking beats medication in clinical trials, and how fasting, nitric oxide, and gut health work together to optimize joint regeneration. You'll learn: • How cartilage cells (chondrocytes) rely on mitochondria for tissue repair • Why global cytokines like IL-6 and TNF-alpha drive joint degradation and brain fog • How cartilage begins to break down in your teens—and what to do about it now • The surprising clinical data on walking distance, inflammation markers, and recovery • Why most supplements and NSAIDs fail—and what actually rebuilds joints • How diet and leaky gut create 5-day inflammation spikes from a single fast-food meal • The mitochondrial link between joint pain, cardiovascular risk, and depression • Why perimenopausal women are at 10x higher risk for arthritis—and how to prevent it • How to track your biological joint age using imaging and systemic inflammation labs This is essential listening for anyone serious about biohacking, functional medicine, pain-free aging, and human performance. Whether you're lifting heavy, walking daily, or just trying to stay mobile into old age, this episode gives you the science and tools to reverse joint degeneration and extend your healthspan. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Joint cartilage regeneration, IL-6 inflammation suppression, TNF-alpha cytokine modulation, Chondrocyte mitochondrial repair, Catabolic to anabolic tissue shift, Osteoarthritis reversal, Rheumatoid arthritis inflammation, Mitochondria and collagen synthesis, Boswellia seratol extract, Celery seed COX inhibition, Matrix metalloproteinase (MMP) inhibition, Synovial fluid inflammation, Leaky gut and joint pain, Six-minute walk test improvement, Global cytokine markers, High sensitivity CRP reduction, ESR sedimentation rate, Uric acid crystal formation, Post-prandial glucose walking, Cartilage MRI biomarkers, Functional medicine joint support, Fasted repair stacking, Vasodilation and nitric oxide, Anti-inflammatory supplement stacking, NF-kB pathway reduction, Joint space biological age, Microvascular circulation and cartilage, Caloric load and cytokine spike, Perimenopause and arthritis risk, Joint tissue anabolic activation **Get an exclusive discount for podcast listeners at calroy.com/dave : https://calroy.com/product/cartigenix-hp/?lp=dave ** Thank you to our sponsors! -BodyGuardz | Visit https://www.bodyguardz.com/ and use code DAVE for 25% off. -BiOptimizers | Go to http://bioptimizers.com/dave and use code DAVE15 to get 15% off your order. -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. -Caldera + Lab | Go to https://calderalab.com/DAVE and use code DAVE at checkout for 20% off your first order. Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:25 — Introduction 2:01 — Why Modern Medicine Fails at Joint Pain 3:07 — Painkillers That Accelerate Joint Damage 7:35 — Rheumatoid vs. Osteoarthritis Explained 8:54 — Cytokines That Destroy Cartilage 12:10 — Arthritis Begins in Your Teens 15:35 — 75% Pain Reduction in 7 Days 18:35 — The Science Behind Boswellia & Celery Seed 24:10 — Six-Minute Walk Test Results 25:45 — The $200/Month Painkiller Trap 28:53 — Proof Cartilage Can Regrow 31:01 — Mitochondria and Joint Repair 32:29 — Inflammation Links to Heart Disease 35:52 — Why Glucosamine Doesn't Work 37:07 — Silent Arthritis in 90% of Adults 40:44 — Why Women Face Higher Joint Risk After 40 45:52 — Food as the #1 Inflammation Trigger 47:23 — Fasting & Cartogenics Stack for Repair 50:27 — Movement Snacks and Efficient Training 55:54 — Why Joints Heal Slower Than Muscles 57:48 — Dave's Stack and Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Biohacking isn't just food + exercise, it's about fixing the invisible disruptors wrecking your biology. EMFs, mold, toxins, mitochondrial stress, these are the real reasons you still feel tired, foggy, or inflamed even on a perfect diet. I've been there. I lost 100 lbs, built Bulletproof Coffee, and discovered why food alone isn't enough. In this video, I'll show you what's actually holding back your energy, focus, and longevity… and how to finally feel truly bulletproof.Chapters:0:00 – Introduction1:30 – The hidden disruptors wrecking your health2:15 – EMFs: invisible energy thieves3:00 – Mold exposure: the silent killer in your home4:00 – How toxins block your nutrients5:10 – Mitochondria: the real source of energy6:20 – Detox hacks that actually work7:30 – Binders: the secret to flushing toxins8:30 – Rebuilding nutrients for lasting energy9:20 – The missing biological switch: nervous system safety10:30 – Resetting your circadian rhythm naturally11:30 – Box breathing: a biohack for instant calm12:20 – Gratitude, digestion & unlocking thrival modeConnect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/Danger Coffee: https://dangercoffee.com/DAVE15Dave Asprey's BEYOND Conference: https://beyondconference.com/Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15Upgrade Collective: https://www.ourupgradecollective.comUpgrade Labs: https://upgradelabs.com40 Years of Zen: https://40yearsofzen.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.