Podcasts about mitochondria

Most energy drinks trade your long-term health for a short-term jolt. This episode breaks down a smarter approach to energy, one that builds mitochondria function, supports gut health, stabilizes mood, and helps you sleep better at night, all without the crash -Get 15% off your next order at: https://getmte.com/dave Host Dave Asprey sits down with Jeff Boyd, founder and chairman of MTE (More Than Energy), the caffeine-free energy drink built around adaptogens, nootropics, and prebiotics that delivers what Boyd calls "energy that loves you back." Before launching MTE, Jeff spent 15 years as President and co-owner of Luggage Free, scaling the company to operations in over 100 countries before selling it in 2019. He brings the operational discipline of a veteran entrepreneur and the personal conviction of someone who built the energy product he actually wanted to exist. Dave and Jeff get into the full science and strategy behind MTE's ingredient stack, including paraxanthine, ashwagandha, eleuthero, maca, GABA, theanine, and saffron, and why each one was chosen for its role in stress response, brain optimization, and sleep optimization. They also dig into the formulation challenges of building a clean-label supplement over a stimulant base, the real difference between caffeine and its downstream metabolite paraxanthine, and why this blend functions more like a foundational biohacking protocol than a beverage. You'll Learn: Why conventional energy drinks wreck your cortisol curve and what to do instead How paraxanthine delivers the benefits of caffeine without the jitters or sleep disruption The adaptogen trio (ashwagandha, eleuthero, and maca) and how they work together for stress response and human performance Why saffron is one of the most underrated nootropics for mood and brain optimization How gut health and the microbiome connect directly to your energy, metabolism, and longevity The mitochondria connection between willpower, physical performance, and entrepreneurial output How AI is reshaping small teams and what founders need to do right now to stay competitive Why the cleanest path to anti-aging and longevity starts with how you manage your energy across the day Thank you to our sponsors! - Beyond Wonderland Conference | Oct 13 - 14, 2026. Get your ticket now at wonderlandconference.com. - Gatlan | Book your free consultation at www.gatlan.com/DAVE - BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle. - Danger Coffee | Grab yours at DangerCoffee.comand use code DAVEPOD at checkout for 15% off. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Jeff Boyd, MTE, More Than Energy, caffeine-free energy, paraxanthine, adaptogens, ashwagandha, eleuthero, maca, nootropics, saffron, GABA, theanine, prebiotics, gut health, stress response, cortisol management, sleep optimization, huckleberry acai, clean label formulation, stevia Reb A, energy drink alternative, paraxanthine vs caffeine, afternoon energy, Luggage Free, cycling endurance, long jump training, ADHD entrepreneurship, AI small teams, willpower mitochondria Resources: • Get 15% off your next order at: https://getmte.com/dave • Purchase Dr. Fotuhi's New Book The Invincible Brain: https://a.co/d/0iHCgPpL • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:42 – What Is MTE? 03:50 – Ingredients Deep Dive 09:49 – Flavors & Formulation 12:31 – Dave's Caffeine Origin 18:35 – Athletic Identity 22:38 – ADHD & Entrepreneurship 26:43 – AI & Future of Work 30:47 – Willpower & Mitochondria 35:34 – MTE Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Curious whether peptide therapy is the missing piece in your wellness routine, or just another overhyped trend? This episode breaks down what these powerful chemical messengers do in the body, from healing injuries to balancing brain chemistry, cellular energy and more, plus why sourcing and dosing make all the difference.Host Jenn Trepeck sits down with Dr. Aleksandra Gajer to explore BPC 157, brain-supporting peptides, and mitochondrial function, while tackling how to use peptides safely, who should avoid them, and why they work best as a tool rather than a magic fix-all.What You Will Learn in This Episode:✅ How peptide therapy acts as a chemical messenger system that supports the body's own healing pathways rather than overriding them✅ Why BPC 157 has become one of the most talked about peptides for tendon repair, gut healing, and recovery✅ How neuroinflammation, not just neurotransmitter imbalance, may be driving anxiety, depression, and brain fog✅ The role of mitochondrial function and insulin sensitivity in body composition, energy, and long-term metabolic healthThe Salad With a Side of Fries podcast, hosted by Jenn Trepeck, explores real-life wellness and weight-loss topics, debunking myths, misinformation, and flawed science surrounding nutrition and the food industry. Let's dive into wellness and weight loss for real life, including drinking, eating out, and skipping the grocery store.TIMESTAMPS:00:00 Dr. Aleksandra Gajer's path from emergency medicine to proactive, personalized healthcare08:04 Defining peptides and their relationship to inflammation and healing10:04 Exploring BPC 157 for tendon injury, gut healing, and tissue recovery12:31 How peptides support autoimmune conditions by regulating immune balance15:35 Brain peptides Selank and Semax and the truth behind the neuroinflammation link to anxiety18:57 Understanding mitochondrial function, fatigue, and brain fog as cellular energy issues20:35 MOTS-c, insulin sensitivity, and the connection to body composition22:18 Why peptides work best as a tool, not a replacement for healthy habits26:03 Safe peptide sourcing, endotoxins, and who should avoid peptide therapy33:54 Hormone health, dosing strategy, and cycling peptides for sustainable resultsKEY TAKEAWAYS:

This week I interviewed Dr. Adrijana Kekic!  She is the founder of Futurama, which applies integrated genetic, metabolic, and molecular analysis to individuals who look healthy on paper but feel metabolically stuck, fatigued, or inflamed. We discussed the concept of “cellular drift”, and how dysfunction progresses silently despite normal labs along with: - the importance of understanding fasting insulin  - how she leverages AI to create your roadmap to health - the benefits and downsides to peptidesand her one tip to get your body back to what it once was!Connect with Dr. Kekic: https://www.futurome.com/---FREE Pro-Metabolic Window Eating Guide:https://brian-getleaneatclean.beehiiv.com/subscribeClick to book a FREE 15 minute consult with Brian:https://calendly.com/bdgryn/15min----Interested in Upgrading your Mitochondria, Improving Energy and Sleep! Check out Troscriptions: https://bit.ly/4ik5kK5Use Discount Code for 10% OFF: EATCLEAN----If you're serious about building strength and muscle while protecting your joints, grab the B Strong Blood Flow Restriction bands I use and recommend:Go Here: https://bit.ly/4ektMvGUse Coupon Code: BRIANGRYN-----How to Take Simple Steps to Reclaim the Body, Energy, and Strength You Had 10-15 Years Ago Using My Stepladder System:https://www.stepladdersystem.com/----B.rad Whey Protein Isolate Superfuel:The Best Protein on The Planet! Available in Two Delicious Flavors: Vanilla Bean and Cocoa BeanUse Coupon Code glec10off for 10% off your order!https://a.co/d/731gssV----My favorite health bars with clean ingredients!https://www.eatprima.com/BRIAN6816310% OFF with this link!

What if fatigue, brain fog, slow recovery, and burnout aren't simply a lack of motivation—but a reflection of what's happening deep within your cells? In this Wellness Illuminated episode of Light Body Radio, Dr. Lara May explores the fascinating world of mitochondrial health, cellular energy production, and the role peptides can play in supporting resilience, healing, and healthy aging. You'll learn how the body creates ATP—the cellular energy currency that powers every process in the body—and why mitochondrial function is essential for everything from brain health and detoxification to recovery and repair. Dr. Lara also breaks down the relationship between NAD+, methylene blue, mitochondrial signaling, and why more isn't always better when it comes to supporting energy pathways. This episode offers a practical, science-informed look at how cellular energy impacts overall health and what it means to support your body intelligently rather than simply chasing more energy. © Light Body Radio-Podcast, 2026. All rights reserved. This podcast features background music by ScottHolmes Music. We have obtained the necessary licenses for the use of this music. Our license was renewed on May 7, 2024, and we have been using ScottHolmes Music since 2017. Unauthorized use or distribution of this podcast, including but not limited to the background music, is strictly prohibited and may result in legal action. For more information or to request permissions, please contact scott@scottholmesmusic.com.

From fermented foods to Epsom salts and omega-3s, Dr. Seneff outlines how to defend your body from glyphosate and deuterium. #MitochondriaSupport #DetoxStrategies #GlyphosateDefense #HealthTalks

What if the secret to overcoming chronic fatigue, brain fog, and cellular aging lies within your mitochondria? In this episode of The Better Life, host Dr. Mary Ann Pinkston sits down with international speaker, researcher, and cellular medicine expert Dr. Gordon Crozier from the Crozier Clinic. Together, they dive deep beneath the surface of traditional medicine to explore how integrative, evidence-based approaches can truly revitalize your health. If you’ve been slamming methylated B vitamins for MTHFR mutations but still feel completely exhausted, this conversation is the missing piece of your puzzle. What You’ll Learn in This Episode: The Truth About NAD+: Why this vital cellular coenzyme is essential for DNA repair, intense detoxification, and mitochondrial energy. NAD+ vs. Precursors: The difference between raw IV NAD+ (and why it causes nausea) versus cutting-edge precursors like NMN and True Niagen. The Magic of Methylene Blue: How this powerful antiviral compound works in concert with NAD+ to supercharge the electron transport chain—and why you must take structured breaks from it. Deep-Dive Methylation: Why methylation goes far beyond MTHFR, impacting hormone breakdown, breast and prostate cancer prevention, and neurodegenerative risks. Natural NAD+ Boosters: How everyday habits like proper weight management, targeted protein intake, and consistent exercise naturally elevate your levels. The Danger of "Supplement Overload": Why less is often more, and the hidden risks of buying non-third-party tested supplements off the shelf. Important Safety Note: Dr. Crozier explains why compounding quality matters and highlights critical contraindications for Methylene Blue, including SSRIs (Serotonin Syndrome risk) and G6PD deficiencies. Connect with the Experts: Find Dr. Gordon Crozier: Learn more about his practice, research, and social media at CrozierClinic.com. Find Dr. Mary Ann Pinkston: Access past episodes, resources, and links discussed in today's show at drpbetterlife.com. See omnystudio.com/listener for privacy information.

What if inflammation is the missing link behind so many of the symptoms women experience after 40? In this solo episode, Dr. Mariza breaks down the powerful connection between low-grade chronic inflammation, metabolic dysfunction, hormone changes, brain health, energy production, and accelerated aging. She explains why inflammation is far more than an immune system issue and how it silently influences nearly every aspect of health during perimenopause and menopause. Many women assume that fatigue, brain fog, stubborn belly fat, poor sleep, anxiety, joint pain, cravings, and declining energy are separate issues requiring separate solutions. But Dr. Mariza reveals how these symptoms are often interconnected through one common underlying process: inflammation. She also explores why perimenopause is not simply a hormone transition but a metabolic, vascular, and neuroendocrine transition that increases inflammatory burden and changes how the body responds to stress, blood sugar fluctuations, sleep disruption, and hormonal shifts. Most importantly, Dr. Mariza shares the practical lifestyle pillars she uses to lower inflammation, improve metabolic flexibility, support hormone health, and create the internal environment needed for healthy aging and long-term vitality. If you've been feeling like your body is changing but can't quite connect the dots, this episode will help you understand what inflammation may be trying to tell you. IN THIS EPISODE Why low-grade inflammation is one of the biggest drivers of symptoms after 40 The connection between inflammation, metabolism, hormones, and aging How perimenopause increases inflammatory burden throughout the body The labs Dr. Mariza recommends to assess inflammation and metabolic health Why blood sugar regulation is one of the fastest ways to lower inflammation The critical role of muscle, movement, sleep, and nervous system regulation How gut health influences inflammation, immunity, and metabolism Practical daily habits that help reduce inflammation and support healthy aging QUOTES“The goal isn't simply to lose weight. The goal is creating an internal environment where the body no longer feels the need to stay inflamed.” “One workout cannot undo eight hours of sitting.” “When inflammation comes down, everything goes up.” RESOURCES MENTIONED Use code ENERGIZED and get 10% off on your MitoQ Order https://www.mitoq.com/energized%C2%A0 ⁠Order my newest book: The Perimenopause Revolution https://peri-revolution.com/ Fix Your Metabolism Masterclass Joi & Blokes Lab Testing Blood Sugar Hacks Guide RELATED EPISODES  755: What If Your Body Isn't Broken, Just Undernourished? The Missing Link Between Nutrients, Hormones & Energy with Ryan Woodburry 753: The Brain's Hidden Role in Chronic Pain, Migraines & Fatigue with Dr. Howard Schubiner 751: Bloating, Brain Fog & Hormone Chaos? Your Gut May Be the Root Cause with Dr. Cassie Smith 741: Estrogen, Gut Health, Mitochondria, and Cardiovascular Health: What Changes In Perimenopause with Dr. Siobhan Mitchel

Send us Fan MailThe possible role of deuterium (heavy isotope of hydrogen) in regulating cell division, mitochondrial metabolism & cancer.TOPICS DISCUSSED:Deuterium Basics: Deuterium is twice as massive as regular hydrogen; natural water contains ~150 ppm, with stronger oxygen-deuterium bonds slowing reactions compared to oxygen-hydrogen.Mitochondrial Role: Healthy mitochondria produce deuterium-depleted metabolic water (~110 ppm from fat oxidation vs. ~150 ppm from carbs), helping maintain low cellular D:H ratios.Cell Growth Regulation: Lower deuterium slows cell division in vitro; cells sense small D:H changes, with higher levels (near/above 150 ppm) promoting growth.In Vitro Evidence: DDW (e.g., 25-125 ppm) can reduce proliferation and alters cancer-related gene expression.Animal Models: DDW caused tumor regression in mice with transplanted human cancers and showed possible efficacy in veterinary use for dogs and cats.Human Prostate Cancer: Phase 2 randomized study showed greater Prostate-Specific Antigen (PSA) reduction, tumor shrinkage, and better 1-year survival with DDW plus standard therapy vs. placebo.Dietary Modulation: Ketogenic/high-fat diets lower body deuterium from lipid oxidation.Broader Implications: Potential in neurodegeneration models; larger trials needed for registration as adjunct cancer therapy.ABOUT THE GUEST: Gábor Somlyai, PhD is a molecular biologist who pioneered deuterium depletion studies at the National Institute of Oncology in Hungary. His primary work focuses on the role of deuterium in living organisms and the development of deuterium-depleted water for cancer therapy.Support the showHealth Products by M&M Partners:AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models.OmegaQuant: At-home blood testing to see fatty acid profiles, including omega-3 fatty acids. Use link to see options and support M&M.SiPhox Health: Comprehensive, cost-effective bloodwork from the comfort of home. Use code TRIKOMES for 20% off.KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off.For all the ways you can support my efforts

What if a single peptide could reset thousands of the genes that age you? GHK copper has been quietly running most of your regenerative biology since the day you were born. And by 60, more than half of it is gone.In this deep dive, Dr. Joy Kong, the Stem Cell Queen and a triple board-certified regenerative medicine physician, walks through the science of GHK copper: a naturally occurring three-amino-acid peptide bound to a copper ion, first identified in 1973 by Dr. Loren Pickart, who observed aged liver cells regaining youthful function after exposure to young human plasma. The episode covers GHK copper's two primary mechanisms (copper delivery and gene-level bioregulation capable of shifting thousands of human genes back toward youthful expression) and its application across skin remodeling, wound healing, hair growth, neuroprotection (BDNF support, neural inflammation, anti-anxiety effects), ATP production, mitochondrial function, and stem cell reactivation. Dr. Joy reviews practical methods including topical formulations, subcutaneous injection, microneedling combinations, cost considerations, stability with other actives like vitamin C, and the protocols she uses in her own clinical practice at Chara Health in Los Angeles.GHK copper is one of the few peptides shown to switch dormant stem cells back into active proliferation, support the brain against oxidative damage, and rebuild skin from the dermis up. It works at the gene level, which is what makes it different from nearly every other anti-aging compound on the market.If you've been curious about peptides but overwhelmed by the marketing, this is the breakdown to start with.✨ Shop CharaOmni, my stem cell skincare line: https://www.charaomni.com/ Dr. Joy talks about:00:00 What GHK-Cu Does in the Body01:15 GHK-Cu Discovery: Dr. Loren Pickart, 1973, and Why Levels Crash by 6002:10 The Two Mechanisms: Copper Delivery and Genetic Bioregulation03:45 GHK-Cu for Skin, Wound Healing, and Hair Growth05:55 GHK-Cu for the Brain: BDNF, SOD1, and Anti-Anxiety Effects07:25 GHK-Cu for ATP, Mitochondria, and Stem Cell Activation08:40 Topical, Subcutaneous, and Microneedling Protocols11:15 Cost, Stability, and the Vitamin C InteractionAdditional Resources✨ Visit My Clinic: Chara Health

We've been taught to treat chronic diseases as isolated problems to be diagnosed and managed. But these conditions may have more in common than conventional medicine has traditionally recognized. On this episode of The Dr. Hyman Show, I'm joined by physician and researcher Dr. Terry Wahls, who transformed her understanding of disease after developing progressive multiple sclerosis. We discuss the emerging science behind mitochondria, inflammation, nutrition, the microbiome, and why creating health may be just as important as treating disease itself. We explore: What Dr. Wahls discovered about cellular health while searching for answers beyond conventional treatment Why mitochondria may play a central role in conditions like MS, Alzheimer's, Parkinson's, depression, and chronic fatigue How food, sleep, movement, and stress directly influence inflammation, energy production, and brain health Why focusing only on symptom suppression may overlook the deeper biological dysfunction driving chronic disease What “creating health” actually looks like in practice—and how small daily habits can influence how you feel and function over time What makes this conversation so compelling is that Dr. Wahls' story challenges many of the assumptions we have about chronic disease and recovery. For me, it really highlights how profoundly nutrition, sleep, movement, and stress can shape the body's ability to adapt and recover over time. View Show Notes From This Episode Sign up for Dr. Hyman's Brainshaping Academy to learn how to nourish the biological systems that support your mental, emotional, and cognitive health https://drhyman.com/products/brainshaping?utm_source=dr_hyman_show&utm_medium=newsletter&utm_campaign=may_27&utm_content=link Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman's Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Healthhttps://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive This episode is brought to you by fatty15, Big Bold Health, Timeline, BON CHARGE, BIOptimizers, and Made In. Head to fatty15.com/HYMAN today and use code HYMAN for 15% off your 90-day subscription Starter Kit. Go to bigboldhealth.com/drhyman and use code HYMAN15 to save 15% on your first order. Visit timeline.com/drhyman for 20% off a subscription on top of the new starting price of $79. Head to boncharge.com/hyman and use code HYMAN for 15% off. Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%. Visit madeincookware.com and use code HYMAN10 for 10% off your order. (0:00) Dr. Terry Wahls' illness journey, Dr. Mark Hyman's intro, and sponsor mentions (2:54) Dr. Wahls and Dr. Hyman discuss their medical histories (4:00) Dr. Wahls' experience with multiple sclerosis (7:08) Dietary changes and physical improvements (9:09) Environmental factors in autoimmune diseases (11:17) Resistance in the medical system to new approaches (12:26) Integrating basic science into clinical practice (15:32) Mitochondrial support supplements (20:24) Mitochondria's role in energy-intensive tissues (22:11) Functional medicine and Dr. Wahls' continued health journey (23:49) Nutrient-focused dietary approach and recovery (26:13) Development and application of the Wahls diet (27:35) Nutrient-rich food categories and health benefits (30:11) NIH funding and functional medicine research potential (34:00) Success stories from the therapeutic lifestyle clinic (39:28) Creating health versus treating disease (44:10) Expanding research to other chronic illnesses (45:40) Latest clinical trials and future research directions (47:49) Advances in chronic disease treatment science (49:05) Predicting diet effectiveness: microbiome and genetics (50:00) Microbiome research and multiple sclerosis (51:18) A new theory of human biology in medicine (53:01) Creating health through lifestyle changes (55:13) Need for multimodal interventions in research (58:20) Funding challenges and philanthropy's role (59:08) Comprehensive approaches to complex diseases (1:01:05) Potential to reverse genetic diseases with lifestyle changes (1:07:24) Strategies for creating a healthy human (1:08:01) Upcoming research and initiatives by Dr. Wahls

What if one of the biggest missing pieces of perimenopause isn't hormones at all? In this eye-opening conversation, Dr. Mariza sits down with Ryan Woodbury, co-founder and co-CEO of Needed, to explore why nutrient deficiencies may be one of the most overlooked drivers of fatigue, brain fog, low energy, poor stress resilience, and other common symptoms women experience during perimenopause. Ryan shares the surprising personal experience that led her into the world of nutritional science and supplementation, including discovering her own nutrient deficiencies despite following a highly nutrient-dense diet. Together, they unpack the alarming research showing that most women are entering pregnancy, postpartum, and eventually perimenopause already running on depleted nutritional reserves. They discuss the shortcomings of traditional nutritional recommendations, why so many women remain deficient despite taking standard multivitamins, and how decades of stress, caregiving, disrupted sleep, pregnancies, and modern environmental demands create a perfect storm for depletion. Dr. Mariza and Ryan also dive into the critical role nutrients play in supporting hormone production, brain function, metabolism, cellular energy, blood sugar regulation, and healthy aging. Most importantly, they offer practical guidance for building a stronger nutritional foundation so women can thrive through midlife and beyond. If you've ever wondered why you still feel depleted despite doing "all the right things," this conversation will help connect the dots. RYAN WOODBURY Ryan Woodbury is the co-founder and co-CEO of Needed, a company dedicated to improving nutritional support for women across every stage of life. With a background in environmental science, nutrition, and food systems, Ryan has become a leading advocate for evidence-based nutrient support for fertility, pregnancy, postpartum, and perimenopause. Her mission is to help women move beyond bare-minimum nutrition and build the foundation needed for lifelong vitality. IN THIS EPISODE Why nutrient deficiencies are so common among women entering perimenopause The hidden impact of stress, caregiving, pregnancy, and postpartum depletion Why traditional multivitamins often fail to meet women's nutritional needs The critical role of vitamin D, magnesium, choline, omega-3s, and B vitamins How nutrient deficiencies contribute to fatigue, brain fog, and metabolic dysfunction Why foundational nutrition matters before adding targeted interventions The connection between blood sugar regulation, inflammation, and hormonal health How women can build a stronger foundation for energy, cognition, and healthy aging QUOTES“95% of women have at least one nutrient deficiency in a very key nutrient.” “You deserve to get what your body actually needs, not the bare minimum.” “When women reclaim their energy, they don't just change themselves, they change the world.” RESOURCES MENTIONED Subscribe now and get 20% off + FREE Shipping on your first NEEDED Supplement Order http://thisisneeded.com/DrMarizaSnyder Order my newest book: The Perimenopause Revolution https://peri-revolution.com/ Needed Website Needed InstagramNeeded Facebook Needed Academy Instagram RELATED EPISODES 754: How to Find Joy When Life Doesn't Go According to Plan with Amberly Lago 751: Bloating, Brain Fog & Hormone Chaos? Your Gut May Be the Root Cause with Dr. Cassie Smith 741: Estrogen, Gut Health, Mitochondria, and Cardiovascular Health: What Changes In Perimenopause with Dr. Siobhan Mitchel 743: Why Your Heart Risk Changes in Menopause (And What You Can Do About It) with Dr. Jayne Morgan

I sit down with nutrition scientist Dr. Luke Bucci to explore the powerful connection between blood flow, nitric oxide, mitochondrial health, and healthy aging. We discuss why circulation impacts nearly every function in the body, what causes energy levels to decline with age, and how nutrition, exercise, and targeted supplementation may help support long-term vitality. Dr. Bucci also explains the science behind nitric oxide, blood sugar regulation, and the role mitochondria play in keeping us energized and resilient throughout life.Dr. Luke Bucci, PhD, CNS, CCN is the Chief Scientific Officer of Juvenon and a biomedical scientist with more than 40 years of experience in nutrition, dietary supplements, and clinical laboratory science. He earned his PhD in Biomedical Sciences from the University of Texas Health Science Center at Houston and has helped develop numerous patented nutritional products used worldwide. A recognized authority in healthy aging, sports nutrition, omega-3s, probiotics, and dietary supplement science, Dr. Bucci has authored scientific books, taught university-level courses, and received multiple industry awards for his contributions to nutrition and health innovation.Links mentioned during this episode:Juvenon: https://juvenon.com/Free Initial Consultation with Dr. Megan: https://p.bttr.to/3a9lfYkLyons' Share Instagram: www.instagram.com/thelyonsshareJoin Megan's newsletter: www.thelyonsshare.org/newsletter

Send us Fan MailWhat if the key to calming your nervous system, sleeping deeper, and healing from the inside out was as simple as light?In this episode, host Jen sits down with Kristen Spielman—registered nurse and longevity specialist—to explore the science of red light therapy and photobiomodulation. Together, they unpack how cellular energy directly impacts your nervous system, why chronic inflammation fuels anxiety, and how red and near-infrared light can help your body shift out of fight-or-flight mode and into true rest and repair.Whether you're struggling with chronic stress, poor sleep, or pain—or simply looking to glow from the inside out—this conversation will leave you inspired and informed.To purchase face ($395) mask, email info@vitaeskin.com mention Exalted Health for $50 off. Red light belt How's My Nervous System Quiz     I Connect with us at Exalted Health

Are you suffering from chronic "adult tiredness," or wondering why you immediately get sick the second you finally go on vacation? In this episode of Beauty Bytes, I am joined by Dr. Scott Sherr, a board-certified internal medicine physician, specialist in hyperbaric oxygen therapy, and leader in health optimization medicine. We are doing a massive deep dive into the true powerhouse of your cells: the mitochondria. With only 6% of the US population having optimized mitochondrial function, it is no wonder so many of us are completely exhausted. Dr. Sherr explains why the traditional approach to feeling better is backward, revealing why you must fix your cellular energy before trying to lower your stress and anxiety. We also talk about a fascinating synthetic compound called methylene blue. Dr. Sherr explores how taking it via buccal troches can hack jet lag, eliminate brain fog, and safely jumpstart your biological system. Plus, we cover the real science of hyperbaric oxygen therapy and why your skin is actually your "reverse gut".Guest Information: Dr. Scott Sherr is the Chief Medical Officer of Troscriptions and One Base Health. You can find his products at troscriptions.com and learn more about his health optimization practice at drscottsherr.com.

What Causes Cancer? The Truth Most Doctors Don't Talk AboutIn this episode of Intellectual Medicine, Dr. Stephen Petteruti explores the relationship between cancer, metabolism, sugar, insulin, body fat, and prostate cancer progression. He discusses the Warburg theory, which suggests that cancer may begin with dysfunctional mitochondrial metabolism, and compares it with the later focus on genetic causes of cancer. While he argues that the idea of “starving cancer” by eliminating sugar is too simplistic, he also emphasizes that metabolic health plays a real role in cancer risk and progression.The episode focuses heavily on prostate cancer, which Dr. Petteruti describes as unique compared with other cancers. He argues that conventional approaches often overlook the environment in which cancer develops, including excess body fat, high insulin, elevated blood sugar, inflammation, and poor metabolic health. He also discusses tests such as fasting insulin, hemoglobin A1c, and continuous glucose monitoring, as well as the importance of nutritional and behavioral change. The episode closes with a warning against extreme diets, oversimplified supplement advice, and one-size-fits-all cancer theories.Timestamps:(00:00) What Causes Cancer?(01:02 )The Warburg Theory(02:14) Genetics vs. Metabolism(04:22) Why “Starving Cancer” Is Too Simplistic(05:42) Body Fat, Insulin, and Prostate Cancer(08:30) Tests That May Help Assess Metabolic Health(10:47) Food, Weight Loss, and Cancer Risk(13:42) The Anti-Cancer Lifestyle(15:04) Toxins, Viruses, and Parasites(16:15) NAD, Mitochondria, and Supplement Caution(17:33) Growth Hormone, IGF-1, and Cancer Risk(19:12) Why Extreme Dieting Is Not the AnswerEnjoy the podcast? Subscribe and leave a 5-star review on your favorite platforms.Dr. Stephen Petteruti is a board-certified physician specializing in longevity-focused, integrative medicine. He works with men navigating prostate cancer, testosterone, and hormone health, aging, and performance using proactive, evidence-informed strategies grounded in real clinical practice. His approach prioritizes preserving function, strength, and quality of life while helping patients make clear, informed decisions beyond reactive, fear-driven care.Book: Fight Cancer Like a Man: https://tinyurl.com/FightLikeAManBookDr. Steve's email newsletter: https://drstephenpetteruti.substack.com/subscribePodcast show notes : https://www.intellectualmedicine.com/podcast-notesMember exclusive content: https://tinyurl.com/DrPetterutiMemberLearn more: https://www.drstephenpetteruti.com/ Learn more: https://www.intellectualmedicine.com/ Connect with Dr. Petteruti on:⁠Instagram: ⁠https://www.instagram.com/dr.stephenpetteruti/⁠ Facebook: ⁠https://www.facebook.com/dr.stephenpetteruti⁠ Disclaimer:The content presented in this video reflects the opinions and clinical experience of Dr. Stephen Petteruti and is intended for informational and educational purposes only. It is not medical advice and should not be used as a substitute for professional diagnosis, treatment, or guidance from your personal healthcare provider. Always consult your physician or qualified healthcare professional before making any changes to your health regimen or treatment plan.

More than just a game—Knicks overcoming odds in game 4 comeback is a parable of resilience; A one and done lifetime cholesterol fix via gene modification; Will cataract surgery interfere with benefits of light exposure? Do amounts of vitamin A in various supplements taken together court the risk of toxicity? Smartphones and social media create real harm for adolescents; Experts determine the exact right amount of sleep down to the minute—but is it overreach? 

What if resilience isn't about pushing harder, but about learning how to move forward with grace, courage, and joy when life doesn't go according to plan? In this powerful conversation, Dr. Mariza sits down with bestselling author, speaker, coach, and podcast host Amberly Lago to discuss resilience, overcoming adversity, and finding purpose through life's most difficult challenges. After surviving a devastating motorcycle accident that nearly took her life, enduring dozens of surgeries, and being diagnosed with Complex Regional Pain Syndrome (CRPS), Amberly faced years of chronic pain, uncertainty, and reinvention. Rather than allowing her circumstances to define her, she chose to build a life rooted in resilience, gratitude, faith, community, and purpose. Together, they explore the mindset shifts that help women move through difficult seasons, the role of gratitude in healing, why joy is a daily practice rather than a destination, and how small habits can create profound transformation over time. Whether you're navigating health challenges, career transitions, relationship struggles, or simply feeling stuck, this conversation offers practical tools and powerful encouragement to help you move forward with greater confidence and hope. AMBERLY LAGO Amberly Lago is a bestselling author, resilience coach, TEDx speaker, top-ranked podcast host, and motivational speaker. After surviving a catastrophic motorcycle accident and living with Complex Regional Pain Syndrome, she transformed her personal challenges into a mission to help others build resilience, find joy, and create meaningful lives despite adversity. She is the author of multiple books, including Joy Through the Journey and True Grit and Grace. IN THIS EPISODE How resilience is built through daily decisions and small actions Amberly's remarkable recovery journey after a life-changing accident Why gratitude can shift your mindset during difficult seasons The importance of acceptance when facing unexpected challenges How community helps accelerate growth and confidence Why joy is a strategy, not just an emotion The role of habits, discipline, and non-negotiables in long-term success How to move forward when life feels uncertain or overwhelming QUOTES “You can't be grateful and miserable at the same time.” “Resilience isn't about bouncing back. It's about moving forward.” “When you've got grit, there is no quit.” RESOURCES MENTIONED Order my newest book: The Perimenopause Revolution https://peri-revolution.com/ Use code DRMARIZA and get 10% off on your Womeness Order https://www.womaness.com/DRMARIZA Joy Through the Journey Book by Amberly Lago True Grit and Grace Book by Amberly Lago The Amberly Lago Show Amberly Lago Website Amberly Lago Facebook Amberly Lago Instagram Amberly Lago Youtube RELATED EPISODES  753: The Brain's Hidden Role in Chronic Pain, Migraines & Fatigue with Dr. Howard Schubiner 717: “I Don't Feel Like Myself Anymore”: The Mental & Emotional Reality of Perimenopause 741: Estrogen, Gut Health, Mitochondria, and Cardiovascular Health: What Changes In Perimenopause with Dr. Siobhan Mitchel 743: Why Your Heart Risk Changes in Menopause (And What You Can Do About It) with Dr. Jayne Morgan

Dr. Pamela Cipriano shares her journey from being an ICU nurse to a trailblazer in functional medicine. She discusses her personal experiences with Lyme disease, the importance of hydration, nutrition, and the impact of chronic illnesses. Dr. Cipriano emphasizes the need for a holistic approach to health, focusing on root causes and lifestyle changes, while also sharing insights on the effects of COVID and the importance of proper diet and hydration. In this conversation, Dr. Pamela Cipriano discusses the implications of vaccination, particularly in relation to health concerns and the effects of spike proteins. She emphasizes the importance of Vitamin B12 and mitochondrial function in overall health, while also addressing oxidative stress and innovative therapies for chronic conditions. The discussion extends to the future of Lyme disease treatment and the challenges in diagnosing and treating Bartonella, highlighting the need for proper education and awareness in managing tick-borne diseases.   For Audience Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now   Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!      Takeaways   ·       Dr. Cipriano transitioned from nursing to functional medicine to help patients achieve better health. ·       Her personal experience with her son's Lyme disease shaped her focus on chronic illnesses. ·       Chronic diseases often have triggers that can be identified and addressed. ·       Water intake is crucial for overall health and disease prevention. ·       Nutrition plays a significant role in managing inflammation and chronic diseases. ·       Avoiding processed foods and sugars is essential for maintaining health. ·       The quality of food, including meat and dairy, impacts health outcomes. ·       Functional medicine requires a thorough understanding of a patient's history and lifestyle. ·       COVID-19 has highlighted the importance of diet and hydration in recovery. ·       The healthcare system often prioritizes medication over holistic health solutions. Vaccination can lead to health problems in some individuals. ·       Spike proteins may persist and cause long-term health issues. ·       Vitamin B12 is crucial for nervous system health. ·       Mitochondria play a vital role in cellular function and energy production. ·       Oxidative stress accelerates aging and cellular damage. ·       IV therapies can significantly aid in recovery from chronic conditions. ·       Bartonella can mimic severe neurological disorders like ALS. ·       Proper testing is essential for diagnosing tick-borne diseases. ·       Education is critical for effective treatment of Lyme disease. ·       Innovative therapies are emerging for chronic health issues.       Chapters 00:00 Introduction to Dr. Pamela Cipriano 01:32 Journey into Functional Medicine 02:52 Personal Experience with Lyme Disease 04:55 Understanding Chronic Illnesses 06:57 The Importance of Water and Hydration 13:43 Nutrition and Anti-Inflammatory Foods 19:28 Insights on COVID and Long COVID 20:26 The Impact of Vaccination and Health Concerns 21:53 Understanding Spike Proteins and Their Effects 22:38 The Importance of Vitamin B12 23:54 Mitochondrial Function and Health 25:53 Oxidative Stress and Its Management 27:45 Innovative Therapies for Chronic Conditions 30:37 The Future of Lyme Disease Treatment 32:55 Bartonella: Diagnosis and Treatment Challenges 39:56 Navigating Tick-Borne Diseases   To learn more about Dr. Pamela Cipriano: Facebook: https://www.facebook.com/Dr.Pamela.Cipriano Instagram: https://www.instagram.com/practicehealthwellness YouTube: https://www.youtube.com/@dr.pamelacipriano1329 Website: https://www.thepracticeofhealthandwellness.com   Reach out to us at:    Website: https://gladdenlongevity.com/     Facebook: https://www.facebook.com/Gladdenlongevity/    Instagram: https://www.instagram.com/gladdenlongevity/?hl=en     LinkedIn: https://www.linkedin.com/company/gladdenlongevity    YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw    

Do you feel exhausted but can't seem to wind down? That wired-but-tired feeling so many women experience in midlife has a name, and a cause most doctors never address. In this episode of The Art of Living Well Podcast®, Marnie and Stephanie are joined by Dr. Scott Sherr, a board-certified internal medicine physician and expert in health optimization, to explore the connection between chronic stress, hormone changes, and mitochondrial dysfunction. Dr. Scott introduces the concept of the "sympathetic spiral of doom" — the cycle of stress, poor sleep, and cellular energy breakdown that keeps so many women stuck, and shares practical, science-backed ways to break it. The conversation covers methylene blue (what it is, how it works, and who should use it), GABA and nervous system support, and hyperbaric oxygen therapy. Dr. Scott also explains why only 6% of US adults have optimally functioning mitochondria, and what the other 94% can do about it. Key Takeaways: Chronic stress and hormone fluctuations directly impair mitochondrial function Estrogen is a critical mitochondrial optimizer, losing it in perimenopause has real cellular consequences Only 6% of US adults are metabolically healthy; symptoms of the rest range from brain fog to poor sleep to slow recovery Methylene blue supports mitochondrial energy production and works as a bridge while you optimize your health more broadly If a GABA supplement works for you, that's a warning sign worth paying attention to Down-regulating the nervous system too fast, without mitochondrial support, can cause a crash Hyperbaric oxygen therapy is most effective once you have a foundational health plan in place Sleep is one of the most powerful levers for mitochondrial health 00:00 – Introduction and Dr. Scott's background 04:13 – Why midlife women's bodies stop responding the way they used to 07:32 – Progesterone, GABA, and sleep disruption 09:04 – What mitochondria actually do and why they matter 13:16 – The 6% metabolic health statistic 17:00 – The sympathetic spiral of doom, explained 21:01 – Cortisol: misunderstood and mismanaged 29:32 – What methylene blue is and how to use it 33:55 – Who should not take methylene blue 38:33 – Performance, travel, and targeted use 47:17 – GABA support and down-regulating the nervous system 55:18 – Hyperbaric oxygen therapy: benefits, timing, and protocols 01:00:52 – One action to take today 01:03:09 – Where to find Dr. Scott and his products Guest Links: Dr. Scott Sherr: drscottsherr.com Troscriptions: troscriptions.com Use code LIVINGWELL for 10% off Products mentioned: Just Blue, Blue Cannatine, Tro Calm, Tro Zzz This episode is brought to you by Good Health Saunas. Visit goodhealthsaunas.com and mention The Art of Living Well Podcast® for exclusive pricing. Ready for a Reset, On Your Own Time? If you've been feeling sluggish, bloated, inflamed, foggy, or just not like yourself, our Vitality Reboot Anytime is a simple way to give your body the reset it's been craving. This is our do-it-yourself version of The Art of Living Well Podcast® community detox, designed so you can move through the program whenever it works best for you. You'll receive everything you need to support your body with nourishing foods, targeted detox support, and simple daily practices that help you feel lighter, clearer, and more energized. Subscribe to our Substack for wellness tips, episode updates, and your free Midlife Travel Resilience Checklist: theartoflivingwell.substack.com Follow us: Instagram: @theartofliving_well YouTube: @theartoflivingwellpodcast LinkedIn: The Art of Living Well Podcast TikTok: @theartoflivingwel Spotify and Apple Podcasts Connect with your hosts: theartoflivingwell.us/about-us

Every fibroblast inside your dermis right now is asking 200 to 2,000 mitochondria to power its work in real time, and those mitochondria are descendants of a free-living bacterium swallowed by a larger cell 2 billion years ago. As you age, those mitochondria run slower and your cells build fewer of them to replace the ones that fail.In this solo episode, Young Goose co-founder Amitay Eshel breaks down the two sides of mitochondrial decline that drive skin aging and explains why the science-led skincare category has spent the last decades addressing only one of them.The first side of skin aging is where most skincare brands have built their products around. The other side is the one almost no skincare on the market is formulating for, and it is where the next chapter of skin longevity is being written.If you have outgrown the antioxidant-and-peptide era of skincare and want to understand what is actually happening underneath your skin as it ages, this episode is for you.What's Discussed:(01:35) The 2-billion-year-old contract inside every skin cell that is now fraying.(04:10) Why skin is one of the most mitochondria-dense organs in your body.(08:20) The 2012 paper that showed NAD drops by half between 35 and 70.(13:15) How a refugee fired in 1933 figured out the chemistry your cream still runs on.(16:30) The second half of the decline almost no skincare addresses.(19:45) The master regulator that decides whether your cells can hire.(24:00) The two columns of mitochondrial biology and why most brands only work in one.(32:10) Why this is a ten-year strategy, not a two-week one.Resources Mentioned:Download the Cellular Energy Protocol: https://www.younggoose.com/pages/the-mitochondrial-skin-stackAge-Associated Changes in Oxidative Stress and NAD+ Study: journals.plos.org/plosone/article/FASEB study on how methylene blue delays cellular senescence cells: faseb.onlinelibrary.wiley.com/doi/Find more from Young Goose:Use code PODCAST10 to get 10% OFF your first purchase, and if you're a returning customer use the code PODCAST5 to get 5% OFF at younggoose.comInstagram: @young_goose_skincare

What if your chronic pain, migraines, anxiety, fatigue, IBS, or other persistent symptoms aren't permanent at all? In this fascinating conversation, Dr. Mariza sits down with Dr. Howard Schubiner, physician, researcher, and leading expert in neuroplastic symptoms, to explore a groundbreaking approach that is helping people reverse chronic pain and other conditions long considered lifelong and irreversible. Dr. Schubiner explains how the brain creates pain as a protective danger signal, why emotional injuries can activate the same neural pathways as physical injuries, and how unresolved trauma, chronic stress, adverse childhood experiences, and self-silencing can contribute to chronic symptoms years or even decades later. Together, they discuss the growing body of research around neuroplastic pain, the connection between emotions and physical symptoms, and why many people continue suffering despite normal scans, medications, and conventional treatments. Dr. Mariza also shares her own experience with chronic migraines, leading to a powerful live demonstration of how pain reprocessing techniques can begin shifting the brain's expectations and neural patterns in real time. This conversation offers hope for anyone who has been told they simply need to manage their symptoms for the rest of their life. HOWARD SCHUBINER Dr. Howard Schubiner is a physician, researcher, educator, and one of the leading voices in the field of neuroplastic symptoms. He is the author of Unlearn Your Pain and has spent decades helping patients recover from chronic pain, migraines, fibromyalgia, IBS, anxiety, chronic fatigue, and other conditions through evidence-based approaches rooted in neuroscience, emotional processing, and neuroplasticity. IN THIS EPISODE What neuroplastic symptoms are and why they are often misunderstood How childhood experiences, trauma, and chronic stress can contribute to chronic pain Why migraines, IBS, fibromyalgia, anxiety, and fatigue may share similar brain-based mechanisms The powerful connection between emotions and physical symptoms How pain reprocessing therapy helps retrain the brain's danger signals Why self-silencing and people-pleasing often show up in women with chronic symptoms The role of emotional awareness and expression in healing A live demonstration of changing neural pathways through visualization and safety signals QUOTES“Pain can be a message that our brain sends.” “Emotional injury causes the same parts of the brain to light up as physical injury.” “Chronic pain is not necessarily a life sentence.” RESOURCES MENTIONED Use code ENERGIZED and get 30% off on your first BATCH order http://hellobatch.com/ENERGIZED Get your copy of Dr. Howard Schubiner Newest Book now https://www.amazon.com/Unlearn-Your-Pain-Recovering-Depression/ Unlearn Your Pain Website The Association for the Treatment of Neuroplastic Symptoms (ATNS) Howard Schubiner Instagram Howard Schubiner Facebook RELATED EPISODES  751: Bloating, Brain Fog & Hormone Chaos? Your Gut May Be the Root Cause with Dr. Cassie Smith 743: Why Your Heart Risk Changes in Menopause (And What You Can Do About It) with Dr. Jayne Morgan 717: “I Don't Feel Like Myself Anymore”: The Mental & Emotional Reality of Perimenopause 741: Estrogen, Gut Health, Mitochondria, and Cardiovascular Health: What Changes In Perimenopause with Dr. Siobhan Mitchel

This week I interviewed Dr. Aleksandra Gajer, MD—a board-certified physician, metabolic health expert, and founder of The Gajer Practice. Her clinic is dedicated to a root-cause focused approach, helping patients reclaim energy, balance hormones, and optimize whole-body performance. We discussed how she uses peptides to optimize metabolic health along with:- Important Labs to look for - The problem with too much restriction-  Why weight gain in midlife isn't your faultand her one tip to get your body back to what it once was!Connect with Dr. Gajer:  https://thegajerpractice.com/-------------Click to book a FREE 15 minute consult with Brian:https://calendly.com/bdgryn/15min------------Interested in Upgrading your Mitochondria, Improving Energy and Sleep! Check out Troscriptions: https://bit.ly/4ik5kK5Use Discount Code for 10% OFF: EATCLEAN----Watch Get Lean Eat Clean podcast video episodes on YouTube!YouTube.com/@briangryn3680----B.rad Whey Protein Isolate Superfuel:The Best Protein on The Planet! Available in Two Delicious Flavors: Vanilla Bean and Cocoa BeanUse Coupon Code glec10off for 10% off your order!https://a.co/d/731gssV----My favorite health bars with clean ingredients!https://www.eatprima.com/BRIAN6816310% OFF with this link!

EWOT for Stroke Recovery: The Affordable Alternative to Hyperbaric Oxygen Therapy Brad Pitzele did not set out to become an oxygen therapy equipment maker. He set out to survive. After years of battling significant health challenges, conventional medicine had given him answers that kept failing him. He tried around 200 treatments. Some helped. Many did not. Then he found EWOT Exercise With Oxygen Therapy, and something finally shifted. Brad’s journey is not the same as a stroke. But what he discovered about oxygen, inflammation, and cellular energy maps directly onto one of the most stubborn obstacles stroke survivors face: the feeling that the brain has gone offline, that the body is running on empty, and that the path back is either impossibly expensive or simply does not exist. In Episode 407 of the Recovery After Stroke podcast, Brad shares what EWOT is, why it works, and why he now makes affordable EWOT systems through his company, One Thousand Roads, specifically so survivors do not have to remortgage their homes to access oxygen-driven recovery. What Is EWOT? EWOT stands for Exercise With Oxygen Therapy. The concept is straightforward: you breathe high-concentration oxygen through a mask while exercising even lightly, and that combination pushes oxygen into parts of the body that normal breathing cannot reliably reach. Most people assume oxygen therapy means a hyperbaric chamber: a pressurized tube, a clinic, a course of treatments costing tens of thousands of dollars. Hyperbaric oxygen therapy (HBOT) is effective. Brad describes it as “a heroic treatment.” But it is also inaccessible for most survivors, financially and logistically. EWOT operates on a related principle without the chamber. The key mechanism is not about oxygenating red blood cells; they are already carrying close to their maximum load under normal breathing. The target is the blood plasma. Plasma does not carry oxygen efficiently under resting conditions, but during exercise, even light exercise, blood pressure and circulation increase enough to force dissolved oxygen into the plasma. That plasma can then reach the micro-capillaries, the tiny vessels that feed tissues deep in the body, including areas of the brain that become inflamed and oxygen-starved after a stroke. The Post-Stroke Energy Problem One of the most commonly reported and least-explained symptoms after stroke is fatigue that does not go away, no matter how much a survivor rests. Most survivors are told that is just part of it. Brad’s framework centres on mitochondrial dysfunction. Mitochondria are the energy-producing structures inside cells. After stroke, the cells in and around the affected area are often not dead; they are in a kind of low-power state. Brad describes it as a “brownout”: the lights are on, but dimly. The mitochondria are not producing energy at full capacity, and one significant reason for that is insufficient oxygen supply to the tissue. “The cells that are offline after a stroke are not all dead. Some of them are just starving. Oxygen is part of what feeds them back.” — Brad Pitzele, Episode 407 When EWOT increases plasma oxygen during exercise, it can reach those inflamed, under-oxygenated micro-capillaries that larger vessels cannot access. The result, for some survivors, is a gradual improvement in energy, cognition, and physical capacity, not because the therapy is miraculous, but because it addresses a specific physiological deficit that conventional post-stroke care often does not target. EWOT vs. Hyperbaric: What’s the Real Difference? The honest answer is that EWOT and hyperbaric oxygen therapy are not equivalent. HBOT delivers oxygen under pressure, which drives it into tissue more forcefully. For certain conditions, particularly in acute or severe cases, hyperbaric oxygen has a stronger evidence base.  But for many stroke survivors in the subacute or chronic phase of recovery, access is the defining variable, not theoretical ceiling. A home-based hyperbaric unit costs $50,000 to $75,000. A clinical course can run to $60,000 or more. EWOT systems are available for under $2,000.  The question Brad puts to survivors is not “which is better in a lab?” It is: “Which one can you actually do, consistently, at home, over the months and years that brain recovery requires?” Consistency matters more than peak intensity in long-term neurological recovery.  Starting EWOT With Deficits EWOT does not require running on a treadmill. The exercise component can be a stationary bike, a recumbent bike, or simple seated leg movements with one limb strapped in. The goal is to raise circulation enough to push oxygen into the plasma, not to hit a cardiovascular fitness target. For survivors exploring this option, Brad’s team has built a specific resource at onethousandroads.com/stroke-recovery with a listener discount of $100 to $500, depending on the package. There is also a broader introduction to EWOT at onethousandroads.com/pages/exercise-with-oxygen-therapy. Recovery Is Possible — And It Does Not Have to Be Expensive If this episode resonated with you or if you want to explore more conversations about recovery options that do not require a second mortgage, Bill’s book, The Unexpected Way That A Stroke Became The Best Thing That Happened, is available at recoveryafterstroke.com/book. And if the Recovery After Stroke podcast has been useful to you, you can support it financially at patreon.com/recoveryafterstroke. Every contribution helps keep the show going and these conversations accessible to survivors around the world. This blog is for informational purposes only and does not constitute medical advice. Please consult your doctor before making any changes to your health or recovery plan. EWOT for Stroke Recovery: The Affordable Alternative to Hyperbaric Oxygen Therapy Why pay $60,000 for hyperbaric oxygen? EWOT brings oxygen therapy into your living room — and could help the brain cells that are only offline. One Thousands Roads Exercise With Oxygen Therapy (EWOT) YouTube Channel Highlights: 00:00 Introduction and Background 05:37 Challenges in Stroke Recovery and Treatment Options 13:45 Understanding Oxygen Therapy and Its Mechanism 15:51 Oxygen Toxicity Explained 19:24 The Importance of Oxygenating Blood Plasma 24:53 Oxygen and Mitochondrial Function 31:16 Adapting Exercise for Stroke Survivors 38:27 Cost and Accessibility of Oxygen Therapy Devices Transcript: Introduction – EWOT for Stroke Recovery Brad Pitzele (00:00) like many of your listeners, when you have a medical issue that isn’t treated by traditional medicine and you’re desperate to get your life back, you’ll try just about anything. You, the lens it goes through is like, Well, how bad can this hurt me? BIll Gasiamis (00:15) Welcome back to Recovery After Stroke. I’m your host, Bill Gassiamas. Today’s guest is Brad Pitzele, founder of 1000 Roads, who overcame significant health challenges of his own and along the way discovered the science behind exercise with oxygen therapy. In this conversation, we get into how increasing oxygen saturation in the blood, specifically in the blood plasma, can help reach the inflamed microcapillaries. That are blocking oxygen delivery to cells in the recovering brain. We talk about mitochondrial dysfunction, post-stroke fatigue, and why Ewatt is worth understanding as an accessible alternative to hyperbaric oxygen therapy. Before we get into it, if you’ve found value in this podcast and want to support it financially, you can do that at patreon.com/slash recovery after stroke. And if you haven’t yet read my book, The Unexpected Way That a Stroke Became the Best Thing That Happened, it is available at recovery after stroke dot com slash book. Here’s my conversation with Brad. BIll Gasiamis (01:19) Brad Pitsley, welcome to the podcast. Brad Pitzele (01:22) Thank you so much. BIll Gasiamis (01:24) Thanks for reaching out and ⁓ connecting with me to educate me on another thing that I can bring to stroke survivors that could potentially help them in the rehabilitation side of their brain. The the thumbnail that people found on YouTube is probably gonna have E W O T on it somewhere. E what. And it sounds something like something out of that ⁓ space war out of out of what is it? Brad Pitzele (01:53) Star Wars. Star Wars. BIll Gasiamis (01:54) Star Wars. Like the Ewok, right? And it doesn’t really mean anything to me. But before we descri tell people what Ewok is, ⁓ tell me a little bit about your background, the work that you do and how it is you came to be on the podcast today is for s for for the specific discussion that we’re gonna have. Brad Pitzele (01:58) Yep. Sure. ⁓ yeah, so I ⁓ I I’m an e recovering engineer. I like to joke. I spent my first decade of my life engineering. later on in life, I left engineering and went into different pursuits and I became chronically ill, had a variety of medical issues, ⁓ cancer, autoimmunity, and eventually Lyme disease. And I was in really bad shape. And a doctor recommended I look into either hyperbaric oxygen or this exercise with oxygen therapy, EWAT, that almost no one had heard of, and I’d never heard of it. ⁓ I I I had tried like everything to get better at this point. I was many years in special diets, ⁓ all sorts of supplements and ⁓ all sorts of modalities and things. And nothing really worked. There was nothing in a matter of fact, some of the medications I took actually gave me cancer. So it kind of forced me on this road to try something different. ⁓ and eventually I found my way back to health through exercise with oxygen when so many things weren’t working. ⁓ and actually later paired that with ⁓ red light therapy. ⁓ and along the way I started because I’m an engineer and I’m inquisitive, I like It was Lyme disease is kind of a do-it-yourself disease. ⁓ so I started digging in and pouring into research, not just on Lyme disease, but autoimmunity, ⁓ chronic illness, ⁓ trying to figure out what the heck was going on with me. And so ⁓ what I found about exercise oxygen therapy along the way was really fascinating to me. and about a year into using it, I went back to that same doctor and he was kind of shocked. At my turnaround, and he was like, What did you use? Did you do oxygen? And I said, I did. And he was like, Who’d you buy it from? I want to tell my patients about it. And I said, I didn’t buy it, Doc. I actually ended up making my own. And he was kind of surprised by that for obvious reasons. And then he said, Well, gosh, would you consider making it for my patient? And so, my patients, and so that’s how we got into this business back in two thousand eighteen. We launched one thousand roads to kinda make exercise with oxygen therapy accessible to people who are dealing with chronic health conditions. BIll Gasiamis (04:39) Okay. And it stems from science, right? There’s scientific data that backs up this exercise with oxygen therapy. Before you go into that a little bit, we don’t have to go deep into it, but we can just ⁓ chat about it. ⁓ when I talk to stroke survivors, they get stuck always with what should I do? What should I do? What should I do? They want the The blue pill, take that one, everything gets fixed. I mean, stroke is not like that, right? And it’s and it’s stroke is also a you’re on your own kind of thing. Because once you get out of the acute phase, once you get sent home, the ⁓ follow up and the medical fraternity doesn’t have a system to kind of say to you, we can’t help you. Speak to that guy. ⁓ that guy might not be able to help you, but but there’s a guy over there. Brad Pitzele (05:09) Yeah. Challenges in Stroke Recovery and Treatment Options BIll Gasiamis (05:33) Like there’s none of that. And stroke survivors need podcasts. They need ⁓ people selling all sorts of crazy stuff that they will almost try almost all the time. They’ll try everything. And then they’ll pick and finally stumble into one that helps and gets them a result. But before we talk about all of that, what I want to do is also go back to what you said about ⁓ a year later, you went to your doctor, he was stunned at the result. We can’t put that down just to eat what? We can’t put that down just to exercise with oxygen therapy. Give me the brief steps on the other things that you also attended to because people miss that. Brad Pitzele (06:15) Yes. Yeah. I well, here’s what I’ll tell you. I started I started to get arthritis in my hands in like 2010 or eleven. and then I started taking traditional drugs for it. And one of the side effects of the drugs is higher risk of cancer and specifically melanoma, which I developed in two thousand thirteen, I wanna say, maybe two thousand fourteen. And that kicked me off the traditional medical path. ⁓ to your point, you don’t you don’t in the stroke recovery, there’s not a traditional path. There it was a traditional path, but it was clear that it was a you know it was a choice between cancer and autoimmunity, and neither one seemed great to me. ⁓ from there I tried so many things, Bill. I did s I actually made a list recently and looked at it because I had it like just off the top of my head, I came up with 200 different things I did try. We’re talking special diets. Eating all sorts of weird, strange things, all sorts of supplements, antibiotics, because it’s Lyme disease, herbal protocols, ⁓ ozone treatments, sa various different types of saunas, ozone sauna, infrared sauna, ⁓ heat steam saunas, ⁓ colonics, coffee enemas, ⁓ weird stuff, you know, you’d never think you’d do. I mean BIll Gasiamis (07:39) You are committed Brad Pitzele (07:42) ‘Cause like many of your listeners, when you have a medical issue that isn’t treated by traditional medicine and you’re desperate to get your life back, you will you’ll try just about anything. You the the lens it goes through is like, Well, how bad can this hurt me? Like like ’cause I know where I’m going right now. For me at least it was a I was just like this gradual step down. It was like I knew like I I couldn’t do this. I had a young family. so, you know, that doctor, I remember him saying, like, look, Brad, we’re trying all these things, we’re gonna get you on thyroid medications and get that right, and we’re gonna do this. ⁓ there on that list of 200, there were about eight things that gave me any kind of benefit that I could identify. ⁓ But I remember he’s like, Brad, we’re gonna take out the big dog. We’re gonna do this ozone treatment. And it’s a special kind where we remove the blood from your body, we inject ozone, put it through UV light, and put it back into your blood. And this helps everyone. Like if nothing else works, this helps, but it’s really expensive. So we’re saving it, kind of. So he he did it. He’s like, do a course of three of them. And he’s like, You might feel bad after it the next day because it kills a bunch of stuff and might you might feel toxic. Or you might feel better. We’re not sure. And give it a few days. And like I did all three of them, I never noticed a difference. And it was ⁓ the most depressing, scary part was like going through that. So when he said go do oxygen, I was like, Okay, like I’ve done everything else. I’m just gonna check the box so the doctor knows that’s not gonna work, so we can go try to find something else. ⁓ And I didn’t believe it was gonna work. I I you know, I didn’t jump on the the bandwagon gung-ho. I was, you know, kind of kicking and screaming. And that was part of the reason I built my own, is because at the time they were so expensive and the they were five to twenty-five thousand dollars. And I was like, I just can’t spend, you know, ten thousand dollars on an experiment. I just can’t do that. ⁓ And he also suggested maybe hyperbaric and that was like fifty or seventy-five thousand dollars. And I was like, geez, if I knew this was the the blue pill, as you said it, if I knew this was the blue pill, I’d go mortgage the house and I’d go do it because like then I could work full and I could do all the things, I could be present for the family, but ⁓ I couldn’t. BIll Gasiamis (10:05) And and and you know what? And it’s not, and and the reason it’s not for a lot of people is because you need to have penumbras the brain from a stroke survivor perspective that are recoverable and that you can bring back to life that are offline, not dead by ⁓ cell death because of the stroke. And there’s no diagnostic process in the majority of the people I’ve spoken to, you can’t diagnose somebody and then work out whether they’re a candidate, and that really Brad Pitzele (10:20) Yeah. Right. BIll Gasiamis (10:33) Pisses me off to somebody gonna have to spend 50 grand to find out if they’re gonna get a result, right? The s the guys that who I’ve interviewed about hyperbaric oxygen therapy, ⁓ Viv clinics, ⁓ those guys will do a thorough diagnostic beforehand to determine whether somebody is a candidate. And whatever that costs, even if it’s five grand, I don’t know what it does cost, but even if it’s five grand, at least you can go, you’re not a candidate, don’t spend any more money. Brad Pitzele (10:38) Yeah. Right. higher yes, you have a higher level of certainty before you spend the money. BIll Gasiamis (11:04) Yeah. And if you do do it, you’re doing it for the other ⁓ non-brain related benefits that you’re gonna get from hyperbaric oxygen therapy. And that’s totally up to you. But it’s not the thing to supposedly fix the arm or the leg that doesn’t work, or to ⁓ repair the damaged cells in your brain. So that part really frustrates me. And if I’m gonna spend that much money, then there’s the opportunity cost as well. It’s like Brad Pitzele (11:33) Yes. BIll Gasiamis (11:34) Now I can’t spend that somewhere else. Brad Pitzele (11:36) Exactly. That was me too. It was like you you knew you had and I was like, man, if I spend this kind of money on it and it doesn’t work, like nothing’s worked for the last, I don’t know, almost ten years at this point. Like how many of these shots do I have in the cannon, right? Like you you know, now I’m I’m depleted and I’m still sick. And that’s even i and you know this, when you’ve got a chronic health condition, sometimes the psych psychology of it all is just as hard as the condition. And If you’re like, wow, now I don’t have money. I feel trapped. There’s nothing I can try. Then hope starts to dwindle. And I say like hope is is like the most potent weapon in recovering from a chronic health condition. It’s a double-edged sword because like you’re s afraid to get hope up because you’ve been let down. But it’s also the thing you need. You ha like when when you start losing hope, and I and I’ve been at that point, it just gets incredibly dark. ⁓ and incredibly scary. so I I think that was part of it. I just wouldn’t allow it. It was the financial part. I you’re right. You only have so many shots out of the bow. But it was also like if it doesn’t work and I am depleted financially you know, I don’t like that that brings me to a a level of hopelessness I I’m not sure I can confront. BIll Gasiamis (12:53) Yeah. And then in order to get back up, you’re getting back up, you’re financially depleted, you’re energetically depleted, your health is depleted. And it’s like, my God, that is a that is like the lowest place that you can find yourself and to get back up is a lot harder. And yet people have still done that, but I know the task is harder. I’ve been in a similar sort of situation. Brad Pitzele (13:12) Yeah. We all love we all love reading that inspirational story. No one wants to live it if they can avoid it, I’ll tell you. Understanding Oxygen Therapy and Its Mechanism BIll Gasiamis (13:23) Avoid it. Yeah, a hundred percent. ⁓ so so you’ve tried all this stuff, you’re unwell, and then somebody says to you, try oxygen. Now, what I imagine when I hear oxygen is get a can from the local gas supplier, ⁓ pop pot in a tube, put it on the back of your chair, wheelchair. You know, I’ve seen a lot of older guys who have got it, and then they’ve got oxygen attached to their face and they’re breathing in oxygen. What specifically did your doctor tell you to get and if you didn’t get what he suggested, like w what did it look like for you? Brad Pitzele (14:00) Yeah, so the challenge with bottled oxygen is number one, it’s almost impossible to get. number two is when you exercise, you can take in a massive amount of oxygen, and that’s part of what makes the the therapy really cool. So y you and I sitting here, maybe we’re taking in three liters of oxygen a minute, okay? ⁓ three liters of air a minute, maybe something like that. ⁓ When you’re exercising, you can easily take in 50 or 60 liters. So it’s a massive multiplier. So you need something that’s going to give you a large amount of oxygen. Now, there’s two ways you can get oxygen in your home. One is that bottle you mentioned, and then you’re always refilling it, and you can imagine lugging one of those things around. ⁓ the other way is there’s a device called an oxygen concentrator, and all you do is you plug it into the wall. And it turns the it purifies the oxygen in the room. So, you know, at sea level, the oxygen in the room has 21% oxygen and it can purify it to 93%. Now, the challenge with these devices is they put out either five or ten liters of oxygen in a minute. So not enough to exercise with. If you were to try to exercise with it, you would also be sucking in this air at 21% and diluting it. ⁓ and so what you do is you take this device and you fill a large reservoir, it’s about a thousand liters, ⁓ and you fill it up. using this device and then you hook up a hose with a mask on it and then you breathe through the mask while you do a fifteen minute exercise session. BIll Gasiamis (15:41) Okay. A reservoir, ⁓ water tank. Oxygen Toxicity Explained Brad Pitzele (15:45) It well it it’s like it looks like a big pillow. So it’s like six you know, two meters by two meters, sort of ⁓ big pillow, six feet by six feet for us still on Imperial. And you fill it up so a thousand liters and it’s you know it’s it’s thin film and so it’s not a a rigid body of something, and then yeah, it’s a bag. BIll Gasiamis (16:06) It’s a bag. Like a bagpipe, a massive bagpipe. Brad Pitzele (16:10) There you go. BIll Gasiamis (16:12) Okay. Okay. W I’m sure there’s an image of that, right? We’ll put it on the screen. People can see it while we’re talking about it, trying to work out what it is. Okay. So this thing is something that you accessed and you used specifically for yourself, how many years ago? Brad Pitzele (16:16) Yeah. Yeah. I’ve s I’ve been using it for a decade straight now. BIll Gasiamis (16:33) Okay. This stuff’s been around for about a decade. This Brad Pitzele (16:37) It’s well, the the research on it goes back to the nineteen sixties and seventies. This it’s really fascinating. actually some of the early research goes back to the turn of the ⁓ twentieth century, the nineteen hundreds. So in the early nineteen hundreds, a gentleman named Otto Warburg won a Nobel Prize for proving that he could turn any cancer or any regular cell into a cancerous cell by depriving it of oxygen. ⁓ and so there’s this really well-established linkage between oxygen and cancer. Even today, a ton of research on that. So in the 1960s and 70s, there was a a German physicist and prolific inventor named Manfred von Arden. Now, and he started to want to do research on Otto’s work, and he he actually started doing research on exercising with oxygen as an anti-cancer protocol. And some of the research he found was really fascinating. what without getting overly technical, basically it our circulatory system, obviously, this is really relevant to stroke, ⁓ people deal in strokes, is as you get down into the the end runs of your circulatory system, there’s capillaries and they’re like thinner than a human hair. And this is where your nutrients and your oxygen are actually exchanged with the cell. And what he found is as we age naturally this inflammation builds up on the lining of our capillaries. And it actually causes the capillaries to swell shut so that now none of your red blood cells can get by. Now, I mean, this is how exquisite our body is designed. ⁓ our capillaries are actually thinner than a red blood cell. So under the most healthy of conditions. A red blood cell actually needs to fold up like a taco to get into our capillaries and deliver that oxygen in the last mile of our circulatory system. So any swelling in that capillary can cause a blockage. And now all the cells downstream are not getting oxygen and in a sufficient quantity. And so they kind of go into what they what he kind of referred to as like a brownout, right? Like it’s a low energy state. They’re doing anaerobic respiration to get some energy. Maybe some of the smaller red blood cells might squeak by here and there and give a little bit, but they’re not getting the full oxygen they need. And what he found is by doing this procedure, just a few times he had very elderly people with very inflamed ⁓ capillaries. He was able to re-establish normal blood flow. And the reason is is oxygen is incredibly anti-inflammatory. ⁓ and a lot of research on that we can go into a little bit later. The Importance of Oxygenating Blood Plasma So, number one, it causes this anti-inflammatory reaction inside these inflamed capillaries to reopen them. But it also does something really amazing that he discovered is when you’re doing this procedure, ⁓ it causes the oxygen to not just attach to our red blood cells like it always does, but it also saturates our blood plasma, which is this clearish liquid that our red blood cells ride on. And Our blood plasma is a thousand times thinner than a red blood cell. So if you imagine these blockages, red blood cells are not getting through, but obviously the blood plasma can get through as long as it’s like as thin as water. So as long as there’s any opening there, and it can immediately deliver oxygen downstream, both to cause an anti-inflammatory impact in the capillaries, but also to all those cells that are starving. And so you can obviously, as we’re talking through this, you can kind of see how this fits folks who are dealing with various different strokes ⁓ and how that can help them as well. BIll Gasiamis (20:32) Yeah. Okay. I d before we spoke I did a little bit of research and found ⁓ as well that there’s some there’s a lot of relevant data with regards to oxygen and ⁓ increasing the oxygenation in the blood. you so tell me a little bit about oxygen. I I don’t understand exactly what that is. I’ve heard of people becoming ill. Because of too much oxygen, ⁓ ill because of not enough oxygen. So what is what what is becoming ill of too much oxygen and why is ninety nine percent saturation not that? Brad Pitzele (21:18) Yeah, yeah. ⁓ good question. So oxygen toxicity can occur if you get too much oxygen under certain circumstances. So if you’re in a hyperbaric chamber too long, it can cause oxygen toxicity. And basically that’s when oxygen gets trapped in your bloodstream and it can’t get out. and You can actually get it without hyperbaric. So hyperbaric is oxygen under pressure. You can get it at normal barracks. So if you were just sitting on the couch breathing oxygen, you could eventually get oxygen toxicity. Now, it would take over twenty-four hours. So if you were breathing just pure oxygen, no exercise, sitting on your couch for 24 plus hours, it starts to get into the risky zone. When you’re doing exercise with oxygen, that’s actually one of the cool things about it that because of the synergies of exercise and oxygen, it’s impossible to get oxygen toxicity for two reasons. one is that reservoir is only a thousand liters. it’s not a high enough dose that you could get a oxygen toxicity. It is a massive dose, it’s about the same amount of oxygen you take in in a day, and you can take it in in 15 minutes, but it’s not more than. And the second reason, even if we could make our reservoir 10x, 100x, and you could exercise nonstop, you still couldn’t get oxygen toxicity because when you’re exercising, your body produces a massive amount of carbon dioxide gas. And that goes into our bloodstream and it increases pressure in our circulatory system. And that actually forces the oxygen out of the circulatory system and into the cells. So it works as a protectant as well from oxygen toxicity. So that’s oxygen toxicity. It’s a real risk. ⁓ Most of the time it’s a very controllable risk. You know, if you’re doing hyperbaric, they’re gonna keep you in there for so long so that you’re not gonna be at risk generally. ⁓ if you’re assigned to do oxygen while you’re stationary at home, they have protocols to make sure you’re not doing it, you know, twenty-eight hours nonstop sort of thing. ⁓ or they have you wear a cannula where where you’re also taking in air and it’s diluting it. ⁓ and in exercised oxygen therapy, it’s not really possible because of the massive amount of carbon dioxide. ⁓ now, not enough oxygen. So if you if you want to measure your oxygen in your blood, the way they normally do it is a device called the pulse oximeter. You can get one for 20 bucks off Amazon. What it does is it looks at how much how many of your red blood cells are saturated with oxygen. And what you’re gonna find in most folks. Is it’s close to a hundred percent. It’s ninety-eight percent, it’s ninety-six percent, ninety-seven percent. ⁓ there’s not a lot of room in our blood for more oxygen. So that’s why it’s important that ewak can actually oxygenate our blood plasma. The same with hyperbaric does the exact same thing, it oxygenates our blood plasma. So BIll Gasiamis (24:26) Okay. I think before you go on, that’s the key ingredient. It’s oxygenating the plasma as well. Where where previously you’ve got let’s say ninety seven, ninety eight percent saturation of your red blood cells. What we’re doing is adding that little bit of extra oxygen into the space where the plasma is. That’s kind of the key difference. Brad Pitzele (24:36) Yes. And there’s two reasons why it’s important. so normally, just for comparison, you and I sitting here, maybe 2% of all the oxygen in our blood is in our plasma, so it’s not very much. ⁓ but under these conditions of IWAT and hyperbaric, we can saturate that blood plasma. And it’s important for two reasons. One, obviously, it increases the oxygen carrying capacity of the blood, but that’s the more minor one. The more major one is that the blood plasma can get into let’s just say the nooks and crannies, smaller spaces in our body where inflammation is blocking off access of red blood cells to downstream cells. And so it can deliver a dose of oxygen where it normally is not able to get. BIll Gasiamis (25:40) You you’ve spent a lot of time on this topic by the sound of things. ⁓ and that’s really awesome. So before we talk about how to actually use a device, how to get a device, how to how to behave while you’re using a device, I wanna understand like how Oxygen and Mitochondrial Function Brad Pitzele (25:52) Yeah. BIll Gasiamis (26:02) How you notice the difference in yourself? Because a lot of people ask me what I did in my own stroke recovery. And Brad’s experience is going to be different from the stroke survivor’s experience. My experience was ⁓ I’ve got nothing from the doctors other than let’s monitor your bleed, let’s give you brain surgery. I mean, that’s not nothing. That’s amazing. Like I’m very Brad Pitzele (26:05) Yeah. Yes. BIll Gasiamis (26:31) Grateful for all of that. That removed the the blood vessel that was leaking that was going to potentially kill me. ⁓ so the immediate risk was gone. And then what what I mean I I got nothing is the specialists did their specialty and then I got nothing because they don’t do nutrition, they don’t do exercise, they don’t do meditation, they do brain surgery. And it’s really important for stroke survivors to understand that when you go to a doctor, a neurologist, whoever. Brad Pitzele (26:55) Yeah. BIll Gasiamis (27:00) They do a specific thing, and once they’ve done it, they can’t do anything else. And you need to get over the fact that you ⁓ might feel disappointment at the at that I don’t know where to go next, and they don’t know where to send you. Okay, they’re not trained and they cannot legally send you elsewhere. That’s why you’re kind of on your own. So I did meditation, I did nutrition, I did all this kind of stuff and Brad Pitzele (27:16) Yeah. BIll Gasiamis (27:27) Somebody who’s interviewed you is Dave Asprey. I would I’ve been following Dave Asprey and a whole bunch of other guys ⁓ probably since around 2012, 2013. And what I learned was how do I reduce the inflammation in my brain? And I had that one area of inquiry, the one area of inquiry that I could personally impact positively by taking out inflammatory foods from my diet. And before that it was, you know, ⁓ processed white bread, it was alcohol, it was cigarettes, ⁓ it was all the stuff that you get in a packet that doesn’t really help to nourish the body, right? So I went back to basics. We’ll call it just for the simplicity of the explanation, we’ll call it protein, ⁓ vegetables and basic carbohydrates like rice or potato. And then what I found was that inflammation decreased, and that was a game changer in how I experienced my brain. And it was a game changer in how quickly I improved neurologically. But just so that people know, it wasn’t the be all end all, it didn’t remove the damaged cells that still are in my head that mean I experienced my the left side of my body in a completely different way than my right side. I’ve got numbness, proprioception issues. I’ve got ⁓ tingling, I’ve got burning, I’ve got ⁓ spasticity, you know, the muscles are tight. So all that stuff is still there. But I have a better experience of the rest of my body and brain because of the things that I took out. But what I didn’t have was the link between exercise, which I do, light exercise, because I’m a stroke survivor. I can’t. use the left side of my body like I used to. so I would do exercise ⁓ like riding an electric bike because it’s easier to pedal, like walking and like doing very light weights at the gym. ⁓ but I didn’t have that oxygen part of the the therapy. And that’s kind of why I interviewed the guys about hyperbaric to understand how oxygen supports how mimicking i a hypoxic brain in the chamber supports ⁓ so how how does like what’s the next part like how does that support the brain to heal let’s give stroke survivors an understanding so that they can kind of grasp that I know we spoke about how oxygen gets into the ⁓ into the red blood cell we spoke about how it gets into the plasma but like Brad Pitzele (30:15) Yeah. BIll Gasiamis (30:20) Why is that the next step? Brad Pitzele (30:21) What’s it too? Yeah. It’s a good question. I think you’re right. I you know, we don’t I will say we don’t try to go out and pitch like exercise with oxygen therapy is a panacea or it’s everything for everyone. Even the name of our company, ⁓ one thousand roads, is about paying homage to everyone’s own healing journey and recognizing everyone’s unique journey. So I’ll say that, but So I’ll say that, but what I found about oxygen was in IWA in particular. What was fascinating to me was for me when I was dealing with Lyme disease, which similar to folks who are dealing with the stroke, there’s a variety of different symptoms and s from different causes. And I was trying to treat all these things with different protocols, different supplements that and I found that when I started digging into oxygen, I was shocked at how many of them came back to it. So when you have A stroke, often there’s a lot of ⁓ emerging research about mitochondrial dysfunction. And this is interestingly, mitochondrial dysfunction. Now ten years ago when I was researching it, no one heard of it or cared about it. And it’s really burst onto the scene because you’re gonna find it ⁓ At the heart of so many chronic health conditions, right? ⁓ you’re gonna it’s actually they’re looking at it in cancers, ⁓ chronic illnesses of all sorts, Alzheimer’s, all sorts of cognitive and ⁓ autoimmune conditions, etc., etc. So ⁓ you have this disrupted mitochondria, right? So there was a period of time when your cells were not getting enough energy, whether it was a hemorrhagic stroke and Blood wasn’t being delivered to those cells, so no nutrients, no oxygen, or an ischemic stroke where they were just cut off ⁓ because of a clot or whatnot. And so they were not getting nutrients. In each of these cases, what happens immediately when the cell runs out of oxygen, like I was talking about that brownout, it goes from aerobic respiration to anaerobic respiration. And anaerobic respiration, ⁓ it’s It only can produce 5% of the energy as aerobic. So the cell is in a low energy state, which is the first problem, which means it doesn’t have energy to repair, it doesn’t have energy to take out the trash, detoxify. so it’s kind of stuck. But also ⁓ it creates a lot of metabolic waste. So it creates lactic acid, it creates free radicals, all these things produce more inflammation, like you were talking about. So Now we’ve got these mitochondria, which are dysfunctional. They don’t have the energy to repair. They don’t have the energy to take out all these dead cells or ⁓ you know, all these other byproducts of the immune system and the natural kind of response to this damage, which then leaves more of it hanging around to produce more damage, and they’re producing more damage themselves. So it’s kind of like this swirl, and it’s ⁓ you know, it’s a downward swirl, if you will. ⁓ so When you can re-oxygenate the mitochondria, the first thing you’re doing is you’re giving them the energy to do whatever it is they need to do. ⁓ and that can be the immediate like feeling sharper, like, ⁓ I feel like I can get my thoughts together quicker. ⁓ it can be, ⁓ I feel like I’m more in control of my emotions. And I I don’t feel like sometimes I have a disproportionate emotional response to something. It can be I I don’t have that brain fog. ⁓ you know, that sort of thing. Or I literally have energy. So our brain actually consumes like 20% of all the oxygen in our body. And it’s only like two percent of the mass. So it’s like punching 10x its weight, right? So when your body starts running low on oxygen, it starts conserving. And the one of the things it tells you to do is like cool it, like stop using your muscles. You’re tired. You need to just sit there and veg out. BIll Gasiamis (34:06) Mm-hmm. Brad Pitzele (34:27) while our mitochondria try to catch up. And so that’s often that chronic fatigue that folks with a variety of health conditions, including stroke, feel, which is their bodies like, stop using energy, we don’t have enough. We need to redeploy it for something else more pressing. And so When you can reestablish normal oxygenation, it improves energy. ⁓ it improves sleep, it improves memory. and the the cells have energy to start repairing and detoxifying. ⁓ and then obviously I always think it’s cool because we’re pairing it with oc with exercise. And there’s so much research on the benefits of exercise. You mentioned it was so important, Bill, in in your healing journey. And you know, we know how important exercise is for a stroke survivor. Well, now we’re pairing it with oxygen and we’re using that exercise to catapult more of that oxygen around the body through the circulatory system while your blood vessels are dilated and opening up. So if you’re still dealing with blockages in your microcirculation, which most stroke survivors are. You’re opening them as wide as they they naturally can at that moment, and that’s when we’re feeding more oxygen to them. So it works it kind of hand in hand in that respect. BIll Gasiamis (35:48) All right. Now one glitch. Stroke survivors often are struggling to get into the physical recovery, right? Because the body goes offline, one of the legs doesn’t work, one of the arms doesn’t work. It’s a real challenge, right? So how how can we benefit from that even though we are at just after the acute phase where there is not a lot of capability for Brad Pitzele (36:00) Yes. It’s perfect. Yeah. BIll Gasiamis (36:17) physicality and I I say that so that the stroke survivors listening know that what I’m leading to is that early on it’s probably harder to do ⁓ physical therapy, exercise, et cetera. But again, with time and hope, all of those things can improve. Right. So I I wanna put that out there for stroke survivors, but also like it’s a can it’s a it’s a constraint. Brad Pitzele (36:48) Yeah. And you know, because a lot of our customers are dealing with chronic illness, this is a question that’s not uncommon is like, yeah, but I can’t I’m not out here to run a mile, Brad. I’m like eighty years old and I’m sick or whatever it is. The really ⁓ the really cool thing about ⁓ Ewatt is that it will meet you where you are at. So there is something all of us can do. The goal is to increase your heart rate and your circulation. Cost and Accessibility of Oxygen Therapy Devices and breathe the oxygen. So there’s a few ways you can do it. you know, it doesn’t have to be banging it out on a treadmill trying to get your seven minute mile. ⁓ you don’t need to do that. We have folks, you know, depending on where they are, you can start with slow walking on a treadmill. You can start with calisthenics. You can start with stretching. ⁓ gentle aerobics in your living room. You can start by, you know, lifting weights. You could be sitting and lifting weights with the the hand that’s not. We have folks, and this is probably not so much for ⁓ stroke survivors, but maybe jumping on a ⁓ a rebounder, like a little trampoline if you’ve got the balance one with the handle. ⁓ we have people using under-the-desk pedal bikes, the ones you can get for $49 on Amazon while you’re sitting. BIll Gasiamis (38:03) Beautiful. Brad Pitzele (38:04) while you’re sitting in a chair. And then for the folks who can’t do any of that, we have we even have them doing what I call passive Ewatt, which is they will breathe the oxygen while they get in like a an infrared ⁓ sauna blanket. So infrared sauna will increase your heart rate. And so you will get some benefit out of it. And what normally happens, the the really cool thing about exercising with oxygen is The first thing folks notice, the very first benefit most folks notice when they start doing is the exercise is easier. So I always describe this like if you were ⁓ jogging on a treadmill at, I don’t know, pick a number, you know, four miles an hour and you put the mask on, you wouldn’t feel like you were getting the same exercise at four miles an hour. You you crank it up to four and a half, and then later you crank it up more. And Your endurance actually improves much more quickly than if you were just doing exercise alone. ⁓ and there’s a ton of actually research on you know Olympic athletes using it for performance enhancement, which is not what we’re using for in this, but it’s kind of a nice little side effect. So we have folks who come to us who who are out of condition. We’re not talking about the physical disabilities, but out of condition, we’re like, I couldn’t do. And they’re shocked at what they’re doing and they come back and tell us in three months, look what I’m doing, sort of thing. ⁓ But it will meet you where you’re at. So if you want to do passive Ewatt, you can do that for a while as you’re working and as you start to feel better. Then maybe you’re using the under desk pedal bike. And as you’re getting your balance back and feeling better, maybe it’s a a real stationary bike later or walking on a treadmill and so on and so forth. ⁓ the goal isn’t to bust hump and like try to, you know, get a new record. As a matter of fact, I find that for most folks that sets you back. You wanna kind of you wanna do within an envelope that you’re comfortable with because If we work out too hard, also we set ourselves back because in most chronic health conditions and in stroke, additionally, we talked about this fatigue that’s due to an energy deficit. So if you go out there and overwork, you’re just putting your body in more of a deficit and potentially putting it in more of an inflammatory environment. And we’re trying to do this at a level that’s in you know anti-inflammatory and helping you recover. BIll Gasiamis (40:30) I love that. I love your whole explanation. So in my what I was hoping was you were gonna say that I could just sit there and almost do nothing ⁓ as a stroke survivor, where I’m completely in in just, you know, like week three of the acute after the acute phase, and fatigue is a massive issue and energy is a massive issue, and I’m barely able to stay awake, ⁓ and all of that stuff. And then ⁓ you could do just I hope you I was hoping you were gonna say, But you said the equivalent of ⁓ chair yoga, you know, where all I had to do was just move an arm or move a leg and do something just to get me physically going and then it would benefit. That’s what I love about it. The under-the-leg pedal bike, ⁓ under-the-desk pedal bike is one of the best things because you can strap in your leg with the deficits if you have a leg that has deficits, and you can do all the or the majority of the pedaling with the other leg, which is strapped in. Brad Pitzele (41:07) Mm. BIll Gasiamis (41:29) And you don’t you’re not gonna fall over ’cause you sit in in a chair. ⁓ probably you’re doing it inside your house so the the temperature, the weather is always perfect and ⁓ and you don’t have to door for long, right? You only have to door for a few minutes to start with. Brad Pitzele (41:45) And you’re pulling that other leg around and it’s starting to fire inside here and rebuild those connections. And and as you know, exercise increases ⁓ brain drive neurotrophic factor, which is a growth factor in our brain for BIll Gasiamis (41:51) Mm. Brad Pitzele (42:00) neuroplasticity. So you’re getting you’re getting all of these benefits. So you to your point, for someone who’s if it’s my right leg’s not working and I’m strapped in and my left leg’s doing it, my right leg is firing and it’s firing those neurons at the exact time you have that B D N F as it’s called. So BIll Gasiamis (42:17) BDNF’s amazing. And I also interviewed ⁓ recently a gentleman who ⁓ had spoken about ⁓ Jack Clifford on episode 402 who spoke about kind of ⁓ a protocol that enables you to regenerate blood vessels around the area that’s injured ⁓ to increase the oxygenation and the blood flow ⁓ to potentially those areas where ⁓ brain is offline, not dead. ⁓ so all of these things, ⁓ the previous episode that I recorded with Jack, your episode right now, like all are things that you can do that support brain health, brain recovery, ⁓ overcoming all the some of the challenges that stroke causes. And what I love about this specifically is that you can do it from your house. and you don’t have to go anywhere, but there is a cost. So let’s talk about the cost a little bit because I I want to mention it because of the massive difference to hyperbaric, which can cost up to sixty grand if you go on the right protocol. And ⁓ that’s unattainable for most people, let alone a stroke survivor who just lost their ability to earn ⁓ and may not have sixty grand to splash. Brad Pitzele (43:48) Yeah. BIll Gasiamis (43:48) ⁓ so what is the cost of getting a machine, setting it up and putting it in your house? Brad Pitzele (43:54) Yeah. So we sell two different machines. ⁓ we have one machine that’s eighteen hundred and ninety-nine dollars and the other one that’s twenty-four ninety-nine. ⁓ that’s everything you need to get going other than the exercise equipment. and the machines last a long, long time. I think I You know, I think we actually we’ve been in business since 2018 and we had our first customer come back and tell us they wore out their machine like this year. So I have to stop saying we’ve never had one wore wear out yet. So we’ve had one. ⁓ so it it’s one of I think that’s one of the things that’s great about it is it’s something you can do in your house. It’s something that doesn’t take a lot of time. When I was dealing with my chronic health issue, I was joke around about the ceremonies of counting pills and doing this modality and doing that. And they all in stroke survivors, I think, recognize the same thing. It starts to crowd out your life. And then eventually you kind of throw your hands up. You’re like, I it might be helping, but I just don’t have four hours a day for all this stuff. Like I just I need to go on and and live my life too. So it’s something that ⁓ it’s 15 minutes. You do it three to five times a week in your home. ⁓ it’s a one time expense and then it’s you know, it’s something you’ll have for many, many years. BIll Gasiamis (45:12) I love it. Where are you located? Brad Pitzele (45:15) We’re in a Dallas, Texas area. BIll Gasiamis (45:17) Okay. And are these things easy to get and distribute throughout the United States and other places in the world? I don’t know I’ve never heard of it before. So are there other people around who who sell a product that’s similar or can you access them easily? Brad Pitzele (45:35) Well, we do ship worldwide. ⁓ we ship with US power, so people get a power converter we’ve sold to the UK, to Australia, to all over Europe, Asia, ⁓ South America, ⁓ and of course across North America as well. So ⁓ they’re readily accessible. Kind of our mission was You know, when the doctor asked me if I’d make him first patients, I I I I thought about what you were saying about how like spending sixty grand to find out if something’s gonna work. And I felt like I was taking advantage a lot when I was very ill. So we wanted to make something that was accessible to people who are chronically ill. They might not have the ability to earn money. They’re on a fixed in like I have a I guess a deep personal experience and empathy there sort of thing. So ⁓ that’s yeah. So we ship worldwide. BIll Gasiamis (46:27) Yeah. If somebody wanted to reach out to you just to get more information, to have a chat with you, to look at your website, where would they go? Brad Pitzele (46:35) They would go to 1000roads.com slash stroke recovery. We do. And you can find it at the bottom of that webpage, but it’s 1000 Roads HQ. BIll Gasiamis (46:42) And you have a YouTube channel. Okay. What kind of ⁓ things can people find on the YouTube channel? Brad Pitzele (46:56) you can find everything about protocols, benefits, ⁓ how to use it. ⁓ we hit have some customer testimonials and parts of that. ⁓ just talking about the science of it, people’s experience with it, et cetera, et cetera, different use reasons people use it. BIll Gasiamis (47:17) I think it’s very important to bring information like this to stroke survivors so that they can access things in their own home that’s going to make their life better. I wrote a book, The Unexpected Way That a Stroke Became the Best Thing That Happened, for the explicit reason to give people like a path forward, a journey forward as to how to ⁓ s how to kind of obtain the silver lining in stroke recovery. And when I wrote it ⁓ in 2018, when I started writing it, something like that, 2018, 2019, I was lacking a lot of the extra pieces that I could put into ⁓ the mindset chapter, for example, or the exercise chapter, or, you know, the nutrition chapter. And In the last five or six years, I’ve been picking up those pieces to sort of attach to those chapters because they’re really relevant. And with the exercise chapter, I think this protocol was the one thing that was missing because I made the point of how important exercise was. I didn’t make the point of how you can exercise and get more bang for your buck during that exercise by Increasing the amount of oxygen that you were getting into your ⁓ bloodstream. How would I have known that if I hadn’t come across the science, which I hadn’t? Plus, there’s only so much you can put in each chapter, but this is the perfect addition. Like, and I love it. So I can go on and on about how much I think this is amazing. Brad, I really ⁓ want to thank you for reaching out and joining me on the podcast. Thanks for the work that you do. I’m glad that you’ve been able to get your health back and now you’re helping other people. Brad Pitzele (49:06) Thank you so much, Bill. I appreciate you having me on. BIll Gasiamis (49:08) Well, that’s it for another episode of the Recovery After Stroke podcast. I hope you enjoyed this episode. Might be worth listening to it again. The science here is worth sitting with, oxygenating the blood plasma, reopening inflamed microcapillaries, giving mitochondria what they need to shift out of that low energy state. And the fact that it can be done at home at a fraction of the cost of hyperbaric oxygen therapy makes it worth knowing about. If you want to learn more, or explore the equipment, head to 1000Roads.com Stroke Recovery. Brad has arranged a discount for listeners of this show of between one and 500 dollars, depending on the package you choose. This episode pairs well with the episode 402 with Jack Clifford, which covers a protocol for regenerating blood vessels around the injured area of the brain. The two conversations complement each other. Worth going back to if you haven’t heard it yet. Now, if this episode was useful, please share it with someone who could benefit. And my book, The Unexpected Way That a Stroke Became, the Best Thing That Happened, is available at recoveryafterstroke dot com slash book. And if you’d like to support the show financially, I would love it if you could. You can go and do that via patreon.com/slash recovery after stroke. I’m Bill Garciamas. Thanks for listening. See you on the next episode. The post Brad Pitzele – How Exercise With Oxygen Therapy Brings Hyperbaric-Style Benefits Home appeared first on Recovery After Stroke.

In this episode of The Jimmy Rex Show, Jimmy sits down with Paul Barattiero, founder of Echo Water and one of the leading voices in hydrogen water research.Paul shares the personal story that launched his mission after watching his wife's health dramatically improve from chronic illness. The conversation dives deep into hydration, gut health, inflammation, oxidative stress, recovery, anti-aging, athletic performance, and the growing body of research surrounding molecular hydrogen.They discuss why hydration may be the most overlooked health habit, how gut health impacts nearly every disease process, and why many professional athletes, biohackers, and longevity experts are paying attention to hydrogen water.Whether you're focused on performance, recovery, longevity, or simply feeling better, this episode challenges conventional thinking about one of the most basic elements of human health.Follow Dr. Paul Barattiero: IG

Full Show Notes: https://bengreenfieldlife.com/timelinereplay In this special replay episode with repeat guest Dr. Anurag Singh from Timeline Nutrition, you'll explore the science of cellular health and longevity, including why mitochondrial function affects everything from energy and muscle performance to cognitive clarity and how well you age. Dr. Singh explains how urolithin A, a postbiotic compound derived from foods like pomegranates and berries, activates mitophagy, the body's cellular clean-up system that clears out worn-out mitochondria and replaces them with new ones, and how clinical research shows it can support muscle strength, endurance, immune resilience, and cognitive function. You'll also hear how diet, gut health, exercise, sleep, and recovery work alongside urolithin A to build a stronger, more resilient physiology over time. Dr. Anurag Singh is Chief Medical Officer at Timeline Nutrition, with an M.D. in internal medicine and a Ph.D. in immunology. He has authored more than 50 scientific articles, been awarded over 20 patents, and led more than 50 randomized clinical trials. His decade of research on urolithin A has produced multiple clinically validated products bringing longevity science directly to consumers. Episode Sponsors: BON CHARGE: A holistic wellness brand with products that address sleep, performance, recovery, hormone balance, and inflammation. Go to boncharge.com/GREENFIELD and use code GREENFIELD to save 15%. Troscriptions: A buccal troche delivery system that bypasses digestion to deliver pharmaceutical-grade compounds directly through your cheek mucosa for faster onset and higher bioavailability. Visit troscriptions.com/BEN or use code BEN for 10% off your first order. Timeline: High-performance products powered by Mitopure, delivering a precise dose of urolithin A for healthy aging. Mitopure starts at $79 at timeline.com/BEN. Just Thrive: The Gut Essentials Bundle pairs a probiotic clinically proven to arrive 100% alive in your gut with Digestive Bitters, a blend of 12 science-backed herbs. Visit justthrivehealth.com/BEN and save 20% with code BEN, or get a full refund if you don't notice a difference. Young Goose: To experience the transformative power of Young Goose's cutting-edge skincare products, visit younggoose.com and use code BGF10 at checkout to enjoy a 10% discount on your order. Manukora: You haven’t tasted or seen honey like this before, so indulge and try some honey with superpowers from Manukora. If you head to manukora.com/ben or use code BEN, you’ll automatically get $25 off your Starter Kit. See omnystudio.com/listener for privacy information.

What if the foods marketed as “healthy” are actually contributing to the very symptoms so many women are struggling with today? In this eye-opening conversation, Dr. Mariza sits down with Julia Putzeys, certified Nutritional Therapy Practitioner and founder of the Trash Panda app, to expose the hidden reality of ultra-processed foods and how they impact energy, hormones, metabolism, mood, inflammation, and long-term health. Together, they unpack the confusing world of food marketing, ingredient labels, food additives, artificial flavors, seed oils, and the growing prevalence of ultra-processed foods in the modern food supply. Julia shares her own journey from believing she was eating healthy to discovering how many seemingly nutritious products were filled with ingredients that offered little nourishment and often contributed to poor health outcomes. They also discuss the powerful mindset shift from calorie counting and restriction toward nourishment, nutrient density, and real food. As mothers, both Dr. Mariza and Julia share practical strategies for helping children develop a healthier relationship with food while avoiding the traps of hyper-palatable, addictive processed products. If you've ever felt overwhelmed at the grocery store or questioned whether the foods in your pantry are actually supporting your health, this episode offers practical guidance and empowering tools to help you make more informed choices. JULIA PUTZEYS Julia Putzeys is a certified Nutritional Therapy Practitioner, founder of the Trash Panda app, and mother of three. Combining her background in software product management with her passion for nutrition, Julia created Trash Panda to help consumers quickly identify potentially harmful ingredients in packaged foods and discover healthier alternatives. Her mission is to make ingredient transparency and healthier food choices more accessible to families everywhere. IN THIS EPISODE Why over 70% of grocery store products are considered ultra-processed foods The difference between processed foods and ultra-processed foods How food additives, flavorings, and dyes impact cravings, behavior, and long-term health Why calorie counting often distracts us from focusing on true nourishment The connection between ultra-processed foods, inflammation, metabolic dysfunction, and chronic disease How food marketing creates confusion around what is actually healthy Practical strategies for helping children develop healthier eating habits How the Trash Panda app helps consumers identify healthier food swaps QUOTES“Eating whole food means reading the ingredients, not just the nutrition label.” “Your body becomes addicted to ultra-processed foods because they're designed that way.” “When I started focusing on real food, I had so much less food noise.” RESOURCES MENTIONED Use code ENERGIZED and get $10 off on annual membership for the Trash Panda App on IOS https://apps.apple.com/redeem Download the Trash Panda App now on IOS or Android https://trashpanda.app.link/AvwFh7mfG3b Use code ENERGIZED and get 10% off on your MitoQ Order https://www.mitoq.com/energized%C2%A0 Trash Panda App Website Trash Panda App Instagram Trash Panda App Facebook Trash Panda App Youtube RELATED EPISODES  751: Bloating, Brain Fog & Hormone Chaos? Your Gut May Be the Root Cause with Dr. Cassie Smith 741:Estrogen, Gut Health, Mitochondria, and Cardiovascular Health: What Changes In Perimenopause with Dr. Siobhan Mitchel 743: Why Your Heart Risk Changes in Menopause (And What You Can Do About It) with Dr. Jayne Morgan 717: “I Don't Feel Like Myself Anymore”: The Mental & Emotional Reality of Perimenopause

Episode Highlights With AnnKey ways to future proof fertility and protect mitochondria to have healthy pregnancies, even as we get olderNew studies show mitochondria in eggs are preserved better than other parts of the bodyHow minimizing toxins is protective of fertility in a major wayWays to lower inflammation to protect fertility The dramatic decline in sperm quality and count in the last few yearsMale infertility and how health of sperm can impact the pregnancy Why there are often many other things couples can do even if they've been told they can only do IVFIn most cases, it's possible to help the body get to a place of health and thriving without IVF to conceive naturallyA few situations where IVF does make sense as a first resort The most important factors to focus on to future proof fertilityHow protein and movement come into play for optimal fertility A message of hope and incredible stories of how the body can heal and thrive at any ageResources MentionedThe Preconception Revolution bookHer websiteFollow Ann on Facebook or InstagramHiyaHiya created a super powered chewable vitamin for kids that packs twelve organic fruits and vegetables plus fifteen essential vitamins and minerals into every dose. Try it at hiyahealth.com/wellnessmama for 50% off your first order.Just Thrive:Just Thrive Health has been one of my longtime favorite brands for gut health and they have an amazing Daily Gut Detox. Your immune system, gut barrier, and digestion get the support they need to stay strong and healthy. You can find this and their probiotics at justthrivehealth.com/wellnessmama or use code wellnessmama for 20% off your order. 

What if the key to better energy, faster recovery, sharper focus, and healthier aging has been hiding in the smallest molecule on Earth? Greg 'The Hydrogen Man' and I uncover why TRUE hydrogen water is becoming one of the biggest breakthroughs in wellness, performance, and cellular health. Unlike ordinary water, molecular hydrogen works at the cellular level—helping combat oxidative stress, support mitochondrial function, reduce inflammation, and optimize overall vitality.But here's the catch… not all hydrogen water is created equal. Many products on the market lose potency quickly or fail to deliver therapeutic levels of hydrogen. So what makes TRUE hydrogen water different?If you've been struggling with fatigue, brain fog, poor recovery, low energy, or accelerated aging, this episode could completely change the way you think about hydration and health.Supplements Featured In This Episode:• Acceleradine® Iodine https://www.acceleratedhealthproducts.com/products/acceleradine-iodine-supplement  • Accelerated Methylene Blue® https://www.acceleratedhealthproducts.com/products/accelerated-methylene-blue-supplement Not sure what food to eat and avoid? This guide is for you.⬇️

“What if your bloating, fatigue, brain fog, anxiety, stubborn weight gain, and hormone symptoms are actually starting in your gut?” In this episode, Dr. Mariza sits down with Dr. Cassie Smith — dual board-certified endocrinologist, founder of Modern Endocrine, and author of Fix Your Gut, Fix Your Hormones — to unpack the powerful connection between gut health, hormone balance, stress, metabolism, inflammation, and reproductive health. Together, they dive into how chronic stress, poor gut health, blood sugar dysregulation, inflammation, and lifestyle overload silently impact everything from cortisol and insulin to estrogen, progesterone, thyroid function, and fertility. Dr. Cassie explains why so many women are told their labs are “normal” while still feeling exhausted, bloated, anxious, inflamed, and disconnected from their bodies — and why gut dysfunction is often the missing piece conventional medicine overlooks. They also explore the growing metabolic and hormonal crisis happening in younger women, the connection between PCOS, insulin resistance, gut dysfunction, and birth control, and why many women are struggling to restore healthy cycles and fertility later in life. This conversation is a powerful reminder that hormones do not work in isolation. Your gut, nervous system, metabolism, sleep, stress resilience, and hormones are all deeply interconnected. If you've been feeling like your body is trying to tell you something but nobody has connected the dots yet, this episode will help you understand where healing truly begins. DR. CASSIE SMITH Dr. Cassie Smith is a dual board-certified endocrinologist and the founder of Modern Endocrine. After becoming frustrated with the limitations of conventional medicine, she built a practice focused on uncovering the root causes behind hormone dysfunction, metabolic issues, fertility struggles, and gut-related symptoms. She is also the author of the book Fix Your Gut, Fix Your Hormones. IN THIS EPISODE Why chronic stress has such a powerful impact on gut health and hormones How gut dysfunction contributes to fatigue, brain fog, bloating, anxiety, and weight resistance The connection between estrogen decline, microbiome diversity, and inflammation Why insulin resistance and metabolic dysfunction are rising in younger women The hidden relationship between PCOS, gut health, cortisol, and fertility Why birth control is often used as a Band-Aid instead of addressing root causes The foundational lifestyle habits that support gut and hormone healing Why slowing down, resting, and reducing nervous system overload matters for recovery QUOTES “Your hormones are doing the best they can in the environment you give them.” “It doesn't matter how many supplements or hormones we throw at you if the foundations aren't in place.” “Your gut is where all healing begins.” “Your body cannot heal in survival mode.” RESOURCES MENTIONED Get your “Fix Your Gut, Fix Your Hormones” Book by Dr. Cassie Smith https://guthormonefix.com/ ⁠Order my newest book: The Perimenopause Revolution https://peri-revolution.com/ Modern Endocrine Website Modern Endocrine Instagram Modern Endocrine Facebook Modern Endocrine Tiktok Modern Endocrine Youtube Hormones, Metabolism and You PodcastThe Menopause Gut Book by Cynthia Thurlow RELATED EPISODES  741: Estrogen, Gut Health, Mitochondria, and Cardiovascular Health: What Changes In Perimenopause with Dr. Siobhan Mitchel 743: Why Your Heart Risk Changes in Menopause (And What You Can Do About It) with Dr. Jayne Morgan 738: The Hidden Link Between Inflammation, Hormones & Fertility with Dr. Natalie Crawford  740: Why You're Bloated, Gaining Weight & Feeling Off in Menopause (It Starts in Your Gut) with Cynthia Thurlow

You do the work. You train, you sleep, you eat well, you manage stress. And yet your joints still ache, recovery takes longer, and something just feels harder than it used to.I sit down with David Watumull, co-founder and CEO of AX3, to talk about astaxanthin, a naturally occurring antioxidant he has spent his entire career studying, one that most people have never heard of despite having more than 4,000 peer-reviewed papers and 100 human clinical trials behind it.This is not a conversation about the latest wellness trend. It's a deep look at the science of oxidative stress, chronic inflammation, and what actually happens inside your cells when the damage accumulates faster than your body can repair it.What we explore:- Why astaxanthin is categorically different from vitamins C and E, and how it works at every layer of the cell without ever becoming pro-oxidant.- How chronic inflammation starts with oxidative stress upstream, and why blocking it at the source is safer than suppressing the immune response after the fact.- Why this ingredient was one of only five agents in a 20-year NIH-funded program to extend mammalian lifespan by over 10 percent while also showing health span benefits.- How astaxanthin protects joints, muscles, and mitochondrial energy production, and what the data on competitive cyclists actually demonstrates.- What to look for in a supplement, why bioavailability determines whether you absorb anything at all, and how to build astaxanthin into a foundational daily stack.Chapters: 00:00 Intro03:30 Why Astaxanthin Isn't Like Other Antioxidants07:14 The Algae Origins of Astaxanthin11:22 Salmon, the Food Chain, and Nature's Design15:00 From Pharma Research to Supplement18:21 The NIH Longevity Study Explained23:15 mTOR, FOXO3, and the Aging Pathways29:10 Safe Anti-Inflammatory for Joints and Athletes35:15 Brain Protection and the Blood-Brain Barrier38:02 Skin Health and Sun Damage from the Inside45:00 Redox Balance and Liver Protection48:35 Mitochondria, Energy, and Endurance Performance53:00 How to Stack Astaxanthin with Other Supplements57:10 Dosing, Bioavailability, and What Sets AX3 Apart01:07:00 Why David Watumull Went All-In on One IngredientAbout David Watumull:David Watumull is the co-founder and CEO of AX3, a supplement company built on more than two decades of astaxanthin research. He was introduced to the ingredient as a teenager working on algae ponds on the Big Island of Hawaii, and has spent his career advancing its science through pharmaceutical-grade manufacturing, NIH-funded longevity studies, and peer-reviewed cardiovascular research. His work sits at the intersection of rigorous science and practical supplementation, and it shows.Connect with David Watumull:Instagram: https://www.instagram.com/davewatumull–This episode is sponsored by:AX3: Visit ax3.life and use code GABBY for 20% OFF your first orderWebsite: https://www.ax3.lifeInstagram: https://www.instagram.com/ax3.life–The Gabby Reece ShowThis is where I have real conversations with the people I find most worth listening to: scientists, athletes, coaches, parents, and thinkers who are doing the hard work of building a life that holds up over time. No hacks. No quick fixes. Just honest, practical conversations about performance, longevity, relationships, and what it actually takes to show up well at every age.If you are here, you probably already know that health is not a destination. It is how you live. I am glad you are along for it.Connect with Gabby Reece:Instagram: https://www.instagram.com/gabbyreece/TikTok: https://www.tiktok.com/@gabbyreeceofficialWebsite: https://gabriellereece.comPlease note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.Produced by Dear Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

You're training consistently, eating well, sleeping as best you can and yet the energy isn't there, recovery is taking longer, and something just feels off.  Brad Currier, one of the leading researchers in mitochondrial science, gets into why mitochondrial decline is the hidden driver behind low energy, slower recovery, and reduced muscle performance in women over 40 and what the latest clinical research shows you can actually do about it. If you want to train hard, recover well, and feel genuinely energetic into your 40s and beyond, this one is worth your full attention.  WHAT YOU'LL LEARN • Why mitochondria decline with age and what it means for energy and recovery after 40 • What mitophagy is and why most active women in their 40s should know this • How urolithin A triggers mitophagy and what the clinical data actually shows • What rep range builds strength and longevity for women in their 40s • How exercise improves skin health and collagen from the inside out VALUABLE RESOURCES • Take the BioSyncing Quiz to help you understand what's actually happening in your body — and how to fix it.

This week on Press B to Cancel, we're diving into the 1998 PlayStation classic Parasite Eve. The game that made you rethink everything your biology teacher told you about mitochondria. Part RPG, part survival horror, and entirely unforgettable, Parasite Eve dropped players into a nightmare New York City where the real monster was hiding inside every living cell. Press B To Cancel also on YouTube! For updates and more episodes please visit our website www.pressbtocancel.com, or find us on Twitter @pressbtocancel Want to support the show? Donate via our Patreon and gain additional Discord perks and behind the scenes clips. Press B is a member of the SuperPod Network; a gaming collective of fellow podcasters and shows. Special thanks to The Last Ancient on SoundCloud for our podcast theme. Find out more at http://pressbtocancel.com

What if your fatigue, brain fog, stubborn weight gain, slow recovery, and lack of motivation all traced back to one hidden problem inside your cells?Your mitochondria are the tiny energy factories that power every organ, every thought, every heartbeat, and every movement you make. But modern stress, toxins, poor nutrition, aging, and environmental overload are silently damaging them—leaving millions running on empty.In this eye-opening episode, I reveal the ultimate biohacker's guide to mitochondrial support supplements and how optimizing your cellular energy can completely transform your health, metabolism, performance, and longevity.If you're constantly tired, battling brain fog, struggling to lose weight, or looking for the next level of health optimization, this episode could change how you think about energy forever. Supplements Featured In This Episode:• Acceleradine® Iodine https://www.acceleratedhealthproducts.com/products/acceleradine-iodine-supplement  • Accelerated Liver Care® https://www.acceleratedhealthproducts.com/products/accelerated-liver-care• Accelerated AMINOS® https://www.acceleratedhealthproducts.com/products/accelerated-aminos • Accelerated BIO PEPTIDES™ https://www.acceleratedhealthproducts.com/products/accelerated-collagen-peptides• Accelerated Scalar Copper® https://www.acceleratedhealthproducts.com/products/accelerated-scalar-copper • Accelerated Methylene Blue® https://www.acceleratedhealthproducts.com/products/accelerated-methylene-blue-supplement Not sure what food to eat and avoid? This guide is for you.⬇️

This episode is brought to you by Energy Bits. Most people are exhausted, inflamed, undernourished, and aging faster than they should be—and the modern food system is making it worse. While supplements promise quick fixes, few address the real root cause of chronic disease: mitochondrial dysfunction, oxidative stress, nutrient depletion, and inflammation at the cellular level. In this conversation, algae nutrition pioneer Catharine Arnston breaks down the shocking science behind spirulina and chlorella, why NASA compared algae nutrition to "1,000 grams of vegetables," and how these compounds may support brain health, cardiovascular function, detoxification, gut health, fertility, metabolic health, and longevity. Chase and Catharine also dive into ATP production, oxidative stress, serotonin, men's health, women's health, detoxification, inflammation, and why algae could become one of the most important functional foods of the next decade. Follow Catharine @catherinearnston Follow Energy Bits @energybits Follow Chase @chase_chewning ----- 00:00 — Intro 01:12 — What Algae Actually Is (And Why Most People Misunderstand It) 04:24 — Spirulina vs Steak: The Protein Density Debate 07:45 — 100,000 Studies on Algae & Human Health 11:16 — The Modern Nutrition Crisis Explained 12:20 — Why Most Algae Supplements Lose Their Potency 18:48 — Cardiovascular Disease, Inflammation & Spirulina Research 22:00 — How Spirulina Supports ATP & Cellular Energy 24:49 — Mitochondria, Free Radicals & The Electron Transport Chain 31:24 — Why Chronic Disease Accelerates After Age 40 36:34 — Brain Health, Neuroinflammation & Alzheimer's Prevention 39:22 — PTSD, Brain Scans & Veteran Recovery Results 41:37 — Cancer, Cellular Alkalinity & Otto Warburg's Research 43:15 — Men's Health, Iron Overload & Oxidative Stress 47:36 — Why Most Supplements Don't Work Synergistically 53:06 — Spirulina Dosage, Timing & Daily Use 55:04 — Blood Flow, Nitric Oxide & Erectile Health 57:57 — Chlorella for Detoxification, Gut Health & Recovery 59:58 — Chlorophyll, Serotonin & Gut-Brain Connection 01:04:55 — Constipation, Digestion & Natural Detox Strategies 01:06:22 — Catharine's Biological Age & Longevity Testing 01:08:46 — Shark Tank Rejection & Building EnergyBits 01:11:57 — Why Algae Is Still Misunderstood in America 01:16:23 — What "Ever Forward" Means to Catharine Arnston ----- Episode resources: Save 20% on Energy Bits with code EVERFORWARD  Watch and subscribe on YouTube Catharine first appeared in episode 474

“What if the exhaustion, brain fog, low libido, and metabolic changes women experience in midlife are actually rooted in a deeper cellular energy crisis?” In this episode, Dr. Mariza sits down with Dr. Andrew Salzman — physician, inventor, biochemical engineer, and Chief Scientific Officer of Wonderfeel — to unpack the powerful connection between NAD, mitochondrial health, inflammation, ovarian aging, gut integrity, nitric oxide, and the dramatic energy shifts women experience during perimenopause and menopause. Dr. Salzman explains why menopause represents a major biological inflection point for women and how declining NAD levels may be contributing to fatigue, brain fog, poor recovery, metabolic dysfunction, sleep issues, reduced stress resilience, cardiovascular changes, and shifts in sexual health. Together, they explore the evolutionary role of menopause, why ovarian senescence accelerates aging pathways, how inflammation and the enzyme CD38 rapidly deplete NAD stores, and why the gut microbiome may be one of the biggest drivers of inflammation and energy decline in modern women. They also dive into nitric oxide production, cardiovascular health, the brain's dependence on NAD for sleep and cognitive function, and why ingredients like NMN and creatine are gaining attention for supporting healthy aging and resilience in midlife. If you've ever looked in the mirror and thought, “I don't feel like myself anymore,” this conversation will help connect the dots between your symptoms, your mitochondria, and your long-term vitality. ANDREW SALZMAN Dr. Andrew Salzman is a physician, inventor, biochemical engineer, and the Chief Scientific Officer of Wonderfeel. With more than 30 years of experience in drug discovery and development, over 170 scientific publications, and more than 50 patents, Dr. Salzman has spent decades studying aging biology, inflammation, cellular resilience, nitric oxide signaling, and mitochondrial health IN THIS EPISODE Why menopause is a major biological inflection point for women How declining NAD levels impact energy, metabolism, sleep, and brain function Why CD38 accelerates inflammation and NAD depletion during aging The surprising connection between gut health, inflammation, and menopause symptoms How estrogen decline contributes to leaky gut and systemic inflammation Why nitric oxide is essential for circulation, libido, cardiovascular health, and cognition The role of NAD in circadian rhythm, sleep quality, and stress resilience Why NMN and creatine are gaining attention for healthy aging and vitality QUOTES“Menopause will happen, but the question is: how do we maintain vibrancy and resilience through it?” “NAD is the common currency that drives energy throughout the body.” “The gut is the foundational driver of inflammation as we age.” “Without NADPH, you don't have nitric oxide production.” RESOURCES MENTIONED Subscribe and Save $15 on Wonderfeel Youngr™ NMN: https://tidd.ly/4rPnckS Use code ENERGIZED and get 30% off on your first BATCH order https://hellobatch.com/ENERGIZED Order my newest book: The Perimenopause Revolution https://peri-revolution.com/ Wonderfeel Website Wonderfeel Instagram Wonderfeel YouTube RELATED EPISODES  741: Estrogen, Gut Health, Mitochondria, and Cardiovascular Health: What Changes In Perimenopause with Dr. Siobhan Mitchel 691: The Fertility Crisis No One Talks About: Why Your Health Today Impacts Future Generations with Dr. Ann Shippy 717: “I Don't Feel Like Myself Anymore”: The Mental & Emotional Reality of Perimenopause 743: Why Your Heart Risk Changes in Menopause (And What You Can Do About It) with Dr. Jayne Morgan

In this episode, Dr. Hugh explains how unstable blood sugar can hurt your mitochondria and lower your energy. This problem is called dysglycemia.To learn more or schedule a Zoom call with Dr. Hugh, visit:https://drhughwegwerth.com/discovery-call/When blood sugar goes too low or too high, your cells may not get steady fuel. This can lead to poor energy, brain fog, fatigue, poor sleep, and slower healing.Dr. Hugh explains why the blood sugar “sweet spot” is important for people with chronic illness, autoimmune issues, fibromyalgia, gut problems, thyroid problems, and people recovering from antibiotic damage.In this episode, you will learn:Why blood sugar matters for mitochondrial healthHow low blood sugar can create stress in the bodyHow high blood sugar can cause inflammation and oxidative stressWhy stable blood sugar may improve energy and focusWhy Dr. Hugh likes the blood sugar range of 85 to 120How a continuous glucose monitor can help find hidden blood sugar problemsWhy blood sugar is one of the “low-hanging fruits” in healingHow poor blood sugar control may slow recoveryWhy anemia and low blood pressure also matter for healingDr. Hugh also shares a real client example showing how eating more consistently helped improve sleep and energy. He explains how tracking blood sugar can reveal patterns that regular testing may miss. Key takeaway:If your blood sugar is going too high or too low, your mitochondria may struggle to make energy. Before spending money on advanced therapies, it is important to check the basics first.To learn more or schedule a Zoom call with Dr. Hugh, visit:https://drhughwegwerth.com/discovery-call/

Start Being a Student of Your Health: Dr. Henry Ealy on Nutrition, Energy, and Healing Episode Description In this episode of Conversations with a Chiropractor, Dr. Stephanie Wautier sits down with Dr. Henry Ealy, also known as Dr. H, founder of the Energetic Health Institute. Dr. Ealy is a teacher, healer, curriculum developer, and natural health educator whose work centers on a powerful idea: people should not just be passive patients, they should become active students of their own health. This conversation moves through nutrition, energy, mitochondria, red light therapy, environmental stressors, EMFs, grounding, detoxification, and the importance of learning how the body is designed to heal. The conversation also touches on environmental health concerns, including air quality, chemtrails, infrared sauna use, sweating, and how Dr. Ealy thinks about reducing the body's toxic burden. Dr. Ealy shares why he believes the foundation of health education should begin with nutrition, and why understanding the body's energy production can change how people think about fatigue, symptoms, and long-term wellness. Stephanie and Dr. Ealy also talk about the confusion many people feel when trying to make healthier choices. From supplements and red light tools to grounding products and natural healing approaches, it can be difficult to know what is real, what is marketing, and what is worth trusting. This episode includes strong perspectives, challenging ideas, and a call for deeper curiosity. It is meant to inform, spark thought, and encourage personal responsibility, not replace individualized medical care. If you are making changes to your health, medications, supplements, detox practices, fasting, or treatment plan, work with a qualified healthcare professional who understands your personal situation. In This Episode, Discover Dr. Henry Ealy's early experiences with medicine and how they shaped his path Why he believes the word "doctor" should mean "teacher" The difference between being a passive patient and becoming a student of your health Why nutrition is central to Dr. Ealy's approach to healing and education How the Energetic Health Institute teaches holistic nutrition, detoxification, and natural medicine Why Dr. Ealy believes mitochondrial energy production is a key part of understanding health The role fatigue may play as a common thread in many health challenges How nutrition, chiropractic, bodywork, acupuncture, and exercise may work better when the body is properly supported Why consumers need help sorting through health products, supplement claims, and wellness marketing What Dr. Ealy looks for when evaluating companies and products he trusts How red light therapy, grounding, sleep, and daily routines fit into his larger health philosophy The conversation around EMFs, environmental toxins, air quality, chemtrails, and toxic burden Why Stephanie and Dr. Ealy emphasize doing your homework before trying intense cleanses, detoxes, or supplements The purpose of the Healing Made Easy membership Why small steps, repeated over time, may help people feel more confident and capable in their own health journey Stay Connected & Explore Learn More About Dr. Henry Ealy and the Energetic Health Institute: Energetic Health Institute: https://www.energetichealthinstitute.org/ Meet Dr. H: https://www.energetichealthinstitute.org/meet-dr-h/ Healing Made Easy: https://www.energetichealthinstitute.org/healing-made-easy/ Companies We Trust: https://www.energetichealthinstitute.org/companies-we-trust/ Books by Dr. Ealy / Dr. Henele: https://drhenele.com/ Connect with Conversations with a Chiropractor: Follow Us on YouTube: http://www.youtube.com/@ConversationswithaChiro Follow Dr. Stephanie on Facebook: https://www.facebook.com/wautierwellness Email for show-related inquiries and sponsorships: drstephaniewautier@yahoo.com Want to be a guest on Conversations with a Chiropractor? Send Stephanie Wautier a message on PodMatch, here: https://www.podmatch.com/hostdetailpreview/drstephanie Credits Podcast production by Brand|Sound. Start your podcast journey by emailing brandsoundpodcasts@gmail.com. Chapters 00:00 Introduction to Conversations with a Chiropractor 00:56 Meet Dr. Henry Ealy 01:23 Dr. Ealy's Early Memories of Medicine 04:37 Chiropractic, Natural Medicine, and the History of Medical Opposition 08:27 Reclaiming Health and Becoming a Student 10:04 Why Nutrition Belongs at the Center of Health Education 13:04 Nutrition, Modern Medicine, and the Problem of Limited Training 17:48 Building Better Health Education Through the Energetic Health Institute 19:05 Doctor as Teacher, Patient as Student 20:41 Mitochondria, Energy, and the Body's Electrical Systems 23:35 Taking Responsibility for Your Own Health 27:08 Nutrients, Multivitamins, and Reading the Body 28:39 How Nutrition Supports Other Healing Modalities 30:10 Healing Made Easy and Support for Everyday Health Seekers 33:51 Red Light Therapy, Sleep, and Restorative Routines 37:04 Testing Products and Finding Companies You Can Trust 40:17 The Book of Questions and Doing Today's Work 43:08 Staying Hopeful While Facing Modern Health Challenges 45:45 Environmental Exposures, Chemtrails, Sweating, and Detoxification 51:59 Infrared Sauna, Red Light, and Energy Production 59:25 Why Self-Experimentation Requires Caution 1:01:12 Supplements, Integrity, and Trust in Natural Health 1:04:19 Healing Made Easy Membership and Final Thoughts

“What if the life you worked so hard to build is also the thing quietly burning you out?” In this episode, Dr. Mariza sits down with Brooke Taylor to unpack the hidden emotional patterns driving burnout, overachievement, perfectionism, and chronic stress in high-performing women. Brooke shares her deeply personal story—from climbing the corporate ladder at Google while battling addiction, burnout, and health issues—to ultimately discovering what she now calls the “Success Wound.” Together, they explore how so many women unconsciously tie their worth, safety, belonging, and identity to achievement… until their body can no longer sustain the pressure. They dive into the emotional roots of over-functioning, the nervous system impact of constantly “doing,” and why midlife often becomes the moment women can no longer outrun themselves. Brooke also shares practical tools to identify your own success wound patterns, regulate your nervous system, reconnect to your true self, and move from manic ambition into aligned ambition. If you've ever felt exhausted despite accomplishing so much… if you've struggled to slow down, feel present, or believe you're enough without constantly proving yourself… this conversation will hit deeply. BROOKE TAYLOR Brooke Taylor is a transformational career coach, speaker, and former Google marketing lead who has helped over 5,000 high-performing women redefine success on their own terms. After experiencing burnout, addiction, and deep emotional reckoning in her own life, Brooke developed the framework she now calls the “Success Wound” to help women break free from overachievement patterns and reconnect to fulfillment, purpose, and self-worth. IN THIS EPISODE What the “Success Wound” actually is—and how it develops Why high-achieving women often tie worthiness to productivity The hidden connection between burnout, perfectionism, and chronic stress How childhood conditioning shapes our relationship with achievement The 5 success wound archetypes: Grinder, Pleaser, Hider, Seeker, and Work Hard/Play Hard Why perimenopause can intensify emotional and nervous system burnout The difference between manic ambition and aligned ambition Practical tools to regulate your nervous system and reconnect to your true self Why healing your success wound is lifelong work—not a quick fix QUOTES“The more that I succeeded, the more love, belonging, and approval I would get.” “We don't rise to the level of our confidence. We fall to the level of our self-worth.” “You are not working from the most powerful part of yourself when you're working from fear.” “There is nothing wrong with your ambition. It's the way your worth became tied to it that needs healing.” RESOURCES MENTIONED Grab Brooke's new book The Success Wound https://amzn.to/3RoWBOC Use code ENERGIZED and get 10% off on your Troscription Order http://troscriptions.com/ENERGIZED Order my new book The Perimenopause Revolution https://peri-revolution.com/ Brooke Taylor Website Brooke Taylor Instagram Brooke Taylor Tiktok RELATED EPISODES  717: “I Don't Feel Like Myself Anymore”: The Mental & Emotional Reality of Perimenopause 741: Estrogen, Gut Health, Mitochondria, and Cardiovascular Health: What Changes In Perimenopause with Dr. Siobhan Mitchel 733: Why We're Still Exhausted in the Age of “Evidence-Based” Everything with Shawn Stevenson 728: Why Brain Fog Isn't Random: The Hormone Shift Behind It

Today, I'm joined by Dr. Taz Bhatia, a trailblazing integrative medicine physician, entrepreneur, and leading voice in women's health and longevity. In our conversation, Dr. Taz opens up about how her personal health challenges as a conventionally-trained MD led her to explore nutrition, Chinese medicine, and Ayurveda, inspiring her to reimagine what it means to truly care for the whole person. We also dive into the work of Countdown, a nonprofit accelerating mitochondrial science and medicine to improve how we prevent and treat disease. If you're interested in women's health, functional medicine, healthy aging, and cellular energy, this episode is packed with valuable insights. Episode Timestamps: Introduction to Longevity Podcast and host ... 00:00:00 Introducing Dr. Taz Bhatia and Countdown's mission ... 00:01:10 Limitations of conventional medicine and time with patients ... 00:08:03 Holistic approach: importance of deep intakes and history ... 00:10:09 Cellular energy and why it matters now ... 00:11:38 Modern lifestyle threats to cellular and mitochondrial health ... 00:12:27 Rising chronic inflammation and age-related diseases ... 00:13:05 Missed opportunities: not measuring or prioritizing cell health ... 00:14:01 Inherited and childhood mitochondrial issues ... 00:15:13 Impact of earlier mitochondrial research on current medicine ... 00:20:12 Manifestations of mitochondrial aging in elderly and kids ... 00:22:15 Women's health: chronic stress, hormone decline, and autoimmunity ... 00:26:40 Risks of hormone treatment without cell health basics ... 00:37:41 Underfunding of women's health research and its clinical impact ... 00:40:34 Mitochondria's direct link to hormone and overall health ... 00:45:02 Countdown: accelerating mitochondrial research and awareness ... 00:46:16 Ovarian aging's role in female longevity ... 00:48:02 Future of medicine: better testing, integration, and support ... 00:54:55 Our Amazing Sponsors: Tro Zzz by Troscriptions – A fast-acting sleep troche that dissolves in your cheek and combines melatonin with compounds like honokiol, adenosine, cordycepin, CBD, CBN, and 5-HTP to support deep, restorative sleep when travel, stress, or late workouts throw things off. Head to troscriptions.com and use code NAT10 for 10% off your first order. Bioregulators by Nature's Marvels - targeted peptides designed to support cellular signaling and renewal across key systems like circadian rhythm, immune function, and vascular health as part of a foundational longevity stack; head to profound-health.com/?Aff=Longevity15 and use code NAT15 for 15% off your first order. O₃RACLE by Wizard Sciences — A daily ozonated oil capsule designed to support immune balance, cellular communication, and antioxidant production without clinics, machines, or complicated routines; learn more at wizardsciences.com and use code NAT15 for 15% off. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Dr. Hoffman continues his conversation with Dr. Corey Schuler, PhD(c), FNP, DC, CNS, and director of medical affairs at Allergy Research Group.

Dr. Corey Schuler, PhD(c), FNP, DC, CNS, and director of medical affairs at Allergy Research Group, details his paper “Energy Allocation Resilience and Endocrine Integration” in the International Journal of Molecular Sciences. He introduces the Energy Allocation System (EAS), which emphasizes how the body allocates energy—not just produces it—and links many symptoms to impaired bioenergetics and resilience. They discuss mitochondria as energy generators and cellular signaling hubs, the integrated stress response and endocrine coordination (HPA axis, thyroid, gonads), and mitohormesis/eustress (exercise, fasting, heat/cold, circadian “zeitgebers”). Schuler explains nuanced testing for fatigue (diurnal cortisol, CGM patterns, thyroid markers including T3/reverse T3) and a case of a perimenopausal woman where oral contraceptives and cortisol dysregulation affected glucose patterns. They cover mitochondrial support (removing obstacles like pollutants/antibiotics, triglycerides, carnitine, dietary fats, micronutrients) and pacing/sequencing lifestyle interventions.

All links here: ⁠https://hunterwilliamshealth.com/linksSS-31 continues to be one of my favorite peptides of all time, and the more data that comes out on it, the more I think every person over 25 has a use case for it.In this masterclass, I'm breaking down everything I know about SS-31. We cover what it actually does at the cellular level, why it's the first FDA-approved mitochondrial peptide, and why it works differently than almost every other peptide out there. No receptor binding. It goes inside your cells, binds to cardiolipin, and stabilizes the structure of your mitochondria.I walk through the three dosing tiers I use with people, my take on cycling, why I run SS-31 before MOTS-c, how to stack it with GLPs, GH peptides, and the healing peptides, and what to actually track when you're on it. I also cover the troubleshooting stuff people ask me about constantly. Why don't I feel anything? Should I cycle? What about the headaches in the first two weeks?If you're a clinician or just researching for yourself, this is the complete user's guide.For entertainment purposes only.Timestamps00:00 Intro01:00 What this masterclass covers03:18 Why SS-31 matters and what makes it different03:46 FDA approval and the Forzenity brand name04:50 Peptide foundations and how SS-31 is made05:52 The SS-31 sequence and the Seto-Schiller naming origin06:40 Mitochondria 101 and why ATP matters07:28 Mitochondrial dysfunction across chronic disease08:34 Cardiolipin, cristae, and Barth syndrome09:34 Why SS-31 is not a direct antioxidant10:46 How SS-31 actually works (the upstream Godfather effect)11:12 Why no receptor means no desensitization13:36 Who SS-31 is for (mid-30s, athletes, post-illness, metabolic dysfunction)14:24 Who should skip it15:34 The three-tier dosing ladder16:54 The FDA-approved 40mg dose and diminishing returns19:08 Dosing by goal (longevity, performance, recovery, healing)19:48 Cycling logic and the 8-12 week framework20:22 When to dose (morning vs night)21:24 What to expect and when (week-by-week timeline)22:20 Why cycle if it doesn't desensitize24:24 SS-31 before MOTS-c (the structural engineer vs operations manager)26:18 Reconstitution and injection technique28:22 What to track (subjective markers and biomarkers)29:18 Stacking with MOTS-c, Humanin, BPC, GH peptides, and GLPs31:28 Stacking for cognition and visceral fat32:26 Troubleshooting "I don't feel anything"33:54 Injection site reactions34:36 When to discontinue and the first-two-week headache window35:52 FAQ (legality, MitoQ comparison, oral routes, intranasal)36:54 Use cases (weight loss, long COVID, athletic performance, TRT, kids)37:54 Research grade vs pharmaceutical cost difference38:22 Future outlook (AMD, sarcopenia, SBT-272, oral bioavailability)40:30 Final thoughts and where SS-31 sits in the broader picture42:20 Closing

You are unknowingly consuming an entire credit card's worth of plastic every single week. It's hiding in your tea bags, your store receipts, and even your $130 workout clothes. And the biological consequences are absolutely terrifying: studies show microplastics are now found in 100% of human testicles, they reduce mitochondrial energy by 35%, and they literally punch holes through your gut lining within 14 days. Uncover what's really going on in your body with advanced biomarker testing for hormones, thyroid, and metabolism— plus a 1-hour consultation with a Senior Health Advisor! → http://mybloodwork.com If you're ready to start feeling like yourself again and balance your hormones, take my free class → http://DrAxeHormoneClass.com Thank you to our sponsors! Sunlighten Sauna: https://get.sunlighten.com/axepodcast Manukora Manuka Honey: https://manukora.com/axe Caraway Home: carawayhome.com/drjoshaxe (Use code DRJOSHAXE) for an exclusive discount Watch The Dr. Josh Axe Show every Monday & Thursday on YouTube: https://www.youtube.com/@drjoshaxe?sub_confirmation=1 Pre-order my NEW BOOK, Heal Your Cells → https://bit.ly/3QJBcQ5

In today's episode, we dive into the “clinical faces of fatigue.” Join Datis Kharrazian as we explore why some individuals never fully recover from illnesses or injuries, the intricate link between mood and brain energy, and why two patients with similar medical conditions like anemia can have vastly different experiences of fatigue.We'll unravel how mitochondrial dysfunctions, both inherited and acquired, lie at the heart of chronic fatigue, depression, fibromyalgia, and other conditions often resistant to simple solutions. You'll discover why bagfuls of supplements aren't enough, and how real recovery requires understanding and addressing the unique bioenergetic roadblocks each patient faces, ranging from oxidative stress and poor sleep to blood sugar imbalances and exposure to environmental toxins.Register for Chronic Fatigue and Pain Syndromes Clinical Strategies and Treatment Applications at https://pages.kharrazianinstitute.com/chronic-fatigue-and-pain-syndromesTo become a Certified Functional Medicine practitioner, visit https://kharrazianinstitute.com/⁠. Try our 7-day free trial, no credit card required. 00:00 Factors affecting mitochondrial function03:55 Optimizing patient bioenergetics basics09:27 Mitochondria and cell evolution12:33 Focus on acquired mitochondrial dysfunctions14:23 Mitochondrial ATP production process20:22 Ketogenic diet and energy pathways21:15 Ketogenic diet for chronic fatigue27:02 Exploring functional medicine resourcesSupport this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

“Perimenopause is more than just hot flashes and mood swings—it's a biological inflection point.” In this solo episode, Dr. Mariza discusses the deeper, often overlooked changes happening during perimenopause and menopause. It's more than a reproductive shift; it's a systemic change affecting the brain, metabolism, hormones, mitochondria, gut health, and more. Dr. Mariza delves into the silent shift that many women experience—feeling exhausted, stressed, and unproductive despite their best efforts. She explains how perimenopause accelerates aging processes, and why early intervention is key to reducing long-term health risks and preserving vitality. This episode focuses on actionable steps you can take to support your body during this critical transition—from stabilizing blood sugar and building muscle to optimizing sleep and protecting your brain. If you've been feeling “off” but can't explain why, this episode is a must-listen. Be sure to tune in! IN THIS EPISODE Why perimenopause is a biological and metabolic inflection point The connection between hormonal fluctuations, mitochondria, and energy How perimenopause accelerates aging and increases risk for chronic diseases Why "just pushing through" is not the solution for midlife women The importance of early intervention for better long-term health outcomes Simple strategies for building energy, optimizing brain function, and protecting your future health How stabilizing blood sugar, improving muscle mass, and prioritizing sleep can reduce inflammation and support resilience QUOTES“Perimenopause is more than just skipped periods or hot flashes. It's a shift in every system of the body.” “You deserve so much better than being told to just survive this season.” “The moment to intervene is now—not when your health has deteriorated.” RESOURCES MENTIONED Order my newest book: The Perimenopause Revolution https://peri-revolution.com/ Use code ENERGIZED and get 10% off on your Troscription Order http://troscriptions.com/ENERGIZED Use code DRMARIZA and get 10% off on your Womeness Order https://www.womaness.com/DRMARIZA Check out the Morning Metabolic Ignition Method for better energy and resilience RELATED EPISODES  744: The Midlife Brain Reset: How to Protect Your Memory, Focus & Mental Sharpness Starting Now 717: “I Don't Feel Like Myself Anymore”: The Mental & Emotional Reality of Perimenopause 728: Why Brain Fog Isn't Random: The Hormone Shift Behind It 741: Estrogen, Gut Health, Mitochondria, and Cardiovascular Health: What Changes In Perimenopause with Dr. Siobhan Mitchel

Why Isn't Everyone Talking About Mitochondria? with Jennifer Scheinman Most people learned the word in 10th-grade biology and never thought about it again. That, argues registered dietitian and longevity expert Jennifer Scheinman, is exactly the problem. In this episode of Why Isn't Everyone Doing This?, Emily Fletcher sits down with Jennifer, a nutritionist with over 25 years of experience and a longevity expert at Timeline, the company behind the clinically studied Urolithin A supplement MitoPure, for a conversation that reframes everything from fatigue to aging to consciousness through the lens of your cells. Jennifer explains how the mitochondria work, why their decline accelerates in your 40s and 60s, and what you can actually do to slow that process. They cover the 12 biological hallmarks of aging, the cellular recycling system (mitophagy) that breaks down over time, why so many people can't produce Urolithin A on their own, and how to evaluate supplements in an industry the FDA doesn't fully regulate. They also connect it all to meditation, to stress, to perimenopause, and to the Greek myth of Persephone and the pomegranate. And at the very end: a fact about mitochondrial DNA that changes the way you think about your mother, your grandmother, and the feminine line you carry. In this episode, they explore: – What mitochondria are, what they do, and why they're more like a CEO than a powerhouse – The cellular recycling process (mitophagy) and why it slows with age – Zombie cells, inflammaging, and the 12 hallmarks of biological aging – Why aging isn't linear — and what the research says about the 40s and 60s – How meditation reduces the inflammation driving cellular decline – Urolithin A: what it is, how your gut should be making it, and why most people's isn't – How to read supplement labels and avoid "fairy dusting" and borrowed science – Timeline's clinical research: what the trials showed and how long results take – The topical MitoPure skincare line and UV-related skin aging – Why mitochondrial DNA is inherited exclusively through the maternal line – Persephone, pomegranates, 108 seeds, and the convergence of myth and molecule Key Moments: 00:00 — The question that opens the episode 03:00 — Mitochondria 101: what they really are 08:15 — Every cell except red blood cells runs on mitochondrial energy 10:00 — Mitophagy: your body's cellular cleanup crew 13:00 — Why aging accelerates in the 40s and again in the 60s 16:00 — Zombie cells and the inflammaging hallmark 19:00 — Meditation's effect on cellular inflammation — the Ziva link 25:00 — Fasting and perimenopause: what the science says for women 29:00 — How to evaluate supplements when labels aren't regulated 35:00 — Urolithin A: gut-made, often missing, and why it matters 40:00 — Why food alone won't get you there (6 cups of pomegranate juice a day) 44:00 — The clinical trials: muscle endurance at 2 months, strength at 4 months 53:00 — Urolithin A + exercise: a likely additive effect 58:00 — How Dr. Gabrielle Lyon first put this on Emily's radar 01:01:00 — The skincare line: bringing MitoPure topically 01:03:00 — Mitochondrial DNA and the matrilineal inheritance 01:05:00 — Persephone, pomegranates, and the place where science meets spirit About Jennifer Scheinman Jennifer Scheinman is a registered dietitian and nutritionist with over 25 years of experience. She is a longevity and nutrition expert at Timeline, the company behind MitoPure — a clinically researched Urolithin A supplement backed by over $50 million in human studies. Her mission is making the science of longevity accessible, practical, and connected to how you actually feel. Follow Jennifer: @jenscheinmanrdLearn more: https://timelinenutrition.com This episode is sponsored by Timeline. Support your mitochondrial health and get 20% off Mitopure at http://timeline.com/ziva. ✨ The Portal is open. If this conversation stirred something in you — around energy, consciousness, and what becomes possible when your body is resourced — you may be ready for what's next. The Portal is Ziva's newest immersive experience, with a VIP weekend for those who want to go further. If you feel the pull, follow it.

Hydrogen water—breakthrough or scam? Osteoporosis fixes; Nattokinase for cardiovascular prevention; Why vitamin D helps a subset of diabetics; When oral vitamin D doesn't work, sublingual D may normalize blood levels; Vitamin D found beneficial for colitis; Why fructose stokes food cravings; Flawed fluoridation study claims no IQ harms to kids.

We tend to think of heart disease, cancer, and Alzheimer's as separate problems. But what if they all stem from the same underlying process? On this episode of The Dr. Hyman Show, I sit down with Dr. Eric Verdin, whose research, including work on compounds like urolithin A, is helping reshape how we think about aging and long-term health. We explore why aging may be the biggest driver of chronic disease and what that means for how you approach your health. Watch the full conversation on YouTube, or listen wherever you get your podcasts. We unpack: • How your immune system becomes both overactive and less effective over time • What chronic inflammation is doing inside your body and how to start bringing it back into balance • Why cellular energy and mitochondrial health are key to repair and recovery • How your microbiome shapes inflammation, immunity, and long-term health • The daily habits that impact longevity most and where people get it wrong This conversation reflects a shift in how we think about health, moving beyond treating disease to understanding what's driving it in the first place. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman's Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Timeline, Seed, BIOptimizers, BON CHARGE, Paleovalley and Big Bold Health. Visit timeline.com/drhyman for 20% off a subscription on top of the new starting price of $79. Go to seed.com/hyman and use code 20HYMAN to get 20% off your first month. Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%. Head to boncharge.com/hyman and use code HYMAN for 15% off. Head to paleovalley.com/hyman to save 15% off your first order today. Go to bigboldhealth.com/drhyman and use code HYMAN15 to save 15% on your first order. (0:00) Biological age vs. cholesterol in heart disease and chronic disease risk (0:50) Introduction of Dr. Eric Verdin and his work (1:23) Sponsor: Brain Shaping Academy (1:51) Sponsor: Mitopure (2:54) Sponsor: Seed (3:48) Welcoming Dr. Eric Verdin and longevity framing (5:42) The geoscience hypothesis and modifying age as a risk factor (8:21) Early-stage interventions in aging and potential for life extension (9:56) Longevity skepticism and practical steps for today (11:20) Mitochondria, inflammation, and hallmarks of aging (17:20) Mitochondrial DNA, inflammation, and immune system aging (22:17) Innate vs. adaptive immunity and immune aging (28:47) Strategies to combat immune aging (33:07) Gut health, inflammation, and foundational elements of longevity medicine (38:20) Social connections, sociogenomics, and cellular energy in aging (46:29) Cellular repair systems and postbiotics (50:33) Sponsor: Paleo Valley (52:34) Sponsor: Big Bold Health (53:23) Urolithin A, immune rejuvenation, and longevity interventions (59:08) Longevity and functional medicine approaches (1:02:27) Big data, AI, and the evolution of medicine (1:04:26) Microbiome, diet, and gut health (1:06:14) Measuring biological age and biological clocks (1:09:37) Future of health monitoring and closing remarks