MediCom Oncology Clinical Pearls Podcasts

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MediCom Oncology Clinical Pearl Podcasts provide practical, evidence-based recommendations on real-world issues in the clinical setting, in under three minutes. Leading experts and academic faculty from top research and practice institutions provide guidance to community-based healthcare providers,…

MediCom Oncology


    • Oct 26, 2018 LATEST EPISODE
    • infrequent NEW EPISODES
    • 3m AVG DURATION
    • 53 EPISODES


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    Latest episodes from MediCom Oncology Clinical Pearls Podcasts

    Third-generation FLT3 inhibitors in clinical development

    Play Episode Listen Later Oct 26, 2018 2:42


    Dr. Perl provides a brief summary of what is on the horizon for FLT3 inhibitors in AML.

    CAR T case study in acute myeloid leukemia

    Play Episode Listen Later Oct 5, 2018 5:49


    Dr. Sallman describes a patient case demonstrating promise in the further study and potential use of CAR T-cell therapy for patients with AML.

    Key considerations when prescribing midostaurin with a strong CYP3A4 inhibi

    Play Episode Listen Later Oct 5, 2018 2:23


    Dr. Perl gives guidance on providing optimal patient therapy when prescribing midostaurin with a strong CYP3A4 inhibitor.

    How to proceed with a patient who presents with idiopathic cytopenia of undetermined significance

    Play Episode Listen Later Mar 20, 2018 3:58


    In this audio activity, Dr. Goldberg describes his approach to patients with idiopathic or clonal cytopenias of undetermined significance (ICUS and CCUS).

    When to consider iron chelation therapy for a transplant-eligible patient

    Play Episode Listen Later Mar 20, 2018 3:56


    Listen as Dr. Goldberg explains his approach to iron chelation therapy in patients who are, or may be within the next 5-10 years, eligible for transplant.

    53-year-old woman presenting with severe fatigue and bruising

    Play Episode Listen Later Mar 20, 2018 3:58


    Hematopathologist Dr. Khoury presents a case snapshot showing the complexities of diagnosing AML, describing the importance of morphology, flow cytometry, cytogenetics, and molecular diagnostics.

    New subcategories of pancreatic cancer allow for a biomarker-driven approach to therapy

    Play Episode Listen Later Jan 5, 2018 4:00


    Dr. O'Reilly discusses the new subcategories of pancreatic cancer that have emerged, and which are laying the groundwork for a biomarker-driven approach to therapy.

    What are the unique aspects of pancreas cancer that lead to the development of novel therapeutics?

    Play Episode Listen Later Jan 5, 2018 2:40


    Dr. O'Reilly discusses the unique pathophysiology of pancreas cancer that must be considered in the development of novel therapeutics.

    Predictors of response to lenalidomide in a non-del(5q) MDS patient

    Play Episode Listen Later Jan 5, 2018 3:03


    Listen as Dr. Goldberg discusses, in just under two minutes, the predictors of response to lenalidomide in a non-del(5q) MDS patient.

    What are the pros and cons of radiation therapy?

    Play Episode Listen Later Dec 21, 2017 2:29


    Listen as Dr. Matasar discusses the pros and cons of radiation therapy, and who should be offered this therapy.

    What defines high-quality survivorship care for patients treated for classical Hodgkin lymphoma?

    Play Episode Listen Later Nov 30, 2017 3:01


    Listen as Dr. Matasar discusses survivorship care for patients who have been treated for classical Hodgkin lymphoma, including late effects of treatment.

    Second primary malignancies associated with lenalidomide maintenance

    Play Episode Listen Later Nov 30, 2017 2:53


    Dr. Jacob Laubach discusses second primary malignancies associated with lenalidomide maintenance in the transplant and post-transplant setting.

    Impact of consolidation therapy in patients post-transplant

    Play Episode Listen Later Nov 30, 2017 3:09


    Dr. Laubach discusses the impact of consolidation therapy in patients post-transplant, referencing results of the CTN StaMINA trial.

    Bortezomib as an alternate strategy for maintenance therapy.

    Play Episode Listen Later Oct 23, 2017 2:32


    Dr. Jacob Laubach discusses bortezomib as an alternate strategy to lenalidomide for maintenance therapy in patients with multiple myeloma.

    What may be the future role for brentuximab vedotin in newly diagnosed Hodgkin lymphoma?

    Play Episode Listen Later Oct 23, 2017 2:35


    Listen as Dr. Matasar discusses the future role of brentuximab vedotin in patients with newly diagnosed classical Hodgkin lymphoma.

    Has MRD testing become a standard of care in multiple myeloma?

    Play Episode Listen Later Oct 23, 2017 3:22


    Dr. Ruben Niesvizky discusses MRD testing and how it has become a standard of care in multiple myeloma, as well as future directions in MRD testing that will improve outcomes in these patients.

    The Precision Promise [SM] Initiative: What is it designed to achieve?

    Play Episode Listen Later Sep 27, 2017 4:32


    Dr. O'Reilly provides an insightful overview of how the emerging use of precision medicine and the Precision Promise [SM] initiative will impact the new drug approval process in pancreatic cancer.

    Enasidenib in mutant-IDH2 R/R AML: Results of a phase 1 dose-escalation and expansion study

    Play Episode Listen Later Sep 27, 2017 8:26


    Dr. Eytan Stein provides a brief update on phase 1 arms of a trial studying the effectiveness of enasidenib in patients with relapsed and refractory AML and an IDH2 mutation.

    What are the optimal imaging methods to determine extent of bone disease in newly diagnosed MM?

    Play Episode Listen Later Sep 27, 2017 3:18


    Dr. Ruben Niesvizky discusses newer approaches for imaging in patients who have multiple myeloma with bone disease, including the benefits of combining modalities such MRI and PET scan.

    The standard of care for patients receiving lenalidomide or thalidomide who are at high risk for VTE

    Play Episode Listen Later Sep 27, 2017 3:36


    Dr. Ruben Niesvizky discusses clinical approaches to managing the risk of developing VTE in myeloma patients receiving immunomodulating agents such as lenalidomide or thalidomide.

    How do I dose daratumumab, lenalidomide and dexamethasone in the combination regimen?

    Play Episode Listen Later Sep 27, 2017 1:59


    In under two minutes, Dr. Carol Ann Huff will discuss how to dose daratumumab in conjunction with lenalidomide and dexamethasone in patients with multiple myeloma.

    Is there a connection between pancreatic cancer and new-onset diabetes?

    Play Episode Listen Later Aug 18, 2017 8:26


    Dr. Anil Rustgi discusses a clinical prediction model to assess risk for pancreatic cancer among patients with new-onset diabetes.

    CPX versus 7 and 3 conventional chemotherapy in older adults with AML

    Play Episode Listen Later Aug 18, 2017 3:16


    Dr. Stuart Goldberg briefly summarizes updates on CPX-351, a liposomal form of cytarabine and daunorubicin that allows for office infusion vs. standard consolidation requiring hospitalization.

    How long should I be infusing carfilzomib intravenously?

    Play Episode Listen Later Aug 18, 2017 2:55


    Listen as Dr. Huff discusses the infusion duration for carfilzomib in patients with multiple myeloma.

    What is the current status of immunotherapy in pancreatic cancer?

    Play Episode Listen Later Aug 2, 2017 4:37


    Listen as Dr. O'Reilly discusses the the current status of immunotherapy in pancreatic cancer.

    Measuring Frailty in Patients Being Treated for Multiple Myeloma

    Play Episode Listen Later Aug 2, 2017 1:49


    Listen for just under two minutes as Dr. Harvey explains measuring frailty in patients being treated for multiple myeloma.

    Differentiation syndrome associated with enasidenib, a selective inhibitor of mutant IDH2

    Play Episode Listen Later Aug 2, 2017 4:04


    Dr. Eytan Stein provides a brief update on patients experiencing differentiation syndrome in a larger enasidenib trial, detailing the creation of a Differentiation Syndrome Review Committee.

    How do I dose daratumumab, bortezomib and dexamethasone in the combination regimen?

    Play Episode Listen Later Aug 2, 2017 3:17


    Listen as Dr. Carol Ann Huff discusses how to dose daratumumab, bortezomib and dexamethasone in the combination regimen.

    Update on the CALGB-100104 (Alliance) randomized trial

    Play Episode Listen Later Aug 2, 2017 3:26


    Listen as Dr. Philip McCarthy provides an update on the CALGB-100104 (Alliance) randomized trial.

    How does the safety profile of the new and emerging anti-PD 1 antibodies differ from chemotherapy?

    Play Episode Listen Later Aug 2, 2017 1:55


    Listen as Dr. Alison Moskowitz discusses the difference between the safety profile of the new and emerging anti-PD-1 antibodies and chemotherapy.

    How does the safety profile of the new and emerging anti-PD 1 antibodies differ from chemotherapy?

    Play Episode Listen Later Jul 12, 2017 1:55


    Listen as Dr. Alison Moskowitz discusses the safety profile of the new and emerging anti-PD1 antibodies and how this differs from traditional chemotherapy in just under two minutes.

    ELOQUENT-2 updates represent the longest median FU of an immuno-oncology agent in MM

    Play Episode Listen Later Jul 12, 2017 1:43


    Dr. Sagar Lonial provides a brief update on the ELOQUENT-2 phase 3 trial and how it continues to demonstrate a benefit in terms of progression-free survival.

    Optimal Pre-medication Strategy for Daratumumab

    Play Episode Listen Later Jul 12, 2017 2:09


    Listen for just under two minutes as Dr. Harvey discusses optimal pre-medications for daratumumab, including H1 antagonists.

    Rash Management for Patients Taking IRd (Ixazomib-Lenalidomide-Dexamethasone)

    Play Episode Listen Later Jun 29, 2017 1:28


    Listen as Dr. Harvey will discuss rash management for patients taking IRd.

    What is the appropriate management for severe hypercalcemia?

    Play Episode Listen Later Jun 29, 2017 2:31


    Listen as Dr. Niesvizky explains the appropriate management for severe hypercalcemia.

    What is the most common cause of renal failure in newly diagnosed patients with multiple myeloma?

    Play Episode Listen Later Jun 29, 2017 1:54


    Listen as Dr. Niesvizky discusses the most common cause of renal failure in newly diagnosed patients with MM.

    Standard dosing and delivery of Nal-IRI + 5-FU/LV

    Play Episode Listen Later Jun 29, 2017 2:21


    Listen as Dr. Wang-Gillam discusses the standard dosing and delivery of Nal-IRI + 5-FU/LV.

    How important is the availability of supportive care when considering transplant in older patients?

    Play Episode Listen Later May 15, 2017 2:26


    Listen as Dr. Ritchie discusses the importance of available supportive care when considering transplant in older patients with MDS.

    Is the AE profile of BV the same or different from traditional monoclonal antibody therapies?

    Play Episode Listen Later May 15, 2017 2:09


    Listen as Dr. Moskowitz discusses the AE profile of BV and traditional monoclonal antibody therapies.

    When do you need to do a bone marrow biopsy in the management or assessment of multiple myeloma?

    Play Episode Listen Later May 15, 2017 2:37


    Listen as Dr. Richter discusses when you need to do a bone marrow biopsy in the management or assessment of multiple myeloma.

    What are some of the more common adverse reactions associated with brentuximab vedotin?

    Play Episode Listen Later Apr 28, 2017 2:49


    Listen as Dr. Moskowitz discusses the more common adverse reactions associated with brentuximab vedotin and how they are most often managed.

    What are the different technologies used to assess cytogenetic risk status?

    Play Episode Listen Later Apr 28, 2017 2:17


    Listen as Dr. Richter will discuss the different technologies used to assess cytogenetic risk status in your myeloma patient.

    What is meant by the term high-risk myeloma?

    Play Episode Listen Later Apr 28, 2017 2:30


    Listen as Dr. Richter will discuss the meaning of high-risk myeloma.

    Standard dosing and delivery of FOLFIRINOX

    Play Episode Listen Later Apr 28, 2017 2:24


    Listen as Dr. Andrea Wang-Gillam explains standard dosing and delivery of FOLFIRNOX in patients with pancreatic cancer.

    The new FDA approval of pembrolizumab for cHL

    Play Episode Listen Later Mar 23, 2017 4:36


    Listen as Dr. Anas Younes covers the new FDA approval of pembrolizumab for patients with cHL.

    Standard dosing and delivery of gemcitabine/nab-paclitaxel

    Play Episode Listen Later Mar 23, 2017 2:22


    Listen as Dr. Andrea Wang-Gillam explains standard dosing and delivery of gemcitabine/nab-paclitaxel in patients with pancreatic cancer.

    How do I diagnose chronic myelomonocytic leukemia (CMML)?

    Play Episode Listen Later Mar 9, 2017 3:35


    Listen as Dr. Rami Komrokji explains how to diagnose chronic myelomonocytic leukemia (CMML).

    What tests should I obtain upfront at the time of MDS diagnosis?

    Play Episode Listen Later Feb 23, 2017 2:58


    Listen as Dr. Rami Komrokji discusses what tests to obtain upfront at the time of MDS diagnosis.

    How do I manage diarrhea in my patients taking ixazomib?

    Play Episode Listen Later Feb 7, 2017 1:22


    Listen as Dr. Donald Harvey explains how to manage diarrhea in patients taking ixazomib.

    What prophylactic antithrombotic agents are safe to use with lenalidomide?

    Play Episode Listen Later Feb 7, 2017 1:22


    Listen as Dr. Donald Harvey explains which prophylactic antithrombotic agents are safe to use with lenalidomide.

    How do I manage renal dysfunction in my patient who is taking lenalidomide?

    Play Episode Listen Later Feb 7, 2017 1:22


    Listen as Dr. Donald Harvey explains how he manages renal dysfunction in a patient who is taking lenalidomide.

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