Podcasts about Frailty

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Best podcasts about Frailty

Show all podcasts related to frailty

Latest podcast episodes about Frailty

The Brian Craig Show
Spencer Pratt Latest Update

The Brian Craig Show

Play Episode Listen Later Jun 9, 2026 62:50


Spencer Pratt Latest Update Selena Studio Art https://www.etsy.com/shop/selenastudioart/?etsrc=sdt Jupiter Joe YouTube Channel Radio Show and Podcast https://www.youtube.com/@jupiterjoemoneyshow/videos https://www.jupiterjoe.com TV Insiders https://open.spotify.com/show/6AtTqqfoJNj1yHYLNCz80c?si=d7287583b8484d7b&nd=1&dlsi=801babeb79b847f4 The One https://www.amazon.com/dp/B0H321BQ4N?ref_=cm_sw_r_ffobk_cp_ud_dp_6H1T3P8D9RS159N6JD2T&bestFormat=true A Chicken was There Celebrate America https://www.amazon.com/dp/B0H1MQL1W6?ref_=cm_sw_r_ffobk_cp_ud_dp_F0E0XDY35X7VVDTM5EDX&bestFormat=true Frailty of Fact https://www.amazon.com/dp/B0G6V5TXSS?ref_=cm_sw_r_ffobk_cp_ud_dp_Q1A70AGYH7W157EN71BW&bestFormat=true Kindred https://www.amazon.com/dp/B0GQJ7CR3T?ref_=cm_sw_r_ffobk_cp_ud_dp_CB4014ARFP9K4EFCAVQ8&bestFormat=true Save up to 80% off Top MyPillow Prodcuts with our Promo Code KANE at Checkout https://www.mypillow.com/kane Thank you to our Top Patreon Supporters! Andrew and Connie, Cristine, ETW, Chuck, Pamela, Nick, Wesley,  Heather, David, Maria in Texas, Alice, LeeZep, Shawana, George, Brandon, John S, Frank, Dale,David,Laura B, Rob L. SFjr. Irene Support the show and become a Patreon Supporter! https://www.patreon.com/realbriancraigshow https://briancraigshow.com LaPorta Roofing  https://www.laportaroofing.com    

Holy Redeemer Podcasts
Fragility, Frailty and Mobility - Part 1 - Ageing Gracefully - Episode 27

Holy Redeemer Podcasts

Play Episode Listen Later Jun 8, 2026 37:46


As we age, fragility, frailty, and mobility become crucial aspects of our well-being. Understanding these challenges helps us navigate ageing with dignity, strength, and independence. In this insightful episode of Ageing Gracefully, Fr. Juventius Andrade hosts a discussion with two distinguished experts:

Holy Redeemer Podcasts
Fragility, Frailty and Mobility - Part 2 - Ageing Gracefully - Episode 28

Holy Redeemer Podcasts

Play Episode Listen Later Jun 8, 2026 44:07


In Part 2, we dive deeper into the themes of fragility, frailty, and mobility, exploring how they intersect with the aging process. This episode features insightful discussions with experts Fr. Juventius Andrade, Dr. Pratibha, and Dr. Ravindran. Together, they shed light on the physical and emotional challenges that arise as we age, offering advice on maintaining strength, resilience, and independence. From strategies to improve mobility to understanding the nuances of frailty, this episode is a thoughtful resource for those seeking to age gracefully, with dignity and health in mind.

Holy Redeemer Podcasts
Fragility, Frailty and Mobility - Part 3 - Ageing Gracefully - Episode 29

Holy Redeemer Podcasts

Play Episode Listen Later Jun 8, 2026 51:00


In this insightful episode of Ageing Gracefully, we continue our conversation on the challenges and realities of ageing, focusing on fragility, frailty, and mobility. Fr. Juventius Andrade, along with esteemed medical experts Dr. Pratibha and Dr. Ravindran, discuss the physical and emotional aspects of ageing, addressing key concerns such as maintaining strength, preventing falls, and enhancing mobility in later years.With a compassionate and practical approach, our panel explores strategies to promote independence, resilience, and quality of life as we age. Whether you're a senior looking for guidance, a caregiver supporting a loved one, or simply interested in understanding the ageing process, this episode offers valuable insights and encouragement to embrace ageing with grace and dignity.Join us for this engaging discussion, as we continue to explore how faith, medicine, and mindful living can help navigate the golden years with wisdom and hope.

The Brian Craig Show
Why Is Candace Owens in Russia The Real Story Behind the Trip

The Brian Craig Show

Play Episode Listen Later Jun 7, 2026 51:14


Why Candace Owens is in Russia http://americanfinancing.net/craig Selena Studio Art https://www.etsy.com/shop/selenastudioart/?etsrc=sdt Jupiter Joe YouTube Channel Radio Show and Podcast https://www.youtube.com/@jupiterjoemoneyshow/videos https://www.jupiterjoe.com TV Insiders https://open.spotify.com/show/6AtTqqfoJNj1yHYLNCz80c?si=d7287583b8484d7b&nd=1&dlsi=801babeb79b847f4 The One https://www.amazon.com/dp/B0H321BQ4N?ref_=cm_sw_r_ffobk_cp_ud_dp_6H1T3P8D9RS159N6JD2T&bestFormat=true A Chicken was There Celebrate America https://www.amazon.com/dp/B0H1MQL1W6?ref_=cm_sw_r_ffobk_cp_ud_dp_F0E0XDY35X7VVDTM5EDX&bestFormat=true Frailty of Fact https://www.amazon.com/dp/B0G6V5TXSS?ref_=cm_sw_r_ffobk_cp_ud_dp_Q1A70AGYH7W157EN71BW&bestFormat=true Kindred https://www.amazon.com/dp/B0GQJ7CR3T?ref_=cm_sw_r_ffobk_cp_ud_dp_CB4014ARFP9K4EFCAVQ8&bestFormat=true Save up to 80% off Top MyPillow Prodcuts with our Promo Code KANE at Checkout https://www.mypillow.com/kane Thank you to our Top Patreon Supporters! Andrew and Connie, Cristine, ETW, Chuck, Pamela, Nick, Wesley,  Heather, David, Maria in Texas, Alice, LeeZep, Shawana, George, Brandon, John S, Frank, Dale,David,Laura B, Rob L. SFjr. Irene Support the show and become a Patreon Supporter! https://www.patreon.com/realbriancraigshow https://briancraigshow.com LaPorta Roofing  https://www.laportaroofing.com    

The Brian Craig Show
Who Is Graham Platner The True History

The Brian Craig Show

Play Episode Listen Later Jun 6, 2026 60:29


The True History of Graham Platner http://americanfinancing.net/craig Selena Studio Art https://www.etsy.com/shop/selenastudioart/?etsrc=sdt Jupiter Joe YouTube Channel Radio Show and Podcast https://www.youtube.com/@jupiterjoemoneyshow/videos https://www.jupiterjoe.com TV Insiders https://open.spotify.com/show/6AtTqqfoJNj1yHYLNCz80c?si=d7287583b8484d7b&nd=1&dlsi=801babeb79b847f4 The One https://www.amazon.com/dp/B0H321BQ4N?ref_=cm_sw_r_ffobk_cp_ud_dp_6H1T3P8D9RS159N6JD2T&bestFormat=true A Chicken was There Celebrate America https://www.amazon.com/dp/B0H1MQL1W6?ref_=cm_sw_r_ffobk_cp_ud_dp_F0E0XDY35X7VVDTM5EDX&bestFormat=true Frailty of Fact https://www.amazon.com/dp/B0G6V5TXSS?ref_=cm_sw_r_ffobk_cp_ud_dp_Q1A70AGYH7W157EN71BW&bestFormat=true Kindred https://www.amazon.com/dp/B0GQJ7CR3T?ref_=cm_sw_r_ffobk_cp_ud_dp_CB4014ARFP9K4EFCAVQ8&bestFormat=true Save up to 80% off Top MyPillow Prodcuts with our Promo Code KANE at Checkout https://www.mypillow.com/kane Thank you to our Top Patreon Supporters! Andrew and Connie, Cristine, ETW, Chuck, Pamela, Nick, Wesley,  Heather, David, Maria in Texas, Alice, LeeZep, Shawana, George, Brandon, John S, Frank, Dale,David,Laura B, Rob L. SFjr. Irene Support the show and become a Patreon Supporter! https://www.patreon.com/realbriancraigshow https://briancraigshow.com LaPorta Roofing  https://www.laportaroofing.com    

Intelligent Medicine
Leyla Weighs In: Building Strength Against Frailty--Key to Independent Living

Intelligent Medicine

Play Episode Listen Later Jun 5, 2026 23:32


Nutritionist Leyla Muedin discusses research showing simple strength tests—grip strength and a five-rep sit-to-stand chair test—predict longevity in older women. In a University at Buffalo study of over 5,000 women ages 63–99 followed for eight years, stronger grip and faster chair-stand times were linked to lower mortality; every additional 7 kg of grip strength corresponded to a 12% reduction in death risk, and faster chair-stands were also associated with improved survival, even after adjusting for activity, cardiovascular fitness, and inflammation. She emphasizes prioritizing muscle-strengthening alongside aerobic exercise and suggests accessible resistance options (weights, bodyweight moves, or household items) with professional guidance as needed. She then cites UK Biobank data linking long-term statin use to declines in grip strength and appendicular lean mass, urging discussion with physicians and added vigilance, especially for those also using GLP-1 drugs that may reduce protein intake and muscle mass.

eGPlearning Podblast
General Practice Update - Defunding the BMA GPCE, collective action month 2, and is a hyperfocus on access undermining frailty managment?

eGPlearning Podblast

Play Episode Listen Later Jun 4, 2026 46:19


Contact us and share your opinionIn this episode…GP Collective Action Month 2 - Medication Optimisation SoftwareA “hyper focus” on GP access at the expense of frailty management is discussed at the Public Accounts Committee at WestminsterGPCE Committee funding at risk as GPDF debate motion to cease funding in favour of an alternative  way to secure a “Plan B” dentistry like model for General PracticeBoost your triage skills with our dynamic 5-session live webinar course, tailored for primary care clinicians. Led by Dr. Gandalf and Dr. Ed Pooley, this comprehensive training covers all facets of remote patient triage—digital, on-call, and more. Gain practical knowledge, exclusive tips, and direct access to our experts through open Q&A sessions. Elevate your ability to manage primary care challenges effec Join Dr Mike as he shares how to get started and fly using EMIS to make your life easier with this clinical systembit.ly/EMIScourse

Jesus Calling: Stories of Faith
Life's Frailty and God's Peace: Amy Grant and Andrew Osenga

Jesus Calling: Stories of Faith

Play Episode Listen Later May 28, 2026 34:17 Transcription Available


This week, we’re honored to welcome back a dear friend of the show—the iconic artist, singer, and GRAMMY winner Amy Grant. Amy joins us to share her heart about her first album of original material in thirteen years, the deeply personal project titled “The Me That Remains.” In this moving interview, Amy opens up about the profound life events that inspired her new music—navigating the tender journey of aging and caring for her parents at the end of their lives, her ongoing recovery from a serious bike accident, and the enduring joy of creating music that she feels grateful to share with the world. Later in the episode, we’ll hear from Andrew Osenga, a Nashville-based musician, writer, and podcaster. Andrew spent years trapped in the tension between his private doubts and the crushing expectation of performing as a Christian artist. Growing up, image was everything, and he struggled under the pressure to appear “put-together”—even when he felt broken inside. It took devastating loss—including his home flooding, displacing his family, and his wife’s grueling cancer journey—for him to finally break free from performance-driven faith. Links, Products, and Resources Mentioned: Jesus Calling Podcast Jesus Calling Jesus Always Jesus Listens Past interview: Diane Chew Upcoming interview: Annie Bosko Amy Grant The Me That Remains - Album by Amy Grant The Book of Forgiving - Book by Desmond Tutu and Mpho Tutu The 6th Of January (Yasgur's Farm) - Song by Amy Grant Andrew Osenga How to Remember: Forgotten Pathways to an Authentic Faith - Book by Andrew Osenga Caedmon’s Call Young Life Interview Quotes: “Don't ever be afraid to speak the truth of what is right now.” - Amy Grant “Life is happening to all of us all the time, and we have to be gentle with ourselves and gentle with each other.” - Amy Grant “I feel like the arts are good medicine for everybody.” - Amy Grant “We are all part of humanity and we all experience good, hard and unresolved unrest; how do we sit in it and find our way forward?” - Amy Grant “When [accidents or illnesses] come, you need people in your life to remind you what matters: you are loved by God, and if you’re still breathing, the adventure continues.” - Amy Grant “Jesus doesn’t want us to pretend. He wants us to be the people He created. He doesn’t love a fake image of me. He loves me.” - Andrew Osenga “There have been a number of experiences in my life that have helped redirect me towards a more quiet and grounded way of being with God, moving from performance towards presence.” - Andrew Osenga “The wonderful thing is Jesus doesn’t meet us in our perfection, He meets us in our suffering. Jesus is introduced to us in the Bible as a man of sorrows. And so, it’s not that we have to stay there all the time, knowing that is a part of our story. Being able to be honest about that allows us this freedom to be people of joy rather than having to sort of put on a happy face.” - Andrew Osenga “We can say that we can hold suffering and joy in both hands at the same time, and I think those are the people that we’re drawn to. And that’s when we can start to speak with an authentic voice. That takes time to learn how to do that, and that takes, honestly, walking through seasons of both suffering and joy to be able to learn how to do that.” - Andrew Osenga “We live in a culture that prizes things like novelty, speed, and constant reinvention. I think these practices like lament, confession, shared prayer, and silence can be a form of resistance, pushing back against this speed, the hectic life, against the doom scroll.” - Andrew Osenga ________________________ Enjoy watching these additional videos from Jesus Calling YouTube channel! Audio Episodes: https://bit.ly/3zvjbK7 Bonus Podcasts: https://bit.ly/3vfLlGw Jesus Listens: Stories of Prayer: https://bit.ly/3Sd0a6C Peace for Everyday Life: https://bit.ly/3zzwFoj Peace in Uncertain Times: https://bit.ly/3cHfB6u What’s Good? https://bit.ly/3vc2cKj Enneagram: https://bit.ly/3hzRCCY ________________________ Connect with Jesus Calling Instagram Facebook Twitter Pinterest YouTube Website TikTok Discover more Christian podcasts at lifeaudio.com and inquire about advertising opportunities at lifeaudio.com/contact-us.

Clinical Update
Tackling dementia underdiagnosis and supporting patients and families, with Dr Alistair Robertson

Clinical Update

Play Episode Listen Later May 27, 2026 37:07


Around a third of patients with dementia remain undiagnosed. Dr Alistair Robertson, a GP with an extended role in frailty, provides insights for GPs and other primary care professionals on how they can address  underdiagnosis and provide support for patients and their families. He covers signs and symptoms to look out for, assessments to conduct, the role of drug treatments, and the benefits of honest conversations with patients and families.Educational objectivesAfter listening to this podcast, healthcare professionals should be better able to:Consider the number of patients in their practice who may have undiagnosed dementiaReflect on differential diagnoses and how to take a good historyRecall key signs and symptoms to look out for and how these may differ in different types of dementiaUnderstand the role of cognitive assessment tools and how to use themReview current drug treatments and their effectivenessExplore how to address polypharmacyUnderstand the importance of early, honest conversations with patients and familiesYou can access the website version of this podcast, along with a list of key learning points and downloadable notes written by Dr Robertson, on MIMS Learning. MIMS Learning offers hundreds of hours of CPD for healthcare professionals, along with a handy CPD organiser and note-taking for appraisal.Please note: this podcast is presented by medical editors and discusses educational content written or presented by doctors, nurses and other healthcare professionals on the MIMS Learning website and at live events.MIMS LearningRegister for a FREE accountRelated resources from MIMS Learning and MIMSPractical advice for GPs on dementia document created by Dr Alistair Robertson.Frailty: clinical reviewGuidance update: SIGN guidelines for support of people with dementia and their carersPolypharmacy in a patient with dementia: nursing home case studyAnticholinergic cognitive burden (ACB) scores for commonly used drugs Hosted on Acast. See acast.com/privacy for more information.

eGPlearning Podblast
New Health Secretary, NHS modernisation bill and LMC UK conference update

eGPlearning Podblast

Play Episode Listen Later May 21, 2026 64:24


Contact us and share your opinionVote for your winner here: https://us22.list-manage.com/survey?u...Join the TPP conference: https://mailchi.mp/tpp-uk/tpp-systmon...Join DrGandalf and Team GP in primary care as they show off how to use TPP SystmOne to innovate care and support Neighbourhoods with the chance to win £1000 for each award.00:00 TPP Awards intro01:13 Previous Award WINNERS02:30 Meet the Nominees04:16 CLAS by Countesthorpe Health Centre15:56 Majic NAV by Kings Medical Practice27:30 Cancer workflow by Parkside Medical Centre38:29 INT with Spen Health PCN48:35 Frailty and CGA by Pathfields Medical Group56:40 Vote and Major newsBoost your triage skills with our dynamic 5-session live webinar course, tailored for primary care clinicians. Led by Dr. Gandalf and Dr. Ed Pooley, this comprehensive training covers all facets of remote patient triage—digital, on-call, and more. Gain practical knowledge, exclusive tips, and direct access to our experts through open Q&A sessions. Elevate your ability to manage primary care challenges effec Join Dr Mike as he shares how to get started and fly using EMIS to make your life easier with this clinical systembit.ly/EMIScourse

The Oncology Nursing Podcast
Episode 415: Myelodysplastic Syndrome Treatment Considerations for Oncology Nurses

The Oncology Nursing Podcast

Play Episode Listen Later May 15, 2026 30:53


"We want to make sure that we discuss the details of the treatment and what treatments there are, whether it's an oral drug, whether it's a subcutaneous injection or an IV injection, [the patient's] potential for responding, whether this treatment is curative or supportive, and what the number of visits are. All of those different pieces of information that go into the decision-making process are really important," ONS member Sara Tinsley-Vance, PhD, APRN, AOCN®, nurse practitioner and quality-of-life researcher at Moffitt Cancer Center in Tampa, FL, told Lenise Taylor, MN, RN, AOCNS®, TCTCN™, oncology clinical specialist at ONS, during a conversation about myelodysplastic syndrome (MDS) treatment considerations. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.5 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by May 15, 2027. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge about the treatment considerations for MDS. Episode Notes  Complete this evaluation for free NCPD.  ONS Podcast™ episodes: Episode 411: An Overview of Myelodysplastic Syndrome for Oncology Nurses Episode 256: Cancer Symptom Management Basics: Hematologic Complications ONS Voice articles: FDA Approves Luspatercept-Aamt for Anemia in Adults With MDS Infection Prevention for Oncology Nurses Manage Cancer-Associated Anemia With Erythropoietin-Stimulating Agents Whole-Genome Sequencing May Guide Treatment Choices for AML and MDS Clinical Journal of Oncology Nursing articles:  Reducing Effects of Hospital-Associated Deconditioning in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation Resilience in Older Adults Diagnosed With Cancer and Receiving Chemotherapy Targeted Drug Therapies: Beyond Blood Counts and Chemistries Oncology Nursing Forum article: Frailty in Patients With Hematologic Malignancies and Those Undergoing Transplantation: A Scoping Review ONS books:  BMTCN™ Certification Review Manual (second edition) Hematopoietic Stem Cell Transplantation: A Manual for Nursing Practice (third edition) ONS course: Hematopoietic Stem Cell Transplantation™ ONS Learning Library: Hematology, Cellular Therapy, and Stem Cell Transplantation ONS Symptom Intervention resources: Prevention of Infection: General Prevention of Infection: Transplant Aplastic Anemia and MDS International Foundation: MDS Drugs and Treatments Blood Cancer United: MDS Treatment HealthTree Foundation Myelodysplastic Syndromes Foundation To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "The goals that I try to consolidate to make sure they're consistent with the patient's goals are to improve their counts, especially the anemia or cytopenias. If they're getting blood transfusions, we want to reduce the number of transfusions that they receive because we know that's linked to reduced overall survival, and it really impacts quality of life. ... And then for high-risk patients, it's a more serious discussion because we know that they are the ones who can progress to acute myeloid leukemia (AML). And we're trying to delay progression to AML. That means we're trying to improve their survival and we're also trying to manage their cytopenias and decrease their infection risk." TS 2:28 "If we look at approvals for low-risk disease and high-risk disease, those were really made based on the Revised International Prognostic Scoring System (IPSS-R) and sometimes the International Prognostic Scoring System (IPSS). Under those classification systems, when we think of lower-risk MDS, we think of patients who are primarily anemic but don't have increased blasts in their bone marrow. ... For higher-risk MDS, we want to have that discussion with those patients because their life expectancy is much shorter than patients with lower-risk MDS. We want to see if hematopoietic stem cell transplant would be something that they would be interested in if they don't have a lot of comorbidities and are relatively healthy." TS 11:41 "There are a lot of things to consider—[patients'] blood counts, comorbidities, whether they're frail, and what their goals are. There are some patients where there's no way they would want to go through transplant. And some patients want to be cured, so it just depends on your patient." TS 14:22 "I think of hematopoietic allogeneic transplants as a treatment for more of the patients with higher-risk MDS. ... With the Molecular International Prognostic Scoring System (IPSS-M), a patient can have pretty good blood counts and not have increased blasts in the bone marrow. You could send them for a transplant referral upfront without having to give them additional treatment. ... There is a recent publication that said if a patient doesn't have more than 10% blast, you could refer to transplant as a first option. ... Also, if you had a lower-risk patient who is relatively young and doesn't have any other treatment options, this would also be a patient that you could refer to transplant to see if we could care for them, and then they wouldn't have to be getting transfused all the time." TS 21:12 "I think that we often think low-risk, no treatment needed, but it depends on the person. They often need ongoing supportive care to manage their symptoms even if they're not getting treatment. And just because we're not treating them, active observation, bringing them in to see how they're doing, if they've had infections, if their blood counts are changing, that is paying attention to them and doing something. Just because they're low-risk doesn't mean they don't need anything and we can just schedule for a one-year follow-up." TS 26:30

LTC University Podcast
A Nurse Practitioner's Field Guide to Whole-Person Care — with Jaclyn Taylor, PART 1

LTC University Podcast

Play Episode Listen Later May 15, 2026 26:42


What if every "non-compliant" patient was actually a signal that the system isn't working for them? In this episode, Jamie sits down with Jaclyn Taylor, Clinical Strategy Director at Your Health and a nurse practitioner who started her career as a home-based provider in 2020 — thrown straight into the fire of COVID, isolated patients, and a healthcare world rewriting itself in real time. What she saw inside patients' homes — medications scattered on tables, food insecurity, missing transportation — changed how she thinks about every chart she's ever read. You'll hear: Why a nurse-first pathway gives nurse practitioners a fundamentally different lens than a medical school pathway — and why patients feel it What working across home care, telehealth, trauma, and wellness teaches you about treating the whole human, not just the diagnosis Why trauma surgery turned Jacqueline into a believer in proactive, longitudinal care — and what gets missed when we only meet patients after something has already gone wrong The two words she uses to describe what's most broken in traditional healthcare: fragmentation and misalignment How empathy stops being a poster and starts being operational — built into the design of care itself If you've ever felt invisible inside the healthcare system, or if you're the one trying to fix it, this conversation reframes the whole game. Press play. www.YourHealth.Org

Refactoring Podcast
The State of Product Development

Refactoring Podcast

Play Episode Listen Later May 15, 2026 60:37


Today's guest is Doug Peete, Chief Product Officer at Atono, with whom over the last few months we have developed a deep industry report about the state of product development.In this chat we'll go through the main findings of the report, match them to our respective experience and explore ideas about how teams can do better with product development and AI(00:00) Episode start(01:38) Introduction(02:39) Sponsor break(05:38) Frailty of planning process(10:58) Product(13:19) What needs to be done(20:38) Design reviews(26:33) How to improve requirements(27:41) Knowledge across teams(35:07) Capturing the history of a product(39:14) Enabling sharing process(47:17) New metrics in AI era(50:47) AI in product requirements and products specs-Today's episode is brought to you by Unblocked.Unblocked is the context layer for modern engineering teams.Get a free three-week trial at getunblocked.com/refactoring-You can also find this at:•

ASCO eLearning Weekly Podcasts
Beyond Chronological Age: Assessing Frailty in Older Adults With GU Cancer

ASCO eLearning Weekly Podcasts

Play Episode Listen Later May 11, 2026 20:38


Dr. Hope Rugo and Dr. Peter Lee discuss frailty, geriatric assessments, and personalized care for older adults with genitourinary cancer. They highlight screening guidelines, treatment considerations, multidisciplinary interventions, and the emergence of AI and digital health tools in geriatric oncology. LINK TO FULL TRANSCRIPT    

Edgewater Christian Fellowship
The Grind: Ecclesiastes 5:8–6:12 – Bridge to Nowhere

Edgewater Christian Fellowship

Play Episode Listen Later May 10, 2026 39:12


Ecclesiastes 5:8–6:12 - exposes the emptiness of trusting in government, money, possessions, or achievement to give lasting meaning. Solomon shows that wealth and success often increase anxiety rather than peace, and a life spent chasing more can still leave the soul unsatisfied. Even under God's sovereignty, human choices still matter, and people remain responsible for how they live and what they pursue. Instead of building life around endless striving, Solomon points toward a quieter rhythm of flourishing: enjoy meals with others, work faithfully, accept your limits, and practice gratitude. True joy is found not in prestige or accumulation, but in receiving everyday life as a gift from God, marked by contentment, meaningful work, shared community, and thankfulness toward the Giver of every good thing.

Pre-Hospital Care
Frailty, Falls, Delirium & Handover: Navigating Complexity in Geriatric Emergency Care

Pre-Hospital Care

Play Episode Listen Later May 6, 2026 62:32


This geriatric compilation explores the intersecting challenges of frailty, falls, and delirium in older adults, core issues in both pre-hospital and acute care. Frailty increases vulnerability to injury and poor outcomes, with falls often resulting in hospitalisation, loss of independence, and increased mortality. Alongside this, delirium remains common yet frequently under-recognised, often triggered by infection, dehydration, medications, or chronic disease, and presenting significant diagnostic and management challenges.We examine structured approaches to assessment, including frailty scoring and cognitive evaluation, alongside the practical realities of decision-making in time-critical environments. A key focus is the differentiation between delirium, dementia, and other causes of confusion, and how sensory impairments can further complicate communication and assessment. The episode emphasises the importance of empathy, particularly when engaging with patients and families during periods of acute vulnerability.Attention is given to the interface between pre-hospital and hospital teams, exploring barriers to effective communication, the importance of structured handovers, and the development of proactive, multidisciplinary care pathways to reduce recurrent harm. Ethical considerations, family dynamics, and prevention strategies are also discussed.Featuring insights from Iain Wilkinson, James Adams, and Georgie Gill, this episode highlights integrated, system-wide approaches to improving outcomes for older patients.You can listen to the individual episodes here: Frailty in Geriatric Patients with Iain Wilkinson and James Adams. Part 1, Geriatric Series: https://podcasts.apple.com/gb/podcast/frailty-in-geriatric-patients-with-iain-wilkinson/id1441215901?i=1000695425594Delirium, Confused States, and Elderly Pathologies with Iain Wilkinson and James Adams. Part 2, Geriatric Series: https://podcasts.apple.com/kz/podcast/delirium-confused-states-and-elderly-pathologies-with/id1441215901?i=1000698533443Improving communication and decision-making within Geriatric care. Part 3, with Iain Wilkinson and Georgie Gill: https://podcasts.apple.com/kz/podcast/improving-communication-and-decision-making-within/id1441215901?i=1000700542486⁠This episode is sponsored by PAX: The gold standard in emergency response bags.When you're working under pressure, your kit needs to be dependable, tough, and intuitive. That's exactly what you get with PAX. Every bag is handcrafted by expert tailors who understand the demands of pre-hospital care. From the high-tech, skin-friendly, and environmentally responsible materials to the cutting-edge welding process that reduces seams and makes cleaning easier, PAX puts performance first. They've partnered with 3M to perfect reflective surfaces for better visibility, and the bright grey interior makes finding gear fast and effortless, even in low light. With over 200 designs, PAX bags are made to suit your role, needs, and environment. And thanks to their modular system, many bags work seamlessly together, no matter the setup.PAX doesn't chase trends. Their designs stay consistent, so once you know one, you know them all. And if your bag ever takes a beating? Their in-house repair team will bring it back to life.PAX – built to perform, made to last.Learn more at ⁠https://www.pax-bags.com/en/⁠

Clinical Update
Falls in older people and what GPs can do to prevent them

Clinical Update

Play Episode Listen Later May 6, 2026 16:12


In this episode of the Clinical Update podcast, MIMS Learning editors Pat and Sangeeta discuss falls in older people, highlighting tips on assessment, the benefits of exercise, and the role of deprescribing in primary care.Falls among older people cost the UK health and care system an estimated £4.4bn annually. Drawing on insights from consultant geriatrician Dr Anna Steel and NICE and British Geriatrics Society (BGS) guidance, Pat and Sangeeta cover multifactorial risk assessments and the ‘exercise as a drug' approach.The editors highlight the critical importance of medication reviews, particularly focusing on ‘FRIDs' (falls risk-increasing drugs). As Dr Steel notes, patients often value their immediate quality of life and mobility over long-term cardiovascular protection, making shared decision-making essential. The episode also details pragmatic prescribing targets for blood pressure and diabetes in frail patients to minimise harm.Educational objectivesAfter listening to this podcast, healthcare professionals should be better able to:Understand the significant economic and personal impact of falls in the UKIdentify the ‘exercise as a drug' approach to improve muscle mass and balanceConsult NICE guidance for recommendations on assessment and deprescribing Recognise fall-risk increasing drugs (FRIDs) and deprescribing tools to useUnderstand pragmatic clinical targets for blood pressure and glucose in frail patientsYou can access the website version of this podcast, along with a list of key learning points, on MIMS Learning - and make notes for your appraisal. MIMS Learning offers hundreds of hours of CPD for healthcare professionals, along with a handy CPD organiser.Please note: this podcast is presented by medical editors and discusses educational content written or presented by doctors, nurses and other healthcare professionals on the MIMS Learning website and at live events.MIMS Learning Register for FREEFrailty: clinical reviewHeart failure and frailtyA practical guide to conducting a structured medication reviewRecurrent falls in older people Hosted on Acast. See acast.com/privacy for more information.

A Cut Above: Horror Review
E249: Good Boy (2022)

A Cut Above: Horror Review

Play Episode Listen Later Apr 27, 2026 119:19 Transcription Available


Episode 249: Deja vu hits us pretty hard this week as we review yet another film named Good Boy about a dog, but this one is from 2022 and Norwegian. Does it have the same bark or bite? Find out.Make sure to check back with us next week as we reveal all our sins, with 2001's Frailty.Become a supporter of this podcast: https://www.spreaker.com/podcast/a-cut-above-horror-review--6354278/support.

A Cut Above: Horror Review
E250: Frailty (2001)

A Cut Above: Horror Review

Play Episode Listen Later Apr 27, 2026 136:36 Transcription Available


Episode 250: This week we have an axe to grind for Bill Paxton's 2001 hidden gem Frailty.With axe expert and podcast demon Charlie of Give Me Back My... the Podcast , on to give us aid in the fight against pure evil.Don't forget to come back next week, to celebrate 4/20 with 2006's Evil Bong.Become a supporter of this podcast: https://www.spreaker.com/podcast/a-cut-above-horror-review--6354278/support.

Red Whale Primary Care Pod
Don't miss it, don't harm them: brain tumour clues, and considering cancer and frailty

Red Whale Primary Care Pod

Play Episode Listen Later Apr 24, 2026 45:23


Send us Fan MailHeadache in the consultation room is common; a brain tumour is (thankfully) not — and that's exactly why we're so prone to worry and to miss the subtle clues. In this episode, Nik and Fi cut through the noise on headaches, red flags and brain tumours. They explore how no single symptom reliably hits the NICE “refer” threshold, what to do with “headache +” and “cognitive +”, when to push for urgent imaging/referral, and how to safety net adults and children. Then they move on to a quietly game-changing topic: cancer and frailty — how to spot it, why it alters investigation and treatment risk, what to include in suspected cancer referrals, and practical steps that primary care clinicians can start today to reduce harm and improve outcomes.Useful LinksPrehabilitation resources for healthcare professionals | Macmillan Cancer SupportMalnutrition Universal Screening Tool: MUST Macmillan Cancer Support - healthy eating and cancer GP Trainee Essentials support package information, and the Red Whale CalendarSend us your feedback podcast@redwhale.co.uk or send a voice message Sign up to receive Pearls here. Pearls are available for 3 months from publish date. After this, you can get access them plus 100s more articles when you buy a one-day online course from Red Whale OR sign up to Red Whale Unlimited.  Find out more here. Follow us:  Facebook, Instagram, LinkedInDisclaimer: We make every effort to ensure the information in this podcast is accurate and correct at the date of publication, but it is of necessity of a brief and general nature, and this should not replace your own good clinical judgement, or be regarded as a substitute for taking professional advice in appropriate circumstances. In particular, check drug doses, side-effects and interactions with the British National Formulary. Save insofar as any such liability cannot be excluded at law, we do not accept any liability for loss of any type caused by reliance on the information in this podcast.

Move Your DNA with Katy Bowman
Determining if you're FRAIL (or "Pre-Frail") and What to do About it

Move Your DNA with Katy Bowman

Play Episode Listen Later Apr 17, 2026 56:43


Frailty isn't just something that happens “later”; it's a gradual loss of resilience that can begin much earlier than most people think. Katy Bowman and Dr. Jeannette Loram unpack what frailty and pre-frailty mean biologically. They explore the five key hallmarks used to identify frailty, including walking speed and grip strength, and how a large proportion of people in their 30s and 40s already fall on the spectrum of pre-frailty.The conversation also explores the muscle–gut connection, explaining how frailty is influenced by exercise, diet, and the health of your microbiome. Katy and Jeannette also discuss the potential for rapid-onset frailty linked to the use of GLP-1 medications.Most importantly, frailty can be reversed and this episode focuses on what you can do. From simple ways to improve resilience through movement, nutrition, and rest, to understanding how your attitude toward aging might influence your resilienceEnhanced Show Notes and Full Transcript00:00 – Intro + Sponsors  01:30 – What Is Frailty (and Pre-Frailty)  03:00 – The 5 Hallmarks of Frailty  10:50 – How Pre-Frailty Can Start in Your 30s  12:40 – Muscle–Gut Connection & the Microbiome  19:40 – Exercise as “Fuel” for Your Microbiome  27:30 – Supplementation and the Psychology of Change  29:50 – GLP-1 Medication & Rapid-Onset Frailty  42:20 – Listener Question: Finding Glute Strength (Sponsored by Peluva)Resources and Books Mentioned:Joyspan by Kerry Burnight Frailty Sets In Far Earlier Than You'd Expect But You Can Reverse It, by David Cox in the New Scientist Frailty and pre-frailty in middle-aged and older adults and its association with multimorbidity and mortality: a prospective analysis of 493 737 biobank participants by Hanlon et al 2018Evidence For The Contribution Of Gut Microbiota To Age-Related Anabolic Resistance by Watson et al 2021Semaglutide Therapy and Accelerated Sarcopenia in Older Adults With Type-2 Diabetes: A 24-Month Retrospective Cohort Study by Ren et al 2025Connect, Move & Learn:Join Our Newsletter: Movement Colored GlassesFollow Katy on SubstackTry Katy's Virtual Studio Free for 7 days!Made Possible By Our Wonderful Sponsors:.My Happy Feet: Toe-spacing socks that gently realign toes for comfortable recovery—take 20% off with code MYDNAIkaria Design: The Soul Seat® offers height-adjustable, multi-position sitting—get 10% off new chairs and desks with code DNA10Venn Design: Beautifully upholstered ball-shaped Air Chairs that encourage dynamic sittingPeluva: Five-toe minimalist shoes that move like you do—take 10% off with code NUTRITIOUSMOVEMENTSmart Playrooms: Beautiful playroom design and movement-rich equipment—save 10% on monkey bars and rock-wall items with code DNA10Movemate: Active standing boards with smoothly articulating wooden slats. Designed to keep you moving without interrupting your focus.Thoughts/questions email us at podcast@nutritiousmovement.comYour Voice on the Podcast: Read The Credits 

The Hello, Sidney Podcast
Episode 182: Frailty (2001)

The Hello, Sidney Podcast

Play Episode Listen Later Apr 15, 2026 65:57


In this episode, Sidney breaks down a movie with not one, but two unexpected twists, Frailty (2001).

Intelligent Medicine
Leyla Weighs In: How Long-Term Statin Use Affects Muscle Mass and Strength

Intelligent Medicine

Play Episode Listen Later Apr 3, 2026 24:14


Leyla Muedin, a registered dietitian nutritionist, discusses a UK Biobank analysis published in the Journal of Cachexia, “Sarcopenia and Muscle” (Nov 2025) linking continuous long-term statin use (e.g., Lipitor, Zocor, Crestor) to accelerated declines in grip strength and appendicular lean mass compared with never-users. Among 35,557 with follow-up data, grip strength declined by a mean 0.315 kg/year and appendicular lean mass by 0.057 kg/year in statin users; findings persisted after adjustment for age, sex, BMI, comorbidities, and a pharmacogenomic statin-response score. Leyla notes possible mechanisms (CoQ10/mevalonate pathway effects, mitochondrial dysfunction, apoptosis, calcium disruption, insulin resistance) and advises monitoring musculoskeletal health, supporting diet and regular physical activity, while not interpreting results as a reason to stop prescribing statins.

Managed Care Cast
Frailty, Innovation, and the Future of Myeloma Treatment With Joseph Mikhael, MD

Managed Care Cast

Play Episode Listen Later Mar 31, 2026 28:06


Joseph Mikhael, MD, MEd, FRCPC, FACP, FASCO, chief medical officer with the International Myeloma Foundation and professor in the Applied Cancer Research and Drug Discovery Division of the Translational Genomics Research Institute, has spent more than 25 years advancing the treatment of multiple myeloma. In this episode, he breaks down how improved survival, evolving frailty assessments, and the rise of therapies like CAR T and bispecific antibodies are reshaping care for an aging population, and he highlights the growing emphasis on quality of life, caregiver support, and expanding clinical trial access.

Intelligent Design the Future
The Cultural Mythology and Scientific Frailty of Darwinism

Intelligent Design the Future

Play Episode Listen Later Mar 30, 2026 28:50


Why has Darwin's theory of evolution succeeded so dramatically? The official story, of course, is that it provides a sweeping and complete explanation of the development of life on Earth, with the claim that it's rock solid because it's grounded in an abundance of evidence. But when we take a closer look at that official story, we see that it actually resembles more of a myth, a legendary origin story that has been championed and propped up successfully for over 160 years. On this ID The Future, host Andrew McDiarmid treats you to a reading from False Messiah, a book by Neil Thomas recently published by Discovery Institute Press. The book provides valuable insight around the mythology of Darwinism as well as the mythical figure of Charles Darwin himself. To help us understand why Darwinism has persisted for so long, it's helpful to take a closer look at the forces that moved it forward and upheld it, lest we be tempted to think it has succeed purely on the strength of its scientific arguments. Source

Discovery Institute's Podcast
The Cultural Mythology and Scientific Frailty of Darwinism

Discovery Institute's Podcast

Play Episode Listen Later Mar 30, 2026 28:50


The Podcast That Wouldn’t Die!

Kevin and Erin discuss the horror "Classic": Frailty. Spoilers aplenty! Like and share this episode, and check us out at https://linktr.ee/TPodcastTWDie. TJ from http://introoutrobed.com custom-made our music! Use my special link https://zen.ai/OPqxxQiaqgDLKVIziDbCE-bL9F-GRRqYLBJ5f6qmlwU to save 30% off your first month of any Zencastr paid plan.

JACC Speciality Journals
Frailty Status Predicts Adverse Outcomes in Ambulatory Heart Failure With Preserved Ejection Fraction | JACC: Advances

JACC Speciality Journals

Play Episode Listen Later Mar 25, 2026 2:50


Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Frailty Status Predicts Adverse Outcomes in Ambulatory Heart Failure With Preserved Ejection Fraction.

2002: A Film Odyssey
Episode 43: FRAILTY

2002: A Film Odyssey

Play Episode Listen Later Mar 23, 2026 123:01


We welcome Joe Begos, Josh Ethier, and Matt Mercer on the show to chat Frailty, the Collateral soundtrack, and many more tangents.

BackTable OBGYN
Ep. 108 Treating Urogynecologic Frailty: Perioperative Strategies for Surgeons with Dr. Mary Ackenbom

BackTable OBGYN

Play Episode Listen Later Mar 10, 2026 56:29


As our patients' age progresses, so should our definition of 'recovery'. In this episode of BackTable OBGYN, Dr. Mary Ackenbom, associate professor of urogynecology and reconstructive pelvic surgery at the University of Michigan, is welcomed by host Dr. Amy Park to discuss improving outcomes for older surgical patients. --- SYNPOSIS Dr. Ackenbom shares her journey from studying finance at Ohio State to ultimately specializing in urogynecology. The conversation mainly focuses on perioperative cognitive health, particularly in aging populations, and how conditions like frailty and comorbidities impact surgical risk and recovery. Dr. Ackenbom highlights the importance of individualized patient care, early mobility, enhanced recovery protocols, and prehabilitation in improving postoperative outcomes. The episode also explores the prevalence of postoperative cognitive decline and offers practical insights on counseling and managing older patients undergoing urogynecologic surgery. --- TIMESTAMPS 00:00 - Introduction02:18 - Dr. Ackenbom's Journey to Urogynecology04:47 - Research on Brain Fog06:18 - Personal Support and Hobbies09:54 - Age vs Frailty in Surgery13:05 - Procedures with Perioperative Complexity16:11 - Counseling on Operative Risk20:10 - ERAS and Earlier Discharge23:35 - Patient Goals and Tradeoffs27:53 - Surgical Clearance and Preop Consults33:30 - Prehabilitation Basics36:24 - Minimally Invasive Surgery Benefits37:15 - Surgical Cognitive Complications with Age41:42 - Finding the Surgery Window46:05 - Cognitive and Frailty Screening50:01 - Guidelines for Perioperative Care52:52 - Future Research 54:07 - Conclusion --- RESOURCES Incidence of postoperative cognitive dysfunction in older women undergoing pelvic organ prolapse surgeryhttps://pubmed.ncbi.nlm.nih.gov/32827107/ ACS NSQIP/AGS Optimal Perioperative Care of the Geriatric Patienthttps://www.facs.org/media/y5efmgox/acs-nsqip-geriatric-2016-guidelines.pdf

You Are My Density
135: Frazzled by the Rush

You Are My Density

Play Episode Listen Later Mar 10, 2026 18:52


Mommie dearest, the worst video ever produced, a truly great Kennedy, Abraham Lincoln and ecstasy, a vile word, don't fuck with my eye drops, a Guns N' Roses disaster, get Ruffalo some Ex-Lax, a kind of a boring day at the movies, a Nick Nolte sighting, a really enjoyable random Richard Gere movie, the cool as hell Will Patton, my favorite Carradine, a somewhat despicable woman, some streaming selections, and the sweet smell of success. Stuff mentioned: Secretary Kennedy and Kid Rock's Rock Out Workout (https://www.instagram.com/reel/DU33MUgiWo5/?hl=en), Cobra (1986),  Airplane (1980), Guns N' Roses "Welcome to the Jungle" (1987), Crime 101 (2026), Safe Men (1998), Heat (1995), The Mothman Prophecies (2002), The Butterfly Effect (2004), Coma (1978), Revenge of the Nerds (1984), 8 Million Ways to Die (1986), Frailty (2002), Blow Out (1981), Shocker (1989), Dragged Across Concrete (2018), and Unlawful Entry (1992), and Magnum, P.I. (1980-1988).

Spinsterhood Reimagined
The One Where I Talk To Author & Journalist, Poorna Bell

Spinsterhood Reimagined

Play Episode Listen Later Mar 3, 2026 76:14


Send a textMy guest this week is Poorna Bell, an award-winning author, journalist, public speaker and former executive editor at the Huff Post. Her sixth book, (and fourth non-fiction book) She Wanted More, came out just last month, and shines a much-needed spotlight on the lives of women in their 40s, 50s, 60s and beyond, challenging the stagnation narratives that society tries to force upon us. The book explores various themes including the distinction between motherhood and otherhood, diving into the reality that women can be childfree and still live lives of purpose and meaning. Our conversation includes: the tragic loss of Poorna's husband Rob; how society still sees marriage as the superior path; her thoughts on the viral Vogue article, 'Is Having A Boyfriend Embarrassing Now?'; Poorna's current outlook on dating; decentering men, i.e. removing them as the focal point in our lives; the impossible standards placed on women when it comes to ageing; and Poorna's new book, She Wanted more. 05:28 Poorna's Story: Losing Her Husband & Rethinking the 'Life Script'09:25 10 Years On: Grief, Healing, and Finding Joy & Peace Again16:06 From Wife to Widow to Single: Status, Stigma, and Solo Travel22:23 Dating Pressure25:25 Viral Vogue article ‘Is Having A Boyfriend Embarrassing Now?' + Why Women's Lives Get Harder with Men34:20 Why She Wrote ‘She Wanted More': Aging, Reinvention, and Rejecting the Decline Narrative38:13 Older Women Athletes & Rewriting the ‘Frailty' Narrative40:07 Aging as Liberation: Social Media Role Models in Their 60s43:17 Letting Go of the Male Gaze47:53 Desire, Menopause & the Many Realities of Midlife Sex49:49 Heidi Clements, HRT, Money & Why Friendship Matters More Than Romance52:54 Decentering Men: Putting Yourself Back at the Center55:50 Are We Escaping the Patriarchy? Measuring Progress (and What's Missing)59:50 Dating Burnout, Quitting Drinking & Dipping a Toe Back Into Dating01:05:12 Online Dating Reality Check: Hybrid Dating, Expectations & Efficiency01:08:46 Final Words of AdviceBuy Poorna's book, She Wanted More: https://www.amazon.co.uk/She-Wanted-More-space-dream/dp/1785122835Follow Poorna on Instagram: https://www.instagram.com/poornabell/?hl=enFollow Poorna on TikTok:  https://www.tiktok.com/@poornabell Support the showBuy my book, SHINY HAPPY SINGLES (UK) / THRIVE SOLO (US & Canada) at: https://www.lucymeggeson.com/book Join my membership community for single women, Thrive Solo: https://www.lucymeggeson.com/thrivesolo Download my FREE PDF 'Top 10 Comebacks for the MostAnnoying Questions Single Women Get Asked' Go to: https://www.lucymeggeson.com/comebacks Check out my YouTube Channel: https://www.youtube.com/@thrivesolowithlucymeggeson Join my private Facebook Group: https://www.facebook.com/groups/1870817913309222/?ref=share Follow me on Instagram: https://www.instagram.com/thrivesolowithlucymeggeson/ Email me: lucy@lucymeggeson.com And thank you so much for listening!

Cardionerds
442. Heart Failure: LVAD Part 1 with Dr. Jeff Teuteberg and Dr. Mani Daneshmand

Cardionerds

Play Episode Listen Later Feb 27, 2026 41:37


CardioNerds (Dr. Jenna Skowronski [Heart Failure Council Chair], Dr. Shazli Khan, and Dr. Josh Longinow) are joined by renowned leaders in the field of AHFTC (Advanced Heart Failure and Transplant Cardiology) and mechanical circulatory support, Dr. Jeff Teuteberg and Dr. Mani Daneshmand to continue the discussion of advanced heart failure therapies by taking a deep dive into the world of durable LVADs (Left Ventricular Assist Devices). In this episode, we will review the history of ventricular assist devices, the basics of LVAD function, selection criteria for LVAD therapy, and surgical nuances of LVAD implantation. Audio Editing by CardioNerds intern, Joshua Khorsandi. Enjoy this Circulation 2022 Paths to Discovery article to learn about the CardioNerds story, mission, and values. CardioNerds Heart Success Series PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls There have been significant advances in the field of MCS/LVAD therapy since the first implanted LVAD in the 1960s, to the first FDA approved device in the early 2000's, to now the HM3 LVAD, with the most important change being a centrifugal flow/magnetically levitated design that led to minimized hemocompatibility-related adverse events (HRAE's) (MOMENTUM 3 trial comparing HM2 and HM3).  The REMATCH trial in 2001 was a pivotal trial for LVAD therapy, demonstrating that in a population of patients with advanced HF (70% IV inotrope dependent), LVAD therapy significantly improved survival at both 1 and 2 years as compared to medical therapy alone.    MOMENTUM 3 trial was a landmark trial for the HM3 device, showing that in a population of end stage HF patients (86% inotrope dependent, 32% INTERMACS 1-2, and 60% DT strategy), 5-year survival with HM3 was 58% and HM3 had lower HRAE's compared with HM2.  There are both patient-specific factors and surgical considerations when it comes to candidacy for LVAD therapy.  RV function prior to LVAD is a key determinant for success post-LVAD  Many patients being considered for LVAD may not have robust RV function, however, predicting RV failure after LVAD is exceedingly difficult.   In general, it doesn’t matter how bad the RV may look on imaging; we care more about the pre-LVAD hemodynamics (look at the PAPi and RA/wedge ratio).   What happens in the OR may be the most important determinant of how the RV will do with the LVAD!  Notes Notes drafted by Dr. Josh Longinow.  1. Historical background of heart pumps and LVADs  LVAD Evolution   FDA approval year  2001  2008  2012  2017  Pump  HeartMate XVE   HeartMate II  Heartware HVAD  HeartMate III  Flow/Design Features  Pulsatile Technology   Continuous flow Axial design  Continuous flow  Centrifugal design  Continuous flow   Full MagLev + Centrifugal design  The 1960's ushered in the first ‘LVADs', when the first air-powered ‘LVAD' was implanted. It kept the patient alive for four days before the patient expired.   The first generation of LVADs were pulsatile pumps   The first nationally recognized, FDA approved LVAD was the HeartMate XVE (late 1990s to early 2000s, REMATCH trial). The XVE pump used compressed air (pneumatically driven) to power the pump.   Prior to the XVE, OHT was the standard of care for patients with advanced, end-stage heart failure.   The second and third generations of LVADs were non-pulsatile, continuous flow devices and included the HVAD, HM2, and HM3 devices.   MOMENTUM 3 was a landmark trial for the HM3 device, showing that in a population of sick patients with end stage HF (86% inotrope dependent, 32% INTERMACS 1-2, and 60% DT strategy), 5-year survival with HM3 was 58% and HM3 had lower HRAE's compared with HM2.   The only pump that is currently FDA approved for implant is the HM3, although other pumps are in clinical trials (BrioVAD system, INNOVATE Trial).  2. What are LVADs, and how do they work?   In simplest terms, the LVAD is a heart pump comprised of several key mechanistic components:   Inflow cannula  Mechanical pump   Outflow cannula  Driveline  Controller/Power source  The HM3 differs from its predecessors (HM2 and HVAD) in several key ways;   HM3 is placed intrapericardial whereas the HM2 was placed pre-peritoneal.   Perhaps most importantly, the HM3 is a fully magnetically levitated, centrifugal flow pump, whereas the HM2 is an axial flow device.  Axial flow pumps are not magnetically levitated, leading to more friction produced between the ruby bearing's contact with the pump rotors, and higher rates of hemocompatibility related adverse events (HRAEs, i.e. pump thrombosis) and the HM2 was ultimately discontinued in favor of the HM3 (MOMENTUM 3 trial).  3. What do the terms ‘Destination Therapy' (DT) or ‘Bridge to Transplant' (BTT) mean when it comes to LVADs?   When LVADs first came on the stage, EVERYONE was a BTT; these early pumps weren't designed for long term use (I.e. REMATCH Trial, Heartmate XVE)  Destination therapy means the LVAD was placed in leu of transplant because there are contraindications to transplant   REMATCH trial brought about the concept of “Destination therapy”, comparing outcomes in patients (with contraindications for transplant) who received an LVAD vs optimal medical therapy  Bridge to transplant means we are placing the LVAD in a patient who may not be a transplant candidate at this moment in time (is too sick, or conversely, not sick enough), but may be down the line   Bridge to recovery is another term used when the LVAD is being placed for a patient we think may have a recoverable cardiomyopathy  4. What are some factors we should consider when assessing a patient’s candidacy for LVAD, in general, and from a surgical perspective?   Patient factors   Older age might push us towards thinking LVAD rather than transplant  In general, age > 70 is the cutoff for transplant, but this is not a hard cut off and varies institution to institution    In general, think about things that help predict recovery after a major surgery; Frailty and Nutritional status are important, we try to optimize these prior to LVAD implant   Right ventricular function remains the Achilles heel of LV support  We know that needing temporary RV support post LVAD puts you on a different survival curve than patients who don’t need RVAD support  Studies have not been able to successfully predict who will develop RV failure after LVAD implantation  What happens in the time between when the patient goes to the OR and when they get back to the ICU is an important determinant who might develop RV failure post LVAD   Surgical techniques such as implanting the HM3 in the intra-thoracic cavity, rather than intra-pericardial may help maintain LV/RV geometry to help optimize the RV post LVAD   Surgical considerations for LVAD candidacy  Small, hypertrophied LV: HM3 inflow cannula is small, but small hypertrophied ventricles tend towards chamber collapse during systole causing suction, needing to run slower with lower flow rates  Chest size/diameter: pumps have gotten so small now, that for adults, these have become less of a consideration  BMI: low BMI used to be more of a concern with the older pumps due to where they were placed, and the relative size of the pump itself, not so much now with the smaller HM 3 pumps  Calcified LV apex: would increase risk of stroke, bleeding   Driveline tunneling becomes a concern in the super obese population, higher risk for driveline infections (might tunnel these driveline's shorter, and to a less fatty region of the abdomen, could even tunnel out the thoracic cavity in the super obese to limit skin motion)    5. Is there a role for MCS (i.e. temporary LVAD such as Impella) in pre-habilitation of patients prior to LVAD surgery?   The theory of being able to improve systemic perfusion, decongest the organs, and make the patient feel better prior to surgery makes sense, but becomes problematic due to the lack of a hard end point/time for prehabilitation which might risk delays in surgery   More likely that it can lead to delay in the surgery, with less-than-optimal benefit; you don't want to prolong the wait for surgery and increase the risk for complications prior to surgery    An Impella 5.5 is currently FDA approved for 2 weeks of support, not 2 months so timing is important to keep in mind  It’s unlikely that you will take a patient and convert them from a malnourished, cachectic person in 2 weeks’ time   6. Is there a role for LVAD therapy in the younger patient population? Should we be thinking of LVAD up front for these patients, with the goal of transplanting down the line?   Recovery may be more likely in certain populations, particularly younger females with smaller LV's; in those populations, perhaps bridge to recovery should be the focus, optimizing them on GDMT etc.   The replacement of transplant, with MCS (LVAD) in young patients has become a topic of discussion, because these pumps have become better and better, with the thinking that an LVAD could bridge a patient for 10 years or so, and they could get a transplant later   It is still a big unknown, but several concerns exist  Patients who get LVADs might end up with complications that become contraindication to transplant down the line (stroke, sensitization etc)   Patients and providers are more hesitant because of the more recent iteration for the UNOS criteria for OHT listing which no longer gives patients with an uncomplicated LVAD higher priority, and therefore they could end up waiting a longer time for a heart after undergoing LVAD  References Rose EA, Gelijns AC, Moskowitz AJ, et al. Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med. 2001;345(20):1435-1443. doi:10.1056/NEJMoa012175  Mehra MR, Uriel N, Naka Y, et al. A Fully Magnetically Levitated Left Ventricular Assist Device – Final Report. N Engl J Med. 2019;380(17):1618-1627. doi:10.1056/NEJMoa1900486  Mancini D, Colombo PC. Left Ventricular Assist Devices: A Rapidly Evolving Alternative to Transplant. J Am Coll Cardiol. 2015;65(23):2542-2555. doi:10.1016/j.jacc.2015.04.039  Mehra MR, Goldstein DJ, Cleveland JC, et al. Five-Year Outcomes in Patients With Fully Magnetically Levitated vs Axial-Flow Left Ventricular Assist Devices in the MOMENTUM 3 Randomized Trial. JAMA. 2022;328(12):1233-1242. doi:10.1001/jama.2022.16197  Rose EA, Moskowitz AJ, Packer M, et al. The REMATCH trial: rationale, design, and end points. Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure. Ann Thorac Surg. 1999;67(3):723-730. doi:10.1016/s0003-4975(99)00042-9  Kittleson MM, Shah P, Lala A, et al. INTERMACS profiles and outcomes of ambulatory advanced heart failure patients: A report from the REVIVAL Registry. J Heart Lung Transplant. 2020;39(1):16-26. doi:10.1016/j.healun.2019.08.017  Mehra MR, Netuka I, Uriel N, et al. Aspirin and Hemocompatibility Events With a Left Ventricular Assist Device in Advanced Heart Failure: The ARIES-HM3 Randomized Clinical Trial. JAMA. 2023;330(22):2171-2181. doi:10.1001/jama.2023.23204  Mehra MR, Nayak A, Morris AA, et al. Prediction of Survival After Implantation of a Fully Magnetically Levitated Left Ventricular Assist Device. JACC Heart Fail. 2022;10(12):948-959. doi:10.1016/j.jchf.2022.08.002  Bhardwaj A, Salas de Armas IA, Bergeron A, et al. Prehabilitation Maximizing Functional Mobility in Patients With Cardiogenic Shock Supported on Axillary Impella. ASAIO J. 2024;70(8):661-666. doi:10.1097/MAT.0000000000002170 

The Academic Imperfectionist
#126: Why you should care about emotional frailty

The Academic Imperfectionist

Play Episode Listen Later Feb 6, 2026 23:52 Transcription Available


You know what frailty is, and you definitely want to avoid it. But have you heard of emotional frailty? No, of course not - I've just made it up. But if you've ever felt like you're completely winning at life, and then some tiny little setback knocks you sideways, leaving you wondering what's wrong with you and why you suddenly can't cope, emotional frailty is to blame. Emotional frailty is invisible, it's dangerous - and often, the culture around us encourages us to do exactly the sorts of things that exacerbate it. It's time to fight back. Your Imperfectionist friend is here to show you how.Find the Wheel of Life exercise here.

Mary Lindow ~ The Messenger Podcast
Measuring The Honesty Of Our Own Hearts - Self Examination - Spiritual Growth - Emotional Blind Spots - Going Against the Flow

Mary Lindow ~ The Messenger Podcast

Play Episode Listen Later Feb 5, 2026 19:22


By Mary Lindow  I am by far not an expert on the subject of plumblines and righteousness, so take what I say in the light of one who at time gropes like a child in the dark, ever reaching for the hand of the ONE to lead me into a safe place filled with His Hope, His Mercy, His Light and Life. WE LIVE IN A CORRUPT WORLD and therefore, have the “effects and affects” of that corruption ever influencing, ever tainting and ever wooing the flesh.  Plumbline: a tool that consists of a small, heavy object attached to a string or rope and that is used especially to see if something (such as a wall) is perfectly vertical or in alignment)   A plumbline is a simple but accurate tool used for determining whether or not something is perfectly vertical or upright. The Lord also used, and uses, a "plumbline," His Word, to determine how upright His people truly are in His sight. How upright they think they are, or how upright they proclaim themselves to be, means nothing to God. "Behold, I WILL set a plumbline in the midst of My people".  -Amos 7:7  A PLUMBLINE SET OUT BY THE HAND OF GOD IS ONE THAT WE CAN ANCHOR OUR HEARTS TO. It will always, always, ALWAYS, direct us to the truth in a matter; even if it requires pain, loss, persecution and perhaps death in areas we feel we may well have rights to.  It will also be a shield, a balm, a comfort and a teacher to those who will yield to the directive positioning of the Master.  “I will make justice the measuring line and righteousness the plumbline.” -Isaiah 28:17  LIFE – DISTRESS - AND PERSECUTION  I have found that in my life, distress and persecution do not feel like God's care being poured out on me. My heart is not immediately drawn to thanksgiving and gratefulness for the faithfulness of God on display as I cling to the battered pieces that look like potential “rafts” of hope, only to find out that many of them have gaping holes or slow leaks in them.  Rather, it feels like yet another hurt is being permanently woven into my tattered and war-torn soul. It seems as if another mound of questions are piling up and just waiting for an answer and a true solid REAL anchor of hope.  I CAN REALLY CONNECT TO THE WRITER OF PSALM 42  He said “Why are you cast down, O my soul, and why are you in turmoil within me?” It's at those very times that the words of the Savior are so important. When we are down and in turmoil.  But, how do we connect the dots between what we know is true about God's faithfulness and what our hearts feel? When flipped and flung around by the waves, weary from crying and when no answer seems at hand, what is the answer?  When my circumstances show many foes and tyrants rising up against me and my heart is prone to wander and fear, what hope is there of peace?  When my feelings start controlling my thoughts, how can I rest in God's promises?  AT THIS POINT… I HEAR THE “GASPS” …  …And perhaps shocked comments of a few who are amazed that someone who appears to walk so fervently and intimately with the Lord would have such difficulties!  Well! Guess what? I do struggle, I do hurt, and yes I do doubt when I have been side swiped or “rammed” by skilled cons and those who, although may have the appearance of godliness and offered friendship or fellowship, end up having private and evil agendas behind their well placed and planned schemes. And boy oh boy! Those skilled players know the wicked art of wounding the heart and causing people to reel in pain!  BUT, THERE IS ONE WHO FULLY SEES IT ALL  The main skill in the issue of dealing with life as a spiritual person, is to know how to handle yourself when things not only crush and grind your heart, but what to do with the anguish and toll of their aftermath.  We have to get ourselves into a place where we hear clearly again.  We need have to address ourselves, preach to ourselves, and ask questions about ourselves.  We must say to our soul: "Why are you cast down –Why are you so anxious and lacking in peace?"  We must urge ourselves, and say ‘Hope in God'–instead of remaining in this paralyzed, aching state!”  AND THEN WE MUST TAKE IT A STEP FURTHER We must go on to remind ourselves just “Who “God is, and what God is and what God has done, and what God has promised that he Himself said that He would do.  Having done that we can stand up and sing out strongly, defying the torment of the soul, and resist other people's wicked tongues and arrogance, and refuse to go along with the devil and the whole world, and say: ‘Hope in God; for I shall again praise him, my salvation and my God.”  The hope and promise of the fairness of God's justice when dealing with the hurtful things and presumptions of others gives me the confidence to know that God will never turn away from me in my need. No matter how they seem to prosper in the short term, wicked men and women will ultimately pay for their sins, in this life or the next. Jesus died to meet my greatest hardships and sorrows for me, and I need to preach this to myself every day. His power is greater than my weariness and suffering.  The comforting and instruction that comes from simply running to feed upon His word instead of the toxic poison of the replaying of trauma reminds me that what Jesus has done is strong enough for my soul to rejoice in and to be set into a place where it can rest and regroup, gaining a healthy perspective about what to give out to others and what is simply… …. To be enjoyed by the Lord Himself.  THE NATURAL IMPULSES OF MANKIND ARE SINFUL AND DECEITFUL!  Human willpower alone will never be able to change this.  We need God's help to truly change our hearts.  REMEMBER. You cannot change the heart of anyone else either.  If you try to, you will feel the bite of stinging venom or be laughed out of a room. Only the power of the conviction of the Holy Spirit can permeate and get around the jam-packed hardhearted egos of the self sufficient and bitter.  Jeremiah 17:9 says that the human heart is deceitful in all things and is even beyond cure! We must be cautious and wise in reproving and warning such types of people about their bad behaviors and wicked actions where there seems to be no appearance or hope of change and where there is danger of experiencing great and heart wrecking retaliation and slander.  These types trample the warnings and urging for repentance and humbling of the heart under their feet, and turn again and slash at you, despising the warnings that are “tearfully and fearfully” given, and often hurt the persons who give them, either by words or deeds.  "Don't waste what is holy on people who are unholy.  Don't throw your pearls to pigs!  They will trample the pearls,  then turn and attack you.”  -Matthew 7:6    "GIVE ME THE FACTS MA'AM JUST THE FACTS”  I remember that phrase from a TV show called “Dragnet”. The detective would not allow the details of the case to be skewed by any assumptions or pontificating from those he interviewed. He stoically and firmly demanded only the facts.  And so, here are the “facts” about the heart of a good man or woman. 1.) The good man or woman: Brings good things out of the good stored up in his/her heart. And the facts about an evil man or woman.  2.) The evil man/woman brings evil things out of the evil stored up in his/her heart. For out of the overflow of his or her heart his or her mouth speaks. Luke 6:45    THE FRAILTY, BRIEFNESS, AND INSECURITY OF LIFE  The frailty, briefness, and insecurity of life should hold down the vanity and presumptuous confidence of all of our projects and boasting about future greatness and bragging rights! We are always to depend on the will and leading of God.  OUR TIMES ARE NOT IN OUR OWN HANDS, BUT ARE INSTEAD IN THE TIMING OF GOD. Our heads may be filled with cares and plans for ourselves, or our families, or our friends; but Divine intervention often throws our plans into bewilderment. All we have in mind, and all we do, should be with a humble and deep dependence on God. It is foolish, and it is hurtful, to boast of trendy “latest happening” things and prospective projects, and it will bring great disappointment and will prove destructive to relationships and meaningful help to others in the end.  “For the world offers only a craving for physical pleasure, a craving for everything we see, and pride in our achievements and possessions. These are not from the Father, but are from this world.”  -1 John 2:16 LISTEN KINDLY - BEFORE SPEAKING YOUR THOUGHTS  People don't need a lecture on the meaning of suffering or to have a barrage of scriptures “machine-gunned” at them as a reprimand for sharing their moment of grief or struggle! (Especially when their hearts are breaking, weary of the battle and if they are fatigued.) Job could have done without some of the self-righteous answers that came from his “well-meaning” friends. All of the answers could have even been true, but Job didn't need to hear any of them.  He needed their love, not their value judgments.  In fact, it appears as if God judged THEM for trying to offer simple solutions to things that were beyond their comprehension. They had never walked in the loss he was in anguish over.  WHEN WE SUFFER UNJUSTLY WE HAVE A MAJOR CHOICE TO MAKE How will we respond? We can feel sorry for ourselves (and understandably so, for a while), become bitter and cynical, get drawn into a war of words, or even become mixed up in a major conflict. On the other hand, we can take our suffering to the cross and allow our pain to draw us into a deeper place of understanding of what Jesus went though in his sufferings. This does not remove the pain, but does help us to know what to do with our hurt.  This is the 'fellowship of his sufferings' (Philippians 3:10), one of the gateways to closeness with God and the release of his power in our lives. The weight of heartbreak shared with a loving friend cuts it in half. When the burden is shared with many friends, we can cope with almost anything. We never feel more revitalized than when a friend loves us enough to walk with us in our pain. Not lecture us.  The apostle Paul wrote these words to the church in Corinth:  "Praise be to the God and Father of our Lord Jesus Christ, the Father of compassion and the God of all comfort, who comforts us in all our troubles, so that we can comfort those in any trouble with the comfort we ourselves have received from God". -1 Corinthians 1.3-4  SOMETIMES GOD GETS INVOLVED WITH DIRECT MIRACLES, Giving supernatural strength to those in need. But for the most part, he depends on us, his people, to do his work in the world. We love each other, work for healing, and suffer with those who suffer.  The next time you see a friend who is suffering, Jesus may just invite you to be the warm embrace! We comfort each other with the comfort we have received in Christ. And when we do, we become the Body of Christ and he receives the glory!  THE BIBLE IS CLEAR!  We are to bear one another's burdens.  We are to comfort others as Christ has given comfort to us.  Your hard time becomes my hard time.  We join hands in the journey.  When you succeed, I succeed.  When you suffer, I suffer. But we do it together. We share it together.  And we do it, not so much in our wisdom or our words, but in our availability, our understanding, and through our presence.  THAT'S WHAT FELLOWSHIP IS ALL ABOUT!  But not “bland” fellowship. It is CHRISTIAN fellowship. It is the business of burden bearing. Authentic CHRISTIAN fellowship says that when you need me . . . I'll be there. Support in suffering is at the core of what it means to share life together in Christ. The word for "comfort” is the same root word as the name Jesus used to describe one of the functions of the Holy Spirit in our lives (Paraclete). “I will be a comforter, one who comes alongside to give help.” And so as God comes alongside you, now you are able to come alongside another. As the Comforter is at work within you, so you also can be of comfort to those around you.  WE ARE CALLED TO BEAR ONE ANOTHER'S BURDENS.  To mourn with those who mourn. To be a follower of Jesus means to come alongside people who are hurting and find ways to help them walk even through the valley of the shadow of death. We are called to do this, as the word of God and care of God is shared with the intention of stirring, plowing up hardened hearts, creating a place for repentance and challenging saints to hope again, I know and believe that as we learn again as believers, to care, to truly listen and to hope fully again, that the sweet and heavy weight of HIS Glory will be made known and will manifest in unfettered and uncontrolled waves of worship and spontaneous adoration of the King of Heaven.  HE REALLY DOES KNOW WHAT HE WANTS Let's focus on bowing low and seeking His heart and plans in what matters to Him. Indeed, HE is the Plumbline.  Prayer  God, I ask in Jesus' name, that you comfort, strengthen and encourage all who are hurting deeply right now and are going through so much pain and heartache.  Don't allow them to give up in the heat of the battle.  Let them feel your arms wrapping around them and your love overflowing and filling them up. Lord, I will pray often and I know that you will hear my voice, even when I speak to You in my silent thoughts.  To You, I am crying out and my prayers are now before You.  Father, I give to You my problems, I do not want them.  Father, please restore them to You. I know that you have compassion for your children. Father, show them your ways and teach them your paths. Lead them in your truth and teach them you are the God of our salvation and on you we will wait.  Protect them from the evils of this life and guide them through all of their days. Father, thank You for hearing my prayer Father and for considering and for having compassion on all who hear and read these words, and all who hurt, in this troubled world we live in.  Keep them in the center of Your love.  In Jesus' Name ~ Amen  Duplication and sharing of this message is welcomed provided that complete article, podcast link and website information for Mary Lindow is included.  Thank You Copyright © 2026 " THE MESSENGER " ~ Mary Lindow www.marylindow.com https://marylindow.podbean.com Your Gracious Support and Donations Are So Very Helpful And Assist Mary In Publishing Her Teaching Podcasts and Audio Messages. THANK YOU! Please go to PAYPAL to donate  or support this blog:  Donate to the tax-deductible ministry name of:  paypal.me/mlindow    (His Beloved Ministries Inc.)  Or  You Can Mail a Check or Cashiers Check to:  His Beloved Ministries INC  PO Box 1253  Eastlake CO 80614  United States    

Boundless Body Radio
Fracture-Proof Your Bones with Dr. John Neustadt! 939

Boundless Body Radio

Play Episode Listen Later Feb 4, 2026 55:47


Send us a textDr. John Neustadt, ND, is the Founder and President of Nutritional Biochemistry, Inc. (NBI). Dr. Neustadt earned his naturopathic medical degree from Bastyr University where he was awarded the Founder's Award for academic and clinical excellence.Dr. Neustadt is a highly sought-out speaker at medical conferences, and has been recognized as one of the Top Ten Cited Authors in the world for his work. His research on integrative and functional medicine has been featured in the Natural Medicine Journal, Integrative Medicine: A Clinician's Journal, Holistic Primary Care, Molecular Nutrition & Food Research, and Experimental and Molecular Pathology.Dr. Neustadt has published more than 100 medical articles, written four health and wellness books and is now a #1 Amazon Best Selling Author in the field of Osteoporosis. His most recent book is, Fracture-Proof Your Bones: A Comprehensive Guide to Osteoporosis.Dr. Neustadt was also an editor of the textbook Laboratory Evaluations for Integrative and Functional Medicine, which was used across the United States to train and educate physicians on using functional medicine with their patients.Find Dr. Neustadt at-https://www.nbihealth.com/Find Boundless Body at- myboundlessbody.com Book a session with us here!

DocTalk Podcast
Liver Lineup: Bridging Innovation and Practice in Liver Transplant and HCC Care

DocTalk Podcast

Play Episode Listen Later Feb 4, 2026 30:42


In this episode of Liver Lineup: Updates and Unfiltered Insights, hosts Kimberly Brown, MD, and Nancy Reau, MD, break down new research on liver transplantation, hepatocellular carcinoma (HCC), and the ongoing evolution of surveillance strategies in chronic liver disease. Drawing on their extensive experience as transplant hepatologists, Brown and Reau place new data into practical context, highlighting where evidence may meaningfully inform practice and where unanswered questions remain.Key episode timestamps:0:00:00 – Introduction0:00:19 – Frailty & Transplant Evaluation0:02:54 – How Centers Use Frailty Measures0:04:37 – Practicalities of the Six‑Minute Walk0:06:10 – MELD 3.0 and Sex/Size Disparities0:08:42 – Exception Points & Size Constraints0:10:05 – Need for a Dynamic MELD System0:10:19 – Immunotherapy as Bridge/Downstaging for HCC0:13:34 – Real‑World Use of IO Around Transplant0:15:22 – Managing Rejection Risk0:19:03 – MASLD Population & Surveillance Gaps0:20:21 – Adherence to HCC Surveillance0:22:42 – Practical Barriers: AFP, Ultrasound, Radiology Reports0:24:02 – Shift Toward Blood-Based Surveillance0:26:01 – How AFP-L3 and DCP Are Used in Practice0:27:39 – Rising AFP, Imaging Strategy & Broader Trend to Blood Tests0:28:27 – Guidelines vs Real-World Practice0:29:37 – Closing Thoughts on Guidelines & Early Detection

First Baptist Church BG
Strength Within Frailty | 2 Corinthians 4:1–18

First Baptist Church BG

Play Episode Listen Later Feb 2, 2026 26:02


Feeling frail? The greatest Source of strength is available to you.   ---    Have you ever felt powerless? I have, and it's a horrible feeling. I'm used to being able typically to figure out the challenges that come my way. Sometimes, though, nothing seems to work. As we walk together through 2 Corinthians, we're going to see what true power really looks like. We're going to see in various ways that God's power is made perfect in our weakness, and we're going to see why Paul would say “when I am weak, then I am strong.”   Sermon Notes: http://bible.com/events/49556238  Submit a Question: bit.ly/BeyondSundayQuestions

Optimal Health Daily
3233: Strength Training: The Ultimate Fountain of Youth by Eric Bach of Bach Performance on Lifelong Fitness Power

Optimal Health Daily

Play Episode Listen Later Dec 23, 2025 12:22


Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3233: Eric Bach makes a compelling case for strength training as the most powerful tool to extend not just lifespan but healthspan. By preserving muscle mass, boosting metabolism, and improving mobility, intelligent resistance training can help you look, feel, and move like someone decades younger, no miracle diets or gimmicks required. Read along with the original article(s) here: https://bachperformance.com/strength-training-the-ultimate-fountain-of-youth/ Quotes to ponder: "Lifting weights isn't about being jacked, ‘bro. It's about living longer and healthier, ‘bro." "Getting stronger in the gym is the compound interest of training. The more you put in earlier, the more wealth you'll accumulate over time." "Building a foundation of strength improves your ability to build muscle." Episode references: Frailty and adverse health outcomes study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2465752/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Intelligent Medicine
Intelligent Medicine Radio for December 20, Part 1: Cocoa Ingredient that Slows Aging

Intelligent Medicine

Play Episode Listen Later Dec 22, 2025 43:00


Popular media leverage weak study to criticize RFK Jr.'s rethink of standard recommendations for saturated fat avoidance; Poor quality plant-based diets hike cardio risk; A listener complains his lp(a) is going up with age despite his healthy diet, lifestyle; Scientists pinpoint cocoa ingredient that slows aging; Berry proanthocyanidins preserve brain power; Tattooing may promote inflammation, undermine immunity.

Intelligent Medicine
Intelligent Medicine Radio for December 6, Part 1: War Against Ultra-Processed Foods

Intelligent Medicine

Play Episode Listen Later Dec 8, 2025 42:59


Intelligent Medicine
Leyla Weighs In: Enhancing Strength--Vitamin C & E's Role in Muscle Health for Seniors

Intelligent Medicine

Play Episode Listen Later Dec 5, 2025 24:18


Nutritionist Leyla Muedin details a study on the effects of vitamins C and E supplementation in older women with sarcopenia. The study, published in the journal Medicine, found that combining 1000 mg of vitamin C and 335 mg of vitamin E with a 12-week resistance training program significantly improved muscle mass, strength, and certain blood parameters compared to a placebo group. The benefits were attributed to the alleviation of oxidative stress and inflammation. Leyla underscores the importance of adequate animal protein intake to optimize resistance training outcomes.

American Hauntings Podcast
Frailty

American Hauntings Podcast

Play Episode Listen Later Dec 2, 2025 74:03 Transcription Available


In the past on this podcast, we have often asked the question of whether a monster is born or are they made? This might be the episode that finally answers that question. The story that follows suggests that monsters are NOT born; they're made – often by the very people who should protect them.Have a question or comment? Text us on the Haunt Line @ 217-791-7859New Facebook page - https://www.facebook.com/troytaylorodditiesCheck out our updated website and sign up for our newsletter at AmericanHauntingsPodcast.comWant an episode every week, plus other awesome perks and discounts? Check out our Patreon pageFind out merch at AmericanHauntingsClothing.comFollow us on Twitter @AmerHauntsPod, @TroyTaylor13, @CodyBeckSTLFollow us on Instagram @AmericanHauntingsPodcast, @TroyTaylorgram, @CodyBeckSTLThis episode was written by Troy TaylorProduced and edited by Cody BeckOur Sponsors:* Check out CBDfx and use my code HAUNTINGS for a great deal: https://cbdfx.com* Check out Shopify: https://shopify.com/hauntings* Check out Uncommon Goods: https://uncommongoods.com/HAUNTINGSSupport this podcast at — https://redcircle.com/american-hauntings-podcast/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Wisdom-Trek ©
Day 2730 Wisdom Nuggets – Psalm 90:10-17 – Daily Wisdom

Wisdom-Trek ©

Play Episode Listen Later Nov 12, 2025 9:55 Transcription Available


Welcome to Day 2730 of Wisdom-Trek. Thank you for joining me. This is Guthrie Chamberlain, Your Guide to Wisdom Day 2760 – Wisdom Nuggets – Psalm 90:10-17 – Daily Wisdom Wisdom-Trek Podcast Script - Day 2730 Welcome to Wisdom-Trek with Gramps! I am Guthrie Chamberlain, and we are on Day 2730 of our Trek. The Purpose of Wisdom-Trek is to create a legacy of wisdom, to seek out discernment and insights, and to boldly grow where few have chosen to grow before. The title of today's Wisdom-Trek is: The Wisdom to Number Our Days – A Prayer for Satisfaction and Significance Today, we reach the conclusion of the oldest psalm in the Psalter, Psalm Ninety, also known as the timeless Prayer of Moses, covering its remaining verses, ten through seventeen, in the New Living Translation. In our last conversation, we explored the sobering first half of this psalm. Moses established the immense chasm between the eternal God—our “home” and refuge who predates the mountains—and the transient life of man, who vanishes like a “dream” or “grass” that is withered by evening. We acknowledged that our fleeting years are often spent under the cloud of God's righteous anger against sin, as He sets our “secret sins in the light of [His] presence” (Psalm Ninety, verse eight). Now, Moses moves from somber theological reflection to a fervent, practical prayer. Recognizing the brevity and the sorrow of a life lived under divine displeasure, he prays for wisdom, mercy, and ultimate significance. This concluding segment is the mature response to our mortality: since our days are numbered, how can we ensure they are counted for something eternal? So, let us open our hearts to this ancient and vital prayer, learning how to redeem the time God has given us. The first segment is: The Frailty of Life and the Plea for Wisdom Psalm Ninety: verses ten through twelve Seventy years are given to us! Some even live to eighty. But even the best years are filled with pain and trouble; soon they disappear, and we fly away. Who can comprehend the power of your anger? Your wrath is as awesome as the fear you deserve. Teach us to realize the brevity of life, so that we may grow in wisdom. Moses begins by stating the typical limit of human lifespan, a stark number based on his long experience with the dying generation in the wilderness: "Seventy years are given to us! Some even live to eighty." This lifespan, while a gift, is often limited, but Moses acknowledges that longer life isn't always better: "But even the best years are filled with pain and trouble; soon they disappear, and we fly away." This speaks to a universal truth: even the healthiest and most prosperous years have their share of hardship—a reality that the ancient Israelites knew...

Dr. Joseph Mercola - Take Control of Your Health
Walking Outdoors Reduces Frailty in Older Adults

Dr. Joseph Mercola - Take Control of Your Health

Play Episode Listen Later Nov 7, 2025 6:22


Frailty, once thought to be irreversible, is now recognized as a condition that can be improved through consistent outdoor movement, restoring strength, balance, and independence in older adults Research from Canada's GO-OUT studies shows that even simple walking programs — whether guided park walks or weekly reminders — measurably reduce frailty and boost mobility in as little as 10 weeks Confidence, not just time spent walking, proved to be the strongest predictor of improvement, as older adults who practiced in supportive outdoor groups felt safer and more capable continuing on their own A Hong Kong trial found that pairing a smartphone app with outdoor fitness equipment helped older adults stay active, build exercise confidence, and improve mental well-being far beyond structured classes You don't need a gym to rebuild vitality — start with short, daily walks outdoors, add small balance or strength challenges, and work toward one hour a day to strengthen muscles, circulation, and confidence naturally

They Walk Among Us - UK True Crime
Force & Frailty / Donald Burgess / PC Stephen Smith & PC Rachel Comotto

They Walk Among Us - UK True Crime

Play Episode Listen Later Nov 5, 2025 53:21


In the quiet corridors of a seaside care home, on an ordinary weekday afternoon, a 92-year-old man sat confused in his wheelchair, gripping a butter knife he'd been using to eat his lunch. Within minutes, two police officers would arrive at his door after being alerted that it was vital for them to attend the scene quickly, as someone's life had been threatened…*** LISTENER CAUTION IS ADVISED *** This episode was researched and written by Eileen Macfarlane.Edited by Joel Porter at Dot Dot Dot Productions.Script editing, additional writing, illustrations and production direction by Rosanna FittonNarration, additional audio editing and mixing, and script editing by Benjamin Fitton.To get early ad-free access, including Season 1, sign up for They Walk Among PLUS, available from Patreon or Apple Podcasts.More information and episode references can be found on our website https://theywalkamonguspodcast.comMUSIC: Falling Skies by Louis Lion Darker Days by Alternate Endings Pursuit Of Wonder by Caleb Etheridge Road To Nowhere by Caleb Etheridge To What End by Caleb Etheridge Rampant by CJ0 Bane by Cody Martin Far From Home by Cody Martin Final Moments by Cody Martin Outer Rim by Cody Martin Rising Sun by Colossus Distant Water by Chelsea McGough Siege by Hill Creeper by Hill The Plot Thickens by Joshua Spacht Ancient Ground by Moments The Way Back by Moments Onward by Chelsea McGough SOCIAL MEDIA: https://linktr.ee/TheyWalkAmongUsSupport this show http://supporter.acast.com/theywalkamongus. Hosted on Acast. See acast.com/privacy for more information.