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Stoney and TJ Lang (via a conversation with Valenti) offered two different hypotheses as to the plan (or lack thereof) the Lions are executing this offseason.
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Chuck Todd surveys a political landscape where multiple crises are converging on the Trump administration simultaneously — and none of them are going well. The Iran war, which Chuck reiterates is a war of choice, appears to be devouring Trump's presidency: the administration burned through nearly $6 billion in munitions in just two days, is sending contradictory messages of reassurance and escalation that appear designed to manipulate markets, and seems to be operating entirely by the seat of its pants. He warns that asymmetric warfare has never gone well for the United States, that energy markets are in turmoil as Iran deliberately tries to inflict economic pain, that the threat of stagflation and energy shortages is very real, and that Trump's threat to use the Fed to shape oil markets has alarmed economists. He argues that if Trump could undo the war he would — but this won't be Venezuela 2.0, because there's no opposition on the ground to coordinate with, you can't change a regime without boots on the ground that Trump won't commit, and if the regime simply survives, that counts as victory for Iran. Meanwhile, Trump naively buys Putin's claim that Russia isn't helping Iran with targeting, and that new polling shows a majority of Americans oppose the war — with MAGA influencers notably against it even as older rank-and-file supporters stick with Trump. Beyond Iran, Chuck hits the Ticketmaster settlement as proof that Trump talks a big populist game but the lobbyists always win, warns that a partial DHS shutdown risks snarling air travel and punishing the flying public while ICE has already been funded, and cautions Democrats not to overplay their hand on the shutdown. Then, John Adams, editor of the Montana Free Press, joins the Chuck Toddcast to make the case that local journalism has been in crisis — and that saving it might be one of the most important things Americans can do for their democracy. Adams is on the show to promote Local News Day on April 9th, a nationwide effort involving 700 local newsrooms aimed not at fundraising but at spreading awareness. He traces the origin story of the Montana Free Press back to his appearance in the documentary "Dark Money", a story about outside money quietly trying to buy Montana politics at the local level with zero disclosure — and the journalists best positioned to expose it were losing their jobs. Adams argues the economics of local news changed drastically as advertising revenue collapsed and audiences became hypnotized by social media and smartphones, but that the need and appetite for local reporting never went away. The conversation turns to the deeper consequences of local news deserts: the loss of trusted community voices created a vacuum that bred distrust in the national press, because people no longer had local "character references" — journalists they knew and saw at the grocery store — to anchor their understanding of how media works. Adams warns that the rise of AI-generated misinformation makes reliable local sources more important than ever, noting that while younger people tend to be savvier at spotting junk online, older generations are particularly vulnerable. They close by noting that strong local news doesn't just serve democracy — it helps local businesses target customers, creating an economic ecosystem that benefits everyone — and that journalism ultimately has to reach enough people to really matter, which is exactly what Local News Day at localnewsday.org is designed to help make possible. Finally, on the day of the Mississippi primaries, Chuck gives his ToddCast Top 5 All-Time statewide races in Mississippi and answers listeners’ questions in the “Ask Chuck” segment. Go to https://zbiotics.com/CHUCKTODDCAST and use CHUCKTODDCAST at checkout for 15% off any first time orders of ZBiotics probiotics.” Protect your family with life insurance from Ethos. Get up to $3 million in coverage in as little as 10 minutes at https://ethos.com/chuck. Application times may vary. Rates may vary. Refresh your wardrobe with Quince. Go to https://Quince.com/chuck for free shipping on your order and 365-day returns. Link in bio or go to https://getsoul.com & enter code TODDCAST for 30% off your first order. American Finance Disclaimer: NMLS 182334, nmlsconsumeraccess.org. APR for rates in the 5s start at 6.196% for well qualified borrowers. Call 866-885-1081, for details about credit costs and terms. Or https://apply.americanfinancing.net/thechucktoddcast Timeline: (Timestamps may vary based on advertisements) 00:00 Chuck Todd’s introduction 00:30 Despite runoff, Dems shouldn’t get hopes up for MTG’s district 01:30 Bennie Thompson survives primary challenge in Mississippi 07:15 War of choice in Iran could devour Trump’s presidency 08:00 Administration messaging appears to be manipulating markets 09:30 We got both a message of reassurance and escalation on Monday 10:30 Administration seems to be operating by the seat of their pants 12:00 Administration has eroded trust in institutions for years 13:00 Eventually markets will stop reacting to government statements 13:30 Administration burned through nearly $6B in munitions in two days 14:30 Asymmetric warfare has never gone well for the United States 15:15 Energy markets are in turmoil, Iran wants to create economic pain 16:00 Threat of stagflation & energy shortages are very real 16:45 Trump threatens to use the fed to shape oil markets, alarming economists 17:30 Partial shutdown of DHS agents risks snarling air travel 18:30 When do Dems declare victory on partial shutdown? Noem was fired 19:45 ICE has already been funded. Shutdown punishes the flying public 20:30 Democrats need to be careful not to overplay their hand in shutdown 21:00 If Trump could undo the war, he would. It won’t be Venezuela 2.0 22:15 We’ve always paid to rebuild countries we’ve bombed 23:00 If the regime survives, that’s victory for Iran 24:15 Can’t change regime without boots on the ground, which Trump won’t do 25:15 There’s no opposition on the ground to coordinate with 26:00 Trump buys story from Putin that Russia isn’t assisting Iran w/targeting 26:45 U.S. using up munitions headed to Ukraine is best case for Russia 28:00 DOJ agrees to incredibly friendly settlement with Ticketmaster 28:45 Live Nation lobbyists went straight to Trump, then deal is cut 29:15 Trump talks a big game on populism, but the lobbyists always win 30:45 Young independents hate corporate power & Trump sides with corporations 31:30 New polling shows majority of Americans are against war with Iran 32:15 Older voters continue to be strongest supporters of Trump & war 33:00 MAGA influencers are against war, but rank & file support Trump 42:30 John Adams (Montana Free Press) joins the Chuck ToddCast 43:15 The importance of local news & purpose of Local News Day, April 9th 45:45 Why create Local News Day? 46:45 The crisis with local news isn’t new, been happening for years 48:00 It’s easier to get international news than news from your community 49:00 The need and appetite for local news has never gone away 50:15 Local news has become en vogue like a local craft beer 52:15 People embrace their local identity 54:45 Origin story of the Montana Free Press 55:15 “Dark Money” documentary about fight against Montana copper barons 57:30 Big outside money was trying to buy Montana politics at the local level 59:45 None of the outside money was disclosed 1:00:30 John lost his reporting job during the 2015 legislative session 1:02:30 Three of the most experienced local journalists were jobless 1:03:00 MFP founded on principle that local journalism is essential as a nonprofit 1:04:45 Economics of local news changed drastically, made newspapers expensive 1:06:30 Audiences are highly distracted by social media & smartphones 1:08:00 We need good new sources of information to combat misinfo from AI 1:09:15 Younger people are savvier online, older generations struggle with AI 1:11:00 It’s easier to trust local news sources because they’re in your community 1:11:45 Journalists have to almost “sell” their info for people to see it 1:14:00 It’s important to report on what your audience cares about 1:15:30 AP reporter in Montana was attacked and then the reporter was doxxed 1:17:45 Loss of local news character references created distrust in national press 1:19:00 Importance of local “service journalism” 1:22:30 Recreating the equivalent of morning drive news radio as a podcast 1:23:15 Using google trends questions to help inform your journalism 1:24:30 Algorithms only give people what they want, not what they need to know 1:25:15 Local news at its best reflects what the community cares about 1:26:15 Localnewsday.org is where people can find ways to help & connect 1:28:00 The better local news does, the better local businesses can target customers 1:29:00 700 local newsrooms are taking part in Local News Day 1:30:00 Goal of Local News Day isn’t to raise money, it’s to spread awareness 1:33:00 Journalism has to reach enough people to really matter 1:35:00 Take action on April 9th to support local news 1:35:30 ToddCast Top 5 All-Time Mississippi statewide campaigns 1:40:00 #1 1959 gubernatorial 1:42:00 #2 1978 senate race 1:43:30 #3 1978 gubernatorial 1:45:00 #4 1999 gubernatorial 1:47:00 #5 2014 senate Republican primary 1:49:30 Honorable mentions 1:52:30 Ask Chuck 1:52:45 Do you have a Top 5 list coming for New Jersey? 1:56:00 How do we keep getting into wars without declaration from congress? 1:59:30 What will it take for the U.S. to rebuild trust on the world stage? 2:03:00 Will abortion become an issue in 2028 or has Dobbs taken it off the table? 2:06:30 Should Democrats break norms to prevent authoritarianism?See omnystudio.com/listener for privacy information.
Chuck Todd surveys a political landscape where multiple crises are converging on the Trump administration simultaneously — and none of them are going well. The Iran war, which Chuck reiterates is a war of choice, appears to be devouring Trump's presidency: the administration burned through nearly $6 billion in munitions in just two days, is sending contradictory messages of reassurance and escalation that appear designed to manipulate markets, and seems to be operating entirely by the seat of its pants. He warns that asymmetric warfare has never gone well for the United States, that energy markets are in turmoil as Iran deliberately tries to inflict economic pain, that the threat of stagflation and energy shortages is very real, and that Trump's threat to use the Fed to shape oil markets has alarmed economists. He argues that if Trump could undo the war he would — but this won't be Venezuela 2.0, because there's no opposition on the ground to coordinate with, you can't change a regime without boots on the ground that Trump won't commit, and if the regime simply survives, that counts as victory for Iran. Meanwhile, Trump naively buys Putin's claim that Russia isn't helping Iran with targeting, and that new polling shows a majority of Americans oppose the war — with MAGA influencers notably against it even as older rank-and-file supporters stick with Trump. Beyond Iran, Chuck hits the Ticketmaster settlement as proof that Trump talks a big populist game but the lobbyists always win, warns that a partial DHS shutdown risks snarling air travel and punishing the flying public while ICE has already been funded, and cautions Democrats not to overplay their hand on the shutdown. Finally, on the day of the Mississippi primaries, Chuck gives his ToddCast Top 5 All-Time statewide races in Mississippi and answers listeners’ questions in the “Ask Chuck” segment. Go to https://zbiotics.com/CHUCKTODDCAST and use CHUCKTODDCAST at checkout for 15% off any first time orders of ZBiotics probiotics.” Protect your family with life insurance from Ethos. Get up to $3 million in coverage in as little as 10 minutes at https://ethos.com/chuck. Application times may vary. Rates may vary. Refresh your wardrobe with Quince. Go to https://Quince.com/chuck for free shipping on your order and 365-day returns. Link in bio or go to https://getsoul.com & enter code TODDCAST for 30% off your first order. American Finance Disclaimer: NMLS 182334, nmlsconsumeraccess.org. APR for rates in the 5s start at 6.196% for well qualified borrowers. Call 866-885-1081, for details about credit costs and terms. Or https://apply.americanfinancing.net/thechucktoddcast Timeline: 00:00 Chuck Todd’s introduction 00:30 Despite runoff, Dems shouldn’t get hopes up for MTG’s district 01:30 Bennie Thompson survives primary challenge in Mississippi 07:15 War of choice in Iran could devour Trump’s presidency 08:00 Administration messaging appears to be manipulating markets 09:30 We got both a message of reassurance and escalation on Monday 10:30 Administration seems to be operating by the seat of their pants 12:00 Administration has eroded trust in institutions for years 13:00 Eventually markets will stop reacting to government statements 13:30 Administration burned through nearly $6B in munitions in two days 14:30 Asymmetric warfare has never gone well for the United States 15:15 Energy markets are in turmoil, Iran wants to create economic pain 16:00 Threat of stagflation & energy shortages are very real 16:45 Trump threatens to use the fed to shape oil markets, alarming economists 17:30 Partial shutdown of DHS agents risks snarling air travel 18:30 When do Dems declare victory on partial shutdown? Noem was fired 19:45 ICE has already been funded. Shutdown punishes the flying public 20:30 Democrats need to be careful not to overplay their hand in shutdown 21:00 If Trump could undo the war, he would. It won’t be Venezuela 2.0 22:15 We’ve always paid to rebuild countries we’ve bombed 23:00 If the regime survives, that’s victory for Iran 24:15 Can’t change regime without boots on the ground, which Trump won’t do 25:15 There’s no opposition on the ground to coordinate with 26:00 Trump buys story from Putin that Russia isn’t assisting Iran w/targeting 26:45 U.S. using up munitions headed to Ukraine is best case for Russia 28:00 DOJ agrees to incredibly friendly settlement with Ticketmaster 28:45 Live Nation lobbyists went straight to Trump, then deal is cut 29:15 Trump talks a big game on populism, but the lobbyists always win 30:45 Young independents hate corporate power & Trump sides with corporations 31:30 New polling shows majority of Americans are against war with Iran 32:15 Older voters continue to be strongest supporters of Trump & war 33:00 MAGA influencers are against war, but rank & file support Trump 37:45 Take action on April 9th to support local news 38:15 ToddCast Top 5 All-Time Mississippi statewide campaigns 42:45 #1 1959 gubernatorial 44:45 #2 1978 senate race 46:15 #3 1978 gubernatorial 47:45 #4 1999 gubernatorial 49:45 #5 2014 senate Republican primary 52:15 Honorable mentions 55:15 Ask Chuck 55:30 Do you have a Top 5 list coming for New Jersey? 58:45 How do we keep getting into wars without declaration from congress? 1:02:15 What will it take for the U.S. to rebuild trust on the world stage? 1:05:45 Will abortion become an issue in 2028 or has Dobbs taken it off the table? 1:09:15 Should Democrats break norms to prevent authoritarianism?See omnystudio.com/listener for privacy information.
It's In the News, a look at the top headlines and stories in the diabetes community. This week's top stories: Stem Cell Islet Therapy Partnership, "Lyla's Law" Type 1 Testing Debate, Patient-Led Insulin Dosing for Gestational Diabetes, $3 Semaglutide Manufacturing, FDA GLP-1 Compounding Crackdown Announcing Community Commericals! Learn how to get your message on the show here. Learn more about studies and research at Thrivable here Please visit our Sponsors & Partners - they help make the show possible! Omnipod - Simplify Life All about Dexcom All about VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com transcript with links: Welcome! I'm your host Stacey Simms and this is an In The News episode.. where we bringing you the top diabetes stories and headlines happening now. A reminder that you can find the sources and links and a transcript and more info for every story mentioned here in the show notes. I am definitely feeling better – that lingering cold is gone – but whew still recovering from non stop travel for the past five weeks. I have a great strech of time her at home, then going to Vegas for Brekathorugh T1D at the end of the month and we have two club 1921 events in April – Atlanta and Philly. Before we jump into the news – I need your community commercials! These have been a lot of fun, I announced them late last year – your voice on the show. All the instructions it's very easy in the show notes. Okay.. our top story this week: XX A biotech company developing stem-cell treatments for type 1 diabetes has announced a new research partnership aimed at improving the survival of transplanted insulin-producing cells. NewcelX, a clinical-stage company based in Switzerland, said it will work with Eledon Pharmaceuticals to study a combination approach. The goal is to help transplanted cells survive longer in the body by reducing the immune response that often leads to transplant rejection. If successful, the strategy could support longer-lasting islet cell replacement and move the therapy closer to becoming a functional treatment for people with type 1 diabetes. However, the companies have not yet released any safety or effectiveness data on the combination treatment, and financial details of the partnership were not disclosed. The research agreement is focused on exploring whether combining stem-cell-derived islets with targeted immune therapy can lead to longer-lasting cell transplants and improved outcomes for people with type 1 diabetes. https://www.stocktitan.net/news/ELDN/newcel-x-announces-strategic-collaboration-with-eledon-d10l1vqdofls.html XX Debate this week in the UK on whether testing for type 1 diabetes should become mandatory when children present with symptoms. The Westminster Hall debate, scheduled for 9 March, will consider calls for routine testing of babies, toddlers and young children who show signs associated with the condition. It follows a petition backing the move, dubbed 'Lyla's Law', which passed 121,000 signatures in December 2025. The campaign was launched by John Story after his two-year-old daughter, Lyla, died from diabetic ketoacidosis (DKA) on 3 May 2025, 16 hours after being diagnosed with tonsillitis. https://www.nursinginpractice.com/clinical/diabetes-and-endocrinology/diabetes-community-urged-to-call-on-mps-to-attend-lylas-law-debate/ XX A new study suggests that people with gestational diabetes who adjust their own insulin doses may reach healthy blood sugar levels faster than those whose doses are adjusted by clinicians. Half of the participants were assigned to adjust their own insulin doses using a simple rule: increase the dose by two units if fasting blood glucose was above 95 mg/dL, decrease it by two units if it dropped below 70 mg/dL, and keep the same dose if levels fell in between. The other half had their insulin adjusted by clinicians through weekly reviews. By the end of pregnancy, both groups had similar average fasting glucose levels before delivery: about 89 mg/dL in the patient-led group and 90 mg/dL in the clinician-led group. However, those adjusting their own insulin reached their blood sugar targets more quickly, averaging 1.8 weeks compared with 2.5 weeks for those managed by clinicians. The study also found lower risks of certain complications among the patient-led group. https://www.medscape.com/viewarticle/self-insulin-dosing-leads-control-gestational-diabetes-2026a1000729 XX A blockbuster anti-obesity and diabetes drug could cost as little as $3 per month to manufacture once it goes off patent later this month, researchers said Friday, providing a major opportunity to boost health in low and middle-income countries. Semaglutide, the active molecule in Novo Nordisk's Ozempic and Wegovy will lose patent protection in countries such as Brazil, China, and India later this month, and researchers identified 150 countries where it was never patented. These researchers estimated it will cost as little as $3 to produce a month's supply of semaglutide, which in its branded form sells for around $200 a month in the United States. Another of the study's authors, Professor Francois Venter at the University of Witwatersrand in South Africa, said drugs to treat HIV, TB, malaria, and hepatitis are now available at prices close to production costs but still sufficient for generic manufacturers to operate. https://www.sciencealert.com/weight-loss-drugs-could-cost-just-3-a-month-to-make-as-patents-end XX Here in the US the FDA is stepping up its efforts to combat widespread GLP-1 drug compounding. In its latest offensive, the agency has unleashed a fresh set of 30 warning letters targeting telehealth companies it says make "false or misleading" claims about compounded versions of popular obesity drugs. The FDA says Compounded drugs can be important for overcoming shortages or meeting unique patient needs—but compounders should not try to compound drugs in a way that circumvents FDA's approval process." https://www.fiercepharma.com/pharma/fda-ramps-crackdown-glp-1-drug-compounders-fresh-batch-30-warning-letters XX Check your infusion sets for an issue: Unomedical, a subsidiary of Convatec and a supplier of insulin infusion sets to diabetes tech firms, has received a warning letter from the FDA. Inspectors raised concerns with leaking infusion sets, following a regulatory assessment of Unomedical's facility in Reynosa, Mexico, last summer. Unomedical supplies infusion sets to insulin pump makers including Medtronic, Tandem Diabetes Care and Beta Bionics. In a Feb. 3 statement, Convatec said the letter focuses on reporting procedures and quality protocols and does not place restrictions on producing, marketing or distributing any of Unomedical's products. Unomedical told the FDA in its responses that it plans to conduct a retrospective review of complaints involving serious injury or death by January and conduct additional training on complaint handling by May. https://www.medtechdive.com/news/fda-warns-insulin-infusion-set-maker-unomedical-over-leaks-mishandled-comp/813503/ XX Nearly four in ten people with type 2 diabetes do not take their medications as prescribed, according to a new research review published in Diabetologia in November 2025. Researchers examined existing studies on medication adherence, including how often patients miss doses, why it happens, and what strategies may help. They estimated that about 38% of patients with type 2 diabetes are not fully adherent to their medications. Adherence rates vary depending on the type of medication. About 63% to 68% of patients take oral glucose-lowering drugs as directed, while adherence drops to 43% to 54% for injectable GLP-1 medications and 41% to 64% for insulin. Poor adherence can lead to serious consequences. One retrospective study cited in the review found that patients who consistently took their glucose-lowering medications had a 31% lower risk of hospitalization or emergency department visits. The review also highlighted ways to improve adherence. Simplifying medication routines can help, such as using fixed-dose combination pills, which combine multiple drugs into a single tablet. Studies show these combinations are linked to better adherence and improved blood sugar control. Pharmacists can also play an important role by providing education, reviewing medications, setting up reminders, and helping patients organize their treatment plans. The researchers noted that support should be tailored to each patient. Older adults may benefit from simpler systems and caregiver support, while younger patients may respond better to digital tools like app-based reminders. The authors also found that measuring adherence is challenging and recommend using multiple methods, such as pharmacy records, patient interviews, and objective tests when possible. Overall, the review concludes that personalized, multi-step approaches lasting at least three months are most effective in helping people with type 2 diabetes stay on track with their medications. https://www.pharmacytimes.com/view/type-2-diabetes-medication-adherence-rates-remain-low-and-pharmacists-can-help XX New clinical trial shows metformin does not directly reverse insulin resistance in people with type 1 diabetes. Instead, it lowers the total amount of insulin required to keep blood glucose levels within the recommended range. The findings, published in Nature Communications, challenge long-held assumptions about how metformin works in type 1 diabetes. The results may help physicians refine treatment strategies and reduce the daily demands placed on people who rely solely on insulin therapy. "Insulin resistance is a growing problem in type 1 diabetes. Not only does it make regulating blood sugar levels difficult, but it is an underappreciated risk factor for heart disease, which is one of the biggest causes of health complications and deaths in those with type 1 diabetes," says Dr. Jennifer Snaith, endocrinologist and co-lead of the study. https://scitechdaily.com/groundbreaking-trial-reveals-unexpected-benefit-of-metformin-in-type-1-diabetes/ Tech news ahead, including updates from Sensonics, Dexcom & Tandem.. right after this…. Back ot the wnews.. XX Sensonics shares that it's secured FDA investigational device exemption (IDE) for its self-powered, battery-enabled Gemini sensor. It enrolled the first patients in the IDE trial and expects to complete that in the second half of 2026. Gemini builds on the implanted CGM to put the transmitter under the skin as well as the sensor. https://www.drugdeliverybusiness.com/senseonics-q4-2025-ide-gemini-cgm/ XX Medtronic Diabetes is now officially MiniMid, a stand alone public company. Medtronic acquired MiniMed 25 years ago announed last May that it would spin its diabetes business off. In their statement the company points out that MiniMed is the only diabetes tech company to sell both insulin pumps and continuous glucose monitors. https://www.investing.com/news/stock-market-news/medtronics-diabetes-unit-minimed-valued-at-53-billion-as-shares-fall-in-nasdaq-debut-4547518 XX Kevin Sayer heads back to Dexcom.. The former CEO is back in his position as executive chair of the Board, he'd stepped away for a medical leave. Dexcom (Nasdaq:DXCM) announced today in an SEC filing that former CEO Kevin Sayer has returned from his leave of absence. Sayer's return to the board comes just days after Dexcom announced a new board member. Last week, the company announced that it added Google SVP, Platforms and Devices, Rick Osterloh, to its board as well. https://www.drugdeliverybusiness.com/kevin-sayer-returns-dexcom-board-chair/ SAN DIEGO - DexCom, Inc. (NASDAQ:DXCM) announced the appointment of Rick Osterloh to its Board of Directors, effective today, according to a press release statement. Osterloh serves as Senior Vice President, Platforms & Devices at Google, where he oversees Android, Google Play, Chrome, and Google's hardware portfolio including Pixel phones, Google Nest devices, and Fitbit wearables. He has held this position since 2016. https://www.investing.com/news/company-news/dexcom-appoints-google-executive-rick-osterloh-to-board-93CH-4529662 XX Sequel Med Tech announced broad national availability of its twiist™ Automated Insulin Delivery (AID) System powered by Tidepool. After U.S. FDA clearance in 2024 and a controlled launch to optimize the twiist experience, the system is now fully available nationwide. The release says: Built on Sequel's proprietary iiSure™ Technology, the system enables earlier detection of delivery issues, alerting users to blockages up to nine times faster than other AID systems1, potentially reducing the risk of unexplained high glucose and giving you time to take action before experiencing severe high blood sugar or DKA2. Designed to expand access to automated insulin delivery, twiist is available through pharmacy channels with a flexible access model, XX Tandem Diabetes Care's Mobi automated insulin delivery system is now available with Android devices. In November, Tandem announced that it received FDA approval for the Android version of its Mobi mobile app. The pump, which pairs with Tandem's Control-IQ+ algorithm, previously worked with iOS software. At the time of the clearance, it said it would commence a limited rollout before the full launch — now underway — this year. Tandem launched Mobi in the U.S. in February 2024. It initially received FDA clearance for people with diabetes ages six and up in July 2023. The system then received expanded clearance for pediatric indications in April 2024, then later won CE mark in May 2025. Mobi features a 200-unit insulin cartridge and an on-pump button to provide an alternative to phone control for insulin boluses. It comes in at less than half the size of the flagship Tandem pump system, the t:slim X2 pump. Mobi can fit in a coin pocket, clip to clothing or go on the body with an adhesive sleeve. https://www.drugdeliverybusiness.com/tandem-diabetes-care-launches-mobi-android/
Elevating Customer Support Teams with Smart AI Integration Shep interviews Sam Wilson, Chief Executive Officer of 8x8. He talks about the evolving role of AI in business communications and why customer experience professionals should be recognized as revenue generators rather than cost centers. This episode of Amazing Business Radio with Shep Hyken answers the following questions and more: What impact does self-service technology have on customer satisfaction? How can AI self-service and human support work together effectively? What drives customers to switch companies due to poor self-service? What makes customers more forgiving of mistakes by human agents than AI systems? Why should businesses view customer service as a revenue center rather than a cost center? Top Takeaways: Relying exclusively on self-service or automation is not enough. Customers should always have a way to speak to a real person when technology can't meet their needs. AI-powered solutions work well for routine requests, but there must be a seamless failover to a human agent when things get complicated or the customer is dissatisfied. California has enacted a law requiring companies to offer a quick, clear option for customers to connect with a human representative if their self-service solutions, often powered by AI, don't deliver satisfactory results. AI and automation in customer service are growing, reducing the volume of easy, repetitive cases handled by humans. More complex and sensitive issues are go to human agents and as a result, today's customer support agents are required to handle more complex issues and provide a higher level of expertise and empathy, making them specialists rather than agents. The customer support department is a revenue center. Delivering consistently excellent experiences leads to higher retention rates, repeat business, and positive reviews. Customers of different ages have distinct preferences for how they interact with support. Older customers lean towards phone support, while younger generations prefer chat or digital channels. But both demographics still want the assurance of being able to call a support agent if their problem isn't resolved online. Leading companies like Amazon have set the standard for customer support by combining AI for routine tasks with proactive escalation to human agents when needed. They have created a seamless customer experience by enabling quick, easy connection with knowledgeable support agents and avoiding the need to repeat themselves to get their issue resolved. Regular customers sustain and grow a company. Regular customers drive steady revenue and are typically the brand's biggest advocates. The future of customer service lies in integrating effective technology with empowered employees. Companies that invest in effective digital solutions and well-trained customer specialists are best positioned to create positive experiences, adapt to customer preferences, and succeed in a competitive marketplace. Effective customer support isn't rocket science. The technology exists today to empower both businesses and consumers with choice and flexibility, and it is more affordable than it was five or ten years ago. The real differentiator is the willingness to implement these solutions and put the customer's needs first. Quote: "One of the great mistakes tech companies make is we talk too much about features and don't talk enough about our customers." About: Sam Wilson is the Chief Executive Officer of 8x8, with over 25 years of experience in finance, investment, and sales. He has held several key leadership roles at 8x8, including Chief Financial Officer and Chief Customer Officer. Shep Hyken is a customer service and experience expert, New York Times bestselling author, award-winning keynote speaker, and host of Amazing Business Radio. Learn more about your ad choices. Visit megaphone.fm/adchoices
Which Spurs players were older than ex gaffer, Ryan Mason? Who has actually won the PFA Player of the Year award? Why have so many Dutch footballers released rap albums? Which journalist did Eamo mug off? Listen on for all this and more football trivia drivel. Join our Patreon to access our back catalogue of over 80 episodes! Patreon.com/CareerWeGoExtraTimeGot a round you'd like us to try? Email: hello@careerwego.com Hosted on Acast. See acast.com/privacy for more information.
4. Headline: The Fatal Flight of the ItaliaGuest Author: Mark Piesing Summary:Piesing describes the 1928 Italia expedition, noting how political sabotage forced Nobile to use an older airship design. After reaching the North Pole, the vessel crashed into sea ice. Six men drifted away forever, while those remaining survived thanks to emergency supplies tossed from the envelope. (20)
Topics covered in this episode: Setting up a Python monorepo with uv workspaces cattrs: Flexible Object Serialization and Validation Learning to program in the AI age VS Code extension for FastAPI and friends Extras Joke Watch on YouTube About the show Sponsored by us! Support our work through: Our courses at Talk Python Training The Complete pytest Course Patreon Supporters Connect with the hosts Michael: @mkennedy@fosstodon.org / @mkennedy.codes (bsky) Brian: @brianokken@fosstodon.org / @brianokken.bsky.social Show: @pythonbytes@fosstodon.org / @pythonbytes.fm (bsky) Join us on YouTube at pythonbytes.fm/live to be part of the audience. Usually Monday at 11am PT. Older video versions available there too. Finally, if you want an artisanal, hand-crafted digest of every week of the show notes in email form? Add your name and email to our friends of the show list, we'll never share it. Brian #1: Setting up a Python monorepo with uv workspaces Dennis Traub The 3 things Give the Root a Distinct Name Use workspace = true for Inter-Package Deps Use importlib Mode for pytest Michael #2: cattrs: Flexible Object Serialization and Validation cattrs is a Swiss Army knife for (un)structuring and validating data in Python. A natural alternative/follow on from DataClass Wizard Converts to ←→ from dictionaries cattrs also focuses on functional composition and not coupling your data model to its serialization and validation rules. When you're handed unstructured data (by your network, file system, database, …), cattrs helps to convert this data into trustworthy structured data. Batteries Included: cattrs comes with pre-configured converters for a number of serialization libraries, including JSON (standard library, orjson, UltraJSON), msgpack, cbor2, bson, PyYAML, tomlkit and msgspec (supports only JSON at this time). Brian #3: Learning to program in the AI age Jose Blanca “I teach a couple of introductory Python courses and I've been thinking about which advice to give to my students, that are studying how to program for the first time. I have collected my ideas in these blog posts” Why learning to program is as useful as ever, even with powerful AI tools available. How to use AI as a tutor rather than a shortcut, and why practice remains the key to real understanding. What the real learning objectives are: mental models, managing complexity, and thinking like a software developer. Michael #4: VS Code extension for FastAPI and friends Enhances the FastAPI development experience in Visual Studio Code Path Operation Explorer: Provides a hierarchical tree view of all FastAPI routes in your application. Search for routes: Use the Command Palette and quickly search for routes by path, method, or name. CodeLens links appear above HTTP client calls like client.get('/items'), letting you jump directly to the matching route definition. Deploy your application directly to FastAPI Cloud from the status bar with zero config. View real-time logs from your FastAPI Cloud deployed applications directly within VS Code. Install from Marketplace. Extras Brian: Guido van Rossum interviews key Python developers from the first 25 years Interview with Brett Cannon Interview with Thomas Wouters Michael: IntelliJ IDEA: The Documentary | An origin story video Cursor Joined the ACP Registry and Is Now Live in Your JetBrains IDE What hyper-personal software looks like I'm doing in-person training again (limited scope): On-site, hands-on AI engineering enablement for software teams with Michael Joke: Saas is dead
Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-475 Overview: A prescribing cascade occurs when adverse effects of a medication are mistaken for a new condition and treated with additional drugs. Older adults experiencing polypharmacy are most at risk. The impact of prescribing cascades can be substantial, leading to falls, organ injury, unnecessary imaging and tests, and more. Join us as we explore how to recognize and prevent these harmful cascades in your patients. Episode resource links: Adrien O, Mohammad AK, Hugtenburg JG, et al. Prescribing cascades with recommendations to prevent or reverse them: a systematic review. Drugs Aging. 2023;40(12):1085-1100. doi:10.1007/s40266-023-01072-yPubMedGoogle ScholarCrossref Brath H, Mehta N, Savage RD, et al. What is known about preventing, detecting, and reversing prescribing cascades: a scoping review. J Am Geriatr Soc. 2018;66(11):2079-2085. doi:10.1111/jgs.15543PubMedGoogle ScholarCrossref Daunt R, McGettigan S, Kelly L, Curtin D, O'Mahony D. Detection of Potential Prescribing Cascades in Multimorbid Older Patients Hospitalised with Acute Illness-An Observational Prospective Prevalence Study. Drugs Aging. 2025;42(6):535-546. doi:10.1007/s40266-025-01201-9 Growdon ME, Tjota N, Campbell R, et al. Decision-Making and Downstream Outcomes of the Gabapentinoid-Diuretic Prescribing Cascade. JAMA Netw Open. 2025;8(12):e2545274. doi:10.1001/jamanetworkopen.2025.45274 McCarthy LM, Savage R, Dalton K, et al. ThinkCascades: a tool for identifying clinically important prescribing cascades affecting older people. Drugs Aging. 2022;39(10):829-840. doi:10.1007/s40266-022-00964-9PubMedGoogle ScholarCrossref O'Mahony, D., Cherubini, A., Guiteras, A.R. et al. STOPP/START criteria for potentially inappropriate prescribing in older people: version 3. Eur Geriatr Med 14, 625–632 (2023). https://doi.org/10.1007/s41999-023-00777-y Rochon, P.A., O'Mahony, D., Cherubini, A. et al. International expert panel's potentially inappropriate prescribing cascades (PIPC) list. Eur Geriatr Med 16, 1573–1584 (2025). https://doi.org/10.1007/s41999-025-01215-x Young EH, Pan S, Yap AG, Reveles KR, Bhakta K. Polypharmacy prevalence in older adults seen in United States physician offices from 2009 to 2016. PLoS One. 2021;16(8):e0255642. Published 2021 Aug 3. doi:10.1371/journal.pone.0255642 Guest: Susan Feeney, DNP, FNP-BC, NP-C Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.
To watch a video version of this podcast, click here: https://youtu.be/eK-WIS7inMUIn this episode, Reuben Saltzman and Tessa Murry talk with Steve Rogers, President of The Energy Conservatory (TEC), about the science behind home performance and why so many HVAC systems fall short of expectations. Steve shares TEC's journey from early prototypes to industry‑standard testing tools and explains how comfort, moisture, and efficiency issues often stem from the building envelope. The conversation dives into blower doors, airflow testing, duct leakage, furnace short‑cycling, restrictive filters, oversized systems, and the key measurements inspectors and homeowners commonly miss, offering practical insights for homeowners, inspectors, HVAC technicians, and building‑science enthusiasts alike.You can check out The Energy Conservatory website here: www.energyconservatory.comTakeawaysTEC manufactures tools that measure building airtightness, duct leakage, and airflow—core metrics for diagnosing home performance issues.Blower door testing became essential because leaky houses waste energy, cause comfort issues, and contribute to attic moisture problems.Early blower door prototypes were expensive and slow; TEC revolutionized the field with affordable, efficient models.Airflow is one of the hardest HVAC metrics to measure accurately; TEC's TruFlow Grid helps techs commission systems properly.Most furnaces and ACs are never tested for correct airflow after installation, which leads to early equipment failure and poor efficiency.High temperature rise = low airflow. This often causes the furnace to hit its high‑limit switch and shut off prematurely.Oversizing is rampant—many homes have furnaces 1.5–2× larger than needed, increasing noise, inefficiency, and comfort issues.Filter restrictions depend on pressure drop, not just MERV rating. Pleat depth and surface area matter more than the number printed on the label.3M Filtrete filters maintain reasonable pressure drops because they add pleats as MERV levels increase.The most important starting point in energy upgrades is a blower door test, not HVAC replacement.Older homes—especially balloon‑framed houses—are extremely leaky and need targeted air‑sealing.Complicated house shapes (L‑shaped, multi‑level splits, many dormers) are typically leakier than simple rectangular designs.Many contractors still do not measure airflow or static pressure, causing repeat callbacks and inefficiency.TEC's tools and apps help HVAC techs commission systems properly—reducing callbacks and improving system performance.Homeowners can access subsidized energy audits through utilities, often including blower door and infrared inspections.Chapters00:00 — Introduction and Guest Welcome02:00 — Steve's Background & The Origin of The Energy Conservatory05:00 — How Blower Doors Were Invented & Early Challenges08:00 — Engineers, Inventors & TEC's Company Culture11:00 — Advances in Airflow Testing: TruFlow Grid Explained15:00 — Why Airflow Is Critical for Furnace & AC Efficiency17:00 — Temperature Rise, High‑Limit Switches & Furnace Cycling20:00 — Common Installation Issues & What Inspectors Should Look For22:00 — The Truth About Furnace Filters & Pressure Drop26:00 — Oversizing Problems & Proper Equipment Matching31:00 — Why Most Homes Have Comfort Problems (and How to Fix Them)35:00 — Blower Door Testing as the First Step in Home Performance38:00 — Moisture, Attic Frost & Air Leakage Pathways41:00 — Styles of Homes That Tend to Be Leakier44:00 — Balloon Framing vs. Platform Framing47:00 — Why the Industry Changes Slowly & The Role of Training52:00 — How Homeowners Can Learn More & Access Energy Audits53:00 — Closing Tho
Welcome to Catholic Apologetics, led by Dr. Jim Dobbins, Author of Take My Hand: A Personal Retreat Companion. Just finished an RCIA program? This is the next stop on your faith journey. In these classes, we look at the different truths of Catholic doctrine and why we know they are true. We also discuss apologetics, spiritual growth, examine the liturgy of the Catholic Mass, and do scripture studies. Please encourage your friends to listen. I also encourage you to leave a comment about our podcasts. If you want the slides or any other documents for any class, just e-mail me at jhdphd@gmail.com and I will reply with the documents attached. If you wish, I will also add you to the class materials distribution list so that each time I send anything out for the class you will get it. If you are getting the podcast files from iTunes and would like to see the full set of available classes for download, you can see and download them all at http://yorked.podomatic.com. Older podcasts are now stored at a free podcast site at Podcast.com. The link to the podcasts there is: http://poddirectory.com/podcast/86506/dr-james-dobbins-catholic-apologetics We ask you to also consider going to http://yorked.podomatic.com and becoming a subscriber. It is free, helps our ratings, and thus helps us reach and help more people. This session is one of our discussions from our study of the Gospel of John. Please also let me know if there is a particular topic you would like to see addressed. skvEapm1rLLW8foJsII1
Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-475 Overview: A prescribing cascade occurs when adverse effects of a medication are mistaken for a new condition and treated with additional drugs. Older adults experiencing polypharmacy are most at risk. The impact of prescribing cascades can be substantial, leading to falls, organ injury, unnecessary imaging and tests, and more. Join us as we explore how to recognize and prevent these harmful cascades in your patients. Episode resource links: Adrien O, Mohammad AK, Hugtenburg JG, et al. Prescribing cascades with recommendations to prevent or reverse them: a systematic review. Drugs Aging. 2023;40(12):1085-1100. doi:10.1007/s40266-023-01072-yPubMedGoogle ScholarCrossref Brath H, Mehta N, Savage RD, et al. What is known about preventing, detecting, and reversing prescribing cascades: a scoping review. J Am Geriatr Soc. 2018;66(11):2079-2085. doi:10.1111/jgs.15543PubMedGoogle ScholarCrossref Daunt R, McGettigan S, Kelly L, Curtin D, O'Mahony D. Detection of Potential Prescribing Cascades in Multimorbid Older Patients Hospitalised with Acute Illness-An Observational Prospective Prevalence Study. Drugs Aging. 2025;42(6):535-546. doi:10.1007/s40266-025-01201-9 Growdon ME, Tjota N, Campbell R, et al. Decision-Making and Downstream Outcomes of the Gabapentinoid-Diuretic Prescribing Cascade. JAMA Netw Open. 2025;8(12):e2545274. doi:10.1001/jamanetworkopen.2025.45274 McCarthy LM, Savage R, Dalton K, et al. ThinkCascades: a tool for identifying clinically important prescribing cascades affecting older people. Drugs Aging. 2022;39(10):829-840. doi:10.1007/s40266-022-00964-9PubMedGoogle ScholarCrossref O'Mahony, D., Cherubini, A., Guiteras, A.R. et al. STOPP/START criteria for potentially inappropriate prescribing in older people: version 3. Eur Geriatr Med 14, 625–632 (2023). https://doi.org/10.1007/s41999-023-00777-y Rochon, P.A., O'Mahony, D., Cherubini, A. et al. International expert panel's potentially inappropriate prescribing cascades (PIPC) list. Eur Geriatr Med 16, 1573–1584 (2025). https://doi.org/10.1007/s41999-025-01215-x Young EH, Pan S, Yap AG, Reveles KR, Bhakta K. Polypharmacy prevalence in older adults seen in United States physician offices from 2009 to 2016. PLoS One. 2021;16(8):e0255642. Published 2021 Aug 3. doi:10.1371/journal.pone.0255642 Guest: Susan Feeney, DNP, FNP-BC, NP-C Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.
It's often the prior generations that pass learning lessons down to their successors, but with Gen Z leading the revival in the Christian Church, should Millennials, Gen X, and Boomers be learning from them? Join us for a conversation with ACFstudents Leader Daven Ballejo.
Everybody gets older. Admit it or not. The question is, “Will we grow sweeter, or will we rot?” Once all the children have left the nest and two people who honeymooned together twenty-five or thirty years ago are left to “start over,” how can they resist negative tendencies and stay young at heart? How can they support each other's growth toward spiritual maturity? Solomon, in the last two chapters of Ecclesiastes, set forth five reminders that couples must heed if they want to get better as they get older.Download Message Mates To support this ministry financially, visit: https://www.oneplace.com/donate/1118/29?v=20251111
Recorded on Justin's actual birthday, the guys talk about Curb Your Enthusiasm, Predator: Badlands, The Pitt, and a love they don't talk much on the show: music.
Today on the Live for More Podcast, we tackle one of the most debated passages in the New Testament: Titus 2:1–10.This episode covers biblical manhood and womanhood, what submission is and isn't, how the gospel brings dignity to the home, why the church needs every generation, and what to do with the Bible's language around bondservants/slavery in the Roman world.We also talk about identity—how the enemy tries to convince people they're “too young” or “too old” to matter—and why Scripture insists that every believer has a real place in God's mission.Key topics:- Older men: dignity, self-control, steadfast faith- Older women & younger women: discipleship across generations- What biblical submission is NOT (abuse, harm, sin)- The dignity of the home and friendship in marriage (“phileo”)- Bondservants in the Roman Empire and gospel-shaped work ethic- Doing everything “as unto the Lord” in ordinary, lowly seasonsIf this helped you, share it with someone in a different stage of life.Listen, learn, and live for more.To support this ministry and help us continue to reach people all around the world click here: https://riveroakchurch.org/give/Support the show
Something really cool is happening in classrooms at Oak Leaf Elementary School these days. Older students are stepping up and leading by example, proving to everyone that life is better with books. On this episode of the Supercast, meet some sixth-graders who are taking their love for literacy to the kindergarten classroom. They are reading to younger kids as part of the Planet Kindergarten literacy program. Audio Transcription Transcription coming soon.
Orla spoke with Neil about how she is coping with abstaining from alcohol since last July
It's been six weeks since Lisa's breast cancer diagnosis. In this episode, she and Trudy spend time talking about how the experience of living with cancer is an excellent teacher. Lisa explains how her perspective on life is being shaped and re-shaped every day. Trudy asks about the role her positive attitude plays as she moves toward surgery and treatment. It's an episode about gratitude, attitude, and platitudes. (05:40) - Bad things are good teachers (10:23) - Perspective is everything (17:57) - Things just happen (24:18) - The attitude factor (33:15) - Life is a thread (36:04) - Everyday joy Read our blog at CroneCast.caShare your questions and comments at cronecast.ca/contact. We want to hear from you about all things crone.
H. Alan Scott/Sadie Pines and Kerri Doherty revisit The Golden Girls season 6 episode "Older and Wiser," where they discuss the 1964 Tokyo Olympics, why Dorothy's plan is terrible, and why H. Alan can't eat Dairy Queen ice cream. Join the GG VIP Club at Patreon.com/GoldenGirlsPodcastWatch video versions of the podcast on YouTube.com/OutonTheLanaiFor more Golden Girls greatness, visit OutOnTheLanai.com and follow us at...instagram.com/OutOnTheLanaiOfficialfacebook.com/GoldenGirlsPodcasttwitter.com/GoldenGirlsPodFOLLOW H. ALAN SCOTT/SADIE PINES...instagram.com/SadiePinesinstagram.com/HAlanScottlinktr.ee/HAlanScottFOLLOW KERRI DOHERTY...instagram.com/squidsytwitter.com/SquidEatSquidSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Katherine Terrell, a Saints reporter for ESPN, joined Sports Talk. Terrell previewed the start of NFL free agency for New Orleans. She questioned the future of Demario Davis and Cam Jordan. Terrell also broke down the team's needs at RB, DL, and special teams.
Welcome to Catholic Apologetics, led by Dr. Jim Dobbins, Author of Take My Hand: A Personal Retreat Companion. Just finished an RCIA program? This is the next stop on your faith journey. In these classes, we look at the different truths of Catholic doctrine and why we know they are true. We also discuss apologetics, spiritual growth, examine the liturgy of the Catholic Mass, and do scripture studies. Please encourage your friends to listen. I also encourage you to leave a comment about our podcasts. If you want the slides or any other documents for any class, just e-mail me at jhdphd@gmail.com and I will reply with the documents attached. If you wish, I will also add you to the class materials distribution list so that each time I send anything out for the class you will get it. If you are getting the podcast files from iTunes and would like to see the full set of available classes for download, you can see and download them all at http://yorked.podomatic.com. Older podcasts are now stored at a free podcast site at Podcast.com. The link to the podcasts there is: http://poddirectory.com/podcast/86506/dr-james-dobbins-catholic-apologetics We ask you to also consider going to http://yorked.podomatic.com and becoming a subscriber. It is free, helps our ratings, and thus helps us reach and help more people. This session is one of our discussions from our study of the Gospel of John. Please also let me know if there is a particular topic you would like to see addressed. skvEapm1rLLW8foJsII1
Welcome to Catholic Apologetics, led by Dr. Jim Dobbins, Author of Take My Hand: A Personal Retreat Companion. Just finished an RCIA program? This is the next stop on your faith journey. In these classes, we look at the different truths of Catholic doctrine and why we know they are true. We also discuss apologetics, spiritual growth, examine the liturgy of the Catholic Mass, and do scripture studies. Please encourage your friends to listen. I also encourage you to leave a comment about our podcasts. If you want the slides or any other documents for any class, just e-mail me at jhdphd@gmail.com and I will reply with the documents attached. If you wish, I will also add you to the class materials distribution list so that each time I send anything out for the class you will get it. If you are getting the podcast files from iTunes and would like to see the full set of available classes for download, you can see and download them all at http://yorked.podomatic.com. Older podcasts are now stored at a free podcast site at Podcast.com. The link to the podcasts there is: http://poddirectory.com/podcast/86506/dr-james-dobbins-catholic-apologetics We ask you to also consider going to http://yorked.podomatic.com and becoming a subscriber. It is free, helps our ratings, and thus helps us reach and help more people. This session is one of our discussions from our study of the Gospel of John. Please also let me know if there is a particular topic you would like to see addressed. skvEapm1rLLW8foJsII1
Katherine Terrell, a Saints reporter for ESPN, joined Sports Talk. Terrell previewed the start of NFL free agency for New Orleans. She questioned the future of Demario Davis and Cam Jordan. Terrell also broke down the team's needs at RB, DL, and special teams.
replacement parts What Happens When Replacement Parts Disappear? | Episode 599 Good morning, this is James from SurvivalPunk.com. Today we're talking about something that most people don't think about until it's too late. What happens when something breaks… and you can't get the replacement part anymore? Planned obsolescence. And what you can actually do about it. Planned Obsolescence When I first learned about planned obsolescence, it pissed me off. The idea that companies intentionally design products to fail after a few years so you have to buy another one. Your phone getting slower after a couple years. Appliances dying earlier than they should. Meanwhile your grandparents had a refrigerator from the 1950s that ran forever. The difference? It wasn't designed to die. Modern products often are. The Repair Problem Even if something can be repaired, that doesn't mean you'll be able to. Repairmen aren't nearly as common as they used to be. And a lot of things aren't built to be repaired anymore. Cars are a perfect example. Older vehicles were simple. You could practically climb inside the engine bay and remove parts comfortably. Newer cars? To replace a starter in one car I worked on, I had to remove the front wheel and drop the part out through the wheel well. Ridiculous. And then you've got sensors everywhere. A tiny sensor fails and suddenly the whole car refuses to run. The Real Problem: Parts Disappear Even if you know how to fix something, there's another issue. Replacement parts eventually stop being made. Say you have a washer — the JamesCo Washer 2000. For years, replacement parts exist. OEM parts. Aftermarket parts. Repair manuals. But eventually the manufacturer stops making them. Suppliers stop stocking them. And suddenly your washer becomes unrepairable — not because the repair is impossible, but because the part doesn't exist anymore. Strategy #1: Stock Common Failure Parts If you've got the space and money, this is a powerful strategy. Find out what parts fail most often. Examples: Ignition coils Fuel pumps Sensors Belts Filters Control boards You don't need to stock every part. Just the ones most likely to fail. I once suspected my fuel pump might go bad, so I ordered a replacement ahead of time. Turned out the issue was something else… so the pump sat in my garage for months. Then one day the fuel pump actually died. And I already had the part sitting there. Problem solved. Strategy #2: Learn Workarounds Sometimes you don't need the part. You just need a workaround. Example: catalytic converters. A friend once told me two tricks: One — cut it open and clean it out. Two — if you live somewhere without emissions testing, cut it out and straight pipe it. Not always legal everywhere — but the point is there are often solutions people have discovered that extend the life of equipment. Another time I ran over a rock that punctured my transmission pan. Fluid leaked out everywhere. Instead of replacing the entire pan, I used steel epoxy putty and sealed the hole. Worked perfectly. Sometimes the “temporary fix” lasts forever. Strategy #3: Make Your Own Parts This is where things get really interesting. With modern tools, individuals can manufacture small parts. Two powerful options: 3D printers Small CNC machines These can produce: brackets clips plastic connectors housings mounts small mechanical parts And many of these designs are already shared online. Someone else might have already solved the exact problem you’re facing. Download the file. Print the part. Fix the machine. There's Also a Business Opportunity Think about this. If a product has a common failure point… And replacement parts are no longer available… Whoever figures out how to make that part can sell it. People do this already. They reproduce discontinued parts for: vehicles appliances electronics tools Sometimes a simple plastic part that costs 50 cents to print can sell for $20 because it solves a real problem. Preparedness Angle From a preparedness standpoint, this matters a lot. If supply chains break down, replacement parts will become extremely hard to find. You won't be able to just order them online. Being able to: stock parts repair equipment improvise fixes manufacture replacements …is a massive resilience advantage. Final Thoughts Everything breaks eventually. And the modern world is not designed to help you repair things. It's designed to make you replace them. But if you think ahead… Stock a few parts. Learn some workarounds. And maybe even learn to manufacture simple components. You can keep things running long after everyone else has given up. This is James from SurvivalPunk.com. DIY to survive. Amazon Item of the Day Steel Reinforced Epoxy Putty Stick Steel Epoxy Putty Repair StickPerfect for sealing cracks, holes, and emergency repairs on metal equipment. J-B Weld SteelStik, 1 Hour Cure, Steel Reinforced Epoxy Putty Stick – 2 Pack, Dark Grey (8267-2) Think this post was worth 20 cents? Consider joining The Survivalpunk Army and get access to exclusive content and discounts! Don't forget to join in on the road to 1k! Help James Survivalpunk Beat Couch Potato Mike to 1k subscribers on Youtube Want To help make sure there is a podcast Each and every week? Join us on Patreon Subscribe to the Survival Punk Survival Podcast. The most electrifying podcast on survival entertainment. Itunes Pandora RSS Spotify Like this post? Consider signing up for my email list here > Subscribe Join Our Exciting Facebook Group and get involved Survival Punk Punk's The post What Happens When Replacement Parts Disappear? | Episode 599 appeared first on Survivalpunk.
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How can anyone agree on the age of the universe? And how can we be so confident if it's all just a bunch of models? What if the universe is extra lumpy, does that change anything? I discuss these questions and more in today's Ask a Spaceman! Support the show: http://www.patreon.com/pmsutter All episodes: http://www.AskASpaceman.com Watch on YouTube: http://www.youtube.com/PaulMSutter Read a book: https://www.pmsutter.com/books Keep those questions about space, science, astronomy, astrophysics, physics, and cosmology coming to #AskASpaceman for COMPLETE KNOWLEDGE OF TIME AND SPACE! Big thanks to my top Patreon supporters this month: Justin G, Chris L, Alberto M, Duncan M, Corey D, Michael P, Naila, Sam R, Joshua, Scott M, Rob H, Scott M, Louis M, John W, Alexis, Gilbert M, Rob W, Jessica M, Jules R, Jim L, David S, Scott R, Heather, Mike S, Pete H, Steve S, Lisa R, Kevin B, Aileen G, Steven W, Deb A, Michael J, Phillip L, Steven B, Mark R, Alan B, Craig B, Richard K, Joe R, David P, Justin, Tracy F, Ella F, Thomas K, James C, Syamkumar M, Homer V, Mark D, Bruce A, Tim Z, Linda C, The Tired Jedi, Bob C, Stephen A, James R, Allen E, Michael S, Reinaldo A, Sheryl, David W, Chris, Michael S, Erlend A, James D, Karl W, Den K, Edward K, Scott K, Vivek D, Jennifer D, Barbara C, Brad, Azra K, Steve R, Koen G, Scott N, and M D Malahy! Hosted by Paul M. Sutter.
The 365 Days of Astronomy, the daily podcast of the International Year of Astronomy 2009
Hosted by Dr. Paul M. Sutter. How can anyone agree on the age of the Universe? And how can we be so confident if it's all just a bunch of models? What if the Universe is extra lumpy, does that change anything? I discuss these questions and more in today's Ask a Spaceman! Support the show: http://www.patreon.com/pmsutter All episodes: http://www.AskASpaceman.com Watch on YouTube: http://www.youtube.com/PaulMSutter Read a book: https://www.pmsutter.com/books Keep those questions about space, science, astronomy, astrophysics, physics, and cosmology coming to #AskASpaceman for COMPLETE KNOWLEDGE OF TIME AND SPACE! Big thanks to my top Patreon supporters this month: Justin G, Chris L, Alberto M, Duncan M, Corey D, Michael P, Naila, Sam R, Joshua, Scott M, Rob H, Scott M, Louis M, John W, Alexis, Gilbert M, Rob W, Jessica M, Jules R, Jim L, David S, Scott R, Heather, Mike S, Pete H, Steve S, Lisa R, Kevin B, Aileen G, Steven W, Deb A, Michael J, Phillip L, Steven B, Mark R, Alan B, Craig B, Richard K, Joe R, David P, Justin, Tracy F, Ella F, Thomas K, James C, Syamkumar M, Homer V, Mark D, Bruce A, Tim Z, Linda C, The Tired Jedi, Bob C, Stephen A, James R, Allen E, Michael S, Reinaldo A, Sheryl, David W, Chris, Michael S, Erlend A, James D, Karl W, Den K, Edward K, Scott K, Vivek D, Jennifer D, Barbara C, Brad, Azra K, Steve R, Koen G, Scott N, and M D Malahy! We've added a new way to donate to 365 Days of Astronomy to support editing, hosting, and production costs. Just visit: https://www.patreon.com/365DaysOfAstronomy and donate as much as you can! Share the podcast with your friends and send the Patreon link to them too! Every bit helps! Thank you! ------------------------------------ Do go visit http://www.redbubble.com/people/CosmoQuestX/shop for cool Astronomy Cast and CosmoQuest t-shirts, coffee mugs and other awesomeness! http://cosmoquest.org/Donate This show is made possible through your donations. Thank you! (Haven't donated? It's not too late! Just click!) ------------------------------------ The 365 Days of Astronomy Podcast is produced by the Planetary Science Institute. http://www.psi.edu Visit us on the web at 365DaysOfAstronomy.org or email us at info@365DaysOfAstronomy.org.
Host: Darryl S. Chutka, M.D. Guests: Jae K. Oh, M.D., Tahir S. Kafil, M.D. Diastolic heart failure is also known as heart failure with preserved ejection fraction. Although we don't hear the term all that often, it actually represents a fairly large percentage of all cases of heart failure. Some studies suggest it represents the majority of heart failure cases. Older adults are most commonly affected with symptoms similar to those of systolic heart failure. So how do we suspect diastolic heart failure? How should the diagnosis be established, and how does the treatment differ from systolic heart failure? Finally, what role do primary care providers play in the management of the condition? These are some of the questions I'll be asking my guests, Dr. Jae Oh and Dr. Tahir Kafil, both cardiologists in the Department of Cardiovascular Disease at the Mayo Clinic as we discuss “Diastolic Heart Failure”. Mayo Clinic Talks: Heart Health | Mayo Clinic School of Continuous Professional Development Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development
Mr. Beast Biography Flash a weekly Biography.Hey there, fabulous listeners, its your girl Roxie Rush here, your AI-powered gossip whirlwind, and thank you for tuning into the MrBeast podcast. Being AI means I sift through the chaos faster than you can say viral video, delivering the hottest, verified scoops without the fake news fluffwhats not to love?Buckle up, because MrBeast, aka Jimmy Donaldson, is making power moves that scream empire builder. Just days ago, Beast Industries snapped up Step, the Gen Z banking app with over 7 million users peddling credit-building and investing tools for teens, according to TechCrunch and The Publish Press. Jimmy spilled on X, Nobody taught me about investing or managing money growing upI want to give millions of young people the financial foundation I never had. TechCrunch reports hes eyeing a financial education YouTube channel and even Beast Financial trademarks, with whispers of an IPO push via recurring revenue plays. This could redefine his $5 billion Beast empire long-term, darlingtalk about leveling up from chocolates to cash flow.But hold the confettiKalshi dropped a bombshell Wednesday, fining and suspending MrBeasts editor Artem Kaptur $15,000 for insider trading on prediction markets betting his videos success, per CBS News. Beast Industries fired back with zero tolerance and an independent probe underway. No direct Jimmy drama, but it spotlights the heat on his fast-growing team.Older chatter from Fortune echoes Jimmy borrowing cash from mom for his wedding despite a $2.6 billion net worth, all reinvested into contenthes laser-focused, not lounging.No fresh public sightings or social fireworks in the last 24 hours, but this Step acquisition? Pure biographical gold, positioning Beast as fintech king.Thats your MrBeast flash, crewthank you for listening, hit subscribe to never miss an update on MrBeast, and search Biography Flash for more great biographies. Muah!And that is it for today. Make sure you hit the subscribe button and never miss an update on Mr. Beast. Thanks for listening. This has been a Quiet Please production."Get the best deals https://amzn.to/4mMClBvThis content was created in partnership and with the help of Artificial Intelligence AI
In this episode of the Revolutionize Your Retirement Interview with Experts series, host Dori Mintzer speaks with Dr. Linda P. Fried, a global leader in healthy aging, about why rising longevity is a hard-won success rather than a crisis, how the shift to older populations is transforming societies worldwide, what older adults most want from later life (independence, purpose, learning, contribution, and mattering), and the many often-unseen ways older people already bolster economies and communities through work, caregiving, and volunteering, challenging fear-based narratives like the “old-age dependency ratio” and the impact of ageism and age segregation.Key topics discussedThe value of longer lives and demographic change: Public health advances have added decades to average life expectancy, bringing the U.S. to the brink of having 20% of its population over 65 and creating a new demographic reality shared by many countries.What older adults want: Global and U.S. studies show older people consistently prioritize aging in place, avoiding being a burden, maintaining relationships, having purpose, lifelong learning opportunities, respected voices in community life, and roles where they truly matter.Mattering, retirement, and mental health: Research highlighted in the Wall Street Journal finds many retirees feel less valued, needed, and connected, with loss of mattering predicting post‑retirement depression and illustrating how identity and health are tied to meaningful roles.Economic and civic contributions of older adults: Older people's paid work and volunteering together are estimated to equal roughly 7% of U.S. GDP, while economic evidence shows older workers strengthen rather than crowd out opportunities for younger workers.Ageism, age segregation, and distorted narratives: Dominant policy tools such as the old‑age dependency ratio frame older adults as dependents, reinforcing ageist beliefs and obscuring real contributions, especially in a highly age‑segregated society where generations rarely mix.Capabilities and assets of later life: Science increasingly documents that aging can bring new cognitive strengths (complex problem analysis, values‑based judgment, breaking problems into steps), greater prosocial motivation, generosity, emotional balance, capacity for conflict mediation, and a generative drive to leave the world better.Connect with Dr. Linda P. FriedLinkedIn: Linda P. FriedLearn more: Columbia UniversityWhat to do next: Click to grab our free guide, 10 Key Issues to Consider as You Explore Your Retirement Transition Please leave a review at Apple Podcasts. Join our Revolutionize Your Retirement group on Facebook.
Contributor: Taylor Lynch MD Educational Pearls: Melatonin is an endogenous hormone released primarily by the pineal gland Also released by extrapineal regions in the retina, the GI tract, and some immune cells Peak secretion occurs at night and is suppressed during the day Secretion and production decrease with age Older patients experience the greatest improvement in sleep latency and sleep quality Mechanism of action in the suprachiasmatic nucleus of the hypothalamus MT1 receptor Reduces normal firing MT2 receptor Shifts the circadian rhythm FDA approved for insomnia Decreases sleep latency by 7 minutes Increases total sleep time by 8 minutes FDA approved for circadian sleep-wake disorders Jet lag Most effective in west-to-east travel Best if crossing at least 5 time zones Shift work A study examined ED physicians and nurses with rotating shifts Modest increase in deep sleep percentage No difference in cognition or reaction time the day after taking melatonin Nurses on rotating night shifts experienced increased total sleep time by 20 minutes Dosing 0.5 - 3 mg is the most evidence-based dosing Higher doses increase the risk of rebound grogginess but do not improve outcomes References Ahmad SB, Ali A, Bilal M, et al. Melatonin and Health: Insights of Melatonin Action, Biological Functions, and Associated Disorders. Cell Mol Neurobiol. 2023;43(6):2437-2458. doi:10.1007/s10571-023-01324-w Herxheimer A, Petrie KJ. Melatonin for the prevention and treatment of jet lag. Cochrane Database Syst Rev. 2002;(2):CD001520. doi:10.1002/14651858.CD001520 Morgenthaler TI, Lee-Chiong T, Alessi C, Friedman L, Aurora RN, Boehlecke B, Brown T, Chesson AL Jr, Kapur V, Maganti R, Owens J, Pancer J, Swick TJ, Zak R; Standards of Practice Committee of the American Academy of Sleep Medicine. Practice parameters for the clinical evaluation and treatment of circadian rhythm sleep disorders. An American Academy of Sleep Medicine report. Sleep. 2007 Nov;30(11):1445-59. doi: 10.1093/sleep/30.11.1445. Erratum in: Sleep. 2008 Jul 1;31(7):table of contents. PMID: 18041479; PMCID: PMC2082098. Thottakam BMVJ, Webster NR, Allen L, Columb MO, Galley HF. Melatonin Is a Feasible, Safe, and Acceptable Intervention in Doctors and Nurses Working Nightshifts: The MIDNIGHT Trial. Front Psychiatry. 2020;11:872. Published 2020 Aug 27. doi:10.3389/fpsyt.2020.00872 Summarized and edited by Jorge Chalit, OMS4 Donate: https://emergencymedicalminute.org/donate/ Join our mailing list: http://eepurl.com/c9ouHf
Topics covered in this episode: Raw+DC: The ORM pattern of 2026? pytest-check releases Dataclass Wizard SQLiteo - “native macOS SQLite browser built for normal people” Extras Joke Watch on YouTube About the show Sponsored by us! Support our work through: Our courses at Talk Python Training The Complete pytest Course Patreon Supporters Connect with the hosts Michael: @mkennedy@fosstodon.org / @mkennedy.codes (bsky) Brian: @brianokken@fosstodon.org / @brianokken.bsky.social Show: @pythonbytes@fosstodon.org / @pythonbytes.fm (bsky) Join us on YouTube at pythonbytes.fm/live to be part of the audience. Usually Monday at 11am PT. Older video versions available there too. Finally, if you want an artisanal, hand-crafted digest of every week of the show notes in email form? Add your name and email to our friends of the show list, we'll never share it. Michael #1: Raw+DC: The ORM pattern of 2026? ORMs/ODMs provide great support and abstractions for developers They are not the native language of agentic AI Raw queries are trained 100x+ more than standard ORMs Using raw queries at the data access optimizes for AI coding Returning some sort of object mapped to the data optimizes for type safety and devs Brian #2: pytest-check releases 3 merged pull requests 8 closed issues at one point got to 0 PR's and 1 enhancement request Now back to 2 issues and 1 PR, but activity means it's still alive and being used. so cool Check out changelog for all mods A lot of changes around supporting mypy I've decided to NOT have the examples be fully --strict as I find it reduces readability See tox.ini for explanation But src is --strict clean now, so user tests can be --strict clean. Michael #3: Dataclass Wizard Simple, elegant wizarding tools for Python's dataclasses. Features
Brad shares results from a large national research project examining somatic cell count (SCC) and mastitis risk in U.S. organic dairy herds, using more than 2 million DHI test-day records from 430 farms across 31 states. The discussion highlights how SCC is influenced by multiple factors, including cow age, stage of lactation, milk production, breed, season, region, and herd size. Older cows, early-lactation animals, and lower-producing cows were most likely to have elevated SCC, while heat stress—especially during summer months—and larger herd size significantly increased risk. Because organic systems cannot rely on antibiotics, Brad emphasizes prevention strategies such as improved fresh-cow management, heat abatement, careful monitoring of chronic cows, and strong milking hygiene as key tools for controlling mastitis and maintaining milk quality. Questions, comments, scathing rebuttals? -> themoosroom@umn.edu or call 612-624-3610 and leave us a message!Linkedin -> The Moos RoomTwitter -> @UMNmoosroom and @UMNFarmSafetyFacebook -> @UMNDairyYouTube -> UMN Beef and Dairy and UMN Farm Safety and HealthInstagram -> @UMNWCROCDairyExtension WebsiteAgriAmerica Podcast Directory
When you're a billionaire CEO, philanthropist, entrepreneur in your 80s, you definitely have valuable life advice to share. We're all ears! Bianca Gonzalez sits down with a Filipina-American trailblazer Loida Nicolas Lewis in this special episode of Paano Ba ‘To.Loida's book, Look Younger When You're Older is available in bookstores nationwide and in leading e-commerce platforms!#LookYoungerWhenYoureOlder#LoidaNicolasLewisFollow #PaanoBaTo on our socials!IG: www.instagram.com/paanobatoFB Group: www.facebook.com/groups/paanobatoTiktok: www.tiktok.com/@askpaanobato To know more about the work of Bianca Gonzalez, check out her pages on IG/FB/X/YouTube/Tiktok: @iamsuperbianca Paano Ba ‘To?!Created by Bianca GonzalezEst. 2014
CardioNerds (Dr. Jenna Skowronski [Heart Failure Council Chair], Dr. Shazli Khan, and Dr. Josh Longinow) are joined by renowned leaders in the field of AHFTC (Advanced Heart Failure and Transplant Cardiology) and mechanical circulatory support, Dr. Jeff Teuteberg and Dr. Mani Daneshmand to continue the discussion of advanced heart failure therapies by taking a deep dive into the world of durable LVADs (Left Ventricular Assist Devices). In this episode, we will review the history of ventricular assist devices, the basics of LVAD function, selection criteria for LVAD therapy, and surgical nuances of LVAD implantation. Audio Editing by CardioNerds intern, Joshua Khorsandi. Enjoy this Circulation 2022 Paths to Discovery article to learn about the CardioNerds story, mission, and values. CardioNerds Heart Success Series PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls There have been significant advances in the field of MCS/LVAD therapy since the first implanted LVAD in the 1960s, to the first FDA approved device in the early 2000's, to now the HM3 LVAD, with the most important change being a centrifugal flow/magnetically levitated design that led to minimized hemocompatibility-related adverse events (HRAE's) (MOMENTUM 3 trial comparing HM2 and HM3). The REMATCH trial in 2001 was a pivotal trial for LVAD therapy, demonstrating that in a population of patients with advanced HF (70% IV inotrope dependent), LVAD therapy significantly improved survival at both 1 and 2 years as compared to medical therapy alone. MOMENTUM 3 trial was a landmark trial for the HM3 device, showing that in a population of end stage HF patients (86% inotrope dependent, 32% INTERMACS 1-2, and 60% DT strategy), 5-year survival with HM3 was 58% and HM3 had lower HRAE's compared with HM2. There are both patient-specific factors and surgical considerations when it comes to candidacy for LVAD therapy. RV function prior to LVAD is a key determinant for success post-LVAD Many patients being considered for LVAD may not have robust RV function, however, predicting RV failure after LVAD is exceedingly difficult. In general, it doesn’t matter how bad the RV may look on imaging; we care more about the pre-LVAD hemodynamics (look at the PAPi and RA/wedge ratio). What happens in the OR may be the most important determinant of how the RV will do with the LVAD! Notes Notes drafted by Dr. Josh Longinow. 1. Historical background of heart pumps and LVADs LVAD Evolution FDA approval year 2001 2008 2012 2017 Pump HeartMate XVE HeartMate II Heartware HVAD HeartMate III Flow/Design Features Pulsatile Technology Continuous flow Axial design Continuous flow Centrifugal design Continuous flow Full MagLev + Centrifugal design The 1960's ushered in the first ‘LVADs', when the first air-powered ‘LVAD' was implanted. It kept the patient alive for four days before the patient expired. The first generation of LVADs were pulsatile pumps The first nationally recognized, FDA approved LVAD was the HeartMate XVE (late 1990s to early 2000s, REMATCH trial). The XVE pump used compressed air (pneumatically driven) to power the pump. Prior to the XVE, OHT was the standard of care for patients with advanced, end-stage heart failure. The second and third generations of LVADs were non-pulsatile, continuous flow devices and included the HVAD, HM2, and HM3 devices. MOMENTUM 3 was a landmark trial for the HM3 device, showing that in a population of sick patients with end stage HF (86% inotrope dependent, 32% INTERMACS 1-2, and 60% DT strategy), 5-year survival with HM3 was 58% and HM3 had lower HRAE's compared with HM2. The only pump that is currently FDA approved for implant is the HM3, although other pumps are in clinical trials (BrioVAD system, INNOVATE Trial). 2. What are LVADs, and how do they work? In simplest terms, the LVAD is a heart pump comprised of several key mechanistic components: Inflow cannula Mechanical pump Outflow cannula Driveline Controller/Power source The HM3 differs from its predecessors (HM2 and HVAD) in several key ways; HM3 is placed intrapericardial whereas the HM2 was placed pre-peritoneal. Perhaps most importantly, the HM3 is a fully magnetically levitated, centrifugal flow pump, whereas the HM2 is an axial flow device. Axial flow pumps are not magnetically levitated, leading to more friction produced between the ruby bearing's contact with the pump rotors, and higher rates of hemocompatibility related adverse events (HRAEs, i.e. pump thrombosis) and the HM2 was ultimately discontinued in favor of the HM3 (MOMENTUM 3 trial). 3. What do the terms ‘Destination Therapy' (DT) or ‘Bridge to Transplant' (BTT) mean when it comes to LVADs? When LVADs first came on the stage, EVERYONE was a BTT; these early pumps weren't designed for long term use (I.e. REMATCH Trial, Heartmate XVE) Destination therapy means the LVAD was placed in leu of transplant because there are contraindications to transplant REMATCH trial brought about the concept of “Destination therapy”, comparing outcomes in patients (with contraindications for transplant) who received an LVAD vs optimal medical therapy Bridge to transplant means we are placing the LVAD in a patient who may not be a transplant candidate at this moment in time (is too sick, or conversely, not sick enough), but may be down the line Bridge to recovery is another term used when the LVAD is being placed for a patient we think may have a recoverable cardiomyopathy 4. What are some factors we should consider when assessing a patient’s candidacy for LVAD, in general, and from a surgical perspective? Patient factors Older age might push us towards thinking LVAD rather than transplant In general, age > 70 is the cutoff for transplant, but this is not a hard cut off and varies institution to institution In general, think about things that help predict recovery after a major surgery; Frailty and Nutritional status are important, we try to optimize these prior to LVAD implant Right ventricular function remains the Achilles heel of LV support We know that needing temporary RV support post LVAD puts you on a different survival curve than patients who don’t need RVAD support Studies have not been able to successfully predict who will develop RV failure after LVAD implantation What happens in the time between when the patient goes to the OR and when they get back to the ICU is an important determinant who might develop RV failure post LVAD Surgical techniques such as implanting the HM3 in the intra-thoracic cavity, rather than intra-pericardial may help maintain LV/RV geometry to help optimize the RV post LVAD Surgical considerations for LVAD candidacy Small, hypertrophied LV: HM3 inflow cannula is small, but small hypertrophied ventricles tend towards chamber collapse during systole causing suction, needing to run slower with lower flow rates Chest size/diameter: pumps have gotten so small now, that for adults, these have become less of a consideration BMI: low BMI used to be more of a concern with the older pumps due to where they were placed, and the relative size of the pump itself, not so much now with the smaller HM 3 pumps Calcified LV apex: would increase risk of stroke, bleeding Driveline tunneling becomes a concern in the super obese population, higher risk for driveline infections (might tunnel these driveline's shorter, and to a less fatty region of the abdomen, could even tunnel out the thoracic cavity in the super obese to limit skin motion) 5. Is there a role for MCS (i.e. temporary LVAD such as Impella) in pre-habilitation of patients prior to LVAD surgery? The theory of being able to improve systemic perfusion, decongest the organs, and make the patient feel better prior to surgery makes sense, but becomes problematic due to the lack of a hard end point/time for prehabilitation which might risk delays in surgery More likely that it can lead to delay in the surgery, with less-than-optimal benefit; you don't want to prolong the wait for surgery and increase the risk for complications prior to surgery An Impella 5.5 is currently FDA approved for 2 weeks of support, not 2 months so timing is important to keep in mind It’s unlikely that you will take a patient and convert them from a malnourished, cachectic person in 2 weeks’ time 6. Is there a role for LVAD therapy in the younger patient population? Should we be thinking of LVAD up front for these patients, with the goal of transplanting down the line? Recovery may be more likely in certain populations, particularly younger females with smaller LV's; in those populations, perhaps bridge to recovery should be the focus, optimizing them on GDMT etc. The replacement of transplant, with MCS (LVAD) in young patients has become a topic of discussion, because these pumps have become better and better, with the thinking that an LVAD could bridge a patient for 10 years or so, and they could get a transplant later It is still a big unknown, but several concerns exist Patients who get LVADs might end up with complications that become contraindication to transplant down the line (stroke, sensitization etc) Patients and providers are more hesitant because of the more recent iteration for the UNOS criteria for OHT listing which no longer gives patients with an uncomplicated LVAD higher priority, and therefore they could end up waiting a longer time for a heart after undergoing LVAD References Rose EA, Gelijns AC, Moskowitz AJ, et al. Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med. 2001;345(20):1435-1443. doi:10.1056/NEJMoa012175 Mehra MR, Uriel N, Naka Y, et al. A Fully Magnetically Levitated Left Ventricular Assist Device – Final Report. N Engl J Med. 2019;380(17):1618-1627. doi:10.1056/NEJMoa1900486 Mancini D, Colombo PC. Left Ventricular Assist Devices: A Rapidly Evolving Alternative to Transplant. J Am Coll Cardiol. 2015;65(23):2542-2555. doi:10.1016/j.jacc.2015.04.039 Mehra MR, Goldstein DJ, Cleveland JC, et al. Five-Year Outcomes in Patients With Fully Magnetically Levitated vs Axial-Flow Left Ventricular Assist Devices in the MOMENTUM 3 Randomized Trial. JAMA. 2022;328(12):1233-1242. doi:10.1001/jama.2022.16197 Rose EA, Moskowitz AJ, Packer M, et al. The REMATCH trial: rationale, design, and end points. Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure. Ann Thorac Surg. 1999;67(3):723-730. doi:10.1016/s0003-4975(99)00042-9 Kittleson MM, Shah P, Lala A, et al. INTERMACS profiles and outcomes of ambulatory advanced heart failure patients: A report from the REVIVAL Registry. J Heart Lung Transplant. 2020;39(1):16-26. doi:10.1016/j.healun.2019.08.017 Mehra MR, Netuka I, Uriel N, et al. Aspirin and Hemocompatibility Events With a Left Ventricular Assist Device in Advanced Heart Failure: The ARIES-HM3 Randomized Clinical Trial. JAMA. 2023;330(22):2171-2181. doi:10.1001/jama.2023.23204 Mehra MR, Nayak A, Morris AA, et al. Prediction of Survival After Implantation of a Fully Magnetically Levitated Left Ventricular Assist Device. JACC Heart Fail. 2022;10(12):948-959. doi:10.1016/j.jchf.2022.08.002 Bhardwaj A, Salas de Armas IA, Bergeron A, et al. Prehabilitation Maximizing Functional Mobility in Patients With Cardiogenic Shock Supported on Axillary Impella. ASAIO J. 2024;70(8):661-666. doi:10.1097/MAT.0000000000002170
What are the ancient Egyptian Coffin Texts from 4,000 years ago? How do they interweave with the Graeco-Egyptian Magical Papyri (or PGM) spells? How can we become vessels through which the conjuratory power of the Gods flows to prevail against the darkness? Jack Grayle - author, ceremonial magician, playwright, practitioner, and devotee of Hekate - shares about the Coffin Texts and how he employs them in his latest PGM course, answers listener questions and more!⇓ ⇓ ⇓►⚡Register for Jack's PGM course - https://jackgrayle.com/courses/pgm-praxis-3-the-darkness/ ►✅Jack's NEW Hekateon update (Trade Hardcover) - https://www.miskatonicbooks.com/product/the-hekataeon-by-jack-grayle-trade-hardcover/ —---------✦
Mable and Biff have enjoyed a beautiful relationship during their seven years of marriage. They have two children, ages five and two. However, Mable is facing a challenging situation with her mother, who has been pressuring her to spend more time with her during the week. Mable's father is passive, and her mother has always been the dominant figure in the home. Read, Watch, Listen: https://lifeovercoffee.com/how-do-i-honor-my-older-parents/ Will you help us to continue providing free content for everyone? You can become a supporting member here https://lifeovercoffee.com/join/, or you can make a one-time or recurring donation here https://lifeovercoffee.com/donate/.
What if singleness and marriage were never meant to be opposing seasons — but invitations to the same deeper goal?In this honest and hope-filled conversation, Lisa Harper shares her personal story of not choosing singleness — and discovering that Jesus meets us fully in the life we didn't plan. Together, we explore the tension between longing for marriage and learning contentment, and unpack what Paul the Apostle truly meant when he wrote that singleness is a gift.Lisa opens up about grief, growth, unmet expectations, and the steady faithfulness of Christ. We look at the full context of 1 Corinthians 7, gently challenge cultural narratives, and reframe what it means to walk closely with Jesus in every season.Pray while you wait with Future Husband, Present Prayers and trust God with your love story with the Dear Future Husband Prayer Journal. Pre-order both at www.christianbevere.com
In this episode, Christina Prevett discusses the importance of nutrition and fueling in geriatric patients, particularly focusing on a case study of a 69-year-old active woman. The conversation highlights the impact of low energy availability on older adults and emphasizes the need for comprehensive wellness screenings to address nutrition, recovery, and overall health promotion. Chapters 00:00 Introduction to Geriatric Nutrition and Fueling 05:12 Case Study: Understanding Low Energy Availability 10:45 The Importance of Comprehensive Wellness Screening
This week I'm joined by Nathan Killen, and we get into the stuff that doesn't show up in highlight reels — weather that doesn't cooperate, thermals that don't do what you expect, and seasons that force you to adjust whether you want to or not. We talk traditional archery, food sources, scrapes, rattling, and the little woodsmanship details that still matter no matter how much technology creeps into the picture. Nathan and I both share seasons where patience mattered more than aggression, and where trusting your gut made more difference than any piece of gear ever could. There's a thread running through this one about balance — using tools without losing the mystery, learning without overcomplicating it, and remembering that comparison will rob the joy out of this faster than a blown wind ever will. This episode is about instinct, adaptability, and keeping the hunt honest. WHAT TO EXPECT FROM PODCAST 481 Weather, thermals, and food sources dictate deer movement more than anything else. Traditional archery sharpens awareness and forces you to earn every opportunity. Older bucks live by patterns — your strategy has to adjust to theirs. Hunt the edges of sign, not just the sign itself. Woodsmanship is built through reps, not talent. Trusting your gut often beats overthinking the setup. Technology can help — but the mystery is what keeps hunting meaningful. SHOW NOTES AND LINKS: —Truth From The Stand Merch —Check out Tactacam Reveal cell cameras — Save 15% on Hawke Optics code TFTS15 —Save 20% on ASIO GEAR code TRUTH20 —Check out Spartan Forge to map your hunt —Save on Lathrop And Sons non-typical insoles code TRUTH10 —Check out Faceoff E-Bikes —Waypoint TV Learn more about your ad choices. Visit megaphone.fm/adchoices
When you are in the thick of raising children, it can feel overwhelming to sort through expectations, opinions, and the daily logistics of family life. In this conversation, Jennifer shares what nearly three decades of motherhood have taught her about choosing peace in each season, homeschooling at your own pace, navigating special needs with a focus on progress, and letting go of unnecessary pressure. This episode offers perspective and encouragement for building a peaceful family culture that reflects your unique family. In this episode, we cover: - Introducing Jennifer's family of seven children ranging from 28 to 12 years old, life on a Wisconsin cranberry farm, and decades of homeschooling - What no one tells you about having a wide age range of children and the surprising gift of older kids becoming your “allies” in family life - How perspective shifts as children grow up, get married, and start families of their own, and why the years truly do move faster than you think - Letting go of early motherhood pressures about tidy homes, perfect routines, and outside expectations in order to create a peaceful family culture - Rethinking homeschool success through the lens of progress over grade levels, especially when navigating special needs - Practical rhythms for homeschooling multiple children with different abilities without doing everything at the same time - The freedom that comes with age and experience—why comparison loses its grip and confidence grows over time - Overthinking in modern motherhood, the pressure to “get it right” the first time, and permission to change your mind as you grow - What it's actually like to become a young grandmother while still raising children at home and how that dynamic reshapes family life - Embracing the evolving nature of family seasons instead of trying to control or predict them View full show notes on the blog + watch this episode on YouTube. Thank you for supporting the sponsors that make this show possible! RESOURCES MENTIONED Master the rhythm of sourdough with confidence in my Simple Sourdough course Gain the sewing knowledge and skills every homemaker needs in my Simple Sewing series Keep all my favorite sourdough recipes at your fingertips in my Daily Sourdough cookbook CONNECT Jennifer of A Country Life | Website | YouTube | Instagram | Facebook Lisa Bass of Farmhouse on Boone | Blog | YouTube | Instagram | TikTok | Facebook | Pinterest
Severe gum disease reflects chronic inflammation and strongly links to broader health risks, including heart disease and diabetes, not just tooth loss Older adults with low dietary lycopene intake face a much higher risk of advanced gum disease compared to those who consume adequate amounts Cooked tomatoes paired with healthy fats improve lycopene absorption and support gum tissue resilience Smoking, frequent sugar intake, and ultraprocessed foods accelerate gum damage by feeding harmful bacteria and impairing blood flow to oral tissue Consistent whole-food nutrition, gentle daily oral care and mineral support strengthen gums from the inside out and lower long-term disease risk
Head Noise: I'm Losing My Best Friend & My Partner Is 17 Years Older Than Me In this Head Noise episode, we talk about two situations that can quietly reshape your relationships — friendship change and family judgement. First, how do you deal with the fear of losing your best friend when they enter a new relationship? We explore: Why the friendship changing doesn't mean the love is gone How trying to control or hold on too tightly can push someone away The difference between close and codependent friendships Why fear can damage something that doesn't need fixing How to genuinely be happy for your friend when their life evolves Then, what happens when your partner is 17 years older and your family isn't on board? i go into: Learning to live with family disappointment Why their concern often comes from protection, not rejection The importance of keeping them in the loop Why telling them sooner rather than later makes things easier This episode is about allowing relationships to evolve without trying to force certainty, and learning to stay grounded even when others don't fully understand your choices. As always, Head Noise is about responding thoughtfully instead of reacting from fear. Learn more about your ad choices. Visit megaphone.fm/adchoices
Erin and Alyssa dive into the Wall Street Journal's brutal read of Kristi Noem, social media addiction going on trial, and how the SAVE Act might forever change our elections. Then, in Sani/Petty, they discuss Elon's turn toward Jesus, the new season of Love Is Blind, and Taylor Swift's special video for the Team USA Women's Figure Skaters. A Pilot Fired Over Kristi Noem's Missing Blanket and the Constant Chaos Inside DHS (Wall Street Journal 2/12)Tough questions — and grieving families — await Mark Zuckerberg at social media addiction trial Wednesday (CNN 2/17)Trump's election bill tops 50 Senate votes, but Democrats could still block it (NBC News 2/17)House passes elections overhaul bill that could make it harder for married women to vote (The 19th News 2/11)Older women are spooked by the economy. Their vote is up for grabs (USA Today 2/16)