Podcasts about bone disease

Worried about the effects of menopause and aging on your bone health, overall strength and well-being? Then this episode of Sick Health is just what the doctor ordered! Dr. Kevin Ban sits down with Dr. Kristy DeSapri to share the science of bone health, osteoporosis, and the crucial steps to take post-menopause (and what you can do well before symptoms ever arise).Dr. Kristy DeSapri explains the physiological changes that occur in our bones as we age, highlights key risk factors, and outlines the most effective treatments available. From dietary tips to exercise routines and the benefits of hormone replacement therapy, we cover it all. Plus, learn the importance of balance training and creative ways to incorporate it into your daily routine.You don't have to compromise your lifestyle just because you're aging. With the right information on your side, you can ensure that your best years are straight ahead. In the next sixty minutes, we'll give you:1. Expert Insights into women's health and bone health.2. Practical Tips and actionable steps to improve your bone health, including diet, exercise, and lifestyle changes.3. Myth-Busting that will set the record straight about bone health and menopause.4. Holistic Approach to wellness that combines medication, lifestyle changes, and preventive measures.RESOURCES MENTIONED IN THIS EPISODE:Calcium Calculator for Various Foods:https://www.osteoporosis.foundation/educational-hub/topic/calcium-calculator https://www.bonehealthandosteoporosis.org/patients/treatment/calciumvitamin-d/steps-to-estimate-your-calcium-intake/ SHARING BEAUTY:Kenny Chesney: Get Alonghttps://www.youtube.com/watch?v=-LI8X-GhFA8 Dr. Kristi Tough DeSapri truly believes that women deserve to function at optimal health and are gatekeepers to their families' and communities' health. She is a board certified internist specializing in midlife women's health and is regarded as a national leader in the field of osteoporosis and menopause management. After fellowship training at the Cleveland Clinic, she has worked in private practice and academic medicine holding joint appointments in the Department of Ob/GYN and Internal Medicine, including being director of the Northwestern Women's Bone Health program at the Center for Sexual Medicine and Menopause at Northwestern Medicine in Chicago. She is the founding physician and owner of Bone and Body Women's Health, a specialized midlife women's health practice in the suburbs of Chicago focused on consultation and management of perimenopause, menopause, osteoporosis, and bone health. Dr. DeSapri is an invited lecturer at national academic conferences and sits on severalmedical society committees including the Association of Bone Mineral Research(ASBMR), Bone Health and Osteoporosis Foundation ( BHOF), the Menopause Society and Ms. Medicine. Since 2010 she has been an active Menopause Certified Practioner (formerly known as NAMS) which is the premier organization certifying menopause and midlife women's health providers. Dr. DeSapri is an ISCD ( International Society of Clinical Densitometry) certified clinical densitometrist and maintains her specialized ongoing certification in bone densitometry.She started her practice Bone and Body Women's Health with the goal of matchingwhat midlife women want from their medical visit with her desire to spend quality timeand expertise with her patients.Find Dr. Kristi at: https://boneandbodywh.com

The 17th International Workshop on Multiple Myeloma (iwMyeloma 2024) was held recently in Miami, FL, and brought together experts from... The post iwMyeloma 2024 Session I: approaching bone disease, clinical trial updates & the value of MRD as an endpoint in trials appeared first on VJHemOnc.

In this episode, Robert S. Brown, Jr., MD, MPH; Nancy Reau, MD; and Eric, a person living with chronic hepatitis B, discuss solutions for overcoming barriers to HBV care in older adults, including:Awareness of HBV and CHB in older adultsUpdated HBV screening and vaccination recommendationsMonitoring of renal and bone diseaseAdjustment of monitoring and treatment as a person with HBV agesPresenters: Robert S. Brown, Jr., MD, MPHVincent Astor Distinguished Professor of MedicineChief, Division of Gastroenterology and HepatologyWeill Cornell MedicineNew York, New YorkNancy Reau, MDProfessor of MedicineChief, Section of HepatologyAssociate Director, Solid Organ TransplantationRichard B. Capps Chair of HepatologyRush University Medical CenterChicago, IllinoisEric, person living with chronic hepatitis BLink to downloadable slides: please link to VM404 downloadable slides when readyLink to program: bit.ly/3L3Kz6l

In this episode of What's Your Limp? Jordan chats with filmmaker Ashley Eakin - director of the short Netflix film, FORGIVE US OUR TRESPASSES.  She has also directed episodes of Apple TV's BEST FOOT FORWARD and the Brie Larson produced Disney+ series GROWING UP.Ashley opens up about her  rare bone disease called Olliers and Maffucci Syndrome. Her disability led to body image issues and other insecurities. Ashley and Jordan discuss living with visible disabilities, how they coped with their insecurities and what they're doing with their platforms to help others in similar situations.Be sure to follow Ashley at @AshEakin on Instagram and you can visit her website at https://www.ashleyeakin.com/ to keep up with her career and future projects. And follow us at @WhatsYourLimp and @TheJordanRoss.

Happy New Year from the Sarcoma Insight Family! Episode recorded: 11/13/2022 Metastatic bone disease are a big cause of pain, morbidity and mortality for patients. The tumor is able to hijack normal bone metabolism and weaken the bone. In this episode we discuss the mechanisms of metastatic disease, diagnosis, management and treatment with Dr. Cory Couch of the Mayo clinic Links Rougraff BT, Kneisl JS, Simon MA. Skeletal metastases of unknown origin. A prospective study of a diagnostic strategy. J Bone Joint Surg Am. 1993 Sep;75(9):1276-81. Find out More about our Doctors: Dr. Izuchukwu Ibe: www.linkedin.com/in/izuchukwu-ibe-a073537a/ Dr. Elyse Brinkmann: www.linkedin.com/in/elyse-brinkmann/

In 1964, Nancy, a 5-year-old, is having her evening bath when her parents discover she has a lump on the skull the size of a grapefruit. This would mark the onset of a mysterious and debilitating disease that researchers are still struggling to understand. Over the next 40 days, medical professionals struggled to discover what was causing the lump on the skull. Each test seemed to exacerbate the swelling in Nancy's neck. In hindsight, that was a big clue, but it took doctors a while to recognize it. Instead, what happened next was a common mistake when it comes to patients with this disease. Nancy was diagnosed with terminal cancer. Doctors said she had less than a year. Yet, over the next few months, Nancy's condition didn't progress. She actually seemed to get better. Over the next few months, she was taken to a series of specialists. It was finally an oncologist who noticed something that was pivotal to her diagnosis ... her toes. Misshapen big toes — generally short and bending inward — are a hallmark of Nancy's disease. While Nancy had several telltale signs of the disease, diagnosing rare diseases is difficult in part because they're exactly that: rare. “I can see how a practicing physician may feel a rare disease, ‘I'm never going to see it.' But [this disease] is so striking that I think once you see someone with the disease … the image stays in your mind and even if someone, as a general internist or a pediatrician, never expects to see the case, you never know,” shares Dr. Eileen Shore, a medical researcher and geneticist specializing in musculoskeletal disorders at the University of Pennsylvania School of Medicine. And early diagnosis of this — and other rare diseases — is crucial, not only for treatment but to avoid diagnostic tests that can harm patients. While Nancy did finally receive a definitive diagnosis, many of the earlier diagnostic tests were actually causing more harm than good. “If you just have that in the back of your mind, that you have a vague image of what [it] is and see a patient who you think might have it,” says Dr. Shore, “to send a referral and get it confirmed, just think of the difference it would make in that family's life.” 

A patient in her mid-50s complains of foot and leg pain. She's post-menopausal with low bone density. A classic case of post-menopausal osteoporosis.Not exactly. And it won't start to become clear until it gets to the point of her having repeated metatarsal bone fractures.Let's go back a little. It's 2005. Our patient visits her family doctor complaining of pain in her legs and feet. But the discomfort she's experiencing isn't your typical aches and pains associated with aging. “She develops a lot of [foot and leg] pain … So much so that she required pain management for this pain and her gate started to become affected,” shares Dr. Katherine Dahir, a professor of medicine at Vanderbilt University, who specializes in metabolic bone disease.Her gait becomes wobbly and she's experiencing an acceleration of degenerative changes in her spine. An osteoporosis screening reveals she has low bone density. She's diagnosed with post-menopausal osteoporosis and is treated with bisphosphonates, the standard of care for patients with osteoporosis. And this is when things get much more complicated. Although all signs show an improvement in bone density, she begins to experience metatarsal bone fractures, which is highly unusual with osteoporosis. And not only does she have these unusual fractures, the fractures will not heal.  “And so that's when you need to put your thinking cap on and try and figure out, why is this patient a treatment failure?” says Dr. Dahir.To solve the case, the patient's team studies her labs and finds a missing flag. “... It was called alkaline phosphatase, which is seen in a routine chemistry panel. Back at that time, it was only flagged if it was above the normal reference range because that usually indicates liver disease, but it wasn't flagged if it was below the normal reference range because that was considered to be non-significant.” But this finding would prove to be very significant. Combined with new research at the time, it helped identify a diagnosis for this patient — showing the importance of medical research that leads to more treatment options and more hope for patients. 

Host Dr. Ashley Elliot and Dr. Kassim Javiad share an interesting case that was presented to the metabolic bone clinic as a result of excruciating foot and leg pain. They chat through the most common questions that arise when dealing with a case like this, including investigations and treatment options. 

Just a few weeks ago we shared the story of John Crowley's family and their battle with Pompe disease on Raise the Line, and in this episode, we're honored to share another remarkable story of a rare disease parent and the contributions they've made beyond their efforts to help their own loved ones.  Nick Sireau is the CEO and Chair of Trustees of the AKU Society, an award-winning patient group that helps people with Alkaptonuria (AKU), sometimes referred to as black bone disease, a rare disorder affecting both of his children. In AKU patients, a build-up of acid in the body leads to a painful breakdown of bones and joints, and serious heart complications. Nick's tireless efforts have led to some extraordinary results, including making the very first treatment for AKU available.  Nick is also Founder and Chair of Orchard, a medical charity that works to develop new and better treatments for obsessive-compulsive disorder (OCD), a misunderstood mental illness that Nick has battled for many years. Join host Shiv Gaglani for a fascinating look at the impact one parent has had on the welfare of so many, and for advice for those weighing career options in the healthcare field.  “There are hundreds, if not thousands of these ultra-rare diseases that just nobody is touching.”Mentioned in this episode:https://akusociety.org/https://www.orchardocd.org/

In this third episode of a three-episode podcast series, COR2ED and ASBMR have partnered with patient advocates Inês Alves (European Rare Bone Forum) and Tracy Hart (Osteogenesis Imperfecta Foundation) to provide rare bone disease highlights from the ASBMR 2022 Annual Meeting, focusing on the patient perspective. The experts opened the podcast with the importance of engaging diverse patient communities. Independent of geography, patients should be educated about their condition and prepared for clinical trial participation; advocacy groups play a central role in this engagement. The experts then discussed outcomes of the IMPACT survey in OI (osteogenesis imperfecta), whose extensive database (66 countries, >2000 participants) offers meaningful insights into the clinical, humanistic and economic challenges faced by OI patients around the world. Looking to advances in pre-clinical research, the experts reviewed data on nanoparticle-mediated delivery of small interfering RNA (siRNA) to targeted mutation sites, tested in an animal model of autosomal dominant osteopetrosis. As the experts note, patient communities struggle with lengthy research and development timelines for novel therapies; therefore, it’s important for advocates to keep communities informed about ongoing efforts.

In this second episode of a three-episode podcast series, COR2ED and ASBMR have partnered with Professor Eric Rush (Children’s Mercy Hospital) to provide rare bone disease highlights from ASBMR 2022 Annual Meeting. Prof. Rush opens with detailed information on fibrodysplasia ossificans progressiva (FOP): symptoms of this severe congenital condition include permanent heterotopic ossifications preceded by painful soft tissue swelling. Nearly all patients have the same ACVR1 receptor variant, and Prof. Rush shares therapy options for the disease. He then offers insights on hypochondroplasia (HCH), a developmental disorder caused by a defect in the FGFR3 gene. An animal model for HCH has been developed, in which infigratinib, a selective FGFR tyrosine kinase inhibitor, shows positive effects on growth as well as proportion. He then describes a clinical study in osteogenesis imperfects (OI), in which allogenic transplantation of fetal liver-derived mesenchymal stem cells was tested in children with type III and type IV OI. While increased bone density and height were observed, Prof. Rush cautions that both the number of study participants and the study duration were low. He closes the podcast with personal insights from the in-person Annual Meeting, including opportunities for engagement and exchange at “Meet the Professor” sessions.

In this first episode of a three-episode podcast series, COR2ED and ASBMR have partnered with Professor Anna Teti (University of L’Aquila) to provide rare bone disease highlights from the Rare Diseases Symposium that preceded the ASBMR 2022 Annual Meeting. Opening with an overview of ongoing clinical research in several rare bone diseases, Prof. Teti highlights the importance of preparing clinicians for unexpected adverse events. Notably, therapies used in the context of rare bone diseases can cause adverse events not seen if a common bone disease was treated. For osteogenesis imperfecta, she discusses a novel treatment based on umbilical cord mesenchymal stem cells. A safety study in 18 paediatric patients – three of whom received a pre-natal injection – is awaiting completion by the end of 2023. Initial safety data suggests that multiple stem cell transplantations in children with this disease is safe. Prof. Teti emphasizes the impact of achondroplasia, the most common rare bone disease, and one for which new treatments are also in development. Pharmacological treatment aims to reduce activity of the pathogenic, overactive variant of FGFR3 which causes the disease. She is confident that a treatment will be found that, at minimum, enhances quality of life in patients. Prof. Teti concludes with a review of the highly collaborative spirit of the Rare Diseases Symposium, emphasizing that patient well-being must be the driving force of research.

A new MP3 sermon from Answers in Genesis Ministries is now available on SermonAudio with the following details: Title: A T-Rex with Bone Disease? Subtitle: Answers with Ken Ham Speaker: Ken Ham Broadcaster: Answers in Genesis Ministries Event: Radio Broadcast Date: 6/23/2022 Length: 1 min.

Not only does the idea of a multiverse have problems, so do the mechanisms that supposedly caused it!

Shawn Xiang Biography Dr. Xiang is the CEO of Rarestone Group, a company building the first rare disease ecosystem in China. Dr. Xiang has more than 15 years of leadership experience in pharmaceutical and medical device industries. Prior to RareStone, Shawn was the General Manager of Greater China and Emerging Asia Region at Abbott Diabetes Care, where he led his team and successfully launched FreeStyle Libre in China, Korea and Southeast Asia markets and achieved hyper-growth consecutively over the years. Shawn also led his team to build an ecosystem for patients living with Type 1 Diabetes, through strong collaboration with patient organizations, governments and industry partners. Prior to Abbott, Shawn served as the Franchise Head of Bone Disease and Respiratory Disease at Novartis China. He also served as the Director of Global Pharma Strategy at Novartis Global in Switzerland. Earlier in his career, Shawn was an Engagement Manager at McKinsey & Co. in the USA. Dr. Xiang holds a PhD degree from Yale University and a BS degree from Peking University. On this episode of Behind Biotech, we discussed with Shawn: Common misconceptions about rare disease in China Recent catalysts which catapulted rare disease development in China Rarestone's unique model which combines a traditional biotech with a digital patient ecosystem

Deer seeks refuge in a church; Fewer Americans believe Jesus' teaching about hell; Apple pleases Chinese government by removing Bible and Quran apps; Paleontologists capitalize on Denisovan bone fragments to tell another deep-time story; Researchers find disease when they use dual-energy computed tomography (DECT) to scan a T-rex jawbone . . . and other stories reviewed during this December 13, 2021, broadcast of Answers News. - - - - - - - - - - - God saw all that he had made, and it was very good. And there was evening, and there was morning—the sixth day. - - - - - - - - - - - Genesis 1:31 Articles: Video shows buck taking shelter inside Michigan church on state's first day of hunting season (video included) https://www.cbsnews.com/news/buck-church-hunting-season-michigan/ Most Catholics, mainline Protestants say faith in God not required to enter Heaven: study https://www.christianpost.com/news/most-catholics-say-faith-in-god-not-required-to-get-into-heaven.html Apple removes Bible, Quran apps in China https://www.mnnonline.org/news/apple-removes-bible-quran-apps-in-china/ Oldest-known fossils of mysterious human lineage uncovered in Siberian cave https://www.livescience.com/oldest-denisovan-fossils-in-siberian-cave CT uncovers bone disease in Tyrannosaurus rex jaw https://www.sciencedaily.com/releases/2021/12/211201085141.htm Norway's postal service commercial: Daddy kissing Santa Claus https://nypost.com/2021/11/24/daddy-caught-kissing-santa-claus-in-new-postal-service-commercial/ Social Media Star Who Was Censored for Sharing Biblical Beliefs on Marriage Wins Big Ruling https://www1.cbn.com/cbnnews/world/2021/november/social-media-star-who-was-censored-for-sharing-biblical-beliefs-on-marriage-wins-big-ruling The first ‘living robots' that can REPRODUCE: Microscopic organisms made from frog cells assemble ‘babies' in their Pac Man-shped mouths- in breakthrough that could one day be used to destroy cancer cells. https://www.dailymail.co.uk/sciencetech/article-10254773/Scientists-build-living-robots-reproduce.html - - - - - - - - - - - Photo by: Huang Yingone unsplash.com/photos/7_yzujmD8AE --- Send in a voice message: https://anchor.fm/answerstv/message Support this podcast: https://anchor.fm/answerstv/support

We have partnered with international experts to provide rare bone disease highlights from ASBMR 2021. This is the final episode in a series of four podcasts, in this episode Dr Eekhoff and Dr Rush discuss their rare bone disease highlights from the meeting.

We have partnered with international experts to provide rare bone diseases highlights from ASBMR 2021. This is the third episode in a series of four podcasts. In this episode Charlene Waldman (RBD Alliance) and Inês Alves (European Rare Bone Forum) discuss their highlights.

We have partnered with international experts to provide rare bone diseases highlights from ASBMR 2021. This is the second in a series of four podcasts. In this episode Dr Oliver Semler has selected and discusses his highlights.

We have partnered with international experts to provide rare bone disease highlights from ASBMR 2021. This is the first episode in a series of four podcasts, in this episode Dr Mughal and Dr Javaid discuss their highlights.

Dr. Jeffrey Mechanik, the man who literally wrote two books on molecular nutrition, joins Marcus Antebi in a follow up to episode #61 with Gary Taubes. In episode #61 Gary and Marcus get "heated" with each other over the KETO diet. (Marcus is an outspoken opponent of the KETO diet.) Gary Taubs is a huge proponent of this dietary pattern and author of several books on the subject. Episode #62, Dr. Mechanick clarifies and illuminates Marcus' objections to this DIET pattern. Both episodes are great fun!   Dr. Mechanick is Professor of Medicine and Medical Director of the Marie-Josee and Henry R. Kravis Center for Cardiovascular Health at Mount Sinai Heart, and in the Cardiovascular Institute and Division of Cardiology, and Director of Metabolic Support in the Division of Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai. 

Metabolic Bone Diseases are commonly seen by General Practitioners in a Primary Care setting. In today's episode, our President Davog McCaffrey discusses the  Clinical Features, Investigations, Diagnosis and Management of 3 main Metabolic Bone Diseases - Osteoporosis, Osteomalacia and Paget's Disease. 

Silke, Chris and Bertrand discuss bone protective therapy and bone targeted therapy.

Stephen Knohl, MD, is a Professor of Medicine, Residency Program Director of Internal Medicine and Vice Chair of Education at SUNY Upstate Medical University. Dr. Knohl completed his medical school and residency in internal medicine and then pursued a fellowship in Nephrology from SUNY Upstate. Dr. Knohl's research interests include Genetic Hypercalciurias, Nephrolithiasis and Bone Disease in CKD. He is passionate about teaching communication skills to his residents, and has developed a program called 'Learning to T.A.L.K.' (Treat All Like Kin) to teach medical residents to be more effective communicators, and ultimately better physicians. It's okay not to know. That is what makes us human. But according to Dr. Stephen Knohl, it's not okay not to know the second time we're asked. That is what defines character. Today, we learn about the strengths we have by learning to be introspective. When we are passionate about our career, we must prove it by devoting ourselves to filling in our knowledge gaps, being humble about feedback, and being willing to course correct throughout our career.  Dr. Knohl also shares his unique perspective on mentorship: Mentorship should exist on a personal and professional level, but it is the mentor's responsibility to take it to a personal level.  A strong mentorship should take the initiative to show their mentees that they are invested in them personally. Because after all, we're human. And in order to solve problems and cure disease in medicine, we must bring our whole selves to the equation. Pearls of Wisdom: 1. You must learn how to prioritize your career in order to achieve a healthy work/life balance. Study hard, but find things that make you whole, and do things that are enriching. 2. In finding a great mentor, look for a “twinkle” and trust your gut. Mentorship should extend beyond your professional self, and strong mentors will connect and invest in you personally. 3. When we approach patients, we should think of ourselves as actors: We need to be prepared for every situation, and we need to put the patient first.

Thank you for joining us for our 2nd Cabral HouseCall of the weekend! I’m looking forward to sharing with you some of our community’s questions that have come in over the past few weeks… Let’s get started!    Anthony: Been taking EN's Digestive Enzyme for almost a year now daily. I understand that the body can become reliant and produce less of its own enzymes because of exogenous enzymes. Given that I did the CBO and have a clean OAT in the re-test, with the occasional reflux/burping -- what are the best ways to wean off so I don't have to rely on them? Currently taking 1 every meal and would prefer to not carry them around and be "dependent." Thank you Dr. Cabral! Deb: What approach can be made to calm low back nerve pain? I have a S1-S2 that is degenerating and can press the nerves in the lower back against my spine. Western medicine wants to do back surgery that had a 60% chance of 80% or more relief. This is not an option for me. I still exercise and try to eat right. But at night have nerve pain that can have a dull spasm running up and down my legs which will wake me from a sound sleep. Need your thoughts Salil: Do you have any free courses? Jimmy: Hi Dr Cabral, I had a CT scan on my spine (not because of any real pain, it's a long story but basically I had one) and it came back that I had a minor wedge fracture of the C6 and C7 spine.The Doctor said this could be from degenerative bone disease. Every now an then I will get a shooting pain in my neck and its very painful, but it happens very infrequently. I just wondered if there is anything I could do to combat this, apparently it's normal as we get older that the spine can start to decay, I wonder if it's my posture of diet that's making it worse though? I am only in my twenties so not old. Any tips on how to heal or combat this? Thanks Dr.Cabral Donna: Dr. Cabral, I appreciate you being a voice to educate thousands of people so that they can make informed decision to improve their overall health and to stay healthy.I've been watching The Truth About Vaccines. Could you do a future podcast to give us the understanding between being immunized or vaccinated? Also, some insight into the ingredients in vaccines and how they can play a role in our health. Finally, can you teach us how to detox our bodies from any harmful substances that may be injected into us from vaccines whether we receive them by choice or by forced mandates. Grateful to hear your knowledge on this topic. Sincerely, DC Anonymous: Hi Dr. Cabral, Thank you for all you do. I have three very embarrassing symptoms that have been bothering me off and on for years. I don’t know if they’re related. The first is a bad smell coming from my vaginal area. I try to follow all recommended advice (breathable fabrics, loose fitting clothes, etc.) but it starts almost immediately after showering and won’t go away. I also have extremely smelly gas. It will last for a few days to a week. It usually comes back every few weeks. I haven’t been able to connect it back with a particular food.Lastly, I have a lot of pain/itchiness around my anus. I have switched to gentle soap, using a bidet and hypo-allergenic toilet paper. It usually bothers me the most after I wipe with toilet paper but will also irritate me at night.I look forward to any insight you may have! James: Hi Dr Cabral, I asked a question a while back about healthy bulking and your answer really helped. Vata body type here so had to be a bit more diligent when deciding how to bulk, anyway, it's going well. I'll be transitioning into a cut in a few months when I reached my desired pre-cut weight goal, and my question was simply a reverse of my old one: How can I cut effectively and efficiently? There's not too much information out there on how to cut, mainly only how to bulk so I wondered if you could point me in the right direction on how I should cut for best results, obviously I want to lose mainly fat and very little muscle. I've heard just go on a slight calorie deficit? Is it that simple? I should mainly be reducing carbs right? Any tips? Thanks Doc, James Thank you for tuning into this weekend’s Cabral HouseCalls and be sure to check back tomorrow for our Mindset & Motivation Monday show to get your week started off right! - - - Show Notes & Resources:  http://StephenCabral.com/1584 - - - Dr. Cabral's New Book, The Rain Barrel Effect https://amzn.to/2H0W7Ge - - - Join the Community & Get Your Questions Answered: http://CabralSupportGroup.com - - -   Dr. Cabral’s Most Popular Supplements: > “The Dr. Cabral Daily Protocol” (This is what Dr. Cabral does every day!) - - - > Dr. Cabral Detox  (The fastest way to get well, lose weight, and feel great!) - - - > Daily Nutritional Support Shake  (#1 “All-in-One recommendation in my practice) - - - > Daily Fruit & Vegetables Blend  (22 organic fruit & vegetables “greens powder”) - - - > CBD Oil  (Full-spectrum, 3rd part-tested & organically grown) - - - > Candida/Bacterial Overgrowth, Leaky Gut, Parasite & Speciality Supplement Packages - - - > See All Supplements: https://equilibriumnutrition.com/collections/supplements  - - -   Dr. Cabral’s Most Popular At-Home Lab Tests: > Hair Tissue Mineral Analysis (Test for mineral imbalances & heavy metal toxicity) - - - > Organic Acids Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Thyroid + Adrenal + Hormone Test  (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Adrenal + Hormone Test (Run your adrenal & hormone levels) - - - > Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Omega-3 Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - > Stool Test (Use this test to uncover any bacterial, h. Pylori, or parasite overgrowth) - - - > Genetic Test (Use the #1 lab test to unlocking your DNA and what it means in terms of wellness, weight loss & anti-aging) - - - > Dr. Cabral’s “Big 5” Lab Tests (This package includes the 5 labs Dr. Cabral recommends all people run in his private practice) - - -

Simon Dharmakirthi is a special guy in many ways. He loves the Orlando Magic more than anyone I know and his heart is always in the right place. He was born with the rarest bone disease in the world (Osteogenesis imperfecta) but he doesn't let that get him down. I wanted to chat with him to share his amazing story of survival and joy. He shares some amazing advice that ANYONE can learn from. He inspires me with his incredible attitude and some of the knowledge he gives for when you are down will surely lift you up and get you going in the right direction.

i'm getting real and raw in this episode telling you about my biggest health struggle that ultimately taught me to look more at the heart and realize that we're all struggling with something. no, life isn't always candy colored and jolly, but we can make it better as we seek to know others, sending love and support.sign up for my sweet list, aka my email listwww.katrinaberg.com

In this episode we cover general questions our viewers may have about the disease. Such as: “What is Osteopetrosis or Marble Bone Disease?” “What causes it?” “Who is affected?” Etc. This is one of four episodes we will produce to help you understand this complex and rare genetic disease.

Metabolic Bone Disease, or MBD, is one of the chameleon world’s leading causes of death. And it is completely preventable. Join me in the “Scare Away MBD” campaign and let’s make MBD a story we tell from the chameleon dark ages. In this first episode we are joined by Dr. Rob Coke, the head veterinarian from the San Antonio Zoo who explains what MBD is and what is going on.

Dan Nicholls discusses red flags and metastatic bone disease with Laura Finucane

Dr. Ruben Niesvizky discusses newer approaches for imaging in patients who have multiple myeloma with bone disease, including the benefits of combining modalities such MRI and PET scan.

Prof Terpos speaks with ecancer at the 16th International Myeloma Workshop about late breaking data from IMW 2017, assessing the efficacy and safety of denosumab compared with zoledronic Acid in newly diagnosed symptomatic myeloma patients. Targeting RANKL, this Phase III study with denosumab met its primary endpoint of non-inferiority to zoledronic Acid in delaying time to first on-study skeletal related events in patients with newly diagnosed myeloma. Denosumab also showed comparable overall survival and for the first time superior PFS compared with zoledronic Acid. Renal adverse events were also greatly reduced with denosumab. These results and the fact that denosumab can be administered subcutaneously, lead to the suggestion that it will become a new standard of care for the management of bone disease in multiple myeloma.

Prof Terpos speaks with ecancer at the 16th International Myeloma Workshop about the bone related complications seen with myeloma patients (MM) and how these are managed. Approximately 80% of MM patients present with detectable lesions of osteolytic bone disease, meaning it is a critical consideration to the overall treatment and management of patients with multiple myeloma. The current management of MM bone disease is based on the use of bisphosphonates and mainly Zoledronic Acid due to favourable study results. In some patients with side effects such as renal impairments it is recommended to stop bisphosphonates, however new studies involving Denosumab suggest that a solution may be on its way.

​Prof Pieter Sonneveld (University Hospital Rotterdam, Netherlands) chairs a roundtable discussion for ecancer at the 16th International Myeloma Workshop in Delhi, India. Focusing on newly diagnosed multiple myeloma (NDMM) and the management of bone disease, he is joined by Prof Michele Cavo (Seràgnoli Institute of Hematology, Bologna, Italy), Dr Peter Voorhees (Levine Cancer Institute, North Carolina, USA) and Professor Evangelos Terpos (University of Athens, Greece). First discussed was the treatment of symptomatic transplant-eligible multiple myeloma patients, with Prof Cavo suggesting that although trials continue to explore old and new agents, high dose melphalan supported by ASCT should remain the standard of care for the treatment of fit NDMM patients. Trials assessing these agents were discussed, such as the StaMINA trial presented at ASH 2016, which showed that the addition of bortezomib, lenalidomide (Len) and dexamethasone (RVD) consolidation or a second Autologous Hematopoietic Cell Transplant (autoCHT) was not superior to a single autoHCT followed by Len maintenance in the upfront treatment of MM. Moving on to asymptomatic patients, Dr Voorhees provided an overview of the treatment of smoldering myeloma (SM). Discussion focused on the evolving therapeutic landscape in SM, with agents such as elotuzumab and checkpoint inhibitors pembrolizumab and nivolumab showing promise. Proteasome inhibition was also discussed, looking at the CESAR and ASCENT trials, with Dr Voorhees commenting that with the latter it will be “interesting to see if this leads to cure”. The panel then focussed on the management of bone disease – the most common complication of multiple myeloma with 80% of patients presenting with detectable lesions. Bisphosphonates such as zoledronic acid are the current mainstay for the treatment of myeloma bone disease, with several novel agents, including denosumab, showing positive results. These advances show that for NDMM patients the future is promising for both first-line treatment options and the management of common complications.

Prof Terpos speaks with ecancer at EHA 2017 about the comparative trial of denosumab and zoledronic acid for skeletal disease in new multiple myeloma diagnoses. Prof Terpos describes how, from a randomised trial of 1718 patients, the progression to skeletal disease at 15 months was equivalent in both arms, with denosumab meeting its non-inferiority goals. Those receiving denosumab were also found to have reduced renal toxicity, and, in an exploratory assessment, progression free survival was also favourable.

Tom Nickolas, MD, MS

Metabolic bone diseases are disorders of bone strength, and can sometimes be caused by abnormalities of minerals. Often patients undergoing cancer treatments may have some side effects involving their bone density.  City of Hope is opening a Metabolic Bone Disease Center to offer evaluation and treatment of patients with metabolic bone diseases. Osteoporosis patients will also find the help they are looking for at City of Hope. Azar Khosravi, MD, endocrinologist at City of Hope, is here to help you better understand Metabolic Bone Diseases and how City of Hope is there to help you to care for your bones.  

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