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On tonight's show, we will be discussing the newly formed partnership between Kids to Love & iXpressGenes! To share about this partnership, I'll have Kids to Love founder Lee Marshall & iXpressGenes CEO John Schmitt. As part of their trauma therapy program, a new test developed by iXpressGenes, an associate company at HudsonAlpha Institute for Biotechnology, will enable Kids to Love to tailor a client's therapy in order to get them the most effective treatment – combining cutting-edge science and compassionate care to help them heal.
Alabama's ecosystem of innovation is built on the strength of its entrepreneurs, workforce, policymakers, and community leaders. Leading economic development at HudsonAlpha Institute for Biotechnology, Carter Wells has long worked at the intersection of these stakeholders, fueling innovation, collaboration, and impact across 45 biotech companies in the state. In this custom episode, learn how Carter connects Alabama's best institutions, organizations, and people behind HudsonAlpha's mission — and how Alabama creates an ecosystem for this mission to thrive.
Alabama's ecosystem of innovation is built on the strength of its entrepreneurs, workforce, policymakers, and community leaders. Leading economic development at HudsonAlpha Institute for Biotechnology, Carter Wells has long worked at the intersection of these stakeholders, fueling innovation, collaboration, and impact across 45 biotech companies in the state. In this custom episode, learn how Carter connects Alabama's best institutions, organizations, and people behind HudsonAlpha's mission — and how Alabama creates an ecosystem for this mission to thrive.
Dr. Richard M. Myers is the President, Science Director, and a Faculty Investigator at HudsonAlpha Institute for Biotechnology. In addition, Rick is an adjunct faculty member in the Department of Genetics at the University of Alabama at Birmingham. At work, Rick balances being a scientist, running his research lab, and managing administrative responsibilities as head of a research institute. His research focuses on genetics and genomics. In particular, Rick aims to better understand how our genes and their expression contribute to our traits, health, and disease. He also examines how genes and gene expression can be regulated. Outside of science, Rick enjoys spending time with his family, including his two adult children. One currently lives in Seattle and the other lives in London. In addition, Rick's hobbies include cooking, gardening, and woodworking. He received is B.S. in biochemistry from the University of Alabama and his Ph.D. in biochemistry from the University of California, Berkeley. Afterwards, Rick conducted postdoctoral research at Harvard University. He served on the faculty at the University of California, San Francisco as well as at Stanford University where he contributed substantially to the efforts to sequence the human genome as part of the Human Genome Project. Rick accepted his current position at HudsonAlpha in 2008. He has received many awards and honors throughout his career including an Honorary Doctorate Degree from the University of Alabama, the Blount Initiative Award from the University of Alabama, the Pritzker Foundation Award from the University of Michigan, and the Darden Lecture Award from the University of Alabama. He has also been named a Fellow of the American Association for the Advancement of Science. In this interview, Rick discusses his experiences in life and science.
Neil Lamb, President of the HudsonAlpha Institute for Biotechnology, discusses his journey to HudsonAlpha and the growth and impact of the institute. The conversation explores the vision of HudsonAlpha and its role in the growth of Huntsville, Alabama. It also delves into the expansion of HudsonAlpha's model to other areas, such as the Wiregrass region, and the focus on research, economic development, and education. We also discuss the unique model they have with associate companies that work alongside the institute.Our Presenting SponsorReLogic is an Engineering, Aerospace, and Technology company dedicated to solving our Nation's toughest defense problems while investing in the bright minds of Huntsville. ReLogic is excited to be a part of the innovation and continued growth of the Huntsville community. Visit their website today to see what they are excited about at https://www.relogicresearch.com
Grant Hershbine is the Director of the Battle of the Buffalo, an annual wing festival put on by the brothers of the Alpha Tau Omega fraternity at The University of Alabama in Huntsville. Battle of the Buffalo was created in honor of our beloved fallen brother, Paul “Fish” Salmon. Since losing his battle with cancer in 2007, our chapter has raised more than $230,000 for Russel Hill Cancer Foundation and $42,000 for HudsonAlpha Institute for Biotechnology. Grant is set to graduate in May from the University of Alabama-Huntsville and then plans to attend law school in the fall. To purchase tickets or for more information, please visit us at https://BattleoftheBuffalo.org Host/Interviewer: M. Troy Bye, Owner, Our Town Podcast Website: https://ourtownpodcast.net Spotify Channel: https://spoti.fi/3QtpT8z Audio available on all platforms - just search for "Our Town Podcast" Follow us on social media: LinkedIn: http://bit.ly/41rlgTt Facebook: https://bit.ly/ourtownpodcast Instagram: https://www.instagram.com/ourtownpodcast/ Episode Timeline: 00:00 Start 00:10 Intro | 113 Recap 01:51 Grant and UAH 05:36 Paul Salmon & Fundraisers 09:44 Acute Myeloid Leukemia 12:36 Attracting Interest | The Wings 16:00 Festival Overview 19:40 Vendors & Logistics 24:40 The Rounds & Charitable Giving 29:06 ATO Committees | Recruiting 32:10 IG Walkthrough 35:55 Media Blast 38:00 Grant's Growth 43:15 The Salmon's 48:10 Congressional Award 57:03 Law School & Initial Career 01:00:15 Boys State 01:04:25 Over the Edge 01:07:00 ATO 01:11:10 Quick 6 01:18:05 Final Thoughts --- Support this podcast: https://podcasters.spotify.com/pod/show/m-troy-bye/support
What a great time recording with HudsonAlpha Institute! We talked about genomics with Dr. Neil Lamb and Director Dean Mitchell and how understanding DNA can be a key to success for medical treatments, dietary adjustments and even cancer prevention. Check out the conversation about Hudson Alpha Institute for Biotechnology now!
Right now, our natural rubber comes from just one tree species: Hevea brasiliensis. It's great at producing latex that becomes rubber, but it's vulnerable to disease and climate shifts. So researchers are looking into a desert shrub that's native to North America: guayule. This episode was made in collaboration with our friends at the HudsonAlpha Institute for Biotechnology.Links from this episode:Submit your own proposal to work with the JGI : http://jointgeno.me/proposals Join us at the 2023 JGI User Meeting: http://jointgeno.me/JGI2023 Episode TranscriptHudsonAlpha Institute's Tiny Expeditions PodcastGuayule: Can genetics create a natural US rubber source?Guayule Project in the JGI's Approved Proposals of 2022Our contact info:Twitter: @JGIEmail: jgi-comms at lbl dot gov
In the United States, shortly after birth, every newborn receives a series of screening tests to identify treatable diseases. Every September we celebrate this amazing system of research, public health, and clinical care that saves the lives of babies every day with Newborn Screening Awareness month. Neonatal screening also occurs around the world and many countries are working on innovative approaches to use genomics to significantly expand, or improve, our ability to screen, diagnose, and treat hundreds if not thousands of additional diseases. We are excited to feature one of these innovators on the Newborn Screening Spotlight, Dr. David Bick who, is the Principal Clinician for the Newborn Genomes Programme at Genomics England. Genomics England is undertaking an effort to include genomics in neonatal screening. Prior to his work in England, he was the Chief Medical Officer and a faculty investigator at the HudsonAlpha Institute for Biotechnology. He came to HudsonAlpha from the Medical College of Wisconsin where he was Professor in the Department of Pediatrics and the Department of Obstetrics & Gynecology at the Medical College of Wisconsin. At the Medical College of Wisconsin he was the Director of the Clinical Sequencing Laboratory, Director of the Advanced Genomics Laboratory at Children's Hospital of Wisconsin, Medical Director of the Genetics Clinic at Children's Hospital of Wisconsin, and Chief of the Division of Genetics in the Department of Pediatrics at Medical College of Wisconsin. Dr. Bick received his medical degree from George Washington University School of Medicine in 1981 and completed his residency in Pediatrics at Yale-New Haven Hospital in New Haven, CT. At the Yale University School of Medicine, Dr. Bick completed a fellowship in Human Genetics and Pediatrics in 1986, followed by a post-doctoral research fellowship in Human Genetics in 1987. Dr. Bick is board certified in Pediatrics, Clinical Genetics, and Clinical Molecular Genetics. He is a leader in the field of genomic medicine and has published numerous peer-reviewed articles, chapters, and reviews. Dr. Bick's laboratories at the Medical College of Wisconsin and Children's Hospital of Wisconsin were the first in the world to offer whole genome sequencing as a clinical test. He also developed the first Genomic Medicine Clinic in the United States. Join us as we learn about the role of genomic sequencing of newborns. Podcast Interview Questions for Dr. David Bick Bick, thank you for joining us for the newborn screening SPOTlight podcast, we would love for our listeners to get know you and the impact you've made on clinical genomic medicine, newborn screening research. You're a pediatrician, researcher, and leader in genomic medicine. How did you get involve with newborn screening research? You were a faculty in the Department of Pediatrics and the Department of Obstetrics & Gynecology at the Medical College of Wisconsin, where your laboratory was the first to offer whole genome sequencing as a clinical test. What advice can you share for others who are interested in proposing the implementation of genome sequencing in their hospitals? You have now moved to the UK to be the Principal Clinician for the Newborn Genomes Programme at Genomics England. Can you tell our listeners more about this program? From your experiences at the Screen4Care consortium and the European collaborative Innovative Medicines Initiative, what are lessons that we in the US can learn from? In your recent publication titled “Newborn Screening by Genomic Sequencing: Opportunities and Challenges,” you describe the need for “standardization of data formats and analytical approaches within and even between health systems” to support newborn screening by genome sequencing. There are differences between the UK and US health care delivery system. How do you envision this process of standardization in the UK? How can the US with its various health care delivery systems and health insurance plans be able to adopt a similar approach? Are you involved in training the next generation of pediatrician nd what do you tell them about newborn screening research? What role could NBSTRN play to support international efforts in advancing rare disease research and screening for diseases for which early intervention may improve outcome? What does NBS research mean to you?
Tiny Expeditions - A Podcast about Genetics, DNA and Inheritance
We're sorry that we couldn't bring you a new episode last week, but sometimes life happens. Please enjoy this bonus episode starring Dr. Neil Lamb, the new president of HudsonAlpha Institute for Biotechnology. In this episode, Dr. Lamb explains the many flavors of genetic tests that are out there and what you can reliably learn from each of them.
Tiny Expeditions - A Podcast about Genetics, DNA and Inheritance
Learn how two scientists who set out to immortalize Auburn University's Toomer's Oak trees actually ended up creating a college class that makes hands-on science experiences accessible to all students. To go behind the scenes to hear additional audio and see pictures from the lab, visit Will science emerge as the real champion in a football rivalry gone bad? – HudsonAlpha Institute for Biotechnology
Here’s a title for you. Chief Genomics Officer. Today’s guest is also the VP of Genomic Medicine and a faculty investigator at the HudsonAlpha Institute for Biotechnology.
Dr. Richard M. Myers is the President, Science Director, and a Faculty Investigator at HudsonAlpha Institute for Biotechnology. In addition, Rick is an adjunct faculty member in the Department of Genetics at the University of Alabama at Birmingham. He received is B.S. in biochemistry from the University of Alabama and his Ph.D. in biochemistry from the University of California, Berkeley. Afterwards, Rick conducted postdoctoral research at Harvard University. He served on the faculty at the University of California, San Francisco as well as at Stanford University where he contributed substantially to the efforts to sequence the human genome as part of the Human Genome Project. Rick accepted his current position at HudsonAlpha in 2008. He has received many awards and honors throughout his career including an Honorary Doctorate Degree from the University of Alabama, the Blount Initiative Award from the University of Alabama, the Pritzker Foundation Award from the University of Michigan, and the Darden Lecture Award from the University of Alabama. He has also been named a Fellow of the American Association for the Advancement of Science. Rick has joined us today to talk about his experiences in life and science.
In this podcast from CHI, on May 11th, 2017 Liz Worthey, Faculty Investigator and Director at HudsonAlpha Institute for Biotechnology sat down to discuss her work in whole genome sequencing to diagnose and monitor rare diseases. She discusses her team’s work with standardizing NGS tests, utilizing sequencing as a diagnostic test, and challenges to making whole genome sequencing standard of care in clinical practice. To learn more, please visit http://www.NextGenerationDx.com/NGS-Based-Assays/
Liz Worthey of HudsonAlpha Institute for Biotechnology speaks to Cambridge Healthtech Institute on March 9, 2017. She will be a featured presenter during a shared session for the Clinical Genomics and Data Security conferences at Bio-IT World Conference & Expo, May 23-25 in Boston, Massachusetts. For more information, please visit http://www.Bio-ITworldExpo.com/
This week, an interview with Howard Jacob, PhD, principal investigator and executive vice president for genomic medicine at HudsonAlpha Institute for Biotechnology (starts at 5'30")describing the potential for personalized genomic sequencing and analysis in the identification of rare undiagnosed and misdiagnosed disease. A headline featuring research on how dogs process words mentioned a video of dogs in MRI machines; see the dogs at http://www.sciencemag.org/news/2016/08/video-your-dog-understands-more-you-think. Host:Beth Bennett Producer:Beth Bennett Engineer:Maeve Conran Additional Contributions:Joel Parker Executive Producer:Susan Moran Listen to the show:
How Alan Turing's Reaction-Diffusion Model Simulates Patterns in Nature Thanks to http://www.audible.com/minuteearth for sponsoring this video. Asparagus Pee Survey Results: https://goo.gl/8x7abL ___________________________________________ If you liked this video, we think you might also like this: Reaction Diffusion Simulation (Gray-Scott model) https://pmneila.github.io/jsexp/grayscott/ ___________________________________________ Credits (and Twitter handles): Script Writer: Rachel Becker (@RA_Becks) Script Editor: Emily Elert (@eelert) Video Illustrator: Ever Salazar (@eversalazar) Video Director: Emily Elert (@eelert) Video Narrator: Emily Elert (@eelert) With Contributions From: Henry Reich, Alex Reich, Kate Yoshida, Omkar Bhagat, Peter Reich, David Goldenberg Music by: Nathaniel Schroeder: http://www.soundcloud.com/drschroeder Also, special thanks to the following scientists: Greg Barsh: Investigator, HudsonAlpha Institute for Biotechnology (http://goo.gl/RMD8o9) Jeremy Green: Professor of developmental biology, King’s College London (https://goo.gl/Qcn8Ay) Thomas Hiscock: Graduate student in systems biology, Harvard University (http://goo.gl/RbAWIy) Shigeru Kondo: Professor, Osaka University (http://goo.gl/uQ2wYO) James Sharpe: Coordinator of EMBL-CRG Systems Biology Unit and ICREA research professor (http://goo.gl/QCGul8) Ian Stewart: Emeritus professor of mathematics, University of Warwick and author of The Mathematics of Life (http://goo.gl/rGR1R0) Thomas Woolley: Postdoctoral scientist, St John's College Oxford (http://goo.gl/B4FZNn) Image Credits: - Mouse palate images provided courtesy of Jeremy Green, King’s College London. - Digit patterns image provided courtesy of Luciano Marcon and Jelena Raspopovic. - Angelfish and zebrafish images provided courtesy of Shigeru Kondo. _________________________________________ Subscribe to MinuteEarth on YouTube: http://goo.gl/EpIDGd Support us on Patreon: https://goo.gl/ZVgLQZ Facebook: http://goo.gl/FpAvo6 Twitter: http://goo.gl/Y1aWVC itunes: https://goo.gl/sfwS6n ___________________________________________ Here are some handy keywords to get your googling started: Reaction-diffusion system: A hypothetical system in which multiple chemical substances diffuse through a defined space at different rates and react with one another, thereby generating a pattern. Turing pattern: A periodic pattern that forms in a space where the initial distribution of ‘activator’ and ‘inhibitor’ is the same. Morphogenesis: The processes during development that give rise to the form or shape of the organism or a structure Alan Turing: Alan Turing was a British mathematician and the father of modern computer science. During World War II, he broke Germany’s Enigma code used to encrypt communications. ____________________ References: Economou, A. D., Ohazama, A., Porntaveetus, T., Sharpe, P. T., Kondo, S., Basson, M. A., … Green, J. B. A. (2012). Periodic stripe formation by a Turing-mechanism operating at growth zones in the mammalian palate. Nature Genetics, 44(3), 348–351. http://doi.org/10.1038/ng.1090 Economou, A. D., & Green, J. B. (2014). Modelling from the experimental developmental biologists viewpoint. Seminars in Cell & Developmental Biology, 35, 58-65. doi:10.1016/j.semcdb.2014.07.006 Green, J. B., & Sharpe, J. (2015). Positional information and reaction-diffusion: Two big ideas in developmental biology combine.Development, 142(7), 1203-1211. doi:10.1242/dev.114991 Kimura, Y. T. (2016, May 24). The mathematics of patterns. Retrieved from http://www.theshapeofmath.com/princeton/dynsys Kimura, Y. T. (2014). The Mathematics of Patterns: The modeling and analysis of reaction-diffusion equations (Thesis, Princeton University). Http://www.pacm.princeton.edu/documents/Kimura.pdf. Kondo, S., & Asai, R. (1995). A reaction-diffusion wave on the skin of the marine angelfish Pomacanthus. Nature, 376(6543), 765-768. doi:10.1038/376765a0 Kondo, S., & Miura, T. (2010). Reaction-Diffusion Model as a Framework for Understanding Biological Pattern Formation. Science, 329(5999), 1616-1620. doi:10.1126/science.1179047 Marcon, L., & Sharpe, J. (2012). Turing patterns in development: What about the horse part? Current Opinion in Genetics & Development, 22(6), 578-584. doi:10.1016/j.gde.2012.11.013 Raspopovic, J., Marcon, L., Russo, L., & Sharpe, J. (2014). Digit patterning is controlled by a Bmp-Sox9-Wnt Turing network modulated by morphogen gradients. Science, 345(6196), 566-570. doi:10.1126/science.1252960 Stewart, I. (2012). The mathematics of life. Philadelphia, PA: Basic Books. (https://goo.gl/IOagrs) Turing, A. M. (1952). The Chemical Basis of Morphogenesis. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 237(641), 37-72. Retrieved from http://www.dna.caltech.edu/courses/cs191/paperscs191/turing.pdf
Howard Jacob understands the value of whole genome sequencing as a diagnostic tool. Jacob and his team were the first to use the technology to diagnose a child with an ultra-rare disease, which allowed doctors to save the boy’s life. Jacob, now chief medical genomics officer of HudsonAlpha Institute for Biotechnology, is working to use whole genome sequencing to find answers for other undiagnosed patients and expand the technology’s use as a clinical tool. We spoke to Jacob about the use of whole genome sequencing in the clinic, how it’s changing the way patients with rare diseases are treated, and the value of a diagnosis even in the absence of an available treatment.