Research program for sequencing the human genome
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Adam Rutherford is a science broadcaster, and author of A Brief History of Everyone Who Ever Lived, which transformed the way we think about human history. By using genetics to uncover the story of our species, it offered a thrilling new perspective on who we are and where we came from. David Olusoga is an award winning author and historian, whose work includes the TV series and book Black & British: A Forgotten History and the landmark BBC arts series Civilizations. In July 2026 they came to the Intelligence Squared stage to mark the tenth anniversary of A Brief History of Everyone Who Ever Lived. Together, they explored how advances in DNA research have transformed our understanding of human history, and discussed what a decade of new discoveries has revealed about our past. From Neanderthals to the plague, from redheads to race, from evolution to epigenetics, they discussed what our genes can tell us about human history and our ancestors. Together, they dispelled some common myths, challenging misconceptions about race and ancestry, and considered the profound consequences of the Human Genome Project. --- If you'd like to become a Member and get access to all our full conversations, plus all of our Members-only content, just visit intelligencesquared.com/membership to find out more. For £4.99 per month you'll also receive: - Full-length and ad-free Intelligence Squared episodes, wherever you get your podcasts - Bonus Intelligence Squared podcasts, curated feeds and members exclusive series - 15% discount on livestreams and in-person tickets for all Intelligence Squared events ... Or Subscribe on Apple for £4.99: - Full-length and ad-free Intelligence Squared podcasts - Bonus Intelligence Squared podcasts, curated feeds and members exclusive series … Already a subscriber? Thank you for supporting our mission to foster honest debate and compelling conversations! Visit intelligencesquared.com to explore all your benefits including ad-free podcasts, exclusive bonus content and early access. … Subscribe to our newsletter here to hear about our latest events, discounts and much more. https://www.intelligencesquared.com/newsletter-signup/ Learn more about your ad choices. Visit podcastchoices.com/adchoices Learn more about your ad choices. Visit podcastchoices.com/adchoices
Adam Rutherford is a science broadcaster, and author of A Brief History of Everyone Who Ever Lived, which transformed the way we think about human history. By using genetics to uncover the story of our species, it offered a thrilling new perspective on who we are and where we came from. David Olusoga is an award winning author and historian, whose work includes the TV series and book Black & British: A Forgotten History and the landmark BBC arts series Civilizations. In July 2026 they came to the Intelligence Squared stage to mark the tenth anniversary of A Brief History of Everyone Who Ever Lived. Together, they explored how advances in DNA research have transformed our understanding of human history, and discussed what a decade of new discoveries has revealed about our past. From Neanderthals to the plague, from redheads to race, from evolution to epigenetics, they discussed what our genes can tell us about human history and our ancestors. Together, they dispelled some common myths, challenging misconceptions about race and ancestry, and considered the profound consequences of the Human Genome Project. Learn more about your ad choices. Visit podcastchoices.com/adchoices
Oxford physiologist Denis Noble reveals why your genes are not the blueprint for life, why evolution itself works nothing like the selfish gene made us believe, and why the failed promise to cure disease by reading our DNA points to a completely different understanding of health and aging!Denis Noble built the first working mathematical model of the heart in 1960 and is one of the founding figures of systems biology. He is a professor at Oxford with a career spent studying how living systems work, and he now argues that the genome is a database the living cell draws on, not the program running the show.He explains:◼️Why the Human Genome Project never delivered the cures we were promised◼️Why your DNA cannot actually predict most disease◼️The CD analogy: why studying genes tells you nothing about the music of life◼️His long-running clash with Richard Dawkins and the selfish gene◼️Why purpose and intelligence run all the way down, from your immune system to a predator hunting its preyEpisode Show Notes: https://livelongerworld.com/p/denisnobleTIMESTAMPS:00:00 The Selfish Gene Is Just Not Correct00:21 What Are Functional Networks, Really?02:09 Genes Build the Muscles, But Don't Move Them09:42 Your Genes Are a CD, Not the CD Player12:11 Can Your DNA Predict Your Disease? 14:23 If Not Genes, How Do We Find Cures?18:18 Then Does Gene Therapy Even Work?21:32 Why Scientists Can't Let the Paradigm Go24:08 What Darwin and Lamarck Actually Said31:42 Do Animals Choose? Darwin Thought So38:07 The Finite Monkeys Problem With Evolution45:15 Inheritance Without Changing Your DNA49:31 How Do You Actually Reproduce Denis Noble?50:49 Is the Selfish Gene Right From Evolution's View?54:45 Answering Jerry Coyne: Isn't DNA the Recipe?59:51 Who Wrote the Genetic Code?1:08:22 The Problem of Form: You Can't Get It From Genes1:12:01 The Mitochondria Accident That Made Complex Life1:13:05 Why Big Life Needs a Heart1:17:54 Why Mars Is a Pipe Dream1:18:45 Mike Levin and the Alignment of the Body1:21:29 What Does Denis Disagree With Mike Levin On1:24:59 The Biggest Taboo: Purpose in Biology1:27:35 Is Consciousness Just Expensive Energy?1:28:55 What Your Immune System Knows1:42:01 How Birds at Altitude Prove the Point1:44:29 Final Thoughts: Life Is More Interesting Than You ThinkDENIS NOBLE:Website: https://www.denisnoble.com/Books: https://www.denisnoble.com/buy/AASTHA, LIVE LONGER WORLD:Newsletter: https://livelongerworld.com/X: https://x.com/aasthajsInstagram: https://www.instagram.com/aasthajs/My health stack: https://www.healthstacked.com/aasthajsFull list of health products I use: https://www.healthstacked.com/aasthajsCAMERON, RICCI FLOW NUTRITION:Newsletter: https://ricciflow.substack.com/X: https://x.com/ricciflowhealthInstagram: https://www.instagram.com/ricciflownutrition/PREVIOUS PODCAST WITH DENIS NOBLE & MICHAEL LEVIN on Biology's Functional Networks, NOT Genes, are key for Longevity: https://www.youtube.com/watch?v=0_Ak-1rbbWg&t=3823s
0:00 – Cold Open / Welcome John and Jeff kick off the show, presented by FanDuel. Introduce guest Dr. Fredric Abramson — “smartest guy in any room… except maybe this one.” 2:00 – Abramson's Background & Injury Story Former athlete, tried out for the Pittsburgh Pirates. Broke his ankle at Michigan… then played his best golf round ever with a cast. Jeff explains why the locked‑up left leg actually improved his swing. 6:00 – The Origin of the DNA Injury Test Meeting with Philip Morris CEO: “Americans want to die healthy.” Abramson decides genetics should help people live better, not just diagnose disease. Human Genome Project inspires practical injury‑prediction research. 10:00 – How the Test Works Simple cheek swab — no blood, kid‑friendly, mail‑anywhere. Uses Illumina testing (same as 23andMe). Identifies genetic markers linked to injury susceptibility. Example: 8 known markers for concussion risk. 15:00 – Break / GhostBed Ad John explains why GhostBed keeps you cool and pain‑free. Promo code: golfguys. 17:00 – FanDuel Segment College sports talk: Indiana football hype, Michigan rivalry jokes. John threatens to ban Ohio State grads from the show. 20:00 – Injury Prediction for Golfers Back injuries most common in younger, high‑speed players. Older golfers deal with accumulated life injuries. DNA could help adjust swing load, warm‑ups, and training. 23:00 – Precision Nutrition Abramson holds the first patent in precision nutrition. Matching diet to DNA to improve recovery and reduce injury risk. 25:00 – Future Tech: AI Swing Analysis Planned mobile app: Upload swing video AI analyzes injury risk 3D body mapping Nutrition + genetics + mechanics combined 28:00 – John's Knee & Thursday Tee Time John asks if the test can help him by Thursday. Abramson: “Not yet — still a startup.” 30:00 – COVID Humor & Teaching Background Abramson lost his sense of smell after COVID. Corona beer joke. More banter about sports longevity and golf as a lifelong game. 33:00 – Closing Thoughts Golfers could play longer, safer, and smarter with DNA‑based injury prediction. Jeff imagines entire institutes jumping on this tech. Wrap‑up and tease future conversations. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Recorded at the Battle of Ideas festival 2025 on Sunday 19 October at Church House, Westminster. ORIGINAL INTRODUCTION The past 20 years have seen astonishing advances in science, technology and medicine. Building upon the completion of the Human Genome Project at the turn of the century, scientists have developed ever more powerful ways to sequence and study DNA, enabling us to better understand genetic diseases and develop pioneering treatments. Now, AI tools such as the AlphaFold program developed by Google DeepMind are also providing unprecedented understanding of the human proteome – the complete set of proteins made from instructions in our DNA. As well as acquiring powerful ways to study DNA, we have also acquired powerful ways to change it. CRISPR genome editing, which enables us to make precise changes to the DNA of humans and other organisms, is now widely used in laboratories across the world and has been used in life-saving treatments for devastating diseases. Meanwhile, stem-cell research has advanced to the point where it is now possible to create structures resembling early human embryos entirely from stem cells, instead of having to begin by fertilising an egg cell with a sperm cell. There is even speculation about one day being able to bypass pregnancy altogether. Some are thrilled about the new possibilities opened up by these developments, while others worry about human life being mechanised in ways that seem distasteful. Genetics, genomics, neuroscience and psychology can be (mis)used to seek to reduce human beings to brain circuits and physiological mechanisms, which can then be managed via modification, drugs or nudge-based policy. Who gets to decide what counts as progress, and who gets a say in how science is governed? What happens when the (in)famous Silicon Valley dictum ‘Move fast and break things' meets biology? What can be learned from incidents such as the He Jiankui scandal of 2018, in which a Chinese scientist who worked on human embryos in secret breached scientific and ethical standards, resulting in the birth of three children with edited genomes? How can oversight and rules be imposed, when the science is so complex and fast-moving, and when the world is made up of diverse (and in some cases warring) nation states? Over the past two decades, Sandy Starr of the Progress Educational Trust and Dr Stuart Derbyshire of the National University of Singapore have been involved in numerous national and international deliberations on science, ethics, policy and law in these areas. At this breakfast banter, they will compare their experiences, exchange insights and invite questions. DISCUSSANTS Dr Stuart Derbyshire associate professor, deputy head of psychology, National University of Singapore Sandy Starr deputy director, Progress Educational Trust; author, AI: Separating Man from Machine
In this episode of Lab Rats to Unicorns, John Flavin sits down with Luke Timmerman, founder of the Timmerman Report and one of biotechnology's most respected journalists and storytellers. For more than 25 years, Luke has chronicled the scientists, entrepreneurs, investors, and companies shaping the industry, giving him a unique perspective on how scientific discoveries become breakthrough medicines and how biotechnology has evolved over time. Luke reflects on his unlikely path into biotech, from growing up on a farm in Wisconsin and studying journalism at the University of Wisconsin–Madison to landing at The Seattle Times just as the Human Genome Project and Seattle's biotech ecosystem were gaining momentum. He shares lessons from covering the industry through decades of scientific breakthroughs and business cycles, writing his biography of genomics pioneer Leroy Hood, and ultimately taking an entrepreneurial leap of his own by launching the independent Timmerman Report. Throughout the conversation, Luke discusses why people, resilience, and continuous learning are at the heart of biotech innovation, as well as why he believes the industry is experiencing a golden period of scientific progress. He also shares the story behind the Timmerman Traverse, which grew from his passion for mountaineering into a philanthropic movement that has raised more than $15 million for cancer research, sickle cell disease, and other causes. Luke closes with his perspective on the importance of independent journalism, strong innovation ecosystems, and staying curious throughout a career.
The return of "What About?" Wednesdays! Text us your questions for apologist and pastor Robby Lashua!Sherman Mohler discovered a dinosaur.Well, technically, he was part of the team that unearthed, cataloged, researched, and ultimately named Ornatops incantatus, a type of duck-billed dinosaur that roamed northern New Mexico approximately 80 million years ago.By the way, Sherman discovered this dinosaur not too far from where he goes to church while he's on fossil expeditions.Wait. Church? Fossils? 80 million years? Is it possible to include all of these things in the same episode of Kingdom Culture Conversations?That is the reason that Sherman Mohler, a recognized and accomplished paleontologist, who serves as the president of the Southwest Paleontological Society, accepted the invitation to be our guest for what will be two days of very intriguing conversation. Plainly said, Sherman wants our students and listeners to know that you can follow Christ, believe your Bible, and hold to an understanding that the world is billions of years old. Further, he's inviting us to do the work -- read the research, study God's Word, examine the evidence -- and, decide for yourself, recognizing that your security in Christ and position in your Christian faith are not at risk.To learn more about the Southwest Paleontological Society, please follow this link.The SPS is part of the Arizona Museum of Natural History. To learn more about AZMNH, please click here.Ready to take Sherman Mohler up on his challenge? BioLogos.org is a Christian nonprofit organization founded by geneticist Francis Collins, best known for leading the Human Genome Project. The organization seeks to promote what it describes as the harmony between Christian faith and modern science, particularly in areas such as evolution, genetics, cosmology, and the age of the earth. BioLogos generally advocates for “evolutionary creation,” the view that God used evolutionary processes in creation. "Kingdom Culture Conversations" is a podcast created by Northwest Christian School in Phoenix, Arizona.For more information on Northwest Christian School, visit: https://www.ncsaz.org/To reach out to Geoff Brown, please email gbrown@ncsaz.org or you can reach him by cell phone: (623)225-5573.
In this episode of AI For Pharma Growth, Dr Andree Bates speaks with Bret Bostwick from Breyer Capital about the rare path from genetics, clinical medicine and drug development into venture capital, and what that perspective reveals about the future of healthcare innovation.Bret shares how the release of the Human Genome Project first pulled him into genetics, and how clinical work with patients made the science deeply practical. As a medical geneticist, he saw families finally receive a diagnosis, but often without a treatment option. That experience led him towards programmable therapeutics, RNA-based medicines and the translational work required to move from biological insight into human trials.The conversation explores what makes a therapeutic company investable beyond the science alone. Bret explains why breakthroughs often fail not just because of technical risk, but because the right people, culture, operating experience and business model are not around the table. For him, one of the first questions is not simply “does the science work?” but “what problem is this company really solving, and is this the most elegant solution?”They also discuss where AI is overhyped and underestimated in medicine. Bret is sceptical of claims that AI can compress a 12-year clinical development journey into two years, because biology still requires time to evaluate safety and efficacy. But he sees enormous potential in agentic AI across the full healthcare and pharma stack, from discovery and preclinical design to manufacturing, commercialisation and patient finding.The key message is that the future of healthcare will belong to people and companies that can bridge disciplines: genetics, computation, medicine, product development and investment. The biggest opportunities may sit at the intersections, where scientific insight, platform thinking and practical translation come together.Topics CoveredMoving from genetics and clinical medicine into venture capitalLessons from RNA therapeutics and translational medicineWhy target genetics matters in drug developmentWhat investors look for beyond the scienceWhy the right team and culture are criticalPlatform companies vs single-asset thinkingWhere AI can and cannot compress drug developmentAgentic AI across pharma and healthcare workflowsFounder mistakes when pitching healthcare investorsEularis helps pharma and biotech leaders turn AI activity into board-defensible strategy and measurable commercial outcomes.If your organisation has plenty of AI in motion but very little that moves the commercial needle in a way the board can see, start with our 10-Day AI Diagnostic Sprint. It's a focused diagnostic that surfaces what's actually broken and what's blocking results, before you invest in a larger strategy effort.The Sprint diagnoses the problem. The AI Strategic Blueprint that follows is where we build the board-defensible strategy and plan.Details at eularis.com.AI platforms and tools solve specific problems. Strategy makes sure you're solving the right ones, in the right order. If you want help mapping priorities as you evaluate what to roll out next, send me a LinkedIn DM starting with ‘PRIORITIES' and two lines: what's already in flight, and the decision you're trying to make next.About the PodcastAI For Pharma Growth is the podcast from pioneering Pharma Artificial Intelligence entrepreneur Dr Andree Bates, created to help pharma, biotech and healthcare organisations understand how AI-based technologies can save time, grow brands, and improve company results.This show blends deep sector experience with practical conversations that demystify AI for biopharma leaders, from start-up biotech right through to Big Pharma. Each episode features experts building AI-powered tools that are driving real-world results across discovery, R&D, clinical trials, medical affairs, market access, regulatory, insights, sales, marketing, and more.Dr. Andree Bates LinkedIn | Facebook | X
The return of "What About?" Wednesdays! Text us your questions for apologist and pastor Robby Lashua!Sherman Mohler discovered a dinosaur.Well, technically, he was part of the team that unearthed, cataloged, researched, and ultimately named Ornatops incantatus, a type of duck-billed dinosaur that roamed northern New Mexico approximately 80 million years ago.By the way, Sherman discovered this dinosaur not too far from where he goes to church while he's on fossil expeditions.Wait. Church? Fossils? 80 million years? Is it possible to include all of these things in the same episode of Kingdom Culture Conversations?That is the reason that Sherman Mohler, a recognized and accomplished paleontologist, who serves as the president of the Southwest Paleontological Society, accepted the invitation to be our guest for what will be two days of very intriguing conversation. Plainly said, Sherman wants our students and listeners to know that you can follow Christ, believe your Bible, and hold to an understanding that the world is billions of years old. Further, he's inviting us to do the work -- read the research, study God's Word, examine the evidence -- and, decide for yourself, recognizing that your security in Christ and position in your Christian faith are not at risk.To learn more about the Southwest Paleontological Society, please follow this link.To learn more about the Arizona Museum of Natural History, please click here.Ready to take Sherman Mohler up on his challenge? BioLogos.org is a Christian nonprofit organization founded by geneticist Francis Collins, best known for leading the Human Genome Project. The organization seeks to promote what it describes as the harmony between Christian faith and modern science, particularly in areas such as evolution, genetics, cosmology, and the age of the earth. BioLogos generally advocates for “evolutionary creation,” the view that God used evolutionary processes in creation. "Kingdom Culture Conversations" is a podcast created by Northwest Christian School in Phoenix, Arizona.For more information on Northwest Christian School, visit: https://www.ncsaz.org/To reach out to Geoff Brown, please email gbrown@ncsaz.org or you can reach him by cell phone: (623)225-5573.
Why did a monk in a Moravian monastery spend eight years counting 30,000 pea plants — and how did the number three to one unlock the secret of heredity that Charles Darwin couldn't solve? Why did Gregor Mendel publish one of the greatest scientific discoveries of the nineteenth century to almost complete silence, only for his paper to be rediscovered thirty-four years later by three scientists who had all independently reached the same conclusion? And how did the statistician who accused him of fraud turn out to have made the statistical error himself?Join John and Patrick as they tell the story of Czechia and the pea — the monastery garden, the number that changed biology, and the 145-year arc from Mendel's first cross-pollination to the Human Genome Project...----------In Sponsorship with J&K Fresh.The customs broker who is your fruit and veggies' personal bodyguard. Learn more here!-----------Join the History of Fresh Produce Club for ad-free listening, bonus episodes, book discounts and access to an exclusive chatroom community.Support us!Share this episode with your friendsGive a 5-star ratingWrite a review-----------Subscribe to our biweekly newsletter here for extra stories related to recent episodes, book recommendations, a sneak peek of upcoming episodes and more.-----------Instagram, TikTok, Threads:@historyoffreshproduceEmail: historyoffreshproduce@gmail.com
As we continue our summer programming around a specific theme in the headlines, this week we're focusing on the subject of truth in media with previous Bulletin guests Chris Stirewalt, Francis Haugen, Renee DiResta, and Francis Collins. This episode of The Bulletin weaves together three distinct conversations exploring the death of local reporting, the rise of algorithmic echo chambers, and a practical blueprint for how Christians can navigate the news with wisdom and discernment. GO DEEPER WITH THE BULLETIN: Join the conversation at our Substack. Find us on YouTube. Rate and review the show in your podcast app of choice. ABOUT THE GUESTS: Chris Stirewalt is a senior fellow at the American Enterprise Institute where he focuses on American politics, voting trends, public opinion, and the media. He is concurrently a contributing editor and weekly columnist for The Dispatch, and the host of The Hill Sunday with Chris Stirewalt on NewsNation. A well-known political commentator, Mr. Stirewalt is the author of Broken News: Why the Media Rage Machine Divides America and How to Fight Back. Francis Collins, MD, PhD, served as director of the National Institutes of Health (NIH) under presidents Obama, Trump, and Biden. Prior to that, he led the Human Genome Project at NIH, coordinating a consortium of laboratories to produce the first ever complete sequence of human DNA in 2003. Collins's research has led to landmark discoveries of disease genes and helped pioneer a multitude of therapies for many diseases. Renee DiResta is a professor, writer and former research manager at Stanford Internet Observatory. DiResta has written about pseudoscience, conspiracy theories, terrorism, and state-sponsored information warfare. Frances Haugen is an American data scientist and product manager who became a prominent whistleblower in 2021 after disclosing thousands of internal Facebook documents to the SEC and The Wall Street Journal. She highlighted that Facebook prioritized profit over safety, fostering hate and misinformation. ABOUT THE BULLETIN: The Bulletin is a twice-weekly news analysis podcast from Christianity Today, with editor-at-large Russell Moore. Each episode offers commentary on current events and headlining news with a roundtable of premier guests, and shares a Christian perspective on issues that are shaping our world The Bulletin listeners get 25% off CT. Go to https://orderct.com/THEBULLETIN to learn more. “The Bulletin” is a production of Christianity Today Host: Leslie Thompson Associate Producers: Alexa Burke and Crystal Dady Editing and Mix: Kevin Morris Graphic Design: Rick Szuecs Music: Dan Phelps Executive Producer: Erik Petrik Senior Producer: Matt Stevens Learn more about your ad choices. Visit podcastchoices.com/adchoices
It's common knowledge that many diseases and conditions have some kind of genetic link. But that wasn't always the case. In 1990, long before the Human Genome Project tied so many health issues to differences in genetics, researchers identified a gene called BRCA1. It was the first gene linked to a hereditary form of any common cancer. People with certain variants of BRCA1 stood a higher risk of developing breast and ovarian cancer than those without those mutations. Geneticist Mary-Claire King and her lab were the first to identify that gene. She joined Host Flora Lichtman in September 2025 to talk about her background, her research, and her approach to science. Guest: Dr. Mary-Claire King is an American Cancer Society Professor in the departments of Genome Sciences and Medicine at the University of Washington in Seattle. Other episodes you may enjoy: A Nagasaki Survivor And Physician Recounts His Life's Work I Was Considered A Nobody Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-4-SCIFRI Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this episode, Peter explores the complex and often misunderstood world of genetic testing, building a practical framework for understanding what these tests can and cannot actually tell us about health and disease. He explains why some genetic findings can be genuinely life-changing while many others offer information that is far more probabilistic than deterministic, and why directly measuring the phenotype is often more valuable than inferring risk from DNA alone. Peter examines where genetics can provide meaningful insight across the major disease categories and where its predictive power is far more limited than many people assume. He also discusses how to think critically about different types of genetic tests, how to interpret results in the proper context, and how to avoid the common trap of accumulating more genetic information without gaining greater clarity or actionable insight. We discuss: Genetic testing: understanding what it can reveal, where it falls short, and how to think about its clinical value [1:45]; The Human Genome Project: why decoding DNA did not immediately unlock the mysteries of disease [4:15]; The limitations of genetic testing: probabilistic risk, interpretive uncertainty, and the importance of phenotype [9:30]; Questions to ask when considering genetic testing [15:45]; Genetic testing in cardiovascular and metabolic disease: when genotype adds value beyond phenotype [17:00]; Genetic testing for inherited cardiac conditions: identifying hidden risk beyond routine screening [21:45]; Genetic testing for cancer risk: inherited syndromes, clinical utility, and the limits of consumer testing [24:00]; Genetic testing for neurodegenerative disease: risk prediction, planning, and the challenge of limited actionability [28:45]; Functional medicine genetic testing: the gap between biological plausibility and clinical evidence, and the supplement protocols that aren't supported by evidence [32:45]; Pharmacogenetics: using genetic testing to guide medication selection and safety [38:45]; A framework for evaluating genetic tests according to effect size and clinical actionability [41:45]; The major types of genetic tests, and how each should be matched to the clinical question being asked [43:30]; Interpreting genetic test results: choosing the right testing laboratory and understanding what the findings actually mean [49:45]; Framework summary: why genetic testing is most valuable when it is guided by a clear question, matched with the appropriate test, and capable of meaningfully influencing decisions [56:45]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube
Rewind to 14 – 20 May 2006: it's science breakthroughs, shiny new tech and tabloid culture at its absolute messiest.
Jared Dashevsky, MD (Healthcare Huddle) and Ala Alenazi, PhD (Kinnevik) join Mustafa to discuss:The rise of the AI Broker (a middleman that's about to emerge)Palantir's £330M NHS break clauseOpenAI as pharma. We also discuss why drug discovery needs a "Human Genome Project 2.0"
The Kremlin planned to provide Iran with unjammable drones, plus training in how to use them, according to leaked documents seen exclusively by The Economist. Meanwhile there are nearly 20,000 merchant seamen stranded in the Gulf. And a tribute to Craig Venter, dark horse of the Human Genome Project.Watch extended clips from Economist Insider here.Guests and host:Shashank Joshi, defence editorJoshua Spencer, Asia news editorGeoffrey Carr, senior editor, science and technologyRosie Blau, co-host of “The Intelligence”Jason Palmer, co-host of “The Intelligence”Topics covered: Iran war, Russia, dronesCommercial shippingCraig VenterGet a world of insights by subscribing to Economist Podcasts+. For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account. Hosted on Acast. See acast.com/privacy for more information.
The Kremlin planned to provide Iran with unjammable drones, plus training in how to use them, according to leaked documents seen exclusively by The Economist. Meanwhile there are nearly 20,000 merchant seamen stranded in the Gulf. And a tribute to Craig Venter, dark horse of the Human Genome Project.Watch extended clips from Economist Insider here.Guests and host:Shashank Joshi, defence editorJoshua Spencer, Asia news editorGeoffrey Carr, senior editor, science and technologyRosie Blau, co-host of “The Intelligence”Jason Palmer, co-host of “The Intelligence”Topics covered: Iran war, Russia, dronesCommercial shippingCraig VenterGet a world of insights by subscribing to Economist Podcasts+. For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account. Hosted on Acast. See acast.com/privacy for more information.
1) History-making entrepreneurial scientist CRAIG VENTER, died last week at the age of 79. The New York Times obituary leads with these words, “A risk-taking outsider, he brought speed, competition, and controversy to one of science's biggest races.” In 2000, his team published the first sequence of the human genome – earlier and for far less money than the government-sponsored Human Genome Project. Here's our 2008 conversation, on the release of his memoir, A LIFE DECODED: MY GENOME: MY LIFE. Learn more at jcvi.org 2) In the second half, my 2008 conversation with MacArthur Award winning evolutionary biologist STUART KAUFFMAN about his book, REINVENTING THE SACRED: A NEW VIEW OF SCIENCE, REASON, AND RELIGION. The two of us get excited as we work our way toward his notion that the ceaseless creativity of the universe may be the best way yet to think about God. Learn more at stuartkauffman.com
Craig Venter recently passed away at the age of 79 from complications following a cancer diagnosis. He was well known in both science and industry and was an integral part of sequencing the human genome in the late 90s, competing with the government organized Human Genome Project. Through his career, he made many other important contributions in microbiology, with the “minimal cell”, in synthetic biology, and in personalized medicine. GEN editors share anecdotes of their experiences with him, reflect on the impact that his work has had on various fields in biology, in biotech, and in how the world has responded to the disruptions caused by Venter. Join GEN editors Corinna Singleman, PhD, John Sterling, Kevin Davies, PhD, and Uduak Thomas for a discussion of the latest biotech and biopharma news. Listed below are links to the GEN stories referenced in this episode of Touching Base: Genomics Pioneer and Life Sciences Entrepreneur J. Craig Venter Dies at 79 GEN, April 30, 2026 J. Craig Venter Describes a Human Genomics Revolution Still In ProgressBy J. Craig Venter, PhD, GEN, June 13, 2025 Lessons from the Minimal CellBy Hana El-Samad, PhD, GEN, August 21, 2023 From Sequencing to Sailing: Three Decades of Adventure with Craig VenterBy Fay Lin, PhD, GEN, March 8, 2023 “Cracking the Genome” By Kevin Davies, PhDTouching Base Podcast Hosted by Corinna Singleman, PhD Behind the Breakthroughs Hosted by Jonathan D. Grinstein, PhD Hosted on Acast. See acast.com/privacy for more information.
May we resolve to live not by lies, political correctness, wokeness, or ‘repressive tolerance‘ by any name. May we live by the Truth alone, and may God have mercy on us. Political correctness is communist propaganda writ small. In my study of communist societies, I came to the conclusion that the purpose of communist propaganda was not to persuade or convince, nor to inform, but to humiliate; and therefore, the less it corresponded to reality the better. When people are forced to remain silent when they are being told the most obvious lies, or even worse when they are forced to repeat the lies themselves, they lose once and for all their sense of probity. To assent to obvious lies is to co-operate with evil, and in some small way to become evil oneself. One’s standing to resist anything is thus eroded, and even destroyed. A society of emasculated liars is easy to control. I think if you examine political correctness, it has the same effect and is intended to. — Theodore Dalrymple (Anthony Daniels) Frontpage Magazine interview (August 31, 2005) But what saith it? The word is nigh thee, [even] in thy mouth, and in thy heart: that is, the word of faith, which we preach; That if thou shalt confess with thy mouth the Lord Jesus, and shalt believe in thine heart that God hath raised him from the dead, thou shalt be saved. For with the heart man believeth unto righteousness; and with the mouth confession is made unto salvation. For the scripture saith, Whosoever believeth on him shall not be ashamed. For there is no difference between the Jew and the Greek: for the same Lord over all is rich unto all that call upon him. For whosoever shall call upon the name of the Lord shall be saved. — Romans 10:8-13 KJV Jesus saith unto him, I am the way, the truth, and the life: no man cometh unto the Father, but by me. — John 14:6 KJV Links Videos / Clips [x] = Played Triggered! Featuring Dave Chappelle- He Rapes But He Saves! [x] 0:47--2:23 The Problem With Feminising Society – Helen Andrews [x] 1:00--4:06 Headlines [x] = Mentioned / Discussed Featured [x] Google, Microsoft, Meta All Tracking You Even When You Opt Out, According to an Independent Audit High-Profile Deviance [x] Democrat [Kevin Cichowski] who wants to be Florida’s next governor is filmed being arrested after allegedly beating up two elderly people with a cane and phone | Daily Mail Online [x] Tony Gonzales says he will resign from House – POLITICO Eric Swalwell and curious coincidences of timing [x] Swalwell says he plans to resign from Congress amid sexual assault allegations – ABC News [x] Exclusive | Bleary-eyed Eric Swalwell wears a robe, parties with ‘yacht girls' during ‘hush hush' St. Tropez blow-out, wild video shows Double Standard…? [x] Trump, 79, Thirsts Over Woman in Front of Teenage Grandson, Donald Trump III The woman is Nina Coates, a golf content creator from Taiwan. Coates, who lives in Miami, responded to the president's affections on social media. “Yes I'm married,” she wrote alongside a laughing face emoji. A HuffPost analysis released on March 28 found that Trump's golf excursions have cost the taxpayer at least $101.2 million in travel and security expenses since his return to office in January last year. All of Trump's wives have been younger than him. He married his current wife, first lady Melania Trump, in 2005. She is 55, 24 years younger than her husband. Before Melania, there was Marla Maples, who is 62. His first wife, Ivanka Trump,[sic] died at 73 in July 2022. The Rest [x] = Mentioned / Discussed Live Not By Lies Theodore Dalrymple – Wikipedia Anthony Daniels (psychiatrist) – Wikiquote [x] FrontPage Magazine – Our Culture, What's Left Of It [x] THE MYTHOLOGY OF AMERICAN DEMOCRACY – A Lecture by Carroll Quigley Ph.D. [x] Bandwagon effect – Wikipedia [x] Mob rule – Wikipedia The Deviance of Trump [x] Donald Trump sexual misconduct allegations – Wikipedia Marla marla maples donald trump rape at DuckDuckGo [x] Scandalous Details About Donald Trump And Marla Maples’ Marriage [x] Trump believed rape accuser E. Jean Carroll was wife in photo [x] ‘It’s Marla’: Donald Trump confuses rape accuser with ex-wife, trial told | US News | Sky News [x] Leaked Donald Trump tapes dredges up 1989 spousal rape accusation Ivana ivana trump, donald trump rape at DuckDuckGo [x] Donald Trump’s ex-wife’s claim he ‘raped’ her resurfaces in new documentary | The Independent | The Independent [x] Did ivana trump say Donald trump raped her Ivanka ivanka trump at DuckDuckGo [x] Ivanka Trump Believes Alleged Victims of Sexual Misconduct—Unless They're Accusing Her Father Donald Trump’s comments about daughter raise eyebrows – CNN – YouTube Donald Trump: “If Ivanka weren’t my daughter, perhaps I’d be dating her.” – YouTube Ivanka Trump: All the times Donald Trump was inappropriate with his daughter | indy100 Donald Trump thinks Ivanka is ‘hot’ and would ‘date her if she wasn’t my daughter’ – The Mirror Donald Trump’s unsettling record of comments about his daughter Ivanka | The Independent | The Independent Behavioral Sink [x] Behavioral sink – Wikipedia [x] Population Density and Social Pathology: When a population of laboratory rats is allowed to increase in a confined space, the rats develop acutely abnormal patterns of behavior that can even lead to the extinction of the population – 1962-calhoun.pdf Beirut on the Charles GQ Article Draws Law Students’ Ire | News | The Harvard Crimson [x] Beirut on the Charles: At faction-ridden Harvard Law School, the only natural impulse that remains above suspicion is ambition itself (Feb, 1993) by John Sedgwick – GQ_BeirutOnTheCharlesFull.pdf Degenerate “Cultural Bolshevism” Herbert Marcuse – Wikipedia Joseph Goebbels – Wikipedia Cultural Marxism conspiracy theory – Wikipedia Marcusean ‘Repressive Tolerance’ at Work Sweet Cakes by Melissa – Cases – First Liberty Klein v. Oregon Bureau of Labor and Industries – Wikipedia [x] Masterpiece Cakeshop v. Colorado Civil Rights Commission – Wikipedia On This Day Events April 2026 Calendar of Public Holidays | Office Holidays Holidays and Observances in the United States in 2026 What day is it today? Important events every day ad-free | United States OTD Worldwide Public Holidays Tuesday April 14th 2026 | Office Holidays On This Day – What Happened on April 14 Today in History: April 14, Abraham Lincoln fatally shot at Ford’s Theatre | AP News What Happened on April 14 – On This Day What Happened on April 14 | HISTORY April 14 – Wikipedia What Happened On April 14 In History? 14 | April | 2020 | Executed Today Holidays Dolphin Day (US) Ex-Spouse Day (US) Gardening Day (US) Library Workers Day (US) Pan American Day (US) Pecan Day (US) Reach As High As You Can Day (US) That Sucks Day (US) Yom HaShoah Day (Jewish commemoration) ‘Six million Jews in WWII’ is a grossly inflated number, which is a marginalizing disservice to victims everywhere. That’s not ‘Holocaust denial’. It’s not denying the reality of genocidal tragedy – on the contrary, it affirms the tragedy(s) everywhere. This group does not have a monopoly on tragedy, as R.J. Rummel proved in DEATH BY GOVERNMENT: GENOCIDE AND MASS MURDER in which he coined the term ‘democide’. Despite relentless attempts to denigrate him (wonder why?) David Irving‘s work is instructive, and he is an unimpeachable witness. Why would a man be banned from entire countries simply for his ideas…? There’s also Edwin Black’s IBM and the Holocaust and the subject of what it more broadly represents (i.e., fascism)… There’s also the controversy of the term ‘holocaust’; “A burnt sacrifice; an offering, the whole of which was consumed by fire, among the Jews and some pagan nations”…?? World Quantum Day (Intl) Historical Events 2015 – Archaeologists announce they have found 3.3 million-year-old stone tools at Lomekwi in Kenya, the oldest ever discovered and predating the earliest humans 2003 – The Human Genome Project is completed: The project dedicated to mapping the genes of the human genome was started in October 1990. 2002 – 66th US Masters Tournament: Tiger Woods becomes the third player to claim back-to-back Masters, three strokes ahead of Retief Goosen of South Africa 2000 – Metallica files a lawsuit against the peer-to-peer sharing platform Napster, accelerating a movement against file-sharing programs 1996 – Greg Norman blows six-shot Masters lead in epic collapse: Third-round leader Greg Norman loses a six-shot lead in the final round of the Masters golf tournament and finishes second—one of the worst collapses in sports history. Nick Faldo wins the green jacket, finishing five strokes ahead of Norman. “I played like a bunch of [expletive],” the Australian tells reporters afterward.… read more 1994 – Musician Billy Joel & supermodel Christie Brinkley announce plans to divorce 1994 – In a friendly fire incident during Operation Provide Comfort in northern Iraq, two U.S. Air Force aircraft mistakenly shoot-down two U.S. Army helicopters, killing 26 people. 1991 – The Republic of Georgia introduces the post of President following its declaration of independence from the Soviet Union. 1988 – The USS Samuel B. Roberts strikes a mine in the Persian Gulf during Operation Earnest Will. 1988 – The Soviet Union agrees to withdraw from Afghanistan: In a United Nations ceremony in Geneva, Switzerland, the Soviet Union signs an agreement pledging to withdraw its troops from Afghanistan. Soviet troops had invaded the country in 1979 to support the communist rulers. They were defeated primarily by the Mujahideen, who were groups of militant Islamists sponsored by the CIA.123 1986 – U.S. bombs terrorist and military targets in Libya: In retaliation for the April 5 bombing in West Berlin that killed two U.S. servicemen, U.S. president Ronald Reagan orders major bombing raids against Libya, killing 60 people. The raid, which began shortly before 7 p.m. EST (2 a.m., April 15 in Libya), involved more than 100 U.S. Air Force and Navy aircraft, and was over within an… read more 1986 – The heaviest hailstones ever recorded hit Bangladesh: The lumps of ice weighed about 1 kg (2.2 lb). At total of 92 people reportedly died as a result. 1969 – Katharine Hepburn and Barbra Streisand tie for Best Actress Oscar: During the first internationally televised Oscars ceremony, Ingrid Bergman exclaims “It's a tie!” upon opening the Best Actress envelope—the first tie in a major acting category in three decades. The award went to both Katharine Hepburn, for her turn as Eleanor of Aquitaine in The Lion in Winter, and Barbra Streisand,… read more 1960 – Montreal Canadiens win fifth consecutive Stanley Cup: The Montreal Canadiens defeat the Toronto Maple Leafs to win the Stanley Cup for a record fifth year in a row. The Canadiens reached the Stanley Cup Finals after sweeping the Chicago Blackhawks in four games, while the Maple Leafs defeated the Detroit Red Wings, four games to two. The championship… read more 1956 – In Chicago, Illinois, videotape is first demonstrated. 1944 – Explosion on cargo ship rocks Bombay, India: The cargo ship Fort Stikine explodes in a berth in the docks of Bombay, India (now known as Mumbai), killing 1,300 people and injuring another 3,000. As it occurred during World War II, some initially claimed that the massive explosion was caused by Japanese sabotage; in fact, it was a tragic… read more 1939 – The Grapes of Wrath, by American author John Steinbeck is first published by the Viking Press. 1935 – “Black Sunday” Dust Bowl storm strikes: In what came to be known as “Black Sunday,” one of the most devastating storms of the 1930s Dust Bowl era sweeps across the region. High winds kicked up clouds of millions of tons of dirt and dust so dense and dark that some eyewitnesses believed the world was coming to… read more Was it ‘accidentally’ engineered…?678910 1932 – Loretta Lynn is born: Loretta Lynn, a singer who greatly expanded the opportunities for women in the male-dominated world of country-western music, is born in Butcher Hollow, Kentucky. Unlike some country-western stars that sang about a rural working class life but lived an urban middle class existence, Loretta Lynn's country roots were unquestionably authentic. Born Loretta… read more 1931 – First edition of the Highway Code published in Great Britain. 1927 – The first Volvo car premieres in Gothenburg, Sweden. 1918 – American pilots engage in first dogfight over the western front: Six days after being assigned for the first time to the western front, two American pilots from the U.S. First Aero Squadron engage in America's first aerial dogfight with enemy aircraft. In a battle fought almost directly over the Allied Squadron Aerodome at Toul, France, U.S. fliers Douglas Campbell and Alan Winslow succeeded in shooting… read more 1912 – Doomed passenger liner RMS Titanic hits an iceberg in the North Atlantic: The subsequent sinking of the world’s largest ocean liner of the time resulted in more than 1500 deaths. It was one of the worst peacetime maritime disasters in history. Was there more to the story…? 1910 – Taft becomes first U.S. president to throw out first pitch at MLB game: Skull and Bonesman,11 President William Howard Taft becomes the first president to throw out the ceremonial first pitch at a Major League Baseball game. The historic toss on opening day is to star Walter Johnson, the Washington Senators' starting pitcher against the Philadelphia Athletics at National Park in the nation's capital.… read more 1909 – Armenian Genocide: A massacre is organized by Ottoman Empire against Armenian population of Cilicia. Muslims in the Ottoman Empire begin a massacre of Armenians in Adana. 1908 – Hauser Dam, a steel dam on the Missouri River in Montana, fails, sending a surge of water 25 to 30 feet (7.6 to 9.1 m) high downstream. 1906 – The first meeting of the Azusa Street Revival, which will launch Pentecostalism as a worldwide movement, is held in Los Angeles. 1894 – The first ever commercial motion picture house opens in New York City. It uses ten Kinetoscopes, devices for peep-show viewing of films. 1894 – First public showing of Thomas Edison’s Kinetoscope (moving pictures) 1890 – The Pan-American Union is founded by the First International Conference of American States in Washington, D.C. 1890 – Painter Pierre-Auguste Renoir (49) weds Aline Victorine Charigot 1881 – The Four Dead in Five Seconds Gunfight occurs in El Paso, Texas. 1880 – Philosopher John Muir (41) weds Louisa Strentzel 1865 – William H. Seward, the U.S. Secretary of State, and his family are attacked at home by Lewis Powell. 1865 – Ulysses S. Grant and his wife turn down an invitation to join President and Mrs. Lincoln at Ford's Theatre to see the comedic play Our American Cousin. In doing so, he deprives assassin John Wilkes Booth of a second target. 1865 – U.S. President Abraham Lincoln is shot: President Abraham Lincoln was shot and fatally wounded during a performance of the play Our American Cousin at Ford's Theatre in Washington; Lincoln was taken to a boarding house across the street and died the following morning at 7:22 am. The assassin, John Wilkes Booth, wanted to revive the Confederate cause, mere days after their surrender to the Union Army, bringing the American Civil War to an end. At least, that’s the official story…45 1846 – The Donner Party of pioneers departs Springfield, Illinois, for California, on what will become a year-long journey of hardship, cannibalism, and survival. 1828 – First Edition of Webster's American Dictionary of the English Language is printed: Noah Webster, a Yale-educated lawyer with an avid interest in language and education, publishes his American Dictionary of the English Language. Webster's dictionary was one of the first lexicons to include distinctly American words. The dictionary, which took him more than two decades to complete, introduced more than 10,000 “Americanisms.” [Because, defining terms is important! Who’s in charge; who decides…?]… read more 1775 – First American abolition society founded in Philadelphia: The Society for the Relief of Free Negroes Unlawfully Held in Bondage, the first American society dedicated to the cause of abolition, is founded in Philadelphia by Benjamin Franklin and Benjamin Rush. The society changes its name to the Pennsylvania Society for Promoting the Abolition of Slavery and the Relief of Free Negroes Unlawfully Held in Bondage… read more 70 – Siege of Jerusalem: Titus, son of emperor Vespasian, surrounds the Jewish capital, with four Roman legions. Births 1975 – Anderson Silva, Brazilian mixed martial artist and boxer (51) 1973 – Adrien Brody, Performer who became the youngest Best Actor Oscar winner playing a Holocaust survivor in The Pianist. (53) 1941 – Pete Rose, Baseball great nicknamed “Charlie Hustle” who topped Ty Cobb’s record for career hits. Banned from the sport in 1989 for gambling. (died 2024) 1932 – Loretta Lynn, Queen of country music who was born a coal miner’s daughter—which inspired her biggest hit and an Oscar-winning biopic. (died 2022) 1925 – Rod Steiger, American soldier and actor (died 2002) 1907 – François “Papa Doc” Duvalier, Haitian dictator (died 1971) 1889 – Arnold J. Toynbee, English historian and academic, key architect of the Third British Empire author of 12-volume A Study of History (Oxford University Press 1939). (died 1975) 1738 – William Cavendish-Bentinck, 3rd Duke of Portland, English politician, Prime Minister of the United Kingdom (died 1809) Deaths 2021 – Bernie Madoff, American mastermind of the world’s largest Ponzi scheme [except for the Federal Reserve!] (born 1938) 2015 – Percy Sledge, American singer (born 1940) 2013 – George Jackson, American singer-songwriter (born 1945) 2013 – Charlie Wilson, American politician (born 1943) 2007 – Don Ho, American singer and ukulele player (born 1930) 1995 – Burl Ives, American actor, folk singer, writer, and freemason (born 1909) 1943 – Yakov Dzhugashvili, Georgian-Russian lieutenant, eldest son of Joseph Stalin (born 1907) 1759 – George Frideric Handel, German-English organist and composer (born 1685) Footnotes Wikipedia Contributors. “Operation Cyclone.” Wikipedia, Wikimedia Foundation, 10 May 2019, en.wikipedia.org/wiki/Operation_Cyclone. Accessed 14 Apr. 2026. ↩ “How Jimmy Carter and I Started the Mujahideen.” CounterPunch.org, CounterPunch, 8 Nov. 2015, www.counterpunch.org/1998/01/15/how-jimmy-carter-and-i-started-the-mujahideen/. Accessed 14 Apr. 2026. ↩ Dixon, Norm. “How the CIA Created Osama Bin Laden.” Green Left, 18 Sept. 2001, www.greenleft.org.au/2001/465/analysis/how-cia-created-osama-bin-laden. Accessed 14 Apr. 2026. ↩ Perloff, James. Exploding the Official Myths of the Lincoln Assassination. 2024, www.amazon.com/dp/0966816064. Accessed 14 Apr. 2026. ↩ Perloff, James. “Announcing James Perloff's Latest Book.” Jamesperloff.net, 2026, jamesperloff.net/announcing-james-perloffs-latest-book/. Accessed 14 Apr. 2026. ↩ FDRLibrary. “FDR and the Dust Bowl.” YouTube, 20 June 2018, www.youtube.com/watch?v=LRAbOAim8U8. Accessed 14 Apr. 2026. ↩ Wikipedia Contributors. “Dust Bowl.” Wikipedia, Wikimedia Foundation, 27 Feb. 2019, en.wikipedia.org/wiki/Dust_Bowl. Accessed 14 Apr. 2026. ↩ Wikipedia Contributors. “Deforestation.” Wikipedia, Wikimedia Foundation, 15 Jan. 2019, en.wikipedia.org/wiki/Deforestation. Accessed 14 Apr. 2026. ↩ Wikipedia Contributors. “Desertification.” Wikipedia, Wikimedia Foundation, 25 May 2019, en.wikipedia.org/wiki/Desertification. Accessed 14 Apr. 2026. ↩ Snyder, Michael. “1930s Dust Bowl Conditions Are Returning to the Middle of the United States.” Substack.com, Michael Snyder's Substack, 8 Apr. 2025, michaeltsnyder.substack.com/p/1930s-dust-bowl-conditions-are-returning. Accessed 14 Apr. 2026. ↩ Best of Danny Jones. “The Man Who Was BORN into the Deep State Finally Speaks | Kris Millegan.” YouTube, 10 Apr. 2026, youtu.be/eM8eMtcNACw. Accessed 14 Apr. 2026. 7:00--34:00 Kris Millegan on; William Howard Taft, Alphonso Taft, William Huntington Russell, Phi Beta Kappa, Skull and Bones, the (family) history of the (modern) opium trade, and American football. ↩
Dr. Manish Patel, co-founder and CEO of Jiva.ai and Chair of the AI Subcommittee at the BIA, where he advises the UK Government on AI policy, data privacy and healthcare applications. With a PhD in Modelling of Complex Systems from UCL and nearly a decade building algorithmic trading systems in investment banking, Manish brings a rare depth of perspective to the most overhyped term in healthcare right now.In this episode, we cut through the noise on AI. Manish challenges the very language we use, explaining why most of what gets called "AI" is really machine learning, why large language models are fundamentally not intelligent and why that distinction has very real consequences when lives are on the line. We look at where AI genuinely adds value in healthcare, from radiology to NHS administrative workflows, and where it is being dangerously overhyped, including some very pointed thoughts on using consumer-grade LLMs to make clinical diagnoses.We also explore how clinicians should think about AI as an augmenter rather than a replacement, why the productivity gains are real and where Manish believes the biggest untapped opportunity in healthcare actually sits. He closes with a frank take on what impressive AI looks like in a real clinical environment versus a polished demo and why the world is heading toward a very small group of people who truly understand what is happening under the hood.Thanks for tuning in to Episode 99. Don't forget to subscribe and check the show notes to learn more about Manish's work at Jiva.ai and his advisory role shaping UK AI policy in healthcare.Timestamps[00:00:28] From the Human Genome Project to Machine Learning: Manish's Academic Origins [00:02:09] AI Has Been Around Since the 1950s: The History Most People Don't Know [00:04:09] Why Tacking "AI" onto Your Product Name Is a Problem [00:05:24] Where Healthcare AI Really Is: Step Three Not Step 100 [00:06:06] Why Using Grok for Medical Diagnosis IsDangerous [00:09:48] Should Clinicians Be Scared AI Will Take Their Jobs?[00:12:18] How to Actually Start Learning About AI: Where to Begin [00:14:01] Writing the Book on AI Agents in 2011 [00:18:04] The Biggest Untapped Opportunity: Administrative AI Not Diagnostic AI [00:20:40] What Real Clinical AI Success Looks Like vs a Polished DemoConnect with Manish- https://www.linkedin.com/in/manish-patel/Learn more about Jiva ai - https://jiva.ai/Get in touch with Karandeep Badwal - https://www.linkedin.com/in/karandeepbadwal/ Follow Karandeep on YouTube - https://www.youtube.com/@KarandeepBadwal
talk that scientific research - we are all equalModern science concludes that all human races are biologically equal, finding no genetic basis for racial superiority or inferiority. The Human Genome Project confirmed that humans are 99.9% identical at the DNA level, with more genetic variation within racial groups than between them. "Race" is recognized as a social construct rather than a biological reality
Eric Green is a genomic researcher whose work with the Human Genome Project on mapping and sequencing DNA has revolutionized the medical field. From sampling patients' DNA through blood tests to screen for diseases to identifying which medicine works best with your DNA, Green argues that genomic sequencing isn't just effective—it's economical.Learn more about our flagship conference happening this April at attend.ted.com/podcast Hosted on Acast. See acast.com/privacy for more information.
Mentor Sessions Ep. 054: Peter McCormack & Dr. Jack Kruse Fabian Society Exposed: History, Money, Power, & HealthWhat if a centuries-old Fabian Society plot is secretly reclaiming absolute control over UK politics, money, and power—tying into Bitcoin's decentralized revolution, Epstein's hidden genome obsession, and the urgent need for true health, time optimization, and mass noncompliance? In this explosive interview, podcast powerhouse Peter McCormack and decentralized neurosurgeon Dr. Jack Kruse dive deep into the UK's dire political crisis, Fabian history from Queen Victoria to World War II, and how cryptography, Zionism, and elite bankers shaped modern money systems. They expose MKUltra's melanin destruction, the Human Genome Project's dark ties to Rockefeller medicine, and why Bitcoin's proof-of-work timestamping is the ultimate weapon against centralized power.Peter reveals his "I No Longer Consent" project to inspire UK citizens to reject oppressive systems through noncompliance, while Dr. Kruse warns of health sabotage via vaccines, fake food, and polarized light—urging Bitcoiners to prioritize time as the scarcest asset over fiat illusions. Discover how reconnecting with nature and embracing Bitcoin's ethos can counter Fabian control, economic theft, and societal decay. For orange-pilled truth-seekers questioning UK politics, history, money manipulation, power dynamics, health hacks, time mastery, noncompliance strategies, and political solutions in a fiat world, this episode is your wake-up call to sovereignty.About Peter McCormack:Host of The Peter McCormack Show and founder of the "I No Longer Consent" movement.X: https://x.com/PeterMcCormackAbout Dr. Jack Kruse:Neurosurgeon and decentralized health expert.X: https://x.com/DrJackKruseChapters:00:00:00 Teaser & Intro Clips00:01:46 State of UK Politics00:04:39 Understanding the Fabians00:05:04 The Role of Cryptography and History00:28:10 The Intersection of Genetics and Control00:41:56 The Value of Time vs. Bitcoin00:47:49 The Bully Pulpit and Responsibility00:53:09 The No Longer Consent Movement00:56:07 Challenging the State and Political Power00:59:32 Reconnecting with Nature and Ambition01:06:42 The Future of the UK and Bitcoin's Role ⚡ POWERED by Abundant Mines: Fully managed Bitcoin mining. Learn more at https://qrco.de/bgYKPB
Contrary to Ordinary, Exploring Extraordinary Personal Journeys
People often take the easy path, but what can you achieve and grow by jumping into thorny problems that don't have an obvious solution?Today's guest on Contrary to Ordinary is Dr. Alex Vieira. He's a pioneer in cleft-palate research, has authored more than 400 scientific papers, and is the most cited expert in the field.In this episode, Alex shares his journey from growing up in Rio de Janeiro during the military regime to becoming a leading figure in oral health research. He discusses his decision to pursue dentistry, influenced by an admired uncle, the challenges of starting his research career during the AIDS epidemic, and his fascination with the Human Genome Project.In this episode's commentary, Kim discusses the importance of the entrepreneurial mindset and the roles of genetics and environment in shaping human behavior. He emphasizes the value of collaboration, the importance of local contributions to global impact, and the need to maintain high research standards. Overall, Alex believes in following one's passion and making meaningful changes in the immediate environment, which he sees as having a trickle-down effect on broader societal improvements.Episode Highlights01:49 –Alex's early life.04:41 – How working with genetics changed the trajectory of Alex's career.08:00 – Kim's thoughts: Surround yourself with those you admire - the rest will follow.08:46 – The Human Genome Project and dentistry.12:10 – The road less travelled and the genetics of extraordinary.14:47 –Kim's thoughts: Can you change your genetic predisposition through forming new habits?15:55 – The complicated world of genetics and dental caries.19:49 – What drives Alex?20:41 – Kim's thoughts: The entrepreneurial mindset isn't just for business people.23:43 –How does Alex maintain a high standard of work?24:47 – What's next for Alex?25:56 – Alex's final thoughts.ResourcesFollow your curiosity, connect, and join our ever-growing community of extraordinary minds.CariFree WebsiteCariFree on InstagramCariFree on FacebookCariFree on PinterestDr. Alex Vieira BioThe Human Genome Project WebsiteThe Power of Habit - Charles DuhiggAtomic Habits: An Easy & Proven Way to Build Good Habits & Break Bad Ones - James Clear
The Year 2000 tried to beat us over our collective noggin with dazzling creations and technological wonderment, and It Happened One Year is there to get wrist deep in the discoveries and doohickeys! Sarah & Joe take a crack at understanding and discussing the Human Genome Project, put that on hold to answer call waiting about the Nokia 3310, pull sunken submarines off the Atlantic floor, discuss the greatest yeast-based children's channel program of the century, get hypnotized by the longest playing song in the world, and then tackle their still-operational Playstation 2 - a segment brought to you with extra crackle! You're welcome!
Can a tethered drone flying 400 feet in the air really replace traditional wind turbines?Rob Creighton, Founder and CEO of Windlift, brings an unconventional background to clean energy innovation. After mapping the human genome as a lab technician, his concerns about peak oil led him to Miles Lloyd's revolutionary 1980 paper on airborne wind energy. "Cut off the tip of a wind turbine blade, attach it to a tether and generate the same electricity with 95% less material," Rob explains. Windlift's tethered drones fly at 400 feet, generating power without towers or massive infrastructure. Can this technology scale beyond defense applications? Rob shares why he's willing to risk everything for climate solutions that protect the Minnesota wilderness where his nephew can no longer play pond hockey.Rob Creighton is the Founder and CEO of Windlift, which he established in 2006 after discovering Miles Lloyd's pioneering research on airborne wind energy. With a BS in Genetics and an MBA in Strategic Management from the University of Wisconsin-Madison, Rob worked as a biologist on the Human Genome Project before pivoting to clean energy innovation. Based in Durham, North Carolina, he has secured over $30 million in contracts with the Naval Research Laboratory and Pentagon, developing tethered autonomous drones that generate electricity with 95% less material than traditional turbines, serving both military and commercial applications.In This Episode: (00:00) Rob Creighton - from mapping human genome to airborne wind(02:45) Windlift's technology explained, tethered drones generating power at altitude(05:28) Peak oil concerns and discovery of Miles Lloyd's groundbreaking paper(10:07) Challenges of airborne wind energy, learning from Makani's failure(15:06) Defense market strategy and working with Pentagon operational energy(19:39) Personal commitment to climate action and wilderness preservationShare with someone who would enjoy this topic, like and subscribe to hear all of our future episodes, send us your comments and guest suggestions!About the show: The Age of Adoption podcast explores the monumental transition from a period of social, economic, and environmental research and exploration – an Age of Innovation – to today's world in which companies across the economy are furiously deploying sustainable solutions – the Age of Adoption. Listen as our host, Keith Zakheim, CEO of Antenna Group, talks with experts from across the climate, energy, health, and real estate sectors to discuss what the transition means for business and society, and how corporates and startups can rise above competitors to lead in this new age. This podcast is brought to you by Antenna Group, a global marketing and communications agency that partners with Fully Conscious brands — those with the courage to lead transformative change across Climate & Energy, Real Estate, Health, and beyond. Our clients include visionary corporations, startups, investors, and nonprofits who recognize that meaningful impact requires more than awareness; it demands bold action. In today's Age of Adoption, where every sector must incorporate sustainable solutions into foundational systems, we amplify brands standing at the forefront of change, shaping a better future for our planet and its people. To learn more, visit antennagroup.com.Resources:Rob Creighton LinkedIn: https://www.linkedin.com/in/rob-creighton-3572702/WindliftAntenna GroupKeith Zakheim LinkedIn
What if the year you lost your job and your mother lost her home became the same year you helped build a $70 million breakthrough in medicine? In this episode of Sharkpreneur, Seth Greene interviews Rome Madison, 3X Best-Selling Author and Keynote Speaker, who shares how growing up with a single mother battling severe mental illness and later homelessness fueled his “no excuses” mindset, and how hand-copying medical textbooks at Barnes & Noble helped him break into precision medicine just as the Human Genome Project was completed. He walks through launching a consulting firm, co-creating the Precision Medicine Podcast that contributed to a $70 million acquisition, and his current work as a confidence coach and host of the global show Genetics for Healthcare, helping high achievers stop second-guessing themselves and expand their impact. Key Takeaways: → The pivotal year when unemployment and a family crisis collided, and why that moment became the catalyst for entering precision medicine. → The unconventional way he prepared for a highly technical role by hand-copying medical and molecular biology content from bookstore shelves. → A plain-language breakdown of what precision medicine actually is, and how it first transformed cancer care through surgical specimens. → Why so many venture-backed precision medicine companies burned through billions, and how that opened the door for his consulting firm. → Behind-the-scenes insights into the $70 million acquisition that included the podcast, and the powerful lessons it taught him about ownership, equity, and value creation. Rome Madison is a dynamic speaker, author, and podcaster who helps people boost self-confidence, face fears, embrace uncertainty, and cut through chaos to achieve bold, ambitious goals. Known for his high-energy delivery and inspiring message, he empowers audiences to take risks and pursue success with fearless determination. A pioneer in the precision medicine industry, Rome draws from extensive sales management and executive leadership experience, sharing powerful lessons from leading massively successful start-ups to navigating the challenges of corporate collapse and restructuring. A futurist with a Specialty in Business Strategy from Harvard Business School Online, he blends forward-thinking insight with real-world expertise. Featured on more than 50 TV and radio programs nationwide, Rome has spoken on global stages, including the Consumer Electronics Show, where he shared his expertise on the Future of Healthcare. His mission is simple yet profound: inspire people to crush their goals, no matter the obstacles. Connect With Rome : Website: https://romemadison.com/ Instagram: https://www.instagram.com/romemadisoneverydaysuperstar/ Youtube: https://www.youtube.com/@RomeMadison X: https://x.com/RomeMadison Facebook: https://www.facebook.com/TheEverydaySuperstar LinkedIn: https://www.linkedin.com/in/genomicsellingsolutions/ Learn more about your ad choices. Visit megaphone.fm/adchoices
What if the year you lost your job and your mother lost her home became the same year you helped build a $70 million breakthrough in medicine? In this episode of Sharkpreneur, Seth Greene interviews Rome Madison, 3X Best-Selling Author and Keynote Speaker, who shares how growing up with a single mother battling severe mental illness and later homelessness fueled his “no excuses” mindset, and how hand-copying medical textbooks at Barnes & Noble helped him break into precision medicine just as the Human Genome Project was completed. He walks through launching a consulting firm, co-creating the Precision Medicine Podcast that contributed to a $70 million acquisition, and his current work as a confidence coach and host of the global show Genetics for Healthcare, helping high achievers stop second-guessing themselves and expand their impact. Key Takeaways: → The pivotal year when unemployment and a family crisis collided, and why that moment became the catalyst for entering precision medicine. → The unconventional way he prepared for a highly technical role by hand-copying medical and molecular biology content from bookstore shelves. → A plain-language breakdown of what precision medicine actually is, and how it first transformed cancer care through surgical specimens. → Why so many venture-backed precision medicine companies burned through billions, and how that opened the door for his consulting firm. → Behind-the-scenes insights into the $70 million acquisition that included the podcast, and the powerful lessons it taught him about ownership, equity, and value creation. Rome Madison is a dynamic speaker, author, and podcaster who helps people boost self-confidence, face fears, embrace uncertainty, and cut through chaos to achieve bold, ambitious goals. Known for his high-energy delivery and inspiring message, he empowers audiences to take risks and pursue success with fearless determination. A pioneer in the precision medicine industry, Rome draws from extensive sales management and executive leadership experience, sharing powerful lessons from leading massively successful start-ups to navigating the challenges of corporate collapse and restructuring. A futurist with a Specialty in Business Strategy from Harvard Business School Online, he blends forward-thinking insight with real-world expertise. Featured on more than 50 TV and radio programs nationwide, Rome has spoken on global stages, including the Consumer Electronics Show, where he shared his expertise on the Future of Healthcare. His mission is simple yet profound: inspire people to crush their goals, no matter the obstacles. Connect With Rome : Website: https://romemadison.com/ Instagram: https://www.instagram.com/romemadisoneverydaysuperstar/ Youtube: https://www.youtube.com/@RomeMadison X: https://x.com/RomeMadison Facebook: https://www.facebook.com/TheEverydaySuperstar LinkedIn: https://www.linkedin.com/in/genomicsellingsolutions/ Learn more about your ad choices. Visit megaphone.fm/adchoices
Breath to Breath Film that celebrates the contributions by Dr. Michael WelshA Conversation with Dr. Michael Welsh: The Science That is Saving LivesIt's always such a privilege to feature CF icons on the podcast. Over the years, we've been fortunate to host some of the most influential names in cystic fibrosis research, including Dr. Francis Collins, the former director of the NIH and one of the authors of the Human Genome Project, and his longtime friend Dr. Mitch Drumm, who was working on his doctorate when the CF gene was discovered back in 1989.I actually saw Mitch recently at a dinner, and as many of you know, Dr. Collins continues to be a tireless advocate for good science and for sharing its importance with the world.And now, we add another legend to that list: Dr. Michael Welsh from the University of Iowa.Dr. Welsh tells his story beautifully in the University's film Breath by Breath: Living with Cystic Fibrosis. In it, he describes how his curiosity about the CFTR protein led to groundbreaking discoveries that ultimately laid the foundation for CF therapies, the very treatments that have changed (and saved) thousands of lives, including the lives of my daughters.Dr. Welsh's career is extraordinary, spanning decades of research, mentorship, and discovery. He's the Carver Professor of Internal Medicine and Molecular Physiology and Biophysics at the University of Iowa, and from 1989 to 2024, he served as an Investigator with the Howard Hughes Medical Institute. He currently directs both the Pappajohn Biomedical Institute and the Cystic Fibrosis Research Center.We've linked both his full bio and the film in the show notes, and I highly encourage you to check them out. His accolades could fill pages, actually, an entire book! We had so many laughs too in this podcast! So much fun. You'll really enjoy it.Dr. Welsh shared insights not only into his scientific journey, but also the heart behind the work. He recently received the Lasker Award for pioneering CF research that led to life-saving therapies, a recognition that celebrates decades of persistence, curiosity, and collaboration.We discussed so much:How his team began unraveling the mystery of the CFTR protein and what that breakthrough moment felt likeWhat it's like to see patients thriving because of the treatments that grew from that workWhy the University of Iowa decided to produce Breath by Breath, and what the film means to him personallyWhat new treatments and discoveries he's exploring nowHearing Dr. Welsh describe the intersection of science, hope, and humanity is powerful. You can tell that for him, this work isn't just research, it's a mission.As the documentary shows, CF isn't just a disease studied under a microscope. It's a lived experience for patients and families, one that now includes real hope thanks to the breakthroughs made by scientists like Dr. Michael Welsh.Biography:Dr. Michael Welsh is the Carver Professor of Internal Medicine and Molecular Physiology andBiophysics at the University of Iowa. From 1989-2024, he was an Investigator of the HowardHughes Medical Institute. He directs the Pappajohn Biomedical Institute and the Cystic FibrosisResearch Center.Dr. Welsh obtained an MD and completed an internal medicine residency at the University ofIowa. He then trained in pulmonary medicine and research at the University of California, SanFrancisco and physiology at the University of Texas, Houston.Dr. Welsh and his colleagues discovered that the protein affected in cystic fibrosis is an anionchannel, elucidated its functional mechanisms, discovered ways that mutations disrupt function,and showed that mutations can be rescued. This work led directly to development of medicinesthat target CFTR and are highly effective for most cystic fibrosis patients. To understand diseasepathogenesis, he and his collaborators developed cystic fibrosis pigs, the first mammal, otherthan mice, in which a gene was targeted to generate a disease model.His clinical activities focused on pulmonary diseases. He has trained many physicians andscientists and received the Distinguished Mentor Award, University of Iowa Carver College ofMedicine.To watch the film, click here: https://uihealthcare.org/cystic-fibrosis-research-iowa#documentaryTo learn more about Dr. Welsh: https://internalmedicine.medicine.uiowa.edu/profile/michael-welsh Please like, subscribe, and comment on our podcasts!Please consider making a donation: https://thebonnellfoundation.org/donate/The Bonnell Foundation website:https://thebonnellfoundation.orgEmail us at: thebonnellfoundation@gmail.com Watch our podcasts on YouTube: https://www.youtube.com/@laurabonnell1136/featuredThanks to our sponsors:Vertex: https://www.vrtx.comViatris: https://www.viatris.com/en
"My ideas are often labelled as impossible, or useless, or both. Usually when people say that I'm on the right track." George Church is a geneticist, molecular engineer, and one of the pioneers of modern genomics. He's also someone who makes a habit of finding solutions to the seemingly impossible. Over the course of his career so far, George developed the first method for direct genomic sequencing, helped initiate the Human Genome Project, and founded the Personal Genome Project: making huge quantities of DNA data publicly available for research. Today, as a professor at Harvard Medical School and MIT, he's working on some of the most headline-grabbing - and controversial - science on the planet: from the so-called "de-extinction" of woolly mammoths, to growing transplant-suitable organs in pigs, to virus-proofing humans. When inspiration strikes, there seems to be little that will slow him down - even the fact that he has narcolepsy, the neurological disorder that causes sudden sleep attacks. In fact, as George tells Professor Jim Al-Khalili, some of his best ideas come in those moments between waking and sleep...
Twenty-five years ago, President Bill Clinton stood before a podium in the East Room of the White House, and, in front of an all-star lineup of researchers and dignitaries, made a historic announcement: After years of painstaking work, scientists had created “the most important, most wondrous map ever produced by humankind” — the first-ever survey of the human genome.In his remarks, Clinton compared the achievement to the maps created by Lewis and Clark's expedition into the American West — but maybe a comparison to the space race would have been more accurate. Because, behind the scenes, the journey leading up to that day's announcement had been defined by nerve-wracking, cut-throat competition — a competition where every minute counted, and the future of scientific inquiry was at stake.On this encore episode, we look back at how what started as a scientific collaboration fractured into a bitter race to finish decoding the human genome. On one side was the federally funded Human Genome Project; on the other, a private start-up called Celera; and, in between, a raucous mashup of conflicting personalities, values, and ideas that would eventually help to transform science and medicine.
In this special episode of Robin's Nest, we're joined by Dr. George Church, a world-renowned geneticist and one of the leading minds behind the Human Genome Project, for a conversation about the amazing ways science is helping us understand, protect and even restore life on Earth.Dr. Church takes us inside the frontier of synthetic biology, from the origins of CRISPR and gene editing to the bold promise of de-extinction, conservation technology and genetic equity. The discussion spans his groundbreaking work with Colossal Biosciences, where efforts to revive the woolly mammoth and other lost species aim to restore ecosystems and rethink what “saving nature” means in the 21st century.Listeners will hear Dr. Church reflect on the ethics and responsibilities of rewriting life's code, the potential for genetic engineering to combat biodiversity loss, and why he believes “extinction doesn't have to be forever.” This episode explores how technology and conservation can work hand-in-hand to heal the planet.A fascinating journey into the science shaping our shared future, and a reminder that innovation, guided by compassion and curiosity, may yet help us write a better story for life on Earth.
We've entered a new age. Where nature once took a million years to make a few genetic changes, scientists can now make billions in an afternoon — and even imagine adapting humans for life beyond Earth.George Church, a Harvard geneticist, pioneer of the Human Genome Project, and founder of more than 50 biotech companies, helped lay the foundation for CRISPR, personal genomics, and even de-extinction.In this episode, he explains how biotechnology, AI, and materials science are converging to transform life itself - from reversing aging and curing disease to resurrecting lost species like the woolly mammoth, and one day, helping humanity thrive among the stars.
"My ideas are often labelled as impossible, or useless, or both. Usually when people say that I'm on the right track."George Church is a geneticist, molecular engineer, and one of the pioneers of modern genomics. He's also someone who makes a habit of finding solutions to the seemingly impossible.Over the course of his career so far, George developed the first method for direct genomic sequencing, helped initiate the Human Genome Project, and founded the Personal Genome Project: making huge quantities of DNA data publicly available for research. Today, as a professor at Harvard Medical School and MIT, he's working on some of the most headline-grabbing - and controversial - science on the planet: from the so-called "de-extinction" of woolly mammoths, to growing transplant-suitable organs in pigs, to virus-proofing humans.When inspiration strikes, there seems to be little that will slow him down - even the fact that he has narcolepsy, the neurological disorder that causes sudden sleep attacks. In fact, as George tells Professor Jim Al-Khalili, some of his best ideas come in those moments between waking and sleep...Presented by Jim Al-Khalili Produced by Lucy Taylor for BBC Studios
It's common knowledge that many diseases and conditions have some kind of genetic link. But that wasn't always the case. In 1990, long before the Human Genome Project tied so many health issues to differences in genetics, researchers identified a gene called BRCA1. It was the first gene linked to a hereditary form of any common cancer. People with certain variants of BRCA1 stood a higher risk of developing breast and ovarian cancer than those without those mutations. Geneticist Mary-Claire King and her lab were the first to identify that gene. She joins Host Flora Lichtman to talk about her background, her research, and her approach to science.Guest: Dr. Mary-Claire King is an American Cancer Society Professor in the departments of Genome Sciences and Medicine at the University of Washington in Seattle.Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
What happens when you combine groundbreaking genetic research with deep spiritual wisdom? Meet Francis Collins - the physician-geneticist who led the Human Genome Project, directed the NIH under five presidents, and helped develop the cure for cystic fibrosis. In this fascinating conversation, Francis reveals how he searches for three missing letters among 3 billion, why the COVID vaccine represents one of science's greatest achievements, and how faith and science enhance rather than conflict with each other. From his insights on presidential wisdom to his prescription for healing our divided nation, Francis shares lessons from his book "The Road to Wisdom" that challenge how we think about truth, trust, and what it means to be truly wise.---Guy Kawasaki is on a mission to make you remarkable. His Remarkable People podcast features interviews with remarkable people such as Jane Goodall, Marc Benioff, Woz, Kristi Yamaguchi, and Bob Cialdini. Every episode will make you more remarkable.With his decades of experience in Silicon Valley as a Venture Capitalist and advisor to the top entrepreneurs in the world, Guy's questions come from a place of curiosity and passion for technology, start-ups, entrepreneurship, and marketing. If you love society and culture, documentaries, and business podcasts, take a second to follow Remarkable People.Listeners of the Remarkable People podcast will learn from some of the most successful people in the world with practical tips and inspiring stories that will help you be more remarkable.Episodes of Remarkable People organized by topic: https://bit.ly/rptopologyListen to Remarkable People here: **https://podcasts.apple.com/us/podcast/guy-kawasakis-remarkable-people/id1483081827**Like this show? Please leave us a review -- even one sentence helps! Consider including your Twitter handle so we can thank you personally!Thank you for your support; it helps the show!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Public Health Careers podcast episode with Tim Leshan, MPAIn this episode, Tim Leshan, MPA, Chief External Relations and Advocacy Officer for the Association of Schools and Programs of Public Health, discusses the importance of public health advocacy, the economic impact of public health initiatives, and the need for effective communication with policymakers. He shares insights on building public-private partnerships, navigating challenges in the current political landscape, and the significance of education and storytelling in public health. Tim emphasizes the importance of hope and engagement for young professionals in the field, while also reflecting on his personal journey and career development in public health advocacy.
In this edition of The Naked Scientists, we look at 25 years of the Human Genome Project. What is it? And what has it achieved? Like this podcast? Please help us by supporting the Naked Scientists
In this episode of the Epigenetics Podcast, we talked with Sarah Teichmann from the University of Cambridge about the Human Cell Atlas. In the Interview we explore Sarah Teichmann's impressive career trajectory, covering her current role as Chair of Stem Cell Medicine at the Cambridge Stem Cell Institute and Vice President of Translational Research at GlaxoSmithKline. Professor Teichmann explains her unique dual appointments, a rare arrangement that allows her to bridge academia and industry effectively. As the conversation shifts focus to computational biology, she takes us on a historical journey from her PhD work at the MRC Laboratory of Molecular Biology to the present advancements driven by next-generation sequencing and artificial intelligence methods. Professor Teichmann emphasizes that the landscape of biological research has evolved significantly, particularly in the realm of data-driven methodologies. The conversation then transitions seamlessly into her pivotal role in advancing single-cell genomics, where she discusses the motivation behind using single-cell RNA sequencing methods in her research on T cells. This technique offered unmatched insights compared to bulk sequencing techniques, allowing for a more detailed understanding of cell states and their complex interactions within tissues. A highlight of the episode is Professor Teichmann's insights on the Human Cell Atlas project, which she co-founded in 2017. She elaborates on the ambitious vision to map all human cells, likening the endeavor to the Human Genome Project. Through the atlas, researchers aim to create a detailed reference map that facilitates a deeper understanding of human health and disease. Professor Teichmann shares the collaborative efforts that led to its inception and the importance of international cooperation in scientific research. The discussion culminates with an exploration of the biggest scientific findings thus far from the Human Cell Atlas. Among the revelations, she notes the astounding complexity and diversity of cell types identified, particularly within the immune system, and the unexpected locations of certain cell types during human development. She also highlights significant discoveries related to COVID-19, demonstrating the immediate real-world impact of their work. References https://www.humancellatlas.org The Human Cell Atlas: towards a first draft atlas Kock, K. H., Tan, L. M., Han, K. Y., Ando, Y., Jevapatarakul, D., Chatterjee, A., Lin, Q. X. X., Buyamin, E. V., Sonthalia, R., Rajagopalan, D., Tomofuji, Y., Sankaran, S., Park, M. S., Abe, M., Chantaraamporn, J., Furukawa, S., Ghosh, S., Inoue, G., Kojima, M., Kouno, T., … Prabhakar, S. (2025). Asian diversity in human immune cells. Cell, 188(8), 2288–2306.e24. https://doi.org/10.1016/j.cell.2025.02.017 Related Episodes The Discovery of Genomic Imprinting (Azim Surani) Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com
It has been 25 years since Bill Clinton announced one of humanity's most important scientific achievements: the first draft of the human genome. At the time, there was a great deal of excitement about the benefits that this new knowledge would bring, with predictions about curing genetic diseases and even cancer. To find out which of them came to pass, and what could be in store over the next two-and-a-half decades, Madeleine Finlay is joined by science editor Ian Sample, and hears from Prof Matthew Hurles, director of the Wellcome Sanger Institute. Help support our independent journalism at theguardian.com/sciencepod
The Human Genome Project is one of the greatest scientific feats in history. It was launched in 1990 and completed in 2003. The international group of researchers wanted to comprehensively study all of the DNA – the genome – from a select set of organisms, foremost of which being that of human beings. The results […]
Biological justification for all forms of inequality has a long history, with the claim that particular groups suffer disproportionately from inherited flaws of ability and character used to explain a remarkably wide variety of inequalities. Providing an important critique of that biodeterminist history and how the Human Genome Project has inspired some contemporary scientists and economists to follow a similar path of ascribing socioeconomic outcomes to genetic inheritance, The American Gene: Unnatural Selection Along Class, Race, and Gender Lines (Routledge, 2025) details new research that suggests that the social and economic environment can affect how genes express themselves in specific human traits and social outcomes. Using the three cases of the American white working class, Black Americans and American women, the authors demonstrate that relying on nature as an explanation is seriously flawed - showing that the socioeconomic inheritance created by the conditions in which these populations worked and lived offer a far better explanation than nature for the stratified results. This book is the story of an American history rife with unnecessary misery and the waste of human potential, along with the liberating effect of understanding the degree to which its citizens are the product of social inheritance and the potential power of a nurturing economy and society that equality promises. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network
Today astrophysicist Dr. Mario Livio and Nobel-winning chemist Dr. Jack Szostak drop in to talk about the search for extraterrestrial life.About our guests:Dr. Mario Livio is an internationally known astrophysicist, best-selling author, and popular speaker. He is a Fellow of the American Association for the Advancement of Science. Dr. Livio has published more than 500 scientific articles. He has made significant theoretical contributions to topics ranging from cosmology, supernova explosions, and black holes to extrasolar planets and the emergence of life in the universe. He has received numerous awards and recognitions for his research, including having been selected as the “Carnegie Centenary Professor” by the universities of Scotland in 2003, and as the “Danz Distinguished Lecturer” by the University of Washington in 2006. Dr. Livio is also the author of eight popular science books, the most recent in collaboration with Nobel laureate Jack Szostak. His bestselling book The Golden Ratio won him the Peano Prize in 2003 and the International Pythagoras Prize in 2004, as the best popular book on mathematics. His book Is God A Mathematician? inspired the NOVA program “The Great Math Mystery,” which was nominated for an EMMY in 2016. His book Brilliant Blunders was selected by The Washington Post as one of the Notable Books of 2013. His book Galileo and the Science Deniers appeared in May 2020, and was one of the finalists for the Phi Beta Kappa Award in Science. Dr. Jack Szostak is a biologist, Nobel Prize laureate, university professor at the University of Chicago, former professor of genetics at Harvard Medical School, and Alexander Rich Distinguished Investigator at Massachusetts General Hospital, Boston. Szostak has made significant contributions to the field of genetics. His achievement helped scientists to map the location of genes in mammals and to develop techniques for manipulating genes. His research findings in this area are also instrumental to the Human Genome Project. He was awarded the 2009 Nobel Prize for Physiology or Medicine, along with Elizabeth Blackburn and Carol W. Greider, for the discovery of how chromosomes are protected by telomeres.
This is a free preview of a paid episode. To hear more, visit andrewsullivan.substack.comFrancis is a physician and geneticist whose work has led to the discovery of the cause of cystic fibrosis, among other diseases. In 1993 he was appointed director of the Human Genome Project, which successfully sequenced all three billion letters of our DNA. He went on to serve three presidents as the director of the National Institutes of Health. The author of many books, including The Language of God, his latest is The Road to Wisdom: On Truth, Science, Faith, and Trust.Our conversation was entirely agreeable until we talked about trust, and his own handling of the Covid epidemic. I asked him in depth about the lab-leak theory and why he and Tony Fauci passionately dismissed it from the get-go, even as it now appears to be the likeliest source of the terrible virus. Things got intense.For two clips of our convo — intense debate on the “Proximal Origin” paper outright denying a lab leak as the source of Covid-19, and Francis finding God after decades of atheism — pop over to our YouTube page.Other topics: growing up on a rustic farm in Shenandoah; his parents creating a community theater; homeschooled until 6th grade; his amazing scientific accomplishments as a young adult; his scientism; his terminally ill Christian patients; the AIDS crisis; C.S. Lewis' Mere Christianity; the First Mover question; Ross Douthat and “fine-tuning”; the multiverse; the limits to the materialist view; deism; cradle believers vs converts; evolution and sacrificial altruism; Socrates; Jesus dying for our sins; the doubting Thomas; how angels manifest; Francis Bacon; Richard Dawkins; being the NIH director during Covid; trust and mistrust in science; the early confusion in pandemics; tribalism; dismal safety standards at the Wuhan lab; gain-of-function; EcoHealth and Peter Daszak; intel agencies on lab leak; furin cleavage sites; Kristian Andersen; geopolitical fears over Trump and China; the opacity of the CCP; the Great Barrington Declaration; Trump threatening science funding at the Ivies; In Covid's Wake; and if Francis has any regrets after Covid.Browse the Dishcast archive for an episode you might enjoy (the first 102 are free in their entirety — subscribe to get everything else). Coming up: Claire Lehmann on the woke right, Stephen Macedo and Frances Lee on Covid's political fallout, Byron York on Trump 2.0, Robert Merry on President McKinley, Sam Tanenhaus on Bill Buckley, Jake Tapper and Alex Thompson on the Biden years, and Paul Elie on his book The Last Supper: Art, Faith, Sex, and Controversy in the 1980s. Please send any guest recs, dissents, and other comments to dish@andrewsullivan.com.
The genetic testing firm 23andMe has filed for bankruptcy, another twist in the story of a company that promised a pioneering approach to precision health. Now users are scrambling to delete their personal data, with the future ownership of the firm uncertain. To understand the highs and lows of 23andMe's journey, Madeleine Finlay hears from the Guardian US tech reporter and editor Johana Bhuiyan, and from Timothy Caulfield, a professor of law at the University of Alberta, who has a special interest in health and biotechnology. Help support our independent journalism at theguardian.com/sciencepod
This is our unabridged interview with Francis Collins. Francis Collins has led some of the most significant scientific initiatives of our time, including the Human Genome Project and the National Institutes of Health under three U.S. presidents. In his new book, The Road to Wisdom, Collins grapples with the erosion of public trust in science, the polarization of society, and the challenge of discerning truth in the modern age. In this conversation, Collins shares insights from his experiences during the COVID-19 pandemic, his journey from atheism to Christian faith, and the importance of humility in the pursuit of knowledge. He reflects on his unlikely friendship with the late atheist Christopher Hitchens, the philosophical roots of truth skepticism, and the need for genuine dialogue across divides. Join us as we explore how wisdom, truth, science, and faith intersect—and why curiosity and compassion might just be the antidote to our age of distrust. Show Notes Resources: "The Road to Wisdom" by Francis Collins Similar NSE episodes: Quincy Byrdsong: Tuskegee, Healthcare, Justice Jennifer Wiseman: How Science Produces Wonder David Wilkinson: The (Not Really) War Between Science and Faith Rachel Held Evans, Francis Collins, and Ed Larson: Faith, Science, Humility PDF of Lee's Interview Notes Transcript of Abridged Episode Want more NSE? JOIN NSE+ Today! Our subscriber only community with bonus episodes designed specifically to help you live a good life, ad-free listening, and discounts on live shows Great Feeling Studios, the team behind No Small Endeavor and other award-winning podcasts, helps nonprofits and brands tell stories that inspire action. If your organization has a message that deserves to be heard, start your podcast at helpmemakeapodcast.com. Subscribe to episodes: Apple | Spotify | Amazon | Google | YouTubeFollow Us: Instagram | Twitter | Facebook | YouTubeFollow Lee: Instagram | TwitterJoin our Email List: nosmallendeavor.com See Privacy Policy: Privacy Policy Amazon Affiliate Disclosure: Tokens Media, LLC is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn adverti… Learn about your ad choices: dovetail.prx.org/ad-choices
Francis Collins has led some of the most significant scientific initiatives of our time, including the Human Genome Project and the National Institutes of Health under three U.S. presidents. In his new book, The Road to Wisdom, Collins grapples with the erosion of public trust in science, the polarization of society, and the challenge of discerning truth in the modern age. In this conversation, Collins shares insights from his experiences during the COVID-19 pandemic, his journey from atheism to Christian faith, and the importance of humility in the pursuit of knowledge. He reflects on his unlikely friendship with the late atheist Christopher Hitchens, the philosophical roots of truth skepticism, and the need for genuine dialogue across divides. Join us as we explore how wisdom, truth, science, and faith intersect—and why curiosity and compassion might just be the antidote to our age of distrust. Show Notes Resources: "The Road to Wisdom" by Francis Collins Similar NSE episodes: Quincy Byrdsong: Tuskegee, Healthcare, Justice Jennifer Wiseman: How Science Produces Wonder David Wilkinson: The (Not Really) War Between Science and Faith Rachel Held Evans, Francis Collins, and Ed Larson: Faith, Science, Humility PDF of Lee's Interview Notes Transcription Link Want more NSE? JOIN NSE+ Today! Our subscriber only community with bonus episodes designed specifically to help you live a good life, ad-free listening, and discounts on live shows Great Feeling Studios, the team behind No Small Endeavor and other award-winning podcasts, helps nonprofits and brands tell stories that inspire action. If your organization has a message that deserves to be heard, start your podcast at helpmemakeapodcast.com. Subscribe to episodes: Apple | Spotify | Amazon | Google | YouTubeFollow Us: Instagram | Twitter | Facebook | YouTubeFollow Lee: Instagram | TwitterJoin our Email List: nosmallendeavor.com See Privacy Policy: Privacy Policy Amazon Affiliate Disclosure: Tokens Media, LLC is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sit… Learn about your ad choices: dovetail.prx.org/ad-choices
The #1 killer in the world is heart disease—it doesn't matter who you are or where you live, this killer doesn't discriminate. But does it have a code? And could it be cracked with the right technology? Tune in to discover: Why all of our cells would burst without cholesterol, but what happens when there's too much of it How CRISPR/Cas9 technology could hold the key to permanently low cholesterol levels (without the need for injections or pills), and a cure for sickle cell anemia What lipid nanoparticles are, how they can be used to deliver genes to specific organs in the body, and why this is significant Dr. Kiran Musunuru is a cardiologist, professor of medicine, and director of the Genetic and Epigenetic Origins of Disease Program at Perelman School of Medicine, University of Pennsylvania. As the leading cause of death globally, he believes heart disease is the preeminent global health threat of the 21st century, and the greatest challenge facing the medical profession today. And this is driving him to take action. Dr. Musunuru explains that, despite immense efforts put forth by some of the brightest scientists and doctors over the course of decades, treatment options for heart disease remain limited, mostly to cholesterol-lowering drugs. But he also explains how this is changing in light of the more recent revolution in genetics—namely, the completion of the Human Genome Project. What's the genetic difference between those who develop heart disease and those who don't? What genes influence heart health and disease, and could therapies based on this information prevent heart disease altogether? These are the types of questions that Dr. Musunuru says can now be answered, and he's doing just that. Listeners will learn about the genetics behind heart disease and cholesterol levels, the details of Dr. Musunuru's research and most recent findings, what the future of heart disease treatment and prevention might hold, and much more. Learn more at https://www.med.upenn.edu/cvi/musunuru-laboratory.html. Episode also available on Apple Podcasts: http://apple.co/30PvU9 Upgrade Your Wallet Game with Ekster! Get the sleek, smart wallet you deserve—and save while you're at it! Use coupon code FINDINGGENIUS at checkout or shop now with this exclusive link: ekster.com?sca_ref=4822922.DtoeXHFUmQ5 Smarter, slimmer, better. Don't miss out!
The Human Genome Project was a massive undertaking that took more than a decade and billions of dollars to complete. For it, scientists collected DNA samples from anonymous volunteers who were told the final project would be a mosaic of DNA. Instead, over two-thirds of the DNA comes from one person: RP11. No one ever told him. Science journalist Ashley Smart talks to host Emily Kwong about his recent investigation into the decision to make RP11 the major donor — and why unearthing this history matters to genetics today.Read Ashley's full article in Undark Magazine here.Questions or ideas for future episodes? Email us at shortwave@npr.org.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy