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Scott Morris, Branch Manager at Ross Mortgage Corporation, and Jake McNemar, Realtor at eXp Realty, joined Keith Smith and me on “Real Talk With Keith Smith” powered by YES Realty Partners and Yonna Smith! “Real Talk” airs every Monday, Wednesday and Friday from 10:15 am – 11 am on The I Love CVille Network! “Real Talk With Keith Smith” is presented by Ally Property Management, American Pest, BC Harrop Photo LLC, Charlottesville Settlement Company, LLC, Choice Home Inspections, Closure Title & Settlement Co., Fincham & Associates, Inc., Free Enterprise Forum, Intrastate Service Co, Keller Williams Alliance, Pearl Certification, Ross Mortgage Corporation, Sigora Solar, Stanley Martin Homes and YES Realty Partners.
Guest Heather McNemar experienced a taste of world travel while in high school, when her father took a sabbatical and the family visited many spots, including Siberia for a slightly extended stay. Heather was drawn to the language and the culture and knew she would study both in college. Later, as she was making her way into the world, she didn't know exactly how she would use her skills but knew she wanted to help people. She got a job helping newly settled immigrants to the U.S. get jobs and realized that good language skills were key to their success. She began taking classes to teach English as a Second Language and landed a spot as a Peace Corps volunteer in Kazakhstan. While there, she met the man who would become her husband, also a Peace Corps volunteer but had his sights set on diplomatic work with the U.S. Department of State.In this episode, find out from Heather how finding your way in a new place can also help others do likewise…on Roads Taken with Leslie Jennings Rowley. About This Episode's GuestHeather McNemar is a former Peace Corps volunteer who has gone round this girdled earth a number of times with her family as her husbnad has been posted with the U.S. State Department. Her fluency in Russian and her expertise in helping others find their footing in new places and new careers has been helpful in many of her posts. She is currently in the middle of a stint in Tashkent, Uzbekistan, and continues running, finding that it is often a great way to get to know a new place. For another story about the peripatetic life that comes with a State Department gig, listen to our episode with Joey Hood.Find more episodes at https://roadstakenshow.com Executive Producer/Host: Leslie Jennings RowleyMusic: Brian BurrowsEmail the show at RoadsTakenShow@gmail.com
Jon McNemar is a Sports Performance Coach at Duke University. He joined the Blue Devils in July of 2021 and works directly with the field hockey, track & field sprints-jumps groups, as well as men's tennis team. McNemar previously worked at Jacksonville University where in 2015 he worked his way from intern to graduate assistant before being promoted to a full-time assistant strength coach in 2018. He also spent part of the 2018 season as an intern with the Florida State University football program. McNemar was an offensive lineman and four-year letter winner on the Fairmont State University football team. He was awarded the “Iron Falcon Award” which is given to the strongest and most dedicated offensive/defensive lineman in the weight room. His dedication to training following his football career saw him compete in push-pull competitions and still continues to train while balancing the rigors of the collegiate coaching schedule. Samson Equipment Samson Equipment provides Professional Weight Room Solutions for all your S&C needs.Cerberus Strength Use Code: STRENGTH_GAME at Cerberus-Strength.com
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.21.262147v1?rss=1 Authors: Silva, R., Padovani, K., Goes, F., Alves, R. Abstract: Motivation: Microbes perform a fundamental economic, social and environmental role in our society. Metagenomics makes it possible to investigate microbes in their natural environments (the complex communities) and their interactions. The way they act is usually estimated by looking at the functions they play in those environments and their responsibility is measured by their genes. The advances of next-generation sequencing technology have facilitated metagenomics research however it also create a heavy computational burden. Large and complex biological datasets are available as never before. There are many gene predictors available which can aid gene annotation process though they lack of handling appropriately metagenomic data complexities. There is no standard metagenomic benchmark data for gene prediction. Thus, gene predictors may inflate their results by obfuscating low false discovery rates. Results: We introduce geneRFinder, a ML-based gene predictor able to outperform state-of-the-art gene prediction tools across this benchmark by using only one pre-trained Random Forest model. Average prediction rates of geneRFinder differed in percentage terms by 54% and 64%, respectively, against Prodigal and FragGeneScan while handling high complexity metagenomes. The specificity rate of geneRFinder had the largest distance against FragGeneScan, 79 percentage points, and 66 more than Prodigal. According to McNemar's test, all percentual differences between predictors performances are statistically significant for all datasets with a 99% confidence interval. Conclusions: We provide geneRFinder, a approach for gene prediction in distinct metagenomic complexities, available at github.com/railorena/geneRFinder, and also we provide a novel, comprehensive benchmark data for gene prediction --- which is based on The Critical Assessment of Metagenome Interpretation (CAMI) challenge, and contains labeled data from gene regions -- avaliable at sourceforge.net/p/generfinder-benchmark . Copy rights belong to original authors. Visit the link for more info
Acil servise başvuran hastanın klinik durumu ne olursa olsun ilk yaptığımız şey ABC’nin devamlılığını sağlamaktır. Acil tıp hekimlerinin gerek servislerinde gerekse de servis/hastane dışı vakalarındaki en önemli uğraş alanı; hava yolunu açmak ve güvenli bir şekilde devamlılığını sağlamaktan geçer. En çok kullandığımız ve en iddialı olduğunu düşündüğümüz endotrakeal entübasyon yöntemi bazı durumlarda çok da kolay değildir. Toplumda sık kullanılan “ağzının içine bakmak” deyiminin acilci için anlamı; “bu hasta kolay mı entübe olur yoksa zor mu?” desek çok mu abartmış olurum. [box type="info" align="aligncenter" class="" width=""]ZOR HAVAYOLU deneyimli bir doktorun, hastasını maske ile havalandırmada veya trakeal entübasyonda ya da her ikisinde birden karşılaştığı zorluk olarak tanımlanmaktadır. [/box] Tüm bunlar bir yana ister kritik olsun isterse planlı entübasyon olsun, bir hastanın zor entübasyon olduğunu sadece öngörüye bırakmadan, işlem esnasında ne kadar zorlanacağımızı tahmin ettiren bazı formüller geliştirilmiştir. Zor havayolu tesbitinde acil serviste en çok kullandığımız yöntemler arasında; “LEMON”, Cormeck-lehane sınıflaması ve tiromental mesafe ölçümü yer alır.[toggle title="LEMON" state="close"]L (Look), inspeksiyon ile hastayı değerlendirme ( obezite, kısa boyun, küçük çene, büyük dil vb), 3-3-2 kuralı, mallampati skoru, obstrüksiyon ve boyun hareketliliğini değerlendirir.[/toggle] Cormack-Lehane sınıflandırma Acil serviste hasta başında zor havayolunu tanımlamak için başucu testi yapmak klinik uygulamanın bir parçasıdır. Bu testler tarama testleri olarak kabul edilir; yani, tüm zor hava yolu vakalarını tanımlamak için yüksek hassasiyete sahip olması (duyarlılığı yüksek), ancak zor hava yolu olmayanları tanımlamak için daha düşük özgüllüğe (spesifitesi düşük) sahip olması beklenmektedir. Bugün sizlerle kritik hastada kullanırken zorlanabileceğimiz ama uyanık hastanın havayolunu değerlendirirken bize hız katabileceğini düşündüğüm farklı bir testten; Üst Dudak Isırma Testi (ÜDIT)’ nden bahsetmek istiyorum. 2003 yılında Khan ve ark çalışmasında oluşturulan bu testin sınıflaması şu şekilde; hasta alt kesici dişleri ile üst dudağını vermillion’un üstünden ısırılabiliyorsa sınıf 1, alt kesicileri ile üst dudağını vermillion’un altından ısırabiliyorsa sınıf 2, alt kesiciler ile üst dudağı ısıramıyorsa sınıf 3 olarak yapılmış. Rakam arttıkça zorluk da doğru orantılı olarak artıyor. 11 ay boyunca, genel anestezi alacak olan, 16 yaş ve üzeri ardışık hastalar çalışmaya dahil edilmiş. Dişi olmayan hastalar, ağız açıklığını sağlayamayanlar, laringeal kitlesi olanlar ve boyun hareketi kısıtlı olan hastalar çalışmadan çıkartılmış. Entübasyon sürecinde yer almayan iki anestezist, hastaları ÜDİT ve Modifiye Mallampati Testine (MMT) göre değerlendirmiş. Hastaların preoperatif değerlendirilmesinde yer almayan diğer anestezistler ise, entübasyon esnasında entübasyon zorluğunu Cormack-Lehane sınıflamasına göre değerlendirmiş. Entübasyon öncesi ve entübasyon esnasındaki değerlendirmeler karşılaştırılarak söz konusu skorların doğruluğu açısından analiz edilmesi hedeflenmiş. 300 hasta çalışmaya dahil edilmiş. 17'si (%5.7) entübasyon esnasında zor havayolu olarak değerlendirilmiş. MMT sınıf III veya IV olanlar ve UDIT sınıf III olanlar zor entübasyon olarak kabul edilmiş. 300 hastadan MMT sınıf III-IV olan hasta sayısı 108 iken, ÜDIT sınıf III olan hasta sayısı 45 olarak tespit edilmiş. Bu iki sınıflamanın McNemar testiyle özgüllükleri (%95 GA; 66.8 [60.9-72.2]'ye 88.7 [84.3-92])ve doğrulukları (%95 GA; 67.7 [62-72.9]'a 88 [79.9-93.6]) arasında ÜDİT lehine istatistiksel olarak anlamlı fark saptanmış (p0.05).
Dr.Stephanie McNemar- Principal, Colby High School Follow Stephanie's journey @SMcNemar Topics Covered: -Being bold with Change -Filling community needs with your career programming -KESA conversations -Intentional conversations with staff -Involving families in the learning process -What Dr.McNemar is not good at!
In this episode, I talk with my good friend Steve Mcnemar. We talk about how he began coaching softball pitching, how he gets the best out of his players, and how important fishing is in Steve's life. All of his passions connect and he has learned valuable lessons from each. Hope you enjoy! Check out my first published book on Amazon! Symptom Free Neck: Treating Your Neck at Home You can find me on Facebook! Servant PT Podcast Servant PT Instagram servant_pt Check out my new book on Amazon. Link below! Symptom Free Neck: Treating Your Neck at Home Thankful for our sponsor! Please consider visiting our sponsor and donating to help veterans with PTSD. Warrior Horse offers healing and hope to traumatized military veterans by reducing the participating veterans’ symptoms of depression, post-traumatic stress, and suicidal thoughts. Working with horses has long been recognized as an effective tool for helping to treat persons with physical and mental challenges. Warrior Horse offers this program as an adjunct to more long-term forms of assistance that the military veteran may pursue for PTSD and other mental challenges. Warrior Horse’s program will be funded by donations from the general public, donation of race horses by race horse owners, and grants. Donate Now: http://www.warriorhorse.net/donate/ Thank you so much for supporting our podcast! In response to feedback from our loyal listeners, we’d like to graciously offer you even more added value relating to common pains and problems we encounter as physical therapists! Just follow the link below to take advantage of ways that physio can help and save you time, risk-free. We are thrilled to serve you! Follow the link to see the offer! http://vivianphysicaltherapy.com/blog/servant-pt-offer/
Background: To determine if black-blood 3 T cardiovascular magnetic resonance (bb-CMR) can depict differences between symptomatic and asymptomatic carotid atherosclerotic plaques in acute ischemic stroke patients. Methods: In this prospective monocentric observational study 34 patients (24 males; 70 +/- 9.3 years) with symptomatic carotid disease defined as ischemic brain lesions in one internal carotid artery territory on diffusion weighted images underwent a carotid bb-CMR at 3 T with fat-saturated pre- and post-contrast T1w-, PDw-, T2w- and TOF images using surface coils and Parallel Imaging techniques (PAT factor = 2) within 10 days after symptom onset. All patients underwent extensive clinical workup (lab, brain MR, duplex sonography, 24-hour ECG, transesophageal echocardiography) to exclude other causes of ischemic stroke. Prevalence of American Heart Association lesion type VI (AHA-LT6), status of the fibrous cap, presence of hemorrhage/thrombus and area measurements of calcification, necrotic core and hemorrhage were determined in both carotid arteries in consensus by two reviewers who were blinded to clinical information. McNemar and Wilcoxon's signed rank tests were use for statistical comparison. A p-value
Episode 1 of the podcast in which we introduce ourselves and speak of "conferency" things to come with WV Writers President T.W. McNemar. DOWNLOAD (Right click and Save Link Target As) West Virginia Writers Podcast Episode 1
Background: Retention of mouth-to-mouth, mouth-to-mask and mouth-to-face shield ventilation techniques is poorly understood.Methods: A prospective randomised clinical trial was undertaken in January 2004 in 70 candidates randomly assigned to training in mouth-to-mouth, mouth-to-mask or mouth-to-face shield ventilation. Each candidate was trained for 10 min, after which tidal volume, respiratory rate, minute volume, peak airway pressure and the presence or absence of stomach inflation were measured. 58 subjects were reassessed 1 year later and study parameters were recorded again. Data were analysed with ANOVA, textgreekq2 and McNemar tests.Results: Tidal volume, minute volume, peak airway pressure, ventilation rate and stomach inflation rate increased significantly at reassessment with all ventilation techniques compared with the initial assessment. However, at reassessment, mean (SD) tidal volume (960 (446) vs 1008 (366) vs 1402 (302) ml; p
We initially performed a mutation screen of the coding region of the MC4R in 808 extremely obese children and adolescents and 327 underweight or normal-weight controls allowing for a case-control study. A total of 16 different missense, nonsense, and frameshift mutations were found in the obese study group; five of these have not been observed previously. In vitro assays revealed that nine [the haplotype (Y35X; D37V) was counted as one mutation] of the 16 mutations led to impaired cAMP responses, compared with wild-type receptor constructs. In contrast, only one novel missense mutation was detected in the controls, which did not alter receptor function. The association test based on functionally relevant mutations was positive (P = 0.006, Fisher's exact test, one-sided). We proceeded by screening a total of 1040 parents of 520 of the aforementioned obese young index patients to perform transmission disequilibrium tests. The 11 parental carriers of functionally relevant mutations transmitted the mutation in 81.8% (P = 0.033; exact one-sided McNemar test). These results support the hypothesis that these MC4R mutations represent major gene effects for obesity.
Medizinische Fakultät - Digitale Hochschulschriften der LMU - Teil 01/19
Es wurde untersucht, ob in der klinische Routine Information aus axialen CT-Bildern die konventionelle Angiographie ersetzen kann. Die Identifikation hepatischer, perihepatischer sowie abdomineller Gefäße war in der biphasisch kontrastverstärkten Spiral-CT und der DSA unterschiedlich. Die Qualität der Gefäßdarstellung war bei den Arterien in der Angiographie besser als in der Computertomogaphie und dies um so mehr, je kleiner die Gefäße waren. Bei den Venen war die Identifikation der Gefäße in der CT wesentlich besser als in der Angiographie. Für die kleinen intrahepatischen Arterien (A.hepatica dex. und –sin.) und für die großen Venen (V.portae, die V.lienalis und die V.mesenterica sup.) war der Unterschied zwischen Computertomographie und Angiographie nach McNemar signifikant (p