Podcasts about Asymptomatic

Patient is a carrier for a disease or infection but experiences no symptoms

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Asymptomatic

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Best podcasts about Asymptomatic

Latest podcast episodes about Asymptomatic

MeatRx
Is Your Brain Switched On? | Dr. Shawn Baker & Vanessa Spina

MeatRx

Play Episode Listen Later Mar 9, 2025 53:06


Vanessa Spina is a Sport Nutrition Specialist (SNS) and the Best Selling author of Keto Essentials. She is a researcher who studied biomedical science at the University of Toronto, an international speaker and host of the wildly popular Optimal Protein Podcast, ranked in the Top 20 podcasts in the Nutrition category in the USA and globally #1-20. It has been nominated twice as a top 3 Best Podcast at the Metabolic Health Summit.  Vanessa founded Ketogenic Girl in 2015 with online audience of over half a million. Vanessa has created three innovative wellness products. The Tone device, a breath ketone analyzer which measures acetone, the ketone detected on the breath. The second is a new red light therapy line called the Tone LUX Collection. The third is a supplement line called Tone that includes Tone Protein, a protein powder that is scientifically formulated to initiate Muscle Protein Synthesis in every serving with the addition of leucine, and the new Tone Collagen which has clinical studies (RCTs) proving its effectiveness.  She has been featured as a nutrition expert in articles published in the Orlando Sentinel, Eat This, Parade, Reader's Digest and more. Instagram: @ketogenicgirl @optimalproteinpodcast @tonedevice @thetonelux Twitter: @ketogenicgirl Website: Www.ketogenicgirl.com Timestamps: 00:00 Trailer 01:12 Introduction 04:09 Children's innate eating wisdom 07:44 Rising awareness of food quality 10:29 European dietary habits and trends 15:02 Carnivore diet ended my food obsession 17:49 Revamped keto focus on ketones 19:03 Asymptomatic progress and protein satiety 22:26 MCT and ketone supplements for focus 27:36 Ketones: alternative brain fuel 31:53 High-fat foods and nutrition 33:23 Balanced diet preference over carnivore 38:02 Drunken attempt to avoid onions 41:05 New book on high-protein diets 44:28 Whey protein and insulin response 46:23 Whey protein isolate benefits 51:02 Red meat misconceptions persist 52:55 Where to find Vanessa Join Revero now to regain your health: https://revero.com/YT Revero.com is an online medical clinic for treating chronic diseases with this root-cause approach of nutrition therapy. You can get access to medical providers, personalized nutrition therapy, biomarker tracking, lab testing, ongoing clinical care, and daily coaching. You will also learn everything you need with educational videos, hundreds of recipes, and articles to make this easy for you. Join the Revero team (medical providers, etc): https://revero.com/jobs ‪#Revero #ReveroHealth #shawnbaker  #Carnivorediet #MeatHeals #AnimalBased #ZeroCarb #DietCoach  #FatAdapted #Carnivore #sugarfree Disclaimer: The content on this channel is not medical advice. Please consult your healthcare provider.

JACC Podcast
Aortic Valve Replacement vs Clinical Surveillance in Asymptomatic Severe Aortic Stenosis: A Systematic Review and Meta-Analysis | JACC

JACC Podcast

Play Episode Listen Later Mar 3, 2025 72:25


In this episode, Dr. Valentin Fuster summarizes the March 11, 2025 issue of the JACC, which features groundbreaking research on transcatheter aortic valve replacement (TAVR) and its expanding applications. The podcast delves into the latest studies on TAVR's impact on heart failure patients, the need for better patient selection, and how new findings are shaping the future of aortic stenosis treatment.

Mind & Matter
Public Health & Trust in Science in the Post-COVID Era | Martin Kulldorff | 210

Mind & Matter

Play Episode Listen Later Feb 26, 2025 38:03


Send us a textShort Summary: Insider's look at the COVID-19 pandemic response from a seasoned epidemiologist, unraveling myths and lessons with straightforward science.About the guest: Martin Kulldorff, PhD is an epidemiologist and biostatistician with decades of experience in infectious disease monitoring and vaccine safety. He was formerly a professor at Harvard Medical School. Note: Podcast episodes are fully available to paid subscribers on the M&M Substack. Partial versions are available elsewhere. Full transcript and other information on Substack.Episode Summary: Dr. Martin Kulldorff discusses the COVID pandemic response, reflecting on the controversial Great Barrington Declaration, which opposed lockdowns in favor of protecting the vulnerable. They explore the virus's fatality rates, asymptomatic spread, and vaccine efficacy, contrasting textbook epidemiology with real-world decisions. He critiques institutional failures, like the CDC's misleading claims. He shares optimism for future pandemics with better leadership and public awareness.Key Takeaways:Lockdowns ignored basic public health principles, causing collateral damage like missed cancer screenings, while Sweden's focused protection approach led to lower excess mortality.Early data showed COVID's risk was 1000x higher for older people, yet lockdowns didn't prioritize them, unlike textbook strategies.Asymptomatic spread made containment impossible, unlike Ebola, where isolation works due to clear symptoms.Natural immunity was downplayed despite 2500 years of evidence, leading to wasted vaccines on those already immune.CDC falsely claimed vaccines stopped transmission, eroding trust when people got sick anyway, fueling vaccine skepticism.mRNA vaccine boosters lack proper trials, and their long-term effects need rigorous study, not assumptions.Kulldorff's new Journal of the Academy of Public Health pushes open peer review to rebuild trust in science.Related episode:M&M #100: Infectious Disease, Epidemiology, Pandemics, Health Policy, COVID, Politicization Support the showAll episodes, show notes, transcripts, etc. at the M&M Substack Affiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off. Readwise: Organize and share what you read. Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase. KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription. MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off. For all the ways you can support my efforts

Dr. Baliga's Internal Medicine Podcasts
The EVOLVED Trial - Early Intervention in Patients With Asymptomatic Severe Aortic Stenosis and Myocardial Fibrosis

Dr. Baliga's Internal Medicine Podcasts

Play Episode Listen Later Feb 17, 2025 2:23


The EVOLVED trial investigated whether early aortic valve intervention could improve outcomes in asymptomatic patients with severe aortic stenosis and myocardial fibrosis. The randomized, multicenter study of 224 patients found no significant difference in all-cause mortality or unplanned aortic stenosis-related hospitalizations between early intervention and guideline-directed conservative management. However, early intervention was associated with lower rates of NYHA class II-IV symptoms and fewer unplanned hospitalizations. The trial highlights the potential symptomatic benefits of early intervention but underscores the need for further research to assess long-term outcomes.

Dr. Baliga's Internal Medicine Podcasts
Early Intervention in Asymptomatic Aortic Stenosis?

Dr. Baliga's Internal Medicine Podcasts

Play Episode Listen Later Feb 17, 2025 4:47


Recent randomized trials, including EARLY TAVR, AVATAR, RECOVERY, and EVOLVED, suggest benefits of early aortic valve replacement (AVR) in asymptomatic severe aortic stenosis (AS). Early AVR reduces stroke, heart failure hospitalizations, and cardiovascular events, with a trend toward improved survival. The data support shifting from clinical surveillance to early intervention?

CRTonline Podcast
EVOLVED: Early Intervention in Patients with Asymptomatic Severe Aortic Stenosis and Left Ventricular Myocardial Fibrosis

CRTonline Podcast

Play Episode Listen Later Jan 7, 2025 19:00


EVOLVED: Early Intervention in Patients with Asymptomatic Severe Aortic Stenosis and Left Ventricular Myocardial Fibrosis

Emergency Medical Minute
Episode 938: AHA Policy on Management of Elevated Blood Pressure (BP) in the Acute Care Setting

Emergency Medical Minute

Play Episode Listen Later Jan 6, 2025 2:19


Contributor: Aaron Lessen, MD Educational Pearls: Many patients present to the ED with elevated BP Many are referred from outpatient surgery centers or present after an elevated measurement at home Persistent questions on the best way to treat these patients The AHA published a scientific statement on the management of elevated BP in the acute care setting Hypertensive emergencies: SBP/DBP >180/110–120 mm Hg with evidence of new or worsening target-organ damage Includes aortic dissection or subarachnoid hemorrhage  Require aggressive treatment Asymptomatic markedly elevated inpatient BP: SBP/DBP >180/110–120 mm Hg without evidence of new or worsening target-organ damage AND asymptomatic elevated inpatient BP: SBP/DBP ≥130/80 mm Hg without evidence of new or worsening target-organ damage No benefits to urgent treatment in the ED, but there are harms to treating patients in this manner These patients do not require IV medications  Provide reassurance and instructions on following up with their PCP to manage their BP in the outpatient setting Removed the term “hypertensive urgency” References Bress AP, Anderson TS, Flack JM, et al. The Management of Elevated Blood Pressure in the Acute Care Setting: A Scientific Statement From the American Heart Association. Hypertension. 2024;81(8). doi:https://doi.org/10.1161/hyp.0000000000000238 Summarized by Meg Joyce, MS1 | Edited by Meg Joyce & Jorge Chalit, OMS3  Donate: https://emergencymedicalminute.org/donate/  

JAMA Editors' Summary: On research in medicine, science, & clinical practice. For physicians, researchers, & clinicians.
Asthma Inhaled Reliever Therapies, Asymptomatic Aortic Valve Replacement, Review on Peptic Ulcer Disease, and more

JAMA Editors' Summary: On research in medicine, science, & clinical practice. For physicians, researchers, & clinicians.

Play Episode Listen Later Nov 1, 2024 9:27


Editor's Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief, and Preeti Malani, MD, MSJ, Deputy Editor of JAMA, the Journal of the American Medical Association, for articles published from October 26-November 1, 2024.

JournalFeed Podcast
AHA On Asymptomatic HTN | Discharged Severe HTN Outcomes

JournalFeed Podcast

Play Episode Listen Later Oct 26, 2024 12:03


The JournalFeed podcast for the week of Oct 21-25, 2024.These are summaries from just 2 of the 5 articles we cover every week! For access to more, please visit JournalFeed.org for details about becoming a member.Monday Spoon Feed:This article emphasizes the difference between hypertensive emergency and asymptomatic elevated blood pressure (BP). While hypertensive emergency requires prompt treatment to lower BP, treatment of asymptomatic elevated BP in acute care settings may be harmful. Tuesday Spoon Feed: This was a multi-hospital retrospective study of patients who presented to the emergency department with severe hypertension without end organ damage. The authors found that the 1 year rate of major adverse cardiovascular events (MACE) was 15.5%.

Heavy Lies the Helmet
Episode 123 - To Treat or Not to Treat: Hypertension

Heavy Lies the Helmet

Play Episode Listen Later Oct 21, 2024 60:03


It can be difficult to determine whether you should treat undifferentiated hypertension or not. Many clinicians are distracted the number rather than focusing on the patient in front of them. Asymptomatic hypertension, in particular, is often benign. In fact, treating asymptomatic hypertension in a patient who a primary medical history of hypertension can harm them. In this podcast, we discuss these adverse effects related to blood pressure physiology, acute versus chronic hypertension, and how you can determine whether anti-hypertensives or other forms of therapy are indicated. Get CE hours for our podcast episodes HERE! -------------------------------------------- Twitter @heavyhelmet Facebook @heavyliesthehelmet Instagram @heavyliesthehelmet Website heavyliesthehelmet.com Email contact@heavyliesthehelmet.com Disclaimer: The views, information, or opinions expressed on the Heavy Lies the Helmet podcast are solely those of the individuals involved and do not necessarily represent those of their employers and their employees. Heavy Lies the Helmet, LLC is not responsible for the accuracy of any information available for listening on this platform. The primary purpose of this series is to educate and inform, but it is not a substitute for your local laws, medical direction, or sound judgment. --------------------------------------------  Crystals VIP by From The Dust | https://soundcloud.com/ftdmusic Music promoted by https://www.free-stock-music.com

JACC Podcast
Asymptomatic versus symptomatic hypotension with sacubitril/valsartan in heart failure and reduced ejection fraction in PARADIGM-HF

JACC Podcast

Play Episode Listen Later Oct 21, 2024 10:25


In this episode, researchers explore how asymptomatic versus symptomatic hypertension affects heart failure patients on sacubitril valsartan, finding that both types are linked to worse outcomes, but the drug's benefits remain strong, suggesting clinicians should avoid stopping treatment based solely on blood pressure.

Optimize Your Flo
Is It Possible to Have an Asymptomatic Pregnancy? Pregnancy Update Episode 2

Optimize Your Flo

Play Episode Listen Later Sep 27, 2024 27:35


Discover the Secret to Peaceful, Predictable, & PMS Free Periods Here! If you enjoyed today's episode, make sure you leave a rating and review! Want to support the show even more? Grab Berri a Coffee! Mentioned in today's episode: Prenatal Berri's Taking Recommended Website for Pregnancy Support Equipment Berri's Breast Pump Berri's Compression Socks Berri's Pregnancy Support Band Connect with Berri Berri's YouTube Berri's Instagram Berri's TikTok

JACC Speciality Journals
JACC: Advances - Association of Cardiac Troponin T With Coronary Atherosclerosis in Asymptomatic Primary Prevention People With HIV

JACC Speciality Journals

Play Episode Listen Later Sep 17, 2024 3:14


Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances discusses a recently published original research paper on the association of Cardiac Troponin T with coronary atherosclerosis in asymptomatic primary prevention in people with HIV.

WudUpDoe Podcast
Episode 379: Asymptomatic Idiots

WudUpDoe Podcast

Play Episode Listen Later Sep 7, 2024 49:15


Wudupdoe! This week, topics include - Coworker drama - Amazon delivery gone bad - Getting fit - Covid is still around eh? and more

Clinical Chemistry Podcast
The Era of Early Detection and Treatment of Brain Amyloid Deposition in Asymptomatic Individuals?

Clinical Chemistry Podcast

Play Episode Listen Later Aug 29, 2024 16:32


EMiPcast
STD check in Asymptomatic patients

EMiPcast

Play Episode Listen Later Aug 14, 2024 17:36


بیماری‌های منتقل شونده با رابطه‌ی جنسی، در افراد بی‌علامت

National STD Curriculum
Can LGV Be Asymptomatic?

National STD Curriculum

Play Episode Listen Later Aug 12, 2024 12:46 Transcription Available


This episode discusses four recent articles about lymphogranuloma venereum (LGV) including the effectiveness of a 7-day doxycycline course and the increasing prevalence of asymptomatic LGV in the era of HIV PrEP. View episode transcript and references at www.std.uw.edu.This podcast is dedicated to an STD [sexually transmitted disease] review for health care professionals who are interested in remaining up-to-date on the diagnosis, management, and prevention of STDs. Editor and host Dr. Meena Ramchandani is an Assistant Professor of Medicine at the University of Washington (UW) and Program Director of the UW Infectious Diseases Fellowship Program. 

Behind The Knife: The Surgery Podcast
BTK Vascular Surgery Oral Board Review – Sample Episode 3 - Asymptomatic Carotid Stenosis

Behind The Knife: The Surgery Podcast

Play Episode Listen Later Aug 1, 2024 18:28


Our Vascular Surgery Oral Board Audio Review includes 72 high-yield scenarios that cover the majority of the VSCORE topics designed for Vascular Surgeons by Vascular Surgeons.   Scenarios are 5 to 7 minutes long and include a variety of tactics and styles. If you are able to achieve this level of performance in your preparation you are sure to pass the oral exam with flying colors. The second part introduces high-yield commentary to each scenario. This commentary includes tips and tricks to help you dominate the most challenging scenarios in addition to practical, easy-to-understand teaching that covers the most confusing topics we face as vascular surgeons. We are confident you will find this unique, dual format approach a highly effective way to prepare for the test. Learn more about the full set of 72 scenarios here: https://app.behindtheknife.org/course-details/vascular-surgery-oral-board-audio-review Our Vascular Surgery Oral Board Book is available on Amazon here: https://www.amazon.com/dp/B0CZ8ZBF83 Please visit behindtheknife.org to access other high-yield surgical education podcasts, videos and more.  

The Lens Pod
The Lens Newsletter: July 24

The Lens Pod

Play Episode Listen Later Jul 24, 2024 8:50


Too busy to read the Lens? Listen to our weekly summary here! In this week's episode we discuss… Recurrent acute anterior uveitis is associated with Māori ethnicity and HLA-B27 disease, and moderate vision loss is associated with shorter time to first recurrence JAK1 inhibitors may reduce the rate of treatment failure in inflammatory uveitis when compared to patients receiving placebo Asymptomatic vitreoretinal lymphoma (VRL) associated with primary CNS lymphoma exhibits lower rates of anterior segment involvement, vitritis, and subretinal infiltrates when compared to primary vitreoretinal lymphoma and symptomatic vitreoretinal lymphoma associated with primary CNS disease A study identifies patient factors that influence the presence of non-retinal hemorrhage ocular abnormalities in infants

JACC Speciality Journals
JACC: Advances - Serum Lipoproteins Are Associated With Coronary Atherosclerosis in Asymptomatic U.S. Adults Without Traditional Risk Factors

JACC Speciality Journals

Play Episode Listen Later Jul 24, 2024 3:11


SHEA
SHEA Journal Club Spotlight: Key Studies on Antibiotic Therapy & Asymptomatic Bacteriuria

SHEA

Play Episode Listen Later Jun 28, 2024 20:23


In this episode of The SHEA Podcast, SHEA Journal Club Chair and moderator Hannah Imlay is joined by guests Jennifer Cihlar and David Cluck to discuss two of the most impactful articles reviewed by the journal club this year. The first article, "Bacteremia From a Presumed Urinary Source in Hospitalized Adults With Asymptomatic Bacteriuria" by Advani SD, Ratz D, Horowitz JK, et al., examines the clinical implications of asymptomatic bacteriuria in hospitalized adults. The second article, "Identifying Effective Durations of Antibiotic Therapy for the Treatment of Carbapenem-resistant Enterobacterales Bloodstream Infections: A Multicenter Observational Study" by Soto CL, Hsu AJ, Lee JH, et al., explores optimal antibiotic treatment durations for these challenging infections. Join us for an in-depth discussion on the findings and clinical impacts of these studies.

JACC Speciality Journals
JACC: Advances - Coronary Plaque in People With HIV vs Non-HIV Asymptomatic Community and Symptomatic Higher-Risk Populations

JACC Speciality Journals

Play Episode Listen Later Jun 26, 2024 3:03


CanadaPoli - Canadian Politics from a Canadian Point of View

Foreign interference documents meeting pushed, Nude beach disaster, Asymptomatic and surveillance for asymptomatic stuff, What are your feelings on a draft? Hard no from me dawg, Trump talks about bitcoin and cbdc, Invasion of the west is getting big push back, Sign Up for the Full Show Locals (daily video) https://canadapoli2.locals.com/ Spotify https://podcasters.spotify.com/pod/show/canadapoli/subscribe Private Full podcast audio https://canadapoli.com/feed/canadapoliblue/ Buy subscriptions here (daily video and audio podcast): https://canadapoli.com/canadapoli-subscriptions/

JACC Speciality Journals
Cardiac Damage Staging Predicts Outcomes in Symptomatic and Asymptomatic Aortic Stenosis After Aortic Valve Replacement

JACC Speciality Journals

Play Episode Listen Later May 22, 2024 3:33


Wise Traditions
473: Virus FAQs

Wise Traditions

Play Episode Listen Later May 6, 2024 50:26


How can we be sure viruses don't exist? What about the “patient 0” who transmits diseases at the start of nearly every pandemic? And do germs and microorganisms exist? What's making us sick, if not these things? Dr. Samantha and  Dr. Mark Bailey are the authors of “The Final Pandemic” and today they answer frequently asked questions about viruses. They explain how the medical community has been unable to prove that viruses make us sick or that they even exist in the first place. They also answer questions about the use of antibiotics and about whether germ theory and terrain theory can possibly coexist. Visit Sam and Mark's website: drsambailey.com Become a member of the Weston A. Price Foundation Members can get 5 free brochures "Timeless Principles of Healthy Traditional Diets" in private members space here Check out our sponsors: Nutrition Therapy Institute and Polyface Farms Two Days of Truth summit

The Cure
The Bug Stops Here: Asymptomatic Bacteriuria

The Cure

Play Episode Listen Later May 1, 2024 40:52


This episode focuses on a fascinating and often overlooked topic; asymptomatic bacteriuria. This condition, characterized by the presence of bacteria in the urine without symptoms of an infection, poses unique challenges in the field of antimicrobial stewwardship. We'll explore what asymptomatic bacteriuria is, who is most affected, and why it's important to differentiate this condition from symptomatic infections. Our goal is to uncover how understanding and managing asymptomatic bacteriuria can lead to more efffective antibiotic use and ultimately, better patient outcomes. Listen in to learn more.

EMCrit FOAM Feed
EMCrit 373 - Mike Weinstock with another Critical Care Bounceback: "Asymptomatic Hypertension"

EMCrit FOAM Feed

Play Episode Listen Later Apr 18, 2024 57:28


Journal of Clinical Oncology (JCO) Podcast
JCO Article Insights: Low and Moderate Grade Adverse Events and the Patient Experience in Clinical Trials

Journal of Clinical Oncology (JCO) Podcast

Play Episode Listen Later Jan 29, 2024 9:50


In this JCO Article Insights episode, Subodh Selukar summarized findings from the original article published in the January 2024 JCO issue: “The Importance of Low and Moderate Grade Adverse Events on Patients' Treatment Experience and Treatment Discontinuation” and accompanying editorial “Patient Experience, Adverse Event Reporting, and Clinical Trial Design”. The summary provides information regarding low and moderate grade adverse events and the patient experience in clinical trials. TRANSCRIPT Welcome to the JCO Article Insights episode for the January 2024 issue of Journal of Clinical Oncology. This is Subodh Selukar, your host, and today I will be providing a summary on 2 articles focused on low and moderate grade adverse events. The first article, titled “The Importance of Low and Moderate Grade Adverse Events on Patients' Treatment Experience and Treatment Discontinuation” by Dr. O'Connell and colleagues, investigated low and moderate grade adverse events and the patient experience in clinical trials. Their article is accompanied by an editorial entitled “Patient Experience, Adverse Event Reporting, and Clinical Trial Design” by Dr. Neuman.  In clinical trials, a standardized system for reporting adverse events is the Common Terminology Criteria for Adverse Events (or “CTCAE”) established by the NCI, the United States National Cancer Institute. The CTCAE categorizes adverse events at 5 severity grades across 26 system organ classes. However, some clinical trials may only report adverse events at grade 3 or higher, with one possible rationale being that low and moderate grades are unlikely to affect patient safety or key trial endpoints. In Dr. O'Connell's article, the team investigated how the numbers of grade 1 and 2 adverse events related to patient self-reported side-effect burden and treatment discontinuation. To do this, they analyzed data from the Phase 3 trial E1912 conducted by ECOG-ACRIN comparing two treatments for chronic lymphocytic leukemia. They chose this trial as an example because the study data included all adverse event grades throughout the duration of treatment for each patient. The authors studied side-effect burden based on GP5, which is the fifth item in the FACT-G subscale in the Functional Assessment of Cancer Therapy. GP5 rates the patient's agreement with the statement “I am bothered by side effects of treatment” in the past 7 days, and it has previously been connected with adverse event grade and treatment discontinuation. For treatment discontinuation, the authors focused on those discontinuations that were recorded as being due to “adverse events, side effects or complications.” They found that, for each adverse event grade, there were, on average, more adverse events in cycles that ended with a patient discontinuing treatment compared to other cycles. Next, they used Bayesian models to assess how the numbers of grade 1 and grade 2 adverse events in a treatment cycle were associated with the odds of higher side-effect bother and odds of treatment discontinuation, after adjusting for cycle number, treatment and occurrence of grade 3 or higher adverse events within the cycle. Baseline GP5 was also included in the models, and these models also accounted for the inclusion of multiple cycles for each patient. When adjusting for baseline GP5, treatment, cycle and presence of grade 3 or 4 adverse events, both the number of grade 1 and the number of grade 2 adverse events were each strongly associated with increasing side-effect bother. The adjusted odds of treatment discontinuation were also higher with more grade 2 adverse events. However, with the same adjustment variables, the odds of treatment discontinuation were actually lower with larger numbers of grade 1 adverse events. In their primary analysis, they focused on adverse events that were attributed to treatment, so they excluded non-treatment-related adverse events from the counts. Sensitivity analyses including these adverse events have similar conclusions but with a weaker magnitude of effect. They attributed this to issues like existing adverse events not causing new bother. Next, the authors analyzed whether symptomatic versus asymptomatic adverse events affected these results by re-fitting the models and separating the predictors into numbers of asymptomatic and symptomatic grade 1 or 2 adverse events. In these results, they found no evidence for associations between numbers of asymptomatic adverse events at any grade and side-effect bother. On the other hand, they found strong evidence for associations with symptomatic adverse events of grade 2 and 3 or higher both for side-effect bother as an outcome and with treatment discontinuation. Asymptomatic grade 2 adverse events were associated with treatment discontinuation but not side-effect bother, and symptomatic grade 1 adverse events were associated with side-effect bother but not treatment discontinuation.  ·       The authors conclude that adverse events of all grades, especially symptomatic adverse events, should be recorded regularly in cancer clinical trials. Formal patient reported outcomes are not typically collected as frequently as adverse events are recorded, so identifying patients with a high number of lower grade adverse events could be used to facilitate early supportive care to improve patient quality of life and reduce the likelihood for treatment discontinuation. ·       They also highlight their result identifying lower odds of treatment discontinuation with larger numbers of grade 1 adverse events. They provide one explanation that patients may perceive grade 1 adverse events being associated with treatment efficacy, but this perception changes with higher grades.  In their call to collect more lower grade adverse events, the authors acknowledge that recording more adverse events may be time-consuming and burdensome for sites and recommend cost-benefit analyses to develop future guidelines. ·       This balance between the benefits and costs of increased adverse event data collection is the focus of Dr. Neuman's editorial. Dr. Neuman acknowledges that Dr. O'Connell's article provides a convincing argument for how low grade adverse event information is valuable, but notes the clinical trial context that current efforts at the NCI are to more efficiently conduct cancer research, which could be supported by streamlining data collection. ·       Requiring the collection of low grade adverse events could have important impacts to trial logistics. Due to the high volume of low grade adverse events, reporting all low grade events could delay reporting higher grade and more serious adverse events; and it would require an increase in the effort of clinical trial research staff, which would be difficult if not accompanied by an increase in reimbursement to sites. ·       Dr. Neuman suggests 3 approaches to balance the costs and benefits of collecting low and moderate grade adverse events. First, investigators could consider limiting low-grade adverse event reporting to the experimental arm. The standard of care regimens may not always have low-grade adverse event data available, but this may still be justified when there is extensive clinical experience with the standard of care. However, this approach is only practical when the experimental arm is not blinded. ·       A second approach for moderating the effort in collecting low-grade adverse events is to limit collection to symptomatic adverse events, connecting with Dr. O'Connell's example E1912 dataset. This approach could be addressed by prespecifying types of symptomatic adverse events that would be most impactful during the trial design phase. ·       Dr. Neuman's third suggestion is to plan for a follow-up study after the phase 3 trial to collect low-grade adverse event data and their impact on patients' experiences and treatment discontinuation. This would be beneficial by only requiring low-grade adverse events in an experimental regimen that has successfully passed phase 3. However, a new study would require funding and site enthusiasm, which could prove challenging. ·       Overall, Dr. Neuman emphasizes that investigators should develop trial-specific considerations and engage with the relevant stakeholders during study design. Because of the complexity of adverse events in these patient populations, the best uses of grade 1-2 adverse events will likely continue to develop in the future. In their article, Dr. O'Connell's team studied grade 1 and 2 adverse events as separate predictors, but I would be curious to know how the accumulation and trajectory of these adverse events affect the patient experience. For example, even if the severity does not rise to grade 3, an increasing trend in a patient's adverse event severities could signal the treating physician to modify study dose or to discontinue the treatment. I'm not sure if that type of information was available in their trial E1912, but perhaps that could be a factor to consider for the future. And, of course, it will be important to assess how these grade 1-2 adverse events relate to the patient experience in different studies, especially across different cancer patient populations, acknowledging that this is inherently challenging to study because the data to inform this research is not universally available. As Dr. Neuman indicates, trial-specific goals and expertise will remain critical when considering the data collection for a given trial.  That concludes this episode of JCO Article Insights regarding a summary of the article “The Importance of Low and Moderate Grade Adverse Events on Patients' Treatment Experience and Treatment Discontinuation” by Dr. O'Connell and colleagues and the editorial entitled “Patient Experience, Adverse Event Reporting, and Clinical Trial Design” by Dr. Neuman. This is Subodh Selukar. Thank you for your attention and stay tuned for the next episode of JCO Article Insights.

Z & Keith Watched A Movie
Ep 4.50 - Serial Mom (white suburban compartmentalization & asymptomatic lethality)

Z & Keith Watched A Movie

Play Episode Listen Later Dec 16, 2023 71:22


Greetings sports fans! This week we bring you arguably John Waters' most widely viewed film: Serial Mom (1994). Pitch perfect performances really sell this tale of a middle class white lady from the Baltimore 'burbs who erases anyone that gets on her bad side. Plus, per usual, we shit on some of our favorite Hollywood bastards to hate, reference porn and praise Kathy Bates bravura boobies (RIP). Typical. Let's All Go to the Lobby (B.A.N. remix) T.J. Tallie | Asymptomatic Lethality: Cooper, COVID-19, and the Potential for Black Death +++++ Intro: by Professor Ping available on BandcampOutro: Doja Cat performing Paint the Town Red --- Support this podcast: https://podcasters.spotify.com/pod/show/zandkmoviepod/support

Saving Lives: Critical Care w/eddyjoemd
Should We Go Searching for Asymptomatic Catheter-Related Thrombosis?

Saving Lives: Critical Care w/eddyjoemd

Play Episode Listen Later Dec 13, 2023 6:52


The Vasopressor & Inotrope Handbook: Amazon Affiliate Link (I will earn an extra small commission) and Signed Copies. Show Notes: eddyjoemd.com/asymptomatic-catheter-related-thrombosis/ Explore the often-overlooked issue of asymptomatic catheter-related thrombosis (CRT) in ICU patients on The Saving Lives Podcast. This episode delves into a revealing study published in the Annals of Intensive Care, uncovering the incidence, risk factors, and implications of asymptomatic CRT. Join us for a thought-provoking discussion that challenges traditional beliefs and sheds light on crucial aspects of catheter management in critical care. TrueLearn Link: ⁠⁠⁠⁠⁠⁠⁠https://truelearn.referralrock.com/l/EDDYJOEMD25/⁠⁠⁠⁠⁠⁠⁠ Discount code: EDDYJOEMD25 This Podcast was edited using Descript: ⁠⁠⁠⁠https://www.descript.com?lmref=BGOxjQ⁠⁠⁠⁠ Citation: Abbruzzese C, Guzzardella A, Consonni D, Turconi G, Bonetti C, Brioni M, Panigada M, Grasselli G. Incidence of asymptomatic catheter-related thrombosis in intensive care unit patients: a prospective cohort study. Ann Intensive Care. 2023 Oct 19;13(1):106. doi: 10.1186/s13613-023-01206-w. PMID: 37858003; PMCID: PMC10587047. Link to Article --- Support this podcast: https://podcasters.spotify.com/pod/show/eddyjoemd/support

Daily cardiology
Case Discussion 100: Management of asymptomatic congenital anomaly of the right coronary artery

Daily cardiology

Play Episode Listen Later Oct 31, 2023 5:01


Case Discussion 100: Congenital right coronary anomaly

Heart podcast
The assessment and management of asymptomatic atrial fibrillation

Heart podcast

Play Episode Listen Later Oct 24, 2023 15:40


 In this episode of the Heart podcast, Digital Media Editor, Professor James Rudd, is joined by Dr Jason Andrade from the University of British Columbia, Vancouver, Canada. They discuss all aspects of asymptomatic and device-detected atrial fibrillation. If you enjoy the show, please leave us a podcast review at https://itunes.apple.com/gb/podcast/heart-podcast/id445358212?mt=2 or wherever you get your podcasts - it's really helpful. Link to published paper: https://heart.bmj.com/content/early/2023/07/28/heartjnl-2023-322428?rss=1 

The Running Explained Podcast
s3/e37 Bulletproof Your Hips with Dr. Sarah Louie PT, DPT, COMT, FAAOMPT

The Running Explained Podcast

Play Episode Listen Later Oct 5, 2023 65:39


Owwwww my hips hurt! Hip pain in runners is not uncommon, and physical therapist Dr. Sarah Louie joins the show to talk about hips, running, and what you need to know to "bulletproof" your hips as a runner! -What are some misunderstandings runners have about hip injuries? -The form and function of how our hips work -Why you need more than clamshells to bulletproof your hips -Ruling out bone stress injuries -Injuries from morphology differences -Strength training that WORKS for stronger hips -Considerations for pregnant and post-partum runners -Asymptomatic labral tears: what next? -And more! Sarah Louie is a Fellowship Trained Doctor of Physical Therapy and return-to-run coach who specifically helps women runners with hip pain return to run comfortably and confidently through the EmpowHER Hip Program.  https://www.instagram.com/dr.sarah_thehipdoc/

The New American TV
Covid Shot Causes Heart Damage to Asymptomatic Recipients: Study 

The New American TV

Play Episode Listen Later Oct 3, 2023 42:40


A new peer-reviewed study in the journal Radiology suggests that Covid injections cause heart damage even in asymptomatic recipients. The journal's editor emeritus called the concerning findings “compelling” and deserving of further investigation.  Also, a federal court upheld Kentucky and Tennessee's anti child-mutilation laws; an activist journalist who mocked people for being concerned about crime ... The post Covid Shot Causes Heart Damage to Asymptomatic Recipients: Study  appeared first on The New American.

This Week in Virology
TWiV 1028: Asymptomatic SARS-CoV-2 infection and T cells

This Week in Virology

Play Episode Listen Later Jul 23, 2023 115:19


TWiV reviews approvals of the first gene therapy for severe hemophilia A in adults and a monoclonal antibody to prevent RSV respiratory disease in babies and toddlers, and a common allele of HLA that mediates asymptomatic SARS-CoV-2 infection through pre-existing T cell immunity due to previous exposure to common cold coronaviruses. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server First gene therapy for hemophilia A approved (FDA) Luxurna, gene therapy for vision loss (FDA) Anti-RSV monoclonal antibody approved (FDA) Trial of single-dose Nirsevimab (NEJM) Letters read on TWiV 1028 Timestamps by Jolene. Thanks! Weekly Picks Dickson – Phoenix hits 110 degrees for the 19th day in a row, setting national record Brianne – James Webb Telescope One Year Anniversary Photo Kathy – Drone awards photos Alan – WHO Film Festival winners Vincent – Thinking, Fast and Slow by Daniel Kahneman Listener Picks David – The Mass Extinction Debates: A Science Communication Odyssey Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv

Brother Matthew - ChristianCoffeeTime
Discussing The Error Of "Asymptomatic Salvation"

Brother Matthew - ChristianCoffeeTime

Play Episode Listen Later Jul 5, 2023 27:53


Sunday message by Pastor Mat - July 2, 2023 Are there evidences of salvation? Can a person be saved and have zero signs of their salvation? What does the Bible say? Hebrews 6:9-12) "But, beloved, we are persuaded better things of you, and things that accompany salvation, though we thus speak. For God is not unrighteous to forget your work and labour of love, which ye have shewed toward his name, in that ye have ministered to the saints, and do minister. And we desire that every one of you do shew the same diligence to the full assurance of hope unto the end: That ye be not slothful, but followers of them who through faith and patience inherit the promises."  Our website - https://christiancoffeetime.ca/

The Animal Heartbeat
1: Feline cardiomyopathy pt1 - approach to suspected heart disease in asymptomatic cats

The Animal Heartbeat

Play Episode Listen Later Jun 19, 2023 33:15


Join veterinary cardiology specialists, Kieran Borgeat and Jose Novo Matos, in a discussion of feline heart disease. This is the first of a two-part series opening special, covering how to approach heart murmurs in cats, when it may be useful to use blood tests in screening, and how to facilitate performing a heart scan in feline patients.

Primary Care Update
Episode 130: bempedoic acid, polypills and dementia, prophylaxis for STIs, and interpreting asymptomatic CAD

Primary Care Update

Play Episode Listen Later Jun 13, 2023 34:55


This week Kate, Gary, Henry and Mark talk about bempedoic acid for the prevention of ASCVD, the polypill and cognitive decline in the elderly, post-exposure prophylaxis in persons at high risk of STIs, asymptomatic CAD and subsequent AMI risk. And do you know how long ankle arthroplasties last?

AMERICA OUT LOUD PODCAST NETWORK
Asymptomatic Transmission & Other Lies You've Been Told

AMERICA OUT LOUD PODCAST NETWORK

Play Episode Listen Later Jun 3, 2023 58:21


Looking 4 Healing Radio with Dr. Bryan Ardis, Nichola Burnett, Dr. Jana Schmidt, and Dr. Henry Ealy – In this episode of Looking 4 Healing Radio, Dr. Bryan, Nichola, Dr. Jana & Dr. H talk about the history of natural medicine and what blew them away in their research. Listen in as these four Healers talk history, how it has repeated itself with the lie of asymptomatic transmission, and what you can...

JACC Podcast
Prolonged Moderate-Intensity Exercise Does Not Increase Muscle Injury Markers in Symptomatic or Asymptomatic Statin Users

JACC Podcast

Play Episode Listen Later Apr 3, 2023 10:00


Best Science Medicine Podcast - BS without the BS
Episode 536: Asymptomatic bacteriuria in the elderly – Don't drug the bugs?

Best Science Medicine Podcast - BS without the BS

Play Episode Listen Later Mar 17, 2023 29:49


In episode 536, Mike and James talk about 4 questions – Is any bacteriuria associated with altered mental state? – Does treating ASB improve/prevent clinical outcomes? – Does treating ASB improve altered mental state? – Do antibiotic reduction interventions for ASB affect patient outcomes? Tune in to find out the answers. Show Notes 1) Tools […]

Black Op Radio
#1130 – Ray McGinnis, Jim DiEugenio

Black Op Radio

Play Episode Listen Later Jan 20, 2023 138:58


  Ray McGinnis is an author and investigative reporter Book: Unanswered Questions: What the September Eleventh Families Asked and the 9/11 Commission Ignored by Ray McGinnis: Paperback, Kindle Article: Justin Trudeau and the Politics of the Possible: The Emergencies Act Inquiry in Canada and the Triumph of Propaganda by Ray McGinnis How the media covered the early days of the Canadian trucker protest Video: Canadians support Freedom Convoy Video: Freedom Convoy spokesman Benjamin Dichter joins Tucker Carlson to discuss the huge trucker protest The Canadian government had no data to show that truckers were spreading covid-19 Video: Justin Trudeau labels the unvaccinated "extremist, racist, misogynist" Video: Bill Maher on Trudeau: "Now you do sound like Hitler" Covid-19 is less deadlier than flu Video: CDC Director: Vaccines No Longer Prevent You From Spreading COVID The four tests/criteria to declare an emergency CSIS and the top Canadian govt officials The nazi flag-bearer was not investigated and it is still not known who the person was Not a single protestor has ever been charged with assault 119 charges of mischief By noon 14th of Feb, 102 trucks had left voluntarily The govt expanded the meaning of a "threat" There were no weapons in any of the trucks Prime Minister Trudeau lies routinely Government lawyers testified that there was ZERO foreign influence in the trucker protest "The biggest source of fake news is the government followed by the mainstream media" - Jimmy Dore Declassified pfizer document: 5.3.6 Cumulative Analysis Of Post-Authorization Adverse Event Reports Video: Judge Orders Pfizer Vaxx Data Released In 8 Months – NOT 75 Years! (The Jimmy Dore Show) Scientific paper: Curing the pandemic of misinformation on COVID-19 mRNA vaccines through real evidence-based medicine by Aseem Malhotra: Part 1, Part 2 Trudeau testified “I did not call people names” !!! Asymptomatic transmission is a myth Public Order Emergency Commission website: www.publicorderemergencycommission.ca Part B: Jim DiEugenio; beginning at 1:27:00 At Kennedys and King ACTION ALERT: PLEASE ACT ON THIS TODAY! This is an opportunity to free Sirhan Write to the Parole Board supporting Sirhan's parole Address: State of California, Department of Rehabilitation and Correction, Board of Parole, P. O. Box 4036, Sacramento CA 95812-4936 A court case coming up on Gavin Newsom's veto of Sirhan's parole Video: Eloise Boies interviews Oliver Stone and Jim DiEugenio Video: Panel: Oliver Stone, Jim DiEugenio and Paul Bleau at Quebec City (2022) Documentary: Watch Oliver Stone's The Putin Interviews for free: Part 1, Part 2, Part 3, Part 4 Documentary: Ukraine on Fire (2016) (featuring Oliver Stone) Video: Len Osanic interviews the director of Ukraine on Fire Igor Lopatonok Audiobook: Oswald, the CIA and Mexico City (aka The Lopez Report): Listen online, Download MP3s Article: A Narrative is Debunked by Gerry Simone Article: Gus Russo: There is Nothing in those Damn Files! by Jim DiEugenio NBC special Where Were You?: The Day JFK Died was aired on the 50th anniversary in 2013 Please contact Len at osanic@prouty.org if you have/can find the above mentioned documentary Kennedy was getting out of Vietnam at the time of his assassination Listener questions answered Documentary: Rush to Judgement (1967) by Mark Lane FREE Borrowable Ebook: Rush to Judgement (1967) by Mark Lane Who was Oswald talking to in Spanish? Article: Douglas Horne, Inside the ARRB by Jim DiEugenio FREE Borrowable Ebook: Best Evidence by David Lifton Book: Harvey and Lee (2003) (.pdf) by John Armstrong Article: David Lifton Has Passed On by Jim DiEugenio John Armstrong discusses Harvey and Lee in an epic 7-hour interview; download here for just $10 A new 4-hour interview with John Armstrong to be released soon at Bla...

Blood Cancer Talks
Episode 11. ASH22 Recap: Lymphoma and CLL

Blood Cancer Talks

Play Episode Listen Later Dec 21, 2022 39:02


ALPINE Trial: Zanubrutinib vs Ibrutinib in Relapsed/Refractory CLL (https://www.nejm.org/doi/full/10.1056/NEJMoa2211582) CLL2-Give Trial: Updated results Obinutuzumab (G), Ibrutinib (I), and Venetoclax (Ve) triplet in Untreated Patients with CLL with 17p Deletion/TP53 Mutation (https://ash.confex.com/ash/2022/webprogram/Paper163245.html)  AVO Trial: Acalabrutinib, Venetoclax, Obinutuzumab (AVO) in a Population of Previously Untreated Patients with CLL Enriched for High-Risk Disease (https://ash.confex.com/ash/2022/webprogram/Paper168003.html)  Watch-and-Wait RCT in Follicular Lymphoma: Long-term follow-up of Phase 3 Study of Rituximab Versus a Watch and Wait Approach for Patients with Asymptomatic, Low Tumour Burden Follicular Lymphoma (https://ash.confex.com/ash/2022/webprogram/Paper156790.html) Augment Trial: Update of Phase 3 RCT comparing Rituximab-Revlimid (R2) vs Rituximab-Placebo in Relapsed/Refractory Indolent Non-Hodgkin Lymphoma (https://ash.confex.com/ash/2022/webprogram/Paper158631.html) TRIANGLE Study: Ibrutinib Combined with Standard First-Line Treatment or As Substitute for Autologous Stem Cell Transplantation in Younger Patients with Mantle Cell Lymphoma (https://ash.confex.com/ash/2022/webprogram/Paper163018.html) 

Crossland Community Church
Episode 151: A Weary World Rejoices - Week 3 - Asymptomatic - December 18, 2022

Crossland Community Church

Play Episode Listen Later Dec 20, 2022 52:54


A Weary World Rejoices - Week 3 - Asymptomatic - December 18, 2022

Primary Care Update
Episode 117: the plague, treatment of prediabetes, asymptomatic bacteriuria, and the value of pyuria

Primary Care Update

Play Episode Listen Later Nov 27, 2022 30:34


This week, Mark, Kate, Henry and Gary discuss black Friday, black Death; long term outcomes of managing patients with impaired glucose tolerance or "pre-diabetes" (Henry hates that term); treating asymptomatic bacteriuria in nursing home residents; and the significance of microscopic pyuria in asymptomatic patients.

DocTalk with Dr. Adam Nally
Gout: The King's Disease

DocTalk with Dr. Adam Nally

Play Episode Listen Later Nov 22, 2022 18:21


Listen in as Dr. Nally discussed the history of gout, why Hippocrates only thought it happened to royalty and how you can treat and prevent it with a ketogenic or carnivorous lifestyle. Show Note Sources: Kanbara A., Seyama I. Effect of urine pH on uric acid excretion by manipulating food materials. Nucleosides, Nucleotides Nucleic Acids. 2011;30(12):1066–1071. Towiwat P., Li Z.G. The association of vitamin C, alcohol, coffee, tea, milk and yogurt with uric acid and gout. Int J Rheum Dis. 2015;18(5):495–501. Bedir A., Topbas M., Tanyeri F., Alvur M., Arik N. Leptin might be a regulator of serum uric acid concentrations in humans. Jpn Heart J. 2003;44(4):527–536. Garrod AB. The Nature and Treatment of Gout and Rheumatic Gout, 2nd ed, Walton and Maberly, London 1863. Dalbeth N, Phipps-Green A, Frampton C, et al. Relationship between serum urate concentration and clinically evident incident gout: an individual participant data analysis. Ann Rheum Dis 2018; 77:1048. Hall AP, Barry PE, Dawber TR, McNamara PM. Epidemiology of gout and hyperuricemia. A long-term population study. Am J Med 1967; 42:27. Campion EW, Glynn RJ, DeLabry LO. Asymptomatic hyperuricemia. Risks and consequences in the Normative Aging Study. Am J Med 1987; 82:421. Zalokar J, Lellouch J, Claude JR, Kuntz D. Epidemiology of serum uric acid and gout in Frenchmen. J Chronic Dis 1974; 27:59. BRILL JM, MCCARTY DJ. "STUDIES ON THE NATURE OF GOUTY TOPHI" BY MAX FREUDWEILER, 1899. (AN INFLAMMATORY RESPONSE TO INJECTED SODIUM URATE, 1899). AN ABRIDGED TRANSLATION, WITH COMMENTS. Ann Intern Med 1964; 60:486. McCarty DJ, Hollander JL. Identification of urate crystals in gouty synovial fluid. Ann Intern Med 1961; 54:452. Seegmiller JE, Howell RR, Malawista SE. The inflammatory reaction to sodium urate: its possible relationship to the genesis of acute gouty arthritis. JAMA 1962; 180:469. Hutton J, Fatima T, Major TJ, et al. Mediation analysis to understand genetic relationships between habitual coffee intake and gout. Arthritis Res Ther 2018; 20:135. Fanning N, Merriman TR, Dalbeth N, Stamp LK. An association of smoking with serum urate and gout: A health paradox. Semin Arthritis Rheum 2018; 47:825. Lin KC, Lin HY, Chou P. Community based epidemiological study on hyperuricemia and gout in Kin-Hu, Kinmen. J Rheumatol 2000; 27:1045. Zhang Y, Woods R, Chaisson CE, et al. Alcohol consumption as a trigger of recurrent gout attacks. Am J Med 2006; 119:800.e13. Hunter DJ, York M, Chaisson CE, et al. Recent diuretic use and the risk of recurrent gout attacks: the online case-crossover gout study. J Rheumatol 2006; 33:1341. Chhana A, Lee G, Dalbeth N. Factors influencing the crystallization of monosodium urate: a systematic literature review. BMC Musculoskelet Disord 2015; 16:296. Loeb JN. The influence of temperature on the solubility of monosodium urate. Arthritis Rheum 1972; 15:189. Horvath SM, Hollander JL. INTRA-ARTICULAR TEMPERATURE AS A MEASURE OF JOINT REACTION. J Clin Invest 1949; 28:469. Martinon F, Pétrilli V, Mayor A, et al. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 2006; 440:237. Guerne PA, Terkeltaub R, Zuraw B, Lotz M. Inflammatory microcrystals stimulate interleukin-6 production and secretion by human monocytes and synoviocytes. Arthritis Rheum 1989; 32:1443. Terkeltaub R, Zachariae C, Santoro D, et al. Monocyte-derived neutrophil chemotactic factor/interleukin-8 is a potential mediator of crystal-induced inflammation. Arthritis Rheum 1991; 34:894. di Giovine FS, Malawista SE, Thornton E, Duff GW. Urate crystals stimulate production of tumor necrosis factor alpha from human blood monocytes and synovial cells. Cytokine mRNA and protein kinetics, and cellular distribution. J Clin Invest 1991; 87:1375. Guerne PA, Terkeltaub R, Zuraw B, Lotz M. Inflammatory microcrystals stimulate interleukin-6 production and secretion by human monocytes and synoviocytes. Arthritis Rheum 1989; 32:1443.

Straight From The Cutter's Mouth: A Retina Podcast
Episode 368: Journal Club Discussion on Private Equity and Healthcare Expenditures, Pediatric Retinal Detachment, Management of Asymptomatic Retinal Detachments, Gender Trends in Authorship

Straight From The Cutter's Mouth: A Retina Podcast

Play Episode Listen Later Nov 15, 2022


Drs. Ehsan Rahimy, Priya Vakharia, and Yoshihiro Yonekawa join to discuss four recent major journal publications relevant to ophthalmologists.Private Equity and Healthcare Expenditures (https://jamanetwork.com/journals/jama-health-forum/fullarticle/2795946)Pediatric Retinal Detachments (https://www.ophthalmologyretina.org/article/S2468-6530(22)00393-1/fulltext)Asymptomatic Retinal Detachments (https://www.ophthalmologyretina.org/article/S2468-6530(22)00474-2/fulltext)Gender Authorship Trends (https://www.ophthalmologyretina.org/article/S2468-6530(22)00388-8/fulltext)Relevant Financial Disclosures: None relevantYou can now claim CME credits via the AAO website. Visit https://www.aao.org/browse-multimedia?filter=Audi

The Curbsiders Internal Medicine Podcast
#357 Hotcakes: Ultra-short Antibiotics for Pneumonia, Acetazolamide for CHF, Psilocybin for AUD, and Asymptomatic Kidney Stone Removal

The Curbsiders Internal Medicine Podcast

Play Episode Listen Later Sep 28, 2022 40:34


Find out if ultra-short course (two days) antibiotics work for pneumonia, if acetazolamide improves diuretic efficiency in acute decompensated heart failure, should we prescribe psilocybin (magic mushrooms) to treat alcohol use disorder, and if removal of asymptomatic kidney stones decreases the incidence of future events! Time to fill your plate with a fresh stack of hotcakes! Drs. Paul Williams (@PaulNWilliamz), Rahul Ganatra (@rbganatra), and Matt Watto (@doctorwatto) catch up on recent practice-changing articles and guidelines!  Claim free CME for this episode at curbsiders.vcuhealth.org! Episodes | Subscribe | Spotify | Swag! | Top Picks | Mailing List | thecurbsiders@gmail.com | Free CME! Show Segments Intro, disclaimer Ultra-short Antibiotics for Pneumonia,  Acetazolamide for acute heart failure exacerbations,  Psilocybin for AUD, Asymptomatic Kidney Stone Removal Outro Credits Written by: Nora Taranto MD; Rahul Ganatra MD, MPH; Paul Williams, MD, FACP, Matthew Watto MD, FACP Hosted by: Rahul Ganatra MD, MPH; Paul Williams, MD, FACP, Matthew Watto MD, FACP Cover Art: Matthew Watto MD, FACP Reviewer: Rahul Ganatral MD, MPH Technical Production: Pod Paste

The Dr. Tyna Show
Ep. 62: COVID-19: My Final Thoughts - Solo Episode

The Dr. Tyna Show

Play Episode Listen Later Sep 22, 2022 45:16


On this weeks episode, I give you my final thoughts on COVID-19.Topics Discussed:3:11 - Asymptomatic spread and why viruses don't want to kill their hosts9:18 - PCR testing fiasco10:59 - Reports of Covid in the water supply prior to 2020 and people with antibodies to Covid prior to 201912:16 - Social media censorship that I experienced from the beginning15:18 - Why diabetics, males, and smokers were getting hit that hardest from Covid20:51 - I explain ACE receptors & Cytokine storms27:13 - How viruses act inside the obese body36:20 - What we did to our senior citizensDownload my FREE BOOK and get on my email list. Follow me on my Substack BlogSponsored by: The Dr. Tyna StoreGet 10% OFF my Main Store and my CBD Store here.Further Listening:Muscle is MedicineToxic Legacy: Glyphosate, Deuterium and the COVID vaccine Get full access to Dr. Tyna Show Podcast & Censorship-Free Blog at drtyna.substack.com/subscribe

The Highwire with Del Bigtree
AUTHORITIES WERE WRONG ABOUT ASYMPTOMATIC SPREAD

The Highwire with Del Bigtree

Play Episode Listen Later Jun 12, 2022 4:20


The misplaced idea that asymptomatic Covid cases drove viral spread, was the cornerstone of public health authorities enacting draconian mandates and highly destructive lockdowns. Now, data from a new study covering 42 countries shows people with asymptomatic Covid infections are 68% less likely to pass the virus on, highlighting another failure of public health authorities.#AsymptomaticSpread #CovidMisinformation #Fauci #Birx #CDC #FDA #NIH