Podcasts about Metagenomics

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Metagenomics

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Best podcasts about Metagenomics

Latest podcast episodes about Metagenomics

News Headlines in Morse Code at 15 WPM

Morse code transcription: vvv vvv Trump congratulates Canadas Carney as they agree to meet in near future William and Kate celebrate anniversary on Isle of Mull Warning RTS electricity meters in 300,000 homes could stop working Andrea Jenkyns at odds with Nigel Farage on special needs Tony Blair says current net zero push doomed to fail Sycamore Gap tree wedge kept as trophy, court hears Meghan using HRH title but only in private Otley run crossbow attack suspect dies, police confirm Metagenomics test saves womans sight after mystery infection How Spain powered back to life from unprecedented national blackout

News Headlines in Morse Code at 20 WPM

Morse code transcription: vvv vvv Sycamore Gap tree wedge kept as trophy, court hears How Spain powered back to life from unprecedented national blackout Tony Blair says current net zero push doomed to fail Meghan using HRH title but only in private William and Kate celebrate anniversary on Isle of Mull Andrea Jenkyns at odds with Nigel Farage on special needs Otley run crossbow attack suspect dies, police confirm Trump congratulates Canadas Carney as they agree to meet in near future Metagenomics test saves womans sight after mystery infection Warning RTS electricity meters in 300,000 homes could stop working

News Headlines in Morse Code at 25 WPM

Morse code transcription: vvv vvv Meghan using HRH title but only in private Tony Blair says current net zero push doomed to fail William and Kate celebrate anniversary on Isle of Mull How Spain powered back to life from unprecedented national blackout Trump congratulates Canadas Carney as they agree to meet in near future Warning RTS electricity meters in 300,000 homes could stop working Otley run crossbow attack suspect dies, police confirm Andrea Jenkyns at odds with Nigel Farage on special needs Metagenomics test saves womans sight after mystery infection Sycamore Gap tree wedge kept as trophy, court hears

News Headlines in Morse Code at 10 WPM

Morse code transcription: vvv vvv How Spain powered back to life from unprecedented national blackout Warning RTS electricity meters in 300,000 homes could stop working Otley run crossbow attack suspect dies, police confirm Metagenomics test saves womans sight after mystery infection Sycamore Gap tree wedge kept as trophy, court hears Trump congratulates Canadas Carney as they agree to meet in near future Meghan using HRH title but only in private Tony Blair says current net zero push doomed to fail William and Kate celebrate anniversary on Isle of Mull Andrea Jenkyns at odds with Nigel Farage on special needs

Matters Microbial
Matters Microbial #87: Dietary Protein and the Microbiome

Matters Microbial

Play Episode Listen Later Apr 17, 2025 62:32


Matters Microbial #87: Dietary Protein and the Microbiome April 17, 2025 Today, Dr. Manuel Kleiner, Associate Professor of Microbiomes and Complex Microbial Communities at North Carolina State University,  joins the #QualityQuorum to discuss how diet can influence the microbiome in fascinating ways. Host: Mark O. Martin Guest: Manuel Kleiner Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An overview of “pink pigmented facultative methylotrophs,” which can lead to wonderful “leaf prints.” Gnotobiotic versus “germ-free” animals. A solid review of the gut microbiome and the relationship to health. An article describing how proteins are digested by the microbiota. A description of glycan degrading enzymes and the gut microbiome. An overview of mucin. Description of metaproteomics by Dr. Kleiner. Description of metagenomics. Gut microbiota and dysbiosis. An overview of inflammatory bowel disease. An overview of Bacteroides thetaiotaomicron. An overview of Akkermansia muciniphila. The possibility of microbes “farming” us for mucus! The wide ranging and deeply fascinating website for Dr. Kleiner's research group. Dr. Kleiner's faculty website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Matters Microbial
Matters Microbial #84: Detecting Pathogens — and Worse — in Wastewater

Matters Microbial

Play Episode Listen Later Mar 27, 2025 61:30


Matters Microbial #84: Detecting Pathogens — and Worse — in Wastewater March 27, 2025 Today, Dr. Rachel Poretsky, Associate Professor of Biological Sciences at the University of Illinois Chicago joins the #QualityQuorum to discuss how examining wastewater (and related water) can give insights into the presence of pathogen antimicrobial resistance genes and even microbial ecology. Host: Mark O. Martin Guest: Rachel Poretsky Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A link to demonstrate the wonders of the Marine Biological Laboratories' Microbial Diversity course, which I know for a fact is life changing. Recommended by David Ranada, an article about water bottles and microbes.   An essay about the Chicago River and cholera, which led to the necessity of effective waste water treatment. An overview of the complexities of waste water treatment.  Here is a video on that topic.   An essay by Carl Zimmer about the microbial ecology of lakes…and human beings. How “recreational water quality” is determined. An article describing the microbiota associated with human biological waste with an amusing name (scroll down). How qPCR can be used to determine the prevalence of specific microbes. A recent article from Dr. Poretsky's research group, investigating how antimicrobial resistance genes can move through a hospital waste water system. A link to the Bacterial-Viral Bioinformatics Resource Center, for which Dr. Poretsky is a Principle Investigator. The Illinois state wastewater surveillance dashboard.  Fascinating! A Discovery Channel documentary on virus hunting and surveillance that includes Dr. Poretsky. Dr. Poretsky's faculty webpage. Dr. Poretsky's webpage for her research group. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Mind & Matter
Gut Microbiome Plasticity | Peter Turnbaugh | 214

Mind & Matter

Play Episode Listen Later Mar 14, 2025 41:19


Send us a textShort Summary: How diet shapes the gut microbiome and impacts health, with microbiologist Dr. Peter Turnbaugh breaking down the complex science.About the guest: Peter Turnbaugh, PhD is a professor of microbiology and immunology at the University of California, San Francisco, where he leads a lab studying the gut microbiome's role in nutrition and drug response.Note: Podcast episodes are fully available to paid subscribers on the M&M Substack and everyone on YouTube. Partial versions are available elsewhere. Full transcript and other information on Substack.Episode Summary: Nick talks to Peter Turnbaugh discuss the pitfalls of oversimplified diet labels in research, Turnbaugh's studies comparing plant-based and animal-based diets in humans, and how these shifts rapidly alter gut microbes and short-chain fatty acid profiles. Key Takeaways:The term “high-fat diet” in research is often misleading, as it can include high carbs and vary widely, complicating study comparisons.In a 2014 study, switching humans to a plant-based (high-fiber) or animal-based (ketogenic, no-fiber) diet changed their gut microbiome within one day, showing its remarkable adaptability.Ketogenic diets reduce Bifidobacterium in the gut, which may lower inflammation-linked immune cells (Th17), potentially aiding conditions like multiple sclerosis.Short-chain fatty acids (e.g., butyrate) don't just come from fiber; they persist even on zero-fiber ketogenic diets, hinting at alternative microbial pathways.Gut microbes can activate or deactivate drugs, like antibiotics or digoxin, suggesting microbiomes may explain why drugs work differently across individuals.Ketone bodies like BHB alone can mimic some ketogenic diet effects on the microbiome and immunity, simplifying research and hinting at therapeutic potential.Related episode:M&M #203: Metagenomics, Microbiome Transmission, Gut Microbiome in Health & Disease | Nicola Segata*Not medical advice.Support the showAll episodes, show notes, transcripts, etc. at the M&M Substack Affiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off. Readwise: Organize and share what you read. Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase. KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription. MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off. For all the ways you can support my efforts

Notes from a small scientist
Plain language summary: Use of metagenomics for One Health surveillance of environmental AMR in a UK veterinary centre

Notes from a small scientist

Play Episode Listen Later Feb 17, 2025 10:41


In this podcast, I talk about how we used metagenomic sequencing to identify pathogenic species and antimicrobial resistance genes in the environment of a small animal veterinary hospital. All my posts have links to online resources that you might find useful, and ⁠⁠⁠you can find the link to this particular blog here⁠⁠⁠⁠⁠.

JALM Talk Podcast
One Size Fits Small: The Narrow Utility for Plasma Metagenomics

JALM Talk Podcast

Play Episode Listen Later Jan 15, 2025 14:09


Mind & Matter
Metagenomics, Microbiome Transmission, Gut Microbiome in Health & Disease | Nicola Segata | 203

Mind & Matter

Play Episode Listen Later Jan 12, 2025 39:33


Send us a textShort Summary: A deep dive into the enigmatic world of sleep, exploring its biological functions, evolutionary origins, and diverse manifestations across different species.About the Guest: Nicola Segata, PhD is a professor at the University of Trento in Italy.Note: Podcast episodes are fully available to paid subscribers on the M&M Substack and on YouTube. Partial versions are available elsewhere.Episode Summary: Dr. Segata explains metagenomics, the study of genetic material from multiple species, and how it has revolutionized microbiome research; microbiome transmission from mother to child; stability and plasticity of the microbiome throughout life stages; obesity and cancer; influence of diet, lifestyle, and medications like antibiotics on microbiome composition.Key Takeaways:Microbiome Variability: The human microbiome varies significantly between individuals and is influenced by genetics, environment, diet, and lifestyle. Thus, personalized approaches to microbiome health may be necessary.Transmission and Acquisition: Microbes are transmitted vertically from mother to child at birth and horizontally through personal interactions. This transmission can influence health outcomes over one's lifetime.Impact of Diet and Drugs: Diet, particularly coffee consumption, can significantly shape the microbiome, with some bacteria growing in response to specific dietary components. Medications like antibiotics and proton pump inhibitors can also markedly alter microbial communities.Health Implications: The microbiome is linked to various health conditions, from metabolic diseases to cancer, with some treatments like fecal microbiota transplantation showing promise in altering microbiome composition for health benefits.Ancient vs. Modern Microbiomes: Studies on ancient microbiomes, like the Iceman's, suggest that modern urban microbiomes differ from those of our ancestors, potentially impacting modern health issues.Related episodes:M&M #178: Microbiome & Gut-Immune Interactions in Obesity & Metabolic Health | June RSupport the showAll episodes (audio & video), show notes, transcripts, and more at the M&M Substack Affiliates: MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off. Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off. Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase. KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription. Learn all the ways you can support my efforts

Mind & Matter

Subscriber-only episodeSend us a textShort Summary: A deep dive into the enigmatic world of sleep, exploring its biological functions, evolutionary origins, and diverse manifestations across different species.About the Guest: Nicola Segata, PhD is a professor at the University of Trento in Italy.Note: Podcast episodes are fully available to paid subscribers on the M&M Substack and on YouTube. Partial versions are available elsewhere.Episode Summary: Dr. Segata explains metagenomics, the study of genetic material from multiple species, and how it has revolutionized microbiome research; microbiome transmission from mother to child; stability and plasticity of the microbiome throughout life stages; obesity and cancer; influence of diet, lifestyle, and medications like antibiotics on microbiome composition.Key Takeaways:Microbiome Variability: The human microbiome varies significantly between individuals and is influenced by genetics, environment, diet, and lifestyle. Thus, personalized approaches to microbiome health may be necessary.Transmission and Acquisition: Microbes are transmitted vertically from mother to child at birth and horizontally through personal interactions. This transmission can influence health outcomes over one's lifetime.Impact of Diet and Drugs: Diet, particularly coffee consumption, can significantly shape the microbiome, with some bacteria growing in response to specific dietary components. Medications like antibiotics and proton pump inhibitors can also markedly alter microbial communities.Health Implications: The microbiome is linked to various health conditions, from metabolic diseases to cancer, with some treatments like fecal microbiota transplantation showing promise in altering microbiome composition for health benefits.Ancient vs. Modern Microbiomes: Studies on ancient microbiomes, like the Iceman's, suggest that modern urban microbiomes differ from those of our ancestors, potentially impacting modern health issues.Related episodes:M&M #178: Microbiome & Gut-Immune Interactions in Obesity & Metabolic Health | June Round*Not medAll episodes (audio & video), show notes, transcripts, and more at the M&M Substack Affiliates: MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off. Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off. Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase. KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription. Learn all the ways you can support my efforts

Matters Microbial
Matters Microbial #72: Who is in Your Water?

Matters Microbial

Play Episode Listen Later Jan 2, 2025 65:20


Matters Microbial #72: Who is in Your Water? January 2, 2025 Today, Dr. Ameet Pinto, Carlton S. Wilder Associate Professor in Civil and Environmental Engineering at the Georgia Institute of Technology, joins the #QualityQuorum to discuss the microbiome of drinking water and how it can be used to optimize safety and health.  Host: Mark O. Martin Guest: Ameet Pinto Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A short review of a famous article by Dr. Norman Pace about the microbiome of showers and how microbial populations differed due to chlorination. An old discussion of microbial oligotrophy:  the ability to survive on very low levels of nutrients. The story of John Snow, a water fountain, and cholera in England. The concept of “Live/Dead” staining of microbes. An overview of the concept of metagenomics. An article on the microbiome of shower hoses. A public science outreach program to study the microbiome of showerheads. The Instagram link for Dr. Pinto's wonderful cat, Nessie. A great book describing exceptions to Mendelian genetics using cats:  “Cats Are Not Peas.”  Highly recommended. An article about water supplies and the pathogenic microbe Legionella. An overview of water disinfection techniques. An introduction to a model system of a microbial soil community, called THOR by Jo Handelsman and colleagues. Thinking of water treatment and related technologies as a series of ecological niches, via Tom Curtis and Bill Sloane. Dr. Pinto's faculty website. Dr. Pinto's deeply fascinating research group website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Coffee Lit. Rev.
Ep18. Coffee affects your microbiome with Prof. Nicola Segata

Coffee Lit. Rev.

Play Episode Listen Later Dec 3, 2024 41:45


Chris and Doran are joined by Prof. Nicola Segata from University of Trento. Prof. Segata is a world famous professor of computational metagenomics, and is the senior author on a recently published study that strongly suggests that consuming coffee directly affects the population of some gut bacteria. Metagenomics is far removed from our expertise. Instead of us fumbling around the paper, we decided to have the true world expert come talk to us about it. Production note: The paper came out over the holiday period so we recorded remotely. The sound quality is not what we usually strive for, but the content quality is exceptionally high. We hope you enjoy. The paper: Nat. Microbio., 2024, 9, 3120 https://doi.org/10.1038/s41564-024-01858-9 The article can be found in coffee literature library: ⁠⁠https://pages.uoregon.edu/chendon/coffee_literature/coffee_lit_rev/⁠⁠ About Nicola Segata: Prof. Segata is from Trento, matriculated through Trento, spent a brief period as a postdoc at Harvard, and returned to Trento where he holds a position as Professor of Computational Metagenomics. He is one of the most highly cited scientists in all fields and has a staggering career of papers that merge computational biology with amazing experimental datasets. You can find his other works here. Introduction preamble: Friends.

Matters Microbial
Matters Microbial #59: Some (Microbes) Like It Hot—Discussions with the Thermal Biology Institute

Matters Microbial

Play Episode Listen Later Oct 3, 2024 70:09


Matters Microbial #59: Some (Microbes) Like It Hot—Discussions with the Thermal Biology Institute October 3, 2024 Today is an unusual episode of the podcast.  I am visiting four microbiologists in the Thermal Biology Institute at Montana State University of Bozeman, Montana.  They discuss their work exploring the unusual microbes and environments to be found in Yellowstone National Park, ranging from the history of the park to opportunities for undergraduate students, as well as up-to-the-minute research done on the microbial denizens of this microbiological landmark. Host: Mark O. Martin Guests (in order of appearance:): Brent Peyton, Dana Skorupa, Zackary Jay, Anthony Kohtzy Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A history and overview of Yellowstone National Park. An overview of microbiology in Yellowstone National Park. The story of Yellowstone National Park and PCR. Website for the Thermal Biology Institute. A prior podcast of #MattersMicrobial involving Dr. Roland Hatzenpichler and the research done by several of today's guests. Dr. Peyton's faculty website. Dr. Peyton's laboratory website. Dr. Skorupa's faculty website. A great article on the adventurous REU (Research Experience for Undergraduates) that Dr. Skorupa supervises. Dr. Jay's faculty website. A journal article describing some of Dr. Jay's (and Dr. Kohtz') work. A page including Dr. Kohtz An article describing some of Dr. Kohtz' (and Dr. Jay's) work. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

PricePlow
#141: Chad Kerksick - Elite Performance Research & ISSN 2024 Recap (1 of 2)

PricePlow

Play Episode Listen Later Jul 3, 2024 61:28


In Episode 141 of the PricePlow Podcast, Mike and Ben welcome Chad Kerksick, President of the International Society of Sports Nutrition (ISSN), to discuss his journey in exercise science and nutrition research. As a university professor and director of the Exercise and Performance Nutrition Laboratory at Lindenwood University, Chad has tons of experience, insights, and wisdom to share. Chad begins with an overview of his academic and professional background, detailing his roles and responsibilities at Lindenwood University. He discusses the challenges of balancing his busy schedule with his desire to be more active on social media, and it's our goal to bring him out to the media world more often. The conversation then shifts to the opportunities for collaboration between academic labs and the industry, highlighting the value of attending conferences for networking and exploring potential partnerships. Chad shares insights into the types of research his lab conducts, including studies on exercise and nutritional interventions that impact health, performance, and recovery outcomes. Elite research on elite athletes One of the key highlights of the episode is Chad's discussion of a unique case study on elite CrossFit athlete Tia-Clair Toomey. He details the process of collecting blood and stool samples to analyze changes in metabolites and the microbiome during intense training and competition, offering listeners a fascinating glimpse into the complexities of researching elite athletes. Throughout the episode, Chad underscores the power of consistency in diet and exercise, sharing practical advice for maintaining a balanced lifestyle. He also touches on his key research areas, including protein supplementation, probiotics, and resistance exercise, providing valuable insights for both researchers and fitness enthusiasts. This episode is the first of a two-part series aimed at introducing Chad to the PricePlow community and recapping the highlights of the ISSN 2024 conference. The second episode will zero in on a couple of specific ingredients. Chad Kerksick: Elite Performance Research & ISSN 2024 Recap | Episode #141″>https://blog.priceplow.com/podcast/chad-kerksick-issn-141 Video: Watch Chad Kerksick Discuss Research and ISSN 2024 https://www.youtube.com/watch?v=GMuvmSSidXc Show Notes with Chad Kerksick – ISSN, Performance, and More (00:00) – Welcome and Introduction to Chad Kerksick (05:00) – Challenges of a Busy Schedule and Social Media Presence (10:00) – Collaboration Opportunities in Academic Labs (15:00) – Recap of ISSN 2024 Conference (20:00) – Case Study on Tia-Clair Toomey's Fecal Matter (25:00) – Metagenomics and Metabolomics Analysis (30:00) – Shifts in Metabolites During Competition (35:00) – The Power of Consistency in Diet and Exercise (40:00) – Key Research Areas in Exercise Science (45:00) – Challenges and Rewards of Elite Athlete Research (50:00) – Future Research (55:00) – Podcast Wrap-Up, Closing Remarks, and Stay Tuned for Part 2 Where to Find Chad Kerksick Online Instagram: @ChadKerksick LinkedIn: linkedin.com/in/chadkerksick/ ISSN Website: SportsNutritionSociety.org…... Read more on the PricePlow Blog

Neurology Minute
CSF Metagenomics and Host Transcriptomics of Cryptogenic New-onset Refractory Status Epilepticus

Neurology Minute

Play Episode Listen Later Jun 26, 2024 3:48


Dr. Shuvro Roy and Dr. Mary Karalius discuss her paper "CSF Metagenomics and Host Transcriptomics of Cryptogenic New-onset Refractory Status Epilepticus." Show reference: https://www.aan.com/conferences-community/summer-conference/abstracts/

Micro binfie podcast
Kostas Konstantinidis returns to talk to us about ANI and metagenomics

Micro binfie podcast

Play Episode Listen Later Jun 6, 2024 22:07


Kostas Konstantinidis returns to talk to us about ANI and metagenomics by Microbial Bioinformatics

Micro binfie podcast
Kostas Konstantinidis talks to us about ANI and metagenomics

Micro binfie podcast

Play Episode Listen Later May 23, 2024 22:58


We talk with Kostas! For more information please visit https://enve-omics.gatech.edu/

JALM Talk Podcast
Elucidating the Clinical Interpretation and Impact of a Positive Plasma Cell-Free DNA Metagenomics Test Result—A Single Center Retrospective Study

JALM Talk Podcast

Play Episode Listen Later Feb 2, 2024 14:41


The Mushroom Hour Podcast
Ep. 167: Behind the Scenes & Across the Universe with William Padilla-Brown

The Mushroom Hour Podcast

Play Episode Listen Later Jan 9, 2024 54:29


Part 2 of our mind-expanding interview with William Padilla-Brown. This interview was taped after our radio interview (Episode 166) and is even more informal and loose. Hopefully there's some wisdom and new thoughts you can integrate into your reality - take what resonates and leave what doesn't!GUEST:William Padilla-Brown: https://www.instagram.com/mycosymbioteMycosymbiotics: https://mycosymbiotics.com/CRTFD: https://crtfd.com/MENTIONS:https://kajabi.com/https://www.thepermaculturestudent.com/https://www.entheome.org/https://www.cambriangenomics.com/https://en.wikipedia.org/wiki/Nanopore_sequencingMUSHROOM HOUR:https://welcometomushroomhour.comhttps://instagram.com/welcome_to_mushroom_hourhttps://tiktok.com/@welcome_to_mushroom_hourShow Music courtesy of the one and only Chris Peck: https://peckthetowncrier.bandcamp.com/TOPICS COVERED:Mycosymbiotics ProductsLearning Who to TrustCRTFD Sustainable GarmentsUptopia vs. DystopiaWhat is the Future of Cordyceps in the US?Growing Engagement with Soil MicrobiologyNanopore TechnologyPractical Applications of Molecular Biology & Genetic DataMetagenomics & AITime CompressionEthics of Manmade BiologyHuman Origins, Genetic Manipulation, Ancient Teachings7 Generations and Space-Time CollaborationsRemembering our Birthright

Micro binfie podcast
117 From Math to Metagenomics - Titus Brown on Career Journeys and Software Solutions

Micro binfie podcast

Play Episode Listen Later Dec 7, 2023 20:12


In this episode of the Micro Binfie Podcast, Andrew Page and Lee Katz interview Titus Brown about his journey from studying math and physics as an undergrad to becoming a bioinformatician focusing on metagenomics and software development. Topics discussed: Titus' background in math, physics, digital evolution research, and developmental biology His transition into bioinformatics to analyze the influx of genomic data in the 1990s Developing early tools for comparative genomics and sequence analysis The philosophy of creating usable software with good documentation Work on transcriptomics, metagenomics, and k-mers at Michigan State Digital normalization and dealing with large sequencing datasets Moving to UC Davis and continuing work on metagenomics and software like khmer and sourmash Thoughts on challenges around data reuse and accessibility in science. Papers: Spacegraphcats - https://genomebiology.biomedcentral.com/articles/10.1186/s13059-020-02066-4 Sourmash - https://www.biorxiv.org/content/10.1101/2022.01.11.475838v2 IBD exploration - https://dib-lab.github.io/2021-paper-ibd/

This Week in Evolution
TWiEVO 95: Watering the viruses until they bloom

This Week in Evolution

Play Episode Listen Later Nov 14, 2023 61:30


Nels and Vincent discuss how the rewetting of seasonally dried soils, a critical event in Mediterranean grasslands that reactivates dormant soil microorganisms, leading to pulses of carbon and nitrogen mineralization, and is accompanied by a bloom of viral diversity, followed by extensive viral community turnover. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiEVO Links for this episode Join the MicrobeTV Discord server Viral but not bacterial community successional patterns reflect extreme turnover shortly after rewetting dry soils Science Picks Nels - Bluesky Vincent - Cancer Virus Hunters: A History of Tumor Virology Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

The Lab Report
The Best Ways to Test the Microbiome

The Lab Report

Play Episode Listen Later Oct 24, 2023 34:44


When it comes to assessing the microbiome, technology continuously evolves. With that, our understanding of the microbiome deepens. There is a lot of confusion out there regarding technology. Companies use marketing spin to lead you to believe the newest is the best when in fact, every technology has its strengths and weaknesses. No one method can capture the entire dynamic of the microbiome. Here at Genova, we use many methods to give you the most complete look at overall gut health. Today we simplify the science behind laboratory assays used to study the microbiome – culture, qPCR, metagenomics, and transcriptomics. Every method has its advantages and disadvantages. We're cutting through the confusion with no marketing spin, just the facts. Today on The Lab Report: 3:30 So much confusion around laboratory methods - why should we care? 7:45 Culture technology is old but still so important 11:10 Conventional PCR and qPCR (aka Real-Time PCR) 15:40 Beware of these qPCR shortcomings 19:50 Next-Gen Sequencing 21:40 Metagenomics – not all labs are created equally!! 26:55 The vital role of taxonomy libraries 30:30 Transcriptomics and assessing RNA Additional Resources: GI Effects Microbiomix Genova Connect               PROMO CODE:  TheLabReport20 for 20% off Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week's episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don't forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Infinite Machine Learning
Prateek talks about Generative AI in Biology

Infinite Machine Learning

Play Episode Listen Later Oct 16, 2023 27:38


In this episode, the host Prateek Joshi talks about 13 areas in Biology where Generative AI is going to make a big impact: 1. Drug discovery 2. Protein design 3. Synthetic data generation 4. Discovering gene regulatory networks 5. Metagenomics 6. Ecology 7. Drug repurposing 8. Genome assembly 9. Disease prediction and diagnosis 10. Single-cell transcriptonomics 11. Evolutionary biology 12. Protein-Protein interaction 13. Personalized medicine --------Where to find Prateek Joshi: Newsletter: https://prateekjoshi.substack.com Website: https://prateekj.com LinkedIn: https://www.linkedin.com/in/prateek-joshi-91047b19 Twitter: https://twitter.com/prateekvjoshi 

Halteres Presents
Ep. 207: The Ins and Outs of Metagenomics in Diagnostics - Dr. Rick Nolte

Halteres Presents

Play Episode Listen Later Aug 22, 2023 54:35


On this week's episode, Rich Thayer and Mickey Urdea are exploring metagenomics with Dr. Rick Nolte, an engaging expert on the subject. Dr. Nolte helps to define what metagenomics is, its diagnostic uses, its advantages, and where the field is going. This is a delightfully in-depth interview about a complicated but important topic that is very much worth your time; please enjoy. Frederick (Rick) S. Nolte, PhD, is currently a Senior Director/Medical Advisor at Karius, the microbial cell free DNA company, and Professor Emeritus of the Department of Pathology and Laboratory Medicine at the Medical University of South Carolina. He served as Vice-Chair for Laboratory Medicine/Medical Director of Clinical Laboratories and Molecular Pathology. He is a Diplomate of the American Board of Medical Microbiology and a Fellow of the American Academy of Microbiology. Dr. Nolte completed his B.S. degree in Biology at the University of Cincinnati, and his Ph.D. in Medical Microbiology at the Ohio State University. Dr. Nolte completed a postdoctoral fellowship in Public Health and Medical Laboratory Microbiology at the University of Rochester. Prior to coming to MUSC in 2007, he spent 18 years at Emory University School of Medicine where he was a Professor of Pathology and Laboratory Medicine and Director of the Clinical Microbiology, Molecular Diagnostic, and Serology Laboratories at Emory Medical Laboratories. He is active in and held positions of responsibility in the American Society for Microbiology, Association for Molecular Pathology, Clinical and Laboratory Standards Institute, Infectious Diseases Society of America, American Society for Clinical Pathology, College of American Pathology and American Association for Clinical Chemistry. He has authored numerous book chapters, practice guidelines, and peer-reviewed publications in the areas of clinical microbiology and molecular diagnostics.

Columbia University BioWorks
BioWorks 9: Synthetic Biology and Metagenomics Startups with Jeffrey Kim

Columbia University BioWorks

Play Episode Listen Later Aug 12, 2023 46:55


In which Jeffrey Kim, co-founder and CEO of Slingshot Biosciences, discusses how synthetic cell mimics are revolutionizing the way cell-based assays and therapies are performed. He also explains the metagenomics data platform he built at Radiant Genomics and shares his insights on the industry as a scientist, investor, and entrepreneur. Hosted by Kevin Xu.

Smarter Not Harder
Dr. Brad Leech: Advancements in Measuring and Treating the Microbiome

Smarter Not Harder

Play Episode Listen Later May 31, 2023 66:14


In this episode of the Smarter Not Harder Podcast, our guest Dr. Brad Leech joins our host Jodi Duval to give one-cent solutions to life's $64,000 questions that include:   What are the benefits of a healthy microbiome and how do we measure this? What does the gut microbiome do for us, and how does the microbiome interact with systemic health? What are some new advancements surrounding the microbiome in recent years, and what does this mean or change for us clinically? Dr. Brad Leech is a PhD-qualified Clinical Nutritionist specializing in chronic autoimmune conditions and complex gastrointestinal disorders. He provides complete and personalized care to his patients using functional nutrition, integrative medicine and holistic wellness. After entering the profession in 2008, Brad has taught and developed subjects at leading universities and conducted research on intestinal permeability, autoimmune disease management and food-based probiotics. Brad is the Lead Clinical Educator and co-creator of Co-Biome, where his expertise in gastrointestinal healthcare enables him to translate the latest science on the gut microbiome into practical clinical applications. In addition to his research, and working with patients, Brad offers practitioner support through his mentoring program Brad's Brainiacs. What we discuss: [00:00] A healthy microbiome is essential for optimal health and can reduce the risk of chronic diseases [07:40] Diversity in diet is key for a healthy microbiome [14:16] The gut microbiome produces metabolites that impact systemic health [21:10] Microbiome diversity and production of beneficial compounds are linked to various health conditions [27:31] Advanced sequencing methods allow for a comprehensive understanding of the microbiome. [34:21] Metagenomics can identify 28,000 bacterial species and their functions [40:55] Personalized medicine is the new approach to treating dysbiosis [46:54] Reduce LPS-producing bacteria through prebiotic fiber, bovine colostrum, and reducing saturated fats [53:16] Increase butyrate production with resistant starch and diverse fiber [59:41] Recommended daily fiber intake is around 30 grams for females and 38 grams for males Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg   Find out more from Dr. Brad Leech: Website: https://drbradleech.com/ Instagram: @drbradleech Twitter: @drbradleech LinkedIn: https://www.linkedin.com/in/drbradleech/ Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org   Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com   Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.  

The EMJ Podcast: Insights For Healthcare Professionals
Episode 148: The Mysteries of the Maternal Microbiome

The EMJ Podcast: Insights For Healthcare Professionals

Play Episode Listen Later May 12, 2023 39:25


This week, Jonathan is joined by Laura Sycuro, University of Calgary, Alberta, Canada, to explore the microbiome, providing insights into what it means and how it affects mother and child. The pair discuss the interaction between human microbiota and disease, microbial imbalances and how to correct them, and how microbial transmission from mothers impacts the lifelong health of their children. They further dive into the vaginal microbiome and chorioamniotic infection in pre-term labour.   Use the following timestamps to navigate the content discussed in this episode:  (00:00)-Introduction  (02:16)-Research on bobtail squid at the University of Hawaii, USA  (05:48)-Defining the microbiome  (10:56)-Understanding the microbiome  (11:46)-Research into the maternal microbiome, and when bacterial colonisation begins for the infant  (16:42)-Microbiome and the gut–brain axis  (20:00)-Key messages from Sycuro's work investigating genetic and genomic approaches to understanding interaction between human microbiome and disease  (22:58)-The vaginal microbiome in other species  (25:09)-Chorioamniotic infection in pre-term labour  (29:16)-Metagenomics: detecting and assembling genomes of uncultivated species and strains  (32:45)-Emerging areas of research, and Sycuro's personal focus in future  (36:03)-Three wishes for the future of healthcare 

Talking Techniques
Long-read sequencing, metagenomics and the microbiome

Talking Techniques

Play Episode Listen Later May 10, 2023 22:18


In this episode, sponsored by Zymo Research, we explore the microbiome and how long-read sequencing techniques are changing our approach to the field and the exciting discoveries that they have led to. To do this we speak to Kris Locken, Molecular Biologist in the Research & Development department of Zymo Research (CA, USA), and Jeremy Wilkinson, Global Marketing Specialist for Microbial Genomics at PacBio (CA, USA).Find out how microbes compare to nuts and what this means for the challenges of metagenomic sample preparation, how long reads can stack up vs short reads for metagenome assembly and much more, all in this latest episode of Talking TechniquesContents:Intro: 00:00-01:55What is metagenomics and why is it important for microbial studies? 01:55-03:55How has long-read sequencing impacted metagenomics? 03:55-06:05Long-read vs short-read sequencing workflows: 06:05-07:15Addressing barriers to long-read sequencing: 07:15-08:45Sample preparation for long-read sequencing: 08:45-12:20Development of long-read sequencing to improve accuracy and capabilities: 12:20-14:40Best practice for assembly and analysis: 14:40-17:40Exciting examples of the benefits of long-read sequencing: 17:40-20:00What would you wish for to improve the ability long-read sequencing in microbiomics: 20:00-21:40 Hosted on Acast. See acast.com/privacy for more information.

Neurology® Podcast
Metagenomics of Parkinson Disease Implicates the Gut Microbiome in Multiple Disease Mechanisms

Neurology® Podcast

Play Episode Listen Later Dec 15, 2022 16:39


Dr. Jason Crowell talks with Prof. Haydeh Payami, Professor of Neurology and Genetics at the University of Alabama at Birmingham, about how the gut microbiome may play a role in Parkinson disease according to metagenomics. Read the associated article in Nature Communications. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

The Lab Report
Microbiome Metagenomics with Dr. Ken McGrath

The Lab Report

Play Episode Listen Later Dec 6, 2022 56:28


As technology evolves, so too does our understanding of the gut microbiome. Until now, we've only seen the tip of the iceberg. Metagenomics offers us the ability to assess the complete microbiome as well as its potential function. This is the technology that powers Genova's new Microbiomix stool profile and we've partnered with Microba Life Sciences – a world leader in microbiome metagenomic analysis based in Australia. As Microba's Clinical Solutions Manager, Dr. Ken McGrath combines his expertise in molecular genomics with the clinical application of this technology. Today, we speak with an industry-leading expert in microbiome research, Dr. Ken McGrath, who explains all things metagenomics, and what we're now learning (and unlearning) about the gut microbiome. Today on The Lab Report: 3:15 Meet Dr. Ken McGrath 8:15 16s vs. whole genome sequencing metagenomics 16:20 Taxonomy and continually changing organism names 26:20 Microbes vs. Metabolites – total paradigm shift 32:00 Is Dysbiosis even a thing!? 33:45 Parasites, Yeast, and Metagenomics 39:20 Human genomics vs. bacterial genomics 45:30 Global microbiome differences 51:50 The Fireball(s) Additional Resources: Microba Genova's Microbiomix Profile Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week's episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don't forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

ReFi Podcast
Ocean Metagenomics with Courtney and Gordon from New Atlantis DAO

ReFi Podcast

Play Episode Listen Later Nov 8, 2022 57:13


John Ellison and Johnx25bd are joined by Courtney and Gordon for an insightful, exciting and deepening conversation about New Atlantis DAO. The two successful entrepreneurs have founded New Atlantis DAO with the goal of enabling the protection and regeneration of the Ocean. Through pioneering metagenomic data sampling the aim is to create a biodiversity market that will fund the regenerative projects that are sorely needed to secure the World's largest biome and carbon sink. It's an amazing project that is inspiring Scientists to get involved and giving hope to a sector that has been neglected and under funded thus far... Mentioned in the Show: SmartyPants https://www.smartypantsvitamins.com/ Unilever https://www.unilever.com/ Only One https://only.one/ UN https://www.un.org/sustainabledevelopment/oceans/ https://www.globalcitizen.org/en/content/30x30-land-and-ocean-by-2030-explainer/ Kolektivo https://www.kolektivo.network/ 00:00 Intro 03:05 The Problem with the Oceans 04:52 How did you stumble on this? 10:45 Political Landscape/Classes of Protection 13:50 What is the New Atlantis Solution? 19:10 Investor demand 28:00 The call to Contribute 31:46 User Journey/Actors 34:40 Sampling process metagenome explainer 39:46 How do you regenerate the Ocean? 46:10 Scientists reaction to New Atlantis Arrival 49:47 Urgency and Incentive 52:46 Looking Ahead/Get Involved -------------------------------------------- Connect with Courtney & Gordon and get involved with New Atlantis https://discord.com/invite/newatlantis https://mobile.twitter.com/newatlantisdao https://newatlantis.io/ -------------------------------------------- Join the conversation on Twitter, follow: https://twitter.com/ReFiDAOist https://twitter.com/climateXcrypto https://twitter.com/simarsmangat https://twitter.com/johnx25bd Thanks to our friends at Feed Ignite for the podcast and micro-content production: https://feedignite.com --- Send in a voice message: https://anchor.fm/refipodcast/message

Intelligent Design the Future
Michael Behe and Michael Medved Explore Secrets of the Cell

Intelligent Design the Future

Play Episode Listen Later Oct 31, 2022 18:48


On today's ID the Future, Michael Medved interviews biologist Michael Behe about Behe's visually stunning YouTube series, Secrets of the Cell. Behe summarizes one of the key messages of the video series, namely that everything from the life-essential blood clotting system to a myriad of crucial protein structures in our bodies increasingly appear to be far beyond the reach of blind evolutionary mechanisms to build. Instead they appear to be the work of planning and purpose, which is the purview of mind. Meanwhile, even many mainstream evolutionists are growing skeptical of neo-Darwinism, Behe says, as biologists continue to uncover more and more layers of cellular sophistication. The emerging field of metagenomics, he says, is a case in point. Medved also Read More › Source

Inside Matters
Episode 003 - Dr Morgan Langille – microbiome bioinformatics, DNA sequencing, metagenomics

Inside Matters

Play Episode Listen Later Oct 20, 2022 108:12


Dr Morgan Langille, an expert in bioinformatics, talks about developing novel technologies and techniques that enable a better understanding of human-microbial interactions.    Dr Langille discusses advances in the microbiome field as well as combining computer science and microbiology to lead to new therapeutics and diagnostics.   Episode Time Stamps 00:00 Intro 00:30, How Dr Langille got into the field of the microbiome 04:30, Gene duplication and reverse transcription 05:48, What is bioinformatics? 06:34, The evolution of bioinformatics  09:30, Genomic islands 1:04 - Phages 14:30 Dr Langille's first bioinformatics tool  16:00 Bacterial genome libraries  18:20 Extremeophilic bacteria 19:00 Will there be bugs in space 21:42 Bacteria on Mars  22:15 Human microbiome diversity  23:30 Number of human cells vs microbes in the body  25:00 Genomic diversity within the microbiome  28:00 Perfect bioinformatics  33:40 Bioinformatics and microbiome research 34:37 Short read vs long read sequencing  45:30 Shotgun metagenomics  48:00 Bioinformatic tool development  1:01:00 Differences in bioinformatic tools and impact on research  1:06:00 Solutions to current technology challenges in bioinformatics 1:10:06 Tools that Morgan has developed  1:08:05 PICRUSt - bioinformatic tool  1:18:35 Jarvis - bioinformatic tool  1:24:00 Talent wars for bioinformatics  1:26:36 Machine learning and AI 1:32:51 Colorectal cancer and AI  1:36:35 Is blood sterile? 1:38:00 What does the future of medicine look like  1:40:51 DIY FMT  

BioTA Podcast
Metagenomics 2 027

BioTA Podcast

Play Episode Listen Later Oct 17, 2022 25:05


Metagenomics is an approach that is opening new frontiers for biological researchers. This episode is part two of an interview with Dr. Andrew Hasley. In this episode he expands on his description of metagenomics from the previous episode and explains how samples are collected, prepared, sequenced, and the resulting data analyzed.

BioTA Podcast
Metagenomics 1 #026

BioTA Podcast

Play Episode Listen Later Oct 5, 2022 16:25


Metagenomics is a new approach being used to sample environmental DNA to better understand populations and communities of organisms, especially bacterial microbiomes. But what is metagenonimcs, how is it different from other genomic analyses, and how is it done? In part one of a two part episode we interview Dr. Andrew Hasley to learn what metagenomics is and the kind of research questions it can investigate. This episode also welcomes co-host Sarah Sanders to the BioTA podcast.

The Thorne Podcast
Life Finds a Way: The Genetic Map of Microbes

The Thorne Podcast

Play Episode Listen Later Oct 5, 2022 42:48


Dr. Chris Mason, professor at Weill Cornell Medicine, zeroes in on microbial movement within the planetary microbiome, outer space, and even in our own gut systems. Learn more about your “gut print” as well as the scientific possibility of reviving extinct species and lost ecosystems. During this episode you'll learn about: Chris Mason, professor of Genomics, Physiology, and Biophysics at Weill Cornell Medicine and co-founder of Onegevity [00:00:53] Origins of a planetary genetic map [4:51] Metagenomics as a genetic puzzle [6:55] What is the Metropolome? [7:34] The microbial signatures of cities [9:36] How microbes interact with humans [10:45] Using wastewater to study the level of COVID in a population [13:07] Thorne's Gut Health Test with Microbiome Wipe shows which microbes inhabit your gut [15:59] People in our society have less diversity and fewer microbes now than before [18:40] How probiotics can help improve your gut ecosystem [20:03] How epigenetic differences may allow experts to screen patients for cancer [22:07] Questions from the community [26:28] What is the planetary microbiome? [26:35] How do humans fit into the microbiome? [27:51] How genetically similar are humans to one another? [30:55] How can I heal my microbiome? [32:28] What would happen if the Mars Rover brought back a foreign microbe? [34:59] Are there new species of microbes in outer space? [37:06] How can humans embrace the planetary microbiome again? [38:47] How have humans changed the planet's microbiome for better or worse? [40:21] Resources to topics mentioned in this episode: About MetaSUB Understanding How the Gut Acts as a Protective Barrier How the Microbiome Sometimes Helps — And Hurts — the Immune System 8 Facts About the Microbiome and the Microorganisms Living in Your Gut ITOL: Interactive Tree of Life How Does Your Gut Microbiota Develop and Change Throughout Life? Mayo Clinic: Exploring the Connections Between the Microbiome, Health, and Disease Microbiome 101 Links to products mentioned in this episode: Gut Health Test with Microbiome Wipe, Bacillus Coagulans, FloraMend Prime Probiotic®, Prebiotic + Subscribe To More Content Make sure to never miss an episode by subscribing to the show on your podcast app. You can also learn more about what we talked about by visiting Thorne.com and checking out the latest news, videos, and stories on Thorne's Take 5 Daily blog. * These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.                                     Resources to topics mentioned in this episode: About MetaSUB Understanding How the Gut Acts as a Protective Barrier How the Microbiome Sometimes Helps — And Hurts — the Immune System 8 Facts About the Microbiome and the Microorganisms Living in Your Gut ITOL: Interactive Tree of Life How Does Your Gut Microbiota Develop and Change Throughout Life? Mayo Clinic: Exploring the Connections Between the Microbiome, Health, and Disease Microbiome 101 Links to products mentioned in this episode: Gut Health Test with Microbiome Wipe, Bacillus Coagulans, FloraMend Prime Probiotic®, Prebiotic + Subscribe To More Content Make sure to never miss an episode by subscribing to the show on your podcast app. You can also learn more about what we talked about by visiting Thorne.com and checking out the latest news, videos, and stories on Thorne's Take 5 Daily blog. * These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.   More in-depth than the last one since they brought up more questions/ went on more tangents.

Mini Medical School for the Public (Audio)
Peripheral Nerves and Difficult to Diagnose Neurological Diseases

Mini Medical School for the Public (Audio)

Play Episode Listen Later May 27, 2022 56:26


This program discusses peripheral nerve diseases, including the anatomy of the central and peripheral nervous systems by Dr. Maggie Waung. Peripheral nerves control sensory, motor and autonomic functions and can regenerate though very slowly. Dr. Michael Wilson discusses difficult to diagnose neurological disease cases using advances in genomic testing, metagenomics for neuroinfectious disease, cancer and autoantibody detection for inflammatory conditions. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 37858]

Health and Medicine (Video)
Peripheral Nerves and Difficult to Diagnose Neurological Diseases

Health and Medicine (Video)

Play Episode Listen Later May 27, 2022 56:26


This program discusses peripheral nerve diseases, including the anatomy of the central and peripheral nervous systems by Dr. Maggie Waung. Peripheral nerves control sensory, motor and autonomic functions and can regenerate though very slowly. Dr. Michael Wilson discusses difficult to diagnose neurological disease cases using advances in genomic testing, metagenomics for neuroinfectious disease, cancer and autoantibody detection for inflammatory conditions. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 37858]

University of California Audio Podcasts (Audio)
Peripheral Nerves and Difficult to Diagnose Neurological Diseases

University of California Audio Podcasts (Audio)

Play Episode Listen Later May 27, 2022 56:26


This program discusses peripheral nerve diseases, including the anatomy of the central and peripheral nervous systems by Dr. Maggie Waung. Peripheral nerves control sensory, motor and autonomic functions and can regenerate though very slowly. Dr. Michael Wilson discusses difficult to diagnose neurological disease cases using advances in genomic testing, metagenomics for neuroinfectious disease, cancer and autoantibody detection for inflammatory conditions. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 37858]

Health and Medicine (Audio)
Peripheral Nerves and Difficult to Diagnose Neurological Diseases

Health and Medicine (Audio)

Play Episode Listen Later May 27, 2022 56:26


This program discusses peripheral nerve diseases, including the anatomy of the central and peripheral nervous systems by Dr. Maggie Waung. Peripheral nerves control sensory, motor and autonomic functions and can regenerate though very slowly. Dr. Michael Wilson discusses difficult to diagnose neurological disease cases using advances in genomic testing, metagenomics for neuroinfectious disease, cancer and autoantibody detection for inflammatory conditions. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 37858]

The Shape of Work
#205 Aria Hahn & Brianna Blaney on the story behind Pocketed, companies they have helped raise grant funds and challenges they have gone through while scaling their business

The Shape of Work

Play Episode Listen Later Mar 11, 2022 27:29


In this episode, we are joined by two serial entrepreneurs, Brianna Blaney (CEO & Co-Founder) and Dr. Aria Hahn (CTO & Co-Founder) of Pocketed. Pocketed is a platform that simplifies access to grant funding for businesses. It's a free platform through which businesses automatically match with different funding programs they're eligible for. It also provides funding management solutions for businesses where they act as their agents.Brianna has successfully scaled an HR and recruitment services company across Canada called Envol Solutions Inc. including securing grants for clients with annual revenue over $1M. With a PhD in Metagenomics and Bioinformatics, Aria is experienced in developing algorithms and data solutions for complex problems. She successfully built a bioinformatics service company, Koonkie Cloud Services. Brianna and Aria have a shared passion for developing scalable businesses and powering economic growth. Read on for our favourite highlights and top takeaways from the conversation.The story behind ‘Pocketed' and its nameCompanies that have raised grant funding through the platformSome challenges that they have gone through and their learningsInspirations that have helped push through tough timesTheir vision for a Pocketed-enabled world as they continue to expand and growAdvice for budding entrepreneurs, founders, and business ownersFollow Brianna and Aria on LinkedInProduced by: Priya BhattPodcast host: Moshe VhanunuAbout Springworks:Springworks is a fully-distributed HR technology organization that is building tools and products to simplify recruitment, on-boarding, employee engagement, and retention. The product stack from Springworks includes:SpringVerify — B2B verification platformEngageWith — employee recognition and rewards platform that enriches company cultureTrivia — a suite of real-time, fun, and interactive games platforms for remote/hybrid team-buildingSpringRole — verified professional-profile platform backed by blockchain, andSpringRecruit — a forever-free applicant tracking system.Springworks prides itself on being an organization focused on employee well-being and workplace culture leading to a 4.8 rating on Glassdoor for the 200+ employee strength company

The Perfect Stool Understanding and Healing the Gut Microbiome
Metagenomic Gut Sequencing with Dr. Robin Rose

The Perfect Stool Understanding and Healing the Gut Microbiome

Play Episode Listen Later Sep 1, 2021 69:40


Thinking of ordering a full genome gut sequencing test? Robin Rose, DO, a double board-certified specialist in Gastroenterology and Internal Medicine takes us through a BiomeFX test, Microbiome Lab's metagenomic gut microbiome test, explaining what each section means for your gut health, and finishes with her treatment plan for the sample report we examine. Learn about how Dr. Rose approaches gut dysbiosis with enzymes, probiotics, prebiotics and binders, rather than the traditional antimicrobial route. Lindsey Parsons, your host, helps clients solve gut issues and reverse autoimmune disease naturally. She's a Certified Health Coach at High Desert Health in Tucson, Arizona. She coaches clients locally and nationwide. You can also follow Lindsey on Facebook, Twitter, Instagram or Pinterest or reach her via email at lindsey@highdeserthealthcoaching.com to set up a free 30-minute Gut Healing Breakthrough Session. Show Notes

Illumina Genomics Podcast
Metagenomics in the time of Covid-19: Emerging Pathogens

Illumina Genomics Podcast

Play Episode Listen Later Apr 1, 2021 19:10


The Bioinformatics and Beyond Podcast
Matthew Schechter: Metagenomics History Part 2

The Bioinformatics and Beyond Podcast

Play Episode Listen Later Feb 27, 2021 22:40


In this second part of our history of metagenomics with Matthew Schechter, we start with a description of what a metagenome contains and how you analyze this type of data. Matt explains a few high level concepts such as metagenome assembly, metagenomic assembled genomes, contigs, contig binning, and genome completeness. Matt explains how metagenomics can help answer previously unanswered questions and even generate new hypotheses like in the example of the Candidate Phyla Radiation. Matt further explains how metagenomics is unbiased when compared to 16S sequencing and what his vision is for “Metagenomics 3.0.” Further topics discussed include pangenomics, further ways metagenomics can generate new hypotheses, and metapangenomics. Read Matt's full article of the history of metagenomics at https://merenlab.org/2020/07/27/history-of-metagenomics/

The Bioinformatics and Beyond Podcast
Matthew Schechter: Metagenomics History Part 1

The Bioinformatics and Beyond Podcast

Play Episode Listen Later Feb 20, 2021 28:33


In this episode we begin our history of metagenomics with Matthew Schechter. Beginning with highlights like the initial ability to see microbes with a microscope and growing microbial colonies, we work our way through the history of metagenomics leading to modern day sequencing. Matt describes a discrepancy between culturing and what is present in a sample, and how sequencing began to overcome this discrepancy. Matt covers what 16S sequencing is and where it fits in the history of metagenomics. We end with a discussion of a seminal work on reconstructing genomes from sequenced metagenomes. Read Matt's full article of the history of metagenomics at https://merenlab.org/2020/07/27/history-of-metagenomics/

The Bioinformatics and Beyond Podcast
Dr. Krista Ternus: Metagenomics, Biosecurity, and Clinical Applications; "What's in my sample?"

The Bioinformatics and Beyond Podcast

Play Episode Listen Later Oct 10, 2020 16:38


Dr. Krista Ternus explains how studying metagenomics leads to being able to answer what is in an unknown sample, and describes the multiple applications of metagenomics. Dr. Ternus also explains applications of bioinformatics in synthetic biology and biosecurity.

The LabAroma Podcast by Colleen Quinn
023 Eric J Mathur- The Future Science Of Our Plant World

The LabAroma Podcast by Colleen Quinn

Play Episode Listen Later Oct 15, 2019 48:38


Eric Mathur currently serves Chief Science Officer for TILT Holdings where he oversees the Company's efforts on Cannabis molecular breeding program for the development of pure-line hybrid cultivars with defined chemical profiles tailored for specific therapeutic medical applications. His expertise and knowledge traverses' genome sciences, molecular biology, environmental microbiology, plant-microbe interactions, metagenomics, enzyme & drug discovery, plant domestication and applied biotechnology. Mathur's career spans over 35 years in basic and applied biotechnology with focus on translational science. Eric entered the San Diego biotechnology arena early, in 1983 as founder of Stratagene, where he discovered and commercialized Pfu DNA polymerase, which is still a mainstay enzyme used in the PCR industry. After a nine years' tenure, Mathur was recruited to become the first employee of Diversa Corporation, which later achieved the largest biotech IPO of the time, raising $200MM in 2001. At Diversa, Eric managed a large scientific team and multiple corporate collaborations with industrial partners including Syngenta, Dow Chemical and BASF. Following 14 years with Diversa, Mathur was recruited to start Craig Venter's company, Synthetic Genomics where he led research efforts in microbial enhanced hydrocarbon recovery sponsored by BP; he also spearheaded the genome sequencing and annotation the oil palm genome for Genting Berhad; and established a platform for plant growth promoting bacteria which led to the spinout, Agradis and subsequent Monsanto acquisition. Eric's interests then turned to plant genomics and crop domestication; he worked as Chief Science Officer for several companies including Yulex Corporation and SG Biofuels, GreenKiss NY and Cultivation.Technologies Inc., where he applied modern genomic tools and plant molecular breeding methods to accelerate plant productivity. The work culminated in dramatic yield improvements in two sustainable crops, Guayule for natural rubber production and Jatropha for biodiesel. Eric Mathur is an internationally recognized speaker who authored over 50 peer-reviewed publications and is named inventor on 100+ issued patents. Eric's passion lies in leveraging genome-based technologies to develop nutrient dense foods and therapeutic medicinals; Mathur is also an ardent supporter of sustainable agricultural and does his part to help secure global food & energy security, while minimizing the impact on our fragile environment.Find and Learn from at the following linkshttps://www.slideshare.net/slideshow/embed_code/key/8u788aek8BVDwWhttps://www.slideshare.net/slideshow/embed_code/key/zoKogkEVxdBb13To learn more about plants & your health from Colleen at LabAroma check out this informative PDF: https://mailchi.mp/2fe0e426b244/osw1lg2dkh