Podcasts about excimer

How has Laser Atherectomy advanced over the years to treat patients with coronary and peripheral artery disease? Dr. On Topaz, renowned specialist in laser atherectomy, answers exactly that and much more in this week's episode the BackTable Podcast. Dr. Topaz is an interventional cardiologist and a professor of medicine at Duke University. --- CHECK OUT OUR SPONSOR AngioDynamics Auryon System https://www.auryon-system.com/ --- SYNPOSIS The doctors begin their discussion by comparing traditional Excimer laser and new Auryon laser technologies. The conversation also covers thrombus management, use of lasers in complex plaques, the latest research studies on laser atherectomy, and future developments in laser technology for varied medical applications. --- TIMESTAMPS 00:00 - Introduction 10:01 - Laser Atherectomy & Thrombus Management 21:59 - Laser Applications in Peripheral Arterial Disease 28:12 - Laser in Interventional Cardiology 41:17 - New Laser Technologies 47:50 - Research Findings and Clinical Trials 59:09 - Future Prospects and Applications --- RESOURCES Book by Dr. On Topaz - Debulking in Cardiovascular Interventions and Revascularization Strategies: https://www.sciencedirect.com/book/9780128214510/debulking-in-cardiovascular-interventions-and-revascularization-strategies Book by Dr. On Topaz - Lasers in Cardiovascular Interventions: https://link.springer.com/content/pdf/10.1007/978-1-4471-5220-0.pdf Book by Dr. On Topaz - Cardiovascular Thrombus: From Pathology and Clinical Presentations to Imaging, Pharmacotherapy and Interventions: https://www.sciencedirect.com/book/9780128126158/cardiovascular-thrombus Paper from Dr. Giancarlo Biamino - The excimer laser: science fiction fantasy or practical tool?: https://pubmed.ncbi.nlm.nih.gov/15760264/ Clinical Trial from Dr. John Bittl - Predictors of outcome of percutaneous excimer laser coronary angioplasty of saphenous vein bypass graft lesions. The Percutaneous Excimer Laser Coronary Angioplasty Registry: https://pubmed.ncbi.nlm.nih.gov/8023778/ Paper from Dr. Warren S. Grundfest - https://journals.lww.com/coronary-artery/citation/1990/07000/laser_angioplasty.4.aspx Paper from Dr. George S. Abela - Abrupt Closure After Pulsed Laser Angioplasty: Spasm or A “Mille-Feuilles” Effect?: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1540-8183.1992.tb00830.x Solid state, pulsed-wave 355 nm UV laser atherectomy debulking in the treatment of infrainguinal peripheral arterial disease: The Pathfinder Registry: https://pubmed.ncbi.nlm.nih.gov/38566525/

Dr. Marc Odrich is Chief Medical Officer at LENZ therapeutics and has decades of experience in private practice, teaching, and medical research that contributes to LENZ Therapeutics success by driving the clinical trial and approval of our novel products. His expertise in authoring and directing over 25 clinical trials throughout his career makes him uniquely qualified to execute the approval process. In addition to his duties as Chief Medical Officer, Dr. Odrich is an Associate Professor of Ophthalmology at the University of Virginia, where he practices and teaches Clinical Ophthalmology specializing in Refractive Surgery and Ocular Surface Disease. He is also the Chief Medical Officer for TearSolutions, Inc., a startup in clinical trials for a new drug developed for dry eye disease. In addition, he is a consultant and member of the Board of Directors for CXLO, Inc., a developer of an innovative treatment for keratoconus and other corneal ectasias, as well as a consultant and medical monitor for Johnson & Johnson's refractive products. Previously, he played pivotal roles in the development and commercialization of the Excimer and Femto lasers as Medical Director at Visx. Dr. Odrich is a graduate of Columbia College and received his medical degree from Columbia University College of Physicians and Surgeons. He completed an internship in internal medicine at Yale's Danbury Hospital before moving to pursue his residency at Columbia's Harkness Eye Institute. Odrich then completed a two-year fellowship focused on cornea and external disease at Harvard's Massachusetts Eye and Ear Infirmary.

I read from exchange to excitable.     The chess board thing makes sense! Exchequer "...refers to a cloth divided in squares that covered a table...and which reminded people of a chess board." https://www.etymonline.com/word/exchequer#etymonline_v_14027     The word of the episode is "excimer laser". https://en.wikipedia.org/wiki/Excimer_laser     Theme music from Tom Maslowski https://zestysol.com/     Merchandising! https://www.teepublic.com/user/spejampar     "The Dictionary - Letter A" on YouTube   "The Dictionary - Letter B" on YouTube   "The Dictionary - Letter C" on YouTube   "The Dictionary - Letter D" on YouTube   "The Dictionary - Letter E" on YouTube     Featured in a Top 10 Dictionary Podcasts list! https://blog.feedspot.com/dictionary_podcasts/     Backwards Talking on YouTube: https://www.youtube.com/playlist?list=PLmIujMwEDbgZUexyR90jaTEEVmAYcCzuq     https://linktr.ee/spejampar dictionarypod@gmail.com https://www.facebook.com/thedictionarypod/ https://www.threads.net/@dictionarypod https://twitter.com/dictionarypod https://www.instagram.com/dictionarypod/ https://www.patreon.com/spejampar https://www.tiktok.com/@spejampar 917-727-5757

Professor Gus Gazzard is joined by Ahmad Elsahn to delve into the use of excimer laser technology and its impact in shifting mindsets towards more interventional strategies for glaucoma patients. They provide insights into the distinct characteristics of the excimer laser, and discuss the safety and efficacy of the treatment.

Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: Far-UVC Light Update: No, LEDs are not around the corner (tweetstorm), published by Davidmanheim on November 2, 2022 on LessWrong. I wrote a tweetstorm on why 222nm LEDs are not around the corner, and given that there has been some discussion related to this on Lesswrong, I thought it was worth reposting here.People interested in reducing biorisk seem to be super excited about 222nm light to kill pathogens. I'm also really excited - but it's (unfortunately) probably a decade or more away from widespread usage. Let me explain. Before I begin, caveat lector: I'm not an expert in this area, and this is just the outcome of my initial review and outreach to experts. And I'd be thrilled for someone to convince me I'm too pessimistic. But I see two and a half problems. First, to deploy safe 222nm lights, we need safety trials. These will take time. This isn't just about regulatory approval - we can't put these in place without understanding a number of unclear safety issues, especially for about higher output / stronger 222nm lights. We can and should accelerate the research, but trials and regulatory approval are both slow. We don't know about impacts of daily exposure over the long term, or on small children, etc. This will take time - and while we wait, we run into a second problem; the Far-UVC lamps. Current lamps are KrCl “excimer” lamps, which are only a few percent efficient - and so to put out much Far-UVC light, they get very hot. This pretty severely limits their use, and means we need many of them for even moderately large spaces. They also emit a somewhat broad spectrum - part of which needs to be filtered out to be safe -/ - further reducing efficiency. Low efficiency, very hot lamps all over the place doesn't sound so feasible. So people seem skeptical that we can cover large areas with these lamps. The obvious next step, then, is to get a better light source. Instead of excimer lamps, we could use LEDs! Except, of course, that we don't currently have LEDs that output 222nm light. (That's not quite true - there are some research labs that have made prototypes, but they are even less efficient than Excimer lamps, so they aren't commercially available or anywhere near commercially viable yet, as I'll explain.) But first, some physics! The wavelength of light emitted by an LED is a material property of the semiconductor used. Each semiconductor has a band-gap which corresponds to the wavelength of light LEDs emit. It seems likely that anything in the range of between, say, 205-225nm would be fine for skin-safe Far-UVC LEDs. So we need a band-gap of somewhere around 5.5 to 6 electron-volts. And we have options. Here's a list of some semiconductors and band-gaps;. Blue LEDs use Gallium nitride, with a band-gap of 3.4 eV. Figuring out how to grow and then use Gallium nitride for LEDs won the discoverers a Nobel Prize - so finding how to make new LEDs will probably also be hard. Aluminum nitride alone has a band gap of 6.015 eV, with light emitted at 210nm. So Aluminum nitride would be perfect. but LEDs from AlN are mediocre./ Current tech that does pretty well for Far-UVC LEDs uses AlGaN; Aluminium gallium nitride. And when alloyed, AlGaN gives an adjustable band-gap, depending on how much aluminum there is. Unfortunately, aluminum gallium nitride alloys only seem to work well down to about 250nm, a bunch higher than 222nm. This needs to get much better. Some experts said a 5-10x improvement is likely, but it will take years. That's also not really enough for the best case, universal usage of really cheap disinfecting LEDs all around the world. It also might not get much better, and we'll be stuck with very low efficiency Far-UVC LEDs, at which point it's probably better to keep using Excimer lamps. But fundamental research into other semiconductor materials could a...

Link to original articleWelcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: Far-UVC Light Update: No, LEDs are not around the corner (tweetstorm), published by Davidmanheim on November 2, 2022 on LessWrong. I wrote a tweetstorm on why 222nm LEDs are not around the corner, and given that there has been some discussion related to this on Lesswrong, I thought it was worth reposting here.People interested in reducing biorisk seem to be super excited about 222nm light to kill pathogens. I'm also really excited - but it's (unfortunately) probably a decade or more away from widespread usage. Let me explain. Before I begin, caveat lector: I'm not an expert in this area, and this is just the outcome of my initial review and outreach to experts. And I'd be thrilled for someone to convince me I'm too pessimistic. But I see two and a half problems. First, to deploy safe 222nm lights, we need safety trials. These will take time. This isn't just about regulatory approval - we can't put these in place without understanding a number of unclear safety issues, especially for about higher output / stronger 222nm lights. We can and should accelerate the research, but trials and regulatory approval are both slow. We don't know about impacts of daily exposure over the long term, or on small children, etc. This will take time - and while we wait, we run into a second problem; the Far-UVC lamps. Current lamps are KrCl “excimer” lamps, which are only a few percent efficient - and so to put out much Far-UVC light, they get very hot. This pretty severely limits their use, and means we need many of them for even moderately large spaces. They also emit a somewhat broad spectrum - part of which needs to be filtered out to be safe -/ - further reducing efficiency. Low efficiency, very hot lamps all over the place doesn't sound so feasible. So people seem skeptical that we can cover large areas with these lamps. The obvious next step, then, is to get a better light source. Instead of excimer lamps, we could use LEDs! Except, of course, that we don't currently have LEDs that output 222nm light. (That's not quite true - there are some research labs that have made prototypes, but they are even less efficient than Excimer lamps, so they aren't commercially available or anywhere near commercially viable yet, as I'll explain.) But first, some physics! The wavelength of light emitted by an LED is a material property of the semiconductor used. Each semiconductor has a band-gap which corresponds to the wavelength of light LEDs emit. It seems likely that anything in the range of between, say, 205-225nm would be fine for skin-safe Far-UVC LEDs. So we need a band-gap of somewhere around 5.5 to 6 electron-volts. And we have options. Here's a list of some semiconductors and band-gaps;. Blue LEDs use Gallium nitride, with a band-gap of 3.4 eV. Figuring out how to grow and then use Gallium nitride for LEDs won the discoverers a Nobel Prize - so finding how to make new LEDs will probably also be hard. Aluminum nitride alone has a band gap of 6.015 eV, with light emitted at 210nm. So Aluminum nitride would be perfect. but LEDs from AlN are mediocre./ Current tech that does pretty well for Far-UVC LEDs uses AlGaN; Aluminium gallium nitride. And when alloyed, AlGaN gives an adjustable band-gap, depending on how much aluminum there is. Unfortunately, aluminum gallium nitride alloys only seem to work well down to about 250nm, a bunch higher than 222nm. This needs to get much better. Some experts said a 5-10x improvement is likely, but it will take years. That's also not really enough for the best case, universal usage of really cheap disinfecting LEDs all around the world. It also might not get much better, and we'll be stuck with very low efficiency Far-UVC LEDs, at which point it's probably better to keep using Excimer lamps. But fundamental research into other semiconductor materials could a...

Biostats with Phil Watkins – SPD recap – Terbinafine okay in liver disease – Morphea: A systemic disease? – Excimer for AA Connect with us! - Web: https://dermaspherepodcast.com/ - Twitter: @DermaspherePC - Instagram: dermaspherepodcast - Facebook: https://www.facebook.com/DermaspherePodcast/ - Check out Luke and Michelle's other podcast, SkinCast! https://healthcare.utah.edu/dermatology/skincast/ Luke and Michelle report no significant conflicts of interest… BUT check out our friends at: Kikoxp.com (a social platform for doctors to share knowledge) https://www.levelex.com/games/top-derm (A free dermatology game to learn more dermatology!)

11. prikázanie - Neposolíš. Studené pivo a slané arašidy? Pozor na to, keď máte nábeh na pankreatitídu. Gastroenterológ, MUDr. Radovan Juríček. NEXT? MANIPULATORIS DEMENTORIS  https://open.spotify.com/episode/4j1KPPeLfXa1kBBpmrI7AJ  Ak laserová operácia očí, tak EXCIMER  https://www.excimer.sk/  Staň sa Dobrým anjelom. Vyskúšaj si, aký je to pocit  https://dobryanjel.sk/stante-sa-dobrym-anjelom/  Doktora Fatrsíka a brata Filipa ti prináša sieť nemocníc SVET ZDRAVIA. Produkcia by ZAPO  https://www.zabavavpodcastoch.sk/reklama/  Mikiny, hrnčeky, tričká a rúška Doktor má Filipa objednávaj tu  https://www.zabavavpodcastoch.sk/kategoria-produktov/doktor-ma-filipa/  

Si tienes miopía, hipermetropía o astigmatismo, probablemente hayas valorado la posibilidad de operarte para poder prescindir de las gafas o de las lentes de contacto. Nos detenernos en la CIRUGÍA REFRACTIVA CON LÁSER EXCIMER; cirugía ambulatoria que la mayoría de los pacientes operados definen como sencilla, rápida e indolora. ¿Podemos operarnos ambos ojos a la vez? ¿Cuánto tiempo se tarda en poder reanudar una actividad normal? ¿En qué casos estaría contraindicada? Preguntas que trasladamos al Dr. Giacomo de Benedetti, jefe del servicio de Oftalmología de Asunción Klinika, con nueva consulta en el Centro Médico Arrasate (Calle Arrasate, 53, Donostia).

Bald movie villains - Excimer for notalgia paresthetica - Chopin > injection pain - Doxy for necrobiosis lipoidica - Emerging contact allergens: Medicines and medical devices - Pior auths suck, and now we know how much For more information on Luke's Practical Dermatology for Primary Care course: https://medicine.utah.edu/dermatology/programs/practical-dermatology/ www.dermaspherepodcast.com/ Luke and Michelle have no conflicts of interest.

Hány nanométeren pasztőrözzük a laborban fejt tejet? Mennyit ér a nemzeti mesterséges intelligencia? Jön a lajhárbot, megy a Farmville. Jegyzetek Neuralink B-hét: Röfitbit (https://kaszt.hu/20perc/126) Two Minute Papers: Neuralink (https://www.youtube.com/watch?v=JKe53bcyBQY) Follow-up: melyik űrszonda esik a fejünkre mikor? (https://sattrackcam.blogspot.com/2020/05/the-kosmos-482-descent-craft-imaging.html) Follow-up: Okosfarm (https://www.youtube.com/watch?v=6aIbqlgk9S0) High-techenészet: laborban készített tej (https://www.agrarszektor.hu/elemiszer/itt-a-zold-tej-tenyleg-ez-fogja-megmenteni-a-bolygot-a-katasztrofatol.24892.html) 222 nanométeres UV-lámpa (https://www.japantimes.co.jp/news/2020/09/22/national/japan-first-uv-lamp-kills-coronavirus), excimer lámpák (https://en.wikipedia.org/wiki/Excimer_lamp) Robotlajhár (https://boingboing.net/2020/09/22/slothbot-slowly-monitors-the-environment-adorably.html), ugyanez magyarul (https://nlc.hu/eletmod/20200923/robot-lajhar-gennaro-notomista-kornyezetvedelem/) Nemzeti AI (https://www.hwsw.hu/hirek/62340/sztak-kutatolabor-mi-autonom-jarmu-rendszer-itm.html) Menekült a rendőrök elől az önvezető autó (https://www.citynews1130.com/2020/09/17/tesla-self-driving-car-caught-speeding-on-alberta-highway-with-driver-asleep-inside/) Okosserpenyő (https://boingboing.net/2020/09/26/the-hestan-cue-takes-all-the-guesswork-and-culinary-disasters-out-of-cooking.html) Pályázat: termeljünk áramot a Holdon (https://hvg.hu/tudomany/20200929_nasa_herox_hold_kuldetes_elektromos_aram_watts_on_the_moon) Előkerült a legrégebbi számítógép kézikönyve (https://boingboing.net/2020/09/26/missing-manual-for-worlds-oldest-surviving-computer-found.html) Megszűnik a FarmVille (https://www.eurogamer.net/articles/2020-09-28-farmville-will-shut-down-on-december-31st-2020) Mit kezdenénk a mai tudásunkkal, ha visszamehetnénk egy évvel a múltba? (https://twitter.com/waitbutwhy/status/1309885933370716161) Itt a hírlevelünk! (http://eepurl.com/g7Bfd1)

The body depends on the proper functioning and regenerating of its cells and whenever they lose their ability to multiply correctly, that's when a chronic disease starts to occur.So what really makes a cell malfunction?My guest today, forced by life-threatening circumstances, found the answer to this question, and he is the man who is going to change the face of medicine, as we know it today. I know this is a bold statement, but I've experienced first-hand his theory and practical ways to heal my body, and I'm sure that after listening to this episode, you too will look at your body with a different lens – one that gives hope to those who were told by their physicians, “There's nothing we can do.”Dr. Jerry Tennant's life, dedicated to healing and innovation, has changed the paradigm of western medicine. He is one of the most awarded ophthalmologists of his generation and he was one of the first surgeons in the U.S. to place intraocular lenses in eyes after cataract surgery, eliminating the need for thick, incapacitating glasses – and taught his technique around the world.Dr. Tennant is known for many great accomplishments, but there is one that though was revolutionary, has had a definite impact on his health and the groundbreaking discoveries he made. As a pioneer in LASIK surgery, Dr. Tennant was responsible for most of the research done on the Excimer laser for VISX. Due to performing countless laser operations in times when it was believed that the ordinary surgical masks were sufficient to protect doctors from contamination, in time, he developed encephalitis and a bleeding disorder that ended his career as a surgeon.He was told by his physicians that there was nothing they could do for him, but he wasn't going to give up and was determined to find a cure for the chronic disease that was affecting his wellbeing. He started focusing on the cell, and that's when it all began!Listen to Episode 05 of Cure For The Common Life, and be prepared to be mind-blown by the way Dr. Tennant not only found a way to cure his particular affection, but his discoveries are universal and used now to either prevent or heal chronic diseases of all types. Spoiler alert: we're talking electricity and physics here, but don't worry! You don't have to be either an electrician nor a doctor, to understand this priceless lesson on how voltage is the main driver that allows our body to function.I promise you that Dr. Tennant will rock your world!Some questions I ask:Can you please share with us who you are and what is it that you do? (03:33)What can people with tattoos do to have their body's wiring system completely functional again? (26:51)Can you share with us a little bit about your clinic? What can people do to get more information about you? (29:30)What are some simple things that anybody can do now, during this pandemic, to keep their voltage and their oxygen in the normal ranges? (30:13)In this episode, you will learn:How the pH influences the capability of any cell to run properly. (06:13)How a chronic disease manifests in our bodies, at a cellular level. (09:34)The three essential conditions that will help a body start healing if all of them are met at the same time. (11:21)The meaning of piezoelectricity and the importance of movement and exercise for recharging our bodies. (12:16)How the body's wiring system works. (15:07)The importance of the thyroid hormone T3 for our bodies. (18:04)How scars or even tattoos affect our body's wiring system and prevents it from recharging. (19:04)The way our emotions impact our bodies – explained through the lens of electricity. (20:35)How to easily detox a body, using the principle of ‘destructive interference'. (24:44)The importance of going outside for walks, every day & and how the immune system uses ozone to kill the bugs in our bodies. (32:39)Connect with Dr. Tennant:WebsiteContact number: 972-580-1156 See acast.com/privacy for privacy and opt-out information.

The body depends on the proper functioning and regenerating of its cells and whenever they lose their ability to multiply correctly, that’s when a chronic disease starts to occur.So what really makes a cell malfunction?My guest today, forced by life-threatening circumstances, found the answer to this question, and he is the man who is going to change the face of medicine, as we know it today. I know this is a bold statement, but I’ve experienced first-hand his theory and practical ways to heal my body, and I’m sure that after listening to this episode, you too will look at your body with a different lens – one that gives hope to those who were told by their physicians, “There’s nothing we can do.”Dr. Jerry Tennant’s life, dedicated to healing and innovation, has changed the paradigm of western medicine. He is one of the most awarded ophthalmologists of his generation and he was one of the first surgeons in the U.S. to place intraocular lenses in eyes after cataract surgery, eliminating the need for thick, incapacitating glasses – and taught his technique around the world.Dr. Tennant is known for many great accomplishments, but there is one that though was revolutionary, has had a definite impact on his health and the groundbreaking discoveries he made. As a pioneer in LASIK surgery, Dr. Tennant was responsible for most of the research done on the Excimer laser for VISX. Due to performing countless laser operations in times when it was believed that the ordinary surgical masks were sufficient to protect doctors from contamination, in time, he developed encephalitis and a bleeding disorder that ended his career as a surgeon.He was told by his physicians that there was nothing they could do for him, but he wasn’t going to give up and was determined to find a cure for the chronic disease that was affecting his wellbeing. He started focusing on the cell, and that’s when it all began!Listen to Episode 05 of Cure For The Common Life, and be prepared to be mind-blown by the way Dr. Tennant not only found a way to cure his particular affection, but his discoveries are universal and used now to either prevent or heal chronic diseases of all types. Spoiler alert: we’re talking electricity and physics here, but don’t worry! You don’t have to be either an electrician nor a doctor, to understand this priceless lesson on how voltage is the main driver that allows our body to function.I promise you that Dr. Tennant will rock your world!Some questions I ask:Can you please share with us who you are and what is it that you do? (03:33)What can people with tattoos do to have their body’s wiring system completely functional again? (26:51)Can you share with us a little bit about your clinic? What can people do to get more information about you? (29:30)What are some simple things that anybody can do now, during this pandemic, to keep their voltage and their oxygen in the normal ranges? (30:13)In this episode, you will learn:How the pH influences the capability of any cell to run properly. (06:13)How a chronic disease manifests in our bodies, at a cellular level. (09:34)The three essential conditions that will help a body start healing if all of them are met at the same time. (11:21)The meaning of piezoelectricity and the importance of movement and exercise for recharging our bodies. (12:16)How the body’s wiring system works. (15:07)The importance of the thyroid hormone T3 for our bodies. (18:04)How scars or even tattoos affect our body’s wiring system and prevents it from recharging. (19:04)The way our emotions impact our bodies – explained through the lens of electricity. (20:35)How to easily detox a body, using the principle of ‘destructive interference’. (24:44)The importance of going outside for walks, every day & and how the immune system uses ozone to kill the bugs in our bodies. (32:39)Connect with Dr. Tennant:WebsiteContact number: 972-580-1156 See acast.com/privacy for privacy and opt-out information.

Jeffrey Kraws, president of Ra Medical discusses DABRA (Destruction of Arteriosclerotic Blockages by laser Radiation Ablation) with the minimally invasive Pharos Excimer Laser for the treatment of vascular and skin diseases.

Download Episode! Nathalie discusses different UVB treatments available, medications used, insurance coverage of UVB treatments for vitiligo, and the results that she experienced in her vitiligo.

Guest: Dan Reinstein, MD, RCPSC, FRCSC, FRCOphth Medical Director, London Vision Clinic London, UK

Durch moderne Laserspektroskopie ist es mittlerweile möglich, chemische Reaktionen mit einer Zeitauflösung von wenigen Femtosekunden zu untersuchen. Auf der anderen Seite kann die Molekülstruktur mithilfe von Röntgenstrukturanalyse sehr exakt bestimmt werden. Die vorliegende Doktorarbeit beschäftigt sich damit, diese beiden Gebiete zusammenzubringen. Der erste Teil der Dissertation beschreibt den Aufbau einer Laserplasmaquelle am Lehrstuhl für BioMolekulare Optik. Ein hochenergetischer Laserimpuls wird in einer Vakuumkammer auf ein Kupferband fokussiert. Dabei entsteht charakteristische Kupfer-K-alpha-Strahlung, die auf die kristalline Probe abgebildet wird. Ein zweiter Laserimpuls induziert in der Probe eine chemische Reaktion, die die Kristallstruktur ändert. Mit diesem Aufbau sind Röntgenbeugungsmessungen mit einer Zeitauflösung von wenigen hundert Femtosekunden möglich. An einem möglichen Probenkristall, DIABN, wurden zudem Transmissionsmessungen mit einer Röntgen-Streak-Kamera durchgeführt. Dieses Molekül zeigt einen Ladungstransferzustand auch in der kristallinen Phase, welcher mit einer Strukturänderung einhergeht. Der Ladungstransfer beeinflusst aber auch die Ausrichtung der umgebenden Moleküle, was die Extinktion des Kristalls stark verändert. Dieser Effekt kann mit zeitaufgelösten Transmissionsmessungen untersucht werden, bevor Röntgenbeugungsexperimente durchgeführt werden. Der Hauptteil der Dissertation handelt von der Excimerbildung in 9,10-Dichloroanthrazen (DCA). Mit zeitaufgelöster Emissions- und Absorptionsspektroskopie wurde zunächst das Verhalten in Lösung beobachtet. Hier konnte erstmals eine detaillierte Studie zur Konzentrationsabhängigkeit der Excimerbildung von DCA erstellt werden. Mit den dabei gewonnen Erkenntnissen konnte eine vergleichende Untersuchung der beiden Kristallformen, alpha und beta, durchgeführt werden. Entgegen andersartigen Darstellungen in der Literatur konnte gezeigt werden, dass in der alpha-Form keine Excimerbildung stattfindet, während für die beta-Form die Bildungsrate bei Raumtemperatur bestimmt werden konnte. Die experimentellen Befunde lassen sich wie folgt erklären: Während in Lösung die Bildungsrate mit der Konzentration steigt, da es ein diffusionskontrollierter Prozess ist, sind im Kristall die beteiligten Moleküle relativ starr im Kristallgitter fixiert. In der beta-Form verhindert die relative Anordnung der Moleküle eine Excimerbildung, wohingegen in der alpha-Form die Moleküle fast perfekt parallel ausgerichtet sind und innerhalb kürzester Zeit ein Excimer bilden. Dieses System ist eine ideale Probe für die neu aufgebaute Laserplasmaquelle.

In this episode, Dr Berlin and I discuss the elusive quest to have the Excimer Laser Trabeculostomy (ELT) that he pioneered gain traction after 30 years of development. (This is the AAC enhanced version with chapter markers and images optimized for iOS devices and computers; see mp3 version for most other devices.)

In this episode, Dr Berlin and I discuss the elusive quest to have the Excimer Laser Trabeculostomy (ELT) that he pioneered gain traction after 30 years of development. (See the enhanced AAC version of this same episode for a version with chapter markers and images; not compatible on all devices but ideal version for iOS or computers.)

Commentary from William Trattler, MD. This year

Host: Larry Kaskel, MD Guest: Mani Bhaumik, PhD The excimer laser was the key component to the invention of lasik surgery, responsible to returning nearly perfect vision to millions of people. How was the excimer laser developed and how did it turn into a miracle capable of correcting vision? Join Dr. Larry Kaskel talking with the co-inventor of the excimer laser, Dr. Mani Bhaumik.

Host: Larry Kaskel, MD Guest: Mani Bhaumik, PhD The excimer laser was the key component to the invention of lasik surgery, responsible to returning nearly perfect vision to millions of people. How was the excimer laser developed and how did it turn into a miracle capable of correcting vision? Join Dr. Larry Kaskel talking with the co-inventor of the excimer laser, Dr. Mani Bhaumik.

Paper Discussed: Richard J. Mackool, MD, Wilson Ko, MD, Richard Mackool, MDIntraocular lens power calculation after laser in situ keratomileusis: Aphakic Refraction technique Journal of Cataract and Refractive Surgery 2006 March; 32: 430-434Guest: Wilson Ko, M.D.Attending SurgeonNew York Eye and Ear InfirmaryNew York, New York

Guest: Keith A. Walter, M.D.Assistant Professor of Ophthalmology Wake Forest University School of Medicine Winston-Salem, NC

Samuel Masket, M.D.President of The American Society of Cataract and Refractive SurgeryClinical Professor of OphthalmologyJules Stein Eye InstituteGeffen School of MedicineU.C.L.A. Los Angeles, CA