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You HAVE to see this — Anthropic just hit a $965 BILLION valuation, and now the company is calling for a global AI slowdown … but here's the real question: If America pauses, will China actually stop? Pat Gray tears apart this latest move from Big Tech. After warning that its own models are too dangerous and quietly releasing a “safe” version, Anthropic now wants the world to hit the brakes on frontier AI development. Sounds noble — until you realize China is never going to play along. We also cover: Rest in peace, “Uncle Jimmy” Dodds. Why did Bill Gates testify in Congress? Does America have an Indian immigration problem? Knicks' EPIC comeback in Game 4 Democrats are UPSET at the Bidens. This isn't about safety. It's about crippling American innovation while our biggest adversary races full speed ahead to dominate AI for military, cyber, and economic supremacy. National security experts know the country that leads in AI will lead the world — and right now, elites in Silicon Valley are pushing policies that could hand that advantage straight to the Chinese Communist Party. Drop your hottest take — let's talk about what real America First AI policy should look like. If you're tired of Big Tech elites risking our national security while pretending to be the adults in the room, smash that LIKE button, SUBSCRIBE, and turn on notifications for more hard-hitting conservative analysis. 00:00 Pat Gray UNLEASHED! 00:52 Iran, and the Rising Gas/Oil Prices 01:45 Trump on When Gas/Oil Prices will Go Down 03:34 Current Price of Gas/Oil 05:39 Trey Yingst on Bombing Campaign against Iran 09:41 Trump Signs Homeland Security Bill 10:27 Trump on Bill Pulte for DNI 13:30 Trump on Inflation 17:21 Cowboys & Indians Song Controversy 22:14 News Headline Regarding the Karmelo Anthony Verdict 25:54 Jasmine Crockett on Karmelo Anthony Verdict 27:40 Jasmine Crockett on Race / Austin Metcalf's Family 30:40 Fat Five 40:54 Special 'Disclosure Day' Episode TOMORROW! 43:19 Anthropic Calls for Pausing AI Development Worldwide 50:00 The Advancements & Dangers of AI 57:21 John Thune Sucks! 59:20 Jim Jordan VS. ActBlue 1:03:37 Knicks Fans Burning Down New York 1:07:02 Eric Schmitt Baseball Catch 1:09:04 News Report on Bill Gates/Jeffrey Epstein Connection 1:12:13 RIP James 'Uncle Jimmy' Dodds 1:14:42 Dems Not Happy with Biden Family 1:17:52 Candace Owens Wants Everyone to Go to Russia??? 1:30:39 Texas Judge Denise Hernández Learn more about your ad choices. Visit megaphone.fm/adchoices
Sign up for weekly webinars:Weekly Webinars - Independent Medical Alliance https://imahealth.org/weekly-webinars/What should patients, physicians, and families understand about ivermectin beyond the headlines?In this episode of the IMA Weekly Show, Dr. Ryan Cole is joined by Dr. Joseph Varon for “Ivermectin: The Good, The Bad, and the Emerging Science.”Dr. Varon begins with a presentation on ivermectin's discovery, history, global use as an antiparasitic medication, and the broader mechanisms now being studied in medical research. Dr. Cole and Dr. Varon then continue the conversation with a practical discussion about clinical judgment, safety, controversy, and where the emerging science may be headed.This episode covers:• Ivermectin's history and established medical uses• Antiparasitic, antiviral, anti-inflammatory, and immune-related mechanisms• COVID-era controversy and what physicians saw clinically• Human formulations, dosing, safety, and drug interactions• Emerging research on cancer, post-vaccination syndrome, and parasite-related concernsThe Independent Medical Alliance (formerly FLCCC) is a healthcare nonprofit on a mission to restore trust, integrity, and the doctor-patient relationship. Get involved by clicking below:• Donate: Support IMA: Donate for Advancements in Patient Care https://imahealth.org/donate/• Follow: Connect with Us - https://imahealth.org/contact/• Weekly Webinars: - https://imahealth.org/category/weekly-webinars/• Treatment Protocols: - https://imahealth.org/treatment-protocols/• Medical Disclaimer: https://imahealth.org/about/terms-and-conditions/
In this episode of Open Web Conversations, Zach Stepek and Carl Alexander discuss with Alex Standiford the impact of AI on developers, highlighting productivity, burnout, workflow changes, and the necessity of setting boundaries in this rapidly evolving landscape.
Stay informed on current events, visit www.NaturalNews.com - AI Bubble and Revenue Models (0:10) - Corporate Misuse of AI (2:25) - Token Maxing and AI Productivity (7:02) - Investment Advice and Open Source AI (10:28) - Scientific Community and Depopulation Agenda (14:45) - AI and Humanity's Future (23:50) - Government and Corporate Control (37:51) - Ethical Use of AI (1:05:51) - AI and Human Intelligence (1:06:08) - Resilience and Red-Pilling (1:11:45) - Discussion on EVs and Ethanol (1:14:34) - Advancements in Battery Technology (1:16:16) - Historical Context of EVs (1:18:56) - Political Discussion on Trump and Israel (1:20:41) - Economic and Political Challenges (2:00:28) - Bitcoin and Financial Freedom (2:00:53) - Future Outlook and Personal Reflections (2:12:42) - Discussion on Banking and Crime (2:14:40) - Generational Perspectives and Closing Remarks (2:16:40) Watch more independent videos at http://www.brighteon.com/channel/hrreport ▶️ Support our mission by shopping at the Health Ranger Store - https://www.healthrangerstore.com ▶️ Check out exclusive deals and special offers at https://rangerdeals.com ▶️ Sign up for our newsletter to stay informed: https://www.naturalnews.com/Readerregistration.html Watch more exclusive videos here:
Diabetes Dialogue: Therapeutics, Technology, & Real-World Perspectives
Welcome back to Diabetes Dialogue: Technology, Therapeutics, & Real-World Perspectives!In this special episode recorded live at the American Diabetes Association (ADA) Scientific Sessions 2026 in New Orleans, Louisiana, cohosts Diana Isaacs, PharmD, and Natalie Bellini, DNP, welcome Trang Ly, PhD, MBBS, senior vice president and Chief Medical Officer at Insulet, to discuss the continued evolution of automated insulin delivery (AID) technology and emerging developments across the Omnipod platform. To begin the episode, Ly first reviews updates to Omnipod 5, focusing on enhancements aimed at increasing time in automated mode and improving glucose management. She explains that user feedback identified opportunities to support lower glucose targets and reduce interruptions related to system alerts. Data from real-world evidence and computer simulations suggest that lowering the glucose target from 110 to 100 mg/dL may lead to meaningful improvements in time in range and time in tight range without increasing hypoglycemia risk.The group discusses early clinical experience with these enhancements, including findings from users who transitioned to the updated system. Ly highlights that even a highly engaged population already using lower targets experienced additional improvements, including a 2% increase in time in range and a 5% increase in time in tight range over a short period of use. The conversation emphasizes the importance of making these improvements broadly available rather than waiting for routine follow-up visits, particularly given the potential benefits without additional safety concerns.The discussion then turns to Omnipod 6, with Ly sharing newly presented clinical trial data evaluating the next-generation system. She describes the study design, which enrolled users already achieving strong glycemic control on Omnipod 5 and assessed whether further intensification through algorithm improvements could safely provide additional benefits. The results demonstrated a 4% improvement in time in range and up to a 7% increase in time in tight range, with particularly notable improvements among individuals with type 1 diabetes aged 14 years and older.Ly explains that Omnipod 6 builds on previous technology through changes to the core algorithm, allowing the system to deliver more insulin when users do not bolus consistently. The panel explores how this approach may reduce the burden of diabetes management by allowing the algorithm to take on more responsibility while maintaining glycemic control. They discuss the potential psychological benefits of reducing the daily demands placed on people with diabetes, especially as sensor accuracy and automation continue to improve.The conversation also highlights future opportunities for AID in type 2 diabetes. Ly shares early feasibility data from a fully closed-loop system designed specifically for individuals with type 2 diabetes, emphasizing its simplified approach without requiring traditional pump programming or meal bolusing. In this study, participants experienced improvements in time in range, demonstrating the potential for automated insulin delivery to reach broader populations.Isaacs and Bellini discuss the need to reconsider barriers to insulin pump adoption in type 2 diabetes and recognize AID as an accessible option for patients who may benefit. Ly emphasizes that technology should support people across different levels of engagement, offering both highly customizable systems for those seeking intensive management and simpler automated approaches for those looking to reduce daily treatment demands.The episode concludes with a discussion of the future of diabetes technology, including improved connectivity, expanded device flexibility, and continued integration with complementary therapies such as GLP-1 receptor agonists. Ly underscores that innovation should not only improve clinical outcomes but also reduce the burden of care, allowing people with diabetes to spend less time managing their condition and more time living their lives.Editors' Note: Isaacs reports disclosures with Dexcom, Abbott, Lilly, Novo Nordisk, Medtronic, Insulet, and others. Bellini reports disclosures with Abbott Diabetes Care, MannKind, Povention Bio, and others. Ly reports a disclosure with Insulet.References1: Insulet. Insulet Reveals New Data Supporting Breakthrough Omnipod 6 and Fully Closed-Loop AID Systems Designed to Improve Outcomes, Reduce Effort, and Unlock Barriers to Care. June 6, 2026. Accessed June 7, 2026. https://investors.insulet.com/news/news-details/2026/Insulet-Reveals-New-Data-Supporting-Breakthrough-Omnipod-6-and-Fully-Closed-Loop-AID-Systems-Designed-to-Improve-Outcomes-Reduce-Effort-and-Unlock-Barriers-to-Care/default.aspx
Our 247th episode with a summary and discussion of last week's big AI news!Recorded on 06/03/2026Hosted by Andrey Kurenkov and Jeremie HarrisFeel free to email us your questions and feedback at andreyvkurenkov@gmail.com and/or hello@gladstone.aiRead out our text newsletter and comment on the podcast at https://lastweekin.ai/In this episode:Anthropic released Claude Opus 4.8 with improved benchmark scores, discussed eval-awareness findings and welfare/corrigibility themes from its system card, and introduced Dynamic Workflows for long-running multi-agent tasks.Microsoft unveiled the always-on Microsoft Scout assistant built on OpenClaw plus new in-house MAI models (including MAI Thinking 1) and “frontier tuning,” emphasizing enterprise security architecture and model-from-scratch capability.Major business moves included Anthropic's $65B Series H at a $965B valuation alongside an IPO filing, a JPMorgan analysis arguing OpenAI needs major revenue growth to justify infrastructure spend, and Cognition raising $1B at a $25B valuation.Policy and security highlights covered Trump's voluntary pre-release government testing framework for powerful AI, Meta AI support being exploited to hijack Instagram accounts, tightened US Nvidia export controls and China's travel approvals for AI experts, plus expanded Glasswing/Mythos-style cyber and biodefense initiatives.Timestamps:(00:00:10) Intro / Banter(00:04:10) Sponsors(00:07:10) News PreviewTools & Apps(00:07:54) Anthropic releases Opus 4.8 with new 'dynamic workflow' tool | TechCrunch(00:22:37) Microsoft Scout is a new AI personal assistant built on OpenClaw | The Verge(00:26:55) Microsoft launches new MAI family of AI models at Microsoft Build | Mashable(00:37:43) Robinhood now lets your AI agents trade stocks | TechCrunch(00:40:49) OpenAI launches new Codex tools for white-collar work | TechCrunch(00:43:40) ElevenLabs' new music-generation model can switch genres mid-track | TechCrunchApplications & Business(00:44:35) Anthropic Hits $965 Billion Valuation, Surpassing OpenAI - WSJ(00:45:32) Anthropic Files to Go Public, Setting Stage for Huge I.P.O. - The New York Times(00:51:15) China's ByteDance Developing New AI Chips Like Those from Nvidia Partner Groq(00:55:00) Anthropic expands Mythos to 150 additional organizations(00:55:35) OpenAI needs a 26x revenue increase to justify its buildout(00:58:46) AI coding startup Cognition raises $1B at $25B pre-money valuation | TechCrunchProjects & Open Source(01:00:50) MiniMax-M3 debuts, eclipsing GPT-5.5 and Gemini 3.1 Pro on key benchmark performance for just 5-10% of the cost | VentureBeatPolicy & Safety(01:06:08) Trump Signs Executive Order Seeking Oversight of A.I. Models - The New York Times(01:11:45) Hackers Simply Asked Meta AI to Give Them Access to High-Profile Instagram Accounts. It Worked(01:13:058) Chinese AI experts in private firms now required to secure approval before international travel — Beijing enforces policy to secure top-tier talent, expands measures beyond government(01:17:53) U.S. Tightens Controls on Nvidia AI Chip Exports | Let's Data Science(01:21:47) OpenAI launches Rosalind Biodefense, offers federal agencies early access to its life-sciences model(01:24:00) Using LLMs to secure source code(01:26:19) Project Glasswing: An initial update(01:29:30) White House Approves $9 Billion for Spy Agencies to Catch Up on A.I.(01:32:11) US Law Enforcement Warns of ‘Anti-Tech Extremism' as AI Hatred GrowsSynthetic Media & Art(01:35:38) YouTube will now automatically label AI videos | TechCrunchResearch & Advancements(01:36:22) Why Larger Models Learn More: Effects of Capacity, Interference, and Rare-Task Retention(01:41:26) From Simulation to Enaction: Post-trained language models recognize and react to their own generationsSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
The war in Ukraine has fundamentally altered the strategic environment for Russia on its western border. The conflict has expanded the line of contact with NATO and the alliance's partners in Ukraine, and it now stretches all the way from the Arctic Ocean to the Black Sea. The nature of the relationship has also changed profoundly, with NATO viewing Russia as a generational threat, and Ukraine emerging as an aggrieved and highly militarily capable nation keen to settle scores with the Kremlin. Advancements in technology have also revolutionized the war and made the strategic landscape far more worrisome for Russia. How does Moscow perceive these changes? And how might future generations of the state security establishment address the challenges? For more in-depth analysis, read Eugene Rumer's paper, Belligerent and Beleaguered: Russia After the War with Ukraine.
Sign up for weekly webinars:Weekly Webinars - https://imahealth.org/weekly-webinars/Fertility is more than a reproductive issue. It can be a window into whole-body health.More couples are struggling to conceive, birth rates are falling, and many families are left wondering why. The answers are rarely simple, but they are worth looking for.In this episode, Dr. Kat Lindley is joined by Dr. Kimberly Biss for a practical conversation on infertility, declining birth rates, and the many factors that can influence reproductive health in both women and men.Dr. Biss discusses ovarian reserve, ovulatory dysfunction, sperm count and motility, hormone balance, PCOS, endometriosis, thyroid and adrenal health, metabolic factors, lifestyle, nutrition, sleep, stress, environmental exposures, and emerging research related to fertility, pregnancy, and infant outcomes.In this episode, you'll learn:• Why declining birth rates matter• How infertility is commonly defined and evaluated• Female and male factors that can affect fertility• Why hormones, metabolism, thyroid function, and inflammation matter• How lifestyle and environmental exposures may play a role• What emerging research is examining about fertility and pregnancy outcomes• Practical ways to support reproductive healthFor anyone walking through fertility questions, this conversation offers a grounded place to begin with better questions, a wider lens, and renewed hope for healing.The Independent Medical Alliance (formerly FLCCC) is a healthcare nonprofit on a mission to restore trust, integrity, and the doctor-patient relationship. Get involved by clicking below:• Donate: Support IMA: Donate for Advancements in Patient Care https://imahealth.org/donate/• Follow: Connect with Us - https://imahealth.org/contact/• Webinar: Weekly Webinars - https://imahealth.org/category/weekly-webinars/• Treatment: Treatment Protocols - https://imahealth.org/treatment-protocols/• Medical Disclaimer: https://imahealth.org/about/terms-and-conditions/
Microsoft has announced a series of updates at its Build 2026 conference, introducing a new platform for AI agents, seven new in-house AI models and a range of developer platform capabilities designed to support a new era of "ubiquitous intelligence". The company said the announcements are focused on enabling developers to build, deploy and manage intelligent systems with greater flexibility, control and security, while meeting enterprise requirements for governance and trust. Central to the updates is the new Microsoft Agent Platform, which allows developers to build agents using organisational context through Microsoft IQ, deploy them via Microsoft Foundry and access them across Microsoft Teams and Microsoft 365. Microsoft said the platform is designed to reduce trade-offs between context and governance, security and speed, and between models and tools. Microsoft also announced that Microsoft IQ is now generally available across GitHub Copilot, Microsoft Foundry and Copilot Studio, providing a unified context layer across enterprise and external data. New capabilities include Work IQ, which captures how work happens across Microsoft 365, organisational systems and external sources, and Web IQ, an AI-first web search stack announced at Build that delivers real-time grounding for agents. Alongside the platform, Microsoft unveiled a new family of seven in-house AI models, including MAI-Thinking-1, its first reasoning model optimised for complex, multi-step tasks. Additional models span image generation, transcription, voice and coding, reinforcing what Microsoft described as a multi-model ecosystem. The company also introduced new tools across the stack, including Microsoft Execution Containers, now in preview, which provide secure, operating-system-enforced sandboxes for agents. The Foundry Agent Service, also in preview, for cloud-scale managed agent deployment; and the GitHub Copilot app, in preview, which brings agent-driven development workflows to a native desktop experience. Beyond software development, Microsoft highlighted applications in scientific research through its Microsoft Discovery platform, which is now generally available as an enterprise AI solution for the full scientific workflow. The company also outlined progress in quantum computing with its next-generation Majorana 2 chip, citing significant improvements in qubit reliability and a path towards a scalable quantum system later this decade. Microsoft said these advancements aim to position developers at the centre of innovation in the AI era, giving them greater agency to build intelligent systems with enterprise-grade controls and trust. See more stories here.
Preview for Later Today: Mary Kissel addresses the Trump administration's stance on NATO, stressing that support remains strong for Ukraine. She urges European capitals to prioritize defense while commending Ukraine's impressive advancements in domestic military industrial innovation.1903 BRUSSELS
Childrens Day
This is the Everyday AI episode we probably shoulda done a while ago....
This episode is sponsored by NovaQuis Health.During this live recording from Fetch Nashville of The Vet Blast Podcast presented by dvm360, our host Adam Christman, DVM, MBA, teamed up with colleagues to break down the latest in wound care. Joined by Justin Ganjei, DVM, DACVS-SA, and Kelly Sovey DVM, CVA, the trio highlighted how critical vascular preservation and tracking the precise stages of healing are to a patient's recovery.
In a recent interview with CancerNetwork®, Nicholas Hornstein, MD, PhD, an assistant professor at the Donald and Barbara Zucker School of Medicine of Hofstra University and Northwell Health, discussed emerging data and clinical shifts in the care of patients with gastrointestinal (GI) cancers ahead of the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting.Advancements in Colorectal CancerHornstein highlighted the increasing integration of targeted therapies into the first-line setting for patients with colorectal cancer (CRC). For those with BRAF V600E-mutated metastatic disease, data from the phase 3 BREAKWATER trial (NCT04607421) support moving targeted therapy into the first line.1 He noted that initiating these therapies early is critical, as a significant percentage of patients may experience rapid clinical decline and lose the opportunity for second-line treatment if targeted options are delayed.In the HER2-positive space, clinicians currently utilize tucatinib (Tukysa)-based regimens or fam-trastuzumab deruxtecan-nxki (Enhertu). Hornstein also anticipated the arrival of bispecific antibodies, such as zanidatamab-hrii (Ziihera), which are expected to gain approval in upper GI cancers before moving into the CRC landscape.The Role of ctDNA and Pancreatic CancerRegarding localized disease, Hornstein discussed the potential for circulating tumor DNA (ctDNA) to guide adjuvant therapy for patients with stage II colon cancer. Data from trials like CIRCULATE (NCT05174169) are expected to further clarify how ctDNA can assist in the escalation or de-escalation of treatment.2 In pancreatic cancer, the phase 3 RASolute 302 trial (NCT06625320) investigating daraxonrasib is poised to change the standard of care for patients with second-line pancreatic cancer immediately upon an anticipated regulatory approval.3Barriers to Precision MedicineA primary unmet need that Hornstein identified was the low rate of biomarker testing; currently, only about half of patients with metastatic disease receive necessary sequencing or microsatellite instability testing. Hornstein emphasized that multidisciplinary cooperation and improved systems are essential to ensure all patients with targetable mutations receive appropriate care. Finally, he highlighted the development of large language model tools to assist clinicians with data ingestion and clinical trial matching.References1. Kopetz S, Wasan HS, Yoshino T, et al. BREAKWATER: primary analysis of first-line (1L) encorafenib + cetuximab (EC) + FOLFIRI in BRAF V600E-mutant metastatic colorectal cancer (mCRC). J Clin Oncol. 2026;44(suppl 2):13. doi:10.1200/JCO.2026.44.2_suppl.132. Dasari A, Yu G, Kopetz S, et al. NRG-GI008: colon adjuvant chemotherapy based on evaluation of residual disease (CIRCULATE-NORTH AMERICA). J Clin Oncol. 2026;44(suppl 16):TPS3686. doi:10.1200/JCO.2026.44.16_suppl.TPS36863. Wolpin B, Wainberg ZA, Hendifar A, et al. Daraxonrasib, a RAS(ON) multi-selective inhibitor vs chemotherapy in previously treated metastatic pancreatic adenocarcinoma (mPDAC): Primary and final analysis from the phase 3 RASolute 302 study. J Clin Oncol. 2026;44(suppl 17):LBA5. doi:10.1200/JCO.2026.44.17_suppl.LBA5
Stay informed on current events, visit www.NaturalNews.com - Strait of Hormuz and Peak Oil (0:10) - Advancements in Solar Energy and Cold Fusion (2:17) - Impact of Oil Demand and Middle East Dependence (3:58) - Logistical Challenges and Diesel Shortages (6:25) - Preparation for Energy Shortages and Maintenance (9:51) - Nocebo Effect and Medical Fear Campaigns (20:35) - Critique of Modern Medicine and Vaccines (44:05) - Microplastics and Clothing Choices (1:00:35) - Interview with David Dubeyne on Food Shortages (1:12:47) - Impact of Fuel Shortages and Economic Implications (1:15:38) - Psychological Operations and Energy Lockdowns (1:19:47) - Plastic Shortages and Food Packaging Issues (1:21:41) - El Nino and Its Impact on Crop Production (1:26:11) - Global Water Shortages and Data Center Competition (1:31:34) - African and Middle Eastern Food Production (1:39:10) - Changes in Global Agricultural Hubs (1:41:33) - Preparation for Food Shortages and Economic Changes (1:51:16) - Historical Analogies and Economic Predictions (1:58:38) - Final Thoughts and Call to Action (1:59:53) Watch more independent videos at http://www.brighteon.com/channel/hrreport ▶️ Support our mission by shopping at the Health Ranger Store - https://www.healthrangerstore.com ▶️ Check out exclusive deals and special offers at https://rangerdeals.com ▶️ Sign up for our newsletter to stay informed: https://www.naturalnews.com/Readerregistration.html Watch more exclusive videos here:
After reading a much-too-long epic (that really could've been boiled down to a single episode), we decided we needed a palette cleanser. For some reason, we also decided that palette cleanser would be Hans Christian Andersen. This week, we read The Rose Elf. Suggested talking points: Advancements in Bellibolt Technology, Excommunicated from the Pinocchio Community, Folktale Chop Shop, Magic Ennui Ball, Nega-Bilbo, Kafka Kourt Check out Gordie's TTRPG, Mythomorphosis If you'd like to support Carman's artistic endeavors, visit: https://www.patreon.com/carmandaartsthings If you like our show, find us online to help spread the word! Follow us on Twitter, Facebook, and Youtube. Support us on Patreon to help the show grow at www.patreon.com/wtfolklore. You can find merchandise and information about the show at www.wtfolklorepodcast.com.
Penny and Midge wade into the world of the mermaid. What's the lore behind this beloved mythical creatures, and what do they represent in the world of horror? Join the conversation on the Ghouls Night In discord! Follow the ghouls on instagram at @ghoulsnightinpod Cover art by Alex Zimdars
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Let us know what you think! Security Halt's Med Group - https://zcform.com/QA5QsClick the link for a FREE consultation with My Med Team to see how we can help. What if trauma treatment could target the nervous system directly instead of relying solely on years of therapy and medication?In Episode 436 of the Security Halt! Podcast, we sit down with Dr. Eugene Lipov, the pioneering physician behind the Stellate Ganglion Block (SGB) for PTSD treatment. Dr. Lipov shares the origin story of SGB, the neuroscience behind fight-or-flight trauma responses, and how this groundbreaking procedure is helping veterans, first responders, and trauma survivors find rapid relief.This conversation goes beyond PTSD treatment. Dr. Lipov also discusses digital addiction, sleep hygiene, social media's impact on mental health, family-centered healing, and why purpose and community are critical for long-term resilience.Chapters00:00 Introduction to the Stellate Ganglion Block02:52 Eugene Lipov's Journey into Medicine06:01 The Discovery of Stellate Ganglion Block for PTSD08:55 Understanding the Impact of SGB on Trauma11:50 The Procedure: How Stellate Ganglion Block Works14:48 Advancements in SGB Techniques17:52 Real-Life Impact: Patient Stories and Outcomes21:13 The Future of PTSD Treatment and Digital PTSD23:55 Maintaining Passion in Medicine27:34 The Impact of Digital Media on Society30:26 The Rise of Digital Detox and Technoference34:38 The Dangers of Digital Addiction39:13 The Importance of Sleep and Mental Health45:55 Addressing Trauma and Family Dynamics51:58 Finding Purpose and Healing in LifeSponsored by: Transcend Use my referral link to book a consultation for Peptide Therapy http://transcendcompany.com/DenyCaballero Pure Liberty Labs Use Code: SECURITY_HALT_10 Instagram: https://www.instagram.com/purelibertylabs/ Website: https://purelibertylabs.com/ PRECISION WELLNESS GROUP Use code: Security Halt Podcast 25 Website: https://www.precisionwellnessgroup.com/ SPECIAL FORCES FOUNDATION Instagram: https://www.instagram.com/specialforcesfoundation_/ Website: https://specialforcesfoundation.org/ Request Help: https://specialforcesfoundation.org/get-support/ Security Halt Mediahttps://www.securityhaltmedia.com/Instagram: @securityhaltX: @SecurityHaltTik Tok: @security.halt.podLinkedIn: Deny Caballero Support the showProduced by Security Halt Media
Stay informed on current events, visit www.NaturalNews.com - Memorial Day Message and Introduction to Energy Technology (0:02) - Impact of the War in Iran on Energy Technology (3:59) - Commercialization and Future of LENR Technology (8:00) - Challenges and Opportunities in Energy Transition (9:11) - Memorial Day Sale and Store Updates (9:34) - Translation Projects and Future Plans (12:26) - Impact of the War in Iran on Global Energy Supply (14:56) - Advancements in Battery Technology (36:37) - Challenges in Data Center Development (56:16) - Potential for Decentralized Power Production (1:17:59) - X AI's Tactics and Community Pushback (1:18:16) - Health Impact of Gas Turbines (1:20:33) - Community Action and Activist Movements (1:22:41) - Technological Overkill and Data Center Viability (1:29:53) - China's Role in Data Center Scaling (1:33:58) - Digital ID and Surveillance Infrastructure (1:37:57) - The Spiritual and Practical Implications of Data Centers (1:46:01) - The Role of Decentralized Technology (1:53:12) - The Impact of Social Media and Addictions (2:06:28) - The Importance of Natural Dopamine Support (2:11:30) - Impact of Media and Pharma on Public Perception (2:33:51) - Awareness and Establishment Resistance (2:36:03) - Historical and Current Pharma Scandals (2:39:20) - Natural Solutions and Superfoods (2:41:33) - Impact of Toxic Ingredients and Seed Oils (2:45:28) - Glyphosate and Corporate Influence (2:53:25) - Personal Responsibility and Health Awareness (2:57:10) - Addiction Rescue Course and Dopamine Revolution (3:00:05) - Memorial Day Sale and Health Ranger Store (3:03:35) - Final Thoughts and Encouragement (3:08:55) Watch more independent videos at http://www.brighteon.com/channel/hrreport ▶️ Support our mission by shopping at the Health Ranger Store - https://www.healthrangerstore.com ▶️ Check out exclusive deals and special offers at https://rangerdeals.com ▶️ Sign up for our newsletter to stay informed: https://www.naturalnews.com/Readerregistration.html Watch more exclusive videos here:
Our 246th episode with a summary and discussion of last week's big AI news!Recorded on 05/22/2026Hosted by Andrey Kurenkov and Jeremie HarrisFeel free to email us your questions and feedback at andreyvkurenkov@gmail.com and/or hello@gladstone.aiRead out our text newsletter and comment on the podcast at https://lastweekin.ai/In this episode:Google I/O highlights included Gemini 3.5 (with 3.5 Flash emphasized for speed and benchmarks), the always-on agent Gemini Spark running on Google Cloud with MCP tool support, and Gemini Omni multimodal video generation/editing, plus updates like Anti-Gravity 2.0, Gemini for Science, and Genie world-model navigation using Street View and Waymo simulation.Coding-agent competition accelerated with Cursor Composer 2.5 (fine-tuned on Moonshot's Kimi K2.5) and xAI's early Grok Build release, alongside discussion of potential Cursor–xAI ties and xAI's talent churn and compute utilization concerns.Business and legal updates included Elon Musk losing his OpenAI lawsuit on statute-of-limitations grounds, reported OpenAI–Apple partnership tensions, Anthropic agreeing to a $30B funding round at a $900B valuation and projecting its first profitable quarter, and Cerebras' IPO surging about 90%. Research and safety stories covered OpenAI's result on an 80-year-old Erdős geometry problem, findings on “negation neglect” in training, interpretability work showing multiple redundant circuits per capability, agent benchmarks like Terminal World, new deepfake takedown enforcement under the Take It Down Act, demonstrations of autonomous hacking/self-replication, rapidly improving AI cyber capabilities, and steps toward image provenance metadata and watermarks.Timestamps:(00:00:10) Intro / Banter(00:01:15) News PreviewTools & Apps(00:05:05) Google unveils AI model Gemini 3.5 and AI agent Gemini Spark(00:11:43) Google's Gemini Omni turns images, audio, and text into video — and that's just the start | TechCrunch(00:17:27) Google launches Antigravity 2.0 with an updated desktop app and CLI tool at IO 2026 | TechCrunch(00:22:35) Google Debuts AI-Powered Tools To Optimize Scientific Research Workflows(00:27:20) Google's Genie world model can now simulate real streets with Street View | TechCrunch(00:29:51) Cursor's Composer 2.5 matches Opus 4.7 and GPT-5.5 benchmarks at a fraction of the cost(00:37:37) xAI Introduces Its Coding Agent Called Grok BuildApplications & Business(00:41:55) Musk loses OpenAI court battle as he waited too long to sue(00:48:08) Anthropic agrees terms of $30bn funding deal at $900bn valuation(00:53:12) OpenAI co-founder Andrej Karpathy joins Anthropic's pre-training team | TechCrunch(00:56:49) Greg Brockman Officially Takes Control of OpenAI's Products in Latest Shake-Up | WIRED(00:58:15) OpenAI-Apple Partnership Frays, Setting Up Possible Legal Fight - Bloomberg(01:01:13) AI chipmaker Cerebras soars 90% in year's biggest IPO so farResearch & Advancements(01:07:10) AI just solved an 80-year-old ‘Erdős problem,' and mathematicians are amazed | Scientific American(01:11:50) Negation Neglect: When models fail to learn negations in training(01:13:18) All Circuits Lead to Rome: Rethinking Functional Anisotropy in Circuit and Sheaf Discovery for LLMs(01:16:20) Autonomous AI research for nanogpt speedrun(01:21:59) TerminalWorld: Benchmarking Agents on Real-World Terminal TasksPolicy & Safety(01:23:15) America's dangerous, messy deepfakes crackdown is here | The Verge(01:25:17) Language Models Can Autonomously Hack and Self-Replicate(01:28:48) How fast is autonomous AI cyber capability advancing?(01:31:32) Positive Alignment: Artificial Intelligence for Human FlourishingSynthetic Media & Art(01:33:15) OpenAI is making it easier to check if an image was made by their models | TechCrunch(01:33:56) How Chinese short dramas became AI content machines | MIT Technology ReviewSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Stay informed on current events, visit www.NaturalNews.com - Goshen High Tech's Sodium Ion Battery Breakthrough (0:11) - Challenges with Current Battery Technology (4:04) - Advantages of Sodium Ion Batteries (6:37) - Applications and Market Impact (10:42) - Production and Availability (15:21) - Political and Economic Considerations (19:45) - Future Prospects and Personal Reflections (31:56) - China's Advancements in AI and Technology (45:24) - China's Infrastructure and Power Grid (1:04:50) - Conclusion and Final Thoughts (1:08:37) - Cyrus Jansen's Renewable Energy Investment (1:08:49) - Stuart Rhodes' Legal Update (1:11:25) - Challenges Faced by J6 Defendants (1:15:16) - Oath Keepers' Mission and Future Plans (1:19:25) - Deep State and Trump Administration (1:23:10) - Military Deployments and Treatment of Soldiers (1:32:40) - AI and Surveillance Technology (1:38:39) - Strong County Project (1:47:34) - Memorial Day Sale and Health Ranger Store (1:49:56) Watch more independent videos at http://www.brighteon.com/channel/hrreport ▶️ Support our mission by shopping at the Health Ranger Store - https://www.healthrangerstore.com ▶️ Check out exclusive deals and special offers at https://rangerdeals.com ▶️ Sign up for our newsletter to stay informed: https://www.naturalnews.com/Readerregistration.html Watch more exclusive videos here:
Our 245th episode with a summary and discussion of last week's big AI news!Recorded on 05/13/2026Hosted by Andrey Kurenkov and Jeremie HarrisFeel free to email us your questions and feedback at andreyvkurenkov@gmail.com and/or hello@gladstone.aiRead out our text newsletter and comment on the podcast at https://lastweekin.ai/In this episode:OpenAI released new voice intelligence API features including GPT Realtime 2 (GPT-5-powered) plus realtime translation and Whisper transcription, emphasizing the latency–reasoning tradeoff, larger context, and new guardrails amid fraud risks.Thinking Machines previewed a low-latency, full‑duplex conversational system with a two-model architecture and custom inference stack, reporting strong interactivity benchmark results but without public access or third‑party validation yet.Anthropic pushed further into vertical products with Claude for Legal and deeper AWS availability, while ongoing ecosystem tension grows as platform model providers compete with application-layer companies.Safety, policy, and research updates included OpenAI's self-harm trusted contact feature, Anthropic work on reducing agent misalignment by training ethical “why” reasoning, OpenAI's investigation of accidental chain-of-thought grading in RL, and Meta horizon eval updates showing benchmarking limits for long task horizons.Timestamps:(00:00:10) Intro / Banter(00:01:35) Response to listener comments(00:03:27) Sponsor Break Tools & Apps(00:06:27) OpenAI launches new voice intelligence features in its API | TechCrunch(00:15:52) Thinking Machines drops a new, highly responsive model designed for humanlike interactions in real time - SiliconANGLE(00:27:49) Claude For Legal Launches, May Reshape the Legal Tech World – Artificial Lawyer(00:40:27) Threads tests a Meta AI integration that works similarly to Grok | TechCrunch(00:43:08) Google brings agentic AI and vibe-coded widgets to Android | TechCrunch(00:45:33) Google updates AI search to include quotes from Reddit and other sources | TechCrunch Applications & Business(00:47:38) Sam Altman was winning on the stand, but it might not be enough | The Verge(00:55:04) Nvidia C.E.O. Jensen Huang Hitches Ride With Trump to China After Last-Minute Invite - The New York Times(00:58:40) AWS expands Anthropic partnership with Claude Platform launch(01:01:13) Chinese grey market sells Claude API access at 90% off by using stolen credentials, model substitution, and harvesting users' prompts and outputs for resale as AI training data — 'transfer stations' operate through proxy networks that harvest user data(01:06:43) DeepMind Spinout Isomorphic Labs Raises $2.1 Billion to Design Drugs With AI - BloombergProjects & Open Source(01:09:04) Petri: Anthropic Hands Its Alignment Toolbox to Meridian Labs with 3.0 Update(01:12:25) Daybreak': OpenAI's Answer to Anthropic's Project Glasswing Has ArrivedPolicy & Safety(01:14:04) Teaching Claude why(01:21:45) Import AI 455: Automating AI Research(01:28:31) ChatGPT's New Safety Feature Could Alert 'Trusted Contact' to Risk of Self-Harm - CNET(01:30:09) Investigating the consequences of accidentally grading CoT during RL(01:34:46) Natural Language Autoencoders criticism(01:39:15) Review of the "Risks from automated R&D" section in the Anthropic Risk Report (February 2026)Synthetic Media & Art(01:43:39) George Clooney, Tom Hanks, and Meryl Streep back new ‘Human Consent Standard' for AI licensing | The VergeResearch & Advancements(01:45:10) METR says Claude Mythos is testing the limits of AI evaluation – Startup FortuneSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Lisa Liu is the Corporate Marketing & Communications Manager at Stellar Cyber. In this episode, she joins host Charlie Osborne to discuss the future of AI in cybersecurity, including challenges, its differences from other industries, advancements, and more. This episode is brought to you by Stellar Cyber. Learn more about our sponsor at https://StellarCyber.ai.
In this episode of The Brainstorm, Brett, Frank and Sam explore the groundbreaking deal between SpaceX and Anthropic, focusing on the implications for AI compute infrastructure, space-based data centers, and the economics behind data centers. Key Points From This Episode:Economic Value of Space-Based AI: The true value lies in scarcity and speed to market rather than cost savings. Companies prioritize immediate access to space-based compute for strategic advantages.Advancements in Hardware Efficiency: Progress in chips and models is driving revenue growth and expanding margins across the AI stack, allowing profitable growth even with capital constraints.Vertical Integration for Rapid Deployment: Controlling chip fabrication and manufacturing accelerates deployment timelines, providing a competitive edge in scaling AI infrastructure quickly.If you know ARK, you know we focus on long-term innovation. But that doesn't mean we ignore breaking news. Every day, we debate the latest developments in tech and markets. Now, we're bringing those conversations to you in “The Brainstorm,” a co-production from ARK, WOLF, and Public. Tune in weekly for our quick takes on what's shaping innovation right now.Learn more about WOLF: https://wolf.financialLearn more about Public: https://public.com/Disclosure: http://arkinv.st/39rzF94
Until a few months ago, open source AI was kinda a hobby project. Now, it's tearing corporate boardrooms apart. Why? Over the past 6ish months, the gap between frontier closed AI and open sourced AI has shrunk to pretty much nothing. And with the surge of always on agents driving open models, their development and release schedule is on pace with the frontier labs. So if your team isn't paying attention to -- and running test cases through -- open AI models, there's a good chance you'll either be overpaying or playing catch up soon. We walk you through the 101 and what you need to know when it comes to open source AI in this Start Here Series special. Newsletter: Sign up for our free daily newsletterMore on this Episode: Episode PageToday's Episode on LinkedIn: Thoughts on this? Join the convo on LinkedIn and connect with other AI leaders.Upcoming Episodes: Check out the upcoming Everyday AI Livestream lineupWebsite: YourEverydayAI.comEmail The Show: info@youreverydayai.comConnect with Jordan on LinkedInTopics Covered in This Episode:Open Source AI vs Closed Models ShiftChinese Model Distillation & Legal ImpactsEnterprise AI Cost Triage StrategiesGoogle Gemma 4 Local Model CapabilitiesFrontier Model Performance Gap Closing24/7 Agentic AI Systems OverviewAPI Pricing War: DeepSeek vs US VendorsLegal Protection Tradeoffs for Open Source AIAI Workflow Triage: Task-Specific ModelsFuture Trends: Local and Specialized LLMsTimestamps:00:00 Introducing the Firefly AI assistant03:33 Open source AI cost benefits09:25 AI model performance differences10:19 Open source model improvements15:28 Advancements in local AI capabilities17:04 Impact of Google's Gemma four22:15 Introducing Adobe's Firefly AI Assistant24:19 Adobe Firefly AI assistant beta launch29:26 Choosing the right AI tools32:00 Shifting workloads to open source33:31 Using open-source and closed models36:47 The future of open modelsKeywords: open source AI, open source models, local AI models, local models, closed source AI, closed models, proprietary AI, proprietary models, AI agents, agentic AI, AI workflow triage, cheap API, AI API costs, model distillation, Chinese open source models, China AI models, US AI models,Send Everyday AI and Jordan a text message. (We can't reply back unless you leave contact info)
Our 244th episode with a summary and discussion of last week's big AI news!Recorded on 05/08/2026Hosted by Andrey Kurenkov and Jeremie HarrisFeel free to email us your questions and feedback at andreyvkurenkov@gmail.com and/or hello@gladstone.aiRead out our text newsletter and comment on the podcast at https://lastweekin.ai/In this episode:OpenAI released GPT-5.5 Instant as ChatGPT's new default model, showing large benchmark gains and crossing a “high” cyber-risk threshold under its preparedness framework, while bio-safety results were mixed.OpenAI investigated and patched ChatGPT's “goblin” obsession, attributing it to reinforcement-learning rewards that over-amplified playful creature metaphors in a nerdy persona that later bled across versions.Major industry moves included xAI's Grok 4.3 price cuts and voice tools, Mistral's unified Medium 3.5 model and Work mode, and Anthropic's managed-agent upgrades alongside a surprise SpaceX compute deal and reports of a much higher Anthropic valuation.Key policy and security developments covered the Musk–OpenAI trial details, Pentagon AI deployments on classified networks, expanded U.S. government pre-release model reviews, and reports of NSA testing Anthropic's Mythos on Microsoft software.Timestamps:(00:00:10) Intro / Banter(00:01:14) News Preview(00:04:39) Response to listener commentsTools & Apps(00:13:40) OpenAI releases GPT-5.5 Instant, a new default model for ChatGPT | TechCrunch(00:18:23) ChatGPT Became So Obsessed With Goblins That OpenAI Had to Intervene(00:27:14) xAI launches Grok 4.3 at an aggressively low price and a new, fast, powerful voice cloning suite | VentureBeat(00:33:49) Mistral's new flagship Medium 3.5 folds chat, reasoning, and code into one model(00:39:28) Anthropic updates Claude Managed Agents with three new features - 9to5Mac(00:43:42) ElevenLabs Revamps AI Music Platform as Fan-Focused ServiceApplications & Business(00:44:57) A diary, a threat, and a $30 billion stake: What the Musk vs OpenAI trial has actually shown in its first week - The Times of India(00:55:28) Anthropic, SpaceX Sign Deal to Boost AI Computing Power for Claude Software - Bloomberg(01:01:48) Anthropic in talks with investors to raise funds at $900 billion valuation, higher than OpenAI(01:02:37) Anthropic and OpenAI are both launching joint ventures for enterprise AI services | TechCrunch(01:06:15) Anthropic and FIS Are Building an AI Agent to Help Banks Police Financial Crimes(01:07:02) AMD's revenue jumps 38 percent from last year as Q1 data center sales hit $5.8 billion. | The Verge(01:08:51) Banks seek to offload risk to avoid ‘choking' on data centre debt(01:14:08) DeepSeek could be valued at up to $50 billion in first fundraising, sources say | ReutersProjects & Open Source(01:16:14) Natural Language Autoencoders Produce Unsupervised Explanations of LLM Activations(01:22:23) OpenAI just open-sourced its data center networking technologyPolicy & Safety(01:25:02) Pentagon inks deals with Nvidia, Microsoft, and AWS to deploy AI on classified networks | TechCrunch(01:27:27) Google, Microsoft, and xAI will allow the US government to review their new AI models | The Verge(01:32:11) NSA Testing Anthropic's Mythos to Find Flaws in Microsoft Tech(01:35:42) Introspection Adapters: Training LLMs to Report Their Learned BehaviorsResearch & Advancements(01:41:18) Recursive Multi-Agent Systems(01:51:47) Frontier Coding Agents Can Now Implement an AlphaZero Self-Play Machine Learning Pipeline For Connect Four That Performs Comparably to an External SolverSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today's episode delves into a range of significant industry updates, spotlighting scientific advancements, regulatory challenges, and strategic movements that are shaping the future of drug development and patient care. The pharmaceutical landscape is often marked by rapid changes, as evidenced by recent reports indicating President Donald Trump's plan to dismiss FDA Commissioner Marty Makary. This potential leadership change is set against a backdrop of controversies during Makary's tenure, including the rejection of Replimune's advanced melanoma therapy, RP1. This therapy was designed as an oncolytic immunotherapy using a genetically modified herpes simplex virus to target and destroy cancer cells. The FDA's rejection of RP1 ignited debate over the agency's decision-making processes, which some critics view as inconsistent and lacking transparency. Such decisions can have profound implications—delaying patient access to critical treatments and affecting company financials and market dynamics. Furthermore, internal discord at the FDA during Makary's leadership period underscores the importance of stable leadership in maintaining efficiency and fostering scientific rigor. Turning to corporate developments, Gilead Sciences has revised its first-year sales forecast for YezTugo, its long-acting PrEP injection for HIV prevention. The company now projects revenues to reach $1 billion, reflecting strong market uptake. This adjustment highlights the growing demand for innovative PrEP solutions as part of broader HIV prevention strategies. Meanwhile, Daiichi Sankyo is grappling with a $610 million profit setback due to an overextension in their manufacturing capabilities for antibody-drug conjugates (ADCs). This situation illustrates the financial risks inherent in scaling production within rapidly evolving therapeutic areas like ADCs, where balancing supply and demand remains critical. In legal news, Capricor Therapeutics has initiated a lawsuit against NS Pharma concerning a breach-of-contract over Deramiocel, a Duchenne muscular dystrophy treatment. With an FDA decision pending, this legal battle underscores the complexities of partnerships and contract compliance in advancing neuromuscular therapies. On the regulatory front, Biogen and Eisai are experiencing delays from the FDA regarding their Alzheimer's drug Leqembi. These regulatory hurdles highlight the complex processes that can impact drug rollout timelines significantly. Odyssey Therapeutics' successful $304 million IPO aims to bolster its autoimmune and inflammatory disease pipeline. This reflects robust investor interest in biotech firms with promising therapeutic candidates addressing high-need areas. In terms of market dynamics, the competition between Novo Nordisk's Wegovy pill and Eli Lilly's Foundayo is reshaping the oral GLP-1 receptor agonist market. A newly launched weekly tracker will monitor prescription trends to provide insights into how these weight-loss solutions are impacting obesity management. Additionally, Johnson & Johnson's efforts to enhance awareness around depression treatment through public health campaigns illustrate how companies are addressing mental health challenges. Advancements in digital health continue with Tether's rollout of medical AI for mobile devices and MedAptus' operational 'command center,' highlighting ongoing innovations poised to transform healthcare delivery by enhancing efficiency and patient engagement. Strategic acquisitions remain a key theme as Angelini Pharma acquires Catalyst Pharmaceuticals for $4.1 billion—a move that expands Angelini's footprint into the U.S. rare neurological drug market. Similarly, Blackstone's $250 million investment in Anagram Therapeutics for cystic fibrosis enzyme replacement therapySupport the show
Welcome to The Turf Zone podcast. This episode features the article “Minimizing Spring Dead Spot” written by M. Aaron Tucker, Assistant Professor, Auburn University and Wendell J. Hutchens, Assistant Professor, University of Arkansas. Introduction Spring Dead Spot (SDS) is one of the most persistent and damaging diseases affecting warm-season turfgrasses that undergo winter dormancy. First documented in 1954 on a bermudagrass lawn in Stillwater, Oklahoma, SDS continues to challenge turf managers across the southern and transition zone of the United States (Wadsworth & Young, 1960; Tredway, 2009). This article outlines the biology of the disease, key infection periods, and the latest cultural and chemical strategies for effective management. Pathogen Biology SDS is caused by soil-borne fungi in the genus Ophiosphaerella, specifically O. herpotricha, O. korrae, and O. narmari. These pathogens differ in geographic distribution and turfgrass host preference. In Alabama, O. korrae is likely the most prevalent species (Hutchens et al., 2025). Disease Cycle and Symptoms The fungi that cause Spring Dead Spot are ectotrophic root-infecting pathogens, colonizing the outer surfaces of roots, rhizomes, and stolons, leading to necrosis. This damage predisposes turfgrass to winter injury, with symptoms emerging in spring due to the combined effects of fall infection and harsh winter conditions. SDS is a monocyclic disease, with a single infection cycle per year. Infection occurs in late summer to early fall, when evening temperatures cool and soil temperatures drop consistently below 70°F. Symptoms appear in spring as circular or semi-circular patches of dead turf, ranging from six inches to several feet in diameter. Severe outbreaks can result in large, coalesced areas of turf loss, with recovery taking two to three months after green-up—making proactive management essential. Cultural Management Strategies Effective cultural management hinges on understanding the disease's biology. Thatch and organic matter serve as reservoirs for pathogen survival. Practices such as core aerification, verticutting, and fraze mowing during the summer remove thatch and dilute organic matter, thereby reducing inoculum and mitigating spring symptoms (Hutchens et al., 2025). Conversely, cultural practices such as verticutting and aerification on symptomatic turf in spring can actually hinder recovery. Mechanical stress on already damaged turf slows regrowth, so spring cultivation should be avoided. Proper fertilization, particularly nitrogen applications in late summer/fall and spring, supports plant health and recovery (Tredway, 2021; Hutchens et al., 2022). Ammonium sulfate has shown efficacy against O. herpotricha, while calcium nitrate is more effective against O. korrae—highlighting the importance of pathogen identification (Tredway, 2021). Chemical Management Strategies Chemical control with fungicides is most effective when timed correctly. Applications should occur during fall as soil temperatures drop consistently between 65-55°F. Current research is refining this window using the Battaglia-Hutchens cooling degree-day model to optimize timing (Battaglia et al., 2024). The modern demethylation-inhibiting (DMI) fungicide mefentrifluconazole offers strong SDS suppression, while older DMIs like propiconazole and tebuconazole provide moderate efficacy (Clarke et al., 2020). Select succinate dehydrogenase-inhibiting (SDHI) fungicides—like isofetamid, penthiopyrad, and pydiflumetofen—also provide excellent control but carry a higher risk of resistance. Rotating SDHIs with DMIs is recommended to preserve efficacy. Precision Application Technologies Advancements in GPS-guided sprayers allow for targeted fungicide applications. Mapping disease areas in spring and early summer enables precise fall fungicide treatments, reducing both cost and environmental impact (Booth et al., 2021; Henderson et al., 2025). Conclusion Understanding pathogen biology, the disease cycle, and optimal application timing is essential for managing SDS. Continued research is uncovering pathogen-specific responses to cultural and chemical strategies, offering promising avenues for more refined and effective control. Literature Cited Battaglia, M., Hutchens, W. J., & Roberson, T. (2024, November). Development of a Fungicide Application Timing Model for Spring Dead Spot Using Cooling Degree-Days. In ASA, CSSA, SSSA International Annual Meeting. ASA-CSSA-SSSA. Booth, J. C., Sullivan, D., Askew, S. A., Kochersberger, K., & McCall, D. S. (2021). Investigating targeted spring dead spot management via aerial mapping and precision-guided fungicide applications. Crop Science, 61(5), 3134-3144. Clarke, B. B., Vincelli, P., Koch, P., & Chou, M. Y. (2020). Chemical control of turfgrass diseases 2024. Henderson, C., Haak, D., Mehl, H., Shafian, S., & McCall, D. (2025). Precision mapping and treatment of spring dead spot in bermudagrass using unmanned aerial vehicles and global navigation satellite systems sprayer technology. Precision Agriculture, 26(2), 38. Hutchens, W. J., Booth, J. C., Goatley, J. M., & McCall, D. S. (2022). Cultivation and Fertility Practices Influence Hybrid Bermudagrass Recovery from Spring Dead Spot Damage. HortScience, 57(2), 332-336. Hutchens, W. J., Anders, J. K., Butler, E. L., Kerns, J. P., McCall, D. S., Miller, G. L., & Walker, N. R. (2025). Fifteen years of findings: Advancements in spring dead spot research from 2009 to 2024. Crop Science, 65(1), e21367. Tredway, L. P., Tomaso-Peterson, M., Perry, H., & Walker, N. R. (2009). Spring dead spot of bermudagrass: A challenge for researchers and turfgrass managers. Plant Health Progress, 10(1), 32. Tredway, L. P., Soika, M. D., Butler, E. L., & Kerns, J. P. (2021). Impact of nitrogen source, fall fertilizers, and preventive fungicides on spring dead spot caused by Ophiosphaerella korrae and O. herpotricha. Crop Science, 61(5), 3187-3196. Wadsworth, D. F., & Young, H. C. (1960). Spring dead spot of bermudagrass. Plant Dis. Rep, 44, 516-518. You have been listening to The Turf Zone Podcast. Follow The Turf Zone on X, Facebook and LinkedIn for all things turfgrass, featuring podcasts, magazines, events and more. Visit www.theturfzone.com for more. The post Minimizing Spring Dead Spot appeared first on The Turf Zone.
Our 243rd episode with a summary and discussion of last week's big AI news!Recorded on 04/29/2026Hosted by Andrey Kurenkov and Jeremie HarrisFeel free to email us your questions and feedback at andreyvkurenkov@gmail.com and/or hello@gladstone.aiRead out our text newsletter and comment on the podcast at https://lastweekin.ai/In this episode:OpenAI released GPT-5.5 with strong coding-oriented improvements, a system card discussing chain-of-thought monitorability and misalignment testing, higher pricing than GPT-5.4, and notable quirks like a system-prompt warning about “goblins.”xAI launched Grok Voice Think Fast 1.0, claiming large benchmark leads for real-time voice agents and reporting major Starlink customer-support automation and sales conversion impact.DeepSeek open-sourced DeepSeek V4 (Pro and Flash) featuring MoE scaling and 1M-token context via hybrid/compressed attention changes, while Tencent released Hunyuan 3 preview with weaker benchmark performance; a new long-horizon agent benchmark (Clawmark) shows low task success rates.Major business, legal, and policy updates include Google's planned up-to-$40B investment and 5GW compute commitment to Anthropic, Meta's AWS Gravitron deal and China blocking Meta's Manus acquisition, a revamped OpenAI–Microsoft agreement, ongoing Musk–OpenAI trial developments, and new safety/security research on sabotage, document degradation under delegation, and bit-flip attacks.Timestamps:(00:00:10) Intro / Banter(00:02:00) News Preview(00:02:26) Response to listener comments(00:02:55) SponsorsTools & Apps(00:05:55) OpenAI Unveils Its New, More Powerful GPT-5.5 Model - The New York Times(00:23:33) xAI Launches grok-voice-think-fast-1.0: Topping τ-voice Bench at 67.3%, Outperforming Gemini, GPT Realtime, and More - MarkTechPost(00:29:00) Claude can now plug directly into Photoshop, Blender, and Ableton | The VergeProjects & Open Source(00:29:38) China's DeepSeek releases preview of long-awaited V4 model as AI race intensifies(00:47:05) Tencent Unveils Hy3 preview; Model Enhances Agent Capabilities and Real-World Usability - Tencent 腾讯(00:50:14) ClawMark: A Living-World Benchmark for Multi-Turn, Multi-Day, Multimodal Coworker AgentsApplications & Business(00:53:03) Google Plans to Invest Up to $40 Billion in Anthropic(00:56:26) Meta will use hundreds of thousands of AWS Graviton chips(00:59:51) China blocks Meta's $2 billion takeover of AI startup Manus(01:01:45) OpenAI shakes up partnership with Microsoft, capping revenue share payments(01:07:13) Elon Musk Testifies of AI Risk at Trial, Says OpenAI Tried to ‘Steal' a Charity - WSJ(01:11:50) Judge rejects DOJ bid to delay Anthropic appeal in Pentagon dispute(01:14:42) Google's Gemini can now run on a single air-gapped server — and vanish when you pull the plug(01:19:07) DeepMind's David Silver just raised $1.1B to build an AI that learns without human data | TechCrunchPolicy & Safety(01:22:47) Evaluating whether AI models would sabotage AI safety research(01:28:59) LLMs Corrupt Your Documents When You Delegate(01:32:50) Temporal Sparse Autoencoders: Leveraging the Sequential Nature of Language for Interpretability(01:39:53) Memorandum on Adversarial Distillation of American AI Models(01:41:41) Teen boys are dating their AI chatbots—and experts warn it could kill their careers | Fortune(01:43:57) Announcing the Anthropic Economic Index Survey(01:45:21) Scoop: CISA lacks access to Anthropic's MythosSynthetic Media & Art(01:48:03) Taylor Swift Files to Trademark Voice and Likeness to Protect Against AI MisuseResearch & Advancements(01:49:15) Maximal Brain Damage Without Data or Optimization: Disrupting Neural Networks via Sign-Bit FlipsSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
"Not a creative"?
Our 242nd episode with a summary and discussion of last week's big AI news!Recorded on 04/22/2026Hosted by Andrey Kurenkov and Jeremie HarrisFeel free to email us your questions and feedback at andreyvkurenkov@gmail.com and/or hello@gladstone.aiRead out our text newsletter and comment on the podcast at https://lastweekin.ai/In this episode:OpenAI released a new ChatGPT image model that excels at accurate text and screenshot-like generations, suggesting a transformer-style approach aligned with agentic “computer use” ambitions.Chinese model activity accelerated with Alibaba's Qwen 3.6 Max Preview moving to an API-only offering, plus open releases from Moonshot AI (Kimi K2.6, a 1T-parameter MoE) and Minimax (Minimax M 2.7) showing strong benchmark results.Google expanded Deep Research with a “Max” option built on Gemini 3.1 Pro and MCP support for accessing proprietary data, while Mozilla reported using Anthropic's Claude to find and fix 271 Firefox bugs. Business and policy updates include a reported SpaceX–Cursor deal with a $60B buy option, Cerebras filing for an IPO, Amazon adding $5B to Anthropic alongside a $100B AWS spending pledge, and platform responses to synthetic media like AI music spam and YouTube deepfake takedown requests.Timestamps:(00:00:10) Intro / Banter(00:01:05) News Preview(00:01:41) Sponsors(00:04:41) Response to listener commentsTools & Apps(00:09:40) ChatGPT's new Images 2.0 model is surprisingly good at generating text | TechCrunch(00:16:02) Alibaba Drops Qwen 3.6 Max Preview—Its Most Powerful Model Yet - Decrypt(00:19:26) Google launches Deep Research and Deep Research Max agents to automate complex research(00:25:00) Mozilla Used Anthropic's Mythos to Find and Fix 271 Bugs in Firefox | WIRED(00:28:35) Ordering with the Starbucks ChatGPT app was a true coffee nightmare | The VergeApplications & Business(00:29:48) SpaceX is working with Cursor and has an option to buy the startup for $60B | TechCrunch(00:34:11) AI chip startup Cerebras files for IPO | TechCrunch(00:38:23) Two startups want to replace how AI learns: one just raised $180M, another is seeking up to $1B(00:38:56) Months-old start-up Recursive Superintelligence raises $500mn for self-teaching AI(00:41:36) Anthropic takes $5B from Amazon and pledges $100B in cloud spending in return | TechCrunch(00:45:09) Kevin Weil and Bill Peebles exit OpenAI as company continues to shed 'side quests' | TechCrunch(00:46:04) Meta hires five Thinking Machines Lab founders including a reported $1.5 billion engineer - Meta cuts 198 Bay Area jobs as even larger layoffs reportedly loom(00:50:12) Meta employees are up in arms over a mandatory program to train AI on their mouse movements and keystrokes(00:51:43) Chinese fabs import record volumes of US chipmaking equipment via Singapore and Malaysia — homegrown tool makers booked record 2025 revenues as price competition squeezes margins(00:54:01) Google Eyes New Chips to Speed Up AI Results, Challenging Nvidia(00:54:20) Canadian quantum company Xanadu soars to $16 billion valuation after Nvidia releaseProjects & Open Source(01:00:13) Moonshot AI releases Kimi-K2.6 model with 1T parameters, attention optimizations - SiliconANGLE(01:05:22) MiniMax Just Open Sourced MiniMax M2.7: A Self-Evolving Agent Model that Scores 56.22% on SWE-Pro and 57.0% on Terminal Bench 2 - MarkTechPostPolicy & Safety(01:06:25) Infusion: Shaping Model Behavior by Editing Training Data via Influence Functions(01:10:25) Scoop: NSA using Anthropic's Mythos despite blacklist(01:11:03) Unauthorized group has gained access to Anthropic's exclusive cyber tool Mythos, report claimsResearch & Advancements(01:17:21) Parcae: Scaling Laws For Stable Looped Language Models(01:24:20) OccuBench: Evaluating AI Agents on Real-World Professional Tasks via Language Environment SimulationSynthetic Media & Art(01:27:01) Deezer says 44% of songs uploaded to its platform daily are AI-generated | TechCrunch(01:29:47) Celebrities will be able to find and request removal of AI deepfakes on YouTube | The VergeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Tomer and Winnipeg find themselves... someplace else.Episode 17 Transcript link (coming soon)Crash of the Mellifera: Employee Q&A form can be found here!Follow us on: tumblr at melliferacrash.tumblr.com bluesky at mellifera-crash.bsky.socialmastodon at mellifera_crashDonations can be sent to Morgan's ko-fi page at ko-fi.com/morganlanewrites. Check out Morgan's other projects at morganlanewrites.com.Various sound effects and music obtained from freesound.org. All other songs and effects provided either by Sam Kitsch or Morgan Lane. Thank you to the following freesound artists: barkerspinheadtsakanemashabaeduardvlogicedphoenix49lyrislitej1987bulbastregiddsterstu556SheyvanShadowReaper2814dynamiquekylesJakLockenewlocknewforthehorde68RavenWolfProdsRico_CassazacoosemekKat7777wlabarronOverlookHotelRecordsMootMcNoodlesthomasanthony321jorickhoofdgis_swedenSilverDubloonsTreblofangWarrick_Lendonthemfishi_luv_soundzdeleted_user_7146007RepDac3mhtaylor67slooshie_96kgopongRutgerMullerEelkeferdingererokiakygarlicfillmat
Stay informed on current events, visit www.NaturalNews.com - Trump's False Claims and Iran's Response (0:12) - Economic Impact of Oil Supply Reduction (2:51) - Iran's Strategic Moves and Trump's Escalation (8:55) - Trump's Mental State and Military Commanders' Concerns (12:31) - Potential Political and Military Coups (18:59) - Economic and Social Implications of the Conflict (26:23) - Preparation and Self-Reliance (29:23) - The Role of Space Technology (1:12:03) - The Future of Energy and Transportation (1:21:40) - Government Policies and EV Market Disruptions (1:23:12) - Advancements in Battery Technology (1:26:24) - Interest in Off-Grid Storage Solutions (1:29:08) - Challenges with Solar System Installation and Maintenance (1:30:38) - Preparing for the End of Affordable Energy (1:32:33) Watch more independent videos at http://www.brighteon.com/channel/hrreport ▶️ Support our mission by shopping at the Health Ranger Store - https://www.healthrangerstore.com ▶️ Check out exclusive deals and special offers at https://rangerdeals.com ▶️ Sign up for our newsletter to stay informed: https://www.naturalnews.com/Readerregistration.html Watch more exclusive videos here:
This episode is dedicated to the memory of Dr. Al Yuzpe, a true pioneer in reproductive medicine.This episode (recorded in 2023) explores the evolution and future of IVF with leading Canadian reproductive endocrinologist Dr. Al Yuzpe. He reflects on 50 years of fertility advancements, including his role in developing Clomiphene and pioneering laparoscopic surgery in Canada.The conversation also dives into how reproductive medicine has transformed from its early beginnings into a groundbreaking field that has helped countless couples achieve parenthood. Dr. Yuzpe shares his passion for the field and discusses how emerging technologies, including artificial intelligence, are improving IVF outcomes and shaping the next generation of fertility care.Key Topics:Dr. Al Yuzpe's pioneering contributions to reproductive medicine, including the development of Clomiphene and early adoption of laparoscopic surgery in Canada. Key ovulation induction options (Clomiphene, Letrozole, FSH, HCG), including their effectiveness, differences, and potential side effects. Advances in IVF techniques, such as embryo selection (Day 3 vs. blastocyst), genetic screening, and egg freezing for fertility preservation. The growing role of integrative care—including acupuncture and whole-body preparation—in improving IVF outcomes. The future of fertility, highlighting artificial intelligence in evaluating eggs, sperm, and embryos, and ongoing innovations in embryo testing and lab technologies. Dr. Albert Yuzpe's Bio: Dr. Al Yuzpe is one of Canada's most distinguished reproductive endocrinologists, with over four decades of experience in infertility care and more than 30 years in IVF. He is co-founder and co-director of Olive Fertility Centre and previously founded Genesis Fertility Centre in Vancouver. Trained at Western University, where he later became a full professor and now holds the title of Emeritus Professor, his early research focused on fertility medications such as clomiphene and gonadotropins.He has received numerous national awards recognizing his contributions to reproductive medicine and women's health. Dr. Yuzpe is also widely known for pioneering the emergency contraceptive pill, known as the “Yuzpe method,” considered one of the most impactful Canadian health discoveries of the past century.
“Every single lifestyle choice we make can either drive inflammation up or drive it down.” Cynthia Thurlow, NP, is a perimenopause and menopause expert, nutrition educator, and nurse practitioner with nearly 20 years of experience in the ER and clinical cardiology. Now, she works to help women live vibrant and healthy lives. Her new book, the Menopause Gut, comes out on April 28. This podcast was created in partnership with CocoaVia. Their 500 mg Cocoa Flavanols Capsules and Powder include the most studied and clinically proven extract in the market—at levels shown to support cardiovascular health.* Use code MBG2026 for 20% at cocoavia.com. Valid on all products: Single, bulk, or subscription of CocoaVia excluding stick packs. New customers only. 00:00 - Why women chronically undereat protein 03:19 - Fiber: the missing link in gut health 09:00 - Healthy fats & targeted nutrients 13:08 - The importance of healthy blood flow 17:52 - 5 metabolic markers you need to track 21:47 - The Boston Heart test 26:19 - The genetic aspect of cholesterol 28:50 - Advancements in cardio testing 33:25 - AI in medicine 35:17 - Hormones, inflammation, & your diet 39:42 - Discussing her new book You can find Thurlow at her website: https://www.cynthiathurlow.com/ And get her new book, The Menopause Gut, here: https://a.co/d/01BKJHc8 We hope you enjoy this episode, and feel free to watch the full video on YouTube! Whether it's an article or podcast, we want to know what we can do to help here at mindbodygreen. Let us know at: podcast@mindbodygreen.com. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Learn more about your ad choices. Visit megaphone.fm/adchoices
Host: Darryl S. Chutka, M.D. Guest: Forrest Sturgill, M.D. Parkinson's Disease is a relatively common neurodegenerative disorder characterized by motor symptoms such as bradykinesia, rigidity and resting tremor, as well as non-motor symptoms such as autonomic dysfunction, mood disorders and cognitive changes. The diagnosis is established with a medical history and physical exam. Parkinson's is truly a disorder where the neurologist needs to work with the primary care clinician to provide optimal care of the patient. What are the typical presenting symptoms of Parkinson's? Is an urgent referral to a neurologist necessary? When should pharmacologic treatment be started? The topic for this podcast is “Advancements in the Diagnosis and Treatment of Parkinson's Disease” and these are some of the questions I'll be asking my guest, Dr. Forrest Sturgill, a neurologist in the Department of Neurology at the Mayo Clinic. Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development
How does one man's dedication to community health reshape cancer prevention efforts in Texas? Carlton Allen's passion for public health and population health, sparked during his academic years, led him to an influential role in the Cancer Prevention and Research Institute of Texas (CPRIT). Through his guidance, CPRIT addresses significant cancer burdens and health disparities statewide. Meanwhile, Allen champions the Texas Cancer Plan as a comprehensive roadmap for continued progress in cancer prevention and care. Key Questions Answered 1. How did Carlton Allen get into public health? 2. What differentiates public health from direct patient care according to Carlton? 3. Where did Carlton Allen complete his education? 4. How did Carlton Allen integrate community health workers (CHWs) into clinical operations? 5. What are the challenges in obtaining funding for community health workers? 6. What is the Cancer Prevention Research Institute of Texas (CPRIT) and what roles does it play? 7. How does CPRIT impact cancer prevention and research in Texas? 8. What frustrations does Carlton Allen face in his role at CPRIT? 9. What was Carlton Allen’s role in the Texas Cancer Plan? 10. What values does Carlton hope to instill in his children based on his community work? Timestamped Overview 00:00 Community Health Workers' Impact 03:42 Healthcare Worker Reimbursement Challenge 07:46 Expanding Healthcare Outreach with Grants 10:07 Visiting Texas Prevention Grantees 13:27 Advancements in Cancer Prevention 16:51 Cancer Secrecy in Males 21:14 Inclusive Cancer Care Guidelines 25:57 Community Engagement and Volunteerism 27:56 Raising Hardworking, Community-Minded Children Learn more about CPRIT here. Support The Rose HERE. Subscribe to Let’s Talk About Your Breasts on Apple Podcasts, Spotify, iHeart, and wherever you get your podcasts.See omnystudio.com/listener for privacy information.
Viv Govender of FirstRand discusses how investment decisions in AI infrastructure are shaping competitive positioning across the industry.
The 1982 murder of 15-year-old Linda Strait was a cold case for more than 20 years. Advancements in DNA technology finally led Spokane Police to the teen's killer - Arbie Williams. Williams was already serving time for a separate case when detectives finally linked him to Linda's murder.That case involved the kidnapping of two eight-year-old little girls outside of their Spokane Valley elementary school. An arrest and sentencing for Linda's case gave her loved ones a level of peace that they say is continually disrupted as he comes up for parole.To watch our full Cold Case series, be sure to subscribe to our YouTube channel @NonStopLocalNews and ring the bell to be notified of every new episode, plus daily news updates.
April is Sarcoidosis Awareness Month! Host Patti Tripathi speaks with Mary McGowan, president and CEO of the Foundation for Sarcoidosis Research, about the importance of continuing research on sarcoidosis, advocacy and policy efforts in the field, and fighting for paid leave for those participating in clinical trials. Learn more about the Foundation for Sarcoidosis Research at https://www.stopsarcoidosis.org/ Learn more about The Champions for Change: https://site.thoracic.org/press-releases/champions-for-change-paid-time-off-initiative-just-made-clinical-trials-participation-easier Learn more about the bipartisan Congressional Sarcoidosis Caucus: https://gottheimer.house.gov/posts/release-gottheimer-launches-bipartisan-sarcoidosis-caucus-to-battle-the-debilitating-disease-in-memory-of-his-mother
Manure management isn't just about handling waste anymore—it's about efficiency, nutrient optimization, and maximizing ROI. In this episode, we sit down with Isaac Lemmenes, Product Specialist at Nuhn Industries, to break down how manure equipment is evolving to meet the demands of modern agriculture. With over a century of experience, Nuhn is pushing the limits of what's possible in liquid manure handling—from massive pump capacity to precision nutrient placement. We cover: Next-Level Equipment • The new 908 HP Booster X Lead Pump and what it's capable of • Pumping systems moving up to 3,000 gallons per minute • Who these high-capacity machines are built for Manure Handling Challenges • Why lagoon systems require constant innovation • Updates to the Lagoon Crawler and real-world performance improvements • The realities of working in extreme manure environments Nutrient Management • Injection systems placing nutrients below the soil surface • Improving efficiency and reducing nutrient loss • How manure is becoming a more precise input Growth & Innovation • Nuhn's 148,000 sq. ft expansion and what it means • How customer feedback drives product development • Where R&D is focused next The Future of Manure Tech • Automation and remote monitoring • Speed vs. efficiency in pumping systems • What manure management could look like in the next 5–10 years Want Farm4Profit Merch? Custom order your favorite items today!https://farmfocused.com/farm-4profit/ Don't forget to like the podcast on all platforms and leave a review where ever you listen! Website: www.Farm4Profit.comShareable episode link: https://intro-to-farm4profit.simplecast.comEmail address: Farm4profitllc@gmail.comCall/Text: 515.207.9640Subscribe to YouTube: https://www.youtube.com/channel/UCSR8c1BrCjNDDI_Acku5XqwFollow us on TikTok: https://www.tiktok.com/@farm4profitllc Connect with us on Facebook: https://www.facebook.com/Farm4ProfitLLC/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Clean lumen club! This week, BackTable meets you at the carotid bifurcation to discuss all things carotid angioplasty and stenting. Interventional neuroradiologist and cerebrovascular surgeon Dr. Adnan Siddiqui, Vice Chairman of the University of Buffalo's Department of Neurosurgery, joins host Dr. Sameh Sayfo to discuss the evolution and current state of carotid disease treatment. --- Get the BackTable app https://www.backtable.com/app --- This podcast is supported by Terumohttps://www.terumois.com/ --- Timestamps 00:00 - Introduction02:48 - From Aspirin to Endarterectomy03:47 - Rise of Carotid Stenting06:46 - CREST-2 and CMS Coverage09:57 - Management of Severe Asymptomatic Carotid Stenosis 15:35 - New Stent Designs Explained17:56 - Five Tips for New Operators20:08 - Case Selection Algorithm22:04 - Learning Curve and Mentorship28:27 - What's Next: IVL and Outpatient31:24 - Managing Complications Safely35:05 - Closing and Credits --- More about this episode Dr. Siddiqui details the history of carotid stenosis treatment, charting its path and progression from medical therapy to endarterectomy and modern stenting approaches. He includes how recent trial data and updated CMS reimbursements have influenced practice and generated recent developments such as second generation stent technology. Dr. Siddiqui shares perspectives on patient selection, operator learning curve, complication preparedness, and the importance of structured training and proctoring as technology and techniques continue to improve. The physicians close by overviewing future directions for the carotid space such as IVL and how to approach management of procedural complications. --- Resources Dr. Adnan Siddiqui provider profilehttps://www.ubns.com/physicians/dr-adnan-h-siddiqui/ Carotid Endarterectomy for Asymptomatic Carotid Stenosis: Asymptomatic Carotid Surgery Trial (ACAS)https://www.ahajournals.org/doi/10.1161/01.str.0000141706.50170.a7 Asymptomatic Carotid Surgery Trial (ACST-2)https://www.acc.org/latest-in-cardiology/clinical-trials/2021/08/25/23/24/acst2 Protected Carotid-Artery Stenting versus Endarterectomy in High-Risk Patients (SAPPHIRE trial)https://www.nejm.org/doi/full/10.1056/NEJMoa040127 Medical Management and Revascularization for Asymptomatic Carotid Stenosis (CREST-2 trial) https://www.nejm.org/doi/full/10.1056/NEJMoa2508800 The North American Symptomatic Carotid Endarterectomy Trial (NASCET trial)https://www.ahajournals.org/doi/10.1161/01.str.30.9.1751
Scientific advancement has always been at the heart of public health, but as new technologies emerge, the opportunities and challenges are evolving. In this National Public Health Week conversation, ASTHO Chief Medical Officer, Dr. Susan Kansagra explores how public health can better integrate innovation into everyday practice, from leveraging continuous improvement frameworks like Plan-Do-Study-Act to building stronger partnerships with academic and research institutions. It's about turning questions from the field into actionable research and using that knowledge to improve real-world outcomes. National Public Health WeekPublic Health Infrastructure Grant: Resources & Impact - PHIGDriving Impact with Flexible Funding
Our 239th episode with a summary and discussion of last week's big AI news!FYI: this one has pretty out of date news, I was traveling last week and failed to upload... apologies. Recorded on 03/25/2026Hosted by Andrey Kurenkov and Jeremie HarrisFeel free to email us your questions and feedback at andreyvkurenkov@gmail.com and/or hello@gladstone.aiRead out our text newsletter and comment on the podcast at https://lastweekin.ai/In this episode:OpenAI is discontinuing the Sora iPhone app and seemingly shutting down its video generation API, while retaining internal video world-modeling work; the move is framed as a compute- and focus-driven pivot toward coding and productivity agents, alongside a collapsed Disney Sora deal. Anthropic's Claude Code/Cowork gains full computer control via keyboard/mouse/display, tied to the recent Cept acquisition, and Google's Gemini rolls out background “task automation” on select phones for limited delivery/ride-share use. Cursor releases the cheaper, benchmark-strong Composer 2 coding model amid controversy over its Kimi-based origins and licensing attribution. Other items include Adobe Firefly custom model training, Luma's Uni 1 image model, US contracting and legislative proposals affecting AI safeguards and state preemption, major chip/memory developments (Meta ASICs with Broadcom, Micron's HBM-driven surge, Musk's “Terra Fab”), robotaxi scaling, and research on monitoring agent misalignment, shutdown resistance, “consciousness cluster” preferences, and self-improving “hyper agents.”Timestamps:(00:00:10) Intro / BanterTools & Apps(00:01:48) OpenAI Discontinues Sora App, Shuts Down Video Generation Service and API - Bloomberg(00:07:12) Anthropic's Claude Code and Cowork can control your computer | The Verge(00:13:15) Gemini task automation is slow, clunky, and super impressive | The Verge(00:19:44) Cursor Launches Composer 2 AI Model to Challenge OpenAI & Anthropic(00:28:28) Adobe's AI image generator can now be trained on your own art | The Verge(00:29:40) Luma AI launches Uni-1, a model that outscores Google and OpenAI while costing up to 30 percent less | VentureBeatApplications & Business(00:32:41) Trump Contracting Clause Would Override AI Safeguards(00:40:00) Meta accelerates AI ASIC roll-out as Broadcom secures four-generation chip design deal(00:47:07) Micron revenue almost triples, tops estimates as demand for memory soars(00:50:54) Elon Musk Unwraps $25 Billion Terafab Chip-Building Project - CNET(00:56:40) Zoox to widen US robotaxi footprint with San Francisco, Vegas expansion(00:57:39) Waymo hits 170 million miles while avoiding serious mayhem | The VergePolicy & Safety(00:58:43) The White House just laid out how it wants to regulate AI | CNN Business(01:06:54) How we monitor internal coding agents for misalignment(01:12:30) Incomplete Tasks Induce Shutdown Resistance in Some Frontier LLMs(01:18:15) Summary: Mechanisms to Verify International Agreements about AI Development(01:23:09) Scoop: Anthropic meets with House Homeland Security behind closed doorsResearch & Advancements(01:24:24) Consciousness Cluster: Preferences of Models that Claim they are Conscious(01:30:22) HyperAgentsSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
"Interventional oncology has really evolved into an important component of modern cancer care and is often described now as the fourth pillar alongside medical, surgical, and radiation oncology. The specialty now encompasses a broad spectrum of image-guided procedures that support from cancer diagnosis, treatment, to effectively managing symptoms that are caused by the disease. In other words, what we're seeing is that across the continuum of care, IO is playing a vital role," ONS member Evelyn P. Wempe, DNP, MBA, APRN, ACNP-BC, AOCNP®, CRN, NEA-BC, executive director for advanced practice providers for the oncology service line at the University of Miami Sylvester Comprehensive Cancer Center in Florida, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about interventional oncology. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0 Earn 0.5 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by April 3, 2027. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge related to interventional oncology as a treatment modality for cancer. Episode Notes Complete this evaluation for free NCPD. ONS Podcast™ episodes: Episode 347: Care Considerations for Radiopharmaceuticals and Theranostics in Patients With Cancer Episode 285: Transarterial Chemoembolization: The Oncology Nurse's Role ONS Voice articles: Advancements in Interventional Oncology Ease Pain and Limit Opioid Use Build Your Confidence in Understanding Vascular IO Procedures From Heat to Cold to Electrical Pulses, Here's How Percutaneous IO Can Preserve Life and Function Interventional Oncology Is an Evolving Subspecialty for Oncology Nurses Clinical Journal of Oncology Nursing articles: Interventional Oncology (December 2025 supplement) Expanding the Scope: The Emergence of Interventional Oncology Nursing The Evolution of Interventional Oncology and the Specialized Role of Oncology Nursing Interventional Oncology Learning Library Interventional Oncology Huddle Card Society of Interventional Oncology Association for Radiologic and Imaging Nursing Society of Interventional Radiology: Cancer resources RadiologyInfo.org (Radiological Society of North America) To discuss the information in this episode with other oncology nurses, visit the ONS Communities. To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "In the 1990s, tumor-focused procedures such as embolization and ablation began to emerge, marking a shift toward oncologic applications. The 2000s saw rapid technologic advancements that expanded the scope and volume of oncology-directed interventions, including vascular access device placement, liver-directed transcatheter therapies for tumor control, and more sophisticated ablation modalities. Today, interventional oncology, or IO, extends beyond procedural work, encompassing comprehensive clinical care through dedicated IO clinics that support patient consultations, treatment planning, and postprocedure follow-up." TS 1:50 "In the immediate postprocedure phase, the IO nurse plays a critical role in patient safety in education, and oftentimes it may not be the same nurse that's caring for the patient in the procedural environment versus the postprocedural environment. But the role is really about continuous need to assess the patient's comfort level, to ensure that there is hemodynamic stability of the patient while closely monitoring for complications such as bleeding at the access site—of course, depending on the procedure—if there's any hematoma formation or changes in vital signs, or if there's any pain that needs to be addressed. Most importantly is maintaining patient safety in that immediate phase after the procedure." TS 8:07 "Before an IO procedure, both teams really must review the patient's clinical status. There has to be a clear understanding of: Is this patient ready to undergo a procedure? Is there any necessary imaging that needs to be done, as well as laboratory review and any systemic treatments, that may affect procedural planning? And oftentimes, in my experience, really, the oncology nurses are the ones really speaking with each other based on what the decision has been from both teams working together and communicating this to the patient." TS 13:49 "I think the oncology nurse needs to assess the patient's baseline understanding of interventional oncology. I often began my visits with a simple, open-ended question, 'Tell me why you're here today.' This allowed me to gauge their knowledge of the specialty and the purpose of the visit with the IO team. And in many cases, patients were unfamiliar with interventional oncology, which meant education needed to start with an explanation of what IO is and how it fits into their cancer care journey. Once that foundation was established, I was then able to introduce information about the specific procedure and its role in their overall treatment plan. And we can work together to establish goals of care and health. Having this approach ensured patients were informed, engaged, and better prepared for the procedure ahead." TS 16:06 "As nurses explore career options, interventional oncology is definitely one to consider. It really unites technology and innovation, and I think that's where we're heading with health care, with so much advancement in research and science. There's definitely a place for oncology nurses in this space, and it would be great to see that continue to flourish." TS 24:23
The approach to AI so far can be best described as a using brute force to make things happen. It's been effective so far, but the approach starts to run into problems when the numbers get really big. Thankfully, some new developments in AI could help alleviate that challenge. Matt, Jon, and Tyler discuss how Google and ARM are advancing AI efficiency. Plus, social media's bad week in court and the mailbag. Tyler Crowe, Jon, Quast, and Matt Frankel discuss: Meta and Alphabet losing watershed social media cases Is a “tobacco moment” as bad as it sounds? Advancements in AI efficiency Mailbag: Auto invest or buy the dip? Companies discussed: GOOG, META, BP, DD, DOW, MMM, ARM, AAPL, MU, SNDK, INTC, NVDA, AMD Got investing questions for the podcast? Email us at podcasts@fool.com Host: Tyler CroweGuests: Matt Frankel, Jon QuastEngineer: Bart Shannon Advertisements are sponsored content and provided for informational purposes only. The Motley Fool and its affiliates (collectively, "TMF") do not endorse, recommend, or verify the accuracy or completeness of the statements made within advertisements. TMF is not involved in the offer, sale, or solicitation of any securities advertised herein and makes no representations regarding the suitability, or risks associated with any investment opportunity presented. Investors should conduct their own due diligence and consult with legal, tax, and financial advisors before making any investment decisions. TMF assumes no responsibility for any losses or damages arising from this advertisement. Learn more about your ad choices. Visit megaphone.fm/adchoices
With the increasing incidence of colorectal cancer in those less than 50 years of age, one must wonder how many patients present with a Stage IV diagnosis. Take a deep dive with us discussing the management of metastatic colorectal cancer by joining our team and guests, Drs. Cathy Eng, Michael D'Angelica, and Nina Sanford.Hosts: - Dr. Janet Alvarez - General Surgery Resident at New York Medical College/Metropolitan Hospital Center- Dr. Wini Zambare – General Surgery Resident at Weill Cornell Medical Center/New York Presbyterian- Dr. Philip Bauer, Assistant Professor of Surgery, Division of Colon and Rectal Surgery, The Ohio State University Wexner Medical Center, Arthur G. James Cancer Hospital- Dr. J. Joshua Smith MD, PhD, Chair, Department of Colon and Rectal Surgery at MD Anderson Cancer Center Guest Speakers:- Dr. Michael D'Angelica MD, FACS – Hepatopancreatobiliary Surgery, Memorial Sloan Kettering Cancer Center, Enid A. Haupt Chair in Surgery, Vice Chair, Education- Dr. Cathy Eng MD, FACP - Division of Hematology and Oncology, Vanderbilt-Ingram Cancer Center, David H. Johnson Endowed Chair in Surgical and Medical Oncology, Professor of Medicine, Hematology and Oncology, VICC Associate Director for Strategic Relations and Research Partnerships, Executive Director, Young Adult Cancers Program - Dr. Nina Sanford, MD – Radiation Oncology, UT Southwestern Medical Center, Chief of Gastrointestinal Radiation Oncology Service, Associate Professor Learning Objectives:1. Review the epidemiology, prognosis, and common metastatic patterns of metastatic colorectal cancer (mCRC).2. Discuss the role of systemic chemotherapy and targeted therapies in the first- and subsequent-line treatment of mCRC, including the impact of molecular biomarkers such as MSI/MMR, RAS, BRAF, and HER2.3. Evaluate the indications and timing of surgical and locoregional therapies for metastatic colorectal cancer, particularly in patients with liver-limited or oligometastatic disease.4. Describe the multidisciplinary management of mCRC, including the roles of radiation therapy, systemic therapy sequencing, and palliative interventions to optimize outcomes and quality of life.References:Singh, M., Morris, V. K., Bandey, I. N., Hong, D. S. & Kopetz, S. Advancements in combining targeted therapy and immunotherapy for colorectal cancer. Trends Cancer 10, 598–609 (2024). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/38821852/Napolitano, S. et al. BRAFV600E mutant metastatic colorectal cancer: Current advances in personalized treatment and future perspectives. Cancer Treat. Rev. 134, (2025). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40009904/Ciardiello, F. et al. Clinical management of metastatic colorectal cancer in the era of precision medicine. CA. Cancer J. Clin. 72, 372–401 (2022). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/35472088/Kim, S. Y. & Kim, T. W. Current challenges in the implementation of precision oncology for the management of metastatic colorectal cancer. ESMO Open 5, e000634 (2020). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/32188714/Biller, L. H. & Schrag, D. Diagnosis and Treatment of Metastatic Colorectal Cancer: A Review. JAMA 325, 669–685 (2021). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/33591350/Smith, J. J. et al. Genomic stratification beyond Ras/B-Raf in colorectal liver metastasis patients treated with hepatic arterial infusion. Cancer Med. 8, 6538–6548 (2019). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/31503397/Saadat, L. V. et al. Hepatic Artery Infusion Chemotherapy Compared to Transarterial Radioembolization For Unresectable Colorectal Liver Metastases. Ann. Surg. 10.1097/SLA.0000000000006851 doi:10.1097/SLA.0000000000006851. PubMed Link: https://pubmed.ncbi.nlm.nih.gov/?term=10.1097/SLA.0000000000006851 (Linked via DOI search as the direct PMID is still indexing)Xiao, A. & Fakih, M. KRAS G12C Inhibitors in the Treatment of Metastatic Colorectal Cancer. Clin. Colorectal Cancer 23, 199–206 (2024). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/38825433/André, T. et al. Pembrolizumab in Microsatellite-Instability–High Advanced Colorectal Cancer. N. Engl. J. Med. 383, 2207–2218 (2020). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/33264544/Morris, V. K. et al. Treatment of Metastatic Colorectal Cancer: ASCO Guideline. J. Clin. Oncol. 41, 678–700 (2023). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/36252154/Xu, Z. et al. Treatments for Stage IV Colon Cancer and Overall Survival. J. Surg. Res. 242, 47–54 (2019). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/31071604/Smith, J. J. & D'Angelica, M. I. Surgical Management of Hepatic Metastases of Colorectal Cancer. Hematol. Oncol. Clin. North Am. 29, 61–84 (2015). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/25475573/Strickler, J. H. et al. Tucatinib plus trastuzumab for chemotherapy-refractory, HER2-positive, RAS wild-type unresectable or metastatic colorectal cancer (MOUNTAINEER): a multicentre, open-label, phase 2 study. Lancet Oncol. 24, 496–508 (2023). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/37142372/Kruijssen, D. E. W. van der et al. Upfront resection versus no resection of the primary tumor in patients with synchronous metastatic colorectal cancer: the randomized phase III CAIRO4 study conducted by the Dutch Colorectal Cancer Group and the Danish Colorectal Cancer Group. Ann. Oncol. 35, 769–779 (2024). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/38852675/Hitchcock, K. E., Romesser, P. B. & Miller, E. D. Local Therapies in Advanced Colorectal Cancer. Hematol. Oncol. Clin. North Am. 36, 553–567 (2022). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/35562258/Hitchcock, K. E. et al. Alliance for clinical trials in Oncology (Alliance) trial A022101/NRG-GI009: a pragmatic randomized phase III trial evaluating total ablative therapy for patients with limited metastatic colorectal cancer: evaluating radiation, ablation, and surgery (ERASur). BMC Cancer 24, 201 (2024). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/38350888/Adam, R. et al. Liver transplantation plus chemotherapy versus chemotherapy alone in patients with permanently unresectable colorectal liver metastases (TransMet): results from a multicentre, open-label, prospective, randomised controlled trial. The Lancet 404, 1107–1118 (2024). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/39306468/Elez, E. et al. Encorafenib, Cetuximab, and mFOLFOX6 in BRAF-Mutated Colorectal Cancer. N. Engl. J. Med. 392, 2425–2437 (2025). PubMed Link: https://pubmed.ncbi.nlm.nih.gov/40444708/***Fellowship Application Link: https://forms.gle/QSUrR2GWHDZ1MmWC6Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more. If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listenBehind the Knife Premium:General Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-reviewTrauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlasDominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkshipDominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotationVascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-audio-reviewColorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-audio-reviewSurgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-audio-reviewCardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-audio-reviewDownload our App:Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US
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