POPULARITY
Drs. Marianeli Rodriguez, Katherine Talcott, and Akshay Thomas join for a traditional journal club discussion covering four recent publications in major ophthalmology journals:Retinal Detachment Trends During COVID-19 (https://www.ophthalmologyretina.org/article/S2468-6530(22)00046-X/fulltext)Racial Disparities in DME Trials (https://www.ophthalmologyretina.org/article/S2468-6530(22)00040-9/fulltext)Department Gender Diversity Influence on Residency Makeup (https://www.ajo.com/article/S0002-9394(22)00043-5/fulltext)Ghost and Honorary Authorship (https://www.ajo.com/article/S0002-9394(22)00067-8/fulltext)Financial Disclosures: Dr. Rodriguez has no relevant disclosures. Dr. Sridhar is a consultant for Alcon, Allergan, Dorc, Genentech, and Regeneron. Dr. Talcott is a consultant for Genentech, Regenxbio, and Zeiss. Dr. Thomas is a consultant for Allergan, Avesis, Bausch and Lomb, and Novartis.
Episode 331: Journal Club Including Discussion of Vitreoretinal Procedure Reimbursement, Outcomes of Retinal Detachments with Multiple Surgeries, Post-Hoc Analysis of LEAVO study for retinal vein occlusion, PALADIN study for intravitreal fluocinolone implant,Drs. Shriji Patel and Katherine Talcott join to discuss four recent publications in major ophthalmology journals:Reimbursement of Vitreoretinal Procedures (https://www.ophthalmologyretina.org/article/S2468-6530(21)00379-1/fulltext)Outcomes of Eyes Undergoing Multiple Retinal Detachment Repair (https://www.ophthalmologyretina.org/article/S2468-6530(22)00019-7/fulltext)Visual Outcomes in the LEAVO Study (https://jamanetwork.com/journals/jamaophthalmology/article-abstract/2787670)PALADIN study for fluocinolone implant for diabetic macular edema (https://www.aaojournal.org/article/S0161-6420(22)00067-7/fulltext)Financial Disclosures: Dr. Sridhar is a consultant for Alcon, Allergan, Dorc, Genentech, and Regeneron. Dr. Talcott is a consultant for Genentech and has received grant funding from Regenxbio and Zeiss. Dr. Patel has no disclosures. You can now claim CME credits via the AAO website. Visit https://www.aao.org/browse-multimedia?filter=Audi
Wer heute ein bisschen was auf sich hält (oder gecheckt hat, dass der Klimawandel real ist), versucht den ökologischen Fußabdruck immer mehr zu verkleinern. Und ja, auch beim Thema Menstruation ist es durchaus angebracht mal darüber nachzudenken, wie viel Müll man mit Tampons, Binden und Slipeinlagen so produziert. Viele vermeintliche Klimaretter*innen greifen deshalb seit ein paar Jahren auf Menstruationstassen zurück, um das Blut aufzufangen. Doch ist das WIRKLICH nachhaltig? Wir haben mit Katharina von den SWR Ökocheckern drüber gesprochen. Quellen: https://www.ipoint-systems.com/blog/sind-menstruationstassen-eine-gruene-luege/ https://www.deutsche-apotheker-zeitung.de/news/artikel/2019/10/07-10-2019/menstruationstasse-statt-tampon-sinnvoll-und-sicher/chapter:3 https://www.deutsche-apotheker-zeitung.de/news/artikel/2019/10/09-10-2019/menstruationstasse-statt-tampon-sinnvoll-und-sicher/chapter:2 https://www.thelancet.com/action/showPdf?pii=S2468-2667%2819%2930111-2 https://www.rbb-online.de/rbbpraxis/rbb_praxis_service/gesundes-wissen/menstruationstasse-tampon-alternative-nachhaltig-cup-regel-blutung-hygiene.html https://www.oekotest.de/kosmetik-wellness/Menstruationstassen-im-Test-Sind-sie-besser-als-Tampons_11183_1.html https://www.swrfernsehen.de/marktcheck/oekochecker/trend-menstruationstasse-so-nachhaltig-ist-die-tampon-revolution-100.html
Open globe injury characteristics (https://jamanetwork.com/journals/jamaophthalmology/fullarticle/2759430?resultClick=1) Retinal detachments in self-injurious patients (https://www.ophthalmologyretina.org/article/S2468-6530(20)30463-2/fulltext) Eye injuries from rubber bullets used during 2020 protests (https://jamanetwork.com/journals/jamaophthalmology/article-abstract/2773503?resultClick=3)
Contributor: Don Stader, MD Educational Pearls: Majority of patients experience side effects while taking opioids Most common include nausea/vomiting, puriitis, constipation; more severe and less common include respiratory depression, addiction and overdose Opiates can cause nausea, but ondansetron (Zofran) is the wrong treatment because it’s not antidopaminergic. Instead consider using metoclopramide (Reglan), olanzapine (Zyprexa), or haloperidol (Haldol) Itching from opiates isn’t histamine mediated so hydroxyzine (Atarax) and diphenhydramine (Benadryl) aren’t effective - oddly ondansetron may help with itching. Constipation is best treated with promotility agents like Senna, rather than stool softeners References Rogers E, Mehta S, Shengelia R, Reid MC. Four Strategies for Managing Opioid-Induced Side Effects in Older Adults. Clin Geriatr. 2013 Apr;21(4): PMID: 25949094; PMCID: PMC4418642. Farmer AD, Holt CB, Downes TJ, Ruggeri E, Del Vecchio S, De Giorgio R. Pathophysiology, diagnosis, and management of opioid-induced constipation. Lancet Gastroenterol Hepatol. 2018 Mar;3(3):203-212. doi: 10.1016/S2468-1253(18)30008-6. PMID: 29870734. Summarized by Jackson Roos, MS4 | Edited by Erik Verzemnieks, MD The Emergency Medical Minute is excited to announce that we are now offering AMA PRA Category 1 credits™ via online course modules. To access these and for more information, visit our website at www.emergencymedicalminute.com/cme-courses/ and create an account.
Estudo revela que pessoas que comem pouco carboidrato morrem mais cedo! Arigo citado:Seidelmann SB, Claggett B, Cheng S, Henglin M, Shah A, Steffen LM, Folsom AR, Rimm EB, Willett WC, Solomon SD. Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis. Lancet Public Health. http://dx.doi.org/10.1016/S2468-2667(18)30135-X
The Filtrate:Joel TopfSwapnil HiremathSamira FaroukJennie LinMatt SparksAnd special guests:Agnes Fozo: John L. Shapiro Chair of Pathology at Vanderbilt University and on Twitter: https://twitter.com/AgnesFogoHua Su: Professor of Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaOsama El Shamy: Home Therapy Fellow at Mount Sinai and on Twitter: https://twitter.com/osamaelshamy88Chirag Parikh: Director of Nephrology Johns Hopkins and on Twitter: https://twitter.com/KidneydrChiragShow Notes:Mark Denison, Corona virus expert. https://www.vumc.org/viiii/person/mark-r-denison-md and on Twitter: https://twitter.com/DenisonLabDiscussion on Twitter that the 3electron microgrpahs may show clathrin coated pits rather than Conorna virus. https://twitter.com/vighnesh_w/status/1250880961463513088?s=20Chris Larsen’s case of collapsing glomerulopathy in a patient with COVID-19 https://www.kireports.org/article/S2468-0249(20)31172-4/abstractOsler's rule: States that a neurological defect has to be related to a specific lesion, in contrast to Hickam's dictum, which states that the neurological defect can be due to several lesions.Altered Lipid Metabolism in Recovered SARS Patients Twelve Years after Infection. https://www.ncbi.nlm.nih.gov/pubmed/28831119We don’t record (or roll) on the sabath https://www.youtube.com/watch?v=GPo9OBrIOi4Using a dialysis machine to make CRRT dialysate, the Tweet: https://twitter.com/KidneydrChirag/status/1249867795602583554Derek Fine, Parikh’s partner in crime: https://www.hopkinsmedicine.org/profiles/results/directory/profile/0007605/derek-fine and on Twitter: https://twitter.com/DerekFineMDTablo Machine makes its own dialysate. It does not look like a cooler. https://www.outsetmedical.com/tablo/Is Canada a communist country? https://www.quora.com/Is-Canada-a-communist-countryLokelma is not a sponsor of Freely FilteredComplications and Catheter Survival With Prolonged Embedding of Peritoneal Dialysis Catheters https://pubmed.ncbi.nlm.nih.gov/18281722/Ontario Nursing Homes,”It felt like a war zone” https://www.pri.org/stories/2020-04-24/it-felt-war-zone-coronavirus-tears-through-canada-nursing-homes
In a special episode of Bowel Sounds, hosts Dr. Jenn Lee, Dr. Peter Lu, and Dr. Jason Silverman talk about COVID-19 and how this pandemic is impacting the world of pediatric gastroenterology. We review the latest research on how COVID-19 impacts our patients -- specifically how it impacts children and the digestive tract. We also discuss the latest guidance from our GI societies, including on precautions to take regarding endoscopy. As always, the discussion, views, and recommendations in this podcast are the sole responsibility of the hosts and are subject to change over time with advances in the field.Produced by: Peter LuResources:Visit NASPGHAN's COVID-19 website here.Visit the CDC COVID-19 website here.See WHO daily situation reports here.See the Johns Hopkins COVID-19 tracker here.An alternative tracker at Bing is here.References:Dong Y, et al. Epidemiological Characteristics of 2143 Pediatric Patients With 2019 Coronavirus Disease in China. Pediatrics. 2020 Mar 16. pii: e20200702. doi: 10.1542/peds.2020-0702.Cai J, et al. A Case Series of children with 2019 novel coronavirus infection: clinical and epidemiological features. Clin Infect Dis. 2020 Feb 28. pii: ciaa198. doi: 10.1093/cid/ciaa198.Xiao F, et al. Evidence for gastrointestinal infection of SARS-CoV-2. Gastroenterology. 2020 Mar 3. pii: S0016-5085(20)30282-1. doi: 10.1053/j.gastro.2020.02.055.Pan L, et al. Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: a descriptive, cross-sectional, multicenter study. Am J Gastroenterol. 2020 Mar.Zhang C, et al. Liver injury in COVID-19: management and challenges. Lancet Gastroenterol Hepatol. 2020 Mar 4. pii: S2468-1253(20)30057-1. doi: 10.1016/S2468-1253(20)30057-1.Repici A, et al. Coronavirus (COVID-19) outbreak: what the department of endoscopy should know. Gastrointest Endosc. 2020 Mar 13. pii: S0016-5107(20)30245-5. doi: 10.1016/j.gie.2020.03.019.Support the show (https://www.naspghan.org/content/87/en/foundation/donate)
Background: The rising number of young people going to university has led to concerns about an increasing demand for student mental health services. We aimed to assess whether provision of mindfulness courses to university students would improve their resilience to stress. Methods: We did this pragmatic randomised controlled trial at the University of Cambridge, UK. Students aged 18 years or older with no severe mental illness or crisis (self-assessed) were randomly assigned (1:1), via remote survey software using computer-generated random numbers, to receive either an 8 week mindfulness course adapted for university students (Mindfulness Skills for Students [MSS]) plus mental health support as usual, or mental health support as usual alone. Participants and the study management team were aware of group allocation, but allocation was concealed from the researchers, outcome assessors, and study statistician. The primary outcome was self-reported psychological distress during the examination period, as measured with the Clinical Outcomes in Routine Evaluation Outcome Measure (CORE–OM), with higher scores indicating more distress. The primary analysis was by intention to treat. This trial is registered with the Australia and New Zealand Clinical Trials Registry, number ACTRN12615001160527. Findings: Between Sept 28, 2015, and Jan 15, 2016, we randomly assigned 616 students to the MSS group (n=309) or the support as usual group (n=307). 453 (74%) participants completed the CORE–OM during the examination period and 182 (59%) MSS participants completed at least half of the course. MSS reduced distress scores during the examination period compared with support as usual, with mean CORE–OM scores of 0·87 (SD 0·50) in 237 MSS participants versus 1·11 (0·57) in 216 support as usual participants (adjusted mean difference −0·14, 95% CI −0·22 to −0·06; p=0·001), showing a moderate effect size (β −0·44, 95% CI −0·60 to −0·29; p
For this very special 2019 World Hepatitis Day episode, Annie and Carla talk with Australian researchers Dr Tanya Applegate from The Kirby Institute and Professor Margaret Hellard AM from The Burnet Institute about the ‘awesomely massive’ “Accelerating the elimination of viral hepatitis: a Lancet Gastroenterology & Hepatology Commission” and discuss the power of collaboration in the global fight against viral hepatitis. Links Accelerating the elimination of viral hepatitis: a Lancet Gastroenterology & Hepatology Commission https://doi.org/10.1016/S2468-1253(18)30270-X
In this second episode from the Harm Reduction International Conference 2019, Carla and Annie catch up with Carol Strike and Gillian Kolla -- legends from the frontlines of the overdose crisis in Toronto, Canada, about police and their attitudes to safe injecting facilities, setting up an unsanctioned safe injecting site in a public park in Toronto and issues in doing research with highly criminalised communities. Links Creating and sustaining cooperative relationships between supervised injection services and police: A qualitative interview study of international stakeholders https://doi.org/10.1016/j.drugpo.2018.08.001 A scoping review of harm reduction training for police officers https://doi.org/10.1111/dar.12904 Canada's overdose crisis: authorities are not acting fast enough https://doi.org/10.1016/S2468-2667(19)30040-4 Toronto Overdose Prevention Service https://twitter.com/TorontoOPS For more info on SpeakEasy: https://csrh.arts.unsw.edu.au/research/podcast-speakeasy-with-annie-madden-and-carla-treloar/
Brought to you by CSMi Does the weight of an athlete matter when considering how much force they can handle? Is obesity the cause of disease or just something else that was caused by the cause of disease; whatever that actually is? Here we take a look at understanding predictors versus understanding causation and how this affects interventions for public health. Why causality, and not prediction, should guide obesity prevention policy. Chiolero A. Lancet Public Health. 2018 Oct;3(10):e461-e462. doi: 10.1016/S2468-2667(18)30158-0. Epub 2018 Sep 1. The article mentioned in the Mail Hole: Normalization influences knee abduction moment results: Could it influence ACL-injury research, too? Norcross MF, Johnson ST, Pollard CD, Chang EW, Hoffman MA. J Sci Med Sport. 2017 Apr;20(4):318-321. doi: 10.1016/j.jsams.2016.10.005. Epub 2016 Oct 21. Due to copyright laws, unless the article is open source we cannot legally post the PDF on the website for the world to download at will. That said, if you are having difficulty obtaining an article, contact us. Produced by: Matt Hunter Music for PT Inquest: "The Science of Selling Yourself Short" by Less Than Jake Used by Permission
Here we discuss the top 10 easy to start ideas to get you going on your weight-loss journey. Follow up: after publication a study came out in Lancet that shows high animal protein diets (like keto) are associated with increased mortality. You can visit here for more information. https://www.thelancet.com/action/showPdf?pii=S2468-2667%2818%2930135-X