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Send us Fan MailThis week on The Incubator Podcast, Ben and Daphna dig into four studies reshaping bedside decisions. They open questioning whether routine DAT screening for ABO and RhD incompatibility still earns its place, finding transcutaneous bilirubin alone predicts phototherapy need just as well. Next, a Swedish national registry of over two million births links missed intramuscular vitamin K, and rising oral substitution, to a near-doubling of bleeding and intracranial hemorrhage risk. Ben then presents the PHILODENDRON pilot trial out of Milan, testing initial delivery-room CPAP of 5 versus 8 cmH2O in infants under 30 weeks, feasible and safe, but not yet enough to settle the physiology question. Daphna closes Journal Club with a SART-linked study tying IVF conception to significantly higher odds of VACTERL association. The week wraps with Ben and Eli on Neo News, unpacking a study showing birth certificates miss nearly 40% of true NICU admissions, with troubling racial disparities.----Utility of DAT in Low-Risk Neonates With ABO or RhD Incompatibility. Tsai TL, Ma T, Nester T.Pediatrics. 2026 Sep 1;158(3):e2026076989. doi: 10.1542/peds.2026-076989.PMID: 42642037Vitamin K Prophylaxis in Newborns and Bleeding in Infancy. Simatou E, Tsamantioti E, Hallström A, Stephansson O, Razaz N, Persson M, Bolk J.JAMA Pediatr. 2026 Sep 1;180(9):995-1004. doi: 10.1001/jamapediatrics.2026.2606.PMID: 42440325Initial CPAP of 5 versus 8 cmH2O during delivery room stabilisation of very preterm infants: the PHILODENDROOM pilot randomised trial. Cavigioli F, Bresesti I, Castoldi F, Gatto S, Lupo E, Rossi S, La Verde A, Bianchi S, Meneghin F, Viaroli F, Pivetti V, Manfredini V, Cannata G, Bastrenta P, Fontana P, Stucchi I, Daniele I, Chiera M, Lista G.Eur J Pediatr. 2026 Aug 17;185(9):673. doi: 10.1007/s00431-026-07322-6.PMID: 42608615 Free PMC article. Clinical Trial.In Vitro Fertilization and VACTERL Birth Defects. Tark JY, Richard MA, Schraw JM, Fisher SC, Betancourt D, Stone SL, Forestieri NE, Baker VL, Cameron K, Eisenberg ML, Belva F, Lu Y, Williams CL, Sutcliffe AG, Lupo PJ, Luke B.JAMA Netw Open. 2026 Aug 3;9(8):e2629355. doi: 10.1001/jamanetworkopen.2026.29355.PMID: 42616500 Free PMC article.Birth certificate data substantially misrepresent actual NICU admissions, including among most vulnerable. Hughes CS, Lorch SA, Schmitt S, Passarella M, Phibbs CS.J Perinatol. 2026 Jul;46(7):1307-1312. doi: 10.1038/s41372-026-02726-6. Epub 2026 May 27.PMID: 42204354Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!
Send us Fan MailBen and Eli dig into a Journal of Perinatology study that asks a deceptively simple question: can we trust birth certificate data to tell us how many babies actually need NICU care? The answer, it turns out, is no. Nearly 40% of NICU admissions are missing from birth certificates, with the biggest gaps among full-term and late-preterm infants, and troubling racial disparities in which admissions get missed. Ben and Eli unpack what this means for how states and hospitals allocate resources, why underreporting could be quietly starving NICUs of funding and attention, and why pairing solid epidemiologic data with individual bedside stories may be the most effective way to make the case for better-resourced newborn care.----Birth certificate data substantially misrepresent actual NICU admissions, including among most vulnerable. Hughes CS, Lorch SA, Schmitt S, Passarella M, Phibbs CS.J Perinatol. 2026 Jul;46(7):1307-1312. doi: 10.1038/s41372-026-02726-6. Epub 2026 May 27.PMID: 42204354Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!
The Podcasts of the Royal New Zealand College of Urgent Care
There are a number of ways you can "crack" a joint. Some are relevant to urgent care, and some are just interesting. Check out the paper mentioned Unger DL. Does knuckle cracking lead to arthritis of the fingers? Arthritis Rheum. 1998 May;41(5):949-50. doi: 10.1002/1529-0131(199805)41:53.0.CO;2-3. PMID: 9588755. https://pubmed.ncbi.nlm.nih.gov/9588755/ Rizvi A, Loukas M, Oskouian RJ, Tubbs RS. Let's get a hand on this: Review of the clinical anatomy of "knuckle cracking". Clin Anat. 2018 Sep;31(6):942-945. doi: 10.1002/ca.23243. Epub 2018 Oct 18. PMID: 30080300. https://pubmed.ncbi.nlm.nih.gov/30080300/ Deweber K, Olszewski M, Ortolano R. Knuckle cracking and hand osteoarthritis. J Am Board Fam Med. 2011 Mar-Apr;24(2):169-74. doi: 10.3122/jabfm.2011.02.100156. PMID: 21383216. https://pubmed.ncbi.nlm.nih.gov/21383216/ www.rnzcuc.org.nz podcast@rnzcuc.org.nz https://www.facebook.com/rnzcuc https://twitter.com/rnzcuc Music licensed from www.premiumbeat.com Full Grip by Score Squad This podcast is intended to assist in ongoing medical education and peer discussion for qualified health professionals. Please ensure you work within your scope of practice at all times. For personal medical advice, always consult your usual doctor
If you've been following health and medical headlines over the past few weeks, you've likely seen a renewed and urgent conversation around postpartum depression—a condition that affects millions of new mothers worldwide, often with devastating consequences. While we've long understood that postpartum depression is deeply multifactorial—shaped by a complex web of hormonal shifts, psychological stressors, and socio-economic factors—a compelling wave of new data points to a key physical variable that might be playing a far bigger role than we previously realized: how we manage pain during cesarean deliveries. Specifically, emerging studies are highlighting a striking potential association between the use of general anesthesia during C-sections and a higher risk of subsequent postpartum depression compared to neuraxial options like epidurals or spinal blocks. Why would the choice of anesthetic in the operating room ripple into neurochemical changes weeks or months later? In today's episode, we're going to dive deep into this latest data. We'll break down what the numbers actually tell us, examine the clinical nuances, and explore the potential biological and neuroendocrine mechanisms of action—from acute inflammatory cascades to neurotransmitter disruption—that could explain this link.1. Oh TK, Song IA. Neuraxial versus General Anesthesia for Cesarean Delivery and the Risk of Postpartum Depression: A Nationwide Population-Based Study. Anaesth Crit Care Pain Med. 2026 Jun 3:101871. doi: 10.1016/j.accpm.2026.101871. Epub ahead of print. PMID: 42242358.2. Fagan JJ, Dufour SI, Duet SJ, Downs EM, Siddaiah H, Viswanath O, Shekoohi S, Kaye AD. Influence of Neuraxial Anesthesia Technique During Vaginal and Cesarean Delivery and Association with Postpartum Depression: A Narrative Review of Literature. Neuropsychiatr Dis Treat. 2026 Apr 14;22:579920.3. Guglielminotti J, Monk C, Russell MT, Li G. Association of General Anesthesia for Cesarean Delivery with Postpartum Depression and Suicidality. Anesth Analg. 2025 Sep 1;141(3):618-628. 4. Xie SC, Liu CH, Hung YT. Association between postpartum depression and anaesthesia methods in women undergoing caesarean section: A systematic review and meta-analysis. Eur J Anaesthesiol. 2026 Jan 1;43(1):66-73. doi: 10.1097/EJA.0000000000002252. Epub 2025 Aug 6. PMID: 40771157.
Chuck and Chris briefly review challenges with the US healthcare system but spend most of the episode discussing difficult hand fracture cases.Meyer ZI, Goldfarb CA, Calfee RP, Wall LB. The Central Slip Fracture: Results of Operative Treatment of Volar Fracture Subluxations/Dislocations of the Proximal Interphalangeal Joint. J Hand Surg Am. 2017 Jul;42(7):572.e1-572.e6. doi: 10.1016/j.jhsa.2017.03.030. Epub 2017 May 3. PMID: 28476538; PMCID: PMC5510930.See www.practicelink.com/theupperhand for more information from our partner on job search and career opportunities.The Upper Hand Podcast is sponsored by Checkpoint Surgical, a provider of innovative solutions for peripheral serve surgery. To learn more, visit https://checkpointsurgical.com/.As always, thanks to @iampetermartin for the amazing introduction and concluding music.For additional links, the catalog. Please see https://www.ortho.wustl.edu/content/Podcast-Listings/8280/The-Upper-Hand-Podcast.aspx
The Podcasts of the Royal New Zealand College of Urgent Care
In this first episode of Busting Myths with Laura and Dinesh, Dr Laura Hamill and Dr Dinesh Deonarain consider whether spider bites always require antibiotics and the evidence around the need to split plaster casts. Check out the papers Laura and Dinesh recommend you read. Isbister GK, Gray MR. White-tail spider bite: a prospective study of 130 definite bites by Lampona species. Med J Aust. 2003 Aug 18;179(4):199-202. doi: 10.5694/j.1326-5377.2003.tb05499.x. PMID: 12914510. Link to paper Zaino CJ, Patel MR, Arief MS, Pivec R. The effectiveness of bivalving, cast spreading, and webril cutting to reduce cast pressure in a fiberglass short arm cast. J Bone Joint Surg Am. 2015 Mar 4;97(5):374-80. doi: 10.2106/JBJS.N.00579. PMID: 25740027. Abstract Barvelink B, Reijman M, Smidt S, Miranda Afonso P, Verhaar JAN, Colaris JW; CAST study group; CAST study group; van Beek F, Bouwhuis MG, Bruijninckx MMM, Greeven APA, Gosens T, Kok MJ, Kokke MC, Kraan GA, van Lakwijk K, Leijnen M, van Loon M, van Rijssel DA, Schep NWL, Scholtens L, Wijffels MME, Slebioda N, van der Zwaal P, Zwets E. Redisplacement of reduced distal radius fractures in adults: does the type of casting play a role? The CAST study, a multicentre cluster randomized controlled trial. Bone Joint J. 2024 Jul 1;106-B(7):696-704. doi: 10.1302/0301-620X.106B7.BJJ-2024-0014.R1. Erratum in: Bone Joint J. 2024 Sep 1;106-B(9):1032. doi: 10.1302/0301-620X.106B9.BJJ-2024-00050. PMID: 38945541. Abstract Wik TS, Aurstad AT, Finsen V. Colles' fracture: dorsal splint or complete cast during the first 10 days? Injury. 2009 Apr;40(4):400-4. doi: 10.1016/j.injury.2008.08.044. Epub 2009 Feb 4. PMID: 19195651. Abstract Bullen M, Kinealy J, Blanchard R, Rodda C, Pivonka P. Comparison of the moulding ability of Plaster of Paris and polyester cast material in the healthy adult forearm. Injury. 2017 Nov;48(11):2586-2589. doi: 10.1016/j.injury.2017.08.010. Epub 2017 Aug 16. PMID: 28870625. Abstract If you have any comments or suggestions of myths for their future consideration, email podcast@rnzcuc.org.nz Always follow your local guidelines and policies. These discussions are designed to encourage you to engage with the literature. www.rnzcuc.org.nz podcast@rnzcuc.org.nz https://www.facebook.com/rnzcuc https://twitter.com/rnzcuc Music by Karl Casey @White Bat Audio. Second Life from the Album White Bat 48 - available at Bandcamp This podcast is intended to assist in ongoing medical education and peer discussion for qualified health professionals. Please ensure you work within your scope of practice at all times. For personal medical advice, always consult your usual doctor
In this Complex Care Journal Club podcast episode, Dr. Jason Zamkoff discusses a quality-improvement cohort study of a surgical hospitalist co-management program (Surgical Hospitalist Assisted Recovery/SHARe Team, or “Pink Team”) for children with medical complexity at Children's Hospital Colorado. They describe how patients are selected using an internal complexity score and the institutional trust-building needed to launch the program, resulting in fewer post-operative emergency transfers to intensive care. Next steps include developing an externally validated complexity scoring tool and extending hospitalist involvement into the pre-operative period. SPEAKER Jason Zamkoff, MD Professor of Pediatrics University of Colorado School of Medicine Pediatric Hospitalist Children's Hospital Colorado HOST Kilby Mann, MD Associate Professor, Director of Pediatric Rehabilitation University of North Carolina School of Medicine DATE Initial publication date: September 8, 2026. JOURNAL CLUB ARTICLE Zamkoff J, Acker SN, Martin A, Anderson L, Bennett H, Thysens J, Thomas JJ, Conant M, Kurtz M, Gupta R, Scarberry J, Burke M, Koehler R, Rolison E, Whitney G, Ziniel SI, Carney KP, Wilcox D, Lockwood JM. Surgical Hospitalist Assisted REcovery (SHARe): Preventing Post-Operative Emergency Transfers. Hosp Pediatr. 2026 Jul 21:e2025008778. doi: 10.1542/hpeds.2025-008778. Epub ahead of print. PMID: 42476571. OTHER ARTICLES REFERENCED Martin A, Acker S, Hankinson TC, Zamkoff J. Perspectives on Interdisciplinary Perioperative Care for Children with Medical Complexity. Pediatr Clin North Am. 2026 Apr;73(2):513-524. doi: 10.1016/j.pcl.2025.12.003. Epub 2026 Feb 26. PMID: 42020046. TRANSCRIPT https://cdn.bfldr.com/D6LGWP8S/as/9c5mmqqq86knpmsgss5xrm8/Zamkoff_transcript_9-1-26 Clinicians across healthcare professions, advocates, researchers, and patients/families are all encouraged to engage and provide feedback! You can recommend an article for discussion using this form: https://forms.gle/Bdxb86Sw5qq1uFhW6. Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Zamkoff J, Mann K. The Pink Team Effect: Reducing Postoperative Emergency Transfers in Complex Care. 08/2026. OPENPediatrics. Online Podcast. https://soundcloud.com/openpediatrics/the-pink-team-effect-reducing-postoperative-emergency-transfers-in-complex-care
MASH is often called a silent disease, but its impact can be significant. Join Dr. Gerry Clancy and University of Iowa liver specialists Dr. Marta Tejedor Bravo and Dr. Alan Gunderson as they explore risk factors, screening, disease progression, and emerging therapies that are reshaping care for patients with metabolic liver disease. Liver Wellness | The University of Iowa Iowa Liver Wellness Symposium: Cirrhosis Care in Motion 2026 5k Race - Run for Your Liver, Run for Your life (and last year's video Run for Your Liver, Run for Your Life) Episode Transcript CE Credit Available Host: Gerard Clancy, MD Senior Associate Dean for External Affairs Professor of Psychiatry and Emergency Medicine University of Iowa Carver College of Medicine Guests: Alan E. Gunderson, MD Clinical Associate Professor of Internal Medicine-Gastroenterology and Hepatology University of Iowa Carver College of Medicine Marta Tejedor Bravo, MD, MSc, PhD Clinical Associate Professor of Internal Medicine-Gastroenterology and Hepatology University of Iowa Carver College of Medicine Financial Disclosures: Dr. Clancy, Dr. Tejedor Bravo, and the members of the Rounding@IOWA planning committee have disclosed no relevant financial relationships. Dr. Gunderson has disclosed the following relationships: CymaBay Therapeutics, Inc.; GigaGen, Inc.; LISCure Biosciences, Inc. - Sponsored Research Relevant financial relationships have been mitigated. Nurse: The University of Iowa Roy J. and Lucille A. Carver College of Medicine designates this activity for a maximum of 1.00 ANCC contact hour. Pharmacist and Pharmacy Tech: The University of Iowa Roy J. and Lucille A. Carver College of Medicine designates this knowledge-based activity for a maximum of 1.00 ACPE contact hours. Credit will be uploaded to the NABP CPE Monitor within 60 days after the activity completion. Pharmacists must provide their NABP ID and DOB (MMDD) to receive credit. JA0000310-0000-26-058-H01 Physician: The University of Iowa Roy J. and Lucille A. Carver College of Medicine designates this enduring material for a maximum of 1.00 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Other Health Care Providers: A certificate of completion will be available after successful completion of the course. (It is the responsibility of licensees to determine if this continuing education activity meets the requirements of their professional licensure board.) References: Rinella ME, Neuschwander-Tetri BA, Siddiqui MS, Abdelmalek MF, Caldwell S, Barb D, Kleiner DE, Loomba R. AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease. Hepatology. 2023 May 1;77(5):1797-1835. doi: 10.1097/HEP.0000000000000323. Epub 2023 Mar 17. PMID: 36727674; PMCID: PMC10735173. European Association for the Study of the Liver (EASL); European Association for the Study of Diabetes (EASD); European Association for the Study of Obesity (EASO). EASL-EASD-EASO Clinical Practice Guidelines on the management of metabolic dysfunction-associated steatotic liver disease (MASLD). J Hepatol. 2024 Sep;81(3):492-542. doi: 10.1016/j.jhep.2024.04.031. Epub 2024 Jun 7. PMID: 38851997. Younossi ZM, Zelber-Sagi S, Lazarus JV, Wong VW, Yilmaz Y, Duseja A, Eguchi Y, Castera L, Pessoa MG, Oliveira CP, El-Kassas M, Tsochatzis E, Fan JG, Spearman CW, Tacke F, Castellanos Fernandez MI, Alkhouri N, Schattenberg JM, Romero-Gómez M, Noureddin M, Allen AM, Ong JP, Roberts SK, Shubrook JH, Burra P, Kohli R, Kautz A, Holleboom AG, Lam B, Isaacs S, Macedo P, Gastaldelli A, Henry L, Ivancovsky-Wajcman D, Nader F, de Avila L, Price JK, Mark HE, Villota-Rivas M, Barberá A, Kalligeros M, Gerber LH, Alqahtani SA. Global Consensus Recommendations for Metabolic Dysfunction-Associated Steatotic Liver Disease and Steatohepatitis. Gastroenterology. 2025 Oct;169(5):1017-1032.e2. doi: 10.1053/j.gastro.2025.02.044. Epub 2025 Apr 11. PMID: 40222485. Mladenić K, Lenartić M, Marinović S, Polić B, Wensveen FM. The "Domino effect" in MASLD: The inflammatory cascade of steatohepatitis. Eur J Immunol. 2024 Apr;54(4):e2149641. doi: 10.1002/eji.202149641. Epub 2024 Feb 5. PMID: 38314819. Harrison SA, Bedossa P, Guy CD, Schattenberg JM, Loomba R, Taub R, Labriola D, Moussa SE, Neff GW, Rinella ME, Anstee QM, Abdelmalek MF, Younossi Z, Baum SJ, Francque S, Charlton MR, Newsome PN, Lanthier N, Schiefke I, Mangia A, Pericàs JM, Patil R, Sanyal AJ, Noureddin M, Bansal MB, Alkhouri N, Castera L, Rudraraju M, Ratziu V; MAESTRO-NASH Investigators. A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis. N Engl J Med. 2024 Feb 8;390(6):497-509. doi: 10.1056/NEJMoa2309000. PMID: 38324483. Sanyal AJ, Newsome PN, Kliers I, Østergaard LH, Long MT, Kjær MS, Cali AMG, Bugianesi E, Rinella ME, Roden M, Ratziu V; ESSENCE Study Group. Phase 3 Trial of Semaglutide in Metabolic Dysfunction-Associated Steatohepatitis. N Engl J Med. 2025 Jun 5;392(21):2089-2099. doi: 10.1056/NEJMoa2413258. Epub 2025 Apr 30. PMID: 40305708.
En este episodio les traemos una reseña de la novela The Night Swim, de la autora Megan Goldin, su primera novela, en la que combina elementos de crimen, misterio y asuntos legales.La historia nos presenta a Rachel Krall, una popular creadora de contenido de true crime que ha alcanzado gran éxito gracias a su podcast. Sin embargo, su trabajo también ha generado controversia. En el pasado, uno de sus episodios provocó un gran revuelo y contribuyó, de alguna manera, a que un hombre inocente terminara encarcelado injustamente.Ahora, durante la tercera temporada de su podcast, Rachel decide seguir de cerca un nuevo caso en Carolina del Norte: un joven y prometedor nadador es acusado de violación, y Rachel viaja hasta el lugar junto con su equipo para cubrir el juicio.Pero, antes de llegar, recibe una carta anónima que cambia por completo el rumbo de su investigación. Alguien le pide ayuda para esclarecer un crimen ocurrido muchos años atrás, un caso que aparentemente ha quedado en el pasado, pero que podría estar relacionado con lo que está sucediendo en el presente.A partir de aquí comienza una historia que mezcla investigación periodística, secretos del pasado y un caso judicial que podría tener mucho más detrás de lo que parece.Si estas interesado en esta novela dale click al siguiente enlace.
Twin Flames, Myth or Higher Consciousness Mystery of Divine making. Join me on this Sunday morning Higher Consciousness walk as we explore deeper.THANKS FOR Being here
Today we are diving into a topic that is incredibly close to my heart—one that has the potential to fundamentally change how we approach prenatal care and protect pregnant patients. We're talking about low-dose aspirin for the prevention of hypertensive disorders of pregnancy. Now, if you follow current formal guidelines, you probably know the standard protocol: 81 milligrams a day, prescribed based on specific risk factors. But there's a growing body of evidence suggesting we might be underdosing—and under-prescribing. What if 162 milligrams taken universally across the board is actually far more effective?In today's episode, we're unpacking a brand-new, groundbreaking study published in the American Journal of Obstetrics & Gynecology. And I'm especially excited to cover this one because it comes straight out of my alma mater, Parkland Hospital! This study takes a bold look at real-world outcomes by comparing a period of universal 162-milligram aspirin use directly against a historical period when aspirin wasn't recommended at all. Did a higher, universal dose significantly cut down on hypertensive disorders? And just as importantly …were there any adverse safety events we need to be aware of? Grab your coffee, settle in, and let's get into the details.1. Duryea E, Ambia A, Pruszynski J. et al. Universal Aspirin Dispensation for Prevention of Preeclampsia in a High-Risk Population. AJOG, 2026; ePub 8/27/282. Hypertension in pregnancy. Report of the American College of Obstetricians and Gynecologists' Task Force on Hypertension in Pregnancy. Obstet Gynecol. 2013 Nov;122(5):1122-1131. 3. ACOG Issues Updated Hypertension Guidance, Discusses New ACC/AHA Criteria (2018): https://www.acog.org/news/news-releases/2018/12/acog-issues-updated-hypertension-guidance4. Low-Dose Aspirin Use During Pregnancy, ACOG Committee Opinion Number 743 (2018)5. Low-Dose Aspirin Use for the Prevention of Preeclampsia and Related Morbidity and Mortality. ACOG Practice Advisory; December 2021
What happens when the stress of being a first responder doesn't just stay in your head but starts showing up in your gut?Today, we're joined by Police Chief Michael Assad Jr. of the Rochester, Massachusetts Police Department for an honest conversation about the often-overlooked connection between first responder stress, gut health, IBS, and nutrition.From high-pressure calls and long shifts to those unexpected “code brown” moments, chronic stress can take a serious toll on the digestive system. We'll talk about recognizing those warning signs, why gut health deserves more attention in the first responder community, and how nutrition, stress management and everyday habits can play a role in feeling better and performing at your best.This is a conversation about stress, resilience, and taking care of the part of your body that may be trying to tell you it's time to slow down and pay attention.We share practical ways to build a culture where officers can recover from adrenaline, fuel better on shift, and get support without stigma. • why shift work and disrupted routines can trigger IBS symptoms • the “SHIT” acronym: shift work, high octane habits, irregular nutrition, tactical stress • how energy drinks, dehydration, and gas station food can backfire fast • simple leadership moves that normalize wellness and real help seeking • fitness incentives, workout on duty, and building a wellness room • on scene tools like box breathing and diaphragmatic breathing • gentle diet cleanup basics: adjusting caffeine, alcohol, hydration, and fiber, per tolerance• nicotine pouches and stress habits that can worsen gut symptoms • when to see a doctor and what red flags to watch for • why a clear diagnosis can lower stress and improve symptoms Don't forget to subscribe, rate, and leave us a comment. You can also follow us on social media @TheGutHealthPodcast, where we'd love for you to share your thoughts, questions, and experiences. This podcast was sponsored by Ardelyx.Sorry for Kate's raspy voice, she's just getting over a cold! And a big thank-you to Megan for holding down the fort. ❤️References:Hartley TA, Violanti JM, Mnatsakanova A, Andrew ME, Burchfiel CM. Military experience and levels of stress and coping in police officers. Int J Emerg Ment Health. 2013;15(4):229-39. PMID: 24707586; PMCID: PMC4734366.Shin A, Xu H, Imperiale TF. The Prevalence, Humanistic Burden, and Health Care Impact of Irritable Bowel Syndrome Among United States Veterans. Clin Gastroenterol Hepatol. 2023 Apr;21(4):1061-1069.e1. doi: 10.1016/j.cgh.2022.08.005. Epub 2022 Aug 11. PMID: 35964894; PMCID: PMC9918609.Demo of diaphragmatic breathing.Learn more about Kate and Dr. Riehl:Website: www.katescarlata.com and www.drriehl.comInstagram: @katescarlata @drriehl and @theguthealthpodcastOrder Kate and Dr. Riehl's book, Mind Your Gut: The Science-Based, Whole-body Guide to Living Well with IBS. The information included in this podcast is not a substitute for professional medical advice, examination, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider before starting any new treatment or making changes to existing treatment.
Today, we are tackling a massive grey area in obstetrics/maternal-fetal medicine: What happens after early fetal growth restriction resolves? When a baby bounces back on the growth chart during the second or third trimester, are they completely out of the woods? Or is there a hidden, lingering risk we aren't talking about enough? To find out, we're doing a deep dive into two major publications that dropped just this month, in August 2026 in sister journals (AJOG and AJOG MFM). Both are retrospective, both ask the exact same burning question…and get this: they arrive at completely opposing conclusions. How is that possible? Listen in for details. 1. Melamed B, Mei-Dan E, Aviram A. Sonographic fetal weight estimation percentiles should be interpreted with caution in the second trimester. Int J Gynaecol Obstet. 2026 May;173(2):930-939. doi: 10.1002/ijgo.70693. Epub 2025 Nov 25. PMID: 41288086.2. Ramos SZ, Has P, Gimovsky AC, Danilack VA, Savitz DA, Lewkowitz AK. Outcomes among Neonates after a Diagnosis of Persistent or Transient Fetal Growth Restriction Delivered at Term. Am J Perinatol. 2024 May;41(S 01):e1470-e1477. doi: 10.1055/a-2051-3859. Epub 2023 Mar 9. Erratum in: Am J Perinatol. 2024 May;41(S 01):e1478. doi: 10.1055/s-0044-1786526. PMID: 36894159; PMCID: PMC10562520.3. Keller N, Jackson F, Abelman S .Neonatal morbidity following resolution of fetal growth restriction diagnosed at second-trimester anatomy ultrasound. American Journal of Obstetrics & Gynecology MFM, 2026; Aug 8. 4. Cenac LA, Wodoslawsky S, Patel V, McLaren Jr. R, Aghai ZH, Makhamreh MM, Al-Kouatly HB, Persistent, Resolved, and Absent Fetal Growth Restriction: A Comparison of Neonatal Outcomes, American Journal of Obstetrics and Gynecology (2026), doi: https:// doi.org/10.1016/j.ajog.2026. Aug 19
En este episodio, Any nos sumerge en las páginas de Piel, la sangrienta y desgarradora novela del autor Fernando Gamboa. Esta historia funciona como la precuela del aclamado libro Redención, sirviendo como el punto de partida perfecto para entender la oscuridad que rodea a sus personajes.La trama arranca de forma implacable cuando la agente Nuria descubre el brutal asesinato de una persona sumamente poderosa en la ciudad. Sin embargo, este macabro hallazgo es solo la primera ficha de un dominó de crímenes feroces que comienzan a sembrar el caos en las calles. Determinada, intrépida y sin importar el peligro que aceche, Nuria iniciará una cacería incansable donde no se detendrá ante nada ni nadie hasta dar con el verdadero culpable.Te dejamos el enlace por si te interesa este libro.
What does it mean to be free? That is one of life's biggest questions, and has occupied the minds of philosophers for time immemorial. But what does it mean to be metabolically free? Hangry? Post-meal slumps? Type II diabetic? These are all examples of the opposite - metabolic imprisonment. That's why we decided to revisit this episode with Ben Azadi to rediscover what it means to be free of this "prison", some of you find yourselves in.Ben is an incredible advocate for metabolic health, someone who walks the talk with his own pain to purpose story and someone who has made a personal impact on a member of my family.In 2008, Ben Azadi was an obese man who went through a personal health transformation of releasing 80 pounds of extra weight, and getting metabolically healthy. Ever since, Ben Azadi, FDN-P, has been on a mission to help 1 billion people live a healthier lifestyle. Ben has over 15 years of experience in the health industry, and he's the author of four best-selling books, including his latest Keto Flex. Ben has been the go-to source for intermittent fasting and the ketogenic diet since 2013. He is known as ‘The Health Detective' because he investigates dysfunction, and he educates, not medicates, to bring the body back to normal function. Ben is the founder of Keto Kamp; a global brand bringing awareness to ancient healing strategies such as the keto diet and fasting. Get his new book “Metabolic Freedom: A 30-Day Guide to Restore Your Metabolism, Heal Hormones & Burn Fat” NOW, https://tinyurl.com/metabolic-freedomJoin us as we explore:Everything about metabolism - what it is, how it works, can it be “slow” or “fast”, why it becomes dysfunctional and the most important signals of sub-optimal metabolism.An incredible study that exposes the “I'm getting old equals weight gain” myth, and why you can actually have the same metabolism at 90 as you had in your 20s.Fasting insulin, why it's critically important in metabolism and the difference between being metabolically free and being an imprisoned “sugar burner”. The scientifically-proven power of “vitamin G”.Ben's top biohacks to bolster metabolism.Contact:Website: www.benazadi.com Instagram: @thebenazadi Mention:Study - Pontzer H, et al,. Daily energy expenditure through the human life course. Science. 2021 Aug 13;373(6556):808-812. doi: 10.1126/science.abe5017. PMID: 34385400; PMCID: PMC8370708. Study - Kobayashi LC, Hagan KA, Trudel-Fitzgerald C, et al.Gratitude and Mortality Among Older US Female Nurses.JAMA Psychiatry. Published online July 3, 2024. doi:10.1001/jamapsychiatry.2024.1610Study - Picard M, Prather AA, Puterman E, Cuillerier A, Coccia M, Aschbacher K, Burelle Y, Epel ES. A Mitochondrial Health Index Sensitive to Mood and Caregiving Stress. Biol Psychiatry. 2018 Jul 1;84(1):9-17. doi: 10.1016/j.biopsych.2018.01.012. Epub 2018 Feb 3. PMID: 29525040; PMCID: PMC6014908.Support the showFollow Steve's socials: Instagram | LinkedIn | YouTube | Facebook | Twitter | TikTokSupport the show on Patreon:As much as we love doing it, there are costs involved and any contribution will allow us to keep going and keep finding the best guests in the world to share their health expertise with you. I'd be grateful and feel so blessed by your support: https://www.patreon.com/MadeToThriveShowSend me a WhatsApp to +27 64 871 0308. Disclaimer: Please see the link for our disclaimer policy for all of our content: https://madetothrive.co.za/terms-and-conditions-and-privacy-policy/
In this world where the inner teachings of spirituality are held inside secret sanctums, we have to be ready and willing to hear them and to affect change in our own lives. Without a clear understanding of spiritual concepts the waters of life get muddy with the muck of the outer world.Put on your headphones and join me for a Higher Consciousness Walk where we delve into some questions where the answers can be a little unclear. Turn on your psychic senses and ask for any additional guidance and wisdom as it pertains to your own situation.THANKS FOR Being here
Send us Fan MailThyroid Talk with Dr. Angela Mazza, DOShow Notes Episode 50; Recorded: August 8, 2026The Iron Paradox: Iron, Thyroid Health, and FerroptosisHost: Dr. Angela Mazza, DOCo-host: Dawn Sheffield I'm Dr. Angela Mazza, D.O., a thyroid, endocrine, and metabolism specialist with a private practice in Central Florida. My goal for this podcast is to define and demystify the thyroid gland, and thyroid-related medical conditions. By providing information in an easy-to-understand format, we hope to help patients better understand the ways in which their bodies work, and to help them thrive. My goal is to help us live more fulfilling lives by taking control of our health, to feel our best. I do this podcast to provide life-saving education and encourage patients to see a doctor in time to prevent or minimize damage. That's deeply fulfilling. I enjoy helping folks understand how all aspects of their lives are tied to both thyroid and overall health. That's why I went into endocrinology. It's a medical art that combines science with the study of our lives—and all that they encompass. Here's some of what we covered in episode 50, not necessarily in this order: · Iron is involved in some of the most fundamental processes in human physiology.· What is ferroptosis? Is it science fiction--or science fact?· Iron may play a big role in inflammation, oxidative stress, aging biology, & longevity.· Iron is an essential mineral that the body requires for survival.· Iron helps us form hemoglobin--the protein in red blood cells that carries oxygen throughout the body.· When iron levels are inadequate, cells may struggle to produce energy efficiently.· Symptoms of low iron may mimic those of hypo--that is, low--thyroid. · Iron deficiency can directly affect thyroid physiology itself.· Who tends to be most vulnerable to iron deficiency?· And best of all we learned that we CAN impact our thyroid health!My book, Thyroid Talk: An Integrative Guide to Optimal Thyroid Health, is available on Amazon. Visit the Wellness Store at metaboliccenterforwellness.com regarding supplements mentioned in various episodes of this podcast. Please stay in touch! Send your comments, show ideas, and questions to thyroidtalk.mazza@gmail.com We may disclose your general location on air (the city or town, for example), but we will not read your name nor your address on the show. We reserve the right to edit your input as necessary. See the website at metaboliccenterforwellness.com; our YouTube channel (Dr. Angela Mazza), Facebook, and Instagram. Ask your healthcare provider about specific questions regarding your wellness. This podcast is meant for educational purposes only. Citations, references, additional information:Mazza AD. Iron at the Crossroads of Thyroid Function and Detoxification in Women: Clinical Implications for Diagnosis and Management. Integr Med (Encinitas). 2026 Jun;25(3):15-21. PMID: 42491815; PMCID: PMC13377770.Mazza AD. Thyroid Hormones and Aging: Modulators of Mitochondrial Health, Metabolic Flexibility, and Longevity Pathways. Horm Metab Res. 2026 Feb;58(2):50-55. doi: 10.1055/a-2698-0521. Epub 2025 Sep 8. PMID: 40921197.Mazza A. Thyroid Talk: An Integrative Guide to Optimal Thyroid Health. Available now on Amazon.Copyright 2026 Dr. Angela Mazza DO. Thyroid Talk with Dr. Angela Mazza, DO. All rights reserved.Check out our YouTube channel - Dr. Angela Mazza, our website at Metabolic Center for Wellness, our FaceBook and our Instagram page.
Ryan Coleman, MD is an Associate Professor of Pediatrics at Baylor College of Medicine with dual appointments in Critical Care Medicine and Pulmonary Medicine at Texas Children's Hospital in Houston. He earned his medical degree from the University of Texas Health Science Center at San Antonio School of Medicine, completed pediatric residency and pediatric critical care fellowship training at Baylor College of Medicine, and holds additional training in pediatric bioethics. Dr. Coleman is board-certified in general pediatrics and pediatric critical care medicine and focuses his clinical and research efforts on pediatric extracorporeal membrane oxygenation (ECMO), severe pulmonary hypertension and right heart failure, and bioethical issues in critically ill children.Learning Objective: By the end of this podcast, listeners should be able to discuss an evidence-based and expert-guided approach to the hemodynamic resuscitation of a child with high-risk pulmonary embolism and acute right heart failure.References:Ross C, Kumar R, Pelland-Marcotte MC, Mehta S, Kleinman ME, Thiagarajan RR, Ghbeis MB, VanderPluym CJ, Friedman KG, Porras D, Fynn-Thompson F, Goldhaber SZ, Brandão LR. Acute Management of High-Risk and Intermediate-Risk Pulmonary Embolism in Children: A Review. Chest. 2022 Mar;161(3):791-802. doi: 10.1016/j.chest.2021.09.019. Epub 2021 Sep 26.Monagle P, Cuello CA, Augustine C, Bonduel M, Brandão LR, Capman T, Chan AKC, Hanson S, Male C, Meerpohl J, Newall F, O'Brien SH, Raffini L, van Ommen H, Wiernikowski J, Williams S, Bhatt M, Riva JJ, Roldan Y, Schwab N, Mustafa RA, Vesely SK. American Society of Hematology 2018 Guidelines for management of venous thromboembolism: treatment of pediatric venous thromboembolism. Blood Adv. 2018 Nov 27;2(22):3292-3316. doi: 10.1182/bloodadvances.2018024786.Send us Fan MailSupport the showHow to support PedsCrit:Please complete our Listener Feedback SurveyPlease rate and review on Spotify and Apple Podcasts!Donations are appreciated @PedsCrit on Venmo , you can also support us by becoming a patron on Patreon. 100% of funds go to supporting the show.Please remember that all content during this episode is intended for educational and entertainment purposes only. It should not be used as medical advice. The views expressed during this episode by hosts and our guests are their own and do not reflect the official position of their institutions. If you have any comments, suggestions, or feedback-you can email us at pedscritpodcast@gmail.com. You can also check out our website at http://www.pedscrit.com. Thank you for listening to this episode of PedsCrit!
En este episodio Any reseña una novela de Stephen Graham Jones, un libro que estuvo muy comentado en redes sociales por ejemplo, en instagram y que causó controversia por el estilo narrativo del libro. En este libro se encuentran varios temas delicados como: el racismo, la violencia contra los animales, como viven los nativos americanos y mucho mas. La novela cuenta la historia de cuatro amigos jovenes que se meten en un gran lio al cazar siervos en una zona reservada para los adultos mayores de una reserva nativa americana. Son descubiertos por el guardia y deben abandonar ese lugar sagrado. Sin embargo, pasan los años y misteriosamente a los amigos empiezan a morir uno a uno. Algo los esta acechando buscando venganza por los acontecimientos del pasado. Consigue el libro digital mediante este enlace: El único indio bueno - Stephen Graham JonesComéntanos que te ha parecido este episodio, ¿lo has leído?. Recuerda dejarnos una calificación en Spotify o en Apple Podcasts.También tenemos mas contenido por esta plataforma. Patreon: https://www.patreon.com/MentesliteralesPuedes invitarnos un café ☕️ o un libro
Episode No. 772 features art historians Zanna Gilbert and Andrew Perchuk; and curator Meg Linton, museum director Taras Matla, and associate museum director Steve Comba. Along with Emily Pugh, Gilbert and Perchuk are the project leads for "Ed Ruscha's Streets of Los Angeles," a Getty Research Institute project that has, among other things, digitized Ed Ruscha's five-decade-long photographic project to document the streets of Los Angeles. The GRI project also considers Ruscha's Streets of Los Angeles archive within a range of historical frameworks, spotlights what it tells us about modern and contemporary art, architecture, and the physical, social, and cultural geographies of Los Angeles. GRI-produced websites include: "Artist, Image, Archive, City," a free digital book featuring visualizations, essays, images and more (the book is also available in free PDF and EPUB formats); "12 Sunsets," which features Ruscha's famed photos of the Sunset Strip, including how the street has changed over the last 50 years; The Ed Ruscha's Streets of Los Angeles Archive at the GRI; Research Collections Viewer for Ruscha's photographs of Sunset Boulevard and Hollywood Boulevard; Research Collections Viewer for Ruscha's photographs of (other) Los Angeles streets; Digitized images from the collection. On the second segment, we discuss the dispersal of artist Steve Roden's estate with curator Meg Linton, who has advised the estate, University of Maryland Art Gallery director Taras Matla, and Benton Museum of Art at Pomona College associate director Steve Comba. Roden was a Los Angeles-area-based artist who worked in sound, sculpture, painting, and other media, who passed away in 2023 at the age of 59. The Roden estate has recently dispersed works to museums all over the United States, including those represented on this week's program, as well as to the Grunwald Center at the Hammer Museum, the Los Angeles County Museum of Art, the Museum of Contemporary Art, Los Angeles, the UC Irvine Langson Orange County Museum of Art, Ruby City, San Antonio, and more. Roden created sound for The MAN Podcast in 2011. Air date: August 20, 2026.
Today, we are taking a deep dive into a medical truth thatsounds completely counterintuitive, almost upside down, based on everything you think you know about women's health. But here's the kicker: it's actually nothing new at all. For over two decades, ever since the landmark Women'sHealth Initiative (WHI) study made global headlines back in 2002, the blanket narrative surrounding menopausal hormone therapy has been clear and persistent: hormones equal breast cancer risk. But there is a massive asterisk in thatscience that got completely lost in the media noise. While combination therapy with conjugated equine estrogens paired with medroxyprogesterone acetate (CEE +MPA) did show an increased risk, the story for estrogen-only therapy (mainly CEE) in women wh had a hysterectomy is entirely different. In fact, an overwhelming mountain of growing data shows that estrogen-only therapy is protectiveagainst both breast cancer incidence and breast cancer mortality. In this episode, we're unpacking the latest high-level evidence that cements this crucial distinction. We'll examine the broad statistical landscape, including a comprehensive meta-analysis by Qing et al. (officially set for the December 2026 issue of Annals of Medicine, following its ahead-of-print release in March 2026). Their work breaks down how randomized controlled trial data consistentlypoint to estrogen-only therapy having a protective effect, in stark contrast to combination therapy. We'll also dive into a brand-new Clinical Perspective published in mid-August 2026 in Obstetrics & Gynecology (the Green Journal) by Drs. Andrew Kaunitz and Jason Wright. They call urgent attention to this phenomenon, highlighting RCT meta-analyses that demonstrate a 23% reduction in breast cancer incidence with estrogen alone (RR = 0.77), alongside striking cohort data showing a dramatic risk reduction even in high-risk populations, like carriers of the BRCA mutation. Listenin for details.1. Wu Q, Shen L, Hu S, Yang R, Wang Y, Xue D, SunY, Ma H, Dai Z. Relationship between menopausal hormone therapy and incidencerisk of breast cancer: systematic review and meta-analysis. Ann Med. 2026Dec;58(1):2640244. doi: 10.1080/07853890.2026.2640244. Epub 2026 Mar.2. Kaunitz, Wright. Menopausal Estrogen Therapy andRisk of Breast Cancer. Obstet Gynecol. Aug 20263. Chlebowski RT, Aragaki AK, Pan K, et al.Randomized Trials of Estrogen-Alone and Breast Cancer Incidence: AMeta-Analysis. Breast Cancer Research and Treatment. 2024. 4. Writing Group for the Women's Health InitiativeInvestigators. (2002). Risks and benefits of estrogen plus progestin in healthypostmenopausal women: Principal results from the Women's Health Initiativerandomized controlled trial. JAMA, 288(3), 321–333.
Hi everyone Dexmedetomidine, is both a difficult word to pronounce correctly in casual conversation but also a useful pharmacological tool in many different situations. This week I am joined by one of our fellows Dr Han Lu to discuss dexmedetomidine, it’s history, it’s basic pharmacology and then more specifically it’s use in different clinical situations where it may be useful in obstetrics and gynaecology. Thanks Han for a great Tuesday talk and a very informative podcast! References Han’s powerpoint talk Effectiveness of dexmedetomidine on patient-centred outcomes in surgical patients: a systematic review and Bayesian meta-analysis. BJA September 2024 Crowe. G, et al Perioperative Applications of Dexmedetomidine. ATOTW 469 — Perioperative Applications of Dexmedetomidine April 2022 Douglas MS, Soloniuk LJ, Jones J, Derderian R, Baker C, Stier G. Intravenous dexmedetomidine use in obstetric anesthesia: a focused review. Int J Obstet Anesth. 2025 May;62:104345. doi: 10.1016/j.ijoa.2025.104345. Epub 2025 Feb 13. PMID: 40090158 Atipamezole – alpha 2 agonist reversal agent used in veterinary practice
En este episodio nos adentramos en la atmósfera oscura e inquietante de Ese no es mi nombre, la electrizante novela de suspenso de la autora Megan Lally.La historia arranca con una pesadilla desgarradora: una joven despierta a un lado de la carretera, magullada, ensangrentada y sin ningún recuerdo de quién es o cómo llegó allí. Cuando un hombre desesperado llega a la comisaría asegurando ser su padre y llamándola "Mary", parece que la pesadilla ha terminado y que está a salvo. Ella pensaba que había recuperado su vida... pero estaba gravemente equivocada.A medida que "Mary" intenta encajar en una casa que no le resulta familiar y con un padre que actúa cada vez más extraño, la tensión se dispara. Paralelamente, conocemos la historia de Drew, un chico que busca desesperadamente a su novia desaparecida, Lola. ¿Cómo se cruzan estas dos vidas? Analizamos las pistas, las identidades robadas y los giros escalofriantes de este thriller que no te deja soltar el libro.Consigue el libro en Amazon: Ese no es mi nombre - Megan Lally¿Qué harías si despiertas sin recordar nada y sientes que la persona que cuida de ti te está mintiendo? Si ya leíste la novela, ¿lograste adivinar el giro principal antes de tiempo? Déjanos tus comentarios en nuestras redes sociales o en tu plataforma de podcasts favorita. ★ Support this podcast on Patreon ★
Chuck and Chris review 6 recent Journal of Hand Surgery articles with a variety of topics. Tune in and see below.1) Arends GR, van Kooij YE, Stern BZ, Hovius SER, Wouters RM; Hand-Wrist Study Group; de Ridder WA. Understanding Why Certain Patients With Hand and Wrist Conditions Are Dissatisfied Despite Achieving Their Expressed Personal Improvement Goals Anchored at Satisfaction: A Qualitative Study. J Hand Surg Am. 2026 Jun;51(6):687-697. doi: 10.1016/j.jhsa.2025.12.009. Epub 2026 Jan 29. PMID: 41609542.2) Lee SH, Kim MB, Lee YH. Surgical Management of Delayed Mallet Finger Fractures Using Combined Two-Extension Block Kirschner Wire and Dorsal Counterforce Techniques. J Hand Surg Am. 2026 May;51(5):555-563. doi: 10.1016/j.jhsa.2025.12.019. Epub 2026 Jan 29. PMID: 41609545.3) Lunasin RM, Capell W, Kaufman KR, Shin AY. Rethinking Muscle Testing: Dynamic EMG Studies of Elbow Positioning as a Differentiator of Pronator Teres and Quadratus Functions. J Hand Surg Am. 2026 Apr;51(4):437.e1-437.e8. doi: 10.1016/j.jhsa.2025.09.013. Epub 2025 Oct 29. PMID: 41159989.4) Morisaki S, Yoshii K, Tsuchida S, Oda R, Takahashi K. Comparison of Manual Tie and Knotless Suture Anchor Techniques in Arthroscopic Transosseous Foveal Repair of the Triangular Fibrocartilage Complex. J Hand Surg Am. 2026 May;51(5):503-510. doi: 10.1016/j.jhsa.2026.01.021. Epub 2026 Mar 4. PMID: 41778936.5) Mwangi J, Henriquez AR, Varney CR, Yu R, Kim JK, Baker RL Jr, Pidgeon T, Hammert WC. Suture-Button Suspensionplasty Does Not Provide a Sustained Functional Advantage Over Ligament Reconstruction and Tendon Interposition for Thumb Carpometacarpal Arthritis. J Hand Surg Am. 2026 Jun;51(6):623-630. doi: 10.1016/j.jhsa.2026.02.019. Epub 2026 Apr 3. PMID: 41934451.6) Surke C, Del Rosario PA, Huntington LS, Ek ETH, Tham SK, Ackland D. Fracture Fixation in an Unstable Scaphoid Fracture Model: A Biomechanical Comparison of Double Screw Osteosynthesis With Two Common Bone Graft and Fixation Techniques. J Hand Surg Am. 2026 Apr;51(4):391.e1-391.e8. doi: 10.1016/j.jhsa.2025.09.007. Epub 2025 Oct 25. PMID: 41137815.See www.practicelink.com/theupperhand for more information from our partner on job search and career opportunities.The Upper Hand Podcast is sponsored by Checkpoint Surgical, a provider of innovative solutions for peripheral serve surgery. To learn more, visit https://checkpointsurgical.com/.As always, thanks to @iampetermartin for the amazing introduction and concluding music.For additional links, the catalog. Please see https://www.ortho.wustl.edu/content/Podcast-Listings/8280/The-Upper-Hand-Podcast.aspx
Send us Fan MailThe full week of Journal Club in one place. Monday, the PLaNT trial of prophylactic CPAP for late preterm infants born by cesarean, with senior author Dr. Edgardo Szyld. Tuesday, whether parental holding during therapeutic hypothermia changes feeding and length of stay. Wednesday, the Connection Study, the first live biotherapeutic product tested under an IND, and what it means for probiotics returning to the NICU. Thursday, a handheld light probe that reads bowel through the skin to catch NEC before the X-ray does. Friday, Dr. Dinushan Kaluarachchi on the respiratory severity score and what its trajectory tells us.----First-in-human pilot study of broadband optical spectroscopy (BOS) as noninvasive surveillance for necrotizing enterocolitis (NEC). Dodd AC, Lehane AJ, Lee A, Hurlock A, Su Y, Ilahi I, Lautz TB, Backman V, Goldstein SD.J Pediatr Surg. 2026 May;61(5):162978. doi: 10.1016/j.jpedsurg.2026.162978. Epub 2026 Feb 3.PMID: 41643767Association of parental holding during therapeutic hypothermia and NICU outcomes for infants with hypoxic-ischemic encephalopathy. Nguyen TT, Glass HC, Chan N, Taketa E, Pineda R, Cornet MC, Miller MJ.J Perinatol. 2026 Jun 22. doi: 10.1038/s41372-026-02753-3. Online ahead of print.PMID: 42332041Live biotherapeutic product IBP-9414 (L. reuteri) in very low birth weight infants: the Connection Study. Neu J, Del Moral T, Guthrie SO, Hudak ML, Indrio F, Kim JH, Kronström A, Martin CR, Modi N, Rastad J, Schnitzer TJ, Singh R, Strömberg S, Szajewska H, Thuresson M, Caplan M.Pediatr Res. 2026 Feb 20. doi: 10.1038/s41390-026-04826-7. Online ahead of print.PMID: 41721054Prophylactic CPAP at Cesarean Birth in Late-Preterm Newborns: A Multicenter RCT. Shah BA, DeShea L, Schmölzer GM, Josephsen JB, Fabres J, Wetzel EA, Rykovich H, Thomas A, Law B, Garrido C, Szyld E.Pediatrics. 2026 Aug 1;158(2):e2025070998. doi: 10.1542/peds.2025-070998.PMID: 42457181 Clinical Trial.Association Between Delivery Room Continuous Positive Airway Pressure and Neonatal Outcomes in Late Preterm and Term Infants: A Systematic Review and Meta-Analysis. Chin Y, Hill M, Sett A, Thomas N, Razak A.J Paediatr Child Health. 2026 Jul 28. doi: 10.1111/jpc.70516. Online ahead of print.PMID: 42517258 Review.Bronchopulmonary Dysplasia Definition Based on Respiratory Severity Score. Kaluarachchi DC, Peebles PJ, Lasarev MR, Guthrie SO, Laughon MM.Pediatr Pulmonol. 2026 Jul;61(7):e71750. doi: 10.1002/ppul.71750.PMID: 42478108 Free PMC article. No abstract available.Respiratory severity score patterns by birth gestational age among a cohort of extremely preterm infants. Peebles PJ, Lasarev MR, Guthrie SO, Laughon MM, Keller RL, Kaluarachchi DC.J Perinatol. 2026 Jun 29. doi: 10.1038/s41372-026-02778-8. Online ahead of print.PMID: 42374145 No abstract available.Respiratory severity score as a predictor for need for tracheostomy in infants with severe bronchopulmonary dysplasia. Kaluarachchi NM, Afah Annah S, Lasarev MR, Peebles PJ, Kaluarachchi DC.J Perinatol. 2026 Jun 25. doi: 10.1038/s41372-026-02720-y. Online ahead of print.PMID: 42350618 No abstract available.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!
Send us Fan MailNEC still tends to announce itself on an X-ray, usually later than we want. This week Daphna reviews the first-in-human study of broadband optical spectroscopy, a handheld transcutaneous probe out of Lurie Children's that reads reflected light from 350 to 2500 nanometers to look at bowel beneath the skin. Just under 100 preterm infants, more than 11,000 scans, and a machine learning model that separated NEC from non-NEC scans with 100% sensitivity and a 100% negative predictive value, though the positive predictive value sat at 24%. Ben and Daphna work through what the curves actually show and what would have to come next.----First-in-human pilot study of broadband optical spectroscopy (BOS) as noninvasive surveillance for necrotizing enterocolitis (NEC). Dodd AC, Lehane AJ, Lee A, Hurlock A, Su Y, Ilahi I, Lautz TB, Backman V, Goldstein SD.J Pediatr Surg. 2026 May;61(5):162978. doi: 10.1016/j.jpedsurg.2026.162978. Epub 2026 Feb 3.PMID: 41643767Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!
Today on the Yoga Medicine Podcast, Tiffany Cruikshank and co-host Katja Bartsch explore the latest research on strength training during pre- and post-menopause. Using a newly published systematic review and meta-analysis of 126 studies involving more than 4,000 women, they unpack what the evidence actually says about building strength and improving body composition in different stages of reproductive aging. Together, Tiffany and Katja separate common myths from current research, discussing progressive overload, lean muscle, body composition, estrogen, and why strength gains remain possible well into midlife and beyond. They also explore why consistency and enjoyment may be just as important as the specific type of resistance training you choose, offering practical takeaways for yoga practitioners, teachers, and anyone looking to age well. "When we intervene, when we start to create a plan... the capacity to build strength is the same." — Tiffany Cruikshank. — What You'll Learn: Overview of the latest research on strength training across the female lifespan [01:25] Why strength gains remain possible after menopause [08:47] Body composition changes with strength training [16:25] Why enjoyment and consistency are key to long-term success [21:36] Current research gaps and unanswered questions [27:07] Shifting the focus from weight loss to feeling and functioning your best [31:08] How yoga complements strength training for lifelong health [32:34] — Links Mentioned: Watch this episode on YouTube Isenmann E, Geisler S, Havers T, Siegert F, Hemke F, Held S. It's never too late: The impact of resistance training on strength and body composition in females across the lifespan - A systematic review and meta-analysis. J Sci Med Sport. 2026 Mar 18:S1440-2440(26)00096-4. doi: 10.1016/j.jsams.2026.03.002. Epub ahead of print. PMID: 41963141. — Learn More: Find the full show notes at YogaMedicine.com/podcast-173. Learn more about insider tips, online classes or information on our teacher trainings at YogaMedicine.com. To support our work, please leave us a 5 star review with your feedback on iTunes/Apple Podcasts or wherever you listen to podcasts.
What does it take to go from astrophysics to running operations at one of the fastest-growing AI companies in the world?In this Fan Favorite episode, Cameron Herold sits down with Victoria Weller, former Chief of Staff and now Lead of Operations at ElevenLabs, to revisit one of the show's most fascinating conversations. Victoria's path is rare: astrophysics, space medicine, quantum encryption, and Palantir, before landing at the AI voice company reshaping how the world listens.She breaks down what a Chief of Staff really does at an early-stage startup, how she cleared SOC 2 compliance in seven weeks, and why ElevenLabs grew so fast. They also get into voice cloning, deepfake safeguards, and surprising use cases across hospitals, transit, and accessibility.Whether you want a COO seat or you are building functions from nothing, Victoria's story is a masterclass in figuring it out fast. Listen now.Sponsored by:Redirect Health - Affordable healthcare benefits designed to make traditional insurance optional, with 24/7 access to primary care and Rx support that helps businesses reduce costs while keeping employees covered.Learn more: http://www.redirectcoo.com/Timestamped Highlights[00:00:44] – The ElevenLabs mission, and why an EPUB can become an instant audiobook[00:02:55] – Munich to Edinburgh to Berlin to New York: a career across four countries[00:04:06] – What actually happens to an astronaut's blood in zero gravity[00:07:54] – Lasers, quantum encryption, and the pivot toward tech[00:13:06] – Cameron asks the big ones: aliens, and are we living in a simulation?[00:19:12] – What ElevenLabs is really building, explained simply[00:20:50] – How context lets an AI voice sound genuinely sad or genuinely happy[00:28:12] – The accessibility use cases the team never saw coming[00:31:03] – Cloning a late loved one's voice, and the compliance behind it[00:33:16] – Stopping deepfake voice scams: watermarks and the AI Speech Classifier[00:38:31] – What a Chief of Staff actually does, and why it feels like a SWAT team[00:40:32] – Does a great Chief of Staff work themselves out of a job?[00:47:07] – The advice Victoria would give her 21-year-old selfAbout the GuestVictoria Weller is the former Chief of Staff and now the Lead of Operations at ElevenLabs, the AI voice company behind lifelike text-to-speech and voice cloning, where she owns internal operations, compliance, and hiring. She cleared the company's SOC 2 process in seven weeks. Before ElevenLabs she was a reliability engineer at Palantir Technologies in New York and London. Her background spans astrophysics at the University of Edinburgh, space-medicine research in Berlin, and a master's in applied physics from Columbia University.
Digital surgery has morphed from buzzword into ubiquitous high-impact technology. In this episode, the BTK MIS team steps into the rapidly evolving ecosystem of cameras, sensors, robotics, and software that are turning surgical operations into structured, analyzable datasets. From AI segmentation to real-time telepresence, don't miss this opportunity to catch up on what's new and what's next, what's exciting and what's terrifying, just on the horizon of your surgical career. Hosts: · James Jung, MD, PhD, Assistant Professor of Surgery, Duke University· Jacob Greenberg, MD, EdM, MIS Division Chief and Vice Chair for Education, Duke University· Zachary Weitzner, MD, Minimally Invasive and Bariatric Surgery Fellow, Duke University, @ZachWeitznerMD· Joey Lew, MD, MFA, Surgical resident PGY-3, Duke University, @lew__actuallyLearning Goals: By the end of this episode, listeners will be able to:· Define “digital surgery” and describe its core components, including video capture, instrumentation, robotics, data analytics, and system connectivity. · Discuss current and emerging applications of digital surgery in surgical education, including video-based self-assessment, procedural segmentation, and structured feedback models. · Describe how digital tools can be used to improve OR efficiency and resource utilization, including instrumentation usage, operative time analysis, and workflow optimization. · Summarize current telepresence and teleproctoring technologies and their clinical use cases, including augmented reality–based collaboration across institutions and geographic boundaries. · Identify key ethical, legal, and operational challenges in digital and tele-surgery, including credentialing, cross-state licensure, liability, and trust in remote expertise. · Discuss how digital surgery may reshape surgical training and competency-based assessment, including implications for autonomy, deliberate practice, and feedback frequency. · Recognize future directions of digital surgery integration, including predictive analytics, simulation using patient-specific imaging, and AI-assisted intraoperative decision support.References: Balvardi S, Semsar-Kazerooni K, Kaneva P, et al. Validity of video-based general and procedure-specific self-assessment tools for surgical trainees in laparoscopic cholecystectomy. Surg Endosc. 2023;37(3):2281-2289. doi:10.1007/s00464-022-09466-6 [https://pubmed.ncbi.nlm.nih.gov/36307525/] Hospital Utilizes Intraoperative Idle Time Metrics to Improve Surgical Safety and Efficiency. Theator | The Surgical Intelligence Company. Accessed March 20, 2026. https://theator.io/customer-story/hospital-utilizes-intraoperative-idle-time-metrics-to-improve-surgical-safety-and-efficiency/ Campbell KK, Abreu AA, Zeh HJ, et al. Using OR Black Box Technology to Determine Quality Improvement Outcomes for In-situ Timeout and Debrief Simulation. Ann Surg. 2026;283(1):122. doi:10.1097/SLA.0000000000006438 [https://pubmed.ncbi.nlm.nih.gov/38317208/] Al Abbas AI, Meier J, Daniel W, et al. Impact of team performance on the surgical safety checklist on patient outcomes: an operating room black box analysis. Surg Endosc. 2024;38(10):5613-5622. doi:10.1007/s00464-024-11064-7 [https://pubmed.ncbi.nlm.nih.gov/39069926/] Proximie's telepresence platform helps surgeons across the globe grow and exchange experience in real-time. World Health Expo Insights. Accessed March 20, 2026. https://www.worldhealthexpo.com/insights/telemedicine/proximie-s-telepresence-platform-helps-surgeons-across-the-globe-grow-and-exchange-experience-in-real-time Hassan AE, Desai SK, Georgiadis AL, Tekle WG. Augmented reality enhanced tele-proctoring platform to intraoperatively support a neuro-endovascular surgery fellow. Interv Neuroradiol. 2022;28(3):277-282. doi:10.1177/15910199211035304 [https://pubmed.ncbi.nlm.nih.gov/34538166/] SAGES Digital Surgery Working Group; Ali JT, Yang G, Green CA, Reed BL, Madani A, Ponsky TA, Hazey J, Rothenberg SS, Schlachta CM, Oleynikov D, Szoka N. Defining digital surgery: a SAGES white paper. Surg Endosc. 2024 Feb;38(2):475-487. doi: 10.1007/s00464-023-10551-7. Epub 2024 Jan 5. PMID: 38180541. [https://pubmed.ncbi.nlm.nih.gov/38180541/] Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more. If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listenBehind the Knife Premium: https://behindtheknife.org/premiumOral Board Review: https://behindtheknife.org/oral-boardOral Board Simulator: https://behindtheknife.org/oral-board/simulatorGeneral Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-reviewTrauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlasDominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkshipDominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotationVascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-reviewColorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-reviewSurgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-reviewCardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-reviewOBGYN Oral Board Review Coures: https://behindtheknife.org/course/obgyn-oral-board-reviewEPA Playbook: https://behindtheknife.org/course/epa-playbookSurgical Instrument Flashcards: https://behindtheknife.org/course/surgical-instrument-flashcardsABSITE Review: https://behindtheknife.org/course/absite-2026-exam-reviewDownload our App:Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US
Dr. Kurt Olding shares with us the latest published recommendations for conservative treatment for spinal stenosis. Dr. Kurt Olding has been in practice for over 40 years, opening Minster Chiropractic Center in 1986 after graduating from National College of Chiropractic in Lombard, IL in 1984. Through the years Dr. Kurt has enjoyed treating all age groups, from infants to athletes and parents to grandparents. He took special interest in sports medicine during his early years in practice, completing 300 hours of continuing education through the Certified Chiropractic Sports Physician program. Dr. Kurt earned Cox® Technic certification in 2009. In 2012 he began co-instructing the technique, and since 2015 has been a full-time instructor alongside Dr. James Cox, Dr. Ralph Kruse, and Dr. George Joachim. Through his work with Cox® Technic, Dr. Kurt has had several exciting opportunities. In March of 2016, he taught Cox® Technic in Bern, Switzerland as part of the Swiss Chiropractic Academy's "technique series" program. Later that month, he presented research on Cox® Technic with his mentor Dr. James Cox at the annual Association of Chiropractic Colleges Research Agenda Conference. Dr. Kurt co-authored a paper published in the June 2016 edition of the Journal of Chiropractic Medicine titled Chiropractic Distraction Spinal Manipulation on Post-surgical Continued Low Back and Radicular Pain patients: A Retrospective Case Series. In 2015, Dr. Kurt became board certified as a Chiropractic Orthopedist, and a Fellow of the Academy of Chiropractic Orthopedists (FACO). He is also a board member of the Academy of Chiropractic Orthopedists, serving since early 2016. Dr. Kurt and his wife Jackie are Minster natives. They have three children: Sunni, Kregg, and Jack. Sunni and her husband Tyler joined the practice in 2014. Resources: Minster Chiropractic Center kurt.olding@gmail.com Find a Back Doctor thebackdoctorspodcast.com The Cox 8 Table by Haven Medical References: Young I, Dunning J, Butts R, Bliton P, Zacharko N, Garcia J, Mourad F, Charlebois C, Gorby P, Fernández-de-Las-Peñas C. Spinal manipulation and electrical dry needling as an adjunct to conventional physical therapy in patients with lumbar spinal stenosis: a multi-center randomized clinical trial. Spine J. 2024 Apr;24(4):590-600. doi: 10.1016/j.spinee.2023.12.002. Epub 2023 Dec 14. PMID: 38103739. Ammendolia C, Hofkirchner C, Plener J, Bussières A, Schneider MJ, Young JJ, Furlan AD, Stuber K, Ahmed A, Cancelliere C, Adeboyejo A, Ornelas J. Non-operative treatment for lumbar spinal stenosis with neurogenic claudication: an updated systematic review. BMJ Open. 2022 Jan 19;12(1):e057724. doi: 10.1136/bmjopen-2021-057724. PMID: 35046008; PMCID: PMC8772406. Schneider MJ, Ammendolia C, Murphy DR, Glick RM, Hile E, Tudorascu DL, Morton SC, Smith C, Patterson CG, Piva SR. Comparative Clinical Effectiveness of Nonsurgical Treatment Methods in Patients With Lumbar Spinal Stenosis: A Randomized Clinical Trial. JAMA Netw Open. 2019 Jan 4;2(1):e186828. doi: 10.1001/jamanetworkopen.2018.6828. PMID: 30646197; PMCID: PMC6324321. Bussières A, Cancelliere C, Ammendolia C, Comer CM, Zoubi FA, Châtillon CE, Chernish G, Cox JM, Gliedt JA, Haskett D, Jensen RK, Marchand AA, Tomkins-Lane C, O'Shaughnessy J, Passmore S, Schneider MJ, Shipka P, Stewart G, Stuber K, Yee A, Ornelas J. Non-Surgical Interventions for Lumbar Spinal Stenosis Leading To Neurogenic Claudication: A Clinical Practice Guideline. J Pain. 2021 Sep;22(9):1015-1039. doi: 10.1016/j.jpain.2021.03.147. Epub 2021 Apr 12. PMID: 33857615. Comer C, Williamson E, McIlroy S, Srikesavan C, Dalton S, Melendez-Torres GJ, Lamb SE. Exercise treatments for lumbar spinal stenosis: A systematic review and intervention component analysis of randomised controlled trials. Clin Rehabil. 2024 Mar;38(3):361-374. doi: 10.1177/02692155231201048. Epub 2023 Sep 16. PMID: 37715644; PMCID: PMC10829420. Bise CG, Schneider M, Freburger J, Fitzgerald GK, Switzer G, Smyda G, Peele P, Delitto A. First Provider Seen for an Acute Episode of Low Back Pain Influences Subsequent Health Care Utilization. Phys Ther. 2023 Sep 1;103(9):pzad067. doi: 10.1093/ptj/pzad067. PMID: 37379349. Hernandez-Martínez J, Cid-Calfucura I, Vásquez-Carrasco E, Perez-Carcamo J, Herrera-Valenzuela T, Aravena-Sagardia P, Barramuño-Medina M, Valdés-Badilla P. Timed Up-and-Go as a predictor of fracture risk: a systematic review and meta-analysis in a population of over 1.6 million people. Front Public Health. 2026 May 11;14:1841017. doi: 10.3389/fpubh.2026.1841017. PMID: 42200137; PMCID: PMC13199231. Henn MC, Rae A, Fecker AL, McIntyre M, Larsen A, Wright J. A Nationwide Survey of the Spine Education of Medical Students. Cureus. 2026 Apr 4;18(4):e106443. doi: 10.7759/cureus.106443. PMID: 42093772; PMCID: PMC13139429. James G, Ahern B, Goodwin W, Goss B, Hodges P. ISSLS Prize in Basic Science 2025: Structural changes of muscle spindles in the multifidus muscle after intervertebral disk injury are resolved by targeted activation of the muscle. Eur Spine J. 2025 May;34(5):1600-1613. doi: 10.1007/s00586-025-08646-x. Epub 2025 Jan 15. Erratum in: Eur Spine J. 2025 May;34(5):2046. doi: 10.1007/s00586-025-08744-w. PMID: 39810036. Gong G, Yan Z, Lai Q, You P, Yu P, Li X, Wang Z, Lin S, Dai Y, Jiang H, Liu J. Inflammation preservation strategy: reconciling pain control and disc resorption in lumbar disc herniation. Front Immunol. 2025 Sep 2;16:1653681. doi: 10.3389/fimmu.2025.1653681. PMID: 40963597; PMCID: PMC12436131.
Welcome to the latest episode (August 2026) of DOC Updates, where every month Neil Skolnik, MD and John Russell, MD review the most important articles on diabetes, obesity, and cardiometabolic disease. This month on DOC Updates: Hirsh Elhence, Jennifer L. Dodge, Stephen Fuest, et al. National Prevalence of Clinical Obesity by BMI Class: A National Cross-Sectional Study. Ann Intern Med. [Epub 2 June 2026]. doi:10.7326/ANNALS-25-05287 Eva Johnsen, et al. Achieving at Least 15% Weight Loss Within 2 Years of Type 2 Diabetes Diagnosis Is Associated With Lower Risks of Macrovascular and Microvascular Complications: A U.K. Cohort Study. Diabetes Care 20 July 2026; 49 (8): 1480–1489. doi.org/10.2337/dc26-0937 Carel W. le Roux, et al. Survodutide Once Weekly for the Treatment of Adults with Obesity. The New England Journal of Medicine June 2026 DOI: 10.1056/NEJMoa2600751 Yu Wang, Shichao Tang, Xilin Zhou, Ping Zhang. National Trends in Out-of-Pocket Cost for Glucose-Lowering Drugs Among U.S. Adults With Diabetes, 2000–2022. Diabetes Care 20 July 2026; 49 (8): 1414–1419. https://doi.org/10.2337/dc25-2040 Jelle M. Beernink, et al. Effect of Finerenone on Albuminuria in Type 1 Diabetes by Baseline HbA1c Level and Diabetes Duration: An Exploratory Analysis of the FINE-ONE Trial. Diabetes Care 20 July 2026; 49 (8): 1434–1441. https://doi.org/10.2337/dc26-0882 Welch M, Forst T, Jia W et al. Orforglipron compared with dapagliflozin in adults with type 2 diabetes and inadequate glycaemic control with metformin (ACHIEVE-2): a multicentre, randomised, non-inferiority, open-label, phase 3 trial. The Lancet, 2026; 408, 125-140 DOI: 10.1016/S0140-6736(26)00800-7 Presented by: Neil Skolnik, MD, Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, MD, Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Chair-Department of Family Medicine, Abington Jefferson Health DOC Updates is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association's three science and medical journals—Diabetes, Diabetes Care, and Diabetes, Obesity, and CardioMetabolic CARE. Intended for practicing physicians and health care professionals, DOC Updates discusses how the latest research is relevant in clinical practice. For information about the American Diabetes Association's scholarly journals, visit diabetesjournals.org. For more about this podcast, click here.
En este episodio conversamos sobre Ovejas detectives (Glennkill), la ingeniosa y divertida novela de la autora alemana Leonie Swann.Todo empieza en un apacible prado de Irlanda, cuando el pastor George Glenn aparece muerto en la hierba, atravesado por una pala de granja. Sus ovejas, encabezadas por Miss Maple (la más inteligente del rebaño), deciden que no van a quedarse de brazos cruzados esperando a que la policía local haga un trabajo mediocre.A lo largo del episodio comentamos cómo estas peculiares detectives interpretan el comportamiento humano, arman su propia lógica para investigar a los sospechosos del pueblo y se enfrentan a un misterio mucho más complejo de lo que parece a simple vista.Mas información sobre este libro: Las Ovejas Detectives de Leonie SwannSíguenos en nuestras redes sociales
Episode 358! JC is in the host chair with Salvis running the boards, joined by Rita, Preston, Donald, Nora, Veronica, and a bus-riding drop-in from Phil. Stacey is away this week, and the crew opens their hearts for her: Phil asks everyone to keep Stacey James and her family in their prayers as wildfires burn near Spokane, Washington.The retro gold of the night: JC discovers that a developer has ported the legendary DECtalk synthesizer to iOS as a standalone app (GitHub download, Android port too) and plays a live demo. Perfect Paul lives again on a modern iPhone, along with Beautiful Betty, Huge Harry, Frail Frank, Dr. Dennis, Kit the Kid, Uppity Ursula, Rough Rita, and Whispering Wendy. Preston flashes back to Perfect Paul reading the weather radio on his first Sony Walkman. Pure nostalgia for every longtime screen-reader user.Donald unveils Extreme eBook Builder Professional 3.0, his new Windows program for building e-books in Kindle, EPUB, and even standalone EXE formats from any text, Word, RTF, or HTML source. Fully menu-driven and screen-reader friendly with NVDA and JAWS, no mouse required. Retail price $297.KSRN keeps expanding: Preston reports the Crazy Stacey Radio Network got approved on the Audacy app and website just 24 hours before taping, plus new listings on Simple Radio, the radio-browser.info public directory, and MyTunerRadio. He is also registering for the NFB of Pennsylvania state convention in Hershey.In the accessible app corner, JC covers Earshot, a new podcast player app making waves in the blind community, and shares his experience testing Lumen, a voice-driven email app for visually impaired users. Plus the roadmap tease: iOS 27 lands in September, and JC plans a full demo of iOS 27 and the new Siri AI on a future episode. And Suno AI keeps surprising: on this week's NFB Access On podcast, Jonathan Mosen used Suno to build a song about the NFB 2026 convention, and JC shouts out his friend Andrea, who is releasing her own Suno-made songs on Apple Music.Music moments: JC plays a stereo recording from the end of the praise party at his Delight monthly meeting, and Nora's karaoke rendition of "Put on a Happy Face" gets new life with an instrumental track added by a friend she fondly calls "the guru." JC teases a possible duet with Gabby and Jaden next week.Rita shares a belated birthday visit from her cousin, who shares her June 2 birthday and spent his working in Florence. He visited with his wife bearing roses, balloons, and Rita's beloved Nutty Bars. Donald talks tilapia on Dave's Killer Bread with hot sauce, plus a Chili's run for ribs and white cheddar mac and cheese.Echo Grace updates: JC's mom officially became a church member last weekend. New Spanish-team additions Angela Martel, Gabby E., and John Santiago, who now directs the Spanish team. The June Night of Worship recording is up on the Echo Grace YouTube page, honoring Pastor Andrew, who has moved to Florida. The "You Ask For It" sermon series continues, with all messages available as a podcast. Preston also tells the story of the fair: a new country artist named Greyland James, a canceled grandstand headliner, refunded tickets, and a free-stage rescue show of live local country.George is off this week, but Preston refuses to let the tradition die: "Doodles spilled the milk!" - and Donald makes sure George can't have any.Keep technology alive, let your talent shine.Recorded 2026-08-05. Hosted by JC with Salvis on the boards, on the VisionCast Network.
Alexander Aarvold from the University Hospital Southampton joins the show this month to discuss his eagerly anticipated publication on the outcomes of the incomplete acetabuloplasty (or “pelletoplasty”) as an adjunctive treatment during open reduction of developmental hip dislocations. The group also discusses recent publications on treatment of infant femur fractures, open forearm fractures, and the outcomes of periacetabular osteotomy in skeletally immature patients. Your hosts are Carter Clement from Children's Hospital Colorado, Julia Sanders from Children's Hospital Colorado, and Will Morris from Scottish Rite in Dallas. Music by A.A. Aalto. Aarvold A, Uren N, Rhodes A, Elliott KG, Lindisfarne EA, Carsi B, Clarke NMP. Growth Stimulating Minimal Acetabuloplasty, Alongside Hip Open Reduction: A Simpler One-stop Operative Treatment for Developmental Dysplasia of the Hip. J Pediatr Orthop. 2026 Apr 16. doi: 10.1097/BPO.0000000000003259. Epub ahead of print. PMID: 41988894. https://pubmed.ncbi.nlm.nih.gov/41988894/ Murphy-Zane MS, Keeter C, Baumann A. Hip Abduction Brace Is an Effective Treatment Alternative for Femur Fractures in Infants 12 Months and Younger. J Pediatr Orthop. 2026 Jul 1;46(6):e535-e541. doi: 10.1097/BPO.0000000000003172. Epub 2025 Nov 25. PMID: 41490478; PMCID: PMC13232693. https://pubmed.ncbi.nlm.nih.gov/41490478/ Kronk TA, Steiner RP, Ritzman TF, Floccari LV. Surgical Treatment of Pediatric Open Forearm Fractures: A Comparison of Outcomes With or Without Internal Fixation. J Pediatr Orthop. 2026 Jul 1;46(6):e524-e528. doi: 10.1097/BPO.0000000000003159. Epub 2025 Nov 5. PMID: 41191825. https://pubmed.ncbi.nlm.nih.gov/41191825/ Pun SY, Kha ST, Park MO, Richey AE, Pham NS, Millis MB. Is the Bernese Periacetabular Osteotomy Safe for the Treatment of Acetabular Dysplasia When the Triradiate Cartilage is Still Open? A Preliminary Study. J Pediatr Orthop. 2026 Jul 1;46(6):335-341. doi: 10.1097/BPO.0000000000003275. Epub 2026 May 5. PMID: 42084192. https://pubmed.ncbi.nlm.nih.gov/42084192/
Cannabinoid Hyperemesis Syndrome (CHS) continues to be a major clinical challenge in the emergency department. Patients present with severe abdominal pain, intractable vomiting, and significant fluid and electrolyte derangements. CHS often affects people who have been using cannabis routinely for months to years – it can be difficult for patients to understand that their symptoms are related to cannabis. Today, emergency pharmacist Haley Burhans joins us to discuss first-line treatments, fluid management, discharge strategies, and how to navigate these tough bedside conversations. First-Line Therapies: Haldol vs. Droperidol Haloperidol (Haldol): Supported by the HAVOC trial (haloperidol vs. placebo), which showed a reduction in symptoms and ED length of stay. Droperidol: Highly effective alternative with similar dopaminergic mechanism of action. May carry a lower risk of extrapyramidal symptoms compared to haloperidol. Capsaicin Cream: addresses the TRPV1 pathway thought to drive CHS. Patients often dislike it as it causes a burning sensation on the skin and can be inadvertently spread to eyes or face. Can be an option if symptoms persist after trying the above meds and hot showers aren't feasible. Backup Options & Anti-Emetics Alternative Dopaminergic Agents: Metoclopramide or prochlorperazine can be used. Standard Anti-Emetics (e.g., Ondansetron): Serotonergic anti-emetics generally fail to address the underlying CHS pathway. However, a single dose of ondansetron given alongside a butyrophenone (haloperidol/droperidol) is reasonable if you suspect co-existing etiologies. QTc Prolongation Warning: Chronic vomiting leads to electrolyte depletion. Combining anti-emetics and haloperidol or droperidol increases the risk of QTc prolongation. Baseline EKG: Not strictly required for every low-risk patient, but strongly recommended for patients with multiple risk factors (e.g., co-ingestion/use of methadone, history of heart failure, or severe baseline bradycardia). Fluid Resuscitation & Electrolyte Management CHS patients can vomit to the point of severe dehydration and profound electrolyte/acid-base derangements. Fluid Selection: Normal Saline (NS): A solid choice for initial volume resuscitation when sodium and chloride are severely depleted. Lactated Ringer's (LR): Ideal as a follow-up or maintenance fluid because it contains a small amount potassium. Potassium Repletion: Oral repletion may not be tolerated in the acute setting. Consider IV potassium repletion in the ED, followed by oral home supplementation once nausea is controlled. Magnesium: While acute vomiting primarily drives potassium loss, consider IV magnesium if Mg is low or there is concern for QTc prolongation. Discharge Planning: What to Send Home Low-Dose Olanzapine ODT: Send the patient home with 2.5 mg Olanzapine ODT (orally disintegrating tablets). Why it works: It dissolves instantly on the tongue, bypassing the stomach, and provides extended dopaminergic coverage over the multi-day washout period. Pharmacokinetics Pearl: Infrequent user THC half-life: ~1.3 hours (cleared in 5–6 hours). Chronic user THC half-life: THC accumulates in adipose tissue. In heavy users, therapeutic levels can persist for up to 2 weeks, driving prolonged receptor dysregulation even after cessation. Navigating the Bedside Conversation Explaining to a chronic user that their daily cannabis—the very thing they use to relieve nausea—is causing their illness requires empathy and validation. Explain the Neurological Link: Cannabis acts on receptors throughout the entire body, including the brain's nausea center and the nervous system of the gut. Chronic, heavy saturation can paradoxically overload these pathways. Validate Their Experience: Acknowledge how counterintuitive it feels: “I know it's hard to believe that something you've used for years to feel better is causing this, but long-term daily use can change how your body processes it.” Set Realistic Expectations: Reiterate that symptoms will not resolve overnight. Even after stopping, it takes time for the pathways to recalibrate. What do you find most helpful for treating CHS? How do you have these difficult conversaions with your patients? Share your experience with us on social media @empulsepodcast or at ucdavisem.com Hosts: Dr. Julia Magaña, Professor of Pediatric Emergency Medicine at UC Davis Dr. Sarah Medeiros, Professor of Emergency Medicine at UC Davis Guests: Haley Burhans, PharmD, Emergency Medicine Clinical Pharmacist at UC Davis Resources: Borgundvaag B, Bellolio F, Miles I, et al. Guidelines for Reasonable and Appropriate Care in the Emergency Department (GRACE-4): Alcohol use disorder and cannabinoid hyperemesis syndrome management in the emergency department. Acad Emerg Med. 2024 May;31(5):425-455. doi: 10.1111/acem.14911. PMID: 38747203. Rech MA, Shalaby M, Gage KA, Gottlieb M. Managing Cannabinoid Hyperemesis Syndrome. Ann Emerg Med. 2026 Jun;87(6):717-722. doi: 10.1016/j.annemergmed.2025.12.024. Epub 2026 Feb 3. PMID: 41632059. *** Thank you to the UC Davis Department of Emergency Medicine for supporting this podcast and to Orlando Magaña at OM Productions for audio production services.
Send us Fan MailDescription: An immersive reading of Morning Tea by Michael L. Wynn with reflection on atrial fibrillation, strokes, space and time.Website:https://anauscultation.wordpress.comWork: https://www.neurology.org/doi/10.1212/WNL.0000000000214487 References:Wynn ML. Morning Tea. Neurology. 2025 Dec 23;105(12):e214487. doi: 10.1212/WNL.0000000000214487. Epub 2025 Nov 20. PMID: 41264895.
En este episodio exploramos la siniestra y fascinante atmósfera de The House That Horror Built, la aclamada novela gótica moderna de la autora superventas Christina Henry (Good Girls Don't Die, Alice).Conocemos a Harry Adams, una madre soltera y gran aficionada al cine de terror que lucha por salir adelante en Chicago. Cuando consigue trabajo como limpiadora en Bright Horses —la imponente y sombría mansión del afamado (y recluido) director de cine de terror Javier Castillo— parece el empleo soñado. La mansión está repleta de utilería, disfraces escalofriantes y estatuillas de sus películas clásicas.Sin embargo, para mantener el empleo y sostener a su hijo adolescente Gabe, Harry debe seguir la regla principal: discreción absoluta y no hacer preguntas. Pero todo se complica cuando empieza a escuchar susurros y gritos de auxilio tras una puerta siempre cerrada con llave, en una casa donde supuestamente nadie más vive... ¿Son efectos especiales, manifestaciones paranormales o un secreto aterrador que su jefe oculta?
Send us Fan MailIn this small prospective pilot study, Adrianne and Nim explore a domain rarely discussed on rounds, how a mother's cardiovascular function in preeclampsia shapes her newborn's circulatory transition. Using maternal echo and neonatal electrical cardiometry across 13 mother-baby dyads, the authors found an inverse relationship: the worse the mother's cardiac function, the higher the neonate's cardiac output, though vascular tone barely budged. It's a compelling hypothesis about placental strain and fetal adaptation. But Nim pushes back hard on the methodology, pairing this paper with a companion study showing electrical cardiometry consistently overestimates cardiac output in neonates, and questioning why daily echoes were performed on these babies but the results never reported.----Linking maternal and neonatal circulation in preeclampsia. Piani F, Annesi L, Degli Esposti D, Vincenzi S, De Crescenzo S, Della Gatta AN, Simonazzi G, Corvaglia L, Martini S.Am J Physiol Heart Circ Physiol. 2026 Mar 1;330(3):H708-H716. doi: 10.1152/ajpheart.00945.2025. Epub 2026 Jan 12.PMID: 41525138 Free article.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!
Send us Fan MailIn this systematic review and meta-analysis, Nim and Adrianne dig into just how common brain injury really is in neonates with critical congenital heart disease. Pooling 31 studies spanning two decades, the authors found that nearly 70% of these babies show some form of ischemic brain injury, split roughly between pre-operative and post-operative timing. Counter to what most clinicians would predict, kids who went to surgery earlier (days 4-6) had higher rates of white matter injury than those who waited longer. MRI remained the most sensitive tool for picking up these lesions, well ahead of ultrasound or CT. But the data stops well short of proving these findings predict long-term outcomes, and Nim pushes back on the idea that an abnormal scan alone should steer decisions about whether to operate.----Prevalence of Ischemic Brain Injury in Neonates With Congenital Heart Disease: A Systematic Review and Meta-Analysis.Kim C, Chetan D, Kazazian V, Alzamil J, Chau V, Seed M, Miller SP, Selvanathan T.Neurology. 2026 Feb 10;106(3):e214569. doi: 10.1212/WNL.0000000000214569. Epub 2026 Jan 9.PMID: 41512205Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!
Charles Berde, MD, PhD, is the Sara Page Mayo Chair in Pediatric Pain Medicine and a Professor of Anaesthesia at Harvard Medical School. As a co-founder of the Pain Treatment Center at Boston Children's Hospital, he has spent decades at the forefront of pediatric analgesic pharmacology and the development of novel local anesthetics. His extensive translational research focuses on local anesthetic mechanisms and prolonged-duration formulations, making him a preeminent authority on the physiological impacts and safety profiles of these agents in neonates and children. A recipient of the Myron Yaster Lifetime Achievement Award from the Society for Pediatric Anesthesia, Dr. Berde brings unparalleled expertise to the discussion of managing and preventing local anesthetic systemic toxicity (LAST) within the high-stakes environments of the PICU and pediatric operating rooms.Guest Conflicts of Interest (COI)Algavita Bio: Collaborator/Developer of novel, prolonged-duration local anesthetics.Quiver Bioscience: Unpaid Scientific Advisor and co-PI on an NINDS-HEAL grant focused on rare disease pain treatments.Latigo Biotherapeutics: Scientific Advisor and recipient of past research support for novel analgesics development.Algos: Scientific Advisor for non-opioid analgesics development.Learning Objective: By the end of this podcast, listeners should be able to discuss an evidence-based and expert-guided approach to the management of local anesthetic systemic toxicity (LAST) in children.References:Patient and Doctor Reconcile for Greater GoodBerde CB. Toxicity of local anesthetics in infants and children. J Pediatr. 1993 May;122(5 Pt 2):S14-20. doi: 10.1016/s0022-3476(11)80004-1.McMahon K, Paster J, Baker KA. Local anesthetic systemic toxicity in the pediatric patient. Am J Emerg Med. 2022 Apr;54:325.e3-325.e6. doi: 10.1016/j.ajem.2021.10.021. Epub 2021 Oct 25. Lavonas et al. 2023 American Heart Association Focused Update on the Management of Patients With Cardiac Arrest or Life-Threatening Toxicity Due to Poisoning: An Update to the AHA Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2023 Oct 17;148(16):e149-e184. doi: 10.1161/CIR.0000000000001161. Epub 2023 Sep 18. Questions, comments or feedback? Please send us a message at this link (leave email address if you would like us to relpy) Thanks! -Alice & ZacSupport the showHow to support PedsCrit:Please complete our Listener Feedback SurveyPlease rate and review on Spotify and Apple Podcasts!Donations are appreciated @PedsCrit on Venmo , you can also support us by becoming a patron on Patreon. 100% of funds go to supporting the show.Please remember that all content during this episode is intended for educational and entertainment purposes only. It should not be used as medical advice. The views expressed during this episode by hosts and our guests are their own and do not reflect the official position of their institutions. If you have any comments, suggestions, or feedback-you can email us at pedscritpodcast@gmail.com. You can also check out our website at http://www.pedscrit.com. Thank you for listening to this episode of PedsCrit!
En este episodio nos adentramos en el intrigante mundo de "El matrimonio perfecto", la aclamada novela de suspenso psicológico escrita por la autora bestseller Jeneva Rose.Analizamos la historia de Sarah Morgan, una exitosa abogada penalista de Washington D. C. cuya vida parece impecable, hasta que su esposo Adam, un escritor frustrado, es arrestado por el brutal asesinato de su amante, Kelly Summers. Lo verdaderamente inquietante ocurre cuando Sarah toma la impactante decisión de ser la abogada defensora de su propio marido.¿Hasta dónde llega la lealtad? ¿Es Adam culpable o una víctima de una trampa? Desgranamos los giros de guion, el ritmo narrativo y ese final del que todo el mundo está hablando.
Join Jenn Dawson and Mitchell Hanson for some quick-hitting "research hot takes!"Topical Therapies Supporting Links and Articleshttps://nextstepsinderm.com/derm-topics/expanding-the-treatment-landscape-for-atopic-dermatitis-hidradenitis-suppurativa-and-chronic-hand-eczema/https://www.dermatologytimes.com/view/advancing-topical-stewardship-and-expanding-nonsteroidal-optionshttps://www.arcutis.com/arcutis-announces-publication-of-positive-long-term-safety-and-efficacy-data-with-zoryve-roflumilast-cream-0-05-for-treatment-of-mild-to-moderate-atopic-dermatitis-in-children-ages-2-5/Social Unrest Leads to Access Barriers Supporting Links and ArticlesC. L. Presley, J. Meisenheimer VII, C. W. Rundle, S. Maguiness, I. A. Maher, and A. J. M. Anderson, “Social Unrest and Its Implications on the Pediatric Dermatological Patient: Lessons From a Single Center Academic Dermatology Department,” Pediatric Dermatology (2026): 1–2, https://doi.org/10.1111/pde.70260.Mukerjee K, Shah S, Falusi O. State Policies and Access to Care for Immigrant Children—Implications for Pediatric Health Outcomes. JAMA Netw Open. 2025;8(12):e2545833. doi:10.1001/jamanetworkopen.2025.45833Skin of Color in Pediatric Dermatology Supporting Links and ArticlesDondi, A., Ranieri, A., Andreozzi, L., Leuzzi, M., D'Alanno, G., Pierantoni, L., Zama, D., Battelli, E., Calegari, R., Borghesi, A., Lanari, M., & Neri, I. (2026). Skin of Color in Pediatric Dermatology: A Cross-Sectional Retrospective Analysis Addressing Inclusive Diagnosis and Care. Life (Basel, Switzerland), 16(4), 578. https://doi.org/10.3390/life16040578Fagan E, Reagen C, Ituarte B, Shet P, Shaver-Dominguez N, Harter N, Wei EX, Oudenhoven M. Trends in Pediatric Representation Within Skin of Color Dermatology Literature: A Decade-Long Analysis. Pediatr Dermatol. 2026 Jan-Feb;43(1):95-97. doi: 10.1111/pde.16038. Epub 2025 Aug 13. PMID: 41611238.This episode is presented by Disc Medicine. Although Disc Medicine provided funding for this PeDRA Pearls Podcast, the contents of the podcast were developed independently by PeDRA. Learn more about Disc Medicine.
In this episode of *Pediatric Critical Care Insights*, Dr. Monica Gray and Dr. Pradip Kamat chat about how capnography, specifically end-tidal CO2 monitoring, is used in the pediatric ICU. They walk through a real-life case of a 9-year-old with respiratory failure from influenza A, showing how ETCO2 monitoring helps confirm endotracheal tube placement, guides ventilation, spots cardiac arrest, and even helps assess the quality of CPR. Along the way, they break down how to interpret capnography waveforms, discuss different types of devices, and explain the key physiological concepts. The episode is packed with practical, bedside tips for intensivists caring for critically ill kids.Show Highlights:Importance of capnography (end-tidal CO2 monitoring) in the pediatric intensive care unit (PICU)Clinical case study of a 9-year-old boy with respiratory failure due to influenza AUse of capnography for confirming endotracheal tube placement and assessing ventilation statusDetection of cardiac arrest and guidance for CPR quality through ETCO2 monitoringOverview of capnography physics and physiology, including terminology distinctionsTypes of capnography: mainstream vs. sidestream, and their applications in pediatric patientsAssumptions for accurate ETCO2 approximation of arterial CO2 and conditions affecting this relationshipAnalysis of capnography waveform phases and their clinical significancePrognostic value of ETCO2 during cardiac arrest and its correlation with patient outcomesPractical applications of ETCO2 monitoring in critical care, focusing on airway, breathing, and circulation managementReferences:Noninvasive respiratory monitoring and assessment of gas exchange. David F. Butler; Kenneth A. Schenkman. Fuhrman and Zimmerman's Pediatric Critical Care, 43, 483-491.e3Humphreys S, Schibler A, von Ungern-Sternberg BS. Carbon dioxide monitoring in children—A narrative review of physiology, value, and pitfalls in clinical practice. Pediatr Anaesth. 2021;31:839–845. https://doi.org/10.1111/pan.14208Lasa JJ, Dhillon GS, Duff JP, et al. Part 8: Pediatric Advanced Life Support: 2025 American Heart Association and American Academy of Pediatrics Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Pediatrics. 2026;157(1):e2025074351O'Flaherty. Capnography: principles and practice. London: BMJ Publishing Group; 1994.Aminiahidashti H, Shafiee S, Zamani Kiasari A, Sazgar M. Applications of End-Tidal Carbon Dioxide (ETCO2) Monitoring in Emergency Department; a Narrative Review. Emerg (Tehran). 2018;6(1):e5. Epub 2018 Jan 15. PMID: 29503830; PMCID: PMC5827051.
What if one tiny molecule played the central role in your blood pressure, heart health, brain function, exercise performance, and even your risk of diabetes and Alzheimer's disease? Dr Nathan Bryan believes that molecule is nitric oxide. And he walks the walk, having used his N101 products for decades testing shows his endothelial health to be of someone half his biological age! This is an incredible, illuminating podcast that deserves worldwide attention.Dr. Nathan Bryan has been involved in nitric oxide research for the past 25 years and has made many seminal discoveries in the field. His many seminal discoveries have resulted dozens of issued US and International patents and the product technology resulting from his discoveries and inventions has improved patient care worldwide. His companies and product technology are responsible for more than one billion dollars in product sales worldwide. Bryan is an international leader in molecular medicine and nitric oxide biochemistry.Contact: Website - https://n1o1.comJoin us as we explore:The secret power of nitric oxide - the root causes of deficiency, the #1 symptom of insufficiency and why it's molecularly a hormone.Nitric oxide's causation to diabetes, cardiovascular disease and Alzheimer's disease.Eliminating deadly soft arterial plague with nitric oxide lozenges.Why most nitric oxide promoting supplements are false marketing.How your toothpaste and mouth wash are destroying your nitric oxide.How exercise creates nitric oxide.The key enzyme for nitric oxide and how to keep it in high supply.Mentions Podcast - Dr Robert Elliot, https://podcasts.apple.com/za/podcast/the-made-to-thrive-show/id1509452847?i=1000718543359 Podcast - Dr John Osborne, https://podcasts.apple.com/za/podcast/the-made-to-thrive-show/id1509452847?i=1000766332388Study - Elrod JW, Calvert JW, Gundewar S, Bryan NS, Lefer DJ. Nitric oxide promotes distant organ protection: evidence for an endocrine role of nitric oxide. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11430-5. doi: 10.1073/pnas.0800700105. Epub 2008 Aug 6. PMID: 18685092; PMCID: PMC2516252Support the showFollow Steve's socials: Instagram | LinkedIn | YouTube | Facebook | Twitter | TikTokSupport the show on Patreon:As much as we love doing it, there are costs involved and any contribution will allow us to keep going and keep finding the best guests in the world to share their health expertise with you. I'd be grateful and feel so blessed by your support: https://www.patreon.com/MadeToThriveShowSend me a WhatsApp to +27 64 871 0308. Disclaimer: Please see the link for our disclaimer policy for all of our content: https://madetothrive.co.za/terms-and-conditions-and-privacy-policy/
If you've scrolled through your feeds recently, you've probably seen the video that's causing a stir: a prominent infertility doctor sharing her “Hot Take” personal observations on social media, claiming that IUDs are a hidden cause of intrauterine adhesions- or severe uterine scar tissue. Now, Listen. It is completely natural to see a specialist standing in a white coat making a passionate claim and think, "Wow, should I be worried about my birth control?" But here is the reality we need to establish right out of the gate: a handful of individual cases shared online is the very definition of anecdotal evidence. It does not fulfill the criteria of rigorous scientific observation. When we pull back from the algorithm and look at the actual clinical data involving millions of IUD users worldwide, the science shows us something completely different. In fact, large-scale studies demonstrate that IUDs do not cause this scarring—and historically, certain models have actually been used to prevent the uterine walls from sticking together during post-surgical healing. So today, we are separating the scrolling panic from the actual science. We have REA data from the recent FACT (Fertility After Contraceptive Termination) study from 2021 (AJOG). We're breaking down what the data really says, why the internet loves a medical scare, and the true, proven causes of intrauterine adhesions. 1. Abel MK, Wald K, Cedars MI, Noel M. Uterine Synechiae After Intrauterine Device Use: A Case Series. Journal of Assisted Reproduction and Genetics. 2021. 2. Chung E, Wang F, Zhang J, Strug M, Aghajanova L, Lathi R. The impact of prior hormonal intrauterine device (IUD) use on endometrial lining thickness in the fertility clinic setting: a retrospective cohort study. J Assist Reprod Genet. 2026 Jun 25. doi: 10.1007/s10815-026-03950-x. Epub ahead of print. PMID: 42347902.3. Peipert JF, Zhao Q, Schreiber CA, Teal S, Turok DK, Natavio M, Cordon S, Daggy J. Intrauterine device use, sexually transmitted infections, and fertility: a prospective cohort study. Am J Obstet Gynecol. 2021 Aug;225(2):157.e1-157.e9. doi: 10.1016/j.ajog.2021.03.011. Epub 2021 Mar 11. PMID: 33716075.
¿Qué pasa cuando descubres que la persona con la que compartías tu vida era un asesino? ¿Y qué ocurre después, cuando el resto del mundo también lo sabe?En este episodio hablamos de The Secret Lives of Murderers' Wives, de Elizabeth Arnott, un thriller que deja de lado la investigación policial para enfocarse en algo mucho más incómodo: las personas que sobreviven al monstruo.La novela sigue a tres mujeres cuyas vidas quedan destrozadas cuando sus esposos son señalados como asesinos. Aunque cada una enfrenta el escándalo de forma distinta, todas comparten el mismo peso: la culpa por asociación, el juicio público y la eterna pregunta de si realmente conocían al hombre con el que vivían.Elizabeth Arnott construye una historia donde los secretos familiares, las apariencias y las relaciones humanas tienen más protagonismo que la sangre o la violencia. Es un thriller pausado, cargado de tensión psicológica, que poco a poco va revelando que nadie es exactamente quien dice ser.⚠️ Aviso: Este episodio contiene una sección sin spoilers y otra con spoilers, así que podrás decidir hasta dónde escuchar si aún no has leído el libro.Sí. Puedes encontrar la edición Kindle del libro en Amazon aquí:
Antenatal corticosteroids are a MAJOR win in the management of preterm labor. An initial course of antenatal corticosteroids has been shown to reduce morbidity and mortality in patients with preterm prelabor rupture of membranes. For patients who remain undelivered after the initial course of antenatal corticosteroids, it is uncertain whether a booster course of antenatal corticosteroids reduces neonatal morbidity or increases the infection risk. The ACOG, in its current guidance, has concluded that the current evidence is insufficient to make a recommendation. Corticosteroids, especially at the doses given, are also powerful immunosuppressants. When you administer that first course, you accept a minor, calculated risk for a massive, proven benefit. But when you introduce a second course of steroids into a uterine environment that has already been ruptured and exposed to vaginal flora for weeks, you are pouring fuel on the fire. PLUS, the environment for the fetus with prolonged preterm prelabor rupture of membranes is unique. PPPROM, the chronic exposure to ruptured membranes and the resultant oligohydramnios is theorized to trigger a kind of stress response in the fetus- so the baby may make their own endogenous corticosteroid flare. So, rescue steroids after an initial course of steroids in PPROM cases has remained controversial but we have updated data that has provided new insights. In this episode, we will highlight an RCT from 2023 and a more recent systematic review and meta-analysis from May 2026 on this very subject. Listen in for details. 1. Garite TJ, Kurtzman J, Maurel K, Clark R; Obstetrix Collaborative Research Network. Impact of a 'rescue course' of antenatal corticosteroids: a multicenter randomized placebo-controlled trial. Am J Obstet Gynecol. 2009 Mar;200(3):248.e1-9. doi: 10.1016/j.ajog.2009.01.021. Erratum in: Am J Obstet Gynecol. 2009 Oct;201(4):428. PMID: 19254583.2. Tenbrink E, Quain A, Rone V, Harris K, Hadley E, Haas D, Shanks A. Risk of Neonatal Sepsis With Rescue Steroids in Preterm Premature Rupture of Membranes. Cureus. 2023 Apr 6;15(4):e37207. doi: 10.7759/cureus.37207. PMID: 37159785; PMCID: PMC10163895.3. Melamed N, Murphy KE, Pylypjuk C, et al. Timingof Antenatal Corticosteroid Administration and Neonatal Outcomes. JAMA Netw Open. 2025;8(5):e2511315. 4. Porreco R, Garite TJ, Combs CA, Maurel K, Huls CK, Baker S, Fortner KB, Longo SA, Nageotte M, Lewis D, Tran L; Obstetrix Collaborative Research Network. Booster course of antenatal corticosteroids after preterm prelabor rupture of membranes: a double-blind randomized trial. Am J Obstet Gynecol MFM. 2023 May;5(5):100896. doi: 10.1016/j.ajogmf.2023.100896. Epub 2023 Feb 14. PMID: 36796641.5. Da Costa Y, Ramanathan V, Oliveira JA, Brito J, Yousif A. Repeat versus Single Course of Antenatal Corticosteroid in Management of Preterm Premature Rupture of Membranes: A Systematic Review and Meta-analysis. Am J Perinatol. 2026 May;43(7):925-932. doi: 10.1055/a-2708-5314. Epub 2025 Oct 9. PMID: 41067234
The Bakri Postpartum Balloon was described and first used clinically in 1999 by Dr. Younes N. Bakri (Georgia, USA). It is intended to treat postpartum hemorrhage (PPH). In the United States, it received its first major FDA clearance (via 510(k) for commercial marketing) on April 17, 2002. Manufacturer guidelines for the Bakri (Cook Medical) state that the balloon may be left indwelling for a maximum of 24 hours, but the determination of removal time is left to the clinician once “bleeding is controlled and the patient is stable.” However, the optimal duration of intrauterine balloon tamponade placement remains unclear. One retrospective cohort study from AJOG (Einerson et al) of 274 women found no significant difference in PPH outcomes when intrauterine balloon tamponade was left in place for 2–12 hours, compared with more than 12 hours. However, only 30 women had the intrauterine balloon tamponade placement for 10 hours or less. And remember, this was not a prospective trial looking at a minimum of 2 hours, 2 hours was just the lower margin of the “short duration” group. Now, a new RCT (with authors from Denver and Vermont) published in the July 2026 Green Journal provides new data. In this first of its kind pragmatic, randomized trial of noninferiority, a 6-hour duration of intrauterine balloon tamponade usage for postpartum hemorrhage (PPH) control was compared with an 18-hour duration. Listen in for details. 1. Durfee, J., Adkins, K., Heyborne, K., Larrea, N., & Schultz, C. (2026). Intrauterine Balloon Tamponade Duration for Postpartum Hemorrhage: A Randomized Controlled Trial. Obstetrics & Gynecology, 148(1), 113–120. https://doi.org/10.1097/AOG.00000000000062952. Garabedian C, Prats C, Seco A, Deneux-Tharaux C, Rozenberg P, Berveiller P. Duration of Intrauterine Balloon Tamponade in Post-Partum Haemorrhage Management After Vaginal Delivery: A Secondary Cohort Analysis From the French TUB Trial. BJOG. 2026 Jan;133(1):123-131. doi: 10.1111/1471-0528.18345. Epub 2025 Sep 1. PMID: 40888007; PMCID: PMC12676195.3. Einerson BD, Son M, Schneider P, Fields I, Miller ES. The association between intrauterine balloon tamponade duration and postpartum hemorrhage outcomes. Am J Obstet Gynecol 2017;216:300.e1–5.
Join us as we discuss research on mental health and wellbeing in the surgical workforce with Drs. Yang and Collins. The episode explores key findings from recent national surveys showing that nearly one in seven surgeons report suicidal ideation in the past year, with depression, anxiety, and PTSD affecting 15–20% of the surgical population. The conversation highlights protective factors—professional fulfillment, resilience, self-valuation, and connection—while distinguishing between healthy resilience and normalized suffering. Dr. Yang and Dr. Collins discuss systemic barriers including time constraints, out-of-pocket mental health costs, and persistent stigma, alongside actionable institutional interventions: protecting dedicated wellbeing time, establishing peer support and psychological first aid programs, ensuring free mental health access, and expanding research to understand what helps surgeons thrive. The episode emphasizes that self-care is essential to patient safety and invites listeners to become advocates, engage with the literature, and help drive culture change within their institutions. For more information about the AAS wellbeing survey, please email Dr. Yang at CJYANG@MGH.HARVARD.EDU.Host: Steven Thornton, MD (General Surgery Resident at Duke University) Agnes Premkumar (General Surgery Resident at Creighton) Guests: Jeff Yang, MD (Massachusetts General Hospital) Reagan Collins, MD (University of Pennsylvania) Publications Discussed: Hughes TM, Collins RA, Cunningham CE. Depression and Suicide Among American Surgeons-A Grave Threat to the Surgeon Workforce. JAMA Surg. 2024 Jan 1;159(1):7-8. doi: 10.1001/jamasurg.2023.4658. PMID: 37792380. [https://pubmed.ncbi.nlm.nih.gov/37792380/] Collins RA, Herman T, Snyder RA, Haines KL, Stey A, Arora TK, Geevarghese SK, Phillips JD, Vicente D, Griggs CL, McElroy IE, Wall AE, Hughes TM, Sen S, Valinejad J, Alban A, Swan JS, Mercaldo N, Jalali MS, Chhatwal J, Gazelle GS, Rangel E, Yang CJ, Donelan K, Gold JA, West CP, Cunningham C. Unspoken Truths: Mental Health Among Academic Surgeons. Ann Surg. 2024 Mar 1;279(3):429-436. doi: 10.1097/SLA.0000000000006159. Epub 2023 Nov 23. PMID: 37991182. [https://pubmed.ncbi.nlm.nih.gov/37991182/] Yaghmour NA, Bynum WE 4th, Hafferty FW, Könings KD, Richter T, Brigham TP, Nasca TJ. Causes of Death Among US Medical Residents. JAMA Netw Open. 2025 May 1;8(5):e259238. doi: 10.1001/jamanetworkopen.2025.9238. Erratum in: JAMA Netw Open. 2025 Jul 1;8(7):e2523489. doi: 10.1001/jamanetworkopen.2025.23489. PMID: 40366660; PMCID: PMC12079293. [https://pubmed.ncbi.nlm.nih.gov/40366660/] Nasca BJ, Hunt ML, Ramirez RT, Eng JS, Li RD, Agarwal G, Bilimoria KY, Hu YY. One is too many: suicidality among general surgery residents. Acad Med. 2025 Dec 24:wvaf105. doi: 10.1093/acamed/wvaf105. Epub ahead of print. PMID: 41819820. [https://pubmed.ncbi.nlm.nih.gov/41819820/] Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more. If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listenBehind the Knife Premium: https://behindtheknife.org/premiumOral Board Review: https://behindtheknife.org/oral-boardOral Board Simulator: https://behindtheknife.org/oral-board/simulatorGeneral Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-reviewTrauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlasDominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkshipDominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotationVascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-reviewColorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-reviewSurgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-reviewCardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-reviewDownload our App:Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US
Gonadal hormones have a complicated influence on appetite. Estradiol generally suppresses appetite, whereas progesterone opposes estradiol's action such that their combined presence represents a high-risk hormonal milieu for Binge Eating (BE). Testosterone is thought to be associated with increased BE in females but appears protective in males. In some reports, combination oral contraceptive (COC) use has been linked to greater BE-related appetitive processes (e.g., food intake). Now, we have 2 recent, back-to-back publications (June 2026 in JAMA Network Open, and July 2026 in Appetite) that have examined the relationship of hormonal contraception on binge eating behavior. These found seemingly opposing conclusions. Listen in for details. 1. Klump KL, Di Dio AM, Anaya C, et al. Combined Oral Contraceptive Use and Binge Eating. JAMA Netw Open. 2026;9(6):e2619047. doi:10.1001/jamanetworkopen.2026.190472. Katz JM, Yan R, Beltz AM, Gearhardt AN. Associations between reproductive hormonal milieus and binge eating: The roles of sex and hormonal contraceptive use. Appetite. 2026 Jul 1;222:108547. doi: 10.1016/j.appet.2026.108547. Epub 2026 Mar 20. PMID: 41866083.3. Bass L, Prostináková T, Silang KG, Griffiths-Gray A, McQuilliam S, Mahon E, Whitehead A, Johnson KO. Does it hold weight? The perceived effects of contraceptive use on weight status in females: A mixed-methods study. PLoS One. 2025 Dec 29;20(12):e0339323. doi: 10.1371/journal.pone.0339323. PMID: 41460817; PMCID: PMC12747328.