Podcasts about frontline

More than a decade ago, the Emmy-nominated documentary Poor Kids explored poverty in the United States as it's rarely seen: through the eyes of children. Born Poor tells the stories of the same children, now grown, chronicling their lives from childhood to the present day. The 90-minute documentary follows Kaylie, Johnny and Brittany across three chapters of their lives as they grow from kids to teenagers to adults, trying to pursue their dreams while dealing with an economy where they face more obstacles than opportunities — and trying to overcome the grinding poverty that shaped their childhoods.

Dr. Linda Duska and Dr. Kathleen Moore discuss key studies in the evolving controversy over radical upfront surgery versus neoadjuvant chemotherapy in advanced ovarian cancer. TRANSCRIPT Dr. Linda Duska: Hello, and welcome to the ASCO Daily News Podcast. I am your guest host, Dr. Linda Duska. I am a professor of obstetrics and gynecology at the University of Virginia School of Medicine.  On today's episode, we will explore the management of advanced ovarian cancer, specifically with respect to a question that has really stirred some controversy over time, going all the way back more than 20 years: Should we be doing radical upfront surgery in advanced ovarian cancer, or should we be doing neoadjuvant chemotherapy? So, there was a lot of hype about the TRUST study, also called ENGOT ov33/AGO-OVAR OP7, a Phase 3 randomized study that compares upfront surgery with neoadjuvant chemotherapy followed by interval surgery. So, I want to talk about that study today. And joining me for the discussion is Dr. Kathleen Moore, a professor also of obstetrics and gynecology at the University of Oklahoma and the deputy director of the Stephenson Cancer Center, also at the University of Oklahoma Health Sciences.  Dr. Moore, it is so great to be speaking with you today. Thanks for doing this. Dr. Kathleen Moore: Yeah, it's fun to be here. This is going to be fun. Dr. Linda Duska: FYI for our listeners, both of our full disclosures are available in the transcript of this episode.  So let's just jump right in. We already alluded to the fact that the TRUST study addresses a question we have been grappling with in our field. Here's the thing, we have four prior randomized trials on this exact same topic. So, share with me why we needed another one and what maybe was different about this one? Dr. Kathleen Moore: That is, I think, the key question. So we have to level-set kind of our history. Let's start with, why is this even a question? Like, why are we even talking about this today? When we are taking care of a patient with newly diagnosed ovarian cancer, the aim of surgery in advanced ovarian cancer ideally is to prolong a patient's likelihood of disease-free survival, or if you want to use the term "remission," you can use the term "remission." And I think we can all agree that our objective is to improve overall survival in a way that also does not compromise her quality of life through surgical complications, which can have a big effect. The standard for many decades, certainly my entire career, which is now over 20 years, has been to pursue what we call primary cytoreductive surgery, meaning you get a diagnosis and we go right to the operating room with a goal of achieving what we call "no gross residual." That is very different – in the olden days, you would say "optimal" and get down to some predefined small amount of tumor. Now, the goal is you remove everything you can see.  The alternative strategy to that is neoadjuvant chemotherapy followed by interval cytoreductive surgery, and that has been the, quote-unquote, "safer" route because you chemically cytoreduce the cancer, and so, the resulting surgery, I will tell you, is not necessarily easy at all. It can still be very radical surgeries, but they tend to be less radical, less need for bowel resections, splenectomy, radical procedures, and in a short-term look, would be considered safer from a postoperative consideration. Dr. Linda Duska: Well, and also maybe more likely to be successful, right? Because there's less disease, maybe, theoretically. Dr. Kathleen Moore: More likely to be successful in getting to no gross residual. Dr. Linda Duska: Right. Yeah, exactly. Dr. Kathleen Moore: I agree with that. And so, so if the end game, regardless of timing, is you get to no gross residual and you help a patient and there's no difference in overall survival, then it's a no-brainer. We would not be having this conversation. But there remains a question around, while it may be more likely to get to no gross residual, it may be, and I think we can all agree, a less radical, safer surgery, do you lose survival in the long term by this approach? This has become an increasing concern because of the increase in rates of use of neoadjuvant, not only in this country, but abroad. And so, you mentioned the four prior studies. We will not be able to go through them completely. Dr. Linda Duska: Let's talk about the two modern ones, the two from 2020 because neither one of them showed a difference in overall survival, which I think we can agree is, at the end of the day, yes, PFS would be great, but OS is what we're looking for. Dr. Kathleen Moore: OS is definitely what we're looking for. I do think a marked improvement in PFS, like a real prolongation in disease-free survival, for me would be also enough. A modest improvement does not really cut it, but if you are really, really prolonging PFS, you should see that-  Dr. Linda Duska: -manifest in OS. Dr. Kathleen Moore: Yeah, yeah. Okay. So let's talk about the two modern ones. The older ones are EORTC and CHORUS, which I think we've talked about. The two more modern ones are SCORPION and JCOG0602. So, SCORPION was interesting. SCORPION was a very small study, though. So one could say it's underpowered. 170 patients. And they looked at only patients that were incredibly high risk. So, they had to have a Fagotti score, I believe, of over 9, but they were not looking at just low volume disease. Like, those patients were not enrolled in SCORPION. It was patients where you really were questioning, "Should I go to the OR or should I do neoadjuvant? Like, what's the better thing?" It is easy when it's low volume. You're like, "We're going." These were the patients who were like, "Hm, you know, what should I do?" High volume. Patients were young, about 55. The criticism of the older studies, there are many criticisms, but one of them is that, the criticism that is lobbied is that they did not really try. Whatever surgery you got, they did not really try with median operative times of 180 minutes for primary cytoreduction, 120 for neoadjuvant. Like, you and I both know, if you're in a big primary debulking, you're there all day. It's 6 hours. Dr. Linda Duska: Right, and there was no quality control for those studies, either. Dr. Kathleen Moore: No quality control. So, SCORPION, they went 451-minute median for surgery. Like, they really went for it versus four hours and then 253 for the interval, 4 hours. They really went for it on both arms. Complete gross resection was achieved in 50% of the primary cytoreduced. So even though they went for it with these very long surgeries, they only got to the goal half the time. It was almost 80% in the interval group. So they were more successful there. And there was absolutely no difference in PFS or OS. They were right about 15 months PFS, right about 40 months OS.  JCOG0602, of course, done in Japan, a big study, 300 patients, a little bit older population. Surprisingly more stage IV disease in this study than were in SCORPION. SCORPION did not have a lot of stage IV, despite being very bulky tumors. So a third of patients were stage IV. They also had relatively shorter operative times, I would say, 240 minutes for primary, 302 for interval. So still kind of short. Complete gross resection was not achieved very often. 30% of primary cytoreduction. That is not acceptable. Dr. Linda Duska: Well, so let's talk about TRUST. What was different about TRUST? Why was this an important study for us to see? Dr. Kathleen Moore: So the criticism of all of these, and I am not trying to throw shade at anyone, but the criticism of all of these is if you are putting surgery to the test, you are putting the surgeon to the test. And you are assuming that all surgeons are trained equally and are willing to do what it takes to get someone to no gross residual. Dr. Linda Duska: And are in a center that can support the post-op care for those patients. Dr. Kathleen Moore: Which can be ICU care, prolonged time. Absolutely. So when you just open these broadly, you're assuming everyone has the surgical skills and is comfortable doing that and has backup. Everybody has an ICU. Everyone has a blood bank, and you are willing to do that. And that assumption could be wrong. And so what TRUST said is, "Okay, we are only going to open this at centers that have shown they can achieve a certain level of primary cytoreduction to no gross residual disease." And so there was quality criteria. It was based on – it was mostly a European study – so ESGO criteria were used to only allow certified centers to participate. They had to have a surgical volume of over 36 cytoreductive surgeries per year. So you could not be a low volume surgeon. Your complete resection rates that were reported had to be greater than 50% in the upfront setting. I told you on the JCOG, it was 30%. Dr. Linda Duska: Right. So these were the best of the best. This was the best possible surgical situation you could put these patients in, right? Dr. Kathleen Moore: Absolutely. And you support all the things so you could mitigate postoperative complications as well. Dr. Linda Duska: So we are asking the question now again in the ideal situation, right? Dr. Kathleen Moore: Right. Dr. Linda Duska: Which, we can talk about, may or may not be generalizable to real life, but that's a separate issue because we certainly don't have those conditions everywhere where people get cared for with ovarian cancer. But how would you interpret the results of this study? Did it show us anything different? Dr. Kathleen Moore: I am going to say how we should interpret it and then what I am thinking about. It is a negative study. It was designed to show improvement in overall survival in these ideal settings in patients with FIGO stage IIIB and C, they excluded A, these low volume tumors that should absolutely be getting surgery. So FIGO stage IIIB and C and IVA and B that were fit enough to undergo radical surgery randomized to primary cytoreduction or neoadjuvant with interval, and were all given the correct chemo. Dr. Linda Duska: And they were allowed bevacizumab and PARP, also. They could have bevacizumab and PARP. Dr. Kathleen Moore: They were allowed bevacizumab and PARP. Not many of them got PARP, but it was distributed equally, so that would not be a confounder. And so that was important. Overall survival is the endpoint. It was a big study. You know, it was almost 600 patients. So appropriately powered. So let's look at what they reported. When they looked at the patients who were enrolled, this is a large study, almost 600 patients, 345 in the primary cytoreductive arm and 343 in the neoadjuvant arm. Complete resection in these patients was 70% in the primary cytoreductive arm and 85% in the neoadjuvant arm. So in both arms, it was very high. So your selection of site and surgeon worked. You got people to their optimal outcome. So that is very different than any other study that has been reported to date. But what we saw when we looked at overall survival was no statistical difference. The median was, and I know we do not like to talk about medians, but the median in the primary cytoreductive arm was 54 months versus 48 months in the neoadjuvant arm with a hazard ratio of 0.89 and, of course, the confidence interval crossed one. So this is not statistically significant. And that was the primary endpoint. Dr. Linda Duska: I know you are getting to this. They did look at PFS, and that was statistically significant, but to your point about what are we looking for for a reasonable PFS difference? It was about two months difference. When I think about this study, and I know you are coming to this, what I thought was most interesting about this trial, besides the fact that the OS, the primary endpoint was negative, was the subgroup analyses that they did. And, of course, these are hypothesis-generating only. But if you look at, for example, specifically only the stage III group, that group did seem to potentially, again, hypothesis generating, but they did seem to benefit from upfront surgery.  And then one other thing that I want to touch on before we run out of time is, do we think it matters if the patient is BRCA germline positive? Do we think it matters if there is something in particular about that patient from a biomarker standpoint that is different? I am hopeful that more data will be coming out of this study that will help inform this. Of course, unpowered, hypothesis-generating only, but it's just really interesting. What do you think of their subset analysis? Dr. Kathleen Moore: Yeah, I think the subsets are what we are going to be talking about, but we have to emphasize that this was a negative trial as designed. Dr. Linda Duska: Absolutely. Yes. Dr. Kathleen Moore: So we cannot be apologists and be like, "But this or that." It was a negative trial as designed. Now, I am a human and a clinician, and I want what is best for my patients. So I am going to, like, go down the path of subset analyses. So if you look at the stage III tumors that got complete cytoreduction, which was 70% of the cases, your PFS was almost 28 months versus 21.8 months. Dr. Linda Duska: Yes, it becomes more significant. Dr. Kathleen Moore: Yeah, that hazard ratio is 0.69. Again, it is a subset. So even though the P value here is statistically significant, it actually should not have a P value because it is an exploratory analysis. So we have to be very careful. But the hazard ratio is 0.69. So the hypothesis is in this setting, if you're stage III and you go for it and you get someone to no gross residual versus an interval cytoreduction, you could potentially have a 31% reduction in the rate of progression for that patient who got primary cytoreduction. And you see a similar trend in the stage III patients, if you look at overall survival, although the post-progression survival is so long, it's a little bit narrow of a margin.  But I do think there are some nuggets here that, one of our colleagues who is really one of the experts in surgical studies, Dr. Mario Leitao, posted this on X, and I think it really resonated after this because we were all saying, "But what about the subsets?" He is like, "It's a negative study." But at the end of the day, you are going to sit with your patient. The patient should be seen by a GYN oncologist or surgical oncologist with specialty in cytoreduction and a medical oncologist, you know, if that person does not give chemo, and the decision should be made about what to do for that individual patient in that setting. Dr. Linda Duska: Agreed. And along those lines, if you look carefully at their data, the patients who had an upfront cytoreduction had almost twice the risk of having a stoma than the patients who had an interval cytoreduction. And they also had a higher risk of needing to have a bowel resection. The numbers were small, but still, when you look at the surgical complications, as you've already said, they're higher in the upfront group than they are in the interval group. That needs to be taken into account as well when counseling a patient, right? When you have a patient in front of you who says to you, "Dr. Moore, you can take out whatever you want, but whatever you do, don't make me a bag." As long as the patient understands what that means and what they're asking us to do, I think that we need to think about that. Dr. Kathleen Moore: I think that is a great point. And I have definitely seen in our practice, patients who say, "I absolutely would not want an ostomy. It's a nonstarter for me." And we do make different decisions. And you have to just say, "That's the decision we've made," and you kind of move on, and you can't look back and say, "Well, I wish I would have, could have, should have done something else." That is what the patient wants. Ultimately, that patient, her family, autonomous beings, they need to be fully counseled, and you need to counsel that patient as to the site that you are in, her volume of disease, and what you think you can achieve. In my opinion, a patient with stage III cancer who you have the site and the capabilities to get to no gross residual should go to the OR first. That is what I believe. I do not anymore think that for stage IV. I think that this is pretty convincing to me that that is probably a harmful thing. However, I want you to react to this. I think I am going to be a little unpopular in saying this, but for me, one of the biggest take-homes from TRUST was that whether or not, and we can talk about the subsets and the stage III looked better, and I think it did, but both groups did really well. Like, really well. And these were patients with large volume disease. This was not cherry-picked small volume stage IIIs that you could have done an optimal just by doing a hysterectomy. You know, these were patients that needed radical surgery. And both did well. And so what it speaks to me is that anytime you are going to operate on someone with ovary, whether it be frontline, whether it be a primary or interval, you need a high-volume surgeon. That is what I think this means to me. Like, I would want high volume surgeon at a center that could do these surgeries, getting that patient, my family member, me, to no gross residual. That is important. And you and I are both in training centers. I think we ought to take a really strong look at, are we preparing people to do the surgeries that are necessary to get someone to no gross residual 70% and 85% of the time? Dr. Linda Duska: We are going to run out of time, but I want to address that and ask you a provocative question. So, I completely agree with what you said, that surgery is important. But I also think one of the reasons these patients in this study did so well is because all of the incredible new therapies that we have for patients. Because OS is not just about surgery. It is about surgery, but it is also about all of the amazing new therapies we have that you and others have helped us to get through clinical research. And so, how much of that do you think, like, for example, if you look at the PFS and OS rates from CHORUS and EORTC, I get it that they're, that they're not the same. It's different patients, different populations, can't do cross-trial comparisons. But the OS, as you said, in this study was 54 months and 48 months, which is, compared to 2010, we're doing much, much better. It is not just the surgery, it is also all the amazing treatment options we have for these patients, including PARP, including MIRV, including lots of other new therapies. How do you fit that into thinking about all of this? Dr. Kathleen Moore: I do think we are seeing, and we know this just from epidemiologic data that the prevalence of ovarian cancer in many of the countries where the study was done is increasing, despite a decrease in incidence. And why is that? Because people are living longer. Dr. Linda Duska: People are living longer, yeah. Dr. Kathleen Moore: Which is phenomenal. That is what we want. And we do have, I think, better supportive care now. PARP inhibitors in the frontline, which not many of these patients had. Now some of them, this is mainly in Europe, will have gotten them in the first maintenance setting, and I do think that impacts outcome. We do not have that data yet, you know, to kind of see what, I would be really interested to see. We do not do this well because in ovarian cancer, post-progression survival can be so long, we do not do well of tracking what people get when they come off a clinical trial to see how that could impact – you know, how many of them got another surgery? How many of them got a PARP? I think this group probably missed the ADC wave for the most part, because this, mirvetuximab is just very recently available in Europe. Dr. Linda Duska: Unless they were on trial. Dr. Kathleen Moore: Unless they were on trial. But I mean, I think we will have to see. 600 patients, I would bet a lot of them missed the ADC wave. So, I do not know that we can say we know what drove these phenomenal – these are some of the best curves we've seen outside of BRCA. And then coming back to your point about the BRCA population here, that is a really critical question that I do not know that we're ever going to answer. There have been hypotheses around a tumor that is driven by BRCA, if you surgically cytoreduced it, and then chemically cytoreduced it with chemo, and so you're starting PARP with nothing visible and likely still homogeneous clones. Is that the group we cured? And then if you give chemo first before surgery, it allows more rapid development of heterogeneity and more clonal evolution that those are patients who are less likely to be cured, even if they do get cytoreduced to nothing at interval with use of PARP inhibitor in the front line. That is a question that many have brought up as something we would like to understand better. Like, if you are BRCA, should you always just go for it or not? I do not know that we're ever going to really get to that. We are trying to look at some of the other studies and just see if you got neoadjuvant and you had BRCA, was anyone cured? I think that is a question on SOLO1 I would like to know the answer to, and I don't yet, that may help us get to that. But that's sort of something we do think about. You should have a fair number of them in TRUST. It wasn't a stratification factor, as I remember. Dr. Linda Duska: No, it wasn't. They stratified by center, age, and ECOG status Dr. Kathleen Moore: So you would hope with randomization that you would have an equal number in each arm. And they may be able to pull that out and do a very exploratory look. But I would be interested to see just completely hypothesis-generating what this looks like for the patients with BRCA, and I hope that they will present that. I know they're busy at work. They have translational work. They have a lot pending with TRUST. It's an incredibly rich resource that I think is going to teach us a lot, and I am excited to see what they do next. Dr. Linda Duska: So, outside of TRUST, we are out of time. I just want to give you a moment if there were any other messages that you want to share with our listeners before we wrap up. Dr. Kathleen Moore: It's an exciting time to be in GYN oncology. For so long, it was just chemo, and then the PARP inhibitors nudged us along quite a bit. We did move more patients, I believe, to the cure fraction. When we ultimately see OS, I think we'll be able to say that definitively, and that is exciting. But, you know, that is the minority of our patients. And while HRD positive benefits tremendously from PARP, I am not as sure we've moved as many to the cure fraction. Time will tell. But 50% of our patients have these tumors that are less HRD. They have a worse prognosis. I think we can say that and recur more quickly. And so the advent of these antibody-drug conjugates, and we could name 20 of them in development in GYN right now, targeting tumor-associated antigens because we're not really driven by mutations other than BRCA. We do not have a lot of things to come after. We're not lung cancer. We are not breast cancer. But we do have a lot of proteins on the surface of our cancers, and we are finally able to leverage that with some very active regimens. And we're in the early phases, I would say, of really understanding how best to use those, how best to position them, and which one to select for whom in a setting where there is going to be obvious overlap of the targets. So we're going to be really working this problem. It is a good problem. A lot of drugs that work pretty well. How do you individualize for a patient, the patient in front of you with three different markers? How do you optimize it? Where do you put them to really prolong survival? And then we finally have cell surface. We saw at ASCO, CDK2 come into play here for the first time, we've got a cell cycle inhibitor. We've been working on WEE1 and ATR for a long time. CDK2s may hit. Response rates were respectable in a resistant population that was cyclin E overexpressing. We've been working on that biomarker for a long time with a toxicity profile that was surprisingly clean, which I like to see for our patients. So that is a different platform. I think we have got bispecifics on the rise. So there is a pipeline of things behind the ADCs, which is important because we need more than one thing, that makes me feel like in the future, I am probably not going to be using doxil ever for platinum-resistant disease. So, I am going to be excited to retire some of those things. We will say, "Remember when we used to use doxil for platinum-resistant disease?" Dr. Linda Duska: I will be retired by then, but thanks for that thought. Dr. Kathleen Moore: I will remind you. Dr. Linda Duska: You are right. It is such an incredibly exciting time to be taking care of ovarian cancer patients with all the opportunities.  And I want to thank you for sharing your valuable insights with us on this podcast today and for your great work to advance care for patients with GYN cancers. Dr. Kathleen Moore: Likewise. Thanks for having me. Dr. Linda Duska: And thank you to our listeners for your time today. You will find links to the TRUST study and other studies discussed today in the transcript of this episode. Finally, if you value the insights that you hear on the ASCO Daily News Podcast, please take a moment to rate, review, and subscribe wherever you get your podcasts. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. More on today's speakers:   Dr. Linda Duska  @Lduska Dr. Kathleen Moore Follow ASCO on social media:     @ASCO on X (formerly Twitter) ASCO on Bluesky   ASCO on Facebook     ASCO on LinkedIn     Disclosures of Potential Conflicts of Interest:    Dr. Linda Duska:   Consulting or Advisory Role: Regeneron, Inovio Pharmaceuticals, Merck, Ellipses Pharma  Research Funding (Inst.): GlaxoSmithKline, Millenium, Bristol-Myers Squibb, Aeterna Zentaris, Novartis, Abbvie, Tesaro, Cerulean Pharma, Aduro Biotech, Advaxis, Ludwig Institute for Cancer Research, Leap Therapeutics  Patents, Royalties, Other Intellectual Property: UptToDate, Editor, British Journal of Ob/Gyn  Dr. Kathleen Moore: Leadership: GOG Partners, NRG Ovarian Committee Chair Honoraria: Astellas Medivation, Clearity Foundation, IDEOlogy Health, Medscape, Great Debates and Updates, OncLive/MJH Life Sciences, MD Outlook, Curio Science, Plexus, University of Florida, University of Arkansas for Medical Sciences, Congress Chanel, BIOPHARM, CEA/CCO, Physician Education Resource (PER), Research to Practice, Med Learning Group, Peerview, Peerview, PeerVoice, CME Outfitters, Virtual Incision Consulting/Advisory Role: Genentech/Roche, Immunogen, AstraZeneca, Merck, Eisai, Verastem/Pharmacyclics, AADi, Caris Life Sciences, Iovance Biotherapeutics, Janssen Oncology, Regeneron, zentalis, Daiichi Sankyo Europe GmbH, BioNTech SE, Immunocore, Seagen, Takeda Science Foundation, Zymeworks, Profound Bio, ADC Therapeutics, Third Arc, Loxo/Lilly, Bristol Myers Squibb Foundation, Tango Therapeutics, Abbvie, T Knife, F Hoffman La Roche, Tubulis GmbH, Clovis Oncology, Kivu, Genmab/Seagen, Kivu, Genmab/Seagen, Whitehawk, OnCusp Therapeutics, Natera, BeiGene, Karyopharm Therapeutics, Day One Biopharmaceuticals, Debiopharm Group, Foundation Medicine, Novocure Research Funding (Inst.): Mersana, GSK/Tesaro, Duality Biologics, Mersana, GSK/Tesaro, Duality Biologics, Merck, Regeneron, Verasatem, AstraZeneca, Immunogen, Daiichi Sankyo/Lilly, Immunocore, Torl Biotherapeutics, Allarity Therapeutics, IDEAYA Biosciences, Zymeworks, Schrodinger Other Relationship (Inst.): GOG Partners

How do you transform thousands of frontline colleagues from overloaded and under-informed to connected, confident, and AI‑enabled, without breaking the stores?In this episode of The Retail Podcast, Alex sits down with Chris Chandler (Head of Store Support, Midcounties Co‑op) and Mark Williams (Managing Director, WorkJam EMEA) to unpack a full frontline transformation: from paper, WhatsApp groups and scattered comms… to a single digital frontline platform with 90%+ activation and the removal of many tasks removed in just 12 months.

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The IPCA released a scathing review laying out out a chain of senior-level failures around the McSkimming scandal. The question now is whether the public can have any confidence in the police in general and in its leadership. LISTEN ABOVESee omnystudio.com/listener for privacy information.

The 30th COP climate summit is under way in the Brazilian city of Belém. BBC World Service Environment Correspondent Navin Singh Khadka has been covering COP since 2006. He joins us to share his insights on the inner workings of the summit and how it has changed over the years. In 2023, Algeria experienced devastating wildfires, particularly in the Kabylie region which is home to the Amazigh people. The Algerian government typically broadcasts brief updates in Algerian Arabic, which many people in affected regions do not speak. This lack of linguistic inclusivity means that vital information often fails to reach those who need it most. Khadija Maalej from BBC Media Action explains how a project called WISER has set about improving communications in order to save lives. For centuries, people fleeing slavery lived in isolation in Jalapão, in the east of Brazil. They survived by raising cattle and used controlled fires to renew the natural pasture for their herds. Then, in 2001, the government banned burning. The ban had the opposite effect to what was desired: Jalapão began to face gigantic wildfires until, in 2014, the state relented and began to encourage controlled burns again. João Fellet of BBC Brasil has travelled to Jalapão, to speak to the Quilombola people, and watch their controlled burns. This episode of The Documentary comes to you from The Fifth Floor, the show at the heart of global storytelling, with BBC journalists from all around the world. Presented by Faranak Amidi. Produced by Caroline Ferguson and Laura ThomasThis is an EcoAudio certified production. (Photo: Faranak Amidi. Credit: Tricia Yourkevich.)

In this episode, Christian Lane interviews Heather Edward, a seasoned paramedic leader who has transitioned from frontline work to leadership roles and now healthcare philanthropy. Heather discusses her early influences, the challenges of leadership, the importance of mental health, and her current research on paramedic leaders' mental health. She emphasizes the need for open dialogue, self-reflection, and the importance of supportive peer networks in navigating the complexities of leadership in paramedicine.TakeawaysHeather's early family influences shaped her understanding of mental health.Transitioning from frontline work to leadership requires courage and support.Women often need encouragement to step into leadership roles.Disruptive leadership can challenge the status quo for positive change.Self-reflection is crucial for effective leadership.Admitting mistakes is a sign of strong leadership.Conflict in leadership can be navigated with open dialogue.Finding the right environment is essential for personal growth.Leaders often feel alone in their responsibilities.Organizational culture significantly impacts leaders' mental health.Chapters00:00Introduction to Heather Edward01:42Heather's Early Life and Influences03:57Transitioning from Frontline to Leadership06:40The Role of Women in Leadership09:04Disrupting the Status Quo in Leadership11:32Navigating Leadership Challenges15:38The Importance of Self-Reflection17:49Admitting Mistakes as a Leader18:58Dealing with Conflict in Leadership24:26Finding the Right Environment for Growth25:58The Value of Being Uncomfortable28:44Feeling Alone in Leadership30:41Building a Supportive Peer Network32:29Balancing Frontline Responsibilities with Leadership36:54The Impact of Organizational Culture on Mental Health39:21Researching Mental Health in Paramedic Leadership44:34Anticipated Themes from the Research49:32The Future of Paramedic Leadership and Mental Health57:15Conclusion and Next Steps

In this moving conversation, we speak with Alisha, a therapist and Korean adoptee, about her lifelong search for identity and home. She shares the story of being adopted from Korea as an infant, growing up in a small Midwestern town, reuniting with her birth mother in her thirties, and navigating motherhood herself. We explore the myths of adoption, the grief that lives in the body, and what it means to come into community and consciousness as an adult adoptee.You can learn more about Alisha Bennett here. We also recommend this Frontline documentary, “South Korea's Adoption Reckoning.” LOVELINK is hosted by Brooklyn-based therapists Dr. Signe Simon and Dr. Simone Humphrey. If you'd like to contact us directly, send us an email to info@modernmind.co. 

Russia's war with Ukraine is about to enter yet another winter. Meanwhile in the US, Donald Trump is turning his attention to Russia's southern border in an effort to woo the nations of the South Caucasus with diplomacy. What are the US' goals and what does it hope to gain in pulling these nations closer while Russia is distracted in its fight against NATO to the West? Talking Geopolitics host Christian Smith is joined by GPF Chairman George Friedman to make sense of the latest developments. And for more analysis of the region, go to https://geopoliticalfutures.com/gpf-newsletter/ to get access to our free newsletter as well as our NEW special report: Reviving NATO's Eastern Line, by GPF Senior Analyst Antonia Colibasanu. This report is available for a limited time.

The Frontline documentary 'Born Poor' follows kids in three families who try to overcome poverty from childhood through their teen years to young adulthood.

In this episode of the EMS One-Stop podcast, host Rob Lawrence welcomes Dr. Hezedean Smith, who spotlights the human and operational toll of Hurricane Melissa on Jamaica and the wider Caribbean. Dr. Smith draws from first-hand perspective from the ground, detailing catastrophic damage to homes, utilities, roads and communications — which compounded the workload and emotional burden for Jamaica Fire Brigade (JFB) firefighters and EMS providers. Dr. Smith highlighted the Brigade's Amazon Wish List effort, which aims to route essential personal items and operational supplies directly to affected JFB members and stations to sustain continuity of operations and support responders' families. After the break, Dr. Smith switched hats as the newly elected President of NEMSMA to outline the association's renewed momentum: New association management support Expanded member services and credentials The inaugural NEMSMA Leadership Conference The NEMSMA Leadership Conference will take place in Washington, D.C., March 23-24, 2026, intentionally adjacent to EMS on the Hill to create a leadership-plus-advocacy “two-fer.” Highlights include keynote Gen. Robert Neller (Ret.), plus a deep bench of EMS leaders and educators. Memorable quotes from Dr. Hezedean Smith “Many homes destroyed, utility systems interrupted, critical infrastructure in terms of communities having the ability to communicate, leaving thousands displaced, even fire stations having operational challenges as it relates to communication and interoperability ... ” “I stayed in the local fire station. I wanted to be there with the men and women on the ground, to make sure that I had that communication, that constant contact with them.” “My focus will be on the firefighters and ensuring that we get enough supplies to go directly to the firefighters.” “We want to tear down silos. We want to redefine leadership and ensure that we continue to collaborate across this globe.” Additional resources: Jamaica Fire Brigade – Amazon Wish List National EMS Management Association (NEMSMA) NEMSMA Leadership Conference: Washington, D.C., March 23-24, 2026 EMS on the Hill, March 25-26, 2026, Arlington, Virginia International Journal of Paramedicine EMS One-Stop: General Robert Neller on ethical leadership and adaptability Episode timeline: 00:46 – Quick industry/policy update 01:27 – Set-up: Hurricane Melissa overview; impact stats and current situation 02:12 – Welcome Dr. Hezedean Smith 02:26 – Dr. Smith's backstory: Jamaica roots, USAF medic, Orlando FD, two fire chief roles, GES Consulting, Caribbean EMS focus 04:20 – First reactions to Melissa: scale of damage; compounded human toll 05:58 – Deployment cadence: aligning with JFB command, CDEMA, national EOC; travel hurdles; rapid integration on arrival 08:28 – Why existing relationships matter; staying in-station with crews; supporting leaders and frontline needs 11:13 – Call to action: Amazon wish list for responders' personal and operational needs; distribution via JFB logistics 13:20 – Specific needs (PPE, boots, clothing, hygiene, basic medical supplies) and the ongoing recovery realities 17:46 – NEMSMA — new president, renewed energy, new AMC, who NEMSMA serves 20:14 – Board/leadership shout-outs; programs (FTEP, ACPE), member services, momentum 22:49 – Conference preview (Mar 23–24, 2026, D.C.): theme — disruptive leadership; Gen. Robert Neller keynote; speaker lineup; proximity to EMS on the Hill 26:29 – IJOP collaboration and research-to-podcast pipeline; communications and sponsorship improvements 28:29 – Closing thanks; unified call to support JFB and engage with NEMSMA initiatives Rate and review the EMS One-Stop podcast Enjoying the show? Please take a moment to rate and review us on Apple Podcasts. Contact the EMS One-Stop team at editor@EMS1.com to share ideas, suggestions and feedback. Listen on Apple Podcasts, Amazon Music, Spotify and RSS feed.

A Nash Holos Feature Interview with Nick Buderatsky, a patriotic Ukrainian volunteer who was mentored by legendary combat medic Taira and went on to become a civilian paramedic working on Ukraine's front lines, including Avdiivka and Irpin. Despite being injured himself, he helped save countless lives — including in Bucha and Irpin, where he set up a mobile field hospital modeled after a M.A.S.H. unit (Mobile Army Surgical Hospital) following the 2022 massacre.He also is an IT specialist and helped Ukrainian soldiers innovate and improvise when western support lagged. I met Nick back in 2015 when he took me to visit a Donetsk airport Cyborg in a military hospital in Kyiv. (Story here) Originally aired in February, 2024.Disclaimer: References to “M.A.S.H.” are used in a descriptive, non-branded context to denote mobile surgical field hospitals. This podcast is not affiliated with or endorsed by the MAS*H television series or its rights holders. Hosted on Acast. See acast.com/privacy for more information.

Today on The Clive Holland Show, we're getting real about the toughest jobs in the trade world.We all have that one project that went completely sideways! Maybe it was a nightmare client, missing materials, unpredictable weather, or just a day from hell. Today we heard your stories: What was the worst job you've done this year, and how did you turn it around?Join Clive as he talks with tradespeople about resilience, problem-solving, and keeping your cool when the job gets tough. Share your experiences, laugh, commiserate, and learn from the highs and lows of life on site.Catch Clive On Fix Radio Monday - Thursday 12 PM - 3 PM Across The UK On DAB Radio And Online At https://www.fixradio.co.uk/ 

Fr. Dom is back! James and Fr. Dom tackle one of the most misunderstood yet absolutely essential topics in the spiritual life: baptism. This is not just another Church formality. This is the dividing line between belonging to the Kingdom of God and the dominion of Satan.Drawing from Scripture, the Catechism, and the wisdom of the saints, TMC lays out with clarity and conviction what baptism truly does: freeing us from original sin, making us sons of God, and incorporating us into the Body of Christ. Without it, you remain enslaved to sin and outside the family of God.You'll hear why the early Church Fathers, councils, and even the Protestant revolution itself reveal that there's no salvation without baptism. Fr. Dominic doesn't sugarcoat the truth — he calls modern men to wake up to the spiritual reality of this sacrament and to recognize the Church as the one true means of salvation given to us by Christ Himself.James and Fr. Dom also confront why our age resists authority, why relativism and pride have blinded so many, and why men must reclaim their God-given duty to lead their families into the faith by baptizing their children without hesitation.In this episode, you'll discover:The biblical foundation of baptism — from Acts to Corinthians to the Great Commission.Why baptism isn't symbolic but supernatural warfare.How baptism undoes the curse of Adam and Eve and reclaims your soul for God.Why relativism, pride, and modernism are destroying moral order — and what Catholic men must do to restore it.The spiritual danger of delaying baptism for your children.Why contemplating death (memento mori) prepares your soul for heaven.Challenge to Men: If you have children who aren't baptized — schedule it now. Don't delay. Fathers, you are the protectors of your family's souls. Take your post. Lead your household back under the protection of God. Baptism is the first weapon in your family's arsenal against hell.3 Powerful Quotes:“Through baptism, we are freed from sin and reborn as sons of God. We become members of Christ and sharers in His mission.”“If you're not going to follow God, then who do you belong to? Baptism begins to undo definitively the faults of our first parents in the garden.”“Parents, you're supposed to protect your child. Why would you let them walk this world owned by Satan when baptism can claim them for God?”Key Takeaway: Baptism isn't optional — it's the decisive act that transfers your soul from the dominion of darkness to the Kingdom of Christ. Every Catholic man must treat it as a matter of eternal life and death.Send us a text Support the showPlease prayerfully consider supporting the podcast on our Buy Me A Coffee page. to help grow the show to reach as many men as possible! Thank you for your prayers and support. Be sure to follow us on X for more great content. As always, please pray for us! We are men who strive daily to be holy, to become saints and we cannot do that without the help of the Holy Ghost! Subscribe to our YouTube page to see our manly and holy faces Check out our website Contact us at themanlycatholic@gmail.com

AP correspondent Charles de Ledesma reports on the latest Russia attacks in Ukraine.

From Kidnap Zones to Kiosks: Lessons in Leadership, Risk and Resilience Derek welcomes Richard Goodworth, an experienced Chief Financial Officer (ACCA) whose career has spanned the trading floors of London, the luxury world of Molton Brown, the high-risk security operations of Control Risks, - and now, the cutting-edge world of ImageHolders — creators of innovative self-service kiosks used by the NHS, United Airlines, Nordstrom, Hard Rock Café, and Mercedes-Benz.If you've ever tapped your details into a digital kiosk at McDonald's, checked in at an airport, or dropped a parcel at the Post Office — chances are, you've used one of Richard's creations!

In this episode, Martin spoke to the authors of two compelling posters showcased at the 2025 Infection Prevention Society Conference in Brighton, each discussing practical, data-driven approaches to reducing avoidable harm. Download the posters and have a listen to two authors with a passion for their projects. First, Catherine Lemsalu, a Dental Nurse from the IPC Team at University Hospital Plymouth discusses her quality-improvement work on an acute stroke ward, demonstrating how structured mouth-care assessment, targeted staff education, and consistent daily oral care contributed to reductions in non-ventilated hospital-acquired pneumonia and Clostridioides difficile infections. Her poster highlights how simple, early interventions—done well—can strengthen antimicrobial stewardship, improve patient outcomes, and build ward-level capability through mouth-care champions. We then explored the development of a national surveillance framework and digital tool for vascular access device–related bloodstream infections (VAD-BSI) with Sue Rowlands from The Royal Wolverhampton NHS Trust. Their multidisciplinary initiative has created a standardised, user-friendly approach to classifying VAD-BSI, identifying risk factors, and generating automated visual outputs that support local reporting, audit, and education. Early pilot data show strong usability, enhanced insight into bloodstream infection epidemiology, and meaningful impact on line-care practice. Posters can be downloaded here: Reduction of hospital-acquired pneumonia and Clostridioides difficile infections through focused line care Developing a surveillance framework and digital tool for Vascular Access Device-Related Bloodstream Infections (VAD-BSI): improving patient safety through local data and national insight

In this episode, Martin spoke to the authors of two compelling posters showcased at the 2025 Infection Prevention Society Conference in Brighton, each discussing practical, data-driven approaches to reducing avoidable harm. Download the posters and have a listen to two authors with a passion for their projects. First, Catherine Lemsalu, a Dental Nurse from the IPC Team at University Hospital Plymouth discusses her quality-improvement work on an acute stroke ward, demonstrating how structured mouth-care assessment, targeted staff education, and consistent daily oral care contributed to reductions in non-ventilated hospital-acquired pneumonia and Clostridioides difficile infections. Her poster highlights how simple, early interventions—done well—can strengthen antimicrobial stewardship, improve patient outcomes, and build ward-level capability through mouth-care champions. We then explored the development of a national surveillance framework and digital tool for vascular access device–related bloodstream infections (VAD-BSI) with Sue Rowlands from The Royal Wolverhampton NHS Trust. Their multidisciplinary initiative has created a standardised, user-friendly approach to classifying VAD-BSI, identifying risk factors, and generating automated visual outputs that support local reporting, audit, and education. Early pilot data show strong usability, enhanced insight into bloodstream infection epidemiology, and meaningful impact on line-care practice. Posters can be downloaded here: Reduction of hospital-acquired pneumonia and Clostridioides difficile infections through focused line care Developing a surveillance framework and digital tool for Vascular Access Device-Related Bloodstream Infections (VAD-BSI): improving patient safety through local data and national insight

Day 1,357.Today, the battle for Pokrovsk continues to rage on with 300 Russian soldiers now in the city, pressing forward to the north. We discuss the corruption probe in Ukraine targeting one of Zelensky's close allies and how it led to the president's debacle over the summer when he tried to curtail Ukraine's two anti-corruption agencies. Finally, we zoom in on Lavrov's disappearance from the public eye in the last couple of weeks and on the patterns of drone incursions across Europe these past two months. ContributorsAdélie Pojzman-Pontay (Journalist and Producer). @adeliepjz on X.Memphis Barker (Senior Foreign Correspondent). @memphisbarker on X.Roland Oliphant (Chief Foreign Analyst). @RolandOliphant on X.Joe Barnes (Brussels Correspondent). @Barnes_Joe on X.SIGN UP TO THE ‘UKRAINE: THE LATEST' WEEKLY NEWSLETTER:http://telegraph.co.uk/ukrainenewsletter Each week, Dom Nicholls and Francis Dearnley answer your questions, provide recommended reading, and give exclusive analysis and behind-the-scenes insights – plus maps of the frontlines and diagrams of weapons to complement our daily reporting. It's free for everyone, including non-subscribers.CONTENT REFERENCED:‘We are losing Pokrovsk': Russia nears biggest gain since 2023, The Telegraphhttps://www.telegraph.co.uk/world-news/2025/11/11/pokrovsk-ukraine-russia-gain-volodymyr-zelensky-gen-syrskyi/Who is Timur Mindich, Zelensky's secretive associate at the center of a major corruption probe?, Kyiv Independenthttps://kyivindependent.com/who-is-timur-mindich/?mc_cid=721276d3ca&mc_eid=4a5b852913Where's Sergei Lavrov? Rumours swirl over the fate of Putin's foreign affairs enforcer, The Telegraphhttps://www.telegraph.co.uk/politics/2025/11/10/the-rumours-swirling-over-the-fate-of-sergei-lavrov/Mapped: Russia's new drone war against Europe, The Telegraphhttps://www.telegraph.co.uk/world-news/2025/11/11/mapped-russia-new-drone-war-against-europe/Poppies and cornflowers became symbols of November 11 thanks to women forgotten by history, Le Mondehttps://www.lemonde.fr/en/m-le-mag/article/2025/11/11/poppies-and-cornflowers-became-symbols-of-november-11-thanks-to-women-forgotten-by-history_6747339_117.htmlThe Poppy Lady, The Story of Madame Anna Guérin and the Remembrance Poppyhttps://www.pen-and-sword.co.uk/The-Poppy-Lady-Hardback/p/21829Subscribe: telegraph.co.uk/ukrainethelatestEmail: ukrainepod@telegraph.co.uk Hosted on Acast. See acast.com/privacy for more information.

Community banks have always excelled at building relationships. But in a market driven by data, relationships alone aren't enough. The next wave of growth in banking depends on turning customer insights into action. This means empowering marketing, sales, and frontline teams to collaborate smarter and deliver more personalized experiences.In this episode of the Banking on Data Podcast, Edward Vincent, CEO of Lumio, sits down with Josh Barclay, Director of Growth Marketing at BusinessNext and host of the Banking on Experience podcast, to discuss how modern community financial institutions can use actionable data to align teams, break down silos, and drive meaningful growth. Their conversation explores how banks can empower their frontline with real-time, context-rich insights, why data quality and accessibility matter more than volume, and what the future of data-driven sales enablement looks like in community banking.Follow us to stay in the know!

出演：永井玲衣さん（哲学者） 2025年11月11日（火）「FrontLine Session」より。 発信型ニュース・プロジェクト「荻上チキ・Session」 ★月～金曜日　17:00～20:00　TBSラジオで生放送 パーソナリティ：荻上チキ、西川あやの（代演） 番組HP：⁠⁠⁠⁠⁠⁠荻上チキ・Session⁠⁠⁠⁠⁠⁠ 番組メールアドレス：⁠⁠⁠⁠⁠⁠ss954@tbs.co.jp⁠⁠⁠⁠⁠⁠ 番組Xアカウント：⁠⁠⁠⁠⁠⁠@Session_1530⁠⁠⁠⁠⁠⁠ ハッシュタグは ⁠⁠⁠⁠⁠⁠#ss954 Learn more about your ad choices. Visit megaphone.fm/adchoices

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ゲスト：金井真紀さん（文筆家・イラストレーター） 2025年11月10日（月）「FrontLine Session」より 発信型ニュース・プロジェクト「荻上チキ・Session」 ★月～金曜日　17:00～20:00　TBSラジオで生放送 パーソナリティ：荻上チキ、南部広美 番組HP：⁠荻上チキ・Session⁠ 番組メールアドレス：⁠ss954@tbs.co.jp⁠ 番組Xアカウント：⁠@Session_1530⁠ ハッシュタグは ⁠#ss954 Learn more about your ad choices. Visit megaphone.fm/adchoices

Would you like our assistance in co-designing a customised program, beginning with a maturity assessment and leadership coaching, to ensure that your safety and operational excellence initiatives support each other effectively? Contact usSummary KeywordsSafety excellence, Safety culture, Bradley Curve, DSS+, Simon Flack, Enterprise Excellence Podcast, Operational excellence, Zero harm, Safety leadership, Visible felt leadership, Risk tolerance, Safety huddles, Near miss reporting, Root cause problem solving, Lean leadership, Frontline engagement, Safety management systems, DuPont safety, Continuous improvement, Workplace safety In this episode of the Enterprise Excellence Podcast, Brad Jeavons is joined again by Simon Flack from DSS+, returning after his earlier appearance on Visual Workplace and Systems. This time, Simon dives deep into Safety Excellence—why he moved from operational excellence into safety, and how a very personal childhood experience shaped his purpose.Simon explains the Bradley Curve and the four stages of safety culture maturity—from reactive to dependent, then independent and ultimately interdependent—emphasising the critical shift from compliance (“I do it because I have to”) to commitment (“I do it because it's the right thing to do for me and my family”). He explores how organisations can truly understand their current culture, challenge their tolerance to risk, and avoid relying on “dumb luck” to get people home safe.Brad and Simon unpack practical levers: meaningful safety huddles, sharing near-miss stories, and leaders being visible, felt leaders who show care, curiosity and humility. They discuss the importance of frontline ownership, leading measures, and root-cause problem solving on the biggest risks. Simon also shares how DSS+ co-designs tailored journeys with clients, linking safety excellence to operational excellence, productivity and long-term sustainability. At the heart of it all is one simple aim: every parent, partner, and friend comes home at least as well as they left for work.  Key takeaways ·       All injuries can be prevented – safety excellence starts with the belief that zero harm is achievable, not aspirational.·       The Bradley Curve matters – knowing whether your culture is reactive, dependent, independent or interdependent shapes your improvement pathway.·       Risk tolerance grows quietly – repeated “micro wins” from risky shortcuts raise tolerance until something goes wrong; near-miss sharing helps reset it.·       Leaders must be “visible, felt leaders” – showing up with care, curiosity, and humility builds trust and genuine safety ownership.·       Safety excellence = operational excellence – as safety culture matures, incidents fall and productivity, quality and engagement rise together. What's next?1.     If you need support, consider co-designing a tailored program with us, starting with a maturity assessment and leadership coaching – so that your safety and operational excellence journeys reinforce each other.2.     Join our next community meeting.  https://www.enterpriseexcellenceacademy.com/community.3.     Listen to another podcast with Simon Flack, https://podcasts.apple.com/us/podcast/139-simon-flack-visual-management-and-enterprise/id1528932427?i=1000614895810To learn more about what we do, visit https://enterpriseexcellencegroup.com.au/Thanks for your time, and thanks for helping to create a better future.

Episode Summary: Marine veteran Andrew Bain spent the past 20 years living and working in Ukraine. He and Adm. Ihor Voronchenko (Ret), former commander of the Ukrainian Navy, join hosts Heather "Lucky" Penney and Lt. Gen. David Deptula, USAF (Ret.) for an inside look at technical and tactical innovation in the fight for survival against Russian aggression. Credits: Host: Heather "Lucky" Penney, Director of Research, The Mitchell Institute for Aerospace Studies Producer: Shane Thin  Executive Producer: Douglas Birkey Guest: Lt Gen David A. Deptula, USAF (Ret.), Dean, The Mitchell Institute for Aerospace Studies Guest: Adm. Ihor Voronchenko, Ukrainian Navy (Ret.) Guest: Andrew K. Bain, Executive Director and Member, Board of Directors, Ukrainian Freedom Fund Language Interpreter: Olha Paniuk Links: Subscribe to our Youtube Channel: https://bit.ly/3GbA5Of Website: https://mitchellaerospacepower.org/ Twitter: https://twitter.com/MitchellStudies Facebook: https://www.facebook.com/Mitchell.Institute.Aerospace LinkedIn: https://bit.ly/3nzBisb Instagram: https://www.instagram.com/mitchellstudies/ #MitchellStudies #AerospaceAdvantage #Ukraine #Europe #Russia

Liberal senator Sarah Henderson has refused to endorse opposition leader Sussan Ley, saying she is “losing support” amid falling polls and party infighting over climate policy; This year is on track to be the second or third warmest on record; Hollywood actor Angelina Jolie visited one of Ukraine’s most dangerous frontline cities; Carrie Bickmore has been named Victoria’s 2026 Australian of the Year. Support independent women's media CREDITS Host/Producer: Tahli Blackman Audio Production: Lu HillBecome a Mamamia subscriber: https://www.mamamia.com.au/subscribeSee omnystudio.com/listener for privacy information.

ゲスト：柳樂光隆さん（音楽評論家、DJ） 2025年11月6日（木）「FrontLine Session」より ※楽曲は流れませんのでご了承ください。 ========================================= 発信型ニュース・プロジェクト「荻上チキ・Session」 ★月～金曜日　17:00～20:00　TBSラジオで生放送 パーソナリティ：荻上チキ、南部広美 番組HP：⁠⁠⁠⁠⁠⁠荻上チキ・Session⁠⁠⁠⁠⁠⁠ 番組メールアドレス：⁠⁠⁠⁠⁠⁠ss954@tbs.co.jp⁠⁠⁠⁠⁠⁠ 番組Xアカウント：⁠⁠⁠⁠⁠⁠@Session_1530⁠⁠⁠⁠⁠⁠ ハッシュタグは ⁠⁠⁠⁠⁠⁠#ss954 Learn more about your ad choices. Visit megaphone.fm/adchoices

Day 1,351.Today, as reports from Pokrovsk indicate Russian troops now hold positions across nearly the entire city, prosecutors in Kharkiv launch a new war crimes investigation after footage emerged of an alleged Russian FPV drone strike on two civilians carrying a white flag near Kharkiv. We also examine today's Joint Expeditionary Force meeting in Norway – asking whether it's wise for the group to brand itself as “NATO's first responders” – before doing a deep dive into recent cases of Ukrainian and Russian spycraft. Later, we speak with the commander of a Ukrainian drone unit who helped destroy Russian forces following the so-called “breakthrough” in Dobropillya.ContributorsDominic Nicholls (Associate Editor of Defence). @DomNicholls on X.Francis Dearnley (Executive Editor for Audio). @FrancisDearnley on X.With thanks to Dimko Zhluktenko.SIGN UP TO THE ‘UKRAINE: THE LATEST' WEEKLY NEWSLETTER:http://telegraph.co.uk/ukrainenewsletter Each week, Dom Nicholls and Francis Dearnley answer your questions, provide recommended reading, and give exclusive analysis and behind-the-scenes insights – plus maps of the frontlines and diagrams of weapons to complement our daily reporting. It's free for everyone, including non-subscribers.CONTENT REFERENCED:Learn more about Dimko's charity, Dzyga's Paw:https://dzygaspaw.com/ Dom's story on MI5 chief's warnings (The Telegraph):https://www.telegraph.co.uk/news/2025/10/16/sir-ken-mccallum-mi5-china-spy-scandal-national-security/ The Ukrainian double-agent playing Russia at its own game (The Telegraph):https://www.telegraph.co.uk/world-news/2025/11/01/ukraine-russia-war-double-agent-security-services/ A champion like no other: The curious life of a Unit 29155 operative (The Insider):https://theins.ru/en/inv/286477 Russia moves to year-round conscription from 2026 (Kyiv Independent):https://kyivindependent.com/putin-signs-law-allowing-year-round-conscription-in-russia/?mc_cid=fb29c7d440&mc_eid=08d0680a95 Is there a risk of encirclement in Pokrovsk and what awaits Myrnohrad? Soldiers explain (Hromadske):https://hromadske.ua/en/war/254005-ti-khto-v-pokrovsku-na-peredovykh-pozytsiiakh-vze-v-pryntsypi-v-otochenni-z-iakoho-malo-shansiv-vyyty Subscribe: telegraph.co.uk/ukrainethelatestEmail: ukrainepod@telegraph.co.uk Hosted on Acast. See acast.com/privacy for more information.

What happens when experienced B2B sales professionals—many with engineering backgrounds—spend six months mastering consultative selling techniques? In this episode, I share the five most impactful lessons from a recent training program with high-end hydraulic and timing solutions salespeople.You'll discover why being mindful of the "okay vs. not okay" dynamic transforms customer interactions, how upfront agreements and detachment create better outcomes, and the critical importance of operating on two levels simultaneously—being in the conversation while also observing it.Whether you're selling complex solutions or leading a sales team, these field-tested insights will help you connect more authentically with prospects and close more deals.12 Bold Moves - Audiobook: Want to break free and soar to new heights? "12 Bold Moves" the Audiobook, is your gateway to a fearless reinvention of self and unlocking unprecedented sales success. Get your FREE copy now at http://12boldmoves.com/audiobook.Have a question for Bill or a topic you'd like him to discuss in a future episode? Email him at listener@caskeytraining.com.Schedule a Call: If you'd like to learn more about how Bill can help you or your team reach your potential, schedule a call at http://scheduleacallwithcaskey.com.

Running an EMS operation on a large scale demands great responsibilities—for both the community you serve as well as the personnel that deliver that service. Mike McCabe sits down with David Basnak, president and executive director of EmergyCare, the largest EMS and medical transport provider in northwest Pennsylvania, to learn more about his priorities in the areas of career development, quality improvement, staff safety and state-of-the-art equipment. Sponsored by Medix Specialty Vehicles.

In this episode, Katie welcomes back the Internal Comms Podcast's MVP, founder and CEO of Dewpoint Communications Victoria Dew. Back in 2022, Victoria featured on episode 61 of the podcast – our most popular yet, with 21,000 listens and counting. She returns three years later with the same incredible insights into our industry, an infectious enthusiasm for all things IC and a clear-minded view of our, at times, convoluted profession. She also comes clutching her fascinating new report and, in this episode, Victoria and Katie discuss Connecting the frontline: Current trends, challenges, and strategic opportunities in workforce communication at length. It's a report that addresses the successes and failures of organisations communicating with the 80% of workers who aren't tied to a desk. And, as Victoria explains, it's a ‘love letter to comms pros'. They explore ‘cracking the frontline code', the misconception that frontline workers aren't particularly engaged, the AI-influenced changes coming down the line and a business-focused way of thinking about your comms function. Tune in, enjoy and join the conversation – #TheICPodcast

Sophia Yanchevska is a nineteen-year-old combat medic working on the frontline in Ukraine. She has been speaking to Lucy about seeing the war close up, the friends she has lost, and her hopes for the future. Plus, what it was like to feature in a new film ‘She' directed by Evgen Matvienko which recently premiered in London.Also this week - Victoria, Vitaly, and Lucy discuss the situation in Pokrovsk, the city Russia has been attempting to seize for more than a year, as it looks to strengthen its foothold in the Donetsk region.Today's episode is presented by Victoria Derbyshire, Vitaly Shevchenko and Lucy Hockings. The producers were Laurie Kalus and Julia Webster. The technical producer was Ben Andrews. The social producer was Gabriel Purcell-Davis. The series producer is Chris Flynn. The senior news editor is Sam Bonham. Email Ukrainecast@bbc.co.uk with your questions and comments. You can also send us a message or voice note via WhatsApp, Signal or Telegram to +44 330 1239480You can join the Ukrainecast discussion on Newscast's Discord server here: tinyurl.com/ukrainecastdiscord

In this episode of Transform Your Workplace, host Brandon Laws welcomes back Victoria Dew, founder and CEO of Dewpoint Communications, to unpack findings from her latest research report, Connecting the Frontline: Current Trends, Challenges, and Strategic Opportunities in Workforce Communication. Victoria shares what her team discovered after interviewing communication leaders across 18 industries — from manufacturing and healthcare to construction and education — about the urgent need to better connect with deskless and frontline workers. Together, Brandon and Victoria discuss how to bridge the gap between corporate and hourly employees, why 72% of frontline workers don't understand company strategy, and how leaders can close that gap through listening, technology, and culture change. You'll also hear insights on AI's role in communication, manager overload, the importance of in-person connection, and how organizations can transform frontline workers into powerful brand ambassadors. If you lead people, especially those on the frontlines, this conversation will help you reimagine how communication, connection, and culture can drive performance across your entire organization. Key Timestamps: [00:00] Introduction — Purpose of the show and Xenium's Custom HR solutions [01:00] Meet Victoria Dew — Founder and CEO of Dewpoint Communications [02:00] Inside the new report Connecting the Frontline and its goals [04:00] Why frontline workers are often "out of sight, out of mind" [05:00] The shifting meaning of work for frontline employees [07:00] Understanding the "Ferrari vs. horse and carriage" gap between workers [09:00] Why 72% of frontline employees don't understand company strategy [11:00] Creating context and meaning through internal communication [12:00] Supporting overburdened managers as key communication channels [14:00] Moving beyond one-way communication to real feedback loops [16:00] Listening circles, pulse checks, and two-way engagement [18:00] Bridging the tech divide for frontline communication [19:00] AI as a game changer for communication teams [22:00] Why face-to-face connection still matters [23:00] Empowering frontline workers as brand ambassadors [25:00] Shifting the digital divide from "too hard" to "must have" [27:00] Culture change and adoption challenges in communication tech [29:00] How data drives — but doesn't replace — emotional change [30:00] The evolving role of communication professionals in the AI era [31:00] Practical steps leaders can take to connect with the frontline [33:00] Where to find and download Victoria's full report A QUICK GLIMPSE INTO OUR PODCAST Podcast: Transform Your Workplace, sponsored by Xenium HR Host: Brandon Laws In Brandon's own words: "The Transform Your Workplace podcast is your go-to source for the latest workplace trends, big ideas, and time-tested methods straight from the mouths of industry experts and respected thought leaders." About Xenium HR Xenium HR is on a mission to transform workplaces by providing expert outsourced HR and payroll services for small and medium-sized businesses. With a people-first approach, Xenium helps organizations create thriving work environments where employees feel valued and supported. From navigating compliance to enhancing workplace culture, Xenium offers tailored solutions that empower growth and simplify HR. Discover how Xenium can transform your workplace:

Randy Boner, Associate Director of Client Success, shares real-world lessons from the front lines of reverification—how automation, payer mapping, and orchestration reduce rework, improve accuracy, and keep coverage continuous through the busiest time of year.Brought to you by www.infinx.com

ゲスト：安田菜津紀さん（フォトジャーナリスト） Frontline Session 2025/11/4/OA ＝＝ 発信型ニュース・プロジェクト「荻上チキ・Session」 ★月～金曜日　17:00～20:00　TBSラジオで生放送 パーソナリティ：荻上チキ、南部広美 番組HP：⁠⁠⁠⁠⁠⁠荻上チキ・Session⁠⁠⁠⁠⁠⁠ 番組メールアドレス：⁠⁠ss954@tbs.co.jp⁠⁠ 番組Xアカウント：⁠⁠⁠⁠⁠⁠@Session_1530⁠⁠⁠⁠⁠⁠ ハッシュタグ：⁠⁠⁠ ⁠⁠⁠#ss954⁠⁠⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

Segment 1: Interview with Joel Burleson-Davis Frontline workers can't afford to be slowed down by manual, repetitive logins, especially in mission-critical industries where both security and productivity are crucial. This segment will explore how inefficient login methods erode productivity, while workarounds like shared credentials increase risk, highlighting why passwordless authentication is emerging as a game-changer for frontline access to shared devices. Joel Burleson-Davis, Chief Technology Officer of Imprivata, will share how organizations can adopt frictionless and secure access management to improve both security and frontline efficiency at scale. Segment Resources: Putting Complex Passwords to Work For You This segment is sponsored by Imprivata. Visit https://securityweekly.com/imprivata to learn more about them! Topic Segment: The Economics of AI Agents Vendors are finding, after integrating agents into their processes, that agentic AI can get expensive very quickly. Of course, this isn't surprising when your goal is "review all my third party contracts and fill out questionnaires for me" and the pricing is X DOLLARS for 1M TOKENS blah blah context window, max model thinking model blah blah. No one knows what the conversion is from "review my contracts" to millions of tokens, so everyone is left to just test it out and see what the bill is at the end of the month. As we saw with Cloud when adoption started increasing in the early 2010s, we are naturally entering the era of AI cost optimization. In this segment, we'll discuss what that means, how it affects the market, and how it affects the use of AI in cybersecurity. Jackie mentions this story from Wired in the segment: https://www.wired.com/story/ai-bubble-will-burst/ News Segment Finally, in the enterprise security news, we've got funding and acquisitions 7 red flags you're doing cloud wrong security standards for open source projects post mortems of attacks on open source supply chain some analysis on current and historic AWS outages a deep dive some dumpster fires and how much would you pay for a robot that puts away the dishes? All that and more, on this episode of Enterprise Security Weekly. Visit https://www.securityweekly.com/esw for all the latest episodes! Show Notes: https://securityweekly.com/esw-431

In this episode of the Fitness + Technology Podcast, Bryan O'Rourke welcomes Brian Holmes, CEO and Founder of AI Front Desk. With hiring, training, and retaining frontline workers becoming increasingly challenging, AI Front Desk offers innovative artificial intelligence solutions that handle complex business tasks directly. By reducing dependence on traditional staffing models, the company helps streamline operations, improve efficiency, and minimize errors. Brian joins Bryan to discuss his company's approach and the practical impact these solutions are having across the industry. One Powerful Quote: 32:05: "Yes you can get to where you want to go. You just won't get there as fast as you want." 4-10 Bullet Points (w/ timestamps) - Highlighting key topics discussed: 2:47: Bryan opens the show by sharing Brian's entrepreneurial background. 8:42: Bryan asks Brian about the key lessons that led to the founding of AI Front Desk. 13:47: Bryan discusses the timeline behind launching AI Front Desk. 17:09: Brian addresses common misconceptions about agentic AI. 20:22: Brian outlines some of the core functions that AI Front Desk can perform. 25:33: Brian highlights the biggest challenges organizations face in adopting the technology. 31:20: Brian imparts his final pearls of wisdom to the listeners.  Bullet List of Resources: https://aifrontdesk.com/ Guest Contact Information: brian@aifrontdesk.com https://www.linkedin.com/in/brian-holmes-0a448566/ https://x.com/BrianAIFrontDsk https://www.bryankorourke.com/ https://www.linkedin.com/in/bryankorourke/ http://www.fittechcouncil.org/ https://www.youtube.com/user/bko61163

Segment 1: Interview with Joel Burleson-Davis Frontline workers can't afford to be slowed down by manual, repetitive logins, especially in mission-critical industries where both security and productivity are crucial. This segment will explore how inefficient login methods erode productivity, while workarounds like shared credentials increase risk, highlighting why passwordless authentication is emerging as a game-changer for frontline access to shared devices. Joel Burleson-Davis, Chief Technology Officer of Imprivata, will share how organizations can adopt frictionless and secure access management to improve both security and frontline efficiency at scale. Segment Resources: Putting Complex Passwords to Work For You This segment is sponsored by Imprivata. Visit https://securityweekly.com/imprivata to learn more about them! Topic Segment: The Economics of AI Agents Vendors are finding, after integrating agents into their processes, that agentic AI can get expensive very quickly. Of course, this isn't surprising when your goal is "review all my third party contracts and fill out questionnaires for me" and the pricing is X DOLLARS for 1M TOKENS blah blah context window, max model thinking model blah blah. No one knows what the conversion is from "review my contracts" to millions of tokens, so everyone is left to just test it out and see what the bill is at the end of the month. As we saw with Cloud when adoption started increasing in the early 2010s, we are naturally entering the era of AI cost optimization. In this segment, we'll discuss what that means, how it affects the market, and how it affects the use of AI in cybersecurity. Jackie mentions this story from Wired in the segment: https://www.wired.com/story/ai-bubble-will-burst/ News Segment Finally, in the enterprise security news, we've got funding and acquisitions 7 red flags you're doing cloud wrong security standards for open source projects post mortems of attacks on open source supply chain some analysis on current and historic AWS outages a deep dive some dumpster fires and how much would you pay for a robot that puts away the dishes? All that and more, on this episode of Enterprise Security Weekly. Visit https://www.securityweekly.com/esw for all the latest episodes! Show Notes: https://securityweekly.com/esw-431

Segment 1: Interview with Joel Burleson-Davis Frontline workers can't afford to be slowed down by manual, repetitive logins, especially in mission-critical industries where both security and productivity are crucial. This segment will explore how inefficient login methods erode productivity, while workarounds like shared credentials increase risk, highlighting why passwordless authentication is emerging as a game-changer for frontline access to shared devices. Joel Burleson-Davis, Chief Technology Officer of Imprivata, will share how organizations can adopt frictionless and secure access management to improve both security and frontline efficiency at scale. Segment Resources: Putting Complex Passwords to Work For You This segment is sponsored by Imprivata. Visit https://securityweekly.com/imprivata to learn more about them! Topic Segment: The Economics of AI Agents Vendors are finding, after integrating agents into their processes, that agentic AI can get expensive very quickly. Of course, this isn't surprising when your goal is "review all my third party contracts and fill out questionnaires for me" and the pricing is X DOLLARS for 1M TOKENS blah blah context window, max model thinking model blah blah. No one knows what the conversion is from "review my contracts" to millions of tokens, so everyone is left to just test it out and see what the bill is at the end of the month. As we saw with Cloud when adoption started increasing in the early 2010s, we are naturally entering the era of AI cost optimization. In this segment, we'll discuss what that means, how it affects the market, and how it affects the use of AI in cybersecurity. Jackie mentions this story from Wired in the segment: https://www.wired.com/story/ai-bubble-will-burst/ News Segment Finally, in the enterprise security news, we've got funding and acquisitions 7 red flags you're doing cloud wrong security standards for open source projects post mortems of attacks on open source supply chain some analysis on current and historic AWS outages a deep dive some dumpster fires and how much would you pay for a robot that puts away the dishes? All that and more, on this episode of Enterprise Security Weekly. Show Notes: https://securityweekly.com/esw-431

ゲスト：北丸雄二さん（ジャーナリスト） 2025年11月3日（月）「FrontLine Session」より ※荻上チキさんはお休み 発信型ニュース・プロジェクト「荻上チキ・Session」 ★月～金曜日　17:00～20:00　TBSラジオで生放送 パーソナリティ：荻上チキ、南部広美 番組HP：⁠荻上チキ・Session⁠ 番組メールアドレス：⁠ss954@tbs.co.jp⁠ 番組Xアカウント：⁠@Session_1530⁠ ハッシュタグは ⁠#ss954 Learn more about your ad choices. Visit megaphone.fm/adchoices

Segment 1: Interview with Joel Burleson-Davis Frontline workers can't afford to be slowed down by manual, repetitive logins, especially in mission-critical industries where both security and productivity are crucial. This segment will explore how inefficient login methods erode productivity, while workarounds like shared credentials increase risk, highlighting why passwordless authentication is emerging as a game-changer for frontline access to shared devices. Joel Burleson-Davis, Chief Technology Officer of Imprivata, will share how organizations can adopt frictionless and secure access management to improve both security and frontline efficiency at scale. Segment Resources: Putting Complex Passwords to Work For You This segment is sponsored by Imprivata. Visit https://securityweekly.com/imprivata to learn more about them! Topic Segment: The Economics of AI Agents Vendors are finding, after integrating agents into their processes, that agentic AI can get expensive very quickly. Of course, this isn't surprising when your goal is "review all my third party contracts and fill out questionnaires for me" and the pricing is X DOLLARS for 1M TOKENS blah blah context window, max model thinking model blah blah. No one knows what the conversion is from "review my contracts" to millions of tokens, so everyone is left to just test it out and see what the bill is at the end of the month. As we saw with Cloud when adoption started increasing in the early 2010s, we are naturally entering the era of AI cost optimization. In this segment, we'll discuss what that means, how it affects the market, and how it affects the use of AI in cybersecurity. Jackie mentions this story from Wired in the segment: https://www.wired.com/story/ai-bubble-will-burst/ News Segment Finally, in the enterprise security news, we've got funding and acquisitions 7 red flags you're doing cloud wrong security standards for open source projects post mortems of attacks on open source supply chain some analysis on current and historic AWS outages a deep dive some dumpster fires and how much would you pay for a robot that puts away the dishes? All that and more, on this episode of Enterprise Security Weekly. Show Notes: https://securityweekly.com/esw-431

Doug Keck stops in to tell us what's on the air on EWTN. Cindy Morales visits to highlight her documentary upcoming on EWTN TV, "Fake Clinics?". Plus, Joe Reciniello joins Teresa to to talk about his new book "Catholic Men Will Change America: Advent Reflection from the Front LIne", and T Two Sense looks over Erika Kirk's recent speech to Gen Z at the University of Mississippi.

With three FIU (financial intelligence unit) leadership positions under his belt, and much more besides, Daniel Thelesklaf shares his varied and valued experience in tackling financial crime. In this latest episode of the STR podcast, host Tom Keatinge catches up with Daniel Thelesklaf, long-time friend of RUSI's Centre for Finance and Security. Through FIU leadership positions from Liechtenstein to Germany via Switzerland, and roles as the Moneyval president, the Director of the UN University Finance Against Slavery and Trafficking programme and, now, Egmont vice-chair (not to mention starting life as a compliance officer in the Swiss banking industry), there is not much Daniel has not seen in the financial crime world. Here he shares the lessons he has learned.

At the Crexendo UGM, Dave Michels, Principal Analyst & Founder of TalkingPointz, sat down with Doug Green, Publisher of Technology Reseller News, to unpack “UCaaS Mobility 3” — a pragmatic, mobile-first model that moves enterprise calling from over-the-top apps to the cellular layer itself. Michels framed three generations of UCaaS mobility. Mobility 1 (find-me/follow-me) forwarded calls but split voicemail and caller ID. Mobility 2 (OTT softphone apps) worked well on strong internet — but faltered in truly mobile conditions (highway handoffs, variable coverage), pushing users back to personal cell numbers. Mobility 3 fixes this by placing the enterprise line on the SIM/eSIM: users choose business or personal at dial time, and enterprise calls ride native cellular voice for reliability, with full logging, recording, and policy control. The result: intuitive smartphone use (native dialer/contacts), optional UCaaS app, and clean work/personal separation without MDM intrusiveness. Michels highlighted why this matters now: Reliability on the move: Native cellular voice eliminates OTT fragility in transit. Compliance & CX: Enterprise calls and texts are captured and governed (finance, healthcare, education), and contact centers can transfer to subject-matter experts without losing recording/analytics. Frontline & deskless workers: Mobility-first roles (e.g., field services) can finally get enterprise-grade mobile that “just works.” Simplicity for IT & MSPs: One number can move across hard phone, soft client, and smartphone; less training and fewer behavior changes. Carrier convergence: With MVNO models (e.g., Crexendo's newly announced Xtend approach), service providers can bundle meetings, UCaaS, messaging, calling, and cellular — even globally — under a single brand and bill. Looking forward, Michels envisions “no more softphones” for many roles: users keep one phone, one dialer, two identities (business/personal), and enterprises preserve governance and data for AI-assisted analytics. For MSPs and resellers at UGM, the message was clear: Mobility 3 is a near-term, standard approach that elevates UCaaS into true mobile telephony, expands deal size and stickiness, and opens regulated and frontline segments. Explore more of Michels' analysis at TalkingPointz.

ゲスト：能條桃子さん（「NO YOUTH NO JAPAN」代表理事、「FIFTYS PROJECT」代表） 2025年10月30日（木）「FrontLine Session」より ========================================= 発信型ニュース・プロジェクト「荻上チキ・Session」 ★月～金曜日　17:00～20:00　TBSラジオで生放送 パーソナリティ：荻上チキ、南部広美 番組HP：⁠⁠⁠⁠荻上チキ・Session⁠⁠⁠⁠ 番組メールアドレス：⁠⁠⁠⁠ss954@tbs.co.jp⁠⁠⁠⁠ 番組Xアカウント：⁠⁠⁠⁠@Session_1530⁠⁠⁠⁠ ハッシュタグは ⁠⁠⁠⁠#ss954 Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of the Lead Ministry Podcast, Josh Denhart talks with Christen Clark, a seasoned children's ministry leader and host of The Collide Kids Podcast, about transforming “crowd-control” volunteers into front-line disciple-makers. Together they unpack practical ways to train, position, and encourage these often-overlooked team members so that every large-group experience thrives.If you've ever felt your program unravel during transitions or wished adults in the room would engage before things go sideways, this episode gives you a simple framework to elevate the whole experience.Key Topics Covered• Define the role: presence + engagement, not “warm bodies.”• Why engagement is contagious — adults model the room's posture.• The A-C-E framework: Affirm, Coach, Equip your volunteers every time.Key Quote“They're not the backup. They are the front line.” — Christen ClarkScripture References2 Peter 1 : 12-13 – “Stir them up by way of reminder.”Philippians 2 : 3-4 – Serving others with humble, attentive presence.TakeawayRecast “crowd control” as discipleship. Assign zones, learn names, close the distance, and model engagement. Then, weekly A-C-E your team: affirm their purpose, coach for the plan, equip with simple behaviors (proximity, participation, gentle prompts). The result is a calmer room, a clearer message, and better retention.Call to ActionWe hope this episode encourages and equips you. Share it with a friend and stay tuned for more resources each week.Christen Clark is a Christian speaker, worship leader, and children's ministry veteran with over 17 years of experience serving in the local church. She is the creator and host of The Collide Kids Podcast — a fun, faith-filled weekly show for kids and families launched in 2020 that helps parents and leaders spark spiritual conversations at home.Christen has served as a children's ministry leader, worship leader, and now works as a ministry consultant helping churches engage the next generation in faith. A graduate of Dallas Theological Seminary (2024), she lives in Cumming, Georgia, with her husband Richard and their two children.Her warm, creative style and gospel-centered approach make her a trusted voice for parents, pastors, and volunteers alike.Connect with Christen Clark

A leading authority on China's economy and financial system, Leland is the co-founder and CEO of China Beige Book International.Leland is a frequent commentator on media outlets such as CNBC, Bloomberg TV & Radio, CNN, BNN, BBC, and FOX Business, and he has served as a guest host of two of the financial world's top morning news shows, CNBC Squawk Box and Bloomberg Surveillance. His work is featured regularly in the Wall Street Journal, New York Times, Washington Post, TIME, New Yorker, The Atlantic, Forbes, Foreign Policy, The Hill, and South China Morning Post.Before co-founding China Beige Book in 2010, Leland was a capital markets attorney based out of New York and Hong Kong and worked on the deal team at a major investment bank. He holds a law degree from the University of Virginia School of Law, where he was Hardy C. Dillard fellow and editor-in-chief of the International Law Journal; a master's degree in Chinese History from Oxford University; a BA in European History from Washington & Lee University; and a graduate Chinese language fellowship from Tunghai University (Taiwan).Leland is an elected member of the National Committee on U.S.-China Relations and Economic Club of New York, an elected life member of the Council on Foreign Relations, a board member of the Global Interdependence Center, and a non-resident Senior Fellow at the Brent Scowcroft Center on International Security at the Atlantic Council. Learn more about your ad choices. Visit megaphone.fm/adchoices

Frontline's Michael Kirk discusses The Rise of RFK Jr., charting Kennedy's path from sex and drug addiction to what Kirk calls "an addiction to validation." He describes a man driven by grievance, and details how the alliance between Kennedy and Trump built the so-called "MAHA movement," and why it may collapse under its own contradictions. Plus: a breakdown of how Supreme Court shifts and redistricting could strip representation from Black voters in states like North Carolina and Louisiana. Produced by Corey Wara Production Coordinator Ashley Khan Email us at ⁠⁠⁠⁠thegist@mikepesca.com⁠⁠⁠⁠ To advertise on the show, contact ⁠⁠⁠⁠ad-sales@libsyn.com⁠⁠⁠⁠ or visit ⁠⁠⁠⁠https://advertising.libsyn.com/TheGist⁠⁠⁠⁠ Subscribe to The Gist: ⁠⁠⁠⁠https://subscribe.mikepesca.com/⁠⁠⁠⁠ Subscribe to The Gist Youtube Page: ⁠⁠⁠⁠https://www.youtube.com/channel/UC4_bh0wHgk2YfpKf4rg40_g⁠⁠⁠⁠ Subscribe to The Gist Instagram Page: ⁠⁠⁠⁠GIST INSTAGRAM⁠⁠⁠⁠ Follow The Gist List at: ⁠⁠⁠⁠Pesca⁠⁠⁠⁠ ⁠⁠⁠⁠Profundities | Mike Pesca | Substack

What happens when you grow up poor in America—and stay in touch with the same filmmaker for more than a decade? FRONTLINE filmmaker Jezza Neumann and documentary participant Kaylie Hegwood reflect on “Born Poor,” a film following three children, including Kaylie, from their lives as “Poor Kids” into young adulthood. Fourteen years after filming began, Neumann and Hegwood discuss poverty, perseverance, and what it really takes to break the cycle. Produced by Joel Patterson. Hosted by Raney Aronson-Rath.Watch the full documentary, Born Poor, on FRONTLINE's YouTube channel and PBS.org.Want to be notified every time a new podcast episode drops? Sign up for The FRONTLINE Dispatch newsletter.

Day 1,329.Today, as Donald Trump vows to harness the momentum of the Gaza ceasefire to bring peace to Ukraine, we examine global reaction – or the striking silence – after a UN convoy was attacked by Russian forces. Then we assess reports of a possible chemical weapons attack in Donetsk and take a deep dive into stories emerging from inside Russia – revealing the cracks in its economy and the growing strains within its society.Contributors:Francis Dearnley (Executive Editor for Audio). @FrancisDearnley on X.Dominic Nicholls (Associate Editor of Defence). @DomNicholls on X.Hamish de Bretton-Gordon (Chemical Weapons Expert and Former Tank Commander). @hamishdbg on X.James Kilner (Former Telegraph Russia Correspondant). @jkjourno on X.MORE TICKETS JUST RELEASED FOR 'UKRAINE: THE LATEST' LIVE, IN-PERSON:Join us for an in-person discussion and Q&A at the distinguished Honourable Artillery Company in London on 22nd October starting at 7pm.Our panel includes General Sir Richard Barrons, former head of UK Joint Forces Command and latterly one of the authors of Britain's Strategic Defence Review, and Orysia Lutsevych, head of the Ukraine Forum at the Chatham House think tank. Tickets are open to everybody and can be purchased at: https://www.squadup.com/events/ukraineliveSIGN UP TO THE ‘UKRAINE: THE LATEST' WEEKLY NEWSLETTER:http://telegraph.co.uk/ukrainenewsletter Each week, Dom Nicholls and Francis Dearnley answer your questions, provide recommended reading, and give exclusive analysis and behind-the-scenes insights – plus maps of the frontlines and diagrams of weapons to complement our daily reporting. It's free for everyone, including non-subscribers.CONTENT REFERENCED:Trump: Now let's end the Ukraine war (The Telegraph):https://www.telegraph.co.uk/us/news/2025/10/13/trump-threatens-putin-sending-tomahawks/Frontline report: Ukraine's kill zone takes shape in Sumy Oblast—Russians trapped in Yunakivka say hope is gone (Euromaidan):https://euromaidanpress.com/2025/10/12/frontline-report-ukraines-kill-zone-takes-shape-in-sumy-oblast-russians-trapped-in-yunakivka-say-hope-is-gone/UN CONVOY CAME UNDER ATTACK WHILE DELIVERING AID TO A FRONT-LINE COMMUNITY IN THE KHERSON REGION (United Nations):https://ukraine.un.org/en/303211-un-convoy-came-under-attack-while-delivering-aid-front-line-community-kherson-region Hosted on Acast. See acast.com/privacy for more information.