Podcasts about Acute

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Best podcasts about Acute

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Latest podcast episodes about Acute

Shift with CJ
Day 3: Why You're Bloated: Inflammation Explained (And Fixed)

Shift with CJ

Play Episode Listen Later Jul 8, 2025 9:55


In Day 3 of the Shift with CJ podcast, this episode helps you understand what inflammation really is, the difference between acute and chronic inflammation, how it impacts fat loss and hormones, and what you can start doing today to heal from the inside out.What You'll Learn:What Inflammation Actually Is CJ uses simple metaphors to explain how acute inflammation is a healing signal from the body (like when you stub your toe), while chronic inflammation is like an unwanted houseguest who refuses to leave—and slowly wrecks the place. Chronic inflammation messes with hunger hormones like insulin and leptin, making fat loss harder and hunger constant.Top Causes of InflammationProcessed seed oils (canola, sunflower, peanut)Sugar and its hidden forms (e.g., high fructose corn syrup)Refined carbs (pastries, bread, sugary snacks)AlcoholProcessed meats (bacon, sausages)CJ's Approved Cooking Fats For cooking, switch to stable fats like coconut oil, ghee, or butter. When eating out, ask for food cooked in olive oil or ghee instead of vegetable oils.Foods That Heal Inflammation and Burn Fat Nature has given us plenty of inflammation-fighting, fat-burning foods:Avocados: rich in healthy fats that support metabolismBerries: full of antioxidants that stabilize blood sugarApples & pears: fiber-rich for satietyGrapefruit: helps reduce appetite via GLP-1Sweet potatoes: steady your blood sugarCruciferous veggies (broccoli, cauliflower): loaded with nutrientsChili peppers: boost metabolismWild-caught salmon & fatty fish: loaded with omega-3sApple cider vinegar: improves insulin sensitivityMatcha and green tea: rich in antioxidantsGreek yogurt (if tolerated): supports gut healthNuts like pistachios and macadamias: nutrient-dense, but best kept to 10 per servingKey Takeaways:Inflammation is a signal, not the enemy. Acute inflammation heals. Chronic inflammation harms.What you eat matters. Cooking oils, added sugars, and processed foods are major inflammation triggers.Hormones are involved. Chronic inflammation distorts hunger and fullness signals, making it harder to lose weight.Nature has answers. Whole foods with fiber, antioxidants, and healthy fats can dramatically reduce inflammation.Bloating is a symptom. If you feel gassy, heavy, or inflamed, your gut and metabolism are asking for a reset.5 Things to Start Doing Today:Audit your pantry. Remove seed oils, processed meats, and sugary snacks. Replace them with clean alternatives.Switch your cooking oils. Use ghee, butter, or coconut oil at home and ask restaurants to avoid vegetable oils.Add inflammation-fighting foods to your meals. Aim for at least 3 from CJ's list each day (e.g., berries, salmon, cruciferous veggies).Start your meals with a shot of apple cider vinegar and lemon. Do it 20–30 minutes before eating to stabilize blood sugar.Track what you eat for a few days. Reflect on how foods make you feel—bloating, mood, energy—and start connecting the dots.Final Thought: Inflammation isn't the enemy—it's a signal that your body needs support. Start listening to it, nourishing it, and healing it one choice at a time

Talk Ten Tuesdays
Artificial Intelligence and Medical Record Coding

Talk Ten Tuesdays

Play Episode Listen Later Jul 8, 2025 32:31


Artificial intelligence (AI) has quickly transitioned from something to expect in the future to the here and now today. The potential for AI in health information is both exciting and daunting. Reporting the lead story during the next live edition of Talk Ten Tuesday will be longtime RACmonitor and ICD10monitor contributing author Sharon Easterling.Sharon Easterling is slated to create an editorial series on artificial intelligence. Her report on this topic will be a preview of what readers and listeners will learn during her series.The popular Internet broadcast will also feature these additional instantly recognizable panelists, who will report more news during their segments:• Social Determinants of Health: Tiffany Ferguson, CEO for Phoenix Medical Management, Inc., will report on the news that is happening at the intersection of medical record auditing and the SDoH;• The Coding Report: Christine Geiger, Assistant Vice President of Acute and Post-Acute Coding Services for First Class Solutions, will report on the latest coding news;• Field Report: Dennis Jones, a veteran Monitor Mondays and Talk Ten Tuesdays contributing author, will report on the latest developments regarding the revenue cycle. Jones is the senior director of revenue cycle at Jefferson Health.• News Desk: Timothy Powell, ICD10monitor national correspondent, will anchor the Talk Ten Tuesdays News Desk; and• MyTalk: Angela Comfort, veteran healthcare subject-matter expert, will co-host the long-running and popular weekly Internet broadcast. Comfort is the Assistant Vice President of Revenue Integrity for Montefiore Health.

Help and Hope Happen Here
Heather Lino will talk about her son James who was diagnosed with T Cell Acute Lymphoblastic Lymphoma when he was 3 years old in 2020 and also was diagnosed with the almost unheard of Ring Chromosome 14 syndrome

Help and Hope Happen Here

Play Episode Listen Later Jul 7, 2025 48:23


Heather Lino's then 3 year old son James was given a double whammy in 2020 when he was first diagnosed with T Cell Acute Lymphoblastic Lymphoma in July, and then roughly one month into his treatment he was diagnosed with a Chromosomal disorder known as Ring 14 Syndrome. This disorder affects 200-250 people around the world. This affliction causes seizures and intellectual disabilities and can have other problems associated with it as well. James is now 8 years old and is living his best life possible. 

Neurology Minute
Outcomes Following Acute Plasma Exchange for MOGAD - Part 1

Neurology Minute

Play Episode Listen Later Jul 4, 2025 3:08


In part one of this three-part series, Dr. Justin Abbatemarco and Drs. John Chen and Smathorn Thakolwiboon discuss the outcomes following plasma exchange in MOGAD and explore how the findings from this study can inform patient care. 

Neurology® Podcast
Outcomes Following Acute Plasma Exchange for MOGAD

Neurology® Podcast

Play Episode Listen Later Jul 3, 2025 17:36


Dr. Justin Abbatemarco talks with Drs. John Chen and Smathorn Thakolwiboon about the outcomes following plasma exchange in MOGAD and explore how the findings from this study can inform patient care.  Disclosures can be found at Neurology.org. 

The Medbullets Step 2 & 3 Podcast
Gastrointestinal | Acute Hepatitis

The Medbullets Step 2 & 3 Podcast

Play Episode Listen Later Jul 3, 2025 13:20


In this episode, we review the high-yield topic Acute Hepatitis ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠from the Gastrointestinal section at ⁠⁠⁠⁠Medbullets.com⁠⁠⁠⁠⁠⁠Follow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbulletsLinkedin: https://www.linkedin.com/company/medbullets

Behind The Knife: The Surgery Podcast
Intern Bootcamp: Medical Students

Behind The Knife: The Surgery Podcast

Play Episode Listen Later Jul 2, 2025 17:11


RE-RELEASE This was first published in 2023 but it's so good we are running it back! Buckle up, PGY-1's! Intern year is starting whether you're ready or not. Don't fret, BTK has your back to make sure you dominate the first year of residency.  You've been a doctor for about 3.5 seconds, and suddenly that bright eyed, bushy-tailed medical student on service is looking to you for advice? Don't fret, in this episode we'll give you some tips for how to handle it. Hosts: Shanaz Hossain, Nina Clark Tips for new interns: REMEMBER HOW INTERNS DO AND DO NOT TEACH - Nobody, not even the med students, expect you to be an expert in everything or give a fully-planned formal lecture - You WILL however spend a ton of time working with students on your team – and via modeling and teachable moments, you can help them learn how it's done! MODELING - Remember how hard everything has been in the few days since you started residency? Think about all the information you've picked up, tips and tricks you're developing for efficiency, and best practices you're learning in the care of your patients. ALL of these are things you can pass on to students. - Presentations, case prep, answering questions from senior members of the team are ALL excellent opportunities to teach (and show students how you learn yourself, so they can do it independently). TEACHABLE MOMENTS - Find small topics that you know or are getting to know well – things like looking at a CXR, CT scan, etc. - Once you're getting more comfortable caring for specific disease processes, think about high yield lessons for students: - Acute trauma evaluation and management (ABCDE's), appendicitis, diverticulitis, benign biliary disease all make great 5 minute chalk talks that you can have in your back pocket IN THE OR - Watch students practice skills, and try to give some feedback and tips that you use (you learned knot tying and suturing more recently than ANYONE else in the OR and probably have some tips that you're still using to improve) - If you're not sure where or why the student is struggling with a particular skill (like tying a knot), model doing it yourself in slow motion while watching them do it – often the side by side comparison can help you identify where they're going astray BE THE RESIDENT YOU WISH YOU HAD - Refer to EVERYONE with respect - Model being a kind, conscientious, and curious physician - Try to find universal lessons and crossover topics that non-surgeons need to know - A great student makes their interns look even better – be explicit about how they can be successful, then advocate for them to have opportunities to show everything they're learning! Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more. If you liked this episode, check out our new how-to video series on suture and knot-tying skills – https://behindtheknife.org/video-playlists/btk-suture-practice-kit-knot-tying-simulator-how-to-videos/

the orthoPA-c
A Case Study - Osteopenia, Sudden Acute Groin Pain and Hip Pain

the orthoPA-c

Play Episode Listen Later Jul 2, 2025 7:58


Sam shares a case of a 72 year old patient presenting with groin pain and with xrays that reveal osteopenia. What further imaging is indicated? What is important to address while they are at urgent care?

The SHIFT Show
Why Acute Injury/Post Op Surgery PT is Key

The SHIFT Show

Play Episode Listen Later Jul 1, 2025 33:31 Transcription Available


Every day we pay our dues by doing the harder thing when it's the right thing to do, especially when managing the complicated early weeks of post-operative rehabilitation. • Understanding surgical procedures through observation, surgical textbooks, and building relationships with surgeons• Establishing direct communication with surgeons to obtain critical information rather than navigating complex administrative channels• Managing pain through appropriate medication, consistent icing, and education about maintaining comfort• Controlling swelling with compression, elevation, and controlled movement to prevent quadriceps inhibition• Prioritizing full hyperextension for knee surgeries to prevent complications like cyclops lesions• Using "consistency over intensity" approach with gentle, frequent interventions rather than aggressive stretching• Activating key muscles through neuromuscular electrical stimulation (NMES) in conjunction with volitional efforts• Progressing from assistive devices based on functional criteria rather than arbitrary timeframes• Applying similar systematic principles across different joints with appropriate modifications for specific procedures• Focusing on early hip labral repair rehabilitation with controlled motion and gradual progressionWe appreciate you listening! To learn more about SHIFT, head here - https://shiftmovementscience.com/To learn about SHIFT's courses, check our website here - https://courses.shiftmovementscience.com/Also, please consider rating, reviewing, and sharing the podcast with your friends! Thanks :)Thanks for listening to The SHIFT Show! Check out SHIFT's most popular courses here! https://courses.shiftmovementscience.com/Want to join our online educational community of over 1000 gymnastics professionals and get 40+ hours of gymnastics lectures? Join The Hero Lab below!https://shiftmovementscience.com/theherolab/ Check out all our past podcast episodes here!https://shiftmovementscience.com/podcast/

PsychEd: educational psychiatry podcast
PsychEd Episode 67: Catatonia with Dr. Patricia Rosebush

PsychEd: educational psychiatry podcast

Play Episode Listen Later Jul 1, 2025 61:07


Welcome to PsychEd, the psychiatry podcast for medical learners, by medical learners.This episode covers catatonia with Dr. Patricia Rosebush. Dr. Rosebush is a Professor in the Department of Psychiatry & Behavioural Neurosciences at McMaster University. She is the distinguished author of numerous articles on clinical neuroscience, including considerable work on mitochondrial disorders in mental illness and over 30 papers on catatonia, and practices consultation-liaison psychiatry at St. Joseph's Healthcare Hamilton.The learning objectives for this episode are as follows:By the end of this episode, the listener will be able to…Develop a conceptual understanding of catatoniaHave an approach for diagnosing catatoniaHave an approach for treating catatoniaGuest: Dr. Patricia RosebushHosts: Dr. Alastair Morrison (PGY1), Dr. Angad Singh (PGY1)Audio editing: Dr. Angad SinghShow notes: Dr. Alastair MorrisonInterview content:(01:20) Clinical features of catatonia (high level overview)(04:15) Clinical anecdote - an index case of catatonia(06:00) History of approaches to catatonia(10:00) Approach to different catatonia phenotypes(15:00) Categorization and ideas of mechanism(18:00) Assessing clinical signs of catatonia (24:00) Preserved awareness in catatonia(27:00) Investigations and differential diagnosis(30:00) First interventions: benzodiazepines and benzodiazepine withdrawal(41:30) Managing medical considerations in catatonia(45:00) Treating other psychiatric illnesses in the catatonic patient(49:00) Acute, chronic, and refractory treatmentsReferences:Barnes MP, Saunders M, Walls TJ, Saunders I, Kirk CA. The syndrome of Karl Ludwig Kahlbaum. J Neurol Neurosurg Psychiatry. 1986 Sep;49(9):991-6. https://doi.org/10.1136/jnnp.49.9.991Bush G, Fink M, Petrides G, Dowling F, Francis A. Catatonia. I. Rating scale and standardized examination. Acta Psychiatr Scand. 1996 Feb;93(2):129-36. https://doi.org/10.1111/j.1600-0447.1996.tb09814.xPsychDB. (2023, November 23). Catatonia. https://www.psychdb.com/cl/0-catatoniaRosebush PI, Mazurek MF. Catatonia and its treatment. Schizophr Bull. 2010 Mar;36(2):239-42. https://doi.org/10.1093/schbul/sbp141For more PsychEd, follow us on Instagram (@psyched.podcast),  Facebook (PsychEd Podcast), X (@psychedpodcast), and Bluesky (@psychedpodcast.bsky.social‬). You can email us at psychedpodcast@gmail.com and visit our website at psychedpodcast.org.

Talk Ten Tuesdays
New Coding Challenges for Reporting Gender-Affirming Care

Talk Ten Tuesdays

Play Episode Listen Later Jul 1, 2025 30:19


As state laws, federal regulations, and insurance policies continue to evolve, healthcare organizations face growing demands to ensure that gender-affirming care is appropriately documented and reported.Reporting on these serious coding challenges and the dire consequences of failing to achieve compliance during the next edition of Talk Ten Tuesdays will be senior healthcare consultant Penny Jefferson, the special guest for the broadcast coming up at 10 a.m. EST on Tuesday, July 1.The popular Internet broadcast will feature the additional following instantly recognizable panelists, who will report more news during their segments:• CDI Report: Cheryl Ericson, Director of Clinical Documentation Integrity (CDI) for the vaunted Brundage Group, will have the latest CDI updates;• The Coding Report: Christine Geiger, Assistant Vice President of Acute and Post-Acute Coding Services for First Class Solutions, will report on the latest coding news;• News Desk: Timothy Powell, ICD10monitor national correspondent, will anchor the Talk Ten Tuesdays News Desk; and• MyTalk: Angela Comfort, veteran healthcare subject-matter expert, will co-host the long-running and popular weekly Internet broadcast. Comfort is the Assistant Vice President of Revenue Integrity for Montefiore Health.

Rheuminations
The Tumultuous Tale of Th17-and the IL23/IL17 immune axis

Rheuminations

Play Episode Listen Later Jun 30, 2025 42:40


In this episode, we dive into a two-part story of intrigue starting from a paradigm shift in understanding of T cell biology because of a mouse model of post-measles encephalopathy, to the eventual recognition of the IL-23/17 immune axis. •    Intro 0:01 •    In this episode 0:12  •    Interleukin-17 (IL-17) is a relatively recent discovery 1:34 •    The beginning of TH-17 2:20 •    Looking at autoimmune encephalopathy: A story of measles 03:30 •    1790's woman with post measles inflammatory process in the brain 10:26 •    What is causing post-infection encephalitis? 12:00 •    Acute disseminated encephalomyelitis 12:30 •    How did we find out the immune system was behind this - The rabies vaccine 13:09 •    Similarity between the rabies vaccine and infections like measles 16:04 •    T-cell lymphocytes 17:12 •    The forgotten thymus 18:00 •    What's the function of T-cells? 19:35 •    How do you tell T-cells apart? 21:14 •    The Human Leukocyte Differentiation Antigens Party 24:05 •    The godfather of T-cells 24:45 •    The TH-1 and TH-2 axis 27:30 •    Experimental Autoimmune Encephalomyelitis model screwed everything up 29:16 •    Interferon gamma 32:32 •    What's missing? IL-23 surprise 33:40 •    IL-17 in the 1990's 36:44 •    The world is introduced to TH-17 39:12 •    Let's recap what we learned 40:30 •    That is the end! 42:30 •    Thanks for listening 42:39 We'd love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum. References: Bashyam H. J Exp Med. 2007;doi:10.1084/jem.2042fta Bennetto L, et al. J Neurol Neurosurg Psychiatry. 2004;doi:10.1136/jnnp.2003.034256 Berche P. Presse Med. 2022;doi:10.1016/j.lpm.2022.104149 El-behi M, et al. J Neuroimmune Pharmacol. 2010;doi:10.1007/s11481-009-9188-9 Gooderham MJ, et al. J Eur Acad Dermatol Venereol. 2018;doi:10.1111/jdv.14868 Hawkes JE, et al. J Immunol. 2018;doi:10.4049/jimmunol.1800013 Rogozynski N, et al. Immunol Lett. 2024;doi:10.1016/j.imlet.2024.106870 Sospedra M, et al. Annu Rev Immunol. 2005;doi:10.1146/annurev.immunol.23.021704.115707 Steinman L. Nat Med. 2007;doi:10.1038/nm1551 Disclosures: Brown reports no relevant financial disclosures.

CLOT Conversations
The COBRA Study: Shifting Paradigms in Acute VTE Treatment

CLOT Conversations

Play Episode Listen Later Jun 27, 2025 4:34


Send us a textIn this episode of Clot Conversations, Dr. Lana Castellucci, University of Ottawa, discusses the COBRA study, which compares the bleeding risks of rivaroxaban and apixaban in patients with acute VTE. The study follows patients for three months and finds that apixaban significantly reduces combined bleeding events compared to rivaroxaban. While the trial wasn't powered for individual outcomes, it shows no difference in VTE recurrence. This is potentially practice-changing information, indicating that most acute VTE patients might benefit from apixaban over rivaroxaban, although patient-specific factors and preferences will still play a role in decision-making.Support the showhttps://thrombosiscanada.caTake a look at our healthcare professional and patient resources, videos and publications on thrombosis from the expert members of Thrombosis Canada

New: Football Clichés
5-a-side injury updates & watching TV football from an acute angle: The listeners' loves & hates

New: Football Clichés

Play Episode Listen Later Jun 25, 2025 67:57


Adam Hurrey, Charlie Eccleshare and David Walker entertain this month's listener entries for Mesut Haaland Dicks, as the Clichés faithful nominate their niche footballing fascinations and irritations. Among the selections are the injury reports in 5-a-side group chats, players who look like they think throw-ins are beneath them, the horror of watching a game on a TV from an angle of less than 40 degrees and the unsatisfying asterisk that looms over at least half a dozen major international tournament winners since 1954. Meanwhile, the Adjudication Panel ponder how many departing players make an "exodus". Sign up for Dreamland, the new members-only Football Clichés experience, to access our exclusive new show and much more: https://dreamland.footballcliches.com Get your ticket for the Football Clichés Live tour this October: https://myticket.co.uk/artists/football-cliches-live Learn more about your ad choices. Visit podcastchoices.com/adchoices

JACC Speciality Journals
Safety and Feasibility of On-the-Table Pharmacomechanical Lysis for Acute Intermediate-Risk Pulmonary Embolism: The RESCUE-II Study | JACC: Advances

JACC Speciality Journals

Play Episode Listen Later Jun 25, 2025 2:46


Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Safety and Feasibility of On-the-Table Pharmacomechanical Lysis for Acute Intermediate-Risk Pulmonary Embolism: The RESCUE-II Study.

Neurology Minute
Acute Symptomatic Seizures During CAR T-Cell Therapy for Hematologic Malignancies - Part 2

Neurology Minute

Play Episode Listen Later Jun 24, 2025 1:32


In the second installment of this two-part series, Dr. Jeff Ratliff and Dr. Brin E. Freund discuss clinical guidance for managing patients who may experience neurotoxicity from CAR T-cell, with a specific focus on seizure risk.  Show reference:  https://www.neurology.org/doi/10.1212/WNL.0000000000213535 

Talk Ten Tuesdays
Is there a Code for Probiotic Dispensers?

Talk Ten Tuesdays

Play Episode Listen Later Jun 24, 2025 23:50


Your pets might be doing more than just keeping you company. They could be reshaping your immune system.Early exposure to pets, especially in childhood, may reduce allergies and asthma by diversifying gut bacteria and strengthening immunity, according to Dr. Nick van Terheyden, director of Incremental Health. Dr. Nick is scheduled to be the special guest during the next live edition of Talk Ten Tuesdays, coming up at 10 a.m. EST on Tuesday, June 24.The popular Internet broadcast will feature the additional following instantly recognizable panelists, who will report more news during their segments:• CDI Report: Cheryl Ericson, Director of Clinical Documentation Integrity (CDI) for the vaunted Brundage Group, will have the latest CDI updates;• The Coding Report: Christine Geiger, Assistant Vice President of Acute and Post-Acute Coding Services for First Class Solutions, will report on the latest coding news;• News Desk: Timothy Powell, ICD10monitor national correspondent, will anchor the Talk Ten Tuesdays News Desk; and• MyTalk: Angela Comfort, veteran healthcare subject-matter expert, will co-host the long-running and popular weekly Internet broadcast. Comfort is the Assistant Vice President of Revenue Integrity for Montefiore Health.

RCP Medicine Podcast
Episode 85: IBD - Crohn's disease (part 2)

RCP Medicine Podcast

Play Episode Listen Later Jun 24, 2025 24:55


In this episode of the RCP Medicine podcast, Professor Ailsa Hart and Dr Eathar Shakweh discuss how to approach managing Inflammatory Bowel Disease (IBD) in the acute medical setting. This is the second episode of a 2-part series, with a focus on Crohn's disease. IBD is a common condition, affecting 1 in 123 people in the UK. The 2024 State of the IBD Care in the UK report highlighted the urgent need to shorten time to diagnosis and initiate early treatment to minimise the risk of IBD-related complications. Acute and general medicine physicians have an important role to play in diagnosing and managing IBD. This podcast will equip medics at all stages of training with the necessary knowledge to approach this heterogenous and complex condition. Professor Hart is Director of IBD Research at St Mark's Hospital, London, United Kingdom and a world-leading expert in IBD. Eathar is an IBD Clinical Research Fellow at St Mark's and Imperial, with a special interest in perianal fistulising Crohn's disease. Crohn's & Colitis UK (CCUK) Websitehttps://crohnsandcolitis.org.uk/This is a valuable resource for patients and healthcare professionals alike, containing a wealth of information on IBD investigation and management.British Society of Gastroenterology (BSG) guidelines on Inflammatory Bowel Disease (IBD) - 2019Lamb, Christopher Andrew et al. “British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults.” Gut vol. 68,Suppl 3 (2019): s1-s106. doi:10.1136/gutjnl-2019-318484https://pubmed.ncbi.nlm.nih.gov/31562236/For interested listeners, these are the national guidelines for IBD diagnosis and management. Please note, the new guidelines for 2025 are pending release.ECCO Guidelines on Therapeutics in Crohn's disease: Medical TreatmentTorres, Joana et al. “ECCO Guidelines on Therapeutics in Crohn's Disease: Medical Treatment.” Journal of Crohn's & colitis vol. 14,1 (2020): 4-22. doi:10.1093/ecco-jcc/jjz180https://pubmed.ncbi.nlm.nih.gov/38877997/ECCO Guidelines on Surgery in Crohn's disease: Surgical TreatmentAdamina, Michel et al. “ECCO Guidelines on Therapeutics in Crohn's Disease: Surgical Treatment.” Journal of Crohn's & colitis vol. 18,10 (2024): 1556-1582. doi:10.1093/ecco-jcc/jjae089https://pubmed.ncbi.nlm.nih.gov/38878002/These are the European Crohn's and Colitis Organisation (ECCO) guidelines on therapeutics in Crohn's disease, divided into medical and surgical treatment.RCPEducation and learning | RCP CreditsMusic bensound.com

Power Supply
Real-Time Logistics: Automating Non-Acute Supply Management

Power Supply

Play Episode Listen Later Jun 23, 2025 35:50


Is your team spending hours driving from site to site just to check inventory levels? On this Season 14 finale of Power Supply, we welcome Alex VandenBroek from MultiCare and Guy Russell from VUEMED to explore how electronic shelf labels are transforming non-acute logistics across multiple locations. From eliminating daily drives to numerous locations to enabling real-time ordering through a simple button press, our guests share how this technology frees up valuable staff time while improving visibility and communication with clinical teams. If you're managing multiple sites or looking to deploy your human resources more strategically, tune in to hear Alex and Guy reveal how they turned routine inventory management into an automated success story that builds trust and delivers measurable efficiency gains! Once you complete the interview, jump on over to the link below to take a short quiz and download your CEC certificate for 0.5 CECs! – https://www.flexiquiz.com/SC/N/ps14-08 #PowerSupply #Podcast #AHRMM #HealthcareSupplyChain #Inventory #Technology #NonAcuteLogistics

Neurology Minute
Acute Symptomatic Seizures During CAR T-Cell Therapy for Hematologic Malignancies - Part 1

Neurology Minute

Play Episode Listen Later Jun 20, 2025 1:39


In part one of this two-part series, Dr. Jeff Ratliff and Dr. Brin E. Freund discuss the incidence of acute symptomatic seizures during CAR T-cell therapy.  Show reference:  https://www.neurology.org/doi/10.1212/WNL.0000000000213535   

Rio Bravo qWeek
Episode 194: Acute Low Back Pain

Rio Bravo qWeek

Play Episode Listen Later Jun 20, 2025 18:55


Episode 194: Acute low back pain.  Future Dr. Ibrahim presents a clinical case to explain the essential points in the evaluation of back pain.  Future Dr. Redden adds information about differentiating between a back strain and more serious diseases such as cancer, and Dr. Arreaza shares information about returning to work after back strain.Written by Michael Ibrahim, MSIV. Editing and comments by Jordan Redden, MSIV, and Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.Dr. Arreaza:Welcome back, everyone. Today's topic is one that every primary care provider, emergency doctor, and even specialist sees routinely: low back pain. It's so common that studies estimate up to 80% of adults will experience it at some point in their lives. But despite how frequent it is, the challenge is to identify which cases are benign and which demand urgent attention.Jordan:Exactly. Low back pain is usually self-limiting and mechanical in nature, but we always need to keep an eye out for the rare but serious causes: things like infection, malignancy, or neurological compromise. That's why a good history and physical exam are our best tools right out of the gate.Michael:And to ground this in a real example, let me introduce a patient we saw recently. John is a 45-year-old warehouse worker who came in with two weeks of lower back pain that started after lifting a 50-lb box. He describes it as a dull, aching pain that radiates from his lower back down the posterior left thigh into the calf. He says it gets worse with bending or coughing, but he feels better when lying flat. He also mentioned some numbness in his left foot, but he denies any bowel or bladder issues. His vitals are completely normal. On exam, he had lumbar paraspinal tenderness, a positive straight leg-raise at 40 degrees on the left and decreased sensation in the L5 dermatome, though reflexes were still intact.Dr. Arreaza:That's a great case. Let's take a minute and talk about the straight leg raise test. This is a bedside tool we use to assess for lumbar nerve root irritation often caused by a herniated disc. ***Here's how it works: the patient lies supine, and you slowly raise their straight leg. If pain radiates below the knee between 30° and 70°, that suggests radiculopathy, especially involving the L5 or S1 nerve roots. Pain at higher angles is more likely due to hamstring tightness or mechanical strain.Michael:Right. So, stepping back: what do we mean by "low back pain"? Broadly, it's any pain localized to the lumbar spine, but it's often classified by type or cause:Mechanical (like muscle strain or degenerative disc disease), Radicular (nerve root involvement), Referred pain (like from pelvic or abdominal organs), Inflammatory (AS), and Systemic or serious causes like infection or malignancy. Jordan:In John's case, we're thinking radicular pain, most likely from a herniated disc compressing the L5 nerve root. That's supported by the dermatomal numbness, the leg pain, and that positive straight leg test.Dr. Arreaza:Good reasoning. Now, anytime we see back pain, our brains should run a checklist for red flags. These help us pick up more serious causes that require urgent attention. Let's run through the red flags.Michael:Sure. For fracture, we think about major trauma or even minor trauma in the elderly, especially those with osteoporosis or on chronic steroids. Also, anyone over 70 years old.Jordan:Then we have infections, which could include things like discitis, vertebral osteomyelitis, or epidural abscess. Red flags include fever, IV drug use, recent surgery, or immunosuppression.Michael:Malignancy is another critical one, especially if there's a history of breast, prostate, lung, kidney, or thyroid cancer. Clues include unexplained weight loss, night pain, or constant pain not relieved by rest.Jordan:And don't forget about inflammatory back pain, like ankylosing spondylitis, which is often seen in younger patients with morning stiffness that lasts more than 30 minutes and improves with activity.Dr. Arreaza:And of course, we always rule out cauda equina syndrome: a surgical emergency. That's urinary retention or incontinence, saddle anesthesia, bilateral leg weakness, or fecal incontinence. Missing this diagnosis can be catastrophic.Michael:Thankfully, in John's case, we don't see any red flags. His presentation is classic for uncomplicated lumbar radiculopathy. But we must stay vigilant, because sometimes patients don't offer up key symptoms unless we ask directly.Jordan:And that's where associated symptoms help guide us. For example:Radicular symptoms like numbness or weakness follow dermatomal patterns. Constitutional symptoms like fever or weight loss raise red flags. Bladder/bowel changes or saddle anesthesia raise alarms for cauda equina. Pain that wakes patients up at night might point to malignancy. Dr. Arreaza:So when do we order labs or imaging?Michael:Not right away. For most patients with acute low back pain, imaging is not needed unless they have red flags. If infection is suspected, we'd get CBC, ESR, and CRP. For cancer, maybe PSA or serum protein electrophoresis. And if inflammatory back disease is suspected, HLA-B27 can be helpful.Jordan:Yes, imaging should be delayed for at least six weeks unless red flags or significant neurologic deficits are present. When we do image, MRI is our go-to especially for suspected radiculopathy or cauda equina. X-rays can help if we're thinking about fractures, but they won't show soft tissue or nerve root issues.Michael:In the example from our case, since the patient doesn't have red flags, we'd go with conservative management: start NSAIDs and recommend activity modification. As this is the acute setting, physical therapy would not be recommended.Jordan:For the acute phase, research shows no serious difference between those with PT and those without in the long term. However, physical therapy is really the cornerstone of management for chronic back pain. It's not just movement: it's education, body mechanics, and teaching patients how to move safely. And PT can actually reduce opioid use, imaging, and injections down the line for patient struggling with long term back pain.Dr. Arreaza:Yes, and PT is not one-size-fits-all. PT might include McKenzie exercises, manual therapy, postural retraining, or even neuromuscular re-education. The goal is always to build core stability, promote healthy movement patterns, and reduce fear of motion.Jordan:Let's take a minute to talk about the McKenzie Method, a physical therapy approach used to treat lumbar disc herniation by identifying a specific movement, (often spinal extension) that reduces or centralizes pain. A common exercise is the prone press-up, (cobra pose for yoga fans) where the patient lies face down and pushes the upper body upward while keeping the hips on the floor to relieve pressure on the disc. These exercises should be done carefully, ideally under professional guidance, and discontinued if symptoms worsen.Michael:For our case patient, our working diagnosis is mechanical low back pain with L5 radiculopathy. No imaging needed now, no red flags. We'll treat conservatively and educate him about proper lifting, staying active, and recovery expectations.Jordan:We also emphasized to him that bed rest isn't helpful. In fact, bed rest can make things worse. Keeping active while avoiding heavy lifting for now is key.Dr. Arreaza:Return-to-work recommendations should be individualized. For example, an office worker, positioning while working, or work hours may be able to return to work promptly. However, those with physically demanding jobs may need light duty or be off work.Ice: no evidence of benefit. Heat: may reduce pain and disability in pain of less than 3 months, although the benefit was small and short.And we should always teach safe lifting techniques: bend at the knees, keep the load close, avoid twisting. It's basic knowledge, but it is very effective in preventing recurrence.Jordan:Now, if a patient fails to improve after 6 weeks of conservative therapy, or if they develop new neurologic deficits, that's when we think about referral to spine specialists or surgical consultation.Michael:And as previously mentioned: in cases where back pain becomes chronic (lasting more than 12 weeks) a multidisciplinary approach works best. That can include:Physical therapy, Cognitive behavioral therapy (CBT) And sometimes pain management interventions. Jordan:We can't forget the psychological toll either. Chronic back pain is associated with depression, anxiety, and opioid dependence. Increased risk factors include obesity, smoking, sedentary lifestyle, and previous back injuries.Dr. Arreaza:Well said. So, let's summarize. Michael?Michael:Sure! Low back pain is common, and most cases are benign. But we have to know the red flags that point to serious pathology. A focused history and physical exam are more powerful than many people realize. And the first step in treatment is almost always conservative, with a strong emphasis on maintaining physical activity.Jordan:And don't underestimate the value of patient education. Helping patients understand their pain, set realistic expectations, and stay active is often just as important as the medications or therapies we offer.Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References:Chou, R., Qaseem, A., Snow, V., Casey, D., Cross, J. T., Shekelle, P., & Owens, D. K. (2007). Diagnosis and treatment of low back pain: A joint clinical practice guideline from the American College of Physicians and the American Pain Society. Annals of Internal Medicine, 147(7), 478–491. https://doi.org/10.7326/0003-4819-147-7-200710020-00006Deyo, R. A., Mirza, S. K., Turner, J. A., & Martin, B. I. (2009). Overtreating chronic back pain: Time to back off? Journal of the American Board of Family Medicine, 22(1), 62–68. https://doi.org/10.3122/jabfm.2009.01.080102National Institute for Health and Care Excellence. (2020). Low back pain and sciatica in over 16s: Assessment and management (NICE Guideline No. NG59). https://www.nice.org.uk/guidance/ng59Qaseem, A., Wilt, T. J., McLean, R. M., & Forciea, M. A. (2017). Noninvasive treatments for acute, subacute, and chronic low back pain: A clinical practice guideline from the American College of Physicians. Annals of Internal Medicine, 166(7), 514–530. https://doi.org/10.7326/M16-2367UpToDate. (n.d.). Evaluation and treatment of low back pain in adults. Wolters Kluwer. https://www.uptodate.com (Access requires subscription)Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/. 

Neurology® Podcast
Acute Symptomatic Seizures During CAR T-Cell Therapy for Hematologic Malignancies

Neurology® Podcast

Play Episode Listen Later Jun 19, 2025 15:05


Dr. Jeff Ratliff talks with Dr. Brin E. Freund about the evaluated incidence and risk factors for acute symptomatic seizures during CAR T-cell therapy. Read the related article in Neurology®.  Disclosures can be found at Neurology.org. 

Wits & Weights: Strength and Nutrition for Skeptics
The REAL Triggers of Chronic Inflammation | Ep 336

Wits & Weights: Strength and Nutrition for Skeptics

Play Episode Listen Later Jun 18, 2025 16:36 Transcription Available


Join our free Facebook community at facebook.com/groups/witsandweights--Tired of the inflammation fear-mongering? Stop obsessing over "toxic" foods and learn what actually drives chronic inflammation in your body.While fitness influencers point fingers at gluten, seed oils, and nightshades, the real culprits are hiding in plain sight... and they're not what you think.This episode dismantles the myths surrounding inflammation and reveals the true drivers of this misunderstood health concern. While we're scrutinizing ingredient labels and avoiding specific foods, the actual causes of chronic inflammation are hiding in plain sight... and they have little to do with what's on your plate.Discover how to engineer an anti-inflammatory lifestyle using systems thinking instead of food perfectionism.Main Takeaways:Acute vs. chronic inflammation are completely different systems requiring different solutionsThe #1 driver of inflammation isn't foodsOne organ functions as your body's natural anti-inflammatory pharmacySpecific lifestyle factors matter more than eliminating specific foodsWestern dietary patterns drive inflammation, not individual ingredientsEpisode Resources:Try MacroFactor for free with code WITSANDWEIGHTS - Apple/iPhone or Google/AndroidTimestamps:0:00 - The inflammation myth 2:16 - Acute vs. chronic inflammation 3:39 - The real drivers of inflammation 5:31 - Why specific foods don't matter 8:42 - Engineering an anti-inflammatory lifestyle 12:13 - The anti-inflammatory organ you can develop 14:47 - Systems approach to inflammationSupport the show

Talking Points
Acute Coronary Care in Ethiopia

Talking Points

Play Episode Listen Later Jun 18, 2025 12:08


Mamas Mamas talks to Tesfaye Telila about the landscape of acute coronary care in Ethiopa, where just a few dozen cardiologists contend with a population of 120 million people.

Sigma Nutrition Radio
SNP41: Do Certain Foods Really Cause Inflammation – And Are Anti-Inflammatory Diets the Answer?

Sigma Nutrition Radio

Play Episode Listen Later Jun 17, 2025 16:19


Inflammation has become a nutrition buzzword, often used in extreme or misleading ways. This episode aims to clarify what inflammation is, how it relates to diet and health, and whether specific foods truly provoke inflammatory responses in the body. The episode provides a nuanced, evidence-based look at inflammation and diet. It explains the difference between acute and chronic inflammation, outlines the role of chronic low-grade inflammation in disease, and emphasizes that overall dietary patterns – rather than any single food – are what influence our inflammatory status. Commonly demonized foods (such as sugar, wheat, and dairy) are scrutinized, and the conversation debunks myths about them being uniformly “inflammatory.” In this episode, Danny takes a look at what the scientific evidence actually shows about anti-inflammatory diets. Note: This is a Premium-exclusive episode. Timestamps 01:06 Understanding Inflammation: Basics and Biomarkers 04:02 Acute vs. Chronic Inflammation 14:21 Biomarkers of Inflammation 22:51 Dietary Patterns and Inflammation 34:53 Specific Foods and Nutrients Impacting Inflammation 47:01 Practical Takeaways for an Anti-Inflammatory Diet 51:30 Conclusion Related Resources Subscribe to Sigma Nutrition Premium Enroll in the next cohort of our Applied Nutrition Literacy course Related podcast episodes: 329: Diet & Inflammation 353: James Hébert, ScD – Dietary Inflammatory Index Sigma Statement: Nutrition & Immune Function The Dietary Inflammatory Index (DII) – Hébert et al., 2019

Talk Ten Tuesdays
Could Physician Advisors Become Dinosaurs?

Talk Ten Tuesdays

Play Episode Listen Later Jun 17, 2025 31:09


Could physician advisors become dinosaurs in healthcare, bound for extinction?The role of the physician advisor has developed into an absolute necessity in hospitals of all sizes around the country. As the healthcare landscape rapidly evolves, physician advisors have served as critical players, bridging the gap between confusion and clarity within clinical and administrative functions.Yet, the question remains unanswered: why are only a fraction of physician advisors employed as full-time employees?During the next live edition of Talk Ten Tuesdays, Juliet B. Ugarte Hopkins, MD, Medical Director of Phoenix Medical Management, Inc., will report on the pitfalls of inadvertently diluting the physician advisor's focus and level of expertise.The popular Internet broadcast will feature the additional following instantly recognizable panelists, who will report more news during their segments:• CDI Report: Cheryl Ericson, Director of clinical documentation integrity (CDI) for the vaunted Brundage Group, will have the latest CDI updates;• The Coding Report: Christine Geiger, Assistant Vice President of Acute and Post-Acute Coding Services for First Class Solutions, will report on the latest coding news;• Field Report: Dennis Jones, a veteran Monitor Mondays and Talk Ten Tuesdays contributing editor, will report on the latest developments regarding the revenue cycle. Jones is the senior director of revenue cycle at Jefferson Health;• News Desk: Timothy Powell, ICD10monitor national correspondent, will anchor the Talk Ten Tuesdays News Desk; and• Point of View: Dr. Kennedy will report on his efforts to advocate for a change in the definition of sepsis. Dr. Kennedy will be sitting in for Angela Comfort, who continues as the co-host for the long-running and popular weekly Internet broadcast.

Clare FM - Podcasts
"New Emergency Department And 600 More Acute Beds Needed In MidWest By 2040"

Clare FM - Podcasts

Play Episode Listen Later Jun 17, 2025 7:50


A new report says the MidWest will need another emergency department and 600 more acute hospital beds by 2040 to meet the demands of the growing population. It comes as The Friends of Ennis Hospital has published its latest research document covering hospital bed capacity projects for the next fifteen years. The group has recommended that a new hospital is built on a new campus and has also poured cold water on HSE plans to build a second 96 bed block at University Hospital Limerick, citing planning obstacles. Chairperson Angela Coll believes a Clare facility is the only viable solution.

Eco-Business Podcast
‘Listen to ecologists – don't bury nature under cement': Hong Kong faces acute biodiversity loss as megaprojects loom

Eco-Business Podcast

Play Episode Listen Later Jun 17, 2025 33:13


The EB Podcast spoke to Dr Bosco Chan, WWF Hong Kong's head of conservation, and Dr Stephan Gale, head of flora conservation at Kadoorie Farm and Botanic Garden, about threats to Hong Kong's unique biodiversity from mega-projects. We discussed: Conservation with Dr Bosco Chan The state of Hong Kong biodiversity: reasons for concern The Northern Metropolis development – what will it mean for Hong Kong's wildlife? How can developers reduce the impact on wildlife? Do cityfolk living in Hong kong or Singapore care about species loss? Models to follow in biophilic city design Conservation with Dr Stephan Gale The climate implications of Hong Kong's mega-projects Why nature restoration matters Nature-sensitive building design The importance native plant species matter to Hong Kong and Singapore "Listen to ecologists"

AFP: American Family Physician Podcast
Episode 231 -- June 2025 -- Part 1 AFP: American Family Physician

AFP: American Family Physician Podcast

Play Episode Listen Later Jun 16, 2025 23:05


Acute monoarthritis (1:30), improving adverse drug reaction reporting (6:30), inappropriate use of oral antiplatelet drugs (9:50), long-term opioid therapy (12:40), treating Clostridioides difficile infection (17:10), and lecanemab for Alzheimer disease (19:00).

Back2Basketball
Why Your Back Pain Keeps Coming Back (Even When You're 'Being Careful')" – Real Talk & Live Q&A

Back2Basketball

Play Episode Listen Later Jun 16, 2025 32:35


RCP Medicine Podcast
Episode 84: IBD - Ulcerative colitis (part 1)

RCP Medicine Podcast

Play Episode Listen Later Jun 13, 2025 23:44


In this episode of the RCP Medicine podcast, Professor Ailsa Hart and Dr Eathar Shakweh discuss how to approach managing Inflammatory Bowel Disease (IBD) in the acute medical setting. This is the first episode of a 2-part series, with a focus on ulcerative colitis.  IBD is a common condition, affecting 1 in 123 people in the UK. The 2024 State of the IBD Care in the UK report highlighted the urgent need to shorten time to diagnosis and initiate early treatment to minimise the risk of IBD-related complications. Acute and general medicine physicians have an important role to play in diagnosing and managing IBD. This podcast will equip medics at all stages of training with the necessary knowledge to approach this heterogenous and complex condition. Professor Hart is Director of IBD Research at St Mark's Hospital, London, United Kingdom and a world-leading expert in IBD. Eathar is an IBD Clinical Research Fellow at St Mark's and Imperial, with a special interest in perianal fistulising Crohn's disease. Crohn's & Colitis UK (CCUK) Websitehttps://crohnsandcolitis.org.uk/This is a valuable resource for patients and healthcare professionals alike, containing a wealth of information on IBD investigation and management.British Society of Gastroenterology (BSG) guidelines on Inflammatory Bowel Disease (IBD) - 2019Lamb, Christopher Andrew et al. “British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults.” Gut vol. 68,Suppl 3 (2019): s1-s106. doi:10.1136/gutjnl-2019-318484https://pubmed.ncbi.nlm.nih.gov/31562236/For interested listeners, these are the national guidelines for IBD diagnosis and management. Please note, the new guidelines for 2025 are pending release.RCP LinksEducation and learning | RCP Events | RCP Membership | RCP Improving care | RCP Policy and campaigns | RCP CreditsMusic by bensound.com

VetFolio - Veterinary Practice Management and Continuing Education Podcasts
Dietary Intervention for GI Conditions – from Acute to Chronic

VetFolio - Veterinary Practice Management and Continuing Education Podcasts

Play Episode Listen Later Jun 12, 2025 42:04


Tune in to this engaging VetFolio Voice podcast episode with host Dr. Cassi and her guest, Dr. Alison Manchester, to learn about clinically relevant information applicable to dietary management of GI upset, including recent updates—from clinical research to real-life cases—that are commonly seen in practice. The conversation encompasses a review of different dietary strategies, including their potential mechanisms of action. Special attention will be paid to the impact of diet and other interventions on the gut microbiome. You'll also explore the differences in dietary interventions for dogs and cats and get tips for client communication tactics that help maximize compliance.

Hard to Believe
#051 – Acute Religious Experiences - with Richard Saville-Smith

Hard to Believe

Play Episode Listen Later Jun 10, 2025 59:18


This week, Richard Saville-Smith joins Kelly and John to talk about his book Acute Religious Experiences – Madness, Psychosis, and Religious Studies, which was published by Bloomsbury in 2023. Saville-Smith is an independent researcher who focuses on the intersection of madness, mental disorders, and acute religious experiences, from a mad studies perspective. He earned his PhD in Philosophy and Religious Studies from the University of Edinburgh in 2020. They discuss the relatively little-known academic field of mad studies - which seeks to destigmatize and depathologize the concept of madness - and how the fields of psychiatry and religious studies, often operating in conflict with one another, have distorted our understanding of the authenticity of acute religious experiences like the ones described in the lives of Joan of Arc or Jesus. Richard is on Bluesky @dranamorphosis

Talk Ten Tuesdays
Five Key Takeaways from CHIA

Talk Ten Tuesdays

Play Episode Listen Later Jun 10, 2025 34:55


One of the largest regional coding organizations in America's healthcare universe – the California Health Information Association (CHIA) – wrapped its final workshops this past week, with delegates flying home to share their insights on what was considered to be a pivotal experience.The ICD10monitor producers of Talk Ten Tuesdays have secured a rare appearance of CHIA's past president, Gloryanne Byrant, who agreed to share five key takeaways from the annual conference.During the next live edition of Talk Ten Tuesdays, coming up at 10 a.m. EST on June 10, the popular Internet broadcast will feature the additional following instantly recognizable panelists, who will report more news during their segments:• CDI Report: Cheryl Ericson, Director of CDI for the vaunted Brundage Group, will have the latest CDI updates;• Field Report: Dennis Jones, a veteran Monitor Mondays and Talk Ten Tuesdays contributing editor, will report on the latest developments regarding the revenue cycle. Jones is the administrator of the revenue cycle at Jefferson Health;The Coding Report: Christine Geiger, Assistant Vice President of Acute and Post-Acute Coding Services for First Class Solutions, will report on the latest coding news;• News Desk: Timothy Powell, ICD10monitor national correspondent, will anchor the Talk Ten Tuesdays News Desk; and• MyTalk: Angela Comfort, veteran healthcare subject-matter expert, will co-host the long-running and popular weekly Internet broadcast. Comfort is the Assistant Vice President of Revenue Integrity for Montefiore Health.

JACC Speciality Journals
Current Practice of Guideline-Directed Medical Therapy After Acute Heart Failure Hospitalization: A Nationwide Observational Study | JACC: Asia

JACC Speciality Journals

Play Episode Listen Later Jun 10, 2025 2:51


JACC Speciality Journals
Brief Introduction - Current Practice of Guideline-Directed Medical Therapy After Acute Heart Failure Hospitalization: A Nationwide Observational Study | JACC: Asia

JACC Speciality Journals

Play Episode Listen Later Jun 10, 2025 1:52


Black Sheep Chiropractic Podcast
Most Chiropractic Marketing Takes Time

Black Sheep Chiropractic Podcast

Play Episode Listen Later Jun 9, 2025 19:25 Transcription Available


In this episode of the Rocket Chiro Podcast, Jerry Kennedy explores how different age groups engage with brands online—and what that means for your chiropractic marketing. Using a recent infographic from NP Digital as a jumping-off point, Jerry breaks down why Gen Z takes longer to follow brands on social media, why Boomers tend to move quicker, and how your marketing strategy should align with your goals, target demographic, and level of urgency. Whether you're doing content marketing, social ads, SEO, or community outreach, understanding your audience's behavior is crucial. Jerry also shares actionable strategies based on patient intent—like how to attract people looking for acute care now versus those slowly building trust over time. Key Takeaways 1. Different Generations = Different Timelines Gen Z needs an average of 11 exposures before following a brand. Millennials and Gen X fall in the 6–7 range—similar to long-standing marketing wisdom. Boomers need only 3 exposures on average. The more content someone consumes, the more desensitized they become—especially Gen Z. 2. Trust and Time in Marketing Most people don't take action the first time they see you unless they're in a crisis or acute pain. Content overload and algorithm filters mean you're competing with everything—not just other chiropractors. Patience is essential in relationship-based marketing. 3. Match Your Marketing to Your Intentions If you need patients today, prioritize: Acute care marketing SEO and Google Ads Networking with professionals If you're building a long-term brand, focus on: Content marketing (blogs, videos, podcasting, community involvement) Authority building (testimonials, reviews, collaborations) Social media presence (but know it takes time!) 4. Tailor Your Tactics by Demographic Older patients: Use Facebook, email, direct mail, print, TV, radio. Younger patients: Use Instagram, TikTok, YouTube Shorts, influencer collaborations. 5. Don't Fish in the Wrong Pond Align your: Target audience Marketing platform Message and tone Budget and expectations Actionable Tips for Chiropractors Need patients fast? Prioritize acute care, SEO, and local Google Ads. Targeting Gen Z or Millennials? Use short-form content, influencer partnerships, and be consistent with social media. Want trust over time? Focus on storytelling, authority, and being visible both online and offline. Don't fake it. Be genuine and let your personality come through in your content. Adapt. Stay aware of platform changes and be ready to evolve your strategy. Final Thoughts “Marketing isn't magic—it's a process. And if you're marketing to people who take longer to trust you, you have to be patient, intentional, and consistent. If your expectations and execution don't match, you're just wasting time and money.” Work With Jerry Want help with your website, SEO, or want to get unstuck in your practice? Visit RocketChiro.com and request a Free New Patient Search Review or explore the Next Step Program for on-demand chiropractic coaching. Want Help Growing Your Practice? Jerry offers business coaching, website design, SEO, and Google Ads services specifically for chiropractors. If you're ready for less stress and more momentum, visit RocketChiro.com. Free New Patient Search Review: https://rocketchiro.com/chiropractic-practice-assessment Best chiropractic websites: https://rocketchiro.com/best-chiropractic-websites Chiropractic SEO: https://rocketchiro.com/chiropractic-seo Coaching for Chiropractors: https://rocketchiro.com/join

The ACDIS Podcast: Talking CDI
Advisory Board series: Acute skin failure

The ACDIS Podcast: Talking CDI

Play Episode Listen Later Jun 4, 2025 26:45


Today's guests are Keisha Downes, MBA-HM, BSN, RN, CCDS, CCS, the vice president of middle revenue cycle for Beth Israel Lahey Health, based in Massachusetts, and Okemena Ewoterai, RN, BSN, MA, CCDS, CDIP, CCS, the director of CDI at Montefiore Medical Center in Bronx, New York. Today's show is part of the “Conversations with Karla” series, hosted by ACDIS Editorial Manager, Products and Events, Karla Kozak, and is part of the occasional series featuring members of the ACDIS Advisory Board. Our intro and outro music for the ACDIS Podcast is “medianoche” by Dee Yan-Kay and our ad music is “Take Me Higher” by Jahzzar, both obtained from the Free Music Archive. Have questions about today's show or ideas for a future episode? Contact the ACDIS team at info@acdis.org. Want to submit a question for a future "listener questions" episode? Fill out this brief form!  CEU info: Each ACDIS Podcast episode now offers 0.5 ACDIS CEU which can be used toward recertifying your CCDS or CCDS-O credential for those who listen to the show in the first two days from the time of publication. To receive your 0.5 CEU, go to the show page on acdis.org, by clicking on the “ACDIS Podcast” link located under the “Free Resources” tab. To take the evaluation, click the most recent episode from the list on the podcast homepage, view the podcast recording at the bottom of that show page, and click the live link at the very end after the music has ended. Your certificate will be automatically emailed to you upon submitting the brief evaluation. (Note: If you are listening via a podcast app, click this link to go directly to the show page on acdis.org: https://acdis.org/acdis-podcast/advisory-board-series-acute-skin-failure) Note: To ensure your certificate reaches you and does not get trapped in your organization's spam filters, please use a personal email address when completing the CEU evaluation form. The cut-off for today's episode CEU is Friday, June 6, at 11:00 p.m. eastern. After that point, the CEU period will close, and you will not be eligible for the 0.5 CEU for this week's episode. Today's sponsor: Today's show is brought to you by Pediatric CDI Foundations, previously titled Pediatric CDI: Building Blocks for Success. Click here to learn more and order your copy today! (https://bit.ly/3PEf7hK) ACDIS update: Apply to speak at the 2026 ACDIS conference by July 21! (https://bit.ly/3Z9zfOf) Get suggestions for session topics at the 2026 ACDIS conference! (https://bit.ly/42WIBiu) Apply to serve on an ACDIS committee by June 30! (https://www.surveymonkey.com/r/June-2025-ACDIS-committees)

Grounded | The Vestibular Podcast
90. Acute Treatments for Vestibular Migraine

Grounded | The Vestibular Podcast

Play Episode Listen Later Jun 3, 2025 11:44 Transcription Available


In this episode, we break down the essential tools and strategies for managing acute Vestibular Migraine attacks. Whether you're newly diagnosed or a seasoned vestibular warrior, understanding your options can make all the difference in navigating sudden flares. We'll cover:

JACC Podcast
ACS Guidelines | MCS in Acute Myocardial Infarction-Cardiogenic Shock | JACC

JACC Podcast

Play Episode Listen Later Jun 3, 2025 11:18


JACC's June 10 issue, focusing on the ACS guideline, features a series of videos with unique perspectives. In this video, JACC: Executive Associate Editor Karthik Murugiah, MBBS, MHS, FACC, introduces his paper discussing the guideline's reliance on four landmark RCTs in AMI-CS. Several sweeping changes in recommendations for MCS use have been codified that should influence practice and improve care for these high-risk patients. While IABP use is expected to decrease, use of mAFP is likely to increase but should be judicious, with caution against overgeneralizing given the narrow selection criteria of DanGer Shock. Evaluating real-world practice patterns and outcomes of patients with AMI-CS based on these recommendations will be paramount.

Talk Ten Tuesdays
Join Us Live from CHIA

Talk Ten Tuesdays

Play Episode Listen Later Jun 3, 2025 29:40


The national conference of the largest regional coding organization chapters in America's healthcare universe gets underway this weekend – and James S. Kennedy, MD, will be there.Dr. Kennedy, president of CDIMD, a national coding and clinical documentation integrity (CDI) consultancy, will be reporting on major events taking place at the California Health Information Association (CHIA) conference, starting this weekend in Southern California.As a longtime editorial contributor to RACmonitor and ICD10monitor, Dr. Kennedy, will be the special guest during the next live edition of Talk Ten Tuesdays, coming up at 10 a.m. EST on June 3. The Internet broadcast, produced by ICD10monitor, is expected to feature the additional following instantly recognizable panelists, who will report more news during their segments:•Social Determinants of Health: Tiffany Ferguson, CEO for Phoenix Medical Management, Inc., will report on the news that is happening at the intersection of medical record auditing and the SDoH;•CDI Report: Cheryl Ericson, Director of CDI for the vaunted Brundage Group, will have the latest CDI updates;•The Coding Report: Christine Geiger, Assistant Vice President of Acute and Post-Acute Coding Services for First Class Solutions, will report on the latest coding news;•News Desk: Timothy Powell, ICD10monitor national correspondent, will anchor the Talk Ten Tuesdays News Desk; and•MyTalk: Angela Comfort, veteran healthcare subject-matter expert, will co-host the long-running and popular weekly Internet broadcast. Comfort is the Assistant Vice President of Revenue Integrity for Montefiore Health.

The Elective Rotation: A Critical Care Hospital Pharmacy Podcast
1031: How Long Does it Take for IM Medications to Work in Acute Agitation?

The Elective Rotation: A Critical Care Hospital Pharmacy Podcast

Play Episode Listen Later Jun 2, 2025 5:48


Show notes at pharmacyjoe.com/episode1031. In this episode, I'll discuss expectations for the onset of action of IM medications used for acute agitation. The post 1031: How Long Does it Take for IM Medications to Work in Acute Agitation? appeared first on Pharmacy Joe.

Antioch Presbyterian Church Sermon of the Week
"Acute Affliction" (Exodus 5:1 – 6:13) - Pastor Zachary Groff

Antioch Presbyterian Church Sermon of the Week

Play Episode Listen Later Jun 1, 2025 45:00


This sermon was preached on June 1, 2025 at Antioch Presbyterian Church, a congregation of Calvary Presbytery of the Presbyterian Church in America located in Woodruff, South Carolina. Pastor Zachary Groff preached this sermon entitled "Acute Affliction" on Exodus 5:1 – 6:13. For more information about Antioch Presbyterian Church, please visit ⁠antiochpca.com⁠ or contact us at ⁠⁠info@antiochpca.com.

The Medbullets Step 2 & 3 Podcast
Gastrointestinal | Acute Hepatitis

The Medbullets Step 2 & 3 Podcast

Play Episode Listen Later May 29, 2025 13:20


In this episode, we review the high-yield topic Acute Hepatitis ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠from the Gastrointestinal section at ⁠⁠⁠⁠Medbullets.com⁠⁠⁠⁠⁠⁠Follow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbulletsLinkedin: https://www.linkedin.com/company/medbullets

The Lead Podcast presented by Heart Rhythm Society
The Lead Podcast - Episode 105: A Discussion of...Acute Results of the Volt-AF IDE Trial...

The Lead Podcast presented by Heart Rhythm Society

Play Episode Listen Later May 29, 2025 17:47


Michael S. Lloyd, MD, FHRS, Emory University is joined by Edward P. Gerstenfeld, MD, MS, FHRS, University of California, San Francisco, and Christopher C Cheung, MD, MPH, FHRS, Sunnybrook HSC, University of Toronto, to discuss the VOLT-AF IDE study evaluated the safety and effectiveness of a novel balloon-based pulsed field ablation (PFA) catheter system for treating paroxysmal and persistent atrial fibrillation (PAF and PsAF). Conducted at 34 global sites, the study enrolled 394 subjects, with 320 included in the primary analysis. Acute pulmonary vein isolation (PVI) success was achieved in over 99% of veins, and primary serious adverse events occurred in only 1.9% of patients, with no significant complications like esophageal injury or hemolysis. Procedure metrics showed efficient operation times, and early 6-month data suggest promising effectiveness. These initial findings support the Volt™ PFA system as a safe and effective treatment option for AF.    https://www.hrsonline.org/education/TheLead https://www.heartrhythmjournal.com/article/S1547-5271(25)02168-X/fulltext Host Disclosure(s): M. Lloyd: Honoraria/Speaking/Consulting: Medtronic, Arga Medtech, Circa Scientific Membership on Advisory Committees: Boston Scientific Contributor Disclosure(s):   E. Gerstenfeld: Honoraria/Speaking/Consulting: Medtronic, Boston Scientific, Biosense Webster, Abbott, Varian Medical Systems, Biotronik Other Non-Financial Relationships: Farapulse, Adagio Medical, Boston Scientific, Abbott Medical, Research (Contracted Grants for PIs and Named Investigators only): Abbott Medical Officer, Trustee, Director, Committee Chair, or Any Other Fiduciary Role: American College of Cardiology Foundation C. Cheung: Nothing to disclose.

Cardiology Trials
Review of the ATLAS trial

Cardiology Trials

Play Episode Listen Later May 27, 2025 9:22


Circulation 1999;100:2312-2318Background: The CONSENSUS and SOLVD trials established the effectiveness of angiotensin converting enzyme inhibitors (ACEi) in reducing mortality and morbidity in patients with systolic heart failure. Both trials used enalapril with a target dose of 20mg twice a day (max dose) in the CONSENSUS trial and 10mg twice a day (medium dose) in the SOLVD trials. In real-world settings, ACEi are sometimes prescribed at lower doses, likely reflecting concerns about adverse effects or patients' tolerance. It was unclear whether the benefit from low doses of ACEi is comparable to high doses.Cardiology Trial's Substack is a reader-supported publication. To receive new posts and support our work, consider becoming a free or paid subscriber.The Assessment of Treatment with Lisinopril and Survival (ATLAS) trial sought to assess the efficacy and safety of low vs high doses of ACE inhibition in patients with systolic heart failure.Patients: Eligible patients had left ventricular ejection fraction of 30% or less and had NYHA class II, III or IV despite treatment with diuretics for two or more months.Patients were excluded if they had any of the following: Acute coronary syndrome or revascularization procedure within 2 months, history of sustained or symptomatic ventricular tachycardia, known intolerance to ACEi, serum creatinine >2.5 mg/dL, or any noncardiac condition that could limit survival.Baseline characteristics: The trial randomized 3,164 patients – 1,596 randomized to the low-dose arm and 1,568 to the high dose arm.The average age of patients was 64 years and 80% were men. The average left ventricular ejection fraction was 23%. Cardiomyopathy was ischemic in 65% of the patients. The NYHA class was II in 16% of the patients, III in 77% and IV in 7%.Data on baseline comorbid conditions were not provided in the main manuscript.Procedures: The study was double blinded. At the beginning of the study, all patients received open-label lisinopril for four weeks to assess who is able to tolerate the drug. Patients who were able to tolerate lisinopril 12.5 mg to15 mg daily for two or more weeks were randomized in a 1:1 ratio to receive low-dose or high-dose ACEi. The target dose of lisinopril in the lose dose group was 2.5 to 5.0mg daily and was 32.5 to 35mg daily in the high dose group.All patients received open-label lisinopril 2.5 to 5mg daily. This dose was selected by the investigator. In addition, patients received up to three 10mg tablets of lisinopril or matching placebo.Endpoints: The primary endpoint was all-cause mortality. Secondary end points included cardiovascular mortality, all-cause hospitalization and cardiovascular hospitalizations.Analysis was performed based on the intention-to-treat principle. The estimated sample size was 3,000 patients. This sample size had 90% power at 5% alpha to detect 15% relative risk difference in the mortality between both treatment groups assuming 19% 1-year mortality in the high dose group.Results: Of the 3,793 patients who entered the initial open-label tolerability phase, 83.4% were randomized. A total of 176/3,793 (4.6%) were withdrawn for possible side effects. The median follow-up time was 46 months.Target doses were achieved in 92.7% of the patients in the low-dose group and 91.3% in the high-dose group. Study medication was discontinued by 30.6% of patients in the low-dose group and 27.2% in the high-dose group.All-cause mortality was not significantly different between both treatment groups (44.9% with low dose vs 42.5% with high dose, HR: 0.92, 95% CI: 0.82 – 1.03; p= 0.128). Cardiovascular mortality was numerically lower in the high dose group but this was not statistically significant (37.2% vs 40.2%, HR: 0.90, 95% CI: 0.81 – 1.01; p= 0.073). All-cause hospitalization was lower in the high dose group (3,819 hospitalizations vs 4,397; p= 0.021). Hospitalizations for cardiac causes and hospitalizations for heart failure were also lower in the high dose group (2,456 vs 2,923; p= 0.05) and (1,199 vs 1,576; p= 0.002), respectively.Patients in the high-dose group experienced more dizziness (19% vs 12%), more hypotension (11% vs 7%), more worsening renal function (10% vs 7%), and more hyperkalemia (6% vs 4%), but reported less cough (11% vs 13%) and had less hypokalemia (1% vs 3%).There were no significant subgroup interactions for the primary outcome.Conclusion: In patients with systolic heart failure, high dose ACE inhibition did not significantly reduce mortality compared to low-dose but it led to significantly less hospitalizations. In this trial of 3,164 patients and with a median follow up of 46 months, there were 578 less hospitalizations in the high dose group.Based on these results, we recommend up-titrating ACEi and use higher doses if tolerated. Although, side effects were more common in the high dose group, these can generally be managed with reducing the dose in the outpatient settings.Cardiology Trial's Substack is a reader-supported publication. To receive new posts and support our work, consider becoming a free or paid subscriber. Get full access to Cardiology Trial's Substack at cardiologytrials.substack.com/subscribe

Epigenetics Podcast
Epigenetic Regulation and Small Molecule Innovation in AML: Advances in Translational Leukemia Research (Ani Deshpande)

Epigenetics Podcast

Play Episode Listen Later May 22, 2025 60:58


In this episode of the Epigenetics Podcast, we talked with Ani Deshpande from Sanford Burnham Prebys about his work on epigenetic regulation and developing small molecules through high throughput screens for AML. Throughout our discussion, we delve into Dr. Despande's journey into the field of biology and science, tracing his evolution from a literature enthusiast in Mumbai to a dedicated cancer researcher. He reflects on his formative experiences during his PhD at Ludwig Maximilian University in Munich, where she developed murine models for refractory acute myeloid leukemia (AML). We examine these models' contributions to therapeutic discovery and understanding the intricate mechanisms underscoring AML's complexities. Transitioning to his postdoctoral work at Scott Armstrong's lab in Boston, Dr. Despande shares his insights on the importance of epigenetic regulators, such as DOT1L, in leukemias, and how they can serve as strategic therapeutic targets. His ambitious pursuit of translational research is further highlighted through his efforts in developing a conditional knockout mouse model and his collaborative work utilizing CRISPR technology to refine our understanding of epigenetic regulation in cancer pathogenesis. Moreover, we engage in a conversation about the challenges and opportunities that arise when establishing his lab at Sanford Burnham Prebys. Dr. Despande candidly discusses the delicate balance between pursuing topics of genuine interest versus adhering to grant fundability, underlining the tension researchers face in the current scientific landscape. His emphasis on the critical need for innovation within lab settings serves as a motivational call for emerging scientists to venture beyond the established templates that often inhibit groundbreaking discoveries. We conclude our dialogue with an exploration of his recent projects, which involve targeting specific epigenetic modifiers and how his lab's findings can contribute to greater understanding and potential treatments for not only AML but also other pediatric cancers driven by gene fusions. Dr. Despande's insights into the integration of modern technologies, such as CRISPR libraries, exemplify his commitment to pushing the boundaries of cancer research. In addition to discussing his scientific contributions, we touch upon Dr. Despande's foray into podcasting (The Discovery Dialogues), shedding light on his motivation to bridge the communication gap between scientists and the broader public. He articulates his desire to demystify scientific discoveries and promote awareness about the intricate journey of research that lays the groundwork for medical advancements. This multidimensional discussion not only highlights his scientific achievements but also emphasizes the importance of effective science communication in fostering public understanding and appreciation of research.   References Deshpande AJ, Cusan M, Rawat VP, Reuter H, Krause A, Pott C, Quintanilla-Martinez L, Kakadia P, Kuchenbauer F, Ahmed F, Delabesse E, Hahn M, Lichter P, Kneba M, Hiddemann W, Macintyre E, Mecucci C, Ludwig WD, Humphries RK, Bohlander SK, Feuring-Buske M, Buske C. Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia. Cancer Cell. 2006 Nov;10(5):363-74. doi: 10.1016/j.ccr.2006.08.023. PMID: 17097559. Deshpande AJ, Deshpande A, Sinha AU, Chen L, Chang J, Cihan A, Fazio M, Chen CW, Zhu N, Koche R, Dzhekieva L, Ibáñez G, Dias S, Banka D, Krivtsov A, Luo M, Roeder RG, Bradner JE, Bernt KM, Armstrong SA. AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes. Cancer Cell. 2014 Dec 8;26(6):896-908. doi: 10.1016/j.ccell.2014.10.009. Epub 2014 Nov 20. PMID: 25464900; PMCID: PMC4291116. Sinha S, Barbosa K, Cheng K, Leiserson MDM, Jain P, Deshpande A, Wilson DM 3rd, Ryan BM, Luo J, Ronai ZA, Lee JS, Deshpande AJ, Ruppin E. A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing. Nat Commun. 2021 Nov 11;12(1):6512. doi: 10.1038/s41467-021-26788-6. Erratum in: Nat Commun. 2022 May 16;13(1):2828. doi: 10.1038/s41467-022-30475-5. PMID: 34764240; PMCID: PMC8586238.   Related Episodes Targeting COMPASS to Cure Childhood Leukemia (Ali Shilatifard) The Menin-MLL Complex and Small Molecule Inhibitors (Yadira Soto-Feliciano) MLL Proteins in Mixed-Lineage Leukemia (Yali Dou)   Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com

The Orthobullets Podcast
Coinflips⎪Recon⎪Acute Hip Pain s/p Bilateral THA in 79M

The Orthobullets Podcast

Play Episode Listen Later May 19, 2025 65:10


Welcome to Season 2 of the Orthobullets Podcast. Today's show is Coinflips, where expert speakers discuss grey zone decisions in orthopedic surgery. This episode will feature doctors Jonathan Yerasimides, Neil Sheth, & Aldo Riesgo. They will discuss the case titled "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Acute Hip Pain s/p Bilateral THA in 79M⁠.⁠⁠⁠⁠⁠⁠" Follow ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Orthobullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on Social Media:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Linkedln⁠

Think Out Loud
Oregon reports record number of student vaccination opt-outs

Think Out Loud

Play Episode Listen Later May 19, 2025 19:49


Oregon kindergarteners are opting out of vaccinations at increasingly higher rates over the last four years. And public health officials are growing increasingly concerned. Oregon is one of just 15 states that allow parents to opt out of childhood vaccinations for nonreligious, nonmedical reasons. The current opt-out rate of 9.7% is the highest recorded in state history. Health officials say the measles and pertussis outbreaks in the state are an indication more work is needed to boost vaccination rates more broadly.We get more details from Stacy de Assis Matthews, the immunization coordinator at Oregon Health Authority, and Dr. Paul Cieslak, medical director for the Acute and Communicable Disease Prevention Section and the Oregon Immunization Program at OHA.      

Sexy Marriage Radio
Understanding Our Functioning Is The Key To A Better Marriage #727

Sexy Marriage Radio

Play Episode Listen Later May 7, 2025 32:19


In this episode of Sexy Marriage Radio, we explore the complexities of relationships, focusing on the concept of regressions and how they affect emotional functioning. We discuss the different types of regressions, the impact of stress, and the contagious nature of regression in relationships. Our conversation emphasizes the importance of self-awareness and understanding one's emotional state to improve relationship dynamics. Takeaways Understanding regressions can empower individuals in relationships. Acute regressions are short-lived but impactful. Steady state regressions can go unnoticed and affect daily functioning. Stressful life events can trigger regressions. Recognizing triggers is crucial for managing regressions. The emotional state of one partner can influence the other. Communication is key to navigating regressions in relationships. Self-awareness helps in identifying personal regressions. High meaning situations can exacerbate emotional challenges. Assuming one is regressed until proven otherwise can lead to better self-management. Enjoy the show! On the Xtended version … In the XTD, we described what regressions look like - now we cover what you can do about them. Join us to find our. Sponsors … Everylove Intimates: Add spice and connection to your marriage with a Date Box. Get 20% off with our code SMR at https://everyloveintimates.com/smr Academy: Join the Academy and go deep The post Understanding Our Functioning Is The Key To A Better Marriage #727 first appeared on Sexy Marriage Radio.