Podcasts about clinical outcomes

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Play Episode Listen Later Apr 9, 2025 12:36

Dr. Emile Daoud, Deputy Editor of JACC Clinical Electrophysiology discusses Characterization and Clinical Outcomes of High-Risk Device-Related Thrombus in the Amulet IDE Trial.

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Transforming Clinical Outcomes With Early Treatment of Lysosomal Disorders

Rare Disease Discussions

Play Episode Listen Later Apr 4, 2025 60:10

This CME program provides information on best practices to manage children with lysosomal disorders who have been identified by newborn screening. WIth the wide range of symptoms and severities that present for these rare conditions, it is not always certain when the best time to start treatment is in these patients.Continuing Education InformationThis continuing education activity is provided by AffinityCE and the Lysosomal and Rare Disorders Research and Treatment Center (LDRTC). This activity provides continuing education credit for physicians. A statement of participation is available to other attendees.To obtain credit, visit https://checkrare.com/learning/p-transforming-clinical-outcomes-with-early-treatment-of-lysosomal-disorders/ Faculty and DisclosuresAffinityCE staff, LDRTC staff, planners, and reviewers, have no relevant financial relationships with ineligible companies to disclose. Faculty disclosures, listed below, will also be disclosed at the beginning of the Program.Ozlem Goker-Alpan MDFounder and CMO, Lysosomal & Rare Disorders Research & Treatment CentersDr. Goker-Alpan is on the Advisory Board/Consultant for Chiesi, Takeda, Sanofi, Prevail/Lilly, Sparks Therapeutics, Uniqure, Exegenesis, Astellas, Freeline, Team Sanfilippo. She receives grants/research support from Chiesi, Sanofi, Takeda, Prevail/Lilly, Spark Therapeutics, Amicus, Freeline, Sangamo, Cyclo, Odorsia, DMT, Homology, Protaliz. She is on the speaker bureau for Sanofi, Takeda, Amicus, ChiesiDavid F. Kronn MDAssociate Professor of Pathology and Pediatrics New York Medical CollegeDr. Kronn is on the Advisory Board for Sanofi. He is also on the speaker bureau for Sanofi. He receives research funding from Sanofi.Uma Ramaswami FRCPCH, MDRoyal Free London Hospitals & Genetics and Genomic Medicine, University College LondonDr. Ramaswami is on the Advisory Board for Amicus, Chiesi, Sanofi and Takeda. She receives research grants from Chiesi and Intabio.Liz Jalazo MDAssistant Professor of Pediatrics and GeneticsUniversity of North Carolina at Chapel HillDr. Jalazo is on the Advisory Board for Sanofi and Ionis. Lindsay Torrice MSN, CPNP-PC MDAssistant Professor of PediatricsUniversity of North Carolina at Chapel HillMs. Torrice has no financial relationships to disclose.Mitigation of Relevant Financial RelationshipsAffinityCE adheres to the ACCME's Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CME activity, including faculty, planners, reviewers, or others, are required to disclose all relevant financial relationships with ineligible companies. All relevant financial relationships for faculty were mitigated by the peer review of content by non-conflicted reviewers before the commencement of the activity.Learning ObjectivesAt the end of this activity, participants should be able to:• Cite the importance of early diagnosis and treatment of lysosomal storage disorders• List the guidelines for the early treatment of LDs and enhanced integration of newborn screening programs• Identify key research gaps and priorities and strengthen collaboration among researchers and healthcare professionals• List the educational resources and support programs for familiesPhysiciansThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of AffinityCE and the LDRTC. AffinityCE is accredited by the ACCME to provide continuing medical education for physicians.AffinityCE designates this enduring activity for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.Other ProfessionalsAll other healthcare professionals completing this continuing education activity will be issued a statement of participation indicating the number of hours of continuing education credit. This may be used for professional education CE credit. Please consult your accrediting organization or licensing board for their acceptance of this CE activity.Commercial SupportThis activity was supported by educational grants from Takeda, Sanofi, and Chiesi.Participation CostsThere is no cost to participate in this activity. CME InquiriesFor all CME policy-related inquiries, please contact us at ce@affinityced.com.Send customer support requests to cds_support+ldrtc@affinityced.com.

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The Beat With Joel Dunning Ep. 99: CT Scan-Negative Type A Dissection

CTSNet To Go

Play Episode Listen Later Apr 3, 2025 47:25

This week on The Beat, CTSNet Editor-in-Chief Joel Dunning speaks with Dr. Salim Aziz, thoracic and cardiovascular surgeon and clinical professor at George Washington University, about computed tomography (CT) scan-negative type A dissection. Chapters 00:00 Intro 00:57 Dr. Aziz Preview 02:01 Bringing International Colleagues to Centers 07:01 Ambulation Protocol ECMO 09:12 COPD Severity, Aortic Aneurysm 11:37 Robotic Mitral Repair Learning Curve 15:43 Ross Procedure in Neonates, Analysis 19:21 Tirone David Keynote 21:52 AVR 101 23:08 Robotic Beating-Heart TECAB: LIMA-LAD 25:17 Dr. Aziz, CT Scan-Negative Type A Dissection 43:52 Closing They discuss Dr. Aziz's experience with cases that present as CT scan-negative, discussing the details of these cases and the concerning frequency with which aortic dissections are overlooked. They also explore routine transesophageal echocardiogram (TEE) in the operating room, finding tears, and aortic aneurysms. Joel also reviews recent JANS articles on the ambulation protocol for adult patients receiving extracorporeal membrane oxygenation, if the severity of chronic obstructive pulmonary disease is associated with adverse outcomes after open thoracoabdominal aortic aneurysm repair, the learning curve of robotic mitral repair, and long-term outcomes following the Ross procedure in neonates and infants. In addition, Joel explores a 2024 London Core Review Cardiothoracic Surgery Course on “Surgical Treatments of Aortic Root Aneurysms,” aortic valve replacement 101 through an upper ministernotomy, and robotic beating-heart totally endoscopic coronary bypass. Before closing, he highlights upcoming events in CT surgery. JANS Items Mentioned 1.) Ambulation Protocol for Adult Patients Receiving Extracorporeal Membrane Oxygenation: A Quality Improvement Initiative 2.) The Severity of Chronic Obstructive Pulmonary Disease Is Associated With Adverse Outcomes After Open Thoracoabdominal Aortic Aneurysm Repair 3.) Learning Curve of Robotic Mitral Repair: Prospective Two-Centre Study of Proficiency and Clinical Outcomes 4.) Long-Term Outcomes Following the Ross Procedure in Neonates and Infants: A Multi-Institutional Analysis CTSNET Content Mentioned 1.) Surgical Treatments of Aortic Root Aneurysms: 2024 London Core Review Cardiothoracic Surgery Course 2.) Aortic Valve Replacement 101 Through an Upper Ministernotomy 3.) Robotic Beating-Heart Totally Endoscopic Coronary Bypass (TECAB): LIMA to LAD Other Items Mentioned 1.) Putative Computed Tomography Scan-Negative Type A Dissection 2.) Webinar Series: Women in Cardiothoracic Surgery—Advancement Through Collaboration 3.) President's Series With Husam Balkhy | ISMICS President 4.) London Core Review Registration 5.) Career Center 6.) CTSNet Events Calendar Disclaimer The information and views presented on CTSNet.org represent the views of the authors and contributors of the material and not of CTSNet. Please review our full disclaimer page here.

Sari Reisner on the benefits of gender-affirming hormone therapy on HIV clinical outcomes

In conversation with...

Play Episode Listen Later Mar 27, 2025 21:28

Sari Reisner (University of Michigan School of Public Health, Boston, USA) on gender-affirming hormone therapy for transgender, non-binary, and gender-diverse people in the US and its effects on HIV acquisition risk and viral suppression.Read the article:https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(25)00004-9/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhivAnd the personal view:https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(24)00299-6/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhivContinue this conversation on social!Follow us today at...https://thelancet.bsky.social/https://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

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Clinical outcomes and electrophysiological characteristics of partial perforation after left bundle branch area pacing | JACC: Clinical Electrophysiology

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Play Episode Listen Later Mar 19, 2025 4:00

Dr. Kenneth Ellenbogen, MD, Deputy Editor of JACC Clinical Electrophysiology, discusses Clinical outcomes and electrophysiological characteristics of partial perforation after left bundle branch area pacing

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Therapeutic Interventions for Autoimmune Retinopathy

Ophthalmology Journal

Play Episode Listen Later Mar 13, 2025 21:01

Dr. Edmund Tsui is joined by Dr. Majda Hadziahmetovic to discuss her meta-analysis and systematic review investigating the effectiveness of systemic and local treatments in slowing autoimmune retinopathy progression. From the Ophthalmology Science article, “Clinical Outcomes of Therapeutic Interventions for Autoimmune Retinopathy: A Meta-analysis and Systematic Review.” Clinical Outcomes of Therapeutic Interventions for Autoimmune Retinopathy: A Meta-analysis and Systematic Review. Kapoor, Ishani et al. Ophthalmology Science, Volume 5, Issue 1. CALL FOR ABSTRACTS! Now accepting paper, poster, and video submissions through April 8. Imagine presenting at AAO 2025; learn more and submit yours at aao.org/pod25

Long-Term Clinical Outcomes After IFR- vs FFR-Guided Coronary Revascularization: Insights From the SWEDEHEART National Registry | JACC: Cardiovascular Interventions

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Play Episode Listen Later Mar 4, 2025 6:53

Abdullah Al-Abcha, MD, social media editor of JACC: Cardiovascular Interventions, and Matthias Götberg, MD, PhD, discuss a recently published manuscript reporting the long-term clinical outcomes after IFR vs. FFR guided coronary revascularization— Insights from SWEDEHEART.

Clonal Hematopoiesis Is Associated With Adverse Clinical Outcomes and Left Ventricular Remodeling in Aortic Stenosis - JACC: Advances

The Shoulder Physio Podcast

Play Episode Listen Later Feb 26, 2025 2:29

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Clonal Hematopoiesis Is Associated With Adverse Clinical Outcomes and Left Ventricular Remodeling in Aortic Stenosis

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#44 Finishing my PhD: Reflections and Tips with Jared Powell, PhD

Play Episode Listen Later Feb 25, 2025 45:02

In this episode of The Shoulder Physio Podcast, I am interviewed by my wife, Tara, about my recently completed PhD. For the past 7 years of my life I have been engaged in a research based PhD investigating the causal mechanisms underpinning the effectiveness of exercise therapy for rotator cuff related shoulder pain. This research program has produced 6 published pieces of research that is contained with the thesis. In this episode I briefly discuss the premise of the thesis, its main findings, and recommendations for future research. I also gives some tips and tricks and to prospective PhD or current PhD students which may help their journey. Don't miss this episode with myself, Dr Jared Powell, and my wife, the amazing Tara Powell. Buckle up! Key Papers: Powell JK, Lewis JS. Rotator Cuff-Related Shoulder Pain: Is It Time to Reframe the Advice, "You Need to Strengthen Your Shoulder"? J Orthop Sports Phys Ther. 2021 Apr;51(4):156-158. doi: 10.2519/jospt.2021.10199. PMID: 33789431. Powell JK, Schram B, Lewis J, Hing W. "You have (rotator cuff related) shoulder pain, and to treat it, I recommend exercise." A scoping review of the possible mechanisms underpinning exercise therapy. Musculoskelet Sci Pract. 2022 Dec;62:102646. doi: 10.1016/j.msksp.2022.102646. Epub 2022 Aug 8. PMID: 35964499. Powell JK, Schram B, Lewis J, Hing W. Physiotherapists nearly always prescribe exercise for rotator cuff-related shoulder pain; but why? A cross-sectional international survey of physiotherapists. Musculoskeletal Care. 2023 Mar;21(1):253-263. doi: 10.1002/msc.1699. Epub 2022 Sep 11. PMID: 36089802. Powell JK, Costa N, Schram B, Hing W, Lewis J. "Restoring That Faith in My Shoulder": A Qualitative Investigation of How and Why Exercise Therapy Influenced the Clinical Outcomes of Individuals With Rotator Cuff-Related Shoulder Pain. Phys Ther. 2023 Dec 6;103(12):pzad088. doi: 10.1093/ptj/pzad088. PMID: 37440455; PMCID: PMC10733131. Powell JK, Lewis J, Schram B, Hing W. Is exercise therapy the right treatment for rotator cuff-related shoulder pain? Uncertainties, theory, and practice. Musculoskeletal Care. 2024 Jun;22(2):e1879. doi: 10.1002/msc.1879. PMID: 38563603. READ THE WHOLE THESIS! Check out the Shoulder Physio Online Course here Connect with Jared and guests: Jared on Instagram: @‌shoulder_physio Jared on Twitter: @‌jaredpowell12 See our Disclaimer here: The Shoulder Physio - Disclaimer

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Ep. 69 Intradiscal Augmentation and Frontiers in Back Pain Treatment with Dr. Olivier Clerk

BackTable MSK

Play Episode Listen Later Feb 18, 2025 24:49

Vertebral augmentation for degenerative disc disease has traditionally been performed using cement injections. However, new biomaterials are emerging that may offer more precise targeting of the vertebral discs, potentially leading to higher patient satisfaction. In this episode of Backtable MSK, Dr. Olivier Clerk-Lamalice discusses significant advances in the treatment of degenerative disc disease, with a particular focus on disc augmentation using intradiscal hydrogel. This episode marks the third and final installment in our series on degenerative disc disease with Dr. Clerk-Lamalice. --- This podcast is supported by: Medtronic Interventional https://www.medtronic.com/interventional --- SYNPOSIS Dr. Clerk-Lamalice begins by exploring the history of hydrogel use for degenerative disc disease, highlighting the different iterations of this biomaterial. As an experienced practitioner in this field, he shares valuable tips on injection volume and technique. His work is especially meaningful to him because the procedure provides significant pain relief for patients. The doctors also delve into patient selection criteria and ongoing clinical trials aimed at obtaining FDA approval in North America. Additionally, the episode offers a preview of the upcoming GRIBOI conference, which will focus on the use of injectable osteoarticular biomaterials in bone augmentation. --- TIMESTAMPS 00:00 - Introduction 02:28 - History and Current Use of Intradiscal Hydrogel 07:19 - Technical Insights for Injection 12:51 - Clinical Outcomes and Patient Satisfaction 15:33 - Ongoing FDA Clinical Trials 16:38 - Future Research and GRIBOI Conference Details --- RESOURCES BackTable MSK Ep. 67- Introduction to the Treatment of Discogenic Back Pain: https://www.backtable.com/shows/msk/podcasts/67/introduction-to-treatment-of-discogenic-back-pain BackTable MSK Ep. 68- BackTable Basics: Lumbar Access and Discography https://www.backtable.com/shows/msk/podcasts/68/backtable-basics-lumbar-disc-access-discography GRIBOI Conference: https://www.griboi.org/annualconference Hydrogel Augmentation of the Lumbar Intervertebral Disc: An Early Feasibility Study of a Treatment for Discogenic Low Back Pain (Beal et al, 2024): https://www.jvir.org/article/S1051-0443(23)00694-2/fulltext

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JACC: Asia - Brief Introduction - Effect of Renal Impairment on Clinical Outcomes After Mitral Valve Transcatheter Edge-to-Edge Repair

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Play Episode Listen Later Feb 11, 2025 1:51

Commentary by Dr. Jian'an Wang

JACC: Cardiovascular Interventions - Hemodynamic Valve Deterioration After Transcatheter Aortic Valve Replacement: Incidence, Predictors, and Clinical Outcomes

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Play Episode Listen Later Feb 10, 2025 5:37

Abdullah Al-Abcha, MD, social media editor of JACC: Cardiovascular Interventions, and Thomas Pilgrim, MD, MSc, discuss a recently published manuscript reporting the incidence, predictors, and clinical outcomes hemodynamic valve deterioration after transcatheter aortic valve replacement.

Why Mental Health Care Is Failing & What We Can Do About It with Dr. Chris Palmer

Metabolic Mind

Play Episode Listen Later Jan 27, 2025 59:50

Mental health care is at a critical crossroads. Millions of people are searching for effective treatments, yet conventional options often fall short, leaving many without significant or lasting relief. Compounding this issue is the lack of funding directed toward exploring novel, root-cause therapies. The urgency for change is clear. Dr. Chris Palmer, a Harvard psychiatrist and the author of Brain Energy, has been instrumental in raising awareness about the metabolic nature of mental illness. His pioneering work highlights how conditions like depression, bipolar disorder, and schizophrenia often stem from underlying metabolic dysfunctions, including glucose hypometabolism, neurotransmitter imbalances, inflammation, and oxidative stress. In this interview, Dr. Palmer dives into the science behind mental illnesses and shares groundbreaking insights into how ketogenic therapy is changing lives. In this interview, you'll learn: Why the current mental health system struggles to provide effective care How ketogenic therapies and lifestyle changes are reshaping psychiatry The role of mitochondria and metabolism in brain health The urgent need for research on tapering medications safely The current state of mental health research funding and the path towards systemic change Why mental illness should be viewed as a systemic condition, not just a brain disorder This conversation highlights the urgent need for change in psychiatry, how metabolic therapies are offering new hope for those living with mental illness, and the path towards more effective evidence based care and better patient outcomes. Expert Featured: Dr. Chris Palmer X: @ChrisPalmerMD www.ChrisPalmerMD.com Purchase Brain Energy: https://brainenergy.com/#order-window Studies Mentioned Beyond comorbidities: metabolic dysfunction as a root cause of neuropsychiatric disorders https://www.cambridge.org/core/journals/bjpsych-advances/article/abs/beyond-comorbidities-metabolic-dysfunction-as-a-root-cause-of-neuropsychiatric-disorders/9B7489EF96DCA9F41005DD7E61B27023 The Ketogenic Diet as a Transdiagnostic Treatment for Neuropsychiatric Disorders: Mechanisms and Clinical Outcomes https://link.springer.com/article/10.1007/s40501-024-00339-4 CMEs Mentioned Brain Energy: The Metabolic Theory of Mental Illness https://www.mycme.com/courses/brain-energy-the-metabolic-theory-of-mental-illness-9615 Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

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INFINITY-SWEDEHEART Complex PCI: 1-Year Landmark 6–12 Month Clinical Outcomes Among Patients with Complex Lesion Subsets Treated with DynamX Bioadaptor Compared to a Contemporary Drug Eluting Stent

CRTonline Podcast

Play Episode Listen Later Dec 24, 2024 11:03

INFINITY-SWEDEHEART Complex PCI: 1-Year Landmark 6–12 Month Clinical Outcomes Among Patients with Complex Lesion Subsets Treated with DynamX Bioadaptor Compared to a Contemporary Drug Eluting Stent

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Impact of Renal & Liver Function on Clinical Outcomes Following Tricuspid Valve Transcatheter Edge-to-Edge Repair

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Play Episode Listen Later Dec 9, 2024 11:16

In this podcast, Dr. Valentin Fuster discusses a study on the impact of renal and liver function on clinical outcomes following tricuspid valve transcatheter H2O repair in patients with severe tricuspid regurgitation. While the study found no significant differences in organ function between repair and control groups at 12 months, successful repairs showed small but favorable improvements in kidney and liver function, suggesting potential long-term benefits in reducing heart failure hospitalizations and mortality.

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The Beat With Joel Dunning Ep. 81: How to Be a Better Trainer

CTSNet To Go

Play Episode Listen Later Nov 26, 2024 43:07

This week on The Beat, CTSNet Editor-in-Chief Joel Dunning discusses how to be a better trainer. He explores tips for training people, the five levels of training, and sensory overload. Later in the podcast, he further explores the topic of training trainers with Professor Mark Coleman, co-founder of Lapco, an innovative training consultancy focused on safer surgeries. They highlight details of Professor Coleman's courses, the program's learning curve, and how this training could be beneficial for cardiothoracic surgeons worldwide. Joel also reviews recent JANS articles on clinical outcomes of mitral valve surgery in atrial functional mitral regurgitation in the REVEAL-AFMR registry, risk of transfusion in isolated coronary artery bypass graft, the efficacy of loco-regional ropivacaine analgesia via intercostal catheters after lung resection, and percutaneous transcatheter edge-to-edge repair for functional mitral regurgitation in heart failure. In addition, Joel explores a case report of coronary stentectomy, principles of complex mitral valve repair with Leonard Lee and Vince Gaudiani, and uniportal robotic-assisted extended thymectomy. Before closing, he highlights upcoming events in CT surgery. JANS Items Mentioned 1.) Clinical Outcomes of Mitral Valve Surgery in Atrial Functional Mitral Regurgitation in the REVEAL-AFMR Registry 2.) Risk of Transfusion in Isolated Coronary Artery Bypass Graft: Models Developed From The Society of Thoracic Surgeons Database 3.) The Efficacy of Loco-Regional Ropivacaine Analgesia Via Intercostal Catheters After Lung Resection: A Randomized, Double-Blind, Placebo-Controlled, Superiority Study 4.) Percutaneous Transcatheter Edge-to-Edge Repair for Functional Mitral Regurgitation in Heart Failure: A Meta-Analysis of Three RCTs CTSNET Content Mentioned 1.) Undressing the “Full Metal Jacket”—A Case Report of Coronary Stentectomy 2.) Principles of Complex Mitral Valve Repair: An Exploration With Leonard Lee and Vince Gaudiani 3.) Uniportal Robotic-Assisted Extended Thymectomy Other Items Mentioned CTSNet Events Calendar Disclaimer The information and views presented on CTSNet.org represent the views of the authors and contributors of the material and not of CTSNet. Please review our full disclaimer page here.

106: Overtime: SLAP Tear Management - Repair or Tenodesis? (REBOOT)

The Sports Docs Podcast

Play Episode Listen Later Nov 18, 2024 31:24

Welcome to Overtime with the Sports Docs. On each of these mini episodes, Catherine and I chat about a new topic or surgical technique in the field of sports medicine. We'll give you our quick take on the most recent data ranging from operative indications, surgical approaches, post-op protocols and most importantly – patient outcomes.Today we're talking about SLAP tears – tears of the superior labrum from anterior to posterior. We have two great articles for you today that focus on the surgical management of SLAP tears – specifically whether we should be repairing SLAP tears or proceeding directly to biceps tenodesis. We will also discuss the different types of biceps tenodesis procedures – mainly arthroscopic suprapectoral versus open subpectoral.Our first paper looks specifically at this patient population – young overhead athletes – and investigates the functional and athletic outcomes after primary subpectoral biceps tenodesis for type II SLAP tears. Brian Waterman and Tony Romeo published a case series in the January 2023 issue of Arthroscopy titled “High Rate of Return to Sporting Activity Among Overhead Athletes with Subpectoral Biceps Tenodesis for Type II SLAP Tear”. The authors reported that 81% of patients returned to their previous level of play at an average of 4 months post-op. There were also significant improvements in VAS and SANE scores post-op.But how do repairs do in this population? The answer is… not great. Return to preinjury level of play after SLAP repair has been reported in the range of 54% to 63% of elite throwers. In one cohort study by Boileau, 60% of patients reported persistent shoulder pain after SLAP repair and 50% elected to undergo secondary surgery. Provencher published on his outcomes of SLAP repair in an active military population and reported a 37% failure rate and 28% revision rate at short to mid-term follow up.Our second article focuses on this and is titled “No Difference in Clinical Outcomes for Arthroscopic Suprapectoral Versus Open Subpectoral Biceps Tenodesis at Midterm Follow-up.” Nikhil Verma – who will be joining us at AOSSM – and colleagues at Rush compared arthroscopic suprapectoral tenodesis versus open subpectoral tenodesis for long head of biceps tendon disease, so not SLAP tears. They reported no significant differences in patient reported outcomes or complications at any time point.

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AJSM November 2024 5-in-5 Podcast

SAGE Orthopaedics

Play Episode Listen Later Nov 18, 2024 5:15

Five articles from the November 2024 issue summarized in five minutes, with the addition of a brief editorial commentary. The 5-in-5 feature is designed to give readers an overview of articles that may pique their interest and encourage more detailed reading. It may also be used by busy readers who would prefer a brief audio summary in order to select the articles they want to read in full. The featured articles for this month are, “Surgical Predictors of Clinical Outcome 6 Years After Revision ACL Reconstruction,” “Nonoperative Treatment of Isolated Posterior Glenohumeral Instability in an Active Military Population: Effect of Glenoid and Acromial Morphology,” “Survivorship and Outcomes of Meniscal Ramp Lesions Repaired Through a Posteromedial Portal During Anterior Cruciate Ligament Reconstruction: Outcome Study With a Minimum 10-Year Follow-up,” “All-Inside Endoscopic Classic Bröstrom-Gould Technique: Medium-term Results,” and “Characteristics of Lumbar Pars Interarticularis and Pedicle Stress Injuries by Sport in 902 Pediatric and Adolescent Athletes: A Retrospective Study.” Click here to read the articles.

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The Beat With Joel Dunning Ep. 77: The Nuss Procedure

CTSNet To Go

Play Episode Listen Later Nov 1, 2024 26:52

This week on The Beat, CTSNet Editor-in-Chief Joel Dunning had the opportunity to speak with Dr. Donald Nuss about the NUSS procedure at the 24th Annual Congress: Chest Wall International Group and Phoenix Advanced Pectus Course 2024. They discussed how this procedure was created, how it has evolved, and bar stabilization. They also discuss treatments for pectus excavatum and the Ravitch procedure. Joel also reviews recent JANS articles on real-world outcomes of lobectomy, segmentectomy and wedge resection for the treatment of stage C-IA lung carcinoma, branched stented anastomosis frozen elephant trunk repair, selection for transcatheter versus surgical aortic valve replacement and mid-term survival, and treatment patterns and clinical outcomes of patients with resectable non-small cell lung cancer receiving neoadjuvant immunochemotherapy. In addition, Joel explores the Chrysalis technique, updates on Y-incision aortic annular enlargement, and redo mitral valve repair and left ventricular myectomy. Before closing, he shares upcoming events in CT surgery. JANS Items Mentioned 1.) Real-World Outcomes of Lobectomy, Segmentectomy and Wedge Resection for the Treatment of Stage C-IA Lung Carcinoma 2.) Branched Stented Anastomosis Frozen Elephant Trunk Repair: Early Results From a Physician-Sponsored Investigational Device Exemption Study 3.) Selection for Transcatheter Versus Surgical Aortic Valve Replacement and Mid-Term Survival: Results of the AUTHEARTVISIT Study 4.) Treatment Patterns and Clinical Outcomes of Patients With Resectable Non–Small Cell Lung Cancer Receiving Neoadjuvant Immunochemotherapy: A Large-Scale, Multicenter, Real-World Study (NeoR-World) CTSNET Content Mentioned 1.) The Chrysalis Technique: A Unique New Way to Perform an Aortic Root Replacement 2.) Updates on Y-Incision Aortic Annular Enlargement 3.) Redo Mitral Valve Repair and Left Ventricular Myectomy Other Items Mentioned CTSNet Events Calendar Disclaimer The information and views presented on CTSNet.org represent the views of the authors and contributors of the material and not of CTSNet. Please review our full disclaimer page here.

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10-28-24 Dr. Myriam Roby Hennepin Healthcare Health Equity Clinical Outcomes Director talks about Covid-19 continued with new varients with Freddie Bell and Chantel SinGs on the KMOJ Morning Show

KMOJCast

Play Episode Listen Later Oct 29, 2024 10:58

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Can we afford weight-loss drugs for all?

The Money

Play Episode Listen Later Oct 17, 2024 29:04

Obesity and associated health problems cause a significant burden on health systems, but should weight-loss drugs be offered under our PBS just for weight loss? In Britain, there is to be a trial of the weight loss drug Mounjaro, that will also seek to measure the economic impact of those benefits. Britain's Health Minister argues that weight loss drugs will be '"life-changing, help them get back to work and ease the demands on our NHS". Guests:Dr Norman Swan, co-presenter of ABC Radio National's Health Report, and the podcast 'What's That Rash?'Jonathan Karnon, Professor of Health Economics at Flinders UniversityNial Wheate, Pharmaceutical Chemist and Professor of Academic Excellence at Macquarie University And the Albanese Government this week announced a crack down on unfair and excessive card surcharges, promising to get a better deal for Australians and small business. The declining use of cash and the rise of electronic payments means more Australians are getting hit by often hidden surcharges. Guest:Brad Kelly, Co-founder of the Independent Payment Forum

JAMA Critical Care Research at ESICM Congress 2024

JAMA Author Interviews: Covering research in medicine, science, & clinical practice. For physicians, researchers, & clinician

Play Episode Listen Later Oct 9, 2024 15:37

Transfusion strategy for patients with acute brain injury, telehealth care, acute kidney injury after cardiac surgery, and weaning ventilatory support are the topics of 4 trials published in JAMA and presented at the 2024 European Society of Intensive Care Medicine meeting. JAMA Associate Editor Christopher Seymour, MD, MSc, joins Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss. Related Content: Shifting Balance of the Risk-Benefit of Restrictive Transfusion Strategies in Neurocritically Ill Patients—Is Less Still More? Evaluating Complex Technological Innovations in Critical Care—Current Challenges and Future Directions Impact of Adsorptive Blood Purification on Kidney Outcomes Ventilator Weaning Strategies—Managing Interaction Between Randomized Treatments Restrictive vs Liberal Transfusion Strategy in Patients With Acute Brain Injury Effect of Tele-ICU on Clinical Outcomes of Critically Ill Patients Extracorporeal Blood Purification and Acute Kidney Injury in Cardiac Surgery Frequency of Screening and Spontaneous Breathing Trial Techniques

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Episode 80: Transforming Anorexia Recovery: How Healing Trauma Leads to Real Progress

Fly To Freedom: Healing from an eating disorder

Play Episode Listen Later Oct 1, 2024 37:33

Could unresolved trauma be at the root of your eating disorder? Many people with eating disorders may not realize the connection between their behaviors and past trauma. In this episode, I chat with psychologist and author Dr. Giulia Suro about how unaddressed trauma can fuel eating disorders, leaving many struggling with deep-rooted issues while only treating surface-level symptoms. For those on a journey to anorexia recovery, this episode is a must-listen as it uncovers the often-overlooked link between trauma and eating disorders. If you've ever felt like you've been "treating the symptoms" without seeing lasting recovery, this conversation will give you new insights and hope for true healing. Dr. Julia Sorrow, shares her personal experiences working with trauma survivors and explains how trauma-informed care is critical for treating eating disorders effectively. You'll gain these key insights from the episode: How unresolved trauma impacts the nervous system, leading to coping behaviors like eating disorders. Why it's crucial to address trauma alongside eating disorder behaviors for lasting recovery. Practical steps you can take to reframe your relationship with food and self-care while healing from trauma. Ready to begin your own journey toward lasting anorexia recovery? Sign up for our daily mantra emails to stay grounded and receive my free recovery guide today! Dr. Giulia Suro is a psychologist and researcher specializing in the treatment of eating disorders. She is the author of Learning to Thrive, a popular and accessible ACT workbook. Click on the link below to order her book from Amazon. In addition to her outpatient clinical practice in Washington DC, she is the Director of Research and Clinical Outcomes for Monte Nido, a leading eating disorder treatment conglomerate. Her 2019 workbook Learning to Thrive, is highly regarded in the field. She regularly contributes to The Journal of Eating Disorders and European Eating Disorder Review. See below for a piece she recently wrote for Psyche about the link between eating disorders and trauma.https://psyche.co/ideas/the-important-link-between-eating-disorders-and-past-trauma You can visit her website here: http://www.giuliasuro.com Buy Giulia's book - Learn to Thrive from Amazon.co.uk or Amazon.com If this episode resonated with you, take the next step toward freedom—I'm here to help you. For my gold standard 1:1 coaching, reach out to me here: https://juliatrehane.com/begin-your-recovery/ I also offer lots of free resources: sign up to receive daily mantras and my free recovery guide when you join my email community. You can do this here. Follow me on Instagram for lots of helpful tips @juliatrehane Don't forget to follow this podcast and if you enjoyed it, give it a lovely review, as this helps other people benefit from it too!

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JACC: Asia - Jian'an Wang Discusses 1-Year Clinical Outcomes and the Impact of Procedural Configurations in Left Atrial Appendage Occlusion Patients

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Play Episode Listen Later Oct 1, 2024 2:02

In this episode, Jian'an Wang discusses a pivotal study on the long-term outcomes of left atrial appendage occlusion (LAAO) for stroke prevention in patients with non-valvular atrial fibrillation, analyzing data from over 3,000 patients across China. The findings reveal that combining LAAO with ablation significantly reduces ischemic events, highlighting the importance of tailored procedural strategies and anticoagulation regimens to enhance patient care.

JACC: Asia - Yong-Joon Lee Discusses 1-Year Clinical Outcomes and the Impact of Procedural Configurations in Left Atrial Appendage Occlusion Patients

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Play Episode Listen Later Oct 1, 2024 3:24

In this episode, Professor Yong-Joon Lee discusses a significant study on the one-year clinical outcomes of left atrial appendage occlusion (LAAO) using the Watchman device in older patients with non-valvular atrial fibrillation. The findings highlight the procedure's safety and efficacy, revealing that combined LAAO and ablation significantly reduce the risk of thromboembolic events, while also addressing gaps between clinical guidelines and real-world practices.

JAMA Cardiology : Heart Failure Medical Therapy Score and Clinical Outcomes

JAMA Network

Play Episode Listen Later Sep 25, 2024 15:01

Interview with Paul L. Hess, MD, MHS, and Vincenzo B. Polsinelli, MD, authors of Hospital Heart Failure Medical Therapy Score and Associated Clinical Outcomes and Costs. Hosted by James E. Udelson, MD. Related Content: Hospital Heart Failure Medical Therapy Score and Associated Clinical Outcomes and Costs

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Heart Failure Medical Therapy Score and Clinical Outcomes

JAMA Cardiology Author Interviews: Covering research in cardiovascular medicine, science, & clinical practice. For physicians

Play Episode Listen Later Sep 25, 2024 15:01

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TdC 251: Atualizações no tratamento de obesidade

Ta de Clinicagem

Play Episode Listen Later Sep 18, 2024 43:39

Iaaaaaaaaago Jorge, Marcela Belleza e Nathalie Santana conversam sobre as últimas atualizações no tratamento da obesidade em três partes: o que é obesidade controlada? quais são as drogas novas? quais são os efeitos adversos? Use o cupom TDC2024 para assinar o HITT do Medcof e ganhe um cupom de 6 meses gratuitos do Guia TdC! https://hiit.grupomedcof.com.br Referências: 1. Chuang MH, Chen JY, Wang HY, Jiang ZH, Wu VC. Clinical Outcomes of Tirzepatide or GLP-1 Receptor Agonists in Individuals With Type 2 Diabetes. JAMA Netw Open. 2024;7(8):e2427258. Published 2024 Aug 1. doi:10.1001/jamanetworkopen.2024.27258 2. Coutinho W, Halpern B. Pharmacotherapy for obesity: moving towards efficacy improvement. Diabetol Metab Syndr. 2024;16(1):6. Published 2024 Jan 3. doi:10.1186/s13098-023-01233-4 3. Gudzune KA, Kushner RF. Medications for Obesity: A Review. JAMA. Published online July 22, 2024. doi:10.1001/jama.2024.10816 4. Halpern B, Mancini MC, de Melo ME, et al. Proposal of an obesity classification based on weight history: an official document by the Brazilian Society of Endocrinology and Metabolism (SBEM) and the Brazilian Society for the Study of 5. Jastreboff AM, Aronne LJ, Ahmad NN, et al. Tirzepatide Once Weekly for the Treatment of Obesity. N Engl J Med. 2022;387(3):205-216. doi:10.1056/NEJMoa2206038 6. Jastreboff AM, Kaplan LM, Frías JP, et al. Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial. N Engl J Med. 2023;389(6):514-526. doi:10.1056/NEJMoa2301972 7. Li JR, Cao J, Wei J, Geng W. Case Report: Semaglutide-associated depression: a report of two cases. Front Psychiatry. 2023;14:1238353. Published 2023 Aug 29. doi:10.3389/fpsyt.2023.1238353 8. Lincoff AM, Brown-Frandsen K, Colhoun HM, et al. Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes. N Engl J Med. 2023;389(24):2221-2232. doi:10.1056/NEJMoa2307563 9. Obesity and Metabolic Syndrome (ABESO). Arch Endocrinol Metab. 2022;66(2):139-151. doi:10.20945/2359-3997000000465 10. Rodriguez PJ, Goodwin Cartwright BM, Gratzl S, et al. Semaglutide vs Tirzepatide for Weight Loss in Adults With Overweight or Obesity. JAMA Intern Med. Published online July 8, 2024. doi:10.1001/jamainternmed.2024.2525 11. Wang W, Volkow ND, Berger NA, Davis PB, Kaelber DC, Xu R. Associations of semaglutide with incidence and recurrence of alcohol use disorder in real-world population [published correction appears in Nat Commun. 2024 Jun 18;15(1):5177. doi: 10.1038/s41467-024-49655-6]. Nat Commun. 2024;15(1):4548. Published 2024 May 28. doi:10.1038/s41467-024-48780-6 12. Wang W, Volkow ND, Berger NA, Davis PB, Kaelber DC, Xu R. Association of semaglutide with risk of suicidal ideation in a real-world cohort. Nat Med. 2024;30(1):168-176. doi:10.1038/s41591-023-02672-2

JACC: Advances - Blood Biomarkers Predict 10-Year Clinical Outcomes in Adult Patients With Congenital Heart Disease

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Play Episode Listen Later Sep 18, 2024 3:17

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances discusses a recently published original research paper on using blood biomarkers to predict 10-year clinical outcomes in adult patients with Congenital Heart Disease.

Predicting Long-term Clinical Outcomes of Patients with Recurrent Pericarditis

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Play Episode Listen Later Sep 16, 2024 10:04

In the September 24, 2024, issue of JACC, Dr. Abdullah Yashin Yaprak and his team at Cleveland Clinic unveil a groundbreaking risk prediction model for recurrent pericarditis using machine learning. Their study, analyzing data from 365 patients, offers a novel tool to stratify patients based on their likelihood of achieving clinical remission, showcasing the promising intersection of AI and personalized medicine in cardiology.

JACC: Advances - Cardiovascular Disease in Pregnancy: Clinical Outcomes and Cost-Associated Burdens From a National Cohort at Delivery

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Play Episode Listen Later Aug 28, 2024 3:10

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances discusses a recently published original research paper on Cardiovascular Disease in Pregnancy, including Clinical Outcomes and Cost-Associated Burdens from a National Cohort at Delivery

Association of Adverse Clinical Outcomes with Peri-Infarct Ischemia Detected by Stress Cardiac Magnetic Imaging

Play Episode Listen Later Jul 22, 2024 11:08

Audio Commentary by Dr. Valentin Fuster, Emeritus Editor in Chief

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Impact of Anatomical and Viability-guided Completeness of Revascularization on Clinical Outcomes in Ischemic Cardiomyopathy

Protrusive Dental Podcast

Play Episode Listen Later Jul 15, 2024 13:59

Audio Commentary by Dr. Valentin Fuster, Emeritus Editor in Chief

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ven a Small Ground-Glass Component in Stage I Non–Small Cell Lung Cancer Is Associated With Better Prognosis: Is the 8th TNM Edition Outdated for Part-Solid Nodules?

AJR Podcast Series

Play Episode Listen Later Jul 15, 2024 9:45

Xiao Xiao Tong discusses a study examining the impact of a minor (≤10%) GGO component on the prognosis of clinical stage I NSCLC in comparison with pure-solid nodules. ARTICLE TITLE - Minor or (≤ 10%) Ground-Glass Opacity Component in Clinical Stage I Non–Small Cell Lung Cancer: Associations With Pathologic Characteristics and Clinical Outcomes

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Does Air Particle Abrasion ACTUALLY Improve Clinical Outcomes? – PDP190

Play Episode Listen Later Jul 3, 2024 43:22

Air Particle Abrasion! Images of Sandblasted teeth look cool but does it ACTUALLY improve clinical outcomes? What are the indications? When is it genuinely critical to use? More pragmatically, are there any decent alternatives eg. roughening with a bur? Air particle abrasion, a technique used to prepare tooth surfaces for bonding, has sparked considerable debate among professionals. This episode discussed its effectiveness, implications, and best practices with Dr. Veronica Pereira de Lima. https://youtu.be/oTGQBTyuY-k Watch PDP190 on Youtube Protrusive Dental Pearl: Two advantages of slicing off a corner of the rubber dam are: Anterior Dam Stabilization: By flossing the cut piece through the front teeth, it acts as a makeshift wedge, securely fastening the dam in place without the need for traditional wedjet. Simplified Orientation: This technique aids in aligning the rubber dam properly, streamlining the entire setup process for more efficient dental work. Check out ‘Quick and Slick Rubber Dam' online course (on-demand) only available via the Ultimate Education Plan on Protrusive Guidance Highlights of this episode: 00:44 Protrusive Dental Pearl 04:16 Dr. Verônica Pereira de Lima Introduction 07:07 Journey of Dentistry in Brazil 08:34 Academia vs Clinical Practice 09:20 Journey about PhD and Work Surrounding Air Particle Abrasion 11:12 Importance of Air Particle Abrasion to Clinical Dentistry 15:57 Health Concerns Regarding Air Abrasion Particles 18:10 Air Abrasion Contraindication 20:13 Size of the Microns - Clinical Guidelines 22:25 Pragmatic Approaches in Clinical Practice 24:28 Cojet as an Air Abrasion Particle 27:37 Improper Use of Air Abrasion 30:07 Air Abrasion Guidelines Regarding Different Ceramics 31:40 Alternatives to Air Abrasion 33:29 Dr. Veronica's Personal Guidelines - Air Abrasion Protocol and Unit 40:27 Learning with Dr. Veronica Access the CPD quiz either on your browser or by downloading our mobile app. For the full educational experience, our Ultimate Education Plan gives you access to all our courses, webinars, and exclusive monthly content. If you love this episode, be sure to watch Immediate Dentine Sealing Tutorial Part 1 – PDP173

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Battlefield Bacteria: Combating Resistant Pseudomonas Infections-MILITARY MEDICINE Article of the Year. MAJ Mary B. Ford, MD

WarDocs - The Military Medicine Podcast

Play Episode Listen Later Jun 28, 2024 19:41

Join us on War Docs as we welcome Army Physician MAJ Mary Ford, an infectious disease specialist and lead author of the acclaimed Military Medicine Journal's article of the year: Clinical Characteristics and Resistance Patterns of Pseudomonas aeruginosa Isolated From Combat Casualties https://pubmed.ncbi.nlm.nih.gov/34196358/ Listen in as MAJ Ford shares the impactful findings of her team's research on Pseudomonas aeruginosa in combat casualties, a topic of paramount importance to military health. Her personal journey into the infectious disease field, spurred by early curiosities and familial influences, and the progression of her military career make for a captivating story of dedication and passion. In this engaging conversation, we also tackle the critical subject of infection prevention and antimicrobial stewardship in the face of combat trauma. Hear about the vital role of simple measures, like hand hygiene, in combating infections, especially those caused by the antibiotic-resistant Pseudomonas aeruginosa. Discover how MAJ Ford's team utilized the Trauma Infectious Disease Outcomes Study to uncover that approximately 6% of combat trauma patients developed Pseudomonas infections. The implications of these findings are vast, offering significant advancements for clinical outcomes and infection control in military medical settings. Tune in for a deep understanding of how such research continues to shape practices and policies within the Department of Defense. Chapters: (00:02) Infectious Disease in the Military (07:12) Combat Trauma Infections and Pseudomonas Chapter Summaries: (00:02) Infectious Disease in the Military MAJ Mary Ford's research on Pseudomonas aeruginosa in combat casualties and its impact on military health, her personal journey into infectious disease, and the enduring need for ongoing research in the Department of Defense. (07:12) Combat Trauma Infections and Pseudomonas Infection prevention and antimicrobial stewardship are crucial in controlling Pseudomonas infections in combat trauma patients. Take Home Messages: In the context of military medicine, the issue of infections following combat trauma is a significant concern, with Pseudomonas aeruginosa identified as a noteworthy pathogen due to its prevalence in prolonged hospital stays and its intrinsic antibiotic resistance mechanisms. Infection prevention and antimicrobial stewardship are critical components in the management of combat trauma infections. Basic practices such as hand hygiene play a pivotal role in controlling the spread of infections and can have substantial impacts on patient outcomes. Research conducted through the Trauma Infectious Disease Outcomes Study (T-DOS) has revealed that about 6% of combat trauma patients develop Pseudomonas infections, which underscores the importance of understanding and addressing these infections to improve clinical practices and infection control protocols. Combat trauma patients with Pseudomonas infections often experience lengthy hospital stays and intensive care unit admissions, highlighting the need for robust infection prevention strategies in military healthcare settings to reduce the burden of these nosocomial infections. The fight against infections like Pseudomonas aeruginosa in military medicine is an ongoing challenge that requires continuous research and evidence-based practices to ensure the health and readiness of military personnel. Basic infection control measures remain foundational in mitigating infectious threats. Episode Keywords: Military Medicine, Infectious Disease, Pseudomonas aeruginosa, Combat Trauma, Antimicrobial Stewardship, Research, Clinical Practices, Infection Control, Military Health, Nosocomial Pathogen, Antibiotic Resistance, Retrospective Analysis, Prospectively Collected Data, Trauma Infectious Disease Outcomes Study, Clinical Outcomes, Infection Prevention, Military Medical Environments Hashtags: #wardocs #military #medicine #podcast #MilMed #MedEd #MilitaryMedicine, #PseudomonasAeruginosa, #CombatInfections, #InfectiousDiseases, #AntimicrobialStewardship, #WarDocsPodcast, #MilitaryHealthcare, #TraumaInfections, #InfectionPrevention, #ClinicalResearch Honoring the Legacy and Preserving the History of Military Medicine The WarDocs Mission is to honor the legacy, preserve the oral history, and showcase career opportunities, unique expeditionary experiences, and achievements of Military Medicine. We foster patriotism and pride in Who we are, What we do, and, most importantly, How we serve Our Patients, the DoD, and Our Nation. Find out more and join Team WarDocs at https://www.wardocspodcast.com/ Check our list of previous guest episodes at https://www.wardocspodcast.com/our-guests Subscribe and Like our Videos on our YouTube Channel: https://www.youtube.com/@wardocspodcast Listen to the “What We Are For” Episode 47. https://bit.ly/3r87Afm WarDocs- The Military Medicine Podcast is a Non-Profit, Tax-exempt-501(c)(3) Veteran Run Organization run by volunteers. All donations are tax-deductible and go to honoring and preserving the history, experiences, successes, and lessons learned in Military Medicine. A tax receipt will be sent to you. WARDOCS documents the experiences, contributions, and innovations of all military medicine Services, ranks, and Corps who are affectionately called "Docs" as a sign of respect, trust, and confidence on and off the battlefield, demonstrating dedication to the medical care of fellow comrades in arms. Follow Us on Social Media Twitter: @wardocspodcast Facebook: WarDocs Podcast Instagram: @wardocspodcast LinkedIn: WarDocs-The Military Medicine Podcast YouTube Channel: https://www.youtube.com/@wardocspodcast

198. PANS and PANDAS (pt 2 of 2)

Pediatric Meltdown

Play Episode Listen Later Jun 12, 2024 56:48

In this second part of a 2-part series from last week's show, host Dr. Lia talks with Dr. Erica Greenberg about some of the surprising research looking at the association between autoimmune and inflammatory conditions and higher rates of OCD. Dr. Greenberg discusses the neuroscience around OCD from genetic to environmental factors, and the puzzling overlap of symptoms in disorders like Tourette's and OCD. She stresses the crucial need for interdisciplinary research to shed further light on these intricate associations. You'll get insights into why certain treatments are recommended with caution and why controversy still remains around PANDAS and the desperate need for collaboration and comprehensive research to truly understand these complex conditions. You'll also hear about the role of stress-induced inflammatory responses and how they render some individuals more susceptible to immune-related dysfunctions, shedding light on the significant impact of environmental factors like lead exposure on basal ganglia circuitry. Dr. Lia's conversation with Dr. Greenberg reveals the interconnected nature of disorders such as OCD, Tourette syndrome, and other neuropsychiatric ailments, underscoring the necessity for further research. Conversations like these illuminate the path forward, emphasizing that the key to understanding and treating these conditions lies in collaborative research efforts across various disciplines. [01:46 -12:40] Understanding PANDAS and PANS Origins and SymptomsPANDAS is specifically linked to post-infectious streptococcal etiology.PANDAS involves the sudden onset of tics and/or OCD.PANS shares a similar characteristic of sudden, rapid onset of a complex of symptoms.Importance of understanding the specific triggers and symptoms associated with both PANDAS and PANS.[12:41 - 23:32] Understanding the Clinical Outcomes of PANS/PANDAS Treatment Sudden onset of symptoms such as tics, OCD, and separation anxiety is notable in these conditions.Some children experience complete recovery back to baseline after antibiotic treatment within a week.There is ongoing research into the different potential clinical courses following a PANS/PANDAS diagnosis.Emphasis on the importance of recognizing and understanding the diverse range of clinical outcomes.[23:33 - 35:37] Genetic and Environmental Influences on OCD and Tourette SyndromeStudies show significant associations between OCD, Tourette syndrome, and increased rates of throat infections.Research indicates higher odds ratios of developing OCD and Tourette in youth with infection histories.A dose-response relationship exists between strep infections and OCD/Tourette symptom severity.Studies find higher rates of autoimmune disorders in individuals with OCD and Tourette and their family members.[35:38 - 48:00] Key Information and Challenges Surrounding PANS and PANDASNeed for more thoughtful, nuanced, safe, appropriate information for parents.There's evidence that PANS and PANDAS have a more negative impact on families compared to typical OCDOCD and Tourette syndrome develop slowly, while PANS and PANDAS show abrupt changes.Families face significant trauma, especially when providers dismiss their concerns.[48:01 - 55:17] Closing segment TakeawaysLinks to resources mentioned on the showErica Greenberg, MD PANDA AND PANS Presentation Swipe Files

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AJSM June 2024 5-in-5 Podcast

SAGE Orthopaedics

Play Episode Listen Later Jun 5, 2024 6:24

Five articles from the June 2024 issue summarized in five minutes, with the addition of a brief editorial commentary. The 5-in-5 feature is designed to give readers an overview of articles that may pique their interest and encourage more detailed reading. It may also be used by busy readers who would prefer a brief audio summary in order to select the articles they want to read in full. The featured articles for this month are, “Activity-Dependent Compensation at the Hip and Ankle at 8 Years After the Reconstruction of Isolated and Combined Posterior Cruciate Ligament Injuries,” “Performance and Return to Play After Surgery for Thoracic Outlet Syndrome in Professional Baseball Players: A Matched Cohort Analysis,” “Clinical Outcomes of Medial Meniscal Allograft Transplantation With or Without High Tibial Osteotomy: A Case-Control Study Up to 8 Years of Follow-up,” "Indirect Head of the Rectus Femoris Tendon as a Graft for Segmental Hip Labral Reconstruction: An Anatomic, Radiographical, and Biomechanical Study In Comparison With Iliotibial Labral Reconstruction," and “An Analysis of Intrapitch Variation in Joint and Segment Velocities With Throwing Arm Kinetics in High School and Professional Baseball Pitchers.” To read the articles, click here.

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Clinical Outcome of Different Microvascular Injury Patterns after STEMI - A Multicenter Cardiac MRI Study

New England Journal of Medicine Interviews

Play Episode Listen Later May 20, 2024 13:41

Commentary by Dr. Valentin Fuster

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NEJM Interview: Alicia Fernandez on the need for a focus on equity in patient experience and clinical outcomes in the health care sector.

Play Episode Listen Later May 15, 2024 10:11

Alicia Fernandez is a professor of medicine at the University of California, San Francisco. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. A. Fernandez and M.H. Chin. Keep Your Eyes on the Prize — Focusing on Health Care Equity. N Engl J Med 2024;390:1733-1736.

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Prostate Cancer Screening, Clinical Outcomes for Cancer Drugs Granted Accelerated Approval, Lupus Review, and more

JAMA Editors' Summary: On research in medicine, science, & clinical practice. For physicians, researchers, & clinicians.

Play Episode Listen Later May 7, 2024 9:28

Editor's Summary by Anne Rentoumis Cappola, MD, ScM, Associate Editor of JAMA, the Journal of the American Medical Association, for the May 7, 2024, issue.

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Magnetic Resonance Imaging Characterization and Clinical Outcomes of Dilated and Arrhythmogenic Cardiomyopathies

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Play Episode Listen Later May 6, 2024 13:40

Commentary by Dr. Valentin Fuster

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Apr 26 2024 This Week in Cardiology

This Week in Cardiology

Play Episode Listen Later Apr 26, 2024 28:20

A listener defends colored boxes in guidelines; mysteries of non-culprit coronary lesions during PCI, and of AF ablation; and surrogate markers are the topics John Mandrola, MD, covers in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Mystery of What to Do in the Cath Lab after Fixing the Culprit Lesion – The FULL REVASC Trial Complete Revascularization Not Superior to Culprit-Only PCI After MI https://www.medscape.com/viewarticle/complete-revascularization-not-superior-culprit-only-pci-2024a10007ik FULL REVASC Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2314149 FIRE Trial https://www.nejm.org/doi/10.1056/NEJMoa2300468 COMPLETE Trial https://www.nejm.org/doi/full/10.1056/NEJMoa1907775 Cohen Tweet on FULL REVASC https://x.com/djc795/status/1781361606238085532 II. AF Ablation Mysteries New Expert Consensus on Ablation Strategies for AF https://www.medscape.com/viewarticle/new-expert-consensus-ablation-strategies-af-2024a1000851 Bern Study of Remapping https://doi.org/10.1016/j.jacep.2024.02.026 Natural History of SCAF https://doi.org/10.1016/j.jacc.2019.09.050 Liverpool Study: Thermal PV Isolation in Persistent AF https://doi.org/10.1016/j.hrthm.2024.04.061 III. Surrogate Markers JAMA: Surrugate Markers and Clinical Outcomes https://jamanetwork.com/journals/jama/fullarticle/2817850 BP Surrogate Meta-analysis https://doi.org/10.1016/S0140-6736(21)00590-0 JAMA: Nonfatal MI as Surrogate for Mortality https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2785560 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

How Integrated Care Produces Superior Outcomes: HIV | Specialty Solutions; A Podcast on Improving Clinical Outcomes

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Play Episode Listen Later Apr 4, 2024 17:21

This is the second part of our four-part series outlining how the Shields Health Solutions integrated care model generates superior clinical outcomes in various complex disease states, anchored by Jennifer Donovan, PharmD, VP of Clinical Services at Shields Health Solutions. This week, we also spoke with Adaolisa Anaka, PharmD, BCACP, AAHIVP, Clinical Pharmacist at Shields Health Solutions to dive deeper into how Shields partners distinguish themselves in HIV care. Jennifer Donovan, PharmD - Vice President of Clinical Services at Shields Health Solutions and Adaolisa Anaka, PharmD, BCACP, AAHIVP - Clinical Pharmacist at Shields Health Solutions

How Integrated Care Produces Superior Outcomes: Multiple Sclerosis | Specialty Solutions; A Podcast on Improving Clinical Outcomes

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Play Episode Listen Later Mar 21, 2024 23:01

This is the final episode of our four-part series outlining how the Shields Health Solutions integrated care model generates superior clinical outcomes in various complex disease states, anchored by Jennifer Donovan, PharmD, VP of Clinical Services at Shields Health Solutions. This week, we also spoke with Alla Wilson, PharmD, Clinical Ambulatory Pharmacist at Shields Health Solutions to examine how Shields partners separate themselves in Multiple Sclerosis (MS) care. Jennifer Donovan, PharmD - Vice President of of Clinical Services at Shields Health Solutions and Alla Wilson, PharmD - Clinical Ambulatory Pharmacist at Shields Health Solutions

How Integrated Care Produces Superior Outcomes: Rheumatoid Arthritis | Specialty Solutions; A Podcast on Improving Clinical Outcomes

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Play Episode Listen Later Mar 7, 2024 24:15

How Integrated Care Produces Superior Outcomes: Rheumatoid Arthritis This is the third segment of our four-part series outlining how the Shields Health Solutions integrated care model generates superior clinical outcomes in various complex disease states, anchored by Jennifer Donovan, PharmD, VP of Clinical Services at Shields Health Solutions. This week, we also spoke with Anthony Morelli, PharmD, BCGP, CSP, Clinical Pharmacist at Shields Health Solutions to address how Shields partners set themselves apart in Rheumatoid Arthritis (RA) care. Jennifer Donovan, PharmD - Vice President of Clinical Services at Shields Health Solutions and Anthony Morelli, PharmD, BCGP, CSP - Clinical Pharmacist at Shields Health Solutions

How Integrated Care Producers Superior Outcomes: Hepatitis C | Specialty Solutions; A Podcast on Improving Clinical Outcomes