Podcasts about clinical outcomes

Real-life case studies show fasting reversed hypertension, diabetes, autoimmune diseases, and improved liver and lipid markers. #FastingResults #CaseStudies #CardiometabolicHealth #HealthTalks

In this episode of the Award-winning PRS Journal Club Podcast, 2026 Resident Ambassadors to the PRS Editorial Board – Lucas Harrison, Christopher Kalmar, and Priyanka Naidu- and special guest, Andrea L. Pusic, MD, discuss the following articles from the May 2026 issue: "Single versus Multiple Perforator Flaps in Autologous Breast Reconstruction: A Regression Analysis of Clinical Outcomes and Financial Metrics" by DeVito, Ke, Wen, et al. Read the article for FREE: https://bit.ly/MutliperfAutoBreast Dr. Andrea L. Pusic is our special guest. She serves as Chief of Plastic and Reconstructive Surgery at Brigham and Women's Hospital, Director of Patient-Reported Outcomes, and the Joseph Murray Professor of Surgery at Harvard Medical School. Dr. Pusic also holds a Master of Public Health from Johns Hopkins University. She completed her general surgery residency at Dalhousie University, followed by a plastic surgery residency at McGill University and a microsurgery fellowship at Memorial Sloan Kettering Cancer Center. Her clinical practice focuses on breast reconstruction and aesthetic breast surgery, including both autologous tissue reconstruction and implant-based techniques, with a strong emphasis on individualized, patient-centered care and quality-of-life outcomes. An internationally recognized leader in patient-reported outcomes research, Dr. Pusic has authored more than 200 publications. She developed the BREAST-Q, a widely used instrument for measuring patient satisfaction and quality of life after breast surgery. She also co-led the NCI-funded Mastectomy Reconstruction Outcomes Consortium, a multi-institutional collaboration across 11 centers studying patient perspectives on breast reconstruction. Dr. Pusic now leads the PROVE Center, where she advances the use of patient-reported outcomes to improve surgical quality, patient experience, and healthcare value. READ the articles discussed in this podcast as well as free related content: https://bit.ly/JCMay26Collection

Dr. Caroline Fenkel, DSW, LCSW, is a leader in high acuity mental healthcare and the Chief Clinical Officer and Co-Founder of Charlie Health.Dr. Fenkel oversees all aspects of Charlie Health's clinical programming, including the delivery of evidence-based care by teams of expert therapists. She's also the head of Charlie Health's industry-leading Research and Clinical Outcomes team, which regularly publishes peer-reviewed research and insights related to treating high acuity individuals.Dr. Fenkel has over 15 years of experience working with people across all levels of therapeutic care, ranging from residential to outpatient treatment. As the former Executive Director of the Center for Families, Dr. Fenkel designed, implemented, and staffed comprehensive clinical programming for high acuity intensive outpatient and partial hospitalization programs.Become a supporter of this podcast: https://www.spreaker.com/podcast/the-trauma-therapist--5739761/support.---Thank you for listening!If you want to support the show, I've got three options and every bit helps.$5.00 PayPalhttps://www.paypal.com/ncp/payment/NPKS32G8KVSN2$10.00 PayPalhttps://www.paypal.com/ncp/payment/495AMDFXQFC3L$15.00 PayPalhttps://www.paypal.com/ncp/payment/M7V5RREUKVD8JThank you to our Sponsors: Jane App - use code GUY1MO at https://jane.app (https://jane.app/book_a_demo)Novo Psych - novopsych.com/traumapodcast

Send us Fan MailIn this episode of Journal Club, Ben and Daphna dive into the results of the NIRTURE trial, recently published in JAMA Network Open. Building on the lessons of SafeBoosC 3 , the NIRTURE investigators aimed to reduce the burden of cerebral hypoxia and hyperoxia in extremely preterm infants using a standardized NIRS guided treatment protocol. While the study showed a dramatic improvement in maintaining cerebral normoxia, driven largely by a reduction in hyperoxia , the clinical outcomes before discharge remained neutral. Join us as we discuss whether regional oximetry is a must have bedside tool or just another data point in search of a clear clinical benefit.  ----Cerebral Oximetry-Guided Treatment and Cerebral Oxygenation in Extremely Preterm Infants: A Randomized Clinical Trial. Jani PR, Goyen TA, Balegar KK, Maheshwari R, Saito-Benz M, Schindler T, Moore J, Merhi M, Cruz M, Song Y, McDonagh H, Luig M, Tracy M, D'Cruz D, Perdomo A, Morakeas S, Dasireddy V, Culcer M, Shingde V, Bennington K, Michalowski J, Fucek A, Querim J, Stevens S, Santanelli J, Elhindi J, Gloss B, Halliday R, Shah D, Popat H.JAMA Netw Open. 2026 Feb 2;9(2):e2557620. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

In this special Complex Care Journal Club podcast episode, co-hosts Drs. Emily Goodwin, Kristie Malik, and Kathleen Huth interview presenters of posters and oral abstracts relevant to the care of children with medical complexity at the Pediatric Academic Societies (PAS) 2026 annual meeting, as well as at a pre-PAS event focused on home- and community-based care and training in complex care. Speakers describe their key findings, messages for care teams including patients and families, and opportunities to translate their findings into practice.‌ SPEAKERS Flor Arellano, MPH Clinical Research Coordinator, University of California, Los Angeles Jennifer Arnold, MD, MSc Medical Director, Skeletal Health, Boston Children's Hospital Ryan Brewster, MD Neonatal- Perinatal Medicine Fellow, Stanford University School of Medicine Meg Comeau, MHA Senior Project Director, Center for Innovation in Social Work & Health, Boston University School of Social Work John Greenwood, PT Executive Director for Physical Therapy, Occupational Therapy and Rehabilitation Services, Boston Children's Hospital Elaine Lin, MD Complex Care Pediatrician, Boston Children's Hospital Michelle Macy, MD, MS Professor of Pediatrics, Northwestern University Feinberg School of Medicine Scientific Director, Community, Population Health, and Outcomes, Research and Evaluation Center, Ann & Robert H. Lurie Children's Hospital of Chicago Ashley Nmoh, BA Medical Student, Duke University School of Medicine Jennifer Peralta, MD, MSHPN Assistant Clinical Professor, University of California, Los Angeles Nora Renthal, MD, PhD Assistant Professor of Pediatric Endocrinology, Boston Children's Hospital Erin Ward, MEd Patient Engagement Consultant, Complex Care Service, Boston Children's Hospital HOSTS Emily J. Goodwin, MD Clinical Associate Professor of Pediatrics, University of Missouri Kansas City School of Medicine Pediatrician, General Academic Pediatrics Beacon Program, Children's Mercy Kansas City Kristina Malik, MD Assistant Professor of Pediatrics, University of Colorado School of Medicine Medical Director, KidStreet Pediatrician, Special Care Clinic, Children's Hospital Colorado Kathleen Huth, MD, MMSc Pediatrician, Complex Care Service, Division of General Pediatrics, Boston Children's Hospital Assistant Professor of Pediatrics, Harvard Medical School DATE Initial publication date: May 11, 2026. ARTICLES REFERENCED - Brewster RC, Kats DJ, Elborki M, Chilukuri N, Ray M, Shaar N, Hron J, Khan A. Clinical Outcomes of Postedited Artificial Intelligence Translation for Discharge Instructions. Hosp Pediatr. 2026 Apr 10:e2025008986. doi: 10.1542/hpeds.2025-008986. Epub ahead of print. PMID: 41956490. - FamilyCIRCLE. University of Wisconsin–Madison, Department of Pediatrics. Accessed May 4, 2026. https://familycircle.pediatrics.wisc.edu/ - Pediatric Academic Societies. Online program guide. Accessed May 4, 2026. https://2026.pas-meeting.org/ - Pediatric Academic Societies. Who we are. Accessed May 4, 2026. https://www.pas-meeting.org/about/ - Pediatric Academic Societies. Academic Pediatric Association (APA) awards. Accessed May 4, 2026. https://www.pas-meeting.org/2026-awards-apa/‌ TRANSCRIPT https://cdn.bfldr.com/D6LGWP8S/as/k7qqm93qqpqgb5k3jw4f3w2t/PAS_2026_conference_transcript_5-8-26‌ Clinicians across healthcare professions, advocates, researchers, and patients/families are all encouraged to engage and provide feedback! You can recommend an article for discussion using this form: https://forms.gle/Bdxb86Sw5qq1uFhW6. CITATION Goodwin EJ, Malik K, Arellano F, Arnold J, Brewster R, Comeau M, Greenwood J, Lin E, Macy M, Nmoh A, Peralta J, Renthal N, Ward E, Huth K. Practice-Changing Research in Complex Care at the Pediatric Academic Societies 2026 Annual Meeting. 05/2026. OPENPediatrics. Online Podcast. https://soundcloud.com/openpediatrics/practice-changing-research-in-complex-care-pediatric-academic-societies-2026.

Dr. Thomas Johnson returns to the podcast. Dr. Emily Schehlein interviews him on his study to assess the clinical outcomes of Hydrus Microstent implantation with cataract extraction for the treatment of open-angle glaucoma. From the Ophthalmology Glaucoma article, Clinical Outcomes of Hydrus Microstent Implantation for Open-Angle Glaucoma: Results from a Large Academic Center. Clinical Outcomes of Hydrus Microstent Implantation for Open-Angle Glaucoma. Hamilton, Natalie R. et al. Ophthalmology Glaucoma, Volume 9, Issue 1, 48 - 61

Commentary by Dr. Leandra Serio.

Commentary by Dr. Satoshi Shizuta.

This episode recorded live at the Becker's 16th Annual Meeting features Jennifer Jones, Director of Clinical Solutions, Noom. Here, she explores how GLP-1s should be viewed as part of chronic disease management rather than a pharmacy-only cost issue, and how payer strategies that combine medication access with behavior change programs can improve long-term clinical outcomes and deliver more sustainable ROI.This episode is sponsored by Noom Health.

This episode debunks the myth that glucagon is a stress hormone and explains its vital role in human metabolism, especially in ketogenic diets. It clarifies misconceptions, discusses scientific studies, and highlights the positive health outcomes of low-carb and carnivore diets.Chapters00:00 Understanding Glucagon: The Misconception of a Stress Hormone01:27 Physiological Role of Glucagon in Metabolism04:43 The Context of Hormonal Responses in Diet07:37 Clinical Outcomes of Ketogenic Diets10:33 Debunking Myths: Glucagon and Stress13:23 Trusting Your Body: The Science of GlucagonReferences at https://open.substack.com/pub/theukcarnivore/p/the-glucagon-stress-hormone-nonsense?r=14wb5g&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true

In this podcast, Praveen Goday discusses his paper 'Weight measurements and disease-specific growth charts to predict clinical outcomes in children with cerebral palsy'. The paper is available here: https://doi.org/10.1111/dmcn.70204 Follow DMCN on Podbean for more: https://dmcn.podbean.com/ ___ Watch DMCN Podcasts on YouTube: https://bit.ly/2ONCYiC __ DMCN Journal: Developmental Medicine & Child Neurology (DMCN) has defined the field of paediatric neurology and childhood-onset neurodisability for over 60 years. DMCN disseminates the latest clinical research results globally to enhance the care and improve the lives of disabled children and their families. DMCN Journal - https://onlinelibrary.wiley.com/journal/14698749 ___ Find us on Twitter! @mackeithpress - https://twitter.com/mackeithpress

In this podcast, Judy-April Murayi & Praveen Goday discuss their paper 'Weight measurements and disease-specific growth charts to predict clinical outcomes in children with cerebral palsy'. The paper is available here: https://doi.org/10.1111/dmcn.70204 Follow DMCN on Podbean for more: https://dmcn.podbean.com/ ___ Watch DMCN Podcasts on YouTube: https://bit.ly/2ONCYiC __ DMCN Journal: Developmental Medicine & Child Neurology (DMCN) has defined the field of paediatric neurology and childhood-onset neurodisability for over 60 years. DMCN disseminates the latest clinical research results globally to enhance the care and improve the lives of disabled children and their families. DMCN Journal - https://onlinelibrary.wiley.com/journal/14698749 ___ Find us on Twitter! @mackeithpress - https://twitter.com/mackeithpress

Send us Fan MailWhat if food worked better than medication for managing diabetes?In this clip from our episode “Food As Medicine: From Trend to Treatment”, CareTalk host John Driscoll and guest Spencer Pratt, Chief Growth Officer at NourishedRx, share the clinical data behind their food as medicine approach to diabetes care.

Join an expert-led discussion exploring the safety and clinical outcomes of Class 1c antiarrhythmic therapy following percutaneous coronary intervention (PCI) in patients with new-onset atrial fibrillation, based on insights from a nationwide cohort study. Deep Chandh Raja, MBBS, MD, PhD (Australian National University and Kauvery Hospital) hosts a dynamic conversation with Sandeep Gautam, MD, MPH, FHRS (University of Missouri Health) and Deepak Padmanabhan, MD, FHRS (Narayana Institute of Cardiac Sciences, Bengaluru). Together, they examine real-world data on the use of Class 1c agents in a traditionally high-risk population, addressing long-standing concerns about proarrhythmia and ischemic heart disease. The discussion will highlight patient selection, evolving clinical practice patterns, and implications for guideline-directed management, offering clinicians practical insights into optimizing rhythm control strategies in complex post-PCI patients. Learning Objectives Evaluate the safety profile and clinical outcomes associated with Class 1c antiarrhythmic therapy in patients with new-onset atrial fibrillation following PCI.  Identify appropriate patient selection criteria and clinical considerations when prescribing Class 1c agents in the context of ischemic heart disease. Apply evidence from nationwide cohort data to inform decision-making and optimize rhythm management strategies in post-PCI atrial fibrillation patients. Link to the Article for Discussion Article AuthorsTing-Chun Huang MD, Po-Hsueh Su MD, Hui-Wen Lin MS, Po-Tseng Lee MD, Yu Liao MD, Chao-Yu Chen MD, Li-Hao Yap MD, Sheng-Hsiang Lin PhD, Yi-Heng Li MD, PhD Podcast ContributorsDeep Chandh Raja, MBBS, MD, PhD Sandeep Gautam, MD, MPH, FHRS Deepak Padmanabhan, MD, FHRS   Host and Contributor Disclosure(s): D.C. RajaNothing to disclose. S. Gautam Honoraria/Teaching/Speaking/Consulting: Biosense Webster Fellowship Support: Medtronic Inc., Abbott D. Padmanabhan Nothing to disclose.

From Korea to the Marshall Islands, plant-based diets consistently outperform conventional diabetes diets. Learn how these interventions changed lives and reversed disease. #PlantBasedCures #WholeFoods #GlobalHealth

In his weekly clinical update, Dr. Griffin and Vincent Racaniello chat about death of water fowl on Long Island, 'renaming' of the FDA adverse event monitoring system, lawsuits against RFK Jr and HHS for illegal changes in routine immunization practices, before Dr. Griffin deep dives into economic costs of not vaccinating against measles, the measles outbreak in South Carolina, Utah and ICE detention centers, recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, expansion of the RSV vaccine licensure to include high risk yound adults, association between lung cancer and respiratory illnesses, how to access and pay for Paxlovid, effectiveness of vaccination or supplemental vitamin D to reduce the risk of long COVID, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Local waterfowl die-off likely caused by bird flu (The Suffolk Times) East End officials respond as dead birds pile up on Long Island shorelines (news 12: Long Island) FDA Adverse Event Monitoring System(AEMS)(FDA) FDA Launches NewAdverse Event Look-Up Tool(FDA) FDA announces AEMS, new adverse-event database to replace VAERS (CIDRAP) US cuts broad recommendation for four childhood vaccines including flu (Reuters) US CDC deploys staff to curb South Carolina's measles outbreak (Reuters) US judge upends Kennedy's overhaul of childhood vaccine policies (Reuters) American Academy of Pediatrics, et al v. Robert F Kennedy, Jr, et al (Civil Action No 25-11916-BEM) White House Puts RFK Jr.'s HHS on Tighter Leash After MAHA Setbacks(Wall Street Journal) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard(South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services) Utah Measles Dashboard (Utah Department of Health and Human Services) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots(CIDRAP) Weekly surveillance report: clift notes (CDC FluView) OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Respiratory Diseases (Yale School of Public Health) FDA expands approval for RSV vaccine to include younger adults at high risk (FDA) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Respiratory viral infections prime accelerated lung cancer growth (Cell) 2024–2025 COVID-19 mRNA Vaccine Effectiveness Against Severe Disease (JID) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulationguidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Effectiveness of COVID-19 Vaccination and Prior Infections to Reduce Long COVID Risk During the Pre-Omicron and Omicron Periods (CID) A Randomized Trial of Vitamin D Supplementation and COVID-19 Clinical Outcomes and Long COVID: The Vitamin D for COVID-19 Trial (The Journal of Nutrition) Long COVID Treatment Guide (rthm) Reaching out to US house representative Letters read on TWiV 1306 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

Aaron M. Pulsipher, MD, joins CHEST® Journal Podcast Moderator Matt Siuba, DO, MS, to discuss his research into the dose-response relationship between adjunctive corticosteroids and outcomes in adult patients with non-HIV Pneumocystis jirovecii pneumonia.  DOI: 10.1016/j.chest.2025.10.036 Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers' opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine. 

Welcome to the latest episode of L.I.F.T.S,  your bite-sized dose of the Latest Industry Fitness Trends and Stories. In this special live episode from the Connected Health & Fitness Summit 2026 in Los Angeles, Matthew Januszek and Mohammed Iqbal sit down with four leaders shaping the future of performance, longevity, franchising, and workforce training. Guests include: Douglas Gremmen (HYROX): On building one of the fastest growing competitive fitness brands in the world and why purpose-driven training is the ultimate disruptor. Dean Kelly (Extension Health): On physician-led longevity, advanced diagnostics, and the shift from conversation to clinical outcomes. Julie Cartwright (PVOLVE): On scaling an omni-channel fitness brand and the emotional responsibility of franchising. This episode explores the balance between AI and human intelligence, the rise of team-based competition, the evolution of longevity medicine, and how modern training systems are transforming frontline industries. Key Topics Include: How HYROX built a global competitive ecosystem without competing with gyms. Why doubles competition is redefining community in fitness. The difference between influencer-driven biohacking and physician-led longevity care. The realities of scaling a franchise brand in today's market. How AI-powered training systems are improving workforce performance. The importance of human connection in an AI-native world.

This episode critically examines a recent Nature Medicine paper on the timing of immune therapy infusion in lung cancer, exploring the scientific plausibility, methodological concerns, and implications for future research. Tom, Brian and David McDermott debate the validity of the findings, the review process, and the need for rigorous prospective trials.

In this episode of the Unreal Results podcast, I share a candid look at expectations in clinical practice, especially after learning a new framework like the LTAP®. I break down why early wins can create unrealistic internal pressure, how I think about my 1-3 session benchmark, and why managing patient expectations is often the missing piece in overcoming imposter syndrome. I also walk through a real case example of a Navy SEAL BUD/S candidate to show how I decide when to adjust the plan, refer out, or stay the course.In this episode, you'll hear:What “guaranteeing results” really means and what it doesn'tWhy mismatching assessment precision with treatment precision can worsen outcomesHow expectations (yours vs. your patient's) shape confidence and resultsThe six questions that dramatically improve clarity, buy-in, and clinical directionIf you're a clinician who wants better results without burning yourself out or second-guessing every session, this episode will sharpen your reasoning and steady your confidence.Resources & Links Mentioned In This Episode:Ep. 119: Guaranteeing Results... Until You Can'tEp. 125: You're Already Treating The Viscera... You Just Don't Know ItEp. 126: How Many Sessions Do Clients Really Need?Ep. 131: Raising The Bar On Patient OutcomesLearn the LTAP® In-Person in one of my upcoming coursesConsidering the viscera as a source of musculoskeletal pain and dysfunction is a great way to ensure a more true whole body approach to care, however it can be a bit overwhelming on where to start, which is exactly why I created the Visceral Referral Cheat Sheet. This FREE download will help you to learn the most common visceral referral patterns affecting the musculoskeletal system. Download it at www.unrealresultspod.com=================================================Watch the podcast on YouTube and subscribe!Join the MovementREV email list to stay up to date on the Unreal Results Podcast and MovementREV education. Be social and follow me:Instagram | Facebook | Twitter | YouTube

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Associations of Electromechanical Activation Time With Cardiac Structure and Function and Clinical Outcomes.

Picture this: a patient with early-stage breast cancer is sitting in front of you in the clinic. You are about to offer your expert management plan. The age-old question arises—should you really perform a sentinel lymph node biopsy, or could omission actually help this patient more? Today, we're tackling one of the hottest debates in modern breast cancer care.Should we rethink sentinel lymph node biopsy for select patients, and can skipping it actually improve quality of life without sacrificing cancer control? The stakes couldn't be higher—balancing accurate cancer staging and minimizing harm is the name of the game. Together, we're breaking down the latest evidence from the SOUND and INSEMA trials. What do these landmark studies mean for your patients, your practice, and the future of axillary management? Ready for a journal review that might just change your next consult? Hosts:- Rashmi Kumar, MD, PhDResident, University of Michigan General Surgery Residency ProgramTwitter/X: @RashmiJKumar- Melissa Pilewskie, MDAttending Breast Surgical Oncologist, Co-Director of the Weiser Family Center for Breast Cancer, Michigan Medicine Twitter/X: @MPilewskie- Stephanie Downs-Canner, MDAttending Breast Surgical Oncologist & Physician-Scientist, Memorial Sloan Kettering Cancer Center, Program Director of the Breast Surgical Oncology Fellowship Training Program Twitter/X: @SDownsCannerLearning Objectives:- Understand when and for whom it is safe and beneficial to omit sentinel lymph node biopsy (SLNB) in early-stage breast cancer patients.- Identify the risks associated with foregoing SLNB, including loss of nodal staging, and analyze how this impacts treatment selection and prognosis.- Review key findings from the SOUND and INSEMA trials and their influence on axillary management.- Discuss implications for adjuvant therapy, genomic profiling, and multidisciplinary clinical practice.- Recognize which patient populations should still receive SLNB, and the importance of individualized, multidisciplinary decision-making.References:- Gentilini OD, Botteri E, Sangalli C, et al. Sentinel Lymph Node Biopsy vs No Axillary Surgery in Patients With Small Breast Cancer and Negative Results on Ultrasonography of Axillary Lymph Nodes: The SOUND Randomized Clinical Trial. JAMA Oncol. 2023;9(11):1557–1564. doi:10.1001/jamaoncol.2023.3759 https://pubmed.ncbi.nlm.nih.gov/37733364/- Reimer T, Stachs A, Veselinovic K, et al. Axillary surgery in breast cancer – primary results of the INSEMA trial. N Eng J Med. 2024. doi:10.1056/NEJMoa2412063.https://pubmed.ncbi.nlm.nih.gov/39665649/- Sparano JA, Gray RJ, Makower DF, Albain KS, Saphner TJ, Badve SS, Wagner LI, Kaklamani VG, Keane MM, Gomez HL, Reddy PS, Goggins TF, Mayer IA, Toppmeyer DL, Brufsky AM, Goetz MP, Berenberg JL, Mahalcioiu C, Desbiens C, Hayes DF, Dees EC, Geyer CE Jr, Olson JA Jr, Wood WC, Lively T, Paik S, Ellis MJ, Abrams J, Sledge GW Jr. Clinical Outcomes in Early Breast Cancer With a High 21-Gene Recurrence Score of 26 to 100 Assigned to Adjuvant Chemotherapy Plus Endocrine Therapy: A Secondary Analysis of the TAILORx Randomized Clinical Trial. JAMA Oncol. 2020 Mar 1;6(3):367-374. doi: 10.1001/jamaoncol.2019.4794. PMID: 31566680; PMCID: PMC6777230. https://pubmed.ncbi.nlm.nih.gov/31566680/- Slamon DJ, Fasching PA, Hurvitz S, Chia S, Crown J, Martín M, Barrios CH, Bardia A, Im SA, Yardley DA, Untch M, Huang CS, Stroyakovskiy D, Xu B, Moroose RL, Loi S, Visco F, Bee-Munteanu V, Afenjar K, Fresco R, Taran T, Chakravartty A, Zarate JP, Lteif A, Hortobagyi GN. Rationale and trial design of NATALEE: a Phase III trial of adjuvant ribociclib + endocrine therapy versus endocrine therapy alone in patients with HR+/HER2- early breast cancer. Ther Adv Med Oncol. 2023 May 29;15:17588359231178125. doi: 10.1177/17588359231178125. Erratum in: Ther Adv Med Oncol. 2023 Sep 29;15:17588359231201818. doi: 10.1177/17588359231201818. PMID: 37275963; PMCID: PMC10233570. https://pubmed.ncbi.nlm.nih.gov/37275963/Sponsor Disclosure: Visit goremedical.com/btkpod to learn more about GORE® SYNECOR Biomaterial, including supporting references and disclaimers for the presented content. Refer to Instructions for Use at eifu.goremedical.com for a complete description of all applicable indications, warnings, precautions and contraindications for the markets where this product is available. Rx only Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.  If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listenBehind the Knife Premium:General Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-reviewTrauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlasDominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkshipDominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotationVascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-audio-reviewColorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-audio-reviewSurgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-audio-reviewCardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-audio-reviewDownload our App:Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US

Peripheral artery disease has been called the ‘silent circulatory crisis'—affecting millions, limiting mobility, and quietly raising the risk of heart attack, stroke, and limb loss. For decades, treatment focused on walking programs, aspirin, and sometimes a stent or bypass. But today, the landscape is changing. From PCSK9 inhibitors that drive cholesterol to record lows, to GLP-1 agonists like semaglutide improving walking distance, to novel antithrombotic strategies that balance bleeding and clotting—PAD care is entering a new era. In this episode, we'll explore the breakthroughs, the evidence behind them, and what they mean for patients who just want to keep moving forward." Hosted by the University of Michigan Department of Vascular Surgery: - Robert Beaulieu, Program Director - Frank Davis, Assistant Professor of Surgery - Luciano Delbono, PGY-5 House Officer - Andrew Huang, PGY-4 House Officer - Carolyn Judge, PGY-2 House Officer Learning objectives:  1.  Describe the current evidence-based recommendations for multifactorial medical management of peripheral artery disease (PAD), including lipid, glycemic, and antithrombotic strategies per 2024 SVS/AHA guidelines.  2. Interpret the clinical implications of the FOURIER trial regarding the role of PCSK9 inhibition in reducing cardiovascular events in patients with atherosclerotic disease, including PAD.  3.  Evaluate the emerging role of GLP-1 receptor agonists, such as semaglutide, in improving walking performance and quality of life among patients with diabetic PAD based on findings from the STRIDE trial. Sponsor URL: https://www.goremedical.com/ References:  H. L. Gornik et al., “2024 ACC/AHA/AACVPR/APMA/ABC/SCAI/SVM/SVN/SVS/SIR/VESS Guideline for the Management of Lower Extremity Peripheral Artery Disease,” JACC, vol. 83, no. 24, pp. 2497–2604, June 2024, doi: 10.1016/j.jacc.2024.02.013. L. Mazzolai et al., “2024 ESC Guidelines for the management of peripheral arterial and aortic diseases: Developed by the task force on the management of peripheral arterial and aortic diseases of the European Society of Cardiology (ESC) Endorsed by the European Association for Cardio-Thoracic Surgery (EACTS), the European Reference Network on Rare Multisystemic Vascular Diseases (VASCERN), and the European Society of Vascular Medicine (ESVM),” Eur Heart J, vol. 45, no. 36, pp. 3538–3700, Sept. 2024, doi: 10.1093/eurheartj/ehae179. https://pubmed.ncbi.nlm.nih.gov/40169145/ M. S. Sabatine et al., “Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease,” N Engl J Med, vol. 376, no. 18, pp. 1713–1722, May 2017, doi: 10.1056/NEJMoa1615664. https://pubmed.ncbi.nlm.nih.gov/28304224/ M. P. Bonaca et al., “Semaglutide and walking capacity in people with symptomatic peripheral artery disease and type 2 diabetes (STRIDE): a phase 3b, double-blind, randomised, placebo-controlled trial,” Lancet, vol. 405, no. 10489, pp. 1580–1593, May 2025, doi: 10.1016/S0140-6736(25)00509-4. https://pubmed.ncbi.nlm.nih.gov/40169145/ N. E. Hubbard, D. Lim, and K. L. Erickson, “Beef tallow increases the potency of conjugated linoleic acid in the reduction of mouse mammary tumor metastasis,” J Nutr, vol. 136, no. 1, pp. 88–93, Jan. 2006, doi: 10.1093/jn/136.1.88. https://pubmed.ncbi.nlm.nih.gov/16365064/ Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.   If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listen Behind the Knife Premium: General Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-review Trauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlas Dominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkship Dominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotation Vascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-audio-review Colorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-audio-review Surgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-audio-review Cardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-audio-review Download our App: Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049 Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US

3-Year Clinical Outcomes of the REC-CAGEFREE I Trial

Today, I am delighted to be joined by a friend and colleague, Mike Mutzel.  Mike has a master's in Clinical Nutrition from the University of Bridgeport. He is a graduate of the IFM, applies functional medicine in clinical practice, and is a consultant lecturer who teaches leading-edge science in a concise format for progressive clinicians to prevent chronic diseases.  In our discussion, Mike and I unpack the benefits of creatine monohydrate, highlighting the importance of ensuring the products we use are free of impurities. We explain how creatine monohydrate gets created, answer many listener questions, and describe current research specific to creatine monohydrate, discussing ways to support bone health, navigate dosing, and how to troubleshoot.  This conversation with Mike Mutzel is truly invaluable, and I look forward to having him back on the podcast to dive a little deeper into the science.  IN THIS EPISODE, YOU WILL LEARN: How creatine supports energy production across muscles, the brain, and other organ systems Why vegetarians and vegans should take creatine What to consider when choosing high-quality creatine supplements Dosing strategies based on diet, exercise, sleep, and individual needs How taking creatine with electrolytes while exercising can improve absorption Benefits of supplementing with amino acids alongside creatine for illness, recovery, or when protein intake is low Adjusting your creatine dosage for sleep, travel, or exercise demands How creatine supports bone and muscle health  The value of creatine for the eyes and ears Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Connect with Mike Mutzel On his website YouTube Instagram High Intensity Health Podcast Creatine Research: Creatine in Women's Health: Bridging the Gap From Menstruation Through Pregnancy to Menopause Effects of Creatine and Resistance Training on Bone Health in Postmenopausal Women Creatine Supplementation (3 g/d) and Bone Health in Older Women: A 2-Year, Randomized, Placebo-Controlled Trial Creatine Supplementation in Depression: A Review of Mechanisms, Efficacy, Clinical Outcomes, and Future Directions The Effects of 8-Week Creatine Hydrochloride and Creatine Ethyl Ester Supplementation on Cognition, Clinical Outcomes, and Brain Creatine Levels in Perimenopausal and Menopausal Women (CONCRET-MENOPA): A Randomized Controlled Trial

Episode Overview In this special episode of the Behavioral Observations Podcast, I had the honor of celebrating the 25th installment of the Inside JABA Series. This one was particularly meaningful because it also marks the final appearance of Dr. John Borrero in his role as Editor-in-Chief of The Journal of Applied Behavior Analysis. I invited John to reflect on his three-year tenure—what he learned from reading an enormous volume of manuscripts, how his thinking evolved, and why adapting our language is essential if we want behavior analysis to reach broader audiences. From there, we transitioned into an informative conversation with Dr. Nate Call from Emory University. Nate's recent work focuses on how we can better disseminate applied behavior analysis, not just distribute it. His paper, Scholarship as an Operating Class: Strategies and tactics for increasing dissemination of applied behavior analysis, has already shifted how I think about how our field packages and shares research. In this episode, Nate walked us through actionable strategies for increasing the reach and impact of our work. Key Topics Covered in This Episode 1. John Borrero's Reflections from the Editor's Chair John looked back on his three years as Editor-in-Chief, and I asked him what surprised him most. He talked about: How important clear, accessible language is for dissemination Why behavior analysts must evolve how we communicate without losing our scientific roots Efforts to make JABA papers more accessible through translated articles What it's like to manage a massive editorial workflow and team 2. The Real Difference Between Dissemination and Distribution Nate clarified something that—and I'll admit—I hadn't always thought deeply about: there's a big difference between making your work available and ensuring your work is actually used. Nate described it like: Distribution = scattering seeds Dissemination = preparing the soil so they actually grow He also explained why early-career researchers often focus on distribution out of necessity, and how we can transition to more deliberate dissemination strategies over time. 3. Scholarship as an Operant Class Nate walked me through the framework behind his recent paper. He described scholarly behavior as something shaped by contingencies—just like anything else. We talked about: How individual and systemic consequences shape publishing choices Why some of the most high-impact papers come from individuals rather than large labs Concrete strategies we can use to increase the visibility and influence of our work 4. Boundary Encounters and Second-Generation Innovations I asked Nate about how ideas move between disciplines, and he introduced the concept of boundary encounters. We discussed: Incoming vs. outgoing boundary encounters How second-generation innovations help behavior analysis reach audiences outside our traditional spaces Why these interactions are essential if we want ABA to have a broader societal impact 5. Expanding Our Methodological Toolkit We took a deep dive into methodology and talked about the strengths of single-subject designs—as well as their limitations. Nate made a compelling case for: When behavior analysts should consider Randomized Control Trials, implementation science, or mixed methods Why diversifying methodologies helps us answer questions that matter to educators, policymakers, and grant reviewers What we lose when we rely exclusively on traditional single-subject approaches 6. Participatory Action Research and Social Validity I asked Nate to explain participatory action research, and he shared a powerful example involving first responders and families in crisis situations. He emphasized: The importance of involving stakeholders early How PAR elevates social validity and context Why many federal funders now expect qualitative or participatory components How behavior analysts can begin building these skills, even if it feels unfamiliar 7. Measuring Our Impact More Effectively We also explored how to know whether dissemination is working. Nate and I discussed: Bibliographic network analysis Alt-metric measures The importance of citing intentionally to strengthen high-quality scholarship within the field 8. Nate's Advice for New BCBAs To close the episode, I asked Nate what he'd tell new behavior analysts entering the field. He encouraged them to: Read widely—far beyond behavior-analytic journals Become conversant in different research methods Build collaborations with experts in qualitative, mixed, and implementation-science approaches Think functionally about their own scholarly and professional behavior 9. Resources Mentioned in this Podcast Foxx (1996). Translating the Covenant: The behavior analyst as ambassador and translator Chawla (2020). Science is getting harder to read Critchfield, et al. (2013). A half century of scalloping in the work habits of the United States Congress Klein and Thompson (2025). Abundance The Prisoner's Dilemma Call et al. (2015). Clinical Outcomes of Behavioral Treatments for Pica in Children with Developmental Disabilities Critchfield (2002). Evaluating the function of Applied Behavior Analysis: A bibliometric analysis Inside JABA 18: How to Disseminate Behavior Analytic Technologies (CEU available!) Implementation Science and Participatory Action Research If you're passionate about increasing the influence of behavior analysis—whether through research, writing, teaching, or practice—this episode offers clear, functional guidance for how to do it.

Creatine isn't just for gym bros and bodybuilders, it's one of the most researched, safest, and most effective supplements for supporting strength, energy, and brain health.In this episode, I break down a brand-new study that found women in perimenopause and menopause who took a small daily dose of creatine saw faster reaction times, better cholesterol levels, and even a 16% increase in brain creatine.We'll cover:

Katarina Zeder, MD, PhD, joins CHEST® Journal Podcast Moderator Matt Siuba, DO, MS, to discuss her research into the ways in which longitudinal pulmonary arterial pressure trajectories inform clinical outcome in patients undergoing kidney transplantation.  DOI: 10.1016/j.chest.2025.05.024 Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers' opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine. 

Few nutrients get as much hype as vitamin D. It's been promoted for everything from stronger bones and better mood to reduced risk of chronic disease and cancer prevention. And during the COVID-19 pandemic, a wave of self-proclaimed “vitamin D truthers” took things further—claiming massive doses could prevent or even cure the virus. But what does the science actually say about how much Vitamin D you should be taking? And are there truly health benefits of mega-dosing Vitamin D? Join us, two Registered Dietitians, as we dig into the ‘sunshine vitamin' and shed light on the facts (and fiction) surrounding this much-debated nutrient.Want to support the show and get bonus episodes? Join our Patreon! https://www.patreon.com/nutritionformortalsWe've got MERCH! Check it out HEREDon't want to miss any episodes in the future? Make sure to subscribe wherever you listen to podcasts!Things we talked about and additional reading: Sunlight and Vitamin D: A global perspective for health The Vit D-Folate Hypothesis for Skin Pigmentation (and other hypotheses)Unexpected actions of vit D in innate and adaptive immunity Vit D Supplementation and depression meta-analysis of RCTs Vit D status and COVID-19 severity (observational data #1)Vit D status and COVID-19 severity (observational data #2)Vit D from cod liver oil and and COVID-19 incidence Vit D Supplementation with single high dose and hospital LOS in COVID-19 RCT Vit D Supplementation and COVID-19 review/meta-analysis Vit D Supplementation in COVID-19 for deficiency COVID-19 and Vit D Misinformation on Youtube Analysis Vit D Supplementation on Clinical Outcomes in Older Adults Vit D Supplementation and Prevention of Cancer and CVDVit D and Cancer Risk / Mortality Research Challenges The effect of sunscreen on vit D review Sunlight: Time for a Rethink? FTC charges Eric Nepute for Violations For feedback or to suggest a show topic email us at nutritionformortals@gmail.comFeel free to contact our real, live nutrition counseling practice**This podcast is for information purposes only, is not a substitute for individual medical or mental health advice, and does not constitute a patient-provider relationship**

Commentary by Dr. Nicolas Palaskas & Dr. Keila Ostos-Mendoza.

This week we review an episode from 3 years back and delve into the world of adult congenital heart disease when we review a recent work from the ACHD team at UCSF that assesses the impact of BMI on clinical outcomes in the single ventricle adult Fontan patient. What is the cause of elevation in BMI in some Fontan patients? Is obesity the only explanation? Is BMI a modifiable risk factor for our Fontan patients and should exercise be 'prescribed' for these patients? If so prescribed, what type of exercise is best for the Fontan patient? This week's work's senior author, Dr. Anushree Agarwal, Assistant Professor of Medicine at UCSF, shares her insights into this important topic. DOI: 10.1161/JAHA.122.026732Also mentioned in today's episode is episode #222 with Dr. Dan Halpern of NYU medical center (https://www.stitcher.com/show/pediheartpediatric-cardiology-today/episode/pediheart-podcast-222-impact-of-cardiac-rehab-on-exercise-tolerance-in-the-achd-patient-206781483)

Send us a textIn this episode, we cover the anatomy and functions of the menisci, the mechanisms behind various types of meniscal tears, and clinical assessment techniques. We also discuss when to opt for conservative care versus surgical treatment, and reviews special tests and imaging standards like MRIs. Tune in to enhance your understanding of knee meniscal injuries and improve your clinical practice.00:00 Introduction to Bets Snacks Podcast00:23 Overview of Knee Meniscal Tears00:54 Anatomy and Function of the Menisci03:03 Types of Meniscal Tears05:58 Clinical Assessment Techniques08:15 Imaging and Diagnosis09:04 Conservative vs. Surgical Treatment12:03 Conclusion and Additional ResourcesBeamer BS, Walley KC, Okajima S, et al. (2017). Meniscal Repair vs Partial Meniscectomy: A Comparative Analysis of Clinical Outcomes. Arthroscopy, 33(9), 1635–1643.Englund M, Guermazi A, Gale D, et al. (2008). Incidental Meniscal Findings on Knee MRI in Middle-Aged and Elderly Persons. New England Journal of Medicine, 359(11), 1108–1115.Logerstedt DS, Scalzitti D, Risberg MA, et al. (2010). Knee Pain and Mobility Impairments: Meniscal and Articular Cartilage Lesions. Journal of Orthopaedic & Sports Physical Therapy (JOSPT) Clinical Practice Guidelines, 40(6), A1–A35.LaPrade RF, Geeslin AG, Everett CR, et al. (2015). Diagnosis and Treatment of Meniscal Injuries: A Review. Sports Health, 7(2), 147–154.Stensrud S, Risberg MA, Roos EM. (2012). Effect of Exercise Therapy on Meniscal Tear Outcomes in Middle-Aged Adults: A Randomized Controlled Trial. British Medical Journal (BMJ), 344:e533.Go to PT Final Exam using this link to access great studying options to conquer the NPTE!Support the showStay Connected! Make sure to hit follow now so you don't miss an episode! Got questions? Email me at ptsnackspodcast@gmail.com or leave feedback HERE. You can also join the email list HERE Need CEUs Fast?Time and resources short? Medbridge has you covered: Get over $100 off a subscription with code PTSNACKSPODCAST: Medbridge Students: Save $75 off a student subscription with code PTSNACKSPODCASTSTUDENT—a full year of unlimited access for less! Prepping for the NPTE? Get all the study tools you need to master it at PT Final Exam. Use code PTSnacks at checkout to get a discount! Want to Support the Show?Help me keep creating free content by: Sharing the podcast with someone who'd benefit. Contributing directly via the link...

In recent years, anterior cruciate ligament (ACL) injuries in children and adolescents (age ≤18 years) have been increasing, and the quadriceps tendon (QT) autograft has been gaining popularity for ACL reconstruction. However, there is no consensus regarding the graft choice for ACL reconstruction in these young patients. There has been a paucity of literature comparing the functional outcomes of hamstring tendon (HT) and QT autografts for ACL reconstruction in patients aged ≤18 years.   In conclusion, a QT autograft for ACL reconstruction led to similar clinical outcomes, revision rates, and sports participation compared with an HT autograft in pediatric and adolescent patients.   Click here to read the article.

What if menopause wasn't something to “get through,” but a time to reconnect with your body in an entirely new way? In this solo episode for Menopause Month, I'm diving deep into what's really happening beneath the surface during perimenopause and menopause - and how you can support your body through every change with nourishment and care.We'll explore how nutrition can protect your bone and heart health, help you maintain muscle mass, and even support brain health during this transition. We'll also unpack the link between hormones and cognitive function, including what we know about Alzheimer's risk and how lifestyle can make a difference.What we cover in this episode:Perimenopause + menopause — what's really happening underneathNourishing your body through this phase: bone, heart, and muscle healthThe brain connection: Alzheimer's risk + supporting cognitive resilienceWhat to focus on next to feel your best in midlife and beyondWhether you're just starting to notice changes or already in the thick of it, this episode is here to help you feel informed, empowered, and deeply connected to your body's evolution. Enjoyed the podcast? Please leave us a rating and review, we'd love to hear it! Links:1-on-1 nutrition programs for menopause: ThegoodlifedietitianServices — Trista Chan RD, MHScMenopause IG series   ReferencesAtaei Kachouei A, Singar S, Wood A, Flatt JD, Rosenkranz SK, Rosenkranz RR, Akhavan NS. Cardiovascular Risk Factors, Alzheimer's Disease, and the MIND Diet: A Narrative Review from Molecular Mechanisms to Clinical Outcomes. Nutrients. 2025 Jul 16;17(14):2328. doi: 10.3390/nu17142328. PMID: 40732953; PMCID: PMC12299063. Glenn AJ, Guasch-Ferré M, Malik VS, Kendall CWC, Manson JE, Rimm EB, Willett WC, Sun Q, Jenkins DJA, Hu FB, Sievenpiper JL. Portfolio Diet Score and Risk of Cardiovascular Disease: Findings From 3 Prospective Cohort Studies. Circulation. 2023 Nov 28;148(22):1750-1763. doi: 10.1161/CIRCULATIONAHA.123.065551. Epub 2023 Oct 25. PMID: 37877288; PMCID: PMC10841173. Inaraja V, Thuissard I, Andreu-Vazquez C, Jodar E. Lipid profile changes during the menopausal transition. Menopause. 2020 Jul;27(7):780-787. doi: 10.1097/GME.0000000000001532. PMID: 32187130. Kodete, C. S., Thuraka, B., Pasupuleti, V., & Malisetty, S. (2024). Hormonal Influences on Skeletal Muscle Function in Women across Life Stages: A Systematic Review. Muscles, 3(3), 271-286. Ryczkowska K, Adach W, Janikowski K, Banach M, Bielecka-Dabrowa A. Menopause and women's cardiovascular health: is it really an obvious relationship? Arch Med Sci. 2022 Dec 10;19(2):458-466. doi: 10.5114/aoms/157308. PMID: 37034510; PMCID: PMC10074318.

Efficacy of topical tofacitinib 2% cream in the treatment of nail lichen planus.Iorizzo M., Indian Journal of Dermatology, Venereology and Leprology.:1-2.JAK Inhibitors and Inflammatory Nail Disorders: A Systematic Review of Clinical Outcomes and Therapeutic Potential.Iorizzo M, Sechi A, Neubauer ZJ, Zhou M, Lipner SR., American Journal of Clinical Dermatology. 2025 Apr 23:1-2.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Right Ventricular Dysfunction and Adverse Clinical Outcomes in Peripartum Cardiomyopathy: A Meta-Analysis.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Clinical Outcomes of Ezetimibe Plus Statins in Patients With Lower Extremity Artery Disease.

In this episode of the NCS Podcast Currents series, host Lauren Koffman, DO, MS, speaks with Camilo Espinosa-Jovel, MD, and Clio Rubinos, MD, MS, FACNS, about their recent Currents article on the Seizure Code strategy. They share how their collaboration began across continents, the origins of the seizure code and the importance of recognizing and treating urgent epileptic seizures before they progress. The discussion covers barriers faced in lower-resource settings, the steps involved in creating and implementing a protocol and the measurable improvements in treatment times and patient outcomes. They also reflect on how similar approaches could be adapted within U.S. hospitals to improve care for patients with seizures. To read the full article, visit Currents: Seizure Code Strategy: Improving Treatment Times and Clinical Outcomes in Patients With Urgent Epileptic Seizures The views expressed on the NCS Podcast are solely those of the hosts and guests and do not necessarily reflect the opinions or official positions of the Neurocritical Care Society.

Guest: Ann Klopp, M.D., Ph.D. The recent NRG0238 trial evaluated whether adding chemotherapy to radiation improves outcomes in patients with localized endometrial cancer recurrences. Hear from Dr. Ann Klopp as she explains the findings and how they could shift practice patterns for patient care. Dr. Klopp is a Professor of Radiation Oncology, the Director of Brachytherapy, and the leader of the gynecologic section in the Department of Radiation Oncology at The University of Texas MD Anderson Cancer Center in Houston.

Nutritionist Leyla Muedin discusses the critical role of mitochondrial health throughout the lifespan, citing Dr. Jeffrey Bland's insights on mitochondria as a cornerstone of 21st-century health. The episode explores the benefits of ketosis and the ketogenic diet, particularly in supporting neurological health and conditions like epilepsy, Alzheimer's, and multiple sclerosis. Leyla highlights how ketogenic diets stimulate mitochondrial biogenesis and improve mitochondrial function while addressing potential contraindications for specific populations. The importance of a functional medicine approach and personalized interventions is emphasized for optimal health outcomes.

Interview with Margaret Infeld, MD, MS, author of Clinical Outcomes With Personalized Accelerated Physiologic Pacing in Heart Failure With Preserved Ejection Fraction: Follow-Up of the myPACE Trial. Hosted by Robert Bonow, MD. Related Content: Clinical Outcomes With Personalized Accelerated Physiologic Pacing in Heart Failure With Preserved Ejection Fraction

Interview with Margaret Infeld, MD, MS, author of Clinical Outcomes With Personalized Accelerated Physiologic Pacing in Heart Failure With Preserved Ejection Fraction: Follow-Up of the myPACE Trial. Hosted by Robert Bonow, MD. Related Content: Clinical Outcomes With Personalized Accelerated Physiologic Pacing in Heart Failure With Preserved Ejection Fraction

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Suture-Mediated Patent Fossa Ovalis Closure: Late Clinical Outcomes and Predictors of Technical Success.

Joseph Mikhael, MD, and Surbhi Sidana, MD, discuss the importance of balancing treatment intervals, managing side effects, and maximizing quality of life in multiple myeloma patients. Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/1002713. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals. Resources Acyclovir Prophylaxis Against Varicella Zoster Virus Reactivation in Multiple Myeloma Patients Treated With Bortezomib-Based Therapies: A Retrospective Analysis of 100 Patients https://pubmed.ncbi.nlm.nih.gov/22222250/ Monitoring, Prophylaxis, and Treatment of Infections in Patients With MM Receiving Bispecific Antibody Therapy: Consensus Recommendations From an Expert Panel https://pubmed.ncbi.nlm.nih.gov/37528088/ Characterization of Dysgeusia and Xerostomia in Patients With Multiple Myeloma Treated With the T-Cell Redirecting GPRC5D Bispecific Antibody Talquetamab https://pubmed.ncbi.nlm.nih.gov/38092979/ Idecabtagene Vicleucel for Relapsed/Refractory Multiple Myeloma: Real-World Experience From the Myeloma CAR T Consortium https://pubmed.ncbi.nlm.nih.gov/36623248/ Incidence, Prognostic Impact and Clinical Outcomes of Renal Impairment In Patients With Multiple Myeloma: A Population-Based Registry https://pubmed.ncbi.nlm.nih.gov/31773154/ International Myeloma Working Group https://www.myeloma.org/international-myeloma-working-group IMWG Scientific and Working Committees https://www.myeloma.org/international-myeloma-working-group/imwg-scientific-working-committees

Five articles from the August 2025 issue summarized in five minutes, with the addition of a brief editorial commentary. The 5-in-5 feature is designed to give readers an overview of articles that may pique their interest and encourage more detailed reading. It may also be used by busy readers who would prefer a brief audio summary in order to select the articles they want to read in full. The featured articles this month are, “Spinopelvic Characteristics as Predictors of Cam Morphology: A 2-Year Follow-up of Elite Adolescent Soccer Players,” “Clinical Outcomes and Sports Participation After the Modified Broström Procedure in Children and Adolescents With Chronic Lateral Ankle Instability: A 5- to 10-Year Follow-up of 111 Cases,” “Introducing “Delta Angle” of Posterior Tibial Slope and Its Impact on ACL Reconstruction Failures: A Regression Analysis of 1174 Patients,” “Comparison of Snowman and Single-Plug Circular Osteochondral Allograft Transplantation Techniques for Similarly Sized Defects: A Matched Cohort Analysis,” and “Arthroscopic Bankart Repair Versus Immobilization for a First Episode of an Anterior Shoulder Dislocation Before the Age of 25 Years: A Randomized Controlled Trial With 6-Year Follow-up.” Click here to read the articles.

Este episódio tem papel duplo: prestar utilidade pública e reforçar a campanha #TodosPeloPirulla - participe você também, contribuindo para a recuperação do amigo, divulgador científico e youtuber Pirulla: vakinha.com.br/vaquinha/pirullaConfira o papo entre o leigo curioso, Ken Fujioka, e o cientista PhD, Altay de Souza.>> OUÇA (59min 59s)*Naruhodo! é o podcast pra quem tem fome de aprender. Ciência, senso comum, curiosidades, desafios e muito mais. Com o leigo curioso, Ken Fujioka, e o cientista PhD, Altay de Souza.Edição: Reginaldo Cursino.http://naruhodo.b9.com.br* APOIO: NORDVPNSe você escuta o Naruhodo há algum tempo, sabe que eu trabalho muito remotamente.Isso quer dizer que eu acabo usando muitos wifis públicos. Ou mesmo wifis privados, mas sobre os quais eu não tenho controle. E isso expõe dados meus, tais como senhas, números de cartão de crédito… E até mesmo minha privacidade sobre por onde eu estou navegando.Também quer dizer que, em algumas ocasiões, eu estou num país em que eu não posso acessar o conteúdo que está hospedado em outro país, por algum tipo de restrição técnica.Ou seja: perrengues da vida digital.É pra esses momentos todos que eu uso uma VPN, um serviço que protege sua conexão com a Internet.Mas não qualquer VPN: eu uso a NordVPN. Ela é fácil de instalar. fácil de usar e eu já confio por experiência própria.Por isso te convido a experimentar também a NordVPN com um desconto especial para ouvintes Naruhodo - e, se não ficar satisfeito, pode pedir seu reembolso garantido de 30 dias.É só acessar: https://nordvpn.com/naruhodoNordVPN, a VPN nº 1 de 2025 segundo a TechRadar.*APOIO: INSIDERIlustríssima ouvinte, ilustríssimo ouvinte do Naruhodo,Chegamos mais uma vez no momento INSIDER. E hoje eu quero compartilhar com você uma experiência pessoal.Eu sou relativamente minimalista em meu guarda-roupas: 70% das minhas peças são pretas, 90% delas são lisas.E meu estilo é bem informal: a roupa que eu uso no dia a dia não é tão diferente assim da roupa pra sair.Por isso a INSIDER combinou tanto comigo: ela me proporciona informalidade com sofisticação.Tecido encorpado e cortes modernos, que trazem um caimento perfeito. Peças que eu não preciso passar, que não marcam, que não ficam com mau cheiro - e, principalmente, peças que duram.Estilo despojado, sim, mas sempre com cara de novo. Minha vida fica mais prática e eu fico mais bem vestido.Então, fica aqui meu convite: experimente INSIDER você também e aproveite o desconto de 15% para ouvintes do NARUHODOPara isso, o jeito mais fácil é usar o endereço: creators.insiderstore.com.br/NARUHODOOu clicar no link da descrição deste episódio: o cupom NARUHODO será aplicado automaticamente no carrinho.INSIDER, inteligência em cada escolha.#InsiderStore*REFERÊNCIASVaquinha do Pirulahttps://www.vakinha.com.br/vaquinha/pirullaPathophysiology of Ischemic Strokehttps://link.springer.com/chapter/10.1007/978-981-10-5804-2_4Effects of aspirin on risk and severity of early recurrent stroke after transient ischaemic attack and ischaemic stroke: time-course analysis of randomised trialshttps://pmc.ncbi.nlm.nih.gov/articles/PMC5321490/Cryptogenic stroke: time to determine aetiologyhttps://www.jthjournal.org/article/S1538-7836(22)10551-9/fulltextSummary of evidence-based guideline: Periprocedural management of antithrombotic medications in patients with ischemic cerebrovascular diseasehttps://pmc.ncbi.nlm.nih.gov/articles/PMC3716407/A systematic review and synthesis of global stroke guidelines on behalf of the World Stroke Organizationhttps://journals.sagepub.com/doi/full/10.1177/17474930231156753Dental Management Considerations for the Cardiac Patienthttps://onlinelibrary.wiley.com/doi/abs/10.1111/scd.70048?casa_token=ttBLDqLWGt0AAAAA%3AO1oMHKDSRIFa3VmyQGU7DdblutxTUbu9ryEvRqBoJLUx8AqJhMBvKcnElH5XY2tE88GU3PdTEp8wEx0tClinical diagnosis of stroke subtypes https://www.uptodate.com/contents/clinical-diagnosis-of-stroke-subtypesWorld Stroke Organization: Global Stroke Fact Sheet 2025https://journals.sagepub.com/doi/full/10.1177/17474930241308142Artificial intelligence in stroke rehabilitation: From acute care to long-term recoveryhttps://www.sciencedirect.com/science/article/pii/S0306452225002180?casa_token=NzPfRaWoZOAAAAAA:GEmB6wj1KbQA8dw79yZOaOAnIy416QI0UpvqQlDrz6cCYDgoT7CQ-xwikHLwD8UkNhLlwLhaf40Air pollution and stroke: Short-term exposure's varying effects on stroke subtypeshttps://www.sciencedirect.com/science/article/pii/S0147651325006323Hyperacute stroke care–What's new?https://journals.sagepub.com/doi/full/10.1177/17474930251348387?casa_token=hH0neB-v_E0AAAAA%3A6C706lwrzHGSeV8xAdAUMNudTMYecSZUOVTxCCKUpUfGN0pv7mezUIUcprlNfTQ8JirCLmi7CKlPDgAdvances in Epidemiology, Outcomes, and Population Science in 2024https://www.ahajournals.org/doi/abs/10.1161/STROKEAHA.125.049886Chain mediating effect of frailty and depression between nutrition and quality of life in elderly stroke patients https://www.tandfonline.com/doi/abs/10.1080/13548506.2025.2502843Telemedicine and Post-Acute Care Demands: Evidence from Stroke Patientshttps://aisel.aisnet.org/pacis2025/ishealthcare/ishealthcare/17/The global prevalence of oropharyngeal dysphagia in different populations: a systematic review and meta-analysishttps://link.springer.com/article/10.1186/s12967-022-03380-0Stroke–heart syndrome: clinical presentation and underlying mechanismshttps://www.thelancet.com/journals/laneur/article/PIIS1474-4422(18)30336-3/abstractBrain–heart interaction after acute ischemic strokehttps://link.springer.com/article/10.1186/s13054-020-02885-8Stroke-Heart Syndrome: Incidence and Clinical Outcomes of Cardiac Complications Following Strokehttps://www.ahajournals.org/doi/full/10.1161/STROKEAHA.121.037316Impact of OSA on cardiovascular events after coronary artery bypass surgeryhttps://pubmed.ncbi.nlm.nih.gov/25612013/Sleep apnea prevalence and severity after coronary revascularization versus no intervention: a systematic review & meta-analysishttps://link.springer.com/article/10.1007/s11325-024-03164-4Obstructive Sleep Apnea and Outcomes in Cardiac Surgery: A Systematic Review with Meta-Analytic Synthesis (PROSPERO CRD420251049574)https://www.mdpi.com/2227-9059/13/7/1579Guidelines for the Prevention of Stroke in Women A Statement for Healthcare Professionals From the American Heart Association/American Stroke Associationhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10152977/Clipe da Música Prevenção Contra o AVC 2017https://www.youtube.com/watch?v=F1GjcMJTdeQNaruhodo #236 - Por que temos dor de cabeça?https://www.youtube.com/watch?v=q8FtXVlSz1INaruhodo #264 - Por que é importante conhecer nosso colesterol?https://www.youtube.com/watch?v=5D3ezsGM_5sNaruhodo #256 - Por que roncamos?https://www.youtube.com/watch?v=SfJH_F2GsI4Naruhodo #162 - Por que acontece o nocaute?https://www.youtube.com/watch?v=_UmiDEjZmfcNaruhodo #163 - O que a anestesia desliga no nosso corpo?https://www.youtube.com/watch?v=6IoMagNybTINaruhodo #217 - Por que algumas pessoas tremem?https://www.youtube.com/watch?v=K7KLyBBnK_Q*APOIE O NARUHODO!O Altay e eu temos duas mensagens pra você.A primeira é: muito, muito obrigado pela sua audiência. Sem ela, o Naruhodo sequer teria sentido de existir. Você nos ajuda demais não só quando ouve, mas também quando espalha episódios para familiares, amigos - e, por que não?, inimigos.A segunda mensagem é: existe uma outra forma de apoiar o Naruhodo, a ciência e o pensamento científico - apoiando financeiramente o nosso projeto de podcast semanal independente, que só descansa no recesso do fim de ano.Manter o Naruhodo tem custos e despesas: servidores, domínio, pesquisa, produção, edição, atendimento, tempo... Enfim, muitas coisas para cobrir - e, algumas delas, em dólar.A gente sabe que nem todo mundo pode apoiar financeiramente. E tá tudo bem. Tente mandar um episódio para alguém que você conhece e acha que vai gostar.A gente sabe que alguns podem, mas não mensalmente. E tá tudo bem também. Você pode apoiar quando puder e cancelar quando quiser. O apoio mínimo é de 15 reais e pode ser feito pela plataforma ORELO ou pela plataforma APOIA-SE. Para quem está fora do Brasil, temos até a plataforma PATREON.É isso, gente. Estamos enfrentando um momento importante e você pode ajudar a combater o negacionismo e manter a chama da ciência acesa. Então, fica aqui o nosso convite: apóie o Naruhodo como puder.bit.ly/naruhodo-no-orelo

In the SCENT trial, researchers investigated the effects of the Surpass flow diverter system for treating wide-necked aneurysms. Five-year results of this trial have recently been published in JNIS, presenting the safety and effectiveness outcomes of treatment with the Surpass Streamline flow diverter system. The study analyses the rates of aneurysm occlusion and adverse events.   Editor-in-Chief of JNIS, Dr. Felipe C. Albuquerque, interviews Dr. Philip Meyers¹, author of the paper: Five-year results of the SCENT trial with Surpass flow diverters to treat large or giant wide-neck aneurysms   1. Radiology and Neurological Surgery, Columbia University, New York, USA   Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

Welcome to Overtime with the Sports Docs! On each of these mini episodes, we chat about a new article or new surgical technique in the field of sports medicine. We'll give you our quick take on the most recent data and how this data will be impacting our practice.Today, we're talking about posterior cruciate ligament injuries – specifically, surgical treatment; including reconstruction technique and graft choice. We'll be reviewing an article published this month in AJSM titled, “Single-Bundle Autografts Outperform Single-Bundle Achilles Allograft in PCL Reconstruction in Terms of Posterior Tibial Translation and Clinical Outcomes, but No Differences Exist Between Double-Bundle Grafts.”LaPrade PCL Stress Test: https://drrobertlaprademd.com/pcl-stress-radiograph-technique-edina-egan-mn/

In this episode of Quah (Q & A), Sal, Adam & Justin answer four Pump Head questions drawn from last Sunday's Quah post on the @mindpumpmedia Instagram page.  Mind Pump Fit Tip: The 5 best diets for ANY goal. (1:38) The MOST common mistake people make with fitness & diet. (19:53) The BEST recovery tool to manage stress. (31:03) Terrible/harming tactics by mainstream media. (35:27) Creatine and depression. (41:27) The history of ginseng. (44:12) The conspiracy theory behind art. (48:36) Kids say the darndest things. (53:12) Mind Pump Recommends You Can't Ask That on Netflix. (56:21) Train the Trainer 3-Part Bonus Series dropping May 19th! (1:00:47) #Quah question #1 – What do you guys do to keep up strength when resting an injury? (1:01:37) #Quah question #2 – What should you do if you are reverse dieting but see weight gain? (1:04:17) #Quah question #3 – Will taking NSAID's to treat an acute injury completely negate gains from strength training? (1:06:04) #Quah question #4 – How do you see AI affecting the fitness industry? What are the pros and cons that can come of its involvement for trainers, nutrition coaches and their clients? (1:09:26) Related Links/Products Mentioned Visit Eight Sleep for an exclusive offer for Mind Pump Listeners! ** Use the code MINDPUMP to get $350 off your very own Pod 5 Ultra. The best part is that you still get 30 days to try it at home and return it if you don't like it - - Shipping to many countries worldwide. ** Visit Joy Mode for an exclusive offer for Mind Pump listeners! ** Enter MINDPUMP at checkout for 20% off your first order. ** May Special: MAPS 15 Performance or RGB Bundle 50% off! ** Code MAY50 at checkout ** Labs - Stephen Cabral Why Are Americans So Obsessed With Protein? Blame MAGA Creatine Supplementation in Depression: A Review of Mechanisms, Efficacy, Clinical Outcomes, and Future Directions Mind Pump #2530: Why All Women Should Take Creatine The history of ginseng in the management of erectile dysfunction in ancient China (3500-2600 BCE) Watch You Can't Ask That - Netflix Train the Trainer Webinar Series – 3 Part Bonus Series  Visit Hiya for an exclusive offer for Mind Pump listeners! ** Receive 50% off your first order ** Mechanisms and applications of the anti-inflammatory effects of photobiomodulation Mind Pump Podcast – YouTube Mind Pump Free Resources People Mentioned Mikhaila Peterson (@mikhailapeterson) Instagram Dr. Stephen Cabral (@stephencabral) Instagram Benjamin Bikman (@benbikmanphd) Instagram  

AABP Executive Director Dr. Fred Gingrich reviews a paper published in The Bovine Practitioner with the first author Madeline Mancke from Kansas State University. The objective of this study was to determine potential associations between Cardiac Troponin I (cTnI) serum concentration of cattle at initial bovine respiratory disease (BRD) treatment with the risk of retreatment or mortality at 60 days. BRD is the most significant disease in beef cattle and is a major cause of morbidity and mortality. Developing prognostic tools may be valuable for managing individual cases. cTnI is a protein that is released into the circulatory system after myocardial damage and may be useful as a biomarker for prognostication of BRD cases. Mancke walks through the results of the paper which demonstrated that 8/318 samples had high cTnI levels and animals with high cTn1 concentrations had a significantly greater probability of not finishing the 60-day post-enrollment period. Cattle with high cardiac troponin concentrations at initial BRD treatment were more likely to have negative clinical outcomes but, in this study, very few animals had high cTnI levels. Mancke provides information about potential future research opportunities to better manage BRD cases in the feedyard.  The Bovine Practitioner is the peer-reviewed journal published by AABP. The journal publishes original research, case studies, review articles and case studies that are intended to provide information to the practicing cattle veterinarian. The journal is available open-access online and print volumes are available for purchase. There are no publication fees for authors and the peer review and submission process is managed online. Find the journal at this link.  Evaluation of cardiac troponin I as a predictor of clinical outcomes in cattle treated for bovine respiratory disease (BRD) in commercial feedyards. Bov Pract. 2025;59(1), 24-28. https://doi.org/10.21423/bpj20259053