Podcast appearances and mentions of scott sharkey

Ever wish that every other person on the planet would vanish in a puff of smoke? Feeling that way more than usual lately? So have I! And so has Scott Sharkey, who wanders in from the wastelands to talk about The Quiet Earth, the hugely influential New Zealand classic about what it would be like to be the literal last man on Earth (and then suddenly not be).

I found Scott Sharkey wondering in the desert, put a microphone in front of him, and had him talk about the lesser-known Vincent Price/John Carradine horror anthology The Monster Club. This swan song of British horror anthologies is goofy as hell. Find out what a humgoo is and why Shaddocks should NEVER WHISTLE. And hear some great (and horrible) monster-themed rock and/or roll!

Nadia Oxford, Shivam Bhatt, and Scott Sharkey are joined by legendary developers Paul Riche and Fred Ford in a discussion about Star Control. What makes this RPG-adventure pioneer so compelling and popular? What comes next for the Ur-Quan Masters? Retronauts is made possible by listener support through Patreon! Support the show to enjoy ad-free early access, better audio quality, and great exclusive content. Learn more at http://www.patreon.com/retronauts

By the fetid breath of Dogar and Kazon! Nadia Oxford, Shivam Bhatt, and Scott Sharkey have traveled to this insignificant quadrant of the galaxy to evangelize about two games that changed space adventure games forever: Star Control I & II. Cover art by John Pading. Edits by Greg Leahy. Retronauts is made possible by listener support through Patreon! Support the show to enjoy ad-free early access, better audio quality, and great exclusive content. Learn more at http://www.patreon.com/retronauts

In this podcast, Dr. Scott Sharkey, senior consulting cardiologist with Minneapolis Heart Institute, provides a discussion on cardiomyopathy and more specifically Takotsubo syndrome. Enjoy the podcast! Objectives:     Upon completion of this podcast, participants should be able to: Describe how Takotsubo cardiomyopathy was discovered. Differentiate the diagnostic criteria for Takotsubo cardiomyopathy from other cardiology related conditions. Identify treatment options for Takotsubo cardiomyopathy. CME credit is only offered to Ridgeview Providers & Allied Health Staff for this podcast activity. Complete and submit the online evaluation form, after viewing the activity.  Upon successful completion of the evaluation, you will be e-mailed a certificate of completion within approximately 2 weeks.  You may contact the accredited provider with questions regarding this program at  rmccredentialing@ridgeviewmedical.org. Click on the following link for your CME credit: CME Evaluation: "Achin' Breaking Hearts: Takotsubo Syndrome w/Dr. Scott Sharkey" (**If you are listening to the podcasts through iTunes on your laptop or desktop, it is not possible to link directly with the CME Evaluation for unclear reasons. We are trying to remedy this. You can, however, link to the survey through the Podcasts app on your Apple and other smart devices, as well as through Spotify, Stitcher and other podcast directory apps and on your computer browser at these websites. We apologize for the inconvenience.)  DISCLOSURE ANNOUNCEMENT  The information provided through this and all Ridgeview podcasts as well as any and all accompanying files, images, videos and documents is/are for CME/CE and other institutional learning and communication purposes only and is/are not meant to substitute for the independent medical judgment of a physician, healthcare provider or other healthcare personnel relative to diagnostic and treatment options of a specific patient's medical condition; and are property/rights of Ridgeview Medical Center & Clinics.  Any re-reproduction of any of the materials presented would be infringement of copyright laws.  It is Ridgeview's intent that any potential conflict should be identified openly so that the listeners may form their own judgments about the presentation with the full disclosure of the facts. It is not assumed any potential conflicts will have an adverse impact on these presentations. It remains for the audience to determine whether the speaker’s outside interest may reflect a possible bias, either the exposition or the conclusions presented. Ridgeview's CME planning committee members and presenter(s) have disclosed they have no significant financial relationship with a pharmaceutical company and have disclosed that no conflict of interest exists with the presentation/educational event. SHOW NOTES: CHAPTER 1: Cardiomyopathy. According to Dr. Sharkey, it is a general term for cardiac muscle disease, often times of unknown cause. Usually it refers to a dilated, poorly, contracting heart. Though it's also been called stress cardiomyopathy, Takotsubo does not behave like most cardiomyopathies. It's a microcirculatory disease, causing a stunned myocardium similar to an acute myocardial infarction, but with non-obstructive epicardial coronary arteries. Dr. Sharkey and his colleagues first noticed this phenomenon in patients with myocardial infarction that showed deep T wave inversions on EKG, and initial ECHOs with ejection fractions of 25-30%. Weeks later, these injuries would resolve, findings they attributed to a stunned myocardium. This phenomenon was then seen in a patient with a TBI, who again had a deep T wave inversion, and a large left ventricular regional wall motion abnormality with normal coronary arteries. The regional wall motion abnormality, again, resolved. These findings were noted in 20 similar cases that were then published in 1998. Though to note, this same syndrome was also present in the Japanese literature at this time. Later, it was noted patients were developing these symptoms not just from severe illness or trauma, but also from deeply emotional situations. This led to a write-up in Circulation in 2005, which received the 'Paper of the Year' award. From the early days to now, Dr. Sharkey went from seeing three to four patients per year with Takotsubo, to present day, one to two patients per week. The Minneapolis Heart Institute Foundation has done, and continues to do robust research on Takotsubo, noting that there is a subset of vulnerable patients that actually have recurrences of Takotsubo., They have also been able to study specific triggers for Takotsubo, like drug use, pheochromocytoma and critical illness in general. CHAPTER 2: Triggers for Takotsubo. As mentioned before, drug use, pheochromocytoma or critical illness are causes, but really any physical illness as well as any emotional stress are triggers for this syndrome. Death of a spouse is a good example of an emotional trigger, though as exemplified in the discussion, it can be any emotional situation. Teasing out the patient's history and the specific precipitation event is an art form. The autonomic nervous system is implicated here. Catecholamine levels are very elevated in these patients, as opposed to lower levels seen in acute MI patients. Pheochromocytoma and accidental overdose of epinephrine will cause this as well. The pathophysiology of the event is still being researched. It's postulated that this is all caused by vasospasms of the circulation or direct myocardial injury due to the catecholamine excess. It's presumed that effects occur on micro-circulatory level, and any disruption in blood flow is brief, less than 15-20 minutes, enough to raise serum troponins and cause wall motion abnormality. The involvement is circumferential, so the ECG findings are more diffuse. EKG changes include ST segment elevation in about 40% of patients. Otherwise T wave inversion is often seen, but is a later development. ST depression is not generally seen in Takotsubo, and would instead indicate a coronary artery occlusion. Echo findings show a classic, distinctive finding: poor contractility or akineses from the mid-heart to the apex, while the base of the heart is hypercontractile. Also called apical ballooning, the apex can be seen ballooning outward on echocardiograms. This is what is reminiscent of a Japanese clay pot, octopus trap, aka Takotsubo. And yes, the name is most certainly credited to the Japanese. CHAPTER 3: When a patient presents with an acute cardiac event that looks like Takotsubo, the patients still must undergo coronary angiogram to exclude a coronary occlusion. Cardiac echo and cardiac MRI are used to help diagnose this disease. Beta blockers and ACE inhibitors are used early on in treatment, but Dr. Sharkey suspects that patients would probably recover without them. The reality is, most of these patients get better. The myocardium, in the setting to Takotsubo, should recover. A process that usually takes one to two weeks. Anti-platelets do not play a role here, but anticoagulants are often given until the myocardium has recovered to prevent a small risk of left ventricular thrombus. Left ventricular outflow tract obstruction is a complicating factor in Takotsubo. Many of these patients are middle aged to older women, and have basal septal hypertrophy. This exacerbates, the outflow obstruction, which causes hypotension and shock in Takotsubo, 15-20% of the time. The left ventricular outflow obstruction should resolve with the resolution of Takotsubo. As mentioned, Takotsubo can have a recurrent phenomenon, and remarkably, these patients all recover their heart function. Curiously, the precipitating cause for these patients tends to be emotional. Though used in the initial treatment, beta blockers are not prescribed long-term for Takotsubo patients. In fact, Dr. Sharkey found that 30% of patients with a Takotsubo event were already on beta blockers, and 80% of those who have had recurrent Takotsubo were already on beta blockers and ACE inhibitors. CHAPTER 4: Patient presentation: Patients can present with chest discomfort and/or shortness of breath, much like an acute MI patient. They can also present with an acute concern of another nature. Dr. Sharkey gave the example of a patient presenting with a pasteurella multocida infection causing an airway obstruction. The patient's ongoing hypotension led to further work up and diagnosis of Takotsubo. Takotsubo patients can also be discovered during inpatient stays when incidental ECG wave form changes, troponin elevation, tachycardia, and/or hypotension are noted. About 10% of Takotsubo patient's develop cardiogenic shock. Most survive their ICU stay, even if advanced treatment, like intra-aortic balloon pumps or ECMO are required. For the critically ill, where beta blocker use is contraindicated in the light hypotension, Dr. Sharkey preferred choice of vasopressin followed by phenylephrine. Fortunately, patients recover from Takotsubo. However, malignant arrhythmias and cardiac arrest can happen. Patients are counseled to present to emergency care if their symptoms ever return. Thank-you for listening.

It's hard to believe, but the podcast devoted to discussing old games is now old itself! On this special live episode of Retronauts, join Bob Mackey, Jeremy Parish, Chris Kohler, and special guest Scott Sharkey as the crew discusses a decade spent stuck in the past. (Special thanks to twitter user @RPeavyhouse for the cover photo!) Be sure to visit our blog at Retronauts.com, and check out our partner site, USgamer, for more great stuff. And if you'd like to send a few bucks our way, head on over to our Patreon page!

Retronauts alumnus Scott Sharkey returns from his 40 weeks of wandering in the desert to join us for a look back at the history of Atari, from the early days of the American arcade through the glory times of the 2600 and on to the sad dissolution that followed. Jeremy Parish hosts, with Bob Mackey on play-by-play and Ray on color.

Sega's more than just Sonic, you know; over the years, the famed Japanese developer tried (and ultimately failed) to launch several properties that are still near and dear to our hearts. Join Bob Mackey, Jose Otero, and Scott Sharkey as they explore Jet Set Radio, Panzer Dragoon, and Shenmue, and catch up on a hefty backlog of listener mail (but you can skip to 31:54 if you don’t care about that).

Sega's more than just Sonic, you know; over the years, the famed Japanese developer tried (and ultimately failed) to launch several properties that are still near and dear to our hearts. Join Bob Mackey, Jose Otero, and Scott Sharkey as they explore Jet Set Radio, Panzer Dragoon, and Shenmue, and catch up on a hefty backlog of listener mail (but you can skip to 31:54 if you don’t care about that).

Sega's more than just Sonic, you know; over the years, the famed Japanese developer tried (and ultimately failed) to launch several properties that are still near and dear to our hearts. Join Bob Mackey, Jose Otero, and Scott Sharkey as they explore Jet Set Radio, Panzer Dragoon, and Shenmue, and catch up on a hefty backlog of listener mail (but you can skip to 31:54 if you don’t care about that).

Sega's more than just Sonic, you know; over the years, the famed Japanese developer tried (and ultimately failed) to launch several properties that are still near and dear to our hearts. Join Bob Mackey, Jose Otero, and Scott Sharkey as they explore Jet Set Radio, Panzer Dragoon, and Shenmue, and catch up on a hefty backlog of listener mail (but you can skip to 31:54 if you don’t care about that).

For the sake of closure, Retronauts host Bob Mackey employs the help of Sam Claiborn, Scott Sharkey, and Marty Sliva to discuss two decades of Simpsons games. Will they be crantastic, cromulent, craptacular, or have us shouting boo-urns until our throats are sore? If you managed to decipher the previous sentence, this is the podcast for you.

For the sake of closure, Retronauts host Bob Mackey employs the help of Sam Claiborn, Scott Sharkey, and Marty Sliva to discuss two decades of Simpsons games. Will they be crantastic, cromulent, craptacular, or have us shouting boo-urns until our throats are sore? If you managed to decipher the previous sentence, this is the podcast for you.

For the sake of closure, Retronauts host Bob Mackey employs the help of Sam Claiborn, Scott Sharkey, and Marty Sliva to discuss two decades of Simpsons games. Will they be crantastic, cromulent, craptacular, or have us shouting boo-urns until our throats are sore? If you managed to decipher the previous sentence, this is the podcast for you.

For the sake of closure, Retronauts host Bob Mackey employs the help of Sam Claiborn, Scott Sharkey, and Marty Sliva to discuss two decades of Simpsons games. Will they be crantastic, cromulent, craptacular, or have us shouting boo-urns until our throats are sore? If you managed to decipher the previous sentence, this is the podcast for you.

'Tis the season... for scary games. (Hey, there can be two seasons.) Join Retronauts Bob Mackey, Jose Otero, and Scott Sharkey as they divulge secret fears and field calls on the subject of games likely to coax the tar out of your many orifices.

'Tis the season... for scary games. (Hey, there can be two seasons.) Join Retronauts Bob Mackey, Jose Otero, and Scott Sharkey as they divulge secret fears and field calls on the subject of games likely to coax the tar out of your many orifices.

'Tis the season... for scary games. (Hey, there can be two seasons.) Join Retronauts Bob Mackey, Jose Otero, and Scott Sharkey as they divulge secret fears and field calls on the subject of games likely to coax the tar out of your many orifices.

'Tis the season... for scary games. (Hey, there can be two seasons.) Join Retronauts Bob Mackey, Jose Otero, and Scott Sharkey as they divulge secret fears and field calls on the subject of games likely to coax the tar out of your many orifices.

The PS2 is somehow on the brink of its 11th birthday, which makes us all feel very old. Join Retronauts host Bob Mackey and guests Scott Sharkey and Ray Barnholt as they discuss Sony's past console with listeners and age audibly.

The PS2 is somehow on the brink of its 11th birthday, which makes us all feel very old. Join Retronauts host Bob Mackey and guests Scott Sharkey and Ray Barnholt as they discuss Sony's past console with listeners and age audibly.

The PS2 is somehow on the brink of its 11th birthday, which makes us all feel very old. Join Retronauts host Bob Mackey and guests Scott Sharkey and Ray Barnholt as they discuss Sony's past console with listeners and age audibly.

The PS2 is somehow on the brink of its 11th birthday, which makes us all feel very old. Join Retronauts host Bob Mackey and guests Scott Sharkey and Ray Barnholt as they discuss Sony's past console with listeners and age audibly.

With the release of Deus Ex: Human Revolution on the horizon, Retronauts host Bob Mackey sits down with Thierry "Scooter" Nguyen, Ryan Winterhalter, Scott Sharkey, and Mike Nelson to talk about Ion Storm's groundbreaking franchise -- and since Metroid's 25th anniversary just passed us by, there's talk of that as well. This episode truly has something for everyone, except for people who don’t care about Deus Ex or Metroid.

With the release of Deus Ex: Human Revolution on the horizon, Retronauts host Bob Mackey sits down with Thierry "Scooter" Nguyen, Ryan Winterhalter, Scott Sharkey, and Mike Nelson to talk about Ion Storm's groundbreaking franchise -- and since Metroid's 25th anniversary just passed us by, there's talk of that as well. This episode truly has something for everyone, except for people who don’t care about Deus Ex or Metroid.

With the release of Deus Ex: Human Revolution on the horizon, Retronauts host Bob Mackey sits down with Thierry "Scooter" Nguyen, Ryan Winterhalter, Scott Sharkey, and Mike Nelson to talk about Ion Storm's groundbreaking franchise -- and since Metroid's 25th anniversary just passed us by, there's talk of that as well. This episode truly has something for everyone, except for people who don’t care about Deus Ex or Metroid.

With the release of Deus Ex: Human Revolution on the horizon, Retronauts host Bob Mackey sits down with Thierry "Scooter" Nguyen, Ryan Winterhalter, Scott Sharkey, and Mike Nelson to talk about Ion Storm's groundbreaking franchise -- and since Metroid's 25th anniversary just passed us by, there's talk of that as well. This episode truly has something for everyone, except for people who don’t care about Deus Ex or Metroid.

Chrono Trigger arrived on Virtual Console last week, and that's pretty much all the excuse Jeremy Parish, Jose Otero, and Scott Sharkey needed to open the phone lines and talk about the game. Featuring the voice of Lavos!

Chrono Trigger arrived on Virtual Console last week, and that's pretty much all the excuse Jeremy Parish, Jose Otero, and Scott Sharkey needed to open the phone lines and talk about the game. Featuring the voice of Lavos!

Chrono Trigger arrived on Virtual Console last week, and that's pretty much all the excuse Jeremy Parish, Jose Otero, and Scott Sharkey needed to open the phone lines and talk about the game. Featuring the voice of Lavos!

Chrono Trigger arrived on Virtual Console last week, and that's pretty much all the excuse Jeremy Parish, Jose Otero, and Scott Sharkey needed to open the phone lines and talk about the game. Featuring the voice of Lavos!

To commemorate the long-awaited return of director Yotsui "Isuke" Koucihi (courtesy of Moon Diver), Jeremy Parish, Sam Kennedy, and Scott Sharkey talk about his 1989 arcade classic Strider (and Strider's other, less classic iterations, too).

To commemorate the long-awaited return of director Yotsui "Isuke" Koucihi (courtesy of Moon Diver), Jeremy Parish, Sam Kennedy, and Scott Sharkey talk about his 1989 arcade classic Strider (and Strider's other, less classic iterations, too).

To commemorate the long-awaited return of director Yotsui "Isuke" Koucihi (courtesy of Moon Diver), Jeremy Parish, Sam Kennedy, and Scott Sharkey talk about his 1989 arcade classic Strider (and Strider's other, less classic iterations, too).

To commemorate the long-awaited return of director Yotsui "Isuke" Koucihi (courtesy of Moon Diver), Jeremy Parish, Sam Kennedy, and Scott Sharkey talk about his 1989 arcade classic Strider (and Strider's other, less classic iterations, too).

OH WHAT A SURPRISE. This week Scott Sharkey joins us to chat about life in the woods and why Sony sucks for leaving their service so vulnerable to attacks. Plus, Soundboard Chris and the rest of the gang talk about Call of Duty online in China and more Alan Wake. And Ballsrog gets hyped about Mass Effect 3.

OH WHAT A SURPRISE. This week Scott Sharkey joins us to chat about life in the woods and why Sony sucks for leaving their service so vulnerable to attacks. Plus, Soundboard Chris and the rest of the gang talk about Call of Duty online in China and more Alan Wake. And Ballsrog gets hyped about Mass Effect 3.

We celebrate both the existence of Colecovision and the merger of 1UP and IGN by dragging Scott Bromley and Sam Claiborn into the studio to talk all things Coleco with Jeremy Parish and Scott Sharkey. It's collaborative!

We celebrate both the existence of Colecovision and the merger of 1UP and IGN by dragging Scott Bromley and Sam Claiborn into the studio to talk all things Coleco with Jeremy Parish and Scott Sharkey. It's collaborative!

We celebrate both the existence of Colecovision and the merger of 1UP and IGN by dragging Scott Bromley and Sam Claiborn into the studio to talk all things Coleco with Jeremy Parish and Scott Sharkey. It's collaborative!

We celebrate both the existence of Colecovision and the merger of 1UP and IGN by dragging Scott Bromley and Sam Claiborn into the studio to talk all things Coleco with Jeremy Parish and Scott Sharkey. It's collaborative!

Jeremy Parish, Christian Nutt, and Scott Sharkey take to the phone lines and the world of Justin.tv to discuss Capcom's Mega Man X series with and in front of a live audience. Whatever we're fighting for, it appears to be a totally sweet cause.

Jeremy Parish, Christian Nutt, and Scott Sharkey take to the phone lines and the world of Justin.tv to discuss Capcom's Mega Man X series with and in front of a live audience. Whatever we're fighting for, it appears to be a totally sweet cause.

Jeremy Parish, Christian Nutt, and Scott Sharkey take to the phone lines and the world of Justin.tv to discuss Capcom's Mega Man X series with and in front of a live audience. Whatever we're fighting for, it appears to be a totally sweet cause.

Jeremy Parish, Christian Nutt, and Scott Sharkey take to the phone lines and the world of Justin.tv to discuss Capcom's Mega Man X series with and in front of a live audience. Whatever we're fighting for, it appears to be a totally sweet cause.

Everyone loves arcade games! At least, everyone who calls in to talk this episode. As long as you're referring to classic arcade games. With these caveats in mind, quarter up and listen to Jeremy Parish, Frank Cifaldi, Scott Sharkey, and Brandon Sheffield.

Everyone loves arcade games! At least, everyone who calls in to talk this episode. As long as you're referring to classic arcade games. With these caveats in mind, quarter up and listen to Jeremy Parish, Frank Cifaldi, Scott Sharkey, and Brandon Sheffield.

Everyone loves arcade games! At least, everyone who calls in to talk this episode. As long as you're referring to classic arcade games. With these caveats in mind, quarter up and listen to Jeremy Parish, Frank Cifaldi, Scott Sharkey, and Brandon Sheffield.

Everyone loves arcade games! At least, everyone who calls in to talk this episode. As long as you're referring to classic arcade games. With these caveats in mind, quarter up and listen to Jeremy Parish, Frank Cifaldi, Scott Sharkey, and Brandon Sheffield.

Dabbling in a brief bout of necromancy, Jeremy Parish grabs Frank Cifaldi, Scott Sharkey, and Chris Kohler to do a year-end roundup for 1971, '76, '81, '86 (and so forth) before letting the show return once again to the grave.

Dabbling in a brief bout of necromancy, Jeremy Parish grabs Frank Cifaldi, Scott Sharkey, and Chris Kohler to do a year-end roundup for 1971, '76, '81, '86 (and so forth) before letting the show return once again to the grave.

Dabbling in a brief bout of necromancy, Jeremy Parish grabs Frank Cifaldi, Scott Sharkey, and Chris Kohler to do a year-end roundup for 1971, '76, '81, '86 (and so forth) before letting the show return once again to the grave.

Dabbling in a brief bout of necromancy, Jeremy Parish grabs Frank Cifaldi, Scott Sharkey, and Chris Kohler to do a year-end roundup for 1971, '76, '81, '86 (and so forth) before letting the show return once again to the grave.

Somehow, Beastmaster and Master of the Universe make it on the show, starring Tina Sanchez and Scott Sharkey.

Somehow, Beastmaster and Master of the Universe make it on the show, starring Tina Sanchez and Scott Sharkey.

The bulk of the 1UP staff is gone this weekend, but Ray still pulls in Scooter and Scott Sharkey for this week's roundup. There's much to be discussed about subjects such as the possible StarCraft and BioShock movies (and many others), the new Xbox 360 controller, Nintendo's Mario All-Stars revival, plus new impressions of Call of Duty Black Ops and Sony's Move launch games.

The bulk of the 1UP staff is gone this weekend, but Ray still pulls in Scooter and Scott Sharkey for this week's roundup. There's much to be discussed about subjects such as the possible StarCraft and BioShock movies (and many others), the new Xbox 360 controller, Nintendo's Mario All-Stars revival, plus new impressions of Call of Duty Black Ops and Sony's Move launch games.

Tactical RPGs? Strategy RPGs? Whichever is the proper term, Kat, Jeremy, Ray and special guest Christian Nutt sit down to discuss the ups and downs of one of the nerdiest RPG subgenres. The crew also takes a look at the recently-released Ys Seven, but not before Travis Williams and Scott Sharkey stop by to share their thoughts on the recently-announced Neverwinter reboot by Cryptic. It's an episode so huge that we go ten full minutes over our usual runtime.

Tactical RPGs? Strategy RPGs? Whichever is the proper term, Kat, Jeremy, Ray and special guest Christian Nutt sit down to discuss the ups and downs of one of the nerdiest RPG subgenres. The crew also takes a look at the recently-released Ys Seven, but not before Travis Williams and Scott Sharkey stop by to share their thoughts on the recently-announced Neverwinter reboot by Cryptic. It's an episode so huge that we go ten full minutes over our usual runtime.

Host: Janet Wright, MD Guest: Scott Sharkey, MD Takotsubo, or stress-induced cardiomyopathy (also known as 'broken heart syndrome'), was first recognized in Japan in the 1990s. Acute emotional or physical stress trigger the condition, which mimics the symptoms of a myocardial infarction (or MI). How can physicians differentiate between stress-induced cardiomyopathy and a more conventional MI, and how is stress-induced cardiomyopathy treated? What characteristics might make a patient more susceptible to developing this condition? Our guest is Dr. Scott Sharkey, senior consulting cardiologist at Minneapolis Heart Institute and director of the Takotsubo cardiomyopathy research program at the Minneapolis Heart Institute Foundation in Minnesota, shares some of the key diagnostic tests for differentiating between stress-induced cardiomyopathy and conventional MI. How common is this condition, and how can we limit the effects of stress-induced cardiomyopathy? Dr. Janet Wright hosts. Produced in Cooperation with

Host: Janet Wright, MD Guest: Scott Sharkey, MD Takotsubo, or stress-induced cardiomyopathy (also known as 'broken heart syndrome'), was first recognized in Japan in the 1990s. Acute emotional or physical stress trigger the condition, which mimics the symptoms of a myocardial infarction (or MI). How can physicians differentiate between stress-induced cardiomyopathy and a more conventional MI, and how is stress-induced cardiomyopathy treated? What characteristics might make a patient more susceptible to developing this condition? Our guest is Dr. Scott Sharkey, senior consulting cardiologist at Minneapolis Heart Institute and director of the Takotsubo cardiomyopathy research program at the Minneapolis Heart Institute Foundation in Minnesota, shares some of the key diagnostic tests for differentiating between stress-induced cardiomyopathy and conventional MI. How common is this condition, and how can we limit the effects of stress-induced cardiomyopathy? Dr. Janet Wright hosts. Produced in Cooperation with

Host: Janet Wright, MD Guest: Scott Sharkey, MD Takotsubo, or stress-induced cardiomyopathy (also known as 'broken heart syndrome'), was first recognized in Japan in the 1990s. Acute emotional or physical stress trigger the condition, which mimics the symptoms of a myocardial infarction (or MI). How can physicians differentiate between stress-induced cardiomyopathy and a more conventional MI, and how is stress-induced cardiomyopathy treated? What characteristics might make a patient more susceptible to developing this condition? Our guest is Dr. Scott Sharkey, senior consulting cardiologist at Minneapolis Heart Institute and director of the Takotsubo cardiomyopathy research program at the Minneapolis Heart Institute Foundation in Minnesota, shares some of the key diagnostic tests for differentiating between stress-induced cardiomyopathy and conventional MI. How common is this condition, and how can we limit the effects of stress-induced cardiomyopathy? Dr. Janet Wright hosts. Produced in Cooperation with

Host: Janet Wright, MD Guest: Scott Sharkey, MD Takotsubo, or stress-induced cardiomyopathy (also known as 'broken heart syndrome'), was first recognized in Japan in the 1990s. Acute emotional or physical stress trigger the condition, which mimics the symptoms of a myocardial infarction (or MI). How can physicians differentiate between stress-induced cardiomyopathy and a more conventional MI, and how is stress-induced cardiomyopathy treated? What characteristics might make a patient more susceptible to developing this condition? Our guest is Dr. Scott Sharkey, senior consulting cardiologist at Minneapolis Heart Institute and director of the Takotsubo cardiomyopathy research program at the Minneapolis Heart Institute Foundation in Minnesota, shares some of the key diagnostic tests for differentiating between stress-induced cardiomyopathy and conventional MI. How common is this condition, and how can we limit the effects of stress-induced cardiomyopathy? Dr. Janet Wright hosts. Produced in Cooperation with

It's all Obsidian this week as Scott Sharkey joins Scooter and Kat to discuss whether the ambitious espionage RPG Alpha Protocol manages to reach 00 Agent status, or if it goes down in flames like the final season of 24. Also check out the Fallout: New Vegas discussion, and a quick preview of what to expect from ATB as we prepare for E3!

It's all Obsidian this week as Scott Sharkey joins Scooter and Kat to discuss whether the ambitious espionage RPG Alpha Protocol manages to reach 00 Agent status, or if it goes down in flames like the final season of 24. Also check out the Fallout: New Vegas discussion, and a quick preview of what to expect from ATB as we prepare for E3!

This week the at1UPpers discuss horseshoes and poker in Red Dead Redemption; our new Shame Night show featuring Frank Cifaldi and Scott Sharkey; Ghostbusters gets the Movie Pitch treatment; and in Final Notes, Jade has two movie recommendations, and what's up with all the Hawkmen?

Jeremy Parish, Scott Sharkey, and Ray Barnholt congregate briefly around a malfunctioning studio setup to talk about the recent spate of worthwhile retro downloads, GDC talks, C-SPAN archives, and more.

Jeremy Parish, Scott Sharkey, and Ray Barnholt congregate briefly around a malfunctioning studio setup to talk about the recent spate of worthwhile retro downloads, GDC talks, C-SPAN archives, and more.

Jeremy Parish, Scott Sharkey, and Ray Barnholt congregate briefly around a malfunctioning studio setup to talk about the recent spate of worthwhile retro downloads, GDC talks, C-SPAN archives, and more.

Jeremy Parish, Scott Sharkey, and Ray Barnholt congregate briefly around a malfunctioning studio setup to talk about the recent spate of worthwhile retro downloads, GDC talks, C-SPAN archives, and more.

Kat Bailey and Scott Sharkey talk about their tour of duty aboard the starship U.S.S. Freak Machine in Star Trek Online, and guest Stiv Tramer plays the role of historian in a lengthy exploration/defense of the roguelike genre.

Kat Bailey and Scott Sharkey talk about their tour of duty aboard the starship U.S.S. Freak Machine in Star Trek Online, and guest Stiv Tramer plays the role of historian in a lengthy exploration/defense of the roguelike genre.

With the Independent Games Festival and GDC coming up we thought it would be a good week to go a little indie. We welcome Braid artist David Hellman, Area 5's Ryan O'donnell, and Scott Sharkey to talk about their experiences in the independent gaming scene. Along the way we sing the praises of Darksiders and lament on the future of the Zelda franchise while shining our collective light on some interesting titles that you can download now for FREE.

With the Independent Games Festival and GDC coming up we thought it would be a good week to go a little indie. We welcome Braid artist David Hellman, Area 5's Ryan O'donnell, and Scott Sharkey to talk about their experiences in the independent gaming scene. Along the way we sing the praises of Darksiders and lament on the future of the Zelda franchise while shining our collective light on some interesting titles that you can download now for FREE.

Continuing our holiday theme, Scott and I reached into our 'epic' spreadsheet of podcast topics to share with your our seasonal leftovers. From dark Disney characters to videogame weapons, these six stories are a little old, but still have a lot of flavor. Join us while we discuss persistent world narcissism, games of the decade, in-game trust, and old-school medallions. As always, you can find all these stories in the show notes. Some discussion starters: - How can lies and mistrust be implemented in a videogame? - How do you feel about collector's editions? How do you flaunt your 'geek' pride? - Epic Mickey: How much do you trust Warren Spector really? - What are the most influential games of the decade? - How do we implement persistent worlds in the most painless way possible?Show notes:- Run time: 30 min 36 sec- "Games of the Decade: An Introduction" by Mitch Krpata, via Insult Swordfighting - "Design of a Decade" by Steve Gaynor, via Fullbright - Epic Mickey details via Game Informer - Modern Warfare 2 Prestige Edition via Joystiq - "Dear persistent worlds: you make me feel bad" by Andrew, via Charge Shot!!! - "Inside the Video Game Weapon Replica Business" by Mike Fahey, via Kotaku - "Fear and Mistrust in Videogames" by Scott Sharkey, via 1Up- Music provided by Brad Sucks

1UP's Scott Sharkey wonders aloud why it's so damn much fun to shoot at unarmed NPCs, and why that might not be all bad.

1UP's Scott Sharkey wonders aloud why it's so damn much fun to shoot at unarmed NPCs, and why that might not be all bad.

1UP's Scott Sharkey expounds on why we play videogames and how much life sucks. Especially for stick figures.

1UP's Scott Sharkey expounds on why we play videogames and how much life sucks. Especially for stick figures.

Four Minute Warning makes its first appearance of the 2009 season and it's been too long. Scott Sharkey joins David, John, and Garnett to field the questions and jump into Whatcha Been Playin that includes Killzone 2, Punch Out, Groov, and more.

Four Minute Warning makes its first appearance of the 2009 season and it's been too long. Scott Sharkey joins David, John, and Garnett to field the questions and jump into Whatcha Been Playin that includes Killzone 2, Punch Out, Groov, and more.

Scott Sharkey re-hijacks at1UP for a second indie games special. This time Braid's David Hellman, Passage and Between's Jason Rohrer, and Love's Eskil Steenberg argue about design philosophy and why they work for themselves.

Scott Sharkey hijacks at1UP this week for a GDC indie games special. He's put together two segments packed with the developers who made several of the most interesting indie games out there. Don't miss this opportunity to get a glimpse into the world of indie gaming.

Episode 1 drops hot and fast like a penny off the Empire State Building and into your skull. Tina Sanchez, Sam Kennedy, Scott Sharkey and Chris Plante team up with special guest, Rebel FM's Anthony Gallegos, to tackle Valve's latest online multiplayer fests, the future of the Good Grief podcast and the frustrating hell child that is Spelunky. Under two hours, Sharkey avoids alcohol poisoning. Huge success!

In which Adam Nelson takes a field trip to San Francisco to visit the CEO of Earth, Scott Sharkey. They are joined by Victor Nuti and his girlfriend Jenna, friends of Adam. From there, the conversation ceases to be about City of Heroes and becomes something even more awesome.

1UP's Scott Sharkey and Jeremy Parish take a closer look at one of Castlevania's darkest moments: the Saturn version of PlayStation classic Symphony of the Night.