Focus on Heart Health

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In this special series, ReachMD examines the reasons behind the dropping rates of death from heart disease: more effective medications, smarter technologies, more efficient treatment guidelines and much more.

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    • May 31, 2022 LATEST EPISODE
    • monthly NEW EPISODES
    • 120 EPISODES


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    Latest episodes from Focus on Heart Health

    Optimizing Dyslipidemic Cardiovascular Residual Risk Reduction with Icosapent Ethyl in Post-MI Patients: Key Takeaways

    Play Episode Listen Later May 31, 2022


    Host: William Boden, MD, FACC, FAHA Patients with ASCVD and a history of MI are at especially high risk for repeat adverse cardiac events. Listen in as Dr. Bill Boden summarizes a post hoc analysis of such patients from the REDUCE-IT trial. Can icosapent ethyl plus a statin provide improved carioprotection by reducing recurrent events in this population? Tune in to learn more! REDUCE-IT is a landmark trial that examined the coadministration of icosapent ethyl and statins in patients for secondary and primary prevention of recurrent events and demonstrated a significant reduction in the key primary and secondary endpoints. This discussion relates to a post hoc analysis of a subset of patients who had prior myocardial infarction, as part of the REDUCE-IT study, and comprised about 45% of the patients with established atherosclerotic coronary disease. The results of this post-MI analysis bring into clear focus that treating hypertriglyceridemia is a critical variable in terms of reducing dyslipidemic risk and overall risk.

    Optimizing Dyslipidemic Cardiovascular Residual Risk Reduction with Icosapent Ethyl in Post-MI Patients: Key Takeaways

    Play Episode Listen Later May 31, 2022


    Host: William Boden, MD, FACC, FAHA Patients with ASCVD and a history of MI are at especially high risk for repeat adverse cardiac events. Listen in as Dr. Bill Boden summarizes a post hoc analysis of such patients from the REDUCE-IT trial. Can icosapent ethyl plus a statin provide improved carioprotection by reducing recurrent events in this population? Tune in to learn more! REDUCE-IT is a landmark trial that examined the coadministration of icosapent ethyl and statins in patients for secondary and primary prevention of recurrent events and demonstrated a significant reduction in the key primary and secondary endpoints. This discussion relates to a post hoc analysis of a subset of patients who had prior myocardial infarction, as part of the REDUCE-IT study, and comprised about 45% of the patients with established atherosclerotic coronary disease. The results of this post-MI analysis bring into clear focus that treating hypertriglyceridemia is a critical variable in terms of reducing dyslipidemic risk and overall risk.

    From Paper to Patient: Applying Guideline Updates to Practice

    Play Episode Listen Later Apr 30, 2022


    Host: Marco Metra, MD Guest: Adrian F. Hernandez, MD, MHS Since the 2017 AHA/ACC/HFSA guidelines, considerable research has been conducted in the care of patients with heart failure, including the impact of iron deficiency. The new 2022 guidelines have considerable updates based on the totality of current evidence. Join Dr. Adrian Hernandez and Dr. Marco Metra as they discuss key highlights from the guidelines and make sure you're staying up to date with the evolving data and best practices.

    The 4 Pillars of Treatment in HFrEF: Does Risk of Hyperkalemia Threaten to Topple Them Over?

    Play Episode Listen Later Apr 30, 2022


    Host: Mikhail Kosiborod, MD Guest: Michael Böhm, MD, FESC The 2022 updates to the ACC/AHA guidelines for heart failure are the first since 2017. In the interim, considerable research has been conducted on the impact of optimal RAASi therapy and the management of hyperkalemia in patients with heart failure. Join Dr. Mikhail Kosiborod and Dr. Michael Böhm as they discuss key highlights from the guidelines and make sure you're staying up to date with the evolving data and best practices.

    From Paper to Patient: Applying Guideline Updates to Practice

    Play Episode Listen Later Apr 30, 2022


    Host: Marco Metra, MD Guest: Adrian F. Hernandez, MD, MHS Since the 2017 AHA/ACC/HFSA guidelines, considerable research has been conducted in the care of patients with heart failure, including the impact of iron deficiency. The new 2022 guidelines have considerable updates based on the totality of current evidence. Join Dr. Adrian Hernandez and Dr. Marco Metra as they discuss key highlights from the guidelines and make sure you're staying up to date with the evolving data and best practices.

    The 4 Pillars of Treatment in HFrEF: Does Risk of Hyperkalemia Threaten to Topple Them Over?

    Play Episode Listen Later Apr 30, 2022


    Host: Mikhail Kosiborod, MD Guest: Michael Böhm, MD, FESC The 2022 updates to the ACC/AHA guidelines for heart failure are the first since 2017. In the interim, considerable research has been conducted on the impact of optimal RAASi therapy and the management of hyperkalemia in patients with heart failure. Join Dr. Mikhail Kosiborod and Dr. Michael Böhm as they discuss key highlights from the guidelines and make sure you're staying up to date with the evolving data and best practices.

    Living with Heart Disease: How a Patient Gave Her Diagnosis Meaning

    Play Episode Listen Later Apr 30, 2018


    Host: Brian P. McDonough, MD, FAAFP Dr. Brian McDonough is joined by Dr. Mark Zucker, Director of the Cardiothoracic Transplantation Program at RWJBH/Newark Beth Israel Medical Center, and his HCM patient and founder of the Hypertrophic Cardiomyopathy Association, Lisa Salberg, to discuss her inspiring story and the importance of early diagnosis.

    Living with Heart Disease: How a Patient Gave Her Diagnosis Meaning

    Play Episode Listen Later Apr 29, 2018


    Host: Brian P. McDonough, MD, FAAFP Dr. Brian McDonough is joined by Dr. Mark Zucker, Director of the Cardiothoracic Transplantation Program at RWJBH/Newark Beth Israel Medical Center, and his HCM patient and founder of the Hypertrophic Cardiomyopathy Association, Lisa Salberg, to discuss her inspiring story and the importance of early diagnosis.

    Time for a Heart-to-Heart: Reflections of Life on the Transplant List

    Play Episode Listen Later Mar 5, 2018


    Host: Maurice Pickard, MD Guest: Bob Mitchell Quite suddenly, Bob Mitchell became very sick. He would endure three near-fatal episodes of ventricular tachycardia due to a heart muscle comprised of 54% scar tissue, as well as heart surgeries, two harrowing months of waiting on the transplant list for a new heart on life-supporting IV drips (during which time a malignant tumor was detected in his kidney), partial nephrectomy surgery to remove the cancer, another month of waiting, a 12-hour heart and kidney transplant surgery, and 100 days on life support in four different hospitals. Host Dr. Maurice Pickard talks with novelist Bob Mitchell, author of Time for a Heart-to-Heart: Reflections on Life in the Face of Death about his inspiring story of the triumph of hope in the face of the direst of circumstances.

    Time for a Heart-to-Heart: Reflections of Life on the Transplant List

    Play Episode Listen Later Mar 4, 2018


    Host: Maurice Pickard, MD Guest: Bob Mitchell Quite suddenly, Bob Mitchell became very sick. He would endure three near-fatal episodes of ventricular tachycardia due to a heart muscle comprised of 54% scar tissue, as well as heart surgeries, two harrowing months of waiting on the transplant list for a new heart on life-supporting IV drips (during which time a malignant tumor was detected in his kidney), partial nephrectomy surgery to remove the cancer, another month of waiting, a 12-hour heart and kidney transplant surgery, and 100 days on life support in four different hospitals. Host Dr. Maurice Pickard talks with novelist Bob Mitchell, author of Time for a Heart-to-Heart: Reflections on Life in the Face of Death about his inspiring story of the triumph of hope in the face of the direst of circumstances.

    Heart of the Matter: Emerging Treatment Options for Congenital Heart Disease

    Play Episode Listen Later Feb 9, 2018


    Host: John J. Russell, MD Guest: Thomas Doyle, MD About 40,000 babies are born with Congenital Heart Disease each year, making it one of the most common birth defects and causes of infant death in the US. CHD is usually present at birth but shows very few outward signs and, in most cases has no known cause or origin. New and evolving surgical techniques, along with the dawn of pediatric heart transplant, are transforming the field of pediatric cardiology and offer new options for CHD patients. Host Dr. John Russell talks with Dr. Thomas Doyle about how continued research, improved surgical treatments and, emerging technology have altered the course of treatment for CHD, resulting in approximately 69% of children with CHD now living to age 18. Dr. Thomas Doyle is the Ann and Monroe Carell Jr. Family Associate Professor of Pediatrics at Vanderbilt University. Dr. Doyle was a 2016 Project Heart CHD research grant recipient.

    Heart of the Matter: Emerging Treatment Options for Congenital Heart Disease

    Play Episode Listen Later Feb 8, 2018


    Host: John J. Russell, MD Guest: Thomas Doyle, MD About 40,000 babies are born with Congenital Heart Disease each year, making it one of the most common birth defects and causes of infant death in the US. CHD is usually present at birth but shows very few outward signs and, in most cases has no known cause or origin. New and evolving surgical techniques, along with the dawn of pediatric heart transplant, are transforming the field of pediatric cardiology and offer new options for CHD patients. Host Dr. John Russell talks with Dr. Thomas Doyle about how continued research, improved surgical treatments and, emerging technology have altered the course of treatment for CHD, resulting in approximately 69% of children with CHD now living to age 18. Dr. Thomas Doyle is the Ann and Monroe Carell Jr. Family Associate Professor of Pediatrics at Vanderbilt University. Dr. Doyle was a 2016 Project Heart CHD research grant recipient.

    What to Know About the Latest Recommended Guidelines for High Blood Pressure in Adults

    Play Episode Listen Later Jan 29, 2018


    Host: Jennifer Caudle, DO Guest: Robert Carey, MD, FAHA Under the 2017 Hypertension Guidelines, 46 percent of U.S. adults have high blood pressure which is up from 32 percent under the old benchmark. This interview covers the key information physicians need to know from the new guidelines in order to improve blood pressure control rates. Host Dr. Jennifer Caudle talks with Dr. Robert Carey, vice chair of the 2017 hypertension guidelines about the new recommendations and their impact on clinical practice. The American Medical Association's M.A.P. framework and blood pressure improvement program is dedicated to helping health care providers improve blood pressure control in their adult patient populations, and a new AMA resource can help you succeed in Medicare's Merit-Based Incentive Payment System (MIPS) while you manage and treat high blood pressure. This resource outlines the different measures that relate to hypertension management in each MIPS performance category, potential MIPS score results, and related AMA resources that can help you improve the health of your patients with hypertension while checking all your MIPS boxes along the way. Please click here to access the New AMA resource pairs BP quality improvement with MIPS The …

    How the Latest Hypertension Guidelines Will Change Your Practice

    Play Episode Listen Later Jan 29, 2018


    Host: Jennifer Caudle, DO Guest: Paul Whelton, MB, MD, MSc, FAHA Under the 2017 Hypertension Guidelines, 46 percent of U.S. adults have high blood pressure, which is up from 32 percent under the old benchmark. This interview covers the key information physicians need to know from the new guidelines in order to improve blood pressure control rates. Host Dr. Jennifer Caudle chats with Dr. Paul Whelton, chair of the 2017 blood pressure guidelines writing committee, about how the new guidelines will affect patients. The American Medical Association's M.A.P. framework and blood pressure improvement program is dedicated to helping health care providers improve blood pressure control in their adult patient populations, and a new AMA resource can help you succeed in Medicare's Merit-Based Incentive Payment System (MIPS) while you manage and treat high blood pressure. This resource outlines the different measures that relate to hypertension management in each MIPS performance category, potential MIPS score results, and related AMA resources that can help you improve the health of your patients with hypertension while checking all your MIPS boxes along the way. Please click here to access the New AMA resource pairs BP quality improvement with MIPS The views, information, or …

    How Hypertension Guidelines Changes Are Impacting Our Patients

    Play Episode Listen Later Jan 29, 2018


    Host: Jennifer Caudle, DO Guest: Karol Watson, MD, PhD Under the 2017 Hypertension Guidelines, 46 percent of U.S. adults have high blood pressure which is up from 32 percent under the old benchmark. This interview covers the key information physicians need to know from the new guidelines in order to improve blood pressure control rates. Host Dr. Jennifer Caudle is joined by Dr. Karol Watson, an attending cardiologist and a Professor of Medicine/Cardiology at the David Geffen School of Medicine at UCLA. Dr. Watson is a principal investigator for several large National Institutes of Health research studies, including the Diabetes Prevention Program Outcomes Study and the Multi-Ethnic Study of Atherosclerosis. She reacts to the new guidelines and reflects on what these changes could mean to patients. The American Medical Association's M.A.P. framework and blood pressure improvement program is dedicated to helping health care providers improve blood pressure control in their adult patient populations, and a new AMA resource can help you succeed in Medicare's Merit-Based Incentive Payment System (MIPS) while you manage and treat high blood pressure. This resource outlines the different measures that relate to hypertension management in each MIPS performance category, potential MIPS score results, and related AMA resources that can help you improve the health of …

    What to Know About the Latest Recommended Guidelines for High Blood Pressure in Adults

    Play Episode Listen Later Jan 28, 2018


    Host: Jennifer Caudle, DO Guest: Robert Carey, MD, FAHA Under the 2017 Hypertension Guidelines, 46 percent of U.S. adults have high blood pressure which is up from 32 percent under the old benchmark. This interview covers the key information physicians need to know from the new guidelines in order to improve blood pressure control rates. Host Dr. Jennifer Caudle talks with Dr. Robert Carey, vice chair of the 2017 hypertension guidelines about the new recommendations and their impact on clinical practice. The American Medical Association's M.A.P. framework and blood pressure improvement program is dedicated to helping health care providers improve blood pressure control in their adult patient populations, and a new AMA resource can help you succeed in Medicare’s Merit-Based Incentive Payment System (MIPS) while you manage and treat high blood pressure. This resource outlines the different measures that relate to hypertension management in each MIPS performance category, potential MIPS score results, and related AMA resources that can help you improve the health of your patients with hypertension while checking all your MIPS boxes along the way. Please click here to access the New AMA resource pairs BP quality improvement with MIPS The ...

    How the Latest Hypertension Guidelines Will Change Your Practice

    Play Episode Listen Later Jan 28, 2018


    Host: Jennifer Caudle, DO Guest: Paul Whelton, MB, MD, MSc, FAHA Under the 2017 Hypertension Guidelines, 46 percent of U.S. adults have high blood pressure, which is up from 32 percent under the old benchmark. This interview covers the key information physicians need to know from the new guidelines in order to improve blood pressure control rates. Host Dr. Jennifer Caudle chats with Dr. Paul Whelton, chair of the 2017 blood pressure guidelines writing committee, about how the new guidelines will affect patients. The American Medical Association's M.A.P. framework and blood pressure improvement program is dedicated to helping health care providers improve blood pressure control in their adult patient populations, and a new AMA resource can help you succeed in Medicare’s Merit-Based Incentive Payment System (MIPS) while you manage and treat high blood pressure. This resource outlines the different measures that relate to hypertension management in each MIPS performance category, potential MIPS score results, and related AMA resources that can help you improve the health of your patients with hypertension while checking all your MIPS boxes along the way. Please click here to access the New AMA resource pairs BP quality improvement with MIPS The views, information, or ...

    How Hypertension Guidelines Changes Are Impacting Our Patients

    Play Episode Listen Later Jan 28, 2018


    Host: Jennifer Caudle, DO Guest: Karol Watson, MD, PhD Under the 2017 Hypertension Guidelines, 46 percent of U.S. adults have high blood pressure which is up from 32 percent under the old benchmark. This interview covers the key information physicians need to know from the new guidelines in order to improve blood pressure control rates. Host Dr. Jennifer Caudle is joined by Dr. Karol Watson, an attending cardiologist and a Professor of Medicine/Cardiology at the David Geffen School of Medicine at UCLA. Dr. Watson is a principal investigator for several large National Institutes of Health research studies, including the Diabetes Prevention Program Outcomes Study and the Multi-Ethnic Study of Atherosclerosis. She reacts to the new guidelines and reflects on what these changes could mean to patients. The American Medical Association's M.A.P. framework and blood pressure improvement program is dedicated to helping health care providers improve blood pressure control in their adult patient populations, and a new AMA resource can help you succeed in Medicare’s Merit-Based Incentive Payment System (MIPS) while you manage and treat high blood pressure. This resource outlines the different measures that relate to hypertension management in each MIPS performance category, potential MIPS score results, and related AMA resources that can help you improve the health of ...

    Toward Instantaneous Care: Real-Time Monitoring of Vital Signs

    Play Episode Listen Later Jul 7, 2017


    Host: Matt Birnholz, MD Guest: Denise Devine What if there was a way to monitor vital signs in real time? Denise Devine, Co-Founder of RTM Vital Signs, LLC, is working on just that. She is joined by Dr. Matt Birnholz at the Villanova Health Summit to discuss this innovative technology in development, which opens up the possibility of collecting continuous health data from patients to enhance point-of-care treatments.

    Toward Instantaneous Care: Real-Time Monitoring of Vital Signs

    Play Episode Listen Later Jul 6, 2017


    Host: Matt Birnholz, MD Guest: Denise Devine What if there was a way to monitor vital signs in real time? Denise Devine, Co-Founder of RTM Vital Signs, LLC, is working on just that. She is joined by Dr. Matt Birnholz at the Villanova Health Summit to discuss this innovative technology in development, which opens up the possibility of collecting continuous health data from patients to enhance point-of-care treatments.

    Unclog the Arteries: Treatment Options for Arterial Disease

    Play Episode Listen Later Jun 7, 2017


    Host: Barnett Mennen, MD Guest: Grace Wang, MD, FACS Unclogging patient arteries is a key step to preventing stroke in patients with arterial disease. Whether it be preventing the operative stage, or surgery itself, advances in treatment at Penn Medicine are seeking to lessen the effects of arterial disease. Host Dr. Barry Mennen welcomes Dr. Grace Wang, vascular surgeon and Director of the Vascular Laboratory at the Hospital of the University of Pennsylvania. Dr. Wang highlights the importance of early detection in arterial disease, as well as the symptoms and risk factors of the disease. She will also discuss the current and upcoming surgical intervention options at Penn Medicine.

    Unclog the Arteries: Treatment Options for Arterial Disease

    Play Episode Listen Later Jun 6, 2017


    Host: Barnett Mennen, MD Guest: Grace Wang, MD, FACS Unclogging patient arteries is a key step to preventing stroke in patients with arterial disease. Whether it be preventing the operative stage, or surgery itself, advances in treatment at Penn Medicine are seeking to lessen the effects of arterial disease. Host Dr. Barry Mennen welcomes Dr. Grace Wang, vascular surgeon and Director of the Vascular Laboratory at the Hospital of the University of Pennsylvania. Dr. Wang highlights the importance of early detection in arterial disease, as well as the symptoms and risk factors of the disease. She will also discuss the current and upcoming surgical intervention options at Penn Medicine.

    Treating Erectile Dysfunction: Key Cardiovascular Considerations

    Play Episode Listen Later Oct 10, 2016


    Host: Alan S. Brown, MD, FACC, FAHA, FNLA Live from the Clinical Lipid Update of the National Lipid Association in Amelia Island, FL, host Dr. Alan Brown welcomes Dr. Robert Kloner, Vice President of Translation at Huntington Medical Research Institutes and Professor of Medicine in the Cardiovascular Division of Keck School of Medicine at the University of Southern California. Dr. Kloner discusses the cardiovascular risk factors associated with erectile dysfunction, safety and efficacy of erectile disfunction drugs, and benefits vs risks of supplementing with testosterone.

    Treating Erectile Dysfunction: Key Cardiovascular Considerations

    Play Episode Listen Later Oct 9, 2016


    Host: Alan S. Brown, MD, FNLA Live from the Clinical Lipid Update of the National Lipid Association in Amelia Island, FL, host Dr. Alan Brown welcomes Dr. Robert Kloner, Vice President of Translation at Huntington Medical Research Institutes and Professor of Medicine in the Cardiovascular Division of Keck School of Medicine at the University of Southern California. Dr. Kloner discusses the cardiovascular risk factors associated with erectile dysfunction, safety and efficacy of erectile disfunction drugs, and benefits vs risks of supplementing with testosterone.

    Pharmacometabolomics to Predict Statin Response: Ready for Prime Time?

    Play Episode Listen Later Oct 3, 2016


    Host: Alan S. Brown, MD, FACC, FAHA, FNLA Live from the Clinical Lipid Update of the National Lipid Association in Amelia Island, FL, host Dr. Alan Brown welcomes Dr. Rhoda Cooper-DeHoff. Dr. Cooper-DeHoff is an Associate Professor in the Department of Pharmacotherapy and Translational Research and Division of Cardiovascular Medicine of the Colleges of Pharmacy and Medicine at the University of Florida. She is also Associate Director of the Center for Pharmacogenomics at this institution. Dr. Cooper-DeHoff discusses the rise of pharmacometabolomics, genomic testing, and pharmacogenetic testing in lipidology, with particular emphasis on predictive mapping for statin responses.

    Pharmacometabolomics to Predict Statin Response: Ready for Prime Time?

    Play Episode Listen Later Oct 2, 2016


    Host: Alan S. Brown, MD, FNLA Live from the Clinical Lipid Update of the National Lipid Association in Amelia Island, FL, host Dr. Alan Brown welcomes Dr. Rhoda Cooper-DeHoff. Dr. Cooper-DeHoff is an Associate Professor in the Department of Pharmacotherapy and Translational Research and Division of Cardiovascular Medicine of the Colleges of Pharmacy and Medicine at the University of Florida. She is also Associate Director of the Center for Pharmacogenomics at this institution. Dr. Cooper-DeHoff discusses the rise of pharmacometabolomics, genomic testing, and pharmacogenetic testing in lipidology, with particular emphasis on predictive mapping for statin responses.

    Triglyceride-Lowering Therapies: Addressing Gaps in the Guidelines

    Play Episode Listen Later Sep 26, 2016


    Host: Alan S. Brown, MD, FACC, FAHA, FNLA Live from the Clinical Lipid Update of the National Lipid Association in Amelia Island, FL, host Dr. Alan Brown welcomes Dave Dixon, PharmD, Clinical Pharmacist and Associate Professor of Pharmacology at Virginia Commonwealth University School of Pharmacy. Dr. Dixon is also a Board Certified Pharmacotherapy Specialist, Clinical Lipid Specialist, and Fellow of the National Lipid Association. He serves as a Regional Representative for the Southeast Chapter of NLA and on the Journal of Clinical Lipidology Editorial Board. Dr. Dixon discusses guidelines for treating hypertriglyceridemia, effective therapies for reducing triglyceride levels, and emerging lipid-lowering therapies in development.

    Triglyceride-Lowering Therapies: Addressing Gaps in the Guidelines

    Play Episode Listen Later Sep 25, 2016


    Host: Alan S. Brown, MD, FNLA Live from the Clinical Lipid Update of the National Lipid Association in Amelia Island, FL, host Dr. Alan Brown welcomes Dave Dixon, PharmD, Clinical Pharmacist and Associate Professor of Pharmacology at Virginia Commonwealth University School of Pharmacy. Dr. Dixon is also a Board Certified Pharmacotherapy Specialist, Clinical Lipid Specialist, and Fellow of the National Lipid Association. He serves as a Regional Representative for the Southeast Chapter of NLA and on the Journal of Clinical Lipidology Editorial Board. Dr. Dixon discusses guidelines for treating hypertriglyceridemia, effective therapies for reducing triglyceride levels, and emerging lipid-lowering therapies in development.

    PCSK9 Antibodies for Dyslipidemia: Efficacy, Safety, and Non-Lipid Effects

    Play Episode Listen Later Sep 19, 2016


    Host: Alan S. Brown, MD, FACC, FAHA, FNLA Live from the Clinical Lipid Update of the National Lipid Association in Amelia Island, FL, host Dr. Alan Brown welcomes Dr. Eugenia Gianos. Dr. Gianos is an assistant professor in the Department of Medicine and co-clinical director of the Center for the Prevention of Cardiovascular Disease at the NYU School of Medicine. Dr. Gianos discusses the effectiveness, potential side effects, and patient outcomes with PCSK9 antibodies for management of dyslipidemia.

    PCSK9 Antibodies for Dyslipidemia: Efficacy, Safety, and Non-Lipid Effects

    Play Episode Listen Later Sep 18, 2016


    Host: Alan S. Brown, MD, FNLA Live from the Clinical Lipid Update of the National Lipid Association in Amelia Island, FL, host Dr. Alan Brown welcomes Dr. Eugenia Gianos. Dr. Gianos is an assistant professor in the Department of Medicine and co-clinical director of the Center for the Prevention of Cardiovascular Disease at the NYU School of Medicine. Dr. Gianos discusses the effectiveness, potential side effects, and patient outcomes with PCSK9 antibodies for management of dyslipidemia.

    New Medication for High Cholesterol Not Cost-Effective

    Play Episode Listen Later Aug 16, 2016


    [Read the Article] The FDA recently approved a new class of cholesterol-lowering drugs called PCSK9 inhibitors. These new medications could substantially reduce heart attacks, strokes and cardiovascular deaths, however they are very expensive. A new study evaluated the cost-effectiveness of this therapy and how increased use might affect the U.S. healthcare system. Researchers from the University of California San Francisco used a simulation model that included all U.S. adults 35 and older and evaluated outcomes such as expected numbers of deaths due to cardiovascular disease, heart attacks and strokes, and balanced this with the cost and potential benefits of these drugs. With an estimated 9 million people eligible for this therapy and a price of $14,000 per patient per year, researchers estimated that total prescription drugs expenditures could increase by 40 percent. In order to be cost-effective, the PCSK9 inhibitor costs would have to come down to about $4,000 a year. [Watch more videos of The JAMA Report]

    New Medication for High Cholesterol Not Cost-Effective

    Play Episode Listen Later Aug 15, 2016


    [Read the Article] The FDA recently approved a new class of cholesterol-lowering drugs called PCSK9 inhibitors. These new medications could substantially reduce heart attacks, strokes and cardiovascular deaths, however they are very expensive. A new study evaluated the cost-effectiveness of this therapy and how increased use might affect the U.S. healthcare system. Researchers from the University of California San Francisco used a simulation model that included all U.S. adults 35 and older and evaluated outcomes such as expected numbers of deaths due to cardiovascular disease, heart attacks and strokes, and balanced this with the cost and potential benefits of these drugs. With an estimated 9 million people eligible for this therapy and a price of $14,000 per patient per year, researchers estimated that total prescription drugs expenditures could increase by 40 percent. In order to be cost-effective, the PCSK9 inhibitor costs would have to come down to about $4,000 a year. [Watch more videos of The JAMA Report]

    Device Reduces Risk of Brain Injury After Heart Valve Replacement

    Play Episode Listen Later Aug 9, 2016


    [Read the Article] Patients who might benefit from a heart valve replacement but are too ill for open heart surgery can sometimes undergo a less invasive procedure known as transcatheter aortic valve implantation or "TAVI". About 10% of patients undergoing TAVI can experience small strokes and related brain injury as a complication. A new study found that the use of a cerebral protection device, which captures debris dislodged from blood vessels during the TAVI procedure, reduced the number and volume of brain lesions seen on MRI. Researchers from the University of Leipzig Heart Center, Germany studied 100 patients with an average age of 80 who underwent TAVI. Half of the patients received the cerebral protection device and the other half did not. Patients underwent brain MRIs before the implantation and again at 2 and at 7 days after the procedure. The results found that using the filter device helped to decrease the number of brain lesions seen in the brain by about half. [Watch more videos of The JAMA Report]

    Device Reduces Risk of Brain Injury After Heart Valve Replacement

    Play Episode Listen Later Aug 8, 2016


    [Read the Article] Patients who might benefit from a heart valve replacement but are too ill for open heart surgery can sometimes undergo a less invasive procedure known as transcatheter aortic valve implantation or "TAVI". About 10% of patients undergoing TAVI can experience small strokes and related brain injury as a complication. A new study found that the use of a cerebral protection device, which captures debris dislodged from blood vessels during the TAVI procedure, reduced the number and volume of brain lesions seen on MRI. Researchers from the University of Leipzig Heart Center, Germany studied 100 patients with an average age of 80 who underwent TAVI. Half of the patients received the cerebral protection device and the other half did not. Patients underwent brain MRIs before the implantation and again at 2 and at 7 days after the procedure. The results found that using the filter device helped to decrease the number of brain lesions seen in the brain by about half. [Watch more videos of The JAMA Report]

    PVC Ablation Procedures for Ventricular Tachycardia

    Play Episode Listen Later Jun 13, 2016


    Host: Jennifer Caudle, DO Guest: Francis Marchlinski, MD Host Dr. Jennifer Caudle welcomes Dr. Francis E. Marchlinski, Richard T. and Angela Clark President's Distinguished Professor and Director of the Electrophysiology Laboratory at the University of Pennsylvania. Dr. Marchlinski will review the epidemiology of PVCs, the kinds of problems that PVCs can cause, and how these problems manifest as symptoms in patients. He will also review the effectiveness of catheter ablation as a current treatment option for ventricular tachycardia (VT), a potenially serious complication of PVC's.

    PVC Ablation Procedures for Ventricular Tachycardia

    Play Episode Listen Later Jun 12, 2016


    Host: Jennifer Caudle, DO Guest: Francis Marchlinski, MD Host Dr. Jennifer Caudle welcomes Dr. Francis E. Marchlinski, Richard T. and Angela Clark President's Distinguished Professor and Director of the Electrophysiology Laboratory at the University of Pennsylvania. Dr. Marchlinski will review the epidemiology of PVCs, the kinds of problems that PVCs can cause, and how these problems manifest as symptoms in patients. He will also review the effectiveness of catheter ablation as a current treatment option for ventricular tachycardia (VT), a potenially serious complication of PVC's.

    Cardiovascular Risk Reduction in the Elderly: Best Lipid Strategies

    Play Episode Listen Later May 9, 2016


    Host: Alan S. Brown, MD, FACC, FAHA, FNLA Guest: Joyce Ross, MSN, CRNP, CS, CLS, FNLA, FPCNA Host Dr. Alan Brown welcomes Joyce Ross, MSN, CRNP, FNLA, President-Elect of the National Lipid Association. Joyce serves as a consultative education specialist in cardiovascular risk intervention with the University of Pennsylvania Health System. Their discussion focuses on lipid management to reduce atherosclerotic cardiovascular disease (ASCVD) risk in elderly patient populations. Thhis interview was recorded live at the National Lipid Association in San Diego, California for the 2016 Spring Clinical Lipid Update.

    Cardiovascular Risk Reduction in the Elderly: Best Lipid Strategies

    Play Episode Listen Later May 8, 2016


    Host: Alan S. Brown, MD, FNLA Guest: Joyce Ross, MSN, CRNP, CS, CLS, FNLA, FPCNA Host Dr. Alan Brown welcomes Joyce Ross, MSN, CRNP, FNLA, President-Elect of the National Lipid Association. Joyce serves as a consultative education specialist in cardiovascular risk intervention with the University of Pennsylvania Health System. Their discussion focuses on lipid management to reduce atherosclerotic cardiovascular disease (ASCVD) risk in elderly patient populations. Thhis interview was recorded live at the National Lipid Association in San Diego, California for the 2016 Spring Clinical Lipid Update.

    Bridging The Cardiology Gap: Care Priorities for Adults With Congenital Heart Disease

    Play Episode Listen Later Apr 25, 2016


    Host: Jennifer Caudle, DO Guest: Yuli Kim, MD Advancements in cardiac surgery and medical care for pediatric patients over the past decades have produced a sizeable population of adults living with congenital heart disease. These adults and their unique health care needs expose an emerging gap in expertise for the cardiology community, where training in congenital heart disease management has traditionally been the provence of pediatric subspecialists. How can these adult patients find cardiologists familiar with their particular anatomy and problems, and what special care strategies must cardiologists be familiar with to provide optimal care? Dr. Jennifer Caudle will discuss the selective health care needs and personalized management strategies for adults with congenital heart disease with Dr. Yuli Kim, Medical Director of the Philadelphia Adult Congenital Heart Disease Center and Assistant Professor of Medicine & Pediatrics at the University of Pennsylvania and the Children's Hospital of Philadelphia.

    Bridging The Cardiology Gap: Care Priorities for Adults With Congenital Heart Disease

    Play Episode Listen Later Apr 24, 2016


    Host: Jennifer Caudle, DO Guest: Yuli Kim, MD Advancements in cardiac surgery and medical care for pediatric patients over the past decades have produced a sizeable population of adults living with congenital heart disease. These adults and their unique health care needs expose an emerging gap in expertise for the cardiology community, where training in congenital heart disease management has traditionally been the provence of pediatric subspecialists. How can these adult patients find cardiologists familiar with their particular anatomy and problems, and what special care strategies must cardiologists be familiar with to provide optimal care? Dr. Jennifer Caudle will discuss the selective health care needs and personalized management strategies for adults with congenital heart disease with Dr. Yuli Kim, Medical Director of the Philadelphia Adult Congenital Heart Disease Center and Assistant Professor of Medicine & Pediatrics at the University of Pennsylvania and the Children's Hospital of Philadelphia.

    Combination of Diet and Exercise Offers Benefits in Patients with a Common Type of Heart Failure

    Play Episode Listen Later Jan 26, 2016


    [Read the Article] Among obese older patients with an increasingly common type of heart failure, calorie restriction and/or exercise training improved their ability to participate in physical activity without experiencing shortness of breath, according to a new study.Heart failure with preserved ejection fraction (HFPEF) is the most rapidly increasing form of heart failure in the United States. Although the heart pumps normally, it does not fill with enough blood because the lower chamber of the heart is too stiff. More than eighty percent of patients with HFPEF are overweight or obese. Despite multiple studies, so far, no currently available medications have improved symptoms in patients with HFPEF.Researchers from the Wake Forest School of Medicine randomly assigned 100 older obese participants with HFPEF to 20 weeks of diet, exercise, or both. They found that the exercise participants lost three percent of body weight, the diet group lost seven percent and the combined group lost ten percent of body weight. Patients in both the diet and exercise groups showed improvement in their ability to participate in exercise without significant symptoms. [Watch more videos of The JAMA Report]

    Combination of Diet and Exercise Offers Benefits in Patients with a Common Type of Heart Failure

    Play Episode Listen Later Jan 25, 2016


    [Read the Article] Among obese older patients with an increasingly common type of heart failure, calorie restriction and/or exercise training improved their ability to participate in physical activity without experiencing shortness of breath, according to a new study.Heart failure with preserved ejection fraction (HFPEF) is the most rapidly increasing form of heart failure in the United States. Although the heart pumps normally, it does not fill with enough blood because the lower chamber of the heart is too stiff. More than eighty percent of patients with HFPEF are overweight or obese. Despite multiple studies, so far, no currently available medications have improved symptoms in patients with HFPEF.Researchers from the Wake Forest School of Medicine randomly assigned 100 older obese participants with HFPEF to 20 weeks of diet, exercise, or both. They found that the exercise participants lost three percent of body weight, the diet group lost seven percent and the combined group lost ten percent of body weight. Patients in both the diet and exercise groups showed improvement in their ability to participate in exercise without significant symptoms. [Watch more videos of The JAMA Report]

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