Podcasts about Propionibacterium

Dr. Ju Hee Katzman, Infectious Diseases attending and Program Director of the USF ID Fellowship Program, reviews anaerobic infections in this new presentation. In a question and answer format, Dr. Katzman covers the medically significant anaerobic bacteria and categorizes them by their clinical morphology. Next, she covers several clinical scenarios where the treatment of anaerobic infections is indicated, and those in which it is less advisable. Lastly, Dr. Katzman covers specific anaerobic infections, including the Clostridia, the anaerobic gram positive cocci, Bacterioides, Propionibacterium, and Actinomyces.

Join Nurse Doza as he delves into the complex world of acne, a condition affecting millions worldwide. This episode will enlighten listeners about the various factors that contribute to acne, including hormonal fluctuations, dietary influences, lifestyle habits, and more. Nurse Doza brings his wealth of experience in treating patients with acne and emphasizes the significance of addressing acne's root causes for truly effective, long-lasting solutions.   Timestamps: 00:00 - Introduction 01:14 - Defining Acne: An Overview 05:20 - Root Cause 1: Inflammation and Acne 10:16 - Root Cause 2: Bacterial Overgrowth and Acne 15:24 - Root Cause 3: Hormonal Imbalance and Acne 21:13 - Root Cause 4: Dietary Influence and Acne 25:42 - Root Cause 5: Impact of Certain Medications on Acne 30:57 - Wrap-up and Final Thoughts Unleash Your Skin's Potential with MSW Nutrition's Liver Love Take control of your acne with MSW Nutrition's Liver Love, a formulation designed to support optimal liver health and hormone balance. By addressing the root causes of acne, Liver Love can help you achieve healthier, clearer skin. Shop MSW Liver Love Here and start your journey to healthier skin today.   SHOW NOTES: Delve deeper into the intricacies of acne with the below topics discussed during the episode: 1. Understanding Acne: The Basics - A look at what acne is and how it forms. 2. Inflammation: A Key Culprit in Acne - How inflammation can contribute to acne and potential solutions. 3. Bacterial Overgrowth: An Unseen Enemy** - Examining the impact of bacterial overgrowth on acne and potential remedies. 4. **Hormonal Imbalance: A Silent Trigger** - The link between hormonal imbalances and acne, and how to counteract it. 5. **Food Sensitivity: An Unexplored Factor** - Discussing how certain foods can potentially trigger acne. 6. **Medications: A Double-Edged Sword** - Analyzing how certain medications can lead to acne breakouts. 7. **Liver Health: The Unsung Hero** - The critical role liver health plays in maintaining hormonal balance and healthy skin, and how Liver Love can provide the needed support. REFERENCES: Understanding Acne: The Basics - National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). Inflammation: A Key Culprit in Acne - Recent advances in understanding Propionibacterium acnes (Cutibacterium acnes) in acne, NCBI. Bacterial Overgrowth: An Unseen Enemy - How is folliculitis related to acne?, LearnSkin, Folliculitis: Symptoms and Causes, Mayo Clinic, and Recent advances in understanding Propionibacterium acnes (Cutibacterium acnes) in acne, NCBI. Hormonal Imbalance: A Silent Trigger - The Role of Estrogen in Acne, Acne.org, Conversion of estrone to estradiol and estradiol to estrone in postmenopausal women, PubMed, and Influence of Age and Obesity on Serum Estradiol, Estrone, and Sex Hormone Binding Globulin Concentrations following Oral Estrogen Administration in Postmenopausal Women, NCBI. Food Sensitivity: An Unexplored Factor - Milk consumption and acne in teenaged boys, NCBI, Acne and Gut Health, Weston A Price Foundation, and Milk consumption and acne in adolescent girls, PubMed. Medications: A Double-Edged Sword - What medications can cause acne?, Acne.org.  

That awkward moment when… *crickets*. Grab a charcuterie board of pumpkins and green peppers as we discuss our hot takes with Betsy and Annie.

Esta edição do Pílula Farmacêutica faz um alerta para a banalização do tratamento antiacne. Como o problema atinge, principalmente, a pele do rosto, as pessoas acreditam poder utilizar inadvertidamente a droga isotretinoína, princípio ativo de remédios para o tratamento de casos graves de acne. Porém, avisa a acadêmica Giovanna Bingre, orientada pela professora Regina Andrade, da Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP) da USP, o surgimento de espinhas no rosto deve ser investigado por um dermatologista, que orientará o melhor tratamento, incluindo os efeitos colaterais da isotretinoína, se for o caso, ou de outras terapias.  Adianta a acadêmica que é bom lembrar que a acne é o adoecimento do folículo pilossebáceo. Pilo, de pelo, e sebáceo, relativo à produção das glândulas sebáceas. E que quando este folículo adoece, acontece uma produção exagerada de sebo e queratina, facilitando a infecção pela bactéria Propionibacterium acnes, que consome as secreções e levam à inflamação, responsável pelas espinhas.  A doença pode ter várias causas, entre elas, os fatores hormonais, mais comuns na adolescência. Em sua forma mais grave, não responde aos antibióticos. O que é a isotretinoína?  Informa Giovanna que se trata de um composto relacionado à vitamina A (ácido retinóico), que “age na acne como regulador da diferenciação celular, inibindo a proliferação celular nos sebócitos”. Assim, ao reduzir “a produção de sebo, a acne tende a melhorar”. O remédio, em apresentação de cápsula, deve ser administrado de acordo com o peso do paciente por um período médio de tratamento de sete meses.  Para que serve a isotretinoína? Giovanna alerta para o absurdo de algumas pessoas com poucas espinhas desejarem o tratamento com a isotretinoína. Somente os casos graves da doença podem utilizar o medicamento. Segundo a acadêmica, a droga deve ser “uma das últimas opções de tratamento da acne e deve ser sempre usada com o acompanhamento e recomendação de um médico”. Quais são os efeitos colaterais da isotretinoína? São vários os efeitos colaterais desse remédio, adianta Giovanna, que elenca os principais: anemia; irritação e ressecamento dos olhos (o que pode facilitar uma conjuntivite); ressecamento da pele e dos lábios; dores musculares e nas articulações; aumento do colesterol; queda de cabelo e depressão. Também podem ocorrer, mais raramente, catarata, aumento da pressão intracraniana, doença de Crohn e hepatite.  Além de todos esses malefícios, a isotretinoína é altamente teratogênica (pode causar malformações em fetos e aumentar as chances de hidrocefalia nos bebês), sendo totalmente contraindicada para gestantes e lactantes. Com tantos efeitos adversos, a isotretinoína só pode ser comprada com receita “acompanhada de notificação de receita especial e só é possível retirar medicação para 30 dias de tratamento de cada vez”, diz Giovanna.

This episode: Giant bacteria with many chromosomes in each cell carry extra genes to help them live in many different environments! Download Episode (8.7 MB, 12.7 minutes) Show notes: Microbe of the episode: Propionibacterium virus SKKY News item   Takeaways We think of bacteria a certain way: too small to see and having mostly just a single large chromosome with all the genes they need for their lifestyle and not much more. And most bacteria are like that. But not all! Giant bacteria exist, some of which can be so large that individual cells can be seen without a microscope.   Achromatium species are one such kind of bacteria. They form clumps of minerals that take up most of their internal volume, but their cells are big enough to see and handle. In order to supply all parts of their vast innards with proteins, they have many copies of their chromosome distributed throughout their cytoplasm.   In this study, a survey of Achromatium genomes from all different kinds of ecosystem revealed that even different species in very different environments all seem to share one set of genetic functions, but only use the ones they need for their particular lifestyle while archiving the rest.   Journal Paper: Ionescu D, Zoccarato L, Zaduryan A, Schorn S, Bizic M, Pinnow S, Cypionka H, Grossart H-P. Heterozygous, Polyploid, Giant Bacterium, Achromatium, Possesses an Identical Functional Inventory Worldwide across Drastically Different Ecosystems. Mol Biol Evol https://doi.org/10.1093/molbev/msaa273. Other interesting stories: As with other infections, gut microbiota correlates with severity of COVID-19 Fungi help plants defend against aphids   Email questions or comments to bacteriofiles at gmail dot com. Thanks for listening! Subscribe: Apple Podcasts, Google Podcasts, Android, or RSS. Support the show at Patreon, or check out the show at Twitter or Facebook.

A pele oleosa, além de possibilitar o surgimento de doenças como a acne, também provoca desconforto, como a sensação do rosto estar sujo, maquiagens como bases e corretivos não durarem o dia todo, incompatibilidade com produtos como protetores solares e hidratantes. Nesta edição do Pílula Farmacêutica, a acadêmica Giovanna Bingre, orientanda da professora Regina Andrade, da Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP) da USP, fala sobre os problemas causados pela pele oleosa e como mantê-la sob controle.  Primeiro é preciso conhecer um pouco sobre a pele, que possui diversas partes diferentes, cada uma com suas peculiaridades. Para  perceber isso, é só comparar a textura e composição da pele das palmas das mãos com a pele ao redor dos seus olhos, por exemplo, que refletem as funções de determinada parte da pele, podendo variar a espessura, a enervação e também a quantidade de glândulas, como a sebácea.   Giovanna explica que glândulas sebáceas secretam sebo, que é uma espécie de óleo, que possui muitas funções, como proteger fisicamente a pele, emulsificar substâncias, proteger contra radiação solar, bactérias e fungos. “Porém, o excesso desse sebo confere uma característica muito comum entre a população brasileira: a pele oleosa, um grande problema para todos que sofrem com ela.”  Uma pele oleosa pode levar à acne, doença cutânea caracterizada pela hiperplasia das glândulas sebáceas, hiperqueratinização do folículo da pele, inflamação e infecção do folículo pela bactéria Propionibacterium acnes. “Essa doença, apesar de não deixar o indivíduo debilitado, tem grandes impactos na vida de quem sofre com ela, deixando cicatrizes, problemas de autoestima, que refletem em distúrbios psiquiátricos como ansiedade e depressão, e questões sociais, como dificuldades em interagir com outras pessoas, que podem contribuir com o desemprego.”  Lavar o rosto excessivamente, na tentativa de manter o rosto seco, pode levar a uma situação chamada rebote, quando se retira demais o sebo da pele do rosto e o corpo entende que está desprotegido, produzindo ainda mais óleo. “Uma pessoa que não tem a pele oleosa pode acabar tendo problemas com a produção de sebo por causa da limpeza excessiva ou pelo uso de produtos muito fortes para o seu tipo de pele. Logo, uma pessoa que tenha a pele normal, mista e até mesmo seca pode vir a ter pele oleosa por causa disso.”  Para manter a pele sob controle, o mais indicado é procurar um dermatologista, que vai identificar o tipo de pele do paciente e indicar produtos de limpeza e hidratação adequados ou prescrever outros tratamentos e, em último caso, remédios para o controle da acne. “Os medicamentos para o tratamento de acne possuem efeitos adversos sérios, só devendo ser usados como última opção.”  Ouça este episódio do Pílula Farmacêutica na íntegra no player acima. Pílula Farmacêutica   Apresentação: Kimberly Fuzel e Giovanna Bingre

El acné vulgar es una afección cutánea que se relaciona con la producción de sebo por las glándulas sebáceas, la inflamación de los comedones (puntos negros y espinillas) y la hiperproliferación de Propionibacterium acnes (bacteria).El proceso es sencillo: El poro de la piel se conecta con las glándulas sebáceas (producción de sebo) a través del folículo. El sebo transporta a través del folículo las células de piel muerta. A veces, el sebo, el vello y las células crean un tapón en el poro. Las bacterias presentes provocan hinchazón en este y cuando empieza a deshacerse el tapón aparece el grano o espinilla.Hay varios que afectan en su aparición, y uno de ellos es la alimentación. Aunque no existe la dieta antiacné sí que podemos realizar cambios en la alimentación para prevenir su aparición y/o reducir su severidad. Los alimentos que podrían influir de forma negativa son: - Azúcar.- Ultraprocesados.- Lácteos, especialmente los desanatados.- Carne. Los alimentos que podrían influir de forma positiva son: - Verduras.- Frutas.- Frutos secos y semillas.- Té.- Legumbres.- Cereales integrales.- AOVE.- Pescado azul.

A dermatologist is a medical doctor, earning an MD (Doctor of Medicine) or a DO (Doctor of Osteopathic Medicine) license that allows the individual to specialize in treating many of the physical featuresthat make you human. Acne is the most common skin disease in the world — 80 percent of all people experience an acne breakout at some point in their lives, often during the teenage years. Acne is a skin condition in which the pores become clogged with sebum (oil) and dead skin cells. These clogs are referred to as comedones or blackheads and whiteheads. Propionibacterium acnes bacteria found on the skin can becomes trapped in these clogged pores. As the bacteria thrive on the sebum and pustule begins to form. Over time this triggers an inflammatoryresponse from and a deep tender cystic lesion may form, which may eventually lead to follicle rupture if untreated. Eczema, also called atopic dermatitis, is one of the diagnoses you get when you have red spots on your skin that become inflamed and itchy. A top dermatologist in Manhattan recognizes the symptoms right away and recommends the best treatment for eczema based on your current health and medical history. A chronic yet routine skin condition in people over the age of 30, rosacea generally manifests itself as the extreme visibility of red blood vessels in your cheeks, nose, and forehead. It often appears in flare-ups lasting for several weeks or even months, only to then temporarily disappear into remission. Unless you have it treated, it will continue to recur. Psoriasis is one of the more misunderstood skin disorders today. It’s a condition where your skin cells’ life cycle changes so that they regenerate much more rapidly. In fact, skin cells multiply 10 times faster with psoriasis. As a result, the cells build up on the surface of your skin.

Ajánlott irodalom: Verstraete, S., Verbruggen, S. C., Hordijk, J. A., Vanhorebeek, I., Dulfer, K., Güiza, F., … Jacobs, A. (2019). Long-term developmental effects of withholding parenteral nutrition for 1 week in the paediatric intensive care unit : a 2-year follow-up of the PEPaNIC international , randomised , controlled trial, 7(February), 141–153. https://doi.org/10.1016/S2213-2600(18)30334-5 Marik, P. E. (2014). Enteral nutrition in the critically ill: Myths and misconceptions. Critical Care Medicine, 42(4), 962–969. https://doi.org/10.1097/CCM.0000000000000051 Martinez, E. E., Ariagno, K., Arriola, A., Lara, K., & Mehta, N. M. (2015). Challenges to nutrition therapy in the pediatric critically ill obese patient. Nutrition in Clinical Practice, 30(3), 432–439. https://doi.org/10.1177/0884533615569887 Fitz-gibbon, S., Tomida, S., Chiu, B., Nguyen, L., Du, C., Miller, J. F., … Weinstock, G. M. (2014). The Management of Acute Pancreatitis in the Pediatric Population: A Clinical Report from the NASPGHAN Pancreas Committee Maisam, 133(9), 2152–2160. https://doi.org/10.1038/jid.2013.21.Propionibacterium

On this 2nd episode of the JAAOS Unplugged podcast series, host Andy Jensen, MD, summarizes research articles from the February 15, 2019 issue of JAAOS, including: Opioid Prescribing Practices of Orthopaedic Surgeons: Results of a National Survey, Incidence of Posteromedial Meniscocapsular Separation and the Biomechanical Implications on the Anterior Cruciate Ligament, Patient Outcomes After Revision of Anatomic Total Shoulder Arthroplasty to Reverse Shoulder Arthroplasty for Rotator Cuff Failure or Component Loosening: A Matched Cohort Study, and Hemolysis Is a Diagnostic Adjuvant for Propionibacterium acnes Orthopaedic Shoulder Infections.     Following the article summaries, Dr. Jensen interviews Michael George, MD to discuss his review article Latissimus Dorsi Tendon Rupture.   Follow this link to download these and other articles from the February 15th, 2019 issue of JAAOS: https://journals.lww.com/jaaos/toc/2019/02150   The JAAOS Unplugged podcast series is brought to you by the Journal of the American Academy of Orthopaedic Surgeons and the AAOS Resident Assembly.

This episode: How social bacteria societies function: by sharing enzyme packages with each other that can contain toxins that are deadly for rivals but not for friends! Thanks to Chris Vasallo for his contribution! Download Episode (12.4 MB, 13.6 minutes) Show notes: Microbe of the episode: Propionibacterium virus PAD20 News item Journal Paper: Vassallo CN, Cao P, Conklin A, Finkelstein H, Hayes CS, Wall D. 2017. Infectious polymorphic toxins delivered by outer membrane exchange discriminate kin in myxobacteria. eLife 6:e29397. Other interesting stories: Attaching proteins to little bioplastic beads to make useful nanoparticles (paper) Fungi are very important for nutrient cycling in the world Friendly soil microbes inject plant pathogens with toxin Microbes are carried around the world through the atmosphere Arctic algae can grow even in super cold and dark conditions   Email questions or comments to bacteriofiles at gmail dot com. Thanks for listening! Subscribe: iTunes, RSS, Google Play. Support the show at Patreon, or check out the show at Twitter or Facebook

This podcast covers the JBJS issue for July 2015. Featured are articles covering Association Between Orthopaedic Outpatient Satisfaction and Non-Modifiable Patient Factors; The Effect of Smoking on Short-Term Complications Following Total Hip and Knee Arthroplasty; recorded commentary by Dr. Mont; In-Home Telerehabilitation Compared with Face-to-Face Rehabilitation After Total Knee Arthroplasty; recorded commentary by Dr. Spangehl; Early Versus Late Culture Growth of Propionibacterium acnes in Revision Shoulder Arthroplasty.

This podcast covers the JBJS issue for July 2015. Featured are articles covering Association Between Orthopaedic Outpatient Satisfaction and Non-Modifiable Patient Factors; The Effect of Smoking on Short-Term Complications Following Total Hip and Knee Arthroplasty; recorded commentary by Dr. Mont; In-Home Telerehabilitation Compared with Face-to-Face Rehabilitation After Total Knee Arthroplasty; recorded commentary by Dr. Spangehl; Early Versus Late Culture Growth of Propionibacterium acnes in Revision Shoulder Arthroplasty.

Andrea Campisano Fondazione Edmund Mach, Trento, ITALY speaks on "Interkingdom transfer of the human pathogen Propionibacterium acnes to the plant endosphere, and its adaptation". This seminar has been recorded by ICGEB Trieste

The production of porphyrins by Propionibacterium acnes (P. acnes) as a contributing pathogenic factor in the aetiology of acne is the object of this investigation. High–performance liquid chromatographic (HPLC) analysis was used to investigate in vivo samples of porphyrins produced by P. acnes from comedones prior to treatment of a set of 55 patients with a variety of systemic forms of treatment. For all patients mainly coproporphyrin III was identified, but also coproporphyrin I and protoporphyrin at considerably lower concentrations. Polar porphyrins could not be detected. Wide variations of porphyrin concentrations between individual patients were found. Collective evaluation showed that only systemic isotretinoin monotherapy for more than three months led to a reduction of porphyrins. Other systemic forms of therapy, such as minocycline, a combination of oral isotretinoin with local treatment or various combinations of local therapy (benzoyl peroxide, benzoyl peroxide and retinoids, benzoyl peroxide and azelaic acid) had no persistent effect on porphyrin production. When the porphyrin production of individual patients was analysed repeatedly over time, clinical improvement was associated with lowered concentrations of porphyrins with local forms of therapy. An unchanged or worsening skin condition was associated with increased porphyrin production. The reduction of coproporphyrin III production by P. acnes where there is improvement as a result of therapy supports the pathogenetic significance of P. acnes and of the porphyrin fractions it produces for the emergence of acne.

Background The inflammation in acne vulgaris is widely thought to be induced by an immunological reaction to Propionibacterium acnes. Objectives In the present study we examined the local host response mechanism of keratinocytes 3 and 6 h after stimulation with viable and heat- killed P. acnes. Methods The quantitative expression of cytokines was measured at the mRNA level by real time RT-PCR. Results The co-incubation of keratinocytes with active, but not heat- killed, P. acnes modulated an adequate cytokine response for IL-1beta, GM-CSF, and IL-8. High-performance liquid chromatography analysis of the in vivo porphyrin pattern secreted by P. acnes revealed a predominance of coproporphyrin III in inflammatory acne lesions. This same porphyrin fraction also modestly induced IL-8 expression by keratinocytes. Conclusions This cytokine pattern may favor a chemotactic response and implicates P. acnes and coproporphyrin III in the recruitment of leukocytes to the site of infection and in the development of inflammatory lesions.