POPULARITY
3 episodes with acute pancreatitis
4 episodes with acute pancreatitis
3 episodes with acute pancreatitis
2 episodes with acute pancreatitis
2 episodes with acute pancreatitis
2 episodes with acute pancreatitis
2 episodes with acute pancreatitis
2 episodes with acute pancreatitis
2 episodes with acute pancreatitis
This full-length episode on the inpatient management of acute pancreatitis includes not only the admission framework, but also key clinical pearls on the background, pathophysiology, etiologies, presentation, diagnosis, treatment, and complications associated with the disease to help take your understanding to the next level! Visit pointofcaremedicine.com to see the templates, pearls, literature, and other resources discussed in this episode. Our mission is to create accessible and easy-to-use digital resources that help healthcare professionals tackle common clinical presentations at the point of care, without getting bogged down by unnecessary details or trivia. Timestamps 00:00:00 - Background and Epidemiology 00:01:13 - A Note on Chronic Pancreatitis 00:01:31 - Admission Checklist 00:03:49 - HPI Intake 00:04:33 - Physical Exam 00:05:20 - Etiology and Differential 00:06:20 - Plan - Work Up 00:07:30 - Plan - Treatment 00:09:31 - If You Remember Nothing Else 00:10:04 - Pearls - Pathophysiology 00:11:15 - Pearls - Etiology and Risk Factors 00:12:56 - Pearls - Presentation and Diagnosis 00:15:56 - Pearls - Treatment 00:18:08 - Pearls – Complications Show Notes Reviews Acute Pancreatitis: A Review (JAMA, 2021) Acute Pancreatitis (NEJM, 2016) Trials WATERFALL Trial - Aggressive (20 ml/kg bolus + 3 ml/kg/hr) vs Non-Aggressive (10 ml/kg bolus + 1.5 ml/kg/hr) fluid resuscitation in acute pancreatitis - fluid overload resulted in 20.5% vs 6.3% of patients but no difference in the development of moderately severe or severe pancreatitis (NEJM, 2022) Other Literature Enteral versus parenteral nutrition for acute pancreatitis (Cochrane, 2010) A Critical Evaluation of Laboratory Tests in Acute Pancreatitis (Am J Gastroenterol, 2002) Blogs and Summaries Clinical Problem Solvers - Acute Pancreatitis Illness Script Internet Book of Critical Care - Pancreatitis Radiopaedia - Imaging Findings in Acute Pancreatitis Pathway Guidelines Summary - Acute Pancreatitis
This Quick-Admit episode on acute pancreatitis will focus on only the highest-yield information you need when admitting a patient to the hospital. To take your understanding of the disease to the next level, check out the full-length episode for more information including a discussion of the most important clinical pearls and literature. Visit pointofcaremedicine.com to see the templates, pearls, literature, and other resources discussed in this episode. Our mission is to create accessible and easy-to-use digital resources that help healthcare professionals tackle common clinical presentations at the point of care, without getting bogged down by unnecessary details or trivia.
Live Nursing Review with Regina MSN, RN! Every Monday & Wednesday we are live. LIKE, FOLLOW, & SUB @ReMarNurse for more. 7 Day of NCLEX: https://ReMarNurse.com/7days Quick Facts for NCLEX Next Gen Study Guide here - https://bit.ly/QF-NGN Study with Professor Regina MSN, RN every Monday as you prepare for NCLEX Next Gen. ► Create Free V2 Account - http://www.ReMarNurse.com ► Get Quick Facts Next Gen - https://bit.ly/QF-NGN ► Subscribe Now - http://bit.ly/ReMar-Subscription ► GET THE PODCAST: https://remarnurse.podbean.com/ ► WATCH LESSONS: http://bit.ly/ReMarNCLEXLectures/ ► FOLLOW ReMar on Instagram: https://www.instagram.com/ReMarNurse/ ► LIKE ReMar on Facebook: https://www.facebook.com/ReMarReview/ ReMar Review features weekly NCLEX review questions and lectures from Regina M. Callion MSN, RN. ReMar is the #1 content-based NCLEX review and has helped thousands of repeat testers pass NCLEX with a 99.2% student success rate! ReMar focuses on 100% core nursing content and as a result, has the best review to help nursing students to pass boards - fast!
In this episode we walk you through our approach to pancreatitis, including potential etiologies (not just the favourite scorpion bite!), and discuss recent evidence on management. Written by: Dr. Ikram Abow-Mohamed & Dr. Amine Zoughlami (Internal Medicine Residents)Reviewed by: Dr. Constantine Soulelis (Gastroenterologist) & Dr. Sanabelle Zaabat (General Internist)Support the show
In this podcast Dr. Harry Cridge, an ACVIM and ECVIM board-certified specialist in small animal internal medicine, will discuss his approach to the management of pancreatitis in dogs. This podcast will include discussion of Panoquell®-CA1, a novel and innovative solution for neutrophilic inflammation in acute pancreatitis. Dr. Cridge is an ACVIM and ECVIM board-certified internal medicine specialist with clinical and research interests in disorders of the exocrine pancreas. He is 1 of 3 RCVS recognized specialist in Small Animal Medicine (Gastroenterology) worldwide. Dr. Cridge obtained his veterinary medical degree from University College Dublin, before moving to the United States to pursue an internship and small animal internal medicine residency at Mississippi State University. Following residency, he joined the faculty at Michigan State University where he is an Associate Professor. He has published in multiple prestigious journals and textbooks. PANOQUELL®-CA1 (fuzapladib sodium for injection) PANOQUELL® is a registered trademark of Ishihara Sangyo Kaisha, Ltd. © 2023 Ceva Animal Health, LLC PANOQUELL®-CA1 is conditionally approved by FDA pending a full demonstration of effectiveness under application number 141 to 567. It is a violation of federal law to use this product other than as directed in the labeling. CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian. *IMPORTANT SAFETY INFORMATION: The safe use of PANOQUELL®-CA1 has not been evaluated in dogs with cardiac disease, hepatic failure, or renal impairment; dogs that are pregnant, lactating, or intended for breeding; or puppies under 6 months of age. PANOQUELL®-CA1 should not be used in dogs with a known hypersensitivity to fuzapladib sodium. PANOQUELL®-CA1 is a highly protein-bound drug and its use with other highly protein-bound medications has not been studied. The most common adverse effects in the pilot field study were anorexia, digestive tract disorders, respiratory tract disorders, and jaundice. PANOQUELL®-CA1 is not for use in humans. Limited data is available on the potential teratogenic effects of fuzapladib sodium. Therefore, anyone who is pregnant, breastfeeding, or planning to become pregnant should avoid direct contact with PANOQUELL®-CA1. For additional information on the use of PANOQUELL®-CA1, please refer to the package insert. See prescribing and product information: https://www.panoquell.com/
Ajay Singhvi, MD, The Oregon Clinic-Gastroenterology East at Gateway CME Credit Available for all Providence Providers In order to claim CME credit, please click on the following link: https://forms.office.com/r/gej1X6C3vz (or copy & paste into your browser) Accreditation Statement:Providence Oregon Region designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1 creditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Providence Oregon Region is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Planning Committee & Faculty Disclosure:The planning committee and faculty have indicated no relevant financial relationships with an ACCME-defined ineligible company. Their planning contributions were evidence-based and unbiased. All financial relationships (if any) have been mitigated. Original Date: September 19, 2023End Date: September 19, 2024
Ajay Singhvi, MD, The Oregon Clinic-Gastroenterology East at Gateway CME Credit Available for all Providence Providers In order to claim CME credit, please click on the following link: https://forms.office.com/r/gej1X6C3vz (or copy & paste into your browser) Accreditation Statement:Providence Oregon Region designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1 creditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Providence Oregon Region is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Planning Committee & Faculty Disclosure:The planning committee and faculty have indicated no relevant financial relationships with an ACCME-defined ineligible company. Their planning contributions were evidence-based and unbiased. All financial relationships (if any) have been mitigated. Original Date: September 19, 2023End Date: September 19, 2024
Thank you for listening to this episode of "Health and Fitness" from the Nezpod Studios! Enjoy your night or the start of your day, spiced by our top-notch health and fitness/wellness updates coined from the best sources around the globe: made only for your utmost enjoyment and enlightenment… Click on subscribe to get more spicy episodes for free! See you again soon on the next episode of Health and fitness updates! Learn more about your ad choices. Visit megaphone.fm/adchoices
Episode 17! In this episode we talk about "Aggressive of Moderate Fluid Resuscitation in Acute Pancreatitis" published September 2022 by de-Madaria et al in the New England Journal of Medicine and then talk about the landmark study "Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock" by Rivers et al also NEJM but November 2001WATERFALL: https://pubmed.ncbi.nlm.nih.gov/36103415/EGDT: https://pubmed.ncbi.nlm.nih.gov/11794169/Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
Thank you for listening to this episode of "Health and Fitness" from the Nezpod Studios! Enjoy your night or the start of your day, spiced by our top-notch health and fitness/wellness updates coined from the best sources around the globe: made only for your utmost enjoyment and enlightenment… Click on subscribe to get more spicy episodes for free! See you again soon on the next episode of Health and fitness updates! Learn more about your ad choices. Visit megaphone.fm/adchoices
In this episode, we review the high-yield topic of Acute Pancreatitis from the Gastrointestinal section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets --- Send in a voice message: https://podcasters.spotify.com/pod/show/medbulletsstep1/message
Host: Peter Buch, MD, FACG, AGAF, FACP Guest: Daniel Strand, MD Acute pancreatitis can be tricky to diagnose and treat. To help us understand how to better manage this condition, Dr. Peter Buch is joined by Dr. Daniel Strand, the Director of Pancreatobiliary Endoscopy at UVA Health in Charlottesville and an Associate Professor of GI Hepatology to share management updates for patients with recurrent acute and chronic pancreatitis.
Join us as we review recent practice-changing articles addressing the questions: Do weekend warriors experience a mortality benefit from exercise? Is an aggressive fluid strategy superior to a moderate strategy in acute pancreatitis? Does an invite for colonoscopy decrease colon cancer-related mortality? Did the benefits of intensive blood pressure control continue after the SPRINT trial ended? Fill your plate with a stack of hot tofurkey cakes! Featuring Drs. Era Kryzhanovskaya (@erakryzhmd), Nora Taranto (@norataranto), Paul Williams (@PaulNWilliamz), Rahul Ganatra (@rbganatra), and Matt Watto (@doctorwatto). Claim free CME for this episode at curbsiders.vcuhealth.org! Episodes | Subscribe | Spotify | Swag! | Mailing List | askcurbsiders@gmail.com | Free CME! Show Segments Intro, disclaimer Do weekend warriors experience a mortality benefit? Should you choose aggressive or moderate fluid resuscitation for acute pancreatitis? Does an invite for screening colonoscopy reduce colon cancer and CRC-related mortality? Did benefits from the SPRINT trial persist in observational follow up? Outro Credits Written and Hosted by: Era Kryzhanovskaya, MD, Nora Taranto MD; Rahul Ganatra MD, MPH; Paul Williams, MD, FACP, Matthew Watto MD, FACP Cover Art: Matthew Watto MD, FACP Reviewer: Rahul Ganatral MD, MPH Technical Production: Pod Paste Sponsor: Better Help Visit betterhelp.com/curb to save 10% off your first month. Sponsor: Birch Living Go to birchliving.com/curb to get $400 off and 2 free eco-rest pillows.
In this episode, we discuss a recently published randomised controlled trial evaluating the role of aggressive fluid resuscitation strategy in mild acute pancreatitis.
Join us this week as we discuss the diagnosis and management of a familiar presentation - acute pancreatitis. Brian, Adnan, Awais and Mo cover everything from diagnosis to management and even debate some new literature on the topic. As always, included are some good laughs.
Contributor: Aaron Lessen, MD Educational Pearls: Historically, pancreatitis has been treated with aggressive IV fluid rehydration. Recently published data shows this may not be appropriate. A randomized, controlled, multi-hospital trial evaluated outcomes for patients with acute pancreatitis receiving lactated Ringer's solution Aggressive fluid resuscitation group received 20ml/kg bolus + 3ml/hour Moderate fluid resuscitation groups received either 10 ml/kg bolus if hypovolemic or no bolus if normovolemic. Both moderate resuscitation groups received 1.5ml/hr. The primary outcome was development of moderately severe or severe pancreatitis. 22.1% of aggressive fluid resuscitation and 17.3% of moderate fluid resuscitation patients developed primary outcome. The safety outcome was fluid overload. Fluid overload developed in 20.5% of aggressive resuscitation group and only 6.3% of moderate resuscitation group. This trial was ended early due to differences in safety outcomes without obvious difference in primary outcome Overall, aggressive fluid resuscitation had no benefit in treatment of acute pancreatitis and providers should be aware of fluid overload risk. References de-Madaria E, Buxbaum JL, Maisonneuve P, et al. Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis. N Engl J Med. 2022;387(11):989-1000. doi:10.1056/NEJMoa2202884 Summarized by Kirsten Hughes, MS4 | Edited by John Spartz, MD & Erik Verzemnieks, MD In an effort to promote diversity, equity, and inclusion in Emergency Medicine, The Emergency Medical Minute is proud to present our 2nd annual Diversity and Inclusion Award. We support increasing the representation of underrepresented groups in medicine and extend this award to individuals applying to emergency medicine residencies during the 2022-2023 cycle. For information on award eligibility and the application process, visit https://emergencymedicalminute.com/edi-award/
Show Notes: Coming Soon TrueLearn Link: https://truelearn.referralrock.com/l/EDDYJOEMD25/ Discount code: EDDYJOEMD25 Citation: de-Madaria E, Buxbaum JL, Maisonneuve P, García García de Paredes A, Zapater P, Guilabert L, Vaillo-Rocamora A, Rodríguez-Gandía MÁ, Donate-Ortega J, Lozada-Hernández EE, Collazo Moreno AJR, Lira-Aguilar A, Llovet LP, Mehta R, Tandel R, Navarro P, Sánchez-Pardo AM, Sánchez-Marin C, Cobreros M, Fernández-Cabrera I, Casals-Seoane F, Casas Deza D, Lauret-Braña E, Martí-Marqués E, Camacho-Montaño LM, Ubieto V, Ganuza M, Bolado F; ERICA Consortium. Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis. N Engl J Med. 2022 Sep 15;387(11):989-1000. doi: 10.1056/NEJMoa2202884. PMID: 36103415. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/eddyjoemd/support
In this episode, host Alyssa Watson, DVM, is joined by Daniel Langlois DVM, DACVIM (SAIM), and Harry Cridge MVB, MS, DACVIM (SAIM), MRCVS, to talk about her recent Clinician's Brief article, “Acute Pancreatitis in Dogs.” Dr. Cridge and Dr. Langlois comprehensively review this condition from both referral and general practice perspectives. They navigate the confusing topic of diagnosing pancreatitis and emphasize the most important aspects of treatment, including that steroids may actually be an option in a few cases.Resources:https://www.cliniciansbrief.com/article/acute-pancreatitis-dogsContact us:Podcast@briefmedia.comWhere to find us:Cliniciansbrief.com/podcastsFacebook.com/clinciansbriefTwitter: @cliniciansbriefInstagram: @clinicians.briefThe Team:Alyssa Watson, DVM - HostAlexis Ussery - Producer & Digital Content CoordinatorRandall Stupka - Podcast Production & Sound Editing
This week, Rob and Zach will be teaching you everything you need to know about Acute Pancreatitis.We will be discussing the following topics within this episode on Acute Pancreatitis!Definition of Acute PancreatitisCauses / PathophysiologyClinical FeaturesPhysical Exam FindingsDiagnosisTreatmentTo follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.orgFollow us on:YouTube: https://www.youtube.com/ninjanerdscienceInstagram: https://www.instagram.com/ninjanerdlecturesFacebook: https://www.facebook.com/NinjaNerdLecturesTwitter: https://twitter.com/ninjanerdsciDiscord: https://discord.com/invite/3srTG4dngWTikTok: https://www.tiktok.com/@ninjanerdlecturesSupport the show
This BMJ Best Practice podcast is on acute pancreatitis. Acute pancreatitis is a common and serious condition. The incidence in the UK is about 50 per 100,000 per year. And it can cause a range of complications including acute renal failure, pancreatic abscess, and chronic pancreatitis. In this podcast, Kieran Walsh interviews Professor Scott Tenner on acute pancreatitis. Scott is Clinical Professor of Medicine at State University of New York and author of the BMJ Best Practice topic on this condition. BMJ Relevant topic link - https://bestpractice.bmj.com/topics/en-gb/3000118 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner's judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.
Learn what you really need to diagnose pancreatitis, when to use imaging sources and what is most important in management! Rapidly treating Acute Pancreatitis might change its course! We're joined by Dr. Kaveh Sharzehi @sharzehi of Oregon Health & Science University (@OHSUNews). Claim free CME for this episode at curbsiders.vcuhealth.org! Episodes | Spotify | Swag! | Top Picks | Mailing List | thecurbsiders@gmail.com | Free CME! Show Segments Intro, disclaimer, guest bio Guest one-liner Case from Kashlak Risk factors for severe course Use of Scoring Systems Requirements to make the diagnosis Rational use of imaging Initial management: fluids, analgesia, and nutrition When to use antibiotics When to perform cholecystectomy Most common complications and interventions How to follow up in the outpatient setting Credits Producer & Scriptwriters: Monee Amin MD and Meredith Trubitt MD Show Notes & Infographics: Andréa Perdigão Cover Art: Monee Amin MD Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP Reviewer: Molly Heublein MD Executive Producer: Beth Garbitelli Showrunner: Matthew Watto MD, FACP Editor: Clair Morgan of nodderly.com Guest: Kaveh Sharzehi MD, MS Sponsor: BetterHelp Visit betterhelp.com/curb for 10% of your first month. Sponsor: MedMastery Visit www.medmastery.com/curbsiders for a 15% lifetime discount! CME Partner: VCU Health CE The Curbsiders are partnering with VCU Health Continuing Education to offer FREE continuing education credits for physicians and other healthcare professionals. Visit curbsiders.vcuhealth.org and search for this episode to claim credit.
What started as pancreatitis, turned into massive transfusion protocol and a visit to interventional radiology. In this episode, Sarah, Katleen, and Marissa discuss a case that took an unexpected turn for the worse. They break down the pathophysiology of pancreatitis, it's treatment, and the nurse's role in the patient's recovery.
Gastro: 7. Harry and Dan talk through the causes, investigations and management of acute pancreatitis - alongside how to present such information in a clinical exam setting. This episode was vetted by Miss Alexandra Cope, Consultant General & Colorectal surgeon at Wexham Park Hospital, Berkshire.
Amylase testing has long been used as a diagnostic tool for pancreatitis, despite amylase levels not being a definitive indicator of pancreatitis. Lipase offers a more useful diagnostic result, as its readings are a better indicator of inflammation of the pancreas, according to James Nichols, PhD, a member of the CAP Quality Practices Committee. Ordering a combination of amylase and lipase is a common practice, but the combination does not increase the sensitivity over a single test. Likewise, serial testing of lipase does not offer better monitoring or treatment. As part of the CAP Test Ordering Program, a new module (https://capatholo.gy/3Du78fr) provides information and resources for the pathologist to address unnecessary testing volumes in the laboratory while still providing effective patient care, as Dr. Nichols explains in this CAPcast.
In this episode of Critical Matters, we discuss the management of severe acute pancreatitis. Our guest is Dr. Marc G Besselink (@MarcBesselink). He is Professor of pancreatic and hepatobiliary(HPB) surgery, at Amsterdam University Medical Centers in the Netherlands. Dr. Besselink is a member of the Dutch Pancreatitis Study Group and is the senior investigator of the POINTER clinical trial (recently published in the New England Journal of Medicine). Additional Resources: Acute Pancreatitis: https://bit.ly/3D6kONK POINTER Clinical Trial - Immediate Versus Postponed Intervention for Infected Necrotizing Pancreatitis: https://bit.ly/3wxRLQN PYTHON Clinical Trial - Early Versus On-demand Nasoenteric Tube Feeding in Acute Pancreatitis: https://bit.ly/3km1STK APEC Clinical Trial - Urgent Versus Conservative ERCP for Acute Pancreatitis: https://bit.ly/3qlVK1I Books Mentioned in this Episode: The House of God by Samuel Shem: https://amzn.to/3wy8Lq2
Acute Pancreatitis with Dr. Kothari by Dr. Laura Caputo
Take Home Points Pancreatitis is diagnosed by a combination of clinical features (epigastric pain with radiation to back, nausea/vomiting etc) and diagnostic tests (lipase 3x normal, CT scan) A RUQ US should be performed looking for gallstones as this finding significantly alters management The focus of management is on supportive care. IV fluids, while central ... Read more The post REBEL Core Cast 64.0 – Acute Pancreatitis appeared first on REBEL EM - Emergency Medicine Blog.
This episode covers acute pancreatitis.- risk factors- aetiology- pathophysiology (a beloved question in the exam)- workup- severity classification (including the apache score, modified glasgow critiera, ranson's criteria, IAP/APA guidelines, and revised Atlanta classification)- radiological classification (revised Atlanta) and radiological severity classification systems- management of pancreatitis--- including acute management which addresses fluid resuscitation, nutrition, ERCP, as well as when to do the lap chole.--- and management of complications including how to do a cystgastrostomy, how to manage pancreatic necrosis, and more!Pancreatitis is a favourite question in the exam so this is a high yield episode! DisclaimerThe information in this podcast is intended as a revision aid for the purposes of the General Surgery Fellowship Exam.This information is not to be considered to include any recommendations or medical advice by the author or publisher or any other person. The listener should conduct and rely upon their own independent analysis of the information in this podcast.The author provides no guarantees or assurances in relation to any connection between the content of this podcast and the general surgical fellowship exam. No responsibility or liability is accepted by the author in relation to the performance of any person in the exam. This podcast is not a substitute for candidates undertaking their own preparations for the exam.To the maximum extent permitted by law, no responsibility or liability is accepted by the author or publisher or any other person as to the adequacy, accuracy, correctness, completeness or reasonableness of this information, including any statements or information provided by third parties and reproduced or referred to in this document. To the maximum extent permitted by law, no responsibility for any errors in or omissions from this document, whether arising out of negligence or otherwise, is accepted.The information contained in this podcast has not been independently verified.© Amanda Nikolic 2021
In this episode, we review the high-yield topic of Acute Pancreatitis from the Gastrointestinal section.
In this episode of Bowel Sounds, hosts Drs. Temara Hajjat and Jason Silverman talk to Dr. Aliye Uc, head of the division of pediatric gastroenterology at the University of Iowa, about her pearls for the evaluation and management of acute and acute recurrent pancreatitis. She also discusses her journey to becoming an expert in pancreatic diseases in childhood and her inspiration for creating INSPPIRE, a network of medical centers committed to learning more about pediatric pancreatitis.As always, the discussion, views, and recommendations in this podcast are the sole responsibility of the hosts and guests and are subject to change over time with advances in the field.Produced by: Temara HajjatSpecial requests:Thank you to everyone for listening to our podcast. If you enjoyed this content and thought it was useful, we ask you to consider doing any or all of the following three things:Tell one person who you think would like this type of content about the podcast. We want to reach more GI doctors and trainees and general pediatricians, pediatric residents, and medical students.Leave a review on Apple Podcasts -- this helps more people discover our podcast.You can also support the show by making a donation to the NASPGHAN FoundationSupport the show (https://www.naspghan.org/content/87/en/foundation/donate)
Dr. Sudarshan Hebbar, Chief Medical Officer, CalciMedica talks about developing drugs that are focused on targeting CRAC channels, calcium release activated calcium channels, in order to modulate these channels to help treat diseases that have a significant inflammatory component. Initially developed drugs for acute pancreatitis targeting both the pancreas and the lung. Now conducting large trial in patients with severe and critical COVID-19 as many of the mechanisms that are shared in the development of lung disease with COVID-19 are shared with acute pancreatitis. Strong evidence that their drug Auxora might be effective for a variety of disorders that cause lung injury. @CalciMedicaInc #COVID19 #CriticalCare #inflammatorydiseases #pancreatitis #CRACChannelinhibitors CalciMedica.com Download the transcript here
Dr. Sudarshan Hebbar, Chief Medical Officer, CalciMedica talks about developing drugs that are focused on targeting CRAC channels, calcium release activated calcium channels, in order to modulate these channels to help treat diseases that have a significant inflammatory component. Initially developed drugs for acute pancreatitis targeting both the pancreas and the lung. Now conducting large trial in patients with severe and critical COVID-19 as many of the mechanisms that are shared in the development of lung disease with COVID-19 are shared with acute pancreatitis. Strong evidence that their drug Auxora might be effective for a variety of disorders that cause lung injury. @CalciMedicaInc #COVID19 #CriticalCare #inflammatorydiseases #pancreatitis #CRACChannelinhibitors CalciMedica.com Listen to the podcast here.
This episode covers acute pancreatitis!
Howard Reber, MD, emeritus professor of surgery at UCLA, discusses how to treat acute pancreatitis. Related Article(s): Acute Pancreatitis
Howard Reber, MD, emeritus professor of surgery at UCLA, discusses how to diagnose acute pancreatitis. Related Article(s): Acute Pancreatitis
Quick review for your PANCE,PANRE and EOR’s. --- Support this podcast: https://anchor.fm/scott--shapiro/support
Acute pancreatitis can be a devastating disease. Complications of pancreatitis can be minimized by appropriate early, initial management. Joe Hines, MD, and Raman Muthusamy, MD, from UCLA discuss the recent American Gastroenterological Association guideline on managing acute pancreatitis. Related Article(s): Initial Management of Acute Pancreatitis
Acute pancreatitis is an acute inflammatory disease of the pancreas which is reversible. There are several causes, the most common of which are gallstones and alcohol ingestion. In this podcast we discuss the causes of acute pancreatitis, it's severity staging and management thereof. Stanleur Capital: Medical practice and personal financial solutions · Acute pancreatitis .pdf — PDF (640.5 KB)
Acute pancreatitis is an acute inflammatory disease of the pancreas which is reversible. There are several causes, the most common of which are gallstones and alcohol ingestion. In this podcast we discuss the causes of acute pancreatitis, it's severity staging and management thereof. Acute pancreatitis .pdf — PDF (640.5 KB)
06/29/2020 | MDCT of Acute Pancreatitis Part 2
06/22/2020 | MDCT of Acute Pancreatitis Part 1
Acute Pancreatitis: What is it? What are the Symptoms, Diagnosis, Treatment, Complications, and Prevention strategies. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/drnikkifnp-bc/support
In today's VETgirl online veterinary continuing education podcast, we will be reviewing a treatment that is often a bit controversial -; steroids! In particular, we will look at the use of steroids in the treatment of acute pancreatitis in dogs. Steroids may appear attractive to use in this inflammatory disease since glucocorticoids impart anti-inflammatory affects in the body. Glucocorticoids may theoretically improve pancreatic blood flow and in critically ill patients with refractory blood pressure concerns, glucocorticoids are sometimes used to treat suspected (or confirmed) CIRCI. But with the possibility of eliciting negative side effects from steroid use, owing to their unwanted gastrointestinal tract side effects and their immunomodulatory effects, are they worth the risk in treating these patients?
In today's VETgirl online veterinary continuing education podcast, we will be reviewing a treatment that is often a bit controversial -; steroids! In particular, we will look at the use of steroids in the treatment of acute pancreatitis in dogs. Steroids may appear attractive to use in this inflammatory disease since glucocorticoids impart anti-inflammatory affects in the body. Glucocorticoids may theoretically improve pancreatic blood flow and in critically ill patients with refractory blood pressure concerns, glucocorticoids are sometimes used to treat suspected (or confirmed) CIRCI. But with the possibility of eliciting negative side effects from steroid use, owing to their unwanted gastrointestinal tract side effects and their immunomodulatory effects, are they worth the risk in treating these patients?
In this episode, Dr Chacko & I discuss various controversies associated with nutrition in acute pancreatitis.
SCORE Modules Covered: Diseases/Conditions: Pancreatitis - Acute/Pancreatic Necrosis/Abscess (Core), Operations/Procedures - Pancreatic Debridement (Core)
The UK incidence of acute pancreatitis is estimated as 15–42 cases per 100 000 per year and is rising. It has a mortality rate of 1%–7% which increases to around 20% in patients with pancreatic necrosis. In this podcast, Trainee Associate Editor of Frontline Gastroenterology James Maurice talks to Dr Gavin Johnson (Department of Gastroenterology, University College Hospital, London) about the current diagnostic and management challenges in acute pancreatitis. Read the article on the FG website: https://fg.bmj.com/content/10/3/292.
Medbullets.com: acute pancreatitis
Ajánlott irodalom: Verstraete, S., Verbruggen, S. C., Hordijk, J. A., Vanhorebeek, I., Dulfer, K., Güiza, F., … Jacobs, A. (2019). Long-term developmental effects of withholding parenteral nutrition for 1 week in the paediatric intensive care unit : a 2-year follow-up of the PEPaNIC international , randomised , controlled trial, 7(February), 141–153. https://doi.org/10.1016/S2213-2600(18)30334-5 Marik, P. E. (2014). Enteral nutrition in the critically ill: Myths and misconceptions. Critical Care Medicine, 42(4), 962–969. https://doi.org/10.1097/CCM.0000000000000051 Martinez, E. E., Ariagno, K., Arriola, A., Lara, K., & Mehta, N. M. (2015). Challenges to nutrition therapy in the pediatric critically ill obese patient. Nutrition in Clinical Practice, 30(3), 432–439. https://doi.org/10.1177/0884533615569887 Fitz-gibbon, S., Tomida, S., Chiu, B., Nguyen, L., Du, C., Miller, J. F., … Weinstock, G. M. (2014). The Management of Acute Pancreatitis in the Pediatric Population: A Clinical Report from the NASPGHAN Pancreas Committee Maisam, 133(9), 2152–2160. https://doi.org/10.1038/jid.2013.21.Propionibacterium
Get our free clinical lab guide: https://www.medgeeks.co/labguide - We have a 32 year old male with a past medical history of ETOH abuse (1 pint of vodka daily), ETOH related seizures, and hypertension. He presents with a complaint of severe epigastric pain and tenderness which started about a day ago and has progressively worsened over the day. The patient said he attempted to eat and drink this morning, but became nauseous and had one episode of non-bloody vomiting. The patient's last alcoholic drink was the night prior. He has no new medications. Vitals: 101.1F, HR 110, BP 89/68, 98% O2 sat RA. On exam, there is significant epigastric tenderness. But, no rebound or gaurding or peritoneal signs. Labs: WBC 15.4, H/H 15.7/43.5, platelets 188, BUN:Cr 10:1, Lipase is 2,806, and lactate of 10.3 Electrolytes, bilirubin, LFT, triglycerides normal. Today, we'll be breaking down acute pancreatitis. - Follow us on Instagram here: https://www.instagram.com/medgeeksinc - Check out our course material here: https://learn.medgeeks.co - This podcast should not be used in any legal capacity whatsoever, including but not limited to establishing standard of care in a legal sense or as a basis for expert witness testimony. No guarantee is given regarding the accuracy of any statements or opinions made on the podcast, video, or blog.
John Windsor talks about acute pancreatitis.
Combined Analysis of Three Large Interventional Trials With Gliptins Indicates Increased Incidence of Acute Pancreatitis in Patients With Type 2 Diabetes. Diabetes Care. 2017 Feb;40(2):284-286
Medical Basics Podcast - Tips, Tricks, and Advice for Medical and Nursing Students
In this podcast we talk about our approach to Acute Pancreatitis. We are also going to touch base on diagnosis, grading, the different etiologies and the utility of imaging and various prognostic tools. Be sure to check out medicalbasics.com for more educational resources! If you prefer video, check out the youtube video: https://youtu.be/HEaHPeWlhQI
Dr. Christian Jones takes us step by step on surgical options for acute pancreatitis. Follow Dr. Jones on Twitter @jonessurgery or check him out here https://jonessurgery.com/ Step Up Approach NEJM 2010 http://www.nejm.org/doi/full/10.1056/NEJMoa0908821
Dr. Maisam A. Abu-El-Haija acute pancreatitis presentation, she is the medical director of pancreas care center, division of pediatric gastroenterology at Cincinnati Children's Hospital, with participation from some experts and audience
Fred Gorelick
Fred Gorelick
11/09/2015 | MDCT Evaluation of Acute Pancreatitis Part 2
11/02/2015 | MDCT Evaluation of Acute Pancreatitis Part 1
This episode offers some advice in thinking about the very difficult topic of pancreatic pseudocysts. Some philosophical waxing about pain control and some items not addressed in the previous episodes are also discussed.
Imaging, fluid resuscitation, fine needle aspiration, determining sterile vs infected necrosis, and suggestions from the guidelines are discussed.
This episode addresses some of the debates regarding nutrition timing in acute pancreatitis. Methods such as nasogastric, nasojejunal, and oral feeding are compared.
Tierärztliche Fakultät - Digitale Hochschulschriften der LMU - Teil 07/07
Sat, 18 Jul 2015 12:00:00 +0100 https://edoc.ub.uni-muenchen.de/19055/ https://edoc.ub.uni-muenchen.de/19055/1/Stumpf_Franziska.pdf Stumpf, Franziska ddc:590, ddc:500, Tierärztliche Fakultät
Louisville Lectures Internal Medicine Lecture Series Podcast
Dr. Jason Roberts is an Assistant Professor of Medicine and the Director of Endoscopy in the Department of Gastroenterology at the University of Louisville. In this lecture, he discusses the management of Acute Pancreatitis and his perspectives on whether is is a primarily surgical or medical diagnosis. His faculty profile can be found here: http://louisville.edu/medicine/departments/medicine/doctors/roberts-jason Â
This episode focuses on the nutritional management of acute pancreatitis in dogs and cats answering questions such as: When should we be providing nutrition to dogs and cats with acute pancreatitis? Should we be using enteral or parenteral nutrition? Should we be using post-pyloric jejunal feeding or is oral or gastric feeding okay? The episode is largely based around the following clinical practice review article: Jensen KB, Chan DL. Nutritional management of acute pancreatitis in dogs and cats. J Vet Emerg Crit Care 2014. 24(3):240-250. As mentioned in the episode, if you would like a FREE copy of some general notes on acute pancreatitis in dogs and cats that cover more than 'just' the nutritional aspects, please click the link below and follow the instructions: Get your FREE copy of notes on acute pancreatitis In the episode I also mention a blog post on syringe feeding which you can find HERE. One paragraph from the paper that I read out in the episode and promised to include here was as follows: “The traditional approach to AP centered on the premise that withholding food would reduce pancreatic autodigestion by decreasing pancreatic stimulation and enzyme release. However, the pathogenesis of pancreatitis more likely involves premature intracellular activation of proteolytic enzymes rather than pancreatic stimulation. Avoidance of feeding as a means to decrease pancreatic stimulation may be unwarranted and could lead to malnutrition and impaired gastrointestinal barrier function. Lack of enteral nutrition results in the loss of normal physiologic intestinal motility, is associated with intestinal villus atrophy, and compromises intestinal mucosal blood flow. If sustained, the lack of enteral nutrition could lead to a compromise of local immunoglobulin and biliary salt production with consequent disruption of normal internal bacterial flora and gastrointestinal barrier function. It also has been demonstrated in experimental rodent models and in people with naturally occurring disease that exocrine pancreatic secretion actually decreases during pancreatitis and that the decrease is more pronounced with increasing severity of inflammation. The practice of withholding food for several days from the time of initiation of therapy may prove detrimental as a period of anorexia often precedes the initial clinical presentation to veterinarians in patients with AP. Implementation of nutritional support may be critical for successful management of patients with AP.” And the list of summary points from the paper is as follows: There is increasing evidence supporting the important role of early EN (ideally within 48 h of diagnosing pancreatitis) in positively impacting outcome in patients with AP. Nutritional support is an integral and key aspect of the successful management of AP. The use of enteral feeding in veterinary medicine is now considered to be safe, effective, and well-tolerated in severe AP. Enteral nutrition is less expensive than parenteral feeding and helps to maintain gastrointestinal mucosal function, and therefore is likely to have a beneficial influence on the disease course. Use of NG, nasoesophageal, jejunal, and oesophagostomy feeding tubes is effective and safe in dogs and cats and should be used unless specific contraindications are identified. There is no evidence at this time to support the superiority of post-pyloric jejunal feeding over oral or gastric feeding. The optimal enteral diet for patients with AP has not been identified, but diets commonly used for convalescing dogs and cats can be used. Avoidance of enteral diets with high fat content does not appear to be necessary in the majority of patients. Despite the growing evidence that EN can be used effectively in the management of patients with AP, there may still be patients that require some form of PN until sufficient EN can be tolerated. And of course we have the usual and completely reasonable conclusion that future veterinary studies investigating feeding routes, dietary composition, and optimal timing of nutritional support in AP are warranted.
Louisville Lectures Internal Medicine Lecture Series Podcast
Dr. Parajuli is an Assistant Professor and Director of the Gastroenterology, Hepatology, and Nutrition Fellowship. Here he discusses an approach to pancreatitis. His faculty profile can be found here: http://louisville.edu/medicine
Causes, symptoms, morphology and complications of acute pancreatitis
Objectives: This study aimed to explore the period between onset of pain and hospital-admission (pain-to-admission time) in patients with acute pancreatitis (AP), to investigate the prognostic value and associated factors of this time, and to ascertain the knowledge about the pancreas in these patients. Methods: An analysis of a prospective multicenter study was done, which included 188 patients with AP. Results: Median pain-to-admission time was 27 hours (interquartile range, 6.0-72.0). Median pain-to-admission time was significantly shorter in intensive care unit (ICU) patients (10 hours) compared to non-ICU patients (36 hours) (P = 0.045). Short pain-to-admission time was associated with high pain level. Median pain level (0, no pain; 10, maximal pain) was 8.0 (interquartile range, 7.0-10.0). Older age correlated with lower pain level (r = -0.26; P = 0.002). Multiple logistic regression analysis including the admission values for serum lipase and C-reactive protein and the corresponding interactions to the pain-to-admission time showed substantial discriminative ability regarding ICU admission (concordance index, 0.706; P = 0.006). 86% (112/130) knew that they have a pancreas, 72% (81/112) of these patients knew that AP exists, and 56% (45/81) recognized that AP is potentially fatal. Conclusions: Knowledge about AP in hospitalized AP patients is poor. Serum lipase and C-reactive protein in dependency of the pain-to-admission time might be a suitable predictor for severity of AP.
Mairi McLean, Gut’s education editor, talks to Peter Banks, Division of Gastroenterology, Hepatology, and Endoscopy, Harvard Medical School, and Michael Sarr, Department of Surgery, Mayo Clinic, Rochester, about their revision of the Atlanta classification of acute pancreatitis.See also:Classification of acute pancreatitis—2012: revision of the Atlanta classification and definitions by international consensus (http://tinyurl.com/arb6fg6)
Objectives: The anti-inflammatory effects of O-1602 and cannabidiol (CBD), the ligands of G protein-coupled receptor 55 (GPR55), on experimental acute pancreatitis (AP) were investigated. Methods: Acute pancreatitis was induced in C57BL mice by intraperitoneal injection of 50 mu g/kg cerulein hourly, with a total of 6 times. Drugs (O-1602, 10 mg/kg, or CBD, 0.5 mg/kg) were given by intraperitoneal injection 2 times at 30 minutes before the first injection and immediately before the fifth cerulein injection. At 3 hours after the last injection, the blood, the lungs, and the pancreas were harvested for the pancreatic enzyme activity, myeloperoxidase activity, and pro-inflammatory cytokines measurement; and the expressions of GPR55 mRNA and protein in the pancreas were detected. Results: Cannabidiol or O-1602 treatment significantly improved the pathological changes of mice with AP and decreased the enzyme activities, IL-6 and tumor necrosis factor alpha levels, and the myeloperoxidase activities in plasma and in the organ tissues. G protein-coupled receptor 55 mRNA and protein expressed in the pancreatic tissue, and the expressions were decreased in the mice with AP, and either CBD or O-1602 attenuated these changes to a certain extent. Conclusion: Cannabidiol and O-1602 showed anti-inflammatory effects in mice with AP and improved the expression of GPR55 in the pancreatic tissue as well.
A study in the December issue of Gastroenterology finds that among patients with pancreatic sphincter dysfunction, biliary sphincterotomy or a combination of biliary and pancreatic sphincterotomy similarly prevent acute pancreatitis; with Dr. Gregory Cote
Robb Wolf - The Paleo Solution Podcast - Paleo diet, nutrition, fitness, and health
Topics: [5:41] Absolute Optimal Human Diet [14:24] Reading Recommendations [21:15] Surviving a Month as a Vegan [24:54] Potentially Allergenic Food Introduction For Babies [34:14] Antiperspirant Deodorant and Carbonated Water [39:05] Post Activation Potentiation [48:45] Non-Hodgkin’s Lymphoma [59:14] Acute Pancreatitis and Paleo
Dr. Timothy B. Gardner discusses his manuscript "Early Fluid Resuscitation Reduces Morbidity Among Patients With Acute Pancreatitis." To view the print version of this abstract go to http://tiny.cc/rye14
Early Fluid Resuscitation Reduces Morbidity Among Patients With Acute Pancreatitis; Lactated Ringer's Solution Reduces Systemic Inflammation Compared With Saline in Patients With Acute Pancreatitis. Dr. Kuemmerle interviews author Dr. Timothy B. Gardner
A brief discussion of the considerations of ICU care of the patient with severe pancreatitis, fluid resuscitation, respiratory, renal, and nutrition.
In this episode, Dr Jonathan White provides a beginner's guide to acute pancreatitis. Learning points include: Recognising the patient with pancreatitis Making the diagnosis Causes of pancreatitis How to manage the patient with pancreatitis Running time: 20:56
Two clinical scenarios in the “Education Practice” section of May's CGH look at approaches to acute pancreatitis during stages of early management and follow-up, respectively. Dr. Kuemmerle speaks with author Dr. Bechien U. Wu.
Background: Pancreatic infiltration by leucocytes represents a hallmark in acute pancreatitis. Although leucocytes play an active role in the pathophysiology of this disease, the relation between leucocyte activation, microvascular injury and haemorrhage has not been adequately addressed.Methods: We investigated intrapancreatic leucocyte migration, leucocyte extravasation and pancreatic microperfusion in different models of oedematous and necrotising acute pancreatitis in lys-EGFP-ki mice using fluorescent imaging and time-lapse intravital microscopy.Results: In contrast to the current paradigm of leucocyte recruitment, the initial event of leucocyte activation in acute pancreatitis was represented through a dose- and time-dependent occlusion of pancreatic capillaries by intraluminally migrating leucocytes. Intracapillary leucocyte accumulation (ILA) resulted in dense filling of almost all capillaries close to the area of inflammation and preceded transvenular leucocyte extravasation. ILA was also initiated by isolated exposure of the pancreas to interleukin 8 or fMLP, demonstrating the causal role of chemotactic stimuli in the induction of ILA. The onset of intracapillary leucocyte accumulation was strongly inhibited in LFA-1-/- and ICAM-1-/- mice, but not in Mac-1-/- mice. Moreover, prevention of intracapillary leucocyte accumulation led to the development of massive capillary haemorrhages and transformed mild pancreatitis into lethal haemorrhagic disease.Conclusions: ILA represents a novel protective and potentially lifesaving mechanism of haemostasis in acute pancreatitis. This process depends on expression of LFA-1 and ICAM-1 and precedes the classical steps of the leucocyte recruitment cascade.
Remarkably elevated levels of phospholipase A(2) (PLA(2)) are measurable in human blood samples in cases of acute pancreatitis. The source of the enzyme was first thought to be exclusively the pancreas, but now it is generally accepted that two isoenzymes the pancreatic PLA(2), group I, and the extrapancreatic PLA(2), group II contribute to the raised activity. In contrast to the group II-PLA(2), the pancreatic PLA(2) is heatresistant for 1 hour at 60 degreesC. The catalytically inactive proenzyme of the pancreatic PLA(2) can be activated by trypsin. The aim of our study was to evaluate the diagnostic value of PLA(2) isoenzyme activity measurements to identify patients with severe complications in acute pancreatitis. Blood samples from patients suffering from acute pancreatitis were analyzed for catalytically active pancreatic PLA(2) on day 1 and 2 of hospitalization with a modified radiometric Escherichia colibased PLA(2) assay. In 10 of 41 patients clearly elevated values of catalytically active, heatresistant pancreatic PLA(2) (7.2 to 81.2 U/l) were observed. This group of patients was characterized by severe complications (necrotizing pancreatitis, shock, sepsis, respiratory problems) of which two patients subsequently died. Patients with low or undetectable activity (
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