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Your gut lining rebuilds itself every five days — faster than any other tissue in your body — and that turnover rate is either your best defense or your biggest vulnerability, depending on what you're doing to it. In the final episode of this series with stem cell scientist and STEMREGEN founder Christian Drapeau, Eric Malzone digs into why the intestinal lining is "the most fragile and vulnerable part of your body," how estrogen withdrawal at menopause quietly wrecks gut repair, and why Christian believes the real story of aging isn't inflammation or free radicals — it's a failure of the body's own repair system. They also get into a jaw-dropping 1940s case study on gut bacteria and psychosis, the specific bacteria linked to autoimmune disease and diabetes, and why Christian thinks "stem cells bring cure" is the hardest sentence in modern medicine. Key Takeaways
Why are so many young women experiencing painful periods, endometriosis, Hashimoto's and hormonal chaos? After falling ill with Graves Disease in medical school, functional endocrinologist Dr. Cassie Smith made it her life's mission to chase these kinds of questions. In her new book Fix Your Gut, Fix Your Hormones (https://a.co/d/0gbCrVD6) she tackles the real gut-hormone connection behind estrogen dominance, PCOS, thyroid dysfunction, and painful periods. Dr. Smith shares the answers she found, a roadmap for better health, better periods and common-sense steps to become the CEO of your own health. In this episode you will learn: Why younger women are struggling with their periods Why low progesterone is so common in women in their 20s How constipation and poor fiber intake worsen PMS, bloating, and breast tenderness The impact of long-term birth control use on hormone production Simple, affordable lab tests most OBs don't order but should Exactly how your gut affects your hormones, step by step, by way of your vagus nerve. How a young person could experience a cycle of stress, a bacteria or strep infection, then their antibiotics for treating the strep as well as birth control and acid-blockers can impair their guts affecting their cycle. How, if, as women, our estrogen leaves our body down the four-hydroxy pathway (the pathway that can lead to cancer), more often when we have increased visceral fat, excess stress or intense gut dysbiosis. How important our health is, and the value in taking responsibility for our good health. Self-value, seeing the sun enough in a day and movement all play a role in balancing our hormones. Not only can excess estrogen affect our moods, but it puts extra stress on our bodies revving up our cortisol and lowering progesterone (the calming hormone), throwing our mood and sleep out the window. Nutritional changes can make a difference. Avoid sugar in your food and drinks (read the labels!), and aim for thirty-five grams of fiber for regular, healthy bowel movements. Estrogen dominance from dysbiosis doesn't necessarily mean you have enough of the estrogen you need. How having a Dutch test every few years is incredibly useful for locating early signs of hormonal imbalances. A roadmap to fix painful periods. Laser in on how much sugar you're eating (and drinking!) Don't eat wheat made in America if you have Hashimotos, because it may cause a high TPO antibody to attack your thyroid. How babies rely on their mother's thyroid until 18 weeks in-utero, so if you want to get pregnant, optimizing your thyroid is a must. Want more of The Ancient Health Podcast? Subscribe to the YouTube channel. ------ Follow Doctor Motley! Instagram TikTok Facebook Website Follow Dr. Cassie Smith: https://www.instagram.com/modernendocrine_/ Buy her book Fix Your Gut, Fix Your Hormones: https://a.co/d/0gbCrVD6 ------ *You can get cell support in gummy form: Mitopure now starts at $79, when you go to timeline.com/DRMOTLEY. *Join Doctor Motley's newsletter for TCM insights and regular podcast updates https://www.doctormotley.com/ *Do you have a ton more in-depth questions for Doctor Motley? Check out his course on emotions and the body in his membership. You'll find other courses full of his expertise and clinical wisdom, plus bring all your questions to his weekly lives! To try risk-free for 15 days click here https://www.doctormotley.com/15
If you are taking HRT, it is not enough to only ask how much estrogen you are using. You also have to ask a second question: how well is your body actually processing and clearing that estrogen? In this episode, I sit down with David Roberts and John Gilday from Mara Labs to unpack estrogen metabolism, estrogen receptors, environmental hormone disruptors, detoxification pathways, and why the conversation around "estrogen dominance" is often way too simplistic. We talk about the difference between having high estrogen and having estrogen that is not being metabolized efficiently, especially in perimenopause when estrogen can fluctuate wildly while progesterone starts dropping. We also get into xenoestrogens, microplastics, estrogen metabolites, the body's phase one, phase two, and phase three detoxification pathways, and why compounds like sulforaphane, resveratrol, black cohosh, and curcumin have become so interesting in the conversation around midlife health. The big message here is that hormone optimization is not always about adding more. Sometimes it is about making sure the body has the tools it needs to use, metabolize, and eliminate hormones effectively. In this episode, we cover: What "estrogen dominance" can actually mean in perimenopause Why low progesterone can change the way estrogen affects the body Estrogen receptor alpha versus estrogen receptor beta How xenoestrogens and endocrine-disrupting chemicals may interfere with hormonal signaling Why estrogen metabolism matters whether your estrogen is natural or coming from HRT Phase one, phase two, and phase three detoxification explained Why genetics may affect how efficiently women metabolize estrogen What sulforaphane is and why broccoli sprouts get so much attention Sulforaphane vs DIM for estrogen metabolism The roles of resveratrol, black cohosh, carnosic acid, and curcumin Why inflammation, oxidative stress, and detoxification are all connected How supplements may fit into a broader midlife hormone strategy For the next week, Hormone Solution loyal listeners can get an exclusive 25% off all Mara Labs products when you go to mara-labs.com/HORMONES use code HORMONES at checkout. After one week, the code will return to the standard 15% off. Sponsors Book your FREE hormone strategy call with one of Midlife Solutions team members and find out how we can help you! Book here. Get started today in our Midlife Reset RX program! Get 20% off your Cozy Earth Bed Sheet with coupon code HORMONES Order your LMNT electrolytes today and get a FREE 8 pack of samples! Plus try it risk free, they have a no-questions-asked refund policy – you don't even have to send it back! Are you in perimenopause or postmenopause and struggling with symptoms—but not getting the support you deserve? At Midlife Solutions, we specialize in hormone optimization for women in midlife. Our all-female clinical team offers telehealth care across all 50 U.S. states, with the ability to prescribe bioidentical estrogen, progesterone, testosterone, and thyroid medication. Book your FREE Hormone Discovery Call Find out what's really driving your symptoms and what your next best steps are. Visit the website: https://karenmartel.com Shop the Midlife Solutions Store Over-the-counter bioidentical hormone creams and oils — no prescription needed. Including: • Progesterone • Estrogen Face Cream • Vaginal Moisturizer and more! Take the Hormone Quiz Discover hidden hormone imbalances that could be driving your symptoms. Get personalized results (and yes, they may surprise you). Women's Peptide Weight Loss Program Clinically guided, hormone-aware weight loss for midlife women. Midlife RESET HRT Program A complete, supportive approach to hormone replacement therapy in midlife. Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert Karen's Facebook Karen's Instagram
How Long Does It Take You to Wake Up? The Cortisol Cheater Question You hit snooze six times. You need two cups of coffee before you can hold a conversation. Or the opposite: your eyes open at a level ten, heart already going, anxiety already running. There is a name for what is happening, and there is a test for it. Dr. Terri sits down with Carrie Jones, ND, FABNE, MPH, MSCP, the naturopathic physician known as the Queen of Hormones, for a conversation about the hormone testing almost nobody is ordering. Not blood. Not saliva. Urine metabolites, which show you not just how much of a hormone you have, but where it goes after your body is finished with it. Because that turns out to be the part that matters. Estrogen can travel down three different pathways, and one of them is protective while another is genotoxic. Testosterone can convert into something far more potent, which is why some women get hair loss and jawline acne on a dose that works beautifully for someone else. Progesterone can knock one woman out in ten minutes and do almost nothing for the woman next to her on an identical dose. None of that shows up on a standard panel. They also spend real time on cortisol, which has become the most misunderstood hormone on the internet. Dr. Carrie makes the case that we are doing to cortisol exactly what we did to estrogen after the Women's Health Initiative: blaming the messenger, missing the message, and reaching for supplements to suppress something the body is doing on purpose. This one is for anyone who has been told their hormones are fine, or who has tried hormone therapy and quit because of side effects nobody could explain. What you'll discover: What urine metabolite testing actually measures, and why hormones have to go somewhere (02:03) The three estrogen pathways, and which one you want to push toward (04:45) The pathway that explains breast tenderness, spotting, and estrogen sensitivity (07:58) Why testosterone causes acne and hair loss in some women and not others (09:23) Alpha versus beta: why two women on the same progesterone dose have completely different nights (11:16) Whether the route you take progesterone changes the effect (14:20) What cortisol metabolites reveal about your thyroid that a TSH will not (19:39) Free T3, reverse T3, and reference ranges that are normal but not optimal (21:39) Poor, poor cortisol: what it is actually doing for you, and why we get it backward (26:29) The everyday medications quietly suppressing your cortisol results (30:11) Serum, saliva, or urine: which cortisol test answers which question (34:57) The cortisol awakening response, and the cheater question you can answer yourself (36:24) When a urine metabolite panel is worth the money, and when it is not (40:22) Cruciferous vegetables, DIM, and the caution nobody gives you before you start (42:39) Supplements that support the DHT pathway, and why sourcing decides whether they work (47:01) Alcohol as a bully: how the liver decides what gets detoxified first (52:55) You are not stuck with the hormone you were dealt. You are working with a pathway, and pathways are modifiable. The Dr. Terri Show is presented by EVEXIAS Health Solutions. For more, visit: https://www.evexias.com Connect with Dr. Terri:
For decades, women with low bone density were told to take it easy; Professor Belinda Beck's research proved the opposite: high-intensity resistance and impact training safely rebuilds bone, even in women who had been told their bones were too fragile to lift heavy. Belinda covers the full arc of bone health, from how peak bone mass is set in the teenage years, to what actually happens to bone when estrogen declines through perimenopause and menopause, to why so many popular "safe" exercises, including walking, cycling, and Pilates, simply don't provide enough stimulus to protect bone. They dig into the physiology of bone remodelling, the real evidence (and lack of it) behind weighted vests, how to read a DEXA scan, and practical calcium and vitamin D guidance. Belinda also shares the story behind LIFTMOR itself, including how her research team was once considered reckless for asking postmenopausal women to lift heavy, and how those same women ended up stronger, more confident, and more independent than they'd been in decades. EPISODE OVERVIEW (00:00) Introduction & Rapid Fire (05:15) Bone 101: Structure, Types & What Determines Density (11:52) How Bone Forms: Peak Mass, Sex Differences & Sesamoid Bones (17:12) Diet Culture, Dairy Myths & Caloric Restriction (23:42) Debunking the Kids & Weightlifting Myth (28:31) Runners, Multi-Sport & Varying the Stimulus (34:51) Wolff's Law & How Bone Adapts to Load (42:22) Best & Worst Exercises for Bone, Weighted Vests & Pilates (50:08) Estrogen, Perimenopause, Menopause & Building Your Baseline (1:04:16) The LIFTMOR Trial, ONERO & Getting Your Life Back (1:16:16) The After Party: Final Thoughts with Dr. Stephanie RESOURCEShttps://drstephanieestima.com/podcasts/ep483 OUR SPONSORS LMNT Stay hydrated without the sugar, food dye, and other dodgy ingredients found in popular electrolyte and sports drinks. Get a special offer when you make a purchase at https://DrinkLMNT.com/Better BEARABY Find a more natural way to support deeper, calmer sleep. Go to https://bearaby.com and use code BETTER10 for 10% off any Bearaby weighted blanket purchase. YOUNG GOOSE Skin aging isn't defined by wrinkles. It's defined by skin quality. Head over to https://drstephanieestima.com/younggoose and use code BETTER for 10% off your first purchase. TIMELINE Timeline's clinically proven formula is now available at a great price when you go to https://timelinenutrition.com/better with code BETTER. ****************************P.S. When you're ready, here are two ways Dr. Stephanie can help you:Subscribe: The Mini Pause — My weekly newsletter packed with the most actionable, evidence-based tools for women 40+ to thrive in midlife.Build Muscle: LIFT — My progressive strength training program designed for women in midlife. Form-focused, joint-friendly, and built for real results. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Vigorous Steve, Dr. Dean St. Mart, & Kurt Havens join the chat.APR Health Solutions Peptides: www.aprhealthsolutions.com - code nyleOptimize HRT Clinic: https://members.optimize-hp.com - code nyleMerch: https://www.aykons.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'nyle' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘nyle' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program: https://www.nylenaygafitness.com00:00:00 - Intro00:05:17 - What We Knew Before Our First Cycle00:16:18 - Genomic vs Non-Genomic Steroid Pathways00:22:48 - mTOR, Leucine & Protein Timing00:25:20 - Preserving Muscle & Blocking Cortisol00:28:00 - Caloric Cost of Muscle & Aging00:31:08 - The High Protein Myth on Gear00:36:58 - Kidney Health, Blood Pressure & EQ00:40:47 - Epicatechin, Injectable YK-11 & Inflammation00:45:00 - Mitochondrial Peptides & Leaky Gut00:50:50 - Follistatin & Myostatin Inhibitors00:57:01 - Steroids You Should Avoid01:06:14 - Mental Health Regrets & Tren Aggression01:13:28 - Retiring & Detaching Your Ego01:17:05 - Finding Identity Outside Bodybuilding01:22:36 - Custom Stacks vs Cookie-Cutter Protocols01:30:20 - The Evolution of Safer Bodybuilding01:33:57 - Extreme Fat Loss: ATX-304, BAM15 & DNP01:39:26 - Is Insulin Actually Necessary?01:43:30 - Blood Sugar Myths & Morning Hydration01:53:08 - Growth Hormone: Men vs Women02:00:47 - Hematocrit, Estrogen & Phlebotomy Myths02:12:53 - Injection Frequency & Patient Compliance02:17:52 - GLP-1 Dosing: Retatrutide & Tirzepatide02:28:39 - Peptide Stacks & Intranasal Xenatide02:31:00 - The Ultimate Hair Loss Protection Stack02:41:30 - Final Advice
Five signs of fatty liver that are easy to miss, because they look like ordinary life. Nurse Doza walks through low energy, weight around the midsection, a fast-food pattern, hormone symptoms, and gallbladder issues, and explains what each one suggests about the liver underneath. Plus the two labs worth asking your provider about, the foods that ease the load, and where to start. Nothing here is a diagnosis. Featured Product Liver Boost (Detox) — $111 Liver Boost is a comprehensive formula designed to support phase I and phase II liver detoxification, with nutrients that support your antioxidant systems and glutathione production. If this episode had you thinking about how much your liver handles in a day — fats, blood sugar, and everything your body needs to clear out — this is the formula built to support that work while you make the diet and lifestyle changes that move the needle. It is not a replacement for those changes.
Over 40 and suddenly struggling to lose fat or build muscle? It must be your hormones... right?Not so fast.Jumping straight to TRT, HRT, peptides, or GLP-1s could be solving the wrong problem.Jay Campbell, author of The Testosterone Optimization Therapy Bible and co-founder of BioLongevity Labs, breaks down where hormones actually fit into fat loss, muscle building, metabolism, and longevity.We cover why testosterone boosters usually disappoint, what free versus total testosterone can tell you, common mistakes with TRT, estrogen management, and why lifestyle still matters even when using therapeutic tools.Jay also shares his perspective on strength training over 40, building muscle for longevity, cardio and visceral fat, and the rapidly evolving world of GLP-1 medications and peptides.Join Eat More Lift Heavy to build strength, lose fat, and learn what works for your body, 1 week at a time. Learn to eat more and lift heavy with confidence. Timestamps:0:00 – Are hormones blocking your progress2:22 – How much hormones really matter9:35 – Testosterone boosters and marketing hype12:58 – Lifestyle versus therapeutic hormone tools17:45 – Jay's long-term TRT experience24:11 – Estrogen mistakes during testosterone therapy31:36 – Hidden signs of hormone deficiency41:40 – Muscle, cardio, and longevity52:59 – GLP-1s and what comes nextEpisode resources:Website & Resources: jaycampbell.com/free-info Book: LIVING LEANER LONGER STRONGER: The Blueprint for Optimal Health & LongevityBiolongevity Peptides & Supplements (Use code WITSANDWEIGHTS for 15% off)Facebook: @JayCampbell333Instagram: @jaycampbell1971Twitter: @JayCampbell333
What I Discussed With Dr Shamyra Howard...- What a man actually hears when his partner tells him she needs a toy to finish- The three words she gives every couple before they open the box- What happens to the clitoris once the estrogen goes, and why nobody warned us- The one question to answer before you look at a single product- What a manufacturer found when it stopped testing on twenty-five-year-olds- Why she keeps a box of lube next to her desk and gives it away to everyone- What a partner did with my vibrator that I have not stopped thinking about since- The belief about women's sexuality after 50 she would destroy tomorrowChapters00:00– Sponsor spotlight: https://www.ohmibod.com/00:28 – Breaking the silence on why midlife intimacy is due for a serious upgrade.02:06 – Looking at the outdated societal scripts and the hidden pleasure gap affecting mature women.04:11 – Why physical body changes after 50 make intimate aids essential tools rather than afterthoughts.05:10 – Why male partners often feel replaced by bedroom aids and the crucial mindset shift that changes everything.07:54 – How to smoothly invite a hesitant partner to explore intimate devices together without making it awkward.11:02 – The surprising clinical research showing how certain stimulation devices can actively reduce menopause symptoms.12:18 – Choosing the right sensation when navigating internal versus external stimulation options.13:53 – How targeted clitoral air technology is transforming arousal and natural blood flow in post-menopausal bodies.15:07 – Sponsor spotlight: GITM Playbook http://gitmplaybook.com/SUZANNE2015:53 – A compelling study on how regular orgasms can meaningfully protect and boost your mental health.17:17 – Creative ways to use a multi-use massage wand across the entire full body's erogenous zones with a partner.19:37 – Why investing in high-grade intimate wellness tools is just as essential as your regular self-care routine.20:12 – The non-negotiable rule about pairing the right body-safe lubricants with medical-grade silicone.22:04 – Overcoming the persistent stigma around dryness and why lubrication is basic physiology, not a personal failure.24:04 – Combining topical solutions with daily bedroom habits to turn intimate comfort into a completely seamless experience.25:50 – Letting go of performance anxiety and completely redefining what pleasure feels like after 50.26:48 – The single most damaging myth about ageing women's sexuality that needs to be completely dismantled.27:31 – Wrapping up with community resources and practical ways to keep prioritising your intimate life.Show NotesMost women over 50 were handed a script that said sex was something we provide rather than something we receive. Then our bodies changed, nobody explained why, and we quietly decided the problem was us.In this episode I'm joined by Dr Shamyra Howard, an award-winning sexologist and licensed therapist who founded On the Green Couch. She spends her working week with couples over 50 who cannot say one sentence out loud to each other, and she has heard every version of how that silence ends.I told her something I do not say often. I need a toy about 80% of the time to get there. I have also been with a man who told me toys were not coming into his bedroom, and that put more strain on the relationship than the toy ever could have. Shamyra explained what he was hearing that I had no idea he was hearing.She is just as direct about the industry. Most sex toy companies still design for the average twenty-five year old, and she names the two that stopped and started asking menopausal women what they actually want instead.There is no clinical distance in this conversation and no coyness either. If sex has quietly got harder and you have been waiting for it to sort itself out, this is the episode that tells you what you are waiting on.Listen, learn and enjoy.Key Takeaways- The oral medications for men release the brakes. Sex toys do the same job for women, and Shamyra's line for partners who feel replaced is that tools don't compete, they assist. The toy is a teammate, not a rival.- Estrogen, progesterone and testosterone all fall from around 50. Lubrication drops, clitoral sensation drops and arousal needs more input than it used to. Most male partners have never been told any of this, so they keep doing what always worked.- Invite, don't surprise. Bring your partner into the decision before the toy arrives, frame it as an us thing rather than a me thing, and be clear that if pleasure matters to both of you, this is not optional.- Do not start with the catalogue. Decide where you want the sensation first. Shamyra finds women over 50 are moving away from penetrative options and towards clitoral ones, which narrows hundreds of products to a handful.- Womanizer and We-Vibe are running their market research with menopausal and post-menopausal women rather than twenty-five year olds. Womanizer reports that users of one of its pleasure air devices experienced fewer menopause symptoms, including poor sleep and irritability.- Clitoral suction increases blood flow to the area, and blood flow is where the arousal problem sits. Plenty of women are not orgasming for the simple reason that they were never sufficiently aroused.- A wand earns its price outside the bedroom. Neck, shoulders, feet, behind the knees, the inside of the thighs, and on a partner's body too. Shamyra treats good toys the way we treat hair and nails, as something worth paying for.- Water-based lube only with silicone toys, or the material breaks down. Check the ingredients for glycerin. And needing lube is not a verdict on you or your partner. Wetness depends on hormones and arousal, and the hormones are leaving.About the GuestShamyra holds a Doctorate in Social Work, she's an international award-winning Sexologist, Professor, Licensed Clinical Social Worker, and AASECT Certified Sex Therapist who exposes people to what they're missing from intimacy, so they can have a great relationship and better sex!She's a sexuality media maven featured in major digital and television productions, such as CNN, VOGUE, The New York Times, Peacock, OWN and many more, and she's the Founder of On the Green Couch, where she helps people manage sexual issues, create their best relationships, and have amazing sex.About SuzanneSuzanne Noble is a sex and relationship expert, author, and host of the Sex Advice for Seniors podcast, one of the top-rated shows empowering people 50+ to embrace confident, joyful intimacy. Known for her candid, warm, and often humorous approach, Suzanne challenges age-related taboos, misinformation, and awkward conversations about sex after 50. She helps millions around the world navigate their sexual lives with pleasure, connection, and self-assurance. Because life is too short for bad sex... or silence about it.Connect With SuzanneInstagram: https://www.instagram.com/sexadviceforseniorsFacebook: https://www.facebook.com/sexadviceforseniorsTikTok: https://www.tiktok.com/@sexadviceforseniorsSubstack: https://www.sexadviceforseniors.comConnect with Dr Shamyra HowardWebsite: onthegreencouch.comInstagram: https://www.instagram.com/sexologistshamyraYouTube: https://www.youtube.com/@sexologistshamyraFacebook: https://www.facebook.com/shamyralcsw/Want More?Visit the Website: https://sexadviceforseniors.com — includes FREE guides and resources for better sex at any age.Free Downloadable Guide: 10 Most Overlooked Secrets to Better Sex PDF: https://subscribepage.io/suzannenoblefreebieSign Up for My FREE Newsletter: https://sexadviceforseniors.comCheck Out My Storefront for Better Sex: https://zaap.bio/stayfirmInterested in 1:1 Coaching or Custom Sex Advice for Seniors Sessions? https://tidycal.com/suzannenoble/30-minute-mentoringLovehoney discount code ADVICE15 for the toys and lubricants discussed in this episode.Related EpisodesWhy Sex Changes After 50 and What Nobody Tells You | ft. Dr. Jenn Kennedy - https://www.sexadviceforseniors.com/p/why-sex-changes-after-50-and-whatThe Surprising 69% of Women Unhappy in Sex... and How to Fix It | ft. Malia Lazu - https://www.sexadviceforseniors.com/p/the-surprising-69-of-women-unhappy This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.sexadviceforseniors.com/subscribe
Today, we are taking a deep dive into a medical truth thatsounds completely counterintuitive, almost upside down, based on everything you think you know about women's health. But here's the kicker: it's actually nothing new at all. For over two decades, ever since the landmark Women'sHealth Initiative (WHI) study made global headlines back in 2002, the blanket narrative surrounding menopausal hormone therapy has been clear and persistent: hormones equal breast cancer risk. But there is a massive asterisk in thatscience that got completely lost in the media noise. While combination therapy with conjugated equine estrogens paired with medroxyprogesterone acetate (CEE +MPA) did show an increased risk, the story for estrogen-only therapy (mainly CEE) in women wh had a hysterectomy is entirely different. In fact, an overwhelming mountain of growing data shows that estrogen-only therapy is protectiveagainst both breast cancer incidence and breast cancer mortality. In this episode, we're unpacking the latest high-level evidence that cements this crucial distinction. We'll examine the broad statistical landscape, including a comprehensive meta-analysis by Qing et al. (officially set for the December 2026 issue of Annals of Medicine, following its ahead-of-print release in March 2026). Their work breaks down how randomized controlled trial data consistentlypoint to estrogen-only therapy having a protective effect, in stark contrast to combination therapy. We'll also dive into a brand-new Clinical Perspective published in mid-August 2026 in Obstetrics & Gynecology (the Green Journal) by Drs. Andrew Kaunitz and Jason Wright. They call urgent attention to this phenomenon, highlighting RCT meta-analyses that demonstrate a 23% reduction in breast cancer incidence with estrogen alone (RR = 0.77), alongside striking cohort data showing a dramatic risk reduction even in high-risk populations, like carriers of the BRCA mutation. Listenin for details.1. Wu Q, Shen L, Hu S, Yang R, Wang Y, Xue D, SunY, Ma H, Dai Z. Relationship between menopausal hormone therapy and incidencerisk of breast cancer: systematic review and meta-analysis. Ann Med. 2026Dec;58(1):2640244. doi: 10.1080/07853890.2026.2640244. Epub 2026 Mar.2. Kaunitz, Wright. Menopausal Estrogen Therapy andRisk of Breast Cancer. Obstet Gynecol. Aug 20263. Chlebowski RT, Aragaki AK, Pan K, et al.Randomized Trials of Estrogen-Alone and Breast Cancer Incidence: AMeta-Analysis. Breast Cancer Research and Treatment. 2024. 4. Writing Group for the Women's Health InitiativeInvestigators. (2002). Risks and benefits of estrogen plus progestin in healthypostmenopausal women: Principal results from the Women's Health Initiativerandomized controlled trial. JAMA, 288(3), 321–333.
“Progesterone will hold up the mirror for you and show you about your habits. Estrogen is forgiving—progesterone is not.” For so many women with vestibular disorders, symptoms get dramatically worse right before their period or around ovulation, and the answer they’re usually given is “take birth control” or “drink more water.” That, of course, is not enough. I brought in Dr. Saru Bala, Naturopathic Doctor and Women’s Hormonal Health Specialist, to break it all down. Get ready to nerd out on all things hormones! In this episode, we’re talking about what hormones actually are, how your cycle phases impact your vestibular symptom, why your liver is way more important than you think, the estrogen-histamine-MCAS loop, and what bloodwork you should be asking for. In this episode, we'll dig into: What are hormones What to pay attention to with women's hormones The phases of your cycle What progesterone is reflecting back about your habits The basics that impact your hormones the most Bloodwork Dr. Saru recommends for her clients Why you want to get a full thyroid panel The liver’s role in hormone metabolism How to support your liver The estrogen-histamine loop How MCAS plays a role here Why gut & liver support are essential for histamine, MCAS, and hormone issues Why women are taking much longer to feel better than even 5 years ago If you take nothing else away from this, remember your hormones, liver, gut, and nervous system are all talking to each other. When you start supporting them, things are able to start changing. Meet: Dr. Saru Bala Dr. Saru Bala is a licensed Naturopathic Doctor with a degree from Bastyr University in Seattle, WA. Prior to attending medical school, she graduated from University of Texas at Austin where she received her bachelor’s degree in Neurobiology. She's done extra training in women’s health and naturopathic endocrinology and wants to talk to you about all things women’s health. Connect w/ Dr Saru Bala Website: https://www.drsarubala.com/ Instagram: https://www.instagram.com/drsarubala Facebook: https://www.facebook.com/periodpractice Period Solutions Academy: https://www.drsarubala.com/periodsolutionsacademy Links Mentioned: Vestibular Group Fit (code GROUNDED at checkout for 15% off!): https://thevertigodoctor.com/vestibular-group-fit Rise Centered Alarm Clock: https://risecentered.com?sca_ref=7113075.4mnDvPsCZ8H Free Resources: The 4 Steps to Managing Vestibular Migraine: https://thevertigodoctor.myflodesk.com/cb5js0y78n The PPPD Management Masterclass: https://thevertigodoctor.myflodesk.com/new-pppd What your Partner Should Know About Living with Dizziness: https://thevertigodoctor.myflodesk.com/partnership The FREE Mini VGFit Workout: https://thevertigodoctor.myflodesk.com/minifit The FREE POTS – safe Workouts: https://thevertigodoctor.myflodesk.com/pots Connect with Dr. Madison (@TheVertigoDoctor): https://instagram.com/thevertigodoctor Work with Dr. Madison: For 1:1 Vestibular Rehabilitation Therapy, email madison@thevertigodoctor.com Otherwise, I'll see ya in Vestibular Group Fit! Connect with Dr. Jenna (@dizzy.rehab.therapist): https://www.instagram.com/dizzy.rehab.therapist/ Learn about the Oak Method: http://thevertigodoctor.com/why-vestibular-group-fit Love what you heard?Consider leaving a review on your favorite podcast platform to help us reach more vestibular warriors like you! This podcast is for informational purposes only and may not be the best fit for you and your personal situation. It shall not be construed as medical advice. The information and education provided here is not intended or implied to supplement or replace professional medical treatment, advice, and/or diagnosis. Always check with your own physician or medical professional before trying or implementing any information read here. hormonal health, women’s health, naturopathic doctor, vestibular migraine, chronic dizziness, birth control, vestibular disorders, PMDD, what is optimal bloodwork, optimal lab values, thyroid panel, lifestyle changes, period problems, understand your period, gut liver and hormone connection
In this episode, I'm joined by Dr. Jenn Simmons, former breast surgeon, founder of Real Health MD and Perfection Imaging, author of The Smart Woman's Guide to Breast Cancer, and host of the Keeping A Breast podcast. Jenn spent years working inside conventional medicine before her own health crisis pushed her to question what she had been taught and look more closely at prevention, screening and the bigger picture of women's health.We talk about mammograms, breast imaging, hormones, functional medicine and why women deserve more information, context and choice when making decisions about their health. Jenn also shares why she believes prevention has to go far beyond early detection, and why becoming curious, asking better questions and taking an active role in your own care can be so powerful.Highlights:(06:31) - The personal mission that took Jenn from conventional breast surgery to challenging the status quo(11:11) - The health crisis that made her ask a completely different question: what if there's something more?(23:51) - Why no doctor can be the hero of your health story, and why that power ultimately belongs to you(27:48) - Jenn's perspective on mammograms, ultrasounds and why she believes women need more screening options(50:35) - Why early detection alone isn't enough, and what a more preventative approach could look like(57:24) - Hormone replacement, bio-individuality and why Jenn says one-size-fits-all prescribing is not enoughFor breast cancer screening: https://www.perfeqtionimaging.com/For help on your breast cancer journey: https://www.jennsimmonsmd.com/Jenn's book: The Smart Woman's Guide to Breast Cancer https://tinyurl.com/SmartWomansBreastCancerGuideConnect with Jenn:https://www.twitter.com/DrJennSimmonshttps://www.perfeqtionimaging.com/https://www.linkedin.com/in/jennifer-simmons-md-16198389/https://www.instagram.com/drjennsimmonshttps://www.instagram.com/drjennsimmonsQualia Mind - click hereCoupon Code: SHOCKANDYALL (15% off any purchase)Visit Nicole's on demand fitness platform for live weekly classes and a recorded library of yoga, strength training, guided audio meditations and mobility (Kinstretch) classes, as well: https://www.sweatandstillness.comGrab Nicole's bestselling children's book and enter your email for A FREE GIFT: https://www.yolkedbook.comFind Nicole on Instagram:https://www.instagram.com/nicolesciacca/Tik Tok: https://www.tiktok.com/@thenicolesciaccaFacebook: https://www.facebook.com/nicolesciaccayoga/Youtube:https://www.youtube.com/channel/UC1X8PPWCQa2werd4unex1eAPractice yoga with Nicole in person in Santa Monica, CA at Aviator Nation Ride. Get the App to book in: https://apps.apple.com/us/app/aviator-nation-ride/id1610561929Book a discovery call or virtual assessment with Nicole here: https://www.calendly.com/nicolesciaccaThis Podcast is proudly produced by Wavemakers Audio
(00:00:00) 229: Doctor W.H.O. on Lubes - A World Health Issue! (00:00:11) Welcome to Itchy and Bitchy (00:01:32) The Surprising Variety of Sex Lubricants (00:04:51) What Makes a Good Lubricant (00:09:51) Personal Preferences in Lubricant Selection (00:15:25) Types of Lubricants Explained (00:21:20) The Importance of Provider-Patient Communication (00:22:32) Legit or Bullshit: Sexual Health Quirks (00:28:19) Closing Remarks and Call to Action The Art of the Perfect Lube: Because Your Vagina Deserves a Craft CocktailNobody talks about personal lubricants the way they talk about a perfectly balanced Old Fashioned, and honestly that's a crime. Both require the right ingredients, the wrong ones will absolutely ruin the experience, and yet most people are just grabbing whatever's cheapest off the shelf with zero regard for the recipe. Turns out formulation matters enormously; pH balance, osmolality, silicone versus water base, parabens, glycerin - these are your bitters, your base spirit, your garnish.Get the ratio wrong and you're looking at irritation, infection, and a night that ends far earlier than planned. Just like a great bartender wouldn't dump corn syrup into a Negroni, your body deserves better than petroleum-based mystery ingredients.We're breaking down exactly what's in your bottle and why the right cocktail recipe changes everything.Visit itchyandbitchy.comItchy & Bitchy is the podcast for anyone who has ever felt dismissed, misdiagnosed, or gaslit by a broken medical system. Become a supporter of this podcast: https://www.spreaker.com/podcast/itchy-and-bitchy-podcast--4303608/support.Itchy & Bitchy: Have you felt dismissed, misdiagnosed, or gaslit by a broken medical system. From gut health, hormones, autoimmune disease, chronic pain, holistic health, and alternative medicine ... medical gaslighting, patient advocacy , or misdiagnosis we'll call that too. For chronic illness warriors, self-advocacy seekers: WE OFFER No BS
Welcome back to our weekend Cabral HouseCall shows! This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track! Check out today's questions: Katie: Hi! Love listening to the podcast and grateful you give a chance to submit questions! I had an allergic reaction on my face and neck a few months ago. Derm called it atopic dermatitis. This came on after a micro needling treatment. First and last unfortunately. That has all resolved now, but I'm left with this hypopigmentation around my mouth and neck (neck has the worst inflammation) where spots are white now, especially if I tan. Any suggestions on how to resolve this loss of pigment? Thanks!! Anonymous: Hi! I am 34 years old. I have always thought I have PMDD, after ovulation I feel more sad/depressed/anxious amongst other things. I also have very painful heavy periods for context if it's helpful. I noticed the last 3-4 months the symptoms I have leading up to my period have been changing. I have started sweating more, which also smells more which has never been an issue for me. I also feel a little nauseous for a few days before my period amongst other things that aren't coming to mind right now. I'm wondering if something could have shifted in me to cause this? Do you have any insight, if I could afford to test I would, but I was hoping you'd have some insight for me. Thank you so much. Trish: Hi Dr Cabral - I wrote in a few weeks ago asking the difference between Estrogen support and balance. The reason I'm not sure which one to use is I took your individual labs you offer for Estrogen and Progesterone. Results on both were in the yellow low range tip of red range. The email recommended I take progesterone support and Estrogen support but I was told I was estrogen dominant which I thought would mean I take Estrogen balance. This is why I'm confused as to which estrogen to take. I take all the other products the email protocol is recommending. Thanks for your advice. You are so appreciated for the work you do. Mohamed: Hey Dr.Cabral, hope all is well. My question is regarding Reverse Osmosis water and lower pH versus alkalinity (CaCo3). These two are different from my understanding, the alkalinity is the water's ability to buffer acid/resist changes in pH. If Aquatru RO water filters everything, the alkalinity would in theory be very minimal. In comparison, Gerolsteiner or other high Bicarb mineral water have higher buffering capability. I'm asking regarding my research into urine pH and tumor (microenvironment). I want to increase urine pH along with other strategies. Since tumor Microenvironemt (extracellular) is typically acidic. Want to try increasing alkalinity and observe via urine pH to enhance effect of other strategies such as diet etc. How can I increase alkalinity of water? and best foods? Paige: Hey Dr Cabral! I found I have some sort of bump over my liver April of 2024 seemingly superficial and I notice no symptoms or pain or discomfort with it is just annoying when I do yoga as it stays local but I can feel it move slightly in the local area. I just did a 21 day detox and felt like it may have gone down a little. I am going to be doing the big 5 test to determine any other underlined concerns that may help but just curious what you would do in my circumstance if anything. Thank you I greatly appreciate your time and knowledge Sir. Have a great day! Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions! - - - Show Notes and Resources: StephenCabral.com/3844 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!
Life Coach BFF Show | Episode 277 Thriving in Midlife: The Estrogen Patch Shortage, Decluttering Keepsakes & Midlife Dilemmas Hosts: Heather Pettey & Dr. Carol Lynn Episode Summary In this episode, Heather and Dr. Carol Lynn sit down for a fun, relatable, and candid conversation on navigating midlife chaos with humor and grace. From dealing with the real-life frustration of the current estrogen patch shortage to figuring out what to do with decades of family photos, old furniture, and childhood keepsakes—they cover it all. Plus, they share a few hilarious (and bizarre!) local news stories, touch on the generational differences in home decor, and offer practical medical insight into HRT alternatives. Key Highlights & Timestamps – Intro & Midlife Welcome Heather & Dr. Carol Lynn discuss thriving in midlife: marriage, grown kids, health, and navigating menopause together. – The Dining Table Dilemma Heather's recent move from Memphis back to Mississippi, dealing with damaged furniture, and whether to DIY repair a scratched tabletop or ship it back. – Decluttering Generations of Pictures & Keepsakes Why our kids don't want giant, ornate framed portraits of distant relatives, dealing with old family photo albums, and converting vintage film into coffee table books. Do Our Adult Children Care About Sentimentality? Generational differences in keeping family heirlooms and why younger generations view photos and keepsakes completely differently. The Estrogen Patch Shortage & HRT Alternatives Addressing the real-world shortage of estrogen patches. Where to find them: Amazon Pharmacy and select grocery chains (like Kroger) may still have stock compared to major retail pharmacies. Alternatives: Dr. Carol Lynn explains switching to once-a-week patches or oral estrogen/progesterone options during supply chain issues. Creative Birthday Ideas & Unbelievable Local News Fun birthday surprises and wild stories, including a viral clown story, unbelievable local business drama, and funny family parenting memories. Key Takeaways & Quick Advice Medical Advice Note: Always consult your own healthcare provider before making changes to your hormone replacement therapy (HRT) routine. Estrogen Patch Shortage Hacks: If your pharmacy is out of twice-weekly estrogen patches, ask your doctor about switching to a once-a-week patch or transitioning temporarily to oral estrogen. Check smaller local distributors or mail-order pharmacies like Amazon Pharmacy, which often pull from different stock networks than big-box retail drugstores. Photo & Storage Solutions: Instead of storing heavy, framed family portraits in closets or garages, consider scanning older photos into high-resolution digital files and printing a single, compact coffee table book. Connect & Share Enjoyed this episode? Subscribe to the Life Coach BFF Show on your favorite podcast app! Share the love: Leave us a 5-star review and send this episode to a friend who needs a laugh (or an estrogen patch update) today. Reminder: Don't forget to smile—Jesus loves you! Connect With Us: If you loved this episode, please hit the follow button and leave us a quick review! It truly helps other women find our community. Connect with Your Life Coach BFFs: Join the Midlife Moxie Newsletter: Don't miss out on fun items, exclusive updates, and the best life ever! The link is right in the show notes. Sign Up and Get the latest MOXIE news! Follow on Social Media: All our community connection is on our Our Midlife Moxie Facebook Page! (Yes, the podcast is Life Coach BFF Show, but our social is under Our Midlife Moxie – we hope to see you there!). @ourmidlifemoxie The Journal: Grab your My Midlife Moxie Journal on Amazon and register it on page two. Digital Version My Midlife Moxie Journal Connect with us: Sign Up and Get the latest MOXIE news! Join The Facebook Group: @ourmidlifemoxie Connect with Host Heather Pettey: Email: hpetteyoffice@gmail.com Private Coaching with Heather:https://www.ourmidlifemoxie.com/heatherpetteycoaching Speaker Request Here Instagram @HeatherPettey_ Facebook: @HeatherPettey1 Linkedin: @HeatherPettey Book: "Keep It Simple, Sarah" (Amazon bestseller) Connect with Host Dr. Carol Lynn: Linkedin Website: https://www.drcarollynn.com Facebook Group: @ourmidlifemoxie Website: www.ourmidlifemoxie.com Don't forget to subscribe to the Life Coach BFF Show for more inspiring content and practical life advice! Disclaimer: This podcast is for informational and educational purposes only. Heather Pettey is a certified coach and Dr. Carol Lynn is a licensed physician. Nothing heard on this podcast should be taken as personal medical advice. Always consult your personal physician regarding your specific health and wellness needs.
An elevated estrone level can be alarming—especially when you search online and immediately find scary information about cancer, diabetes, or obesity. But does a high estrone level automatically mean something is wrong? In this episode, Dr. Brendan McCarthy, Chief Medical Officer of Protea Medical Center, takes a closer look at estrone and why it shouldn't be treated as a simple “good” or “bad” hormone. Dr. McCarthy also discusses his own evolution in understanding estrone and why he believes good medicine requires continually questioning what we think we know. The goal isn't to tell you what decision to make. It's to give you better information so you can have a more informed conversation with your healthcare provider.
Unbreakable: A Woman's Guide to Aging with Power A clear, science-backed roadmap to building strength, supporting your body, and taking control of how you age. Get your copy: https://www.theunbreakablelifestyle.com/unbreakable-book There's a heat you can't feel until it's already aging you. Let's talk about something quietly ticking away inside all of us. In this solo episode I'm getting into inflammaging, the second great time bomb of aging, and what happens when your body's emergency crew never clocks out. Think alarm bells ringing around the clock, sirens that never quiet down. And here's where it gets personal: perimenopause. That's the wake-up call, the moment declining estrogen strips away one of your most powerful anti-inflammatory shields, and suddenly the fire's raging and no one tells you why. So I'm not leaving you there. I'll walk you through the real blueprint to put those flames out: how you move, how you eat, your hormones, and how you meet your stress. Because hear me on this one. Longevity doesn't just happen to you. You build it. On purpose. By design. What we cover: - Chronic inflammation vs. acute inflammation: what your body actually needs. - Estrogen decline in perimenopause: losing your anti-inflammatory shield. - Inflammaging effects: joints, heart, brain, and metabolism. - Physical activity and myokines: your systemic fire extinguisher. - Gut microbiome diversity: fueling or fighting inflammation. - Processed sugars and inflammation: what to eat instead. - Hormone optimization: working with a clinician to calm inflammation. - Mindfulness, breathwork, and sleep: lowering inflammatory cytokines.
What if everything you've been told about menopause is incomplete? Many women believe menopause automatically means weight gain, brain fog, fatigue, poor sleep, and feeling like the best years are behind them. But according to physician and hormone expert Dr. Miranda Naylor, menopause isn't the beginning of decline—it can become one of the greatest opportunities to reset your health. In this episode, we explore the biggest myths surrounding perimenopause and menopause, the role genetics really play, how lifestyle impacts ovarian aging, and where hormone replacement therapy fits into a personalized longevity plan. Whether you're approaching menopause, currently navigating it, or simply want to prepare for healthy aging, this conversation will leave you feeling informed, empowered, and hopeful. In this episode you'll learn: Why menopause doesn't have to mean decline Why your mother's experience doesn't determine yours The difference between chronological age, biological age and ovarian age Lifestyle habits that can dramatically improve your menopausal transition When hormone replacement therapy may be appropriate Bioidentical hormones vs synthetic hormones The importance of estrogen, progesterone and testosterone How community, sleep and stress influence hormone health Why menopause can become a powerful opportunity for reinvention Time Stamps 00:00 Welcome + Why Menopause Needs a New Narrative 02:05 The Biggest Myths About Menopause 04:45 The Unexpected Gifts of Midlife 08:30 Why Menopause Can Be Your Health Reset 10:50 Hormone Replacement Therapy: What Women Need to Know 15:15 Estrogen, Progesterone & Testosterone Explained 18:45 A Real-Life Patient Success Story 20:30 The Lifestyle Habits That Matter Most 25:05 Genetics vs. Lifestyle: Does Your Mom's Menopause Predict Yours? 27:30 Biological Age vs. Ovarian Age 31:30 HRT Myths, Breast Cancer & Safety 35:20 Dr. Miranda's RISE Method + Final Takeaways 37:10 Free Hormone Quiz + Closing Thoughts Connect with Dr. Miranda Naylor Website Instagram Modern Women's Wellness Podcast Free Hormone Quiz Connect with Us Follow & Connect: Instagram: https://www.instagram.com/theartofliving_well/ YouTube: https://www.youtube.com/@theartoflivingwellpodcast LinkedIn: https://www.linkedin.com/company/the-art-of-living-well-podcast/ TikTok: https://www.tiktok.com/@theartoflivingwel/ Spotify: https://open.spotify.com/show/4gym3jOPdSHwrpM1BmxyJz Apple Podcasts: https://podcasts.apple.com/us/podcast/the-art-of-living-well-podcast/id1482050468 Connect with your Hosts: https://www.theartoflivingwell.us/about-us
What if your hormones aren't working against you—but actually trying to tell you something?In this episode of The Women On Top, Dr. Alicia Newsome breaks down women's hormonal health in a way that's practical, empowering, and easy to understand.We talk about menstrual cycle phases, estrogen and progesterone, stress and cortisol, hormone testing, supplements, exercise, fertility after 35, and why understanding your body can change the way you feel and function.But this conversation goes beyond hormones. We also explore self-worth, purpose, and what it means to create a life—and legacy—that feels aligned.*In this episode:** Understanding your cycle and hormonal shifts* How stress impacts hormones* Estrogen, progesterone, and mood* Cycle tracking and hormone testing* Supporting hormonal health through lifestyle* Fertility after 35* Self-worth, purpose, and women's empowermentChapters:00:00 Introduction to Women's Hormonal Health01:18 Advice to My 25-Year-Old Self03:48 Understanding Menstrual Cycle Phases06:32 Hormones During Ovulation and Their Effects07:30 The Luteal Phase and Progesterone09:27 Stress, Cortisol, and Hormonal Imbalance12:40 Environmental Toxins and Estrogen Dominance15:05 Cycle Mapping and Hormone Testing20:36 Supporting Hormonal Balance with Supplements22:55 Exercise and Movement Throughout the Cycle24:57 Supporting Fertility After 3540:00 The Power of Self-Worth and Purpose52:12 Legacy and Women's Empowerment Connect with Dr. Alicia Newsome:Instagram: https://www.instagram.com/dr.alicianewsome/?hl=enYouTube: https://www.youtube.com/@dr.alicianewsomeFacebook: https://www.facebook.com/dralicianewsome/?ref=NONE_xav_ig_profile_page_web#Learn More:https://bodywellnessinstitute.practicebetter.io/#/61d24ac639803316f87085f8/bookings?s=6a727abdfa3255b509609085Connect with The Women On Top:Follow The Women On Top Podcast on Apple, Spotify, or anywhere you get your podcasts. Subscribe for more empowering conversations and stories!Website: https://thewomenontop.com/YouTube: https://www.youtube.com/@thewomenontop Instagram: https://www.instagram.com/thewomenontoppodcast/LinkedIn: https://www.linkedin.com/in/valerie-lynn/
Hormones can have a profound impact on mental health, influencing everything from mood, anxiety, and sleep to depression, agitation, and more severe psychiatric symptoms.In this episode, Dr. Alice Lee and Emily explore the hidden connection between hormone imbalance and mental health from a holistic psychiatry perspective. They discuss how estrogen, progesterone, testosterone, cortisol, neurotransmitters, inflammation, gut health, liver function, and detoxification pathways may all interact and affect emotional and psychological well-being.Emily also shares her personal journey with endometriosis, chronic pain, inflammation, psychiatric medication withdrawal, and the process of understanding how hormonal health can influence both physical and mental symptoms.Topics discussed in this episode include:• How hormone imbalance may affect mental health• The relationship between hormones and neurotransmitters• Estrogen, progesterone, testosterone, and mood• Hormonal changes and anxiety, depression, mania, and psychosis• Endometriosis, chronic inflammation, and mental well-being• Gut health, liver function, and hormone metabolism• The connection between stress, trauma, and hormonal regulation• Endocrine disruptors and everyday environmental exposures• Diet, inflammation, and holistic approaches to health• Looking for underlying causes instead of focusing only on symptomsDr. Lee also shares clinical observations that led her to look more closely at hormonal health in patients experiencing significant changes in psychiatric symptoms.This conversation highlights an important idea: mental health does not exist separately from the rest of the body. Hormones, the nervous system, immune function, inflammation, gut health, and physical wellbeing can all be deeply interconnected.Whether you are dealing with hormone imbalance, anxiety, depression, endometriosis, chronic inflammation, or simply want to better understand the relationship between hormones and the brain, this episode offers a thought provoking holistic perspective.Learn more about Dr. Alice Lee and explore additional holistic psychiatry articles, podcasts, and resources at holisticpsychiatrist.com.If you enjoyed this episode, please follow the podcast, leave a five-star rating, and share it with someone who may find this conversation helpful. Thank you for your support! I really appreciate it.Support the showTo sustain my work as a holistic psychiatrist and support my efforts to improve psychiatric treatment for all through my podcasts, articles, website, and YouTube channel, please show your appreciation and help champion holistic psychiatry by clicking HERE to contribute!Click here to listen to all of The Holistic Psychiatrist Podcast episodesContact here to email Dr. Lee directly. New! Join me on Substack A space for my opinions and reflections on cultural, political, social, and psychological issues. Feel free to comment and respond to those articles.If you like this podcast, please give it a 5-star rating and share this with others! Thank you!For more about Dr. Alice W. Lee, please visit:Website: www.holisticpsychiatrist.comMore stories and insights: Holistic ArticlesYouTube: The Holistic PsychiatristTo schedule consultations or appointments, call Dr. Lee's office at 240-437-7600Dr. Lee is located near downtown Stamford, Conn...
If you want a healthy future into old age, you need a healthy liver. Fortunately, it's extremely robust and pretty low maintenance, considering how much crazy complicated stuff it does. But at least 1 in 4 Americans has liver dysfunction, which will slowly steal some of their agency of what they're able to do as they get older. I think it's worth 20 minutes of your time to learn how to love and protect your liver. Did you know one of your liver's best protectors is estrogen? Come to my website: www.healthcouragecollective.comAre you ready to give your cells their best chance to not have to stop living before they die by allowing them access to physiologic levels of hormones, but aren't sure how to even get started? Join the waitlist for my new beta program here and help me figure out how best to help wonderful women like you get the hormone care they deserve!Join the Waitlist HereCome visit me: www.healthcouragecollective.comemail me: healthcouragecollective@gmail.com
What if the anxiety, emotional sensitivity, and overwhelm you've experienced for years are actually connected to ADHD? On this episode of SHE MD, Mary Alice sits down with board-certified psychiatrist and ADHD specialist Dr. Sasha Hamdani to unpack why ADHD is so often missed or misdiagnosed in women. They discuss the emotional side of ADHD, rejection sensitive dysphoria (RSD), hormones and ADHD symptoms, ADHD during perimenopause and postpartum, medication options, and why treating ADHD is about so much more than improving focus. Dr. Hamdani also shares the science behind her new book, Too Sensitive: Rejection, Resilience, and the Science of Feeling Deeply.Subscribe to SHE MD Podcast for expert tips on PMOS, endometriosis, fertility, hormonal balance, mental health, and more. Share with friends and visit SHE MD website and Ovii for research-backed resources, holistic health strategies, and expert guidance on women's health and well-being.SponsorsSera: To learn more you can visit PreTRM.com. Talk with your provider about whether the PreTRM Test might be right for you.Momentus: If you want to try Momentous Signature Spec Creatine, head to livemomentous.com and use code SheMD or SheMDpod for up to 35% off your entire first order. Talkiatry: Head to talkiatry.com/shemd to complete the short assessment and get matched with an in-network psychiatrist in just a few minutes. Larine: Right now, Larinco is offering our listeners up to 50% off at buylarine.com/shemd. DripDrop: Right now, DripDrop is offering podcast listeners 20% off your first order. Go to dripdrop.com and use promo code SheMD. Olly: You can find OLLY Precise Probiotics with skin, stress, or metabolism support at a Walmart near you. What You'll LearnWhy ADHD can look different in women than in menWhy women with ADHD are often diagnosed with anxiety or depression insteadHow estrogen fluctuations can affect ADHD symptoms and dopamine regulationWhat happens to ADHD symptoms during PMS, pregnancy, postpartum, perimenopause, and menopauseThe difference between stimulant and non-stimulant ADHD medicationsHow medication decisions can be personalized for women and childrenWhat rejection sensitive dysphoria (RSD) is and how it can affect relationships and daily lifeWhy emotional dysregulation is an important part of the ADHD conversationWhether supplements can help with ADHD symptomsWhy you can't “give yourself” ADHD by spending too much time on your phoneDr. Hamdani's favorite ADHD sleep hackKey Timestamps00:00 Welcome Dr. Sasha Hamdani02:40 Sasha's ADHD Diagnosis & Her Journey Through Medical School07:28 Why ADHD Looks Different In Women09:07 Why So Many Women Are Misdiagnosed With Anxiety & Depression10:20 How Hormones Can Make ADHD Symptoms Worse16:43 Estrogen, Menopause & ADHD Symptoms18:50 ADHD Medication vs. HRT: What's The Difference?20:56 Finding The Right ADHD Medication23:09 Stimulants Vs. Non-Stimulants & The 80/20 Approach25:26 ADHD Medication For Children31:44 Why ADHD Medication Can Stop Working During Perimenopause32:49 The Long-Term Effects Of ADHD Medication34:11 Are Medication Holidays Helpful?36:40 Understanding Rejection Sensitive Dysphoria (RSD)40:59 How To Regulate Emotional Dysregulation41:36 Inside "Too Sensitive" & The Science Of Feeling Deeply44:52 Dating Advice For Women With RSD47:16 Do Supplements Actually Help ADHD?48:46 Can Your Phone Make ADHD Worse?50:16 The Biggest Misconceptions About ADHD51:05 Sasha's Favorite ADHD Hack For Better Sleep52:28 Final Thoughts & TakeawaysKey TakeawaysADHD is about much more than attention and focus. It can affect emotions, relationships, sleep, eating, executive function, and everyday life.Women are frequently missed because they may present primarily with inattentive symptoms rather than the stereotypical hyperactive presentation.Hormonal changes can worsen ADHD symptoms, particularly when estrogen drops during the menstrual cycle, postpartum period, and perimenopause.Anxiety and depression can coexist with ADHD, but they can also be diagnoses that obscure underlying ADHD.Rejection sensitive dysphoria describes an intense emotional or physical response to real or perceived rejection or criticism and can be particularly disruptive for people with ADHD.Finding the right ADHD treatment is highly individualized. Medication can be one tool alongside behavioral strategies and other forms of support.Dr. Hamdani emphasizes that the goal of ADHD medication isn't to make someone feel “perfect,” but to provide consistent support that allows them to function more like they do on a good day.Emotional sensitivity isn't necessarily something that needs to be eliminated. The goal can be learning to better understand and regulate it.Guest Bio: Dr. Sasha HamdaniDr. Sasha Hamdani is a board-certified psychiatrist and ADHD specialist who has both personal and professional experience with ADHD. After being diagnosed with ADHD as a child, she went on to become a physician and now specializes in treating ADHD and helping patients better understand the condition beyond traditional symptoms of inattention and hyperactivity. She is also the author of Too Sensitive: Rejection, Resilience, and the Science of Feeling Deeply, which explores the neuroscience of emotional sensitivity, rejection, hormones, and practical tools for managing intense emotions.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
If you've suddenly become more forgetful, easily overwhelmed, anxious, irritable, or feel like your brain simply isn't working the way it used to, there's a physiological reason.Perimenopause isn't just about periods, hot flashes, or fertility. It's a major neurological and metabolic transition. Estradiol and progesterone influence your brain, nervous system, neurotransmitters, sleep, mood, memory, focus, and even how you respond to stress. When those hormones become unpredictable, your brain has to adapt too.You'll learn:Why perimenopause can feel like "PMS on steroids"How fluctuating estradiol affects memory, focus, mood, and motivationWhy word-finding, brain fog, anxiety, and overwhelm can suddenly show upHow progesterone and GABA influence that feeling of calmWhy these symptoms have real physiological explanationsSix foundational areas that can support your brain and body through this transition: nutrition, exercise, sleep, stress regulation, connection, and reducing toxin exposureUnderstanding what's happening won't make every symptom disappear, but it can replace some of the confusion with context—and help you better support your body through this season.I'm also sharing details about our FREE community screening of The M Factor II: Before the Pause on August 29 in the Jacksonville area. Join us as we continue breaking the silence and creating better conversations around perimenopause.Register through the link in the show notes.I know it's not that easy, but it really is that simple.RSVP Now to secure your seat at the screening of M Factor II: Before The PauseCheck out the Facebook Event: M Factor II: Before The PauseSupport the showGet Weekly Health Tips: thrivehealthcoachllc.comJoin the Thrive Collective Facebook groupLet's Connect:@ashleythrivehealthcoach or via email: ashley@thrivehealthcoachingllc.comPodcast Produced by Virtually You!
Summary:Dr. Natalie explores how childhood trauma and cultural conditioning influence women's relationships in midlife, emphasizing the importance of self-awareness and self-compassion to foster healthier connections and personal growth.Previous episode referenced in today's podcast: https://open.spotify.com/episode/0UrV8UKGgDdedTdw50BUdM?si=HphWMDhFTpCeMN4nJTsbNgKeywordsmidlife, relationships, childhood trauma, self-awareness, self-compassion, women, emotional health, neurochemistry, estrogen, codependencyKey topicsImpact of childhood trauma on adult relationshipsNeurochemical changes during perimenopauseThe role of estrogen in emotional resiliencePatterns of codependency and caretakingThe importance of self-awareness and self-compassionCultural influences on women's self-worthStrategies for breaking unhealthy relationship cyclesThe significance of therapy and self-reflectionTakeaways:Childhood trauma creates ingrained relationship patterns that persist into midlife.Estrogen decline in perimenopause reduces stress tolerance and can exacerbate emotional challenges.Self-awareness and self-compassion are crucial for recognizing and changing harmful patterns.Many women unconsciously conflate being needed with being loved due to early life conditioning.Healing involves understanding the origins of these patterns and actively working to rewrite them. Sound bites"Unhelpful patterns from childhood still shape us.""Estrogen decline reduces stress tolerance.""Neurochemicals protect us, but they fade in midlife."Chapters00:00 Introduction to childhood friendships and midlife reflections3555:31:04 Recognizing unhelpful relationship patterns in midlife7083:17:58 The role of childhood caretaking and its influence on adult patterns10722:11:40 The neurochemical effects of estrogen decline in perimenopause14249:58:30 Resentment and relational patterns in women during midlife17833:18:40 Understanding the origins of relationship behaviors and patterns19944:25:31 The unprecedented nature of women's midlife experiences today20638:52:16 Personal stories of escaping dysfunctional family environments22083:18:59 The importance of self-awareness and self-compassion in healing23555:32:22 The neurochemical and emotional impact of estrogen decline251111:05:48 The cycle of resentment and codependency in midlife women274722:12:33 Changing relationship patterns through awareness and intentionality288611:05:58 Recognizing residual patterns and the need for self-investment309444:26:17 The blueprint of needing to be needed and its effects316666:39:38 The importance of self-awareness in relationship transformation337777:46:21 Self-compassion and understanding the origins of patterns350833:19:46 Releasing shame and embracing growth in midlife366666:39:47 Seeking therapy and support for healing and change388888:53:11 The urgency of addressing emotional and psychological health in midlife395833:19:55 Empowering women to own their midlife journey and transformationDISCLAIMER: The content in this podcast and video is not a replacement for therapy and is not clinical, medical, or mental health treatment. Dr. Natalie Marr is a Licensed Psychologist in the state of Minnesota. Her work with (https://LearnToLoveYourStory.com) (https://NatalieMarrCounseling.com), and all affiliate social media entities is educational and coaching based ONLY. She IS NOT offering therapeutic services of any kind on these mediums. If you or someone you know is having a mental health crisis or having thoughts of suicide, please use the following crisis resources (this is not an exhaustive list of available resources):National Suicide Prevention Lifeline: https://suicidepreventionlife or CALL 988 Crisis Text Line: https://www.crisistextline.org/ or Text HOME to 741741
Broadcast from KSQD, Santa Cruz on 8-06-2026: >ul> An emailer with persistent nine-month nerve damage in her right leg after a hysterectomy asks whether peptides could help. Dr. Dawn attributes the injury to lithotomy positioning during surgery, then reviews the main nerve-regeneration candidates in the FDA peptide review pipeline: BPC-157 (Body Protection Compound, strong rat data on sciatic nerve recovery with thicker myelin sheaths), intracellular sigma peptide (targets glial scar CSPGs blocking CNS regrowth), C3 peptide 156-181, GHK-Cu (copper peptide, upregulates nerve growth factor and neurotrophin-3), self-assembling hydrogel scaffolds for bridging nerve gaps, ARA-290/cibinetide (an erythropoietin fragment with early small fiber neuropathy trial data), and Semax (used internationally for stroke rehab). She adds standard functional-medicine adjuncts: alpha-lipoic acid, methylated B12, and methylfolate at high doses for six months. An emailer asks about safe features when buying an infrared sauna. Dr. Dawn covers three concerns: EMF exposure (look for shielded/grounded heaters testing under 1 milligauss at seat level, avoid unshielded Wi-Fi and Bluetooth panels); VOC off-gassing (avoid plywood, particle board, and MDF because of formaldehyde and benzene release, and avoid Western red cedar and pine because of high terpene emissions and instead choose poplar, basswood, or eucalyptus); and avoid built-in oxygen ionizers, which produce ozone as a coronal-discharge byproduct that irritates airways and generates secondary oxygenated VOCs. Dr. Dawn covers the surprisingly long list of medications that raise estrogen in middle-aged men—including nearly all antidepressants and antiepileptics, statins, NSAIDs (specifically naproxen and indomethacin but not ibuprofen), most blood pressure medications, PPIs, H2 blockers, Parkinson's drugs, antihistamines, and muscle relaxants. She recommends annual monitoring of the estrogen-to-testosterone ratio and offers rebalancing options: topical chrysin (blocks aromatization), indole-3-carbinol, calcium D-glucarate (blocks enterohepatic estrogen recirculation), soy (competitive receptor inhibition), and grape skin extract. The first mRNA-based flu vaccine was approved this week for adults 50 and over. Beyond the 27% improvement in seasonal efficacy over conventional shots, the strategic advantage is manufacturing speed. This will be critical when or if bird flu mutates to respiratory human transmission. Since mRNA vaccine can be reprogrammed from a new viral sequence in weeks versus the three-to-four-month growth cycle for conventional flu vaccines, rapid response can save lives. But mRNA vaccine side effects include more injection-site pain and fatigue - more like a tetanus shot than a traditional flu shot.. A Spanish prospective study of chemicals affected puberty in the young studied 500 girls followed from ages 7-10 and again at 14-16 used urine chemical measurements as objective exposure markers rather than food diaries. Ethylenethiourea, a metabolite of dithiocarbamate fungicides used heavily on strawberriess,was associated with earlier menarche, while a chlorpyrifos metabolite was associated with delayed menarche. this latter effect was more pronounced in overweight girls whose fat tissue concentrated the compound. Dr. Dawn recommends organic strawberries and keeping children away from fumigated fields. University of Pennsylvania School of Dental Medicine researchers developed a chewing gum from lablab beans containing the natural antiviral protein FRIL, which reduced oral HPV by up to 93% in samples from head and neck squamous cell carcinoma patients. The gum also suppressed Fusobacterium nucleatum and Porphyromonas gingivalis, oral bacteria that promote cancer recurrence. Michigan State University's Hamburger lab studying delphinium (larkspur) alkaloids joined forces with Tomáš Pluskal's Czech Academy of Sciences lab studying wolfsbane (monkshood) after meeting at a Barcelona conference. Together they mapped the biosynthetic assembly line for aconite—an alkaloid with valuable applications against malaria, pain, cancer, and agricultural pests but impossibly slow to extract from source plants—and cloned the pathway into tobacco, which grows aggressively and produces large quantities of the compound. An emailer named in the message asks about an incidentally-discovered enlarged aorta on CT. Dr. Dawn notes it officially becomes an aneurysm at 4 cm (annual monitoring) or 5 cm (six-month monitoring), with smoking cessation critical since tobacco directly weakens the aortic wall. She describes the "zipper of fire" back pain of dissection versus catastrophic rupture, and notes Medicare covers a one-time screening ultrasound for ever-smokers over 65.
Can you use HRT after breast cancer? Is vaginal estrogen safe for breast cancer survivors? Are mammograms dangerous? And is ultrasound a better option? In this episode of Confessions of a Male Gynecologist, Dr. Shawn Tassone sits down with Dr. Liz O'Riordan, former breast surgeon, breast cancer patient, author, and advocate, for a candid conversation about breast cancer, estrogen, hormone therapy, screening, survivorship, and the realities of becoming the patient after years of being the doctor. Dr. O'Riordan thought she understood breast cancer. Then she was diagnosed herself. Her experience revealed a side of cancer care that medical training often doesn't teach: the fear of diagnosis, the physical and emotional effects of treatment, the impact of medically induced menopause, sexual health concerns, and the difficult decisions patients face when balancing recurrence risk with quality of life. Dr. Tassone and Dr. O'Riordan explore one of the most controversial conversations in women's health today: estrogen and hormone replacement therapy after breast cancer. Together, they discuss why conversations about estrogen and breast cancer are often far more complicated than "estrogen causes cancer" or "HRT is safe," how age, tumor biology, treatment history, individual risk, symptoms, and personal priorities can all influence the conversation, and why informed consent matters when women are making decisions about their health. They also discuss the important distinction between systemic hormone therapy and local vaginal estrogen, particularly for breast cancer survivors struggling with vaginal dryness, painful sex, urinary symptoms, and other consequences of estrogen deprivation. The conversation expands beyond hormones into another growing problem: breast cancer misinformation online. Do mammograms cause breast cancer? Can you replace a mammogram with an ultrasound? Can a biopsy cause cancer to spread? Dr. O'Riordan addresses common fears surrounding breast cancer screening and explains why misinformation can become dangerous when it prevents women from receiving appropriate evaluation or screening. They also discuss the concerning rise of breast cancer diagnoses among younger women, what women should understand about risk and screening, and why breast health cannot be reduced to a single test or universal recommendation. Finally, they examine something that often receives far too little attention during cancer treatment: quality of life. Exercise, nutrition, sexual health, menopause symptoms, mental health, relationships, patient support, and personal autonomy all matter during survivorship. Treating cancer is important, but so is treating the woman living through it. This is a conversation about what breast cancer care looks like from both sides of the exam room and what medicine could do better when physicians truly understand the patient experience. In This Episode, You'll Learn: Can women take HRT after breast cancer? Estrogen and estrogen-receptor-positive breast cancer Why "estrogen causes breast cancer" is an oversimplification Systemic HRT versus vaginal estrogen after breast cancer Menopause symptoms caused by breast cancer treatment Vaginal dryness, painful sex, and sexual health after cancer Quality of life versus recurrence-risk conversations What doctors may misunderstand about the patient experience Dr. Liz O'Riordan's transition from breast surgeon to breast cancer patient Rising breast cancer diagnoses among younger women Mammograms versus breast ultrasounds Whether mammogram radiation causes breast cancer Misinformation surrounding breast biopsies Exercise and breast cancer survivorship Nutrition and lifestyle after breast cancer Mental health and isolation during cancer treatment Patient autonomy and informed consent How breast cancer care could better support the whole patient About Dr. Liz O'Riordan Dr Liz O'Riordan blends surgical precision with human insight to deliver powerful messages, communication that holds, and resilience through change. A consultant breast surgeon who has faced cancer three times, Liz brings a rare dual perspective on what it means to lead, support others, and stay composed in a world of constant change, burnout risk, and fragile workplace cultures. Drawing on surgical training and her own experience of losing and regaining control, she gives repeatable methods to help people stay calm under pressure, communicate clearly when it counts, and adapt to disruption without falling apart. Liz speaks globally about how to improve the quality of patient care. Her experience as a cancer surgeon and patient, combined with the voice of over 200k people in her community, enables her to show healthcare professionals what patients really need when they leave the clinic. Alongside her keynotes, Liz delivers interactive workshops where teams practise the core habits behind sustained high performance: structured communication, adaptive leadership, decision-making under pressure, and the ability to stay calm and connected when everything around them is shifting. Her sessions are known for being honest, human, and transformative, not motivational peaks, but lasting changes in how people think and behave when the pressure is real. Dr Liz is also the best-selling author of four books, including The Cancer Roadmap. She hosts her own podcast and dedicates her spare time to creating educational content for her 200k online community. She was awarded an honorary doctorate in 2025 for her contribution to public education and received the Humanitarian of the Year Award from Future Dreams in 2024 for her advocacy, communication, and leadership. Liz is also a regular voice in international broadcast and print media, known for explaining complex ideas with clarity, warmth, and candour. Connect with Dr. Liz O'Reardon: Follow Dr. Liz O'Reardon on Instagram | Instagram Subscribe to Dr. Liz O'Reardon on YouTube | YouTube Channel Complete Guide to Breast Cancer by Liz O'Reardon The Cancer Roadmap by Liz O'Reardon Episode Resources: Work with Dr. Tassone | Tassone Advanced Gynecology Please contact the clinic directly at (512) 956- 0296 with all scheduling inquiries. Purchase Dr. Tassone's Best-Selling Book | The Hormone Balance Bible Dr. Tassone's Integrative Hormonal Archetype Quiz | Discover Your Hormonal Archetype Medical Disclaimer This podcast and website represent the opinions of Dr. Shawn Tassone and his guests. The content here should not be taken as medical advice and is for informational purposes only. Because each person is so unique, please consult your health care professional for any medical questions.
Book a free keto or low-carb consultation with Robert Sikes: https://www.ketobodybuilding.com/callYour “healthy” diet could be starving your hormones and hurting fertility before you see a warning sign.In episode 907 of the Savage Perspective Podcast, host Robert Sikes talks with fertility doctor Dr. Aumatma Simmons about why infertility is not just a woman's issue. They cover male fertility, sperm and egg quality, fertility after age 35, chronic under-eating, overtraining, RED-S, stress, poor sleep, plastics, nicotine, alcohol, IVF, and TRT. Dr. Simmons explains how protein, healthy fats, sleep, and lower toxin exposure may help prepare both partners for pregnancy. This episode shows why looking fit does not mean your body is ready to conceive.Find Dr. Aumatma Simmons on Instagram: https://www.instagram.com/holisticfertilitydoctor/Get Keto Brick: https://www.ketobrick.com/Subscribe to the podcast: https://open.spotify.com/show/42cjJssghqD01bdWBxRYEg?si=1XYKmPXmR4eKw2O9gGCEuQChapters0:00 - How Dr. Aumatma Simmons Entered Fertility Medicine4:09 - Does Female Fertility Really Fall Off a Cliff at 35?6:11 - Pregnancy After 35: Risks, Myths, and Missing Context11:55 - How Paternal Health Shapes the Placenta and Baby13:25 - The Two Biggest Fertility Obstacles: Toxins and Stress15:22 - Can Stress Resilience Improve Menstrual Cycles?16:32 - How to Measure Stress With HRV and Cortisol18:52 - Why Melatonin Supplements Affect Eggs and Sperm Differently22:26 - Which Household Toxins Hurt Fertility Most?27:01 - What Causes Gestational Diabetes During Pregnancy?29:19 - Why Protein and Healthy Fat Matter During Pregnancy31:38 - Can Undereating Cause Infertility at a Normal Weight?36:51 - How Sleep, Morning Sun, and Blue Light Affect Fertility41:18 - Does Nicotine Damage Sperm and Male Fertility?43:12 - How Alcohol Affects Fertility, Estrogen, and the Gut47:18 - How Long Should You Wait Between Pregnancies?51:44 - Is There a Biological Age Cutoff for Pregnancy and IVF?56:04 - How Birth Trauma Changed Dr. Simmons' Family Plans57:24 - How the Madre Fertility App Finds Root Causes and Toxins58:30 - Does Long-Term Birth Control Affect Fertility?1:01:23 - How TRT Affects Sperm Production and Recovery1:05:20 - Why Falling Birth Rates Are Becoming a Global Crisis
Are your hormones really the problem, or is your body missing the nutrients it needs to function properly? If you've accepted painful periods, PMS, mood swings, or low energy as "normal," this conversation may completely change the way you think about hormone health. Joining me is Izzy Fischer, founder of DailyBasis, who shares the science behind cycle syncing nutrition and why women have different nutritional needs throughout the menstrual cycle. We cover the roles of estrogen and progesterone and why iron and B vitamins matter for women of all ages. You'll understand why foundational nutrition matters long before PMS symptoms become severe and how building healthy habits today can support hormonal resilience for years to come, especially in menopause. "PMS is not normal. We should not all be in pain; we should be feeling relatively good most of the time." ~ Izzy Fischer In This Episode: - Izzy's nutrition and entrepreneurship background - Nutrients that women need to optimize hormones - Estrogen and progesterone cycle explained - Core nutrients for women: Iron and vitamins - Why foundational nutrition matters from a young age - How DailyBasis supplements work for women - Testimonials and where to buy DailyBasis supplements Products & Resources Mentioned: DailyBasis Supplements for Women: Get 30% off your first month of Cycle Routine at https://dailybasislife.superfiliate.com/MYERS or use code MYERS at checkout Fresh-Pressed Olive Oil: Try a full-size $39 bottle for just $1 to cover shipping at https://getfreshwendy.com Bon Charge Red Light Face Mask: Get 15% off sitewide, plus free shipping and a 12-month warranty, with code WENDY at https://boncharge.com/ Heavy Metals Quiz: Check your toxicity score and receive a free video series on how to detox your body. Take the quiz at https://heavymetalsquiz.com About Izzy Fischer: Izzy Fischer is a second-time founder, CPG marketer, and health-focused innovator building DailyBasis, a women's health company designed to help women feel genuinely good in their bodies with a daily supplement built around the menstrual cycle. She built and exited her first company at 23 and worked in nutrition, brand, and product leadership at Tufts Human Nutrition Center, Eclipse Foods, and Clif Bar. You can learn more about her supplement line at https://www.dailybasislife.com/ Disclaimer The Myers Detox Podcast was created and hosted by Dr. Wendy Myers. This podcast is for information purposes only. Statements and views expressed on this podcast are not medical advice. This podcast, including Wendy Myers and the producers, disclaims responsibility for any possible adverse effects from using the information contained herein. The opinions of guests are their own, and this podcast does not endorse or accept responsibility for statements made by guests. This podcast does not make any representations or warranties about guests' qualifications or credibility. Individuals on this podcast may have a direct or indirect financial interest in products or services referred to herein. If you think you have a medical problem, consult a licensed physician.
This episode explores the opportunities and risks of testosterone optimization, beginning with the US military's decision to screen men over 30 for low testosterone. Dr. Mike Hart and Dr. Jonathan Schoeff discuss why symptoms such as fatigue, low libido, and difficulty changing body composition cannot be interpreted from a single lab value. They examine the importance of free testosterone, SHBG, insulin resistance, visceral fat, estradiol, DHT, fertility, and individualized dosing. The conversation also challenges common measures such as BMI and body fat percentage, emphasizing skeletal muscle mass, visceral adiposity, sustainable health goals, and the minimum effective intervention. Dr. Jonathan Schoeff is a spinal surgeon and longevity medicine practitioner whose work focuses on hormone health, metabolic optimization, body composition, and individualized health strategy. Through comprehensive laboratory testing, clinical assessment, and personalized treatment planning, he helps clients understand how hormones, insulin sensitivity, muscle mass, visceral fat, lifestyle, and long-term health goals interact. Describing his role as that of a "biological strategist," Dr. Schoeff emphasizes precision over standardized protocols and develops practical plans designed around each person's biology, priorities, and daily life. Health and Human Performance Optimization to Enhance Military Readiness — U.S. Department of War https://media.defense.gov/2026/Jul/15/2003961654/-1/-1/1/HEALTH%20AND%20HUMAN%20PERFORMANCE%20OPTIMIZATION%20TO%20ENHANCE%20MILITARY%20READINESS%20OSD004430-26%20RES%20FINAL.PDF Influence of CAG Repeat Polymorphism on the Targets of Testosterone Action — Giacomo Tirabassi et al. https://pubmed.ncbi.nlm.nih.gov/26421011/ Comparative Effects of Daily and Weekly Boron Supplementation on Plasma Steroid Hormones and Proinflammatory Cytokines — Mohammad Reza Naghii et al. https://pubmed.ncbi.nlm.nih.gov/21129941/ Women's Health Initiative — National Heart, Lung, and Blood Institute, National Institutes of Health https://www.nhlbi.nih.gov/science/womens-health-initiative-whi Surviving Sepsis Campaign Adult Guidelines — Society of Critical Care Medicine https://www.sccm.org/survivingsepsiscampaign/guidelines-and-resources/surviving-sepsis-campaign-adult-guidelines The Longevity Lab — Dr. Jonathan Schoeff and Candace Schoeff https://longevitylabwellness.com/ Jonathan Schoeff on Instagram — Dr. Jonathan Schoeff https://www.instagram.com/jonschoeff/ Jonathan Schoeff on YouTube — Dr. Jonathan Schoeff https://www.youtube.com/@drjonschoeff Show Notes 00:00 Welcome to the Hart2Heart Podcast 00:42 Military Low T Screening 04:32 Normal Ranges and Treatment 08:19 Free Testosterone and Insulin 12:35 High SHBG and Enclomiphene 15:54 hCG Fertility and Protocols 19:35 Obesity Low T Strategy 23:26 Aromatase Inhibitors and Estrogen 26:51 DHT Mood and Libido Balance 28:57 DHT Balance Risks 30:10 Minimum Effective Dose 31:55 Longevity Strategy Mindset 33:31 Clinic Cuts Alcohol Use 35:40 Goals Drive Strategy 38:06 Body Fat Targets Debate 41:54 Sustainable Leanness 45:33 Personalized Nutrition Plans 48:09 Beyond Body Fat Metrics 52:29 Rules Not Regulations 53:31 Wrap Up And Where To Find The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to cutting through the noise and uncovering the most effective strategies for optimizing health, longevity, and peak performance. This podcast dives deep into evidence-based approaches to hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise protocols, leveraging sunlight, and de-prescribing pharmaceuticals — using medications only when absolutely necessary. Beyond health science, we explore the intersection of public health and politics, exposing how policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being. Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen). If you're ready to take control of your health and performance, this podcast is for you.We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being. Connect with Dr. Mike Hart Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart
I've got so many friends right now in one of the most popular and lucrative spaces..... They're making sick money....... One friend does $2M a week in stem cell sales. Another just sold his company for $50M. Peptides. Testosterone and Estrogen replacement therapy. Why do I tell you this? In the coming few months, I'm going to make a move in this space. I've worked hard and built companies. And I want to be around for a very long time to enjoy what I have. If AI is going to replace us all and create a world of Universal Basic Income, we're going to need to be in the best health in our lives. I may as well invest in that sector so I don't have to only rely on UBI. I have another friend who sold his company at 55 and had a heart attack. One of my first mentors told me the biggest regret he had was quitting working out. He was never able to get back to it because he had let it go. Remember, Health is Wealth. You can still move and enjoy the mobility of the world if you start preparing today. Get to work. About the ReWire Podcast The ReWire Podcast with Ryan Stewman – Dive into powerful insights as Ryan Stewman, the HardCore Closer, breaks down mental barriers and shares actionable steps to rewire your thoughts. Each episode is a fast-paced journey designed to reshape your mindset, align your actions, and guide you toward becoming the best version of yourself. Join in for a daily dose of real talk that empowers you to embrace change and unlock your full potential. Learn how you can become a member of a powerful community consistently rewiring itself for success at https://www.jointheapex.com/ Rise Above
The Department of Defense made headlines when it announced plans to test testosterone levels in active military members. The debate that followed was loud, political, and almost entirely missed the point. Jenni and Daniel are not interested in the political conversation. They are interested in the clinical one, and in this episode they take a current news story and do what they do best: strip away the noise and get to what actually matters. They start with the basics. Testosterone is not simply a marker of masculinity- it is a marker of health. Vitality. Mood. Cognitive clarity. The capacity to make good decisions under pressure. Too high creates its own problems. Too low, which is far more common, particularly in high-stress, sleep-deprived environments like military service, produces depression, fatigue, irritability, and a creeping sense that something is fundamentally off. Daniel's phrase for it, borrowed from their recent conversation with Dr. Rachel Rubin, says it precisely: I don't feel like myself. But the number alone tells you almost nothing. A reading of 450 might have one man feeling like he's on top of the world and another quietly falling apart. Context matters. Individual baseline matters. And the systems surrounding that number- sleep, stress, relationships, mental health, nutrition and physical strength matter as much as the hormone itself. Testing testosterone without addressing those systems is, as Daniel puts it, throwing a pill at a very complex situation. Jenni brings women into the conversation and makes the case that hormonal testing is not a male-only issue. She shares her own experience discovering her testosterone was in the basement despite being a muscular, physically active person, and explains why estrogen, progesterone, and testosterone together form the constellation that optimizes women's physical, sexual, and mental health. She makes the point that neither testosterone nor estrogen belongs exclusively to one gender- men need estrogen, women need testosterone, and balance is individual, not categorical. Daniel ties it back to the bio-psychosocial model- the framework that Jenni and Daniel have built their entire clinical practice around. You can test the biology. But if the psychology is suffering (anxiety, depression, unprocessed trauma) and the social dimension is broken, (relationships in conflict, connection absent isolation growing), the biology will follow. Each system pulls on the others. Fix the sleep and the testosterone improves. Improve the testosterone and the irritability decreases. Decrease the irritability and the relationship gets better. The relationship getting better reduces stress. The stress reduction improves sleep. You pull one string and it moves another one. They close with the thing that surprises most people when they say it out loud: the antidote to stress is connection. Not a supplement. Not a number. Not a protocol. The ratio of connection to disconnection in your life is one of the most powerful health metrics available- and it's the one almost nobody tracks. This episode is for veterans and first responders. It's for anyone who has wondered why they don't feel like themselves. It's for women who have never been told to test their testosterone. It's for men who didn't know that low testosterone looks like depression. And it's for anyone who has been waiting for someone to say that their relationships, their sleep, their stress load, and their hormones are not separate conversations- they are one conversation, and it starts here.See omnystudio.com/listener for privacy information.
Provider directory CBT-I: https://cbti.directory/ Book: Quiet Your Mind and Get To Sleep: https://www.abct.org/books/quiet-your-mind-and-get-to-sleep-solutions-to-insomnia-for-those-with-depression-anxiety-or-chronic-pain/Sleepio web based app with virtual therapistSomryst CBTI appCBTi coach free appInsomnia coach free appYour risk of all of the chronic diseases of aging, how healthily you age, and how powerful you're able to be in your life are all affected by how well you sleep. Good sleep is a tremendous advantage to all areas of your life, but unfortunately elusive for over 50% of American adults and up to 85% of perimenopausal women. There are so many good and effective tools to try for improving sleep. And while it's great to have options, they can make sleep seem like a harder problem to solve than it is. Different problems have different solutions, and sleep is no exception. Where to focus your resources gets way easier to decide once you understand the 4 aspects of sleep and which one of them is tripping you up. Poor sleep is absolutely a solvable problem, and worth the effort to finally figure out. And you won't have to do so by randomly guessing anymore.Are you ready to give your cells their best chance to not have to stop living before they die by allowing them access to physiologic levels of hormones, but aren't sure how to even get started? Join the waitlist for my new beta program here and help me figure out how best to help wonderful women like you get the hormone care they deserve!Join the Waitlist HereCome visit me: www.healthcouragecollective.comemail me: healthcouragecollective@gmail.com
Low libido in women is often blamed on stress, aging, or relationship problems, but changes in desire may begin years before menopause and can involve hormones, medications, pain, sleep, blood flow, and the difference between spontaneous and responsive desire. Dr. Natalie Crawford sits down with board-certified urologist Dr. Kelly Casperson, author of “You Are Not Broken” and “The Menopause Moment,” to explain why women may stop wanting sex, how testosterone and estrogen affect sexual health, and what to discuss with a clinician when something feels different. They also examine birth control and SSRI side effects, hormone therapy, vaginal estrogen, and why women's sexual health deserves greater attention. IN THIS EPISODE: 00:00 Why Women Can Lose Desire Before Menopause 02:10 Can Your Hormones Change While You Still Have a Period? 03:38 Why Testosterone Matters in Women 05:41 Can Birth Control Lower Your Libido? 08:04 How Estrogen Affects Desire, Arousal, and Vaginal Health 10:02 What Does Low Libido Actually Mean? 10:56 When Low Libido Is Really Painful Sex 13:15 Spontaneous vs. Responsive Desire 15:25 Are You Having Sex Worth Desiring? 16:53 What Causes Arousal Problems in Women? 17:20 How SSRIs Can Affect Sexual Function 17:50 How Couples Can Navigate Mismatched Sex Drives 21:05 Why Perimenopause Can Make You Feel Unlike Yourself 21:24 How Sleep, Estrogen, and Progesterone Affect Desire 21:50 Testosterone's Role in the Brain, Mood, and Motivation 24:40 How Is Testosterone Prescribed to Women? 27:15 What Happens When Testosterone Is Too High? 30:30 Can Testosterone Affect More Than Libido? 32:00 Testosterone, Wound Healing, and Bone Health 33:25 Could Testosterone Support Hip-Fracture Recovery? 34:00 Can Hormone Therapy Still Help Women Over 60? 36:00 Systemic vs. Vaginal Estrogen 37:00 Why Hormone Treatment May Begin Before Menopause 39:55 Can You Get Pregnant During Perimenopause? 41:41 When Vaginal Estrogen May Help 46:12 How to Talk to Your Doctor About Hormones 48:25 Where to Find Dr. Kelly Casperson GUEST RESOURCES:Website: https://kellycaspersonmd.comInstagram: https://www.instagram.com/kellycaspersonmdPodcast: https://kellycaspersonmd.com/you-are-not-broken-podcastYou Are Not Broken: https://kellycaspersonmd.com/you-are-not-broken-bookThe Menopause Moment: https://kellycaspersonmd.com/the-menopause-moment-book AS A WOMAN WITH DR. NATALIE CRAWFORD: YouTube: https://youtube.com/playlist?list=PLveZDgg3_HZ9m7Wy3C6Vvyrj_NtEOwj_l Apple Podcasts: https://podcasts.apple.com/us/podcast/as-a-woman/id1449553339 Spotify: https://open.spotify.com/show/12IYOLH9liu60gk5D0bRPk HOST RESOURCES: Order The Fertility Formula: https://www.nataliecrawfordmd.com/book Newsletter: https://www.nataliecrawfordmd.com/newsletter Instagram: https://www.instagram.com/nataliecrawfordmd YouTube: https://www.youtube.com/@NatalieCrawfordMD Become a patient: https://www.forafertility.com Earn FREE CE/CME: https://learnatpinnacle.com/education This episode is brought to you by The Pinnacle Podcast Network. ABOUT DR. NATALIE CRAWFORD: Natalie Crawford, MD, is a double board-certified OB/GYN and reproductive endocrinologist, co-founder of Fora Fertility, and author of The Fertility Formula. She helps women understand their hormones, fertility, and reproductive health so they can make informed decisions about their bodies. Disclaimer: Natalie Crawford, MD, is a doctor, but she is not your doctor. This content is for general education and is not a substitute for individualized medical care. Learn more about your ad choices. Visit megaphone.fm/adchoices
This episode is sponsored by Alloy. Alloy - Try the original estrogen-powered M4 skincare from Alloy. Visit https://myalloy.com and use code FLIPPING50 for $20 off your first order! More exercise can backfire—especially if you're in perimenopause or postmenopause and wondering why the workouts that once worked now leave you sore, exhausted, or stuck. In this re-release of one of our most talked-about episodes from January 2026, let's freshen our minds on the science behind why recovery, not simply working harder, becomes the key to building strength after 50. Estrogen influences your muscles, connective tissue, collagen, and energy production—and why those changes require a smarter training strategy. If you've been questioning whether you're doing something wrong, this episode will remind you that your body isn't broken; it's simply asking for a different approach. More exercise can backfire, but the right strategy can help you recover better, stay stronger, and keep doing what you love for years to come. Connect with Flipping 50: Facebook Group - Flipping50 Insiders Instagram - @Flipping50TV YouTube - @Flipping50TV More Episodes - Flipping 50 The Stronger Way Other Episodes You Might Like: Previous Episode - Lasting Weight Loss After 50: Say Goodbye to Diets Next Episode - How I Choose Supplements (and recommend you do too) More Like This: Why Your Daily Workouts Are Making You Weaker After 50 What 40+ Studies Reveal About Rep-Range for Muscle, Strength, and Bone After 50 Why Muscle Growth Feels Harder in Menopause (and What Actually Works) Resources: Not sure you're doing what is best for you right now? Get a 90-Minute Ultimate Consultation with Debra. Together, you formulate the actual plan that will work for you! Use Flipping 50 Scorecard & Guide to measure what matters with an easy at-home self-assessment test you can do in minutes. If this episode made you flip your workout routine — share it!
Precision Hormone Health: Testosterone, Menopause, Muscle, Sleep, and Proactive Longevity: Endocrinologist Dr. Florence Comite details her book “Invincible: Defy Your Genetic Destiny to Live Better, Longer” and her precision-medicine approach to proactive longevity. She discusses testosterone decline beginning in the 30s in both sexes, stress-related low T (including in special forces), and testosterone's roles in energy, cognition, motivation, muscle, bone, and chronic disease risk. Comite argues genes are a “draft” and health destiny can be altered through epigenetic-like choices, individualized data, and early monitoring. For women, she emphasizes estrogen, progesterone, and testosterone in perimenopause/menopause, preferring bioidentical hormones and criticizing WHI's use of Premarin/Provera and older participants. She covers osteoporosis prevention, muscle as an “organ of longevity,” protein intake, resistance training, continuous glucose monitors for individualized diet, sleep quality tracking via wearables, and selective use of DHEA, pregnenolone, growth hormone pathways, and peptides with attention to sourcing and risk.
Dave Crosland and Scott McNally are back to answer your bodybuilding and PED questions! We break down a new study comparing trenbolone users to steroid users who don't use tren and discuss what it may tell us about the long-term health risks of running tren, including the idea of using it year-round. Then we answer your questions on combining tren and Deca, DHB vs tren, TRT, Dianabol, chest training, cardiovascular health, and much more. ⏱️ TIMESTAMPS 0:00 Should You Run Tren & Deca Together? 1:00 Welcome Back to DNS 1:40 Technical Difficulties! 3:10 New Trenbolone Health Study 9:20 Is Year-Round Tren Ever Worth It? 14:30 Fear of Coming Off Cycle & Losing Gains 19:10 Staying On During the Diet Rebound 23:25 Low Hematocrit in Endurance Athletes 26:00 Can Dianabol Replace Testosterone? 29:30 TRT While Serving in the Military 33:25 Tren + Deca: Pros & Cons 41:00 How to Bring Up a Weak Chest 55:00 Higher Dose One Compound vs Lower Doses of Many 58:20 Testosterone Propionate & Estrogen 59:40 Dave & Scott Quit the Podcast...? 1:02:45 Uncle Dave's Advice 1:14:45 Left Ventricular Hypertrophy in Bodybuilding 1:17:35 DHB vs Trenbolone 1:19:00 Credit Scores & Final Thoughts UK Blood Work Get your Labs done by Dave in the UK : https://evalbloodanalysis.com/home/ Support the Podcast Patreon — Help keep the show growing. Even $5/month makes a difference. https://www.patreon.com/thinkbigbodybuilding Sponsors TRUE NUTRITION — Custom supplements for serious lifters Use code THINK to save https://www.truenutrition.com/THINK STROM SPORTS — Performance supplements trusted by athletes UK: https://tinyurl.com/ydmbfa54 US: https://stromsportsus.com Supplement Source Canada — Top brand supplements with fast shipping http://www.supplementsource.ca Merch Official THINK BIG Merch — Train, represent, support the brand https://think-big.printify.me/products
Estrogen receptor positive breast cancer (ER+ BC) is the most frequently diagnosed subtype of BC with consequent highest mortality. For patients with ER+ BC, standard of care treatments are endocrine therapies targeting ER expression and activity or aromatase inhibitors that block synthesis of estrogens from adrenal androgens. However, it is estimated that nearly 33% of all patients with ER+ BC will relapse within 15 years, underscoring the need for additional therapeutic optionsThis episode focuses on the role of androgen receptors in breast cancer, as it takes a look at an abstract presented at ENDO 2026, titled, The Impact of Androgen Receptors on Estrogen Receptor-Positive Breast Cancer Microenvironments. Host Aaron Lohr talks with the presenter of that abstract, Dr. Dillon Boulton, PhD, Postdoctoral fellow in the lab of Dr. Jennifer Richer at the University of Colorado Anschutz Medical Campus.
Estrogen gets blamed for a lot, but is it really the villain? Debbie breaks down what estrogen actually does, why its fluctuation, not just its level, affects your pain threshold, why perimenopause is often the hardest stretch, and what postmenopause changes. Plus, the honest limits of relying on a single blood test to explain your migraines. In this episode: What estrogen actually does in the body beyond reproduction. Why perimenopause fluctuation hits pain thresholds harder than postmenopausal levels. The liver's role in clearing hormone waste, and what happens when that process breaks down. Why bloodwork has value but isn't the whole picture. Free resource mentioned: Migraine Sensitivity Scorecard - https://pages.debbiewaidlcoach.com/quiz Resources: FREE DOWNLOAD: Toxic Migraine Triggers Guide Get the complete guide showing you the hidden inflammatory triggers fueling your migraines, including toxins in your medication, environment, and everyday life. https://dwvirtualguide.com/free-guide Book a Free Migraine Breakthrough® Assessment: Let's assess your unique migraine situation and uncover what's been keeping you stuck. https://pages.debbiewaidlcoach.com/breakthroughcall-social-7269 Connect with Debbie: Facebook: https://www.facebook.com/DebbieWaidlCoach/ Instagram: https://www.instagram.com/debbiewaidl.coach/ Women's Migraine Freedom™ Facebook Group: https://www.facebook.com/groups/womensmigrainefreedom Website: https://pages.debbiewaidlcoach.com/ Email: freedom@debbiewaidl.com Disclaimer: The Migraine Freedom™ Your Way Podcast and information provided by Debbie Waidl and guests is presented solely to provide helpful information, education, and entertainment on the subjects discussed. The use of information or resources mentioned on or linked from this podcast is at the user's own risk and discretion. This podcast is not intended to diagnose or treat any medical condition. For diagnosis or treatment of any medical problem, consult your own physician. Debbie Waidl and In The Balance Health Coaching, LLC are not responsible for any medical conditions or liable for any damages or negative consequences from any treatment, action, application, or preparation to any person reading or following the information presented on this podcast. References are provided for informational purposes only and do not constitute an endorsement of any websites or other sources. Related Episodes: Episode 1: Sex Hormones and Migraines: Why the Advice Keeps Contradicting Itself https://podcasts.apple.com/us/podcast/sex-hormones-and-migraines-why-the-advice/id1727416680?i=1000778526033 Episode 7: The Hormone Hierarchy https://podcasts.apple.com/us/podcast/understanding-the-hormone-hierarchy-tackling-hormones/id1727416680?i=1000645019506 Episode 3: Progesterone, Testosterone, and the Truth About Bioidentical Hormones (next in this series)
Thank you for joining us for our 2nd Cabral HouseCall of the weekend! I'm looking forward to sharing with you some of our community's questions that have come in over the past few weeks… Michelle: Hi Dr. Cabral! Thank you for ALL that you do! During the summer I hardly use my sauna because I'm sweating most days between early morning runs (super humid here), trail maintenance, trail runs, afternoon walks, etc. I'm sure I'm missing out on other benefits of using the sauna, however? Should I still be incorporating a 20-30 minute sauna 4-5 days per week? Jackie: My husband has mcas, and has full body itch/flush triggered by temperature change, loud stimulus and is hyper sensitive to smell/light. We tried histpro and vitamin C and it made his symptoms much worse by day 3 we stopped after day 5 and it took about a week to go back to his baseline. Any thoughts as to what happened? He Wants to do 21 day detox but really struggles to keep weight on as it is staying above 9% bf is a challenge . For context eats auto immune paleo,no alcohol and strength training is light to moderate 4 days /week.for over a decade. If you had to estimate what % of the benefit that comes from a 21 day detox is attributed to the 2 day fast and reduced calories? Trish: Good morning! QQ on women's health post-menopausal. Somewhat intimate question listeners for small children. Your opinion please on using a low dosage of women's estrogen vaginal cream to help keep the vagina tissues from thinning etc.. Thank you in advance. You are an amazing human being and are so appreciated for all you do to help us with longevity and aging gracefully. Richard: Hi Dr. Cabral, my question is on the origins of AYU medicine, I hope thats ok. I have always been fascinated with our ancient history & am wondering which civilization came up with AYU medicine. Was it the Indus Valley Civilization? You mention the system is at least 6k years old but the earliest dates of the IVC I can find are around 3300BC. Its widely accepted that Sumer was the earliest civilization which started around 4000BC but that was in Mesopotamia and not modern day India. The dates don't add up. I believe you 100% I just want to know more info on this & Im wondering if this is a case of manipulating history by the archeology industry. I have listened to podcasts with Graham Hancock & many others talking about our ancient history. They reveal convincing evidence that modern archeology is intentionally covering up certain structures, incorrectly dating them & fabricating info about civilizations. When I tried researching AYU many sources claim that its pseudoscience. Would love to hear your thoughts on all this, the truth about the origins of AYU and in what language were the texts written in 6000 years ago. Thank you!! Erin: Hi! This has been happening randomly for years & no dr has solved it. I go to sleep easily but I will wake up feeling awful & it's usually around 12:30-1am. Armpits sweating, muscles crampy, heart rate is so fast, stomach looks 6 months pregnant. I will eat something, drink and once i can start burping the heart rate slows back down and i start feeling better. I have noticed it happening more when it's really hot and humid out and certain molds are high. I have also noticed it happening when I eat around 1500 calories. I am a female and macros say i should be at 2,000-2200 for my activity level. Would this difference in calories cause this? I am wanting to loose some weight and it has been impossible due to this. My gut says adrenals but why did this start happening? So frustrated Thank you for tuning into this weekend's Cabral HouseCalls and be sure to check back tomorrow for our Mindset & Motivation Monday show to get your week started off right! - - - Show Notes and Resources: StephenCabral.com/3831 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!
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When someone says, "estrogen causes cancer" or "estrogen causes blood clots," what estrogen are they talking about? In this episode, Dr. Brendan McCarthy explains one of the biggest misconceptions in hormone replacement therapy (HRT): estrogen isn't a single hormone—it's a family of hormones. Understanding the differences between estradiol, estrone, and estriol can completely change how you view your treatment, your lab work, and the conversations you have with your healthcare provider. You'll learn why the type of estrogen, how it's delivered (oral, patch, injection, pellet), and how it's monitored all matter. Dr. McCarthy also discusses why informed consent goes beyond signing paperwork—it means truly understanding the treatment you're receiving and why it was chosen for you. In this episode: What estradiol, estrone, and estriol actually do Why estrogen is a family—not a single hormone How oral estrogen differs from patches, injections, and pellets Why delivery method changes how your body metabolizes estrogen The difference between bioidentical, synthetic, and animal-derived estrogens Why lab timing and monitoring are essential for safe HRT The importance of true informed consent in hormone therapy Four questions every patient should ask before starting estrogen When someone says, "estrogen causes cancer" or "estrogen causes blood clots," what estrogen are they talking about? In this episode, Dr. Brendan McCarthy explains one of the biggest misconceptions in hormone replacement therapy (HRT): estrogen isn't a single hormone—it's a family of hormones. Understanding the differences between estradiol, estrone, and estriol can completely change how you view your treatment, your lab work, and the conversations you have with your healthcare provider. You'll learn why the type of estrogen, how it's delivered (oral, patch, injection, pellet), and how it's monitored all matter. Dr. McCarthy also discusses why informed consent goes beyond signing paperwork—it means truly understanding the treatment you're receiving and why it was chosen for you. In this episode: What estradiol, estrone, and estriol actually do Why estrogen is a family—not a single hormone How oral estrogen differs from patches, injections, and pellets Why delivery method changes how your body metabolizes estrogen The difference between bioidentical, synthetic, and animal-derived estrogens Why lab timing and monitoring are essential for safe HRT The importance of true informed consent in hormone therapy Four questions every patient should ask before starting estrogen Hormone therapy isn't one-size-fits-all. The more you understand your hormones, the more empowered you'll be to make informed decisions about your health.
If you're a woman with multiple sclerosis (MS) and you've noticed your fatigue, brain fog, or word-finding trouble getting worse in your 40s or 50s… you're not imagining it. And you're not alone in this. In this episode, I sit down with Dr. Rhonda Voskuhl, a leading MS neurologist and menopause researcher from UCLA, to talk about something the MS community rarely hears explained clearly: what menopause is actually doing to your brain, and why it can look and feel so much like an MS flare. Here's the part that surprised me most. Your MRI can come back completely clean… no new lesions… and you can still feel like your cognition is slipping. That doesn't mean nothing is happening. It means we need to look at what's happening at the cellular level, not just the lesion level. Here's what we cover
LeAnn Rimes joins Dr. Mindy for a deeply honest conversation about what perimenopause has brought to the surface in her life.She opens up about the unpredictability of her hormones, the exhaustion of trying to maintain the same pace she has carried for decades, and the difference between anxious thoughts and anxiety that lives in the body. Together, LeAnn and Dr. Mindy explore why perimenopause can make old wounds feel louder, why hormone therapy can help without solving everything, and what it looks like to slow down when your identity has always been tied to performing, producing, and pushing through.This is a conversation about hormones, but it is also about identity, capacity, anger, rest, and the question so many women begin asking in midlife: who do I want to be now?In this episode you'll learn:The difference between mental anxiety and physical “body anxiety” Why LeAnn has had to change her relationship with rest What happens when your life still demands more than your body can give The grief women may experience around motherhood, identity, and missed choices Why hormone replacement therapy is not always a simple fix How perimenopause can force women to reconsider who they have always beenMore on LeAnn RimesLeAnn Rimes is a 2x Grammy Award-winning singer, songwriter, performer, and actress whose career has spanned more than 30 years. She rose to fame as a teenager and has since built a career across music, television, writing, and live performance. In recent years, LeAnn has also spoken openly about mental health, trauma, psoriasis, anxiety, and the realities of growing up in the public eye. She currently stars in 9-1-1: Nashville and is touring in celebration of the 30th anniversary of her album Blue.Website: leannrimes.comLeAnn's Tour DatesLeAnn's Substack: @leannrimescibrianInstagram: @leannrimesSoul of EverLe CandlesFor more resources related to today's episode, visit the podcast episode page: drmindypelz.com/ep355 Connect with Dr. Mindy:Join Reset AcademyWatch the episodes on YouTubeFollow Dr. Mindy on InstagramSubscribe to Dr. Mindy's newsletterDisclaimer: This podcast is intended for educational and informational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making changes to your diet, fasting routine, or lifestyle.
Is it perimenopause or autoimmunity? The symptoms are similar, and most women don't ask. Mickey Trescott, founder of the Autoimmune Protocol movement, explains the overlap between hormonal changes and immune dysfunction in midlife.
Send me a text! I'd LOVE to hear your feedback on this episode!You've been sold the three-day cleanse, the celery juice, the tea with a coupon code. And you've probably also heard a doctor say detox is nonsense because your body already does it on its own. Both are missing the same thing: drainage.In this episode I break down — in plain language — what detoxification actually is, what drainage is, and why one has to come before the other. I walk you through the machinery: the liver, the kidneys, the bowel, the skin, the lungs, and the lymph — the system with no pump, which moves only when you do.Then I get into what changes in midlife. Liver capacity drops. Glutathione declines. Kidney filtration slows decade by decade. Motility slows, and low estrogen and low thyroid make it worse. Estrogen influences how your gallbladder empties and how thick your bile gets, which is why gallbladder issues climb for women at exactly this stage. Menopause isn't only hot flashes and broken sleep. It's a drainage story.I also cover:- Liver phase one and phase two — and the reason phase one can make you feel worse before phase two catches up- The emunctories — your organs of elimination — and the order you have to open them- Biotherapeutic drainage and UNDA: the early-1900s European lineage behind Nebel, Discry and Reuter, and how a plant tincture paired with a homeopathic metal actually targets a specific organ- MTHFR, methylation as a phase two pathway, and my own genetics — held without the internet's drama- Where drainage costs nothing, and the free daily practices I'd start with- My own experience with cysts under the arm, and how I read it- Why emotional stagnation is a terrain too, and what it means to drain the soulNothing here is medical advice. I'm giving you breadcrumbs — take them to a qualified practitioner, one trained specifically in drainage.If this one lands, share it with one person and hit follow. It genuinely helps the show get found.Support the showInstagram: https://www.instagram.com/sandyknutrition/Facebook Page: https://www.facebook.com/sandyknutritionTikTok: https://www.tiktok.com/@sandyknutritionYouTube: https://www.youtube.com/channel/UCIh48ov-SgbSUXsVeLL2qAgRumble: https://rumble.com/c/c-5461001Linkedin: https://www.linkedin.com/in/sandyknutrition/Substack: https://sandykruse.substack.com/Podcast Website: https://sandykruse.ca
Hormones or no hormones? Itchy ears. Disappearing pussy syndrome. Estrogen by land, by sea, by patch, by pill, or by cream. When is it T time? What's the deal with herbal remedies? Should your moisturizer have hormones in it? Is HRT safe? Four experts weigh in on bioidentical versus synthetic, getting better sleep, what to put in or around your vagina, tips for trans folks, protein research, and why you should go pick up a brick or something. OB/GYNs and menopause experts Dr. Monica Christmas and Dr. Mary Claire Haver – who wrote the book The New Perimenopause – are back for this Part 2 all about science-backed fixes to your menopausal probs. Joining the chat is Smith College exercise physiologist Dr. Sarah Witkowski with a cameo from anthropologist and bone expert Dr. Daniel Wescott. Again, bonus Part 3 this week will be tips for your loved ones. We're all in this together, kiddos. Start with Emmenology (MENOPAUSE) Part 1 Browse Dr. Christmas's papers on ResearchGate and follow her on Instagram Visit Dr. Haver's website and follow her on Instagram, YouTube, TikTok, and Substack Buy Dr. Haver's books, The New Menopause, The New Perimenopause, The Galveston Diet Learn more about Dr. Sarah Witkowski's work Donations went to the Center for Food Equity in Medicine and St. Jude Children's Research Hospital and the Menopause Society RosebudWoman.com (owned by my wonderful in-laws!) will give you 15% off with the code OLOGIES Tortoise Sword from Jarrett Sleeper's JB Stink brand shirts More episode sources and links Other episodes you may enjoy: Urology (CROTCH PARTS), Gynecology (NETHER HEALTH), Neuroendocrinology (SEX & GENDER), FIELD TRIP: Alie's Mystery Surgery, Surgical Angiology (VEINS & ARTERIES), Cardiology (THE HEART), Biogerontology (AGING), , Biological Anthropology (SEXY APES), Evolutionary Anthropology (METABOLISM), Thermophysiology (BODY HEAT), Somnology (SLEEP), Mnemonology (MEMORY), Attention-Deficit Neuropsychology (ADHD), Molecular Neurobiology (BRAIN CHEMICALS) 400+ Ologies episodes sorted by topic Smologies (short, classroom-safe) episodes Sponsors of Ologies Transcripts and bleeped episodes Become a patron of Ologies for as little as a buck a month OlogiesMerch.com has hats, shirts, hoodies, totes! Follow Ologies on Instagram and Bluesky Follow Alie Ward on Instagram and TikTok Editing by Mercedes Maitland of Maitland Audio Productions and Jake Chaffee Managing Director: Susan Hale Scheduling Producer: Noel Dilworth Transcripts by Aveline Malek Website by Kelly R. Dwyer Theme song by Nick Thorburn Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Erin and Alyssa get into Pete Hegseth's new testosterone policy, and the latest on the Tate Brothers arrest. Then they do a supersized Sani-Petty with producer Caroline and sprinkle a little joy into the week to celebrate Alyssa's last episode!US military to start screening for testosterone deficiency, Hegseth says (BBC 7/16)Estrogen patches are hard to find, and it may not be resolved any time soon (CNBC 6/26)Will the Tate brothers be extradited from the US to the UK? (BBC 7/20)Andrew and Tristan Tate arrested on rape, trafficking charges. What to know. (Washington Post 7/19)
Postmenopausal muscle loss is a real problem many women deal with, but it doesn't have to be. Find out how to build muscle after menopause to help you stay healthy, strong, and youthful.0:00 Menopause muscle loss1:55 Estrogen and muscle loss2:50 How to build muscle after menopause 5:00 Sarcopenia 6:19 Hormone therapy and postmenopausal muscle loss7:24 Protein for menopause 7:45 Best protein sources for muscle growth9:05 Diet tips for postmenopausal muscle loss11:02 Muscle-building tips
This week on Laugh Lines, Penn and I not only strip down due to our A/C being out... AGAIN! We also tackle two things I never expected to happen in the same podcast: Becoming an (almost) empty nester and hunting down an estrogen patch like it was contraband due to a recent shortage.We discuss my hormones going on strike, and a voicemail from a mom preparing to send her child to college inspired us to share the biggest lessons we've learned after Lola's first year away. We also revisit "Father of the Bride" through Gen Z eyes (Spoiler: George Banks was making a lot of sense), realize that 1991 was somehow 35 years ago, play a very heated game of The Price Is Right, and give a spirited tribute to the late Bonnie Tyler. Yes, Penn got out the recorder.If you're navigating hormones, parenting grown kids, or simply trying to figure out how we all got this old, come laugh with us. We promise you'll leave feeling a little less alone. We love to hear from you! Leave us a message at 323-364-3929 or write the show at podcast@theholdernessfamily.com. You can also watch our podcast on YouTube. And thanks to our partner, OLLY, for sponsoring this episode!Pre-order Get It Done & Have FunVisit Our ShopJoin Our NewsletterFind us on SubstackFollow us on InstagramFollow us on TikTokFollow us on FacebookLaugh Lines with Kim & Penn Holderness is an evolution of The Holderness Family Podcast, which began in 2018. Kim and Penn Holderness are award-winning online content creators known for their original music, song parodies, comedy sketches, and weekly podcasts. Their videos have resulted in over three billion views and over nine million followers since 2013. Penn and Kim are also authors of the New York Times Bestselling Books, ADHD Is Awesome: A Guide To (Mostly) Thriving With ADHD and All You Can Be With ADHD. They were also winners on The Amazing Race (Season 33) on CBS. Laugh Lines is hosted and executive produced by Kim Holderness and Penn Holderness, with original music by Penn Holderness. Laugh Lines is also written and produced by Ann Marie Taepke, and edited and produced by Sam Allen. It is hosted by Acast. Thanks for listening! Hosted on Acast. See acast.com/privacy for more information.
Two out of three Alzheimer's patients are women, and for decades that gap was written off as a side effect of living longer. The newer neuroscience tells a more specific story: menopause is not a reproductive event, it's a neurological one, and the pathology begins 20 to 30 years before the first symptom. In this episode, Louisa breaks down why the female brain loses its primary protection around 40, what actually drives the disease, and the seven evidence-based protections that can change the trajectory. She starts with the estrogen shield, the four things estrogen does in the female brain that nothing else replicates: it drives mitochondrial biogenesis, suppresses amyloid plaque formation, upregulates antioxidant enzymes, and maintains white matter integrity. You'll hear why estrogen doesn't decline smoothly but swings wildly through perimenopause before dropping roughly 80% by postmenopause, what PET scans already show in women in midlife, and why a 2021 paper by Mosconi and colleagues named menopause the single strongest predictor of Alzheimer's brain changes, stronger than age, stronger than family history. Then she turns to what you can do about it. You'll learn why resistance training, not cardio, produces the irisin and BDNF cascade that targets the exact pathological hallmarks of Alzheimer's, and why two sessions a week was enough to preserve the brain regions the disease hits first. She covers the glymphatic system that clears amyloid and tau only during deep sleep, and why 70 to 80% of women in perimenopause lose exactly that sleep at exactly the wrong moment. She walks through the HRT timing fork, 32% lower risk when therapy starts within five years of menopause versus 38% higher when it starts after 65, the MIND diet's 53% risk reduction, the omega-3 dose most women get wrong by a factor of five, and the cortisol crisis that runs like a thread through every mechanism in the episode. It's not a death sentence. It's a timeline, and there is a window where the right information changes the outcome. To sponsor an episode- https://open.substack.com/pub/neuroathletics/p/sponsor-tne *Reduce your risk of Alzheimer's with my science-backed protocol for women 30+:* https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ *TOPICS DISCUSSED* 00:00 Intro: Two Out of Three Alzheimer's Patients Are Women 00:37 The Estrogen Shield and the Four Things It Does in Your Brain 02:13 What Happens to the Brain When Estrogen Drops 03:01 The Reframe: Menopause Is a Neurological Event, Not a Reproductive One 03:31 Why Women Develop More Tau Than Men 04:15 The 20-Year Head Start: It Begins in Your 30s and 40s 05:02 When the Silent Window Collides With Perimenopause 05:44 The Symptoms Women Are Told to Dismiss 06:42 The Diagnostic Gap and the APOE4 Risk 08:59 Protection 1: Why Resistance Training Beats Cardio 09:31 Irisin, BDNF, and Fertilizer for Your Neurons 10:37 The Brain-Scan Proof: Two Sessions a Week 11:16 Why Chronic Cardio Can Work Against Your Brain 13:36 Protection 2: The Glymphatic System and Deep Sleep 14:53 How Your Brain Cleans Itself Overnight 15:56 The Sleep Collision That's Specific to Women 16:37 Why Deep Sleep Beats Total Hours 18:41 Protection 3: The HRT Timing Window 18:56 32% Lower vs 38% Higher: Same Therapy, Opposite Outcomes 20:56 The 2002 Data Still Driving the Wrong Advice 21:05 APOE4 Carriers and the Largest HRT Benefit 23:19 Protection 4: The MIND Diet and a 53% Lower Risk 24:20 The Omega-3 Dose Most Women Get Wrong 25:17 Berries, Anthocyanins, and the Foods to Cut 27:38 The Cortisol Crisis: The Thread Through Everything 28:58 The Estrogen and Cortisol Feedback Loop 30:18 The "Healthy" Routine That's Quietly Hurting Your Brain 31:08 Seven Layers, One Message: This Is Preventable _______ *Thank you to our sponsors* Function Health: https://functionhealth.com/LouisaNicola - Use code NEURO25 for a $25 credit Timeline (Mitopure): https://timeline.com/neuro - Use code NEURO for a discount IQBAR: Text NEURO to 64000 for 20% off all IQBAR products plus FREE shipping (Message and data rates may apply) Cozy Earth: https://cozyearth.com - Use code NEURO for 20% off _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices