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Get ready for another insightful Q&A episode featuring your questions! Curious about hormone health and its impact on your well-being? Ever wondered why testosterone cream might cause pesky side effects like acne or hair growth? We discuss potential solutions and alternatives to consider. Struggling with weight gain or stubborn weight loss during menopause? Discover how hormone fluctuations might be playing a role and what steps you can take to regain control. We also delve into the nuances of estradiol therapy post-hysterectomy and the vital importance of monitoring your hormone levels for overall health. Concerned about hormone therapy's role in Alzheimer's risk management, especially if you have the APOE4 gene? We explore personalized strategies that combine diet, exercise, and hormone adjustments. Don't miss out on understanding how accurate hormone testing can enhance your health journey! In this episode, we uncover: How to manage common testosterone cream side effects like acne and hair growth. Why weight gain during menopause might be linked to hormone fluctuations. How estradiol and progesterone creams can alleviate menopause symptoms. Why individualized hormone strategies are crucial for Alzheimer's risk management. How different hormone testing methods provide insights into your health. Unlock valuable knowledge about hormone health by checking out this episode now. Whether you're navigating menopause or curious about HRT, there's something here for everyone! Sponsors Use coupon code HORMONE for 20% off your order. Try the NEW Lemonade LMNT!! Order your LMNT electrolytes today and get a FREE 8 pack of samples! Plus try it risk free, they have a no-questions-asked refund policy – you don't even have to send it back! Timeline is offering 20% off your first order of Mitopure. Go to timeline.com/HORMONE20 and use coupon HORMONE20 and get 20% off your order. Episode Mentions Urine Metabolite Testing for Hormones & What it Tells You, Who It is for & Why It is The Gold Standard of Testing with Karen Martel & Cohost Dr. Amie Hornaman Everything You Need to Know About Hormone Testing Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada. Visit karenmartel.com to explore our comprehensive programs: Bioidentical Hormone Replacement Therapy Individualized Weight Loss Programs Peptide Therapy for weight loss Interested in our NEW Peptide Weight Loss Program? Join today and get all the details here. Join our Women's Peri and Post Menopause Group Coaching Program, OnTrack, TODAY! To our nursing audience members, our podcasts qualify for nursing CE @ RNegade.pro. Provide # CEP17654. Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert Karen's Facebook Karen's Instagram
Ian Kerner, nationally recognized sex therapist and author, joins Dr. Rena Malik to discuss the essentials of a fulfilling sex life, including communication, sexual scripts, psychological arousal, and the importance of both novelty and familiarity in intimate relationships. The conversation covers strategies for reigniting desire and maintaining the spark in long-term partnerships, practical tips for pleasuring partners, overcoming sexual shame and avoidance, using fantasy and psychological stimulation, and introducing topics like pornography or non-monogamy. Become a Member to Receive Exclusive Content: renamalik.supercast.com Schedule an appointment with me: https://www.renamalikmd.com/appointments ▶️Chapters: 00:00:00 Introduction00:00:51 Menopause Definitions00:02:54 Estrogen and Skin00:07:05 Estrogen and Brain Health00:11:11 Estrogen and Weight Gain00:12:54 Bone Health and Osteoporosis00:18:53 Joint Health and Pain00:24:30 Mood and Depression00:28:28 Cardiovascular Health00:32:36 Vasomotor Symptoms00:36:04 Pelvic Floor, Vaginal, and Urinary Changes Stay connected with Dr. Ian Kerner on social media for daily insights and updates. Don't miss out—follow him now and check out these links! INSTAGRAM - https://www.instagram.com/iankernerlmft/ https://amzn.to/44btgKo Let's Connect!: WEBSITE: http://www.renamalikmd.com YOUTUBE: https://www.youtube.com/@RenaMalikMD INSTAGRAM: http://www.instagram.com/RenaMalikMD TWITTER: http://twitter.com/RenaMalikMD FACEBOOK: https://www.facebook.com/RenaMalikMD/ LINKEDIN: https://www.linkedin.com/in/renadmalik PINTEREST: https://www.pinterest.com/renamalikmd/ TIKTOK: https://www.tiktok.com/RenaMalikMD ------------------------------------------------------ DISCLAIMER: This podcast is purely educational and does not constitute medical advice. The content of this podcast is my personal opinion, and not that of my employer(s). Use of this information is at your own risk. Rena Malik, M.D. will not assume any liability for any direct or indirect losses or damages that may result from the use of information contained in this podcast including but not limited to economic loss, injury, illness or death. Learn more about your ad choices. Visit megaphone.fm/adchoices
Your everyday habits might be accelerating aging, and this episode reveals what to do instead. You'll learn how specific plants trigger powerful longevity pathways and how to eliminate the hidden toxins disrupting your hormones, brain, mitochondria, and overall health. This is a masterclass in biohacking from two experts who've spent decades researching how to upgrade the human body. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey is joined by Darin Olien, environmental health expert, bestselling author of Fatal Conveniences, and co-host of the Netflix series Down to Earth with Zac Efron. Darin has traveled the globe uncovering forgotten plant compounds, investigated the most overlooked environmental toxins, and now works with leading scientists and governments to bring these breakthroughs into functional medicine and human performance. Together, they break down: • How rare plant compounds like osmotin support adiponectin and mitochondrial repair • Why PFAS, synthetic fragrances, and EMFs are sabotaging your biology • How environmental toxins contribute to hormone disruption and infertility • What makes tap water so dangerous and how to fix it with simple filtration • Why microplastics and heavy metals are harder to avoid than ever • The role of habit design, detox protocols, and indoor air quality in biohacking longevity • Why removing toxins first leads to better results in fasting, ketosis, nootropics, and cold therapy This episode delivers practical tools for building resilience, improving detox capacity, and navigating the modern world with awareness. You'll also get insights into the systems that have failed to protect public health and how personal action can create collective change. If you're interested in senolytics, sleep optimization, neurohacking, and smarter ways to upgrade your environment, you'll find those topics explored in depth throughout this channel. Whether you're detoxing from hidden toxins or optimizing with Danger Coffee, this conversation aligns with the core principles of Smarter Not Harder and the mission of Upgrade Labs. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. SPONSORS: -OneSkin | Get 15% off your first purchase at https://oneskin.co/ASPREY with code ASPREY. -Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. -Apollo Neuro | To get an Apollo wearable, go to https://apolloneuro.com/Dave and save 15%. Resources: • Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Darin's Website – https://superlife.com/ • Darin's Instagram: https://www.instagram.com/darinolien/ • Danger Coffee: https://dangercoffee.com • Dave Asprey's Website: https://daveasprey.com • Dave Asprey's Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:10 Intro • 02:14 Meet Darin Olien • 04:26 Wildfires and Pollution • 07:13 PFAS and Everyday Toxins • 12:37 Corporate and Regulatory Failure • 26:36 Synthetic Fragrances • 36:12 Water and Air Filtration • 36:53 Indoor Air Quality • 38:33 Building Healthy Habits • 40:05 Essential Oils and Hormones • 41:54 Tofu, Tempeh, and Estrogen • 46:34 Adiponectin and Biohacking • 47:04 Osmotin for Longevity • 49:48 Stem Cells and Repair • 53:57 Communicating Science • 01:04:12 Nutrition and the Microbiome • 01:06:14 Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
This week is like Christmas in June for me. I get to talk more about perimenopause--ya know how much I like to talk about that! The conversation covers the power of the big bad bit$h Estrogen and so much more about wellness for women. My guest this week is Lisa Rigau MS, BSN, RN, DipACLMHealth & Wellness Nutritionist and Certified Teacher of Mindfulness Based Stress Reduction, Healthy Lifestyle Management. Lisa tells us why a plant-based diet is healthy, how foods can affect our perimenopause symptoms like poor sleep and sweating, how to incorporate mindfulness into our lives and so much more to empower us to make choices that improve our health. Sign up for Lisa's newsletter, learn more about her services and contact her at her website: www.EatBreatheMoveLive.com Thank you to my podcast sponsor Reinvented Threads with Gabby Lynn. Gabby is creative, kind and makes beautiful eco-friendly fashion accessories including purses, hats and more. Visit her online store and learn where she'll be in the Lehigh Valley by clicking here. If you would like to support the content featured on Uncorked with Funny Wine Girl and help women continue to have a platform to inspire, inform and entertain, please reach out to Jeannine at Jeannine.Luby@gmail.com. Monthly podcast sponsorship packages are more affordable than buying a coffee a day outside the home. Remember that you can also show support by sharing the podcast on your social media and/or telling a friend, foe or anyone you know! Follow Funny Wine Girl Jeannine on Instagram and Facebook. I appreciate you from the bottom of my heart and the bottom of my wine glass.
In this episode, Dr. Shawn Tassone examines a paradigm-shifting study from the Journal of the North American Menopause Society that demolishes decades of unfounded hysteria surrounding hormone replacement therapy for women over 65. The research reveals that HRT—specifically estrogen therapy—administered beyond age 65 correlates with significant risk reductions across multiple disease categories: mortality, breast cancer, lung cancer, colorectal cancer, congestive heart failure, venous thromboembolism, atrial fibrillation, myocardial infarction, and dementia. The findings underscore the critical importance of precision medicine approaches utilizing individualized protocols, lower dosing strategies, and non-oral delivery methods for optimal clinical outcomes. Episode Highlights The NAMS study that's rewriting the hormone therapy playbook for women over 65 Quantifiable risk reductions across nine major disease categories, including the holy grail of mortality reduction Why the data on breast cancer, lung cancer, and colorectal cancer risk reduction should make us question everything we thought we knew The cardiovascular benefits that contradict decades of clinical paranoia: reduced congestive heart failure, venous thromboembolism, atrial fibrillation, and heart attacks Dementia risk reduction—because apparently estrogen is neuroprotective, not neurotoxic The vindication of individualized hormone therapy protocols using lower doses and transdermal delivery Estrogen monotherapy combined with progesterone: the life-extending intervention hiding in plain sight How this research obliterates the arbitrary age-based cutoffs that have dominated clinical practice Why your patients over 65 deserve a risk-benefit analysis based on actual science, not medical mythology The clinical implications for practitioners ready to abandon fear-based prescribing in favor of evidence-based care Episode Resources Dr. Shawn Tassone's Practice | https://www.drshawntassone.com Dr. Shawn Tassone's Book | The Hormone Balance Bible Dr. Shawn Tassone's Integrative Hormonal Mapping System | Hormone Archetype Quiz Thank you to our sponsor, Purality Health! The question isn't which supplements to take—it's whether your body can absorb them. Most traditional supplements fall victim to stomach acid before delivering benefits. Purality Health's micelle liposomal technology creates a double-layer protective system that shields nutrients from stomach acid destruction while facilitating direct bloodstream absorption—making supplements up to 800% more effective. For perimenopausal and menopausal patients, I recommend their Vitamin D3 with K2 for bone density and mood regulation, and their exceptional magnesium formula for sleep and muscle tension. As a physician, I value their commitment to quality: cGMP-compliant facilities, purity testing, and organic, non-GMO ingredients without unnecessary fillers. Visit puralityhealth.com/drshawn and use code DRSHAWN for exclusive savings. Medical Disclaimer This podcast and website represent the opinions of Dr. Shawn Tassone and his guests. The content here should not be taken as medical advice and is for informational purposes only. Because each person is so unique, please consult your health care professional for any medical questions.
I'd like to say thanks to Anna Magpie – who offers literature review as a service – for her help reviewing the section on neuroendocrinology. The following post discusses my personal experience of the phenomenology of feminising hormone therapy. It will also touch upon my own experience of gender dysphoria. I wish to be clear that I do not believe that someone should have to demonstrate that they experience gender dysphoria – however one might even define that – as a prerequisite for taking hormones. At smoothbrains.net, we hold as self-evident the right to put whatever one likes inside one's body; and this of course includes hormones, be they androgens, estrogens, or exotic xenohormones as yet uninvented. I have gender dysphoria. I find labels overly reifying; I feel reluctant to call myself transgender, per se: when prompted to state my gender identity or preferred pronouns, I fold my hands [...] ---Outline:(03:56) What does estrogen do?(12:34) What does estrogen feel like?(13:38) Gustatory perception(14:41) Olfactory perception(15:24) Somatic perception(16:41) Visual perception(18:13) Motor output(19:48) Emotional modulation(21:24) Attentional modulation(23:30) How does estrogen work?(24:27) Estrogen is like the opposite of ketamine(29:33) Estrogen is like being on a mild dose of psychedelics all the time(32:10) Estrogen loosens the bodymind(33:40) Estrogen downregulates autistic sensory sensitivity issues(37:32) Estrogen can produce a psychological shift from autistic to schizotypal(45:02) Commentary(47:57) Phenomenology of gender dysphoria(50:23) References--- First published: June 15th, 2025 Source: https://www.lesswrong.com/posts/mDMnyqt52CrFskXLc/estrogen-a-trip-report --- Narrated by TYPE III AUDIO. ---Images from the article:
Dr. Jessica Shepherd returns to the WHOOP Podcast for this month's episode of the How To Series. Dr. Shepherd joins WHOOP Global Head of Human Performance, Principal Scientist, Dr. Kristen Holmes to redefine menopause. Dr. Jessica Shepherd is an OBGYN, menopause expert, and author of Generation M, guiding women through the various stages and lifestyle changes that come with menopause and peri-menopause. Dr. Holmes and Dr. Shepherd bring attention to the symptoms to look out for, create an understanding of the power of early preparation, and establish the importance of strength training and protein intake to support hormonal health. This episode brings to light the need for advocacy in the health space for menopause and peri-menopause care.(00:37) Introducing Dr. Jessica Shepherd(01:14) Reframing Menopause: Dr. Shepherd Personal Mission(03:22) Recognizing The Signs: Symptoms of Perimenopause & Menopause(04:10) Staying Ahead of Symptoms(06:55) What Women in Their 30s Should Know(09:26) Protein & Power: Building Strength for Hormonal Health(12:14) The Positive Role of Daily Activity(15:11) Menopause As A Metabolic Disease(19:12) Lifestyle Changes To Promote Metabolic Health(23:10) Important Biomarkers for Hormonal Health(29:44) Dr. Shepherd's Toolkit For Women with Perimenopause(33:11) Estrogen Creams: Benefits and Practices(36:01) Understanding Hormone Replacement Therapy(39:27) Estrogen's Effects on Cognitive Health, Sleep, & Longevity(42:14) When To Start Taking Estrogen(45:27) The Healthy Choices That Ease Menopause Symptoms(47:57) Birth Control & Peri-Menopause: Detecting Symptoms(51:15) Advocacy for Peri-Menopause and Menopause Care(55:15): Centering Dialogue Around Menopause(01:00:35): The Future of Research in Women's Health(01:05:52): WHOOP as a Tool for Support(01:10:10) Exercise Options to Improve Overall Health(01:11:37) Dr. Shepherd's Closing MessageDr. Jessica Shepherd:WebsiteInstagram LinkedInChanging the Conversation Around Menopause with Dr. Jessica ShepherdSpotifyApple PodcastsYoutubeSupport the showFollow WHOOP: www.whoop.com Trial WHOOP for Free Instagram TikTok YouTube X Facebook LinkedIn Follow Will Ahmed: Instagram X LinkedIn Follow Kristen Holmes: Instagram LinkedIn Follow Emily Capodilupo: LinkedIn
In this episode, Tara breaks down what estrogen metabolites are, why they matter, and whether it's necessary to invest in expensive hormone tests. She explains how the body metabolizes estrogen through the liver and gut, and which lifestyle and nutrition strategies support this process - regardless of what your test results may say. Tara also discusses the limitations of supplements like DIM and calcium D-glucarate, urging listeners to focus on diet, gut health, and personalized nutrient support instead of chasing quick fixes. You'll learn: What estrogen metabolites are (2-OH, 4-OH, 16-OH -yes, we decode the jargon!) Why a healthy liver and gut are critical for hormone detox The truth about DIM and calcium D-glucarate (and why they might not be right for everyone) The difference between true root-cause healing vs. supplement band-aids The practical, proven strategies Tara recommends instead of jumping into expensive testing Mentioned in this episode: MegaSporeBiotic – Click HERE to grab this probiotic and use my practitioner code, which also gets you 10% off: TaraMegaSpore Paleovalley – Grab your goodies as mentioned in this episode, HERE Blue Light Blocking Glasses Recommendations: Baxter Blue (Australian site) Save 15% when you use Tara's code: Tara15 Bon Charge Save 15% when you use Tara's code: TARA15 HRT Made Simple™ - Learn how to confidently speak to your doctor about the benefits of hormone replacement therapy so you can set yourself up for symptom-free, unmedicated years to come without feeling confused, dismissed, or leaving the medical office minus your HRT script. Hair Loss Solutions Made Simple™ – This course will teach you the best natural, highly effective, and safe solutions for your hair loss so you can stop it, reverse it, and regrow healthy hair without turning to medications. The Hormone Balance Solution™ – My signature 6-month comprehensive hormonal health program for women in midlife who want to get solid answers to their hormonal health issues once and for all so they can kick the weight gain, moodiness, gut problems, skin issues, period problems, fatigue, overwhelm, insomnia, hair/eyebrow loss, and other symptoms in order to get back to the woman they once were. [FREE] The Ultimate Midlife Perimenopause Handbook - Grab my free guide and RECLAIM your confidence, your mood, your waistline and energy without turning to medications or restrictive diets (or spending a fortune on testing you don't need!). [BOOK A 30-MINUTE SESSION WITH TARA HERE]
Estrogen often gets a bad rap, but it's one of the most powerful and protective hormones in a woman's body, especially in midlife. In this episode of Perimenopause Simplified, we're unpacking what estrogen does, how it changes after 40, and what you need to know about supporting it through perimenopause and beyond. Whether you're dealing with brain fog, vaginal dryness, or mood swings, this episode will help you understand whether low estrogen might be at play – and what you can do about it. We also dive into hormone replacement therapy (HRT), the different forms of estrogen available, and why progesterone is essential if you choose to supplement. Estrogen isn't the enemy; let's set the record straight. What's covered in this episode: The benefits of estrogen for your brain, heart, bones, and mood How estrogen levels fluctuate and decline during perimenopause and menopause Signs and symptoms of low estrogen vs. estrogen excess When to consider estrogen HRT and the different types (patches, gels, Biest & more) Why progesterone is needed when taking estrogen HRT How to support healthy estrogen detoxification through liver, gut, and lifestyle strategies Link Mentioned: Ep. 31: How Endocrine Disruptors Impact Perimenopause For a deeper dive into estrogen, listen to Ep. 36: Estrogen: Why We Love It & Need It w/ Jill Chmielewski, RN, BSN
Dr. Natalie Crawford, double board certified OBGYN and REI, breaks down the complex world of reproductive hormones, providing you with a comprehensive guide to understanding their menstrual cycle, hormone function, and reproductive health. Key Topics Covered: 1. Hormone Basics -The HPO (Hypothalamus-Pituitary-Ovary) Axis -How hormones communicate in the body -Roles of key hormones: GnRH, FSH, LH, Estrogen, Progesterone 2. The Menstrual Cycle Explained -Egg development and ovulation process -Hormone fluctuations throughout the cycle -Normal cycle length and characteristics 3. Hormone Health Insights -Identifying normal vs. abnormal cycles -Impact of prolactin and thyroid hormones -Importance of hormone testing 4. Common Misconceptions -Estrogen dominance -Hormone balance -Effects of biotin on hormone testing Want to receive my weekly newsletter? Sign up at nataliecrawfordmd.com/newsletter to receive updates, Q&A, special content and freebies If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every Tuesday. Plus, be sure to follow along on Instagram @nataliecrawfordmd, check out Natalie's YouTube channel Natalie Crawford MD, and if you're interested in becoming a patient, check out Fora Fertility. Join the Learn at Pinnacle app to earn FREE CE Credit for listening to this episode! This episode is brought to you by The Pinnacle Podcast Network! Learn more about Pinnacle at learnatpinnacle.com Learn more about your ad choices. Visit megaphone.fm/adchoices
Welcome to Quick Hits: Blasts from The Past. Join Karen as she explores her podcast archives, offering you short, impactful excerpts from standout episodes. In just 15 minutes, you'll experience the essence of past conversations, packed with valuable insights and memorable moments from our guests. If you want to dive deeper, you'll find links to the full episodes in the show notes below. Listen to the full episode. Julie Donaldson is a clinical nutritionist practicing metabolic nutrition, functional health testing and health care, bodywork and mind/body relationships. She works with all types of health conditions and dysfunction, as she sees that there are a set of core root causes of all illnesses with an infinite array of individual expressions. In this episode, we're diving into a fascinating topic: estrogen toxicity and how to support safe detoxification. We'll explore the difference between estrogen dominance and toxicity, and the symptoms of both. Julie shares her experience using testing methods like Dutch testing. We'll take a closer look at phases 1 and 2 estrogen detoxification process and how it affects our body's levels of estrogen. We clarify that estrogen, specifically estradiol, is not the problem, but rather estrogen-mimicking compounds. We'll discuss how compounds like phenolics and heavy metals can act on our hormone receptors and potentially contribute to weight gain and gut issues like SIBO. But don't worry, we've got you covered with safe ways to support proper detoxification, like the importance of bile, coffee enemas, and the pros and cons of detox supplements like DIM. Overall, this episode offers a comprehensive look at estrogen toxicity and provides practical solutions for safely supporting proper detoxification. Visit True Nature Health Consulting. Sponsors Get 15% off your Primeadine purchase with coupon code KM15 here. Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada. Visit karenmartel.com to explore our comprehensive programs: Bioidentical Hormone Replacement Therapy Individualized Weight Loss Programs Peptide Therapy for weight loss Interested in our NEW Peptide Weight Loss Program? Join today and get all the details here. Join our Women's Peri and Post Menopause Group Coaching Program, OnTrack, TODAY! To our nursing audience members, our podcasts qualify for nursing CE @ RNegade.pro. Provide # CEP17654. Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert Karen's Facebook Karen's Instagram
Dr. Hoffman continues his conversation with Neil Levin, Senior Nutrition Education Manager for Protocol for Life Balance (PFLB) and Now Foods.
Enhancing Joint, Muscle, and Bone Health Through Nutrition: Expert Insights with Neil Levin, Senior Nutrition Education Manager for Protocol for Life Balance (PFLB) and Now Foods. They delve into why people over 40 experience aches and pains and offer strategies to mitigate these issues through nutrition. The conversation covers the importance of teaching nutrition to medical students, the role of various nutrients in pain relief and inflammation, and the benefits of specific supplements such as Omega-3s, curcumin, and collagen. Neil shares his personal experiences with supplements and provides insights on choosing the right curcumin formulations for different health concerns. The episode emphasizes the necessity of a balanced approach to nutrition for maintaining joint, muscle, and bone health, especially as we age.
If you're struggling with chronic health conditions, you're not alone. In this episode, four patients from our clinic share their health journeys and the solutions we've discovered to unlock real healing. From digestive issues to SIBO, hormone imbalances and mold toxicity, you'll learn the missing diet and supplements that finally helped them. Listen now! Start healing with us! Learn more about our virtual clinic: https://drruscio.com/virtual-clinic/
I thought I had it all figured out.I'm a hormone expert, fitness model, and I've had a full hysterectomy—so I should know what I'm doing.But I kept feeling off.Knees aching like I was 80Cellulite showing up in new placesBody holding fat even though I was showing up, lifting, eating cleanIt wasn't until I asked Hotmomz AI™ to audit my hormone setup that I found the real leak: ➡️ Estrogen was too high ➡️ Progesterone was too low ➡️ My nervous system was stuck in survivalThis episode is a behind-the-scenes look at how I recalibrated everything using the tool I created. You'll hear exactly how it works, what I changed in real time, and why this AI is replacing the need for plans, fitness apps, or even coaches.If your knees hurt, your energy is flat, or your body's not responding—even though you're doing everything right—this is for you.Support the showThe Hotmomz AI 30-Day Trial [CLICK HERE]Ready to be hot, healthy, and struggle-free? Join the Hotmomz Mastermind $999/year or $64 month → CLICK THIS LINK • Connect with me on Instagram: @caseyshipp• The Quick Fix (4 Weeks. Cravings Gone. Bloat Down. Fast Results) → [I'M READY]• Grab my $22 Food Test Course [LINK]
Menopausal hormonal therapy should not be a blanket recommendation for everyone going through menopauseWeight management in women is influenced by hormonal changes throughout life stages.Retrospective analyses can provide insights but have limitations.The wellness industry often oversimplifies complex medical issues.Hormonal replacement therapy may have subtle benefits for weight management.Confounding factors like SSRIs can complicate weight loss efforts.A holistic approach is essential for managing women's health during menopause.Education and awareness are crucial for women navigating menopause.Future research should focus on randomized controlled trials for better clarity.Understanding individual patient experiences is key to effective treatment.Click here to see her studyClick here to follow Dr. Tchang on XClick here to join Dr. Spencer's clinic Vineyard
I'm certainly not educated well enough to say what exactly has led to the dramatic reductions in global testosterone levels, be it plastics, sugars, antibiotics, processed chemicals, or whatever else. However, my guest today is a hormone replacement expert, so we'll find out together! Welcome to the Just Dumb Enough Podcast. A show that acknowledges no one is always an expert, by dispelling misconceptions with real experts. My guest today is Susie Bell. Susie has over three decades of experience helping patients, many of whom struggle to keep their natural hormones in check as the years go on. For women, it's widely acknowledged to be an issue around menopause; but for men, it can happen in your late teens! That's a shock, but so are the many messages that you'll hear actually explained when we give the topic room to explain itself. Thank you so much to everyone in Japan who made the first international tour such an absolute blast! I've never felt 16 days go by so quickly, and I feel I could have spent another hundred days without issue. Hopefully I get to do even more of those big tours in the coming months and years. Tokyo, Nikko, Kyoto, Nara, Osaka, and Okinawa: Seriously, THANK YOU so much! ( Https://Www.GetWellWithSusieBell.Com ) ( https://static1.squarespace.com/static/627d7bbb8f061a4300985c07/t/663cf6a8f150ed30ef08d0bb/1715271336480/Susan+Bell_Memoir_Forward.pdf ) Let's fix our imbalances without shame! As mentioned in the interview, I do know many young men with low Testosterone levels, and that includes myself. Before my father passed away, he and I compared our levels to find that they were almost identical despite being 25 years apart. In ranking news... May wrapped up while we were on tour: 1. The United States, with California, Wisconsin, and Oregon at the top; sorry Ohio. 2. England of the United Kingdom. 3. Australia, with Queensland well over New South Wales. 4. Canada, with Ontario just barely beating British Columbia. 5. South Africa, just beating Ireland. That's it for this week! Have a great week, a great weekend, and I'll see you all back here next week for another new episode! Until the next episode, pretty please do all the things to help the show: rate, review, like, and subscribe. Reach out to DumbEnoughPodcast@Gmail.Com or on any social media if you want to reach me personally. Most importantly, Stay Dumb! #Podcast #Education #HormoneReplacement #Testosterone #GymBro #Semaglutide #Estrodile #Progesterone
It's the second Tuesday of the month, which means host Hiwa Alaghebandian is here to break down current wellness trends. This month we address:does hypochlorous acid make you & your home smell better?does yerba mate tea make you lose weight?does the viral carrot ribbon salad actually balance your hormones?!?PLUS-- the best foods for energy, hormone balance, weight loss, and eliminating body odor!To shop everything mentioned in this episode: https://shopmy.us/collections/1780425As always, if you enjoy this episode, please make sure you are subscribed to the show to hear more, leave a 5-star review telling us what you liked about it, and please share with your community who you think would benefit from the episode.The INAPPROPRIATE & UNPROFESSIONAL MERCH COLLECTION IS LIVE!!! Get your cute threads here.The BLUSH ACADEMY 2.0 IS HERE!!! Join now to get access to every single Blush Academy course & digital product-- including: the Attachment Styles coursethe Nervous System Regulation courseall of the Neural ReWiring Practices & breathwork sessionshundreds of healthy recipesthe upcoming Gut Health course & Inner Child Healing coursethe Q&A service & weekly bonus contentall for a low monthly fee. This membership has every single tool & resource that you need to look your best, feel your best, and BE the best version of yourself. Click here to join.If you have any questions you want answered on the podcast, submit them to theblushpod@gmail.com or LEAVE A VOICEMAIL. You can also submit anonymously here.Follow us on instagram:instagram.com/blushpodinstagram.com/hiwaaaaaaaa
Forever Young Radio Show with America's Natural Doctor Podcast
We have a great episode planned and will focus on Men's Health with a highlight on Hormones. Men are just as vulnerable as Women to having hormonal imbalances or even hormonal issues, but it is just not talked about enough. Today we will talk about who, what, when and where.Talking Points:-Why do men need testosterone?Testosterone is a hormone that plays a vital role in men's health. Low or deficient levels are associated with fatigue, weight gain, muscle and bone mass loss, low libido, depression, impotence, poor memory, and other symptoms.There are many reasons why men can have low testosterone.-How common is Low Testosterone?Low or deficient testosterone in males is problematic in America. According to the Cleveland Clinic, low testosterone affects almost 40% of men aged 45 and older! Testosterone deficiency negatively affects a man's quality of life and is a known risk factor for early death. Testosterone levels are at their highest levels by early adulthood and then decrease by 1% to 2% a year beginning in the 40's.-What causes Low Testosterone?I find that testosterone deficiency or sub-optimal testosterone levels are common in both men and women. If your testosterone levels are low, then you may experience:FatigueLow libidoPoor memory and concentrationLoss of muscle massLoss of bone massIncreased body fatPoor exercise recoveryElevated cholesterol levelsDepressionDecreased resistance to stressErectile Dysfunction (men)Increased heart disease risk-Are there certain foods that can raise or lower Testosterone?-Estrogen Dominance in Men-Let's move on and talk about the Prostate. What is Benign prostatic hyperplasia (BPH?-ROOT CAUSES-How Common-Can it lead to Hormone Imbalance?-ED and Low Libido-Bladder and urinary tract issues?-Any Supportive Supplements for Men dealing with lower Testosterone levels?There are not many supplements proven to increase men's testosterone levels. However, a unique extract of the ayurvedic herb known as ashwagandha has been shown in several studies to elevate male testosterone levels.The ashwagandha extract known as KSM-66 was shown in a recent study to significantly increase blood testosterone levels and sexual well-being. The study involved fifty participants with low sexual desire who were given KSM-66 at a dose of 600 mg or placebo daily. Outcomes were measured with a questionnaire and blood testosterone levels at the beginning and end of the 8-week study. Compared to the placebo, the KSM-66 demonstrated significant benefits.The ashwagandha extract in this study is the same one I use in Testosterone Health (which has 675 mg of KSM-66 per serving). This supplemental approach gives men the potential to improve their libido and testosterone levels without prescription testosterone.-Does Saw Palmetto Really Help the Prostate?Learn more about Dr.StenglerLearn more about Emerald Labs and save 20% off with the code: Forever
Episode Highlights With SharonWhy we can forget the pause part of menopause and why this can mean much more than just the pause or end of the menstrual cycleThis is a physiological process and also an important emotional and spiritual inflection pointWhy she suggests women write their eulogies at this age as a way to recenter How to reverse engineer the life we want to have as we go through menopauseThe different ways that other cultures approach menopause and how this even impacts the physical experience of aging and menopause Menopause is not a disease but a natural (and beautiful) transitionThe story of the adrenal glands picking up the slack to produce hormones and why this isn't the full storyHow to support the body, mind, and spirit through perimenopause and menopauseSome tactical and practical things we can do to support our bodies as we age and what to know about hormones and when they're helpfulBig misunderstandings about hormone replacement for womenEstrogen should never be taken orally but transmucosally How to check metabolites and how this is important to know for hormone replacementWays to support the adrenals, especially as we age, and why cortisol isn't actually usually the problemResources MentionedDr. Sharon's websiteFind her on Facebook and Instagram
Keeping the Prostate healthy is important as men age. Prostate Cancer is the #1 Cancer in Men, which includes "almost all men over the age of 80". In this episode, you'll discover:—How keeping your Testosterone levels up can help prevent Prostate Cancer. And why Dr. Prather believes men don't "completely function well" outside of Prostate numbers in the 800-900 range. —The Benign Prostatic Hypertrophy (BPH) condition that creates an enlargement of the Prostate and is caused by Estrogen dominance. —The reason Dr. Prather was not surprised to hear that former President Joe Biden had Prostate Cancer. And why he would not be surprised if President Donald Trump has it, too. —Why Diet, particularly increased Fiber, and Exercise are so important for Prostate Health. And why it's important to eliminate toxins like heavy metals, infections, and parasites that can kick off Cancer in the body.—How a Native American herbal formula first developed by Hiawatha is still used by Dr. Prather for his patients to help detox the body. And why Dr. Prather says that it's something "almost everyone who has Cancer should be taking".—The Vitamins, Minerals, Herbals, and Homeopathics that are most helpful for Prostate health and for lowering side-effects from Chemotherapy. And how the Prostate contains the highest concentration of Zinc in the human body and is "critical" for Prostate health.—Why Dr. Prather predicts this generation of young men will have increased rates of Prostate Cancer due to Marijuana use. —The instantaneous relief Acupuncture provides for those suffering from Prostatitis. And why you shouldn't be afraid of where Dr. Prather puts the needles! —The amazing story of a terminal Prostate Cancer patient sent by his oncologist to Dr. Prather for pain relief through Acupuncture. And why the oncologist called to ask what Dr. Prather was doing to the patient after seeing the patient's PSA numbers plummet. —How just preventing a patient from becoming Anemic during Cancer treatment can increase their survival chances by 50%. And how keeping the Liver clean during Cancer treatment can increase their chance of survival by another 25%.http://www.TheVoiceOfHealthRadio.com
We tend to think of women's health as it relates to getting pregnant, not physical health or even health later on in life, but Caitlin and Laura sit down to discuss how estrogen impacts everything from bone health to cognitive function, and why it's vital for both reproductive and overall well-being. We talk about natural ways to improve estrogen levels (like weight-bearing exercises) and how maintaining healthy estrogen levels can protect us well into our later years. Whether you're in your 20s or approaching menopause, this episode offers valuable information on how to support your health through every stage of life. NOTE: This episode is appropriate for all audiences. Our guest, Laura Ducote, is a Family Nurse Practitioner with training in NaProTechnology and is currently a FertilityCare Practitioner at Woven Natural Fertility Care. Ways to connect and work with Laura:Work with Laura as a Fertility Care PractitionerWork with Laura as a Nurse PractitionerOther episodes you might enjoy:Ep. 164: Insulin Resistance impacts more than your fertility and it's affecting younger women--what can you do? Ep. 156: Using DHEA to naturally increase hormones and fertility, with Laura Ducote Ep. 31: The Napro Difference, with Laura Ducote, F-NP, FCPEp. 3: BASICS--Reproductive HormonesEp. 135: Can I trust Natural Birth Control?Send us a textSupport the showOther great ways to connect with Woven Natural Fertility Care: Learn the Creighton Model System with us! Register here! Get our monthly newsletter: Get the updates! Chat about issues of fertility + faith: Substack Follow us on Instagram: @wovenfertility Watch our episodes on YouTube: @wovenfertility Love the content? The biggest gift you could give is to click a 5 star review and write why it was so meaningful! This podcast is provided for educational and informational purposes only and does not constitute providing medical advice or professional services. The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician. Always seek the advice of your doctor or other qualified health provider regarding a medical condition. If you think you may have a medical emergency, call 911 or go to the nearest emergency room immediately. Neither Woven nor its staff, nor any contributor to this podcast, makes any represe...
In this episode, Dr. Sanda hosts Dr. Myra Reed to discuss the critical link between heart disease and oral health, particularly in women. They explore the journey to functional medicine, the importance of advanced testing, and the unique risk factors women face regarding heart disease. The conversation delves into the impact of stress, the role of estrogen, and the significance of hormone management. Additionally, they highlight the connection between oral health and heart disease, the dangers of mercury toxicity, and the importance of finding the right healthcare provider. The episode concludes with a discussion on the benefits of omega-3s for heart health. Want to see more of The Holistic Dentistry Show? Watch our episodes on YouTube! Do you have a mouth- or body-related question for Dr. Sanda? Send her a message on Instagram! Remember, you're not healthy until your mouth is healthy. So take care of it in the most natural way. Key Takeaways: (00:00) Introduction to Heart Disease and Oral Health (01:09) The Journey to Functional Medicine (02:40) Advanced Testing for Heart Disease (05:22) Understanding Risk Factors for Women (10:12) The Impact of Stress on Heart Health (12:24) Recognizing Heart Disease Symptoms in Women (13:48) The Role of Estrogen in Heart Health (16:33) Hormone Testing and Management (20:34) The Connection Between Oral Health and Heart Disease (24:41) The Importance of Biological Dentistry (26:46) Sleep Apnea and Heart Disease (34:26) Mercury Toxicity and Heart Health (39:04) Finding the Right Doctor for Heart Health (42:30) The Benefits of Omega-3s for Heart Health Guest Info Myra Reed MD Instagram https://www.instagram.com/drmyrareed/ Website - https://drmyrareed.com Facebook https://www.facebook.com/drmyrareed Youtube https://www.youtube.com/@dr.myrareed1768 Connect With Us: AskDrSanda | YouTube BeverlyHillsDentalHealth.com | Instagram DrSandaMoldovan.com | Instagram Orasana.com | Instagram
Everyone thinks hormone therapy is finally getting attention but no one's really talking about the fact that estrogen can be life-saving. The data is right there: lower mortality, fewer hospitalizations, less sepsis. So why is it still being overlooked?In my practice, I see patients every day who are silently suffering dealing with UTIs, vaginal dryness, painful sex, and bladder issues they think are just part of aging. But these symptoms often point to something much bigger: Genitourinary Syndrome of Menopause. And what's worse, it's still widely misunderstood or ignored.A recent study with new data stopped me in my tracks. Over 11 million patient records showed that vaginal estrogen doesn't just improve quality of life it dramatically reduces serious outcomes like sepsis and even death. That kind of impact should be front-page news in every medical journal, yet here we are… still debating whether it's “necessary.”We also talked about the brand new AUA guidelines, which now make it clear: local estrogen is first-line therapy. It's safe, even for many patients who were once told they couldn't use hormones. These guidelines finally reflect what we've known clinically for years that low-dose vaginal estrogen isn't just symptom relief. It's prevention.There's still a lot of confusion about systemic absorption, cancer risk, and when to refer out. So in this episode, I'm breaking down what's new, what's misunderstood, and what every patient and provider needs to know. I'm also sharing how I approach treatment options from estrogen and DHEA to pelvic floor therapy and even energy-based devices (yes, we go there).If you've ever been told this is just part of aging, or you're not sure what your options are, I hope this gives you clarity—and maybe a little validation, too. Highlights:Why vaginal estrogen can lower mortality, sepsis, and hospital stays.What the AUA's 2025 GSM guidelines say—and why they matter.Clearing up myths about hormone absorption and cancer risk.When to consider DHEA, Ospemifene, or non-hormonal options.The role of pelvic floor therapy in managing GSM.Resources:AUA's GuidelinesGyno Girl-GSM VideoGet in Touch with Dr. Rahman:WebsiteInstagramYoutube
In this episode, I'm joined by Dr. Vincent Esposito for a thought-provoking conversation that explores both our differences and shared values in the health space. While we don't align on every aspect of nutrition, we absolutely agree on the importance of questioning conventional wisdom, especially when it comes to antibiotics, hormone health, and taking ownership of your well-being. We explore topics like high-protein diets, the impact of artificial light on sleep, and why a one-size-fits-all approach to health often falls short. Topics Discussed: What are the risks of a high-protein diet?How does artificial light affect sleep and circadian rhythms?Why is it important to question mainstream narratives about estrogen and hormone health?What role do antibiotics play in long-term health and gut function?How can personal accountability improve your overall wellness journey?Sponsored By: Bon Charge | Click here & use code for SARAHKLEINER for 15% off storewide.Black Lotus Shilajit | Visit: www.blacklotusshilajit.com and Use Code: SARAHK for 15% the entire site!Timestamps: 00:00:00 - Introduction 00:04:56 - Chiropractic school journey + weight loss00:08:10 - Nutrition & dietary shifts00:10:17 - Seed oils, processed food & eating out00:11:59 - Whole food sources vs. macro tracking00:14:44 - Dangers of high-protein diets00:19:57 - Carnivore diet content & lab results00:27:03 - Heart disease, statins & nutrition00:29:50 - Estrogen, hormone health & HRT00:33:42 - Sleep quality & effects of artificial light00:37:53 - Common sleep disruptors00:38:55 - Tips for improving sleep naturally00:40:30 - Sleep patterns & wake-up timing00:41:59 - Seasonal affective disorder (SAD)00:43:35 - Navigating conflicting health advice00:46:26 - Children's health00:48:59 - Why personal health responsibility matters00:51:10 - Aging well 00:54:09 - Building real connections in wellness00:58:04 - Estrogen myths Further Listening: The Biggest Health and Fitness Mistakes People Make in the New Year with Coach Rob JacobsCheck Out Dr. Vincent Esposito: InstagramYouTubeinsideouthealthwellness.com This video is not medical advice & as a supporter to you and your health journey - I encourage you to monitor your labs and work with a professional!________________________________________My free product guide with all product recommendations and discount codes:https://s3.amazonaws.com/kajabi-storefronts-production/file-uploads/sites/2147573344/themes/2150788813/downloads/eac4820-016-b500-7db-ba106ed8583_2024_SKW_Affiliate_Guide_6_.pdfCheck out all my courses to understand how to improve your mitochondrial health & experience long lasting health! (Use code PODCAST to save 10%) - https://www.sarahkleinerwellness.com/coursesSign up for my newsletter to get special offers in the future! https://www.sarahkleinerwellness.com/contact
This week on Health Matters we reflect on the top health tips and takeaways from our May series dedicated to Women's Health Month. Courtney is joined by Angelique Serrano to talk more about how to care for our skin, bone, and brain health, as well as ways to recognize and manage perimenopause symptoms. In their conversations with Health Matters, neurologist Dr. Sonja Blum and dermatologist Dr. Shari Lipner shared small daily habits that can make big contributions to long term health. Dr. Mary Rosser, an OB-GYN, shares a process for tackling sleep issues during perimenopause. Physiatrist Dr. Erica Eldon explains the importance of bone strength and how to prevent ailments like a broken hip. Courtney and Angelique share how the advice from NewYork-Presbyterian doctors opens space for women to discuss health care decisions in ways that are often overlooked and how they are inspired to prioritize their own health.___Health Matters shares stories of science, care, and wellness from NewYork-Presbyterian, one of the nation's most comprehensive healthcare systems.NewYork-Presbyterian's Health Matters features the latest news and insights from our world-class physicians, nurses, and experts; inspiring first-hand accounts from patients and caregivers; and updates on the latest research and innovations in patient care, all in collaboration with our academic partners Columbia and Weill Cornell Medicine.To learn more visit: https://healthmatters.nyp.org/
The literature shows that the incidence of heart failure with preserved ejection fraction (HFpEF) increases significantly in postmenopausal women, but how can researchers study the underlying mechanisms? In our latest episode, Dr. Jonathan Kirk (Loyola University Chicago) interviews lead author Dr. Mei Methawasin (University of Missouri, Columbia) and expert Dr. Glen Pyle (University of Guelph) about the recent study by Methawasin and co-authors investigating sex differences, menopause and HFpEF. The authors created an animal model that resembles HFpEF in women undergoing natural menopause by using 4-vinylcyclohexene dioxide (VCD) to induce “ovary-intact” menopause, combined with the 2hit regimen (HFpEF inducing regimen) to model postmenopausal HFpEF. Combining echocardiography, pressure-volume and single-cell analyses, the authors found that VCD mice, compared to ovariectomized mice and premenopausal mice, have higher testosterone levels compared to other models. By developing this robust phenotype animal model, the authors open new avenues for investigating therapeutic targets in other hormones beyond estrogen alone. Ready to explore the estrobolome, the importance of animal models of human disease, and the complex family of hormones comprising estrogen? Listen now. Mei Methawasin, Joshua Strom, Vito A. Marino, Jochen Gohlke, Julia Muldoon, Shelby R. Herrick, Robbert van der Piji, John P. Konhilas, Henk Granzier An ovary-intact postmenopausal HFpEF mouse model; menopause is more than just estrogen deficiency Am J Physiol Heart Circ Physiol, published March 10, 2025. DOI: 10.1152/ajpheart.00575.2024
If you're maintaining a healthy lifestyle—regular exercise, balanced nutrition, minimal alcohol—and still experiencing fatigue, weight fluctuations, digestive issues, and hormonal symptoms, you're not alone. This was Jenny's experience. After two years of persistent health challenges, she came to us as a last resort. She had already spent thousands of dollars on care that didn't produce results. No comprehensive testing. No targeted interventions. Just more supplements and generic advice. Her case wasn't unusual. What made the difference was data. Through our 1:1 program, Jenny completed a full panel of functional assessments, including: Hormone & adrenal testing (DUTCH test) Comprehensive gut analysis Nutrient and inflammatory markers Genetic testing to understand her body's metabolic and detox pathways The findings confirmed several core issues: Severely diminished cortisol output Estrogen dominance with low progesterone production Leaky gut and poor gut microbiota diversity Methylation and detoxification gene variants contributing to poor recovery and persistent inflammation Once we had this information, we developed a structured plan with targeted interventions to support endocrine function, rebuild gut integrity, and address her specific genetic vulnerabilities. Within weeks, she began to notice improvements: more stable energy, clearer cognition, better sleep, and less bloating. While she's still progressing through the program, the results so far validate a simple principle: symptoms require investigation—not assumption. If you've been told “everything looks normal” but still don't feel well, you may benefit from the same thorough, data-driven approach.
Today, I am delighted to reconnect with my friend and colleague, Dr. Amy B. Killen, a board-certified physician with expertise in bioidentical hormones, personalized medication, and cutting-edge rejuvenation techniques. In our conversation, we dive into the spectrum of progesterone sensitivity, exploring why estrogen is considered the best longevity drug available and how it reduces the risk of heart disease. We discuss bone health and bioidenticals, outline ways to improve cognition, brain function, and cardiovascular health, and examine the ongoing debate around oral estrogen therapy. Dr. Amy also sheds light on slowing ovarian aging, explains the concept of hair pause and how to address it proactively, and offers her take on overrated or ineffective strategies for navigating perimenopause and beyond. You will not want to miss this insightful episode with Dr. Amy Killen, and I look forward to having her back for another conversation. IN THIS EPISODE, YOU WILL LEARN: Dr. Amy sheds light on the spectrum of progesterone sensitivity. Progesterone treatment options for women with progesterone sensitivity Why estrogen is crucial for longevity How estrogen protects the heart and blood vessels, reducing the risk of cardiovascular disease When is the best time to start taking estrogen for optimal cardiovascular benefits? Estrogen and bone strength and flexibility Can starting estrogen treatments early help prevent dementia and cognitive decline? Pros and cons of using a combination of estriol and estradiol Slow ovarian senescence and prevent hormonal changes from affecting your hair health. Bio: Dr. Amy B. Killen, M.D., is a leading physician in regenerative and hormone optimization medicine, specializing in women's health and helping patients navigate their "Queen PhaseTM" with evidence-based interventions. As a board-certified emergency physician turned longevity specialist, she combines cutting-edge treatments, such as stem cell therapy, hormone optimization, and peptides, with practical lifestyle wisdom at her clinics in Utah and Texas, while sharing her expertise through international speaking engagements and educational content creation. Dr. Killen is the Chief Medical Officer of Humanaut Health, a longevity clinic franchise, and founder of the Human Optimization Project (HOP), a female-focused supplement company. She lives in Salt Lake City with her family of five. Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Connect with Dr. Amy Killen On her website HopBox (Supplement Company) Subscribe to Dr. Amy's Substack
Kate Moryoussef is the host of award-winning and chart-topping The ADHD Women's Wellbeing Podcast, a women's ADHD Lifestyle & well-being coach, EFT practitioner, and NOW author, helping burnt-out, overwhelmed, and unfulfilled newly-diagnosed ADHD women find more calm, balance, hope, wellbeing, compassion, creativity and clarity. In this episode, Kate Moryoussef shares tips on how to navigate ADHD as a woman, including hormone replacement therapy, the connection with the various phases of the menstrual cycle, and provides resources for learning more to determine if you have ADHD. Learn more about Kate here: https://www.adhdwomenswellbeing.co.uk/ Instagram: @kate_moryoussef Listen to her podcastThe ADHD Women's Wellbeing Podcast here: https://www.adhdwomenswellbeing.co.uk/adhd-podcast Pre-order her book The ADHD Women's Wellbeing Toolkit here: https://www.adhdwomenswellbeing.co.uk/adhd-womens-wellbeing-toolkit Get 15% off Peluva minimalist shoe with coupon code COACHTARA here: http://peluva.com/coachtara CHAPTERS: 0:00 Intro 4:45 What life was like for Kate before realizing she had ADHD 10:43 Menstrual cycle and ADHD 18:30 Estrogen and progesterone for ADHD 27:45 Sensibility of the nervous system with ADHD 42:15 Find out if you have ADHD 49:00 Resources from Kate
Dr. David Lans is an integrative longevity physician who harnesses the power of hormones to unlock vitality and lifelong health.New episodes of Welcome to Wellness every Friday!Not listening on Spotify? Show notes at: https://www.ashleydeeley.com/w2w/drdavidlansEpisode brought to you by: ApolloNeuroEpisode brought to you by: VieLight - Code: DEELEY10Episode brought to you by:Dry Farm Wines 6:36: Women in their 40s will begin to experience some hormone fluctuations10:33: Tips on progesterone (tip: DO NOT take progesterone every day of your cycle!)15:30: Why oral progesterone will help you sleep (hint: enzymes are released from the liver for a slow release effect)17:48: Prescribing estrogen without progesterone is malpractice (at least if you still have a uterus)22:31: Never take Estrone or Tri-Est27:00: Estrogen is brest protective42:03: Hormones help with your mood, cognition, and memory47:26: Ways to take hormones (modalities such as creams, trochees, pellets, etc.,)49:57: When you start taking hormones, you want to take them for the rest of your life!Where to find Ashley Deeley:WebsiteInstagramFacebookYouTubehello@ashleydeeley.com
Don't you love when an older family member lectures you about something that doesn't involve them? One of our listeners didn't just smile and nod when her aunt asked a question about an item in the fridge, and now she wants complete anonymity in order to come clean about it!See omnystudio.com/listener for privacy information.
214: In this episode, I'm diving into all things histamine—what it is, how it functions, and why it might be the missing link in your hormone and immune health journey. After sharing insights on the connection between histamine sensitivity and hormone replacement therapy (HRT), the response was massive. I'm unpacking why histamine issues are more than just food reactions, how they relate to estrogen, menopause, and chronic inflammation, and why there's no one-size-fits-all solution. I've dealt with histamine challenges my whole life and supported countless patients through it. This episode is a deep, honest look at the bigger picture behind histamine imbalance. Topics Discussed: What are the symptoms of histamine intolerance and how is it connected to hormone imbalances? How does histamine affect estrogen levels and hormone replacement therapy (HRT)? What causes high histamine levels and how can you support balance naturally? What is the difference between histamine intolerance and mast cell activation syndrome (MCAS)? How do lifestyle factors, diet, and gut health influence histamine sensitivity? Sponsored By: Nutrisense | Head over to nutrisense.io/drtyna to get 30% off your Nutrisense plan. Code TYNA at checkout Puori | Go to Puori.com/drtyna and use code DRTYNA to get 20% off Timeline | Timeline is offering 10% off your order of Mitopure Go to timeline.com/drtyna LVLUP | Head over to LVLUPHealth.com and use code DRTYNA at checkout to get 20% off your order sitewide. LMNT | Get your free Sample Pack with any LMNT purchase at drinkLMNT.com/drtyna Liver Love | Go to https://store.drtyna.com/products/liverlove Use code LIVER20 for 20% off On This Episode Cover: 00:00:00 – Introduction 00:01:57 – Histamine and Your Immune System 00:06:01 – Mast Cells, Allergies, and Inflammation 00:09:55 – My Personal Histamine Story 00:12:38 – Why Histamine Acts Fast 00:15:01 – The Role of Histamine in the Body 00:19:55 – Histamine Intolerance vs. MCAS 00:24:19 – How Menopause Impacts Histamine 00:26:32 – Why Your Histamine Is Out of Balance 00:28:20 – DAO Deficiency Explained 00:32:37 – DAO Blockers and High-Histamine Foods 00:34:32 – Lifestyle Stressors and Chronic Illness 00:36:19 – Common Mast Cell Triggers 00:42:08 – Top High-Histamine Foods 00:43:36 – What Are Histamine Liberators? 00:44:42 – Estrogen, HRT, and Histamine 00:48:10 – Histamine and Metabolic Dysfunction 00:48:34 – Recognizing Histamine-Related Symptoms 00:51:22 – My Clinical Insights on Histamine 00:54:50 – GLP-1 Meds, Histamine, and MCAS Show Links: GLP1 Uncovered Find A Doc Further Listening: EP 41: Dangers of NSAIDS - Solo Episode EP. 199 | Hot Flashes Are a Warning Sign: The Truth About Metabolic Dysfunction | Quick + Dirty EP 106: GLP1 Done Right Part 1 | Solo Episode Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease
A bite-sized boost to your day! This mini is an excerpt from episode 403 with Dr. Kelly Casperson with a focus on the wide-ranging benefits of vaginal estrogen for women.
THE BETTER BELLY PODCAST - Gut Health Transformation Strategies for a Better Belly, Brain, and Body
Happy last Thursday in May! As we round out the end of May, I (Allison) am finishing up the last week of my maternity leave! To celebrate this, we're pulling content from our group coaching calls inside our private coaching group, the Better Belly Blueprint, to share with YOU. Today's topic is from my client Melissa. She asked: "My previous functional medicine provider put me on a supplement for my estrogen dominance about a year ago. Since then, I have been taking I-3-C Plus Dim and Calcium-D-Glucarate everyday. I feel that it has helped me so much with my PMDD symtoms as well as gallbladder symptoms and notice a difference when I miss doses. Do I need to stop taking this for awhile when I do my DUTCH test? Would this skew the results? I can stop taking if needed but don't want to if I don't have to." Melissa's question comes from a desire to not waste money on functional lab testing by getting results that aren't even relevant or trustworthy. Yet, she also doesn't want her symptoms to come BACK by going off a supplement she's found SUPER helpful. What is Melissa to do? If you've ever been in a similar bind of wanting to do a lab test but feeling nervous about going off supplements or medications - then this episode is for you! P.S. ~ If you want to ask questions to me JUST LIKE THIS ONE and get my live feedback, now you can! When you join the Better Belly Blueprint and add on group coaching for our SUPER affordable price, you get access to live, bi-weekly group coaching calls just like this one AND unlimited, daily, 1:1 coaching inside our private FB group! Enrollment is open now - there's no need to wait! Go to https://betterbellytherapies.com/blueprint to read more about BBB and join today! Or - if you prefer to learn via audio and video, go to https://betterbellytherapies.com/training and watch the FREE training I put together on why and how BBB helps you overcome your toughest symptoms - even when nothing else prior to this has worked! Are you ready to hear Melissa's answer? Let's dive in! TIMESTAMPS:00:00 - Introduction and Personal Update 00:17 - Client Question: Estrogen Dominance Supplements 00:52 - Concerns About Stopping Supplements for Testing 01:14 - Invitation to Join Better Belly Blueprint 02:01 - Welcome to the Better Belly Podcast 03:06 - Discussion on Estrogen Dominance and Supplements 04:50 - Addressing Long-term Supplement Use 06:11 - Client's Experience and Next Steps 07:45 - Concluding Remarks and Data Importance RELATED EPISODES:26// Is your period out of whack?! 3 Pathways that Link Gut Health to Hormonal Health – with Sophie Shepherd FDN-P198// 2 Natural Perimenopause Support Strategies for Any Age196// How to Have a Pain Free Periods, End...
Estrogen & Histamine Brain Fog & Irritability Hidden Hormone Trap | Podcast #454
Do cell phones cause brain cancer? Does using an antiperspirant increase the risk of breast cancer? Does fluoride in the water increase the risk of bone cancer? Is the HPV vaccine lifesaving or dangerous? In this episode, I am joined by Dr. Shikha Jain, an academic hematologist and oncologist. We start by busting cancer myths and then move on to discuss the impact of the “Make America Healthy Again Movement” (MAHA)on cancer care and cancer research, and why the rationale behind the MAHA movement is FLAWED and DANGEROUS. Which of the following is associated with getting cancer or spreading cancer Biopsies Specific viruses Consuming sugar Mammograms Living near a Power line Cell phones Deodorant and antiperspirants Microplastics Microwaving If surgery to remove a cancerous growth spreads the cancer? Estrogen- birth control pills, local estrogen, systemic estrogen The impact of current political policies on cancer treatment and research Obesity Processed food HPV vaccine Fluoride in the water The financial incentive behind the MAHA movement Why placebo-controlled trials are not always used in research, and would be dangerous Defunding of NIH Cancer Research, including labs and clinical trials The US Brain Drain Over 9.5 billion dollars, representing over 2000 NIH grants, have been terminated. In the links below, expand the abstract column to see the details of the research. List of NIH grants that have been defunded https://airtable.com/appjhyo9NTvJLocRy/shrNto1NNp9eJlgpA? Ffj6Q%3Aview=plasNjSudszRmPvEo&Ffj6Q=allRecords List of NIH Cancer Research that Has Been Defunded https://airtable.com/appjhyo9NTvJLocRy/shrNto1NNp9eJlgpA?Ffj6Q=sfsqqf7AYxKbZi37s&Ffj6Q%3Aview=plasNjSudszRmPvEo Dr. Shikha Jain, MD, FACP, is a board-certified oncologist, national health media contributor, and founder of Women in Medicine®. She's a tenured associate professor at the University of Illinois and was named Illinois Physician Leader of the Year, one of Modern Healthcare's Top 25 Emerging Leaders, and a Medscape Rising Star in Medicine. Through her clinical work, national advocacy, and powerful storytelling, Dr. Jain is transforming how we think about medicine, leadership, and the future of healthcare. https://www.wimedicine.org/ https://www.wimedicine.org/wim-summit https://shikhajainmd.com/ How to Know an Expert is an Expert Episode 157: How to Find a Clinician that's Not Clueless Substack Posts A Guide to Finding a Menopause Clinician That's Not Clueless Let's Play…Is Your Doctor Really a Menopause Expert? Dr. Streicher is on SUBSTACK DrStreicher.Substack.com Articles Monthly newsletter All COME AGAIN podcast episodes Monthly News Flash Reports on recent research Monthly Zoom Ask Me Anything Webinar Information on Dr. Streicher's COME AGAIN Podcast- Sexuality and Orgasm Lauren Streicher MD, is a clinical professor of obstetrics and gynecology at Northwestern University's Feinberg School of Medicine, the founding medical director of the Northwestern Medicine Center for Sexual Medicine and Menopause, and a Senior Research Fellow of The Kinsey Institute, Indiana University. She is a certified menopause practitioner of The Menopause Society. She is the Medical Director of Community Education and Outreach for Midi Health. Dr. Streicher is the medical correspondent for Chicago's top-rated news program, the WGN Morning News, and has been seen on The Today Show, Good Morning America, The Oprah Winfrey Show, CNN, NPR, Dr. Radio, Nightline, Fox and Friends, The Steve Harvey Show, CBS This Morning, ABC News Now, NBCNightlyNews,20/20, and World News Tonight. She is an expert source for many magazines and serves on the medical advisory board of The Kinsey Institute, Self Magazine, and Prevention Magazine. She writes a regular column for The Ethel by AARP and Prevention Magazine. LINKS Subscribe To Dr. Streicher's Substack Information About the COME AGAIN Podcast Dr. Streicher's CV and additional bio information To Find a Menopause Clinician and Other Resources Glossary Of Medical Terminology Books by Lauren Streicher, MD Slip Sliding Away: Turning Back the Clock on Your Vagina-A gynecologist's guide to eliminating post-menopause dryness and pain Hot Flash Hell: A Gynecologist's Guide to Turning Down the Heat Sex Rx- Hormones, Health, and Your Best Sex Ever The Essential Guide to Hysterectomy Dr. Streicher's Inside Information podcast is for education and information and is not intended to replace medical advice from your personal healthcare clinician. Dr. Streicher disclaims liability for any medical outcomes that may occur because of applying methods suggested or discussed in this podcast.
Doro and Tricia welcome Dr. Mariza Snyder, an expert on perimenopause and menopause. Dr. Snyder gives an overview of women's wellness research, highlighting the misconceptions surrounding the Women's Health Initiative and the need for a more holistic approach to women's health, particularly regarding hormone replacement therapy. Dr. Snyder talks about the roles of estrogen and progesterone, the significance of metabolic health, the impact of hormonal changes during menopause, muscle health, and the impact of stress and trauma on overall well-being. She outlines the significance of nutrition, lifestyle choices, and health-technology in managing these changes and promoting hormonal health, guiding listeners towards a healthier path as they enter the stages of perimenopause and menopause.
What actually works for healthy, vibrant skin—and what's just hype? In this episode, we sit down with the brilliant and refreshingly honest Dr. Mary Alice Mina, Harvard-trained dermatologist and host of The Skin Real podcast. We dive deep into what midlife skin really needs, what treatments are worth the money, and how hormonal changes can shake up everything we thought we knew about our skincare routines.Together, we unpack skin minimalism, sunscreen truths (spoiler: it really matters), and the difference between aging gracefully and chasing the next trending procedure. We also get personal—sharing our own frustrations about neck bands, droopy brows, and that “face falling” feeling—and ask Dr. Mina everything from estrogen creams to slugging and Botox. Episode Highlights:[0:02] - Welcoming Dr. Mary Alice Mina and diving into hormonal changes and midlife skin shifts.[3:38] - Our own candid stories about "face falling" and dry, aging skin.[5:00] - The psychological toll of aging and the importance of internal confidence.[8:10] - What “skin minimalism” actually means—and why less really can be more.[11:37] - Estrogen's role in skin hydration and how perimenopause changes everything.[13:53] - Sunscreen strategy: how often to reapply, the importance of hats, and Dr. Mina's favorite brands. [19:07] - Retinoids 101: how and when to use them for best results. [20:26] - All about neck bands: what works (and what doesn't). [26:09] - Estrogen creams for the face: what Dr. Mina prescribes and how it works. [28:58] - Why sleep is skin care and how sleep deprivation shows up on your face. [30:58] - Sunscreen myths, TikTok fads, and Dr. Mina's biggest dermatology pet peeves.[33:59] - Genetics vs. skincare habits—what really makes the difference.[40:16] - Starting or restarting retinoids without overwhelming your skin.[40:39] - Why annual skin checks are essential and how to talk to your dermatologist.[43:31] - How to connect with Dr. Mina and find your “skin style” through her quiz. Resources:Dr. Mary Alice Mina's Podcast: The Skin RealFind your skin style quiz: https://www.theskinreal.com/style Skincare Compounding: Skin Medicinals (estriol cream)Sunscreen favorites: EltaMD, La Roche-Posay, Neutrogena StickInstagram: https://www.instagram.com/drminaskin Facebook: https://www.facebook.com/drminaskinYouTube: https://www.youtube.com/@drminaskinTitktok: https://www.tiktok.com/@drminaskinMedium: https://medium.com/@drminaskinLinkedIn: https://www.linkedin.com/in/drminaskin/Pinterest: https://www.pinterest.ph/06k6qtsxj4uvtpulz6w5ghdc8l2gwo/Make sure to visit the “Resources” page on our website www.insightsfromthecouch.org to download the worksheet and take ways that accompany each episode. This is hugely important as we are now creating a download that is unique to each episode and working hard to create an email list to support our programming offerings moving forward.
If you're feeling anxious, exhausted, gaining weight, and like nothing is working anymore, this episode is for you. These symptoms aren't just about hormones; they're often signs of a dysregulated nervous system. In this episode, Functional Health & Integrative Nutrition Coach Claudia Petrilli, breaks down how your nervous system impacts hormones, metabolism, sleep, mood, and more during perimenopause. You'll learn why so many women over 40 feel stuck in survival mode and what you can start doing right now to calm your nervous system, reclaim your energy, and feel like yourself again. In this episode, we cover: Why your nervous system matters more than ever in midlife How chronic stress affects cortisol, thyroid, estrogen, and progesterone Why feeling “tired but wired” is a sign your body is stuck in fight-or-flight How trauma wires your system for stress What a healthy cortisol rhythm should look like (and how to support it) 5 simple ways to regulate your nervous system today
During the ten plus years of the menopausal process, it's biological changes, not lifestyle, that reshapes the body, like accumulating fat in the midsection. Menopausal fat is nearly impossible to eradicate with diet and exercise. It requires non-invasive body contouring technology. Learn about the biological processes that cause weight gain, discover why menopausal fat accumulates in the midsection and find out how our treatments using the 6 in 1 Cavitation machine target and reduce menopausal belly fat. All in this episode! CoursesBody Contouring 6-in-1 MasterclassAffiliate Links 6in1 Cavitation Machine on Amazon#ad We are amazon associates, so if you click on a link that is a qualified purchase, we may earn a small fee. It comes as no extra cost to you and we only recommend products based on our experience and/or use.Linkshttps://www.webmd.com/menopause/guide-perimenopause https://www.mayoclinic.org/healthy-lifestyle/womens-health/in-depth/menopause-weight-gain/art-20046058 https://www.endocrine.org/news-and-advocacy/news-room/featured-science-from-endo-2021/sleep-disturbances-may-contribute-to-weight-gain-in-menopause https://healthmatters.nyp.org/how-to-prevent-menopause-weight-gain/#:~:text=Estrogen%20plays%20a%20key%20role,when%20feeling%20emotional%20or%20stressed. https://bodycontouringacademy.com/why-this-ultrasound-fat-cavitation-certification-course-is-smart/ Studies https://www.nia.nih.gov/health/menopause/what-menopause#:~:text=Symptoms%20related%20to%20menopause%20can,culture%2C%20lifestyle%2C%20and%20environment.
Today, I'm joined by Teo Soleymani, MD—a double board-certified dermatologist, fellowship-trained Mohs and facial reconstructive surgeon, and an expert in all things skin cancer—plus, he's as entertaining as he is knowledgeable. If you've ever wondered whether you should slather on sunscreen religiously, or if embracing more sunlight is actually good for you, we're here to offer the clarity and nuance that's so often missing from the conversation. Listeners of this podcast can receive 15% off of SunPowder when you go to sunpowder.co/discount/NAT15 (it's .co not .com or else you won't find it). What we discuss: Sun exposure: fear vs. benefits debate ... 00:06:38 Genetics vs. sun in driving skin cancer risk ... 00:09:04 Types of skin cancer explained ... 00:10:38 HPV, environmental toxins, and non-UV causes ... 00:22:35 Burning vs. safe sun—practical advice ... 00:21:24 Sunscreen: mineral vs. chemical, what matters ... 00:36:01 Problems with spray sunscreens ... 00:40:45 Melanin, UV damage, and skin aging ... 00:13:40 Melasma: hormones and stubborn pigmentation ... 00:47:19 Estrogen, collagen, and topical supplements ... 00:49:18 Astaxanthin and polypodium—internal sun protection ... 00:56:01 Nicotinamide: strong evidence for cancer prevention ... 01:04:11 Sunpowder supplement: trials and benefits ... 01:07:43 Laser resurfacing and reduced cancer risk ... 01:12:33 Genetics, immune health, and testing limits ... 01:15:31 Where to find Sunpowder + connect with Teo ... 01:18:53 Our Amazing Sponsors: LVLUP - Neuro Re-Generate the world's first liposomal triple peptide formula, designed to support mental clarity, focus, and overall brain health. Visit www.lvluphealth.com and use code NAT for 20% off your order. Qualia - Senolytic - Clinically tested formula with 9 plant-based, vegan ingredients designed to help your body clear out zombie cells—so you can feel younger, faster. Visit qualialife.com/nathalie and use promo code NATHALIE to save 15% Young Goose L.A.D.R. Serum - Powered by light-activated DNA repair enzymes, NAD+, and collagen peptides, it reverses damage while you go about your life. Sunlight? Red light therapy? It all helps this serum work smarter, not harder. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer. Future-proof your face. More from Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group More from Teo Soleymani: Website: www.californiadermatology.com and https://sunpowder.co/discount/NAT15 Instagram: @teosoleymanimd Instagram: @drinksunpowder
On this episode of The Wholesome Fertility Podcast, I am joined by Dr. Nirali Jain (eggspert_md), a board-certified OB/GYN and reproductive endocrinologist at Reproductive Medical Associates (RMA). Dr. Jain shares her expert insights on fertility preservation for individuals undergoing cancer treatment, a crucial yet often overlooked aspect of reproductive care. We explore what options are available for fertility preservation, including egg and sperm freezing, and why it's so important to initiate these discussions before starting chemotherapy or radiation. Dr. Jain also explains the difference between Letrozole and Clomid, the impact of estrogen-sensitive cancers on IVF treatments, and innovative approaches like random-start cycles and DuoStim protocols. Whether you're facing a cancer diagnosis or simply thinking proactively about your reproductive future, this conversation is filled with knowledge and reassurance. Key Takeaways: Why it's essential to discuss fertility before starting cancer treatment. The role of Letrozole in estrogen-sensitive cancers and fertility preservation. Differences between Letrozole and Clomid, and why Letrozole is often preferred. How new protocols like DuoStim and random-start cycles are improving outcomes. Why fertility preservation is important even for those without a cancer diagnosis. Guest Bio: Dr. Nirali Jain (@eggspert_md) is a board-certified OB/GYN and fertility specialist at Reproductive Medicine Associates (RMA) in Basking Ridge, New Jersey. She earned both her undergraduate degree in neurobiology (with a minor in dance!) and her medical degree from Northwestern University, before completing her residency at Weill Cornell/NYP, where she served as co-Chief Resident, and her fellowship in reproductive endocrinology and infertility at NYU Langone. Deeply passionate about women's health and fertility preservation, Dr. Jain blends the latest research and cutting-edge treatments with compassionate, patient-centered care. Her interests include third-party reproduction and oncofertility, and she is especially passionate about supporting patients navigating fertility preservation through a cancer diagnosis. Outside of the clinic, Dr. Jain is a trained dancer, a dedicated global traveler, and an adventurer working toward hiking all seven continents with her husband. Her diverse experiences, from international medical rotations to personal connections with friends and family navigating infertility, have shaped her into a warm, resourceful, and determined advocate for her patients. Links and Resources: Visit RMA websiteFollow Dr. Nirali Jain on Instagram For more information about Michelle, visit www.michelleoravitz.com To learn more about ancient wisdom and fertility, you can get Michelle's book at: https://www.michelleoravitz.com/thewayoffertility The Wholesome Fertility facebook group is where you can find free resources and support: https://www.facebook.com/groups/2149554308396504/ Instagram: @thewholesomelotusfertility Facebook: https://www.facebook.com/thewholesomelotus/ Disclaimer: The information shared on this podcast is for educational and informational purposes only and is not intended as medical advice. Please consult with your healthcare provider before making any changes to your health or fertility care. -- Transcript: # TWF-Jain-Nirali (Video) [00:00:00] **Michelle Oravitz:** Welcome to the podcast Jain. **Dr. Nirali Jain:** Thanks so much for having me **Michelle Oravitz:** Yeah, so. **Michelle Oravitz:** I'm very excited to talk about this topic, which, um, actually you don't really hear a lot of people talking about, which is how to preserve your fertility if you're going through a cancer diagnosis and if you have to go through treatments. 'cause obviously that can impact a lot on fertility. **Michelle Oravitz:** I have, um, seen actually like a colleague of mine go through. And she also preserved her fertility and, and now she has a baby boy. so it's really nice. **Michelle Oravitz:** to **riverside_nirali_jain_raw-video-cfr_michelle_oravitz's _0181:** so nice. **Michelle Oravitz:** So I'd love for you first to introduce yourself and kind Of give us a background on how you got into this work. **Dr. Nirali Jain:** Of course. Um, so I am Dr. Narly Jane. I am, um, an OB GYN by training, and then I did an additional, after completing four years of residency in OB GYN and getting board certified in that, I did an additional training in reproductive endocrinology and [00:01:00] infertility or otherwise known as REI. So now I'm a fertility specialist. **Dr. Nirali Jain:** Um, I trained at Northwestern in Chicago, so I went to undergrad and medical school there. And then, um, home has always been New Jersey for me, so I moved back out east to New Jersey. Um, I did all my training actually in New York City at Cornell for residency and NYU for fellowship. Um, and then moved to the suburbs. **Dr. Nirali Jain:** Um, and now I'm a fertility specialist in, in Basking Ridge at Reproductive Medical Associates. **Michelle Oravitz:** Very impressive background. That's awesome. **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** I'd love to hear just really. About what your process is. If a person has been diagnosed with cancer, like what is the process? What are some of the things that you address if they are trying to preserve fertility, and what are some of the concerns going **Dr. Nirali Jain:** yeah, yeah. All great questions. So, you know, there's a lot of us, uh, the Reis. Are a very small, [00:02:00] there's a very small number of us. So in terms of specializing in fertility preservation, technically we all are certified to treat patients with cancer and kind of move them through fertility preservation before starting chemotherapy. **Michelle Oravitz:** Mm-hmm. **Dr. Nirali Jain:** Um, luckily we've been working closely with oncologists in the past several years just to establish some type of streamlined system because having a diagnosis of cancer and hearing all that information. Especially when you're young is so hard. So I think that's, that's where my interest started in terms of being able to speak to and counsel cancer patients. **Dr. Nirali Jain:** I think it is a very specific niche that you really have to be comfortable with in our field. Um, I. So I'll kind of walk you through, you know, what it, what does it look like, right? Um, you go into your oncologist's office suspecting that you have this, this lump. I'll take breast cancer, for example. It could really be any kind of cancer. **Dr. Nirali Jain:** Um, but breast cancer in a reproductive age patient or someone that's in those years where you're starting [00:03:00] to think about building a family, planning a family, um, or if you have kids at home, that's usually the type of patient that we see come in with a breast cancer diagnosis. So. Kinda just taking that, for example, um, the minute that you're diagnosed, it's really your oncologist's responsibility to counsel you on what treatment options are going to be offered to you. **Dr. Nirali Jain:** And then based off of the treatment options, it's important to know how that affects your reproduction. So how does it affect your ovaries in the short term, in the long term, um, in any way possible. So. Once a patient is initially referred from their oncologist to myself or any other fertility specialist, they come into my office and we just have a 30 minute conversation really talking about family planning goals. **Dr. Nirali Jain:** Any kids that they've had in the past either naturally conceived or through um, IVF, and then we talk about where they're at in their relationship. Are they married, are they not? Are they with a partner, [00:04:00] a male partner, a female partner, whatever it might be. It's important to know the social standpoint, um, especially in this sensitive phase of life. **Dr. Nirali Jain:** So patient patients usually spend anywhere from 30 minutes to an hour. Um, just kind of talking through where they're at, how they're feeling, what their ultimate childbearing goals are. And then from there we do an ultrasound and that's when I'm really able to see, you know, the, the reproductive status. **Dr. Nirali Jain:** So what do the ovaries look like? What does the uterus look like? Is there something that I need to be concerned about from a baseline GYN standpoint? Um, and all of those conversations are happening in real time. So. I think one of the things is patients come in and they're like, I'm already so overwhelmed with all this information from my oncologist, and now my fertility specialist is throwing all this information at me. **Dr. Nirali Jain:** Luckily, the way I like to frame it is you come in and you just let go. Like you let us do the work because in the background we're the ones talking to your oncologist. We're the [00:05:00] ones giving that feedback and creating a timeline with your oncologist. Um, and really I think just getting in the door is the hardest part. **Dr. Nirali Jain:** So once patients are here to see us, we go through the whole workup. We do anything that we would do for a normal patient that came in for fertility preservation. And then based off of where they're at in their journey, we talk about what makes sense for them, whether that means freezing embryos, freezing eggs, they're very similar in terms of the, the few weeks leading up to the egg retrievals. **Dr. Nirali Jain:** So I have that whole conversation just at the initial visit. And then from there we talk about the timeline behind the scenes and make sure that it works with their lives before moving forward. **Michelle Oravitz:** So for people listening to this, why, and this might be an obvious question, but to some it might not be, **Dr. Nirali Jain:** Mm-hmm. **Michelle Oravitz:** why would somebody want to preserve. eggs or sperm. 'cause I've had actually some couples **Dr. Nirali Jain:** Yep. **Michelle Oravitz:** come to me where the husband preserved the sperm and they had to go through IVF just because he was going [00:06:00] through cancer treatments. So he had to preserve the sperm ahead of time. **Dr. Nirali Jain:** Mm-hmm. **Michelle Oravitz:** people need to consider doing that before doing cancer treatments? **Dr. Nirali Jain:** So there are certain cancer treatments that do affect the ovaries and the sperm health, and you know, for men and women, it affects your reproductive organs. In a similar way, um, depending on the type of chemotherapeutic agent, there are some that are more dangerous in terms of, um, being toxic to your ovaries or toxic to your sperm. **Dr. Nirali Jain:** And those are the instances where we are really thinking about what's the long-term impact because there's medications that oncologists do give patients, and our oncologists are amazing, the ones that we work with, Memorial Sloan Kettering from Reproductive Medical Associates through RMA, um, and. **Dr. Nirali Jain:** They're just so good at what they do and are so well-trained, so they know in the back of their mind, is this going to impact your ovaries or your sperm health or not? Um, and I [00:07:00] think that any chemotherapy, you know, your ovaries are these, these small organs that are constantly turning over follicles every month. **Dr. Nirali Jain:** So every month we're losing those eggs, and if they don't become. If an egg isn't ovulated, it doesn't become a baby, it's just gonna die off. So I counsel even patients that don't have cancer, I counsel them on fertility preservation as young as possible. You know, between the ages of 28 and 35, that's like the best time to preserve your fertility. **Dr. Nirali Jain:** So in cancer patients, there's an extra level added to that where even if they are a little bit younger, a little bit older. Your eggs are not gonna be the same quality. There's gonna be higher level of chromosomal errors, more DNA breakage, um, and, and bigger issues that lead to issues with conceiving naturally afterwards. **Dr. Nirali Jain:** So I think that it's important to consider how that chemotherapy is going to affect them or how surgery would affect them if it was, for example, a GYN cancer where [00:08:00] we're removing a whole ovary, you know, what, what do we have to do to preserve your fertility in that case? And those are important conversations to have. **Michelle Oravitz:** Yeah. for sure. I know that a lot of people are also concerned, you know, with going through the IVF process, you're taking in a lot of estrogen, a lot of hormones, and many cancers are actually estrogen sensitive. So I wanted to talk to you about that. 'cause I know that the data shows that it's. It's been fine, which some people might find surprising, but I wanted you to address that and just kind of **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** from your perspective. **Dr. Nirali Jain:** That's so interesting that you asked that question because I actually, my whole I I graduated fellowship last year and my entire, like passion project in fellowship was looking at one of the drugs that we use to suppress the estrogen levels specifically in cancer patients. Um, and I had presented this at a few of our reproductive meetings. **Dr. Nirali Jain:** Um, A SRM is one of our annual meetings where all of the reiss get together. A lot of male fertility [00:09:00] specialists come and we kinda just talk about. Specific things and fertility preservation for cancer patients is, has been an ongoing topic of interest for all of us. Um, and it's important to know that there are different medications that we can offer. **Dr. Nirali Jain:** Letrozole is the one that I, um, have a particular love for and I, uh, you know, I use all the time for my patients, um, for different reasons, but it suppresses the exposure that your body has to estrogen. And there's mixed data, um, out there in terms of, you know, does Letrozole suppression actually impact, you know, does it help or. **Dr. Nirali Jain:** Or does it have no impact on your future risk of cancer after treatment? Um, and that honestly is still up for debate. But what we do know is that there's no increased risk of cancer recurrence in patients that have undergone fertility preservation with or without Letrozole. Um, Letrozole is one of those things that we can give, and the way it works is basically. **Dr. Nirali Jain:** It masks that [00:10:00] conversion. It, it doesn't allow for conversion from those androgens in the male hormones over to estrogen. Um, and so your body doesn't really see that estrogen exposure. It stays nice and low throughout your cycle, and it does help with actually ovarian maturation and getting mature eggs harvested and, um, helps a little bit with, with quality too. **Dr. Nirali Jain:** So I think that it's really nice in terms of having that available to us, but know that. It's not, it's not essential that you have it, really, the data showing plus minus. Um, but there are certain things that we can do to protect the ovaries, protect your exposure to estrogen. Um, and so that shouldn't be top of mind of concern when we're going through fertility preservation, even with an estrogen sensitive cancer. **Michelle Oravitz:** Actually, so, uh, on a different topic, kind of going back to that, so Letrozole versus Clomid, I, it's like a, the questions I personally feel just based on what I've heard and like my own research that Letrozole would be kind of like the more. [00:11:00] Um, the, it's, it's a little better, but I know that it really depends on the person as well. **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** they might do better with Clom, but I'd love to hear your perspective and kind of pick your brain on this. **Dr. Nirali Jain:** totally. You're choosing all the, all the right questions because these are all of my, my specific interests and niches. So **Michelle Oravitz:** Oh, **Dr. Nirali Jain:** Letrozole is basically, you know, we use Letrozole and Clomid in. Patients that don't have cancer and patients that come in for an intrauterine insemination, that's kind of the most common scenario where we're thinking about, you know, which medication is better? **Dr. Nirali Jain:** Letrozole or Clomid and Clomid used to be the, the most common medication that we use, we dose patients, you know, have 50 milligrams of Clomid, give them five days of the medication. It's an oral pill. Feels really easy and. The way it works is really, it recruits more than one follicle, so it really helps with the release of, um, more than one follicle growing more than one follicle in the ovary. **Dr. Nirali Jain:** Um, but it has a little bit [00:12:00] higher of a risk of twins because that's exactly what it's good at. Um, Clomid, not so much in the cancer. In the cancer front, it's not really used there because it's considered, from a scientific perspective, it's considered like a selective estrogen receptor modulator. So it doesn't necessarily suppress your estrogen levels in the same way that Letrozole does versus. **Dr. Nirali Jain:** Letrozole is an aromatase inhibitor, so it really blocks the chemical conversion of one drug or one hormone to the other hormone. Um, the reason we love Letrozole so much, and I don't mean to like gush over Letrozole, but um, it's a mono follicular agent, so it works really well at recruiting one follicle **Michelle Oravitz:** Mm-hmm. **Dr. Nirali Jain:** you know, every OB-GYN's nightmare in a way is having multiples when you didn't intend on having multiples at all. **Michelle Oravitz:** so **Dr. Nirali Jain:** Um. **Michelle Oravitz:** were saying that, um, there's more of a chance of twins, it's Clomid, not letrozole. **Dr. Nirali Jain:** Yes, there's a higher chance with Clomid versus Letrozole. And I mean, don't get me wrong, there's a chance of twins with [00:13:00] any type of assisted reproductive technology. Even when we're doing single embryo transfers, there's a chance that it's gonna split. So, um, the chance is always there just like it is in the natural world. **Dr. Nirali Jain:** But we know for a fact that. CLO is really good at recruiting many follicles. It's good for certain patients that don't respond well to Letrozole. Um, but Letrozole is kind of our, our go-to drug these days just because of all the benefits that we've seen. **Michelle Oravitz:** Awesome. **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** These are all fun things to ask because I, I love talking to our eis 'cause there's so much information that I'm always **Dr. Nirali Jain:** totally. **Michelle Oravitz:** learn a lot from my patients in my own research, but it's really cool. Picking your guys' brains. So another question I have, and I have actually talked to Dr. Andrea Elli, he's been on, **Dr. Nirali Jain:** Mm-hmm. **Michelle Oravitz:** and he does a lot of endometriosis and, and immune related work as well, **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** so. I'd love to know just from your perspective. One thing that I do know from, based on what I've heard is that the, [00:14:00] guess like you were just saying, that breast cancer or estrogen sensitive breast cancer doesn't seem to be affected by IVF cycles, however, and endometriosis lesions do get affected. **Dr. Nirali Jain:** Yeah. **Dr. Nirali Jain:** that's a great question. So, you know, every, there are so many complex G mind diagnoses that the, that our patients come in with. Um, and endometriosis is a big one because there is clear data that endometriosis is linked to infertility. So we think about, you know, when a patient comes in with endometriosis, we really do think about the different treatment options and what are the short-term and long-term impacts of the hormones that we're giving 'em. **Dr. Nirali Jain:** Um, these days, again, kind of going back to Letrozole, we, letrozole is something that I give all of my endometriosis patients because it helps suppress their estrogen because we know. **Michelle Oravitz:** interesting. **Dr. Nirali Jain:** is very responsive to estrogen and leads to this dysfunctional regulation of all the endometrial tissue that can really flare in a, [00:15:00] in a cycle, or shortly after a cycle. **Dr. Nirali Jain:** I. So we really, for endometriosis patients, the, the best treatment is being on birth control because we don't see that hormonal fluctuation. The up and down of the estrogen and the progesterone, that's what leads to those flares. Um, so I really, I watch patients closely after their cycles too, because you definitely can have an endometriosis flare and we say the best treatment for endometriosis is pregnancy, right? **Dr. Nirali Jain:** That's when you're suppressed, that's when you're at your lowest. Um, and patients, my endo patients feel so good in pregnancy because they have. Hormones that are nice in that baseline, they're not getting periods of course. Um, and that's truly, truly the best treatment. **Michelle Oravitz:** That's interesting. **Dr. Nirali Jain:** But it is important to consider when you're going through infertility treatments. **Dr. Nirali Jain:** How does my endometriosis affect the short and long-term effects of the fertility medications? And really not to, not to say that they're bad in any way. I think a lot of endometriosis patients go through IVF and have success and do really, really well, and that's kind of the push that they need. [00:16:00] Um, but it's important to be mindful of the bigger picture here. **Dr. Nirali Jain:** It's not just, you're not just a number of. A patient with endo coming in, getting the same protocol. It's really individualized to the extent of your lesions, what symptoms you're having, what grade of endometriosis, where your lesions are. So we're the RAs are thinking about everything before we actually start your protocol. **Michelle Oravitz:** It's crazy how in depth it is, and it's, it, there's just so, it's so multifaceted, **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** when it's females **Dr. Nirali Jain:** totally. **Michelle Oravitz:** are a little, I mean, they can, you know, there, there's definitely a number of things, but it's not as complicated and interconnected **Dr. Nirali Jain:** Exactly. Exactly. That's so true. **Michelle Oravitz:** And so one question I actually have, this is kind of really off topic, but something that I was curious about. **Michelle Oravitz:** 'cause I heard about a while **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** a, a type of cancer treatment that was used. I'm not sure exactly what it was, but for some reason it actually caused follicles to grow, [00:17:00] or to multiply. And they were **Dr. Nirali Jain:** Interesting. **Michelle Oravitz:** this definitely. Puts, um, the whole idea of like a woman being born with all the follicles she'll ever have on its head, I thought that was really Interesting. **Michelle Oravitz:** Now I learned a little bit about it. I don't think it really went further than that, **Dr. Nirali Jain:** Mm-hmm. **Michelle Oravitz:** one of those things that they're like, Hmm, this is interesting. I don't know, it was kind of a random side effect of this chemo drug. I dunno if it was a chemo drug or a cancer drug. **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** ever heard of that. **Michelle Oravitz:** So I was just **Dr. Nirali Jain:** I haven't, I mean, that's interesting. I feel like I'd have to look into that because that would be definitely a point of interest for a lot of Reis. But it kind of does go back to the point of, you know, women are really born with all the eggs we're ever gonna have. So it's about a million, and then it just goes down from there. **Dr. Nirali Jain:** And the, by the time you start having periods, I like to kind of show my patients a chart, but you have a couple hundred thousand eggs and you ovulate one egg a month. That's, you know. Able to [00:18:00] progress into a fertilized egg and then into a, an embryo into a baby, um, if that's your goal. But otherwise, patients that are having periods and not trying to actually get pregnant, we're losing hundreds of eggs a month. **Dr. Nirali Jain:** So. **Michelle Oravitz:** Mm. **Dr. Nirali Jain:** It's important to kind of think about that decline, and it's important to know that that rate can be faster in patients with cancer, patients with low ovarian reserve. And sometimes when you have the two compounded, that's when a fertility specialist is definitely, you know, in the queue to, to have a discussion with you in terms of what that means and how you can reach your family building goals despite being faced with that, with that challenge. **Michelle Oravitz:** Yeah. **Michelle Oravitz:** I mean, 'cause we know oxidative stress is one of the things that can cause, uh, **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** quality eggs, but it's also can cause cancer. **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** um, similar, you know, like things that really deplete the body could definitely impact. Um, and then what are your thoughts? I know I'm asking you all kinds of random questions, **Dr. Nirali Jain:** I love it. **Michelle Oravitz:** are your thoughts about doing low simulation in certain [00:19:00] circumstances versus high stem? **Michelle Oravitz:** Sometimes people don't respond as well to higher stems. **Dr. Nirali Jain:** Yeah, that's a great point. I think that it kind of all goes back to creating an individualized protocol. If. A patient's going to a practice and basically just getting a protocol saying, this is our standard. We start with our standard of, you know, I, I think about the standard, which is 300 of the FSH or that pen that you dial up, and then 150 units of that powder vial. **Dr. Nirali Jain:** And we have patients mixing powders all the time, and that's kind of our blanket protocol that we give patients. But that's not really what's happening behind the scenes. And if you're given a protocol that's, and being told, you know, this is kind of what we give to everyone, it's probably not the right fit for you. **Michelle Oravitz:** Yeah, I **Dr. Nirali Jain:** Um, there are certain patients that respond to a much lower dose and do really, really well, and then some patients that need a much higher dose. Um, and I think it's, that's kind of like the fun part of being an REI of being able to individualize the [00:20:00] protocol to the patient. Um, and I know for a fact there are so many, luckily, you know, we have so many leaders in REI that have been. **Dr. Nirali Jain:** Have dedicated their entire careers to researching these different protocols and how they can help different patients. Um, patients with lower a MH, you know, might benefit from a duo stim protocol, for example. That's kind of the first one that comes to mind, but a protocol where we're using those follicles from the second half of a cycle. **Dr. Nirali Jain:** I would've never thought that those were the follicles that **Michelle Oravitz:** Oh, **Dr. Nirali Jain:** would be better than the first half of the cycle, **Michelle Oravitz:** Wait, **Dr. Nirali Jain:** but, **Michelle Oravitz:** that. Explain that. Um, because I think that that's kind of a unique **Dr. Nirali Jain:** mm-hmm. **Michelle Oravitz:** that I haven't heard of. **Dr. Nirali Jain:** Yeah, so there's this new day. It's still kind of developing, but um, kind of going back to, you know, what's an individualized protocol? Duo STEM is one of the newer protocols that we've started using. I, I've used it once or twice in patients. Um, but it goes back to the research that shows that you might actually have two different periods of time in a menstrual cycle where you could potentially recruit [00:21:00] follicles. **Dr. Nirali Jain:** You could have a follicular phase where there's a certain cohort of follicles recruited, and then you have a follicle that forms creates a corpus glut. **Michelle Oravitz:** um, protocols **Dr. Nirali Jain:** Yep. And then you basically go through the follicular protocol and then a few days after a retrieval, instead of waiting for a new follicular cohort or follicular recruitment from the first half of your menstrual cycle, you actually use the luteal phase and you recruit those follicles that would've actually died off or have been prematurely recruited in a prior cycle. **Dr. Nirali Jain:** So **Michelle Oravitz:** that's So **Dr. Nirali Jain:** yeah, **Michelle Oravitz:** you just do a similar, I guess, um, medicine, **Dr. Nirali Jain:** go right back into it. **Michelle Oravitz:** do the same exact thing, but right after ovulation. **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** Fascinating. That's really interesting. **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** has been your experience with that? **Dr. Nirali Jain:** I think it's, honestly, it's mixed. Um, so far, you know, our data from fertility and sterility and A SRM, it, it shows support for these DUO STEM [00:22:00] protocols, saying that if patients don't have that great quality of eggs or if they have a very low number, maybe they'd benefit from starting the meds earlier and recruiting follicles. **Dr. Nirali Jain:** A little bit earlier. Um, so we've seen positive results so far. A lot of work to be done in terms of really understanding it. Um, and of course, as a new attending, I have a lot more experience to kind of build on. Um, but I, I have seen success from it. **Michelle Oravitz:** That's fascinating. Are there any other new technologies, like new add-ons, um, that you've seen, that you've found to be really cool or interesting? **Dr. Nirali Jain:** I think the biggest thing, actually, kind of going back to our whole topic for today is fertility preservation cancer patients. One of the biggest things that I've learned recently is that we used to start fertility, um, patients. You know, only in the beginning of the cycle days, two or three is technically like when most. **Dr. Nirali Jain:** Most clinics, um, start patients, but for our cancer patients, sometimes you don't have that time. You don't wanna wait a full month to [00:23:00] restart, um, your, you know, your menstrual cycle and then do the fertility preservation and then delay chemotherapy a full month. So we started doing what we call random starts. **Dr. Nirali Jain:** So you basically start a patient whenever they come in. You know, it could be the day after your consultation, the day of your consultation. I've kind of seen all of the above. Um, and we've seen really good success with random starts, per se. Um, and we've been doing a lot more of that, where it's not as dependent on where you're at in your cycle. **Michelle Oravitz:** Mm-hmm. **Dr. Nirali Jain:** Um, obviously there's a difference in outcomes. You might not be a great candidate for it, so definitely it's worth talking to your doctor about it. But it kind of gives relief to our cancer patients where if you have a new cancer diagnosis and you're like, oh, I just finished my period, like, I can't even start a cycle until next month. **Dr. Nirali Jain:** That's not always true. Um, so it's always worth it to go into see a fertility specialist and just get, you know, get the data that you need right away, and then you can make a decision later on. **Michelle Oravitz:** For sure. Um, Yeah. **Michelle Oravitz:** and I wanted to kind of cover a lot of different topics 'cause I know that [00:24:00] some people are gonna wanna hear what you have to say that don't necessarily, or, uh, have cancer. But it is important. I, I think that, you know, if you get to thirties and you haven't gotten married or you don't have a partner, I think it's really important to preserve your fertility in general. **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** important thing. And then if you were going through a cancer diagnosis and you decided to preserve your fertility, um, guess more for women because they're eventually going to be thinking about transfers after they go through treatment. So what are some of the things that they would need to consider as far as that goes? **Michelle Oravitz:** Like after the **Dr. Nirali Jain:** yeah, **Michelle Oravitz:** then they go through the cancer treatments. Um, and then what, how long should they **Dr. Nirali Jain:** yeah. Like what does it look like? So I've had patients that come back, you know, in my fellowship training I did a, a couple research projects on patients that came back to pursue an embryo transfer, um, after chemotherapy agent. And basically compared them to how they did, um, [00:25:00] compared to patients that didn't have cancer and just froze their embryos or froze their eggs and then came back to pursue a transfer and. **Dr. Nirali Jain:** I think the, the most reassuring thing from the preliminary data that we have is saying that there's no difference in pregnancy rates and no difference in life birth, **Michelle Oravitz:** Awesome. **Dr. Nirali Jain:** of whether they had chemotherapy or not. After freezing those eggs and going through fertility preservation. **Michelle Oravitz:** Amazing. **Dr. Nirali Jain:** Um, in terms of where your body needs to be, I think the oncologist, we, we wait for their green light. **Dr. Nirali Jain:** We wait for their signal to say, you know, she's safe to carry a pregnancy. **Michelle Oravitz:** Mm-hmm. **Dr. Nirali Jain:** And then once we do that, we basically treat you like any other patient. So if you're coming in for a cycle, if you're having periods, then it's reasonable to try a natural cycle protocol, wait for your body to naturally ovulate an egg. **Dr. Nirali Jain:** And instead of obviously hoping that egg will fertilize, we, um, use a corpus luteum. We use the progesterone from the corpus luteum to really support this embryo being implanted into the uterus. Um. Yeah. [00:26:00] And then there's also another side. I mean, some patients don't get their periods back and they always ask like, what if I never get my period back? **Dr. Nirali Jain:** What if I'm just like in menopause because of the chemotherapy agents? And for that, we can start you on a synthetic protocol or basically an estrogen dependent protocol where you take an estrogen pill for a certain number of days. We monitor your lining, then we start progesterone, um, to support your hormones from that perspective instead of relying on your ovaries to release the progesterone that they need, um, and then doing the embryo transfer a few, few days after progesterone starts. **Dr. Nirali Jain:** So there's definitely different protocols depending on where your menstrual health is at after the chemotherapy or after the cancer treatment. Um, but it's important to kind of just know that. That there's options. It doesn't mean that it's the end of the road if you all of a sudden stop getting your period. **Michelle Oravitz:** Yeah, for sure. I mean, 'cause you, technically speaking, you can really control a lot of that. More so for transfers **Dr. Nirali Jain:** Yep. **Michelle Oravitz:** Retrievals really is kind of like what [00:27:00] eggs you have, what the quality is. But people can be in complete menopause and you guys can still control their cycles for transfer, which is kind of. A huge difference **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** in the **Dr. Nirali Jain:** exactly. That's exactly right. Yeah. **Michelle Oravitz:** interesting. Any other, um, new, new things that you're, you guys are excited about? I always like to hear about like the new and upcoming things **Dr. Nirali Jain:** Of course. **Michelle Oravitz:** actually before, which I thought was fascinating. Yeah. **Dr. Nirali Jain:** I feel like there's always like updates and, and new data and things like that coming out, but just know, I think it's important for patients to know, like we're constantly, we're, the reason I chose to even pursue this field was because it's new. Right. There's something that we are discovering every day, every year, and that's what makes our, our conferences so important to attend, um, to really just stay up to date. **Dr. Nirali Jain:** Um, but we are, uh, constantly updating our embryology standards, the way we thaw our eggs, and the success rate associated with a thaw and [00:28:00] how we treat our embryos and the media that we use, right? Like, so we're really thinking about the basic science perspective every single day, and that's what makes this field so unique. **Michelle Oravitz:** It is really awesome. And so do you guys specialize specifically on, um. Egg freezing and, and I mean specific fertility preservation in patients that do that have cancer that are going through treatments, do you guys specialize specifically in that? I mean, I know you do range **Dr. Nirali Jain:** Yeah. Yeah, because it's such a small community, we all have our own niches and we all kind of have our own interests and **Michelle Oravitz:** Yeah. **Dr. Nirali Jain:** no like specific training. There are a couple courses that you take that I took in in training as well, just to kind of understand what it sounds like to, I. Council of fertility preservation, patient with and without cancer. **Dr. Nirali Jain:** Um, and then, you know, you kind of just learn by experience and you form a niche for something that you're passionate about. 'cause that's what makes you, you know, really thorough in, in your treatment. [00:29:00] So that's one of my interests. Um, and, but I would say, **Michelle Oravitz:** training for that. It's just like **Dr. Nirali Jain:** yeah, **Michelle Oravitz:** just know how to treat that in **Dr. Nirali Jain:** exactly. **Michelle Oravitz:** especially if you're interested in doing that. **Dr. Nirali Jain:** Exactly. That's exactly right. It's kind of, it just comes with the experience comes with your mentors and who you're surrounded by, and everyone kind of helps each other get to that point. But there are several specialists in our practice at RMA that specialize specifically in fertility preservation in cancer patients. **Dr. Nirali Jain:** So we have a close communication with our oncologist and they know who to refer to within the practice because everyone has their own little interests. **Michelle Oravitz:** Amazing. **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** Um, definitely. I, like I said, I really enjoy picking your brain because it's a lot of fun for me. I, I do **Dr. Nirali Jain:** Totally. **Michelle Oravitz:** acupuncture, so **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** and I, I think that it's just so crazy that our fields don't work together. I mean, we kind of do, but I think, I just feel like it would be so great **Dr. Nirali Jain:** exactly.[00:30:00] **Michelle Oravitz:** the expertise because you guys have immense. Benefits like in, in, uh, technology and incredible innovations and, and then the natural aspect of really understanding the, the body. And I, I just think that it would work so amazing together if it was more of like a thing. 'cause it, I know in China they actually combine the two **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** eastern. **Dr. Nirali Jain:** Yeah, I mean I think that that's so important and there is data that shows, you know, there's actually a recent study that came out just a few weeks ago on the benefits of acupuncture for fertility patients. And we know that, I mean, I recommend it to all of my patients, specifically the day of the embryo transfer. **Dr. Nirali Jain:** We, luckily, we offer it on site at RMA and we have acupuncturists that come in and, and do a session before and after the embryo transfer, and I think. A lot of that is targeted towards stress relief. But I also think that holistically it's important to feel at your best when we're doing something that's so crucial to your, to your health. **Dr. Nirali Jain:** So to really focus on the diet, focus on stress relief, [00:31:00] focus on meditation, yoga, whatever it takes to get to your best wellbeing when you're going through fertility treatments, um, is so important. So I appreciate **Michelle Oravitz:** Mm-hmm. **Dr. Nirali Jain:** like you that really specialize in the other side of. Of this, because I do consider it still part of the holistic medicine that we need to really maximize success for our patients. **Michelle Oravitz:** Awesome. Well, **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** Jane, this is such a pleasure Of talking to you. You've given us some, so much great information and we've definitely dived into a, do a topic that I don't typically, I haven't yet spoken about. But, um, that being said, it's such an important topic to talk about. And thank you so much for coming on today. **Michelle Oravitz:** Oh, **Dr. Nirali Jain:** course. **Michelle Oravitz:** I get off, how can people find you? **Dr. Nirali Jain:** That's a great question. So I have, um, a social media page. I, it's called Expert nc. So like EGG, **Michelle Oravitz:** I **Dr. Nirali Jain:** um, expert nc. Try, tried to make it a little bit humorous. Um, but I'm all over social [00:32:00] media and would love to hear from anyone that is listening. I, you know, every, every day I get different, um, dms and I'm happy to respond. **Dr. Nirali Jain:** I love hearing about everyone else's. Stories and things like that. Um, so that is kind of my main, main social media platform. Um, and then through like RMA and Reproductive Medical Associates, we also have a YouTube channel. We have an Instagram page, um, of our office available, um, as well that is public. **Dr. Nirali Jain:** So you can find us pretty easily if you just kind of hit Google. But um, yeah, I'm kind of developing my social media platform as the expert and I hope it grows. **Michelle Oravitz:** Love it. Great. **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** was such a pleasure talking to you. Thank you. so much **Dr. Nirali Jain:** Thank you. **Michelle Oravitz:** today. **Dr. Nirali Jain:** Of course. Thank you so much for having me. [00:33:00]
In this episode of The Performance Medicine Show, Dr. Rogers answers YOUR health and wellness questions!What did you think of this episode of the podcast? Let us know by leaving a review!Connect with Performance Medicine!Check out our new online vitamin store:https://performancemedicine.net/shop/Sign up for our weekly newsletter: https://performancemedicine.net/doctors-note-sign-up/Facebook: @PMedicineInstagram: @PerformancemedicineTNYouTube: Performance Medicine
Now that Primo is no longer available, will Equipoise be the next go-to steroid to control estrogen? Plus Steroid QA Drugs N Stuff Podcast - Dave Crosland & Scott McNally 0:00 Tren soldiers 0:40 Intro 3:00 Equipoise to control estrogen? 7:00 test conversion vs equipoise conversion 8:15 Test to EQ ratios 9:50 Estrogen and hematocrit 12:30 figuring out how well EQ controls estrogen for YOU 16:10 Prostate Cancer Awareness Event 18:30 Dbol making you feel sick? 21:00 What can you run for joint issues? 24:00 Test & Mast vs Test at same total Mg? 30:45 Removing test and using Dbol for estrogen 33:30 Statin to Control Cholesterol? 37:30 Cycle for Older guy with THREE orals? 39:50 Getting Bloods done at FitExpo 42:45 How important is ester weight 47:25 Minimal amount to cycle? 52:20 Steroid Use and Donating Blood 55:30 Dave's Car Talk 1:03:30 Operator Syndrome and gear in the military
Dr Scott joins the party and shares some interesting studies about HGH Blood Sweat & Gear 301 Coaches Skip Hill, Andrew Berry, Scott McNally 0:00 teaser - Subq vs IM GH Study 1:00 Intro and Welcome Dr Scott Stevenson to the show 2:00 GH IM vs SubQ 5:20 What is GH and what does it do? 8:30 GH Isoforms and Why GH may work better for some than others 11:18 Endogenous vs exogenous GH 15:00 IM vs SubQ HGH 24:30 Estrogen and HGH 26:45 GH is prescribed Subq 30:00 IGF release from HGH 35:00 IGF levels and bodybuilding progress 42:00 Locally produced IGF vs circulating blood levels 46:00 local growth from site specific insulin 52:20 GH and Insulin Timing ? 1:00:00 increlex vs IGFLR3 1:03:00 Skip getting trolled 1:10:30 Pros that never used IGF 1:14:30 Bonus topic : Painful fatty deposits ✅ Signed Copy of Be Your Own Bodybuilding Coach (15% goes to ASPCA) https://www.ebay.com/itm/205121965946
We have covered menopause on this show on various occasions. That's fitting and non-surprising as we are a women's health education podcast! While vaginal dryness and hot flashes get most of the attention in menopause, and they should, less attention often is given to skin changes. Nonetheless, these dermal manifestations of perimenopause and menopause can be just as disturbing to those affected. Estrogen helps skin produce oil and hold onto water, so extremely dry skin during menopause is common. Plus, according to the American Academy of Dermatology, collagen production drops 30% in the first 5 years of menopause and approximately 2% each year for about the next 20 years. Collagen gives skin its plumpness and structure. The direct-to-consumer market is replete with a variety of over-the-counter estrogen containing products, formulated as facial creams, which are meant to fight the battle of skin aging. But is topical estrogen applied to the face effective? What are the data? You'd be surprised to learn that there is published data on this- even level I data. Are there any safety concerns? We will summarize it in this episode. PLUS, as a “two-for one” special, we will also briefly highlight a brand new publication in the journal JAMA Network Open regarding antenatal corticosteroid dose to delivery interval and fetal benefits.
Do you have heavy periods, feel bloated, have headaches, bad PMS, or struggle with infertility and/or fibroids? Have you ever considered that these symptoms—and many more—could be related to a hormone imbalance? Estrogen dominance is one of the most commonly misunderstood hormone issues. In this episode, we take a deep dive into what estrogen dominance actually means. We explore the critical role of your liver and gut in estrogen detoxification and how dysfunction in these systems can lead to symptoms like heavy periods, breast tenderness, anxiety, fatigue, and stubborn weight gain. You'll learn how your liver goes through a two-phase detox process to neutralize estrogen, and how the gut's microbiome—including the estrobolome—can either help or hinder that elimination process. We also unpack a lesser-known but powerful enzyme called beta-glucuronidase, which can cause estrogen that was supposed to be excreted to be reabsorbed back into the body—essentially recycling hormones and contributing to estrogen dominance. This often happens when gut health is compromised due to dysbiosis, constipation, or poor diet. Whether you're in your reproductive years, navigating perimenopause, this episode will help you better understand the physiology behind estrogen dominance and how to begin addressing it at the root. We Heart Nutrition offers high-quality supplements designed specifically for women's health. Here are three standout features: Bioavailable Ingredients: Their supplements use the most absorbable forms of each nutrient, ensuring your body gets what it needs. Third-Party Tested: All products are tested for purity and potency, manufactured in NSF & cGMP certified facilities. Purpose-Driven: 10% of every purchase supports pregnancy care centers, aligning with their pro-life mission. Visit weheartnutrition.com and use code GENIUS for 20% off your first order. Medical disclaimer: The information presented in The Hormone Genius Podcast is for informational purposes only and is not intended to be a substitute for actual medical or mental health advice from a doctor, psychologist, or any other medical or mental health professional.
Ladies, if you've been feeling burnt out, bloated, foggy, or just not yourself — this episode is for YOU.
In this episode, Dr. Heather Rhodes talks about how important it is to make sure your hormones are balanced. Estrogen, Testosterone, and Progesterone are the 3 big driving hormones that we need to be aware of. When those are off then stress and low libido can be a side effect. Dr. Heather walks us through so many practical ways we can help balance our hormones without medication.Dr. Heather was so gracious and opened up her "My Stress Strategy" course just for the LTM community and gave everyone a 35% off discount with the code "LEGACY". The links below are ways you can access Dr. Heather Rhodes post-episode.Your code: https://store.drheatherrhodes.com/stress?coupon=LEGACYMy Website: https://store.drheatherrhodes.com/Instagram: https://www.instagram.com/drheatherrhodes/?hl=enUpcoming Free Webinar: https://www.drheatherrhodes.com/free-webinarDid you know? Stephanie is writing a book! Join the waitlist below!https://stephanie-sims-author.kit.com/765221430e