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Bill George is a celebrated leader who served as Chair and CEO of Medtronic, the world's leading medical technology company. He is an executive fellow at Harvard Business School, where he has taught leadership since 2004, and is the bestselling author of many books, including Discover Your True North. Bill also served as a director at Goldman Sachs, ExxonMobil, Novartis, Target, the Mayo Clinic, and World Economic Forum USA. In this episode of the Elevate Podcast, Bill joins host Robert Glazer to discuss his leadership career, the importance of purpose-driven leadership, and more. To learn more about core values, check out The Compass Within. Thank you to the sponsors of The Elevate Podcast Mizzen & Main: mizzenandmain.com (Promo Code: elevate20) Shopify: shopify.com/elevate Indeed: indeed.com/elevate Masterclass: masterclass.com/elevate Found: found.com/elevate Learn more about your ad choices. Visit megaphone.fm/adchoices
What if everything you thought you knew about cancer treatment was only half the story? In this episode of The Wellness Fix, part of The Brian Nichols Show, we uncover a jaw-dropping first-hand account that challenges the very core of “accepted” medical practice. Imagine being told at 24 years old to get your affairs in order — and then walking away, not only alive but thriving fifty years later. That's the reality of today's guest, Rick Hill. Studio Sponsor: Cardio Miracle - "Unlock the secret to a healthier heart, increased energy levels, and transform your cardiovascular fitness like never before.": CardioMiracle.com/TBNS Rick takes us back to 1974 when the Mayo Clinic delivered a terminal cancer diagnosis and offered only chemotherapy and radiation as options. Facing death, Rick received an unexpected letter that urged him to look beyond the standard treatments. What followed was a radical journey that led him across the border into Mexico — and into a new world of nutrition, natural therapies, and faith-driven resilience. This episode dives deep into Rick's recovery and the controversial role of natural compounds like B17, enzymes, and oxygen therapies. His story highlights the power of alternative approaches, not as quick fixes, but as long-term strategies rooted in God-given natural resources. Along the way, Rick exposes how big medicine often suppresses inexpensive, effective solutions to protect its bottom line. But this isn't just a story of survival. It's about trust, skepticism, and the importance of asking questions when the “experts” say there are no answers left. Brian presses Rick with the kind of skeptical questions you're probably thinking yourself: Why isn't this replicated everywhere? What about the risks? Why the pushback from doctors and regulators? The result is an honest conversation that doesn't shy away from the tension between hope and evidence. By the end, you'll be left with more than just inspiration. You'll gain practical resources, like access to Rick's book and the free download of World Without Cancer. Most importantly, you'll walk away with the reminder that hope is real, choices exist, and sometimes the greatest breakthroughs come when you're willing to think for yourself. Don't miss this powerful episode — your perspective on health may never be the same again. ❤️ Order Cardio Miracle (CardioMiracle.com/TBNS) for 15% off and take a step towards better heart health and overall well-being!
In this episode, I'm talking with Medha Kaul a research data analyst in the Division of Epidemiology at Mayo Clinic about her job and the research she is doing!
In this episode of Tech It To The Limit, hosts Sarah Harper and Elliot Wilson revisit generational myths in digital health and reveal why age isn't the real barrier to adoption. Through their new game, Fact Check Fever, and a deep dive into the Capability-Motivation-Context (CMC) framework, they show how design, usability, and trust matter far more than birth year. From busting stereotypes to exploring how health systems can design with users, not for them, it's a witty, insightful look at the future of inclusive, human-centered innovation.Key TakeawaysGenerational myths don't hold up: Boomers use portals, Gen Z cares about privacy, and every group struggles with clunky design, not just “digital natives.”Design trumps demographics: Adoption isn't about age, it's about usability, accessibility, and human-centered design.Follow the CMC framework: Capability, motivation, and context, not birth year, to predict whether people engage with health tech.Health equity requires intention: Neutral AI does not exist; equity has to be actively built into technology.The biggest unifier isn't age: A diagnosis, condition, or shared health journey brings people together across generations more than labels like Boomer or Gen Z.In this episode:[00:00:13] Welcome & episode introduction[00:00:55] Recap of Mayo Clinic live show[00:02:36] Looking ahead to HLTH: speakers, tracks, and the health tech “fashion week” vibe[00:05:08] Conference tracks & awards00:07:13] Launching Fact Check Fever: busting myths on portals, EHR burnout, Gen Z TikTok habits, and more[00:07:37] Fact Check Fever: generational myths & data[00:19:24] Break for fake sponsor: Patient Portal Plus Plus[00:20:44] Sincere segment: CMC framework for health tech adoption[00:22:24] Deep dive: CMC framework explained[00:31:17] Designing with, not for, users[00:35:31] Break for fake sponsor: Bias Focals[00:37:14] Spicy Nugs: co-host lightning round[00:46:41] Closing thoughts, HLTH call-to-action, and Elliot's health tech haikuResourcesTech It To The Limit PodcastWebsite Apple PodcastSarah HarperLinkedIn -https://www.linkedin.com/in/sarahbethharperElliott WilsonLinkedIn - https://www.linkedin.com/in/matthewelliottwilson
Published October 2, 2025 In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, and Elitza Theel, Ph.D., director of the Infectious Diseases Serology Laboratory at Mayo Clinic, discuss the latest developments in self-collection testing for women's health and beyond. Together, they explore:New podcast format launching (00:01): Dr. Pritt previews exciting changes coming to “Answers From the Lab.” Emerging self-collection tests (01:21): Explore the growing range of self-collection tests now available for use in both clinical settings and at home.Validation of self-collection tests (03:19): Learn how laboratorians validated recent self- and home-collection tests to ensure quality and accuracy. Benefits for patients and public health (06:56): Understand the benefits self-collection tests offer to patients and how the tests impact public health.Limitations and implementation considerations (08:23): Review key factors to consider when incorporating self-collection testing into clinical care.Future innovation (11:34): Insights into where self-collection testing may evolve in the years ahead.
This week marks the 10th anniversary of the Kahn Center for Cardiac Longevity—thank you for being part of the journey! Dr. Kahn reviews important new Mayo Clinic data comparing causes of heart attacks in men vs. women under 65. The findings show that non-traditional causes are significantly more common in women. Because the study ended in 2018, neither COVID nor vaccine-related data were included. In addition, Dr. Kahn covers a range of timely health topics: Sucralose (Splenda) and cancer therapy Magnesium for hypertension Eating early vs. late in the day Hydration and survival The ongoing debate over whether meat promotes or protects against cancer deaths (spoiler: it does not) Thanks to Igennus.com—use discount code DrKahn for savings. And don't miss the group PROLON fast beginning October 5, 2025. Order your kit now at prolonlife.com/drkahn.
Start Living Sustainable | Wellness Coach, How to Live Toxic Free for Health-Conscious Women
Heart attacks aren't just an older generation's issue anymore. A new Mayo Clinic study shows that 1 in 10 heart attacks in women under 40 are linked to stress, anemia, overexercising, and postpartum recovery — not clogged arteries. In this episode, Coach Cynthia explains these hidden risks and how moms can protect their heart health, reclaim energy, and create a calmer, healthier home.
When radiology meets surgery, endometriosis care becomes more precise, personalized, and proactive. In this BackTable OBGYN Brief, host Dr. Mark Hoffman is joined by Dr. Wendaline VanBuren, an associate professor of radiology at Mayo Clinic, and Dr. Tatnai Burnett, a minimally invasive GYN surgeon at Mayo Clinic, to discuss the complexities of diagnosing and managing endometriosis. The discussion covers the roles of advanced imaging techniques like MRI and ultrasound, the importance of pre-surgical planning, and the need for multidisciplinary collaboration. They share their approach to managing symptomatic and asymptomatic patients, the use of hormonal treatments, and the significance of monitoring potential malignant transformations in endometrioma cases. The episode underscores the critical role of imaging in planning effective surgical interventions for patients while highlighting the progression of endometriosis management protocols. TIMESTAMPS 00:00 - Introduction 01:07 - Discussing Endometriosis Management 02:18 - Imaging Techniques and Their Importance 04:24 - Interdisciplinary Collaboration 05:40 - Advanced Imaging Protocols 08:12 - Monitoring and Follow-Up Strategies 08:50 - Concerns About Malignancy 11:04 - Future Directions CHECK OUT THE FULL EPISODE OBGYN Ep. 69 https://www.backtable.com/shows/obgyn/podcasts/69/imaging-protocols-to-guide-endometriosis-treatment
Welcome to Ozempic Weightloss Unlocked, where we dive into the latest breakthroughs and controversies surrounding Ozempic, its medical use, and its impact on everyday wellness.The big headline this month is the arrival of a new pill form of semaglutide, the main ingredient in Ozempic. According to The New England Journal of Medicine, people who took this daily pill lost almost 14 percent of their body weight over 64 weeks, compared to just 2 percent for those on a placebo. Fifty percent of the patients shed at least 15 percent of their weight, with nearly a third losing 20 percent or more. Novo Nordisk, the company that makes Ozempic, announced even stronger results for those who stuck to their treatment plan, with close to 17 percent average weight loss. This pill, pending approval, could be a game changer for people who prefer not to take injections.On the injectable front, clinical trials featured in The Lancet indicate that a higher 7.2 milligram weekly dose of semaglutide in adults without diabetes led to almost 19 percent average weight loss, higher than what's seen with lower doses. These numbers highlight ongoing efforts to increase the effectiveness of Ozempic for those struggling with obesity.Yet, it's crucial to balance these promising results with real-world insights. The Mayo Clinic and NYU Langone Health recently compared Ozempic's results to traditional weight loss surgery, like gastric bypass and sleeve gastrectomy. Their research revealed that surgery is five times more effective than GLP-1 drugs such as Ozempic, with surgical patients losing an average of 58 pounds after two years versus just 12 pounds for those on the drug for six months. Experts also noted that only 30 percent of patients stick with GLP-1 drugs for longer than a year, and real-world weight loss may be lower than trial results suggest. Surgery, however, isn't without its risks, including potential infections, blood clots, and hernias, and requires strict diet and lifestyle changes afterward.Turning to genetics, Cleveland Clinic research shows that the effectiveness of Ozempic may depend on your DNA. A specific variant in the Neurobeachin gene seems to make some people much more responsive to these medications, leading to 82 percent higher odds of substantial weight loss. This new insight could help doctors tailor treatments so patients get therapies most suited to their genetic profile.Lifestyle stakes are high, and so are concerns about side effects and safety. Recent studies report that Ozempic may cause severe conditions such as gastroparesis, bowel blockages, pancreatic and kidney injuries, and vision problems. Even hair loss is emerging as a potentially significant side effect, especially for women—according to recent findings, female users experienced about twice the rate of hair loss compared to those not using Ozempic.Because of these risks, there are currently over two thousand active lawsuits against Novo Nordisk and other GLP-1 manufacturers, with ongoing multidistrict litigation. These lawsuits allege that the companies did not give enough warning about the dangers, and some patients claim life-changing or life-threatening complications.Compounded GLP-1 drugs, made in pharmacies rather than by pharmaceutical companies, became popular when Ozempic was in short supply. However, the FDA warns that compounded drugs can be risky because they're not evaluated for safety or effectiveness. While the shortage has officially ended, compounded formulations remain in circulation.If you are considering Ozempic—whether as a pill, injection, or a compounded version—talk with your healthcare provider and review your health history, genetic background, and lifestyle goals. Widespread interest has led to changing availability, promising new forms, and more transparent labeling, especially after recent updates about kidney and pancreatic risks.To sum up, Ozempic continues to make waves as both a treatment for diabetes and a potent tool for weight loss. With fresh news about new pill forms, higher effective doses, genetic influences, and ongoing legal cases, it's important to stay informed and make choices based on both science and your personal health needs.Thanks for tuning in to Ozempic Weightloss Unlocked. Don't forget to subscribe to stay up to date on the latest developments. This has been a Quiet Please production, for more check out quiet please dot ai. Some great Deals https://amzn.to/49SJ3QsFor more check out http://www.quietplease.aiThis content was created in partnership and with the help of Artificial Intelligence AI
Beginning this Sunday, Oct. 5 at 5am WGCU will begin airing a weekly interview show called “What's Health Got to Do With It?” that explores the intersection of healthcare and daily life with a focus on guiding listeners on their journeys through the increasingly convoluted medical bureaucracy. We meet its host, Dr. Joe Sirven. He's a practicing neurologist, and professor of neurology and Chairman Emeritus of the Department of Neurology at the Mayo Clinic in Arizona. He's also a well-published author on epilepsy, a former editor-in-chief of epilepsy.com, and he currently serves as the editor-in-chief of Brain & Life en Español.
In 1974, doctors at the Mayo Clinic in Rochester, Minnesota, delivered grim news. They scheduled him for chemotherapy and advised him to bring his family to say their goodbyes. But Rick Hill defied the odds—and the conventional path.Rick Hill's story is more than a tale of survival—it's a legacy of hope, determination, and advocacy for transparency and choice in cancer treatment.For those seeking inspiration in the face of adversity, Rick Hill's life proves that even the darkest diagnoses can lead to a brighter future.
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Across healthcare, new technologies often land in the hands of nurses without their input, adding complexity instead of easing it. In the age of artificial intelligence, more than ever, leaving nurses out of the design process risks creating tools that miss the mark, fail to build trust, threaten safety and security, and can add to the very burdens they're meant to relieve. In this episode of our AI in Play series, we meet Ryannon Frederick, MS, RN, System Chief Nursing Officer at Mayo Clinic, who has restructured nursing leadership teams to ensure nurses identify the problems, co-develop the solutions, and remain partners from design through implementation and testing. Frederick shares how this “for nurses, by nurses” model is transforming innovation at Mayo, making nursing work visible, rebuilding trust in technology, and delivering tools like ambient documentation and nurse virtual assistants that give time back to patients and strengthen the workforce. Find this episode's resources at www.seeyounowpodcast.com, and for more information on the podcast bundles, visit ANA's Innovation Website at: https://www.nursingworld.org/practice-policy/innovation/education/. Have questions for the SEE YOU NOW team? Feedback? Future episode ideas? Contact us at: hello@seeyounowpodcast.com. Resources Enabling nurses' engagement in the design of healthcare technology – Core competencies and requirements: A qualitative study (2024) BMC Nursing. https://www.sciencedirect.com/science/article/pii/S2666142X23000541?via%3Dihub Impact of Bottom-Up Cocreation of Nursing Technological Innovations: Explorative Interview Study Among Hospital Nurses and Managers (2025).JMIR. https://humanfactors.jmir.org/2025/1/e60543/ Global prevalence and contributing factors of nurse burnout: an umbrella review of systematic review and meta-analysis. (2025) BMC Nursing. https://bmcnurs.biomedcentral.com/articles/10.1186/s12912-025-03266-8 Documentation Burden in Nursing and Its Role in Clinician Burnout Syndrome. (2022) ACI. https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0042-1757157 Addressing burnout in the healthcare workforce: current realities and mitigation strategies. (2024) The Lancet. https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(24)00128-5/fulltext
Discover expert insights on kidney stone prevention and management in this podcast episode featuring a physician, dietitian, pharmacist, and patient. Learn about key kidney stone risk factors and explore how dietary adjustments can reduce stone recurrence. Experts discuss fluid intake strategies, medication considerations, surgical indications, and even unconventional questions about roller coasters' impact on stone passage. Tune in for actionable advice, myth-busting discussions, and interprofessional perspectives. On today's episode we heard from: Melanie Betz, MS, RD, CSR, FNKF, FAND is a nationally recognized renal dietitian and the Founder & CEO of The Kidney Dietitian. She is a Certified Specialist in Renal Nutrition and a Fellow of both the National Kidney Foundation and the Academy of Nutrition & Dietetics. Melanie has published extensively on kidney stone prevention and nutrition, and has presented at numerous state, national, and international conferences on the topic. Through her clinical work, research, and educational outreach, she is dedicated to helping patients and professionals understand the critical role of diet in kidney health. Mark Garofoli, PharmD, MBA, BCGP, CPE, CTTS is a Clinical Associate Professor at West Virginia University School of Pharmacy and a Clinical Pain & Addiction Pharmacist. With expertise in pain management, substance use disorders, and geriatric care, he brings both clinical and personal perspectives to kidney stone discussions. Mark has shared his experience through the Pain Pod podcast, PAINWeek presentations, and a published article detailing his own kidney stone journey. Mary Raines, CRA is a retired clinical research associate with more than 30 years of experience in medical research. After learning she needed a kidney transplant, she dedicated herself to advocacy and now serves as a Patient Advocate with the National Kidney Foundation and other kidney health organizations. Mary brings both professional expertise and personal experience to her work, amplifying the voices and needs of people living with kidney disease. Andrew Rule, MD, MSc is a Professor of Medicine and Consultant Nephrologist at the Mayo Clinic in Rochester, Minnesota. He divides his time between clinical care, research, and education, with a particular focus on kidney stone disease and its link to chronic kidney disease. Dr. Rule has published extensively on the epidemiology of kidney stones and provides specialized care in the Mayo Clinic's nephrology stone clinic. Bryan Tucker, DO, MS, FASN is an Assistant Professor of Medicine in Nephrology at Baylor College of Medicine, where he serves as a clinician educator teaching medical students, residents, and fellows while caring for patients in both inpatient and outpatient settings. He holds a master's degree in nutrition from Columbia University and completed his nephrology fellowship at Yale. A Fellow of the American Society of Nephrology, Dr. Tucker has authored numerous peer-reviewed publications and book chapters and is an active contributor to The Kidney Commute podcast. Additional Resources: Kidney Stone Information Earn CME Credit Here Do you have comments, questions, or suggestions? Email us at NKFpodcast@kidney.org. Also, make sure to rate and review us wherever you listen to podcasts.
Earlier this week, President Trump and his Administration made claims about the correlation between autism and Tylenol or acetaminophen use during pregnancy, warning pregnant women not to use the drug. A mounting backlash has followed with medical and autism experts alike disagreeing with Trump's claims. The American College of Obstetricians and Gynecologists and the American Academy of Pediatrics continue to recommend acetaminophen in pregnancy and childhood when used at the lowest dose for the shortest duration. Mayo Clinic trained Rheumatologist Dr. Alfred Miller takes aim with the claims and believes the Trump Admin. is ignoring scientific studies regarding autism. Dr. Miller joined us to discuss.
En Guerrero Marina y FGR incineran 900 kilos de cocaína Oaxaca ordena a burócratas usar ropa indígena cada miércoles Daniel Hidalgo será nuevo presidente de la Academia de Cine Más información en nuestro podcast
A-Block (2:30) SPECIAL COMMENT: After perhaps the most hapless 96 hours of his presidency, the worst 96 hours of the worst presidency of ALL TIME, the most FAIL in the shortest span… the mentally-deteriorating, untethered-from-reality Trump… must RESIGN. And take his idiot sycophants with him. The last 96 hours: His U.N. speech, sounding like an escapee from a psych ward. His Tylenol news conference, sounding like an escapee from a psych ward who’s been living on the street for a month. His suggestion NATO countries shoot down Russian jets. His sudden embrace of Zelensky, either another stall or a stupid dare to Putin. MAGA’s RAGE AT his sudden embrace of Zelensky. The cover of a London right wing daily: his picture and in 72-point type, the word “DERANGED.” The ICE shooting in Dallas; his sadistic Homeland chief pretending the victims were agents when they were detainees; his idiot simpering Vice President pretending the victims were agents when they were detainees; his corrupt venal FBI director pretending the victims were agents when they were detainees. His ICE chief not denying he took $50,000 in a paper bag. His staff THEN denying he took $50,000 in a paper bag. His cancellation of a meeting with Democrats making sure if there’s a government shutdown it’s all his fault. His crackpot pal Milei crashing the Venezuelan economy and needing us to bail him out. His paranoia over the stopped teleprompter at the U-N that was his White House staff’s fault. His paranoia over the stopped escalator at the U-N that was his own vanity videographer’s fault. His desire to arrest the U.N. escalator technician or the U-N escalator button pusher. His desire to arrest the escalator AND James Comey. The election of Raul Grijalva’s daughter to Congress. The fact that Adelita Grijalva will be the last Representative needed to force a vote on releasing the Trump Epstein Files. His self-humiliation at the Kirk Memorial. ABC reinstating Jimmy Kimmel. Meaning Disney told him to eff off. Meaning the National Football League told him to eff off. Meaning they all told his propagandists at Sinclair to eff off. Kimmel then shoving him in a locker using only a monologue. Kimmel getting a record 6 million viewers and 22 more online in the first TWENTY hours. Kimmel and his show getting new life and maybe a new contract. His self-owning confession that HE and his goons used threats to get Kimmel cancelled. The fact that Kimmel, and ABC, and Bob Iger, and Disney, and America told Trump to SHOVE HIS THREATS. And that’s just since Sunday night. You lost to an escalator. Resign. Take Vance with you. Take Noem with you. Take Ho-man with you. Take Milei with you. LEAVE the Epstein Files. B-Block (32:53) THE WORST PERSONS IN THE WORLD: Jason Whitlock says eff everybody, this is Christ-land and he won't be brainwashed any more (no brain, no pain). Derrick Van Orden says Kirk was Jesus and you don't F with the Jesus so defund The Mayo Clinic (he should go there and get CT scanned) and Kristi Noem says a tweet saying she'd have a bad day was terrifying for her. This is a piece of crap who in her spare time murders puppies. C-Block (42:00) THINGS I PROMISED NOT TO TELL: The New York Post BS firehose points at a couple of liberals at a time, then it rotates away, but eventually it makes a full circle and comes back to you. For me this has been going on since the mid-1990's and it's just started again. If you'll permit, here's a brief history.See omnystudio.com/listener for privacy information.
In this episode, Bill and Michael unpack the “Last 8%” of conversations — the toughest parts we often avoid but that carry the most impact. They explore how leaders can build cultures of high connection and high courage, share personal stories from healthcare and startup leadership, and offer strategies for handling tough truths, hiring challenges, and team performance. Bill Benjamin, a global keynote speaker who blends practicality with science in his approach to leadership. With degrees in Mathematics and Computer Science, Bill uses brain-science to help people master emotional intelligence, perform under pressure, and build what he calls a high-performance “Last 8%” culture. Audiences appreciate his high energy and engaging style, whether he is speaking to surgeons, the U.S. Marines, NASA engineers, or executives at Amazon, Intel, and Goldman Sachs. Bill does not just share theory. He is open about the struggles he faced early in his career and how applying the strategies he now teaches made him a stronger leader, husband, and father. He is funny, relatable, and committed to understanding the real challenges organizations face, weaving those directly into his sessions. That is why top organizations from the Mayo Clinic to NASA trust him when performance and leadership matter most. HBR Article: https://hbr.org/2025/09/the-secret-to-building-a-high-performing-team Website: https://ihhp.com/
In this episode of the Optimal Aging Podcast, Jay Croft speaks with Dr. Jonathan Graff-Radford, a Mayo Clinic neurologist and co-author of the new edition of the Mayo Clinic Guide to Alzheimer's and Other Dementias. They discuss how Alzheimer's disease begins 20 years before symptoms appear, what can be done to prevent or delay it, and what health and fitness professionals working with people over 50 need to know now.Dr. Radford shares powerful new insights on early detection tools, lifestyle factors like exercise and hearing loss, and how fitness protocols can support cognitive health. You'll also hear how dual-tasking workouts, VO2 max, and neuroplasticity play a role in long-term brain health.If you serve older adults in health, fitness, or wellness, this is a must-listen.
We start with the on-going invasion of many Wisconsin communities by energy and water sucking data centers. While profiting Silicon Valley, Wall Street, and Big Utilities these projects threaten to accelerate runaway climate change and spike already unaffordable utility prices. While state and local economic development boosters, including the Evers Administration, throw public money at data centers without considering the massive environmental costs and limited economic impact, a few brave communities are standing up in places such as Menomonie and Caledonia. We need to refocus public policy on addressing the climate crisis, not economical development boondogles that light the planet on fire. We encourage people to attend this Sunday's Climate March at the Capitol in Madison at Noon. Meanwhile Trump, Vance, and their minions rush to politicize the violent attack on ICE office in Dallas before the facts are in, blaming Democratic and left wing truth-telling about the abuses of Trump's immigration crackdown. There is a problem with political incendiary language, that it come from the President, Vice President, and MAGA, not elected progressives and mainline Democrats. We talk about the potential of a government shutdown, and the Trump Regime impact in Wisconsin this week, including Derrick Van Ordin's demand to cut off federal dollars to the City of Eau Claire, Ellsworth, and Mayo Clinic in retaliation for social media posts. Citizen Action Board member and former state Representative Sandy Pasch joins us to warn our listeners about a terrible new bill in Madison that restricts free speech in the name of fighting antisemitism by making legitimate and First Amendement protected cricism of Israel into hate speech. The bill is yet another authoritarian attempt to empower governmet crackdowns against civil society groups and free speech. Sandy calls for our listeners to reach out to their state representative and senators to oppose AB 446, and support alternative legislation that meaningfully addresses antisemitism. Finally, we welcome Chris Gooding, Theology professor and union leader at Marquette University, to update our listeners on the Jesuit university's union busting in the name of God. We discussed how this anti-union strategy spread this month to Loyola Marymount University in Los Angeles, where the university walked away from negotiations with their workers, prompting outrage on campus and a strike vote.
The Canadian Bitcoiners Podcast - Bitcoin News With a Canadian Spin
FRIENDS AND ENEMIESThis week we welcome two esteemed medical professionals to discuss the state of Canadian healthcare, surgery wait times, the rise in demand for private care options in Canada, and more.A little about our guests:Dr. Brian Day is a prominent Canadian orthopedic surgeon, health researcher, and advocate for reforming the Canadian healthcare system, known for his controversial stance favoring private healthcare options and his legal challenge to B.C.'s Medicare Protection Act, which he ultimately lost. He is the founder of the Cambie Surgery Centre in Vancouver and a former president of the Canadian Medical Association. His advocacy is detailed in his book, "My Fight for Canadian Healthcare," and he remains a significant figure in discussions about healthcare policy in Canada.Dr. Mohammad Zarrabian is the current Head of Spine Surgery at Hamilton Health Sciences. He is a double fellowship-trained spine surgeon, having completed neurosurgical and orthopedic spine surgery fellowships at the Mayo Clinic and Toronto Western Hospital, University of Toronto. Buy Dr. Day's Book Here: https://a.co/d/4bKrBhE____Join us for some QUALITY Bitcoin and economics talk, with a Canadian focus, every Monday at 7 PM EST. From a couple of Canucks who like to talk about how Bitcoin will impact Canada. As always, none of the info is financial advice. Website: www.CanadianBitcoiners.comDiscord: https://discord.com/invite/YgPJVbGCZX A part of the CBP Media Network: www.twitter.com/CBPMediaNetworkThis show is sponsored by: easyDNS - https://easydns.com EasyDNS is the best spot for Anycast DNS, domain name registrations, web and email services. They are fast, reliable and privacy focused. With DomainSure and EasyMail, you'll sleep soundly knowing your domain, email and information are private and protected. You can even pay for your services with Bitcoin! Apply coupon code 'CBPMEDIA' for 50% off initial purchase Bull Bitcoin - https://mission.bullbitcoin.com/cbp The CBP recommends Bull Bitcoin for all your BTC needs. There's never been a quicker, simpler, way to acquire Bitcoin. Use the link above for 25% off fees FOR LIFE, and start stacking today.256Heat - https://256heat.com/ GET PAID TO HEAT YOUR HOUSE with 256 Heat. Whether you're heating your home, garage, office or rental, use a 256Heat unit and get paid MORE BITCOIN than it costs to run the unit. Book a call with a hashrate heating consultant today.The Canadian Bitcoin Conference - https://canadianbitcoinconf.com/The PREMIER Bitcoin Conference, held annually in the great white North, where Bitcoiners come together to share stories, build momentum and have a great time while doing so. Whether your a pleb, business, newcomer or OG, the Canadian Bitcoin Conference wants to see you in Montreal, October 16-18 2025. Don't miss this one!
Send us a textThe world of invisible illness is a lonely place where "you look fine" becomes a painful refrain from well-meaning friends and family who can't see the war raging inside your body. For six years, I've navigated life with rheumatoid arthritis—an autoimmune disease where my body attacks my joints, causing inflammation, pain, and progressive damage from my fingers to my hips.This deeply personal episode peels back the curtain on what it's truly like living with chronic pain that others can't see. I share my diagnosis story, the countless medications and supplements that fill my daily routine, and how I've had to completely reimagine my identity. From the steroid shots that provide temporary relief to the heated blankets that have become my constant companions, I walk you through the practical realities of managing an autoimmune disease.But beyond the physical challenges lies a profound psychological journey. I've discovered what I call the "migraine hack"—how people readily show empathy for conditions they understand while dismissing autoimmune flares with a casual "can't you just suck it up?" I share the valuable Column A, B, C exercise from the Mayo Clinic that's helping me accept my new reality: Column A represents who I was before, Column C reflects my worst days, and Column B is the new identity I'm creating between those extremes.Whether you're battling an invisible illness yourself or love someone who is, this conversation offers both practical insights and emotional validation. For those suffering, you're not alone in this struggle. For those supporting someone with chronic illness, understanding is the greatest gift you can offer. Because when someone says they're in pain, believing them costs nothing—but dismissing their experience costs them everything. Thanks again for listening. Don't forget to subscribe, share, and leave a FIVE-STAR review.Head to Dwanderful right now to claim your free real estate investing kit. And follow:http://www.Dwanderful.comhttp://www.facebook.com/Dwanderfulhttp://www.Instagram.com/Dwanderful http://www.youtube.com/DwanderfulRealEstateInvestingChannelMake it a Dwanderful Day!
In this episode of the Investing in Integrity podcast, Ross Overline, CEO and co-founder of Scholars of Finance, welcomes Bill George, Legendary Business leader and former CEO of Medtronic, Harvard Business School professor, and board member at Goldman Sachs, for a candid conversation on authentic leadership in finance. Drawing on decades of executive and boardroom experience, Bill highlights why integrity, emotional intelligence, and purpose-driven decision-making are vital in today's financial landscape. Together, they discuss strategies for combating greed, building sustainable long-term value, and staying true to one's moral compass even in high-stakes environments. The discussion also explores navigating ethical challenges in the age of AI and ensuring finance remains a force for good. Whether you're an aspiring finance professional or a seasoned investor, this episode offers valuable insights on leading with character and transforming business through values-based leadership.Meet Bill George:Bill George is an Executive Education Fellow at Harvard Business School and former chairman and CEO of Medtronic, where he led from 1991 to 2001. Earlier in his career, he held senior roles at Honeywell, Litton Industries, and the U.S. Department of Defense. A prolific author, Bill has written several influential books on authentic leadership, including True North. He has served on the boards of Goldman Sachs, ExxonMobil, Novartis, Target, and the Mayo Clinic. Recognised with honors such as the Bower Award for Business Leadership, Bill is widely respected for advancing values-driven leadership in business and society.
Host: Darryl S. Chutka, M.D. Guest: Matthew (Mark) Melin, M.D. Vascular wounds can be quite challenging. If untreated, they can lead to infection, even sepsis, hospitalization and occasionally, amputation. Effective treatment requires an accurate diagnosis and recognition of the specific type of vascular wound you're dealing with. Even when the type of wound is correctly identified and is being treated appropriately, healing can be slow. What diagnostic tools are available to help us? How does a venous insufficiency ulcer differ from an arterial ulcer? What's the best treatment for these wounds and when should we refer our patient to a vascular specialist? The topic for this podcast is “Vascular Wound Treatments” and these are some of the questions I'll be asking my guest, Matthew (Mark) Melin, M.D., a vascular specialist from the Department of Cardiovascular Medicine at the Mayo Clinic. Mayo Clinic Talks: Vascular "What's Circulating" | Mayo Clinic School of Continuous Professional Development Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts
Ischemia with No Obstructive Arteries (INOCA) in 2024 Guest: Claire Raphael, M.B.B.S., Ph.D. Host: Sharonne Hayes, M.D. INOCA is a common condition. It is an acronym that stands for ischemia with non-obstructive coronary artery disease. We discuss when to consider a diagnosis of INOCA, how to diagnose it and how to treat patients. Topics Discussed: What is INOCA? Who is at risk for INOCA? How do we manage INOCA? Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode. Podcast episode transcript found here.
Welcome to the Oncology Brothers podcast! In this episode, we dive deep into the world of neuroendocrine tumors (NETs) with renowned expert Dr. Thor Halfdanarson from the Mayo Clinic. Join us as we explore: • The critical factors in diagnosing NETs, including origin, grade, histological features, and Ki-67. • The importance of differentiating between functional and non-functional tumors and how this impacts treatment decisions. • Dr. Halfdanarson's treatment paradigm, including the use of somatostatin analogs, radioligand therapy, and other targeted treatments. • Monitoring strategies for patients, including the role of imaging and tumor markers like 5-HIAA and chromogranin. • Insights into the evolving role of immunotherapy and next-generation sequencing in managing high-grade neuroendocrine carcinomas. Whether you're a healthcare professional or simply interested in the latest advancements in oncology, this episode is packed with valuable information and practical insights. Follow us on social media: • X/Twitter: https://twitter.com/oncbrothers • Instagram: https://www.instagram.com/oncbrothers • Website: https://oncbrothers.com/ Don't forget to subscribe for more discussions on cutting-edge cancer treatments and expert opinions in the field of oncology!
Should MRI-guided interventions be on your radar? Find out why the future of interventional radiology might lie in MRI guidance with experts Dr. Clifford Weiss from Johns Hopkins University and Dr. David Woodrum from the Mayo Clinic.---This podcast is supported by:Medtronic Emprinthttps://www.medtronic.com/emprint---SYNPOSISThe physicians join host Dr. Chris Beck to explore the benefits of MRI guided procedures, including superior imaging capabilities and reduced radiation exposure. Dr. Weiss and Dr. Woodrum detail the challenges and barriers to adoption, like the intricate set up needed to protect equipment from a strong magnetic field. They highlight the significant technological advancements and collaborations between MRI and device companies that are set to make MRI guided interventions more accessible and practical for everyday use. They also discuss the reimbursement paradigm for MRI guided biopsies and how similar the algorithm is to CT guided procedures.The episode closes with unique insights for young physicians on training opportunities and the promising future of MRI guided interventions for trainees looking to bring a different approach to their future practices.---TIMESTAMPS00:00 - Introduction05:13 - The Advantages of MRI in Interventional Radiology13:44 - Technical Insights and Challenges of MRI Guided Procedures18:46 - Future Prospects and Industry Developments in MRI Guided Interventions31:01- Development of Hybrid MRI Rooms48:19 - Economic Considerations and Reimbursement52:33 - Community Support for MRI Interventions56:41 - Conclusion and Final Thoughts---RESOURCESInternational Society for Magnetic Resonance in Imaging:https://www.ismrm.org/
Host: Darryl S. Chutka, M.D. Guest: Neha P. Raukar, M.D., M.S. Women in medicine have made significant strides over the past few decades, yet some still face a variety of challenges and barriers. They commonly encounter inequalities that can affect their professional growth and overall well-being. Common issues include pay disparity, underrepresentation in leadership positions and gender discrimination, just to name a few. Some medical specialties tend to be male-dominated and can be less welcoming to women. As a result, women physicians have higher rates of professional burnout and often experience a less satisfying career. My guest for this podcast is Neha P. Raukar, M.D., M.S., an emergency medicine physician at the Mayo Clinic. The topic we'll be discussing is “Claiming Your Voice and Why Women in Medicine Need a Clear Professional Narrative”. Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts
What does a longevity doctor actually do and how is this different from what you'd get from a traditional doctor, holistic practitioner, or even functional medicine expert? In this episode, I sit down with Dr. Darshan Shah, a longevity doctor based in Los Angeles, to uncover what “next-level health” looks like when science meets cutting-edge treatments you won't find anywhere else. We dive straight into some of the most advanced therapies and what they really mean for midlife women: Therapeutic Plasma Exchange and why this is becoming a hot topic in the world of anti-aging and disease prevention NAD treatments: are they truly beneficial, or is it time to reconsider how we approach NAD? Breast health and screening: what every woman should know and why early detection strategies are evolving Darshan Shah, MD, is a health and wellness specialist, board-certified surgeon, published author, entrepreneur, and founder of Next Health, the first, largest and fastest-growing health optimization and longevity clinic. He began his career at an accelerated MD program and earned his medical degree at the age of 21, becoming one of the youngest doctors in the United States. He continued his training at the Mayo Clinic, and earned his MBA from Harvard Business School in 2015.As a longevity medicine specialist, he has advised thousands of patients on how to optimize their well-being and extend their healthspan and lifespan. Extend with Dr. Darshan Shah Podcast: https://podcasts.apple.com/us/podcast/welcome-to-extend-with-darshan-shah-md/id1773578243?i=1000673875409 Episode with Dr. Sara Szal (Gottfried) https://podcasts.apple.com/us/podcast/89-sara-szal-md-why-80-of-women-experience-brain-fog/id1773578243?i=1000723568927 https://www.drshah.com/biomarkers Contact Dr. Darshan Shah Website: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd Email: contact@drshah.com Give thanks to our sponsors: Try Vitali skincare. 20% off with code ZORA here https://vitaliskincare.com Get Primeadine spermidine by Oxford Healthspan. 15% discount with code ZORA here. Get Mitopure Urolithin A by Timeline. 20% discount with code ZORA at https://timeline.com/zora Try Suji to improve muscle 10% off with code ZORA at TrySuji.com Try OneSkin skincare with code ZORA for 15% off Join Biohacking Menopause before October 1, 2025 to win a Flexbeam red light therapy device. Or save 10% with code ZORA at https://recharge.health Join the Hack My Age community on: YouTube: https://youtube.com/@hackmyage Facebook Page: @Hack My Age Facebook Group: @Biohacking Menopause Private Women's Only Support Group: https://hackmyage.com/biohacking-menopause-membership/ Instagram: @HackMyAge Website: HackMyAge.com
Dr. Adam Power, co-founder and Chief Medical Officer at Front Line Medical Technologies, shares his fascinating journey from a background in vascular surgery to developing COBRA-OS, a groundbreaking device for hemorrhage control. He discusses the challenges and milestones in bringing this life-saving technology to market, the impact of the device in trauma and emergency care, and innovative future applications, including its unexpected use in non-traumatic cardiac arrest. Guest links: https://frontlinemedtech.com/ Charity supported: Canadian Cancer Society Interested in being a guest on the show or have feedback to share? Email us at theleadingdifference@velentium.com. PRODUCTION CREDITS Host & Editor: Lindsey Dinneen Producer: Velentium Medical EPISODE TRANSCRIPT Episode 064 - Dr. Adam Power [00:00:00] Lindsey Dinneen: Hi, I'm Lindsey and I'm talking with MedTech industry leaders on how they change lives for a better world. [00:00:09] Diane Bouis: The inventions and technologies are fascinating and so are the people who work with them. [00:00:15] Frank Jaskulke: There was a period of time where I realized, fundamentally, my job was to go hang out with really smart people that are saving lives and then do work that would help them save more lives. [00:00:28] Diane Bouis: I got into the business to save lives and it is incredibly motivating to work with people who are in that same business, saving or improving lives. [00:00:38] Duane Mancini: What better industry than where I get to wake up every day and just save people's lives. [00:00:42] Lindsey Dinneen: These are extraordinary people doing extraordinary work, and this is The Leading Difference. Hello, and welcome back to another episode of The Leading Difference podcast. I'm your host, Lindsey, and today I'm excited to introduce you to my guest, Dr. Adam Power. Dr. Power is a leader in innovative medical devices for trauma and emergency care that is committed to lowering the barriers and bleeding control and resuscitation. Dr. Power was instrumental in the development of COBRA-OS, drawing on his unique clinical viewpoint and expertise to ensure utmost patient safety and assist with the company's global expansion. In addition to his current role as co-founder and Chief Medical Officer at Front Line Medical Technologies Incorporated, Dr. Adam Power is a vascular surgeon in the division of vascular surgery at Western University, which he joined in the fall of 2012, and he is involved in all aspects of academics and clinical care. Also, Front Line was just named the 2025 Medical Device Technology Company of the Year, so I definitely wanted to highlight that too. All right. Well, thank you so much for being here today, Adam. I'm so delighted to speak with you. [00:01:55] Dr. Adam Power: Yes, it's a pleasure to be here. Thank you. [00:01:57] Lindsey Dinneen: Of course. Well, I'd love if you would start by sharing a little bit about yourself, your background, and what led you to what you're doing today. [00:02:05] Dr. Adam Power: Sure, I'd love to. So I'm a Canadian. I grew up on the east coast of Canada and was always interested in science and math and those types of things. I think, importantly, I grew up with an identical twin brother as well. So we really didn't know what we wanted to do with our lives, and ultimately we're good in science and math and ended up in medicine. And then both of us, when we got into medicine, we weren't sure exactly what we wanted to do in medicine, and ultimately both of us became surgeons. He became a urology surgeon, and I became a vascular surgeon, where we joke that we're both plumbers. I deal with the red stuff and he's the yellow stuff. But I did my initial medical school out on the east coast of Canada and then I did my general surgery training, which also involved trauma training, and then did a Master's of Bioscience Enterprise, which was basically biotech business from the University of Cambridge in the UK. When I finished my general surgery training, I continued on and did vascular surgery training at Mayo Clinic down in the US, and since that time after graduating from there, I've been at Western University in London, Ontario, Canada, for the past 13 years practicing as a vascular surgeon and an academic vascular surgeon. But when I was here at Western, I was always interested in innovation. I filed my first patent as a resident way back when, and have filed many over the years. But ultimately, if I was ever gonna see anything that came outta my head and was actually used in a patient or I could actually use in a patient, I figured I'd have to do it. I knew that I couldn't do it by myself. And so, I was very fortunate to meet my co-founder Dr. Asha Parekh. She's a PhD, biomedical engineer, extremely smart jack of all trades, and we teamed up now about eight years ago. We met here at Western, teamed up and really took an idea right out of our heads and patented it and raised money for it, prototyped it, brought it all through the regulatory steps to approvals, built a quality system and ultimately got it out onto the market in Canada, US, Europe, now Australia, and more to come. So the commercialization piece is what we've been focusing on over the past three years. And it's been really fun, but very exhausting but very rewarding as well. I think I'll stop there because I've been blathering on, but... [00:04:39] Lindsey Dinneen: No, it's fantastic. I really appreciate it. Plus, it's really fun to hear about your trajectory and so, okay, so you've teased us a little bit about this company of yours and this innovation of yours. Can you now share a little bit more about that and the development of it over time? [00:04:55] Dr. Adam Power: Yes, of course. Well, I mean, thing that we recognized early on is, and I'll just explain how I normally explain it, is if you have bleeding, it's a hemorrhage control device. And so if you have bleeding in your extremities, then you can often either put pressure on it or you can put a tourniquet on it. The problem when you have internal bleeding in the torso is that you can't actually put direct pressure on it, and there's no tourniquet that necessarily works for intraabdominal, intrathoracic bleeding. And when people bleed to death before coming to hospital, I mean, they're bleeding in these areas. You can empty almost your entire blood volume into your chest or into your abdomen. And this does account for a significant number of fatalities in all environments, basically in the trauma environment. That's military, that's pre-hospital, that's any time that that people are bleeding from internal organs. And so, because this is such a problem, the old fashioned way to fix it is to open up someone's chest and put a clamp on the aorta. So what does that do? Is it basically above the clamp, keeps blood flowing. The remaining blood in the body keeps blood flowing to the brain and the heart, keep you alive. And then below the clamp, it stops sort of the hemorrhaging from the spleen or the liver or whatever. So there's two things going on. One above the clamp and two below the clamp. But opening up somebody's chest in, you know, side of the road or in the emergency department really is impossible. You need highly skilled people like vascular surgeons like myself to be able to do this. And even if we were at the side of the road, we don't have the resources available to keep a patient alive. So there is this idea that we could do this minimally invasively, sort of accomplish this through minimally invasive means. And this, the idea of doing REBOA, which is an acronym-- Resuscitative Endovascular Balloon Occlusion of the Aorta-- came into being. This was probably 15, 20 years ago now. It wasn't necessarily a new idea. It had been done since the Korean War. There was somebody actually put a balloon up into someone's aorta to stop bleeding, but it came back again and was starting to be used a little bit more because. And so really the idea is to, through the femoral artery in your groin where you can feel a pulse, you introduce initially a sheath, which is your access point, and then you place the device up through the sheath, up into the aorta and inflate a balloon in the aorta. So instead of an external clamp, it's an internal balloon clamp that keeps blood flowing above the balloon and stops the blood flowing from below the balloon. Initially these devices were as big as my baby finger, like they were massive. And so if you put them in and you took it out, there was a big hole in the artery, had to cut down on the artery and repair the artery. But as it got more and more advanced and technology advanced, they become smaller and smaller. So that's really where we came in. The initial devices were 12 French, about the size of my baby finger. And then it advanced to Seven French and all of a sudden Seven French-- and these are diameter, French sizes are basically diameter-- and so when it went from 12 to seven French, now we could start doing it through the skin without actually cutting down on the artery. But that Seven French size was still very large and you're putting this in the hands of people that don't do this all the time. And so, we had the idea to bring it down even further now to Four French. And so this is essentially the size of an IV. And so you put a tiny little IV in somebody's femoral artery. And lots of different people can do that. And then you advance the device up in, inflate the balloon and you can magically occlude the aorta. In our first study that we did, the first inhuman study, we averaged about just over a minute to occlude someone's aorta, which was really fast to be able to get that amount of control that quickly. So that, that was really been the advancement is to decrease the access size, make this whole procedure simpler so that so that we can essentially save more lives. [00:09:08] Lindsey Dinneen: Okay, so thank you so much for sharing a little bit about that. Can you tell me about the beginnings of this innovation and how you brought it to market? Because it's really wonderful to hear all the success, and I'm so excited to hear that it's spreading, you have presence all over the place now. But you know, that's not an easy pathway. And I'm curious if you could walk us through a little bit about that decision to go, "You know what? We have a solution to a known problem, we can make this happen." And then how did you actually go about doing that? [00:09:42] Dr. Adam Power: Yeah. I think, I mean, I make it sound fairly straightforward, like a nice story, but it certainly was not that. I mean, we were very lucky I would say, that we had a lot of great advisors and mentors that we figured that we try not to fail early, fail fast. We wanted to make this one as successful as possible. So before we made any decision, we often would consult our mentors. And I'm a surgeon. I like to shoot first, ask questions later. My partner is not. And so I think we, we strike an excellent balance between not just the engineering and clinical side of things, but also from driving a business forward, getting all the information, but helping to get decisions made and moving forward. You know, starting out, we really had to choose the right sort of fit for what we wanted to pursue. We like to say it checked all the boxes. It checked all the boxes as far as even where we are. We're in Canada, we're not in a tech triangle where there's tons of funding opportunities. We knew we would be limited from a funding perspective, so we couldn't choose something that necessarily required a hundred million dollars to start up. So, you know, we had this device that we knew that we could fundraise for it. And then once it was fundraised, it was simple enough that we could get it manufactured. We chose to go the OEM route for the original equipment manufacturer, so we didn't have to build a manufacturing facilities ourselves. And then really from there, and building a quality system in the regulatory, we did work with a lot of consultants, that was both positive and negative experience. We had great consultants. We had not so great consultants. But really what our our goal was, is to learn the process ourselves. And so there's always manuals for things, even from the FDA perspective. They give out great documentation about what is supposed to go into an FDA application. And we dug into that. We really tried to understand. We did not trust anyone. That's one of my rules in surgery is, "don't trust anyone, not even myself." So we really didn't trust our consultants, and we tried to double check and triple check everything so that we didn't make mistakes. And of course, we did make mistakes and had to go back to the drawing board a few times. But as much as we wanted to get this out there, we really did wanna learn the process and know the process because ultimately we're the ones that are responsible to the patients in the end, and we needed to make sure that we had a handle on each and every step of the way. We, of course, because of that, were maybe not as quick as we could have been but in other places we became more efficient because, as we learned the process, getting feedback back and doing it right the first time, it really made a difference. So. [00:12:39] Lindsey Dinneen: Yeah, absolutely. Of course. Yeah, and I appreciate you going into a little bit more of the nitty gritty details 'cause it is so fun to hear the success stories, but of course, as you go along, there's that pathway to success. And it's helpful to understand that yeah, it's gonna be potentially a long road, sometimes windy, sometimes weird, but at the same time that it is possible. So as you look to the future with your company, what are you thinking of in terms of the future? Are you going to continue down this pathway and continue with iterations of this device? Are you thinking of new devices to introduce as well? Or, what are your thoughts for the future? [00:13:18] Dr. Adam Power: Yeah. And I have to be very careful what I say here, obviously. I can share generically what our thoughts are. We love this. Ultimately there was no better feeling than to use-- I mean, I've used my device to save a patient. And, you know, I would say that Asha, who's my co-founder, she cares. I'm a physician, but she cares about the patients just as much as I do, as does everyone in our company, which is really quite rewarding. But the future, what does the future hold? We really want this to get to everywhere. Yes, we're in lots of different countries ,have commercialized really all around the globe, but we really wanna go deeper into a lot of these geographies and really help as many people as possible. We realize that we can't do it on our own and are gonna need help. And so that's, we're in a growth phase right now of our company and we're looking for strategic collaboration. We're looking for those opportunities to deepen our ties and in all the different geographies. That being said, we are inventors and of course we have an idea every day about what we could improve on. But as far as the pipeline goes for our company, we are focusing on some very specific up and coming applications that we hope to have in the next couple of years. And I also wanna say that, I talked about trauma and bleeding, but the more exciting side of aortic occlusion has really been the applications. And you'd think, okay, it makes sense for trauma to be able to stop blood flow and stop bleeding. But some of our recent successes have been through postpartum hemorrhage. And there is this really, terrible condition called placenta accreta, where the placenta grows into the uterus and when you deliver the baby either by C-section or by delivery, and then the placenta attempts to be delivered, it tears, and you can have torrential bleeding. And, and so our device is being used in these women who are pregnant when inflicted with this condition and helping to decrease blood transfusions, helping to save a mother's life. So that's been really amazing. And then next on the horizon is strangely there's, it's not even a bleeding application. We've done some research and there's research going on globally about using aortic, minimally invasive aortic occlusion for non-traumatic cardiac arrest. And so if, which is really, again, it's like, "Oh my gosh, does this thing do everything? It might make your supper tonight if you're not careful." So it, so what happens there is that if somebody drops dead basically in front of you, and you start CPR, if you start pushing on their chest and pushing on their heart, you're pushing blood to the whole body. And the way you get someone back to life is if you can get the heart muscle oxygenated again. So if you put an aortic occlusion balloon up close to the heart, every time you push, you're directing blood right into the coronary arteries and right into the brain as well. And so what we're seeing is that there's increased return of spontaneous circulation rates when you do this with CPR. And there are different trials around the world that if this shows that there's an increase in survival or in better neurological survival, this will be the first time that we've really changed the script on cardiac arrest since advanced cardiac life support came out many years ago. So this, again, is very exciting for a simple device to be able to make that much impact in all these different areas. So, you know, we have a lot to focus on right now, even growing into the future because some of these, like cardiac arrest, are quite early on. So we don't wanna lose sight of this great original product, but we do think all the time about different pipeline ideas that could help other patients. [00:17:18] Lindsey Dinneen: Yeah, but, and to your point, even the amazing other use cases for this incredible device, like you said-- maybe it's gonna make us dinner next-- but the idea being that, who knows? I mean, there's so much more to discover even now, which makes me excited just to think about how many more use cases you could have for it and how many more people you could save. So, speaking of that, are there any stories that kind of stand out to you, moments that you've had where, you know, either through your day job, so to speak, being a vascular surgeon, but also being the co-founder of this company that really sort of affirmed to you that, "You know what? I am in the right place at the right time, in the right industry." Just those moments that really stick with you. [00:18:05] Dr. Adam Power: Yeah, I mean, it obviously all stems back to the patient and what patients are impacted. And I remember, the first time that the device was used at our hospital, one of the radiologists called me in and said, " We need to use one of these balloon occlusion devices for a patient that's been in an accident." And so I went in and I said, "I actually have the device that my partner and I created. We can use this for the patient." And so we started using it for the lady that was involved in a very serious accident, had a pelvic fracture, and she was a Jane Doe at that particular time. She was anonymous. And anyway, we noticed that she had actually had some vascular surgery done based on her angiograms, and I leaned over and I-- so she was sedated, but she was awake-- I said, "Have you had vascular surgery? Who's your vascular surgeon?" And she said, "It's Dr. Power. He's such a nice man." And so I was actually helping one of my patients. That was pretty crazy. [00:19:04] Lindsey Dinneen: Oh. [00:19:05] Dr. Adam Power: Also from my hospital, when I heard one of my junior residents was able to save someone's life. So, you know, junior residents are often good, but they're not trained surgeons. And so to have a simplistic device that one of my residents could actually place and help someone, that's pretty amazing too. There's also been times where like even the postpartum hemorrhage, we hear the first cases in the States of saving mother and baby. That's pretty incredible. Or that we donated some devices to the Ukraine conflict as well, and we heard that it saved some soldiers' lives as well. And there's different military groups that, that use our device and save soldiers. So it's all back to the patient. And hearing those success stories and hearing about somebody alive because of this particular device, because of all this effort that we've put in. I mean, it's really makes it worthwhile. It sounds kind of corny, but as a surgeon, I can help one person at a time, but as somebody involved in industry and medical device industry, I don't even have to be there. You know, this device can help long after I'm gone. The tricky part of it, being the Chief Medical Officer is, I usually only have to worry about my patients. Now I have to worry about everybody worldwide and the device being used. That was a little hard to wrap my head around initially, but yeah. [00:20:28] Lindsey Dinneen: Yeah, of course. But the ripple, the ripples, the impact that you get to have because of this device and because of your diligence getting it to market, because it isn't an easy path, and that's incredible. So thank you for doing the work that you're doing. That's not easy and it's very appreciated. This is incredible. So, yeah. So, okay. When you were growing up, let's say 8-year-old, Adam-- you know, you're having a good time doing whatever you like to do-- could you possibly have pictured yourself where you are now? [00:21:08] Dr. Adam Power: No, I don't think so. I mean, I, I. I came from a very small, like, small upbringing and, you know, in my family I had absolutely lovely family members, but they really, apart from my aunt, they weren't overly educated. And so I really didn't know what it took to be successful in life, really. I had work ethic from my parents, that's for sure. And so that's what they bred into me. And all I knew is that I was gonna work as hard as I could, and I figured that as long as I keep working-- and I was lucky to have some brains as well-- then I figured things would fall into place. They honestly haven't fallen into place exactly how I pictured them as I grew older and what it would look like. But I'm certainly thankful for where I am right now, and what is the next five years or 10 years gonna look like? I have no idea. And I guess I just don't even picture it. I have goals, but I also know that those goals change depending on circumstances. And you need, as I'm growing into middle age-- I think I'm beyond middle age now-- I'm thinking about midlife crisis and things like that. I get into philosophy and there's like telic and atelic things and so, it's sounds, again, it's about the path and the journey. It's not about the ultimate goal because, having reached a lot of these successes, that good feeling lasts for maybe a day or half a day. And you think you know, I spent all these years coming with the, with our device, getting our device to market and getting FDA approval and like, oh my gosh, like, you'd think, I'd feel so great about that. And it did. It felt great, but you wake up the next day and you gotta keep going. So you have to enjoy the journey and that's really what it's the wisdom that comes with age is trying to enjoy the journey as much as possible and not focus too much beyond that. [00:23:09] Lindsey Dinneen: Yeah. Yeah, and I think that's really good advice too, in that it is because the daily life isn't usually all the celebration and successes. I mean, that does happen and those are good moments, but because the vast majority of our life is spent on the journey component of it, and going through those peaks and valleys, it is important to find something you love and feel that you can make an impact in. So I'm so thankful that this is what you've chosen to do. So pivoting the conversation a little bit just for fun, imagine that you're to be offered a million dollars to teach a masterclass on anything you want. Could be within your industry, but it doesn't have to be. What would you choose to teach? [00:23:55] Dr. Adam Power: And would that mean that I was an expert in it? [00:23:58] Lindsey Dinneen: Well, certainly if you're getting paid a million dollars, somebody has decided you aren't an expert at it. How about that? [00:24:05] Dr. Adam Power: Okay. Well. Can I pretend like I'm an expert in it? There's something that I really love, but I'm not I'm probably not an expert in it. It would be, I would teach a masterclass in DJing. Isn't that strange? I know it's so random. [00:24:21] Lindsey Dinneen: Oh my goodness! Tell me more! [00:24:23] Dr. Adam Power: Well, I mean, I love music. I've, I grew up playing lots of sports and never was involved in music. And, and I've always appreciated music and art, but I was never able to do it. And, you know, growing up I did love sort of all types of music and then even electronic music and it just somehow talked to me. So I started DJing electronic music basically when I was around med school and have always loved it now, and when I was over in England, I DJ'ed on the campus radio and also DJ'd in a club. It was really fun and it sounds pretty silly to be talking about this when I have these other things that are on the go. But honestly, being able to share space with other human beings these days, and actually having a good time and having it not be stressful and having it be only, you know, everybody's wishing others to have a good time. There's not many people that go out sort of dancing into electronic music that are thinking bad things about other people. Really they're just out for a good time. And so being able to steer that whole music and scene is pretty awesome. And I do love it. And I don't DJ as much as I used to, but I still do different events, usually Christmas parties for the operating room. I'll do the typically wedding sort of DJ, but then they always, 'cause they know me, they let me do an hour long electronic set, which is like hardcore electronic. But then I go back to the regular stuff. But I would want to teach a masterclass in DJing. [00:25:56] Lindsey Dinneen: That is awesome. How exciting. Oh my gosh, I love that. And I think you're right. Music brings us together and it's a wonderful way to, to share a little bit of joy. [00:26:07] Dr. Adam Power: Yeah. [00:26:08] Lindsey Dinneen: Yeah. Okay. And then how do you wish to be remembered after you leave this world? [00:26:15] Dr. Adam Power: I, so number one is I don't, again, with my midlife crisis, I've actually been trying to eliminate my ego as much as possible. And so when people talk about legacy, it actually gives me the hives these days to be quite honest, because I don't like that because I think you're focused a lot on yourself. In my opinion, a lot of legacy is all about you. The way that I would wanna be remembered, though, is truly that I was kind and compassionate to everyone that I met, and that I stood for something, and that I left the world a better place. [00:26:57] Lindsey Dinneen: Yeah, those are wonderful things to want to be remembered for, absolutely. And then final question, what is one thing that makes you smile every time you see or think about it? [00:27:09] Dr. Adam Power: My kids. My son Kai and my daughter Saoirse. They are the light of my life. And I, you would think that with how busy I am ,you know, those things would deprioritize, but they truly are the one thing in my life that makes me smile when I get up in the morning. [00:27:30] Lindsey Dinneen: Oh, that's wonderful. Well, that is absolutely incredible. I loved getting to meet you and speak with you a little bit today. Thank you so much for sharing about your journey. Thank you for sharing about your incredible device and your bits of wisdom along the way. The idea of we've gotta enjoy the experience, the path, the journey. And I just really appreciate you spending some time with us. So thank you for everything you're doing to change lives for a better world. [00:27:59] Dr. Adam Power: Oh, well, thank you for giving me the opportunity to speak with you. It was absolutely lovely chatting with you today. [00:28:05] Lindsey Dinneen: Wonderful. Well, thank you again so much. Thank you also to listeners who are tuning in, and if you're as inspired as I am, I would love it if you would share this episode with a colleague or two and we'll catch you next time. [00:28:20] Ben Trombold: The Leading Difference is brought to you by Velentium. Velentium is a full-service CDMO with 100% in-house capability to design, develop, and manufacture medical devices from class two wearables to class three active implantable medical devices. Velentium specializes in active implantables, leads, programmers, and accessories across a wide range of indications, such as neuromodulation, deep brain stimulation, cardiac management, and diabetes management. Velentium's core competencies include electrical, firmware, and mechanical design, mobile apps, embedded cybersecurity, human factors and usability, automated test systems, systems engineering, and contract manufacturing. Velentium works with clients worldwide, from startups seeking funding to established Fortune 100 companies. Visit velentium.com to explore your next step in medical device development.
A recent study from the Mayo Clinic explores the rise in heart attacks among young adults, focusing on nontraditional causes such as spontaneous coronary artery dissection.SCAD is a condition where the artery in the heart suddenly develops a tear or blood forms around the outside of the artery, leading to a heart attack without cholesterol buildup. This condition is nearly six times more common in women than men and often affects younger, otherwise healthy women.SCAD causes 1 in 10 heart attacks in women under age 65. Intense exercise can trigger the condition, but it can also happen unexpectedly.The study aims to raise awareness about these nontraditional causes of heart attacks, which often happen without high cholesterol and other common risk factors. It is important to recognize these symptoms to prevent misdiagnosis.Anyone experiencing chest pain should seek medical attention, as heart attacks can happen in people without traditional risk factors. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Host: Darryl S. Chutka, M.D. Guests: Haraldur Bjarnason, M.D.; and Megha M. Tollefson, M.D. Vascular malformations are anomalies of vessels that can cause a variety of potentially serious health problems depending on their type, location, and size. They may involve arterial, venous or lymphatic vessels. They're often progressive and may enlarge over time. They're best diagnosed with one or more imaging studies and the treatment depends on the type of vascular malformation. Management usually requires a multi-disciplinary approach in order to be most effective. What are the most common types of vascular malformations? What organs are typically involved? What are some of the more serious medical complications they may cause and how should we manage them? The topic for this podcast is “Vascular Malformations” and these are questions I'll be asking my guests, Haraldur Bjarnason, M.D., an interventional and vascular radiologist and Megha M. Tollefson, M.D., a dermatologist, both from the Mayo Clinic. Mayo Clinic Talks: Vascular Medicine Series | Mayo Clinic School of Continuous Professional Development Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts
The National Interscholastic Athletic Administrators Association (NIAAA) and AD Insider have partnered up to showcase specific, important topics for this upcoming school year, designed to help your athletic department excel. Join us for multiple episodes of the NIAAA Workshop Series! Episode #1, presented by Concordia University Irvine: When Seconds Count: EAPs in School SportsAED Awareness & Access - Why they're critical, how to keep them accessible, and key use basics.Distribution Programs - Opportunities schools can leverage to improve emergency preparedness.Albuterol Availability - The importance of having quick access for asthma emergencies and current practices in schools.Catastrophic Injury Data - Statistics by sport and position, plus an overview of state-specific laws.Legal Responsibilities - Understanding the obligations and liabilities athletic departments must be aware of. Workshop Host and Featured Experts:Host: Becky Moran, CMAA: Associate Executive Director - National Interscholastic Athletic Administrators Association (NIAAA)Kristen L. Kucera, PhD, MSPH, ATC, LAT - Professor - Exercise and Sport Science, Director - National Center for Catastrophic Sport Injury Research -- University of North Carolina Chapel HillDr. Neha Raukar, MD, MS, FACEP, CAQSM - Physician & Vice Chair at Mayo Clinic, Emergency & Sports Medicine Specialist, 20+ Years of Elite Athlete Care The NIAAA champions the profession of athletic administration through educational opportunities, advocating ethics, developing leaders, and fostering community. Find more information on their website here: niaaa.org.Support the show
In this episode, we give a wrap-up of late-breaking clinical science presented at the ESC Congress 2025 in Madrid. First, David Berg presents the DAPA ACT HF-TIMI 68 trial, reporting on dapagliflozin in patients hospitalized for acute heart failure, along with a meta-analysis of SGLT2 inhibitors in this setting. Next, Javed Butler highlights results of the VICTOR trial, a large phase 3 study of vericiguat in chronic heart failure with reduced ejection fraction. Then, Andre Zimerman discusses the PhysioSync-HF trial, comparing conduction system pacing with biventricular resynchronization therapy in patients with HFrEF. Finally, Kieran Docherty shares insights from a community-based study on the benefits of early initiation of disease-modifying therapy in suspected heart failure. Additional information: Topic 1: With Gregorio Tersalvi, Mayo Clinic, Rochester, MN - USA, David Berg, Brigham and Women's Hospital, Boston - USA and Novi Yanti Sari, Siloam Hospitals Group, Jakarta - Indonesia Results paper: Dapagliflozin in Patients Hospitalized for Heart Failure: Primary Results of the DAPA ACT HF-TIMI 68 Randomized Clinical Trial and Meta-Analysis of Sodium-Glucose Cotransporter-2 Inhibitors in Patients Hospitalized for Heart Failure Replay ESC Congress Hot Line: https://esc365.escardio.org/presentation/312142 Circulation. 2025 Aug 29. doi: 10.1161/CIRCULATIONAHA.125.076575. Topic 2: With Javed Butler, Baylor Scott & White Health, Dallas - USA and Henrike Arfsten, Medical University of Vienna, Vienna - Austria Results papers: Vericiguat in patients with chronic heart failure and reduced ejection fraction (VICTOR): a double-blind, placebo-controlled, randomised, phase 3 trial Lancet. 2025 Replay ESC Congress hotline: https://esc365.escardio.org/presentation/312148 doi: 10.1016/S0140-6736(25)01665-4. Vericiguat for patients with heart failure and reduced ejection fraction across the risk spectrum: an individual participant data analysis of the VICTORIA and VICTOR trials Lancet. 2025 Aug 29:S0140-6736(25)01682-4. doi: 10.1016/S0140-6736(25)01682-4. Topic 3: With Andre Zimerman, Hospital Moinhos De Vento, Porto Alegre - Brazil and Floran Sahiti, University Hospital of Wurzburg, Wurzburg - Germany Methods paper: Conduction system pacing vs biventricular resynchronization in heart failure with reduced ejection fraction and left bundle branch block: Rationale and design of the PhysioSync-HF Trial Am Heart J. 2025 Dec:290:38-45. Replay ESC Congress: https://esc365.escardio.org/session/50327 doi: 10.1016/j.ahj.2025.06.002. Topic 3: With Kieran Docherty, University of Glasgow, Glasgow - UK and Jolie Bruno, Inserm UMR-S942, Paris - France Results paper: Benefit of early initiation of disease-modifying therapy in community-based patients with suspected heart failure Eur Heart J. 2025 Aug 29:ehaf675. doi: 10.1093/eurheartj/ehaf675. This 2025 HFA Cardio Talk podcast series is supported by Bayer AG in the form of an unrestricted financial support. The discussion has not been influenced in any way by its sponsor.
This week, Dr. Kahn reports on a new Mayo Clinic study on the relationship between chronic insomnia and accelerated brain aging in a group of study subjects who had advanced brain testing over time. He suggests 20 tips for better sleep and a bonus 21st: cognitive behavioral therapy for insomnia (CBT-I). Additional topics include heart disease remaining the #1 cause of death, TMAO and cognitive impairment, ATTR-cardiomyopathy, childhood blood pressure and future heart disease, niacin and optimal liver health, and the relationship between heart diseases like atrial fibrillation and cognitive decline. Thanks to igennus.com and the discount code DrKahn. Dr. Kahn will be leading a group Fasting Mimicking Diet starting 10/5/25. Order your PROLON kit (Next Gen) at www.prolonlife.com/drkahn.
Host: Darryl S. Chutka, M.D. Guests: Sam Farres, M.D.; and Ryan A. Meverden, PA-C Thoracic outlet syndromes is a great masquerader and often mistaken for a variety of other health conditions including cervical radiculopathy, carpal tunnel syndrome, rotator cuff injury or even multiple sclerosis. It has several causes which account for the variety of its clinical presentations. Because of this, the diagnosis is commonly delayed or diagnosed incorrectly. Yet, it's crucial to establish an early and accurate diagnosis as this can prevent potential progression of neurologic damage or in some cases life-threatening vascular complications. It also prevents unnecessary treatments and inappropriate interventions. The topic for this podcast is “Thoracic Outlet Syndrome” and my guests include Ryan Meverden, PA-C, a physician assistant in the Vascular Center at the Rochester campus of the Mayo Clinic and Sam Farres, M.D., Division Chair of Vascular Surgery at the Florida campus of the Mayo Clinic. As we discuss thoracic outlet syndrome, we'll review the variety of presenting symptoms, potential complications, appropriate tests to evaluate patients and effective management strategies. Mayo Clinic Talks: Vascular Medicine Series | Mayo Clinic School of Continuous Professional Development Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts
When radiology meets surgery, endometriosis care becomes more precise, personalized, and proactive. In this BackTable OBGYN Brief, host Dr. Mark Hoffman is joined by Dr. Wendaline VanBuren, an associate professor of radiology at Mayo Clinic, and Dr. Tatnai Burnett, a minimally invasive GYN surgeon at Mayo Clinic, to discuss the complexities of diagnosing and managing endometriosis. The discussion covers the roles of advanced imaging techniques like MRI and ultrasound, the importance of pre-surgical planning, and the need for multidisciplinary collaboration. They share their approach to managing symptomatic and asymptomatic patients, the use of hormonal treatments, and the significance of monitoring potential malignant transformations in endometrioma cases. The episode underscores the critical role of imaging in planning effective surgical interventions for patients while highlighting the progression of endometriosis management protocols. TIMESTAMPS 00:00 - Introduction 01:07 - Discussing Endometriosis Management 02:18 - Imaging Techniques and Their Importance 04:24 - Interdisciplinary Collaboration 05:40 - Advanced Imaging Protocols 08:12 - Monitoring and Follow-Up Strategies 08:50 - Concerns About Malignancy 11:04 - Future Directions CHECK OUT THE FULL EPISODE OBGYN Ep. 69 https://www.backtable.com/shows/obgyn/podcasts/69/imaging-protocols-to-guide-endometriosis-treatment
Statin Myopathy Guest: Stephen Kopecky, M.D. Host: Sharonne Hayes, M.D. Statins are very helpful to lower LDL cholesterol and subsequently lower cardiovascular risk. Studies of statins have excluded subjects that are statin intolerant which is usually due to muscle symptoms such as aches, called myalgias, muscle cramps, or weakness. One of the most significant predictors of statin intolerance is the dose -the higher the dose, the more likely to develop intolerance. Accepted in recommended ways to minimize intolerance is to use generic combination therapy with a lower dose statin and a cholesterol absorption inhibiting agent such as ezetimibe. Newer agents such as PCS K 9 inhibitors and inclisiran, both given subQ, and bempedoic acid may reduce statin muscle symptoms. Topics Discussed: Is any statin more or less likely to cause statin associated muscle symptoms? Are there any protective medications that can minimize statin myalgias? What newer non-statin agents have been shown to reduce risk of myalgias? How is treating high cholesterol levels becoming more like treating blood pressure? Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode. Podcast episode transcript found here.
Nick Stageberg is the CEO of Black Swan Real Estate and a former tech entrepreneur who scaled a $13M startup to a $100M exit. He later led 13 engineering teams at Mayo Clinic before building a thriving real estate portfolio with his wife, Elaine. Today Nick leverages his tech-driven approach to give Black Swan a distinct edge in the multifamily industry. Here's some of the topics we covered: From Tech Career to Real Estate Freedom How to Turn Setbacks Into Your Greatest Wins Warren Buffet's Surprising Take on D Class Properties Using Real Estate Profits to Create Lasting Impact Must-Know Tips for First-Time Investors How to Land a Mentor Without Spending a Dime Why Real Estate Beats Even the Highest-Paying W2 Job To find out more about partnering or investing in a multifamily deal: Text Partner to 72345 or email Partner@RodKhleif.com For more about Rod and his real estate investing journey go to www.rodkhleif.com
Dr. Jonathan Morris is the Executive Medical Director of Immersive and Experiential Learning at the Mayo Clinic. He is also the Medical Director of Biomedical and Scientific Visualization and helped set up their Anatomic Modeling Unit nearly 19 years ago. With over 23 years at the Mayo Clinic, much of it working with 3D printing, Dr. Morris has a lot of experience with the technology. He's not always a happy 3D printing user, but here he passionately explains what it can do for patients and doctors. We also talk about how 3D printed models gained a foothold at Mayo, how they grew in use, and how they're used today. We talk about Mayo Clinic's pursuit of 3D printing implants in the hospital and other pioneering work in a must-listen episode for anyone in the medical field. This episode of the 3DPOD is brought to you by Würth Additive Group, industry leaders in digital inventory and physical supply chain solutions. From factory floors to frontline operations, Würth Additive helps manufacturers streamline sourcing and stay production-ready with 3D printing, on-demand parts, and smart inventory strategies.
Senescent cells were supposed to be the "easy" target in aging research—clear them out and extend healthspan. But new research reveals the field is far more complex than anyone imagined, with major clinical trial setbacks forcing scientists to completely rethink their approach.Some links are affiliate links so we will earn a commission when they are used to purchase products.In this conversation with Dr. Paul Robbins from the University of Minnesota, we explore the evolving world of senescent cell research and senolytics—drugs designed to clear "zombie" cells from our bodies. Dr. Robbins reveals how recent research shows senescence is far more complex than expected, with different types arising from different stresses. We discuss why Unity Biotech's trials failed, mixed results from fisetin studies, and surprising positive signals from Mayo Clinic trials in patients with high senescent cell burden. He explains why future treatments will require personalized cocktails of different senolytics, the potential of alternative approaches, and why he remains optimistic despite setbacks. Dr. Robbins also shares insights into next-generation compounds his lab is developing and hints at positive clinical trial results coming soon.
Ready to not only live longer, but to live BETTER? In this episode, I'm joined by longevity expert Dr. Shah, where we dive into his journey in functional medicine and how he's dedicated his career to educating patients on optimizing their healthspan. Dr. Shah breaks down the four key pillars of longevity that he uses in his practice to help his patients combat disease and illness to live better, more fulfilling lives. You'll also learn simple, impactful lifestyle hacks—like eliminating ultra-processed foods, prioritizing self-care strategies, weaving in daily movement, and understanding how to balance stress and recovery. From understanding crucial biomarkers to track in midlife, to demystifying peptides at a cellular level– Dr. Shah is here to offer science-backed tips that will truly move the needle in helping you feel your best for years to come. Tune in here! Darshan Shah, MD Dr. Darshan Shah is a health and wellness specialist, board-certified surgeon, published author, and founder of Next Health, the world's first and largest Health Optimization and Longevity clinic. As a Longevity Medicine specialist, he's worked with thousands of patients to help optimize their well-being and extend their healthspan. Dr. Shah earned his medical degree at the age of 21, becoming one of the youngest doctors in the US. He continued his training at the Mayo Clinic, opened medical/surgical centers throughout California, started four other companies in the Health and Wellness space, and has published a book. Dr. Shah's passion is educating people on the topics of adding healthspan to your lifespan. IN THIS EPISODE Dr. Shah's journey to becoming a longevity expert The importance of finding time in a busy schedule for self-care All about Dr. Shah's functional medicine company, Next Health Simple ways to add movement to your day Defining longevity and how to optimize your life span The 4 key pillars of longevity Key biomarkers of health to track in your 40s and beyond How your gut microbiome impacts your overall health What are peptides, and how can they benefit you? Dr. Shah's top lifestyle tips to truly move the needle for your health QUOTES “The elimination of ultra-processed food will move the needle more than anything else you could potentially put into your body.” “Now people have access to their data, but step two is having personal responsibility to understand what that data means, why it's important, and following it yourself.” “There's a balance that our biology needs to live under. It needs to have some stress, and it needs to have time to relax. It needs to have heavy exercise, but it also needs to have just light movement… You have to find where that balance lies in your own system and it's always going to be changing. And you're not going to know this until you check some of these biomarkers.” RESOURCES MENTIONED
Host: Darryl S. Chutka, M.D. Guest: Stan Henkin, M.D. Peripheral arterial disease is a manifestation of atherosclerosis and becomes more common with advancing age. In its early stages, it can be quite difficult to diagnose. Although claudication is the most classic symptom, many remain asymptomatic, especially if they have limited ability to ambulate. Although risk factor modification is important in disease management, overall treatment options have been somewhat disappointing. How can we diagnose PAD early and are there advantages in recognizing the disease in an early stage? What are the best ways to establish a diagnosis and what treatment options do we have available? Our topic for this podcast is “Peripheral Arterial Disease” and these are questions I'll asking my guest, Stan Henkin, M.D., a vascular medicine specialist from the Department of Cardiovascular Medicine at the Mayo Clinic. Mayo Clinic Talks: Vascular Medicine Series | Mayo Clinic School of Continuous Professional Development Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts
Published September 11, 2025 In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, and William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, discuss troublesome organisms making headlines. Together, they explore:Vibrio vulnificus (01:09): How people get this “flesh-eating” bacteria, how it affects patients, and a recent case that brought it into the spotlight.Staying safe (03:44): Discover when to seek medical attention and how knowledge can protect you as Vibrio vulnificus bacterium becomes more prevalent. New World screwworm (06:50): How this parasitic infection damages human tissue, how it was previously eradicated, and why it's making the news again. ABCs of protection (12:16): A simple reminder to avoid exposure, use bug spray, and wear protective clothing to shield against hazardous organisms.Laboratory as first line of defense (13:34): Laboratorians have a critical role in identification and monitoring broader trends when these types of cases arise. ResourcesA-Zs for prevention and exposure risks
Alzheimer's disease and related dementias now affect more than 55 million people worldwide — and that number is growing fast. But is cognitive decline inevitable? Not anymore.In this episode, Jay Croft speaks with Angela Lunde, a 24-year Mayo Clinic veteran and co-author of the newly revised Mayo Clinic on Alzheimer's Disease and Other Dementias. Angela shares powerful insights on how lifestyle choices, early detection, and caregiver support are reshaping the landscape of brain health.You'll learn:How lifestyle factors like exercise and social connection impact brain functionThe latest in dementia risk reduction, including the POINTER study's findingsWhat new treatments are showing promise — and what still isn't possibleThe emotional reality for caregivers, and how they can build resilienceHow fitness and wellness pros can guide clients over 50 toward better brain healthThis conversation is both deeply informative and inspiring for anyone concerned about aging, dementia, and long-term wellbeing.
Join us for an in-depth conversation with Dr. Aahd Kubbara, a practicing pulmonologist, intensivist, and Assistant Professor of Medicine at the University of Minnesota Medical Center. Dr. Kubbara specializes in pulmonary, allergy, critical care, and sleep medicine, with advanced expertise in interstitial lung disease, asthma, and targeted biological therapies. In this episode, we explore the complexities of lung health and the latest strategies for preventing and managing chronic respiratory conditions: · How inflammatory lung diseases can cause long-term scarring. · The consequences of untreated or poorly managed asthma over time. · What pulmonary fibrosis is and the most effective approaches to treatment. · The risks of normalizing chronic respiratory symptoms. · Seasonal asthma triggers and how to reduce their impact. With years of experience at the Mayo Clinic and University of Nevada, as well as community pulmonary care practice, Dr. Kubbara offers insights into cutting-edge therapies, personalized medicine, and preventive strategies to maintain lung health. Learn more about Dr. Kubbara and his work in pulmonary medicine here! Episode also available on Apple Podcasts: https://apple.co/38oMlMr Keep up with Dr. Aahd Kubbara socials here: Instagram: https://www.instagram.com/aahd_kubbara/?hl=en X : https://x.com/aahdkubbara
Send us a textImagine visiting your gastroenterologist and feeling comfortable enough to discuss every aspect of how IBD affects your life—including your sexual health and practices. For many patients, particularly those in the LGBTQI+ community, this remains an elusive dream rather than reality.Dr. Victor Chedid, gastroenterologist and director of Mayo Clinic's Pride Clinic, joins Bowel Moments to tackle this crucial gap in IBD care. With disarming honesty and clinical expertise, he reveals why addressing sexuality isn't just about inclusivity—it's about providing complete medical care. When 95% of providers believe discussing sexual health is important but only 27% actually do it, patients suffer in silence with questions that directly impact their quality of life.The conversation dives deep into practical approaches for both patients and providers. Dr. Chedid shares his framework for discussing sexual practices with patients, from the straightforward question "What do you do for sex?" to navigating complex conversations around surgical interventions like J-pouch formation. For transgender patients, he unpacks recent research on gender-affirming hormones and IBD, emphasizing that life-saving gender-affirming care should never be withheld due to IBD concerns.Perhaps most compelling is Dr. Chedid's perspective on cultural humility and intersectionality. Each patient's experience is shaped by multiple overlapping identities—their sexuality, gender, race, nationality, and more. Rather than making assumptions, he advocates for providers to "leave their biases at the door" and approach each person's unique situation with curiosity and respect."People living with IBD are the experts of their own bodies," Dr. Chedid reminds us in his powerful closing thoughts. "When they say something feels off, it's not a guess—it's lived experience." This principle forms the foundation of truly inclusive care—care that sees patients as whole people deserving of dignity, understanding, and comprehensive treatment.Ready to advocate for more inclusive IBD care? Share this episode with your healthcare team and join the conversation about creating safe spaces for everyone in our community.Links: AGA's Pride Month Provider Spotlight on Dr. ChedidDr. Chedid talking about forming the IBD Pride Clinic"Your Top 6 Questions Answered by Dr. Victor Chedid" -A Program Dedicated to IBD Patients from the LGBTQIA+ Community- Crohn's & Colitis Foundation- USALet's get social!!Follow us on Instagram!Follow us on Facebook!Follow us on Twitter!
Host: Darryl S. Chutka, M.D. Guest: Ana I. Casanegra, M.D., M.S. For many decades, we really only had one option for providing chronic anticoagulation, warfarin. We learned how to manage the many drug and food interactions, frequently changing the warfarin dose as we tried to keep our patients in therapeutic range. Now we have a variety of choices with the direct-acting oral anticoagulants, or DOAC's. How do the newer agents compare to warfarin in effectiveness? Are they really safer than warfarin? Do they ever require any monitoring? What's the latest on reversing the anticoagulant effect? I'll be discussing these topics and more with my guest, Ana I. Casanegra, M.D., M.S., a vascular medicine specialist at the Mayo Clinic. The topic for this podcast is “How to Choose Your Anticoagulant”. Mayo Clinic Talks: Vascular Medicine Series | Mayo Clinic School of Continuous Professional Development Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts
Claim your complimentary gift of my exclusive mini weight care guide today!Link: Weight Care Guide — Dr. Francavilla Show (thedrfrancavillashow.com)Ever wonder why the same weight loss plan can work wonders for one person but barely move the needle for another?Or why some people respond really well to medications like Wegovy, while others struggle with side effects or see minimal results? That's exactly what precision obesity medicine aims to answer—and today, we're diving into it with one of the world's leading experts.We're joined by Dr. Andres Acosta, a true pioneer in obesity medicine and the creator of the obesity phenotypes concept. He's board-certified in internal medicine, gastroenterology, hepatology, obesity medicine, and nutrition. At the Mayo Clinic, he co-directs the Nutrition and Obesity Research Program and leads the Precision Medicine for Obesity program, focusing on matching the right treatment to the right patient with fewer side effects.Dr. Acosta's research is supported by the National Institutes of Health, with more than 145 peer-reviewed papers in top journals. His work has been featured in The New York Times, TIME, CNN, and NPR, and he's earned “40 Under 40” recognition and co-founded Genomic Sciences—just a glimpse of his many accomplishments.If you've ever felt frustrated by trial-and-error weight loss or wondered if there's a more scientific way to find what actually works for you, you're going to want to hear what Dr. Acosta shares in this episode.Connect with Dr. Acosta:Mayo Clinic: mayu.eduPhenomix Sciences: WebsiteConnect with me:Instagram: doctorfrancavillaFacebook: Help Your Patients Lose Weight with Dr. FrancavillaWebsite: Dr. Francavilla ShowYoutube: The Doctor Francavilla ShowGLP Strong: glpstrong.com
Richard Gearhart and Elizabeth Gearhart, co-hosts of Passage to Profit Show have this discussion with leadership and scaling coach Kenny Lange, Jen Rafferty from Empowered Educator and Whitney Dueñas Richardson from Global Sprouts. In this episode, leadership and scaling coach Kenny Lange, reveals why so many founders unknowingly sacrifice their soul, their people, and their purpose in the pursuit of growth—and how to avoid it. If you've ever felt like success requires becoming someone you're not, this conversation will challenge and inspire you to lead differently. Read more at: https://kennylange.com/ Jen Rafferty is the founder of Empowered Educator, a research-based professional development program dedicated to supporting teacher and school leader well-being. Empowered Educator focuses on the social and emotional well-being of adults in schools, leveraging concepts of mindset, emotional intelligence, and cognitive neuroscience. Read more at: https://empowerededucator.com/ Whitney Dueñas Richardson is the founder of Global Sprouts, a children's education brand with a focus on cultural learning, creativity, and language exposure. A multicultural mom with CHamoru and Dutch roots, Whitney built her business while navigating postpartum recovery, the loss of her home to Hurricane Helene, and the challenges of starting over from scratch. Read more at: https://www.globalsprouts.com/ Whether you're a seasoned entrepreneur, a startup, an inventor, an innovator, a small business or just starting your entrepreneurial journey, tune into Passage to Profit Show for compelling discussions, real-life examples, and expert advice on entrepreneurship, intellectual property, trademarks and more. Visit https://passagetoprofitshow.com/ for the latest updates and episodes. Chapters (00:00:00) - Starting a Business(00:00:30) - Passage to Profit(00:01:38) - What Was I Thinking?(00:07:05) - Tim Ferriss: Sacrificial Souls(00:11:34) - What's Your Most Challenging Leadership Situation?(00:16:01) - Hiring Processes: Design the Head and Fit It(00:17:34) - What Is The Secret to Scaling a Company?(00:19:15) - Is there a lot of simplification that's required in order to(00:21:12) - The Investment Value of Gold(00:22:14) - The Cruise Hotline(00:23:12) - Lead to Scale: How to Avoid Burnout(00:25:58) - The Enneagram: How to Lead With Self-awareness(00:31:49) - Intellectual Property News(00:34:11) - Kenny Lang on Netflix's Copyright Lawsuit(00:39:24) - Medguard CareWatch(00:42:07) - What's Happening in the Studio?(00:44:18) - Mayo Clinic's AI System to Identify Surgery Site Infections(00:46:19) - Empowered Educator(00:47:36) - How to Talk to Yourself About Burnout(00:52:34) - Burnout and the Regulation of the Nervous System(00:55:30) - How to Recover From Burnout Through Emotional Intelligence(00:58:48) - Teachers and the Future of AI(01:02:44) - The Right Way to Teach AI(01:04:06) - Whitney Duanes Richardson on Global Sprouts(01:07:21) - Have You Got What it Takes to Teach Culture?(01:11:11) - Passage to Profit(01:12:23) - Passage to Profit: A Mother's Phone(01:13:39) - Secret to Success: The Entrepreneurial Mind(01:14:55) - Richard Gearhart on Self-Care(01:16:46) - P2P