Podcasts about Mayo Clinic

Today's guest is Dr. Christopher Camp, a board-certified orthopaedic surgeon with a deep focus on sports medicine and shoulder and elbow surgery. Since 2019, Dr. Camp has served as the Medical Director, Team Physician, and Director of High Performance for the Minnesota Twins, where he works closely with players, athletic trainers, and front office staff to keep athletes healthy and performing at their best.Beyond the field, Dr. Camp is a leading researcher in the biomechanics of throwing, injury prevention, and surgical innovation. His work is shaping how we understand and treat injuries in overhead athletes—not just in baseball, but across all sports. He also leads the Human Optimization Project at the Mayo Clinic, an initiative focused on maximizing health, performance, and recovery. Listen along as we dive into his unique perspective on athlete care, research, and the evolving relationship between medicine and high performance in professional baseball.For more information about PBATS and athletic training, visit pbats.com.

Special guest & performance coach Dr. Cindra Kamphoff explores with Megan and Brad mental practices to thrive in demanding environments like IT and Cybersecurity fields.Through her work with companies like Verizon, the Minnesota Vikings, and Mayo Clinic, Cindra unpacks tools for resilience, confidence building, and facing setbacks. From the "Learn, Burn, Return" method to understanding Imposter Syndrome, this conversation prompts action and provides strategies for thriving under pressure that can apply to anyone. Enjoy this episode of Unsecurity! -- We want to hear from you! Send your suggestions, comments, and questions to unsecurity@frsecure.com. LinkedIn: https://www.linkedin.com/company/frsecure/ Instagram: https://www.instagram.com/frsecureofficial/ Facebook: https://www.facebook.com/frsecure/ BlueSky: https://bsky.app/profile/frsecure.bsky.social About FRSecure: https://frsecure.com/ FRSecure is a mission-driven information security consultancy headquartered in Minneapolis, MN. Our team of experts is constantly developing solutions and training to assist clients in improving the measurable fundamentals of their information security programs. These fundamentals are lacking in our industry, and while progress is being made, we can't do it alone. Whether you're wondering where to start, or looking for a team of experts to collaborate with you, we are ready to serve.

Host: Darryl S. Chutka, M.D. Guest: John W. Wilson, M.D. Tuberculosis remains a significant health concern. Globally, in 2023, an estimated 10 million individuals developed active tuberculosis and over one million died of the disease. In the U.S., just under 10, 000 individuals in the U.S. were diagnosed with TB, representing an increase over 2022. While tuberculosis remains a treatable disease, it's important to suspect and recognize those who may have it. A class 5 tuberculosis case is part of a TB classification system and refers to a suspected tuberculosis infection that requires further investigation. Symptoms may or may not be present and these patients may have an active TB case that could be contagious. This podcast is about class 5 tuberculosis cases, and my guest is infectious disease specialist, John W. Wilson, M.D., from the Mayo Clinic. Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts

Joseph Yao, M.D., explains how Mayo Clinic Laboratories' new quantitative assay (Mayo ID: ADVQU) goes beyond qualitative testing to evaluate transplant patients for adenovirus infection. Adenovirus can cause life-threatening disease in immunocompromised transplant patients, especially children.(01:14)Could you give us a brief overview of this assay? (02:06)Can you explain the differences of the qualitative and quantitative methods and why we made the change to a quantitative adenovirus method? (04:00)When is this test typically ordered for transplant patients? Is it used throughout their treatment? (06:56)Could an immunocompromised person be unknowingly infected? (07:31)Is our quantitative method approved for pediatric patients? (08:00)How are the test results used to treat patients?(10:36)What other infections might providers consider alongside adeovirus?

Why Pulmonary Hypertension Isn't Just a Lung ProblemCardiologist Dr. Lisa Mielniczuk from the Mayo Clinic pulls back the curtain on one of the most common — yet misunderstood — forms of pulmonary hypertension: the kind caused by left heart disease. In this episode, she explains why it's time we stop thinking of PH as a rare condition. Learn more about pulmonary hypertension trials at www.phaware.global/clinicaltrials. Follow us on social @phaware Engage for a cure: www.phaware.global/donate #phaware Share your story: info@phaware.com @phacanada  #phawareMD @mayoclinic @teamphhope

Electrophysiology Considerations in Oncology Patients   Guest: Nicholas Tan, M.D., M.S. Host: Anthony H. Kashou, M.D.   In today's episode of ECG Making Waves, Dr. Anthony Kashou interviews Dr. Nicholas Tan on how clinicians should consider electrophysiology in the patient with cancer. After listening to this episode, learners will understand the relationship between cancer and heart rhythm disorders, as well as begin to appreciate how cancer and arrhythmia treatments can interact.   Topics Discussed: Why are arrhythmias even relevant in cancer patients? What are some key arrhythmias associated with cancer or their therapies? What is a general approach towards managing arrhythmias in cancer patients? Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode. Podcast episode transcript found here.

When bringing people to the edge of death is your day job. Guest: Adam Richman, perfusionist at the Mayo Clinic⁠ and Unexplainable listener. For show transcripts, go to ⁠⁠⁠⁠⁠⁠⁠⁠vox.com/unxtranscripts⁠⁠⁠⁠⁠⁠⁠⁠ For more, go to ⁠⁠⁠⁠⁠⁠⁠⁠vox.com/unexplainable⁠⁠⁠⁠⁠⁠⁠⁠ And please email us! ⁠⁠unexplainable@vox.com⁠⁠ We read every email. Support Unexplainable (and get ad-free episodes) by becoming a Vox Member today: ⁠⁠⁠⁠⁠⁠⁠⁠vox.com/members⁠⁠⁠ Help us plan for the future of Unexplainable by filling out a brief survey: ⁠⁠⁠⁠⁠voxmedia.com/survey⁠⁠⁠⁠⁠. Thank you! Learn more about your ad choices. Visit podcastchoices.com/adchoices

Have you heard of longevity medicine? It's next-level healthcare—and Dr. Darshan Shah is one of the pioneers leading the way. In this episode, Dr. Shah shares how he's transforming the way we treat women in perimenopause and postmenopause by focusing on real root causes—not just symptom management.  We cover: What he learned about women's health as a surgeon How he approaches menopause differently than most doctors The truth about hormone testing during the transition The real drivers of Alzheimer's, osteoporosis, and heart disease in women Why so many doctors are confused about menopause care Exactly how to empower yourself at your first menopause visit How he uses the Wellness Wheel to individualize care A peek into cutting-edge therapies like Therapeutic Plasma Exchange and NAD+   Darshan Shah, MD, is a health and wellness specialist, board-certified surgeon, published author, entrepreneur, and founder of Next Health, the first, largest and fastest-growing health optimization and longevity clinic. He began his career at an accelerated MD program and earned his medical degree at the age of 21, becoming one of the youngest doctors in the United States. He then continued his training at the Mayo Clinic, and earned his MBA from Harvard Business School in 2015. As a longevity medicine specialist, he has advised thousands of patients on how to optimize their well-being and extend their healthspan and lifespan.    PREVIOUS EPISODE: https://www.drshah.com/extend-podcasts/zora-benhamou Extend Podcast: https://podcasts.apple.com/us/podcast/welcome-to-extend-with-darshan-shah-md/id1773578243?i=1000673875409  Biomarkers list: https://www.drshah.com/biomarkers   Contact Dr. Darshan Shah Website: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd  Email: contact@drshah.com   Give thanks to our sponsors: Qualia senolytics and brain supplements. 15% off with code ZORA here. Try Vitali skincare. 20% off with code ZORA here https://vitaliskincare.com Get Primeadine spermidine by Oxford Healthspan. 15% discount with code ZORA ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Get Mitopure Urolithin A by Timeline. 10% discount with code ZORA at https://timeline.com/zora Try Suji to improve muscle 10% off with code ZORA at TrySuji.com https://trysuji.com Get Magnesium Breakthrough by Bioptimizers. 10% discount with code HACKMYAGE at https://bioptimizers.com/hackmyage Try OneSkin skincare with code ZORA for 15% off https://shareasale.com/r.cfm?b=2685556&u=4476154&m=102446&urllink=&afftrack= Join ⁠⁠⁠Biohacking Menopause⁠⁠⁠ before July 1, 2025 to win free Vitali Skincare! 20% off with code ZORA at VitaliSkincare.com   Join the Hack My Age community on: Facebook Page: ⁠⁠⁠⁠⁠@⁠Hack My Age⁠     Facebook Group: ⁠⁠⁠⁠⁠⁠@⁠Biohacking Menopause⁠⁠⁠⁠⁠⁠ ⁠  Private Women's Only Support Group: https://hackmyage.com/biohacking-menopause-membership/ Instagram: ⁠⁠⁠⁠⁠@⁠HackMyAge⁠    Website: ⁠⁠⁠⁠⁠⁠HackMyAge.com⁠     

In this episode of the VJHemOnc podcast, we are joined by Morie Gertz, MD, MACP, Mayo Clinic, Rochester, MN, a... The post Diagnosing amyloidosis: identifying early signs, appropriate diagnostic tests, and challenges that remain appeared first on VJHemOnc.

Burnout in medicine: When was burnout at its peak for doctors? Why are doctors so burnt out? What causes burnout in health care? Is there a National Burnout Study? Our guest is Michael Tutty, PhD, group vice president of Professional Satisfaction and Practice Sustainability at the American Medical Association. AMA CXO Todd Unger hosts.

Resilience, hope, and the profound power of holistic healing take center stage in this conversation. In this episode, we dive deep into a truly remarkable journey with Dr. Dawn Mussallem, a physician at Mayo Clinic, as she shares her powerful personal battles against stage four cancer, advanced heart failure, and a life-altering heart transplant, all while maintaining an unwavering zest for life and dedication to her patients; you'll hear about her unique insights on nutrition, plant-based diets, and the often-overlooked role of emotional well-being in physical health, including her groundbreaking work in plant protein development and regenerative farming. Through her inspiring story, you'll discover not only her medical expertise but also her profound belief in the human spirit's capacity to overcome adversity, ultimately transitioning "hope to knowing" that everything will be alright.The information presented in Fully Alive is for educational and informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or treatment and before making changes to your health regimen. Guests' opinions are their own and do not necessarily reflect those of the podcast host, production team, or sponsors.Love the show? Subscribe, rate, review, & share! https://www.shellpoint.org/podcast/

Recently, sophisticated myelographic techniques to precisely subtype and localize CSF leaks have been developed and refined. These techniques improve the detection of various types of CSF leaks thereby enabling targeted therapies. In this episode, Katie Grouse, MD, FAAN, speaks with Ajay A. Madhavan, MD, author of the article “Radiographic Evaluation of Spontaneous Intracranial Hypotension” in the Continuum® June 2025 Disorders of CSF Dynamics issue. Dr. Grouse is a Continuum® Audio interviewer and a clinical assistant professor at the University of California San Francisco in San Francisco, California. Dr. Madhavan is assistant professor of radiology at the Mayo Clinic in Rochester, Minnesota. Additional Resources Read the article: Radiographic Evaluation of Spontaneous Intracranial Hypotension Subscribe to Continuum®: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Full episode transcript available here Dr Jones:  This is Dr Lyell Jones, Editor-in-Chief of Continuum. Thank you for listening to Continuum Audio. Be sure to visit the links in the episode notes for information about earning CME, subscribing to the journal, and exclusive access to interviews not featured on the podcast. Dr Grouse:  This is Dr Katie Grouse. Today I'm interviewing Dr Ajay Madhavan about his article on Radiographic Evaluation of Spontaneous Intracranial Hypotension, which he wrote with Dr Levi Chazen. This article appears in the June 2025 Continuum issue on disorders of CSF dynamics. Welcome to the podcast, and please introduce yourself to our audience. Dr Madhavan:  Hi, thanks a lot, Katie. Yeah, so I'm Ajay Madhaven. I'm a neuroradiologist at the Mayo Clinic in Rochester, Minnesota. I did all my training here, so, I've been here for a long time. And I have a lot of interest in spinal CSF leaks, and I do a lot of that work. And so I'm really excited to be talking about this article with you. Dr Grouse:  I'm really excited too. And in fact, it's such a pleasure to have you here talking today on this topic. I know a lot's changed in this field, and I'm sure many of our listeners are really interested in learning about the developments and imaging techniques to improve detection and treatment of CSF leaks, especially since maybe we've learned about this in training. I want to start by asking you what you think is the most important takeaway from your article. Dr Madhavan:  Yeah, that's a great question. I think---and you kind of already alluded to it---I think the main thing is, I hope people recognize that this field has really changed a lot in the last five to ten years, through a lot of multi-institutional collaboration and also collaboration between different specialties. We've learned a lot about different types of spinal CSF leaks, how we can recognize the disease, particularly the types of myelography that we need to be using to accurately localize and treat these leaks. Those are the things that have really evolved in the last five to ten years, and they've really helped us improve these patients' lives. Dr Grouse:  Can you remind us of the different common types of spinal leaks that can cause spontaneous intracranial hypotension? Dr Madhavan:  Yeah, so there are a number of different spinal CSF leaks, types, and I would say the three most common ones that really most people should try to be aware of and cognizant of are: first, ventral dural tears. So those are, like, just physical holes in the dura. And they're usually caused by little bone spurs that come from the vertebral columns. So, they're often patients who have some degenerative changes in their spine. And those are really very common. Another type of spinal CSF leak that we commonly see is a lateral dural tear. So that's like the same thing in a slightly different location. So instead of being in the front, it's off to the side of the dura laterally. And so, it's also just a hole in the dura. And then the third and most recently discovered type of spinal CSF leak is a CSF-venous fistula. So those are direct connections between the subarachnoid space and little paraspinal vein. And it took us a long time to even realize that this was a real pathology. But now that it's been recognized, we've found that this is actually quite common. So those three types of leaks are probably the three most common that we see. And there's certainly others out there, but I would say over 90% of them fall into one of those three categories. Dr Grouse:  That's a great review, thank you. Just as another quick review, as we talk more about this topic, can you remind us of some of the most common or typical brain imaging findings that you'll see in cases of spontaneous intracranial hypotension? Dr Madhavan:  Yeah, absolutely. So, when you do a brain MRI in a patient who has spontaneous intracranial hypotension, you will usually, though not always, see typical brain MRI abnormalities. And I kind of think of those as falling into three different categories. So, the first one I think of is dural enhancement or thickening. So that's enlargement or engorgement of the dura, the pachymeninges, and enhancement on postgadolinium imaging. So, that's kind of the first category. The second is that, when you lose spinal fluid volume, other things often expand to take up the space. So, for example, you can get distension or enlargement of the dural venous sinuses, and sometimes you can also get subdural food collections or hematomas. They can arise spontaneously. And I kind of think of those as, you know, you, you've lost the cerebrospinal fluid volume and something else is kind of filling up the space. And then the third category is called brain sagging. And that's a constellation of findings where the posterior fossa structures and the pituitary gland in the cell have become abnormal because you've lost the fluid that normally cushions those structures and causes them to float up. For example, the brain stem will sag down, the distance between the mammillary body and the ponds may become reduced. The suprasellar cistern space may be reduced such that the optic chiasm becomes very close to the pituitary gland, and the prepontine cistern may also become reduced in size. And there are various measurements that can be used to determine whether something is subtly abnormal. But just generally speaking, those are really the three categories of brain MRI abnormalities you'll see. Dr Grouse:  That was a great review. And of course, I think in many times when we are thinking about or suspecting this diagnosis, we may be lucky to find those imaging findings to reinforce a diagnosis. Because as it turns out, after reading your article, I was really surprised to find out that in as many as 19% of cases we actually see normal brain imaging, which really was a surprise to me, I have to say. And I think that this really encompasses why spontaneous intercranial hypotension is such a difficult diagnosis to make. I think a lot of us struggle with how far to take the workup when, you know, spontaneous intercranial hypotension is clinically suspected, but multiple imaging studies are normal. Do you have any guidance on how to approach these more difficult cases? Dr Madhavan:  So, that's a really good question. And you know, it's- as you can imagine, that's a topic that comes up in most meetings where people discuss this, and it's been a continued challenge. And so, like you said, about 19 or 20% of patients who have this disease can have a, a normal brain MRI. And we've tried to do some work to figure out why that is and how we can identify patients who still have the disease. And I can just provide, I guess, some tips that have helped me in my clinical practice. One thing is, if I ever see a patient with a normal brain MRI where this disease is clinically suspected---for example, maybe they have orthostatic headaches or other very typical symptoms and we don't know why, but their brain MRI is normal---the first thing I do is I try to look back at their old imaging. So many times, these patients who present to us at Mayo, who, when we do their MRI scan here, their brain MRI looks normal… if you really look back at imaging that they've had done elsewhere---maybe even two to three years prior---at the time their symptoms started, they actually had some abnormalities. So, I might see that a patient, two years ago, had dural enhancement that spontaneously resolved; but now they still have symptoms of SIH and they may still have a CSF leak that we can find and treat, but their brain MRI has, for whatever reason, normalized. So, I always start by looking back at old imaging, and I found that to be very helpful. The other thing is, if you see a patient with a normal brain MRI, it's also important to look at their spine MRI because that can provide clues that might suggest that they could still have a spinal CSF leak. And the two things I look for on the spine MRI: one, if there's any extradural CSF. So, spinal fluid outside of where it's supposed to be within the confines of the subarachnoid space. And you know, really, if you see extradural CSF, you know they probably have a spinal fluid leak somewhere. Even if their brain MRI is normal, that just gives you the information that there is a dural tear probably somewhere. And so, in those patients we'll definitely still proceed to myelography or other testing, even if they have a normal brain MRI. And then the last thing I look for is whether or not they have prominent meningeal diverticula. Patients with CSF venous fistulas almost always have one or more prominent diverticula on their spine along the nerve root sleeves. And that's probably because most of these fistulas come from nerve root sleeve diverticula. We don't completely understand the pathogenesis of CSF venous fistulas, but they're clearly associated with meningeal diverticula. So, if I see a patient who has a normal brain MRI, but I see on their spine MRI that they have many meningeal diverticula that are relatively prominent, that makes me more inclined to be a little bit more aggressive in doing myelography to find a CSF leak. And then I look at other demographic features, too. So, for example, elevated BMI and older age are associated with CSF venous fistulas. So, that can help you determine whether or not it's warranted to go on to more advanced imaging, too. So those are all just a variety of different things that we've used to help us. Dr Grouse:  Thank you for sharing that. I wanted to go on to say that, you know, reading your article, of course, as you mentioned, you alluded to the fact there's lots of new imaging modalities out there. It was very illuminating and just an excellent resource for the options that exist and when they're useful. You did a great job summarizing it. And I encourage our readers to check out your article, to refresh themselves, update themselves on what's happened in this space. And of course, we can't summarize them all today, but I was wondering if you could possibly walk us through a hypothetical case of a patient who comes in with a history very suspicious for SIH? How would you approach this patient? Say you have gotten imaging that suggested that there is a spinal fluid leak and now you have to figure out where it is. Dr Madhavan:  Yeah. So, you know, I think the most typical scenario it'll be a patient who has been seen by one of my excellent neurology colleagues and they've done a brain MRI and they've made the diagnosis through a combination of clinical information and brain MRI finding. And then the next thing we'll do always is, we'll obtain a spine MRI. So, I think of the purpose of the spine MRI as to determine what type of spinal fluid leak they have. On the spine MRI, if you see extradural CSF, those patients essentially always will have a dural tear. And it may be a ventral dural tear or a lateral dural tear. But if you see extradural CSF, that is pretty much what they have. And conversely, if you don't see extradural CSF---if you just see, for example, many meningeal diverticula, but you don't see anything else particularly abnormal---most of those patients have a CSF venous fistula, just common things being common. So I use the spine MRI to determine what type of leak they have. And then the next thing I think about is, okay, I'm going to do a myelogram on this patient. How do I want to position them? Because it turns out that positioning is probably the most important factor for finding these spinal fluid leaks. You have to have the patient positioned correctly to find the leak that you're trying to localize. And so, if I suspect they have a ventral dural tear, I will always position those patients prone for their myelogram. And I might do one of many different types of myelograms. And, you know, the article talks about things like digital subtraction myelography and dynamic CT myelography. And you can find any of these leaks with any of those techniques, but you just have to have the patient positioned correctly. So, if I think I have a ventral dural tear, I'll put them prone for the myelogram. If I think they have a lateral dural tear, I'll put them in the cubitus position for the myelogram. And also, if they- if I think they have a CSF-venous fistula, I'll also put them in the decubitus position. Obviously if you're putting them in the decubitus position, you have to decide whether it's going to be left or right side down. So that may require a two-day exam. Sometimes you don't have to; in many cases, we're able to just do everything in one day. But those are all the different factors I think about when I'm trying to determine how I'm going to work those patients up further. So, I really use the spine MRI chiefly to think about what type of leak they're going to have and how I'm going to plan the myelogram. Dr Grouse:  That's really great. And it's, I think, really nice to emphasize how much the positioning matters in all this, which I think is not something we've been classically taught as far as the diagnosis of spinal leaks. Another thing I'm really interested in your opinion on is, you talked a lot about how to optimize and what can make you successful at diagnosis. I'm curious what you think one of the easiest mistakes to make or, you know, that we should hopefully avoid when treating patients with this disease. Dr Madhavan:  Yeah. And I think, you know, one other thing that's been discussed a lot in this topic… you know, we've talked about the patients with a normal brain MRI. Another barrier or challenge particularly with CSF-venous fistulas is, sometimes they can be very subtle on imaging. So, it's not always you see it very definitive CSF-venous fistula where you can say, like, there's no question, that's a fistula. There are many times where we do a good-quality myelogram and we see something that looks, like, possible for a CSF venous fistula, or probable. If I had to put a number on it, maybe there's a 50 to 70% chance of real. So, in those cases, we end up wondering, like, should we treat this suspected leak? And I think one common mistake  or one thing that needs to be looked at further is, how do we handle these patients where we don't know whether the fistula is real or not? That's usually something where I will have a discussion with the patient, and I'm usually just very upfront with him about my interpretation of the imaging. I'll just tell them, we did a good-quality myelogram. You did a great job. We got good images. I don't see anything definitive, but I see this thing that I think has maybe a 60% chance of being real. And then I'll confer with one of my neurology colleagues and we'll decide whether it's worth treating that or not. And we'll just be very upfront with a patient about whether- about the likelihood of its success and what their long-term prognosis is. And oftentimes we let them make the decision. But I think that remains to be one of the big challenges is, how do we treat these patients who have suspected leaks that are not definitive on imaging. Dr Grouse:  That sounds absolutely like an important area where there can be problems, so I appreciate that insight. I'm interested what you think in your article would come as the biggest surprise to our listeners who may not have kept up as much with all of the changes that have happened in recent years? Dr Madhavan:  One of the things that was certainly, at least, a surprise to me as I was going through my training and learning about this topic is how diverse myelography has really become. You know, when I was a radiology resident, I learned about myelography as this thing that we've been doing for 30 to 40 years. And historically we've used myelograms just to look for degenerative changes: disc bulges, you know, disc herniations and things like that. Now that MRI is more prevalent, we don't use it as much, but it has turned out that it has a very big role in patients with spinal fluid leaks. Furthermore, something that I've learned is just how diverse these different types of myelograms have become. It used to kind of be just that a myelogram is a myelogram is a myelogram, but now we have different types of positioning, different types of equipment that we use. We vary the timing between contrast injection and imaging to optimize success for finding spinal fluid leaks. So, I think many times I talk to people who may not be as familiar with this field and they're surprised at just how diverse that has become and how sophisticated some of the various myelographic techniques have become and how much that really makes a difference in being able to accurately diagnose these patients. Dr Grouse:  Well, I can say it was a surprise to me. Even as someone who does treat quite a few patients with this condition, I was surprised to see the breadth of different options that have become available. And then kind of a follow-up to that, what do you think the current area of controversy is in this area of diagnosis and treatment? Dr Madhavan:  The biggest ones are ones you've sort of already alluded to. So, one big one is, how far do we go in patients who have a normal brain MRI who still have a clinical suspicion of the disease? And sometimes it's really hard, because sometimes you will find patients who clinically have a very strong case for having spontaneous intracranial hypotension. You look at them, they have very acute-onset orthostatic headaches. There's no better explanation for their symptoms that we know of. And it's hard to know what to do with those patients, because some of them want to continue to undergo diagnostic workup, but you can only do so many myelograms and you can only do so much with this diagnostic workup that requires some radiation dose before it becomes very challenging. That's a major point of just, I guess, ongoing research as to what can we do better for that subset of patients. Fortunately, it's not all of them, it's a subset of them, but I think we could help those patients better in the future as we learn more about the disease. So that's one. And the other one is treating these equivocal findings, like I discussed.  And where should our threshold be to treat a patient, and what type of treatment should we do in patients where we don't know whether a leak is real? Should we just do a very noninvasive- relatively noninvasive blood patch? Do we do an embolization where we're leaving a foreign body there? Is it worth sending those patients to surgery? Those are all unanswered questions and things that continue to spark ongoing debate. Dr Grouse:  Do you think that there's going to be any new big breakthroughs, or even, do you know of any big developments on the horizon that we should be keeping our eyes out for? Dr Madhavan:  You know, I think for me the biggest thing is, imaging is dramatically improving. We talked a little bit about photon counting detector CT in our article, and that's one of the newest and best techniques for imaging these patients because it has very, very high resolution, it has a lower radiation dose, it has allowed us to find leaks that we were not able to find before. And there are other high-resolution modalities that are emerging and becoming more accessible to things like cone beam CT which we do in addition to digital subtraction myelography. And on top of that, we've started to use AI-based tools to make images look a lot better. So, there are various AI algorithms that have come out that allow us to remove artifacts from imaging. They help us image patients with a bigger body habitus better without running into a lot of imaging artifacts. They help us reduce noise in imaging. They can just give us better-quality images and aid us in the diagnosis. For me as a radiologist, those are some of the most exciting things. We're finding less invasive ways with less radiation to better diagnose these patients with just better-quality imaging. Dr Grouse:  Well, that is definitely something to be excited about. So, I just want to thank you so much for talking with us today. It's been such an interesting, informative discussion and a real privilege to talk with you about this important topic. Dr Madhavan:  Yeah, thanks so much. I really appreciate the time to talk with you, and I look forward to seeing the article out there and hopefully getting some interesting questions. Dr Grouse:  Again, today I've been interviewing Dr Ajay Madhavan about his article on Radiographic Evaluation of Spontaneous Intracranial Hypotension, which he wrote with Dr Levi Chasen. This article appears in the most recent issue of Continuum on disorders of CSF dynamics. Be sure to check out Continuum Audio episodes from this and other issues, and thank you to our listeners for joining today. Dr Monteith: This is Dr Teshamae Monteith, Associate Editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use the link in the episode notes to learn more and subscribe. AAN members, you can get CME for listening to this interview by completing the evaluation at continpub.com/audioCME. Thank you for listening to Continuum Audio.

GLP-1 receptor agonists have changed the landscape of obesity treatment, offering levels of weight loss once thought unattainable without surgery. But what happens after the weight is lost? And can we really talk about success without talking about maintenance? While much of the public discourse fixates on dramatic weight loss numbers, the harder question is what comes next. Can lifestyle interventions alone sustain weight loss after GLP-1 cessation? How do metabolic adaptations and behavioral relapse factor in? And what does the data actually show about relapse rates, nutritional adequacy, and lean mass preservation when using these medications? In this episode, Danny sits down with Tara Schmidt, dietitian at the Mayo Clinic, to examine the intersection of pharmacology and behavior in long-term weight management. Tara Schmidt is a registered dietitian and an instructor of nutrition at Mayo Clinic. As the lead dietitian for the Mayo Clinic Diet, she provides guidance rooted in evidence-based principles. She hosts the Mayo Clinic On Nutrition podcast and co-authored The Mayo Clinic Diet: Weight Loss Medications Edition. Timestamps [05:17] Understanding weight loss maintenance [08:44] Defining success in weight loss maintenance [11:54] Predictors of maintenance: self-monitoring and behavioral strategies [23:37] Pharmacological interventions: GLP-1 receptor agonists [31:06] Dietary considerations for those taking GLP-1 RAs [37:07] Addressing misconceptions about weight loss drugs [42:48] Final thoughts and takeaways [48:49] Key ideas (Premium-only) Links/Resources Subscribe to Sigma Nutrition Premium Go to episode page Join the Sigma email newsletter for free Enroll in the next cohort of our Applied Nutrition Literacy course Visit sigmanutrition.com

Host: Darryl S. Chutka, M.D. Guests: Mary Lang; Caroline M. Gearin; Nick R. Winder, SPT Students in the various fields of medicine deal with a variety of stresses. Perhaps one of the biggest stresses is getting accepted into their respective school to begin their training. Once enrolled, they're then provided a large amount of information to be memorized and essentially need to learn a new language. They have pressure to do well on exams and spend countless hours in study or on the wards. Many students deal with financial stresses, often graduating with a tremendous student loan debt. So, what's life like as a student? How do students deal with these stresses?  What's the application procedure like and are there ways to increase the chances of getting accepted? Do our schools devote enough time to our students' wellness and burn-out prevention? These are some of the questions we'll cover in this podcast as we discuss “Life as a Student”. My three guests are all students in a variety of medical training programs. Mary Lang is a 2nd year medical student at the Mayo Alix School of Medicine after obtaining a degree in biomedical engineering. Caroline Gearin is a 2nd year physician assistant student at the Mayo Clinic School of Health Sciences and also has a bachelor's degree in health science. Nick Winder is a 2nd year physical therapy student at the Mayo Clinic physical therapy doctoral program. Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts 

Fast food, processed foods, Roundup, for-profit hospitals and insurance, and drug companies shifting from cures to chronic treatments are major issues plaguing our healthcare system. Despite spending more than the next ten countries combined, America has the worst health outcomes. Join me as I chat with Dr. Jim Roach, an expert in integrative medicine known for his work on cancer strategies. A published researcher, speaker, and best-selling author, Jim has spoken at major venues like the Mayo Clinic and has been featured over 100 times in national and international media. Jim specializes in holistic medicine and is double-boarded in integrative medicine. Jack Canfield called him one of the most encyclopedic minds he's met. Our conversation covered topics like the "sick-care" system, big pharma's influence on medical education, natural alternatives for chronic diseases, and the healing power of a peaceful mind.Suggested Resources:The Midway CenterRed Yeast Rice for HypercholesterolemiaThe Synergistic Interplay between Vitamins D and K for Bone and Cardiovascular HealthCurcumin: A Review of Its Effects on Human HealthSend me a text! This episode is proudly sponsored by: SizzlefishLet's talk about fueling your body with the best nature has to offer. If you're looking for premium, sustainable seafood delivered straight to your door, you need to check out Sizzlefish! Head to sizzlefish.com and use my code “wellnstrong” at checkout for an exclusive discount on your first order. Trust me, you're going to taste the difference with Sizzlefish! If you're looking for that healthy, radiant, post-vacation glow, you need to checkout OSEA! And right now, you can get 10% off your first order at OSEAMalibu.com with the code WELLNSTRONG!Join the WellnStrong mailing list for exclusive content here!Want more of The How To Be WellnStrong Podcast? Subscribe to the YouTube channel. Follow Jacqueline: Instagram Pinterest TikTok Youtube To access notes from the show & full transcripts, head over to WellnStrong's Podcast Page

In this special episode, Dr. Shaji Kumar from the Mayo Clinic speaks with Blood editor Dr. Laurie Sehn on a paper recently published in Blood, "Eliminating the Need for Sequential Confirmation of Response in Multiple Myeloma". The findings demonstrate eliminating the need for sequential confirmation of response in multiple myeloma. The study, involving 583 episodes of progression, found that simultaneous confirmation of disease progression using two different markers (e.g., serum protein electrophoresis and serum free light chain assay) was 98% accurate, compared to 82% for sequential confirmation. This suggests that simultaneous confirmation could improve clinical trial accuracy and reduce false censoring. The International Myeloma Working Group is set to revise its response criteria to incorporate these findings, potentially simplifying disease assessment and reducing the need for multiple blood draws.

Chronic Total Occlusion in 2025   Guest: Gregory Barsness, M.D. Host: Malcolm Bell, M.D.   Chronic (>3 months) complete epicardial coronary obstructive lesions, often referred to as CTOs, are recognized in a large minority of those referred for coronary angiography yet historically represent

What really happens when a keynote speaker doesn't get the gig? In this episode, Jan pulls back the curtain on the wild, weird, and sometimes downright baffling feedback she's received after not being chosen for events. From strange selection methods to unexpected competition, you'll hear behind-the-scenes stories that are equal parts hilarious and head-scratching. If you've ever wondered what goes on in the speaker selection process—or just want a good laugh—you don't want to miss this one.   https://www.TheWorkLady.com  Jan McInnis is a top change management keynote speaker and comedian. She uses short funny stories to emphasize her tips on how businesses can use humor to handle change. Jan is a top conference keynote speaker, comedian, Master of Ceremonies, and comedy writer. She has written for Jay Leno's The Tonight Show monologues as well as many other people, places, and groups—radio, TV, syndicated cartoon strips, guests on The Jerry Springer Show (her parents are proud). For over 25 years, she's traveled the country as a keynote speaker and comedian, sharing her unique and practical tips on how to use humor in business (yes, it's a business skill!). She's been featured in The Huffington Post, The Wall Street Journal, and The Washington Post for her clean humor, and she's the author of two books: Finding the Funny Fast – How to Create Quick Humor to Connect with Clients, Coworkers, and Crowds, and Convention Comedian: Stories and Wisdom From Two Decades of Chicken Dinners and Comedy Clubs. She also has a popular podcast titled Comedian Stories: Tales From the Road in Under 5 Minutes. In her former life, she was a marketing executive in Washington, D.C. for national non-profits, and she received the Greater Washington Society of Association Executives “Excellence in Education” Award. Jan's been featured at thousands of events from the Federal Reserve Banks to the Mayo Clinic.   https://www.TheWorkLady.com https://youtu.be/BtjxzDn-QLE https://www.linkedin.com/in/janmcinnis https://twitter.com/janmcinnis https://www.pinterest.com/janmcinnis/pins/ https://www.youtube.com/c/JanMcInnisComedian https://www.facebook.com/ComedianJanMcInnis https://www.instagram.com/jan.mcinnis/   Jan has shared her humor keynotes from Fortune 500 companies to international associations. Groups such as . .. Healthcare. . . Mayo Clinic, Health Information Management Associations, Healthcare Financial Management Associations, Hospitals, Abbott Pharmaceuticals, Sanofi Aventis Pharmaceuticals, Kaiser-Permanente, Davita Dialysis Centers, Blue Cross, Blue Shield, Home Healthcare Associations, Assisted Living Associations, Healthcare Associations, National Council for Prescription Drug Companies, Organization of Nurse Leaders, Medical Group Management Associations, Healthcare Risk Associations, Healthcare Quality Associations   Financial. . . Federal Reserve Banks, BDO Accounting, Transamerica Insurance & Investment Group, Merrill Lynch, treasury management associations, bankers associations, credit unions, Money Transmitter Regulators Association, Finance Officers Associations, automated clearing house associations, American Institute of CPAs, financial planning companies, Securities, Insurance, Licensing Association   Government . . . purchasing officers associations, city clerks, International Institute of Municipal Clerks, National League of Cities, International Worker's Compensation Fund, correctional associations, LA County Management Association, Social Security Administration, Southern California Public Power Authority, public utilities, U.S. Air Force, public personnel associations, public procurement associations, risk management associations, Rehabilitation associations, rural housing associations, community action associations   Women's Events. . . American Heart Associations, Go Red For Women luncheons, Speaking of Women's Health, International Association of Administrative Professionals, administrative professionals events, Toyota Women's Conference, Women in Insurance and Financial Services, Soroptimists, Women in Film & Video, ladies night out events, Henry Ford Health Centers Women's Event, spirit of women events, breast cancer awareness,   Education . . . School Business Officials associations, school superintendent associations, school boards associations, state education associations, community college associations, school administrators associations, school plant managers associations, Head Start associations, Texas adult protective services, school nutrition associations, Association of Elementary and Middle School Principals, principal associations, library associations   Emergency, safety, and Disaster . . . International Association of Emergency Managers, Disney Emergency Managers, state emergency management associations, insurance groups, COPIC, Salt Lake County Public Works and Municipal Services Disaster Recovery Conference, Pennsylvania Governor's Occupational Safety and Health conference, Mid Atlantic Safety conference and Chesapeake Regional Safety Council, Risk associations.  

With Kevin Damman, University Medical Center Groningen, Groningen - The Netherlands, Floran Sahiti, University Hospital of Wurzburg, Wurzburg - Germany, Joao Pedro Ferreira, University of Porto, Porto - Portugal, Novi Yanti Sari, Siloam Hospitals Group, Jakarta - Indonesia, Marat Fudim, Duke University Medical Center, Durham, NC - USA, Gregorio Tersalvi, Mayo Clinic, Rochester, MN - USA, Jose Luis Morales Rull, University Hospital Arnau de Vilanova, Lleida - Spain and Cornelia Margineanu, Bucharest - Romania. In this episode, we discuss four late-breaking clinical trials presented at the Heart Failure Congress 2025 in Belgrade, Serbia. First, Kevin Damman presents the results of FUTURE-HF, a first-in-human study evaluating the long-term safety, accuracy, and clinical utility of a novel implantable IVC sensor for remote heart failure management. Next, Joao Pedro Ferreira highlights the key findings of SOGALDI-PEF, a crossover trial comparing SGLT2 inhibitor monotherapy versus combination therapy with an SGLT2 inhibitor and a mineralocorticoid receptor antagonist (MRA) in reducing NT-proBNP levels. Third, Marat Fudim reports on the MUSIC-HFpEF phase 1/2a trial, which explores the safety and preliminary efficacy of a novel gene therapy using adeno-associated virus vectors in patients with HFpEF. Finally, Jose Luis Morales Rull shares insights from PREFER-HF, a study assessing the effects of intravenous or oral iron therapy versus placebo in patients with HFpEF and iron deficiency anemia. FUTURE-HF: Long-term safety, accuracy, and utility of a novel implantable IVC sensor for remote HF management - Kevin Damman, University Medical Center Groningen, Groningen, The Netherlands. Host: Floran Sahiti, University Hospital of Wurzburg, Wurzburg, Germany doi: 10.1016/j.jchf.2025.01.019. SOGALDI-PEF: SOdium-Glucose cotransporter 2 inhibitor with and without an ALDosterone AntagonIst for heart failure with preserved ejection fraction – Joao Pedro Ferreira, University of Porto, Porto, Portugal. Host: Novi Yanti Sari, Siloam Hospitals Group, Jakarta (Indonesia).  MUSIC-HFpEF: Gene therapy in Heart Failure with Preserved Ejection Fraction – Marat Fudim, Duke University Medical Center, Durham, NC, USA. Host: Gregorio Tersalvi, Mayo Clinic, Rochester, MN, USA PREFER¬-HF: Effects intravenous iron or oral iron therapy compared to placebo in HFpEF with iron deficiency anemia - Jose Luis Morales Rull, University Hospital Arnau de Vilanova, Lleida, Spain. Host: Cornelia Margineanu, Bucharest, Romania. This 2025 HFA Cardio Talk podcast series is supported by Bayer AG in the form of an unrestricted financial support. The discussion has not been influenced in any way by its sponsor.

If your doctor is recommending that you get a mastectomy, you will likely have some choices about how the surgery is performed. Your breast cancer treatment, your body, your breast shape and your lifestyle affect not only your options, but also the pros and cons of your options. There's no one method that works best for everyone because each person is unique. Today we are going to be exploring one specific type of mastectomy – the nipple-sparing mastectomy. This is a skin-sparing mastectomy that leaves the nipple and areola intact and usually improves the overall look of the reconstructed breast. Joining us on the show today are two very special guests: Dr. Mara Piltin, a Breast and Melanoma Surgical Oncologist and Physician Assistant, Maddie Beiswanger, both from Mayo Clinic. They are going to tell us more about nipple-sparing mastectomy procedures, current research that is being conducted around the use of minimally invasive robotic surgery to assist in these procedures and the possible benefits that these innovations can provide. This episode of The Real Pink Podcast is brought to you by Intuitive Surgical. Intuitive is a global technology leader in minimally invasive care and the pioneer of robotic-assisted surgery. Intuitive has been advancing minimally invasive care since 1995 with the goal of helping physicians improve the lives of people around the world. You can learn more at www.Intuitive.com

Une étude publiée en mai 2025 dans la revue JAMA Network Open, menée par le Barrow Neurological Institute et la Mayo Clinic, a révélé une association significative entre la proximité des terrains de golf et un risque accru de développer la maladie de Parkinson.Méthodologie de l'étudeLes chercheurs ont analysé les données de 419 patients atteints de la maladie de Parkinson et de 5 113 témoins appariés, issus du Rochester Epidemiology Project, couvrant une période de 1991 à 2015. Ils ont examiné la distance entre le domicile des participants et les terrains de golf, ainsi que la nature de leur approvisionnement en eau potable.Résultats principauxLes personnes résidant à moins d'un mile (environ 1,6 km) d'un terrain de golf présentaient un risque accru de 126 % de développer la maladie de Parkinson par rapport à celles vivant à plus de six miles.Le risque diminuait progressivement avec l'éloignement du terrain de golf, suggérant une relation dose-réponse.Les individus vivant dans des zones desservies par des systèmes d'eau potable alimentés par des nappes phréatiques situées sous des terrains de golf avaient un risque presque doublé de développer la maladie, comparé à ceux vivant dans des zones sans terrain de golf.Hypothèses explicativesLes terrains de golf sont souvent entretenus avec des quantités importantes de pesticides pour maintenir la qualité des pelouses. Aux États-Unis, l'utilisation de pesticides sur les terrains de golf peut être jusqu'à 15 fois supérieure à celle observée en Europe. Ces substances chimiques peuvent s'infiltrer dans les nappes phréatiques, contaminant ainsi l'eau potable des zones avoisinantes.De plus, certaines zones géologiques, comme celles avec des sols perméables ou des formations karstiques, facilitent la migration des pesticides vers les sources d'eau souterraines.Limites de l'étudeBien que l'étude établisse une association entre la proximité des terrains de golf et un risque accru de maladie de Parkinson, elle ne prouve pas une relation de cause à effet. Les chercheurs n'ont pas mesuré directement les niveaux de pesticides dans l'eau potable ni pris en compte d'autres facteurs environnementaux ou génétiques pouvant influencer le risque.Cette étude souligne l'importance de considérer les facteurs environnementaux, tels que l'utilisation intensive de pesticides sur les terrains de golf, dans l'évaluation des risques de maladies neurodégénératives comme la maladie de Parkinson. Des recherches supplémentaires sont nécessaires pour confirmer ces résultats et élaborer des recommandations de santé publique appropriées. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

Send us a textLily Johnston, MD, MPH, is board-certified in both vascular and general surgery. Dr. Johnston obtained her undergraduate education at Princeton University in New Jersey and received her Medical Doctorate from the University of California, San Diego; she completed her residency in general surgery at the University of Virginia in Charlottesville and then completed a fellowship in vascular surgery at the Mayo Clinic in Rochester, MN.After several years of practicing vascular surgery full-time, Dr. Johnston witnessed too many people losing their limbs and even their lives to preventable and reversible diseases - this inspired her to found Vascular Health Institute in an effort to forward cardiovascular health and wellness. Dr. Johnston has now dedicated her career to addressing the root cause of cardiovascular disease and is passionate about bringing the principles of functional medicine and metabolic health to her patients.Dr. Johnston's clinic: www.nexushealthspan.comDr. Greg's clinic: www.fitrxwellnessok.com

What do you do when conventional gastric tubes are not an option? In this week's episode of BackTable, host Dr. Ally Baheti speaks with interventional radiologist Dr. Alex Wallace and physician assistant Lisa Rotellini-Colvet from the Mayo Clinic in Arizona about the percutaneous transesophageal gastrostomy (PTEG) procedure. The discussion explores how PTEG offers a transformative solution for patients who are not candidates for traditional transabdominal gastrostomy access. Suitable candidates for PTEG include individuals with malignancies, peritoneal carcinomatosis, prior gastrectomies, or ascites. --- This podcast is supported by: Medtronic Emprinthttps://www.medtronic.com/emprint --- SYNPOSIS Dr. Wallace and Lisa provide valuable insights on the benefits of early patient selection, thorough pre-procedural evaluation, step-by-step procedural guidance, and key considerations for post-procedural care. They also highlight the critical role of patient and staff education in achieving successful outcomes. The episode features real-world experiences, including a powerful story of a patient who benefited from her PTEG for over 560 days. Our guests advocate for increased awareness of PTEG and its early consideration in patients with advanced abdominal cancers, emphasizing its potential to greatly improve quality of life. --- TIMESTAMPS 00:00 - Introduction01:38 - History and Explanation of PTEG08:12 - Pre-Procedure Evaluation11:48 - Procedural Walkthrough20:46 - Post-Procedure Care and Suction Management24:45 - Exchange Process and Troubleshooting30:11 - Patient Education and Staff Training35:54 - Improved Quality of Life for Patients --- RESOURCES Percutaneous Transesophageal Gastrostomy: Procedural Technique and Outcomes (Rotellini-Coltvet, Wallace et al, 2023):https://pubmed.ncbi.nlm.nih.gov/37419279/

Dr. Enniniya Kamalu joins Stranger Fruit Vol VI, Episode 2 for a conversation rooted in resilience, focus, and presence. In this episode, we unpack the meaning of grit—not just as endurance through difficulty, but as a combination of purpose, perseverance, and passion that helps us stay grounded.  Together, we discuss how to harness grit in a healthy way and how to remain connected to the people and purpose that matter most. Timestamps:  0:00 Introduction and Foundations of Grit 6:16 Family Influence and Personal Growth 16:46 Identity and Personal Transformation 25:59 Balancing Ambition and Present Contentment 38:25 Navigating Transitions and Lasting Change Reference: Intro Music: Bosch's Garden – by Kjartan Abel. This work is licensed under the following: CC BY-SA 4.0 Attribution-ShareAlike 4.0 International.

At the Mayo Clinic in Rochester, Minnesota, Nursing Manager Josh Meyer has seen measurable benefits from implementing CensiTrac's AI² functionality. The tool has become an integral part of how the department monitors quality, manages staffing, and improves daily operations.With AI², the team is able to track key quality metrics across sterile processing workflows. From detecting sharp items improperly placed in containers to identifying holes in blue wraps or missing instruments in trays, every detail is logged and analyzed. This granular data helps ensure that only properly prepared and fully compliant instrument sets are sent to the operating room.In addition to quality monitoring, the system provides valuable insights into staffing needs and productivity levels. Meyer and his team use this data to assess daily output and identify where staffing adjustments may be necessary to maintain performance standards.By leveraging the technology, the sterile processing team has strengthened its operational visibility, improved accountability, and enhanced the overall quality of surgical support services.

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, and William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, discuss global trends in diagnostic manufacturing and their implications for laboratory professionals. Topics include: Emerging innovations in mass spectrometry, next-generation sequencing, automation, and artificial intelligence. Fierce competition in the global manufacturing landscape as new companies enter the market. Geopolitical dynamics influencing where innovations are deployed. Why laboratory professionals need to drive innovation implementation to maximize benefits for clinicians and their patients.

Dr Stephen Ansell from Mayo Clinic in Rochester, Minnesota, and Dr Brian Hill from Cleveland Clinic Taussig Cancer Institute in Ohio summarize major treatment advances over the past year and review relevant ongoing clinical trials for patients with non-Hodgkin lymphoma. CME information and select publications here.

Send us a textWhat happens when you trade modern conveniences for a bicycle and a bucket in rural Zambia? For Marcus Frick, a resilience coach and former leader at the Mayo Clinic, his 27-month Peace Corps experience profoundly transformed his understanding of what truly constitutes a problem worth worrying about.Drawing from experiences like biking for hours with a fever to get antibiotics or doing laundry by hand while villagers watched and commented, Marcus developed a perspective that now helps busy professionals recalibrate their relationship with stress. His simple but powerful framework—asking "Is anyone's life in danger?" and "Will we figure this out?"—cuts through the noise of perceived problems that dominate our digital workdays.As a health coach at the Mayo Clinic, Marcus has observed that many people achieve health goals but struggle to maintain them because they rely on unsustainable methods. The solution isn't more willpower but rather establishing a compelling vision (like one client's desire to be "the fun, cool grandma") and implementing habits that work within real-life constraints. This approach aligns with his newsletter 66.1, named for the average age at which Americans develop chronic disease, which explores evidence-based approaches to extending not just lifespan but also healthy years of life.For building confidence, Marcus emphasizes that action precedes feeling—"competence precedes confidence." Rather than trying to feel confident first, start with small, consistent actions that build skill. His own "daily minimum" of 100 push-ups and 100 air squats ensures forward momentum even on the busiest days. By applying the 80/20 principle, which focuses on the few high-leverage activities that yield the most results, professionals can simplify their approach while maximizing their impact.Ready to transform your relationship with stress, energy, and self-belief? Marcus offers one simple invitation: "Just run the experiment. Whatever you're wondering about trying, go try it and learn—don't hold back."Link to 66.1 - https://66point1.beehiiv.com/Have you purchased the copy of Inspire Someone Today, yet - Give it a go geni.us/istbook Available on all podcast platforms, including, Apple Podcasts, YouTube, Spotify

On this episode of DGTL Voices, Dr. Anjali Bhagra shares her inspiring journey from India to becoming a professor of medicine at Mayo Clinic. She discusses her roles in enterprise automation and integrative medicine, emphasizing the need for trust and transparency in healthcare. She reflects on her leadership style, the significance of GRIT, and the ways she recharges. The conversation concludes with her powerful mantra for living a fulfilling life.

In this episode, Laura Dyrda, Editor-in-Chief at Becker's Healthcare, joins Scott Becker to explore key trends in healthcare, including major innovation initiatives from Mayo Clinic and Emory Healthcare, along with a notable rise in CEO turnover and what it means for the industry's future.

In this encore episode, hosts Chris Boyer and Reed Smith explore how evolving financial pressures and care delivery shifts are forcing health systems to rethink their business models. From the rise of value-based care to growing partnerships with retail and digital-first players, this conversation breaks down the key factors shaping the industry's strategic realignment. Topics include: The growing divide between traditional hospital revenue streams and emerging care models. How consumerism and digital health are driving new competitive threats. Why innovation isn't just about tech — it's about new models of care and payment. What this means for marketing, strategy, and long-term viability. Originally aired as TP127, this episode includes an expert interview with Jeffrey Carr, industry leader and operational administrator for the Mayo Clinic. This conversation remains highly relevant in today's environment of disruption, realignment, and strategic reinvention. Mentions from the Show:  Jeff Carr on LinkedIn 4 Hospital Business Models for Consumer-Centric Healthcare Digital Clinic podcast Reed Smith on LinkedIn Chris Boyer on LinkedIn Chris Boyer website Chris Boyer on BlueSky Reed Smith on BlueSky Learn more about your ad choices. Visit megaphone.fm/adchoices

Spontaneous intracranial hypotension reflects a disruption of the normal continuous production, circulation, and reabsorption of CSF. Diagnosis requires the recognition of common and uncommon presentations, careful selection and scrutiny of brain and spine imaging, and, frequently, referral to specialist centers.  In this episode, Gordon Smith, MD, FAAN speaks with Jill C. Rau, MD, PhD, author of the article “Clinical Features and Diagnosis of Spontaneous Intracranial Hypotension” in the Continuum® June 2025 Disorders of CSF Dynamics issue. Dr. Smith is a Continuum® Audio interviewer and a professor and chair of neurology at Kenneth and Dianne Wright Distinguished Chair in Clinical and Translational Research at Virginia Commonwealth University in Richmond, Virginia. Dr. Rau is an assistant professor of clinical neurology at the University of Arizona, School of Medicine-Phoenix in Phoenix, Arizona. Additional Resources Read the article: continuumjournal.com Subscribe to Continuum®: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Host: @gordonsmithMD Full episode transcript available here Interview with Jill Rau, MD Dr Jones: This is Dr Lyell Jones, Editor-in-Chief of Continuum. Thank you for listening to Continuum Audio. Be sure to visit the links in the episode notes for information about earning CME, subscribing to the journal, and exclusive access to interviews not featured on the podcast. Dr Smith: This is Dr Gordon Smith. Today I'm interviewing Dr Jill Rau about her article on clinical features and diagnosis of spontaneous intracranial hypotension, which she wrote with Dr Jeremy Cutsworth-Gregory from the Mayo Clinic. This article appears in the 2025 Continuum issue on disorders of CSF dynamics. I'm really excited to welcome you to the Continuum podcast. Maybe you can start by just telling our listeners a little bit about yourself? Dr Rau: Hi, thanks for having me. I'm really honored to be here, and I really enjoyed writing the paper with Dr Cutsforth-Gregory. I hope you guys enjoy it. I am the director of headache medicine at the Baba Bay Neuroscience Institute at Honor Health in Scottsdale, Arizona. I'm also currently the chair of the special interest group in CSF Dynamics at the American Headache Society, and I've had a special interest in this field since I first watched Dr Linda Gray speak at a conference where she talked about spinal CSF leaks and their different presentations. And they were so different than what I had been taught in residency. They're not just the post-LP headache. They have such a wide variety of presentations and how devastating they can be, and how much impact there is on someone's life when you find it and fix it. And I've been super interested in the field and involved in research since that time. And, yeah. Love it. Dr Smith: Well, thanks for sharing your story. And as I reflected on our conversation ahead of time and have been thinking about this issue… this is a cool topic, and every time I read one of these manuscripts and have the opportunity to speak with one of the authors, I learn a ton, because this was something that wasn't even on the radar when I trained back in the 1800's. So, really looking forward to the conversation. I wonder if you could really briefly just summarize or remind for everyone the normal physiology about CSF dynamics, you know, production, absorption, and so forth? Dr Rau: So, the CSF is the fluid that surrounds the brain and the spinal cord, and it's contained by the dura, which is like a canvas or a sac that covers that whole brain and spinal cord. And within the ventricles of the brain, the choroid plexus produce CSF. It's constantly producing and then being reabsorbed by the arachnoid granulations and pushed into the venous space, the cerebral sinuses, venous sinuses. And also some absorption and push into the lymphatics that we've just learned about in the past year. This is kind of new data coming out, so always learning more and more about CSF, but we know that it bathes the brain and the spinal cord, helps keep some buoyancy of the brain as well as pushing nutrients in and pulling out metabolic waste. And it sort of keeps the brain in the state of homeostasis that's happy. And so, when there's a disruption of that flow and the amount of fluid there, that disrupts that, that can cause lots of different symptoms and problems for people. Dr Smith: One of the many new things I learned is that even the name of this---spontaneous intracranial hypotension---is misleading. And I think this is clinically relevant, as we'll probably get to in a moment, but can you talk a little bit about this? Is this really like a pressure disorder or a volume disorder? Dr Rau: Yeah. It's almost certainly a volume disorder. We do see in some people that they have low pressure, and it's still part of the diagnostic criteria. But it's there because if you have a low pressure, if you measure an opening pressure and it's below six, if you're measuring it in the spine in the right place, then you have indication that there's low volume. But there's over 50% of people's opening pressure who have a spinal CSF leak, have all the symptoms and can be fixed. So, they have normal pressure in 50% of the people. So, it is an inaccurate term, hypotension, but it was originally discovered because of the thought that it was a low-pressure situation. Some of the findings would suggest low pressure, but ultimately, we are pretty sure it's a low-volume condition. Dr Smith: Another new thing that I learned that really blew me away is how bad this can be. I did a podcast with Mark Burish about cluster, and I was reminded many cluster patients are pushed to the point of suicidal ideation or committing suicide by the severity of pain. And this sounds like for many patients it's equally severe. Can you maybe paint a picture for our listeners why this is so clinically important? Dr Rau: A large number of people, even people who are known to have leaks because they've had them before or they've releaked, they have a lot of brain fog and cognitive impairment. They often have severe headaches when they're upright. So, orthostatic headache is probably the number one most common symptom, and those headaches are one of the worst headaches out there. When people stand up, their fluid is not supporting the brain and there's an intense amount of pain. And so, they spend a large portion of their lives horizontal. And there's associated symptoms with that, it's not just headache pain and brain fog. There's neck pain. There's often subsequent disorders that accompany this, like partial orthostatic tachycardia syndrome. We don't know if that's because of deconditioning or an actual sequela of the disease, but it's a frequent comorbidity. We have patients that have extreme dizziness with their symptoms, but many patients are limited to hours, if that, upright per day, combined, total. And so they live their lives, often, just in the dark, lots of photophobia, sensitive to the light, really unable to function. It's also very hard to find and so underrecognized that a lot of patients, especially if they don't have that really clinical symptom of orthostatic headache. So, it's often missed. So, they're just debilitated. You know, treatments don't work because it's not a migraine and it's not a typical headache. It's a mechanical issue as well as a metabolic issue and not found, not a lot helps it. Dr Smith: So, you know, I have always thought about this as really primarily an orthostatic symptom. I wonder if you can talk about the complexity of this; in particular, kind of how this evolves over time, because it's not quite that simple. And maybe in doing so, you can give our listeners some pearls on when they should be thinking about this disorder? Dr Rau: A large portion of people do have headache with spinal CSF leak, in particular, spontaneous intracranial hypertension- hypotension, excuse me. And that's something to be thought about, is that there are spontaneous conditions where people have either rupture of the dural sac, or an erosion of the dural sac, or a development of a connection between the dura and the venous system. And that is taking away or allowing CSF to escape. In these instances that patients have spontaneous, there may be a different presentation than if they have, like, a postdural puncture or a chronic traumatic or iatrogenic leak. And we're not sure of that yet, but we're looking into that. Still, the largest presentation is headache, and orthostatic headache is very dominant in the headache realm. But over time, patients' brains can compensate for that lack of CSF and start overproducing---or at least we think that's probably what's happening. And you may see a reduction in the orthostatic symptoms over time, and you may see an improvement in the radiographic findings. So, there are some interesting papers that have been published that look at these changes over time, and we do see that sometimes within that first three to four months; this is the most common time to see that change. Other patients may worsen. You may actually see someone going from looking sort of normal radiographically to developing more of a SIH-type of picture on the brain. And so it's not predictable which patients have gone from orthostatic to improvement or the other way around, both radiographically and clinically. So, it can be quite difficult to tell. So, for me, if I have a patient that comes to me and they're struggling with headache… if it's orthostatic, very clearly orthostatic: I lay down, I get considerably better or my headache completely goes away. And then when I stand up, it comes on relatively quickly, within an hour. And sometimes it's a worsening-throughout-the-day type of thing, it's lowest in the morning and it worsens throughout the day. These are the times that it's most obvious to think about CSF leak. Especially if that headache onset relatively suddenly, if it onset after a small trauma. Like I've had patients that say, you know, I was doing yoga and I did some twists and I felt kind of a pop. And then I've had this headache that is horrible when I'm upright but is better when I lay down ever since, you know, since that time. That's kind of a very classic presentation of spinal CSF leak or spontaneous intracranial hypotension. Maybe a less common presentation would be someone who comes to you, they've had a persistent headache for a couple years, they kind of remember it started in March of a couple years ago, but they don't know. Maybe it's, you know, it's a little better when they lay down. It may be a little worse when they're up moving around, but so is migraine, and it's a migrainous headache. But they've tried every migraine drug you can think of. Nothing is responding, nothing helps. I'm always looking at patients who are new daily, persistent headaches and patients who aren't responding to meds even if it's not new daily, but they have just barely any response. I will always go back and examine their brain imaging and get full spine to make sure I'm not missing. And you can never be 100% sure, but it's always good to consider those patients to the best of your ability, if that- have that in the back of your mind. Dr Smith: So obviously, goes without saying, this is something people need to have on their radar and think about. And then we'll talk more about diagnostic tools here in a second. But how common is this? If you're a headache doc, you see a lot of patients who have intractable headaches. And how often do you see this in your headache practice? Now you're- this is your thing, so probably a little more than others, but, you know, how common will someone who sees a lot of headache encounter these patients? Dr Rau: If you see a lot of headache, I mean, currently the thought is it's about 5 in 100,000. That was from a study before we were finding CSF venous fistulas. I think a lot of us think it's more common than that, but it's not super common. We don't have good estimates, but I would guess between 5 and 10 for 100,000 persons, not “persons who come to a tertiary headache clinic with intractable headaches”. So, it's hard to gauge how frequent it is, but I would say it's considerably more frequent than we currently think it is. There's still a group of people with orthostatic headaches that we can't find leaks on; that, once you treat other things that can cause or look for other things that can cause orthostatic headaches. So, there may be even still a pathophysiology out there that is still a leak type. Before 2014, we didn't even know about CSF venous fistulas. And now here we are; like, 50% of them are CSF venous fistulas. So, you know, we're still in a huge learning curve right now. Dr Smith: So, I definitely want to talk about the fistulas in a second. But before moving on, one of the things that I found really interesting is the wide spectrum of clinical phenotype. And we obviously don't have a lot of time to get into all of these different ones, but the one that I was hoping you might talk about---and there's a really great case, and you're on bunch of great case, a great case of this---is brain sagging dementia, not a term I've used before. Can you really briefly just tell our listeners about that, because that's a really interesting story and a great case in your article? Dr Rau: Yeah. So, brain sag dementia is a… almost like an extreme version of a spontaneous intracranial hypotension. Where there is clear brain sag in the imaging---so that's helpful---but the patients present kind of like a frontotemporal dementia. And when this was first started to being determined, you could turn the patient into Trendelenburg, and sometimes they would improve. There are some practitioners that have introduced fluid into the thecal sac and had temporary improvement. Patching has improvement, then they leak again, sometimes  not. But the clinical changes with this have been pretty tremendous to be able to identify that that's a real thing. And in some cases, out of Cedars Sinai, you know, who does a lot of the best research in this, they've had lots of cases where they can't find the leak, but there's clear brain sag that fits with our clinical picture of CSF leaks. So, we're on a learning curve. But yeah, this- they really present. They have disinhibition and cognitive impairment that is very similar to frontotemporal dementia. Dr Smith: Well, so let's talk about what causes this. You mentioned CSF venous fistulas. I mean, that was reported now just over a decade ago, it's pretty amazing. That accounts for about half of cases, if I understand correctly. What are the other causes? And then we'll talk more about therapy in a minute, but what causes this? Dr Rau: So, within the realm of spontaneous, you know, we say it's spontaneous. But the spontaneous cases we account for, they can be tears in the dura, which are usually sort of lateral tears in the dura. They can be little places that rubbed a hole, often on an osteophyte from the spine. They can come from these spinal diverticuli. So, I always describe it to my patients like those balls that have mesh and squishy, and you squeeze them in the- through the mesh, there's the extra little bubbling out. If you think of like the dura bubbling, out in some cases, through the framing of the spine, right where the spinal nerve roots come out, they should poke out like wires from the dura. But in many cases they poke out with this extra dura surrounding them, and we call that spinal diverticuli. And if you imagine like the weakening of where you squeeze that, you know, balloon through your fingers, in those locations, that's a very common place to find a CSF leak, and you can imagine that the integrity of the dura there may be less than it would be if it were not being expanded in that direction. And that's often the most common place we see these CSF venous fistulas. So, you can get minor traumas; like I said, it can be spontaneous, like someone just develops a leak one day. It can be rubbed off, and it can be a development of a connection between the dura and the venous system. There are also iatrogenic causes, but we don't consider them spontaneous. But when you're considering your patients for spontaneous cases, you should consider if they've ever had chronic---even long, long time ago---had any spinal implementation, procedures near the spine, spinal injections, LPs in the past, and especially women who've had epidurals in pregnancy. Dr Smith: All right, so we see a patient, positional severe headache, who meets the clinical criteria. Next step, MRI scan? Dr Rau: Yeah. So, the first thing is always to get the brain MRI with and without contrast. Most places will have a SIH or a spinal CSF leak protocol, but you should get contrast because one of the most pathognomonic findings on brain MRI is that smooth diffuse dural enhancement. And that's a really fantastic thing when you find it, because it's kind of a slam dunk. If you find it, then you will see other findings. It almost never exists alone. But if you see that, it's pretty much a spinal CSF leak. But you're also looking for subdural collections, any indication of brain sag. We do have these new algorithms that have come out in the past couple of years that are helpful. They're not exclusionary---you can have negative findings on the brain and still have spinal CSF leak---but the brain MRI is extremely helpful. If it's positive for the findings, it really does help you nudge you in the direction of further investigations and treatments. Dr Smith: And what about those further investigations and treatments, right? So, you see that there's findings consistent with low pressure, and I guess I should say low intracranial CSF volume. Be that as it may, what's the next step after that? Dr Rau: Depends on where you are and what you can do. I almost always will get a full spine MRI: so, C spine, T spine, and L spine separately. Not, you know, we don't want it all in one picture, because we want to get the full view. And you want to get that with at least T2 highly- heavily T2 weighted with fat saturation in at least the sagittal and axial planes. It's really helpful if you can get it in the coronal planes, but we have to have- often have good talks with your radiologist to get the coronal plane. I spoke about the spinal diverticuli earlier, and I want to clarify a little bit of something. The coronal image will show those really nicely. It's interesting, but 44% of people have those. So just having the spinal diverticuli does not indicate that you have a leak. But if you have a lot of those, there may be more likelihood of having leak than if you don't have any of those. So, I will get all of those and I will look at them myself, but I've been looking at them myself for a long time. But a lot of radiologists in community hospitals, especially not- nonneuroradiologists, but even neuroradiologists, this isn't something that's that everybody's been educated about, and we've been learning so much about it so rapidly in the past ten years. It's not easy to do and it's often missed. And if it's not protocoled properly, the fat saturation's not there, it's very hard to see… you can have a leak and not see it. Even the best people, like- it's not always something that's visible. And these CSF venous fistulas that we talked about are never visible on normal MRI imaging. Nonetheless, I will run those because if I can find a leak---and 90% of the ones that are found on MRI imaging are in the thoracic spine. So that's where I spend the most of my time looking. But if you find it, that's another thing to take to your team to say, hey, look, here it is, let's try and do this, or, let's try and do that, or, I've got more evidence. And there are other findings on the spine; not just the leak, but other findings, sometimes, you can see on spine that maybe help you push you towards, yes, this is probably a leak versus not. Dr Smith: So, your article has a lot of great examples and detail about kind of advanced imaging to, like, find the fistula and what not. I guess I'm thinking most of our listeners are probably practicing in a location where they don't have a team that really focuses on that. So, let's say we do the imaging of the spine and you don't find a clear cause. Is the next step to just do a blood patch? Do you send them to someone like you? What's the practical next step? Dr Rau: Yeah, if your- regardless of whether you find a leak or not, if your clinical acumen is such that you think this patient has a leak or I've treated them for everything else and it's not working and I have at least a high enough suspicion that I think the risk of getting a patch is lower than the benefit that if they got a patch and it worked, I do send my patients for non-directed blood patches, because it currently does take a long time to get them to a center that can do CT myelograms or any kind of advanced imaging to look for sort of a CSF venous fistula or to get treated outside of a nondirected patch. You know, sometimes nondirected patches are beneficial for patients, and there's some good papers out there that sort of explain the low risks of doing these if done properly versus the extreme benefit for patients when it works. And, I mean, I can't tell you how many people come in and tell me how their lives are changed because they finally got a blood patch. And sometimes it works. And it's life-changing for those people. You know, they go back to work. They can interact with their kids again. Before, they didn't know what was wrong, just had this headache that started. So it's worth doing if you have a strong clinical suspicion. Dr Smith: Yeah. I mean, that was great. And, you know, to go back to where we began, this is severe. It's something like 60% of patients with this problem have thought about suicide, right? And you take this patient and cure the problem. I feel really empowered having read the article and talked to you today. And so, I'm ready to go out and look for this. Thank you so much for a really engaging conversation. This has been terrific. Dr Rau: Thank you. I appreciate it. I enjoyed being here. Dr Smith: Again, today I've been interviewing Dr Jill Rau about her article on clinical features and diagnosis of spontaneous intracranial hypotension---which I guess I should say hypovolemia after having talked to you---which she wrote with Dr Jeremy Cutsworth-Gregory. This article appears in the most recent issue of Continuum on disorders of CSF dynamics. Please be sure to check out Continuum Audio episodes from this really interesting issue and other interesting issues. And thank you, our listeners, again for listening to us today. Dr Monteith: This is Dr Teshamae Monteith, Associate Editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use the link in the episode notes to learn more and subscribe. AAN members, you can get CME for listening to this interview by completing the evaluation at continpub.com/audioCME. Thank you for listening to Continuum Audio.

Rafael Fonseca is a distinguished Haematologist at Mayo Clinic, specialising in multiple myeloma and related plasma cell disorders. He earned his medical degree at Universidad Anáhuac in Mexico, and went on to complete his residency in Internal Medicine at the University of Miami, Florida, USA followed by a Hematology and Oncology fellowship at Mayo Clinic in Rochester, Minnesota, USA.     Timestamps  01:44 – Quickfire questions  07:25 – CAR-T cell therapy  10:48 – Anti-CD38 antibodies  13:31 – Minimal residual disease  14:30 – Bispecific antibodies  15:31 – Antibody-drug conjugates  19:04 – ASCO 2025  21:24 – Genetic discoveries  26:28 – Fonseca's three wishes 

Host: Darryl S. Chutka, M.D. Guest: Robert L. Scott, M.D., Ph.D. Pulmonary hypertension is an important medical condition and often underrecognized in primary care. It has a variety of causes, and its most common presenting symptom is dyspnea. As primary care clinicians, we often see patients with symptoms of dyspnea and pulmonary hypertension is not a health problem we commonly encounter. Yet, early recognition and diagnosis is important and has major implications for patient outcomes. What are some clues that a patient might have pulmonary hypertension? What are its most common causes and what are the potential complications if it goes unrecognized? These are some of the questions I'll be asking my guest, Robert L. Scott, M.D., Ph.D., from the Department of Cardiovascular Medicine at the Arizona campus of the Mayo Clinic as we discuss “Pulmonary Hypertension”. ** Course link-- https://ce.mayo.edu/pulmonary-medicine/content/mayo-clinic-pulmonary-hypertension-symposium-2025 **Seats are limited, so visit our website to register now!  Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts 

Think menopause is why you're gaining weight? It's not. The truth: your metabolism stays stable from age 20 to 60. What does change? Your energy balance—and most women don't see it happening. In this episode, I unpack the real reason weight loss feels harder now, and what you can do to shift it. You'll learn how energy in (food) vs. energy out (movement) drives fat loss, why tracking intake matters more than ever, and how your body subtly burns less as you lose weight—without you even noticing. What you'll walk away with: Why “calories” are just energy—and why mindset around them matters The law of thermodynamics: no one gets around it How untracked changes in daily movement stall fat loss Why tracking isn't about judgment—it's data to guide your goals What's really behind midlife weight gain (and it's not your hormones) Cut through the confusion. If weight loss has felt impossible lately, this might be the missing piece.   Get Weekly Health Tips:  thrivehealthcoachllc.com Let's Connect:@‌ashleythrivehealthcoach or via email: ashley@thrivehealthcoachingllc.com Podcast Produced by Virtually You! Sources: Hall, K. D., Heymsfield, S. B., Kemnitz, J. W., Klein, S., Schoeller, D. A., & Speakman, J. R. (2012). Energy balance and its components: Implications for body weight regulation. The American Journal of Clinical Nutrition, 95(4), 989–994. https://doi.org/10.3945/ajcn.112.036350 Thomas, J. G., Bond, D. S., Raynor, H. A., Papandonatos, G. D., & Wing, R. R. (2017). Comparison of smartphone-based behavioral obesity treatment with gold standard group treatment and control: A randomized trial. Obesity, 25(6), 964–972. Chronic intestinal electrical stimulation improves glucose intolerance and insulin resistance in diet‐induced obesity rats Ducrot, P., Méjean, C., Aroumougame, V., Ibanez, G., Allès, B., Kesse-Guyot, E., ... & Péneau, S. (2017). Meal planning is associated with food variety, diet quality and body weight status in a large sample of French adults. The International Journal of Behavioral Nutrition and Physical Activity, 14(1), 12. Meal planning is associated with food variety, diet quality and body weight status in a large sample of French adults - International Journal of Behavioral Nutrition and Physical Activity Catenacci, V. A., Ogden, L. G., Stuht, J., Phelan, S., Wing, R. R., Hill, J. O., & Wyatt, H. R. (2008). Physical activity patterns in the National Weight Control Registry. Obesity, 16(1), 153–161. Relationship Between Body Mass Index and Gray Matter Volume in 1,428 Healthy Individuals Butryn, M. L., Phelan, S., Hill, J. O., & Wing, R. R. (2007). Consistent self-monitoring of weight: A key component of successful weight loss maintenance. Obesity, 15(12), 3091–3096. Consistent Self‐monitoring of Weight: A Key Component of Successful Weight Loss Maintenance Wing, R. R., & Phelan, S. (2005). Long-term weight loss maintenance. The American Journal of Clinical Nutrition, 82(1), 222S–225S. https://doi.org/10.1093/ajcn/82.1.222S Wing, R. R., Papandonatos, G. D., Fava, J. L., Gorin, A. A., Phelan, S., McCaffery, J., & Tate, D. F. (2008). Maintaining large weight losses: The role of behavioral and psychological factors. Journal of Consulting and Clinical Psychology, 76(6), 1015–1021. APA PsycNet Mayo Clinic. (2021). Menopause weight gain: Stop the middle age spread. Mayo Clinic. The reality of menopause weight gain Jefferson Health. (n.d.). The truth about menopause: Debunking 6 common misconceptions. Jefferson Health. The Truth About Menopause: Debunking 6 Common Misconceptions | Jefferson Health American Heart Association. (n.d.). Food diary – How to keep track of what you eat. AHA Healthy Eating. Food Diary — Keep Track of What You Eat and Drink National Weight Control Registry. (n.d.). NWCR Facts. https://www.nwcr.ws McGrath, E. (2025, May 29). Using this 'inclusion strategy' can help you lose weight — and means you get to eat dessert. New York Post. Using this 'inclusion strategy' can help you lose weight — and...

Have you ever woken up from a long night of sleep and still felt tired?According to the Mayo Clinic, the recommended amount of sleep for a healthy adult is at least seven hours a night. But even getting enough sleep isn't enough to be fully rested.As parents, we can quickly become overburdened, overwhelmed, exhausted, discouraged, and restless.Let's take Jesus up on his invitation in Matthew 11:28-30:“Come to me, all you who are weary and burdened, and I will give you rest. Take my yoke upon you and learn from me, for I am gentle and humble in heart, and you will find rest for your souls. For my yoke is easy and my burden is light.”Practice resting in Him. And teach your son to do the same!For more encouragement and parenting advice, visit Trail Life USA or RaisingGodlyBoys.com.

Supplements for Cardiovascular Prevention   Guest: Lisa M. Gilman, APRN, C.N.P. Host: Stephen L. Kopecky, M.D.   Supplement use is a growing industry in which patients seek additional potential benefit of reducing disease burden and improving overall health.  This presentation will be an overview of supplements used to address cardiovascular disease prevention   Topics Discussed: Our patients will often inquire if there are any supplements that would help their heart health. How do you approach this topic? What supplements have been suggested to help improve cardiovascular health? Patients may ask, how do we know if we are purchasing a good supplement? Are there any other considerations to be thinking of to instruct our patients about supplements?   Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode. Podcast episode transcript found here.

We've been led to believe that if only we could focus more, then we could be more productive and more successful. But what if, instead, we could unlock our productivity, intuition, and creativity by utilizing our unfocused mind? That's exactly what you're going to learn on today's show. On this episode of The Model Health Show, our guest is Harvard-trained psychiatrist and brain researcher, Dr. Srini Pillay. Dr. Pillay joins this episode to share mind-blowing insights from his book, Tinker Dabble Doodle Try. You're going to learn specific strategies you can use to harness the power of the unfocused mind to fuel your brain and unlock your potential. Dr. Pillay's message on training and understanding our brains is incredibly powerful. This conversation is going to reframe the way you think about focus and productivity, how you view yourself, and so much more. I hope you enjoy this interview with Dr. Srini Pillay!   In this episode you'll discover:  The two competing circuits in the brain. (11:45) Why allowing your brain to be unfocused is critical. (14:15) What unfocusing is and how it can help you connect with who you are. (14:25) Why having the ability to unfocus is important in the age of AI. (15:41) The role of playfulness and fantasy for longevity. (16:55) How focus can affect your ability to display compassion. (18:21) What mirror neurons are and how they work. (23:38) The health consequences of emotional suppression. (24:14) Why relationships are the key to our emotional health. (26:03) How to use unfocusing to decrease amygdala activation. (27:55) What CIRCA is and how to use it to decrease anxiety. (29:55) Why practicing mindfulness can protect your telomeres. (31:26) How to give your brain a reality check. (33:04) What contrast avoidance theory is. (39:10) Why we have an epidemic of a loss of vitality. (41:32) How to use the reverie technique. (47:32) A question we should ask ourselves about our ideas. (54:41) How unfocusing can help you refine your intuition. (1:01:12) The difference between reverie and mind wandering. (1:04:40) What a tinker table is. (1:22:05)  Items mentioned in this episode include:  Beekeepersnaturals.com/model - Save up to 30% on natural remedies! Organifi.com/Model  - Use the coupon code MODEL for 20% off + free shipping! Tinker Dabble Doodle Try by Dr. Srini Pillay - Get your copy today & unlock your unfocused mind! Life Unlocked by Dr. Srini Pillay - Read Dr. Pillay's first book on overcoming fear! Themodelhealthshow.com/reulay - For Model Health Show listeners: Use this link to get a discounted rate on the Reulay app. Reulay uses short, evidence-based videos to shift your mental state — helping you relax, refocus, and build resilience. It's backed by research from places like the Mayo Clinic and trusted by Fortune 500 teams. Solutions@neurobusinessgroup.com - Email proof of purchase to claim your downloads! Connect with Dr. Srini Pillay Website / Instagram / LinkedIn   Be sure you are subscribed to this podcast to automatically receive your episodes:   Apple Podcasts Spotify Soundcloud Pandora YouTube   This episode of The Model Health Show is brought to you by Beekeeper's Naturals and Organifi. Reinvent your medicine cabinet for with clean, effective products powered by the beehive & backed by science. Claim up to a 30% discount at beekeepersnaturals.com/model. Organifi makes nutrition easy and delicious for everyone. Take 20% off your order with the code MODEL at organifi.com/model.

Today we have Dr. Michael A. Schmidt, the founder, CEO, and Chief Scientific Officer of Sovaris Aerospace, a company focused on assessments and solutions applied to humans in space and extreme environments on Earth.  Michael is also a professor of aerospace medicine at the University of Central Florida College of Medicine, one of the few programs in the U.S. that offers a medical residency in aerospace medicine. Michael is known for his work pioneering the field of precision medicine. He uses molecular analytics, coupled with physiologic and behavioral assessments, to facilitate human performance and resilience on Earth as well as in the extreme environment of space. His work covers a spectrum from NASA, the NFL, the NBA, U.S. Olympic teams, Nike, SpaceX, Axiom Space, NASCAR, Special Operations, the Naval Submarine Medical Research Lab, the Mayo Clinic, and others. We had a long and fascinating conversation with Michael and decided to break the interview into two parts. This episode focuses on Michael's background and the cognitive and physical challenges astronauts experience in spaceflight. We also dive into the many ways that precision medicine is facilitating human performance and resilience here on Earth. In part two of our conversation, Michael talks about his work with NASA and SpaceX on the challenges of civilian spaceflight and the future of Mars exploration, including the construction of permanent colonies on the Moon and Mars. You won't want to miss that conversation. Show notes: [00:03:59] Dawn opens our interview mentioning that Michael grew up in Minnesota in a small farming community, asking if it's true that he sometimes had to do chores in 20- to 30-degree weather. [00:06:50] Dawn asks if it is true that Michael fell in love with science at a young age, even building telescopes at the age of 11. [00:08:00] Dawn asks Michael what it was that led him to become so fascinated with space specifically. [00:08:58] Dawn asks if Michael ever thought about becoming an astronaut. [00:10:09] Ken asks if it is true that Michael was a big reader as a child. [00:11:21] Dawn asks Michael to talk about his childhood athletic interests. [00:11:55] Dawn asks how it was that a high school quarterback from a small town in Minnesota ended up at university in the United Kingdom. [00:13:38] Ken asks Michael what years he worked at NASA Ames Research Center. [00:14:51] Ken mentions that when Michael was at NASA Ames, he did work collecting molecular and physiologic assessments of humans using NASA's 20-G centrifuge. Ken asks Michael to talk about the centrifuge and how he used it in his studies of hypergravity. [00:17:49] Ken comments on the fact that pieces of equipment like NASA's 20-G centrifuge are a precious scientific resource, and when they cease functioning, unfortunately, they are unlikely to be replaced. [00:19:40] Ken and Michael discuss the fact that microgravity, despite being one of the most pressing effects on astronaut health, is the one of the least addressed problems in human spaceflight. [00:21:48] Ken explains that Michael is the founder, CEO and Chief Scientific Officer of a company called Sovaris Aerospace, which is focused on assessments and solutions applied to humans in space and extreme environments on Earth. Ken asks Michael where the idea came from to found this company. [00:24:35] Dawn explains that since the human genome was first sequenced, there has been an acceleration of genome-based technologies that have made it possible to consider a person's genetic makeup, both in healthcare and optimizing performance. Dawn asks Michael to talk about the work he does applying genomics to human spaceflight. [00:28:52] Dawn asks about Michael's direction of the molecular profiling and precision medicine efforts for the Golden State Warriors during their record-breaking 73-9 season [00:32:57] Dawn mentions that Michael published a review in the journal Meta...

Are you a resident considering a urology fellowship? How do you choose the right subspecialty, and how can effective mentorship help you make the right decision? In collaboration with the Society of Women in Urology (SWIU), this episode of BackTable Urology features practical fellowship advice from Dr. Sevann Helo of Mayo Clinic, Dr. Jay Simhan of Temple University, and guest host Dr. Helen Bernie of Indiana University. --- SYNPOSIS The three leaders in academic urology cover essential topics such as choosing the right fellowship program, finding strong mentorship, and balancing personal and professional life. This episode also offers transparency into the application process. The conversation also delves into the nebulous differences between ACGME and non-ACGME fellowships. This episode is an excellent starting point for practical advice for residents considering this pivotal step in their urology careers. --- TIMESTAMPS 00:00 - Introduction03:07 - Differences Between Residency and Fellowship07:02 - Building a Competitive Fellowship Application11:09 - Pros and Cons of Pursuing a Fellowship16:08 - Accredited vs. Non-Accredited Fellowships20:30 - Choosing the Right Fellowship Program27:31 - Importance of Fellowship Fit28:46 - Evaluating Candidates Beyond Portfolios30:03 - Letters of Recommendation34:56 - Handling Fellowship Challenges38:28 - Gender Diversity in Urology43:31 - Balancing Family and Fellowship50:09 - Concluding Thoughts --- RESOURCES Society of Women in Urologyhttps://swiu.org/home.aspx

Bakers, breadlovers, even purported health information authorities such as the Mayo Clinic all spread the claim that all the problems associated with consumption of foods made of wheat are eliminated or significantly reduced by sourdough fermentation. Is this true?In this episode of the Defiant Health podcast, Let's take each of those claims made, one by one, and examine the evidence to see if there is any truth behind them. _________________________________________________________________________________For BiotiQuest probiotics including Sugar Shift, go here.A 15% discount is available for Defiant Health podcast listeners by entering discount code UNDOC15 (case-sensitive) at checkout.*_________________________________________________________________________________Get your 15% Paleovalley discount on fermented grass-fed beef sticks, Bone Broth Collagen, low-carb snack bars and other high-quality organic foods here.* For 12% off every order of grass-fed and pasture-raised meats from Wild Pastures, go here.Support the showBooks: Super Gut: The 4-Week Plan to Reprogram Your Microbiome, Restore Health, and Lose Weight Wheat Belly: Lose the Wheat, Lose the Weight and Find Your Path Back to Health; revised & expanded ed

Dr Rafael Fonseca from Mayo Clinic in Phoenix, Arizona, discusses datasets from the 2024 ASH meeting on the management of newly diagnosed and relapsed/refractory multiple myeloma. CME information and select publications here.

“And one year, Ariel [Detergent] was, like, you know that 95 % of the people in India still think laundry is a woman's job. And Ariel was just, like, gosh, that doesn't seem like it's, this was 2017 or ‘18 at the time, [and] they're like, that doesn't seem right. Like, it's, haven't we all moved past that? So they created a campaign they called ‘Share the Load.' And what they did is they went out there and they advocated a hashtag, #sharetheload with, for everybody in the family to help with the laundry. It shouldn't just be mom's job anymore. And of course, this kind of air cover for someone who is burdened with this task would just elicit a huge thank you because you're just helping to make their lives better, and you haven't done a darn thing. It's not about the product. It's positioning. Yeah, it's, like, ‘here's what we know you care about, and so we're going to prove that we care about you because we care about that.' Sales went up 76%.” – Reid HolmesThis episode's guest has spent over thirty years leading the creative departments of some of the best ad agencies in America. His idea for H&R Block, “You Got People,” garnered four million new clients, and his work changed the trajectory of brands like Burger King, The Mayo Clinic, KeyBank, and many others. He also has multiple public-speaking awards as he helps audiences gain a deeper understanding of how clarity creates impact. He's won almost every award in advertising and has been featured in The New York Times, Adweek, Advertising Age, Forbes, and Communication Arts.But as his kids started graduating, he realized he wanted to leave a legacy. He found an approach that inspires businesses, marketing teams, and those they wish to attract. His #1 best-selling book, Appreciated Branding: Transform Your Brand from Ignored to Irreplaceable, has become a go-to mature-brand playbook. His name is Reid Holmes, and he'll be sharing his perspective on advertising today, how brands can use sound to stand out and be more memorable, and where he thinks things will go from here. If you're looking to boost your brand, you won't want to miss this one!As always, if you have questions for my guest, you're welcome to reach out through the links in the show notes. If you have questions for me, visit audiobrandingpodcast.com where you'll find a lot of ways to get in touch. Plus, subscribing to the newsletter will let you know when the new podcasts are available along with other interesting bits of audio-related news. And if you're getting some value from listening, the best ways to show your support are to share this podcast with a friend and leave an honest review. Both those things really help – and I'd love to feature your review on future podcasts. You can leave one either in written or in voice format from the podcast's main page. I would so appreciate that.(0:00:00) - The Power of Audio in AdvertisingOur conversation begins with a look back at the early memories that sparked Reid's love of sound, which include his father's copy of the famous War of the Worlds broadcast. “You picture these big, huge Martian creatures that are described,” he says, “and they're coming down through New Jersey and the whole country was freaking out. And it was Orson Welles, who has the pipes for audio.” He tells us more about his family's history in advertising and about how it led to his own career. “I was like, well, my mom was in advertising and my uncle's doing really well in it,” Reid explains. “I should give it a shot because it seems like it runs in the family, and maybe I'd be pretty good at it.”(0:13:02) - The Evolution of Radio...

Send us a textToday's guest is Adrienne Lloyd, MHA, FACHE—founder and CEO of Optimize Healthcare, where she helps medical organizations build empowered teams and sustainable operations without burnout. With over 20 years of experience, including executive leadership roles at the Mayo Clinic and Duke Health, Adrienne brings a deep understanding of what makes healthcare systems thrive. She's also the creator of the Day Zero Blueprint™, a transformative framework for leaders looking to reset their strategy, culture, and execution. Adrienne is a nationally recognized speaker, coach, and host of MGMA's Women in Healthcare podcast, where she champions authentic leadership and systemic change.She and I discuss a multitude of leadership topics including lean and Six Sigma, leading change and turnarounds and financial literacy for physicians and clinicians. She shares from her many years of experience in running medical groups and consulting to them in her practice.Please Follow or Subscribe to get new episodes delivered to you as soon as they drop! Visit Jill's company, Health e Practices' website: https://healtheps.com/ Subscribe to our newsletter, Health e Connections: http://21978609.hs-sites.com/newletter-subscriber Want more content? Find sample job descriptions, financial tools, templates and much more: www.MedicalMoneyMattersPodcast.com Purchase your copy of Jill's book here: Physician Heal Thy Financial Self Join our Medical Money Matters Facebook Group here: https://www.facebook.com/groups/3834886643404507/ Original Musical Score by: Craig Addy at https://www.underthepiano.ca/ Visit Craig's website to book your Once in a Lifetime music experience Podcast coaching and development by: Jennifer Furlong, CEO, Communication Twenty-Four Seven https://www.communicationtwentyfourseven.com/

"You don't have to live with daily migraines, eye strain, or screen fatigue—sometimes, the right lenses can change everything."Today we are joined by Dr. Maria Della Porta, Founder of Della Porta Eyecare to explore an innovative solution for patients experiencing chronic migraines, eye strain, neck tension, and computer vision syndrome: the Neurolens.Dr. Della Porta shares how this advanced lens technology—originally developed in collaboration with the Mayo Clinic—has helped patients reduce symptoms and reclaim quality of life. You'll hear the inspiring story of a young woman whose debilitating migraines were significantly reduced after being fitted with Neurolenses, and learn how these lenses work by correcting misalignments in the visual system.We also discuss how Neurolens compares to blue light glasses, when prism lenses are needed, and how optometrists determine the best treatment for patients struggling with visual symptoms.If you or someone you know suffers from headaches, visual fatigue, or eye discomfort, this episode opens the door to new possibilities—and faster relief.(00:00) Intro(00:41) Meet Dr. Maria de Laporta(01:27) Optometrist vs. Ophthalmologist: Understanding Your Eye Doctor(03:38) Neurolens: Proprietary Technology for Migraines & Headaches(05:45) It Could Be Your Eyes: Recognizing Symptoms Isn't "Normal"(08:17) A Transformative Patient Story: Regaining Functionality(09:49) Identifying the Right Candidate: Muscle Imbalance and Symptoms(11:32) Binocular Vision Dysfunction: A TikTok and Instagram Trend(14:02) Prism Explained: Addressing Misalignment Without Fear(15:10) Neurolenses, Vision Therapy or Surgical Consult?(21:13) Neurolens for Progressive Lenses and Brain Injury Patients(24:05) Brain Injury Patients and Neurolenses(26:19) Neurolenses: Game Changer or Not?Check out our Digital Programs4D Built for LifeStart your FREE TRIAL today 4D Built to Read Digital ProgramConcussion RecoveryBuilt to DriveFollow us at 4D Vision Gym on Facebook and Instagram @4dvisiongymvt for the latest news and updates. DM us if you have any Vision Therapy related questions - you may hear the answer in a future episode!If you enjoyed this show, please rate, review, and subscribe on Apple Podcasts, Spotify, or wherever you get your podcasts. We really appreciate your support!Send us a screenshot of your review and receive 10% off any one of our 4D Vision Gym products or services. And if your friends or family are experiencing inexplicable challenges, refer them to this podcast and tell them, “It Could Be Your Eyes.”

Dr Lindsey Roeker from Mayo Clinic in Rochester, Minnesota, discusses recent updates on available and novel treatment strategies for chronic lymphocytic leukemia. CME information and select publications here.

Kenny Wallace discusses his trip to the Mayo Clinic.#nascar #racing #kennywallace #mayoclinicBrought to you by JEGS! Click here: http://jegs.ork2.net/rQ9Oy5Use Promo Code DEALS To Save Up To 50% OFF Sitewide! Shop Doorbusters, Stackable Savings & 1,000's of Deals at JEGS!JEGS has been in business since 1960.Racers selling to racers.Focusing on American Muscle – but also big product line of automotive tools, garage gear & other performance parts.JEGS is well established with racers of all kinds, including the NHRA, bracket racing, circle track & more!Free shipping on orders over $199.Unrivaled expertise from techs.Millions of parts for every car person's needs.

William W. Mayo immigrated in 1846, married and moved to Minnesota Territory. He was a surgeon in the Union Army in Rochester, Minnesota. In 1864 he opened his first medical practice. He was joined by both sons. They cared for survivors of a tornado, and with the help of Mother Alfred Moes and two hospitals formed the Mayo Clinic. Now, over 7,300 physicians and scientist, they saw 1.3 million patients in 2022. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Sharing an episode of “What It's Like to Be…” from author Dan Heath. On the podcast, Dan explores the world of work, one profession at a time, and interviews people who love what they do. He finds out: What does a couples therapist think when a friend asks for relationship advice? Is a Secret Service Agent supposed to pretend like they're not there when they're around the president? What are the 3 clocks that govern the life of a long-haul truck driver? If you've ever met someone whose work you were curious about, and you had 100 nosy questions but were too polite to ask… this is the show for you. In this preview, Dr. Alfredo Quiñones-Hinojosa (“Dr. Q”), a brain surgeon at the Mayo Clinic, describes his work: zapping parts of the brain to know where to cut, operating a mouth-controlled microscope, and carrying the weight of life-or-death decisions. How do you preserve a mathematician's expertise when removing tumors? And how did Dr. Q go from picking tomatoes to performing brain surgery? You can listen to more episodes of What It's Like to Be here! Learn more about your ad choices. Visit podcastchoices.com/adchoices