Podcasts about Mayo Clinic

August 4, 2026: Your daily rundown of health and wellness news, in under 5 minutes. Today's top stories: Mayo Clinic publishes studies advancing the science of senescent "zombie" cells, identifying new biomarkers of biological aging to build the foundation for targeted longevity therapies Apple reportedly positions future smart glasses as a health and fitness device, hiring a product leader to extend its wearables health strategy beyond the Apple Watch Nike launches Hybrid, a new footwear platform built for hybrid training and racing, signaling long-term investment in fitness's fastest-growing category More from Fitt: Fitt Insider breaks down the convergence of fitness, wellness, and healthcare — and what it means for business, culture, and capital. Subscribe to our newsletter → insider.fitt.co/subscribe Work with our recruiting firm → https://talent.fitt.co/ Follow us on Instagram → https://www.instagram.com/fittinsider/ Follow us on LinkedIn → linkedin.com/company/fittinsider Reach out → insider@fitt.co

Host: Darryl S. Chutka, M.D.  Guest: Josh P. Wiedermann, M.D. Neck masses in children are commonly seen in a primary care practice. Fortunately, most are benign, although serious causes, including malignancy, always remain a possibility. Based on medical history, physical examination, and occasionally imaging studies, the cause is usually able to be identified. What are some key elements consistent with a benign neck mass? When does the management consist of watchful waiting and which ones are concerning and should warrant a prompt referral? These are questions I'll be asking my guest, Dr. Josh Wiedermann, Division Chair of Pediatric Otorhinolaryngology at the Mayo Clinic as we discuss “Pediatric Neck Masses”.  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 

More people are turning to AI chatbots with health questions, and they're getting quick, confident answers. But how much should you actually trust what AI tells you? In this episode, we hear from two doctors about whether AI can really help patients become more informed, and when you definitely still need a human doctor.  You'll hear from both Dr. Matthew Callstrom from Mayo Clinic and Dr. Celine Gounder from CBS News and KFF Health News.   Learn more about our guest(s): https://www.theNewsWorthy.com/shownotes Join us again for our 15-minute daily news roundups every Mon-Fri!  Become an INSIDER and get ad-free episodes here: https://www.theNewsWorthy.com/insider Get The NewsWorthy MERCH here: https://www.theNewsWorthy.com/merch Sponsors: For a limited time, get 60% off your first order, plus free shipping and free treats for life, when you head to Smalls.com/NEWSWORTHY. Search Whatnot—in the App Store, download, and you can sign-up and start selling right away! To advertise on our podcast, please email: ad-sales@libsyn.com

- Anthony Fauci's post-hearing fallout intensifies as critics challenge his pandemic record, media protection and attempts to place government “science” beyond public scrutiny. - Mayo Clinic research on second opinions shows why medical conclusions must remain open to challenge, with most patients receiving a revised, clarified or completely different diagnosis. - Dr. Jeff Barke and Joanne Thomas demand accountability for COVID mandates, censorship and nursing-home isolation after Fauci repeatedly invokes the Fifth Amendment before Congress. - U.S. operations against Iran face heavy political criticism despite flying fewer missions than the Obama administration launches during its intervention in Libya. - Daily marijuana use surpasses cigarette smoking as experts clash over high-potency cannabis, addiction risks and the rapid expansion of THC beverages. Make the switch to NEWSMAX today! 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As healthcare continues its transition toward value-based care, clinical decision support (CDS) is becoming an essential tool for improving appropriate utilization while reducing administrative burden. On this episode, guest hosts Dr Sandy Rolfe (Optum, WEDI Genomics Workgroup) and Julie Brown-Georgi (AMA, WEDI's Value-Based Care Workgroup) interview Rachael Hulshizer from Mayo Clinic and Elizabeth Zobel from CareSelect® Lab to discuss how EHR-integrated, point-of-order CDS is transforming laboratory and genomic test ordering through evidence-based guidance, interoperability standards, and actionable analytics. The conversation explores how structured data, FHIR-enabled exchange, and clinician-centered workflows can help advance stewardship, improve patient care, and support the future of precision medicine

In this episode of the Oncology Brothers podcast we continued our treatment algorithm series, focusing on early relapsed/refractory multiple myeloma (RRMM). We were joined by Dr. Shaji Kumar, a myeloma specialist from the Mayo Clinic, who shared his insights into current evidence-based treatment strategies for patients whose disease has progressed after frontline therapy.   Key topics discussed included: The current standard of care for frontline multiple myeloma, including quadruplet therapy and maintenance strategies The role of CAR T-cell therapy and bispecific antibodies, including teclistamab and talquetamab, in early relapsed/refractory multiple myeloma Treatment selection based on patient age, prior therapy, drug exposure, and disease biology The importance of shared decision-making and incorporating patient preferences into treatment planning Recent clinical trial data and emerging therapies shaping the future of multiple myeloma care This episode provides practical insights into managing early relapsed/refractory disease and navigating today's evolving treatment landscape.   Listen us on: Spotify: https://open.spotify.com/show/31BXhY9FM4gPWG10WgE11o  Follow us on social media: X/Twitter: https://x.com/oncbrothers ⁠Instagram: https://www.instagram.com/oncbrothers Website: https://oncbrothers.com/    Subscribe for more expert discussions on multiple myeloma, hematologic malignancies, cellular therapies, bispecific antibodies, and precision oncology. #MultipleMyeloma #CART #BispecificAntibodies #Hematology #Oncology

In today's episode, we spoke with Tanios S. Bekaii-Saab, MD. Dr Bekaii-Saab is the David F. and Margaret T. Grohne Professor of Novel Therapeutics for Cancer Research I, at the Mayo Clinic College of Medicine and Science, the division chair of Hematology/Medical Oncology at Mayo Clinic, and co-leader of the Advanced Clinical and Translational Science Program and the disease group leader for Gastrointestinal Cancers for the Mayo Clinic Comprehensive Cancer Center in Phoenix, Arizona.In our exclusive interview, Dr Bekaii-Saab discussed findings from the final analysis of cohort 3 of the phase 3 BREAKWATER trial (NCT04607421), which were presented at the 2026 ASCO Annual Meeting. These data showed that encorafenib (Braftovi) plus cetuximab (Erbitux) and FOLFIRI (leucovorin, 5-fluorouracil, and irinotecan) significantly improved outcomes compared with standard of care in patients with BRAF V600E–mutant metastatic colorectal cancer (mCRC), building on previously reported data from the trial that led to the February 2026 full FDA approval of encorafenib plus cetuximab and modified FOLFOX6 (leucovorin calcium, fluorouracil, and oxaliplatin) for this patient population. He also highlighted promising bispecific agents targeting VEGF and PD-1, as well as the promise of KRAS G12C inhibitors like calderasib (MK-1084) and sotorasib (Lumakras). Finally, he emphasized that minimal residual disease testing is prognostic and potentially predictive, and can aid in personalized mCRC management.

Show NotesContactRobert Sefcik, Executive Director, Jacksonville Sports Medicine Program (JSMP), 3563 Phillips Highway, Building E, Suite 502, Jacksonville, FL 32207Robert.sefcik@bmcjax.com  |  904-202-4332Florida Alliance for Sports Medicinehttps://fasmed.fadss.orgDr. Gul Dadlaini Nemours.org 407-650-7715Dr. Matthew Martinez is a cardiologist in Jacksonville, Florida at the Mayo Clinic. He received his medical degree from Mayo Clinic College of Medicine and Science and has been in practice for more than 20 years. He has expertise in treating hypertension & high blood pressure, cardiomyopathy, heart failure, among other conditions DisclaimerGuests of the show are stakeholders in youth sports safety. Views expressed are those of the guest and not necessarily those of the employees, administration, or associated staff of JSMP, and do not imply any endorsement of any product, service, or opinion. All material presented is provided for information only and should not be construed as professional advice. Any use of this podcast without the express written consent of JSMP or FASMED is strictly prohibited. The Youth Sports Safety Update is produced by the Jacksonville Sports Medicine Program, which is dedicated to youth sports safety through awareness, advocacy, and injury prevention. Thank you.

Cheryl Sew Hoy, CEO of Tiny Health, built a gut microbiome testing platform from her living room with a newborn, a toddler, and a co-founding spouse. In this episode, she shares the real mechanics of scaling a science-driven health company while designing a support system that actually works.- Validated market demand by testing search keywords around baby eczema and allergies, then used those insights to shape paid and organic channel strategy across Google and Meta- Built scientific credibility by recruiting advisors from Mayo Clinic, Johns Hopkins, and UCSF to fill expertise gaps and establish trust in a category where consumers and doctors alike lacked awareness- Negotiated explicit division of labor at home and hired family members into operational roles, creating a sustainable structure that protected founder bandwidth through three children and a four-times revenue growth yearListen on Apple Podcasts, Spotify, or Amazon Music. Follow Sales Talk for CEOs so you never miss an episode.

Host: Darryl S. Chutka, M.D.  Guest: Karthik Ravi, M.D.  Eosinophilic Esophagitis is often misdiagnosed or undiagnosed in primary care settings, yet it's a common cause of esophageal symptoms. It's commonly mistaken for the more common gastroesophageal reflux disease as it can present with symptoms of reflux and dysphagia. How can we differentiate eosinophilic esophagitis from reflux esophagitis? What's needed to establish a diagnosis? What are the management options and what's the long-term outlook for those with the condition? These are some of the questions I'll be asking my guest Dr. Karthik Ravi, a gastroenterologist at the Mayo Clinic as we discuss “Eosinophilic Esophagitis”.  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 

You’ve probably heard the words ‘biofeedback' and ‘neurofeedback' floating around the internet. And you're also probably wondering what they mean and if they're worth your time and money when you have a vestibular disorder. I'm answering all of that in this episode! Biofeedback is a type of mind-body technique to control some of the body's function. And neurofeedback is a type of biofeedback that measures and records brainwaves. As always, I've got research and scenarios for us to talk through to help this really land. They're probably not the first thing you want to invest in and there are even less expensive options that are equally or more effective which I share more about in the episode. Buckle up and let's get a little nerdy with this one! In this episode, we'll dig into: What biofeedback is and how it works What the main types of biofeedback are What neurofeedback is and how it relates to biofeedback The difference between active and passive neurofeedback The two main models of biofeedback that exist What to expect in a biofeedback session What biofeedback is considered effective for Types of neurofeedback and biofeedback sessions, devices, and apps available How to find a qualified biofeedback provider What questions to ask before committing to either option If you want to go even deeper with what you heard in this episode, we have coaching calls specifically about biofeedback and neurofeedback available in Vestibular Group Fit. Biofeedback is a tool, not a cure. But if you’re curious, informed, and financially comfortable exploring it, it absolutely can have a place in your vestibular toolkit. Links Mentioned: Vestibular Group Fit (code GROUNDED at checkout for 15% off!): https://thevertigodoctor.com/vestibular-group-fit Certification from the Association for Applied Psychophysiology and Biofeedback (AAPB) site has an option to find a practitioner: https://aapb.org/Find_a_Practitioner  Hearthmath: https://www.heartmath.com/  Resperate (FDA approved for blood pressure and stress): https://resperate.com  Leva (FDA approved for pelvic floor): https://levacares.com/  Prism (FDA approved for PTSD): https://www.graymatters-health.com/prism-for-ptsd  Finding a provider International society for neuroregulation and research: https://isnr.org/ Biofeedback certification international alliance: https://www.bcia.org/ Free Resources: ⁠The 4 Steps to Managing Vestibular Migraine: https://thevertigodoctor.myflodesk.com/cb5js0y78n ⁠The PPPD Management Masterclass⁠: https://thevertigodoctor.myflodesk.com/new-pppd ⁠What your Partner Should Know About Living with Dizziness⁠: https://thevertigodoctor.myflodesk.com/partnership ⁠The FREE Mini VGFit Workout⁠: https://thevertigodoctor.myflodesk.com/minifit ⁠The FREE POTS – safe Workouts⁠: https://thevertigodoctor.myflodesk.com/pots Connect with Dr. Madison (@TheVertigoDoctor): https://instagram.com/thevertigodoctor Work with Dr. Madison: For 1:1 Vestibular Rehabilitation Therapy, email madison@thevertigodoctor.com Otherwise, I'll see ya in Vestibular Group Fit! Connect with Dr. Jenna (@dizzy.rehab.therapist): https://www.instagram.com/dizzy.rehab.therapist/ Learn about the Oak Method: http://thevertigodoctor.com/why-vestibular-group-fit Love what you heard?Consider leaving a review on your favorite podcast platform to help us reach more vestibular warriors like you! This podcast is for informational purposes only and may not be the best fit for you and your personal situation. It shall not be construed as medical advice. The information and education provided here is not intended or implied to supplement or replace professional medical treatment, advice, and/or diagnosis. Always check with your own physician or medical professional before trying or implementing any information read here. Citations Frank, D. L., Khorshid, L., Kiffer, J. F., Moravec, C. S., & McKee, M. G. (2010). Biofeedback in medicine: who, when, why and how?. Mental health in family medicine, 7(2), 85–91. Mayo Clinic. “Biofeedback – Mayo Clinic.” Mayoclinic.org, 18 Mar. 2023, www.mayoclinic.org/tests-procedures/biofeedback/about/pac-20384664. Marzbani, H., Marateb, H. R., & Mansourian, M. (2016). Neurofeedback: A Comprehensive Review on System Design, Methodology and Clinical Applications. Basic and clinical neuroscience, 7(2), 143–158. https://doi.org/10.15412/J.BCN.03070208 Bazzana, F., Finzi, S., Di Fini, G., & Veglia, F. (2022). Infra-Low Frequency Neurofeedback: A Systematic Mixed Studies Review. Frontiers in human neuroscience, 16, 920659. https://doi.org/10.3389/fnhum.2022.920659 Duke, G., Yotter, C. N., Sharifian, B., Duke, G., & Petersen, S. (2024). The effectiveness of microcurrent neurofeedback on depression, anxiety, post-traumatic stress disorder, and quality of life. Journal of the American Association of Nurse Practitioners, 36(2), 100–109. https://doi.org/10.1097/JXX.0000000000000945 Cleveland Clinic. “Biofeedback: What Is It & Procedure Details.” Cleveland Clinic, 21 Dec. 2020, my.clevelandclinic.org/health/treatments/13354-biofeedback. biofeedback and neurofeedback, biofeedback vs neurofeedback, vestibular group fit, VGF, vestibular disorders, chronic dizziness, PPPD, nervous system regulation, migraine management, stress relief, alternative therapies, holistic approach, living with vestibular migraine, living with vertigo, migraine toolkit, vestibular disorder treatment

Welcome to the Oncology Brothers podcast! In this episode, we dived into the latest advancements in multiple myeloma treatment, focusing on the practice changing ENDURANCE trial. Joined by esteemed guests Dr. Shaji Kumar and Dr. Vincent Rajkumar from Mayo Clinic, they discussed the new time limited approach being the standard of care for maintenance therapy in standard-risk multiple myeloma patients.   Key topics include: Overview of the ENDURANCE trial and its implications for clinical practice The significance of limiting lenalidomide maintenance therapy to two years The role of minimal residual disease (MRD) testing in treatment decisions Insights on high-risk cytogenetics and future directions for therapy   This episode is a must-listen for community oncologists and anyone interested in the evolving landscape of cancer treatment. Tune in to learn how these findings can impact patient care and improve outcomes!   Listen us on: Spotify: https://open.spotify.com/show/31BXhY9FM4gPWG10WgE11o  Follow us on social media: X/Twitter: https://x.com/oncbrothers ⁠Instagram: https://www.instagram.com/oncbrothers  Website: https://oncbrothers.com/    Don't forget to like, subscribe, and check out our other episodes for more discussions on treatment algorithms, conference highlights, and challenging cases in oncology. #MultipleMyeloma, #ENDURANCE, #Lenalidomide, #MRD, #OncologyBrothers

Can you spend over $100,000 a year on your health and still get worse? That's exactly what happened to a patient of Dr. Robert Todd Hurst, board-certified preventive cardiologist and founder of HealthspanMD. In his 60s, elite fitness, 16% body fat, 100th percentile muscle mass, an A1C of 5.0 by every visible measure, this man was doing everything right. But a repeat CT angiogram with plaque composition analysis told a different story: his soft plaque volume increased from 259 to 290 cubic millimeters in a single year. The dangerous, reversible kind of plaque was growing. In this mini Healthspan Podcast episode, Dr. Hurst breaks down why even the most expensive, cutting-edge care can fail… no genetic testing to uncover root causes, no adjustments based on feedback, and a regimen built on the latest treatments instead of the proven foundations that actually stop and reverse artery disease. Heart disease reversal isn't about spending more. It's about knowing your root causes, personalizing your plan, and adjusting based on real data. If you've been diagnosed with heart disease, have a high calcium score, or want to know whether your current plan is actually working, this one is worth your time. About the Guest Dr. Robert Todd Hurst, MD, FACC, FASE, is a board-certified preventive cardiologist, former Mayo Clinic physician, and founder of HealthspanMD. His mission is simple: no one should die of a heart attack, ever. Through a proactive, precision-medicine approach, he helps patients identify hidden risks, address root causes, and prevent or reverse heart disease while extending healthspan and quality of life. Learn more: Join.HealthspanMD.com Key Timestamps 00:03 – The patient spends over $100,000 per year on health optimization 00:45 – Elite fitness, low body fat, and excellent metabolic markers 01:20 – Understanding CT angiograms and plaque composition analysis 02:05 – Why soft plaque matters more than calcified plaque 03:00 – The shocking discovery that artery disease was getting worse 03:55 – Why increasing soft plaque volume is unacceptable 04:45 – The missing pieces: genetics, cholesterol, insulin resistance, and inflammation 05:40 – Why expensive treatments failed to address the root causes 06:20 – The difference between leading-edge care and effective care 07:05 – Why healthcare is failing despite more spending 07:40 – The three biggest problems with modern healthcare 08:05 – Why HealthspanMD focuses on proactive, personalized, healthspan-focused care 08:50 – The mission to transform healthcare and add healthy years to life   This information is for educational purposes only and is not medical advice. Don't make any decisions about your medical treatment without first talking to your doctor.   *Connect* *with* *HealthspanMD* :

Nutrition plays a critical role in cancer care, yet it is often overlooked. Many patients experience weight loss, muscle wasting, treatment-related side effects, and changes in appetite that can affect their ability to tolerate therapy and maintain quality of life. Although nutrition specialists can help manage these challenges, access to specialized nutritional care remains limited in many healthcare settings. An editorial published in Volume 17 of Oncotarget, titled “Artificial intelligence in nutritional oncology: From isolated screening tools to agentic intervention systems,” explores how advances in artificial intelligence (AI) could help address this gap. The editorial was written by Arnab Sarkar and corresponding author Yashbir Singh-Wolkenhauer, who is affiliated with the Department of Radiology, Mayo Clinic, Rochester, Minnesota. Rather than presenting new clinical trial data, the authors outline a future vision in which AI systems move beyond isolated tasks to continuously support nutritional care throughout a patient's cancer journey. Full blog post - https://www.oncotarget.org/2026/07/28/artificial-intelligence-could-transform-nutrition-care-for-cancer-patients/ DOI - https://doi.org/10.18632/oncotarget.28874 Correspondence to - Yashbir Singh-Wolkenhauer - singh.yashbir@mayo.edu Abstract video - https://www.youtube.com/watch?v=sVKhRSr5xaY Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28874 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, artificial intelligence To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us on social media: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Comparing Marfan Syndrome, Loeys-Dietz Syndrome, and Vascular EDS   Guest: Juan Bowen, M.D. Host: Paul Friedman, M.D.   Marfan syndrome, Loeys-Dietz syndrome, and vascular Ehlers-Danlos syndrome are clinical problems seen in an aortic clinic. Thoracic aortic aneurysm is a common feature, but the three conditions differ in the severity of aortic and arterial disease and in the types of extracardiac problems that require management. Making an accurate diagnosis is an essential first step in their successful management.   Topics Discussed: What mutations cause Marfan syndrome, Loeys-Dietz syndrome, and the vascular Ehlers-Danlos syndrome? What is the natural history of these three conditions? How is aortic and vascular disease managed in these three conditions? What are the non-cardiac problems most often encountered in these three conditions?   Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode.   Podcast episode transcript found here.   Recorded on: 17-February-2026

Dr. Bill Morice is the President and CEO of Mayo Clinic Labs and a professor of Pathology at Mayo Clinic. Dr. Morice is also a longtime contributor on The CGP. This week he breaks down what, exactly, cyclosporiasis is and how long we can expect it will hang around here in the U.S... more specifically, in California. Measles - reported cases are growing exponentially and Dr. Morice sheds light on why. The Christopher Gabriel Program ----------------------------------------------------------- Please Like, Comment and Follow 'The Christopher Gabriel Program' on all platforms: The Christopher Gabriel Program is available on the KMJNOW app, Apple Podcasts, Spotify, YouTube or wherever else you listen to podcasts. --- The Christopher Gabriel Program | Website | Facebook | X | Instagram | --- Everything KMJ KMJNOW App | Podcasts | Facebook | X | Instagram See omnystudio.com/listener for privacy information.

Helpig others is a two-way street. I'm not sure which feels better, being helped gives you a big sense of relief and helping others gives you a big sense of being a part of something good. Here's a quick episode on helping. Thanks for listening and helping me get the word out about my podcast. https://www.TheWorkLady.com  Jan McInnis is a top change management keynote speaker, comedian, and funny motivational speaker who helps organizations use humor to handle change, build resilience, and strengthen leadership skills. With her laugh-out-loud stories and practical tips, Jan shows audiences how humor isn't just entertainment—it's a business skill that drives communication, connection, and stress relief.   A conference keynote speaker, Master of Ceremonies, and comedy writer, Jan has written material for The Tonight Show with Jay Leno as well as radio, TV, and syndicated cartoon strips. She's the author of two books—Finding the Funny Fast and Convention Comedian—and her insights on humor in business have been featured in The Wall Street Journal, The Washington Post, and The Huffington Post. For over 25 years, she has been helping leaders and teams discover how to bounce back from setbacks, embrace change, and connect through comedy.   Jan has delivered keynote speeches at thousands of events nationwide, from the Federal Reserve Banks to the Mayo Clinic, for industries that include healthcare, finance, government, education, women's leadership events, technology, and safety & disaster management. Her client list features respected organizations such as: Healthcare: Mayo Clinic, Kaiser Permanente, Abbott Pharmaceuticals, Health Information Management Associations, Assisted Living Associations Finance: Federal Reserve Banks, Merrill Lynch, Transamerica Insurance, BDO Accounting, American Institute of CPAs, credit unions, banking associations Government: U.S. Air Force, Social Security Administration, International Institute of Municipal Clerks, National League of Cities, public utilities, correctional associations Women's Leadership Events: Toyota Women's Conference, Go Red for Women, Speaking of Women's Health, Soroptimists, Women in Insurance & Financial Services Education: State superintendent associations, community college associations, Head Start associations, National Association of Elementary and Middle School Principals Safety & Disaster: International Association of Emergency Managers, Disney Emergency Management, Mid-Atlantic Safety Conference, risk management associations   Her background as a Washington, D.C. marketing executive gives her a unique perspective that blends business acumen with stand-up comedy. Jan was also honored with the Greater Washington Society of Association Executives "Excellence in Education" Award. Along with her podcast Finding the Funny: Leadership Tips from a Comedian, Jan also produces Comedian Stories: Tales From the Road in Under 5 Minutes. Whether she's headlining a major convention, hosting a leadership retreat, or teaching resilience at a safety conference, Jan's programs give audiences the tools to laugh, learn, and lead.  

Most adults who smoke want to quit, and about half try to do so in any given year, yet fewer than one in ten succeed. That persistent gap between intention and outcome is one of the central challenges in public health, and it's exactly the kind of problem that calls for new thinking about how to communicate with people to support behavior change.  Dr. Amanda Graham has been a leading force in doing just that in her role as chief health officer at Truth Initiative, the nation's largest non-profit public health organization dedicated to preventing addiction among young people and helping people of all ages to quit tobacco. On this episode of Raise the Line from Elsevier, Dr. Graham, who holds a PhD in clinical health psychology and has done 25 years of NIH-funded research focused on technology-based cessation interventions, helps us understand the interplay between behavioral science and digital communications in the field. "A well-timed message can really be powerful in interrupting what for many people is kind of an automatic behavior, especially via text, which data tell us is an extraordinarily powerful modality,” she explains to host Lindsey Smith.  Tune-in to understand where the field is heading, and to learn about: Why "push" technology may work better than apps and websites when it comes to breaking automatic behaviors; How the rise of e-cigarettes, nicotine pouches, and heated tobacco has scrambled decades of public health messaging; How highschool smoking rates plunged from over 30% to less than 2%. Mentioned in this episode: Truth Initiative Program with Mayo Clinic If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., president and CEO of Mayo Clinic Laboratories, to discuss the Protecting Access to Medicare Act (PAMA) and a recent Cyclospora outbreak making headlines. Later, Dr. Pritt welcomes Juliana Perez Botero, M.D., a Mayo Clinic hematologist, to explore innovative testing approaches for bleeding disorders.PAMA data collection and reform (01:05): With data collection for PAMA underway, Dr. Morice shares the latest on potential updates to the law.Cyclospora outbreak (05:45): Get a microbiologist's perspective on the recent Cyclospora outbreak and learn practical steps to help reduce your risk of infection.The value of laboratory testing for bleeding disorders (08:37): Discover why laboratory testing plays a critical role in the diagnosis and management of patients with bleeding disorders.Innovation for bleeding disorder testing (12:56): Learn how genotype assays are enhancing patient care and how advances in nanotechnology and collaborative research are opening new possibilities for the future.ResourcesMayo Clinic Classical Hematology Conference Bleeding disorders: The right test at the right timeCyclospora Stain, Feces (Mayo ID: CYCL)

In this episode, I sit down with Jody to talk about what life was like when she was dealing with 15 to 28 migraines a month, daily headaches, dizziness, nausea, and overwhelming sensitivity to light, noise, and smells. She shares the long list of things she had already tried, from Mayo Clinic and Duke to Botox, triptans, Topamax, Ajovy, specialists, and countless other treatments, before she found a different path. We talk about what changed, what healing looked like for her in real life, and how she went from spending days in a dark room to building a successful baking business and getting her energy, confidence, and freedom back. If you're ready to address the root drivers of your migraines, you can book a free consultation at the link below: https://www.drlesliecisar.com/apply Free Training: 5 Proven Steps to Being Migraine Free (Even if you think you've already tried everything.) https://www.drlesliecisar.com/5SHMN Connect with us: Website: https://www.drlesliecisar.com/ Free Facebook Group: Healing Migraines Naturally, with Leslie Cisar, ND Ready to try something radically different that actually works? Read more about my approach here: https://www.drlesliecisar.com/map In health,Dr. Leslie Cisar

The Experience Strategy Podcast | theexperiencestrategist.substack.com A nurse whose only job was to hold a patient's hand during a procedure. A debrief with the doctor scheduled before the procedure was even booked. A title accidentally revealed mid-conversation. This episode covers a lot of ground — starting with where healthcare experience strategy stands right now, and ending somewhere that a certain author probably wasn't expecting. What's in This Episode Healthcare is recovering — and the investment is back. After a brutal five-year stretch that left providers burned out and hospital systems in survival mode, Dave sees real momentum returning. Capital is flowing back into healthcare, and what's different this time is a more mature understanding of where technology fits and where it doesn't. AI handling clinical note-taking is the clearest near-term win — freeing physicians from the documentation burden that was eating their limited time with patients. Longer term, the new generation of LLMs built for scientific discovery is accelerating treatment development in ways that weren't possible even three years ago. The problem with scaling human experience. Mayo Clinic and Cleveland Clinic were early adopters of design thinking — writing case studies on patient experience in the 2000s that the whole industry studied. But the business model kept pulling in the other direction: enormous capital expenses, opaque insurance structures, and the relentless pressure to grow. And as Dave puts it, when you scale up a healthcare system, individualized experience gets harder, not easier. That's always true in any category — but the stakes are higher in healthcare. Then a pandemic arrived and survival became the only goal. The better the patient experience, the better the outcomes. Joe has been saying this for years, and the research backs it. The insight is simple but organizationally difficult: healthcare is not a service business. It uses experiences, but it's fundamentally in the transformation business. Every patient walking through the door has an aspiration — some version of going from sick to well. That aspiration, and the experience designed around it, drives outcomes. Geisinger Health System has operationalized this through outcome-based pricing: knee replacement doesn't work, you don't pay. More systems are moving in that direction. Human needs versus patient needs — there's a difference. Aransas's experience at Memorial Sloan Kettering is the episode's anchor story. A procedure booked with a debrief appointment scheduled at the same time — eliminating the anxiety window between test and result. And a nurse whose sole role during the procedure was comfort: one hand on Aransas's hand, one hand on her shoulder. Joe's reframe lands hard: "They didn't just meet your patient needs — they met your human needs." The distinction matters. Patients are still too often seen as collections of symptoms. The shift toward the whole person is coming, but it's uneven. AI's real job in healthcare: offload the routine so humans can be human. The most useful frame for AI in any service category — and healthcare in particular — isn't automation for its own sake. It's freeing the human in the room to be fully present. Checklists, documentation, protocol verification: these are exactly the kinds of cognitive load that drain providers and crowd out the relationship. Aransas makes the point that the "which leg are we operating on?" verification ritual exists because it was a real risk. The goal is to use operations and AI to cover the routine, so providers can put their energy into the part that only humans can do. Trained empathy has a shelf life. Dave traces the arc from "Welcome to Wachovia!" — a scripted greeting that felt like cutting-edge hospitality in its day — to the present moment, where scripted warmth reads as inauthentic almost immediately. Rote empathy, whether from a human or an AI trained to flatter, produces the same result: it rings hollow. Consumers have been through enough now that they can tell the difference. Joe's COVID-era conclusion still stands: "Be human." That's not a soft directive. In an environment where AI handles more and more of the transaction, genuine human presence becomes the differentiator. The tools that made experiences more human are showing their age. Persona building. Journey mapping. Design thinking. These were genuinely useful frameworks, and the industry built real capability around them. But Dave argues they're no longer sufficient. The question isn't how to design a better map — it's how to build what he's calling intelligent experiences: a new framework for the human interface that fits the current environment. He's writing about it now.   Referenced Memorial Sloan Kettering — patient experience design as a model for the category Geisinger Health System — outcome-based pricing for knee replacement procedures Wachovia Bank — early scripted greeting protocols as a case study in what hospitality looked like before it became a liability Have a question for Joe, Dave, or Aransas? Reply to any episode email on Substack — it goes straight to them. The Experience Strategy Podcast is hosted by Dave Norton and Aransas Savas. Subscribe at theexperiencestrategist.substack.com.

In this two-part episode, we welcome Dr. Ruti Sella, who is a cataract, cornea, and refractive surgeon, Associate Professor of Ophthalmology, and Clinical Practice Chair at Mayo Clinic. In Part 1, we explore the evolution of modern cataract surgery, discussing advances in refractive outcomes, premium intraocular lenses, surgical planning, keratoconus, and the emerging role of artificial intelligence in improving precision and personalization of cataract surgery. Together, these episodes combine expert perspective with the latest clinical evidence, offering practical insights into contemporary cataract and refractive surgery. Whether you are a resident, comprehensive ophthalmologist, anterior segment surgeon, or simply interested in advances in ophthalmology, we hope you enjoy both parts of this special series. Subscribe to the podcast:  https://MayoClinicOphthalmology.podbean.com  Follow and reach out to us on X and IG: @mayocliniceye

— What if one of the most powerful tools for improving your health was already at your fingertips? In this episode, we explore the fascinating intersection of artificial intelligence and personal well-being through the themes of Better Health with AI: Your Roadmap to Results with Dr. Earl Campazzi. As AI rapidly transforms the way we live and work, it is also changing how we understand, monitor, and care for our health. Dr. Earl discuss how emerging technologies—from wearable devices and health apps to genetic insights and AI-powered analysis—can help us move from reactive healthcare to proactive wellness. How can we detect health risks earlier? Make more personalized decisions about nutrition, exercise, and longevity? And how do we use these tools wisely while remaining aware of their limitations? Join us for an insightful conversation about the future of preventive medicine, the promise and pitfalls of AI, and how technology can empower us to take a more active role in creating healthier, longer, and more vibrant lives. Valeria sits with Dr. Earl J. Campazzi, Jr — He is the author of  "Better Health with AI: Your Roadmap to Results." Dr. Earl J. Campazzi, Jr., brings over 35 years of clinical experience and four board certifications to his Palm Beach Concierge Practice, bridging traditional medicine with modern technology. A graduate of the University of Pittsburgh School of Medicine, he also holds three degrees from Johns Hopkins University—including a Master of Public Health from the School of Hygiene and Public Health—and an MBA from Duke University. Dr. Campazzi's distinguished career includes serving as Senior Associate Consultant at the Mayo Clinic, Chief Resident in Preventive Medicine at Johns Hopkins, and Medical Director for Palm Beach County's Occupational Health Clinic. As founder of Island Medical Care, he has practiced concierge medicine in Palm Beach since 2006, earning national recognition such as HCA's Top Physician for Patient Satisfaction award, while maintaining staff privileges at leading hospitals including Cleveland Clinic Florida. Passionate about making artificial intelligence accessible to everyone—even those who aren't "tech people"—Dr. Campazzi helps families use simple, practical tools to live longer, healthier lives. Learn more about Dr. Earl J. Campazzi, Jr and his work!

Host: Darryl S. Chutka, M.D.  Guest: Dawn Davis, M.D.  Psoriasis is a health condition commonly seen in primary care but one which has evolved significantly in both how we understand the disease as well as how it's managed. At one time, psoriasis was considered primarily a skin disorder; however, we now know it's part of a systemic inflammatory disease with potential involvement of multiple organ systems. What do we know about the pathophysiology of psoriasis? How does it change our management when we think of it as a systemic disease? What are some of the new treatment options we now have available?  I'll ask these questions and more of my guest as we discuss “Psoriasis”.  My guest for this podcast is Dr. Dawn Davis, Chair of Clinical and Pediatric Dermatology at the Mayo Clinic in Rochester, Minnesota.  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 

The episode reveals a fundamental structural shift in AI deployment: the deliberate decoupling of powerful AI capabilities from accountability and human oversight. This is exemplified by incidents such as a former Mayo Clinic safety lead being fired after flagging a hospital AI tool (Maya) with a significant error rate (up to 67%) and the replacement of nurses by AI for administrative tasks at Montefiore. The trend is further driven by the increasing availability of potent, open-source AI models, like Moonshot's Kimik 3.2, which remove the traditional vendor accountability that was once inherent in software delivery. This detachment is fueled by a desire for speed and cost savings, leading to a critical "governance gap" where AI operates without a robust control layer or "harness." A primary development highlighting this shift is the reported issue with OpenAI's GPT 4.56, which allegedly deleted user files, termed an "honest mistake" by the company. This underscores how AI, even from leading developers, can cause operational damage when unsupervised. The episode points out that historically, software delivery included both vendor liability and human oversight as inherent safeguards. However, the move towards commoditized, freely accessible AI models and open-source releases is intentionally eliminating these checks. Enterprises are also rationalizing this by shifting to local AI models, severing ties with vendors who were previously points of accountability. Supporting this central theme, the episode details how the increasing accessibility of advanced AI models, such as Kimik 3.2, means frontier capabilities are no longer confined to major labs. Furthermore, studies indicate that reliance on AI advice can paradoxically reduce human accuracy and increase overconfidence in incorrect outputs, making human review less effective if not properly structured. This suggests that even human oversight, if not independently rigorous, can be compromised by the very AI it's meant to check. The core value is shifting from the AI model itself to the "harness"—the accountable judgment layer that controls and validates AI actions. For MSPs and IT leaders, this structural shift creates significant operational implications. The erosion of vendor accountability and human oversight means the "harness" is often missing, creating a liability vacuum. Clients may deploy AI without adequate checks, leading to potential errors, data loss, and reputational damage. MSPs are presented with an opportunity to address this by becoming the named, accountable "check" or harness provider. This requires shifting client conversations from AI acquisition to AI accountability, mapping existing unsupervised AI deployments, and offering oversight services as a distinct, valuable offering to mitigate risks for clients and ensure trustworthy AI integration. 00:00 AI Went Free, the Checks Didn't  03:59 Forget the Model — Own the Harness 06:45 You Can't Just Watch It Anymore 10:19 Why Do We Care?  Supported by: Pax8

Save 20% on all Nuzest Products WORLDWIDE with the code MIKKIPEDIA at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comCurranz Supplement: Use code MIKKIPEDIA to get 20% off your first order - go to www.curranz.co.nz  or www.curranz.co.uk to order yours NZ listeners - save 10% off Calocurb by using the code Mikkipedia10 at www.calocurb.co.nzThis week on the podcast Mikki speaks to two researchers, Professor Daniela Hurtado and Dr Regina Castaneda about the interaction between HRT and tirzepatide use. In a conversation led by Regina, they talk about differences that occur as women head through menopause, the role of HRT at mitigating some of these changes and the findings from their paper looking at how hormone therapy might enhance the therapeutic effects of tirzepatide in a postmenopausal population - discussing sex related differences.Maria Daniela Hurtado Andrade, M.D., Ph.D., is from Ecuador where she completed her medical degree at the Pontifical Catholic University. Her curiosity about the causes of obesity led her to pursue doctorate-level training in Physiology and Pharmacology at the University of Florida. Her research focused on the brain's regulation of food intake. After her doctoral training, she completed Internal Medicine training at the University of Pittsburgh Medical Center in Pittsburgh, PA, and Endocrinology Fellowship specialty training at Mayo Clinic in Rochester, MN. She joined Mayo Clinic Staff in 2019.Dr. Hurtado Andrade is interested in understanding obesity's pathophysiology to develop more effective therapeutic interventions. She is part of the Mayo Clinic Precision Medicine for Obesity program. This program aims at developing an individualized approach to the management of obesity and its complications with the goal of improving outcomes. To facilitate the generation of this new knowledge, she has focused her clinical and research efforts on specific populations: perimenopausal women and breast cancer survivors. Dr. Hurtado's contributions and expertise to the field of obesity have been recognized nationally and internationally.Regina Castaneda, MD, serves as a postdoctoral research fellow at Mayo Clinic in Florida. She is also an MSc candidate at Mayo Clinic College of Medicine and Science. Her work centres on women's health topics including obesity, diabetes, and menopause-related metabolic changes.Dr Castaneda has contributed to research examining the effects of tirzepatide on weight loss in postmenopausal women and the potential influence of hormone therapy. She is affiliated with the Division of Endocrinology, Diabetes and Metabolism at Mayo Clinichttps://www.mayoclinic.org/biographies/hurtado-andrade-maria-daniela-m-d-ph-d/bio-20539671https://www.linkedin.com/in/regina-castaneda-md-8b2371358/ Paper: https://www.thelancet.com/journals/lanogw/article/PIIS3050-5038(25)00145-1/abstract Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwilliden

Inflammatory Aortic Aneurysms   Guest: Kenneth Warrington, M.D. Host: Kyle Klarich, M.D.   In this episode of “Interviews With the Experts,” the listener will learn how to identify the common signs and symptoms associated with inflammatory aortic disease, as well as understand the conditions associated with inflammatory aortic aneurysms. Dr. Kenneth Warrington, John F. Finn Minnesota Arthritis Foundation Professor and consultant in rheumatology at Mayo Clinic, reviews the latest imaging techniques and treatments for inflammatory aortic disease.   Topics Discussed: How do patients with inflammatory aortic disease present in clinical practice? Which specific conditions are associated with inflammatory aortic aneurysms? How are inflammatory aortic aneurysms diagnosed? How are patients with inflammatory aortic aneurysms managed?   Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode.   Podcast episode transcript found here.   Recorded on: 15-January-2026  

If you are a senior or elderly person taking benzodiazepines there are things you need to be aware and informed about. Not from a place of fear but of safety.  In this episode, a quick look at how benzodiazepines can affect older adults and a few resources.   One more thing. There is a high number of AI Slop videos on this topic. Some of the presenters are not human. We have a new generation of graduates of the I-fleece-em academy.    You can tell by how much fear they projects and the image of a medical persona. The thumbnail is designed to hook you by engaging in your curiosity or concern about a medication you take.   Please think before you click.    Resources Mentioned:  Over on the Canadian side of the fence, there is a brochure from Canadian Coalition for Senior Mental Health. Simple, easy to read and packed with solid accessible information. Such as if you are taking Benzos, you should not be drinking alcohol.    There is a one-page handout that was created by Benzo.org.UK for World Benzo Day called Problems and Pitfalls. It explains some of the issues of seniors and elderly folk taking benzodiazepine and some options.      The Mayo Clinic has a list of medications that can cause some concerns in older adults.   The non-profit Benzo Info has a page on the medication called Impact on the Older Adult Population   University of Alabama at Birmingham has a report on More than a million older Americans take benzodiazepines long-term. Here is why doctors want them to stop, and how a UAB psychiatrist approaches the conversation.   Emergency Resources The Trevor Project: Provides crisis support specifically for LGBTQ+ youth through phone (1-866-488-7386), text (START to 678-678), and online chat. Available 24/7. They also provide peer support and community.    Veterans Crisis Line: Call 988 and press 1, text 838255, or chat online. There are phone lines for those serving overseas. Visit the website to find the current status of the Veteran line and international calling options.    National Crisis Text Line: Text HOME to 741741 for free, confidential support 24/7. This service operates independently of the 988 service. Users can use text, chat or WhatsApp as a means of contact.   Disclaimer:  Links to other sites are provided for information purposes only and do not constitute endorsements.  Always seek the advice of a qualified health provider with questions you may have regarding a medical or mental health disorder. This blog and podcast is intended for informational and educational purposes only. Nothing in this program is intended to be a substitute for professional psychological, psychiatric or medical advice, diagnosis, or treatment.  

Recorded live from the American Orthopaedic Society for Sports Medicine (AOSSM) Annual Meeting in Seattle, Dr. Aaron Krych joins Drs. Catherine Logan and Ashley Bassett for an in-depth discussion on the rapidly evolving field of cartilage restoration. The conversation explores how treatment has shifted from simply filling cartilage defects to restoring the entire knee joint through comprehensive patient evaluation, biologic innovations, and advanced surgical techniques.The Evolution of Cartilage RestorationWhy focal cartilage defects should be viewed as a "whole joint disease"Moving beyond isolated microfractureThe growing importance of correcting alignment, instability, and meniscal deficiencyEarlier intervention in young athletic patients to preserve long-term joint healthUnderstanding Natural HistoryWhy untreated cartilage defects can enlarge over timeRisk factors for lesion progression and development of secondary cartilage injuriesCounseling patients on long-term consequences and timing of interventionModern Treatment AlgorithmsWhy strict size-based algorithms are becoming less relevantPatient-specific factors influencing procedure selection:AgeActivity levelDefect size and locationSubchondral bone involvementPrevious surgeryOverall joint healthDiagnostic EvaluationThe expanding role of advanced MRIWhen diagnostic arthroscopy remains essentialEmerging applications of nano-arthroscopy for:Preoperative lesion evaluationAssessment of graft incorporationEvaluation of persistent postoperative symptomsSingle-Stage Cartilage Restoration TechniquesAutoCartSingle-stage autologous cartilage restorationSurgical technique pearlsCartilage harvest using GraftNet technologyPRP/BMAC augmentationTechnical considerations for successful implantationOsteochondral OptionsWhen bone involvement changes the treatment strategyIndications for:Osteochondral Autograft Transfer (OATS)Fresh Osteochondral Allograft TransplantationChoosing between autograft and allograft techniquesAlignment MattersWhy cartilage restoration cannot succeed in an overloaded compartmentIndications for combining osteotomy with cartilage restorationMedial high tibial osteotomy (HTO)Distal femoral osteotomy (DFO)Benefits of patient-specific instrumentation for osteotomy planning and executionLessons LearnedDr. Krych shares valuable experience on why successful cartilage restoration depends on more than the graft itself.Key factors influencing outcomes include:Proper patient selectionMechanical alignmentKnee stabilityMeniscal integrityPatient commitment to rehabilitationKey TakeawaysCartilage restoration has evolved from treating isolated defects to preserving the entire joint.Modern decision-making is individualized rather than based solely on defect size.Addressing alignment, instability, and meniscal deficiency is often just as important as restoring cartilage.Biologic augmentation and single-stage procedures continue to expand treatment options.Successful outcomes rely on appropriate patient selection and meticulous surgical technique.Featured GuestDr. Aaron Krych is an orthopedic sports medicine surgeon at Mayo Clinic specializing in cartilage restoration, complex knee preservation, ligament reconstruction, and sports-related injuries. His clinical expertise and research have helped shape many of today's modern cartilage restoration strategies.Subscribe to The Sports Docs Podcast for conversations with leaders in orthopedic sports medicine, surgery, injury prevention, rehabilitation, and athlete performance.www.cloganmd.comhttps://orthopedicnj.com/physicians/ashley-bassett

In this episode of What's Up, Doc? on the Eye Believe Podcast, we sit down with Dr. Lauren A. Dalvin, ocular oncologist and ophthalmologist at Mayo Clinic, for a conversation that goes beyond medicine. Dr. Dalvin shares the journey that led her to a career in ophthalmology and ocular oncology, the mentors and experiences that shaped her path, and her passion for caring for patients facing rare eye cancers. We also discuss her approach to patient care, her commitment to advancing research, and what continues to inspire her each day. But this series is about more than professional accomplishments. Get to know Dr. Dalvin on a personal level as she reflects on the experiences that have influenced her life, the values that guide her work, and what it's like to balance the challenges and rewards of being both a physician and a researcher. Through personal stories and candid conversation, you'll discover the person behind the white coat. Whether you're a patient, caregiver, advocate, or healthcare professional, this episode offers an opportunity to connect with one of the dedicated physicians helping shape the future of ocular oncology. Learn more about A Cure In Sight: https://acureinsight.org Thank you to our sponsors for making this possible! Ideaya Biosciences Delcath Systems Aura Biosciences Castle Biosciences Immunocore Natera Rare Cancer. Resilient Hope. Revolutionary Research. #OcularMelanoma #EyeBelievePodcast #WhatsUpDoc #LaurenDalvin #MayoClinic #OcularOncology #EyeCancer #RareCancer #ACureInSight

Like tens of millions of people, Stephen Dubner thought he had a penicillin allergy. Like the vast majority, he didn't. This misdiagnosis costs billions of dollars and causes serious health problems, so why hasn't it been fixed? We find out in this update of a 2025 episode.   SOURCES: Kimberly Blumenthal, allergist-immunologist and researcher at the Mayo Clinic. Theresa MacPhail, associate professor of science and technology studies at Stevens Institute of Technology. Thomas Platts-Mills, professor of medicine at the University of Virginia. Elena Resnick, allergist and immunologist at Mount Sinai Hospital.   RESOURCES: Allergic: Our Irritated Bodies in a Changing World, by Theresa MacPhail (2023). "Evaluation and Management of Penicillin Allergy: A Review," by Erica S. Shenoy, Eric Macy, and Theresa Rowe (JAMA, 2019). "The Allergy Epidemics: 1870–2010," by Thomas Platts-Mills (The Journal of Allergy and Clinical Immunology, 2016). "Randomized Trial of Peanut Consumption in Infants at Risk for Peanut Allergy," by George Du Toit, Graham Roberts, et al. (The New England Journal of Medicine, 2015).   EXTRAS: "The Freakonomics Radio Guide to Getting Better," series by Freakonomics Radio (2026). "Doctors Know They Prescribe Too Many Antibiotics. Why Don't They Stop?" by Freakonomics, M.D. (2022). Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Send Zorba a message!Zorba gives an update on the new Alzheimer's blood test developments from the Mayo Clinic and other institutions. And he poses the question: Would you want to know?Support the showProduction, edit, and music by Karl ChristensonSend your question to Dr. Zorba (he loves to help!):Phone: 608-492-9292 (call anytime)Email: askdoctorzorba@gmail.comWeb: www.doctorzorba.orgStay well!

In today's episode, we welcome back Ariel Garten, co-founder of Muse. Ariel is a neuroscientist and former psychotherapist whose brain-sensing technology is used by NASA, the Mayo Clinic, and hundreds of thousands of everyday meditators worldwide.In this conversation, we discuss why meditation feels so hard to stick with, what's actually happening in your brain during those first few weeks of practice, and how to teach even young kids to self-regulate with their breath. We also get into why silence can feel so uncomfortable, whether you can trust your own thoughts, and Ariel's take on using meditation to sit with physical pain rather than fight it.Want to try Muse? It's a headband that reads your brain activity in real time while you meditate, so instead of guessing whether you're doing it right, you get instant feedback that guides you back to focus. Get 15% off Muse at https://choosemuse.com/tadb0:00 – The Problem With Meditation3:07 – What Meditation Does To Your Brain5:23 – Muse vs Meditating Alone8:09 – Teaching Kids To Meditate13:10 – The Fear Of Silence16:15 – Does Location Matter?17:47 – Can You Trust Your Thoughts?20:42 – Talking Back To Your Inner Critic23:05 – Sitting Still vs Walking Meditation26:20 – Meditation In A Crisis28:21 – Is Pain Good Or Bad?36:28 – How Muse Improves Your SleepWant to try Muse? It's a headband that reads your brain activity in real time while you meditate, so instead of guessing whether you're doing it right, you get instant feedback that guides you back to focus. Get 15% off Muse at https://choosemuse.com/tadb

Send Zorba a message!Zorba gives an update on the new Alzheimer's blood test developments from the Mayo Clinic and other institutions. And he poses the question: Would you want to know?Support the showProduction, edit, and music by Karl ChristensonSend your question to Dr. Zorba (he loves to help!):Phone: 608-492-9292 (call anytime)Email: askdoctorzorba@gmail.comWeb: www.doctorzorba.orgStay well!

For years, health systems have focused on building a strong digital front door. But what happens when patients begin their healthcare journey somewhere else entirely?In this episode of The All Access Pass Podcast, Elizabeth Woodcock sits down with Jordan Moore, MBA, Division Chair of the Enterprise Office of Access Management at Mayo Clinic, to explore how artificial intelligence is changing the way patients search for care, choose providers, and navigate the healthcare system.As more consumers turn to AI tools for guidance, health systems face a new challenge: ensuring they remain visible, accessible, and ready to meet patients wherever they begin their search. Jordan shares how Mayo Clinic is preparing for this shift—from rethinking decision trees and demand forecasting to exploring new approaches to patient-provider matching and capacity management.Together, they discuss what access leaders need to do now to prepare for a future where the patient journey starts before a website visit, phone call, or portal login.If you work in patient access, digital strategy, or ambulatory operations, this conversation offers practical insights into the technologies, expectations, and opportunities shaping the future of healthcare access.

What if the milk you are drinking could help fight cancer? In this episode of Tomorrow's Cure, we explore cholangiocarcinoma and a surprising new approach to targeting it using milk‑derived nanoparticles and precision aptamer‑based delivery. Host Lindsey Seavert is joined by surgical oncologist Dr. Rory Smoot and long‑term survivor and advocate Melinda Bachini to unpack why this cancer is so challenging, what symptoms and treatment paths patients typically face, and how emerging gene‑delivery platforms and AI‑driven discovery are opening new possibilities when standard therapies fall short. Through Melinda's 16‑year survivorship story and Dr. Smoot's lab work that literally starts with skim milk from the Mayo Clinic cafeteria, listeners hear how “chemical antibodies” called aptamers can act as molecular keys to deliver therapy directly to cholangiocarcinoma cells, and how computational tools are accelerating the search for new targets. Together, they discuss the emotional and practical realities of living at the edge of what medicine can do today, the expanding landscape of clinical trials, and why innovation in this rare cancer may ripple out to colon, lung and other hard‑to‑treat tumors. How to listen and stay connected: Subscribe to Tomorrow's Cure on your favorite podcast app and follow the show so you never miss an episode. Get the latest health information from Mayo Clinic's experts—subscribe to Mayo Clinic's newsletter for free today: https://mayocl.in/3EcNPNc Connect with Mayo Clinic: Like Mayo Clinic on Facebook: https://www.facebook.com/mayoclinic/ Follow Mayo Clinic on Instagram: https://www.instagram.com/mayoclinic/ Follow Mayo Clinic on X (formerly Twitter): https://x.com/MayoClinic Follow Mayo Clinic on Threads: https://www.threads.net/@mayoclinic

Host: Darryl S. Chutka, M.D.  Guest: Dawn Davis, M.D.  Acne and rosacea are two very common skin conditions seen in primary care, yet at times both the diagnosis and management can be challenging. While acne most commonly develops in adolescence, it can present in adulthood. Rosacea is often misdiagnosed or at times completely unrecognized. What are the common presenting symptoms of these two conditions? What are the treatment options? What are the latest advances in management and when should a primary care clinician consider referral to dermatology? These are questions I'll be asking my guest, Dr. Dawn Davis, Chair of Clinical and Pediatric Dermatology at the Mayo Clinic, as we discuss “Acne and Rosacea”.   Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 

Rita Khan is a board member and advisor for a variety of organizations including a global consulting firm, a marketing agency, an internationally recognized Art Center. She was recently the Chief Consumer Officer at Optum, a UnitedHeath Group company that provides technology services, pharmacy-care services and various direct healthcare services. Rita has also served as Chief Digital Officer for the Mayo Clinic and has worked extensively as an executive in consumer retail, healthcare and digital services.  In this episode Rita shares her journey leading digital transformation in retail and healthcare. She shares her insights on managing teams through transitions and how AI is impacting healthcare. Rita also shares how she is transitioning to a portfolio career - what that looks like and how she has prepared and through about it.In The Lead is a monthly series on Product Rising sharing thought provoking conversations with a wide range of industry leaders hosted by Carmen Palmer, CEO of Women In Product. 00:00 Welcome and Intro01:31 Retail Roots to Product04:26 Early Product Pioneers06:44 Jump to Healthcare09:06 Mayo Digital Officer Role12:22 Culture and Change Agent15:53 Measuring Outcomes in Health18:15 Shipping Fast in Regulated21:29 AI in Healthcare Today24:32 Agentic Future for Patients26:13 Trust and Transparency26:52 Leading Through AI Change29:35 Building a Portfolio Career32:49 Designing the Flywheel35:41 Whole Self and Networks39:11 Burnout and Boundaries41:54 Empathy in High Pressure44:25 Women Shaping AI Future46:48 Courage and Finding Voice48:56 Sponsors and Mentors50:08 Healthcare Automation Vision51:21 Final Charge to Lean In✨Where to find Rita:On LinkedIn

Pulsed Field Ablation for Atrial Fibrillation with Left Atrial Appendage Occlusion   Guest: Ammar Killu, M.B.B.S. Host: Anthony Kashou, M.D.   In this episode of Interviews with the Expert: ECG Making Waves, host Dr. Anthony Kashou is joined by Dr. Ammar Killu to discuss the evolving role of combining pulsed field ablation (PFA) with left atrial appendage occlusion (LAAO) for patients with atrial fibrillation. Together, they explore the rationale for a combined approach, the potential advantages of PFA over conventional thermal ablation, and key procedural considerations for performing both interventions safely and effectively in a single session.   Topics Discussed: Why consider combining pulsed field ablation and left atrial appendage occlusion in the same AF patient? What does PFA add compared with conventional thermal ablation when planning a combined ablation–LAAO strategy? What are the procedural caveats when PFA and LAAO are done concomitantly?   Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode.   Podcast episode transcript found here.   Recorded on: 26-June-2026  

The "Community Meets Clinic" podcast series introduces clinicians and healthcare personnel specializing in rare neuroimmune disorders. In this episode, Krissy Dilger of SRNA spoke with Dr. Ayşe Altıntaş, Professor of Neurology at Koç University School of Medicine in Istanbul, Turkey, which has been designated as a Center of Excellence in Rare Neuroimmune Disorders. Dr. Altıntaş described the unmet needs in rare neuroimmune disorders and noted her role on an international panel developing updated NMOSD diagnostic criteria [00:03:40]. She outlined current research on mechanisms of optic neuritis, pregnancy complications and aquaporin-4 antibodies, and developing accessible biomarkers beyond CSF with a future goal of remote monitoring [00:06:01]. Dr. Altıntaş also explained Koç University's multidisciplinary demyelinating disease center model, emphasizing coordinated consultations, advanced MRI capabilities, shared decision-making, and the value of specialized centers, while expressing hope due to rapid advances in biomarkers and targeted therapies [00:11:43]. You can view the medical profile of Dr. Ayşe Altıntaş here:https://www.kuh.ku.edu.tr/doctors/ayse-altintasAyşe Altıntaş, MD is a professor of neurology at Koç University School of Medicine in Istanbul, Türkiye. She graduated from Ege University Faculty of Medicine in 1986 and completed her neurology residency there in 1992. She received early training in neuroimmunology as a fellow at Mayo Clinic under Prof. Moses Rodriguez and later continued her research at Mayo Clinic with Prof. Claudia Lucchinetti and Prof. Brian Weinshenker, focusing on the animal model, immunopathology, and imaging correlates of multiple sclerosis.Prof. Altıntaş served at Istanbul University Cerrahpaşa School of Medicine for 23 years before joining Koç University in 2018, where she established a neuroimmunology laboratory and continues to lead clinical and translational research. Her work focuses on multiple sclerosis, neuromyelitis optica spectrum disorders (NMOSD) and MOG antibody-associated diseases (MOGAD), with an emphasis on biomarkers and disease mechanisms. She is actively involved in international organizations, including BioMS-eu, The MOG Project, Siegel Rare Neuroimmune Association (SRNA), MEDEN, the MSBase Scientific Leadership Group, and the Guthy-Jackson Charitable Foundation International Scientific Consortium.00:00 Welcome and Guest Intro01:39 Why Neurology03:40 Choosing Rare Disorders06:01 Current Research Projects11:43 Clinic Team and Workflow15:48 Advanced Imaging and Coordination17:20 Self Care and Balance20:20 Advice for New Patients22:17 Hope for the Future24:34 Closing

Recorded live from BIO 2026 in San Diego, Gil sits down with Dr. Steven Lester, cardiologist, Professor of Medicine, and Medical Director of Mayo Clinic's Discovery Oasis, to unpack one of healthcare's boldest innovation bets. Lester explains how 120 acres on Mayo's Phoenix campus are becoming a biotechnology innovation hub designed to pull commercializable know-how out of one of medicine's most storied institutions — and why most healthcare innovation fails not at the idea stage, but at the friction between pilot and scale. The conversation ranges from the "great unscaling" of medicine to Lester's personal stewardship philosophy, forged through an unlikely cross-border citizenship story.

Republican candidates for governor are telling voters they'll reduce Minnesota's budget and taxes if they're elected. Democrats called on Republicans to more clearly spell out what they'd seek to cut.A federal lawsuit alleges that the medical giant Mayo Clinic has been cutting corners as it incorporates artificial intelligence into its research and patient care.Deere & Company, a farm equipment manufacturer, reached a settlement with the Federal Trade Commission and five states, including Minnesota.

In this episode, I welcome back Dr. Chrisandra Shufelt, one of the world's leading researchers in Functional Hypothalamic Amenorrhea, to discuss exciting new findings from the largest HA studies to date.For years, women with missing periods have been told to simply "go on birth control" or have struggled to find answers from healthcare providers. Now, new research is beginning to uncover what HA is really doing to the body—and why recovery matters far beyond fertility.Together, we discuss:• The largest Functional Hypothalamic Amenorrhea studies to date• Early findings on heart and cardiovascular health• Why stress plays a significant role in recovery• What researchers discovered about eating patterns in women with HA• Bone health, inflammation, and long-term health risks• The most common symptoms women report beyond a missing period• Why HA remains dramatically under-researched• How you can contribute to future research through the international HA registryWhether you're currently recovering from HA, supporting someone who is, or you're a healthcare professional wanting the latest evidence, this conversation provides practical insights backed by emerging science.The more we understand Functional Hypothalamic Amenorrhea, the better we can support women in recovering not only their periods—but their long-term health.Apply for Recipe for a Period coaching w/Cynthia: https://www.periodnutritionist.com/applyforcoachingNew to HA? Discover the truth about HA:  click the link to download Cynthia's fact sheet that debunks common myths and misinformation! Trying +3 months to get your period back? Click here to download the Safety WorksheetYouTube: https://www.youtube.com/@theperiodnutritionist Instagram: www.instagram.com/period.nutritionistMayo Clinic Registry LinkResources Mentioned: Breaking New Ground in HA Research: Dr. Shufelt on the REVEAL Registry & Period RecoveryDr. Shufelt is Professor and Chair of the Division of General Internal Medicine at Mayo Clinic in Jacksonville, Florida, and Associate Director of Women's Health Research Center at Mayo Clinic Enterprise. She is a women's health internist with fellowship training in vascular biology and women's health and a certified menopause practitioner. She has several National and International leadership roles in the American College of Physicians, the European Menopause and Andropause Society and the North American Menopause Society where she is the immediate past-President of the Society and on the board of trustees. Dr. Shufelt has over 200 publications in the area of women's health and has also co-authored several scientific position statements on menopause and hormone therapy. Her NIH-funded research focuses on young women with hypothalamic amenorrhea evaluating the impact on immune and vascular health.

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., president and CEO of Mayo Clinic Laboratories, to discuss recent artificial intelligence (AI) initiatives in the news. She then welcomes Jane Hermansen, manager of Mayo Clinic Laboratories' Outreach Program, to discuss the value of outreach programs in strengthening laboratories and supporting broader healthcare systems.AI's potential and limitations (00:01): Learn what's next and the challenges that remain as Drs. Pritt and Morice discuss recent stories about AI in healthcare. Value of outreach (07:30): Discover how laboratory outreach programs support their organizations, delivering benefits that range from improved patient care to lower testing costs and growth across health system service lines.Getting the most from outreach (15:54): Learn the three most important things lab leaders can do to get the greatest value from their outreach program. The future of outreach (17:53): Get insights on how outreach may evolve in the coming years as healthcare changes.ResourcesFortune: A decade after the ‘Godfather of AI' said radiologists are obsolete, salaries are $571K and growing“Answers From the Lab” podcast: Digital Advances: What's Next for Clinical Diagnostics?Personalized pathways through digital diagnostics: A Q&A with Chris Garcia, M.D. Outreach & Business SolutionsOwn your lab: Hospital-owned labs generate long-term financial and clinical valueLeveraging the Laboratory Conference

AI is quickly becoming one of the biggest professional advantages of our time. It can help people save time, organize their ideas, create content faster, communicate more clearly, and get more done with fewer resources. But if women are slower to adopt these tools, the gap will not just be technical. It could become economic, professional, and generational. Women are already expected to carry a lot. They are building businesses, managing households, leading teams, caring for families, serving clients, and trying to stay visible in a world that rewards speed and consistency. For many women, the issue is not a lack of talent or ambition. It is capacity. That is why AI matters. Used well, AI can become a powerful support system. It can help women turn ideas into action faster, repurpose their expertise into content, streamline repetitive work, and create more room for strategy, creativity, and leadership. In this episode, you'll learn about the gender gap in AI adoption and why women cannot afford to treat AI as optional.   Guest Bio Erica Hanna, the Co-Founder of Camcorder AI, a generative ai video marketing startup based out of New York City, and Owner of Puke Rainbows Creative, a full-service video production company based in Minneapolis, is always looking towards the future. A 6-time Emmy Award Winner, her directing and producing talents have resulted in projects for clients including: Prince, Ellen DeGeneres, CBS, Mayo Clinic, and Black Voters Matter. She has also been awarded "Twin Cities Top Twitter Personality" three different times. Go to camcorder.ai to sign up for free and email erica@camcorder.ai for a video walkthrough.     About Your Host Marki Lemons Ryhal is a ​​Licensed Managing Broker, REALTOR®, and avid volunteer.  She is a dynamic keynote speaker and workshop facilitator, both on-site and virtual; she's the go-to expert for artificial Intelligence, entrepreneurship, and social media in real estate. Marki Lemons Ryhal is dedicated to all things real estate, and with 25+ years of marketing experience, Marki has taught over 250,000 REALTORS® how to earn up to a 2682% return on their marketing dollars. Marki's expertise has been featured in Forbes, the Washington Post, Homes.com, and REALTOR® Magazine.   Subscribe, Rate & Review Check out this episode on our website, Apple Podcasts, or Spotify, and don't forget to leave a review if you like what you heard. Your review feeds the algorithm, so our show reaches more people. Thank you!     

Host: Darryl S. Chutka, M.D.  Guests: Jake Eide, M.D. & Rijul Kshirsager, M.D.  Skull base tumors are not commonly seen in a primary care practice, yet it's important for us to recognize them when they do present. These tumors can be either benign or malignant, however because of their proximity to important structures in the brain, even benign tumors can cause serious complications. Their presentation can be subtle, and they are frequently mistaken for other more commonly seen health problems. Which presenting symptoms should give us concern? What are some common physical exam findings associated with these tumors, and what's the best initial imaging study to order? These are some of the questions I'll be asking my guests, Dr. Jake Eide and Dr. Rijul Kshirsagar, both surgeons in the Department of Otorhinolaryngology at the Mayo Clinic as we tackle “Skull Base Tumors.”  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 

Most founders obsess over their product. The real skill is knowing which problem to fall in love with instead.In this entrepreneur interview, Nyamitse-Calvin Mihanda — founder of Vital Audio and a Techstars and Fuel Accelerator alum — shares how his company extracts heart rate, respiratory rate, and blood pressure from ordinary conversation, why he walked away from a "perfect" product mindset, and how his path from hospital billing collector to healthcare founder shaped the way he builds teams today.Whether you're building your first startup or trying to close the access-to-care gap in your own community, this conversation will change how you think about resilience, timing, and what it actually takes to launch.What you'll learn:How signal processing and machine learning pull vital signs straight from a voice recordingWhy clinical partnerships with NYU Langone and Mayo Clinic came before scale, not afterThe "fall in love with the problem, not the product" principle that keeps founders from chasing dead endsWhy soft skills — not technical skills — are the hardest thing to teach a teamHow rural and underserved communities stand to benefit most from voice-based vital tracking⏱️ Chapters:0:53 Welcome to the Startup Junkies Podcast1:16 How Vital Audio Reads Vitals From Your Voice2:21 The Science Behind Extracting Vitals From Speech3:09 Landing Clinical Partners: NYU Langone, Mayo Clinic & More4:16 From Hospital Billing to Healthcare Entrepreneur6:13 Techstars vs. The Fuel Accelerator: What's Different8:55 An Immigrant's Resilience: Lessons From Tanzania to NYC11:03 Why Soft Skills Matter More Than Technical Skills12:25 The Best Advice: Fall In Love With The Problem14:18 Overcoming Fear When You Start a Company14:47 What Nyamitse-Calvin Mihanda Loves About the Arkansas Ecosystem17:06 Closing the Rural Healthcare Access Gap19:47 Where to Find Nyamitse-Calvin & Vital Audio

The president of the American Medical Association became the patient after being diagnosed with a large brain tumor. Dr. Bobby Mukkamala, immediate past president of the AMA, joins Chuck Carroll on The Exam Room Podcast for a powerful and deeply personal conversation about how his diagnosis changed the way he sees health care, medicine, prevention, access, and the patient experience. Dr. Mukkamala opens up about being diagnosed with a grade 2 astrocytoma, the shock of seeing an eight-centimeter brain tumor on his scan, and what it felt like to suddenly experience the health care system from the other side of the exam room. He also reflects on the extraordinary care he received at Mayo Clinic and the difficult reality that most people do not have access to that same level of care. The conversation also explores the crushing cost of medication, including a new treatment that can cost nearly $900 per day, and why medical bills remain such a devastating burden for so many families. Chuck and Dr. Mukkamala also discuss lifestyle medicine, plant-based nutrition, the future of health care, dietary guidelines, health equity, and why progress can still be powerful even when perfection is not realistic. This interview was recorded at the Lotus Health Foundation Symposium in Rochester, Minnesota, just days before Chuck's major surgery at Mayo Clinic. At the time of the conversation, Dr. Mukkamala was still serving as president of the American Medical Association. Topics discussed include: What happens when a doctor becomes the patient Brain tumor diagnosis and recovery The emotional impact of serious illness Health care access and inequality The high cost of prescription medication Mayo Clinic and world-class care Lifestyle medicine and disease prevention Plant-based nutrition and health The role of doctors in improving public health Why progress over perfection matters Exam Roomies of the Week Carol Kimsey MJ Donahue Tomi Gail Lemmen Make a gift to support The Exam Room Podcast and the life-changing work of the Physicians Committee: PCRM.org/SupportExamRoom

Dr. Deb Muth 0:05What if your immune system isn’t broken, it’s just confused? What if chronic Lyme, the autoimmune condition, the food sensitivities, the exhaustion that never lifts what if those aren’t separate problems but one problem? A misfiring immune system that nobody taught how to stand down. Today’s guest has spent over 15 years doing exactly that, retraining the immune system from the inside out with a therapy so precise, so safe, and so effective that it has changed the lives of thousands of people who’d been written off by conventional medicine. Stay with me. This one changes everything.Welcome back to Let’s Talk Wellness Now, the show where we pull back the curtain on chronic illness, challenge outdated medical thinking, and hand you the real tools to heal from the inside out. I’m Dr. Deb, integrative and functional medicine practitioner, medical detective, and your straight-talking guide through the world of root cause medicine. Today, we’re going to dive deep into the immune system, specifically something called low-dose immunotherapy or LDI, and also into some hormones, chronic fatigue, and what it actually looks like to treat the cause instead of suppressing the symptoms. If you or someone you love has been told there’s nothing more we can do, this episode was made for you. Grab your cup of coffee, Settle in and let’s get to work. Now, before we bring in today’s guest, a quick word from our sponsor, and then we are diving straight in. I promise. Did you know sweating can literally heal your cells? Infrared saunas don’t just relax you, they detox your body, balance hormones, and boost mitochondrial energy. I’m obsessed with my HealthTech Sauna, and right now you can save $500 with my code at healthtechhealth.com/dr-muth-req-25.I want to start you with a story because this is one I’ve heard hundreds of times in my own practice, and I’m guessing you’ve either lived it or know someone who has. She’s 42. She’s been sick for years. Fatigue that doesn’t lift with sleep, joint pain that migrates, brain fog so thick she can’t finish a sentence, and a gut that seems to react to everything she eats. She’s been to her GP, rheumatologist, gastroenterologist, maybe even an immunologist, and every single lab comes back within quote unquote normal limits. She’s handed a prescription for something to manage the symptoms and sent home. Maybe she’s been told it’s anxiety. Maybe she’s been told it’s aging, or maybe and this one always breaks my heart she’s told it’s all in her head. That woman is not imagining it. She is not anxious and she’s not aging poorly. Her immune system has lost its ability to tolerate things it’s supposed to tolerate, and no one has offered her the therapy that could actually fix that. And what we’re talking about today with my guest has been practicing integrative medicine for over 15 years. Ty Vincent holds a medical degree from the University of Washington. He completed his family medicine residency in Anchorage, Alaska, and since has built one of the most impressive clinical repertoires I’ve seen anywhere in this field: acupuncture, Chinese medicine, environmental medicine, bioidentical hormones, hyperbaric medicine, chelation, regenerative peptide therapy, psychedelic-assisted therapy, and nutritional medicine.He lives and practices on the Big Island of Hawaii. He is married has 9 children. Oh my gosh, 9! And he has personally navigated type 1 diabetes, which, as you’ll hear, is not separate from his mission. It actually is his mission. And most importantly, he is a world authority on low-dose immunotherapy, a therapy he pioneered in 2008 and since has trained over 200 providers globally and changed the course of chronic illness care as we know it. I have had the pleasure of learning from Dr. Ty Vincent. I have had pleasure of taking his low-dose immunotherapy course when he first started back in like 2008 or 2009. I remember doing it back then and learning more about it in 2011. And this is going to be a great conversation for us. So one quick ask that I have for you guys, if this sounds like something that you want to learn more about and you’ve listened to some of our shows, please share like, subscribe. It means a lot. It helps us grow our channel. It helps us continue to provide for you different topics, different speakers, and really give you what it is that you’re looking for.So without further ado, I’d like to introduce you to Dr. Ty Vincent. All right, so Dr. Ty Vincent, this is gonna be a great conversation. We were just chatting before we went live of my training with you guys way back in like 2015, and I’m excited to hear all the new things that you’ve got going on. But introduce yourself to the audience. Tell us a little bit about you, how you got involved in this, uh, where you’re at, all that good stuff. Tyvincent 5:29Okay. I, uh, it’s a long story, but some of the highlights, I guess I was born in Alaska in the early ’70s and grew up there kind of wandering around in the woods with my dogs with no one around all day long. It was amazing. You don’t get kids don’t get that experience anymore. So you kind of learn to be an independent thinker, I think, you know, because latchkey kid, parents weren’t home till 6 and you’re on your own from early. Dr. Deb Muth 5:49That was a great time, wasn’t it? Yeah. Tyvincent 5:51I mean, I have, I have 9 children now and none of them grew up like me. And despite my effort, I mean, I’d have to basically like helicopter them out in the woods and drop them off for a few hours for them to understand what independent kids today are so dependent and parents are so helicopter that, uh, it’s changed. Anyway, I, I grew up just really liking science and really loving science, a huge nerd. And, um, and, uh, when I went into college, when I wanted to be a marine biologist and I thought that that was my passion of the ocean wildlife and all that, and then halfway through college, personal Couple things made me change my mind. It was a girl, you know, the usual. And I decided to go to school in Anchorage instead of going I was, I was transferring to Hawaii and I was going to study marine biology. And then, uh, my girlfriend moved back to Alaska where we were from. And I decided to do that instead. And then they didn’t have a marine science program.So I decided I’ll just get a biology degree and go to medical school. I’m a smart guy. I can do that, but I had no awareness of medicine. I really didn’t have any, you know, the passion some people have to be a healer and to go help people wasn’t part of the calculus at all for me. I was kind of an Asperger’s kid, so that really wasn’t the way I thought, honestly. And then I went into medicine and I was really interested in the science, the biology, the biochemistry, all the stuff, the physiology. And before I started medical school, I was reading some Andrew Weil’s books and I was, I decided to get a book on nutritional biochemistry because I naively thought that’s what they were going to teach me, right? This is how you make people healthy. You figure out how it works and you give them the things that make their body work right. Yeah. And we all know that that’s. Not been true for over 100 years now since the Flexner Report. And, you know, the rich people steered the government towards pharmaceuticals. Dr. Deb Muth 7:26Yeah. Tyvincent 7:26But that was my interest. And when I went through the first 2 years of medical school, I just really devoured all of the basic science stuff. And that was what I thought was the most important. And I honestly mastered all that. I scored in the top 1% in the country on all the exams and everything. And it was the top, in the top of my class at the University of Washington. And then you start doing clinical medical training and you discover that they don’t use any of that knowledge anymore, really, unless it pertains directly to pharmaceuticals, and that pharmaceutical research is extremely narrow and reductionist, and they only want to try to prove one little effect, and it doesn’t translate to real health. So as I got into clinical work and started residency, you know, by the third year of residency, I was like, they didn’t really teach me how to help people with chronic illness. You know, I was, I went to family medicine residency, so I was delivering babies.I was assisting with surgeries. I was in the ER. I was doing colonoscopies. I actually did colonoscopies in practice after residency, which family Doctors almost never get to do, but I’m a small town in Alaska. So I managed my own ICU patients and did everything, literally circumcisions in the office. And you’re dealing with like hospice and end of life care, just both ends, right? Pregnancy to death. And so I’d realized that if I really wanted to do the job well, which was my goal, I needed to learn other things. And in my, in my third year of residency, I actually did the extra, like, like additional training in medical acupuncture that was put on by the Helms Medical Institute then with Joseph Helms.And that was great. And I had to learn Chinese medical theory and I learned, I did the extra module on Chinese herbal medicine. And it was wonderful because I had to open my mind to a completely different way to evaluate people and illness. And I thought, okay, well then there’s got to be more. And as I went, I just became this voracious consumer of broad medical knowledge, not conventional medicine. You notice how a lot of the conventional people call it traditional medicine? Dr. Deb Muth 9:07Yes. Tyvincent 9:07Which annoys the crap out of me because there’s nothing traditional about something that’s been around for 100 years. I mean, you need time, you need like an epoch to say something’s traditional. But they’re like, no, I’m like, and then we were considered alternative medicine minded and everything like, oh, well, Well, it’s an alternative to real medicine. The vernacular in our culture really dictates thinking, unfortunately. I went on to learn functional medicine. So like 2005, I did the acupuncture training. 2006, I found the IFM and I read their entire textbook in a few months. And I went to the trainings. I was like, okay, now I know what you guys have to teach me. And then I found a bioidentical hormone therapy training course that was like Jonathan Wright and Terry Hertog. Dr. Deb Muth 9:46Terry Hertog, yes. My favorite guys. Tyvincent 9:49They were great. Dr. Deb Muth 9:50Pioneers, right? Tyvincent 9:51Yeah, exactly. And, you know, I learned what their opinions were and all that. And then you don’t really learn how to use a tool or you don’t get really get facile with something until you are using it and you’re applying it to your patients. And I went beyond that. I learned all kinds of IV nutrition. I learned chelation therapy. I joined the Environmental Medicine Academy and I learned how to do various forms of immunotherapy, eventually leading to learning LDA, low dose allergy therapy, through them in 2008. And for those of you listeners who don’t know about low-dose allergy therapy, when you learn about it, basically it’s like homeopathic dilutions of antigens.But instead of single antigens, like if you go to that regular allergist, they’ll just prick test you, blood test you, whatever, and say, oh, you react to mold, you react to chicken, you react to your husband’s whatever. They don’t test for that. I sometimes do. And they’re very narrow-minded about it. And it’s like you just give the antigens that the person tested for and you’re always missing something. With LDA, you get these huge broad mixtures of antigens, like for foods, it’s just hundreds of foods compiled into one for environmental allergens. And the reason you can get away with it is that the dilution factor is so far out. There’s no physical interaction with the body and you can’t, there’s no risk of inducing allergy, right? Whereas conventional shots might be 1,000 to 1, 100 to 1 dilution. We’re out at like a billion to 1 or further in most of these. And it sounded like nonsense to me, right? Despite all of my training I’d already had and all these things and being open-minded, it still sounded ridiculous. Pointless, right?But at least I was willing to give it a try because I had patients in my clinic, my family medicine clinic in Alaska, that had horrific allergies. Just like kids with eczema from head to toe. They look like they’ve been set on fire. Half their hair wouldn’t grow out of their head. They’re just miserable. They won’t grow. They’re on steroids. And I just thought, if there’s if this has any chance of working for these kids, I’m going to give it a try. Plus, two of my kids at the time had eczema, like persistent eczema that was really annoying. And I kids with eczema is a near and dear thing to me now. I like, I get emotional treating these kids, but, but that’s because it’s miserable for the families. Right. So I took it hard and I started treating my kids and, and, uh, kids in my clinic with LDA and it worked like magic because magic is just science we haven’t figured out yet. Right. We just, you know, some, but it was undeniable that it was working incredibly well. And then I was like, well, what is going on here? How does this work? And you learn the whole history of it. It goes back to the 1950s. I’m like, but, but it’s still so limited. There’s so much more as you start to treat patients with every tool in your toolbox, you run into these walls occasionally where you’re like, okay, everything I’m doing now isn’t working. And this patient has some kind of chronic inflammation, which is a very general term.People go, I have inflammation. Yeah, yeah. What we all do every day, all the time. But they would have these chronic inflammatory disorders that really seem to be immune driven. And then I thought, well, in terms of understanding low-dose allergy therapy, if I can identify what the target antigen really is that’s underlying this patient’s condition, and I can restore tolerance to that, which is basically how LDA works, then you could resolve it. And so I set about experimenting with all kinds of autoimmune disorders. I mean, at the time, LDA and the predecessor therapy called EPD, they had a few bacterial antigens, and we knew that there were connections between like rheumatoid arthritis and the bacterium Proteus. So that was in one. Klebsiella was the target antigen for ankylosing spondylitis. I’m thinking, well then, what about all these other autoimmune disorders? So I started just treating people creatively and trying all kinds of different things. Luckily, I had a contact in Orange County who had a warehouse, like a biomedical sample warehouse, and he was willing to give me antigen mixtures almost anything you could imagine in the biomedical world.The first thing I had him put together was Candida. I found those of us in the medicine space realize that some people have this huge problem with Candida. The conventional medical world thinks, well, yeah, everybody’s got Candida. That’s not a thing unless it’s an infection, blah, blah, blah. But you see these patients that are super ill, persistently ill, and you give them antifungals because you think, okay, well, you have these red rashes and itching and constipation and fatigue and muscle pain, blah, blah, whatever. It sounds like a yeast problem. Some of them, interestingly, if you do stool analysis, they show no yeast on their stool, which is a clue to me with a different thinking process that the reason the yeast isn’t growing in their stool is their immune system must be attacking it and killing it off in the gut, right? Because who doesn’t carry Candida? So the, the tests that run those are the stool company the test the companies that run the stool test, they don’t flag that result as abnormal because, yay, good, you have no yeast. But it’s horribly abnormal, right? Like if you saw somebody with no, no ears, you’re like, that’s not right. And so I thought, well, maybe they’re immunologically hypersensitive Candida. And so I, I was able to purchase a mixture of Candida species. And it occurred to me that I should include Saccharomyces cerevisiae in there because baker’s yeast and brewer’s yeast, people become sensitive to that too.So I made this and some of the patients that I was seeing where I would put them on Diflucan and Nystatin and all their symptoms would just evaporate, right? But you try to stop the medications after a month or whatever, and within 48 to 72 hours, their symptoms are right back. And that was one of the things, another clue to me, like, well, then that’s not an infection. I mean, they’re not taking antibiotics. They’re not eating a ton of sugar. Why would this regrow? And one of my criticisms of our integrative medicine world is we have just as many fairy tales and dogmatic beliefs as the conventional medical world. They’re just more colorful. Dr. Deb Muth 14:59That is true. That is very true. Yeah. Tyvincent 15:01And people were saying, oh, well, it’s because Candida lurks and hides in these nooks and crannies and corners in your body. And I’m like, I’ve done colonoscopies for years. I don’t know what you’re talking about. Like, it’s sparkling clean in there after some Go Lightly or whatever you torture your patient with the day before a colonoscopy. I was like, well, that doesn’t make sense. And they’re like, well, it’s because Candida uses mercury as a weapon to fight off your immune system. I’m like, you’re anthropomorphizing this organism as if it had agency to make tools, right? It doesn’t make sense. So then I came up with this idea to desensitize people to Candida. And it was incredibly effective.These patients, when you find the right dilution, you know, and for those who don’t know, it’s just a couple of drops of water put under your tongue, taken out of a syringe from multiple different dilution steps of the mixture, whether they’re using, right? So these people would respond. Most things I’ve developed, people respond. Somewhere near a trillion to one mathematically. And it was incredible. And I was like, okay, this is something that I’m sure relates to other chronic illness problems. And I started experimenting with I had a couple of patients with inflammatory bowel disease, ulcerative colitis, both of them early on. That was 2009. And I was like, well, they didn’t respond to the yeast mixture. They didn’t respond to the food mixture. And I was like, well, they’re reacting to something.And presumably that something is living in their gut. Right? I now know people react to different bacteria. There’s a ton of different bacteria and other organisms in your stool. So I came up with the crazy idea after seeing Dr. Bill Ray at an environmental medicine meeting talk about what he called autologous vaccines. Dr. Deb Muth 16:29Right? Tyvincent 16:30And I want to be clear, the way a vaccine works is probably the total opposite of how LDA works. It’s not the same thing. You’re restoring tolerance with LDA, LDI, and you’re promoting a robust immune reaction to a target antigen with a vaccine. At least that’s the theory. And now I’m not. It’s true. But Dr. Ray was talking about that and I thought, well, that’s a cool idea. And I went up and I asked him like, how do you do this?How do you make these things? And he kind of gave me like a very brief, you know, brush off. He didn’t know me very well. He’s like, oh, you get these Millipore filters, these little things you put on a syringe and you can dilute something and pass it through into a vial and it’ll be a sterile solution and you can dilute it. I was like, oh, great. So I collected one of my ulcerative colitis patients’ stool who was having at the time like 12 bloody bowel movements per day, every day. He’d seen all the conventional gastroenterologists. He tried the different drugs. They weren’t working. He went to some really special integrative greater clinic in California that primarily dealt with gastrointestinal disorders, and he did everything they wanted him to do, and it also didn’t help.I did discover that he was sensitive to gluten, and when he went off gluten, his, his gut still didn’t improve. So I made this autologous stool, um, LDA I called it then, which now I change it to LDI because LDA is a proprietary term and it’s also very narrow in scope. And I gave him doses and looked like the second dilution maybe that I went through hit. Literally his, his diarrhea and bleeding stopped overnight. And by 3 days he was having completely normal stools and no pain, nothing. And that taught me a couple of things. One, this theory works, right? And two, you know, we talk about the concept of leaky gut in the alternative medicine world, like integrative medicine world, sorry, a lot.And I’m like, yeah, but that’s not a diagnosis. That’s a symptom. You know, you still figure out what’s causing inflammation. And people are like, I just have leaky gut. It’s chronic. And you know, what do you do? And what I found was if you just put the fire out, the house rebuilds itself. Health very quickly. You know, we know that the lining of the gut turns over extremely fast. That’s why it is one of the first things to go when you do chemotherapy. And these people were basically healed to normal within less than a week. Same thing with kids with eczema that had these horrible oozing, weeping skin patches. Dr. Deb Muth 18:25I would. Tyvincent 18:25Or psoriasis even. When I developed some things that would treat psoriasis later on, you, you give this person with just, you know, deforming sort of rashes the right antigen, within 3 to 5 days they have normal looking skin except for maybe residual depigmentation or scarring if but it just blew me away. Dr. Deb Muth 18:42That’s crazy. 3 Days. Tyvincent 18:44The key to solving these problems was to restore immunological tolerance for the thing that it had lost tolerance for. Dr. Deb Muth 18:50Right. Tyvincent 18:50And it just really made me think about everything we were taught about chronic illness and everything we’re taught about the immune system in a very different way. And so since 2009, I’ve developed I’ve continued to develop new mixtures for new things because I run into patients. I can treat so many more things now highly successfully than I could before, but there’s still always the failures. People would ask me over the years, you know, why did you pick up all these skill sets?Like I learned acupuncture and Chinese medicine. I learned bio I became a Reiki master even, because I’m like, well, energy is a thing too. And so I get into the energy medicine world and that also works. And especially if you add it to acupuncture, it’s a great combination. All this stuff. And I would still fail. And I, it occurred to me when people ask me the question, like, I’m driven by failure. I really don’t like it. And I said, uh, and I thought that was how everybody believed, you know what everybody thought, right? But then you when you study our conventional medical colleagues and a lot of our people in the integrative medicine world too, that are doing the same things, the same protocols.And I hate the word protocol because it’s a poor substitute for thinking, right? It’s so that you don’t have to think here, follow this list, but everybody’s so different. So I never developed a protocol for anything to this day. I don’t, that’s not what I do. I was like, despite all of this, their patients aren’t getting better either. And it’s like, well then, you know, just philosophically, which I was a big philosophy student in college too. I thought if, if what you’re doing doesn’t work, do something different, you know, make new mistakes, figure things out. And I just got really creative. And by now I have, my gosh, I have 100 different kinds of antigen mixtures. And to be very honest, half of them have never worked for anything because that’s how it works, right? You got to. Dr. Deb Muth 20:17You’re trying it. Geez. Yeah. Tyvincent 20:19You’ve got to be willing to be wrong if you ever want to be right. One of the things I’ve noticed about humans in general is they’re very unwilling to see when they’re wrong because it’s emotionally painful to let go of something that has maybe been a part of your self-identity or especially like when you get experts in a field and they’re famous for some theory or treatment or whatever they developed, even if evidence shows up later, which it inevitably does, to show that what they’re doing isn’t complete, maybe not wrong, but not complete, there’s huge resistance, right, to the change. Dr. Deb Muth 20:49No one will admit that there’s something that didn’t work initially when they thought it did. Tyvincent 20:54Right. And nobody wants to admit I’ve been doing something wrong or ineffective or less than it could be for 20 years. You know, that’s unsettling. But to me, I’m like, well, isn’t it worse to keep doing it wrong? Right? Dr. Deb Muth 21:06That’s the whole idea. Like, right? We’re supposed to be bettering ourselves. Medicine’s supposed to be adapting and changing, and we don’t. Like, there’s a lot of things that we still do the same way we did in the 1950s and ’60s. Cancer treatment is one of them, right? We don’t really do anything different than we did back then. And when you look at precision medicine, we have all these new tools, but people stay stuck in their way of doing things just because maybe it’s easier, they’re comfortable or whatever. It doesn’t always make it the best interest for the client. Tyvincent 21:36No. And that is the goal we all need to keep in mind. Dr. Deb Muth 21:38Yeah. Tyvincent 21:39What I thought was like the job is to fix the problem the person has. And if the tools you currently have don’t do that, you need to learn something else. Dr. Deb Muth 21:48Yeah. Tyvincent 21:48And eventually I got a little saturated with learning new things. Dr. Deb Muth 21:51I’ve been there. Tyvincent 21:54Turns out there’s a limit. You know, we use the term drinking from the fire hose for everybody who like comes, like conventionally trained doctors who first get into the integrative medicine world. You’re just like, what are you talking about? It’s all so foreign and new. And then you have to use it and realize, okay, there’s, there’s a lot of truth here. But I got to a point where it’s like, I just don’t have the time in my day to use every tool. Like I bought an Indigo machine. I don’t know if you’ve heard of it. So the old EAV technology from Germany long ago, electrodiagnostic things and Then they developed computer programs and software that could analyze 11,000 different frequencies. It’s all energy frequency based. And I bought one of these for like $25,000. I still have it in the case collecting dust because I just didn’t have time to learn how to use the tool. And I was like, all right, I got to just get really, really good at some things and then let my colleagues who are good at other things help people with the things I can’t treat and I’ll tell them where to go. You know, it’s a collective, it’s a team effort. Dr. Deb Muth 22:47Right. It’s got to be a team effort. I’m curious what you’re finding these days with the newfound for mass cell, right? MCAS, everybody’s problem child, and nobody has a good answer. And it’s, it’s an immune reaction, right? It’s not just that I’m allergic to everything situation. Back in the day, 20 years ago, you and I would have called these the chemically sensitive people, and now we at least understand what’s going on. It’s an immune reaction. But I’m curious what you’re finding with LDI and that population of people. Tyvincent 23:19It’s a really good question. I know, I know you’ve had other interviews where people have discussed it philosophically to start the conversation. I really have found over the years that a diagnosis is the least helpful thing you can give your patient. Dr. Deb Muth 23:31Agreed. Tyvincent 23:31But we love labels. We love names. And we, and the problem is when you give something a name that does not reflect what’s actually going on, it just leads everybody’s brain in the wrong direction. And so there’s nothing wrong with these people’s mast cells. And that’s why I’m like, I despise the term mast cell activation disorder, but It is okay that they may be the end of the line releasing histamine and whatever, but a lot of these people have tons of inflammatory symptoms that have nothing to do with histamine, right? There are lots of mechanisms in the immune system that can give you cell-mediated inflammation or humoral, like antibody-mediated inflammation, different things. And mast cells are kind of an IgE thing, but it’s way more complicated than that.And when you work with these people, because a lot of them have found me because they have a very difficult time finding answers and solutions. I’ve been at most of us in this field have been at the bottom of a funnel where the options decrease because you try more and more therapies and they don’t work and the desperation increases kind of inversely proportionally. And then they’re trying weirder and weirder things that like people think are bizarre, you know, like you can eventually sting yourself with 20 bees a day, do apitherapy or something. Dr. Deb Muth 24:36I remember that therapy. And you know, as a practitioner too, it becomes more and more frustrating because it’s like, I’m trying all these things and nothing is working. What am I missing? And you keep trying different things until they just give up on you or you give up on them or whatever ends up happening, you know. Tyvincent 24:52Right. But again, like philosophically, every failure should lead you a step closer to success. Dr. Deb Muth 24:58Yeah. Tyvincent 24:58If you can look at it and you can learn from it what is possible from it and go, okay, I got to do this different or change this, or perhaps my entire theory about this problem is just dead wrong. Yeah. So if what I think is happening isn’t what’s happening, what else could be happening? And then you, you know, you come up with a theory and then you have to devise a way to test test it. And so like a lot of people probably tossed around theories about things being immune related or whatever over the years because it becomes a little obvious at a certain point, but they didn’t have a tool to test the theory.So that was the, the unique position I found myself in from 2009 onward was I’ve got a way to test this if I can figure out what antigen to try. And so I got a lot of mast cell people with that diagnosis. And, you know, my assessment of the problem is that when they come into my office, because like you and like most of people that are kind made it a little further in the integrative medicine world. The patients that find you have already seen 20 of your colleagues at the Mayo Clinic and the Cleveland Clinic and Germany, like Mexico, whatever. They’ve had exosomes infused up their nose or whatever. Like, all right, so what has not been explored yet? And you got to realize, okay, these, these people are there’s something going on. It’s very inflammatory. It’s probably immune related, but where is it coming from? Again, you mentioned root cause. You’ve got to trace the steps backward and try to figure out where is the point of intervention that will actually work and that’s feasible. And so what I found in these people, most of them have a pretty common early story of having had one or a few immune reactions that first began the process. And they might’ve been fairly benign and not that big of a deal.And then they go through some kind of immunological stress, whether it’s, well, some kind of stress, whether it’s a direct immune stress, like a vaccination or an infection or something like that. Like with COVID I’ve had an equal number of people who developed chronic immunological disorders after having the virus infection or having the vaccine. And the things that develop are virtually identical. So people are like, I should be gotten the vaccine. I’m like, it really doesn’t make any difference. Dr. Deb Muth 26:53Right. And I’ve seen the same thing with the HPV vaccine too. Like a lot of young people, they get that and all of a sudden their whole system is torn off after that. It’s very common. Tyvincent 27:03Except in that example, just getting HPV doesn’t do it. It’s the vaccine that does it. Dr. Deb Muth 27:07Vaccine that does it. Yes, exactly. Tyvincent 27:10Because everybody’s got HPV, you know, some other, and that is not in and of itself enough of an inflammatory trigger to lead to these chronic illness, right? You can lead to cancer, sure. Which is focal and it’s not a hypersensitivity problem. It’s a failure of immune defense problem. It’s a little different. So I would get these people and I’m like, okay, what happened first? What’s the beginning of the story? Because if you talk to them about how they’re feeling today, and a lot of your listeners, this will resonate with them. If I ask you how you’re doing today, the real cause of your problem is buried under a snowstorm of constant inflammation and your life experience is utter hell. And you have no clue what’s really triggering anything anymore. It’s like at a certain point, the immune system has developed PTSD, right? It’s just, it’s hypervigilant. Anything you give these people to take, even like vitamin C or whatever, then they go, ah, it made me worse.Ah, it made me worse. Because their immune system is now seeing anything foreign as an invader, as an enemy. So if you ask people just about how they’re doing today, you get absolutely nowhere. With these people. The one theory I had though was, well, maybe they’re reacting to histamine itself. Okay. I think is a beautiful theory. Makes total sense. Didn’t work at all. Spoiler alert. It’s not that it doesn’t work. It’s easy to get a sample of histamine, you know, and I also, I also got histidine, the amino acid from which it’s derived. I’ll say I’ll just put them together. So at least I want to say 12 years ago, I made like a histamine histidine LDI and everyone who had kind of the mast cell picture portfolio of illnesses, I would try it on. It has to this day, it’s never worked for anybody that I’ve tried it on. And I haven’t had another LDI practitioner tell me that it did. But again, that failure made me think about it in a different way. And so the success I’ve had with that population is not monolithic. It’s not one part. From an LDI perspective, figuring out what it is that they began to react to first, like, did you still have, do you have food problems originally?Oh yeah, I was kind of sensitive to gluten, but I just ate it anyway because I would just get some diarrhea and some, okay, it it was, it was livable, right? But they just keep exposing themselves to this trigger. And eventually something snaps in their immune system. Like they live in a moldy dorm room for 6 months and that all of that immune activation will kick off whole new immune response problems. And the world of mold is another area where I think people don’t, do not really understand what’s going on. And a lot of our treatment approaches don’t work for a large portion of these people. And it has to be kind of thought of in a broader sense. They could go through a divorce. They could have a car accident. They could have a surgery. A woman could have a baby, which is one of the biggest immunological triggers, unfortunately, is having a baby or early pregnancy miscarriage even is enough to do. Emotionally stressful. It’s physically stressful. It’s immunologically stressful.And then it swings your estrogen back up and you get this hypersensitive profile. But so all of these, what I call catalytic events were common in these people. And it’s not just one, it’s any one of them. And what I found was if I could identify what their initial triggers were categorically, right? Environmental things, chemical things, food. And if I could desensitize them to those, everything would settle down. And, and that was, that’s been the key to working with those people. But they want to tell you how horrible their life is today. Dr. Deb Muth 30:17Yeah. Tyvincent 30:17And you got to listen to that because you need the connection. You need to understand what they’re dealing with. You need to understand what their baseline is so that you can compare going forward. But the answers, the solutions aren’t in that story. And the solutions are in the history. And like, what’s the first thing you remember? And all this, like, okay, well, let’s go with foods. Let’s go with chemicals, whatever. And if somebody has distinctly worst triggers, right? Because right now they react kind of to everything. Any foods that you absolutely don’t eat because they give you the absolute worst reaction pattern, right? Oh yeah, I can’t eat these things. They’re the worst. Okay, well, maybe we’ll start with those and you can use those foods as your test exposures to determine if the dose works each time. So that’s one of the things I’ve developed stylistically over the years is the use of a test exposure if we’re using an allergen extract so that you can confirm or deny whether the therapy worked, right? Because people will tell you, oh, I feel better.Turns out that’s not worth much. You really need like, I mean, And belief is a huge part of that. Placebo effect is a huge part of that. You want to find something relatively objective, you know, so will you still vomit when you have chicken? You know, cause that’s like, that’s pretty obvious. And then go with that, you know, or do you still get a rash when you put on a bandaid? I love it when people get rashes from contact cause they can show me pictures and it’s not subjective, turns out. But even those reactions can go away 100% with placebo doses. It’s fascinating how people respond to placebos. So anyway, I try to find like the root beginning allergens. And then a lot of these people also accumulate other target antigens as they go through their process of being ill. Their immune system is so upset and it’s, it’s also just blurry vision, right? It attacks anything. Angry dog on a chain. If you get close enough, it’ll bite you. It doesn’t care who you are. And that’s how their immune systems get.So finding the antigens that are root cause is key. But a lot of these people have developed over time total adrenal burnout. Out, right? Because they’re in state of chronic inflammation, everything. So I also found that I had to lean on my skill in bioidentical hormone therapy, which over all the years I’ve been in integrative medicine, the two major skill areas that gave me the best results in general were hormonal management and immunological modulation. I got so many of the prior failures I was able to solve with those two things. And so if I would support these people’s adrenal, like hormones, you know, DHEA, cortisol, to optimal levels, a lot of them, their symptoms would cut by half, number one. And you would have a little more clarity as to what their actual triggers were.So in a lot of these cases, I learned to start with that before I even decided what antigens to pick. You can kind of get the snowstorm to calm down. You can start to find the snowmen in the blizzard that you couldn’t see before with all the chaos. I was like, okay, now that you’re feeling better most of the time, you can tell that these chemicals bother you, that mold exposure bothers you, that whatever, and then you can target things But the other third kind of leg of the tripod that I found are the keys to success with our most complex patients is to address like the hormonal issue, the immunological issue, but the subconscious fear response, the subconscious stress response in them. Dr. Deb Muth 33:14Trauma. Tyvincent 33:15And I saw that you’ve also people, yeah, trauma and people have medical trauma, not just trauma from their illness itself, but trauma from seeing 12 doctors that treated them like they were a head case and ignored what’s going on. Dr. Deb Muth 33:25Of the medical community, right? Tyvincent 33:27Oh God, you know, like people— yeah, the more doctors you see, the more your trust in doctors goes down. Dr. Deb Muth 33:34Yes, exactly. Tyvincent 33:35They see one of us and some of them just automatically are like, whatever, here’s another failure coming my way, kind of thing, you know, realistic. Partly because it becomes too risky to have hope, right? Like after a while you’ve had hope, hope, and it’s been dashed, and you just can only handle that so many times. It’s like you fall in love and then they dump W. And after a while you’re like, I’m celibate. I don’t care anymore. Um, so you get these people and what we have found, my wife and I started doing psychedelic-assisted therapy with patients a few years back. In fact, this little cottage on my property we built specifically for that purpose. People can come and stay here for a couple of days.There’s a bedroom on the other side of this wall. And we do therapy with them. We have a very good process of getting their hormones tested before they come, trying to correct any deficiencies or imbalances, especially cortisol and DHEA. We try to make sure that if they have immune problems that seem manageable, we maybe try to control those first. But in a lot of these people, we have to get their subconscious fire alarm to go off first because anything new that enters into their sphere of existence is seen as this, you know, scary thing. Dr. Deb Muth 34:36Yeah. Tyvincent 34:36And so what we found is getting their subconscious to settle down, getting them to integrate past whatever trauma they’ve had so that it’s no longer causing harm today from an experience 20 years ago, right? Because that’s not fair. A lot of these people, all of their immune stuff stops and I don’t even have to do LDI. And that’s fascinating. And some of them, we put them on hormone replacement, everything calms down enough. It’s like one of these things sometimes works. And in other people, they need all three. And the trick in those people is to figure out what thread you have to pull on first. You know, it’s like, well, okay. And we spend a lot of time, my wife and I both work with patients together. She’s amazing. She’s not a trained clinical clinician. You know, she had a business degree, but she’s like, she tells people I attended the school of Dr. Ty Vincent for 10 years. Dr. Deb Muth 35:20Yes. Tyvincent 35:21Heard him say all this a million times. And when we first started seeing patients from home together, she read all of my patient notes and just great. So she. Dr. Deb Muth 35:28Yeah, that’s how you learn. Tyvincent 35:30Yeah. And people like, well, I didn’t go she’s like, I didn’t go to medical school. I’m like, that’s an asset, trust me. Dr. Deb Muth (35:34-35:40)Exactly. Oh my God, you haven’t been brainwashed. Exactly. Tyvincent 35:40And you know, it’s not even so much washing as it is like throwing mud all over the walls. All of these false beliefs you’re given, and, you know, not just the beliefs, but the disbeliefs, both of those hold people back. And I was like, it’s your disbeliefs that are the bigger problem because you don’t even realize they’re there. Like when I learned about LDA, I’m like, that’s nonsense. No, it’s not. Dr. Deb Muth 36:02I’m curious, when you treat some of these complex people with LDI, are you using multiple modalities at one time, or are you being really cautious with them and using one at a time? Time, because some of them won’t let you do more than one thing at a time with them. Tyvincent 36:16And so by modalities, you mean like, are we also doing hormone therapy? Are they also doing like IV, like other things? Or you mean multiple antigens within? Dr. Deb Muth 36:24Multiple antigens, yeah. Tyvincent 36:25Um, it really depends. And early on, so I everything I know about LDI, I learned through experience, paying attention, putting connecting dots over you. And it’s been been a very long process, right? Early on, like a kid in a candy store, you see a patient and you find out, oh, they’re allergic to some foods, they’re allergic to some chemicals, they’re allergic to cats and birch tree pollen, and they also have psoriasis or whatever. And you’re like, ooh, I’m going to give you all 4 of these antigen mixtures because you have all 4 of these issues. And by 6 months in, if you’re paying attention, you are completely confused and lost. Dr. Deb Muth 37:03Yeah. Tyvincent 37:04I did that for a number of years and I thought, well, this will be the fastest way to figure things out. It turns out it’s not, unfortunately. Um, what I’ve found is more successful is if I can figure out either what the most important underlying immune reaction is for them that might be cascading into other problems, or you figure out what’s the easiest one to solve first. So if somebody has like the whole mast cell picture and they got all this stuff going on, but they say the biggest thing is I have horrible chemical reactions. I’m a tr I’m trapped in my home. I created an oasis of safety here, but I can’t go anywhere. Anyone who comes to my house has to go into the entryway and take all their clothes off and put on a jumpsuit, right? There are those people. I work with them. Dr. Deb Muth 37:40Oh yeah, I have those clients. Tyvincent 37:42They’re like, oh my God. Well, if we can fix that first, your world will open up a ton. Your fear will come down. Your immune response will come down. And so sometimes it’s a matter of which one seems the most important or which one seems easiest. Like, okay, the test exposures that they have are the most obvious and distinct. For foods and not chemicals or whatever. And the reactions people have to these different antigens can overlap tremendously or even look exactly the same, which is why you kind of need to use one at a time. Because if you’re trying to ride a bike and a motorcycle at the same time, it doesn’t go so well. Dr. Deb Muth 38:16Yeah. Tyvincent 38:16Like, let’s find where you do with where you respond to this one, and then we will have less stuff to deal with. We might have a little bit more clarity as to what you’re reacting to in other categories. And then you kind of go through them sequentially. But if I have somebody who’s not like just in a real state of immunological distress like that, and they go, yeah, I’m allergic to cats and I have a cat because I’ll never get rid of my cat. I don’t understand those people, but, but there are a lot of them. They love their cats. Dr. Deb Muth 38:43A lot of them. Yes. Tyvincent 38:44I’m like, okay, or dog, you know, I’ve had people that are horribly allergic to dogs and the dog still sleeps in bed with them every night. Dr. Deb Muth 38:50Okay. Tyvincent 38:51Um, they’ve got that, that’s very clear, very distinct. And it’s, and it’s like a rash or a runny nose. And then they also have have celiac disease, let’s say. Like, well, we can treat both of those at the same time because the symptoms are totally different. You have test exposures in both categories and you’re not so sick that you’re in a constant state of like trauma response where you can’t even pay attention to anything. Right. And so it’s kind of case by case. And my style is very, very individualized. Like I said, there’s never a protocol. It’s like, I got to talk to people for about I usually talk to people for about an hour. Yeah. More than isn’t really helpful. You know, like, in an hour of time, you’re, you’re kind of saturated with how much you can invest your bandwidth into this particular issue. Now, like, okay, I know where we’re going to start. I don’t know where we’re going to end up, but I know where we’re going to start. And so we encapsulate that and then go, let’s do this. And then everything you do teaches you more about what else you need to do.And it’s a process. I my ego used to be more tied to guessing correctly at the beginning about what was going to work work and to fixing things quickly. And over time I realized like your ego really has no place in the exam room. Like that is a very, very challenging thing for practitioners to try to figure out is how to get your ego out of this because it biases you intellectually, emotionally, and it’s a problem. And our medical colleagues probably have bigger egos than the average human in the population. Let’s be honest. Um, there’s something that comes with the years of study and the investment and the status you have, and it’s a challenge. But if you be like, I just need to be clear about what’s happening, what’s not happening, and you figure things out. And so I was able to have a much better success rate approaching things that way.And every time you put out one little fire for people, one kind of immune response, it, you, you get a better picture about what else is going on. And then eventually all their problems have stopped and you’re okay, cool. I guess we’re done. But it’s, it’s hard. And you do learn that there are still major gaps in your knowledge. And, and you asked earlier about new developments in LDI. And whatnot. And I could literally talk all day about the things that I’ve developed over the years, but I still keep making new antigens. So just last year in the area of food allergy, so like your Mast Cell people, a lot of them have food allergies that are a big part of the underlying problem, and this will be relevant to them. But what I found is a lot of the people who seem to clearly react to food, and I put food in quotes because most of what Americans eat isn’t food, right? It’s it’s at least it’s not just food, or it used to be food and now it’s not. It’s like Frankenfood, and it’s got chemicals in it. It has molecules that don’t exist in nature, so you can react to them.So I found some of these people that would say, oh, I react to processed food items horribly, but if I eat the whole foods, organic whole foods at home, I don’t react. And, um, some of those people will resolve those problems with the chemical LD mixture. So they’re reacting to chem with that. A lot of them will tell you, oh, I also react to perfume. Or gasoline or whatever. Dr. Deb Muth 41:46Yeah. Tyvincent 41:46Okay. And so you can use that and some of those cases will resolve, but a lot of them don’t. And I had increasing failures. Like I’ve been doing this long enough to see and observe that early on I had much better success with these antigen mixtures than over time. People are the pattern and the causes and the manifestations of illness today are evolving right before our eyes because of what we’ve done to our environment and our food and ourselves. So what I came to to sort of theorize about was that maybe some of these people are reacting to processed cooking oils, like seed oils, plant oils that are put into processed foods, right? Because they would tell me a couple of key cases gave me that insight. They would say, well, I still react to all these processed foods.I can’t eat at restaurants, and I’m still reacting horribly to sesame seeds, or I’m still reacting horribly to flax, or I’m still reacting horribly to, like, one of these other things we make processed seed oils from. Well, maybe they’re reacting to the oils. And when we made the food mixture, you use whole food samples, right? So you use like a, a ses like sesame seeds, or I use tahini paste because it’s easier to mix in water. But maybe the antigen, the target antigen, is something inside that that is not properly like, what’s the word I’m looking for properly given to the immune system, or, or like exposed, shown to the immune system, right, in the way that their immune system is reacting to it. Maybe it’s a molecule in there that when you use a whole food antigen is not adequately represented. It’s like, so an oil would do that.And I had actually already years ago realized that some people react to essential oils, like flower extracts or tea tree oil or lavender or whatever. Right. And so I made an essential oils mixture from plant oils from the doTERRA and the Young Living products. I had a couple of patients that were like distributors for these things. And I said, just take an empty vial and put one drop of every single product you have in it and just mail it to me. And they both did that. So I have this huge compendium of essential oils, and I would get people that would still react to oranges and lemons and citrus fruits despite the food mixture. And then the essential oils mixture would totally stop that reaction. So I’d already kind of proven that this was the case with some of those more aromatic oils, right? Now I was like, well, people are reacting to the processed cooking oils because when you take oils out of the plant, if you ever do this at home, they’re opaque and gooey and viscous. And then somehow it’s this really pretty homogeneous, clear liquid that doesn’t separate at all. It has no nothing you see in there.And then you got to wonder, how the hell did they do that? What did they do to make that? And there are all these chemical processes and heat and everything. I’m like, well, it just makes new molecules that your immune system has never seen before. So in May of 2025, I bought 18 different kinds of plant oils, and some of them are really pure, like carrot seed oil, cottonseed oil. But there’s peanut oil and avocado oil and olive oil and, you know, all the seeds and things we use in there. And I even have a video on our Facebook page and probably Instagram of me making this mixture in my kitchen.I was like, people are kind of interested how this works. And I just made it right there on camera because it’s really simple. I started using it in some of my failure cases that had really seemed like they had food allergy responses, but the food mixture didn’t work. And the first one was actually one of our employees who does our social media management. She had a 3-year-old son, I think, probably 2 years old when we started working with him, with really bad body-wide eczema, right? And he never really responded to the food mixture, essential oils, skin bacteria, skin fungi, yeast. I tried all the things that usually work. I’m like, it’s something. And so he made the oil mixture. He was they were the first one. I just sent the doses like, hey, let’s check it out. And I think he got for I started 6C for most things, which is a truly and then it’s like 5.5C, 5C. We got to 3.5C, I think, is where he is, which is a dilution of of 10 million to 1, I believe. And 95% of his eczema just completely went away. Dr. Deb Muth 45:38Wow. Tyvincent 45:39The only thing left was a couple of those patches on his feet. And one of the things I learned about people with eczema is they will have localized, like geographically local consistent reactions to different things. This is crazy, right? Dr. Deb Muth 45:53Yeah. Tyvincent 45:53Your immune system has kind of a, you know, like an overall regulatory system, but it also has regionalized systems, just like the government federal government, state government, county government, city government. It’s, it’s divided like that. So the people will eventually learn, oh, if I eat gluten, I get these itchy bumps on the side of my hand, and if I eat carrots, I get a rash on top of my head, you know. And it’s very, very clear once you identify it. So there’s still something that kid’s reacting to that I haven’t quite solved on his feet. But, um, yeah, that worked amazingly, and it actually made me cry when I got the pictures She’s like, oh, finally, after probably a year and a half of flailing, you know, we got it right. And so now I’ve been using the cooking oils mixture more and more and more. Just yesterday I got an email. I have a teenager, he’s 8, he’s maybe 18, 17, 18, with just really horrible cystic acne, painful, erupting. And the before pictures are just hard to look. I mean, he’s got horrible involvement of both sides of the face, the chest, all over his back, and you can just see the scarring and the redness and the inflammation.And we went through the food mixture with him and whatnot, and it really didn’t touch it. So yesterday I got the report. He got up to the cooking oil mixture at 2.5C, which is 10,000, 100,000 to 1, and, and his cystic acne stopped. Like, he’s getting zero new lesions. All the redness, pain, inflammation is gone, but he still has all this just scarring from it because that’s permanent, right? You have to get that repurposed. And all he has left is little tiny whitehead pimples, like maybe one new one per day here and there. You can see them now in the midst of all this. So acne is diversified. There are different kinds of acne and people can have more than one type and they can react to hormones. They can react like I’ve had guys with bad acne respond to desensitization with testosterone, for example, or women desensitizing them to estrogen or progesterone and the acne will go away sometimes. Some people respond to yeast, some people respond to skin bacteria, skin fungi. And so this is another thing. And my wife actually is one of the more complicated immunological cases I’ve ever had to work with. Working together for 10 years, um, you know, like the first time I saw her, she had Lyme disease and the Lyme LDI just totally stopped those symptoms like magic, which is great.That’s one of my favorite things to treat. Um, because the beliefs we have about Lyme disease, I have found completely untrue because using a different tool. I’m like, oh, it’s an immune problem, not an infection. So anyway, so that, that worked for her. Some of her food reactions went away, but she still continued to get like deep painful cysts if she would have nuts or dairy. And so the cooking oil mixture now, after 10 years of being together, totally stopped those reactions. Peanuts, nuts, dairy. And the dairy one is interesting to me because it’s not a plant oil, right? It’s an animal oil and it’s not represented. And we have dairy products in our other mixture. But I think what’s happening is when cows are fed grain, sometimes what an animal is eating carries through some essence or nature of that substance into the milk. Um, and the thing I’ve seen this the most clearly with is corn. Corn allergy is a very unique situation. The way people deal with it, the way it manifests, the way you have to treat it is different from every other energy. And I don’t have an hour to talk about that specifically, but I observed primarily with corn that anywhere along the food chain, you’ll still react to that food if the animal at the beginning was ever fed corn. Multiple I’ll have babies that get an eczema reaction or a GI reaction if mom eats corn-fed beef. But if mom eats grass-fed beef and then nurses the baby, they’re fine. Dr. Deb Muth 49:33Yeah, I’ve seen that too. Tyvincent 49:34It’s bizarre. Dr. Deb Muth 49:35Yeah. Tied. This has been really so amazing. Um, tell us how people can find you if, if this is resonating with them and they’re like, I need him to figure out the puzzle for me. How do they find you? Tyvincent 49:49So the best thing to do is to go to our website. Our, our business name is Global Immunotherapy, and the website is just http://www.globalimmunotherapy.com. We have, we have a much better website than we did years ago. People schedule directly through the website. Right? There’s all kinds of information. I’ve been making YouTube videos and informational videos for people for more than a decade now because nobody has any idea what I’m talking about. The more they understand it beforehand, one, they get to decide if they just think I’m crazy, right? And they don’t want to waste their time. And there are plenty of those people, but a lot end up talking to me 3 years later because after they’ve tried everybody else and there’s nothing left to try, right? Yeah, yeah, like being at the bottom of the desperation funnel. Yeah, people like, well, I heard about you 5 years ago and didn’t make sense. I’m like, yeah, cool. But then I had 3 or 4 other people over the years tell me I should talk to you. So here I am. That’s, that’s right. And people can watch all these educational instructional videos about how LDI works, what it can be used for. So the more you learn and understand what you’re getting into ahead of time, the less time we have to spend during our hour trying to explain to you the therapy., which to take up half the time and better results you’re going to get because you’re educated and it’s a partnership.Like all of us in the world of integrative medicine, one of the big differences between us and conventional medicine is we understand that it’s a partnership. You have to listen to the patient, you have to educate the patient, you have to engage them in their own health. You can’t just say, here, take this pill and come back in 3 months and I’ll check your labs again to see that you still have the same illness. It’s just and people have a lot of our population has been led to believe that just swallowing a pill is going to fix your problems. But That doesn’t work. And we have to develop a relationship and an understanding and shared knowledge and beliefs. And so people now, they have this opportunity to watch all the videos. And I really want people to do that before they ever schedule, because one, you’ll, you’ll feel like it’s the right therapy for you. And that helps a lot. Having optimism going in is super helpful. And then two, you already know a lot. So you’ll know more about what questions I might ask you and how to answer them. You’ll know more about about how the therapy works, and I won’t have to explain it to you, and we’ll get a better use of our time. And then people can schedule right through the website with either myself or my wife Jeanette. And anybody who Jeanette talks to, she reviews every case with me, and we work together with stuff. And, but in terms of like using LDI, she’s probably the second or third best practitioner in the world. I

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