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Join us for this exciting episode as Dr. Debbie Ozment, DDS shares practical, simple, and valuable strategies for enhancing life and maximizing vitality. As the host of the Vitality Made Simple podcast, Dr. Ozment is an expert in the early diagnosis and intervention of periodontal disease. By taking the stress out of being healthy, she addresses key concerns such as chronic inflammation, toxins, and emotional anxiety — issues known to drain people of their energy and wellbeing… This discussion outlines: How small, sustainable lifestyle habits can significantly extend your vitality span. The connection between oral health, systemic inflammation, and chronic disease prevention. Simple ways to lower stress and improve overall wellbeing through an integrative, preventive approach. Dr. Debbie Ozment has been a private-practice dentist since 1985. A graduate of the University of Oklahoma College of Dentistry, she also served as adjunct faculty there for seven years. Dr. Ozment earned a Master's degree in Metabolic and Nutritional Medicine from the University of South Florida Morsani College of Medicine and is a Diplomate of the American Academy of Anti-Aging Medicine. Trained at the Mayo Clinic, she is also a National Board-Certified Health and Wellness Coach. Want to discover how Vitality Made Simple provides listeners with sustainable solutions for maximizing their vitality span? Tune in now to hear Dr. Ozment's refreshing Integrative Medicine approach, which unites physical, mental, and emotional wellbeing into one cohesive and actionable framework. Follow Dr. Ozment on Instagram @drdebbieozment for her latest updates and insights
Fibroblast growth factor receptor 2 isoform IIIb (FGFR2b) is an emerging biomarker present in about 38% of patients with advanced gastric or gastroesophageal junction (GEJ) adenocarcinoma. In this episode, CANCER BUZZ speaks with Nataliya Uboha, MD, PhD, a medical oncologist at University of Wisconsin Health, about current recommendations for biomarker testing in this population, emerging biomarkers such as FGFR2b, and how multidisciplinary collaboration can ensure patients receive timely biomarker testing. CANCER BUZZ also interviews Wendi Waugh, BS, RT(R)(T), CMD, ODS, FACCC, administrative director of cancer services and ambulatory infusion at Southern Ohio Medical Center, about care coordination strategies and lessons learned from her team's experience administering biomarker testing. Finally, Kristina A. Matkowskyj, MD, PhD, pathologist at Mayo Clinic, explains the vital role of pathologists in identifying biomarkers and strategies for success in biopsies. "We have to work closely with our pathology colleagues to make sure that all of the tests are done quickly and so that they are readily available by the time the patient is seen in clinic." - Nataliya Uboha, MD, PhD "Tracking, knowing what and when new things come out, being able to mine your data to find those things, I think is going to be uber critical." - Wendi Waugh, BS, RT(R)(T), CMD, ODS, FACCC "I believe that the precision medicine testing that we're doing today... is going to change the face of cancer care." - Wendi Waugh, BS, RT(R)(T), CMD, ODS, FACCC "As a pathologist, if I was able to stress one thing, it would be to collect as many biopsies as is safely possible for that particular patient." - Kristina A. Matkowskyj, MD, PhD Guests: Nataliya Uboha, MD, PhD Medical Oncology University of Wisconsin Health Madison, WI Wendi Waugh, BS, RT(R)(T), CMD, ODS, FACCC Administrative Director of Cancer Services & Ambulatory Infusion Southern Ohio Medical Center Portsmouth, OH Kristina A. Matkowskyj, MD, PhD Pathologist Mayo Clinic Rochester, MN
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, welcomes William Morice II, M.D., Ph.D., president and CEO of Mayo Clinic Laboratories. Together, they discuss recent news about virus activity and explore the value of collaboration in shaping innovative diagnostic strategies. Testing for viruses appearing closer to home (00:45): Gain insights on using available testing to manage measles and detect chikungunya, which was recently transmitted in the U.S. for the first time in years. Collaborating for more coordinated care and innovation (06:04): Explore how strategic partnerships in diagnostics foster innovation and enable a more integrated approach to clinical decision-making.Building successful collaborations (12:16): Discover practical insights into establishing and maintaining collaborations that deliver meaningful value to all involved. Note: Information in this post was accurate at the time of its posting.ResourcesAnswers From the Lab Podcast: How the Evolving Role of Diagnostics and Platforms Impact Healthcare: Bill Morice, M.D., Ph.D. Dr. Bill Morice shares how a platform for collaboration transforms diagnosticsMary Jo Williamson offers four steps to maximize collaboration benefits
Today, Jenny and Mr. John dig into some new research and more real talk yet again! From optimal resistance training or results to ultraprocessed foods and putting an end to type 1 diabetes, the research is coming in hot! And don;t miss John's Real Talk about education in the fitness fields- it comes in many shapes and ways! Happy listening!References: 1. Comparable Strength and Hypertrophic Adaptations to Low-Load and High-Load Resistance Exercise Training in Trained Individuals: Many Roads Lead to RomeKristoffer Toldnes Cumming, Ingrid Cecelia Elvatun, Richard Kalenius, Gordan Divljak, Truls Raastad, Niklas Psilander, Oscar Horwath bioRxiv 2025.04.28.650925; doi: https://doi.org/10.1101/2025.04.28.6509252. Samuel J. Dicken, Friedrich C. Jassil, Adrian Brown, Monika Kalis, Chloe Stanley, Chaniqua Ranson, Tapiwa Ruwona, Sulmaaz Qamar, Caroline Buck, Ritwika Mallik, Nausheen Hamid, Jonathan M. Bird, Alanna Brown, Benjamin Norton, Claudia A. M. Gandini Wheeler-Kingshott, Mark Hamer, Chris van Tulleken, Kevin D. Hall, Abigail Fisher, Janine Makaronidis, Rachel L. Batterham. Ultraprocessed or minimally processed diets following healthy dietary guidelines on weight and cardiometabolic health: a randomized, crossover trial. Nature Medicine, 2025; DOI: 10.1038/s41591-025-03842-03. Mayo Clinic. "This sugar molecule could stop type 1 diabetes, by fooling the immune system." ScienceDaily. www.sciencedaily.com/releases/2025/08/250802022917.htm (accessed August 2, 2025).
In today's episode, we had the pleasure of speaking with Sikander Ailawadhi, MD, and Beth Faiman, PhD, MS, APN-BC, BMTCN, AOCN, FAAN, FAPO, about the potential clinical implications of the phase 3 IRAKLIA (NCT05405166) and phase 2 IZALCO (NCT05704049) studies, which investigated the use of isatuximab-irfc (Sarclisa) administered via an on-body delivery system in patients with relapsed/refractory multiple myeloma. Ailawadhi is a consultant in the Division of Hematology/Oncology in the Department of Internal Medicine, a consultant in the Department of Cancer Biology, and a professor of medicine at Mayo Clinic in Jacksonville, Florida. Faiman is a nurse practitioner in the Multiple Myeloma Program at Cleveland Clinic in Ohio. In our exclusive interview, Ailawadhi and Faiman discussed the rationale for efforts to bring isatuximab on-body injectors into the clinic, key patient-reported outcome findings from these studies, and how these findings may one day influence therapy administration across the broader multiple myeloma treatment paradigm.
Today we have Dr. Marina Walther-Antonio, a Mayo Clinic researcher who investigates the role of the microbiome in cancer and reproductive health, particularly endometrial and ovarian cancers. According to the World Cancer Research Fund International, endometrial and ovarian cancers are among the top 10 most prevalent cancers in women worldwide, and there are still no standard screenings for early detection. Marina is an assistant professor in the Department of Surgery and the Mayo Clinic Center for Individualized Medicine Microbiome Program. She has a joint appointment in the department of Obstetrics and Gynecology. Today we talk to Marina about how she and her colleagues are utilizing the methodologies of environmental microbiology and technologies used in astrobiology to improve our understanding of endometrial and ovarian cancers. Through her investigations into the microbiome, she and her team are developing early detection tests that will enable clinical interventions before certain cancers develop. Show notes: [00:03:13] Dawn opens our interview asking Marina about the history of her interest in extraterrestrial life. [00:05:49] Dawn mentions that Marina did her undergraduate studies in Portugal at the University of Aveiro, where she majored in biology. Dawn asks why Marina chose biology as her major. [00:06:39] Ken explains that the undergraduate programs at Aveiro University require students to do a year of research outside the university and asks Marina about her experience with this requirement. [00:08:34] Ken explains that while Marina was conducting her internship at NASA Ames Research Center, there were several projects under way at the astrobiology institute, with the one that Marina was assigned to looking at a Mars analogue site in Oregon's Warner Valley. Ken asks what kind of work Marina did on this project. [00:10:06] Ken asks Marina why after earning a master's degree in microbiology from Indiana University, she went to Washington State University to earn a Ph.D. in environmental sciences. [00:13:29] Dawn asks about Marina's Ph.D. research on microbialites, which are microbial structures that can thrive at the bottom of certain freshwater lakes and other extreme environments. [00:16:02] Dawn explains that just as Marina began researching microbial populations, the Mayo Clinic Center for Individualized Medicine created a microbiome program. Dawn asks Marina about the circumstances that led to her joining Mayo. [00:19:05] Dawn mentions that Dr. Claire Fraser, the director of Maryland's Institute for Genome Sciences pointed out in Episode 32 of STEM-Talk that there are more microbes on a single person's hands than there are people on Earth, as well as the fact that our gut is home to more than 100 trillion bacteria. Dawn asks Marina to talk about this microbial side of humanity. [00:21:51] Ken mentions that if listeners are interested in learning more about the microbiome and how it affects human health, they should listen to Episodes 20 and 168 with Dr. Alessio Fasano. Ken asks Marina to give a short overview of the microbiome. [00:25:37] Dawn asks Marina how the focus of her research shifted to the role of the microbiome in cancer and reproductive health. [00:29:00] Dawn explains that endometrial and ovarian cancers are among the top 10 most prevalent cancers in women worldwide; with ovarian cancer being the most common gynecological malignancy and the fifth leading cause of death due to cancer in women in the nation. Dawn goes on to explain that in a 2023 paper Marina investigated the area of microbiome that is associated with ovarian cancer to better understand the microbiome's potential in early detection. Dawn asks Marina to talk about this study and its findings. [00:35:55] Given the small scale and sample size of her initial study, Ken asks Marina what her ideal follow-up study would look like. [00:38:37] Ken mentions that in 2019 Marina published the r...
In this episode, Antonia and Andrew discuss the November 5, 2025 issue of JBJS, along with an added dose of entertainment and pop culture. Listen at the gym, on your commute, or whenever your case is on hold! Link: JBJS website: https://jbjs.org/issue.php Sponsor: This episode is brought to you by JBJS Clinical Classroom. Subspecialties: Spine, Knee, Hip, Basic Science, Pediatrics, Pain Management, Rehabilitation, Orthopaedic Essentials, Education and Training Chapters (00:00:03) - JBJS: Cases on Hold(00:02:05) - Case on Hold(00:02:53) - This Week's Orthopedic News(00:04:37) - The Broken Wing Sign(00:09:32) - Broken Wing Sign test, sensitivity and specificity(00:14:45) - Does BMI change after total hip and knee arthroplasty?(00:21:48) - Knee and hip replacement: Does this particular study change my practice(00:27:06) - Mayo Clinic orthopedic care: Future of weight loss(00:28:27) - Vitamin C and CRPS after total knee replacement(00:37:40) - Vitamin C pre-cancer screening(00:38:41) - Honorable Mention(00:39:48) - The pelvic inclination angle in congenital cervical scoliosis
On this episode of The Medical Alley Podcast, we're recognizing Alzheimer's Awareness Month with three special guests: Dr. Brandy Matthews (VP, Global & US Medical Affairs, Alzheimer's Disease at Eli Lilly and Company), Dr. Ronald Petersen (Neurologist, Mayo Clinic Alzheimer's Disease Research Center), and Robert Freeman (VP, Public Policy, Alzheimer's Association, MN-ND Chapter).In the discussion, we break down what Alzheimer's Disease is, how it's diagnosed, the latest innovations in research and treatments, and what the future of Alzheimer's care could look like.Send us a message! Follow Medical Alley on social media on LinkedIn, Facebook, X and Instagram.
Homes That Heal | Transform Your Home Into a Health and Wellness Sanctuary
Ep 73 | If midlife has felt dim lately—foggy energy, sluggish metabolism, restless sleep—you're not alone.This episode with holistic health educator and podcast host Kellie Lupsha is about learning how to turn the lights back on—through natural GLP-1 activation for women, gentle rhythms, and steady healing that meets you right where you are.Because your body doesn't need more pressure. It needs permission to rest, rebalance, and shine again.We talk about healing your genes naturally, resetting metabolism and hormones, and finding peace in a world that never stops pinging you for attention.If you've been feeling tired, disconnected, or overwhelmed by wellness “shoulds,” this conversation is the midlife reset you didn't know you needed.We cover:[01:00] – Welcome[11:00] – Kellie's journey from PT to women's wellness educator[17:10] – The real foundations of wellness: sleep, hydration, movement, and self-nurturing[22:10] – Why supplement overload is a modern epidemic (and how to simplify yours)[25:40] – Gene activation and GLP-1 explained: turning your body's switches back on naturally[32:20] – The real cause of exhaustion: decision fatigue and constant notifications[37:15] – Kellie's upcoming virtual women's wellness summit (plus how to join for free)Meet Kellie Lupsha:Kellie Lupsha is an expert on Women's Health and supports midlife women in achieving more energy, balancing hormones & improving metabolic health. Kellie is passionate about teaching people to activate their genes to achieve root cause healing. She empowers women to optimize their wellbeing and longevity.She is foremost a mom of 4 adult kids and a true entrepreneur. Kellie received her bachelor's degree in exercise and sport sciences at the University of Arizona and her Masters in Physical Therapy at the MayoClinic.Kellie has been in the wellness and healthcare space for over 30 years as a Physical Therapist, wellness expert and business owner. Kellie coaches women with functional wellness memberships, health coaching and retreats. Kellie is the host of “Thriving in Midlife: Redefining Aging with Wellness.” Herultimate purpose is to teach people to become the CEO of their own health!“It is no longer an option, it is essential to take control of your health.”Resources:
Radiation Therapy and its Effect on the Heart and Cardiac Devices Guest: Nicholas Tan, M.D., M.S. Host: Anthony H. Kashou, M.D. Mayo Clinic electrophysiologist Dr. Nicholas Tan joins Dr. Anthony Kashou on this episode of “ECG Making Waves” to discuss how radiation therapy can impact the heart and heart rhythm. After listening to this podcast, listeners will have developed awareness of the complexities behind managing cardiac devices in cancer patients. Topics Discussed: What effect does radiation therapy have on the heart? What arrhythmias can be seen with radiation therapy? How can radiation therapy impact cardiac device management? Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode. Podcast episode transcript found here.
This episode features Heather Costa, Director of Technology Resilience at Mayo Clinic. With over two decades of experience building resilience programs at leading healthcare institutions, Heather has redefined what it means to prepare for and thrive through disruption. From Cleveland Clinic to Mayo Clinic, she's led enterprise-wide recovery strategies that balance people, process, and technology. In this episode, Heather explains why true resilience starts with leadership, not technology, how to set clear priorities when everything feels critical, and how to design organizations that adapt and recover faster. This is a powerful look at the mindset and methods behind building resilience that lasts in healthcare and beyond. Guest Bio Heather M. Costa is a leading authority in cyber and technology resilience, currently serving as Director of Technology Resilience at Mayo Clinic. With over twenty years of experience, she has shaped resilience programs at premier healthcare institutions, notably pioneering business resilience at Cleveland Clinic before architecting Mayo Clinic's enterprise-wide recovery and continuity initiatives. Heather is a dynamic leader, keynote speaker, and mentor, frequently invited to share her insights at organizations and conferences such as Harvard NPLI, HIMSS, and the HIPAA Summit. She is recognized for building high-performing teams and fostering the next generation of cybersecurity leaders. Heather holds a Master's in Homeland Security – Information Security and Forensics from Penn State, a summa cum laude Bachelor's in Emergency Management from the University of Akron, and multiple esteemed certifications including Certified Business Continuity Professional (CBCP), Certified Cyber Resilience Professional (CCRP). She is Vice President for the WiCyS Healthcare Affiliate and a member of several distinguished honor societies. Outside of work, Heather is a dedicated solo mom to five children, inspiring her family and community with her resilience and leadership. Guest Quote "[Resilience] means not just recovering, but being better. Adapting, where we're wired in our DNA organizationally, to thrive in disruption, not just survive.” Time stamps 01:08 Meet Heather Costa: Cyber Resilience Expert 04:49 Understanding Resilience in Healthcare 22:36 Starting with Minimal Viable Recovery 25:56 Worst Case Scenario Planning 28:30 Building a Resilient Environment 29:33 Heather's Blue Sky Strategy Planning 35:26 What's Missed When Building Resilience 37:43 Final Advice on Resilience Sponsor The HIP Podcast is brought to you by Semperis, the leader in identity-driven cyber resilience for the hybrid enterprise. Trusted by the world's leading businesses, Semperis protects critical Active Directory environments from cyberattacks, ensuring rapid recovery and business continuity when every second counts. Visit semperis.com to learn more. Links Connect with Heather on LinkedIn Learn more about Mayo Clinic Connect with Sean on LinkedIn Don't miss future episodes Register for HIP Conf 2025 Learn more about Semperis
Things can get hectic during AEP. From sales appointments, applications, and following up with clients, it's easy to brush aside rest and self-care, so consider this episode as a reminder! Read the text version Save Time, Sell More - IntegrityCONNECT Contact the Agent Survival Guide Podcast! Email us ASGPodcast@Ritterim.com or call 1-717-562-7211 and leave a voicemail. Resources: A Review of Integrity's Top Medicare Quoting Tools Agent Survival Kits Do's and Don'ts of Medicare Compliance How Ask Integrity Can Streamline Your Medicare Sales Appointments IntegrityCONNECT - Login PlanEnroll – Take Your Business to the Next Level Ritter's Round Table Your Guide to Forming an Insurance Agent Network Fun Local Resources near Harrisburg PA: Lancatster Cat Cafe Meditation to Calm the Mind (Free) Round-A-Bout-Bagels Carlisle Cat Cafe Volunteer with The Harrisburg Humane Society (Free) Wildwood Park (Free) – Harrisburg PA Yoga at Harrisburg YMCA References: “3 Tips to Manage Stress.” Www.Heart.Org, American Heart Association, https://www.heart.org/en/healthy-living/healthy-lifestyle/stress-management/3-tips-to-manage-stress. Accessed 8 Oct. 2025. “Your Frontline Source for Tech News.” Techreport, 6 Oct. 2025, https://techreport.com/. Mayo Clinic Staff. “Stress Relievers: Tips to Tame Stress.” Mayo Clinic, Mayo Foundation for Medical Education and Research, 3 Aug. 2023, https://www.mayoclinic.org/healthy-lifestyle/stress-management/in-depth/stress-relievers/art-20047257. Matijczak, Angela, et al. “The Influence of Interactions With Pet Dogs on Psychological Distress.” American Psychological Association, American Psychological Association, https://psycnet.apa.org/fulltext/2023-97081-001.html. Accessed 8 Oct. 2025. Follow Us on Social! Ritter on Facebook, https://www.facebook.com/RitterIM Instagram, https://www.instagram.com/ritter.insurance.marketing/ LinkedIn, https://www.linkedin.com/company/ritter-insurance-marketing TikTok, https://www.tiktok.com/@ritterim X, https://x.com/RitterIM and YouTube, https://www.youtube.com/user/RitterInsurance Sarah on LinkedIn, https://www.linkedin.com/in/sjrueppel/ Instagram, https://www.instagram.com/thesarahjrueppel/ and Threads, https://www.threads.net/@thesarahjrueppel Tina on LinkedIn, https://www.linkedin.com/in/tina-lamoreux-6384b7199/ Not affiliated with or endorsed by Medicare or any government agency.
Running economy is one of the top performance determinants for long distance runners - but what exactly is it? Can your watch measure it? How do you improve it? We sit down with exercise scientist Dr. Shalaya Kipp to learn about running economy and what it really means for running performance.Thank you to our sponsors:✨ Previnex: Previnex creates clinically effective, third-party tested supplements made with high-quality ingredients, including Muscle Health Plus (creatine). Use the code treadlightly for 15% off your first order at previnex.com✨ Amazfit: User-friendly simple running watches with advanced features, at an affordable price point. Use link http://bit.ly/4nai73H for 10% off your purchase.In this episode, you will learn:✅ What is running economy?✅ Why does running economy matter, especially for the marathon?✅ How do you measure your running economy?✅ The impact of supershoes on running economy✅ How to train to improve your running economy✅ Why carbohydrates improve your running economy?✅ Does stretching alter your running economy?✅ How your sports bra and other running gear impact your running economyAbout Our Guest:Shalaya Kipp is a postdoctoral research fellow at the Mayo Clinic in Rochester, Minnesota, where she studies human exercise performance. She earned her PhD in Kinesiology from the University of British Columbia, where her research focused on respiratory mechanics during exercise with a specific interest in sex differences and aging. Before that, she completed her master's degree in Integrative Physiology at the University of Colorado Boulder, investigating the biomechanics and energetics of human running, including foundational studies on Nike's groundbreaking 4% VaporFly shoe.Beyond the lab, Shalaya brings her own athletic experience as an NCAA champion and nine-time All-American in track and field. She specialized in the 3000m steeplechase and represented the United States at both the World Championships and the 2012 Olympic Games. CurrentlyShalaya enjoys stroller runs with her 2-year-old daughter and 4-year-old son.You can connect with Dr. Kipp on Instagram!Let's stay connected:➡️ Tread Lightly Running Podcast on Instagram: https://www.instagram.com/treadlightlyrunning/➡️ Laura Norris Running on Instagram: https://www.instagram.com/lauranorrisrunning/➡️ Hundreds of evidence-based training tips on Laura's website: https://lauranorrisrunning.com/➡️ Run to the Finish on Instagram: https://www.instagram.com/runtothefinish/?hl=en➡️ Thousands of running gear reviews and training guides:https://runtothefinish.com/
In this powerful and eye-opening conversation, Leanne Woehlke sits down with Dr. Ruchir Gupta, a double board-certified pain specialist and founder of Mountain View Headache and Spine Institute, to explore the evolving world of chronic pain treatment and clinical research.Dr. Gupta shares his journey from anesthesiology into chronic pain medicine and research, highlighting why traditional approaches often fail and how emerging therapies like ketamine infusions and stem cell treatments offer new hope. Together, they discuss the importance of changing the language around "experimental" medicine, improving access to clinical trials, and educating patients and physicians about cutting-edge but underutilized treatments.They also tackle:The broken incentives in insurance-driven medicineHow to ethically introduce new treatments to patientsThe power of AI and EMRs in revolutionizing clinical trial recruitmentRebuilding trust in the medical system through transparency and educationThis episode is a must-listen for healthcare professionals, clinical researchers, and patients seeking alternatives to outdated treatments and a deeper understanding of how clinical research can drive real change in patient care.Dr Ruchir Gupta:Dr. Ruchir Gupta is a board-certified pain specialist and anesthesiologist with advanced training in chronic pain management from the Mayo Clinic's Alix School of Medicine in Arizona. A New York native, he completed medical school at Upstate Medical University in Syracuse and his anesthesiology residency at New York Medical College – St. Vincent's Hospital in Manhattan.With over 20 peer-reviewed publications and two medical textbooks to his name, Dr. Gupta blends cutting-edge Western medicine with holistic, nature-based therapies. His areas of expertise include interventional pain management, IV infusion therapy, bone marrow concentrate procedures, and regenerative orthopedics.Dr. Gupta is a member of several leading professional societies, including the American Society of Pain and Neuroscience and the American Headache Society. He currently practices in Mesa and Phoenix, Arizona, where he is also part of the elite Regenexx network of interventional orthopedic physicians.To connect with Dr Gupta:LinkedIn: https://www.linkedin.com/in/ruchir-gupta-3187326b/https://mountainviewheadacheandspine.com/
Dr Sharonne Hayes, Professor of cardiovascular medicine and founding director of Mayo Clinic women's heart clinic, and Dr. Marysia Tweet, Associate Professor of cardiovascular medicine, and co-leader of the Spontaneous Coronary Artery Dissection Registry and leader in women's heart health join the show for this amazing November chapter of Always on EM. They are world experts on Spontaneous Coronary Artery Dissection authoring over 60 peer reviewed articles on the topic and in this chapter we explore with them the pitfalls and pearls related to making this diagnosis in the ED. SCAD is an important cause of myocardial infarction especially in patients who would not otherwise seem to be at risk for heart attacks for example active young women without comorbidities, and its imperitive that we as emergency physicians are current on this diagnosis. DONATE TO DR JIM GREGOIRE SCHOLARSHIP FUND To honor the life of Dr. Jim Gregoire, dear friend of this show, consider donating to his scholarship fund. Go to https://give.mayoclinic.org/give/616870/#!/donation/checkout Go to: What would you like your donation to support? Choose “other” Enter: James Gregoire Scholarship Fund CONTACTS X - @AlwaysOnEM; @VenkBellamkonda; @Marysia_Tweet; @SharonneHayes YouTube - @AlwaysOnEM; @VenkBellamkonda Instagram – @AlwaysOnEM; @Venk_like_vancomycin; @ASFinch; @SharonneHayes Email - AlwaysOnEM@gmail.com DO YOU HAVE SCAD? DOES YOUR PATIENT HAVE SCAD? WANT TO GET CONNECTED? SCAD Research: www.scadresearch.org National Coalition for Women with Heart Disease: www.womenheart.org Mayo Clinic Womens Heart clinic: https://www.mayoclinic.org/departments-centers/womens-heart-clinic/overview/ovc-20442061 REFERENCES & LINKS Saleh G, Al-Abcha A, Chaaban K, Adi MZ, Tweet M, Collins JD, Alkhouli M, Gulati R. Concomitant Takotsubo Cardiomyopathy and Spontaneous Coronary Artery Dissection: Exploring the Role of Cardiac Mechanics on Coronary Disruption. JACC Cardiovasc Imaging. 2025 Oct;18(10):1161-1166. doi: 10.1016/j.jcmg.2025.05.020. Epub 2025 Aug 5. PMID: 40758075. Baqal O, Karikalan SA, Hasabo EA, Tareen H, Futela P, Qasba RK, Shafqat A, Qasba RK, Hayes SN, Tweet MS, El Masry HZ, Lee KS, Shen WK, Sorajja D. In- hospital and long-term outcomes in spontaneous coronary artery dissection with concurrent cardiac arrest: Systematic review and meta-analysis. Heart Rhythm O2. 2025 Apr 24;6(6):843-853. doi: 10.1016/j.hroo.2025.03.023. PMID: 40717849; PMCID: PMC12287955. Morosato M, Gaspardone C, Romagnolo D, Pagnesi M, Baldetti L, Dormio S, Federico F, Scandroglio AM, Chieffo A, Godino C, Margonato A, Adamo M, Metra M, Tchetche D, Dumonteil N, Tweet MS, Saw J, Beneduce A. Left Main Spontaneous Coronary Artery Dissection: Clinical Features, Management, and Outcomes. JACC Cardiovasc Interv. 2025 Apr 28;18(8):975-983. doi: 10.1016/j.jcin.2025.01.427. Epub 2025 Apr 9. PMID: 40208153; PMCID: PMC12290918. Tweet MS, Pellikka PA, Gulati R, Gochanour BR, Barrett-O'Keefe Z, Raphael CE, Best PJM, Hayes SN. Coronary Artery Tortuosity and Spontaneous Coronary Artery Dissection: Association With Echocardiography and Global Longitudinal Strain, Fibromuscular Dysplasia, and Outcomes. J Am Soc Echocardiogr. 2024 May;37(5):518-529. doi: 10.1016/j.echo.2024.02.013. Epub 2024 Mar 11. PMID: 38467311; PMCID: PMC11605948. Tweet MS, Hayes SN, Grimaldo ABG, Rose CH. Pregnancy After Spontaneous Coronary Artery Dissection: Counseling Patients Who Intend Future Pregnancy. JACC Adv. 2023 Dec;2(10):100714. doi: 10.1016/j.jacadv.2023.100714. Epub 2023 Nov 14. PMID: 38915307; PMCID: PMC11194843. Tarabochia AD, Tan NY, Lewis BR, Slusser JP, Hayes SN, Best PJM, Gulati R, Deshmukh AJ, Tweet MS. Association of Spontaneous Coronary Artery Dissection With Atrial Arrhythmias. Am J Cardiol. 2023 Jan 1;186:203-208. doi: 10.1016/j.amjcard.2022.09.032. Epub 2022 Oct 31. PMID: 36328832; PMCID: PMC10403149. Murugiah K, Chen L, Dreyer RP, Bouras G, Safdar B, Lu Y, Spatz ES, Gupta A, Khera R, Ng VG, Bueno H, Tweet MS, Spertus JA, Hayes SN, Lansky A, Krumholz HM. Depression and Perceived Stress After Spontaneous Coronary Artery Dissection and Comparison With Other Acute Myocardial Infarction (the VIRGO Experience). Am J Cardiol. 2022 Jun 15;173:33-38. doi: 10.1016/j.amjcard.2022.03.005. Epub 2022 Mar 29. PMID: 35365290; PMCID: PMC9133198. Johnson AK, Tweet MS, Rouleau SG, Sadosty AT, Hayes SN, Raukar NP. The presentation of spontaneous coronary artery dissection in the emergency department: Signs and symptoms in an unsuspecting population. Acad Emerg Med. 2022 Apr;29(4):423-428. doi: 10.1111/acem.14426. Epub 2021 Dec 26. PMID: 34897898; PMCID: PMC10403148. Murugiah K, Chen L, Dreyer RP, Bouras G, Safdar B, Khera R, Lu Y, Spatz ES, Ng VG, Gupta A, Bueno H, Tweet MS, Spertus JA, Hayes SN, Lansky A, Krumholz HM. Health status outcomes after spontaneous coronary artery dissection and comparison with other acute myocardial infarction: The VIRGO experience. PLoS One. 2022 Mar 23;17(3):e0265624. doi: 10.1371/journal.pone.0265624. PMID: 35320296; PMCID: PMC8942215. Adlam D, Tweet MS, Gulati R, Kotecha D, Rao P, Moss AJ, Hayes SN. Spontaneous Coronary Artery Dissection: Pitfalls of Angiographic Diagnosis and an Approach to Ambiguous Cases. JACC Cardiovasc Interv. 2021 Aug 23;14(16):1743-1756. doi: 10.1016/j.jcin.2021.06.027. PMID: 34412792; PMCID: PMC8383825. Kok SN, Tweet MS. Recurrent spontaneous coronary artery dissection. Expert Rev Cardiovasc Ther. 2021 Mar;19(3):201-210. doi: 10.1080/14779072.2021.1877538. Epub 2021 Feb 26. PMID: 33455483. Campbell KH, Tweet MS. Coronary Disease in Pregnancy: Myocardial Infarction and Spontaneous Coronary Artery Dissection. Clin Obstet Gynecol. 2020 Dec;63(4):852-867. doi: 10.1097/GRF.0000000000000558. PMID: 32701519; PMCID: PMC10767871. Tweet MS, Young KA, Best PJM, Hyun M, Gulati R, Rose CH, Hayes SN. Association of Pregnancy With Recurrence of Spontaneous Coronary Artery Dissection Among Women With Prior Coronary Artery Dissection. JAMA Netw Open. 2020 Sep 1;3(9):e2018170. doi: 10.1001/jamanetworkopen.2020. PMID: 32965500; PMCID: PMC7512056. Hayes SN, Tweet MS, Adlam D, Kim ESH, Gulati R, Price JE, Rose CH. Spontaneous Coronary Artery Dissection: JACC State-of-the-Art Review. J Am Coll Cardiol. 2020 Aug 25;76(8):961-984. doi: 10.1016/j.jacc.2020.05.084. PMID: 32819471. Johnson AK, Hayes SN, Sawchuk C, Johnson MP, Best PJ, Gulati R, Tweet MS. Analysis of Posttraumatic Stress Disorder, Depression, Anxiety, and Resiliency Within the Unique Population of Spontaneous Coronary Artery Dissection Survivors. J Am Heart Assoc. 2020 May 5;9(9):e014372. doi: 10.1161/JAHA.119.014372. Epub 2020 Apr 28. PMID: 32342736; PMCID: PMC7428589. Tweet MS, Akhtar NJ, Hayes SN, Best PJ, Gulati R, Araoz PA. Spontaneous coronary artery dissection: Acute findings on coronary computed tomography angiography. Eur Heart J Acute Cardiovasc Care. 2019 Aug;8(5):467-475. doi: 10.1177/2048872617753799. Epub 2018 Jan 29. PMID: 29376398; PMCID: PMC6027604. Tan NY, Tweet MS. Spontaneous coronary artery dissection: etiology and recurrence. Expert Rev Cardiovasc Ther. 2019 Jul;17(7):497-510. doi: 10.1080/14779072.2019.1635011. Epub 2019 Jul 5. PMID: 31232618. Waterbury TM, Tweet MS, Hayes SN, Eleid MF, Bell MR, Lerman A, Singh M, Best PJM, Lewis BR, Rihal CS, Gersh BJ, Gulati R. Early Natural History of Spontaneous Coronary Artery Dissection. Circ Cardiovasc Interv. 2018 Sep;11(9):e006772. doi: 10.1161/CIRCINTERVENTIONS.118. PMID: 30354594. Hayes SN, Kim ESH, Saw J, Adlam D, Arslanian-Engoren C, Economy KE, Ganesh SK, Gulati R, Lindsay ME, Mieres JH, Naderi S, Shah S, Thaler DE, Tweet MS, Wood MJ; American Heart Association Council on Peripheral Vascular Disease; Council on Clinical Cardiology; Council on Cardiovascular and Stroke Nursing; Council on Genomic and Precision Medicine; and Stroke Council. Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association. Circulation. 2018 May 8;137(19):e523-e557. doi: 10.1161/CIR.0000000000000564. Epub 2018 Feb 22. PMID: 29472380; PMCID: PMC5957087. Tweet MS, Kok SN, Hayes SN. Spontaneous coronary artery dissection in women: What is known and what is yet to be understood. Clin Cardiol. 2018 Feb;41(2):203-210. doi: 10.1002/clc.22909. Epub 2018 Mar 1. PMID: 29493808; PMCID: PMC5953427. Tweet MS, Codsi E, Best PJM, Gulati R, Rose CH, Hayes SN. Menstrual Chest Pain in Women With History of Spontaneous Coronary Artery Dissection. J Am Coll Cardiol. 2017 Oct 31;70(18):2308-2309. doi: 10.1016/j.jacc.2017.08.071. PMID: 29073960; PMCID: PMC5957076. Lindor RA, Tweet MS, Goyal KA, Lohse CM, Gulati R, Hayes SN, Sadosty AT. Emergency Department Presentation of Patients with Spontaneous Coronary Artery Dissection. J Emerg Med. 2017 Mar;52(3):286-291. doi: 10.1016/j.jemermed.2016.09. Epub 2016 Oct 8. PMID: 27727035. Tweet MS, Gulati R, Williamson EE, Vrtiska TJ, Hayes SN. Multimodality Imaging for Spontaneous Coronary Artery Dissection in Women. JACC Cardiovasc Imaging. 2016 Apr;9(4):436-50. doi: 10.1016/j.jcmg.2016.01.009. PMID: 27056163. Tweet MS, Gulati R, Hayes SN. What Clinicians Should Know Αbout Spontaneous Coronary Artery Dissection. Mayo Clin Proc. 2015 Aug;90(8):1125-30. doi: 10.1016/j.mayocp.2015.05.010. PMID: 26250728. Prasad M, Tweet MS, Hayes SN, Leng S, Liang JJ, Eleid MF, Gulati R, Vrtiska TJ. Prevalence of extracoronary vascular abnormalities and fibromuscular dysplasia in patients with spontaneous coronary artery dissection. Am J Cardiol. 2015 Jun 15;115(12):1672-7. doi: 10.1016/j.amjcard.2015.03.011. Epub 2015 Mar 23. PMID: 25929580. Goel K, Tweet M, Olson TM, Maleszewski JJ, Gulati R, Hayes SN. Familial spontaneous coronary artery dissection: evidence for genetic susceptibility. JAMA Intern Med. 2015 May;175(5):821-6. doi: 10.1001/jamainternmed.2014. PMID: 25798899. Liang JJ, Prasad M, Tweet MS, Hayes SN, Gulati R, Breen JF, Leng S, Vrtiska TJ. A novel application of CT angiography to detect extracoronary vascular abnormalities in patients with spontaneous coronary artery dissection. J Cardiovasc Comput Tomogr. 2014 May-Jun;8(3):189-97. doi: 10.1016/j.jcct.2014.02.001. Epub 2014 Apr 4. PMID: 24939067. Tweet MS, Hayes SN, Pitta SR, Simari RD, Lerman A, Lennon RJ, Gersh BJ, Khambatta S, Best PJ, Rihal CS, Gulati R. Clinical features, management, and prognosis of spontaneous coronary artery dissection. Circulation. 2012 Jul 31;126(5):579-88. doi: 10.1161/CIRCULATIONAHA.112. Epub 2012 Jul 16. PMID: 22800851. Tweet MS, Gulati R, Aase LA, Hayes SN. Spontaneous coronary artery dissection: a disease-specific, social networking community-initiated study. Mayo Clin Proc. 2011 Sep;86(9):845-50. doi: 10.4065/mcp.2011.0312. PMID: 21878595; PMCID: PMC3257995. WANT TO WORK AT MAYO? EM Physicians: https://jobs.mayoclinic.org/emergencymedicine EM NP PAs: https://jobs.mayoclinic.org/em-nppa-jobs Nursing/Techs/PAC: https://jobs.mayoclinic.org/Nursing-Emergency-Medicine EMTs/Paramedics: https://jobs.mayoclinic.org/ambulanceservice All groups above combined into one link: https://jobs.mayoclinic.org/EM-Jobs
Confused About Hormones or HRT? Dr. Nicole Lovat Helps You Navigate Midlife Health with Confidence and Clarity Midlife health is not one-size-fits-all — and “normal” doesn't always mean optimal. When you understand your hormones, you can advocate for care that helps you feel your best — inside and out.
Send us a textOn this episode, we interview Dr. Wigdan Farah, a pulmonologist in Mayo Clinic's Division of Pulmonary & Critical Care Medicine to discuss several respiratory conditions seen commonly in pilots seeking medical certification -- then review aeromedical implications and requirements.
Host: Darryl S. Chutka, M.D. Guest: Daniel M. Frendl, M.D., Ph.D. Prostate cancer is quite common in middle age and older men and represents the second most common malignancy diagnosed in this population. Only skin cancer is more common. Early diagnosis is important and carries an excellent prognosis. There are several management options available for localized disease and some new treatments which can be used for both aggressive and more advanced disease. When should active surveillance be used when prostate cancer has been diagnosed? How does radiation therapy compare to surgical prostatectomy regarding long-term outcomes and what are some of the newer treatment options available for advanced disease? These are some of the questions I'll be asking my guest, Daniel M. Frendl, M.D., Ph.D., a urologist from the Department of Urology at the Arizona campus of the Mayo Clinic as we discuss “Prostate Cancer”. Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts
Before leading Mayo Clinic's digital transformation, John D. Halamka, MD, MA was a teenage engineer scavenging defense-contractor dumpsters for computer parts and a Stanford student who helped prototype early multimedia networks long before the internet entered everyday life. In this episode, he sits down with host Geoffrey Rubin, MD, MBA, FACR to trace his remarkable journey across emergency medicine, Silicon Valley entrepreneurship, and national health IT policy. Along the way, he built one of the first web-based electronic health records, helped shape interoperability standards that enable modern data exchange, and pioneered federated analytics (empowering global health systems to collaborate on AI development while keeping patient data local and protected ) and digital care models now being adopted around the globe. Dr. Halamka reflects on the mentors, risks, and resilience that propelled his career, and shares how adaptability, curiosity, and a simple mantra – “All will be well” - continue to guide his leadership philosophy in a rapidly evolving healthcare landscape. Behind the Mic: Dr. John Halamka is an alpinist (a mountain climber who specializes in difficult and challenging ascents, often involving mixed terrain), rock and ice climber. He and his wife also share a deep love for animals and run Unity Farm Sanctuary (unityfarmsanctuary.org) which provides lifetime care for farm animals in need. Located in Sherborn, Massachusetts, Unity Farm Sanctuary is currently home to 400 large animals including gentle giant Dudley the Scottish Highland Bull, affectionate Marky Goat, shy Gypsy Minihorse, and social butterflies Turnip Turkey and Blackbeard Rooster.
Host Lisa Salberg talks with Mayo Clinic's Dr. Steve Ommen about how new therapies, technologies, and guidelines are transforming care for people with hypertrophic cardiomyopathy. They explore what these changes mean for patients, the importance of specialized care, and how collaboration continues to drive progress in the HCM community. Conversation recorded 10/24/25.
Hurricane Melissa tore through Jamaica on Tuesday with winds topping 200 mph. Early Wednesday it made landfall again, this time in Cuba. CBS News' Jason Allen reports. Matthew Samuda, Jamaica's Minister of Water, Environment and Climate Change, joins "CBS Mornings" to talk about the assessing the devastating impact of Hurricane Melissa after it pummeled the island and what's next. There could be a crackdown soon on a type of sports gambling known as prop betting. Instead of picking winners or losers, you bet on something specific that will or won't happen during a game. Now, some pro leagues are discussing limiting prop bets and some states could make it illegal. A new Mayo Clinic study reveals that while most women experience menopause symptoms, more than 80% never seek medical care. In "Facing Fertility," Nikki Battiste reports on a misunderstood treatment that's helping many find relief. Actor and comedian Tracy Morgan joins "CBS Mornings" to discuss his new series, "Crutch," a spin-off of the CBS hit "The Neighborhood." Morgan opens up about playing a Harlem dad, why the role feels personal and how comedy has helped him overcome life's toughest challenges. Major Leaguers vote each year to honor their own for achievements on and off the field. MLBPA's 2025 Player of the Year is Seattle Mariners star Cal Raleigh, with Kyle Schwarber, Tarik Skubal, and Paul Skenes also taking top honors. Skenes joins "CBS Mornings" to celebrate the win. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
Host: Darryl S. Chutka, M.D. Guest: Daniel M. Frendl, M.D., Ph.D. If your practice includes middle age and older men, you've very likely diagnosed prostate cancer. It's the most diagnosed non-skin cancer in men in the U.S. Its incidence rises with age, with a median age of around 66 years. When found early, prostate cancer is very treatable, and in most cases, curable. Prostate specific antigen, or PSA is very effective in detecting early prostate cancer, but its use has been controversial due to the risk of overdiagnosis and overtreatment. What are the current recommendations for prostate cancer screening with PSA? What's the role of the digital rectal exam? How should we be using the PSA and what other tests are available for prostate cancer screening? The topic for this podcast is “Prostate Cancer Screening” and I'll be asking these questions to my guest, Daniel M. Frendl, M.D., Ph.D., a urologist at the Arizona campus of the Mayo Clinic. Tune in this Thursday for our next episode on "Prostate Cancer" releasing October 30, 2025. Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts
What if we reframed our dislike of office politics and saw it instead as a way to help our teams get the recognition they deserve?In complex organizations, politics and strategic networking aren't distractions. They're often the hidden drivers of influence, credibility, and career growth.In this episode of Let's Talk, People, Emily sits down with Audrey Greenberg Venture Partner and Chair of Business Development at Mayo Clinic, to explore how leaders can navigate politics with integrity, build meaningful networks, and advocate for themselves and their teams.Together, they unpack why sponsorship outpaces mentorship, how to “pre-wire the room” before decisions, and what it takes to balance transparency with influence when the stakes are high.Whether you're aiming for a promotion, championing a rising star, or working to break silos, this episode will reshape how you view politics at work and reveal why relationships may be your most powerful leadership tool.Timestamps: [00:08:03] Sponsors, mentors, and visibility - Audrey and Emily unpack why career growth requires mentors (guidance), sponsors (advocacy when you're not in the room), and intentionally created visible moments so your work isn't left to chance.[00:19:29] Negotiating from abundance, not scarcity - Practical negotiation guidance: lead with gratitude, present evidence/benchmarks, ask for shared-success outcomes, and consider levers beyond immediate cash (equity, review cadence, bonus).[00:23:05] Beyond salary: creative levers of recognition - A focused discussion on alternatives to immediate pay increases: equity, title changes, flexibility, PTO, and other levers that can retain and recognize people (and often cost less than cash).[00:31:07] You can be both human and high-performing - Audrey challenges the myth that you have to choose between being human or high-performing, showing how presence and performance actually fuel each other.Access the episode transcript.Join the Conversation: This year we're taking audience questions! Send in your toughest people management and leadership challenges, and we'll anonymize them and tackle them in an upcoming episode. Email Abigail on our Let's Talk, People team with your situation as a written note or voice memo to abigail@arosegroup.com.Connect with Emily Frieze-Kemeny on LinkedIn and Instagram or explore her work through AROSE Group's website.If you'd like to receive new episodes as they're published, please subscribe to Let's Talk, People in Apple Podcasts, Spotify, or wherever you get your podcasts. If you enjoyed this episode, please leave a 5-star rating on Apple Podcasts. It helps others discover the show.Thanks for listening to Let's Talk, People!
When to Consider Intervention for Peripheral Arterial Disease Guest: Stan Henkin, M.D. Host: Malcolm Bell, M.D. Although optimal medical therapy is key to decrease the risk of major adverse cardiac events in patients with peripheral artery disease (PAD), lower extremity arterial revascularization also plays an important role in management of symptoms and prevention of amputation. Thus, it is important to recognize the optimal timing for patient to be referred for lower extremity arterial revascularization. This podcast will discuss when patients with established PAD should be considered for peripheral revascularization. Topics Discussed: Can you tell us about clinical subsets of PAD and what symptoms may be expected with each subset? Recent BEST-CLI trial garnered a lot of attention and press. Can you tell us more about this trial and why results are important for treatment of patients with CLTI? When should a patient with claudication be referred for revascularization? Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode. Podcast episode transcript found here.
What a CreepSeason 31, Episode 2Bill Gothard, founder of the Institute in Basic Life PrinciplesKristen Meinzer from The Nighty on Hatch Plus and Health Matters from the Mayo Clinic joins Sonia Mansfield to talk about creep Bill Gothard, a minister, writer, and the founder of the Institute in Basic Life Principles (IBLP). The IBLP is a fundamentalist Christian organization that encourages the submission of wives to husbands, procreative sex, the corporal punishment of children, homeschooling, and biblical literalism. Those who've escaped it say it goes much further, enlisting coercion, mind control, isolation, sexual abuse, and financial manipulation against its adherents.Sources for this episode:RecoveringGrace.orgQuiverfull: Inside The Christian Patriarchy Movement, by Kathryn JoyceA Well Trained Wife, by Tia LevingsCounting the Cost, by Jill Duggar DillardBecoming Free Indeed, by Jinger Duggar VuoloI Pray You Put This Journal Away, available on SpotifyThe Sojo Files, available on SpotifyLeaving Eden, available on SpotifyShiny Happy People, on Amazon PrimeIBLP.org Chicago Magazine New York Times People magazine Washington Post USA Today The GuardianBuzzFeed NBC News https://inthesetimes.com/article/cult-of-characterThe Sojo Files Leaving Eden Christianity TodayIn Touch WeeklyDuggar Family websiteBe sure to follow us on social media. But don't follow us too closely … don't be a creep about it! Subscribe to us on Apple PodcastsFacebook: Join the private groupBlueSky Instagram @WhatACreepPodcastVisit our Patreon page: https://www.patreon.com/whatacreepEmail: WhatACreepPod@gmail.com We've got merch here! https://whatacreeppodcast.threadless.com/#Our website is www.whatacreeppodcast.com
Rochester is changing in many ways. City blocks are filled with construction work zones. Streets are littered with detours. Cranes tower over the skyline as a massive makeover plays out.Much of it is tied to a major medical expansion associated with the largest employer around — Mayo Clinic. There have also been political shifts. Rochester is one of the shrinking number of places outside of the Twin Cities-area where Democrats seem to have an upper hand. It wasn't always that way.On this special broadcast of Politics Friday, MPR News politics editor Brian Bakst heads to Rochester, where he and his guests talk about what's behind the spruce-up and where the city's politics fit in the southeastern part of the state. Politics Friday in Rochester, Minn. Plus, we'll meet a candidate hoping to make his way to Congress from southern Minnesota. He's an underdog out of the gate. Then, we'll get to know more about Molly Castle Work, the newest MPR News reporter based in Rochester, and a special field production. Later, a politics panel with Dana Ferguson and Catharine Richert. Politics Friday: Voices from Rochester, Minnesota Matt Alvarez, Molly Castle Work, Lukas Levin, and Paton Whaley. On Fridays, MPR News politics editor Brian Bakst discusses Minnesota politics. The show often features a number of voices in a weekly audio postcard.In this special feature, MPR News reporter Molly Castle Work and producer Matt Alvarez ventured out to gauge the economic temperature from Minnesotans in the southeastern part of the state. Guests: Kim Norton is the Mayor of Rochester. She became the first woman to be elected Mayor of Rochester in 2018 after a prior stint in the Legislature. Patrick Seeb is the Destination Medical Center (DMC) Economic Development Agency Executive Director. Sen. Carla Nelson is a Republican representing the southeastern area of the state, now in her fifth term. Jake Johnson is a Democrat running for election to the U.S. House of Representatives for Minnesota's 1st Congressional District. Molly Castle Work is an MPR News reporter based in Rochester. She covers health care in southeast Minnesota. Dana Ferguson is a political correspondent for MPR News. She has covered Minnesota politics and state government for Forum News Service. Catharine Richert is a correspondent based in Rochester, where she covers southeast Minnesota for MPR News. She also leads Talking Sense, a reporting project helping Minnesotans have hard conversations about politics, better. This discussion was recorded at 125 LIVE in Rochester, Minn. on Oct. 21. Use the audio player above to listen to the full conversation or subscribe to the Politics Friday podcast on: Apple Podcasts, Spotify, or RSS.
In this episode, you will learn what to eat to heal your body, starve cancer, and prevent disease - with the food you eat. Today, Mel sits down with Dr. Dawn Mussallem, a double board‑certified Mayo Clinic physician, the first cancer doctor ever on this podcast, integrative oncology pioneer, and stage 4 cancer survivor. Her colleagues at Mayo Clinic call her “the Magic Bullet” because of the incredible results she gets combining traditional medicine with lifestyle interventions. This conversation is going to change the way you think about food, exercise, sleep, stress, and disease. Inside this episode, you'll learn: -The top 5 cancer‑fighting foods -Why the modern diet is making you sick (and why ultra processed foods are a leading cause of death) -Why food is medicine and how it works in your body -The fiber rule tied to lower cancer risk—and why most men miss it -The truth about soy and breast cancer (edamame actually reduces breast cancer recurrence by 25%) -How to make healthy eating unbelievably easy (simple food swaps that heal your body) Whether you want more energy, want to protect your health, or want exact guidance on what to eat and what to avoid for a vibrant life, this episode is for you. What you'll learn today will add years to your life and life to your years, and can do the same for the people you love. And stick around until the end for Dr. Mussallem's powerful personal story - from stage 4 cancer at 26 to a heart transplant five years ago - and the mindset shift that will change how you care for your body. For more resources related to today's episode, click here for the podcast episode page. If you liked the episode, check out this one next: Change Your Body & Your Life in 1 Month: 4 Small Habits That Actually WorkConnect with Mel: Get Mel's newsletter, packed with tools, coaching, and inspiration.Get Mel's #1 bestselling book, The Let Them TheoryWatch the episodes on YouTubeFollow Mel on Instagram The Mel Robbins Podcast InstagramMel's TikTok Subscribe to SiriusXM Podcasts+ to listen to new episodes ad-freeDisclaimer Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Did you know that congenital heart defects (CHDs) affect nearly 40,000 babies born in the United States every year? On this episode, Pediatric Cardiologist Dr. Melissa Lefebvre and medical student Marina Hashim discuss the evaluation and management of common acyanotic congenital heart conditions. Specifically, they will: Review the classification of CHDs as cyanotic versus acyanotic. Discuss the pathophysiology of the three most common acyanotic CHDs – ASD, PDA, and VSD. Describe early clinical findings and use of diagnostic tools. Cover management options, ranging from spontaneous closure to surgical intervention. Explore prognosis and long-term outcomes on physical activity, neurodevelopment, and overall health. Special thanks to Dr. Rebecca Yang and Dr. Abeer Hamdy for peer reviewing this episode. CME available free with sign up: Link Coming Soon! References: Dimopoulos, K., Constantine, A., Clift, P., & Condliffe, R. (2023). Cardiovascular complications of down syndrome: Scoping review and expert consensus. Circulation, 147(5). https://doi.org/10.1161/CIRCULATIONAHA.122.059706 Dugdale, D. C. (Ed.). (n.d.). Pediatric heart surgery - discharge. Mount Sinai. Retrieved April 26, 2024, from https://www.mountsinai.org/health-library/discharge-instructions/pediatric-heart-surgery-discharge Eckerström, F., Nyboe, C., Maagaard, M., Redington, A., & Hjortdal, V. (2023). Survival of patients with congenital ventricular septal defect. European Heart Journal, 44 (1,1), 54-61. https://doi.org/10.1093/eurheartj/ehac618 Heart MRI. (2022, July 24). Cleveland Clinic. Retrieved April 19, 2024, from https://my.clevelandclinic.org/health/diagnostics/21961-heart-mri Leihao, S., Yajiao, L., Yunwu, Z., Yusha, T., Yucheng, C., & Lei, C. (2023). Heart-brain axis: Association of congenital heart abnormality and brain diseases. Frontiers in Cardiovascular Medicine, 10. https://doi.org/10.3389/fcvm.2023.1071820 Meyer, K. (Ed.). (2022, May 1). What is a ventricular septal defect (VSD)? Cincinnati Children's. Retrieved March 12, 2024, from https://www.cincinnatichildrens.org/health/v/vsd Minette, M. S., & Sahn, D. S. (2006). Ventricular septal defects. Circulation, 114(20). https://doi.org/10.1161/CIRCULATIONAHA.106.618124 Mussatto, K. A., Hoffmann, R. G., Hoffman, G. M., Tweddell, J. S., Bear, L., Cao, Y., & Brosig, C. (2014). Risk and prevalence of developmental delay in young children with congenital heart disease. Pediatrics, 133(3), e570–e577. https://doi.org/10.1542/peds.2013-2309 Pruthi, S. (Ed.). (2022, October 21). Ventricular septal defect (VSD). Mayo Clinic. Retrieved April 9, 2024, from https://www.mayoclinic.org/diseases-conditions/ventricular-septal-defect/symptoms-causes/syc-20353495 Right heart catheterization. (2022, July 24). Cleveland Clinic. Retrieved April 19, 2024, from https://my.clevelandclinic.org/health/diagnostics/21045-right-heart-catheterization Shah, S., Mohanty, S., Karande, T., Maheshwari, S., Kulkarni, S., & Saxena, A. (2022). Guidelines for physical activity in children with heart disease. Annals of pediatric cardiology, 15(5-6), 467–488. https://doi.org/10.4103/apc.apc_73_22 Sigmon, E., Kellman, M., Susi, A., Nylund, C., & Oster, M. (2019). Congenital heart disease and Autism: A case-control study. Pediatrics, 144(5). https://doi.org/10.1542/peds.2018-4114 Thacker, D. (Ed.). (2022, January 1). Ventricular septal defect (VSD). Nemours Kids Health. Retrieved April 10, 2024, from https://kidshealth.org/en/parents/vsd.html Tierney, S., & Seda, E. (2020). The benefit of exercise in children with congenital heart disease. Current Opinion in Pediatrics, 32(5), 626-632. https://doi.org/10.1097/MOP.0000000000000942 Ventricular septal defects (VSD). (2021, November 9). Cleveland Clinic. Retrieved April 2, 2024,from https://my.clevelandclinic.org/health/diseases/17615-ventricular-septal-defects-vsd Ventricular septal defect surgery for children. (n.d.). Johns Hopkins Medicine. Retrieved April 11,2024, from https://www.hopkinsmedicine.org/health/treatment-tests-and-therapies/ventricular-septal-defect-surgery-for-children#:~:text=During%20this%20surgery%2C%20a%20surgeon,the%20hole%20between%20the%20ventricles Wernovsky, G., & Licht, D. J. (2016). Neurodevelopmental Outcomes in children with congenital heart disease - what can we impact?. Pediatric Critical Care Medicine: a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 17(8 Suppl 1), S232–S242. https://doi.org/10.1097/PCC.0000000000000800
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to discuss recent news about drug-resistant infections. Later, Paul Jannetto, Ph.D., director of the Clinical and Forensic Toxicology Lab, Clinical Mass Spectrometry Lab, and Metals Lab, joins Dr. Pritt for the deep dive segment. Together, they explore how diagnostics are shaping the future of therapeutics. New podcast format launch (00:25): Drs. Morice and Pritt introduce the exciting new format for “Answers From the Lab,” including the addition of in-depth expert segments. Drug-resistant infections (02:05): Discover how clinical diagnostics play a critical role in combating the growing threat of antibiotic resistance. Diagnostics' role in advancing precision medicine (13:28): Learn how diagnostics, specifically drug monitoring, are advancing personalized therapies and contributing to better outcomes. Note: Information in this post was accurate at the time of its posting. Resources Therapeutics testing: A clear path to accurate answers Therapeutics testing at Mayo Clinic Laboratories WHO warns of widespread resistance to common antibiotics worldwide Tests for infectious disease detection and identification Connect with Us Is there a question or topic you'd like us to explore in a future episode? Email us at mayocliniclabs@mayo.edu. Learn more about our hosts and guests and connect with them on social media. Bobbi Pritt, M.D. Bio | LinkedIn Bill Morice, M.D., Ph.D. Bio | LinkedIn Paul Jannetto, Ph.D. Bio | LinkedIn
Drs. Kavita Vakharia, surgical oncologist from City of Hope, Dr Sara Bateni, surgical oncologist at University of Alabama at Birmingham, Dr Nikhil Khushalanai, medical oncologist at the H. Lee Moffitt Cancer Center and James Jakub, surgical oncologist at the Mayo Clinic, Florida, discuss their current practice regarding multidisciplinary management of melanoma with a focus on the role of adjuvant systemic therapy for stages IIB, IIC and IIIA disease.
The Wellness Connections focus for October 2025 is dedicated to Breast Cancer Awareness resources, which are available free of charge to the community. This month's initiative aims to provide vital information and support for individuals affected by breast cancer, along with their families and caregivers.One of the key resources in this initiative is the involvement of Nurse Navigators. These professionals play a critical role in guiding patients through their cancer journey, offering personalized support and education about treatment options and managing side effects. BREAST CANCER TRAVEL NURSES | TRAVELMARE!Additionally, the Mayo Clinic contributes to this effort by providing valuable information regarding prevention, early detection, and treatment of breast cancer. Explore the link to Andrew Weil's website, which promotes anti-inflammatory diets and lifestyle changes. This resource offers practical advice on adopting these dietary changes, helping individuals make informed choices that support their overall health. October Focus – Breast Cancer Focus | HairBluesHER2..Positive Breast Cancer - What is it?BREAST CANCER AWARENESS & PODCASTS | tech4boomersHER2-positive For older women, free E-Book links that serve as excellent informational tools.Breast Cancer and Older Women | livingsenior.me Lastly, the Westchester Page provides an extensive list of resources, guiding individuals to find additional support services, community programs, and relevant information tailored to their needs. Westchester, NY Senior Connections | livingsenior.meThis October, let's come together to support one another and raise awareness about this important issue.All the best for your well-being! For the past several years, blogging has been both a passion and an avocation. I am engaged in exploring the therapeutic uses of essential oils, and I am also a Climate Advocate. I invite you visit my Website: JudithGuerra.com
Startups from Funding to Community w/ Daniela Santagelo of Freeway - AZ TRT S06 EP15 (277) 8-17-2025 What We Learned This Week: Freeway - Helping Startups - Talent • Capital • Community Talent Retention & Reinvestment are key to building a Flywheel Phoenix Tech Ecosystem is growing, but not yet mature Always need more VC Funding + Deal Flow Government Partnership as enabler for Tech Guest: Daniela Santagelo https://www.linkedin.com/in/danielaalpert/ I'm a founder, startup ecosystem builder, and civic innovation partner working at the intersection of tech, talent, and community. Through my work with Freeway Phx, I help cities, startups, and global partners co-create thriving innovation ecosystems, starting in Arizona and building bridges worldwide. I believe that opportunity doesn't just happen. It's designed. That's why I focus on activating communities, cultivating tech talent, and building connective infrastructure that turns vision into velocity. My journey spans founding multiple companies including scaling a venture-backed startup to $33M in funding and helping grow it to a $100M business. I've also spent 15 years in the Moving & Relocation industry, which gave me a unique lens on talent migration patterns and the infrastructure needed to build resilient, people-first startup communities. Like many founders, I've experienced both the highs of scaling and the lows of setback. That reinvention shaped my sharper mission: helping founders grow and give back. ⚡️ I lead Tech Talent Summits that connect employers, educators, and jobseekers
Send us a textDr. Acosta returns to Causes or Cures to talk about the next big leap in obesity research: using genetics and machine learning to predict which patients will get side effects to popular GLP-1 weight-loss medications like Wegovy and Zepbound. Previously, he was on Causes or Cures to discuss your individual obesity type. He and his team are uncovering why some people experience major weight loss while others face tough side effects—especially nausea. The goal? True precision medicine for obesity: matching the right treatment to the right person before treatment even begins. (You can learn more about their available tests and company here.) Topics We DiscussDr. Acosta's background and what drew him to obesity researchWhy not all obesity is the same—and why that matters for patients and doctorsThe most common questions patients ask about GLP-1 drugs like Wegovy and ZepboundHow big a problem side effects like nausea really are in practiceNew research using genetic markers to predict who's more likely to experience side effectsWhether eating style affects nausea and how Dr. Acosta coaches patients on nutrition while using these medicationsThe possibility of genetic testing before prescribing GLP-1sWhat we know about rarer side effects, from vision to hearing changes, if he thinks more side effects will emergeWhat “satiation” (feeling full) means and why it varies so much between peopleHow genetic risk and satiation scores could determine which obesity treatment works bestDr. Acosta's thoughts on obesity prevention, especially on renewed energy to take on the unhealthy food industryThe persistence of stigma—why “willpower” doesn't tell the whole storyWhether the current obsession with obesity drugs distracts from prevention, nutrition, and community health Listen if you've ever wondered:Why GLP-1 drugs don't work the same for everyoneWhat your genes have to do with weight loss, feeling full and side effectsHow soon doctors could use genetic tests to personalize obesity treatmentWhether prevention is being overshadowed by the pharma spotlightWhy it mattersObesity isn't a one-size-fits-all condition—and neither should its treatment be. Dr. Acosta's research could mark a turning point in how we approach weight loss: scientifically, compassionately, and individually. Dr. Acosta is a Consultant of Gastroenterology and Hepatology at the Mayo Clinic, as well as an Associate Professor of Medicine. His research focus is on gastrointestinal physiology and the complexity of food intake regulation as it relates to obesity. You can learn more about his work here.You can contact Dr. Eeks at bloomingwellness.com.Follow Eeks on Instagram here.Or Facebook here.Or X.On Youtube.Or TikTok.SUBSCRIBE to her WEEKLY newsletter here! (Now featuring interviews with top experts on health you care about!)Support the show
Limb-girdle muscular dystrophies (LGMDs) encompass a group of genetically heterogeneous skeletal muscle disorders. There has been an explosion of newly identified LGMD subtypes in the past decade, and results from preclinical studies and early-stage clinical trials of genetic therapies are promising for future disease-specific treatments. In this episode, Gordon Smith, MD, FAAN, speaks with Teerin Liewluck, MD, FAAN, FANA, author of the article “Limb-Girdle Muscular Dystrophies” in the Continuum® October 2025 Muscle and Neuromuscular Junction Disorders issue. Dr. Smith is a Continuum® Audio interviewer and a professor and chair of neurology at Kenneth and Dianne Wright Distinguished Chair in Clinical and Translational Research at Virginia Commonwealth University in Richmond, Virginia. Dr. Liewluck is a professor of neurology at the Division of Neuromuscular Medicine and Muscle Pathology Laboratory at Mayo Clinic College of Medicine in Rochester, Minnesota. Additional Resources Read the article: Limb-Girdle Muscular Dystrophies Subscribe to Continuum®: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Host: @gordonsmithMD Guest: @TLiewluck Full episode transcript available here Dr Jones: This is Dr Lyell Jones, Editor-in-Chief of Continuum. Thank you for listening to Continuum Audio. Be sure to visit the links in the episode notes for information about earning CME, subscribing to the journal, and exclusive access to interviews not featured on the podcast. Dr Smith: This is Dr Gordon Smith with Continuum Audio. Today I'm interviewing Dr Teerin Liewluck, a good friend of mine at the Mayo Clinic, about his article on the limb girdle muscular dystrophies. This article appears in the October 2025 Continuum issue on muscle and neuromuscular junction disorders, a topic that is near and dear to my heart. Teerin, welcome to the podcast, and maybe you can introduce yourself to our listeners. Dr Liewluck: Thank you very much, Gordon, and I want to say hi to all the Continuum fans. So, I'm Dr Teerin Liewluck, I'm the professor of neurology at Mayo Clinic in Rochester, Minnesota. So, my practice focus on all aspects of muscle diseases, both acquired and genetic myopathies. Glad to be here. Dr Smith: I just had the great pleasure of seeing you at a seminar in Houston where you talked about this topic. And so, I'm really primed for this conversation, which I'm very excited about. I find this topic a little hard, and I'm hoping I can learn more from you. And I wonder if, as we get started, recognizing many of our listeners are not in practices focused purely on muscle disease, maybe you can provide some context about why this is important for folks doing general neurology or even general neuromuscular medicine? Why do they need to know about this? Dr Liewluck: Yes, certainly. So, I would say limb girdle muscular dystrophy probably the most complex category of subgroup of muscle diseases because, by itself, it includes thirty-four different subtypes, and the number's still expanding. So, each subtype is very rare. But if you group together, it really have significant number of patients, and these patients present with proximal weakness, very high CK, and these are common patients that can show up in the neurology clinic. So, I think it's very important even for general neurologists to pick up what subtle clues that may lead to the diagnosis because if we are able to provide correct diagnosis for the patients, that's very important for patient management. Dr Smith: So, I wonder if maybe we can talk a little bit about the phenotype, Terran. I mean, your article does a great job of going over the great diversity. And you know, I think many of us here, you know, limb girdle muscular dystrophy and we think of limb girdle weakness, but the phenotypic spectrum is bananas, right? Rhabdomyolysis, limb girdle distal myopathy. I mean, when should our listeners suspect LGMD? Dr Liewluck: Yes, I think by the definition to all the LGMD patients will have limb girdle of proximal weakness and very high CK. So, these are common phenotypes among thirty-four different subtypes. But if it did take into details, they have some subtle differences. In the article, what I try to simplify all these different subtypes that we can categorize at least half of them into three main group that each group the underlying defect sharing among those subtypes and also translate into similar muscles and extra muscular manifestations. You will learn that some of the limb girdle muscular dystrophy may present with rhabdomyolysis. And we typically think of this as metabolic myopathies. But if you have a rhabdomyolysis patient, the CK remain elevated even after the acute episode, that's the key that we need to think this could be LGMD. That's for an example. Dr Smith: So, I wonder if maybe we can start there. I was going to go in a different direction, but this is a good transition. It's easy to see the opportunity to get confused between LGMD or, in that case, a metabolic myopathy or other acquired myopathies. And I think particularly adult neurologists are more accustomed to seeing acquired muscle disease. Are there particular clues that, or pearls that adult neurologists seeing patients with muscle disease can use to recognize when they should be thinking about LGMD given the diverse phenotype? Dr Liewluck: Yes. What I always tell the patient is that there are more than a hundred different types of muscle diseases, but we can easily divide into groups: acquired and genetic or hereditary. So, the acquired disease is when you encounter the patients who present with acute or subacute cause of the weakness, relatively rapidly progressive. But on the opposite, if you encounter the patient who present with a much more slowly progressive cause of weakness over several months or years, you may need to think about genetic disease of the muscle with also including limb-girdle muscular dystrophy. The detailed exam to be able to distinguish between each type of muscular dystrophy. For example, if proximal weakness, certainly limb girdle muscular dystrophy. If a patient has facial weakness, scapular winking, so you would think about facial scapular hematoma dystrophy. So, the slowly progressive cause of weakness, proximal pattern of weakness, CK elevation, should be the point when you think about LGMD. Dr Smith: So, I have a question about diagnostic evaluation. I had a meeting with one of my colleagues, Qihua Fan, who's a great peripheral nerve expert, who also does neuromuscular pathology. And we were talking about how the pathology field has changed so much over the last ten years, and we're doing obviously fewer muscle biopsies. Our way of diagnosing them has changed a lot with the evolution of genetic testing. What's your diagnostic approach? Do you go right to genetic testing? Do you do targeted testing based on phenotype? What words of wisdom do you have there? Dr Liewluck: Yes, so, I mean, being a muscle pathologist myself, it is fair to say that the utility of muscle biopsies when you encounter a patient with suspects that limb girdle muscular dystrophy have reduced over the year. For example, we used to have like fifteen, seventeen hundred muscle biopsies a year; now we do only thirteen hundred biopsies a year. Yes, as you pointed out, the first step in my practice if I suspect LGMD is to go with genetic testing. And I would prefer the last gene panel that not only include the LGMD, but also include all other genetic muscle disease as well as the conjunctive myopic syndrome, because the phenotype can be somehow difficult to distinguish in certain patients. Dr Smith: So, do you ever get a muscle biopsy, Teerin? I mean you obviously do; only thirteen hundred. Holy cow, that's a lot. So, let me reframe my question. When do you get a muscle biopsy in these patients? Dr Liewluck: Muscle biopsy still is present in LGMD patients, it's just we don't use it at the first-tier diagnostic test anymore. So, we typically do it in selected cases after the genetic testing in those that came back inconclusive. As you know, you may run into the variant of unknown significance. You may use the muscle biopsy to see, is there any histopathology or abnormal protein Western blot that may further support the heterogenicity of the VUS. So, we still do it, but it typically comes after genetic testing and only in the selected cases that have inconclusive results or negative genetic testing. Dr Smith: I'd like to ask a question regarding serologic testing for autoantibodies. I refer to a really great case in your article. There are several of them, but this is a patient, a FKRP patient, who was originally thought to have dermatomyositis based on a low-titer ME2 antibody. You guys figured out the correct diagnosis. We send a lot of antibody panels out. Wonder if you have any wisdom, pearls, pitfalls, for how to interpret antibody tests in patients with chronic myopathies? We send a lot of them. And that's the sort of population where we need to be thinking about limb-girdle muscular dystrophies. It's a great case for those, which I hope is everyone who read your article in detail. What do you have to say about that? Dr Liewluck: Yes, so myositis antibodies, we already revolutionized a few of muscle diseases. I recall when I finished my fellowship thirteen years ago, so we don't really have much muscle myositis antibodies to check. But now the panel is expanded. But again, the antibodies alone cannot lead to diagnosis. You need to go back to your clinical. You need to make sure the clinical antibodies findings are matched. For example, if the key that- if the myocytes specific antibodies present only at the low positive title, it's more often to be false positive. So, you need to look carefully back in the patient, the group of phenotypes, and when in doubt we need to do muscle biopsies. Now on the opposite end, the other group of the antibody is the one for necrotizing autoimmune myopathy; or, the other name, immune-mediated necrotizing myopathy. This is the new group that we have learned only just recently that some patients may present as a typical presentation. I mean, when even thinking about the whole testing autoimmune myopathy, we think about those that present with some acute rapidly progressive weakness, maybe has history of sudden exposures. But we have some patients that present with very slowly progressive weakness like muscular dystrophies. So now in my practice, if I encounter a patient I suspect LGMD, in addition to doing genetic testing for LGMD, I also test for necrotizing doing with myopathy antibodies at the same time. And we typically get antibody back within what, a week or two, but projected testing would take a few months. Dr Smith: Yeah. And I guess maybe you could talk a little bit about pitfalls and interpretation of genetic tests, right? I think you have another case in your article, and I've certainly seen this, where a patient is misdiagnosed as having a genetic myopathy, LGMD, based on, let's say, just a misinterpretation of the genetic testing, right? So, I think we need to think of it on both sides. And I like the fact that the clinical aspects of diagnosis really are first and foremost most important. But maybe you can talk about wisdom in terms of interpretation of the genetic panel? Dr Liewluck:Yes. So genetic testing, I think, is a complex issue, particularly for interpretation. And if you're not familiar with this, it's probably best to have your colleagues in genetics that help looking at this together. So, I think the common scenario we encounter is that in those dystrophies that are autosomal recessive, so we expect that the patient needs to have two abnormal copies of the genes to cause the disease. And if patients have only one abnormal copy, they are just a carrier. And commonly we see patients refer to us as much as dystrophy is by having only one abnormal copy. If they are a carrier, they should not have the weakness from that gene abnormality. So, this would be the principle that we really need to adhere. And if you run into those cases, then maybe you need to broaden your differential diagnosis. Dr Smith: I want to go back to the clinical phenomenology, and I've got a admission to make to you, Teerin. And I find it really hard to keep track of these disorders at, you know, thirty-four and climbing a lot of overlap, and it's hard to remember them. And I'm glad that I'm now going to have a Continuum article I can go to and look at the really great tables to sort things out. I'm curious whether you have all these top of mind? Do you have to look at the table too? And how should people who are seeing these patients organize their thoughts about it? I mean, is it important that you memorize all thirty-four plus disorders? How can you group them? What's your overall approach to that? Dr Liewluck: I need to admit that I've not memorize all twenty-four different subtypes, but I think what I triy to do even in my real-life practice is group it all together if you can. For example, I think that the biggest group of these LGMD is what we call alpha-dystroglycanopathies. So, this include already ten different subtypes of recessive LGMD. So alpha-dystroglycan is the core of the dystrophin-associated glycoprotein complex. And it's heavy glycosylated protein. So, the effect in ten different genes can affect the glycosylation or the process of adding sugar chain to this alpha-dystroglycan. And they have similar features in terms of the phenotype. They present with proximal weakness, calf pseudohypertrophy, very high CK, some may have recurrent rhabdomyolysis, and cardiac and rhythmic involvement are very common. This is one major group. Now the second group is the limb-girdle muscular dystrophy due to defective membrane repair, which includes two subtypes is the different and on dopamine five. The common feature in this group is that the weakness can be asymmetric and despite proximal weakness, they can have calf atrophy. On muscle biopsy sometimes you can see a myeloid on the muscle tissues. And the third group is the sarcoglycanopathy, which includes four different subtypes, and the presentation can look like we share. For the rest, sometimes go back to the table. Dr Smith: Thank you for that. And it prompts another question that I always wonder about. Do you have any theories about why such variability in the muscle groups that are involved? I mean, you just brought up dystroglycanopathy, for instance, as something that can cause a very distal predominant myopathy; others do not. Do we at this point now have an understanding given the better genetics that we have on this and work going on in therapeutic development, which I want to get to in a minute, that provides any insight why certain muscle groups are more affected? Dr Liewluck: Very good question, Gordon. And I would say the first question that led me interested in muscle disease---and this happened probably back in 2000 when I just finished medical school---is why, why, why? Why does muscle disease tend to affect proximal muscles? I thought by now, twenty-five years later, we'd have the answer. I don't. I think this, you don't know clearly why muscle diseases, some affect proximal, some affect distal. But the hypothesis is, and probably my personal hypothesis is, that maybe certain proteins may express more in certain muscles and that may affect different phenotypes. But, I mean, dysferlin has very good examples that can confuse us because some patients present with distal weakness, some patients present with proximal weakness, that's by the same gene defect. And in this patient, when we look at the MRI in detail, actually the patterns of fatty replacements in muscle are the same. Even patient who present clinically as a proximal or distal weakness, the imaging studies show the same finding. Bottom line, we don't know. Dr Smith: Yeah, who knew it could be so complex? Teerin, you brought up a really great point that I wanted to ask about, which is muscle MRI scan, right? We're now seeing studies that are doing very broad MR imaging. Do you use some muscle MRI very frequently in your clinical evaluation of these patients? And if so, how? Dr Liewluck: Maybe I don't use it as much as I could, but the most common scenario I use in this setting is when I have the genetic testing come back with the VUS. So, we look at each VUS, each gene in detail. And if anything is suspicious, what I do typically go back to the literature to see if that gene defect in particular has any common pattern of muscle involvement on the MRI. And if there is, I use MRI as one of the two to try to see if I can escalate the pathogenicity of that VUS. Dr Smith: And a VUS is a “Variant of Unknown Significance,” for our listeners. I'm proud that I remember that as a geneticist. These are exciting times in neurology in general, but particularly in an inherited muscle disease. And we're seeing a lot of therapeutic development, a lot going on in Duchenne now. What's the latest in terms of disease-modifying therapeutics and gene therapies in LGMD? Dr Liewluck: Yes. So, there are several precritical and early-phase critical trials for gene therapy for the common lymphoma of muscular dystrophies. For example, the sarcoglycanopathies, and they also have some biochemical therapy that arepossible for the LGMD to FKRP. But there are many things that I expect probably will come into the picture broader or later phase of critical tryouts, and hopefully we have something to offer for the patients similar to patients with Duchenne muscular dystrophy. Dr Smith: What haven't we talked about, I mean, holy cow? There's so much in your article. What's one thing we haven't talked about that our listeners need to hear? Dr Liewluck: Good questions. So, I think we covered all, but often we get patients with proximal weakness and high CK, and they all got labeled as having limb-girdlemuscular dystrophy. What I want to stress is that proximal weakness and high CK is a common feature for muscle diseases, so they need to think broad, need to think about all possibilities. Particularly don't want to miss something treatable. Chronic, slowly progressive cause, as I mentioned earlier, we think more about muscle dystrophy, but at the cranial range, we know that rare patients with necrotic autonomyopathy and present with limb good of weakness at a slowly progressive cost. So, make sure you think about these two when suspecting that LGMD patient diabetic testing has come back inconclusive. Dr Smith: Well, that's very helpful. And fortunately, there's several other articles in this issue of Continuum that help people think through this issue more broadly. Teerin, you certainly don't disappoint. I enjoyed listening to you about a month ago, and I enjoyed reading your article a great deal and enjoy talking to you even more. Thank you very much. Dr Liewluck: Thank you very much, Gordon. Dr Smith: Again, today I've been interviewing Dr Teerin Liewluck about his article on limb-girdle muscular dystrophy, which appears in the October 2025 Continuum issue on muscle and neuromuscular junction disorders. Please be sure to check out Continuum Audio episodes for this and other issues. And thanks to our listeners for joining today. Dr Monteith: This is Dr Teshamae Monteith, Associate Editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use the link in the episode notes to learn more and subscribe. AAN members, you can get CME for listening to this interview by completing the evaluation at continpub.com/audioCME. Thank you for listening to Continuum Audio.
Guest: Hannah Patten MSP, CCC-SLPEarn 0.1 ASHA CEU for this episode with Speech Therapy PD: https://www.speechtherapypd.com/courses/brain-injury-and-the-pediatric-slpPediatric brain injuries can happen for many different reasons, and they may affect speech, language, feeding, and even result in dysphagia. For many SLPs, working with children who have a brain injury can feel overwhelming, especially if this is a new population for you.In this episode of First Bite, Michelle Dawson, MS, CCC-SLP, CLC, BCS-S, sits down with Hannah Patten, MSP, CCC-SLP, from the Mayo Clinic. Hannah shares the most common causes of pediatric brain injuries, current evidence-based approaches for evaluation and treatment, and practical interventions that can make a real difference.You will leave with functional resources, new ideas, and the confidence to bring hope and support to these little ones and their families.About the Guest(s): Hannah Patten is a speech-language pathologist at Mayo Clinic in Rochester, Minnesota, working in acute care and as part of the Aerodigestive Clinic. She is involved in research projects examining the relationship between oropharyngeal dysphagia and aspiration-related lung disease. She previously worked at Children's Healthcare of Atlanta in inpatient rehabilitation and completed her clinical fellowship at the Charlie Norwood VA Medical Center. Her clinical interests include dysphagia across the lifespan, dysphagia evaluation and treatment in the ICU, pediatric and neonatal feeding and swallowing dysfunction, and tracheostomy and ventilator dependence.
The New Science of Momentum: How the Best Coaches and Leaders Build a Fire from a Single Spark by Don Yaeger, Bernie Banks, Karen Cyphers https://www.amazon.com/New-Science-Momentum-Coaches-Leaders/dp/1400247136 “This book will help you win in the game of life!” – Dick Vitale, ESPN analyst Learn how to capture—and keep—the awesome power of momentum! Most leaders believe in momentum—a phenomenon that's easy to perceive but difficult to define. Which is why so few have been able to explain how to spark it, sustain it, or steer it to unbridled success. Until now. In this groundbreaking book, bestselling author Don Yaeger and leadership expert Bernie Banks uncover what it takes to turn a single moment into unstoppable momentum. Drawing from eight years of research, over 250 interviews, and thousands of survey responses, they reveal a proven model for building momentum across sports, business, politics, and the military. You'll learn how to: Recognize the early spark of momentum and act on it. Build a culture that sustains momentum over time. Apply a research-backed model used by top leaders. Reignite momentum when it begins to fade. Whether you're leading a team or an entire organization, this book will help you harness momentum in every aspect of an enterprise—from team building to recruitment to communications—and make it last.About the author Don Yaeger is a National Speakers Hall of Fame inductee, 12-time New York Times bestselling author, and host of the top-rated Corporate Competitor Podcast. He is Publisher of Forbes Books, Storyteller in Residence for National Geographic, and a former Associate Editor of Sports Illustrated. Don is known for his work with elite sports and business leaders, coaching organizations on building cultures of Greatness using insights from his study of high-performing teams. Celebrated by thought leaders like John Maxwell and Simon Sinek as a master storyteller, Don has appeared on Oprah, CNN, Fox Business, and Good Morning America. His podcast ranks in the top 5% globally and features guests such as Condoleezza Rice and CEOs from Disney, Delta, and Mayo Clinic. A Ball State Hall of Fame alum, Don lives in Tallahassee with his wife and two children.
Falls are a threat to the health of older adults and can reduce their ability to remain independent. However, falls don't have to be inevitable as you age. You can reduce your chance of falling or help a loved one prevent falls. There are proven ways to reduce and prevent falls, even for older adults. We identify older adults as anyone 65 years and older. Physical changes and health conditions — and sometimes the medications used to treat those conditions — make falls more likely as you age. In fact, falls are a leading cause of injury among older adults. Still, fear of falling doesn't need to rule your life. Instead, consider six simple fall prevention strategies. 1. Make an appointment with your health care provider Start by making an appointment with your health care provider. To assess your risk and discuss fall prevention strategies, your health care provider may want to talk about the following: Your medications. Make a list of your prescription and nonprescription medications and supplements, or bring them with you to the appointment. Your health care provider can review your medications for side effects and interactions that may increase your risk of falling. To help with fall prevention, your health care provider may consider weaning you off medications that make you tired or affect your thinking, such as sedatives, antihistamines and some types of antidepressants. Any previous falls. Write down the details, including when, where and how you fell. Be prepared to discuss instances when you almost fell but were caught by someone or managed to grab hold of something just in time. Details such as these may help your health care provider identify specific fall prevention strategies. Your health conditions. Certain eye and ear disorders may increase your risk of falls. Be prepared to discuss your health conditions and how comfortable you are when you walk — for example, do you feel any dizziness, joint pain, shortness of breath, or numbness in your feet and legs when you walk? Your health care provider may evaluate your muscle strength, balance and walking style (gait) as well. 2. Keep moving Physical activity can go a long way toward fall prevention. With your health care provider's OK, consider activities such as walking, water workouts or tai chi — a gentle exercise that involves slow and graceful dance-like movements. These activities reduce the risk of falls by improving strength, balance, coordination and flexibility. If you avoid physical activity because you're afraid it will make a fall more likely, tell your health care provider. Your provider may recommend carefully monitored exercise programs or refer you to a physical therapist. The physical therapist can create a custom exercise program aimed at improving your balance, flexibility and muscle strength. 3. Wear sensible shoes Consider changing your footwear as part of your fall prevention plan. High heels, floppy slippers and shoes with slick soles can make you slip, stumble and fall. So can walking in your stocking feet. Instead, wear properly fitting, sturdy, flat shoes with nonskid soles. Sensible shoes may also reduce joint pain. 4. Remove home hazards Take a look around your home for potential fall hazards. To make your home safer: Remove boxes, newspapers, electrical cords and phone cords from walkways. Move coffee tables, magazine racks and plant stands from high-traffic areas. Secure loose rugs with double-faced tape, tacks or a slip-resistant backing — or remove loose rugs from your home. Repair loose, wooden floorboards and carpeting right away. Store clothing, dishes, food and other necessities within easy reach. Immediately clean spilled liquids, grease or food. Use nonslip mats in your bathtub or shower. Use a bath seat, which allows you to sit while showering. 5. Light up your living space Keep your home brightly lit to avoid tripping on objects that are hard to see. Also: Place night lights in your bedroom, bathroom and hallways. Place a lamp within reach of your bed in case you need to get up in the middle of the night. Make clear paths to light switches that aren't near room entrances. Consider trading traditional switches for glow-in-the-dark or illuminated switches. Turn on the lights before going up or down stairs. Store flashlights in easy-to-find places in case of power outages. 6. Use assistive devices Your health care provider might recommend using a cane or walker to keep you steady. Other assistive devices can help, too. For example: Handrails for both sides of stairways Nonslip treads for bare-wood steps A raised toilet seat or one with armrests Grab bars for the shower or tub A sturdy plastic seat for the shower or tub — plus a hand-held shower nozzle for bathing while sitting down If necessary, ask your health care provider for a referral to an occupational therapist. An occupational therapist can help you brainstorm other fall prevention strategies. Some solutions are easily installed and relatively inexpensive. Others may require professional help or a larger investment. If you're concerned about the cost, remember that an investment in fall prevention is an investment in your independence. (credits MayoClinic)
Not all pain is visible and not all solutions are obvious, especially in chronic pelvic pain. In this episode of BackTable OBGYN, host Dr. Mark Hoffman welcomes Dr. Aakriti Carrubba, an expert in minimally invasive gynecological surgery and pelvic pain from the Mayo Clinic, to talk through the evaluation and treatment of chronic pelvic pain.---SYNPOSISDr. Carrubba shares her journey from Kentucky to Florida, detailing her extensive training and interest in managing pelvic pain. The discussion covers the evaluation of pelvic pain, the significance of a thorough patient history and systematic pelvic exams, and the role of interdisciplinary approaches, including physical therapy and pain management. Dr. Carrubba emphasizes the importance of addressing central sensitization and chronic pain syndromes, explaining that not all pain can be attributed solely to structural abnormalities. The episode also touches on the integration of advanced AI tools in medical practice to enhance patient documentation and overall care.---TIMESTAMPS00:00 - Introduction01:09 - Dr. Carrubba's Background and Journey03:54 - Fellowship Experience and Pelvic Pain Focus06:44 - Approach to Chronic Pelvic Pain14:04 - Detailed Pelvic Pain Exam Techniques17:14 - Trigger Point Injections and Their Role21:33 - Challenges in Pain Management and Education26:34 - Role of Central Sensitization in Chronic Pelvic Pain29:35 - Approach to Central Sensitization and Screening33:13 - Approaches to Excision Surgery36:04 - Post-Surgery Management and Hormonal Suppression38:19 - Teaching and Training in Pelvic Pain Management41:35 - Pain Rehabilitation Clinic for Central Sensitization44:59 - Teaching Pelvic Pain Anatomy to Trainees48:24 - Advancements in AI for Medical Documentation52:26 - Reflections on Pelvic Pain Training and Education56:00 - Final Thoughts
Starting a new IBS-C treatment can bring a mix of hope and uncertainty. How soon will it work? What if side effects appear? Should you keep going or call your doctor? Host Jacqueline Gaulin sits down with Dr. Brian Lacy, gastroenterologist at Mayo Clinic in Jacksonville, FL, to answer the real questions patients ask when starting treatment. In this episode, we discuss: • What patients can realistically expect in the first days and weeks of treatment • What “feeling better” truly means for each individual • Common challenges and side effects patients may experience • How to stay encouraged and avoid stopping treatment too soon without consulting your doctor Relief takes time—and you're not alone on this journey. This episode is made possible with support from Ardelyx.
Heart Healthy Diet: How to Evaluate Your Patients Guest: Kyla Lara-Breitinger, M.D. Host: Stephen L. Kopecky, M.D. Nutrition counseling plays a vital role in cardiovascular care, and even brief conversations can make a meaningful impact. Rapid dietary screeners offer a practical way to assess how heart healthy a patient's eating pattern is, helping providers initiate valuable discussions. While no single cardioprotective diet stands above the rest, emphasizing reduced intake of ultra-processed foods and ensuring adequate protein—primarily from plant-based sources and lean animal proteins like poultry, fish, and seafood—can support heart health. These dietary priorities become especially important in later life stages, when maintaining lean muscle mass is critical to reducing risks of frailty, morbidity, and mortality. How do you evaluate whether your patient is following a heart healthy dietary pattern? What makes a cardioprotective diet different from other diets? Is there a best diet or go-to-diet that is superior to all? When discussing nutrition with patients, what key advice should you prioritize? Easily check your diet with mini-eat.org as discussed by Dr. Lara-Breitinger and Dr. Kopecky! Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode. Podcast episode transcript found here.
Dr. Will Cole sits down with Alisa Lask, founder of Plated Skin Science, to explore how regenerative medicine and beauty collide through the power of exosomes. They unpack the science behind platelet-derived exosomes, why they outperform PRP and stem cells, and how they're redefining skincare from the inside out. Alyssa shares the accidental Mayo Clinic discovery that launched Plated, plus how to apply exosomes correctly for maximum results. They also dive into the new Plated Hair Serum clinical data, the rise of counterfeit beauty products online, and the exciting future of FDA-approved exosome therapies. For all links mentioned in this episode, visit www.drwillcole.com/podcast.Follow us on Instagram @platedskinscience or visit our website www.platedskinscience.com!Sponsors:Follow us on Instagram @platedskinscience or visit our website www.platedskinscience.com!Eat smart at FactorMeals.com/willcole50off and use code willcole50off to get 50% off your first box, plus Free Breakfast for 1 Year. Offer only valid for new Factor customers with code and qualifying auto-renewing subscription purchase.Sign up for your one-dollar-per-month trial and start selling today at SHOPIFY.COM/willcole.Get 20% off, or if you choose the already discounted subscription, you get almost a third off the price! Go now to get this amazing discount: PUORI.com/WILLCOLE.MANUKORA.com/WILLCOLE to save 31% plus $25 worth of free gifts.Go to drinkag1.com/willcole to get a FREE Frother with your first purchase of AGZ!Produced by Dear Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this powerful episode, I was joined by the incredible Dr. George Grant, founder of the Academy of Wellness.
In this inspiring episode of Finding Financial Freedom, host Dr. Disha Spath sits down with Dr. Elaine Stageberg, co-owner and principal of Black Swan Real Estate, to explore how she turned one rental property into a half-billion-dollar real estate empire—all while raising five kids and maintaining a career in psychiatry. Dr. Elaine's journey from a difficult childhood marked by financial instability to becoming a leading real estate investor is a testament to resilience, intention, and the power of mindset. Together with her husband, she built Black Swan Real Estate, a diversified portfolio with over 2,000 doors and nearly $500 million in assets. Tune in as Dr. Elaine shares how she overcame scarcity thinking, leaned into fear, and built financial freedom through strategic investing. Key Topics Covered: 1. Overcoming Adversity and Finding Purpose Elaine's early life shaped by financial scarcity and addiction in her family. The role of love and stability in the midst of chaos—and how it formed her values today. 2. From Medicine to Mindset Why Elaine chose psychiatry and how her background influenced her specialty. The importance of paying it forward and mentoring others. 3. The Accidental Landlord Story How an underwater mortgage led Elaine and Nick to rent out their first home. What she learned about property management, cash flow, and providing housing. Discovering the joy and purpose of real estate beyond spreadsheets. 4. Building Black Swan Real Estate Their first intentional investment: turning a vacant, foreclosed home into a thriving rental. The philosophy behind building value and creating “sacred work” through housing. 5. Mindset, Marriage, and Money Why Elaine says there's never a “perfect time” to start investing—only the courage to begin. How facing fear and uncertainty became their superpower for growth. 6. Introducing the Secure Freedom Fund How investors can partner with Black Swan Real Estate through the Secure Freedom Fund. Earn a 10% fixed rate of return through institutional-quality real estate investments. Listener Takeaways: Lean into fear—growth happens outside your comfort zone. Real estate can be sacred work that provides both purpose and profit. Adversity can be a foundation for resilience and success. Start before you're ready—there's never a perfect time to invest. Financial freedom is not just about money but about designing life on your terms. Resources Mentioned: Black Swan Real Estate Secure Freedom Fund Connect with Us: Host: Dr. Disha Spath, The Frugal Physician Guest: Dr. Elaine Stageberg – Co-Owner & Principal, Black Swan Real Estate This episode is brought to you by Black Swan Real Estate, led by physician-investor Dr. Elaine Stageberg. Dr. Stageberg, a Mayo Clinic–trained physician, together with her husband Nick, has spent years building Black Swan Real Estate into a diversified, large-scale portfolio now approaching half a billion dollars across 2,000 doors. Now, through their Secure Freedom Fund, a 10% fixed rate of return offering, you can invest alongside them. The Secure Freedom Fund offers institutional-quality real estate opportunities—designed to deliver strong cash flow, long-term growth, and remarkable tax advantages. This fund is uniquely structured so that each investor can tailor it to their own individual goals: a minimum investment of just $25,000, the ability to choose monthly cashflow distributions or to elect the compounding option for higher overall growth, the option to exit the fund on your timing, the flexibility to invest in your personal name, a trust, an LLC, or a retirement account, and so much more. If you're an accredited investor who's ready to diversify beyond Wall Street and invest with experienced, trust worthy operators who've been exactly where you are, visit SecureFreedomFund.com today to learn more. From there, you can review the slides, watch the webinar, and even a book a call directly 1:1 with Dr. Elaine Stageberg. That's SecureFreedomFund.com.
Published October 16, 2025 In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, and William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, discuss recent regulatory and policy developments. Together, they explore:FDA rescinds rule on LDTs (00:48): The FDA has officially withdrawn its rule that would allow oversight of laboratory-developed tests (LDTs) as medical devices. The conversation explores what this decision means and what might come next for LDT regulation.PAMA reform update and new RESULTS Act (05:13): The newly introduced Reforming and Enhancing Sustainable Updates to Laboratory Testing Services (RESULTS) Act aims to address reimbursement for laboratory tests.Getting engaged (12:37): Why it is important to understand new regulatory policies and help others understand their implications for the industry.ResourcesFind past “Answers From the Lab” podcasts on LDTs and PAMA
We're celebrating something BIG today… Episode 180 of Organizing with Ease! When I first started this podcast, it was co-hosted — just two women, two mics, and a lot of coffee. Then life shifted, and I had to decide: stop or keep going solo. And I chose to keep going, little by little. Week after week, step by step, here we are — 180 episodes later. And that's exactly what this milestone episode is all about: how to keep making progress when life feels full. Because let's be honest — October is busy. School, sports, deadlines, and holidays creeping closer. And the temptation is to say, “I'll wait for the perfect time.” But as research, real-life stories, and even some funny sayings remind us — progress doesn't come from giant leaps. It comes from small, consistent steps. In this episode, you'll learn: Why small, daily actions matter more than rare, giant efforts. What the Harvard Business Review and Stanford research say about the power of “little by little.” Why the Mayo Clinic believes daily low-intensity actions reduce stress better than bursts of effort. Client stories about garages, photos, and yes… even junk drawers, all transformed in just minutes a day. The quotes that keep me grounded, like: “A year from now, you'll wish you had started today.” – Karen Lamb “Great things are not done by impulse, but by a series of small things brought together.” – Vincent Van Gogh “Autumn shows us how beautiful it is to let things go.” – Unknown By the end of this episode, you'll be ready to identify one area in your home or life to tackle in just 10 minutes a day — and you'll see how powerful that can be. ✨ Your October Challenge Calendar To make this fun and doable, I've created a free October Challenge Calendar you can download right now. It's filled with simple, daily prompts to help you stay consistent this season. Print it, post it where you'll see it, and check it off little by little. ➡️ [Download your October Challenge Calendar here] Support the showConnect with Diana:Business email: Diana@dsdeclutrr.comOur Instagram: @dsdeclutrrOur Facebook: @dsdeclutrrOur Websites: dsdeclutrr.com
Things are getting wooshy this week — maybe it's Brandi's post-blood-draw haze or Wells' weed drink enlightenment — but either way, YFT is straight-up floatin y'all. Exhibit A: Wells clocked a full nine hours and seventeen minutes of sleep with a resting heart rate low enough to qualify him for a Mayo Clinic newsletter (he swears he's fine). From there, your hosts spin into why billionaires only ever seem to climb Everest or start space programs, why Mallworld might be the greatest shared fever dream of our generation, and why today's kids simply need to go out and party more.Fave things this week include medieval dragons, true hauntings, dancing stars and missing cons, plus some wildly passionate listener voicemails to round it all out. Buckle up, YFT fam — we're wooshin'.Thanks to our awesome sponsors for supporting this episode! Mood: Get 20% off your first order at Mood.com/YFT with promo code YFT.Hungryroot: For a limited time get 40% off your first box PLUS get a free item in every box for life. Go to Hungryroot.com/yft and use code yft.Quince: Treat your closet to a little summer glow-up with Quince. Go to Quince.com/yft for free shipping on your order and 365 day returns.Cowboy Colostrum: For a limited time, our listeners are getting 25% off their entire order. Just head to CowboyColostrum.com and use code YFT at checkout.Fabletics: Treat yourself to gear that looks good, feels good, and doesn't break the bank with Fabletics. Go to Fabletics.com/YFT and sign up as a VIP and get eighty percent off everything.Draft Kings: New players get FIVE HUNDRED SPINS over TEN DAYS on your choice of Cash Eruption slots when you wager five dollars. Get the app, sign up with code YFT, then start spinning on THE Home of Cash Eruption.Skims: Shop my favorite bras and underwear at SKIMS.com. After you place your order, be sure to let them know we sent you! Select "podcast" in the survey and be sure to select our show in the dropdown menu that followsDon't forget to rate, review, and follow Your Favorite Podcast! Plus, keep up with us between episodes on our Instagram pages, @yftpodcast @wellsadams and @brandicyrus and be sure to leave us a voicemail with your fave things at 858-630-1856! This podcast is brought to you by Podcast Nation.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this first part of a two-part episode, host David Mandell welcomes Dr. Jack Bert, a board-certified orthopedic surgeon and former president of the Arthroscopy Association of North America. Dr. Bert shares his background, including his training at Northwestern, Temple, and the Mayo Clinic, as well as his career—building one of the first outpatient ambulatory surgery centers in Minnesota. He highlights how his practice expanded from a solo effort into a large multi-location group, providing insight into the evolution of orthopedic practice models. Dr. Bert reflects on the influences that led him to orthopedics, including his brother, a spine surgeon, and his time training with John Lachman. He emphasizes the role of innovation in orthopedic surgery, from pioneering arthroscopic procedures to developing surgical tools and implants. His experiences underscore the importance of adapting to insurance reimbursement models and industry dynamics that affect medical practice and physician compensation. Beyond his clinical and entrepreneurial achievements, Dr. Bert discusses his involvement with industry partners and his tenure on the board of the Retired NFL Players Association, where he saw firsthand the long-term toll professional football takes on players. He also stresses the importance of ancillary services and delegation for physicians to achieve financial success, drawing parallels between leveraging physician extenders in medicine and delegating financial management to professionals. Learn more, including additional show notes, links, and detailed key takeaways, by visiting physicianswealthpodcast.com. Click here to get your FREE copy of our latest book, Wealth Strategies for Today's Physician!
Rich sits down with coach and recovery advocate Jennifer Chase, whose life spans both sides of addiction—as the daughter of an alcoholic, a woman in long-term recovery, and the mother of a recovering addict. She shares how trauma, chronic pain, and over-prescription pulled her into dependency, and how connection, forgiveness, and firm, loving boundaries rebuilt her family. Listeners will learn practical ways families can stop enabling, set clear limits, and find peace—no matter where their loved one is on the recovery path. Sponsored by Living Well Healthcare Guest Bio: Jennifer Chase is an addiction and family recovery coach and founder of Rise Addiction Life Coaching. After surviving a hemorrhaging brain tumor, years of chronic pain, and opioid dependency, she rebuilt her life in long-term recovery and now helps families replace chaos with clarity through coaching groups, retreats, and one-to-one guidance. Main Topics: · Addiction vs. recovery “circles” and why connection saves lives. · Generational trauma: growing up around alcoholism and childhood sexual abuse. · Brain tumor at 29, chronic pain, and how over-prescription led to opioid addiction. · Discovering her teenage son's opioid use and choosing treatment. · Why “substance isn't the problem”—shame, coping, and choosing your hard. · Family roles, enabling vs. allowing consequences, and boundary-setting that sticks. · Self-care for helpers: meditation, exercise, journaling, therapy, service. · Jennifer's services: individual coaching, twice-weekly coaching calls, and retreats. Resources mentioned: · Rise Addiction Life Coaching – www.riseaddictionlc.com (Jennifer's site). · Mayo Clinic (treatment exploration referenced). · Podcasts/people referenced in passing (e.g., “Mr. Whiskey,” “Tanya”) as cross-guest overlap. · Practices: meditation, running/exercise, journaling, massage, yoga/chiropractic, counseling.· Episode Sponsor: Send us a textLiving Well HealthcareGet Your Lifestyle BackDisclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showRate & Review on Apple Podcasts Follow the Conversations with Rich Bennett podcast on Social Media:Facebook – Conversations with Rich Bennett Facebook Group (Join the conversation) – Conversations with Rich Bennett podcast group | FacebookTwitter – Conversations with Rich Bennett Instagram – @conversationswithrichbennettTikTok – CWRB (@conversationsrichbennett) | TikTok Sponsors, Affiliates, and ways we pay the bills:Hosted on BuzzsproutSquadCast Subscribe by Email
Today we have Sue. She is 54 years old from Stewartville, MN and she took her last drink of alcohol on May 9th, 2023. This episode brought to you by: Sober Link sign up and claim your $100 enrollment bonus Next Monday, October 20th, we start our four-week mindfulness course in Café RE. It starts at 7:30pm Eastern and we hope to see you there! [02:36] Thoughts from Paul: Paul shares that while visiting his parents in Colorado, he lost his wallet at a park. Thankfully, a high school friend's mom ended up being the one that found it. When he picked it up from her, she told him that her son is recently sober and gave Paul his phone number to reconnect. Paul had recently tried to rejoin the fantasy football league he had previously been a part of and was denied re-entry. This brought up huge feelings of rejection reminiscent of his childhood. While on a retreat with his sober friend in Mexico, Paul found himself dwelling on the negative emotions when he caught himself looking at a beer a fellow diner was having. The thought that “one or two beers would make you feel better” came over him, but then he looked at his newly sober friend and reflected on the great talks of sobriety that they had shared, and the thoughts went away. Reeling from this, Paul went outside, shook his head a few times and then was filled with a warm embrace by the universe knowing that his lost wallet put him in Mexico with his sober friend and everything ended up alright. [07:36] Paul introduces Sue: Sue is 54 years old and has two adult children and one granddaughter. She works as a housekeeper for a hospital at the Mayo Clinic and for fun she loves nature, animals, hikes, jet skiing, kayaking and birdwatching. Sue's parents were both daily drinkers. Sue would sip her dads beer because she thought it was cool, but her first real drinking experience was when she stole some sloe gin from her parent's pantry at age 13 or 14. In her teenage years she began to party a lot on the weekends. Sue was a shy girl, and drinking helped her open up and gave her the attention she craved. Her grades in school began to suffer because she was skipping a lot and Sue ended up unable to graduate. Sue never thought her drinking was a problem even after getting in trouble for underage drinking. Her boyfriend was abusive, but due to her craving for love and attention, Sue kept going back to him. After a long breakup, he returned wanting to reunite, claiming he had changed. Soon Sue became pregnant, got married, quit drinking and focused on having a family. Sue enjoyed being a mother. Her husband worked a lot, so she did a lot of the parenting on her own while working a full-time job. As the kids got older and were home less, Sue began to drink more. She tried to hide her drinking, but her kids began to notice. Sue and her husband were fighting a lot and eventually had a messy divorce in which her husband got custody, which was very hard on Sue. Sue got remarried in 2015 and while she cut back a little, her husband started calling her out on how often she was drinking. This led to her hiding her drinking again and several hospitalizations over the next few years. In 2017, after a hospitalization, Sue was able to get sober with the help of AA. She says complacency led to relapses. Her children had cut her off and there were multiple inpatient and outpatient attempts but nothing stuck until May 9th, 2023. Sue says the difference this time is that she fully surrendered and is doing this for herself and not others. She checked herself Hazelden and dug into the work of loving herself again. She still stays active with that community and her AA group. Sue says her spirituality comes from nature and her belief in prayer and hope. She has been able to reconnect with her children over the past year and has plans to become a peer recovery specialist. Recovery Elevator Go big, because eventually we all go home. I love you guys. RE on Instagram Recovery Elevator YouTube Sobriety Tracker iTunes
Bill George is a celebrated leader who served as Chair and CEO of Medtronic, the world's leading medical technology company. He is an executive fellow at Harvard Business School, where he has taught leadership since 2004, and is the bestselling author of many books, including Discover Your True North. Bill also served as a director at Goldman Sachs, ExxonMobil, Novartis, Target, the Mayo Clinic, and World Economic Forum USA. In this episode of the Elevate Podcast, Bill joins host Robert Glazer to discuss his leadership career, the importance of purpose-driven leadership, and more. To learn more about core values, check out The Compass Within. Thank you to the sponsors of The Elevate Podcast Mizzen & Main: mizzenandmain.com (Promo Code: elevate20) Shopify: shopify.com/elevate Indeed: indeed.com/elevate Masterclass: masterclass.com/elevate Found: found.com/elevate Learn more about your ad choices. Visit megaphone.fm/adchoices