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Join Callum and Jame, two infectious diseases doctors, as they discuss everything you need to know to diagnose and treat infections. Aimed at doctors and clinical staff working in the UK. Queries, comments, suggestions to idiotspodcasting@gmail.com

Infectious Disease: Insights of Two Specialists

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    • May 26, 2025 LATEST EPISODE
    • every other week NEW EPISODES
    • 36m AVG DURATION
    • 110 EPISODES


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    Latest episodes from ID:IOTS

    110. The yeasts: Candida part 3, C. auris and Candida resistance

    Play Episode Listen Later May 26, 2025 56:16 Transcription Available


    The conclusion of the Candida trilogy focuses on the rise of the Lord of the Candida resistance mechanisms: C. auris.Alyssa and Callum are joined by returning guest Professor Tihana Bicanic to discuss the rise of C. auris. Here we highlight some resources for managing this difficult to treat Candida including the recent UKHSA updated guidelines. We also discuss anti-fungal resistance mechanisms in Candida in general.Although this concludes the Candidal section, there are more yeasts yet to come!Show notes for this episode here: https://idiots.notion.site/108-110-Yeasts-Candida-0eb5f9271f654312b59458d39f8de603?pvs=74 Send us a text Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    109. The yeasts: Candida part 2, Candidaemia and invasive disease

    Play Episode Listen Later May 19, 2025 44:46 Transcription Available


    Yes we've done a Candida episode, but what about SECOND Candida episode?This week in the second part of the Candida Trilogy Alyssa and Callum are joined by Professor Tihana Bicanic to discuss all things invasive Candidiasis.Listen in to hear about treatment and diagnosis of this important condition, as well as some areas of current research and the most recent guidelines from ECMM-ISHAM. (Note this episode was recorded before they were released).Show notes for this episode here: https://idiots.notion.site/108-110-Yeasts-Candida-0eb5f9271f654312b59458d39f8de603?pvs=74 Send us a textSupport the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    108. The yeasts: Candida part 1, overview and superficial candidiasis

    Play Episode Listen Later May 12, 2025 45:13 Transcription Available


    In this episode there will be puns where you yeast expect them...But more seriously, what does Candida albicans actually mean? What are yeasts anyway? How does this all relate to the Romans?These questions, and more, will be answered as Alyssa and Callum continue the Fungal series with this, the first in a 3-parter on all things Candida!In this episode we cover the Taxonomy (newly confusing), Epidemiology and Pathogenesis of Candida spp. before talking about superficial candidiasis.Look out for upcoming episodes on invasive Candidiasis and C. auris!Show notes for this episode here: https://idiots.notion.site/108-110-Yeasts-Candida-0eb5f9271f654312b59458d39f8de603?pvs=74 Send us a textSupport the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    107. Staphylococcus aureus bacteraemia (SAB) - interpreting and applying the literature

    Play Episode Listen Later Apr 28, 2025 35:44 Transcription Available


    What exciting times! Clinical trials into the management of SAB! SNAP publication on the horizon! But how do we interpret and apply the results of these trials to our patients? This week Jame and Callum are joined by Dr Clark Russell, Clinical Lecturer in Infectious Diseases to discuss:The difficulty in interpreting current clinical trials in SAB.The emerging concept of "low risk" SAB and how to define this.The heterogeneity of SAB and how this might be exploited.Notes for this episode here: https://idiots.notion.site/107-SAB-update-1316a1ea09d8800ba701ca7ebc8d4093 Previous episodes for the basics of Staphylococcus aureus and SABATO & SNAP trials:1. It starts with Staph65. SNAP trial protocol72. SABATO trial & 73. SABATaddendumSend us a text Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    105. Fungal diagnostics part 2: biomarkers, serology and molecular

    Play Episode Listen Later Apr 14, 2025 45:22 Transcription Available


    Callum and Alyssa are joined by Professor Malcolm Richardson to talk about all things fungal diagnostics.In this, part 1 of 2 on diagnostics we discuss the use of biomarkers such as beta-D-Glucan and galactomannan, as well as serology and molecular techniques.Notes for this episode can be found: here.Send us a textSupport the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    104. Fungal Diagnostics part 1: Microscopy, Culture & Identification techniques

    Play Episode Listen Later Apr 7, 2025 50:39 Transcription Available


    Callum and Alyssa are joined by Professor Malcolm Richardson to talk about all things fungal diagnostics.In this, part 1 of 2 on diagnostics we discuss the use of microscopy, histopathology and culture in diagnosing fungal infections.Notes for this episode can be found: here.Send us a textSupport the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    104. IDSA Difficult To Treat Gram negatives Guidance 2024 with Breakpoints podcast

    Play Episode Listen Later Mar 24, 2025 78:41 Transcription Available


    IT'S A BREAKPOINTS BREAKOUT!Jame and Callum are joined by the drugnamic duo of Julie-Ann Justo & Erin McCreary from the Breakpoints podcast to delve into the IDSA DTR Gram negative Guidance.Show notes for this episode are here.Breakpoints podcast can be found here: https://breakpoints-sidp.org/Lyrics: Tryin' to use some drugs to kill these bugsErin and Julie are PK PD thugs Gonna make these two ID:IOTS look like mugsIt's gonna be a Breakpoints BreakoutSorry the song sounds so tinny, Podcast host is doing something strange to it. Link to original MP3 here. Send us a textSupport the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    103. Fungal infections overview and series intro

    Play Episode Listen Later Mar 17, 2025 31:04 Transcription Available


    My my! Mycology?Join Callum and special co-host Alyssa for this, the first in the all new ID:IOTS Mycology Mega-series.Here we cover:What the British Society of Medical Mycology is and what they do Why we're doing this series on fungi  The Global and UK Burden of fungal disease. The spectrum of fungal disease clinically, The taxonomy of these pathogens, and the WHO Fungal Pathogen List.Notes for this episode can be found here.Send us a textSupport the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    102. AST: When there are NO breakpoints- how to use the EUCAST guidance document

    Play Episode Listen Later Mar 3, 2025 14:50 Transcription Available


    So now, Loyal Listener, you know all about Susceptible, Sensitive at higher doses, Resistant, MICs, ECOFFs/ECVs and how to use the EUCAST breakpoints table....But what about the wild-west of bug-drug combos where there are no breakpoints?Well in this episode, Jame and Callum talk through the EUCAST approach to this situation.Show notes for this episode hereSend us a text Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    101. AST: When there ARE breakpoints - how to use the EUCAST clinical breakpoints table

    Play Episode Listen Later Feb 24, 2025 15:56 Transcription Available


    BREAKPOINTS. We all love them. S breakpoints... R breakpoints... dash, IE, NA... Wait, dash, IA, NA, Brackets?! LISTEN ON (and read the accompanying prep notes), and soon you'll know! In this episode Jame and Callum talk through the EUCAST breakpoints table and how to interpret itShow notes for this episode hereSend us a text Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    100. AST: Rapid Identification and Molecular AST. The BCID2 & Vitek Reveal with BioMérieux

    Play Episode Listen Later Feb 10, 2025 34:49 Transcription Available


    Jame is joined by Kate from BioMérieux as they take a deep dive into the BCID2 and the Vitek Reveal, 2 new devices used for rapid identification and antimicrobial susceptibility testing of blood culture isolates.Note: This episode was produced in collaboration with BioMérieux. An honorarium received from them will be donated directly to charitable causes.Message from BioMérieux: Every effort has been made to ensure the accuracy of information shared during our podcast appearances. The views expressed by our representatives are in good faith and based on the information available at the time. We accept no liability for any errors, omissions, or discrepancies. For the most accurate and up-to-date product details, please refer to our official website or contact us directlySend us a textSupport the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    99. AST: Automated Identification & Sensitivities - the Vitek2 with BioMérieux

    Play Episode Listen Later Jan 27, 2025 26:37 Transcription Available


    This week Jame is joined by Nick and Dal from BioMérieux as they take a deep dive into the Vitek2, one of the machines available for performing Automated Antimicrobial Susceptibility Testing.Note: This episode was produced in collaboration with BioMérieux. An honorarium received from them will be donated directly to charitable causes.Message from BioMérieux: Every effort has been made to ensure the accuracy of information shared during our podcast appearances. The views expressed by our representatives are in good faith and based on the information available at the time. We accept no liability for any errors, omissions, or discrepancies. For the most accurate and up-to-date product details, please refer to our official website or contact us directlySend us a textSupport the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    98. Meningitis

    Play Episode Listen Later Jan 6, 2025 67:20 Transcription Available


    Jame and Callum are joined by Dr Fiona McGill, lead author of the 2016 Joint Specialist Societies Meningitis Guidelines.Listen to hear an overview of the epidemiology, presentation, diagnosis and management of both bacterial and viral meningitis in the UK. Show notes for this episode hereSend us a text Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_pod and Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    97. FIS 2024 part 3: Fungi, NTM, quinolones and others

    Play Episode Listen Later Dec 23, 2024 20:06 Transcription Available


     HO HO HO, MERRY FISMAS!!!On the Third & Final Pod of FISmas these ID:IOTS have for you… 6 golden topics! Listen to hear about:1. Personalised approach to invasive fungal infection2. Agricultural anti-fungals and One Health3. Candida auris4. NTM standards of care5. Narrative reporting 6. Fluoroquinolones and the MHRA warnings Jame and Callum attended the Federation of Infection Societies 2024 annual meeting in  Liverpool; here they share their reflections on the sessions  they attended on:  a wide mix of topicsWe hope these episodes have been ADVENTatious to your learning.Notes for this episode here Send us a text Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    96. FIS 2024 part 2: Viruses

    Play Episode Listen Later Dec 16, 2024 23:13 Transcription Available


    HO HO HO, MERRY FISMAS!!!On the Second Pod of FISmas these ID:IOTS have for you… an all-enveloping, capsidating update on the High Consequence Infectious Diseases, measles, RSV and other viruses that you ‘R naught' going to want to skip! Jame and Callum attended the Federation of Infection Societies 2024 annual meeting in  Liverpool; here they share their reflections on the sessions  they attended on: Viral pathogensFinal episode on fungi etc. coming soon!Notes for this episode hereSend us a text Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    95. FIS 2024 part 1: AMR & Bacteria

    Play Episode Listen Later Dec 9, 2024 28:42 Transcription Available


    HO HO HO, MERRY FISMAS!!!On the First Pod of FISmas these ID:IOTS have to you… a terrifying update on the Antibiotic Apocalypse! Jame and Callum attended the Federation of Infection Societies 2024 annual meeting in  Liverpool; here they share their reflections on the sessions  they attended on: Bacteria and Antimicrobial resistance.Episodes on viruses, fungi etc. coming soon!Notes for this episode hereSend us a text Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    94. BSAC OPAT conference 2024

    Play Episode Listen Later Dec 2, 2024 25:14 Transcription Available


    Jame regales Callum with tales of his online adventure to the BSAC OPAT conference. Listen in to hear some updates on: implementation of OVIVA; subcutaneous antibiotics; and the BSAC OPAT good practice guidelines Notes for this episode here.Send us a text Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    93. World AMR Awareness Week special: The Scottish Antimicrobial Prescribing Group (SAPG)

    Play Episode Listen Later Nov 18, 2024 54:22 Transcription Available


    WAAW! This week, to celebrate World AMR Awareness Week, Callum is Joined by Andrew, Fran, Jo and Simon from the Scottish Antimicrobial Prescribing Group. Listen in to hear all about SAPG and their important work, plus we discuss WAAW and what you can do to help tackle AMR.Show notes for this episode here, including links to the resources mentioned.Sign up to be an #antibioticguardian here.Send us a text Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    92. What is resistance anyway? (S/I/R)

    Play Episode Listen Later Nov 12, 2024 36:25 Transcription Available


    Have you ever looked at your microbiology lab report and wondered "What does resistant mean anyway?" We're sure you have (and if you haven't you should have)! And conveniently we've recorded this podcast episode to explain how it all works! We talk through the definition of S, I & R, plus some explanation on the science behind these letters.Show notes for this episode here.Send us a text Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    91. The ID:IOTS Guide to Tetracyclines 2: Tigecycline, Eravacycline, Omadacycline

    Play Episode Listen Later Oct 28, 2024 38:15 Transcription Available


    They're new, they're weird, and we don't use them very much (or at all), but that won't stop your favourite ID:IOTS sounding off on these novel tetracyclines! In this episode we discuss: An overview of the 3 drugs, including spectrum & penetrance; pharmacokinetics; EUCAST breakpoints; resistance mechanisms; and the recommendations for use in the IDSA DTR Gram Negative guidelines 2024. Prep notes for the episode here. Got a question? Use the new 'send us a text' link in the episode description! Send us a text Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    90. IV to Oral Switch

    Play Episode Listen Later Oct 14, 2024 20:13


    In which Jame talks about the rationale for IVOS, evidence base for the pros and cons, and then finishes by giving the UK oral switch criteria an absolute rinsing. Prep notes available here. Send us a text Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    88. Moraxella catarrhalis: profuse watery discharge

    Play Episode Listen Later Sep 30, 2024 14:57 Transcription Available


    Moraxella means more moronic puns from Jame&Callum. A short episode for some sort rods. Listen to hear about this coccobacillus, how to identify it in the lab and what sort of clinical syndromes it causes.Show note for this episode hereSend us a text Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    88. Where are all the new antibiotics?

    Play Episode Listen Later Sep 13, 2024 23:04 Transcription Available


    Join Jame and Callum as they discuss this paper which examines where these new antibiotics are going, and why they aren't widely available.Notes for this episode hereSend us a text Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    87. ID:IOTS guide to Tetracyclines

    Play Episode Listen Later Aug 30, 2024 28:40 Transcription Available


    Join Jame and Callum on this episode about the  ultimate 4 rings of power: Tetracyclines. The swiss army knife of antibiotics. We talk through the history, uses, mechanism, PK/PD and resistance.Become a pharmacophil as you learn something about pharmacophores.Shows notes for this episode hereSend us a text Support the Show.Questions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    86. Legionella and pontiac fever

    Play Episode Listen Later Aug 23, 2024 35:10 Transcription Available


    Jame and Callum are joined by Lee John and Ella for this episode around the arch-villain of atypical pneumonia and the bogeyman of every spa. Yes Legionella pneumophila (and friends) are addressed in depth whilst this podcast is aerosolised around the world.Show notes for this episode hereSend us a Text Message. Support the Show.Questions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    85. Bordetella and the Cough of 100 Days

    Play Episode Listen Later Aug 5, 2024 37:10 Transcription Available


    You'll be whooping with knowledge after listening to this one. Come hear all about Bordetella species. From pertussis to kennel cough you'll hear it all.Show notes for this episode hereSend us a Text Message. Support the Show.Questions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    84. BIA Spring Meeting 2024

    Play Episode Listen Later Jul 22, 2024 29:23 Transcription Available


    Send us a Text Message.The Spring Meeting of the British Infection Assocation is a must for UK infection trainees; In this week's episode Callum summarises for Jame (who was there, but didn't take any notes) the main learning points from the meeting.Show notes for this episode here BIA membership is FREE to UK infection trainees, reasonably priced for everyone else, and paid memberships come with online access to the Journal of Infection! Sign up today at https://www.britishinfection.org/join.  Support the Show.Questions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    83. BSAC Spring Conference 2024

    Play Episode Listen Later Jul 10, 2024 34:21 Transcription Available


    Send us a Text Message.Jame was there but Callum wasn't! The British Society for Antimicrobial Chemotherapy have several conferences throughout the year, including a Spring meeting with their AGM. But what topics were discussed, I hear you wonder? WELL WONDER NO MORE: Jame'll take you through it! Notes for this episode here Support the Show.Questions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    82. Microbiome 2: Microbiotoxicity

    Play Episode Listen Later Jun 17, 2024 45:04 Transcription Available


    In this episode, the ID:IOTS Podcast Microbiome Correspondent Dr Anastasia "Tash" Theodosiou, finishes educating Callum and Jame (mostly Callum) on the concept of Microbiotoxicity!This episode is part 2 of 2. Here we discuss: - What is microbiotoxicity?- Risk factors for microbiotoxicity- Which antibiotics are associated with microbiotoxicity?- Mitigating microbiotoxicityhttps://www.researchgate.net/profile/Anastasia-Theodosiouhttps://x.com/doctoranastasiaSupport the Show.Questions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    81. Microbiome 1: Introduction

    Play Episode Listen Later Jun 3, 2024 29:32 Transcription Available


    In this episode, the ID:IOTS Podcast Microbiome Correspondent Dr Anastasia "Tash" Theodosiou, returns to talk about her favourite subject! This episode is part 1 of 2. Here we discuss: - What is the microbiome- Viewing the microbiome as an organ system- The microbiome's association with disease- How we study the microbiomeStay tuned for part 2 (in 1-2 weeks depending on editing), when we talk about the effect of medicine on the microbiome, microbiotoxicity, and what you can do to keep your patients' microbiomes in tip top shape! https://www.researchgate.net/profile/Anastasia-Theodosiouhttps://x.com/doctoranastasiaSupport the Show.Questions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    80. A Poem on POET

    Play Episode Play 26 sec Highlight Listen Later May 20, 2024 6:07 Transcription Available


    Join us for this special 80th episode celebrating Jame's favourite trial.https://www.nejm.org/doi/full/10.1056/NEJMoa1808312Prep notes (including the images referred to in the poem) here. Special thanks to the Wikiguidelines Endocarditis crew for their work summarising the evidence this poem was based on. Support the Show.Questions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    79. A Précis on Penicillin Binding Proteins

    Play Episode Listen Later May 6, 2024 32:33 Transcription Available


    Presenting: More on Penicillin-Binding-Proteins than you realistically ever need to know! What is the difference between Gram positive and negative bacteria's cell walls?What is a Penicillin Binding Protein (PBP)?Why are they called PBPs?What do PBPs do?What makes MRSA resistant to (most) beta-lactams?These any many more questions answered!Notion page here - you'll need it for this one, check it out!  Support the Show.Questions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    78. Pharmacokinetics summary

    Play Episode Listen Later Apr 21, 2024 26:29


    One PK table to rule them allOne table to find themOne table to bring them all And in the darkness blind them… …with awesome antibiotic PK facts you can use to bedazzle your friends and enemies alike! Prep notes here. Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    77. Illuminating Elimination

    Play Episode Listen Later Apr 8, 2024 43:29 Transcription Available


    The last Pharmacokinetics episode had finally been …Excreted!  This episode  covers the ‘drug out' bit of pharmacokinetics, including things such as:  -What is clearance? -how to calculate half life and -doesn't everything leave through the kidneys anyway? (That is sort of true, also shut up).  Check out our prep notes (including for this episode) here.  Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    76. Dithering on distribution

    Play Episode Listen Later Mar 24, 2024 41:21 Transcription Available


    It's the second Pharmacokinetics episode you never knew you wanted! Let's talk about how antibiotics are distributed around the body once absorbed, using the examples of Amoxicillin and CallumShutUpicillin (listen to episode for clarification).What exactly is the volume of distribution? Want a handy reference for the plasma protein binding of various antimicrobials? Then this is the episode for you! Check out our prep notes (including for this episode) here.  Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    75.Blethering about Bioavailability

    Play Episode Listen Later Mar 11, 2024 41:16 Transcription Available


    It's the Pharmacokinetics episode you never knew you wanted! Callum didn't know either, but never mind that let's talk about how antibiotics are absorbed, and how we can use that to improve our use of them in clinical practice. Want ammunition for that oral switch? Got someone who's doubting oral antibiotics' effectiveness? Then this is the episode for you! Check out our prep notes (including for this episode) here.  Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    74. Nobbling the Nonfermentors: Burkholderia mallei - Glanders

    Play Episode Listen Later Feb 25, 2024 24:57 Transcription Available


    In this final episode of the Nobbling the Nonfermentors mini-series, Jame and Callum discuss the (mostly historical) pathogen Burkholderia mallei, causative agent of Glanders. We did it. We got to the end. Nonfermentors... Nobbled.  Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    73. SABATaddendum

    Play Episode Listen Later Feb 13, 2024 5:56


    Post-publication, Callum and Jame give a little extra information on the SABATO trial in its final form compared to it's pre-publication state. Final article here:Efficacy and safety of an early oral switch in low-risk Staphylococcus aureus bloodstream infection (SABATO): an international, open-label, parallel-group, randomised, controlled, non-inferiority trial, Kaasch, Achim J Valiente, Adoración et al. Lancet Infect Dis. 2024 Jan 17:S1473-3099(23)00756-9.PMID: 38244557.https://doi.org/10.1016/S1473-3099(23)00756-9Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    72. IDIOTS journal club: the SABATO trial

    Play Episode Listen Later Feb 12, 2024 39:31 Transcription Available


    JOURNAL CLUB, YO, IT'S A SABATO!!!Join Jame and Callum as we travel back in time to when we recorded this deep dive into the SABATO trial pre-print, now peer-reviewed and published in the Lancet ID!In the next episode we'll give a little update as to how the final article differs from the preprint (not much). We also talked about in our FIS Highlights Episode 3. We loved this trial and we hope you'll all give it a read, it's well worth it! Article here:Efficacy and safety of an early oral switch in low-risk Staphylococcus aureus bloodstream infection (SABATO): an international, open-label, parallel-group, randomised, controlled, non-inferiority trial, Kaasch, Achim J Valiente, Adoración et al. Lancet Infect Dis. 2024 Jan 17:S1473-3099(23)00756-9. PMID: 38244557.https://doi.org/10.1016/S1473-3099(23)00756-9 Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    71.Nobbling the Nonfermentors: Burkholderia pseudomallei - Melioidosis

    Play Episode Listen Later Jan 29, 2024 39:43 Transcription Available


    In this penultimate episode in the Nobbling the Nonfermentors mini-series, Jame and Callum discuss the regionally important neglected tropical disease Melioidosis, caused by Burkholderia pseudomallei.This episode was based disproportionately on the following article, and we extend our thanks to the authors for thoughfully publishing it so close to us wanting to do a podcast episode on Melioid!Meumann, E.M., Limmathurotsakul, D., Dunachie, S.J. et al. Burkholderia pseudomallei and melioidosis. Nat Rev Microbiol (2023).https://www.melioidosis.info/Link to prep notes here. Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    70. Part 2 FRCPath reflections and Desert Island Antibiotics

    Play Episode Listen Later Jan 8, 2024 53:11 Transcription Available


    In this Episode, Callum reflect on his recent runaway success passing the FRCPath Part 2, passes on some tips and tricks for the exam, and then we talk about what 3 antibiotics we would take with us to a Desert Island (that has all pathogens and environments where you would find said pathogens, so not just a desert apparently). 'Prepping to Pass' episodes mentioned: 40, 42, 43 & 50.The Table and Links mentioned in this episode can be found here: https://idiots.notion.site/70-Reflections-on-Part-2-2023-a193fd830c9b4d6c9381107471fcdbca Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    69. Choosing an antimicrobial

    Play Episode Listen Later Dec 25, 2023 22:24 Transcription Available


    How do you think about antibiotics?This Christmas we give the best gift of all: no puns in an episode.Join Jame and Callum as they talk about a method for thinking about and explaining antibiotics.Here are the show notes for this episode: https://idiots.notion.site/69-Choosing-an-antimicrobial-4e7446a91ff6413aa14924a2ba905ffa  Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    68. Nobbling the Nonfermentors: Burkholderia cepacia Complex

    Play Episode Listen Later Dec 18, 2023 52:17 Transcription Available


    Did you think the  evidence base for Stenotrophomonas was bad? Well allow  us to introduce you to Burkholderia cepacia complex!BCC is pretty niche but a key pathogen in people living with cystic fibrosis. We talk through the (very) limited treatment options and evidence base for this difficult bug.Prep notes for this episode here: https://idiots.notion.site/68-Burkholderia-cepacia-complex-7bba8a7c74df490cb2e91d087a3cdb2aSupport the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    67. FIS highlights 3 - Fungal Diagnostics, Linezolid & Serotonin Syndrome, SABATO Trial, Rabies, PK/PD Dosing of Antibiotics

    Play Episode Listen Later Dec 4, 2023 31:33


    Callum and Jame wrap up their thoughts on the recent FIS conference. Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    66. FIS highlights 2 - Neurosurgical infections, parasitology reg, anti-fungals, NITCAR

    Play Episode Listen Later Nov 27, 2023 34:48 Transcription Available


    Join Jame, Callum and Pals for a discussion on some highlights from FIS 2023: https://microbiologysociety.org/event/full-events-listing/federation-of-infection-societies-fis-conference.htmlMentioned in episode:ESCMID brain abscess guidelines: https://www.sciencedirect.com/science/article/pii/S1198743X23003993# ORAL study protocol: https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-021-05783-8 ACBLM/ALM: https://www.acb.org.uk/Pathology networks: https://www.england.nhs.uk/pathology-networks/UCLH/HTD: https://www.uclh.nhs.uk/our-services/find-service/tropical-and-infectious-diseasesuclh.parasitologyspr@nhs.net Review article on anti-fungal resistance and global health: https://www.nature.com/articles/s41579-022-00720-1NITCAR website: https://nitcollaborative.org.uk/wp/Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    65. FIS highlights 1 - SNAP trial, AMR musical, S. aureus update, IPC in LMIC

    Play Episode Listen Later Nov 20, 2023 27:34 Transcription Available


    Join Jame, Callum and Pals for a discussion on some highlights from FIS 2023: https://microbiologysociety.org/event/full-events-listing/federation-of-infection-societies-fis-conference.html Mentioned in episode:UCHL HLH protocol and referral details: https://www.uclh.nhs.uk/our-services/find-service/medical-specialties-1/hlh-serviceSNAP trial: https://www.snaptrial.com.au/ SNAP trial email: snap-trial@unimelb.edu.auSABATO (pre-print) https://www.medrxiv.org/content/10.1101/2023.07.03.23291932v1RESISTANCE/The Mould that Changed the World: https://www.mouldthatchangedtheworld.com/ Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    64. Let's talk tests with Let's Talk Micro

    Play Episode Listen Later Nov 6, 2023 42:19 Transcription Available


    In this episode Jame and Callum are joined by Louis, host of the let's talk micro podcast.Listen in for a discussion on what a Biomedical Scientist is and how to become one. We explore the key details that clinicians need to add to their specimen request details; and ponder how laboratory managers can make this easier for clinicians.How to request a test:https://global.oup.com/academic/product/how-to-request-a-test-a-clinicians-guide-to-the-interpretation-and-evaluation-of-medical-tests-9780192866615?cc=gb&lang=en& Let's talk micro podcast:https://rss.com/podcasts/letstalkmicro/ Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    63. Nobbling the Nonfermentors: Stenotrophomonas maltophilia

    Play Episode Listen Later Oct 23, 2023 52:44 Transcription Available


    Ready for some startling Steno statistics? In this big 1-parter, Callum & Jame go through Stenotrophomonas maltophilia, from start to finish. Unlike Pseudomonas & Acinetobacter, Steno is much less commonly seen outside of ITU & the immunocompromised; but when it shows up you have to know what you're doing. Luckily for you, there's basically only 2 treatments! (In Europe: you'll see what I mean).2 crap puns in this one, so… get ready for that. Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    62. Nobbling the Nonfermentors: Acinetobacter Part 2: Resistance & CRAB

    Play Episode Listen Later Oct 9, 2023 43:05 Transcription Available


    In Part 2 of our episodes on Acinetobacter we talk abouit resistance, and then do a deep dive into the evidence base for the management of CRAB: Carbapenem-Resistant Acinetobacter Baumanii-calcoaceticus complex. Do have a look at the prep notes for this episode if you want more information on Acinetobacter. Links to podcasts mentioned in this episodeID:IOTS Episode 41: Bugs Without BordersFebrile episodes 76 & 77: Piece de (Gram-negative) ResistanceEpisode 76Episode 77For links to the papers we used, see the prep notes! Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    61. Nobbling the Nonfermentors: Acinetobacter Part 1

    Play Episode Listen Later Oct 2, 2023 26:56 Transcription Available


    In this episode, Callum and Jame go over the second big family of nonfermentors, Acinetobacter. In part 1 we talk about the organisms themselves, risk factors, clinical syndromes and diagnostics before talking a little about treatment. In Part 2 (released next week) we'll talk about Carbapenem-Resistant Acinetobacter Baumanii-calcoaceticus (CRAB), and resistance mechanisms in general. Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

    60. Nobbling the Nonfermentors: Pseudomonas Part 2 - Treatment & Resistance

    Play Episode Listen Later Sep 11, 2023 44:54 Transcription Available


    In part 2, we discuss the limited treatment options for pseudomonas infection, some wildcard options and the resistance mechanisms that make Pseudomonas such a tricky bugger to treat! Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

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